LOCUS       DADVXE010000001       100704 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.001, whole genome shotgun sequence.
ACCESSION   DADVXE010000001 DADVXE010000000
VERSION     DADVXE010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 100704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.001"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(553..2166)
                     /locus_tag="KB913_000001"
     CDS             complement(553..2166)
                     /locus_tag="KB913_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6818401.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2307..3215)
                     /locus_tag="KB913_000002"
     CDS             complement(2307..3215)
                     /locus_tag="KB913_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6818402.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3398..4522
                     /locus_tag="KB913_000003"
     CDS             3398..4522
                     /locus_tag="KB913_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6818403.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4749..5666
                     /locus_tag="KB913_000004"
     CDS             4749..5666
                     /locus_tag="KB913_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6818404.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5659..6492
                     /locus_tag="KB913_000005"
     CDS             5659..6492
                     /locus_tag="KB913_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6818405.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6575..7693
                     /locus_tag="KB913_000006"
     CDS             6575..7693
                     /locus_tag="KB913_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6818406.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7687..9585
                     /locus_tag="KB913_000007"
     CDS             7687..9585
                     /locus_tag="KB913_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBB6818407.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9579..10802
                     /locus_tag="KB913_000008"
     CDS             9579..10802
                     /locus_tag="KB913_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6818408.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10888..12822)
                     /locus_tag="KB913_000009"
     CDS             complement(10888..12822)
                     /locus_tag="KB913_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6818409.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13048..13704
                     /locus_tag="KB913_000010"
     CDS             13048..13704
                     /locus_tag="KB913_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBB6818410.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13778..14131)
                     /locus_tag="KB913_000011"
     CDS             complement(13778..14131)
                     /locus_tag="KB913_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBB6818411.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14323..15252
                     /locus_tag="KB913_000012"
     CDS             14323..15252
                     /locus_tag="KB913_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBB6818412.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15263..16099
                     /locus_tag="KB913_000013"
     CDS             15263..16099
                     /locus_tag="KB913_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBB6818413.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16347..17123
                     /locus_tag="KB913_000014"
     CDS             16347..17123
                     /locus_tag="KB913_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6818414.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17299..18042
                     /locus_tag="KB913_000015"
     CDS             17299..18042
                     /locus_tag="KB913_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6818415.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18035..19615
                     /locus_tag="KB913_000016"
     CDS             18035..19615
                     /locus_tag="KB913_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBB6818416.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19866..20345)
                     /locus_tag="KB913_000017"
     CDS             complement(19866..20345)
                     /locus_tag="KB913_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBB6818417.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20361..21113)
                     /locus_tag="KB913_000018"
     CDS             complement(20361..21113)
                     /locus_tag="KB913_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBB6818418.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21230..21300
                     /locus_tag="KB913_000019"
     tRNA            21230..21300
                     /locus_tag="KB913_000019"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21262..21264,aa:Gly,seq:ccc)
     gene            21661..22386
                     /locus_tag="KB913_000020"
     CDS             21661..22386
                     /locus_tag="KB913_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBB6818419.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22641..22907
                     /locus_tag="KB913_000021"
     CDS             22641..22907
                     /locus_tag="KB913_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBB6818420.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22904..23335
                     /gene="ruvX"
                     /locus_tag="KB913_000022"
     CDS             22904..23335
                     /gene="ruvX"
                     /locus_tag="KB913_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBB6818421.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23360..23665
                     /locus_tag="KB913_000023"
     CDS             23360..23665
                     /locus_tag="KB913_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBB6818422.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23746..24891)
                     /locus_tag="KB913_000024"
     CDS             complement(23746..24891)
                     /locus_tag="KB913_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6818423.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24952..25599)
                     /locus_tag="KB913_000025"
     CDS             complement(24952..25599)
                     /locus_tag="KB913_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6818424.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25793..26086
                     /locus_tag="KB913_000026"
     CDS             25793..26086
                     /locus_tag="KB913_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818425.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26130..26441
                     /locus_tag="KB913_000027"
     CDS             26130..26441
                     /locus_tag="KB913_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818426.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26438..27062
                     /locus_tag="KB913_000028"
                     /pseudo
     CDS             26438..27062
                     /locus_tag="KB913_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27203..27361
                     /locus_tag="KB913_000029"
     CDS             27203..27361
                     /locus_tag="KB913_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818427.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27362..27724
                     /locus_tag="KB913_000030"
     CDS             27362..27724
                     /locus_tag="KB913_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818428.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27761..28609
                     /locus_tag="KB913_000031"
     CDS             27761..28609
                     /locus_tag="KB913_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBB6818429.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28599..30074
                     /locus_tag="KB913_000032"
     CDS             28599..30074
                     /locus_tag="KB913_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBB6818430.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30340..30747
                     /locus_tag="KB913_000033"
     CDS             30340..30747
                     /locus_tag="KB913_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBB6818431.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30750..30965
                     /locus_tag="KB913_000034"
     CDS             30750..30965
                     /locus_tag="KB913_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818432.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30969..31349
                     /locus_tag="KB913_000035"
     CDS             30969..31349
                     /locus_tag="KB913_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBB6818433.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31483..31638
                     /locus_tag="KB913_000036"
     CDS             31483..31638
                     /locus_tag="KB913_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBB6818434.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31707..32180
                     /locus_tag="KB913_000037"
     CDS             31707..32180
                     /locus_tag="KB913_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBB6818435.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32177..33871
                     /locus_tag="KB913_000038"
     CDS             32177..33871
                     /locus_tag="KB913_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBB6818436.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33837..34022
                     /locus_tag="KB913_000039"
     CDS             33837..34022
                     /locus_tag="KB913_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818437.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34026..35201
                     /locus_tag="KB913_000040"
     CDS             34026..35201
                     /locus_tag="KB913_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6818438.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35194..36717
                     /locus_tag="KB913_000041"
     CDS             35194..36717
                     /locus_tag="KB913_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBB6818439.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36773..37057
                     /locus_tag="KB913_000042"
     CDS             36773..37057
                     /locus_tag="KB913_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBB6818440.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37044..37379
                     /locus_tag="KB913_000043"
     CDS             37044..37379
                     /locus_tag="KB913_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBB6818441.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37674..38300
                     /locus_tag="KB913_000044"
     CDS             37674..38300
                     /locus_tag="KB913_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818442.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39042..39878
                     /locus_tag="KB913_000045"
     CDS             39042..39878
                     /locus_tag="KB913_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBB6818443.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLINLYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39942..40373
                     /locus_tag="KB913_000046"
     CDS             39942..40373
                     /locus_tag="KB913_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6818444.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(40435..41757)
                     /locus_tag="KB913_000047"
     CDS             complement(40435..41757)
                     /locus_tag="KB913_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBB6818445.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41911..43551)
                     /locus_tag="KB913_000048"
     CDS             complement(41911..43551)
                     /locus_tag="KB913_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBB6818446.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43884..44354
                     /locus_tag="KB913_000049"
     CDS             43884..44354
                     /locus_tag="KB913_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBB6818447.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            44576..45679
                     /locus_tag="KB913_000050"
     CDS             44576..45679
                     /locus_tag="KB913_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBB6818448.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            45963..46643
                     /locus_tag="KB913_000051"
     CDS             45963..46643
                     /locus_tag="KB913_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6818449.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            46733..47767
                     /locus_tag="KB913_000052"
     CDS             46733..47767
                     /locus_tag="KB913_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBB6818450.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            47781..48116
                     /locus_tag="KB913_000053"
     CDS             47781..48116
                     /locus_tag="KB913_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818451.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48100..50580
                     /locus_tag="KB913_000054"
     CDS             48100..50580
                     /locus_tag="KB913_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818452.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            50636..52195
                     /locus_tag="KB913_000055"
     CDS             50636..52195
                     /locus_tag="KB913_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6818453.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52192..53556
                     /locus_tag="KB913_000056"
     CDS             52192..53556
                     /locus_tag="KB913_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6818454.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            53727..54797
                     /locus_tag="KB913_000057"
     CDS             53727..54797
                     /locus_tag="KB913_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6818455.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            54812..55480
                     /locus_tag="KB913_000058"
     CDS             54812..55480
                     /locus_tag="KB913_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6818456.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55500..56078
                     /locus_tag="KB913_000059"
     CDS             55500..56078
                     /locus_tag="KB913_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6818457.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56479..57390
                     /locus_tag="KB913_000060"
     CDS             56479..57390
                     /locus_tag="KB913_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6818458.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(57478..58395)
                     /locus_tag="KB913_000061"
     CDS             complement(57478..58395)
                     /locus_tag="KB913_000061"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBB6818459.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            58597..59034
                     /gene="zapA"
                     /locus_tag="KB913_000062"
     CDS             58597..59034
                     /gene="zapA"
                     /locus_tag="KB913_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBB6818460.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59093..59641
                     /locus_tag="KB913_000063"
     CDS             59093..59641
                     /locus_tag="KB913_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBB6818461.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            59756..62116
                     /locus_tag="KB913_000064"
     CDS             59756..62116
                     /locus_tag="KB913_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBB6818462.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62203..62517
                     /gene="trxA"
                     /locus_tag="KB913_000065"
     CDS             62203..62517
                     /gene="trxA"
                     /locus_tag="KB913_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBB6818463.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            62699..64477
                     /gene="uvrC"
                     /locus_tag="KB913_000066"
     CDS             62699..64477
                     /gene="uvrC"
                     /locus_tag="KB913_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBB6818464.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            64622..65521
                     /locus_tag="KB913_000067"
     CDS             64622..65521
                     /locus_tag="KB913_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6818465.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            65514..66776
                     /locus_tag="KB913_000068"
     CDS             65514..66776
                     /locus_tag="KB913_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6818466.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            66937..68835
                     /locus_tag="KB913_000069"
     CDS             66937..68835
                     /locus_tag="KB913_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBB6818467.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(69165..69884)
                     /locus_tag="KB913_000070"
     CDS             complement(69165..69884)
                     /locus_tag="KB913_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBB6818468.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            70221..70553
                     /locus_tag="KB913_000071"
     CDS             70221..70553
                     /locus_tag="KB913_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818469.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            70540..72543
                     /locus_tag="KB913_000072"
     CDS             70540..72543
                     /locus_tag="KB913_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBB6818470.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            72562..73032
                     /locus_tag="KB913_000073"
     CDS             72562..73032
                     /locus_tag="KB913_000073"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBB6818471.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73053..73637
                     /locus_tag="KB913_000074"
     CDS             73053..73637
                     /locus_tag="KB913_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBB6818472.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            73652..74638
                     /locus_tag="KB913_000075"
     CDS             73652..74638
                     /locus_tag="KB913_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBB6818473.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            74628..74939
                     /locus_tag="KB913_000076"
     CDS             74628..74939
                     /locus_tag="KB913_000076"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBB6818474.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            74961..76742
                     /locus_tag="KB913_000077"
     CDS             74961..76742
                     /locus_tag="KB913_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBB6818475.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            76735..78111
                     /locus_tag="KB913_000078"
     CDS             76735..78111
                     /locus_tag="KB913_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBB6818476.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78118..78753
                     /locus_tag="KB913_000079"
     CDS             78118..78753
                     /locus_tag="KB913_000079"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBB6818477.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            78783..80138
                     /locus_tag="KB913_000080"
     CDS             78783..80138
                     /locus_tag="KB913_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBB6818478.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80330..81724)
                     /locus_tag="KB913_000081"
     CDS             complement(80330..81724)
                     /locus_tag="KB913_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBB6818479.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            81816..82787
                     /locus_tag="KB913_000082"
     CDS             81816..82787
                     /locus_tag="KB913_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBB6818480.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            82784..83566
                     /locus_tag="KB913_000083"
     CDS             82784..83566
                     /locus_tag="KB913_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBB6818481.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(83735..84106)
                     /locus_tag="KB913_000084"
     CDS             complement(83735..84106)
                     /locus_tag="KB913_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6818482.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84240..84683
                     /locus_tag="KB913_000085"
     CDS             84240..84683
                     /locus_tag="KB913_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBB6818483.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(84726..85535)
                     /gene="yidA"
                     /locus_tag="KB913_000086"
     CDS             complement(84726..85535)
                     /gene="yidA"
                     /locus_tag="KB913_000086"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBB6818484.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNNEHGVAEAIKKYVL"
     gene            complement(85554..86921)
                     /locus_tag="KB913_000087"
     CDS             complement(85554..86921)
                     /locus_tag="KB913_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6818485.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(86905..87735)
                     /locus_tag="KB913_000088"
     CDS             complement(86905..87735)
                     /locus_tag="KB913_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBB6818486.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            87898..88335
                     /locus_tag="KB913_000089"
     CDS             87898..88335
                     /locus_tag="KB913_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBB6818487.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88411..89031
                     /locus_tag="KB913_000090"
     CDS             88411..89031
                     /locus_tag="KB913_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBB6818488.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89220..89726
                     /locus_tag="KB913_000091"
     CDS             89220..89726
                     /locus_tag="KB913_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBB6818489.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            89743..90642
                     /locus_tag="KB913_000092"
     CDS             89743..90642
                     /locus_tag="KB913_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBB6818490.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            90729..91613
                     /locus_tag="KB913_000093"
     CDS             90729..91613
                     /locus_tag="KB913_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBB6818491.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(91805..91876)
                     /locus_tag="KB913_000094"
     tRNA            complement(91805..91876)
                     /locus_tag="KB913_000094"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(91841..91843),aa:Arg,seq:ccg)
     gene            91936..93270
                     /gene="rpoN"
                     /locus_tag="KB913_000095"
     CDS             91936..93270
                     /gene="rpoN"
                     /locus_tag="KB913_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBB6818492.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93419..94510
                     /locus_tag="KB913_000096"
     CDS             93419..94510
                     /locus_tag="KB913_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBB6818493.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            94551..95552
                     /gene="gap"
                     /locus_tag="KB913_000097"
     CDS             94551..95552
                     /gene="gap"
                     /locus_tag="KB913_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBB6818494.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            95662..96852
                     /locus_tag="KB913_000098"
     CDS             95662..96852
                     /locus_tag="KB913_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBB6818495.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            96956..97711
                     /locus_tag="KB913_000099"
     CDS             96956..97711
                     /locus_tag="KB913_000099"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBB6818496.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            97827..99125
                     /gene="eno"
                     /locus_tag="KB913_000100"
     CDS             97827..99125
                     /gene="eno"
                     /locus_tag="KB913_000100"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBB6818497.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            99524..100663
                     /locus_tag="KB913_000101"
     CDS             99524..100663
                     /locus_tag="KB913_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBB6818498.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        33405 a        17204 c        20781 g        29314 t
ORIGIN      
        1 gttaaataaa taggaacaaa aaaattaaat tatttaatac acacattagg gatcattcat
       61 tgaaggatta gaagacaacg aggatggcga aaaatatgat tacaatagaa aagtcgttct
      121 aaaccaatca gttcctagta tcacacaacg caagccagtc gatttggtga gattagagga
      181 gtgaaagcaa actttattat ataagaaaaa atattcgaaa gggatgctag tttaggtact
      241 agtgctgata gattaatatg atgcctcgta atattaggcg tagttactct agagacatca
      301 ctatggacta tgatttgtct cagagtcaca acatgttttt ttatgaaaag aaacagctaa
      361 aataattaaa ttgcgcaatg tttaaacttt cttaaactat aacctaataa atgtgaagaa
      421 ataatgcaca atttcttcac atttatcttc tattctatat acataccaac caacaaccct
      481 atatactttt tcatttttac tcctcaagta aaaataactc ctagaccgcg gctacccacc
      541 gcggtcgttt ttttattctt caatcaaaat cgctttgata cccaaacctg ccaagattcg
      601 ggcagaagta taagtattca atcctcttct gaaagtaatg taaacttttt tatcttttgg
      661 gatttcattg attcgatctc gtaactcatt cattggaata ttttttgttg ccgagatact
      721 gccagaaggt gctttattag gttcacgtat atctaaaaag aacgcttctt tcaaatcgtt
      781 ttcgggtata tcacttgctt tgatcgtttc tacgatattc gtcatttgat tgattgcgac
      841 ataaccagct atattcaacg ggtcacgggt agtagaatac ggtggagagt aaggcaactc
      901 caaatcaggc aaatcaaaga ctgtcaagtt tccggtgatt gctacagaaa gttctcccat
      961 ccgtttatcg acaccttttt ctccaaatgc ttgtccacct aaaatacgac cgctatctgc
     1021 atcaaaaatc agctttagat ttaatcttgt agcttctgga tagaaatagg catggtcaaa
     1081 gggagtgata aaaacagttt tataatttgt tatgcctgat gcttttaatt catgttctgt
     1141 cattcccgca taacttgctg tatgatcaaa gatttttgcg acacctgcac caatatatcc
     1201 gcgatagcgc ataggcgtac catttaaaat atctgccagc atatgtcctt gacgattggc
     1261 cgcactggaa agcatacttt ggatcggctg accagtcact acactagtcg tttcgataat
     1321 atcgccaatc gcatagatgt ccggcagatt ggtttgtaac tggtcatcaa caatgatctg
     1381 acctgtatct gataattgta tgccggttgc tttcaccact tcattcttcg gagaaacacc
     1441 aacagcaaaa attagcatat cagcagaaag gacggagcca tctgataata ctatttctcg
     1501 acctttatca cggatctcag taactcttgt ttctaaatga acggctaatc cttctttcag
     1561 caatttgtca taaactaaat tagcaatttc tggatcataa gggaaagcga cttgtggcaa
     1621 ttgatcgatt aaagtcacgt ctaagccgcg atgcttgaaa ttctcagcta attccagacc
     1681 cataacacct gcaccaagaa tgacgacatg ttgtggattt ttttcttcaa ggaacgattt
     1741 gattcgatcc gcatccgtca cactacggag gacaaagccg ttttctgctt caaaaactcc
     1801 gggaatatcc ggataatctg gtctagcacc agaagagatg atcaacttat cgtaatctgt
     1861 ttttatttct tcatttgtgg ataggtcttt aactgttaat cgcttagtag aaggatcgat
     1921 tgctgttact tcgtgtttag taaagacatc gatgttgttt tttgttttca atatttctgg
     1981 tgtacgttcg atcagcgagt cacggtcagt gatcacacct cctaaataat aaggcaaagc
     2041 acaacttgca taagaaatat tttctccgcg ttcatagata atgatttcgt gcgcttcatt
     2101 caatcgacgg aaacgagtgg caaatgaagg accgccagct acaccgccaa tgacaacaac
     2161 tttcataaaa acatctcctt ttctacgttg atcgtactat gttatggtaa aaaacagcaa
     2221 ataattgtgc cggaaaatta ttgtttattt tgaatagaca gaaaatatag agaaataatt
     2281 tgtggataaa acctaaaaat ttttttctat tttaaggata gataatactt tgaaggggat
     2341 aaccctgtat attttttaaa agctgaagaa aaatgatgga tcgaatgaaa tcctaatata
     2401 tctgcaattt ctgtataggt taattcattt tctagcacga gacgttttgc tttttccatt
     2461 tttagttctt taaaatagct aataacactt tttccattca cttttctaaa atgttttttt
     2521 aagctggctg gactgataaa aaaaatttgg gctaattgtt caagcaaaaa attttctgaa
     2581 agatgttctt ctaaatatcg tatgattgga tcaactaatt catctgaata aagaatatgc
     2641 ttttttttag gaatgacttt ctcatttgaa ggtattgtca ataaagcaag ttcctgttga
     2701 taatgccttg gtaaggaaga caattgaatt ttttgcagac aataagtaac taataaggaa
     2761 agcaaatgaa tgctcatctg ttggcatagt atgaaaaaag aattgatttc ctgatcatag
     2821 gaaatagctg gcttactatg ttttagataa tcaattttga actgttcatt tttcagaaaa
     2881 gtaatgatag atgttatttc ttgatctata gaaaaagatt gtcccgtaat atgtgctaat
     2941 aattgctcat caaaataaaa ctggataatg ataaaagttt gtgtttcctt ttgagtagaa
     3001 aagatttgga cttcttgctg tttatcaatg aataaaaggg aaggattatc tagttctata
     3061 gatttatgtg caaattcagc atataaatta gcgctttcat ttattagtag tcgaaaatag
     3121 ggagcagcag ataaatgaag atgggtatct atggaatagg ttagtgtttt tttgacaaga
     3181 ttggaggatt ggttgtttgt taacaaaaga accactttcc tttctctttt tatataaaaa
     3241 gctttctatt tataattaat gactattata acaaaaatga aaagccaaaa cgacaagtaa
     3301 aatatttttt tatataaata tttgtgttac taattccgtt aatatacata agtgaaagcg
     3361 ttttatataa gaacttgaaa agaaagaagg gatagacatg aaaaaaagat acaaattggt
     3421 gatagctttg ctaaacatta ccctattatt cagcttaagt gcatgtggaa aaactaacga
     3481 agaagtaaca gcaaacatcg cagatccaat gataaaaaaa gccactacat tagaagtata
     3541 tgtcgcaaac ggcaaactga caaactatgt tgaaaatgct gcaaaaatct ataaccgcaa
     3601 aactggagca aatattgact taaaaattgt gaatgtagct tcgggaacag caacagtaca
     3661 aatgatcacc ccaaaattgg taacacacga agatatgccg gatattatct ccatggcaga
     3721 cacttcagca gcaggtgtgc tggaaaaatt tcaagatgct ttttatagtg ctgatgaata
     3781 tggattttat gacaaatatg gcgatcagtt ttatgatcaa aaattgaata ttttgcgtca
     3841 acaaacgagt aatgaaacga ttattccttg ggctagtgat tttaccccag cactttgtta
     3901 ttatcaacca aaaaaatttg ctgaaatagg tgtagatttt gaagaaatca gttcttggga
     3961 agaatatatc caggtggcaa aagcattaaa agaaaaaact ggtagttttg gaattgcctt
     4021 gccagaatct ggggaccaag aattgtttat caacatgcta gcccagcaga atcaatcttt
     4081 gcttgatgaa gaaggaaata tccgtctgaa tactaaagaa gcgaaacatg ctgcaaagtt
     4141 aatcaaagaa atgatcgact cagatattgt acatttctac ggtgcacaag atgctgagaa
     4201 agcatttcaa gaatctgcaa tgtttgttgc tggcggctgg tatgctacga atatgtcttt
     4261 gaattttcct gatgcatctg acaaatggcg catggctcca ctgattcctt tttcaaaaga
     4321 aaatccagga aaaggtgcag tatcaggagg atcaagtttt tatgtcccta aagatgcaaa
     4381 aaatccacaa gtggcacaac aatttcttac atttatgctg acagatgaag aatgcttagc
     4441 caacgcactg gagctgggcg tggctacatc taactcattg gcctatcaaa cagaagcagc
     4501 tgagaaaaag tttgactact aaggaggaca aaaatactat gaactattga ataaaatcaa
     4561 tgaaaataca tcaaatactg ttttaccagc cacttattca gatgctacgt cttatttgac
     4621 taccgctgca tataactatt ggcaaacagg tgattttgaa aattcatatc taaaagaagc
     4681 agaaaatttt gctcataagt acggcgtaaa attaactggt gattaaaaaa tattaggagg
     4741 acttaacgat gatgcaatct tcgttaccaa gcaagacaat aaagaacagc aagaaaaaag
     4801 caacagatac gtctcataaa aaaagtgctt atggattggt cacacctttt gttattttct
     4861 ttattgtgac gattttgatt cccatcatta tctcgtttgc ttttagtttt atgaaaattg
     4921 gctactcatt tgaatttgtt ggatttgaca attatctagc tatcttccga gatccattgt
     4981 ttattaaatc ttacacgaat gttttgatta tcatggcagg atcaattcca ataacgatgc
     5041 tattagctat ttactttgct gttttattga attcagcaca gttaaaagga aaaggatttt
     5101 ttagaactgt ctattatatt ccaaccatta catcaacggt ggctgtagct tccgtattca
     5161 tgactttttt caatccgact gggttattca atggattttt gaatgcgcta ggaattaacg
     5221 gtgtacagtg gttaacaaat cctttttgga tacgaatatc aatgatcatc acgatgattt
     5281 ggcttagtgt aggatataac actattttat ttttagctgg tcttcaaggg atttctaaag
     5341 agatatacga aagtgctgaa atagatggag catcgaaatt tcggcaattc tttttattaa
     5401 cgatccccat gctaaagcca atcattttaa tggccacagt tttagccact atcaatggct
     5461 tgggtaattt caatatccca aatatattct ttgggacttc caatggacca gaaaattcag
     5521 ctttggtcgt aggagtcaat ttatataaaa caagttttga aatggttgat tttggaaaag
     5581 cctctgctat tgcctggacg atggtgtttg tatctgttat attatcggct attcaattta
     5641 aattcggagg tgataaaaat gactaaacaa aagatacaaa gcagaatttt tacgtacgtc
     5701 attattgtgt ttggtgcctt aatatttttg atgccatatt tatatatgat tgtagcttca
     5761 acgcaaagta atcaagaaat tttaagtggc ggaatcaatt tcaagtttgg ggatatgcta
     5821 ttaaaaaact ggcaagccat catggcgaga tataattatc ccttgattat ttggaattcg
     5881 attgttattg ctgtaatcag tacagtttta gctacagcca gttctacaat ggcgggttat
     5941 gcattagcaa agtatcgttt tatggggaat aaactgttgt tcaatacagt tatgctatct
     6001 aggatggtgc ctttttttac cacattgatt cctttatttt acattatgag tcgtttagga
     6061 ttatcgaata cttatgcagg tgtgatcatc ccttcgattg ccagtacaac ttcagtgttt
     6121 atgatgcgac aatatagcag tcaatttcct acagcactga tggaggctgc cagaatcgat
     6181 ggtgccaatg agtgggtgat ttttacgaaa atcgctgtac cgattttatc acctacgatt
     6241 attactagtg gtttacttat ctttatggga agttggaatc aatatctatt tccattagtc
     6301 atgctttcag ataaagataa atatacggtt cccttaatta tcaaaaatat gacggtttct
     6361 agtacaggtg agccaattaa ttatggcgca attatgctaa ttttagcaac ttcagtgatc
     6421 ccaatggtct tgatttatgt gtgggcgcag tctaaattta aggagaatga cattggagct
     6481 gcaaataagt aaaaaaaata acgaatgtta accatctagt tcgttctagg agcaactcca
     6541 cattcataaa aattaaaaga atggcgggat atccatgaat gaacagacga aggaatggtc
     6601 aagaaaaatt ttgaatgtag cttctgaaaa gatagatgcg gaattagaca gaatggggaa
     6661 taaaattcca tatatttctt acaacggaaa atatacagac gtaataaagg acagaggaat
     6721 cgactggtgg accaatggtt tttggagtgg tattttatgg cagctctttc acaagacaaa
     6781 acgagaaaag ttcaaagagg cagcaataca acaagaacaa ttattagaat ctgccctgta
     6841 ccatttttca gacgttcatc atgatgtagg ttttttattc ttaccatcgg ctattgcaca
     6901 ttatcaacag tctcaaaaca aacatagtcg acaactaggg ttacatgcag ctacggtact
     6961 tgctggacgc tataatattt cagggaacta tttagtagca tggaatgacc ataaacctgg
     7021 ttggatgatt attgatagta tgatgaattt accattactg tattgggctt cgagggaaac
     7081 tggtgatccg aggttctcta aaattgctcg gcagcatgca gatacaacag ctaagtatct
     7141 agtgaggaaa gatggatcaa ccgggcatat cgcagaattt gatgcagaat cagggaaata
     7201 tattcggtta cttggcgggc aaggatacaa tgagaattct tgttggagca gaggaaatgc
     7261 atgggcttta tatggattcg cgttaagtta tcgttacaca aaaaatccgt actatctagc
     7321 tatagcagaa aagatagcag taaattttat tcagaaaatc gaaaaaactg gttatattcc
     7381 tctcattgat tttgctgtaa aagattcgaa tattgatacc agtgctggag tatgcgctgc
     7441 atgcggtctt ctggaattag caggatatgt ttcctctgta cgatcaaaaa tgtatcatga
     7501 agctgctatc aatatactcc aaaagacaga aaagcactat gcaaattgga atatggatga
     7561 agatgggatc attggaggcg gagcagaagc ataccataga gaactgactt ataatgtgcc
     7621 actgatctat tctgattatt tttttattga aggcttactt cgattagaac agtcggaatt
     7681 agctatttgg tagtaaaaag aggagaaaat acaatgaaac atccagtacc actattaagg
     7741 accagacagg attactttga cttatttaaa aagataaatc aaccactcca gccgttttat
     7801 cgagcaagtg gcgcacaaat tgattatata catcaagggg taggatatgg aaataaaatt
     7861 gcaggaatgg aaggattctc tcgggtttta tggggagcgg ggcccgcaat tgaccaatta
     7921 gatgaacgat ggttgaaatt aattctatca ggaataaaag ctggaacaga tccttcccat
     7981 cccgattatt ggggagaaat acatgaaaga gaccagcgta tggtagaaat gcccgcaatg
     8041 ttattagcgt tatatcatca tgaacaatta ttatggaaaa aattagatac aggagaaaaa
     8101 agccagatta ttcattggtt ctcgcaaatt tttgaatatg aatgtgcaga tggtaattgg
     8161 caatttttta agataattgt cggaacaatt atccaaaaat ttggttatcc agttaaagaa
     8221 tcagcactga aagaagcatt tgataatata gaaaattgtt atcttcaaaa tggctggtat
     8281 cgagacagtt caagaggtcg ccaagattat tataatcctt ttgcatttca ttattatggt
     8341 ttgatttata gcgtactaga accagaaaag cccattagcc agatatataa gaaccgagct
     8401 attgattttt ctagagacta tattcatttt tttgcggaag atggtgcaaa tgtgcctttt
     8461 ggtcgaagca tgatttatcg ttttgcagtt tcaagctttt ggtcagctat gttgtgggcc
     8521 gatcttttgc cttttaaatt aggtgaaatc aaggggttag tcaatcggaa tataagatgg
     8581 tggatgcaaa aagaaatatt tgatgaaaaa ggtatcctga atattggtta tacctaccct
     8641 caattgacat tgactgaacc ctataatagt acgttatctc cattatggct gaataagatt
     8701 tttttattgt tggcgctacc tgaagaccat gagtattgga cggctaaaga aatgcctatg
     8761 cctattcgtg aaggaactaa acttctttca gaagccaatt tgctcataca acatgataat
     8821 ggacatacat tttttttgaa tgcgggacaa ttagggccaa atttccatac attgaccaat
     8881 gaaaaatatt taaaatttgc ttattctagt caatttggtt tttcgatacc gcgagcgaat
     8941 caattgaaag cagaaatggc aatggattca atgctaggga ttcagcgagc ggacacatat
     9001 atcacgacca gttttaagaa tgagagcatc aaaacctatg gacagttcat cgttcgaaat
     9061 aatgtacgag acattgtatg taagaaagag gtacttgcct ctacatggga acctacttta
     9121 caggcaaaaa tcagaacttg gcttattcct tttgaaggct ggcagattcg cgtacacaaa
     9181 gtagaattag atacagaata tgttctatat gagacagggt ttgctattga atgttctcct
     9241 gagaaagaag gaataatcat agaagaagac aaggaaaact atagggtgag tgaagctggc
     9301 ttttcaggta ttatctgttt aagtgacgat actattaaac gaaaatccac agctattatg
     9361 ggtttgccca atacaaactt gatgacatgg gaaaacactt ttattcctgg attagagggt
     9421 acatttggaa aaggaaccca ttggctcgga acaggagtgg ttgctcatca agatcgggat
     9481 tatagtttag aagtatggaa caatcgtccc aaaattgatt ttgatgggac aaccgggcta
     9541 actatccaaa ataaaaacaa taaaaaaaga ctaaaattat gctaaaggct ggtggggaaa
     9601 tgcttgataa agtgatgttt gaagagataa tacatccaga aaaatggata aatgaatgtt
     9661 ataaagaatt aatggaaaaa gaatggaata atgagatcga gcgttgtcgc agacacacgg
     9721 agaggttaat caaacgtatc agtaacagtc agtatcaatt cccaagcgag tgtcctataa
     9781 aaggacgtta tccattaaga gacaatattg gttggacaga aggattttgg acaggaatta
     9841 attggttgtt atttgagaag acgggtgatc ctttatttca acaaacagct gaaaaagcag
     9901 atatagattt tatccacagg attgactgtc aaattatcac taatcatcac gatcttggtt
     9961 ttttgtattc tttatcaacc gtagcagatt ataaaataac gggaaatcga aaaatgaagg
    10021 aagcttcaat tgatgctgca gaaacattac ttcagcgttt ttgggagaag gcaggagtta
    10081 tacaagcttg gggagatcct agtgatcctt cacaacaagg tagaatgatc atggattgtt
    10141 gcatgaatct tccattattg tattgggcga gtgaagaaac tggaaatcaa aaatataaaa
    10201 aagctgctca ggctcatatt caaaatgcag cagattattt agtaagagaa gatggttcaa
    10261 cttatcatac attttatatg gatgtcaaag atggaaaacc aagatatgga agtacgcatc
    10321 aaggttatag tgataattcc tgttgggcta gaggccaagc atgggggatt tacggttttg
    10381 cattaagtta tcgttatttg aaagaacaaa aatattttga tttaagcaaa atattagcca
    10441 attattttat gaatcggttg ccagaagata ccatttgtta ttgggatttg atctttgatg
    10501 attctagcag agaagaaaaa gatacatcta gtatggtgat catggtttgt ggattattag
    10561 aattaataga atcaggtcta ttagacaaaa cagaaaagaa cttataccag tctgctgttt
    10621 ggaaaattat gcgacaattg aaagaaagat atgctacaac ggaagaagaa gatggctttt
    10681 taacacagtc tgtttataat aagcccaaaa ataatggggt aaatacacct tgtatttggg
    10741 gtgattacta ttatttagaa gctttagtga gaatgactag taattggtct tcttattggt
    10801 gaaaaaggta aatatggaat ttttgtttga taaaataaaa aaagaaaaac caaaacagca
    10861 tgaatggttt ctgttttggt tttttcgtta attttcatat tcttctaatt ccaagcttag
    10921 ttcttcccat tccgtcaatt ttgtttcttg atcttgtcta gcagcttcta aatcttggtt
    10981 cagctcattg agttttacgt gatcttccag gttttctggc gcgaccattt cttgttccaa
    11041 ctgatcgatc cattcatcga tccgcgccat ttcttcttca acctgagtaa tttttcgttg
    11101 aaggctacgg ataagctttt gctgttcttt gctttggtaa taatcagatt tgttcgtggg
    11161 agcaggagca gattctggct catcttgtgc caacaattcg gcgatttctt cttcttcctg
    11221 ctttttctct aaataataat catagtctcc tagatagact ttgctgccat tttcagagag
    11281 ttcgacgact tttgtcgcga tccgattgat gaaatatcgg tcatgggaaa caaaaagcag
    11341 tgtgccgtca taatcgatca atgcattttc taatacttct ttgttgtcaa tatctaaatg
    11401 gtttgttggt tcatccaaaa tcaaaaaatt ttctttgttc atcgctaact tggctaaagc
    11461 aacccgtgct ttttcaccgc cacttagcag agggattggt ttttctacat cttcgccaga
    11521 aaataagaaa gcacctaaag cacttcggat ctctttttct ggagtggtag gatgctcatc
    11581 ccacaattct gctaggatcg tcttgtttgt atgcagatca gcttgacctt gatcgtaata
    11641 gccgatggtg acatttgtcc ctagcgtttc ttttccacgg ataaaaggga tctggtgaat
    11701 gattgatttc agcaacgtcg atttcccgat accattcgga cctactagag caatcgcttc
    11761 ttgacgacgg atatctagat tgattggttc agataaggtg acattatcat atccgatagc
    11821 ggcatcttcg atttgcaaga ctacatttcc agaaggcttt tctatactga atagaaagtt
    11881 tgcttgtttt tcatcccctt gaggacgatc cagccggtcc attttttcta atgtctttct
    11941 gcggctttgc gctcgttttg tggtagaggc gcgaacaagg ttccgagcaa cgaagtcttc
    12001 taatttatgg atttctgttt gctgcttttc ataagccttc cattcacttg ctaactgttc
    12061 tgctttcaaa tctagatatt tcgaatagtt acctttgtaa tggcgcattt ttcttctgct
    12121 taattcatag acttcattga ctactttatc taaaaaataa cggtcatggg aaacaatcaa
    12181 taatgcacca gtatagcttt gcagataatt ctcaagccag gaaagtgtct cgatatctaa
    12241 atggttcgtt ggttcatcta gaatcaaaat gtcagggtgt tgcaaaagca tgcgagctaa
    12301 agctaaacgt gtgcgctgtc cgcctgataa agtatcgatt ttctgatcat aaaatgaaga
    12361 atcgaattta aacccatgca atacggaacg aatttcattt tcataaccat agccgtttcg
    12421 atctgaaaaa tcgtgttgca gccggtcgta ttcttttaaa taagaactat aagcaggtgt
    12481 gtctggcgta ccttcgctaa tgaaaatctc tagctcgcgc atccgctctt ccatttgtct
    12541 aacttgttca aaagctttca gcatctcgtt ccaaactgtt tcattggaat caagtcctgt
    12601 gtcctgagcg aggtatccga gagtcgctgt tttattttta gcgatctttc cttcatcagg
    12661 tgcttcaatt ccagcaatga tctttaataa agtcgatttt ccagcgccat ttctgccaac
    12721 taaagcgaca cgagcgcctg tactgatttc taaatgtatg ttttcaaata agacttctgc
    12781 accaaaatgg cgagcaatct gattggcttg taataatatc atggaatcct cttttctact
    12841 ttgtgaattc tcctcaaata aaaaactatt tttcaattag tagtctacca taaattccat
    12901 tatactgcga gatttgcaga aatgataaat aaatgaataa agaataaaat ttcacaatat
    12961 ctgagcaatg gaattgattt tttcctataa atactgctat gatggagaaa tcaaagatgt
    13021 aattagacaa tacgtggagg tcatttcgtg aaagatcata ttattccaaa ggcgacagct
    13081 aaaagactgc ctttgtatta tcgctattta aggattttaa ataatgctgg aaagaaaaaa
    13141 gtgtcttcaa ctgaattaag tgaagccgtt caagtagata gtgcaacgat ccgtcgagat
    13201 ttttcttatt ttggcgaatt aggaaaacgt gggtatggtt atgatgtaga agatcttatg
    13261 cacttttttg caaagacatt aaacgacgat caattgacaa atgttgcgct gatcggtgta
    13321 gggaacttgg gaagtgcttt actaaaatac aaattccatc aaagtaatag catacgtatc
    13381 agttgtgctt ttgatgtgaa tgaggaaatc gttgggcgca tcgtagacgg tatccccgtt
    13441 tatccaatgg aagatatgtc agaacaaatc aagatccaac aaatcgaagt agcaatttta
    13501 acgatacccg ctgaaagagc acaagaagta gtcaatcagt taacggaagc aggaatcaaa
    13561 ggaatcttga actttaccgc tgctcgattg aatgctccgt cagatgtatt gatccaaaat
    13621 gttgatttga cgaatgaatt gcaaaccttg atctatttct tgcattctga cgcaaatgcg
    13681 cattccgaaa atacagcaga ataaaaataa aaagcgattg aacaaatgaa ggcaaaactt
    13741 tcacttgttc aatcgctttt ttctgtttgg acaacgatta ttttgttcgg aagatttctt
    13801 cataagaaag ggaatcatct tctgctgtca gttcatctag tagataacgg atttttttaa
    13861 agtcgatgaa ccgtgcttgc cgaaagactt cttttccttg atgaaaaatc aggacaactg
    13921 gcgcagtcag cacttcaaat ttactagcta cttctggtgt ttcaaatgca tccaaatgaa
    13981 gtgccggaat atcataatgt gtgagaagtt cctctagtcg tggacgaaca gcgtgacaaa
    14041 cactgcaatt aggcatcgaa agataaatga cggcaacgga tgactgttgc agtatgtctt
    14101 gaacttcagt caagttagtg gtttgtttca tttttattct cccttttatg atagaagtga
    14161 tatgtatgag accttaattt aatgggaata acagaaaaag tcaattgaag tgctttggta
    14221 aaaaataaga gttgtgtaaa aatttacaga gcaacttgtt ttttttgaat aaaagcgtat
    14281 atttgcaaag cgaatgaact agaaataaaa aggaggaaac tcatgttttc ttttattcca
    14341 aattcggttt tgcagatgag tacgattttc ttatcgatcg ttattgaagc attacctttc
    14401 gtattattag gctgtcttat ctcaggcgcc ttacaagtat ttttgacccc agaacgtgtg
    14461 aagagatggc ttcctgaaaa tcgtatcttc tctattttta ctggttcgat cttaggattt
    14521 ttctttcctt catgtgaatg cggcatcgta ccgatcgttc atcaatttgt taaaaaaggc
    14581 gtaccagttc acacagcgtt tgcttttatg ctgactgctc cgatcatcaa tccaatcgtg
    14641 attttttcca cttttatcgc atttggcaat tcttggcaga tggcaagctg gcgggtgata
    14701 ggcagctttt ttgttgccct tgtgattggt gtctggcttg cctattttca aaaagacgct
    14761 gtattgaaag aaaaaatcac gtctaaagta gcagaaaatc accatcatca tgtccatgaa
    14821 gaagaacaaa gtgagaagaa tgaaccaaaa aatcagctga tccatcaaac tgggcatgtg
    14881 ttgacacatt caatcgacga attttttgat acaggtcgtt atttgatcat tggcggatta
    14941 atcgcagctg cgatgcagac ttatttacca actagaatta tgctaacgct cggctcaaca
    15001 aagattttag ccattatcat catgctgtta ttggccttta cgatgtctct ttgctcagaa
    15061 gcagatgcgt ttataggatc ttctttgtta agtctgttcg gcacagcacc tgtagctgcc
    15121 tttttggtct ttggcccaat ggtcgatatc aaaaatctac tgatgatgaa acgatatttt
    15181 acaggacgct ttattttatc gctgatcgga ctgattgccc ttagcgttat tggattcaca
    15241 ttatttattt aggagggaaa atatgctgcg gtttttgatt ttatctgggt atttcgaatt
    15301 gatgatgtac ttgcaagttt ctggcaaact cgatcaatat atcaatgtcc attatcgcta
    15361 cttagctatt ctttcaatga ttttatctgc tcttttggct ttagttcagc tgtatttgtg
    15421 ggtcaaaaac ggaaaagcag aagaaaaggc acacgagcac gatcatgacc atgggttgtc
    15481 aaaaccttat caacgtggaa tcgcttatgt actgctagct ttgccagtaa tcgtggggac
    15541 gttgtttcca acagttagtc tcgacactac gatcgtagaa gccaaaggat ttaatttccc
    15601 agtaagtaaa gaatcagtag gggatccgga gatgcagaca caatacttaa agccggatac
    15661 cagtatttat ttcaacaaat cagactactt agaccaaatg aatgagttga aagaaaagta
    15721 tggggataag caaactatca agatcacaga tgaaaactat ttagaagtta tggagctaat
    15781 ttataattac cctagcgaat tcattggcaa aaaaatcagc tatgaaggat ttgtttacca
    15841 aacaccgaac gatagcaata cagatatctt cttgttccga ttcggcatta tccattgtgt
    15901 ggcagattca ggagtctttg gtttgttgac gcatatgccg gaaggagtaa cggttaaaaa
    15961 tgatgaatgg tataaaatag aaggaaccat ccaatcagac tattatcaac cattcaagcg
    16021 tgaaatccca tctgtagttg ttacaaacgc tgagaaagtc tctgctccga aaaatcagta
    16081 tgtgtatcgt tctttttaaa agaacaaaat aaataaacat agctcagaca gctgacacgc
    16141 aaggacgtcg gttgtctggc tttttttgca tgatgtattc atttgtttga tatttatttt
    16201 agaagcagca tcctgaaagt atttgatatc ggtttcaaag gtgttggaaa agattgtgaa
    16261 gagaattaca atttattcct aacatgtatg ttgaaaagtt gtatgaaatg attttgatag
    16321 taaaatatcg agtggaggta ctttttatgg taacgcgtat atttattttg gatgatagtt
    16381 tggtttttga aaaaatgcta gtagaaattt tggaagaatc cagaatttta ttaagtcctt
    16441 ggaaatttga gatcgttcag ggattgaacg ttatacaatt tgttgaattc attaaaaata
    16501 atgaaatcta ttcctcagat atttttttcc tagacatcga tttgaacgcc tattatagcg
    16561 gtatcgaact aggcgaaatg cttagagaaa agaatgaaaa gtgtaaaatt gtttatctaa
    16621 cgtctcatcc gaataaagca ataactgtta ttaatcgaaa gattacgcct agtggttatt
    16681 tgataaaaga attcacttat gaaaaaaata aaaaaagcat ccaaagttac ttattgaaag
    16741 aaaaagaaaa ctatcctgtt caacatgcta cgaaaaaaag gtggacaact gtccgttatg
    16801 gtaatagcga tcactatatc cattacgatg aaatccttta tctaatgagc atgccaggtt
    16861 ataaaaataa aataggccta gtattgaaag atgaagagat tctcgtaaac ggcacaatta
    16921 aaaaatataa aaaatcactc gaatatgagt atttatgtaa agatttaaaa gcttatatca
    16981 ttaatactga aaacattaca tctattagca gagtaaacga aatagtaaca tttgcaaatg
    17041 gagaacaact agagatggga aagagaagta ttgataaact aaagaatttt atgcaagaaa
    17101 agatagaaaa tgaatcattt taaagaaaac aaagactcat atcttacctg ttagaagagt
    17161 gttttcctgt agaagagaac aacccaagta gcagcctagt cgtttctatc cttttttgtt
    17221 atgcactctt tttgacattt actccaccaa taacgaaggg tacaataaaa agtaataaca
    17281 aacaaaagga gtacagaaat gattgaattc atcaatgtaa gtaaaagtta cgggaaaaaa
    17341 caagcattaa aagacttgtc tctctcgata agacaagggg aaatttttgg atttttagga
    17401 cataatggtg ccggaaaatc aactacgatt aaaagtttag ttagtattat tgaaccatca
    17461 tcgggaacga ttttagtaga tggaatgaaa ttgacggaaa atcgattgag tatcaaacaa
    17521 aaaatcggtt atgtgcctga ttccccagat atttttttac aattgacggc tggagaatat
    17581 tgggacttga tttcagctgc ctatgaatta gacacacaaa aaaaagaaaa gcgtttagca
    17641 gaattgacag cgctttttga tatgtatagt catcaaaatg aaacaatcgc aagtttttca
    17701 catggaatgc gtcaaaaaac gattttgatc ggcacgttgc tgccagatcc agatatttgg
    17761 gtattggatg aacctttgca aggacttgat cctcaagcag catttgattt gaaagaaatg
    17821 atgaaggctc atgccgcaaa aggaaaaaca gtcatttttt ctacacatgt attggatacc
    17881 gcacaacagt tatgcgataa actggctatt ttgaagaaag gtgaattgat ttatcagggg
    17941 gcagttagtg aattattgaa tggctcacct gatgaaacgc tagaaaagat ttatttgaaa
    18001 atggctggaa ggcaagcgac aggagatgga ccgtatgtat aagcgacaat tattagaatt
    18061 aattcgagtt aatcttttat atgttaatcc acagctcacg aataaagcaa gagagaaagg
    18121 aaaaaaggga aagcgattaa ctatctatct tttgtctcaa aatctttttt cagggctgat
    18181 ttttttactg atttacggat ttgctatgtt tgctatgaac tttgttaaat tgccaggttt
    18241 ctttacttat tacgtggcac tttttggtat gttaggttta actcaaagta tatcagtcat
    18301 ttataatatc ttttttgaag gaaatgacct gcaagtattt ttgcctctgc cttttggaca
    18361 agaacaggtt ttttcagcaa agattttggt agttgctttg accatcattc cttttgtttt
    18421 tccgcttcta gtcatgttta ttttaaccgg atggcgagct gatctaggga ttttgcttac
    18481 tatcattatc tcaatccttt tgttttctct atttttgatt attctttttt gtctggctag
    18541 tttgattgtt tttggtttgg ctcgaacagc agtgtttaaa aaacatagaa aaacagtttc
    18601 tagtatcttg cttggcagct cgatgctgat cgcatttgct ggaatcatgt ggatgaatca
    18661 tcaaacgggg actattgaaa atgagttaac agatcggcat ccgatttcga tattattgcc
    18721 attctatgat gctgccagtc agccactttc tcaacaaggt ttattgggtt ggggaatact
    18781 agctatcacg gctctgggat ttttccttgc tgtaaaacag ctgatagtac caaagcttac
    18841 agagcaactg actgattcaa acagtgagtt caaaataaaa agaacccata aaaagaacca
    18901 aaatgtgcat cagcttttat ttagttacaa tgctcaatta gtaaaagaac ctaatttgat
    18961 tatgcaagtt ctttcttctt ccttgttaac tccaatcatt tttattcttg cttttgccct
    19021 aggaggcgaa ataaaattaa ctgatttaga taataagtta atcggtgttg ttttcctggt
    19081 agggatcgca ttggctttct taacagttaa tcagacttct tttatcagca atcttatttc
    19141 tttggatcaa gaaaattttc tgtttatccg ttctttgcca atctctatga accaatattt
    19201 aaaagaaaag ttcagattcg gatggatatt gcagagtttt ttaactggtg ggatcgcatt
    19261 attaagcgga ctgtcttttc agctgccttt gttttttatc cctagcttgc tatttggttc
    19321 tttattcggc tgctacttat tgtcactacg ttatttcgct agagattatc ggttgctgct
    19381 gctgaactgg accaatatta accaattatt taacagaggt tcaggaagtt tgggtttagt
    19441 cgcaactatg atgggttcat tgatcatcag tattattctt atcgtcttat acggaatgtt
    19501 ggctttgttt tatccatttt ggttagtgaa tattcctgtg atcggtttag ttctaatact
    19561 ttccgctcta tggatcgttt attatcaacg aacgttttgg aaaaaatttg aataaagaag
    19621 aggggccgtg acaaaaatca tgtcgcagcc ccttttttac agatagaggg tgttcaaaag
    19681 tcagtttctc agtattaagt caattttatg taaaaatgtg agaagctatt tttacaaaac
    19741 tttttttaat actcataatt acttcttatt gctcctgcgg ttacttgtcg caatgtttgt
    19801 gagatatttt gtcatcgctc aaggctgaac gtctctttca caaccttttc tttgttacac
    19861 ttcgtttatt taaaaagccg tttttttcgt ttcatcatga ttgcgtcacg ctttactttg
    19921 aaattacgga tgttatggtt aaagacttct gataatacaa gacctaaagc gattgctcca
    19981 gcaatcataa ttgcttggac cgcataatga gccgcttctc gataggattc agtaacgaga
    20041 tttcgaaccg cttgataagc taaaccacca gggactagag gaaccatccc gggaatattg
    20101 aaaatcgtta cgggcatttt caaacgttta gagaaaagat cgctgatgaa tgctactcct
    20161 aaagaaccaa gcaatgaacc aaaagcagca gatccgccta tttgaacaca gatccagtag
    20221 atcatccagc caaaagcacc agaaagacca caacaaatca atgaacgcct aggtacattt
    20281 gtaataacgg caaatgccgc agtcgctaaa aaactaaaag aaaactgaat aaatatcgtc
    20341 cccatacttg tgttcctttc ctaataaaaa agctggaaaa taaaagcaat cgcaaaaccg
    20401 atcatcgtag cagtcatcat cgcttctgtt ccgcgagaaa ctcctgagac ataatgtcca
    20461 gctagcaaat cacggatagc gttcgtaatt tgaactccag gaactaaagg catcacacat
    20521 ccgataatga ttagatcctg attgcttcct aagccaaaac gtacgctgta gatagcggct
    20581 atgccaatca ataaagaaga taaaaattcc gataaaaatt tgattctaaa aaatttcaaa
    20641 ctatatagat aagctgcgta tcccaatcct ccaatgacta aagtcacagg taaatcggtc
    20701 atctttccgc caaataacac cataattgtt ccactgatca ctgccgcgct aacgatttgc
    20761 aaccagacag gaaagaaaga acggtctcgg tcgattgctt gcagttcgca gtaaagttct
    20821 tctaatgtta gctctgaagc aacatattta cgtgaaagat catttacttt tactactttt
    20881 tctaaattaa tcgaacggtt ggtaatttgt tccattcgga tggtcgaggt acgatcaaga
    20941 ccaataaaga gaccggtttg agtgacatag ctgaccaaac ggaaatttcc agaagctaaa
    21001 gcaattcgac tcatcgtatc ttctacccga tacatctccg cattgctttc catcatgatt
    21061 ttcccagcga gtaaacaagt gtccagcaac agatctaatt cttttcccgt catagcatct
    21121 tctccaataa ttgattgatt agttttattt tactacaaaa cataccagaa gcgtaaagaa
    21181 taaaaaaact tgaggaagga ataaaagagg cgtatactgt ttttgtattg cgggtgtagt
    21241 ttagtggtaa aatcccagct tcccaagctg atgtcgcggg ttcgattccc gtcacccgct
    21301 taaaataggt tgtgaaaaag ctgctctgca acaagtaata agaacagcca agcaaaaaca
    21361 acttcttatg tttttaactt ggatggactt attaccgcag atgcaagctt ttgcgcaccg
    21421 tttaccaagc ggttgtgaaa tcagtgtatt gtcttgagta tgaagaaaat ttttgaataa
    21481 taataaatac cttacagata gagtggtgac tgattagaga cgaggaatcc gtctcttttt
    21541 tgtattttta agccatctta aaacaggttt tattttttgc tgtttctatt tctttctagt
    21601 atttatttat aggggaacat atgttaagat ttagggagct gttagtaaag gagtaaagaa
    21661 atgagcaaaa aaacaaccaa ggcgatcgtg gggatcgtcg ctgctgtgat tgcaggggca
    21721 ttcggtgttt ccaccacaca aaaagattca gatatctttc agcagattac aactattttt
    21781 gattccacac cacaagcttc tcaagtagcg gatgtgccag aatatgatgg aaaacatcaa
    21841 gaaatagaaa tcaatgggaa tcagccggaa tttacaaaag aggatcttag cctttccaaa
    21901 ggaacatggg aaagctattc aaatattgat aaattgaaca gagtaggaca agccaatgct
    21961 atgcttggaa aagatttgtt ccctactgaa aagagagagc ctttgtatat tgacccgaca
    22021 ggttggaaac aaaagaaatt aagtgacggg caatggttat ataatcgcag ccatttaatt
    22081 ggtttccagc tgactggtca aaataacaac attaaaaact tgatgacagg gacacgttcg
    22141 ttgaatgctc catacatgct tgctcacgaa aatgatattg cggcatatat caaagaaaca
    22201 aatcatcatg tacgctaccg tgtcactcct cattttgagg ggaatgaact ggtagccagg
    22261 ggagtgcaat tggaagcaga aagcattgaa gacaaaaaaa ttgaattcaa tgtctttatc
    22321 tacaatgttc aagatggcta cacgatcaat tatgagacag gacaagcaac aaaaacaaaa
    22381 aattagtagc agctattcga attttttatg aatattatga aaaaattgtg taaaaacata
    22441 cattcaaaga aatatagcgt atactttatg aaaagagtac ttttgataaa gctacagaaa
    22501 aaaggaaaaa aacatacaaa tagtgtttct taatttattc ggaagtttgg aatatttgtt
    22561 tgtagttttc cctttcttcg agtaaaataa ggttgtagaa ggtaagctgg aattaccttg
    22621 cgggaaagag gtgtagaatc atgggtttta cagatgaaac cgtacgtttt ggttttgacg
    22681 atagtcgcaa aaaagaagtg agcgaaacat tagcgattgt ttatcgggct ttggaagaaa
    22741 aaggctacaa tccaatcaat cagattgtcg gctacttgct ttctggagac ccgtcctaca
    22801 ttcctcgtta tcgtgatgct cgaaatttga ttcgccgtca cgaacgcgat gagatcatgg
    22861 aagtaattgt caaggactac ctctcaaatc atggagtgaa tttatgagag taatgggctt
    22921 ggatgtcggt tctaagacag taggtgttgc tatcagtgac ccctttggct ggacagctca
    22981 aggagtagag atcattcgga tcaatgaagc agaagaagag tttggctttg atcggttgaa
    23041 ggaattagta gcacaatatg aagtagaccg gtttgtagtt ggattaccta aaaatatgaa
    23101 caattccatc ggaccaaggg cagaagcttc catgtcatac ggagaaaaga tcaaagaact
    23161 attctccttg ccagttgatt atcaagatga acgattaacc actgttcagg cagaacgtat
    23221 gctagtagag caggcaaata cttcaagagc caaacgaaaa aaagtcatcg ataaattagc
    23281 agctgtgatg atcttacaaa attatttaga cggctcaggt aagcaattat tttaataata
    23341 aaagaaaaga ggtaatctta tgacagaaca taaccattcc cacgaccatg aaggacacga
    23401 acacatcaca ttggtggatg accaaggaaa tgaaacatta tatgaaatcc tactaacagt
    23461 tgacggacaa gaagaatttg gacgtaacta tgttctttta tatcctgctg gtgtttcaga
    23521 agatgaagat gtagaattac aagcttatgc atacatcgaa aacgaagatg gaacagaagg
    23581 cgagttagaa caaatcgaaa cagacgcaga atgggacatg attgaagaag tattcaatac
    23641 attcatggcg gaagaagaag aatagactat aaagctagga gaaaccttga tatgataggg
    23701 tttctccttt ttttattttt tactgtatgc catattgtat gccatctagt caatatttaa
    23761 gtgttgtact aatttttcaa cagtcttttc tttcgtttct tttgccaagt gaccgtaaca
    23821 atcgatcgtc tgactaattt ttgtatgccg taatctagtt tgaacttcta ccatagtagc
    23881 tccagcgtcc aagagcattg aagcatgagt gtgtcttgct acatgcacac cgagaaatgg
    23941 aaccatagct ttttcacaaa tagtaatcaa tcttgcataa atagcgtggt gtgtgattag
    24001 ttctttatag ataccacaaa aaatcatagt cggatcagtt acaccaagtg tcagcatata
    24061 tttccgctga ttaatctgcc atttttttaa tatagaaatt gttctttcat ctagtggaag
    24121 aaccccagca ctacaatcag ttttaggatc actgatttta tagccatttt tggattggct
    24181 tagtgtttta ttgatggtga ccgtattttc ttgaaaatca atgtctgacc aattcaatgc
    24241 aagggcttca ctgatcctaa ccccgctata aaagagaaag cgtagtaacg ttttatcaaa
    24301 gtcgtttcga taagtttcag gtttgctgtt taggtaatca aacaaggtga tcagttgttc
    24361 tttactgtaa actttgacct tttctttatg cttagtggtg gttcttttag gcattaatac
    24421 gttgtctagt ggattagtct caataatccc aagattgata gcgtagctaa aaatacgctt
    24481 agaagttgaa tgaagtacct tgtattggtc agtagtttca gcccagctat ttacaatttg
    24541 ttgggctttt tttaccgtga cttcattcac acgaagattt ccatattttg gaagaatcca
    24601 ctttctaaac ttgatttcag ttttcatgaa ggtggcttct cggacagtgg ttttatatgt
    24661 ttctagccac aagtcataaa cttctttaaa cgtttcgttg ttcgcttttt taataccgtt
    24721 tttatcgtag tccacttgca agcgtgacaa ggcaagctgg gcttcttttt ttgttttgta
    24781 acctcgtcta cgaaccttat caggtttgcc agtcattttg ttcattccaa gataggcttc
    24841 atagagccaa aatttacctt ttttagtttc atattgcttg aatgttgcca taatagtttt
    24901 ccctccatag tgtagcaagc cgtgggggcg gttggaggag gcagtttatt attattttga
    24961 atagtgttta tttagctcag taacaagagc tgtgaactct tttagaagat cattttcata
    25021 aaattcttga tactcttttt tctcatctgt atttttttct gaatcattaa ttaatgagtc
    25081 atatcgtaaa agcgtattta gaagagctgc gagataagca attggggtac tcccgtcagg
    25141 aaattcaatt cgagatcctg ttttaagata ttttattgcg tttgttaaat aaatcttctg
    25201 tgagacagtc aggttatctt cttcgatgtt attgatagca ttagaaagat tagaatcaat
    25261 tatagagtta tttttttcaa tagttttttt caattgcttt tcaagcacat ttcgcttaat
    25321 ttcgggcatc atatgcatat ctcttaatgt ataagatccg tttaatagat aggtagtgga
    25381 tacatctaat acctttgaaa gttgtttaag cctggtgtta ttgggaagat tatagccatt
    25441 ttcccaatta ctaacggcac ctttactggc cggtggggat aatttacctc caagttgttc
    25501 cattgagagt cccttttcaa ttctagccag tctaattctt tgtcctgtct ccactgcttc
    25561 ggggtatttt tttctagcca cattttcacc accattcata tattttctct actatatcac
    25621 gatttaaata tgtgtgaaac ataaaagttc aaaaaagtat gttaaaattc ttgcaaatga
    25681 aaaggtatga tggtatattg agtttataag aggtatagaa atgtattcaa gagcctcttg
    25741 cattttttta aaatctttgt atagaaatgt atgctaacga ggggggataa atatggaatt
    25801 aaaaattgac aaactcacgc ttgatgatcc agcttttaaa attattgacg atcgagttgt
    25861 tcaacaagta gagcaaactc aaggaacgtt actttcatta ttagaaaaaa agtaccagtt
    25921 tccaaaatat atgaacaagg cacaagctgc taagtatatg aacgtttcat acaatactat
    25981 gatgcagaaa tatgttccta acggtttaaa gttgattata gttgatggag tcgtaagaat
    26041 ttcacaagat gaatgtgatc gctttatgga agaataccaa aaataaacgc aagccgtggg
    26101 ggcaaaggga ttaataggag gaaataataa tggaatcgac acaaaataaa gcaatcgaaa
    26161 aagtattatc aacaattctt acagaagaca cagcggcaga attagcaaac ttggaaggca
    26221 aagcgctaga agaaacgttt gaatgtttgt acgaacaaat ggactatcaa aaattgctac
    26281 cacaagaacc aacggtaagc ggagtattgc gtggcttgaa cgatttagta caagcagagt
    26341 ttaaagaacg actttctatt gaagagtatc aagaaatttt gtatcagcaa gttgagttgt
    26401 tagcgagctt gctagggctt gaactggagg acgttgaatg aaaactgaaa tttggaacgg
    26461 acacattata agatttgtcg atattaatga tgaatggtgg gcagtggcga aagatgttgc
    26521 ggaagcgtta ggtcttaaac aggttactag agccattcac tctttgccta aagatggggt
    26581 tactactagt aaggtcatcg attcattggg cagaacacaa gatgtaaaca tcatcaacga
    26641 aaaaaaatat ttaccgcatg gcattcaaaa gccgtaaaaa agaagccgag gcatttcaag
    26701 actggatttt cgacatcatc aaagaactac gccagtccac aggacttgaa ggctttcaag
    26761 tattccgcat gctagacaaa gaacaccaaa aagaagcaat gactaaatta agccacgcta
    26821 ttactgaacc aaaaccagta gactacatta aagcgaatgt gatagccaat aaagctgtat
    26881 caactattta tggtcattcc aaaatggtaa aaaagaaaga tatgactcct gaaatgttgg
    26941 ttgatcgtga acctatttta gatgagacag tagaattaat gactgttaaa gaaaaatatg
    27001 ggttgcagtt ttcagtgagt gagaaaattt ataatcgttc tgctgaattg cagacaactt
    27061 aggagcatta acatgatcga gaacaaagaa aaagccttat ccataacagt cttggcggac
    27121 aggataaagg caacttaatt gggataaaac ccgatattct ttgttccgat tataccatat
    27181 taaaaaatcg gagggaacca ttatgaaacg aaacttaatt ataggaagca ttttaatcgg
    27241 cggaattttc ggcttattac cattaattgc aaaaatagct atctttgcag gattagcgtt
    27301 atatctcttc actgcttatg acgagtacga ctatcaatta agaactggag ggcataagta
    27361 gatgtacaaa acaaaactat taaaccaact cgatagcctt gaattagagg aaattaatca
    27421 agggatcgct gaactagaaa ataatatcgg gaaaacctac tttggaaatt cattcaatga
    27481 aaaactaaca gttttgtatg tactcaaaaa acatgcagaa cacaaaataa tttgtcgaga
    27541 aatcaacgag ctaaaaaatc agattttaac cgcatggtta aacattactg atatgcaaga
    27601 agcaagggtg aaaacattta atacatgggt aaagtatcag aatcaattaa aaggtgctga
    27661 atttgttcgg gatgggttga aatacgaact tgagcagttg aagctcatgg aggtgtctga
    27721 atgatttata ccagtatttt gaaaaaggag gagaggttta ttggcaaata attatcaagc
    27781 agcaacggaa ttacaaaagt cgggatggtc aatttatccc ttatctcctg gaactaaaat
    27841 tccaataaaa ggctctagtg gttggaatga tgcaactaac gattctaatc aaattaatga
    27901 atggtggacg gaagatgcaa ctagaaatat tgggttaatg cttgaagatc atcaaatggt
    27961 ggtagttgac ctagatcaac attctgaaac acgaaacggc gttgagaatt ataaaaaact
    28021 tgcttcaatg tatgatccat ttccttctac ttatacggaa atcacaccag gtaaaggaat
    28081 ccatttcttc tttaaaattc ctgatggtgt aattatccaa caagaaacag gtgcatttgc
    28141 tgatatcttc gggcgtgatg ataaaggtaa aagtttaagc gggattgata ttatcactaa
    28201 aggagttcca atagcgccaa ctatgattat ttcaagaagt gttgggagag catatgaacc
    28261 tattgaaaac gtatctctaa ataatattgc accagctccc gattggctag tgaacctact
    28321 gctaaaaaaa ccgcaagaaa taaagactca ataccgaccc gtagcaaaaa cagggacagc
    28381 aaaaaaatta gatatgattg ttcaaggcgc tggcgaaggt agtagaaacg atcatttaac
    28441 taagttatgc ggttggttac tatggcacgg tgtagataat caaactttag cagaattgat
    28501 ttatacagca aatgcgtaca atgaaccacc gctaaaagat aaagaagtga atcaaattat
    28561 tcgatcgatg attaaaaaag atttgagggg gaaagctcat ggctcataag cataaattag
    28621 atagtatttt agactttccc gaagccagcg agcgtgaaga caatatcatt gaattgaaaa
    28681 cctggatgtc acgattaaga tgcaataaag acgatcagat taaaagtaac agtgttgtga
    28741 atgcagaatt gattttaacc aatgatagca atttagctgg aacaattgct tataacgaat
    28801 ttagcggata cattcaccta ttaaaagatt ctccttggat caatcgtacc gctggagaat
    28861 gggaagacag ttttgaggat gccttaacgg catatattga agaaaactac aatgtagttt
    28921 ttgatgacaa caaaatacac aaagcagtag taaatgtggc tagaaagaat gttttcaacc
    28981 cagtaaaaga acgtatcgaa aaagttaaat gggatcaaca gcctagactg gaaacactgt
    29041 ttattgacct tttaggggta gacgacaacc tttacacacg agaagtaaca aaacgttgga
    29101 tagtcggatc agtcgcacgt atctataaac caggaataaa gtttgagatc gttccagttt
    29161 tggatggacc gcaagggatt ggtaagagta ccgttccagc attactttac acggatgatt
    29221 ttttcaccga ttcattagat tcgctaggtg aaaagaaaga tgattatatg cagcttcaag
    29281 gcaatgtaat tattgaactt ggagaattat cttcaatgaa caaaactaaa attgaacaga
    29341 taaaaaactt catcagtgcc aagatcgata aaattagacc tccttatggt cggaatgtca
    29401 tagcttgggc aaggcaatgt gtatttattg gaacgtcgaa tgatgggcag tatttgaaag
    29461 atgatacagg aaaccgccgt ttttatcctt tgccttgtaa gaataagcca aagatgaatc
    29521 cgtttaaaac aaaggatgaa tattttcttc aagtgttagc tgaagcaaag gtgctttttg
    29581 ataaaggaca acgaatctat tttagtcccg atgaagataa agaagtctta gaaattgcaa
    29641 aagactatca agaggatgcc aagatggaga atccaattaa agaagcaatc actaaatatt
    29701 tggaaatgga aatcccgtat aaatgggaag aagctccagc gtgggcgaga cgttcttatt
    29761 atcagaacta tcctgacagt aaatgtaatg agaaaaattt acagcatttc tataatggag
    29821 ctactatgca acaagagttt tatttagttg atagcgtact caccgctgat attttggaag
    29881 ctgtttttga taaacaagca aaggatttat tgaatggtcg atcagatgca gaaactaaaa
    29941 agattgcctt gattattagc agtattcctg gttgggaacg gaagcaactg ccaaaaagaa
    30001 ataaacgacg aggattttac aataagtcaa atgcctatga aaataaaaat cgagctggaa
    30061 agtacaaaaa gtaacgggta gtaacgggtc agtaacacct agcccgttac tagtttaccc
    30121 ttactgcccc aagggataca gcaatttggt aacggggtaa caccttattt ccttaaaact
    30181 tttgaaatag ttagctaata tgctggggaa taatgttact ggattttacc cgttacctgt
    30241 taccaaaacg ctagaaccct tgtccccgtt gggattgagt ggtaacgggt acctgttacg
    30301 taggtgttac cacgtgttac gaatcaagga ggaaagtaaa tgctcaatat tatttcaaca
    30361 aacaaagcac cgaactttca atatacagat gaaatggatc ggtttctaat gaacacgctg
    30421 gcatttagtg tgggattggt aacagaagat tattccacat ttgatccaga agtattaaag
    30481 ataatggaag aagaacctga ttggctgcag gagtcagtag cgtggtgtca atcgctagta
    30541 gtgggatcat tggtagatag tggcaactat gatgatacag gtgagctaat ggatgaattt
    30601 aattgtctgc ttaacctata tgatcgagcg agacaacgag agcttacatc gaatgaggat
    30661 aatttgtttt taaacatcca tgataagttc ttggctttgc tactaacaga tgatgaattg
    30721 ataactaatt tattggaggt agaataatta tgcatatgga aagtattaga tacttcgatg
    30781 gtgagaaaca cattgagtat tcaaacactc aagaagatgt agactttatt agttttgagg
    30841 aagataaaat cactaaagtt aattttaaag acggaacgtg cttgaagata gtttcgcctt
    30901 atattgaata caaatcaaaa tgggaacaag atgattctga cgaacgagat cgctttggtt
    30961 ggtaatctat ggcagttaaa aaacaatgta atcatgctgg atgtaaaaca ttgattgatt
    31021 ataggcagaa gtattgtggg aagcataaag caaagcaaac ggcaattaag cgtgaagaaa
    31081 gaaagcaaag cgaaggtaaa tattttcaat tctatcaaag tagaacatgg cgaaaggctt
    31141 catacttgta tcggttaaat catccagtat gtgaggattg cctagaagaa ggcttgataa
    31201 ggaaagctga tgttgtagat cacaaaattg aactaaaaga tgattggaat agacggttag
    31261 atgaaactaa ttttcgttct ttatgccatg cacaccataa ttccaagaca gccaatgaaa
    31321 gacaaagacg agaaaagagt accctttgag ttaagggggc atagtgtgaa acttactgac
    31381 aatcgatgcc tactcatttt ggtacaaata accgttgtga aaaggcataa gggtaattac
    31441 aaataacgat tacacttgta atcacaagtg aaaaagtata taatgaaagt aggagattta
    31501 ttgaaaaata caattgttat tactgataaa acagggaaac agcgcaccat tgagttacct
    31561 cattttggtc aagtgaccat tcaaatgcag aacggaaaaa tcatttatat agataaatta
    31621 gataaagaaa aattctgatc gaaaaacgaa ggaatgtgag cttaattgct tacgttcctt
    31681 tttcttttgt ctgaaaggag gacaacatgg gacaccctaa aatattacac gatacaaaag
    31741 gcaatatatc aagtgaagaa aaagcaatcc gtgtggacgc tagagaagaa ttgttcaagc
    31801 agcaaccatt aataaatatc acgccccctg actggatggc agcgagcgct agaagtgaat
    31861 ggaatcgtat cgtaccaaca ttaaaaaaag attatccatt gagtgaagca gattatggtt
    31921 cattggtagc ctattgttta gcctttgctc gaatgaaaac agccgaagcc gagataagaa
    31981 aatcaggtac gtttatcaca tgcgaaaacg gagtaaagaa agccaatcca gcggttcggg
    32041 ttcaatcaca agctatgagt gatttgaaaa aacaagccac ctcactaggt atgaccttag
    32101 aatcacgatc aaaactagct ttgaacaagg ttaaaaatga tgaacccgaa gacccgttca
    32161 aagagttgat gaattcatga atgattacat tgagaaagtc ctatcaggta agctgattgc
    32221 acccaagaaa attatccaag cgtgtgagcg tcatataagc gatttggagc gttctaagtc
    32281 agatagcttc ccttatgtgt tcgatgaaga acaagccacc aaagcgatta aattcattga
    32341 gttgctacca tctacggacg gtaaagcaat caagatgtta ggatttcaaa aattcattct
    32401 aggcagtctt tatggctggc gtactaaaga agggaattac aggcgattca atcgagcgtt
    32461 taccagtatg agccgtaaga atgggaaaac gtatatcgca agtggcatgg ctgccaatgc
    32521 gttgattatg gaacaagaac cagcagaagc aaggcaagta ttgtttgtaa gtaacgcttt
    32581 gaaacaagct aaattgggct atgatatgct gtctaattca cttagaaacg tggtcaagtc
    32641 tagtaagttt ttaagaccac aactgaaaat tatgaactct aagattcagc acttgccctc
    32701 taattcgttc gctatggcac tggctagtga aaccagcacg ctagatgggt ttgcaccaac
    32761 aaccgcaatt cttgacgagt ggcacgaagc aaaaactcgt aaaacgtaca acgtcattaa
    32821 gtcaggaatg acccaacaaa agaacggctt attgtgtgtt attagtaccg ctgggcttga
    32881 tttaaacgtt cctatgtacg aggaatactt attgttagat cgtgtgctaa aaggcgaaga
    32941 acaagccgac aggtacttta tagcgatatg ggaattggac gatcccgaag aaattcacga
    33001 tcaagagaaa tggatcaaag ccaatccgat ttttgaaagt gaagaaatca aaaaagtaat
    33061 gattccaacc attcaagatg atgtgaacct tgctttgaaa caaaataacc ttaattctgt
    33121 attggtgaaa aacttcaatt tatggagaca agcgagtgag gacagctata tgattgctga
    33181 agactggcag gcaaccgaag tagaaccaca agatattaca ggcaagcccg tttatatcgg
    33241 agtggattta tctaaaacag atgatttaac tagcgtttca tggatcgtac cgctagataa
    33301 cggcgaactt tattgtgatt cacatagctt tgtagccacc aaatatgggc ttcaagacaa
    33361 agaaaagcgc gacggtttgc cttatcgaga actagaaaaa gctggtgagt gttccattac
    33421 tcaattagaa agtggaatcg tggactatga ccaagtattt cagtttattc aagatttgat
    33481 tcaagaaaat gatttggaat gtatggggat ttgttatgac ccgtataacg ctaattcgct
    33541 tatcagtaaa gctgaaaaag ccaactaccc aatgttagaa gtaagacaag gaacgattac
    33601 tctaaacgtt ccgacccgaa cttttagaga acaagtttat gaaggcaacg ttattcacaa
    33661 taaaaatacg attctcaccc atgcagtgaa caacgctatt ttaaaaacgg ataacaacgg
    33721 cattcagatt aataaatcaa agaacagtaa caaaattgat ccaatagctg cattaatcaa
    33781 tgcctatgtg tttgcaatgg attacttcac cacaacggaa ggagcgaaag cagacaatga
    33841 attttataca agtgaagaat tttctttcta attacattca taccgttctt ttacttcttg
    33901 gattggtgtg tgtgttggtt gctatcacct tactaacaaa tgtctactat ggcttgttag
    33961 cgctgggcat agtgcttatt ggggtagcgg tcatgctaaa tacagaacag aagggaggtt
    34021 aaaagatggc attttttaaa gcgagacaaa atacaacggg agatcctttc ctacaacatg
    34081 tggtatcaat ccaatcggat gattacacca ccagctttac aagcgttcgt gcattaagaa
    34141 atagtgatgt gtttgcagcc gttcgaatta ttgctagtga tattgcttca agtccgattc
    34201 aattggtcaa aaacaatatg ccacaagctg ataatgaact ggtgaagtta ctaaacgaga
    34261 aacctaattc agaaatggat ggttggcatt taaagtttgc tttggcggtc aatatgttgc
    34321 taaacggtaa tagctttgca gagattaaac gcaacggtga aaaggtagaa gaaattcact
    34381 tattacctaa ctcaagtgta acggttactc aattagataa tggtacgttg tcttatcaga
    34441 ttggtgataa aaaaagacgt gtgaagtcta gcgatatttt gcacttcaaa tatttcaccc
    34501 aagatggttt aacaggatta ccaccacttt atgcgttacg tgatgaactg aaaattcaac
    34561 aagctggcaa ccgcacattg cacaatttct ttactcgtgg tgtcagtggg tcaggtattt
    34621 tgaaggttca taagtcagat ttagacggat cagcaaagaa cgcaattcgt gaaaagtttg
    34681 aagaagccaa cggttcaagt agtggagata atgctcttag aacgatcatt cttgatgaaa
    34741 caatggacta caaaacatta gaaataaaca ccgatgtttt gaagcttatc aattccaatg
    34801 attggaacac aaaacaaatt gccaaggcgt ttggtgtacc gattgagcgt ttaggcgttg
    34861 aaaatgaaca ttctagcacc gttcaaagta atctccagta tatccaaagt acgctgattc
    34921 attactttaa tgtgtttgtg agtgaattag atacgaaact tgaaaccaat atccgcttta
    34981 attccgatca gttactagag actgatcctg aaacaaaagt aaaaaatgta ttggatcagg
    35041 tcaaagggtc acttctcacg attaatgagg ggcggtcgaa aatggggcta ccccccatgg
    35101 atggtggcga tcgtttacta gcaagtttga actttacgta tttagatacg ttggagaaat
    35161 atcaattaaa agaacaggaa ggagttacac cagttgaata atgaagaaga aaaggaaaaa
    35221 cggctgacag aagaagctga gctaacagcc gattctccca aagtagagaa agaaaatgaa
    35281 aaacaaccaa cagacggcaa aactatttca ggctatgcgt tgaaattcgg gcaaccgtca
    35341 aaagatttag gcggctttgt agaagtgatt acacccgaag cattaaaaga ggtggattta
    35401 tcaaatgtgt tcttattata tggacacgat tattcaaagc cactagctag tgtcaaagca
    35461 ggtacgttga aattgaatgt cgatgataca ggattacatt ttgaagcaga gctaaccgac
    35521 acgacctatt caaatgatgt gtatgagaat atctcaaaag gggttgttga ttctatgtcc
    35581 tttgggttcg tgcttggatt agattcattc gacaaaaaag aagatggcac aattgaacga
    35641 tcaatagata aaatcaaagc acttaatgaa attagtgtcg tgaccgttcc cgcttatgat
    35701 tcatcaaatg tccaagtaaa taagcgttct tacgaatcgt ttatgagtaa caaccaagca
    35761 aaacaaacaa acaatagctt agaatccact tctaaagcac aaaaggagag taataacatg
    35821 gaaaaaactt taatcgataa cgaaaaaaca gaattgcgtg ggtatgaaga atatatccgt
    35881 tcacaaggcg aagtgcgtga tggagtcact actgtaaatg cagcggcagt tgttcccgaa
    35941 gaagtaatcg gtgaagtctt tgatttgaaa cgttcaaatt ataacttagc tcaatatgca
    36001 acagtaaaaa cagtatcaaa tggacaaggt aaatatccag tagcaactaa ccaacaagca
    36061 gtgttagcaa caaaagctga acttgctgaa attggtgata ttgacgctga aatgtttact
    36121 tcagttgatt ataaagtaga aactcgtgct ggtaagattg ccttatcaaa tgaggttgtg
    36181 gaagattcag cagtgaatat tgtacaagag gtcaaagatc agttagcgaa attggtagaa
    36241 aacactgaca ataagcatat catggattta ttaaaaacat tcactaagaa aacggctgct
    36301 acgttggacg atttgaaaca actatacaat gtggcattag acccagcatt aaataaaatg
    36361 gtaattctaa accaaagcgg atattaccac ctagatacat tgaaagattc agatggacgt
    36421 tacattttac aacccgatgt gacagcacct agtggtaaat cattattcgg tatgccagta
    36481 gtattgattg cagatacatt gtttgccaat cctaaagctg gaacattccc tatgattatg
    36541 ggggatattg cacaatctat ctttgttgct cgtagaaatc aagtaacgac tcaatgggaa
    36601 aaattcgatt actactcaca aggacttgca gtgatcgttc gcaacgatta taagaaaatt
    36661 gatcaaaatg cttcagtgta tattgagttt acgccagttg taacaccaaa agtatagaaa
    36721 aatattgggc ggcggtttat cccactgcct ttttttcatt aggagagata aaatggtaat
    36781 tttggatagc ataaaaaaaa gtatgcggat cgatcacact attgatgatg actttattca
    36841 acaattgatt gatacagcag gcgaatatat aaaaagtgct attgatagta gcgcaacgga
    36901 taaagatatg gataattatc agcaatttga tttggcggtg tcattactta ctcaacattg
    36961 gtatttgaac cgtcaagaag ccagcagcga acggatacca gtaacggtac aagcattagt
    37021 acaacaaatg agaggtgctt attatgccaa tcattaagaa tgtaaatgaa ttgactgaga
    37081 gagtcaagtt taaaaagaca aaacgggtaa aagatgaaga tgggcagatg gtggatagtg
    37141 aagaaactgt atttgaatgt tgggctaatg tgcgttcaca aatgctaaaa gacgtgcttg
    37201 ctagtgtagg taccattctt gaaggaacgt tgacgtttat tattcgatac gatcaagatt
    37261 atgaactaac aaacgatatg aaagtagctt ggaaaaacaa gagttataaa attatttcaa
    37321 tcaatgaagg aacggcgttt aaagattata caacgatcat agctaaacag atttcttaga
    37381 atgattacac ttgtaaacgt tgtgggtatt tagtataatt aaggtagtaa atgaagggtt
    37441 agctgcctga attttgcaag acttagctag tcgaaatcta ttgttggact gaaaattgta
    37501 ggtgtggttg caaacatgct ggactaagaa agatgataga tgatgaacgt tcaattttaa
    37561 tacaggcatg ctaggactga ttggatggtt ttggcaagct gattgtgtag aaatcaaaga
    37621 acacgtctgt tgtggacgtg ttttttttgt tataattcaa aagaggtgat ttaatggaca
    37681 aagcagagtt tacaaatttt tattggaagt attatctaca tttagaaaat gagtttatta
    37741 ataccacaga ttttgtgatg ctcgatgaga ataatttcaa aacattctct attgaatatc
    37801 aaaaactact actagcgatt ggttcggagt gtgagattat tttcaaagaa ctttgcggat
    37861 ttgatagcag tagcaataaa agcataactg attttaaagc tgttattaaa tctagcgaat
    37921 taatgtgttt ggataatggt gttagggtta tgaattcttt aacattgact tcactaaaac
    37981 cttttggaga tgggtggcct gaagatacac cagattggtg gaaaatatat aacagagtaa
    38041 aacatggtcg ttcttcaaat tataaggaag caaatttgga aaatgtgttg tatgctttag
    38101 caagtctata tttattagag gaatatttgc ataagaaagt aatactagaa ggtgaagtag
    38161 actttataag tccagagtca aatctattta cgttatcttg ggaaagaaaa cattcgtcga
    38221 tgcaaaaagt gacgtttgaa aaagtggatt caaattatgt agctccactc attgatttta
    38281 aagaacaaga agaaatttaa aaacccccac ggcttattga agtttttgta tgccatattg
    38341 tatgccattt ggtttaaatc gcttgaaaaa tagtgataga taactctaat tcatttagtc
    38401 ataaacgctg ttttgataac ctttatagtt ctttgatatg ggtttctcat tcatggcgga
    38461 agaagaagaa tagaacaaaa gaatgaatta ataagatata aaaaaaggga ttgtgacaaa
    38521 cgtcttgtca caatcccttt ttccaaataa acgatgttca atcagctgcc cctcggcatt
    38581 cgctcgaaaa acggcgaaat atgaagaact attttgccat ttgtttctct aataatcagg
    38641 tcaaaacgtt gacttcacag tctcttcctt aaacggtgtt ctcctgccaa ctcctcggtc
    38701 acaagtcaca atattcaaca aacatgagaa gctgtttttt gaaattgttc cttgtgactc
    38761 ggagctgaac ggcaggctca cgacctcttt cttaaacggt gttcaaaagc ttgcatctgc
    38821 ggtaataagt tcaaccaaac gaaaattatg aggagctatt tttgtttggc tgttcttatt
    38881 acttgatgca ggacagcttt ttcacaacct cttttcgttt agcactaaat ttccttaaaa
    38941 agtagaaaag ctttcgaagc ctcgtttgtt tcttttactg tataataaaa gaaaagagta
    39001 acaatcgcta aaagatataa acaagagaaa ggaaatacaa gatgattggt ctgatttatt
    39061 ttgtggtgat cgttctggcg aacacagttg gcgctatttc cgggatgggt ggaggcgtgt
    39121 tgatcaaacc gattcttgat cttatcggcg cccattctgt tgcagggatt tctttttact
    39181 caacagttgc ggtattcacg atgtccattg tttcgactgt gcgacaagta tcaagcggga
    39241 aatcactgaa ttggcagatt gtcggttggg tatctagtgg agctgttgtt ggaggagtag
    39301 tcggcaacat tgtattcgaa gtttttttac agttatttga aaacgagaag catgtgcagc
    39361 tgatccaaat ttttttgacg gtattgacct tggtttttgc gttcttctac accaagcatc
    39421 atcagccaaa atttcatttg acgtcatgga cttggtacct tatatgtggg ggggttctgg
    39481 gctttttagc tagtttttta ggtattggtg gtggaccagt caatgtttct ttgttgatgc
    39541 tgatgtttgc attgccaata aaagaagcaa cactatattc tctatctacg attttctttt
    39601 ctcaactggc aaaattggta acgattgctt taacaagtag ctttatgcgc tttgatttat
    39661 ctatgttgtt ttatgttatc cccgctgctg ttattggagg tttgtgggga gcaagattta
    39721 gcagggtttt gtctccaaaa aaagtgacct ttatttttca agtaattgtc ctcgtggttc
    39781 ttttgatcaa tctttacaat gctttcgtca tcttacaaac attaggagaa tctagactaa
    39841 cgcaagtcaa aatcactgaa acatattgtt ctaaatgaaa aaaggagtat actgtgataa
    39901 aaaaattcat ttaaaaaaat aaaaattggc tggtgatttg gatgttgcgg gaaatgcgtt
    39961 taggagatgc agaagcacta cgagaaatca atgcggaaca attaggatat gatgtaccat
    40021 taaccgttac ggtgagacaa atgaagaaac tgttgaagga gccagaaaaa aattttttct
    40081 tggtctatga agatcctact tctaaaaaag cagctggcta tgtacaagcg gagtcctatg
    40141 aatcgatttt cagcgatccg atgttcaata ttatggcact tgctgtgtct aaacatgctg
    40201 aaaaaagagg aatcggaaag gccttgatga ctggcgtaga agaagcgaaa agacgaggaa
    40261 tatcagcaat aagacttaat tctgcagaat acagagtaga agcacaccga ttttatgaac
    40321 gcatcggtta tcattccgat aaaatgcaaa aaagattttt gaaaatcctg taaattttta
    40381 tcaaaaaata cctggtcatc aagccgatac ttgatgatca ggtatttttt ttgactaaga
    40441 aagtaattgc atcaagaaac ctgagatgat caaaacgatg gcaccaccaa gccgattgcc
    40501 catttgagca aaagcaataa gttccatccg attagctgca gataagacag ctacatttcc
    40561 tgtaccaccc atcgagttgt tgcataagcc agcagtaata gttgattcga ttggatataa
    40621 accaaacaaa cgaccgacaa atcctgaaac tactgaaatc gcgataacac ttgtcaaaca
    40681 taagacaaca aattgccatg tcaaagcaga agccaataca tttagattca ataacgcaat
    40741 accgataccg gcaagaacag ctgctgtcaa gtttttgaca atcaagttgt tgaacatgat
    40801 agctgcatct tcgtaatatt ctggtaatag gtttgcgatt ttacagataa caacgataat
    40861 gatcatgaat gcgtaagcat ggactttagg aacaaaatag ttacagattt gtcctaagat
    40921 gaagaaagtc aatgatacca tcaaaccgac acctaattgt ggaatggaag gttttacatt
    40981 tctaggtttt ccatcgccaa ggtcgccttt ttccattaat ttaccattac cgttgaattt
    41041 tggcattgat tgtcccgcac gagcaactaa cgctgcacca atgatagcta ggacatttgt
    41101 cattgctgtc gcaggaatca ggcgggaaat gatagaagaa gcgtccgtac ctaaaacatt
    41161 tgcataaatc gttgataaag gtacagctcc ggctccaaca ccaccagcca ttgcgggcaa
    41221 tgagatatat aaaacggaat ttgcaaaacc atttccgata agcataccta cgagtcctac
    41281 ggcaaaaaag gagacgacca ttgaaataag tgcaacggga ataaaacgaa cagaagcttt
    41341 catcaataga ttacggttca taccaaggat gctaccagta atcaaggcag caatataaaa
    41401 gtctaaaaag cccatattgc tgacaaagtt ttctgtggat tttactacat actcaggtaa
    41461 gatcccaaat gtagcaatcg cggcagaggc aaagatcgca aaaacggagc caccacctaa
    41521 ataacttttg acgataggga tttttgttcc gataaaatga aataaattac cgaaaatgac
    41581 caaaacagcg attgggccaa tcatattcgt cggtaatttt cctaaagcca ttgcaatgat
    41641 caggacaagg accatgatca aataaagggg caaacttacg ccggtaattt ttgttgacca
    41701 aaacccttct tttttctttt cctcaactgc agttgcggtt gttgtttttt gtgccatttt
    41761 tacagatcct ttcttattct gtatcgtatg aaaaaagcca aagagaagcg gcaaaagagc
    41821 agtagttggc tggctgctgt tttgccgcag tcgctttttt ctttttagac gtcatacaaa
    41881 gtttctgtat gttcttttac tataacaatc ttaatcttct aaagatttat attcaggaac
    41941 ccatttagca gattcaacag cttctttgat atccgtgatt tcttcacgat tcaatttttg
    42001 tgcaacaact gattttgcga cagtttcagc aatcgtttga gagaattcag tgatttttgc
    42061 tactggaggc aagatagctg ctcctggttt tgttacatca acgattccgc ctaatgctcg
    42121 actagcttga gaaatgattt cagcatttac tcgtgtagct gttgaagcaa tcaaaccaag
    42181 ccctaaacct gggtacatca acgcattatt tgcttgaccg atttggtaag ttacaccgtt
    42241 atattccaca tcagcagcag ggatacctgt tccaactaaa gcttttccgt ccgtccattc
    42301 aatcaaatct tttgcttttg cttctgccaa ttttgttgga ttagacaaag gcatgatgat
    42361 tggacgtggg gtatgagccg ccatttcttt cacgatttct tcagtgaatg ctccaggttg
    42421 ggtagaagta ccgatcatga tcgttggatg gattgctttt acaactgctt ctaagtttgt
    42481 caattcatca gcattagtga attctgagcg tttacgagcg aatgggattt gaccaggagt
    42541 caatcctttt gtatcttcaa acaataaacc ctgtttatct acttgataga aatgttggcg
    42601 tgcttcttct tcaggtacac cttgacggat catttcatct aaaaggatgt ttgcgatacc
    42661 tacaccagca gtaccagcac caaatgtcaa gatcgtttga tctttcaatt gctcacctga
    42721 tatattcaat ccacctaata caccagctag tacaacgatt cctgtgcctt ggatatcatc
    42781 attgaaagta gtgattttat cttcgtattt ttctaagatc gttgcagcat ttcctcgtcc
    42841 aaaatcttcc caatgtaata acaattctgg gaataattca gtagctgatt gaacgaattg
    42901 atcaatgaat tcgtagtaag tttcgccttc tacacgagca tgacgattcc ctaagtataa
    42961 tggattattc aataattctt cgttattagt accagcgtcg attgatacag gcaagacttg
    43021 tgcaggattg ataccagccg cagcagtgta gaccatcaat ttaccgatag cgatgtcaac
    43081 accgttcaca ccccagtcac ccatacctaa gattccttct gcatctgtca caacgatcaa
    43141 acgaatgtcg cgtccatctg ctgcgttttt caaacttgct ttgatatttt ctggttcgtc
    43201 gattgaaaga aatgcagcat cttgtggttt caagaaaatt tcgttgtatt gttcgattga
    43261 atccgcaacg acaggatcat aaacgacagg catgaattca actaaatgtt cgcccatcaa
    43321 tttataaaac aatgtccggt tcgtattgaa tagattcatt aagaagatac gtttttccaa
    43381 atcggtctgt ttgcttaagt attgaccgta agcttggaca gattgttgtt ccaatgtttg
    43441 gacagtactt ggaagcatac cagtgattcc gtattttgcc cgttcttctt ttgtaaaagc
    43501 tgttccttta tttagaaaag gattatttaa taagtttagc cctgtaagca tgaatgattc
    43561 ctcctaagtt ttaatacaaa cgaagtatag gagtcagatg aggatatagt caaaaagagc
    43621 aggtataata aattttattt atatgagtaa tagagtcaaa agaaatcaaa atagcggtat
    43681 ttgttctttt tatatcaaca atccttgctt gattactatg cgtatctctt atatgctaaa
    43741 gaaagaaaag tagaagaata aaggatatgt tagatagata aatagaatct ctgaagaata
    43801 aatcacgtga tcgtgacgat aaaatacact tacgtcaggt gataaaaaat acataagtag
    43861 aaaactaaga ggaggaacag aaaatgaaag aagttcaatt gatcagaaaa agcgaactat
    43921 cagaaggtgg ttgcaatgca tgcggcgtag tagaagcaac aagctataca ttaaagcttg
    43981 gtgccaacaa agcgataatc tctgagttga cagtaggcgg tcttgtggac agtctggcgc
    44041 ttgctgaagg ttttattgga gaagatattt atgagatgtt ttcagaaatc cgtcagttaa
    44101 aaaaagggga aaactgcata gaggttcatc atgagagccc gaatgtgaga ttcaaacgtg
    44161 gtgataatga gatgatcttc aataatcatg tgtccgatca caccgagcta tatggaatcg
    44221 tgaatcaaat actaactgag ctttttggat tgggacctta tgcgttcaag gaagaaaacg
    44281 gtaatccaaa attaaacgaa gaatggcaag aaacgattga aatacaaaga aacaacccgc
    44341 acttatttca ataggcatcc acagtatttc gtaaaaggga ctttgacacg acttttgtca
    44401 aagtcccatc gttttttatc tatttgtgtt ctaaacattt ctttcagagt agtaacaact
    44461 ggaatgactg aaatgtaaac agattatttg cctgtatcaa tacggaagag taatataaag
    44521 tgtgtaaacg ctatcatatt attcattcaa ttttttatag agggaaggca ttgaaatgga
    44581 aaaaacgtat caagcaggta caaatgaagg aatagtggat tttatcaata tggaagattt
    44641 agaaatagcc gcttcacaag tgattccagc tggtggttat ggttacatca gcagtggtgc
    44701 tggcgactta tttacttatc aagaaaatga acgggcattc aatcatcagc tgattattcc
    44761 tcatgtatta aaagatgtag aattacccga tacaactaca cattttgaca aagaaacgct
    44821 gactgcacca atcatcatgg caccagttgc tgctcatggc ttagctcatg tgaaggcgga
    44881 gaaagcttct gcaaaaggtg tagcagattt tgggacgatc tatacagcaa gttcttacgc
    44941 ttcttgtaca ttagaagaga taagagaagc aggcggggag aaagcaccgc aatggtttca
    45001 attttatatg agcaaagatg atgggatcaa tttggatatt cttgaagtgg ccaagcgtaa
    45061 tggagcaaaa gcaatcgtat tgacagcgga tgcaacagtt ggcggaaacc gtgaaacaga
    45121 ccgcagaaat gggtttacct tcccactgcc aatgccgatc gttcaggctt atcaatcagg
    45181 agtaggccaa acgatggatg ctgtgtacaa atcttccaaa cagaagctta gtccaaaaga
    45241 tgtagaattt attgctgctc attctgattt gccagtctat gtgaaaggtg tccagtcaga
    45301 agaagatgtc tatcgttcat tagaatctgg tgctggcgga atctgggtat ctaatcatgg
    45361 tggccgtcaa ctagatggtg gtccagcagc gtttgattcg ttgcaatatg tggcagaagc
    45421 agtagataaa cgtgtaccaa tcgtgtttga cagcggtgta cgacgcggac agcatgtttt
    45481 caaagcaatc gcatcaggtg cagatcttgt tgctattggc agacccgtta tttatggatt
    45541 gtctttagga ggaagtacag gagtccatca agtgtttgat ttctttaaaa cagaattgga
    45601 aatggtcatg caattagctg gaacacaaac agtagaagat atcaaaaaaa taaaattgcg
    45661 tgagaatcgt tttatttaag aaacaaatga cgaaaaaaat aggagtgcgg cagatgatgc
    45721 cgtactccta tttttatagt tcaaggatgt cactaataga ataatttgaa acgaaaaaat
    45781 aaaattgaaa tattttttca tacttaataa aaaaggaaga atattcatgt aaacgatttt
    45841 attgtttttt tctcttttat acaaaaaggg tcataatttc aagtaagcgg atgaattcat
    45901 gaggattttt tgcatactgt ctctactata cttaggtcac taagaaaaag gagtgattta
    45961 ttatgaaaaa gaacatgatt gggacattat tactttcaac acttcttcta ggcggcttgg
    46021 caacaccagc ttttgctgag ggtcaagcga cttcaaaagg agatattacc tttactgaac
    46081 caacaaatac cgtggagcct cttaacccta ctgatccttc aaaaccagta gagccagcag
    46141 atccggaaaa tccagcaact ggccagacag gtcctttaac actggatgta gttcccgaat
    46201 tgccatttgg tacacacgag attgaaagcg gaacaaaaac gtatcaagta gacgcttcaa
    46261 aaaacgatac accttatctc caagtatcag atcgtcgagg tgtaggtgca gatggccaag
    46321 cacaagggtg gaacgtgaca gtttcggttt cagattttgt aaacggttca caagttttgc
    46381 aaggcgctga attagatttt ggaacatcca ctgttaaaag tacgtcagat aacgaatcca
    46441 ctggaccaac tagtcaaact gtaactgggt tgagtaaagc aagtgcagcg acaccaatat
    46501 ttacagcagc aaaagatcaa ggtctgggaa catggctttc tgtttatgat ccagcaaata
    46561 tcacactgaa agtgccgaaa gcagcagctg gaacattcac ggctgatttg acttggaacc
    46621 tcgtggctgg cccagtagca tagagtatga aataaattca acaaactgcg gtgaaaatac
    46681 tataggtgaa ggatttttta ccgcagtttt tgttgaaagg atgtggtgga caatgaatca
    46741 aagtaaacga ctgtttgttt cgtttttttc tattttaagt ctatttttca tttttccgtc
    46801 aatcagccaa gcaaaggatt cagcaggaga ctttggaatc aaaccggtat ttccagagaa
    46861 ccaaatagat aaagcaatcg gttattttga tttattagtg gcaccggaac aaaatcagac
    46921 actagaagta attatcagca attcttcaga tgaagaacga acatttgagg tctctgtcaa
    46981 tccggcggta acgagtgatg gtggaacgat cgattatagt caaaaaaacc caacgttaga
    47041 tgagacattg ccgtttgatg tccgtgacgt tttgctcatt gcgaaaaagg aaatcaatgt
    47101 atcagcacat gcagaaacaa ctgtacctat agaagtgaaa atcccagcaa aaagctttaa
    47161 gggacgtgta ttagcgggta ttcatgtttc acctaaagaa gaagctgaaa cagaaaatgc
    47221 tacagaagga gcacaaatca aaaatcgtat tgcttataat ctcgcagtcg ttttacaaga
    47281 aagtcaagag acgatagaac cggatctgaa acttttatca ggagatttgg acgaggtcaa
    47341 cgcaaagcca actgttcagc ttcgtttcca aaatcctcag cctaggatta tcagcaattt
    47401 gatatttacg agcaagatct tttatgaaaa tcagctttat attgaaaata cgtctaatgc
    47461 atttttagtt gcaccaaatt cgaattttca cttgaatctt gatttagctg gtgataaagc
    47521 aaaagccggc gattaccgcg cagaaatcat agcaaaatca ggcgacagta atgaatggcg
    47581 atttacacaa aactttacga tcaaaaaaga aaaagcacaa aaagtaaatg aaaattccgt
    47641 ttttgcagta caagaacaat ctttcccatg gctttatgca ggattggttg ctgcagttct
    47701 agtgttatgg ttgattttgc tgtttttgtg ggtccacaag aaaaagaaaa aaggagaaac
    47761 aacatgatga ggtgatttcg ttgaaaacat cgatcttatt gggagggatt attgcaagtt
    47821 tgctgttctt cagctggcaa gagccagtcc aagcagatac caaaagttca ggtacgatta
    47881 cattttatga tctaagtcca attccgcatc caagtggttc agtcaatggc gcatcaaaac
    47941 agcagacaca gctaccgatt tataaagaat ctaatcaaca tggcgtattc ccggagacga
    48001 atgaacaaaa gatccgtttt ctttatttga tcattggtat agaattatgg cttcttgcgt
    48061 ggttgttgtt atggagaaga aaggaaaagg aggatgaaca tgttgctaca aaataaattt
    48121 tcattttttc gctccttctt ttttacttcg ctttttgttt taagtatatt tatcttttca
    48181 ccttcggcag aagctgttgg agcaacgcct cctgccattt cttatgatcc atacacgtat
    48241 gaaaatatcg tacctccaaa tggtggacgt agtgcagtca atggcgggaa gcttgtccaa
    48301 ctaactgggg ctaaccaatt gcctaaattg actgctactt atttgaacga tggttcaaat
    48361 gatccttgga aaggtggcac ggtccgtttt cattgggaaa gccatgtgaa actaacaaat
    48421 gtacttgatt tggtgaatat cactgcacaa ggatttgcat ttgtggcgat catcaatttg
    48481 ccggaacatg tatcaagcag tgatgtatta aaagcaattg actggaacaa cgcctacttg
    48541 tatattgccg gtgcccccat caaggttact agcggaagtt tattatcagc aggaagccat
    48601 accttgcgtt ttgggatggg gtcgtgggat acaaatactc tattgacaga tattattgct
    48661 attattacgc gaggcgaatt caacgtggac gatatcccgc ttcaatttga tgttacagct
    48721 aatgtcgcga agatgacaga aaacggagat aaatatgata cgagtccaaa caaaattttg
    48781 accaagggta aattacaacc ttctatgtct aaaaaggccg ttttttctgt tgatttttat
    48841 gattcgaata atattatcca agatcgtatg ttcaattcga ttttagctcc agctgcaggt
    48901 agattttatc ctaaattaac tggcggaaac ttgaatccag gagcatatgc attttctgca
    48961 agtgcagaga taaatacgtg gaatagttac atctcaccaa gtgattcaac aggaaaatat
    49021 aatacatttg ctgataccac agaatacgtg gatggaaata accagaacct tccaggctct
    49081 accaatagtc ggacattgac gatggggctg actgaaggac gttttgatca gttgccattt
    49141 agtcgctttg atcgcgtagt caactatttt acaggaaaaa acgttacaca aggagcaata
    49201 ctgactcata ctccagcaag cacaagtgga ttgaatcaga cagccaatat cgtgtacagt
    49261 gggaaagatg cgcaaggcgg attgctttct cctgttgctt taaaggtatt ggagcagtac
    49321 aagctagacg gaacggtttt accaacaaac ttaacagccg atagtcagtg gggaaagctc
    49381 ctttcttctg catcgtacca agtcacggcc aattggtcag caactgaact aaaaaagggt
    49441 tcgatccatt acaggcttta ttcgaaagga acccaaaaat tagcgacagg atggacagat
    49501 caacttttcc aaacgatcca atcaaataac gggggtgtaa atacagctac ttctacacta
    49561 cctgcattgg cttcagggca atattatttt gattatcgct tggtggacga tgtacttact
    49621 aacatgtatc cgtcttttgc gtacaaatgg cagtctgaac aagctggaat caccactctt
    49681 cctcaaataa cagtggctaa ttttccatct gtgagtgcag atagtcagct aaaaaacctt
    49741 agcagacaac ctgagacagg agatcccctg tctgctctat caggagatac gattcaagaa
    49801 aatgtgacat tcacgttaac aaaatctggg gatgcgataa ccgacaaaaa aatcacgatc
    49861 tcacttcctg aaaatactac ttatatcaat ggttccttaa aattaaatgg tacaactatc
    49921 gcagataccg gcattcaaca aggagtttct gtcccagcag atctattgag caaaatagga
    49981 gataccattc atcttactta caactatcaa ttaaatactg tagatacttc tttacaatcc
    50041 gtcagcatac tgacaaaggc agctgtactt tccagcaata ttacattagc agatggtgct
    50101 aagcttccta acccagttgt ccaaacatct gctaaaacaa ttcttgtccc caaacaagaa
    50161 ttaacattag ttaatgtacc agatgatttt acatttggta acgatctccc caaaccgttg
    50221 aagacaagtt attatgaatc aaaaggcgat ttttcttttg atgtgcggga tactcggctt
    50281 ccaagcacgt ctccttggca actgacaggt acattgactt ctttatttaa gaatgatcaa
    50341 ggtcaagaat taagcggaac aaaattatac ttcaatcatt ctggatcaaa gcaattgatt
    50401 cagcaaggtc aaaacacgtt gatttatgag agtgatggaa cagctaaagg agaggttctc
    50461 gttgactttc ccgataccga tggtttactc ttagaggtaa atagcagtac gaatgctcaa
    50521 cctggcgcaa cgtatcaagg catggtcaca tggaaactga cagctgggcc aaccagctaa
    50581 gtgattagaa tttgtatgga tctgtgataa ctgtcacaga tcctcttttt caaggatgag
    50641 aaggaaactt ctgctgttaa aatcagaaat gcttgaagga gtggacttgg aacttttcag
    50701 tttgcttgaa aaaaatgaac aacggcaaat caaacttttc caacttttat tagaggaaaa
    50761 aggagaggtt tccgttaata acgtacttac ccgcttatca gttgatcggg ctaccttgaa
    50821 agaagatctg ttttatttac aagctaactt ggaaaatatc aaacaattgg aaattgttat
    50881 ccaagaaggg aatattttat taatcagaca tggaaatata gcagcagtcg atgtttatta
    50941 tcattgttac ttgcgctatt ctacaaaata tcagatactt ctttatctgt tggaaaatgg
    51001 ctcatttgat cggcagaaac ttgtcatgga acttaatatc agttcggcta ctttgtctcg
    51061 cagagtgaag gaattaaatg attctttaaa tgagtttcat ctgaaaataa aaagcgggcg
    51121 gctgaccggt ccagaaagtc aaattcgtta tttttatttc caattatttt ggtttggacg
    51181 tccctatctt gaaaacaaaa aagaatacag tgatttatca ggaaacactt ttttagatct
    51241 gctgcaaaaa gagtttagtt ttgctattac agaagaagga cgattgaaat ttgaaatatg
    51301 gctttccatt atgaagaagc gaatgcgctg tacgaaaaaa tccaaaccag attatagcaa
    51361 tcttcctgtt ggattgtttc aaacgacaca atttttattg gacctccata catttttgac
    51421 ccgttacttc tttcaatatg cctttccttg gaatcaaaat gaaacgttgg ttttttatct
    51481 tttcatgatc agtaacttta cattagatac acataactcg catgtccagg agtttttgat
    51541 aagcgaaaaa tacaaagacg acgtagtagc tcaattgaat cgaacgttta aacaatcgat
    51601 agaagaatat ttctcttttt atgtttttcc agaagagatt tcgcaaaaga ttgcgttgac
    51661 agtgatgcaa aatcacgctc attttgccta ttttagagga tggatgaata tttttggcca
    51721 agaaggatta aaacagcggt taactgaagt agaagataaa caattcctgg ttttatgtga
    51781 aagattggtc agacaaacat ttgctattgt tgattttact gaagtagacg aggaaaatgc
    51841 ccgctttgaa ttatttgctc gctatgcatc tattttacgg acgctgatca agcagttaga
    51901 attacgtctg caaattgctt atgatcttcc ttatgaaagg ctaatggcgg atatcgtgaa
    51961 agaaatcatc caggaacaat tgctgaatac gatcaaatat gatttagtcg aatacgagaa
    52021 agaaaagcag tatgatatca ttttgactag ccaattgaaa gagtacccgt cacagaagtc
    52081 cgctaaagtt tttgtattca ctagcaacga atataattat gatttcccct atttgaacca
    52141 atttttaaaa gaatgttatt tagaaaaatt gaatttaagg atgaataaaa catgaaaatc
    52201 gtgatcattg gtgcttccca tgcaggcatc acagctgccc taaatctaag aaaacttcaa
    52261 ccgaaagcag aagttttact gatcgatgaa gatcataaag atggactagg ctatgtttca
    52321 aatggaatca acctttattt aaaaggaaag atacgtagtt tagctgaagt tgcccataac
    52381 atgcggactc ttcaagaaag tggggcaaaa ctgatcaccg aatggagagt aactgaactt
    52441 gatccagaca aacatcagct catcctcgca tccaaagaag gaaaaaacga gaccataacc
    52501 tatgataaat taatcgtagc gacaggttcc tctcctgtca ccttgtataa acaaattgaa
    52561 gctgaaaatg tctacaccta taaaaatcta gtgcaatcta agcaagtact tgccgcttta
    52621 aaagaagcaa aagaagtagt gatcttcggt gctggttaca ttggattgga attagcagat
    52681 gctttgagaa ataaaggata cattattcat ctagttgatt atatgccgaa tgttttatca
    52741 agatatttcg ataaggatat gatcaacagt tttcaaaatc agctgcaaac taagcaaata
    52801 aatttttatc caaatgaatt cttgatcgat tggaaaaaat cagaagagaa agtagtatcc
    52861 gtacaacttc tgtctcaaac aataaaggca gatatggtca ttttttctgc ccaaactcgt
    52921 cctaatacga cattgttaaa agaaaaagtg gctttgtatg aggatgagac tgtgatagtc
    52981 aatgaatatc tgcagacaag tgatccggac atctatgcga ttggagatat cgtcccagtc
    53041 agttttgaca aaaataaacg gcatctcttt ttacctttag ttactcgagc tgtacatatg
    53101 gcaagagcag tagcgctaac tttgagtggt cagccaaccg cttacgacct cagacaaaag
    53161 ataacagcag cagtcattat agactacttt ttaggaactg tagggctgac agaagatgaa
    53221 gcgccattct tggaacaaaa taccggttcg tgttcaggag aatttgatct atttccacaa
    53281 tacgacgaag aaaacaaaac agtaaatgca aagctgatct accatccgga tacattagaa
    53341 ataattggcg gacagctgat aagccaagaa ttcttattat cagatttgaa cctgcttgcg
    53401 gatatcgtga aacacaaaac tacgattcca cagctagcag ttgaggattt tggatttctg
    53461 tctgaataca cctctcgttt tcactacctc aatgagttag cttttaaagt actagctaag
    53521 agagcaaata gcaatagagt agataaaaga ctgtgagaaa tatcacggtc ttttattgtg
    53581 tggggatata ataaatatta atcaatcgag aataaaaaat tcatataatg aaatagcgga
    53641 agaatttttt gagcataata ttcgccaaaa atttatcaag tgataaaatt gttgtataaa
    53701 atgattattt caggaggagg agttaaatgt ttttagcatt aaatgaaatt atgcattcaa
    53761 agttacgtta tgcgttagtt gcaggggtga tgtttttgat cgcctacctg gtattttttt
    53821 tgactgggtt agcttatggc ttagctcaag ataatcgaac agcagtcgac aagtgggagg
    53881 cagattcgat tgtgctttcg aaagatgcaa attcaaatct agggatgtcc atgattacta
    53941 agaagatagc agaagaagtc gaaggtggga aagtggcgta tcttgcccaa acacctggag
    54001 tcgtgactag taaagacagt acagaagaag gaaaaatcaa tgttagcttc ttcggtatcg
    54061 ataaaaatca attcatcatg cccaatcttg ttgaaggaaa agcttttgat aacgatgatg
    54121 aggcagtagg cgatattagt ttgaaagaag aatatggtct agccatagga gatacagtta
    54181 agttatctgg tagtgacaag acgtttaaac taactggctt tacggatcat gccaaattca
    54241 atgtctcacc agttctctat acaaccatca atgcttacca agaaatccgc ttcgaaaaag
    54301 aagatacaag tgaaaatgca cggattaacg caatagttgt cagaggtaaa atcagtaatt
    54361 tacctgaaga tttagaacag atcaaaattt ctaaattcat caatgaatta cctggatata
    54421 atgcgcaagt attgactttt ggatttatga tcggattttt gatcgttatt gcggctattg
    54481 tgatcgggat tttcatttat gtactgacga tgcaaaagat taatatcttt ggtgtaatga
    54541 aagcacaagg gatcacagga ggatttattg cgcgttctgt agtggcacaa acattcattt
    54601 tatcatttgt tggtattctt cttggtctat taggaacagt gggaacatcc cttgttctac
    54661 ctgatgcggt tccattccaa agcaattggc tgttttttgg cgtcattagc ttgttgatgt
    54721 tagtagtagc tgtgttaggc gcactatttt ctgttcggac aatcgtaaaa atcgatccgt
    54781 tgaaggcaat tggataagaa ggaggaagaa catgaaagca atagaattta aagaagtaga
    54841 aaaaagtttc caagatggcg accaagtagt taaagcattg aaagaaacaa ccatgagtat
    54901 cgataaaggg gaatttgttg caatcatcgg tccttctggt tcaggtaaaa gtactttttt
    54961 gactttggca ggcggattgc agacgcctag cagtggctct gtatttatca atgatcaaga
    55021 attcagtaat caaaaagaaa gcgaacgcgt taaactacgt tttaaagaaa ttggctttat
    55081 tttgcaagct tccaatctgg ttccttttct gacagtaaaa aagcagttat tattagtaga
    55141 taagattaaa catgaacatc gtcaaaaaga agcaaacgaa ttatttgagc agcttggcgt
    55201 ggataagttg atcaacaagt atccagaaga actatctggt ggagaacggc aaagggtcgc
    55261 aatcgctcgt gcattgtaca atgatccgtc cattattcta gcagatgaac caactgctag
    55321 tttggattca gaaaaggcac gagaagtagt cgatatcttg gcaaaagaat caaaagacaa
    55381 aaataaagca acgatcatgg ttactcacga tacacggctg attgacaaat gcgatagaat
    55441 atttatgatg gaagatggtg tattgaaaga aaaagaataa ccaaaaagca ggtggaaaaa
    55501 tggtccatcg atacaacaaa gatacacagc aaaaaatttt gaaagaagcg actgacttgt
    55561 ttatgtccaa gggatatctc ggcacttcaa caagagaaat cgcacaaaaa gttgggatca
    55621 cccagcccaa tctctatcat tatttcggtg ataaagaaaa actatatacg gcagttttag
    55681 aaaaccactt aaaagatgtt ggaaaagctt tgagagaaat cgttcaaaca agcgaaacgg
    55741 gatttcaagt aaccttgaca aaaatggcgc agtttttgat tgagacacat ctggtcgatt
    55801 tgtttctgat gcttcacgat cttgaaagca atctttcaaa ggaaacaaga gatcatcttt
    55861 tctttctatg gaagaaaaat tatcgtgaac cttttgaaga aatcttttca gcaaaccaat
    55921 ctgtgctaag aaatgggatt tcaaaagaaa tcgcagcaag gcattttttc ttagtgttag
    55981 caccttacat cactcggtcg aaaagacctg tggaagaacc gctaaatgtg gcgcaattga
    56041 tcgatttata tttgaatggt gtattaggag aagcgtaaag ctgttatata gggagaaaat
    56101 agttaggtga agaagcaaga tatgacgaag atcgttatat cttgcttctt tatataggta
    56161 gtttttcata aagacaaatt tgttattctc tcatgattat cagggtatat ttttatttat
    56221 tatgtcggtg ttccaggaag tgttttaatt taataacgaa gaaattaatt gtttgtagaa
    56281 tgaaggaaac tatttattgg gtagatgaat caccacgaat agtcaaaagg agatttcagg
    56341 atatgccaaa aatgaaaaaa atcattttag cagtaatgtt attttctacg gttatatctt
    56401 ttacagcccc ttttttgctt acttaagctg attttaagtt ttggccctta gtctggatct
    56461 acgaggtgag agtcaagaat gaaaaaaata attggagctt ttgtatttgc aatcattatc
    56521 attattatct gttttcaaat agatgttttt ggtcaaaaaa agatagttgg acaaacggtc
    56581 agcagtacga acagtacggt tacaaagaca aaggaatcat ttgatgatac agaacaagag
    56641 acattaatca aaatcggaaa aaatgaccgt acactatata cagatgactc gctaactacc
    56701 ccacttgcaa ctataaacgg cggagagctg gcggagtttc tttctgaaac aaaaaatgct
    56761 tatcagatca agacaaatga tggctatact ggatatttag ccctcgaaga tggaaccaaa
    56821 gtcacaaaga atatacaaac aaaaccggaa gagctatctg atgcagtgat tgtattagat
    56881 cctgggcatg gcggaaatga tactggggca ttaagcaatg atgaacaaac agaagaaaaa
    56941 gatataacat taagtacagc cataaaagta aaaaaggcgc tagaggatgc tggagcaacg
    57001 gtttatttga cccatactac agatgaatta gtacagcttg gagatatatg cgactacagt
    57061 gaagaaaaaa aggcagatgt ctttatcagt ttacacgcag actctacgga atatgcgaat
    57121 gaagcaactg gaatcacgac atattattac tatggacaag aggaaacatt agcacagaca
    57181 attgctgact ccttcactga tctgcctctg gattcaagag gaatctccac tgggaactat
    57241 caagttcttc gagaaaatct tcaaccttct attttaatcg agatgggtta tatgaataat
    57301 gatagtgatt taaaggaatt agtaacagac agttatcagc agcagattgc tgcaagtttg
    57361 acacaagcat tgaccactta ttttcagtaa taaataagcc cagccaaaca aaaatagctc
    57421 ctcatatttt tcgtttggcc gggcttatta tcgcagatgc aagcttttga acaccgttta
    57481 tttttttagt agcttcaaag ctttttctgt atttgcaaag tgaagtttgg catatttttc
    57541 aagcataggc atgccgcctt tctccaatag ttttgccgct acttggtcag atttcgttcc
    57601 agctcctgat ggaagggtga ttccagcttc agctgatgct ttgtgtaact cttccaaaaa
    57661 gctggcacga ctgatgatag aagcagcagc aacagctaaa tgatattgtt ctcctttagt
    57721 aacgaagtac agtttttctt gtaattgatt tttttctaaa cgcgcatatt ttttaaaatt
    57781 tgcttccggc gtaaactgat cgatcaaaat cgcttctggt ttttctggct cgattttttt
    57841 tagcagcaaa tggatcgctt gattgtgcaa agcgactttc atccgaacgg cattgtattt
    57901 tggttggatc tcattgtatt tttctggaga taagacaagc agtttatagg ggatggtttt
    57961 ttttaagatg tcagcaagct ggatgatttg gctatctttt aactcttttg aatctctaac
    58021 accaagttta cgtaattctg caagctgatc acgtttcaca taagcagcac atactgttag
    58081 cggaccgaaa tagctgccat ttccgacctc atcactacct aaaacggata attgactgat
    58141 attttttggc aaagaagagg ctgtttttgc tggcttggct tgtttatcct gtgcctcccc
    58201 ccatttatca gcttctattg ctgcattcgt accttgaaac atcacttttc cggatgtata
    58261 agcggtaatg gtcgtcccgt ctttttttgc agcaaagcta gtataaggaa tctgtttatt
    58321 taacaaataa gagcgatagt atgctttcat ttgactaagt tggtcgtttg ttgctttgat
    58381 aatgacgttg ctcataaaat tctcctcgtt tttatacata aaactatacc gcaactcacg
    58441 acttttcgtt ttctaagaga ttgcgagaca tagcattttt ttaaagttta tcatataata
    58501 gttaagtatg tgaaaaatat ttgtggagaa cggtgaaaga accaacttca tggtacacta
    58561 aataaaactt tcatcaaata ggaggaaatg attcgtatgg cgcacgaaaa aacacgctac
    58621 aaagcggtga ttgccaacca aacatatact attatcggac gggaaaccaa gcatcatatg
    58681 gatatcgtaa cgaagctgat caatgaacag ttagcagaat tgaaacaatt atcaccacaa
    58741 atggataatg aacaagcagc aatcttgatg gctgtcaatg cgctttcgga tcaattgaag
    58801 aaacaagaaa gaatcttgga gctggaagaa gaaacagcag aattaaagaa aaaaatgatc
    58861 aaatttacag agcttgaaaa tcgtgtgaaa cgcattgaag caatcgagaa cgaagctcgg
    58921 gaagtattga aagaaaatgg tcaagcagat cataccatta aaaatcatgt ggaagcacaa
    58981 cagattttaa acgagaaacg aaaaggacaa attaaacaaa aatcttctaa ttaagatcct
    59041 tttatcaaaa taagaaaaat ttaaaaaaag ttagaagaga aaggaacgta gcatgctgag
    59101 tttgctgatt ttatttttat tgctaattgc gtttttttct ggagcacgtc gcgggtttgc
    59161 tttgcaaatc atattcgcga ttggatatgt attgtcattt attgctgccc agcattttta
    59221 caaaccatta gcaagtcatt tggaattata cattccatac ccagctgtca cgccaacatc
    59281 aaagttagca ttttttgatc aggtatttgc ctttcaccta gatgaagctt tttatgcagg
    59341 aactgctttt ctgattattt tgctaattgg ctggctgctt acccgatttg tgggggtttt
    59401 tgtccatgga ttgacgtatg tgccgatctt gagacaggta gactggattg caggaggcat
    59461 cctgtcacta atcatggctt acgttactat atttttgatt ttgcagttac ttgcctttgt
    59521 tccattagat gtggtccaaa atcaattcgg cgagcatagt ttcgctcgct ttatcgttga
    59581 gagaacgcca tttcttacca acaagatgta tgagctttgg gtaacgaata ttttgaatta
    59641 aggaaaatag tgctggaaaa tatttcgttt tttgtacaga gtagattatt taagaaggct
    59701 gcgtagcgta tgtccggcac agctcttttt tcatagtgaa agataaggtg ataaaatgaa
    59761 taaccgaatc cttgaaacat tggaatttga aaaagtcaaa cagatggtca gacaatttgt
    59821 agtgactgca caaggaaaag aagaactggc agaattggta ccagtgagcg aggaacaaac
    59881 gatcacaaac tggcttcaag aaactgagga tggattgaaa gtgcaacgtc tgcgaggcgg
    59941 gatccctata cctaaacttg aaaatatccg tccccatatg aaacggattg agatcggagc
    60001 agacttgaat ggagtggagc ttgcacaagt ttccagagta ttgtctacga caagcgaatt
    60061 gaatcgtttc attgatgatc tttatgacag tgaaatcgaa tttgcacgtt tgtatatgtg
    60121 ggcagatcag ttagtcacga tccctgtttt gagccgccgt ttaaaggaag caatcgatga
    60181 agacggacgc gtgactgatg acgcttctcc tgagttaaag agcataagac agaacattcg
    60241 gcgaagtgaa caagctgttc gtgaacagtt agatgggatc gtccgtggga aaaatgcaaa
    60301 gtatttaagt gatgcgatca tcaccatgcg aaatgaccgc tacgttatcc cagtcaaaca
    60361 agaataccgc ggtgtatttg gcggtgtagt ccacgatcaa agtgcttcag gacagacttt
    60421 atttattgaa ccaaaacaag tggtggattt gaataatcgt ttgcgtcaat accaaatcgc
    60481 tgaacgaaat gagattcaac gtattttaag tgaactttct gctgaacttg ttccccatcg
    60541 tcaagaaatc atccacaatg cttatgtgat tggtaaaatg gatctgatga atgcaaaagc
    60601 acgatttggt aaagaagtaa aagctatcgt gccgggaatc agtgaagaca atcatgtcgt
    60661 cttgaaacaa gcaagacatc cactgatcga tcaggaaaaa gtagtttcta atgacatcac
    60721 aatcggaaaa gactatcaag ccatcgtcat tacaggacct aacacaggtg ggaaaacgat
    60781 cacgttgaag actttaggtc tgttacaact gatggggcaa gcaggattac cgattcctgc
    60841 aggtgaagaa agtcaaatcg gtatttttga ggaagtattt gcggatatag gagacgaaca
    60901 gtcgattgag caaagtctat cgaccttttc ttctcatatg acgaacactg tagatatttt
    60961 atcaaaagtc aatgaaaaaa gtctggtatt atttgacgag ctcggtgcag gaacagatcc
    61021 gcaagaaggt gctgctctag caatcgcaat cttagatgat cttggtaaaa agtctgctta
    61081 tgtgatggca acaacgcatt atcctgaatt gaaagtttat ggatataatc gggcaaatac
    61141 gattaatgcc agcatggagt ttgatgtgga tacattaagt ccaacgtatc gtttgctgat
    61201 tggcgttcct ggacgaagca atgcgtttga aatctctagc cgattaggtc ttgatacaga
    61261 agttattgat gaagcgaagc agttgatgaa tgatgagagc caagatttaa acgaaatgat
    61321 cacagattta gagaatcgcc ggaaaatggc agagaccgaa tatctggaaa tgcgtcattt
    61381 tgtttctgag gcacaagaac ttcacgatga tttgaaagaa gcttacagct atttctttga
    61441 agaacgtgaa aaagaaatgg aaaaagcaaa gaaaaaagca aatgaagtcg tgtcagaggc
    61501 ggaagaaaaa gcagaaaaaa tcattgctga tattcgtaaa atgcaacagc agattgggca
    61561 aggaaatgtg aaagagcatc agttgatcga tgcaaagacc caattagcaa atctacatca
    61621 agaagaaact ttgaagaaaa ataaagtatt gaagaaggcg aaagaacaaa aaacgttgaa
    61681 accgggagac gaagtgttgg ttacgactta cggccaaaga gggacgcttt tacgtaaaaa
    61741 cgggaatcag tggcaagtag aaatcggtat attaaaaatg aatgtgtccg aagacgagct
    61801 gacgcctgtt gctcctcaaa aagagccgac acaacgagtt atccatgctg tacgatctga
    61861 atctagtagt cacgtgccga atcaattgga ccttcgagga aaacgatacg aagaagcgct
    61921 aagtgaggta gatcaatatt tggattctgc cattctagct ggttatcctc aagtgactat
    61981 tgtccacgga aaaggaacag gcgcacttcg caagggaatt actgattatc ttaaaaacca
    62041 tcggagcgtc aaaagctttg agtttgcacc ggcaaaccaa ggcggaaatg gtgcgacaat
    62101 tgttaaattt aagtaaagct tactaaaggt aagcagatgg ttcgctatcc aagtatagaa
    62161 atgctatact agtcatagat tttaaaaatg gaggtctttg atatgtcaca agtaattaca
    62221 gataagacat ttaatgaaga aacagataaa ggacttgtat tgattgattt ttgggcaact
    62281 tggtgtggtc catgtcgtat gcaagcaccg attttggatc agttggaaca agaatatgat
    62341 gaagaagaat tcagaattgc taaaatggat gtggatgaaa atccagaaac tcctcaacaa
    62401 ttcggtatca tgagcattcc aacattaatg ttgaaaaaag atggtcaagt agtagaaaaa
    62461 gctgttggtg ttcattcaaa agaacaacta cgtcaaatga tcgatcaata tttataaaaa
    62521 cttacagcaa aaataagctg agggtgggac tgaatccagt tccgtcctcg gtttttttgc
    62581 ggttgagtta aggttattca aattaatatt ttttgagtat aattacgttg tcaggctgga
    62641 ttgttttttt gacagacatg ctataataac tttaattgaa tatgaagggg agtaccagat
    62701 gaacgaacga atcaaaaaca aattagcttt acttcctgat cagcccggct gttacttgat
    62761 gaaagataaa aatggaacga tcatttatgt cggcaaagcc aaaatattaa aaaatcgtgt
    62821 ccgctcatat tttactggta gccataatac gaaaacggaa cggcttgtta gtgaaatcga
    62881 agactttgaa tacatcgtta cagaatcgaa tatcgaagca ttgctcttag agatcaatct
    62941 gataaagaaa aatgatccta aatacaacat tatgttaaag gatgataaaa cctatccttt
    63001 ccttaagata acgaatgaaa aatatccccg tttggtgatt actcgtaagg tactaaaaga
    63061 caaagcactg tattttggac catatcccga tgtcggtgcg gcgaatgaga caaagaagat
    63121 cctcgatcga ttatttcctc tgagaaaatg caaacctagt cagacgaagg agccttgtct
    63181 ttactatcat ttgggacaat gtctgtgtcc ttattatttc gacgtagatc cgaaagtcta
    63241 tacgaaaatc gttgatgaag tgaaaaactt tttaaacgga ggacacgaaa aaatcgagtc
    63301 agagatccat cagaaaatgg aaaaagctgc tgaaaacatg gagtttgaaa aagctgcaga
    63361 ataccgagac cagatccgtg ccattgagac aatcatgact cgccaaaaaa tgacaaatac
    63421 tgatttactg gatcgagatg tatttggtta tgcgattgat aaaggatgga tgtgtgtcca
    63481 agtgtttttc gtaagacaag gaaagctaat tgaacgagat gtttcaatgt ttcctttcta
    63541 taacgaagca gaagaagatt tcttgactta cctcggtcag ttttatcagg aaaatgagca
    63601 tttcattcct aaagaagtct tgattcctga tacgatcgac aagcccagtg tagaagcttt
    63661 gttagctacg aaagtgctgc aaccaaaacg aggagaaaag aaaaaattag ttgaattggc
    63721 gagtaagaat gcctcagttg ctttgaatga acggtttgat ctgattgcca gaaaacagga
    63781 acggacgatc ggagcagttg aacgtttagg aaacgcgatg aatatcccga ccccaatacg
    63841 tatcgagtct tttgataact ctaatatcat ggggacgaat cctgtggctg cgatggtcgt
    63901 attcattgat ggaaaaccgg caagaaaaga atatcggaaa tataaaataa aaacagtcaa
    63961 cggaccggat gattatgcat caatgagaga agtcatctat cgcagatatt cgcgagtgat
    64021 tcgcgaaggg ttgcctttac ctgatttgat cttgatcgat ggaggaaaag gacaagtaga
    64081 tgtggcaaaa gatgtcttag aaaatcaatt aggaatcgat attcctattg ctggcatggc
    64141 aaaaaacgat aaacataaaa caaatgagtt gctattcggt acagatttgg ctgtagtacc
    64201 gcttgagcga aattcaccag agtttttctt actccagcga atccaagatg aagtccatcg
    64261 attcgcaatc actttccatc ggcagctacg cagtaaaaac agttttgctt cccgattaga
    64321 tgaaattgaa gggttaggac caaaacgaaa aaaaatgctg cttaaagagt tcaaatcgtt
    64381 gaaaaatatc acagcagcca cgacagaaga attacaagaa atcggactgc cgaaaaatgt
    64441 cgcacaaaac gtatttgata aattacatca ggaatgagga aagggcactt tacaaagaaa
    64501 gtaaagtgtc ctatcatttt atgtacaaca aaaagagcgt ttacgttttg ttggtaaata
    64561 ataaatcgct tacgtctggt gtctaaggat atatgtgatt tcttgaagaa ggagtgaaga
    64621 aatgttagaa gtcaaggatc ttgttaaaac ttttgggaac tacacagctg tcgatcatgt
    64681 ctctttccaa atccccgatg gaaaaatcat ggggctaatt ggccaaaacg gggctgggaa
    64741 gacaacgact tttcgtttga tcttggattt tttgacacaa gaccaaggag aagtgttatg
    64801 gaatggccat catcttgggg agaaagatta tgatgtcatc ggttatcttc cggaggaacg
    64861 gggactttat ccgaaagtaa cgattcaaga ccaactgctt tattttgcag aacttagagg
    64921 gaaatcaaga aaagagattg aaccaaaaat cgacttttgg atggaaaaat ttcaggtaaa
    64981 agggaaaaag acggataaag taaaatcttt gtctaaagga aatcagcaaa aagtccagct
    65041 gatcgccacg ttaatccatg aacctaaatt gatcattttg gatgagccat tcagcgggtt
    65101 agatccggta aatgctgaat tgctaaaaga tggaatattg gaattgaaaa aacatggttc
    65161 atgtgtcatt ttttctagcc acaatatgga taatgtagaa aaaatctgcg atcatttgat
    65221 catgttgcga aacggaaaaa tggttttgaa tggaaaagta catgagattc gtgaatcatt
    65281 tggccgtacg aagttattct tggaatctgg tttaagccaa caggaagtag aagaaatcga
    65341 aggcgtgaaa aaagtgatcc ttcatgaaga caatacgtta gagattacct tagaagatcc
    65401 tgaagctggg aaagaaatct ttactcgtgc gactcagttc ggctacattc ctatgtttaa
    65461 ccagcaaccg ccaactttgg aagagatttt caaattgaaa gcaggtgaaa tcgatgcgta
    65521 agttttggat tattaccaaa gatgtctatt taaaaaatgt taagtcgatt tctttcttga
    65581 tcatgatatt agtccctttt atcatgctgg gtatcattta tgtagcagga aactttgctc
    65641 aacaaaatag tgatgtcaat aaaatcggcg tattggctga taatgagcaa atcagtcagc
    65701 aaatgagcca agtcaaaaca gatgattttg agttcaaagc agttgattct gaagaaaaag
    65761 cacaaaaaga gctttcggaa gaaaaaatcg atgcgtattt agtagtctca actgagaatg
    65821 ataagataaa tgggatgctt tatagcgaaa attcattagg acaaagtaca caactactga
    65881 tacaacaaca actgactggc ttgcaatcga tgcttcgagc gagtcaatta ggcatttcac
    65941 cagaagaagt agctagcttg agccaacaag caagtttgac tcgacaaaaa gtcaattttg
    66001 attcaaaagg aaaaatgaca gtcggagaag ataactcgac agtccaatac gtcgtaagtt
    66061 atgtagcaac gattgtcttg ttcattatta ttttgacgta tgcgcagatc attgcacaag
    66121 agatcgcttc tgaaaaaggc acgcggatca tggaagtgat cctgtccagt acgactgcac
    66181 aaaagcattt ttacggaaaa ttaacaggtg ttttacttgt tgcattaacg caaatggcat
    66241 tatacggtat tatttttggt ataggataca gtcaattcaa agatatggaa atggtcaaaa
    66301 atatattaga cggtatctca ttggataact tgattggacc attcttgtgg tattctcttc
    66361 tattcatgat ctttggcatt ttgatttttt ctgttttagc agctttatgt ggctctttgg
    66421 tcaacaaagc agaagataca gcaaaagcaa ttttgccagt gacttatcta tctctaggcg
    66481 gatacatgct tggattgata ctaggagctt cagatccaaa caatatcgtt attcggatca
    66541 cttcgtatat tccattctta tcttcatata ttatgccggt tcgcttagca aatgagacag
    66601 tcggtatggg tggagcattg atttccttgt tggtacttgt agccgtaaca ttcttattga
    66661 tgatcttgtc tgcaaacatg tacaaatcga atgtactcgt ttatagcgaa ggcggattat
    66721 ggagttcatt gaaacaatcg atttcaatta tgaggaatga acgaaaaaaa gcataaaaca
    66781 atcctaaaat acagaaggaa gctggacatc tattgttccc agcttctttt tgtatagacc
    66841 tattttattt attttactat attggatata tattcattga aaatagtgta taacaacttt
    66901 ataatattga gtataccaat ttttggaggc gttttaatgg accgttattt agatttactt
    66961 tcagaaaaat tcccctcaac ggaggatgtc atcacggaaa tcatcaatct cgaagcaatt
    67021 ttgcagcttc caaaaggaac agagttattt ttgagtgata tacatggcga atttcctgct
    67081 tttgatcata ttctgcgtat cggttcagga aatcttaaag aaaagatcaa agaccttttt
    67141 tctgaacaaa tgacggaaac ggatatcagc caattcacta tttttacggc ttatccagaa
    67201 tatgcattaa cgactgattg gtacaaagaa caagataaat cgcagctgat ccatcatttg
    67261 atcgatcttt tacggtttac gacagtcaaa tatacccggt caaaagttcg aaaaggattg
    67321 ccgaaagaat atagctatat cattgaggaa ctcttgtata tcgatgaccg tatcaatgga
    67381 aaaaaagact atgtaaaaaa aatcattgaa caacttgttt tgatgaagga agaagaaaaa
    67441 tttttaacga aacttgcaca gacgatccaa aaatctgtca tcgatcattt gcatatcgtt
    67501 ggagatattt ttgaccgagg aactcaagca gccaaagtga tggatcgaat catggatttt
    67561 tcttctgtag atatccaatg gggaaatcat gatattttgt ggattggtgc gtattgcggc
    67621 tctgaggcat gtttactgac acttttacgg attgcagcac gctataatta tttatttgaa
    67681 ttagagaaag aatatgggtt gaatttacgt ccattgtttt cttttgctca tcaaacttat
    67741 cagaagaatc cagtatttgc gcctaaaaac agtaaaaatc tatccgaaag agagcaagaa
    67801 gaattagaaa aaatccatca ggcactttct atccttcaat tcaaatcaga acatcagtta
    67861 ttggatcgtc gacctgaatt taaaatggac gatcgtaaat tgctggaaaa aatcgactat
    67921 gaagcatcaa cgattgattt agaaggtcag ctctatgagt tgaaaggaac ttgttttcaa
    67981 acgatccagc cagatgatcc aaaaaaattc ttggaagagg aacaaaaagt gattgatagt
    68041 ttgatgtatt cattccagca ctctttgaga atgcaaaaac atatgacgtt tttgatcgaa
    68101 aaagggggaa tgtatctcac gaacaatcag catgtgctgt ttcatggctg tatacctgta
    68161 gacgagaagg gacagctctt agcatttgaa ttagaccaat cttatcgcgg aaaagaactg
    68221 ctgggctttt ttgaaaaaca gataactgaa agcgcaaaag atctgactgc aaaagaagat
    68281 ttagcaaccg atttgatttg gtatgcgtgg agtgggccat tttcgccttt attcggcaag
    68341 agtaaaatgg cgacttttga acgttatttt ctcacagagc ctcatacgca cgtcgagaaa
    68401 agcaatcctt attatcactt gcgagatgaa gagtggttca gtgaaaaaat tttagcagaa
    68461 ttcgacacaa aagaagaagg gtcagcaatc attaatgggc acacgccagt aaaagtaaaa
    68521 aaaggggagt caccgatcaa agcaaatgga aaagtatttg tcattgacgg aggtttatcc
    68581 aaagcttatc aaaaaacgac aggaattgcc ggttattcac tattatgcaa ttcttatggt
    68641 ttccaaatcg tgacacatta tccgtttttg cctattgaac aacaatttgc aaaaaaatcc
    68701 gaccaaacaa atgtgaaaaa agtaatcgaa cagcaactac cacgcaaact caatcgtgat
    68761 acaacaaaag gtatggaact gcagcagcag attacccagc tcaaaaggct gttggactat
    68821 cgaaaggacg attgagaaga attccagtga acattgttcc atagactgga gactgagaca
    68881 aaagtcgtgt cgcagtctct ttttccggat aaacggtgtt cttctgccaa ctcctcggtc
    68941 acaagtcaca ctattcaaca aacatgaaaa gctgtttttt gaaattgctc cttgtgactc
    69001 agagttgaac ggcaggctca cgacctcttg gtataaacgg tgttcaaaag ccagtttctc
    69061 ggtattaagc caaatttatg caaaaatgtg aaaagccatt ttcacaaaat ttttcttaat
    69121 actcgaaact aaacagcttt ttcacaaccc cctcagaaag tctattaaaa ttcattcaca
    69181 aagaaatcga ataagcgctg ttcagatgga tgtacacggt gggtaagttc cggatgccat
    69241 tgaacaccga ggattttatg catatcatct ttgctttgaa ccgcttcaat gagtccatcg
    69301 ttagaaaaag cgatggcttt taataaaggt gaaagatctt tgactgcctg atgatggtaa
    69361 gaattcacaa aatatggatc ggggagaagg ttgcttaaca aactgtctga aacaatcttg
    69421 acttcgtgag tcgtaaattg cggggcagtg ggctgttgtt catgttttac tgaccacttt
    69481 ggatataatg aaagatcttg ataaagtgta ccttccaaaa cgacattcaa tagttggagt
    69541 ccccggcaga ctgcaaaaat tggttttctt tgtttcaatg cttccaagat cagtgcctgt
    69601 tcaaattggt ctcgttgaat atttgtttcc gttagctttg gatgaggatc ttccatgtaa
    69661 agttgtggac tgacatcttg accacctgca agaataagtt tgtcgatttg tccaatcagt
    69721 tgaggagctg aatctggaga catgactggc agaataagag gcaatccttg agcatctaaa
    69781 actgcatcca cgaatccttg cggtgtatag ctcacttgat ttccttggaa agtatctgtt
    69841 gctcgaatca gttgatttcc ggcaatgccg atgattggtt tcatttgtat tccccctaaa
    69901 gtagacttat tgtaacaagg atttaaaaaa aattaaacta tgtaagactt gcccctatac
    69961 ttatctgttc ttgctgtgtt actatctgta aagagaaatt tcgtgtgaaa ttcatgacga
    70021 tagttgaaaa tattgcttaa tttgttataa taaaaagtaa gcagaaataa aaaggttggg
    70081 cgtaagcttc aaggatctag ttcttcaagg ggtgagaagg acattttatt gaaggggcct
    70141 gcctatacta agttatcttt agaggtacat actttcaatg aaaaaagaaa gcatgtacct
    70201 cttttttaaa tcgaaaggaa gtgaagcaag tgttagaagc tttggaacaa atccgaaaag
    70261 cagaagaaga aaatgaaaag cgtgctcaaa cactgcggca gcagctgaag atctatgcaa
    70321 cagaaaaaga gcaggaattg gaaacgatcc aaacaaacta tcgacaacaa ctaaaacagt
    70381 tggtggaaga aaaagaacaa tttgaaatac aagaattaga aaaagaaaaa atgaaattga
    70441 aagcagaagc agacaaggtg caagcaactt tgaaagatca atatcaaaag catcagagtc
    70501 aagcgatcgg tgcgatcatt gaaagggtga aagaaactta tggccgtcac taagatggaa
    70561 aaagtgaccc tcatttcaga taaaagaaat caggagagga ttttacaagc agtacaagga
    70621 atccaaaacg ttgaaatccg ggatctgtat caaaatagaa caaacaacca gtgggtggag
    70681 aagtattttc cagataccac gattattgat aaagaagcaa aattaagcgc tttaggtaat
    70741 cggttgaaag acatccaaga agctatccaa ttcatacaac accacggcga tagccgtcaa
    70801 aagaaactcc atttgaaacg tcaagaactt tccttacaag atttggaagc caattattcc
    70861 gaagaaaatt tcataaataa attgaaagaa gtccttgatt taaaagaaaa gtgggaacaa
    70921 ctaactgaag aacgtgatcg tttagaagaa gaggaagaat ggcttcttca ttggcaacag
    70981 ctggatattg ctccaagtat gtatgcaagt aagacgacca tttttgagat ggggactgtg
    71041 agtgcagcaa attttgaaag tttcaaggaa gaactgagta agcttgatga cgtttatatg
    71101 gaagaaatag attatacgcc aaaacaagtt tatctttcgt atgttgcttt aaaaaaatca
    71161 gttgctgtta tagaagaaat tgctgggaaa tacgggttca ataaagaaac gtatccttat
    71221 gaacaaaatc ctaaagaaaa actgcaagag accaagcagc aattatccat tgttcacgag
    71281 cagcaaaaga agataacgac agcgttaggt cagtgcagtg gctatatcca agaatttgaa
    71341 tgggtagaag aagtcacact tgccgttgca gaacgagaaa aaataaaaga acggtttatc
    71401 catgcgactt atctgatcgt tttgcaaggt tgggtagatg cagaagaaaa acagaatttg
    71461 ctgcatgtgt taaacgaaac cgtatcagaa gaagatatat acgtcagttt cgaaacacca
    71521 aactcagaag agattcagca ggaagtccct actaaattga aaaaccatcc gcttgtcgaa
    71581 ccttttgaat tgctgactga aatgtacagt ctgccaaaat atgaagaagt agatccaaca
    71641 ccttggatga caccatttta tcttgtcttc ttcgggatga tggtcgcaga tgttggttat
    71701 ggtttgctga tgctcattgg gacaatacta gctcaaaaac tacttgttct accacgcggg
    71761 atgaaacgtt tcgtaaaatt ctttgagatt ctctcgatac catcgatcat ctggggattg
    71821 atctacagtt catttttcgg acagtcatta ccaaaagaac tgtttggcat ccgcttgcct
    71881 ttcccaatcc tatctacgac ggatgacgtc aatacgattt tgattttatc cgtgattttc
    71941 ggtctgatac agattttggt tggattattt gtggcagcaa aggaaaatat caggagaaaa
    72001 gattacttga gtgctgtcag tgatggattt gcctggcaag ggatcctaat tgggatcgtt
    72061 attgcgttgg ttggtgccat gttgataaaa aatacagcat ttgtttacct tggcgctggg
    72121 ctatcgatca ttgctgcctt atgtatcttg atcgttccga ttatccaaac gccgtctaaa
    72181 gtcaaaggtg ctgccaaagg tgcgtataat ctttacggac tgaccggcta tatcggtgat
    72241 ttagtcagtt atacacgttt gatggcattg ggtatttcag gcggaagtat tggagcggca
    72301 ttcaatatgc tagttgcttt catgccgcca gctgctcgat tcagtgtagg gatccttttg
    72361 atcatcgctt tacacgcact gaatatgttt ttgacactgc taagtgccta tgtccatggc
    72421 gcacgattgc agtatgtcga attttttggg aagttttata caggaggcgg acgtgccttt
    72481 gatccgctga aaacggcgga aaaatacgtc aacatcaatc acaagaaaaa aaacaataaa
    72541 taattggagg atttttatat aatgatggat tacttaatta gtcaaaatgg tggaatggta
    72601 tttgcggtat tagcgatggc aacagcgacg attttttcag ggatcggttc agctaaaggt
    72661 gttggaatga caggtgaggc agcagcagca ttgacaacaa gtcaacccga aaaattcggg
    72721 caggctctga ttctgcaatt gcttccaggt acgcaaggtt tgtatggatt cgttattgcc
    72781 tttttgattt ttatcaactt aggaaatgac atgtcagttg tacaaggact gaactttcta
    72841 ggtgcttctc tgccgattgc ttttacaggc ttgttttcag gtattgccca aggaaaagtc
    72901 gcagcggcag gtattcaaat tttagcgaaa aaacctgaac atgctacaaa aggaatcatt
    72961 tttgctgcga tggttgaaac atacgcgatt ttaggtttcg ttatttcctt cctattagtg
    73021 ttgaatgcct aagcataaag gaggaaaagc agatgaacgc cattgaaaaa atcatctctc
    73081 agatgaacga agcagcagag caggaaagag cggcgttaga acaagaagag cgaatgaaga
    73141 tcgatcaaaa ctttgaacaa aaacgtacgc aagttgaaac agaacatcaa aaacaaaaag
    73201 aaaaacaaat cgaattactc gaaaaaaaat accgtcagct aaggaatcgc cagcaagtag
    73261 aagtacgaca agaaaatttg aatgcgaagc aggaattttt aagacgattg tttgcagatg
    73321 cggtaactga aatggaaaat tgggatgaat ctgaacaaat ccagtttatc aaaaatgcat
    73381 tgtattcatt acctttgaca ggaaaagtag cattcattgc tggagaaaaa tcagcagcct
    73441 atctttctca gacgttgttg gatgaatgga acaatgaact tccctttatg atggttttaa
    73501 gtgatgaaac tgttgctgat caagcgggtt ttctgataaa cgatcaagga gttcagtata
    73561 attttctttt cagcagcctt gtacaagata tccaaggaac gatgagtttt gagattgcca
    73621 atcaattatt cgaataagga gggatcagtg tatggaatac cacgaactaa atcccttgat
    73681 tcgcggaaga gagcttgaac ttttgtccaa tgagacattt gaacggatga ttcaaacaaa
    73741 ttctgtcgaa gcacttggtg aaatattgaa atccacgatt tacagtccat atatttatga
    73801 cggatatgaa tatgacttcg aacagaatct tttaaaggag cagagccgtc tatttcgctg
    73861 gttaaaggaa tcagcaccgg agcctgaaat cgtttggatc tatacgatgc gttatacttt
    73921 ccataatctg aaggttttga caaaagctga gatgacaaat caaaatctgg accatttgta
    73981 tatcgacgat ggattttatt cattagaaac cttgaaggat gccattcata cgcaagtttc
    74041 aaatgaactt cctgaaagca ttatggacag tatacgagaa gtacgtgatt attttgaaga
    74101 gtctaccatt cttcagggaa ttgacgtgat ttatgatcga cagtttttga cagagcagcg
    74161 acggcttgcc gataagctag gatatcaaga attgctgaca gaagtcattg cttttattga
    74221 cttgaccaat atcacaacga tggctcgagg aatattgcag aaaagaacat atgggttcat
    74281 gacgacggta ctttccagct cgggaagtat cgaaaaagaa gtatttttga actttgtaga
    74341 taaagatatg gaagattaca cgaattttct attagagaca gattatgctg attttctgcg
    74401 ccctgtcatc cgtgagggaa atattgatct cgtaaagctt gaacagttga aagatgatta
    74461 tctaagttca ttgtatcaag aagcacaaac ccaggctttc ggaccactgc cactactagc
    74521 ctttttgaac gcaaaagagg tagaaagcaa aaaccttcgt ttactggtta tcggcaaaag
    74581 aagccatttc gaatcagaaa caatcagaaa gcgggtgaga caagtctatg acgcataaga
    74641 tcggtgtagt tggcgacaaa gattctgttt tgccattcaa attgtttggc tttgatgttc
    74701 gttatggtac aaccaagcaa accgttcgtc aggcaattga agaaatggca aagaatgagt
    74761 atggcgtgat ttatgtcaca gagcaatgtg cagcattgag cccagaaacg atcgaacgtt
    74821 acaaggaaca aatgatacct gctatcgtat tgattcccaa tcatcaagga tcattaggga
    74881 tagggctgga agaaattcaa aaaaacgtag aaaaagcagt aggtcaaaat atcttatagt
    74941 atgaaaagga gatagaaatt ttgcaaattg gaaaaatcat aaaagtctcc ggacctcttg
    75001 taatggctga gaacatgtct gatgccagta tccaagacat gtgtctagtg ggagatctag
    75061 gagttatcgg agaaattatc gagatgcgtg gcgatgtggc gtctattcaa gtatatgaag
    75121 agacttctgg aattggtcca ggcgaaccgg ttcgctctac tggtgaagct ttatctgttg
    75181 aattaggacc agggatcatt tcacaaatgt ttgacggaat ccaacggcca ttagatacct
    75241 ttatggaaat cacacaaagt aatttcttag ggcgcggagt tcaattgccc gcattggacc
    75301 atgagaaaaa atggtggttc gaaccaacag tagaagccgg agaaacggtg agtgctggag
    75361 atgttatcgg gatcgtagaa gaaacaaaag ttataaaaca taaaatcatg gtgccaaatg
    75421 ggataaaagg aacgatcaaa acaatcgaaa aaggttcatt cactattgat gaaacagtat
    75481 gtgtcattga aaccgaaaat ggtgacaaaa atttgacgat gcttcaaaaa tggccagtaa
    75541 gacgtagtcg gccaatcaaa gaaaaattaa acccggatgc acccatgatc actggacagc
    75601 gagtgattga tacattcttc ccagtgacaa aaggaggagc agcagctgta cctggtcctt
    75661 ttggtgcagg gaaaacagtc gttcagcatc aaattgcaaa atgggccgat gtggacatgg
    75721 ttgtctatgt gggatgtggc gagcgtggaa atgagatgac ggatgtttta aatgaattcc
    75781 ctgaattgat tgaccctaat acaggagaat cgttgatgga acgtacggta ttgattgcta
    75841 atacatcaaa catgccagta gcagctcgag aagcttctat ctatacggga atcacaattg
    75901 cggaatattt ccgtgacatg ggttatgacg ttgctatcat ggcagactcc acttcacgat
    75961 gggcagaagc acttcgtgag atgagcggac gtttggaaga aatgcctggt gatgaaggtt
    76021 atccagctta tcttggttca cggcttgcgg aatactatga acgatctgga agagtcattg
    76081 cattaggatc agaaggtcgc gaaggaagta taaccgcaat cagtgctgta tccccgtctg
    76141 gaggggatat ttcggaacca gtcacacaaa atacattgcg ggtcgtaaaa gtattctggg
    76201 gtcttgattc cagtttagcc caaaaaagac attttccttc gatcgattgg atacaaagct
    76261 attctcttta ttcaacagaa gtagggaagt atatggatca tatccttcaa gctgactggg
    76321 catccatggt caccgagggc atgcgtattt tgcaggaaga acagcagctg aatgaaatcg
    76381 tgcgtttggt agggattgat tccctttcag ataatgaccg tctgacatta gaagtggcaa
    76441 aatccattcg tgaagattat ttgcagcaaa atgcttttga tgatgtcgat acattcactt
    76501 caagagagaa acaattcaaa atgttgaaga tgatcttgac ctttggtgaa gaaggacgcc
    76561 gtgcgttgtc gttaggtgct tatttaagtg agatcatgga cggtaccgta tcgattcgtg
    76621 aaaggatcgg acgaagcaaa tatatcccgg aaacagaatt agaaaaacta gatcaaatta
    76681 ttggtgaaat caagcaaacg atgcaaacga tcgtttcaga aggaggcatg agcaatgatt
    76741 aaagaatatc gtacgatcgg tgaagtcgtc ggtccattga tggcggttga aaaagttgct
    76801 ggtgtcaaat atgaagaatt aatcgaagtc cgtatgcaaa atggcgagat tcgtcgtgga
    76861 caagtattgg aagtccaaga agataaagca atggtccaaa tattcgaagg aacaagtggt
    76921 atcaatttac gtgactcttc tgtacgattt ttaggccatc ctttagaact aggtgtatcg
    76981 gaagacatga tcggtcgagt attcgatggt ttgggacgac cgaaagataa cggaccagag
    77041 atcctgcctg aaaagcattt ggatattaac ggagaagtaa tcaatccagt agctcgggat
    77101 tatccagatg agtttatcca aacaggtatc tctgcaatcg atcatttgaa tacattagtt
    77161 cgtgggcaaa aattaccagt attttctggc tctggtcttc ctcataaaga attagctgct
    77221 cagatcgcgc gacaagcaac ggtactcgat tcatcagatg atttcgccgt agtctttgct
    77281 gctattggaa tcacttttga agaagctgaa tttttcatgg aagattttcg tcaaacgggc
    77341 gcaatcgacc gttctgtcat gtttatgaat ttagcaaacg accctgcaat cgaacgtatc
    77401 gctactcctc gtatggcttt gactgctgca gaatatcttg cttatgaaaa gggaatgcat
    77461 gttttggtta tcatgacaga catgaccaac tatgcagagg cattgcgaga gatttctgca
    77521 gcacggcgag aagttccagg aagaagagga tatcctgggt atctttacac gaacttagct
    77581 actttattcg aacgagcagg aagaatccgc ggactaaaag gatcggttac tcaaattccg
    77641 attctaacaa tgccagaaga cgataaaact catccaatcc ctgacttgac tggttatatt
    77701 acagaaggac agatcatctt gactagagag ctttacaaga gtgggattca gccaccaatt
    77761 gatgtactcc cgtctctttc gcggttaaaa gataagggaa ctggacccgg aaagacaaga
    77821 gaagaccatg cagctacgat gaatcagctt tttgcagcct atgcacaagg aaaacaggca
    77881 aaagaattag ccgtagtttt aggtgaatct gctttatctg atgtagacaa gatctatgcg
    77941 aagtttgctg agcggtttga aaaagaatat gtcaatcaag gattctacac gaaccgttcg
    78001 attactgaaa cacttgatct agggtgggaa ctgctatcga tgttgccaag aaccgaatta
    78061 aaacgaatca aagacgacat gctggacaaa tatctgccag aagggaagtg agttctgatg
    78121 gcacgattga atgtgaatcc gacccgcatg gaattgactc gattgaaaaa acagttgaca
    78181 actgccacaa gagggcataa attattaaaa gataagcaag atgaactgat gcgtcaattc
    78241 atcctgttga ttcgaaagaa caaccagctg cgtcaagaaa tggaagagtc tatgacagaa
    78301 gcaatgtctg attttgtatt ggcaaatgct tcgatcacgg aacctttcat cgaagaatta
    78361 tttgttttgc cggcggaaaa cgttgatttg tctatcgtag acaaaaatat catgagtgta
    78421 aaagtacctg tgatgaattt tgaatatgat gaacagctga cagacacacc tttggaatac
    78481 gggtatttga attccagtgc cgaactggat cggtcaatcg atcggtttac taccctgctt
    78541 ccaaaacttt tggaactgac agaaatcgaa aaaacttgtc aactgatggc gagtgaaatc
    78601 gaaaagacac gtcggcgagt caatgcatta gaatatatga cgatccctca attagaagaa
    78661 acgatctatt atattcgtat gaagctggaa gaaaacgagc gcgcagaagt aacaaggttg
    78721 atcaaagtaa aaaatatggg taccactgac taagtggtat ctttttttaa aagaggaaaa
    78781 cgatgattaa acaaagcaaa caaataaaga aacgtttgcc ggctgttcag cttctcgcat
    78841 taggattttt tctcctgatt ttagttggcg gcggcctact taccctacca ttttttagta
    78901 atagtgggca tgggacaaat tttatcgatg cgcttttcac tgcaacttct gctgtctgtg
    78961 taacgggatt gacaacattg aatacagcag agcattggaa cagtgctggt caatttttga
    79021 tcatgctttt gattgagatc ggcggtcttg gttttatgat ggttccgatt ctatgctttg
    79081 cattgataaa gaagaaagtc agtctcagca cacgtattat attaaaagaa gcgctgaatc
    79141 tagaagaagt atcaggtgtg atgaagctca tgctttacat cctaaaattg gcctttgtga
    79201 tccaattgat tggtacggtt gctttatctt ttgtatttgt gcctgaattt ggctggttga
    79261 aaggtatctg gtacagtttg ttccatgcaa tctctagttt ttgtaatgca gggtttgatt
    79321 tgttaggaga cagtttagcc aatcaccagc aaaatgttta tttgatcatg gtggtatctg
    79381 ctttgatcat ttctggtggg ttaggcttca tcgtatggcg tgatttactg gaatatcatc
    79441 agaaaaagaa gatgacgatt cattcaaaaa tcgcattaac cgttacaggt acccttttat
    79501 taggcggatt cgttgtgttc tttttcacag agcgcaatgg ggcaacgcta gtggaaggga
    79561 atatgtttca acgattggca aacacctttt ttatgagtgt gacacctaga acggctggat
    79621 attattcagt tgattacctc catatgagcc atgcaggtct gattttaacg atgtttttga
    79681 tgtacatcgg cggaacatct gggtcgacgg ccggcggatt gaaaacaact acgttaggtg
    79741 tgttgctgat ccagatgcgt tcgatgttga aaggacgtac gagagcggaa gcatttggcc
    79801 gtaccatccg acaaggcgca gtgttgcggg cacttacttt attttttgtt acgttgacgt
    79861 tgtgtgtagt cgccatcatg attttatcgg tgactgaaac gatacctaaa acttctggca
    79921 tcgaatatat tgcttttgag gtcttctctg cgtttggtac agtaggtctt acgatgggat
    79981 tgacgccaga cttgactgca atagggaaat tgatcattat agcgcttatg tacattggac
    80041 gagttggtgt attgactgtg gtcttctctc tgatgacaaa agcacaaaga acacaatcaa
    80101 aatacaaata tccagaagaa agtgtcatga ttggataatt tcatcttctg acagaaacct
    80161 agtgatttag taaaataaga aaataaaata atttttcttg cttcttggat actttaagtg
    80221 caaaatgttc gtttattttt tgaggcacta cccgttgttg aacctcgggt agtgcctctt
    80281 ttttattgaa aggaatcaat aagatttgat tcctttattt atcaataggt tataattcat
    80341 atttttttat tttttctttt acgatactta gtccagaagc taaaatttca aggttattag
    80401 aggataggga aattcgaacg aatgcatctg gttgcgtacg tgtagtaaag cgtctggaat
    80461 gataaagtcg gataccgtta gcaagaaagt cattctcaat tatcttaggg tcaatctcag
    80521 gatcaactgg aagaattcga tagtaaggga cacgattcgt tggtttttct actttgaaaa
    80581 gagaatcaaa aagctgattg gctctttttg taagacttaa tttagtttct aagatcctat
    80641 ttgcttcatt tgaatggagg atttgagtga tgacttccac atctaatcca gaagttttca
    80701 catttatatt aaaaattgct tgttctatct tgctttggac atgtactgga actacaagat
    80761 aagcaactcg caatccagaa caaataaatt ttgtcattcc agctaagtag attgtttggt
    80821 taggtaataa attttggaaa ggaggaatga tcgtatgttg atagtaagtt gttaaaaatg
    80881 aatggatatc atcttcaata acccatagac cttctttttc aatcacttcg gctaattgct
    80941 ctcgtctttt gtgagagatt tgaaacccta taggattatt acaagaaggc ataagaaaga
    81001 caccatgaat cttctttttt ctacattcct gaatcaatat atcaggtcgc attccttgct
    81061 cgtcaaaatc aattggaacg atctctaaat gatataactg agccaattca atgaaattag
    81121 cgtatgtata tcggtctgtt gctattctat cacctggaga gaaaagtgca gaaagtgtga
    81181 tagccaatcc attttgaaca ccggaaacaa tagatagaga ttctaaggac ggaatgactc
    81241 cttgagtttt taaccaattt gctgcagtag tcaattgaaa atttgtgcct ttgggatctt
    81301 ggtaattaag caaaccaaca agatttgggt tattactagt tgattgaata aacgggacaa
    81361 cgaatttatt acattcttca aaagaactaa ccagaccaaa atcaatgata tgttcggtta
    81421 cttcattggt agagatggtg atggactcaa agacattggg agaaataaat gtgccacttc
    81481 caatattcgt atacagcaaa cctttctcaa ttccatattt ataagccttg ccaacggtag
    81541 taaaatttaa atctaaataa tcagctagct ctctttggga gggtaactga gtgtttttct
    81601 gtaatttatt ctttaaaata tcttgttcta attgttgaat caacgatcga taataaggac
    81661 gcttcaattt ttgtttgtct ggtcgccaag ttaacgggta attgtcataa gaattaatag
    81721 gcattttctc cactccttaa aattgtatac catacaattt taccattgat tgtattgatt
    81781 ttagaagtta atcttttgtg aggagggaat tgtctatgaa aattattaat tttgaggaag
    81841 tagtagcttc ttttagtttt gaagaagcga ttcaagtaat gaaaaaatgt ttttttgatt
    81901 atgaaagtgg taaaatcagc caaaatcctc gattggtgga aattttacct gacggaaaag
    81961 gcaaaaatat gtttgcgatg atgcctgctt atttggggga gaacagatat tttggcacaa
    82021 aagtcattac cgcttttccg gataatcatc agtatcattt accttctcat ttaggagaga
    82081 ttttcttgtt tgatgctcaa aacggactac ccaaagcatt gataaacgca aatgcagtca
    82141 cctggattcg aacagctgct gtatctgcgc tggcaacaga ttacttagca aatccgcatg
    82201 cagaaacact tgctttaatt ggagctggtc aacaagcatt gtcgcatttg actgcgattt
    82261 ctaccattcg tcccatcact acagtgtttg tttacgatat tttagaagaa agacgaaata
    82321 cttttatcgc taaagctaaa aaacagtatc ctaaaataac gtttataaat gcaatatcag
    82381 tagaagatgc agtacgtcca gcggaaatca tttgtacgtt gacctctagt aaagaggcat
    82441 ttcttcaaaa agagtgggta agggaagacg cacatatcaa tgctgtgggc acatttactc
    82501 ctgatacaag agagataagt acatcgttga tggaaacttc tcaaatctat gtagatgatt
    82561 actcagctgc cttaacagaa agcggggacc tgcttatagc catggcagaa ggagatttag
    82621 aggaatcttg tattgttggt acattaggcg aattagtttc tgagaaaaaa acattttata
    82681 aaggagaatc gaggccgacg attttcgacg cagttggtct agctattgaa gatctttgtt
    82741 gtgcagaata tatttataac aaattagaga aaggggcttt aaaatgaact tagattatta
    82801 cgtagttgat gcatttgcag atgaggtgtt caaaggaaat ccagcagcgg tttatgtgct
    82861 agaagaatgg ctgccagaag gtacgatgca aaaaattgcc attgaaaaca atttatctga
    82921 aacagcattt acagtgaaga aaaaccaaga atttgagctt agatggttta cgccagatcg
    82981 agaaatcgat ctttgtggtc acgcgacatt agcaacagca tttgttttat ttaactatta
    83041 caaaatacct gatgaaacga ttaaattttc tactcaaagc ggtaatctat ttgtgacaag
    83101 aattaaagat tattattaca tggattttcc tagtattatg ccgaaaaaag tgccgatatt
    83161 gtctgaatat gaagaagcga ttggggctaa gattaaagaa gcctacttag cacgtgattt
    83221 atttttcgta ttagaagatg aaaaaacggt ggctaaattg cagccagatt ttacagctat
    83281 caaaaatttt gaattaggaa taggagtcat cgtgacagca gaaagtgtgc aaaaagactt
    83341 tgtttctaga accttctttc caaaattaac aatcaatgaa gatccagtat gtggatcagc
    83401 acattctaat cttattcctt attgggcaga aagaatgaat aaaacaaaat tgtcagctta
    83461 tcaaatgtca tcaaggggcg gggatctaga atgtgaatta aaagaagatc gtgtgataat
    83521 aggaggaaaa gcagttttgt tttctaaagg tacctcgttt atttgatttc tttcaaatga
    83581 attaaaaata aattggtgga gagtggcaac cttatagcta caatggttgt taaaaaaaga
    83641 cgcaaacttt ttcaatttaa tgaaaagttt gcgtctcatt ttaattattg gtgtttgttt
    83701 tttattcaat caagagtaaa atgccccata ctaactatcc tcggatgact tcgattttat
    83761 aaccatcagg gtcaatgaca aagtagtaag aaggcgcagt gccaggtaat ccttttaagt
    83821 cagtaatctc aagaccagca gctttatgtt gctcgtgtaa tttttctaga tcatcagctg
    83881 ctatagcgat atgaccatag ccgtctccta gatcatacgc accatgatca tagttgtaag
    83941 tcaactctaa ttcatagtca tccccaggaa gtgtcaaata aacaagtgta aatttgtttt
    84001 ctggaaaatc acggcggcgg ctttcttcaa aaccaaatgc cttttgataa aattcgattg
    84061 atgcttcaag atctttcact cgaacacatg tgtgagccat tttcatagat tcatctctcc
    84121 ttttcctttt actcaatcat aacaaaaaga agtaaggaaa tagttgattt gtgcttgttc
    84181 atgagaaatt tctcatgtaa aatggataga aaataaaact gttaaggtgg aaactattca
    84241 tggataaacc aatttttggt gaaaaaaagc aatttgctga ttatcaaacc cgttatgcag
    84301 catatattgt catagaaaga gatcagcaga ttgcagtaat cgaggctcca aatggtgctt
    84361 tttttcttcc tggcggggaa attgaaggag aagagacgaa agaagaagcg attgtccgtg
    84421 agctgataga agaaatggga attgtggcag aaatttcttc ttatctggga gaagctgatg
    84481 agtattttta ctcgaattat cgtgcaactt attattataa tccaggatat ttctttgttg
    84541 ctgattcttg gaagcgtata ggagaaccaa ctgaaaagac caataaaatt tggtgggtga
    84601 gccctcaaga agcgcttgtg aaattgaaac gtggtagcca ccgatgggca gtcgagagat
    84661 ggatcgaaaa aaataaaaac tgaaagaaag cgagtagatc agctttctct cagttttttt
    84721 atttattaca gtacatattt tttgattgct tcagctacac cgtgctcgtt gtttgatgaa
    84781 gtgatgacat ttgctgcttc tttgacaaga gaaacggcat ttcccattgc tactcctaga
    84841 ccagcatatt caatcatgga taagtcgttc tcgttatctc cgatagccat gatttcatct
    84901 tgatcaatac caaggtgctg tgcgagattc gcaactgccg cacctttact tgcttcttta
    84961 tttagtactt cgaagtaata gggcgcactt ttgaccgttg tgtatttatc acggaaagtt
    85021 tgcggtaaac gcgcaattgc tgcatctaaa atttctggtt cgtcgatcat catcattttg
    85081 acgatgttca tgtctggtgt catttcttca ggtgttcgat attttagcgg catcttgact
    85141 aaacttgctt cgtggatcgt ataagcgctg atatctcgat taggcgtgta gatcgctttg
    85201 tcatcgatcg aatggagatg actgccgaca cggcgtgcca tcacttcgat ctctaggaaa
    85261 tcttcatgtg tcagtccgtg acgggcgatg attttacctg atttcgtttg ttgtacgagt
    85321 gccccgttat aagtaataac gtaatcatta tcttgaaaaa ggttcaactc gtttaactgt
    85381 tcctggacac ctggtaaggg acggccagtg cataaaacga tcgaaacacc ttttgcaaca
    85441 gcagcggcaa tcgcttcttt tacttctttt gttacttctc ttttctcatt taataaagta
    85501 ccatcgatgt cgatagcgac tagtttgata gacataattt cctccaatat attttaattt
    85561 atttcaatca atgcgccatt acggatatgg ctggcaaatt cttgataagt ttcgtcaaat
    85621 aaatcataat gatcacgcaa ggacggatca accatttctt ttggaaagaa aaatcgctca
    85681 tctccttgtt cttgtcccgc taatgcagca acaagctgac taacctgtga taattctatc
    85741 aaagttccgt catttcgcaa aatctcgatt tgtgtgcgat gtctgccttg ttctgggcga
    85801 taaaaatcat aaggtagatc gtagctagaa ttcacagcag tgtaataaac aggattatat
    85861 ccgacctttt ctactaacaa agtgagttct tggactaatt ttgaatcccg gttgccagaa
    85921 aaagtagcag atttcagtgg tttacgattc aaaaaacgtt tagctaaatc atttaaaata
    85981 ggatcagcag attcagacca ttgagtaaag taagtgccca agaccccatc atcaagtttg
    86041 aggtattctt ctaaagtaaa gcttccgtca agaaatggca gaagtaattg agaatggagt
    86101 tcaaaactgc tggcatcttc ttgatacaac tcgtgtgcgc gatgaagcag atgctccaaa
    86161 attacttcca taccacggga aacaggatgg aagtacactt gcacatacat ttgatatcgg
    86221 ctaacgatat aatcttccac tgcatgcatg ccactcatgg aaaaagcgat cccgccttca
    86281 taaggacgaa tcacacgtaa tattcgggta agatcaaatg ttccatattc tgttccagtg
    86341 aaataagcat cccgaagcaa atagtccatt cgatctgcat cgatctgact agaaatcatt
    86401 tggacaactt gtgggttggg gtaagttttt tggatcacac tagctacctt ttcaggaaaa
    86461 ccttcttcta ctcggttaag aatctgatac acttctgttt ctggagaagt gatgatctct
    86521 acagtgatgg cttcatgatt cgtatggaag atatgttcaa atgtatgaga gtaaggacca
    86581 tgaccgacat catgcaacag tgccgcacat aaagtcacca gccgttcctg atcatcccag
    86641 cctccgttgc ctattttttc ttttgaaaaa tttcgagaaa agatatcgca gattcgtctt
    86701 gaaatctcat aaacgcctaa tgaatgagta aaacggctat gttctgctcc gtgaaaagtg
    86761 aaagaagaag tgcctaattg tttaatgcgt cgtagacgtt ggacttcttt cgaattgatc
    86821 aaatctaaga ttacttgatg ctggacatgg atatagttat ggactggatc acgaaaaact
    86881 ttttccatag gcagcatttg atatttataa ggggttgtca taatgtagct cctttatgtt
    86941 attacgttgt tccattctct ggatttggtt gttccattgc tccagctgga tttctttttt
    87001 tagccagtcg gtagaatcct gtaaatcact tgcagaatac agcttttcaa aagcttttgc
    87061 aaatgcttct ttgacttctt ttacaaaaag gggttggtca agcagttctt caagtgttgc
    87121 cattgtagca ggatccactg caggatagcc atttgtacca aagtcttctt ttaaagcaga
    87181 ttgataaaat cgcttcatga cttgcccgcg tttttcctga ttaccgttga cacttaagta
    87241 catcataaca gaaatcccat ttttgatccg acgctgagcg ataccggcaa attttttgcc
    87301 atggatgctt aaatcataag ttccaggaca ataagaatgg gtgatttcga atgcttgtat
    87361 cggtgccttt ggaaaagcgt atttagtcaa taggagcatt tgctcgtaag cgtcatctat
    87421 ggttattttt tttgtgtcac tttgggggaa aatcaaagaa atattcaaaa ttccttcatc
    87481 tgatacgatc cctaatccac ctgaatttct gatcactgga gcgtaacctg catctttcag
    87541 tgtttggatc ccgtcactta gaaaaggagt tcgaacatcc ttcataccta agatgactgt
    87601 gcagtcatat tgccagaaat gtaaaaagat ttgctggtgt tctttagaat attccgttaa
    87661 tatatctgtt aatgcaaaag gggaaaagtc gtttttttga taaatgtgct gatctagtcg
    87721 aatcgcaggg ttcattcaac cggctccttt gtataaattc atattttcta caatattata
    87781 ctctaaaatc aaagagttgt tttggaaaaa aggttttctg taaaaatgga caagttggtt
    87841 gacaaaacaa aagaaactag gaacaatgta gctatgagaa gtaaaggaga atgaataatg
    87901 gaattatcac aaggaacacc gatttcaatc aaattgcgta caaaagtaaa acagcaaggg
    87961 gaagtgcaag atttttattt tgatttgaaa gggcaaatgg tgacaattgg cgatacgctg
    88021 tacatacgtt ataaagagat tcaggaggag acgggcgatg agattcctgt aacgatcaaa
    88081 ttagttccag atggtcatgt acagctgatc cgtgcaggag aaatgcggat gcgtttgaaa
    88141 tttggctata aagaacggtt agaaacatcc tatcgaacac catacggtat gatccagatt
    88201 gctactttta cgaaagaact gcatgttagt ttgaaagacc gtcccacagc agggaaggtt
    88261 cgaatcgatt atgatctgtt catgggaccg gaaaaaatcg gcgaatatta tttgaccttg
    88321 gattttacag cgtaaatata aaagaaaagt ttgatttttt gtgtctgatt ttgtatgata
    88381 aggagtagac tgtgaaagga cgtgtcctga ttggaaatta gtgtatttga aggtgcaaac
    88441 aaaagcgaat tatcaatgat cgaagtagca cacgcgatct tagaacaacg tggcgatgtc
    88501 atggattttt ctgatttagc taaccagatc caaaactatc ttgggaaatc agacagtgaa
    88561 attcgtgatt cactcgcaca attttatact gacttgaata ttgacggcag ctttatctca
    88621 ttaggggata atcgttgggg cttgcgttca tggtatgcta tcgattcgat cgatgaagaa
    88681 gtaaaccatg gaatggacga agaggatgaa gatactccac gtcgccgtaa acgcaagaaa
    88741 gtcaacgcct ttatcaatga tgatgaagac gcgatcgatt acaatgacga tgacccagaa
    88801 gatacagatc tgacagaaga agatgacgat gatctgtttg atgacgatga tgatgaagat
    88861 gaagaaatcg ctgcttataa ttctgacttg caagaaatcg gagcagatga cccgacagat
    88921 gatgaagaag acttgccagg aaatatcgaa gaagatttaa gtatcataga cgaagacgat
    88981 gatgatgaag attatgaaga ggaagaattt tctgactctg aaaaagaata aacattattt
    89041 tcttacgaga ggttgtgaca gagacgatca gcctatcaga ataaggaggt gtgacacgat
    89101 ttttgtcaca ccttcttttt tgtatataaa aatcccaagt aaatacataa aaaataaaaa
    89161 aattgaaact tttagcgcac cttgtacgtc atattaagtg aggcagaaag gagtggagaa
    89221 tgatttttac tggatataag aaaaaacggc agatcgaaaa ataccgtcac ctgctgaatg
    89281 gactcatcga aactgattat caaaaaatgt tccgtatcac gatgaattac gtacatgata
    89341 aagaagaggc cttagatgtg atgcaagata gttttcataa agccctgaac tattttgaaa
    89401 aagaaaaaga gatcgagcat tttagtgcat ggttttatcg gatattgatc cgcacggcat
    89461 tagatagttg gcgcagacaa aaaaggacgc ctgtggactt atttgaaatt caagatatcc
    89521 cccaacagtt acctttagaa acttccgttg cagagctcca tatgatttta gataaaatag
    89581 acagtccgga aaaagagatt ctgatcctct acttttttga aggatttcgt ttgaaagaaa
    89641 ttgcgactat cttggatatg aatgaaaaca cagttaaaac gaaaatgtac cgctcattga
    89701 atgctttacg tcaaatccta gaatgaagga gagaagagtg ccatgtattc ccaaaaagaa
    89761 aatttaaaaa aactaaagaa aacttataaa gaacaagcaa ttcccaaagg gcttaaagag
    89821 gagatccgcc agcgttttat tatcgaagag caatcattta taaaagcaaa gcggagaaag
    89881 agacgtctcc aagggttcgg agtatctttg gctatcgtaa tgattacaac aagtagcctt
    89941 ctttttaata gtcaagttcg aagctttgca gaagatttac ccatcttagg atcagtcatt
    90001 gaattgatct taggcgaacg ctttactgat cgatctgaaa aaatcgatat tcaggtaccg
    90061 aagatcaata cacaaaatga gaaagaaaat aaaacaattc atggattaaa tcaaaaatac
    90121 tttcgcgaag gacaagcaga ttttgaaaaa gctgaaaaag aatatggaaa ttttgaaacg
    90181 gatcattacc aagttttggg agattatcag aaaatcgtag acgataaccg gtttctcgtg
    90241 attgaaaggc agatcaccca aacagcagca gatagccatg ttgaaaaaag atacgacaca
    90301 atcgacaaga aaaacagtgt ccagctctca cttccacttt tattcaaaga tgacacctat
    90361 ctatctgttt tgacaaaaga agtcaaacgg cagatggccg aacaagtcaa ggaagatcca
    90421 tctaagtact attggactga gcaagatatt caagaaggga cgatagaaaa accaacactt
    90481 gttacgccta cacgaagttt ttatttgaac aaagagcatc aattagtttt gactttttct
    90541 caatacgaaa ttgctcctgg ttatatgggt acaccagaat ttgtcattcc taagtccgtg
    90601 acaaaaacga ttttggcatc ggaagattat ttggatcatt agacgagaag tagttgcgac
    90661 tagcagtttc aattttcaag taagtacaag taaataataa gaagagaaaa agagaaagaa
    90721 gagatatagt gaaaagaaat tatttagtta tcagtattat tgctttatcc gtgcttttgt
    90781 ttttcgaaat tacttcggtg gcctccttga tcaccgaagt aaaaggacaa acacactctt
    90841 cggagcattc gtcacaatct ttcaaacaat cagaacaatc aaccattaaa agccaatcaa
    90901 ctgaaacagc taacgtcaaa gaagccattc aagaatcagc ggaaaaggta caaagtcagt
    90961 catcacaatc aacacaagac agtacaaaaa cgagccgaga tccggctgtc aaaagcgtcg
    91021 caatcagctt tgatgatgga ccaggagcga ccacaacacc gcagcttctg cgaatcttaa
    91081 aagaaaaaaa cgtgcatgcc acttttttcg tcttaggaga aaatacggcg cagcatcctg
    91141 aaatcgtgaa gcagacagct gaagcagggc acgagattgg caatcacaca tacgatcatc
    91201 agaatctggc cactctttct gcccagtcga tgacggagga agtgacgaaa gcagacactg
    91261 agatcaaaaa agtcactggc aaaaccccca cttttgttcg tccgccctat ggttctgtca
    91321 cgaatgtagg agcaacgatc atccagcgac cgatcatcga atggtctgtt gattcagaag
    91381 attggaagac aagaaatcct gatttgattt tgcagaagat ccaagcaaca gtatacgatg
    91441 gggcaattat tttattccat gatatctatc ctgaaacgat tcgtgccgtt cctcaagtga
    91501 tcgattatct gaaagagcaa gggtatcgca tcacgacagt tggggattta ttagggcatc
    91561 caacggctgt cgagaactat tatggcagaa acgatcatcg gccagttcag taagtgagac
    91621 aagtatcttt aataaataac acattttaat aagtagttga acacataact accttacttg
    91681 caaaggctta acaatatcta tacaggtaca acaaaaaact gtccaccaat tttctttggc
    91741 ggacagtttt cacttaaaaa taaagaagca actattcgta aattatgcta aaatagcagt
    91801 agaacgcgtc ctgagggaat cgaacccccg tctcaagaac cggaatctta cgtgatatcc
    91861 actacactaa ggacgcaagc actgggataa ttgtaactaa acagataaaa aattacaagg
    91921 ggattggaca aaaaaatgaa atttgagcaa aatttttcac aaaaacagca gcagacacag
    91981 aaactagcca tgacgcaaca gttgcaacag tccatccaag ttttacaata taacagtgag
    92041 gagctgttgg cattcgttga gaatcaagca atggaaaatc cattggtgga agttgttgag
    92101 ccggaatggc agccagatta cataaaagct tcttcatctt cttatgaagg agaagagaca
    92161 aattacctaa atcagattcc tgatacaaaa gggtctttat ttgattcatt gatcgaacaa
    92221 gtccatttga attaccgaga tacttttttg aggaaaatcg ttctttatct tgtagaatac
    92281 atcgatttga acggattttt gacgattagt ttagaagaag ccggaaaaga gattggagct
    92341 acgcctatcc aaatgctcga tgcgttgact ctgattcagc aattagaacc agctggagta
    92401 ggtgcacgta gtttgcaaga atgtctcatg cttcaaacag aacgagatga ttatgcgccg
    92461 gaattagctt atatcgtgtt ggaagaatgt tttgaggaac tggtggagcg aaaatggaaa
    92521 gaaatcgcac aacgtttttc tgttgatcta catgctgttc agcagatatt cgactattta
    92581 caaacgttga gtccaagccc tggccggatt ttcgaccgta gcagcgaatt gtacattatt
    92641 cctgatgtcc gggtattagt ggacgacgat aaaaatgtac aagttatctc aaaccgaaaa
    92701 aatcagccaa atatacgctt tcaagagagt tacttcaaac aaatgtcaca acaagcagat
    92761 aaagaaactg aaaattattt aaaagaacgg aaacaggaat tcgaatggtt gaagaaaacg
    92821 atcctacaac gtggggatac aattttgcgg gttgctcaag tcattgtttc ccggcaaaaa
    92881 gctttcttta tcgacaagga acgtccaatc aagcctctta cgttaaagga agttgcaact
    92941 gagatagatg tgcatgaatc cacggtcagt cgtgcagtca acgggaaata tttggaaaca
    93001 gacttcggtg tatttgaatt aaaaaaattt ttcactacac gaattcctac gaatagtaca
    93061 gaacagacag aagacctttc agcagataca gcgaagaaaa agctgcagga attagtcgat
    93121 caagaagaca aaaacaagcc gttgtctgac cagaaattgg ttgaattgct gaaaaaagat
    93181 gagatagcga tctcaagacg aacagtagca aaatatcgtg atttattagg aatcccgagt
    93241 tcatcaaaaa gaaaacgtta tgataactaa tcagtcaaaa gactagaaaa agtatttcac
    93301 tttttctagt ctttttagtt gaaaaacgag agcaaaactg ttagacttac agtcgtgagg
    93361 ttgagatttc cctttattga tgtgaaattc gaatagttaa tttctttttt tatcgtatat
    93421 gggtcgtttt aagtctacat tggacgtaaa gtgtccaact aaggagatcg ctatgctgga
    93481 tgaaataaaa atgattgaat ctgttgcacc agatattatc gaagtgttgc aagaacgcta
    93541 taaaatttta cgaaatatct attggatgca gccgattgga cgtcgaagtt tatcggaaag
    93601 tatggggatc acagaacgag tattgcgaac agaaacagat cttttgaaaa atctgaattt
    93661 gatcgacacc tcaaaaagcg gtatgacgct gacaactaag ggcgaagaag tttatcaaag
    93721 ccttgaaaac ttcatggatc agcttttagg tacgcatcaa accgaacaac agttggcaga
    93781 atattttggt aaccaacgct gtatcgttgt ttcaggaaac agcgaagagc agaccaaagt
    93841 ggctgatgca ttcggcgaag cgctgagcga agccctagac cgactacttc cagaaggcga
    93901 gaatatcatc gctgtgatgg gaggaactac tatggctgtg gtagccgaac aattgtctaa
    93961 tctggaaaat aagaaacggc ataacctgtt tgtccctgca agaggcggga ttggtgaagc
    94021 gataactgta caggcaaatt ctgtcagtgc aagaatggct gctaaagcaa acggtaacca
    94081 ccgtgcactt tatgttccgg aacaattaag tctggcaact tacaattctt tactcaatga
    94141 gccatctatc caagaagtct taaacttgat tagtgaagcg aattgtgtta ttcatagtat
    94201 tgggcgtgca ttacacatgg cagcacgtcg taagatgact gaaaaagaat tagtcatgct
    94261 gaaacaagca aatgctgttg cggaatcttt tggctacttt ttcaatgaaa aaggtgaagt
    94321 cgtttataag gtccctagaa tcggcataga attgcaagat ttggaaaaag tcccgatcat
    94381 catggcaatc gcgggcggaa aatcaaaagc taaagcaatt cgagcttata tgaaaaatgc
    94441 accaaaacaa acgtggctca tcactgatga agctgctgca aatgagattt taaaaggggt
    94501 aaccctttaa aataaatatt tttttgattt tcataaggag gaaatcttaa atgacagtta
    94561 aagtaggtat taatggtttt ggacgtattg gacgtctagc attccgtcgt atccaagatg
    94621 tagatggaat cgaagtagta gcaatcaacg acttgacaga tgctaaaatg ttggcacact
    94681 tgttaaaata cgacacaact caaggacgtt tcaacggaac agttgaagtt catgaaggtt
    94741 cattcaacgt aaacggaaaa gaagttaaag tattagctaa ccgcaaccca gaagaattac
    94801 catggggcga actaggcgta gatatcgttc tagaatgtac tggtttcttc acttctaaat
    94861 cagcagctga aaaacattta acagctggtg ctaaacgcgt tgttatctct gctcctggcg
    94921 gaaacgatgt tccaacaatc gtttataaca caaaccacga aacattaact ggtaaagaaa
    94981 cagttatctc aggtgcttca tgtactacta actgtttagc tcctatggct aaaacattga
    95041 acgacaaatt tggtgttgtt gaaggattaa tgacaactat ccacgcttac acaggtgacc
    95101 aaatgactct agacggacct catcctaaag gtgacttccg ccgtgcacgc gctgctgctg
    95161 caaacatcgt tcctaactca acaggtgctg ctaaagctat cggtttagta attcctgaat
    95221 tgaacggtaa attagacgga gctgctcaac gtgttcctgt accaacaggt tcattaacag
    95281 aattagtaac agttcttgaa aaagaagtaa ctgttgacga aatcaatgca gcaatgaaag
    95341 aagcttcaaa cgaatcttac ggatacaaca cagacgaaat cgtttcttca gatatcgttg
    95401 gtatgactta cggttcatta tttgatgcta cacaaactaa agtaatgaca gttggcgaca
    95461 aacaattagt taaaactgtt gcttggtacg acaacgaaat gtcatacact gcacaattag
    95521 tacgtacttt agaatacttc gctaacttat aagatagaca aacgtacaag tgtaaattat
    95581 agacatgtac atttaaaagc ggggaagcaa tcgcgcttct tccgcttttt ttgataataa
    95641 gtttattcag gaggaaataa aatggctaag aaaacagtga aagatatcga tttaaaagac
    95701 aaaaaagttc ttgtccgtgt tgacttcaac gttcctttga aagacggcgt gatcactgac
    95761 gacactcgta tcaaagcagc attgccaaca atcaactacg ttctagaaca aggcggaaaa
    95821 gcaatccttt tctctcacct tggacgtgta aaaacagaag aagataaaga aggaaaatct
    95881 ttagctccag ttgcaaaacg tctaggcgaa ttattaggta aagaagtaac attcgtacct
    95941 gaaactcgcg gagaacaatt agaagaagca atccgcaaca tgaatgacgg cgacgttgtc
    96001 gtattcgaaa atacacgatt tgaagatatt gacggtaaaa aagaaagcaa aaatgataca
    96061 gaactaggta aatactgggc ttcattaggc gatgtatttg ttaacgatgc tttcggtaca
    96121 gctcaccgtg cacatgcttc taacgtaggt atcgcttcaa ctggtatccc aacagttgct
    96181 ggattcttga tggaaaaaga aatcaagttc atcggtgaag cagtagaaga accaaaacga
    96241 ccaatgattg caatccttgg tggcgcaaaa gtttctgata aaatcggcgt aatcgaaaac
    96301 ttgattccta aagcagataa aatcttgatc ggtggcggaa tgacttacac attctacgaa
    96361 gcaaaaggaa tcaagatcgg taactctcta gtagaagctg ataaagtgga actagcaaaa
    96421 gaattaatcg aaaaagcagg cgacaaactt gtcttgccaa tcgacaatgt ctgtgcacca
    96481 gaattttcaa atgatgttga aacacaagta atcgaaggag acattcctga tggtttgatg
    96541 gctttagaca tcggcccagc atcagtaaaa ttatttgctg atacattaca aggtgcaaaa
    96601 acagttgttt ggaacggacc tatgggtgta tttgaaatga gtaactttgc taaaggtaca
    96661 atcggtgttt gtgaagcaat cgctaactta gaaggcgcaa caacaatcat cggtggcgga
    96721 gactcagccg cagcagcaga acaattagga tttgctgaca aattcacaca catctcaaca
    96781 ggtggcggcg caagcttgga attgcttgaa ggtaaagaat taccaggact agcagcaatc
    96841 aacgataaat aaacgaccaa gtttgctcaa ttctgacgag taatcgaaca aaaggtgaag
    96901 ggagttttca tgactcccta gccatttttc aataaattaa ggagtgtgtt cctcaatgcg
    96961 taaacctatt atcgcaggta actggaaaat gaacaaaact gcatcagaag caaaagaatt
    97021 tgctgaagca gtaaaaaaca aaatcccttc aaatgacaaa gttgattcag tcatcggatc
    97081 tcctgcatta ttcttacaag aattaatgac atcagctgaa ggtacagaac taaaaatctc
    97141 agcacaaaac tgctactggg aaaactcagg tgcgttcact ggtgaaactt caccagcagc
    97201 tcttgctgat ctaggtgttc attatgtgat catcggacat tcagaacgtc gtgaatattt
    97261 ccatgaaaca gacgaagaca tcaataaaaa agcgaaagct atctttgcaa atggtatgac
    97321 accaatccta tgctgtggcg aatctttaga aacctatgaa gcaggcaaaa ctgctgaatg
    97381 gatcgaagga caaattacag ctggtttagc tgatctttca gctgaacagg tgtcaaacat
    97441 ggttattgct tatgaaccaa tctgggcaat cggtactggt aaatcagctg acgcacaaat
    97501 cgctgacgaa atttgtggag ttgtacgtca aacagttgaa aaactttatg gaaaagaagt
    97561 atcagaagca gttcgtatcc aatacggcgg ttctgtaaaa ccagaaaata ttgctgaata
    97621 catggcaaaa gaaaatgttg acggtgcttt agtcggtggc gcaagcttgc aagcagattc
    97681 attcttgtca ttgttagacg ctgtaaaata attgttgaaa atttgcgaaa aatgcaagaa
    97741 atgtttgcac taatgagcaa aattaactaa aatcgtatat gagggaaatc ccttaggaaa
    97801 aaacaaactc aaaggagaga caaaacatgt caattattac tgatgtttac gctcgcgaga
    97861 tcttagactc acgtggtaac ccaacaatcg aagtagaagt atacacagaa agcggagctt
    97921 ttggccgcgg aatggttcct tcaggtgctt caactggtga atacgaagca gttgaattac
    97981 gtgacggaga caaagctcgt tatggcggta aaggtgtaac taaagctgtc gacaacgtaa
    98041 acaacatcat tgctgaagca atcattggct acgatgttcg tgaccaaatg gctatcgaca
    98101 aagctatgat cgctttagac ggaactccta acaaaggtaa attaggtgcg aacgctattt
    98161 taggtgtttc tatcgctgtt gcacgtgcag ctgctgacta cctagaagta cctttatacc
    98221 actacctagg cggattcaac acaaaagtat tgccaacacc aatgatgaac atcatcaacg
    98281 gcggatcaca tgctgataac tcaatcgact tccaagaatt catgatcatg cctgttggcg
    98341 ctccaacatt caaagaagct ctacgtatgg gtgctgaagt attccacgca ttagcttcaa
    98401 tcttgaaagc tcgcggatta gcaacttctg ttggtgacga aggtggattt gctccaaacc
    98461 ttggttcaaa cgaagaaggt tttgaagtaa tcatcgaagc aatcgaaaaa gctggctatg
    98521 tacctggtaa agacgttgtt cttgctatgg atgctgcttc ttcagaattc tacgacaaag
    98581 aaaaaggtgt ttacgtacta gctgattcag gcgaaggcga aaaaacaact gacgaaatga
    98641 tcaaattcta cgaagaatta gtttctaaat atccaatcat ctcaatcgaa gacggattag
    98701 acgaaaacga ctgggacgga ttcaagaaat taactgacgt attaggcgac aaagttcaat
    98761 tagttggtga cgacttgttc gtaacaaaca ctcaaaaatt atctgaaggt atcgaaaaag
    98821 gaattgctaa ctcaatcctt atcaaagtga accaaatcgg tacattaaca gaaactttcg
    98881 aagctatcga aatggctaaa gaagctggct acacagcagt tgtatctcac cgttctggtg
    98941 aaacagaaga ttcaacaatc tctgatatcg ctgttgcaac aaacgctggc caaatcaaaa
    99001 ctggttctct atcacgtact gaccgtattg ctaaatacaa ccaattacta cgtatcgaag
    99061 accaacttgg tgaagttgca gaatacaaag gtttgaaatc tttctacaac ttaaaaaaca
    99121 aataattctt ttctaatgaa gatacatgat cgactattga aagatagtcg agtatgatca
    99181 cttagttaag taatcgaact ctctacttgc tgaaatatca gcaggtagag agtttttttg
    99241 caactagctt ctgtatatga tgtttacaaa gaatggtaca agaaaagatc atccttgaaa
    99301 aaggaaagct aacaataact agcatcatat aagagctttt aaggatagaa cagtagaata
    99361 ggaatctatg agcaagtcct ctcgtataaa taaaatagga gggaagtagc agcatatttt
    99421 tcataaagtg gctctctttc ttcattttta ctttggttgc tcctatttga aaattcgagc
    99481 acactcaaat acaataaaaa gaaatggcaa gggagaggat tagatgaaaa aagaagaaaa
    99541 aatcgcgatt ttacaagaga tcatccgaat taaatcagtg aatggaaacg aaggtgaagt
    99601 agcagcctat ttgaataagc ttttggcaaa gcatgacata acaggagaga ttgtttctta
    99661 cagagatggt agagataatt tgattgctcg ttaccaaaag ggccaatcag gaaaagtgtt
    99721 aggcctatct gggcatatgg atgtcgtggc ggctggtgat gaatcgtctt ggacctatgc
    99781 accctttgca gcagaaatcc atgggaaccg tttgtacgga cgtggtgcta cagatatgaa
    99841 gagtggcttg gcagcaatgg tgattgccat gatcgaactg aaagagtcag gaaaaccatt
    99901 taacggaaca gtcaaattat tagccactgt cggagaagaa gtgggtgaac taggtgggga
    99961 acagctcacg aaagcaggct atgtagatga cttagatgcc ttgatcatcg gagagccaac
   100021 caattacagt ttgatgtata cgcacatggg atcaatcaac tatacagtca cctcgcacgg
   100081 aaaagaagcg catagctcta tgccagacca aggttataat gcaatcaatc acctaaatga
   100141 attcattacg aaagcaaatg ctgaaatgaa tcacctcgct gaaacaatcg agaatcctgt
   100201 cctaggaaaa acaatccata atgttacatt gatcagtggc gggaatcaag tcaacagcat
   100261 cccaagccat gcgcagctcc aagggaacat tcgatcgatt ccagaatacc caaatgataa
   100321 aatcattgca ttgctgcaat caatcgtcaa tgaattgaat caagagacag actatcattt
   100381 ggaattgatg atcgattaca acaaaatacc tgtcaaagct gatccagatt ctcctttgat
   100441 tcattgcatt cagcaacaat tcagccagcc attaccttta gttggagcgg cagcaacaac
   100501 ggatgcagcc gaatttacga aagctaacca ttccttcgac tttgtcgtct ttgggcctgg
   100561 tgtcgttact ttgcctcatc aagtagatga gtatgttgaa atcgataatt atttggatat
   100621 gatcgaaaaa tatcaaggaa ttattttatc ctacttagcg taagattttt ttaataaatg
   100681 aaaaaacaga gccagattag catt
//
LOCUS       DADVXE010000002        85403 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.002, whole genome shotgun sequence.
ACCESSION   DADVXE010000002 DADVXE010000000
VERSION     DADVXE010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 85403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.002"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            20..93
                     /locus_tag="KB913_000102"
     tRNA            20..93
                     /locus_tag="KB913_000102"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:54..56,aa:Pro,seq:tgg)
     gene            151..224
                     /locus_tag="KB913_000103"
     tRNA            151..224
                     /locus_tag="KB913_000103"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:185..187,aa:Arg,seq:acg)
     gene            360..827
                     /locus_tag="KB913_000104"
     CDS             360..827
                     /locus_tag="KB913_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBB6818499.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            834..3326
                     /locus_tag="KB913_000105"
     CDS             834..3326
                     /locus_tag="KB913_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBB6818500.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            3547..4470
                     /locus_tag="KB913_000106"
     CDS             3547..4470
                     /locus_tag="KB913_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBB6818501.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            4476..5729
                     /locus_tag="KB913_000107"
     CDS             4476..5729
                     /locus_tag="KB913_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBB6818502.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            5863..7209
                     /gene="gor"
                     /locus_tag="KB913_000108"
     CDS             5863..7209
                     /gene="gor"
                     /locus_tag="KB913_000108"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBB6818503.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGIGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(8144..9097)
                     /gene="menA"
                     /locus_tag="KB913_000109"
     CDS             complement(8144..9097)
                     /gene="menA"
                     /locus_tag="KB913_000109"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBB6818504.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9110..10213)
                     /locus_tag="KB913_000110"
     CDS             complement(9110..10213)
                     /locus_tag="KB913_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBB6818505.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(10303..11259)
                     /locus_tag="KB913_000111"
     CDS             complement(10303..11259)
                     /locus_tag="KB913_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBB6818506.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            11540..13474
                     /locus_tag="KB913_000112"
     CDS             11540..13474
                     /locus_tag="KB913_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6818507.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            13931..14347
                     /locus_tag="KB913_000113"
     CDS             13931..14347
                     /locus_tag="KB913_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBB6818508.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            14361..14927
                     /locus_tag="KB913_000114"
     CDS             14361..14927
                     /locus_tag="KB913_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBB6818509.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            14950..15936
                     /locus_tag="KB913_000115"
     CDS             14950..15936
                     /locus_tag="KB913_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBB6818510.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(16091..18073)
                     /gene="scm"
                     /locus_tag="KB913_000116"
     CDS             complement(16091..18073)
                     /gene="scm"
                     /locus_tag="KB913_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBB6818511.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSA
                     SSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSST
                     TSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRA
                     LPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            18360..18884
                     /locus_tag="KB913_000117"
     CDS             18360..18884
                     /locus_tag="KB913_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBB6818512.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            complement(19201..20190)
                     /locus_tag="KB913_000118"
     CDS             complement(19201..20190)
                     /locus_tag="KB913_000118"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBB6818513.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(20326..21132)
                     /locus_tag="KB913_000119"
     CDS             complement(20326..21132)
                     /locus_tag="KB913_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6818514.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            complement(21129..22034)
                     /locus_tag="KB913_000120"
     CDS             complement(21129..22034)
                     /locus_tag="KB913_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6818515.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            complement(22052..23020)
                     /locus_tag="KB913_000121"
     CDS             complement(22052..23020)
                     /locus_tag="KB913_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6818516.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            23748..27365
                     /gene="rpoB"
                     /locus_tag="KB913_000122"
     CDS             23748..27365
                     /gene="rpoB"
                     /locus_tag="KB913_000122"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBB6818517.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            27423..31097
                     /gene="rpoC"
                     /locus_tag="KB913_000123"
     CDS             27423..31097
                     /gene="rpoC"
                     /locus_tag="KB913_000123"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBB6818518.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            31585..32973
                     /gene="ltrA"
                     /locus_tag="KB913_000124"
     CDS             31585..32973
                     /gene="ltrA"
                     /locus_tag="KB913_000124"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBB6818519.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(33058..34632)
                     /locus_tag="KB913_000125"
     CDS             complement(33058..34632)
                     /locus_tag="KB913_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6818520.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(34887..35396)
                     /gene="mreD"
                     /locus_tag="KB913_000126"
     CDS             complement(34887..35396)
                     /gene="mreD"
                     /locus_tag="KB913_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBB6818521.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(35400..36254)
                     /gene="mreC"
                     /locus_tag="KB913_000127"
     CDS             complement(35400..36254)
                     /gene="mreC"
                     /locus_tag="KB913_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBB6818522.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(36409..37047)
                     /locus_tag="KB913_000128"
     CDS             complement(36409..37047)
                     /locus_tag="KB913_000128"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBB6818523.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(37048..37698)
                     /locus_tag="KB913_000129"
     CDS             complement(37048..37698)
                     /locus_tag="KB913_000129"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBB6818524.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(37711..38610)
                     /gene="rsgA"
                     /locus_tag="KB913_000130"
     CDS             complement(37711..38610)
                     /gene="rsgA"
                     /locus_tag="KB913_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBB6818525.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(38775..40844)
                     /gene="pknB"
                     /locus_tag="KB913_000131"
     CDS             complement(38775..40844)
                     /gene="pknB"
                     /locus_tag="KB913_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBB6818526.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(40841..41581)
                     /locus_tag="KB913_000132"
     CDS             complement(40841..41581)
                     /locus_tag="KB913_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBB6818527.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(41594..42952)
                     /gene="rsmB"
                     /locus_tag="KB913_000133"
     CDS             complement(41594..42952)
                     /gene="rsmB"
                     /locus_tag="KB913_000133"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBB6818528.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(42952..43890)
                     /locus_tag="KB913_000134"
     CDS             complement(42952..43890)
                     /locus_tag="KB913_000134"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBB6818529.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(43883..44374)
                     /gene="def"
                     /locus_tag="KB913_000135"
     CDS             complement(43883..44374)
                     /gene="def"
                     /locus_tag="KB913_000135"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBB6818530.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(44389..46797)
                     /gene="priA"
                     /locus_tag="KB913_000136"
     CDS             complement(44389..46797)
                     /gene="priA"
                     /locus_tag="KB913_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBB6818531.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(47050..47355)
                     /locus_tag="KB913_000137"
     CDS             complement(47050..47355)
                     /locus_tag="KB913_000137"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6818532.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(47360..47974)
                     /gene="gmk"
                     /locus_tag="KB913_000138"
     CDS             complement(47360..47974)
                     /gene="gmk"
                     /locus_tag="KB913_000138"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBB6818533.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(48461..48745)
                     /locus_tag="KB913_000139"
     CDS             complement(48461..48745)
                     /locus_tag="KB913_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818534.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(48763..49653)
                     /locus_tag="KB913_000140"
     CDS             complement(48763..49653)
                     /locus_tag="KB913_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBB6818535.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(49673..49891)
                     /locus_tag="KB913_000141"
     CDS             complement(49673..49891)
                     /locus_tag="KB913_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBB6818536.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(49861..51561)
                     /locus_tag="KB913_000142"
     CDS             complement(49861..51561)
                     /locus_tag="KB913_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBB6818537.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            51828..52601
                     /locus_tag="KB913_000143"
     CDS             51828..52601
                     /locus_tag="KB913_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818538.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(52682..53251)
                     /gene="thiT"
                     /locus_tag="KB913_000144"
     CDS             complement(52682..53251)
                     /gene="thiT"
                     /locus_tag="KB913_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBB6818539.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(53317..53419)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(53425..54396)
                     /locus_tag="KB913_000145"
     CDS             complement(53425..54396)
                     /locus_tag="KB913_000145"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBB6818540.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(54490..55863)
                     /gene="glmU"
                     /locus_tag="KB913_000146"
     CDS             complement(54490..55863)
                     /gene="glmU"
                     /locus_tag="KB913_000146"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBB6818541.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(56366..57184)
                     /gene="purR"
                     /locus_tag="KB913_000147"
     CDS             complement(56366..57184)
                     /gene="purR"
                     /locus_tag="KB913_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBB6818542.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(57351..58175)
                     /locus_tag="KB913_000148"
     CDS             complement(57351..58175)
                     /locus_tag="KB913_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6818543.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(58148..58828)
                     /locus_tag="KB913_000149"
     CDS             complement(58148..58828)
                     /locus_tag="KB913_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6818544.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(58851..59789)
                     /locus_tag="KB913_000150"
     CDS             complement(58851..59789)
                     /locus_tag="KB913_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBB6818545.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(60034..60897)
                     /locus_tag="KB913_000151"
     CDS             complement(60034..60897)
                     /locus_tag="KB913_000151"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBB6818546.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(61039..63612)
                     /gene="mprF"
                     /locus_tag="KB913_000152"
     CDS             complement(61039..63612)
                     /gene="mprF"
                     /locus_tag="KB913_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBB6818547.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            63753..64559
                     /gene="proC"
                     /locus_tag="KB913_000153"
     CDS             63753..64559
                     /gene="proC"
                     /locus_tag="KB913_000153"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBB6818548.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(64638..66194)
                     /gene="rny"
                     /locus_tag="KB913_000154"
     CDS             complement(64638..66194)
                     /gene="rny"
                     /locus_tag="KB913_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBB6818549.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(66605..67654)
                     /gene="recA"
                     /locus_tag="KB913_000155"
     CDS             complement(66605..67654)
                     /gene="recA"
                     /locus_tag="KB913_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBB6818550.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(67763..69004)
                     /locus_tag="KB913_000156"
     CDS             complement(67763..69004)
                     /locus_tag="KB913_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBB6818551.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(69244..69822)
                     /gene="pgsA"
                     /locus_tag="KB913_000157"
     CDS             complement(69244..69822)
                     /gene="pgsA"
                     /locus_tag="KB913_000157"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBB6818552.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(70031..70954)
                     /locus_tag="KB913_000158"
     CDS             complement(70031..70954)
                     /locus_tag="KB913_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6818553.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(71693..72979)
                     /locus_tag="KB913_000159"
     CDS             complement(71693..72979)
                     /locus_tag="KB913_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBB6818554.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(72972..74240)
                     /locus_tag="KB913_000160"
     CDS             complement(72972..74240)
                     /locus_tag="KB913_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBB6818555.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            74492..74953
                     /gene="mscL"
                     /locus_tag="KB913_000161"
     CDS             74492..74953
                     /gene="mscL"
                     /locus_tag="KB913_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBB6818556.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(75012..75458)
                     /locus_tag="KB913_000162"
     CDS             complement(75012..75458)
                     /locus_tag="KB913_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6818557.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(75551..75796)
                     /locus_tag="KB913_000163"
     CDS             complement(75551..75796)
                     /locus_tag="KB913_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBB6818558.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(75911..76489)
                     /locus_tag="KB913_000164"
     CDS             complement(75911..76489)
                     /locus_tag="KB913_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6818559.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(76566..77096)
                     /locus_tag="KB913_000165"
     CDS             complement(76566..77096)
                     /locus_tag="KB913_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBB6818560.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(77100..77960)
                     /gene="rlmB"
                     /locus_tag="KB913_000166"
     CDS             complement(77100..77960)
                     /gene="rlmB"
                     /locus_tag="KB913_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBB6818561.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(77953..78348)
                     /locus_tag="KB913_000167"
     CDS             complement(77953..78348)
                     /locus_tag="KB913_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBB6818562.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(78345..79757)
                     /locus_tag="KB913_000168"
     CDS             complement(78345..79757)
                     /locus_tag="KB913_000168"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBB6818563.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(79754..80290)
                     /gene="cysE"
                     /locus_tag="KB913_000169"
     CDS             complement(79754..80290)
                     /gene="cysE"
                     /locus_tag="KB913_000169"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBB6818564.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(80376..80615)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(80612..82072)
                     /locus_tag="KB913_000170"
     CDS             complement(80612..82072)
                     /locus_tag="KB913_000170"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBB6818565.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(82242..83399)
                     /locus_tag="KB913_000171"
     CDS             complement(82242..83399)
                     /locus_tag="KB913_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBB6818566.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(83433..84803)
                     /gene="radA"
                     /locus_tag="KB913_000172"
     CDS             complement(83433..84803)
                     /gene="radA"
                     /locus_tag="KB913_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBB6818567.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(84866..85393)
                     /locus_tag="KB913_000173"
     CDS             complement(84866..85393)
                     /locus_tag="KB913_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBB6818568.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT        24509 a        17579 c        16463 g        26852 t
ORIGIN      
        1 gtctttttta ttttttaaac gggaagtagc tcagcttggt agagcacttg gtttgggacc
       61 aaggggtcgc aggttcgaat cctgtcttcc cgattttttt tatcttgctt tttgttttca
      121 aatgatttat aattttttta aattgaatat gcgcccatag ctcaactgga tagagtgttt
      181 gactacggat caaaaggtta ggggttcgac tcctcttggg cgcgtcgata cggaatagta
      241 tattccgtat ttttttttgt tgattctaaa ggatttattt aacaaaaagc gttcttcttt
      301 ctttctatta tcaaattcgt tataattaag gtcaatatta gtcaaaggga atgaataaga
      361 tggcacatca gaatacctcg gatttaattg aatcatatat aaagaaaatt ctggaaaata
      421 gtgaaatgat cgagattcga aggattgaaa tggcagacct ctttaactgt gttccttcac
      481 aaatcaacta tgtgattaat acccgtttta ccatccaacg tggttatcta gtagaaagca
      541 aacgtggtgg tggtggttat atacgaattg caaaagtaag gatttcagat aaaaaacaat
      601 tacttgagca gataaatcag ttatttgatg atacaatcag tgagaaaaat gcttttgcta
      661 ttattcaaaa actttatgaa gaccaaataa ttacaaaaaa agaaggaaac ttgatgttga
      721 gtgcaattgc aaaaaacaca ttgaatttca atgaatatga agatcataca cgtgctcgga
      781 ttctccgagc atttctggaa cgtttaagtt atgaagatgg gaagtgagat tagatggaag
      841 aactttttac tgaaagagcc caagcagtat tagaaattgc acaagaagaa gcaaaacggt
      901 tgaaacatca atcagttagt tcagaacatg ttttactagc cttagtggtc gagcaaaatg
      961 gaattgctgg aaaagtatta cgtgaaatgg atttgaatga aacggaaatt tatgaagaaa
     1021 ttgaacatct gattggttat ggtggtatcc gttcttaccc taaaggagtc tttcttccat
     1081 attcaccaag aatgaaacaa gtttttgctt tagctagcag cgaagtgaag aaaactggtt
     1141 ctcaaaaagt tggaacagaa catattttga tgagcttatt aaaagatgaa agtatcatgg
     1201 ctactcgaat catgatcaac ttaggtatca gcctttcaaa agcccgtcaa gttctgaaac
     1261 aaaaaatggg gctagctggt gattctgctg gaaaaggaat gaatcgtcgt agaaatgtaa
     1321 atgtacaaga taaacggcaa acaccgcaag gaacacctac gctagattca ttagcacgtg
     1381 atttgacgaa attagcaaaa gaaaacaagc tggacccagt tgttggtcgt tcgagagaag
     1441 tgaaacggct tatccagatt cttagccgac ggacaaagaa taaccctgta ctggtgggtg
     1501 aacctggtgt aggcaaaaca gccattgctg aagggttagc tcaaaaaatc attttaggtg
     1561 aagtgccaga agacatgcaa gaaaagcgcc tgatgatgct tgatatggga tctttggttg
     1621 ctggtacgaa atatcgcggt gaatttgaag atcgaatgaa aaaggtcatc gacgaaatct
     1681 ataatgatgg tcaagtaatc ttattcattg atgaattgca taccttaatt ggtgcaggtg
     1741 gagcagaagg agcaattgat gcttcgaata tcttgaaacc ggcgttagct cgaggagaat
     1801 tacaaacgat cggagcaacg accctagatg aatatcaaaa atatatcgaa aaagattctg
     1861 cattagagcg acgttttgct cgcattcaag tagatgagcc aactcctgaa gaagcagaag
     1921 tgattcttca aggattacgt acaagatatg aagagcacca tggagtggag atcacagatg
     1981 aagctgtacg agcagcagtc aatctttctg ttcgttatat cacttctcgt caactacccg
     2041 ataaagcaat tgatttgatc gatgaatcag cagcgaaagt ccgtttggat caaaccgatc
     2101 acttaacaaa atcaactgtg atcaaactag aaatcgatga actagtacaa gaaaaggaag
     2161 cagcgatcca aaaacaagac tttgaaaatg ctgctcaatt acgcagacaa gaaaaagcac
     2221 tacgtaaaaa gctgcaaaaa gtttctgcaa ttgaagcaaa acaggagcaa ggttattctg
     2281 atcgtgtaac agaagaagat gttgctacag ttgtatcgga gtggactggt gtccctctac
     2341 agcagttgga gaaaaaagaa agcgaacgct tgttagaact ggaaggactt ctgcatgaac
     2401 gtgtcgttgg tcaagatgag gctgtcaaag cagtttcacg tgcgatccgc cgtgcacgaa
     2461 gcggattgaa agatcctgat cgtccaattg gttcattcat gttccttgga ccaactggtg
     2521 tcggaaaaac agaattggcc aaagcacttt cagaagtcat gtttggaagt gaagatgccc
     2581 tgatccgtgt tgatatgtca gaatttatgg aaaaatacag tacaagccga ttaatcgggt
     2641 ctcctccagg atacgtaggg tatgatgaag gtggacagtt gacagaaaaa attcgtcaaa
     2701 aaccatattc agtgattctc ttagatgaag tggagaaagc acatccagac gttttcaatt
     2761 tacttctgca agtattggat gatggtcatt taacagattc taaaggtaga aaagtggact
     2821 ttagaaatac aatcatgatt atgacttcaa atatcggagc gacacaaatt cgagaagaaa
     2881 aaaatgtcgg attcaatgtc caagatgtta ctaaagatca caaagccatg caaaaacgta
     2941 tcttagaaga gttaaagaaa gctttccgac ctgaattctt gaatcgaatc gatgagactg
     3001 tcgtcttcca ttcattgagt aaagatgaaa tccatacaat cgtccaaatc atgagcaaag
     3061 cgattatcaa acgattgaaa gaacaagata ttcaagtgaa aatcacacca tctgcaatcg
     3121 atgtgatcgg gaaagctgga tttgatcctg aatatggtgc acgtccaatc cgtcgcgcac
     3181 ttcaaaaaga aattgaagat cgattgagcg aggctttgct tggcggagaa attcgtttag
     3241 gtgaccacgt aacagtaggt gcttcaaaag gtaagatcac attgaatgtt cgcggaccta
     3301 aaaaggaaac agtaggttcc ctatagttac ttggcctgtg tagctgaatt tttataatag
     3361 taagacttga ttaagaggtt gtgacaagat ttttgtcaca atctcttttt atatttggac
     3421 agaatatatc gaactttatt ttgatttttt gtgaaataat tttcaaaaat ccgactttaa
     3481 atagaagaag tattggaaag tttttagagc tatgctacta ttatgaagtt gtaggaggag
     3541 aaaattatga tcgaactcat aaccacagta gaaactattg aacaagcaga acagttgctt
     3601 gctgcaggtg cagatacact atatttcggt gaagagcaat ttggattgcg tctgcctgct
     3661 tcatttacac gagaagaaca gcgacaattg gtagaattag cacacaagta tggtaaaaaa
     3721 gcgaatattg ctgtaaatgg gatcattcat cctgaaaaaa tgaaaaatgt acctgaatat
     3781 ttggcttttt taaaagaaat aaacgtagat gtgatcacag ttggtgatac aggtattatt
     3841 tatacgatga aaaaaaatcc tgaattgcgt ataccgtata tttatgatgc tgaaacatta
     3901 gtaacgagcg cacgtcaaat caatttctgg gcgaaaaaag gcgcagttgg agcagtactt
     3961 gctcgtgaag ttccttttga agagatgaag gcgatggaag aaaaactcga tattcctgta
     4021 gaaacccttg tgtatggtgc tacatgcatc catcaatcca aacgtccact gctacagaat
     4081 tactataact atacgaaaca agacgaacaa aaagatcgtg aaagaggtct ttttatctcg
     4141 gaacctaaaa aagaagagac acattattct atttatgaag atagtcatgg cacacatatt
     4201 tttgccagca atgatctgaa tctctcgaat gaattgaatg aactttatca gcatcattac
     4261 tgtacatgga aattggacgg attatttact ccaggcgaaa aattcgtaaa catcactcga
     4321 ctattcgccg aagcaaaaaa acaaatttta gaaggtagct gggatcaaga aaaagcggaa
     4381 aaaatgacta gcgaaatcag taaattgcat cctgaaaacc gtgaattaga tacaggattc
     4441 ttttatattg atccttctgc tatcaaataa ggagtatgat gaaagaaatg acagtaaaaa
     4501 gaaaattgaa acgaccagaa atcctagcgc cagcaggaac actggaaaag ttaaaaaccg
     4561 cgatccatta tggagcagat gcagtatata ttggcgggaa tgcatatggt ttaagaagcc
     4621 gtgcaggtaa ttttacttat gaagaaatgg ctgaaggagt tgcttttgca aaagaacatg
     4681 atgcgaaggt atacgttgct gctaatatgg tcacccatga aggaaatgaa gatggagcag
     4741 gggaattttt ccgcagtttg cgtgatgtcg gtatttctgc agtgattgtt tctgatccag
     4801 ctttgatcga aatttgtgcg acagaagccc caggtctgcc gatccattta tccactcaag
     4861 cttcagcaac taattttgag acattggaat tctggaaaga agaagggttg gaacgtgtcg
     4921 ttttagctcg tgaagtttca atggaggaag tggcagagat tcgtaaaaat acggataccg
     4981 aaatcgaagc atttatccat ggtgccatgt gtatctctta ttctggtcga tgcacattgt
     5041 ccaaccatat gtcgatgcgg gatgcaaacc gtggcggatg ttctcaatct tgtcgctgga
     5101 agtatggatt gttcgatatg ccttttggtc aagaacgaaa cagtttaact gatacaggcg
     5161 aagtggaaga agaattctcg atgagtgcag tggatatgtc aatgatcgaa catattccag
     5221 aattgattga aaacggcgta gacagcttca agatcgaagg aagaatgaaa tcgatccatt
     5281 atgtatctac ggtgtcaaat gtctataaag cggctgtaga cagttatatg gaagatcctg
     5341 aaaactatgt ctgcaagcaa gaatggatcg acgagttatg gaaagtagca caacgagaat
     5401 tagctacagg tttttactac aatacaccaa ctgaaaacga acaattattc ggtgaacgtc
     5461 gtaaaatccc agtatataaa tttgtcggtg aagtattatc ttatgatgag gcaacacaga
     5521 ttgctacgat acgtcagaga aacttgtttt ctgtaggaga tgaaatcgaa ttttatggtc
     5581 caggattcag tcatttcagt caaaccgttg aagttatgca taatgaagaa ggcgaatcca
     5641 ttgaccgagc accaaatcca atgatgattt taactatgcc agtcgcacag ccggtgaaac
     5701 ctggagatat gatccgaaaa cgtaaataag gaaaaagctg atatatccct gttttaagca
     5761 tcttcgcata caaaattcaa gaaaagtgtt acacttgttt tctgtagaaa aaggatcgtt
     5821 aaataaaggt tttgattgat ctcttcaata aggaggaaca aaatgcaaat atatgattac
     5881 atcgtaattg gtggcggctc tggcggtatt gcttcagcaa acagagcagg gatgcatggc
     5941 gcaaaagttt tgctgattga agcgaatgaa ttgggcggaa catgtgtcaa cgtcggttgt
     6001 gtacctaaaa aagttatgtg gcaagcaagt acgattttgg aaacaattga acgagatgcc
     6061 tcaagttacg gtatccaagc agatttaaaa aatgttgatt tcgccggtct agtagaaaga
     6121 cgagaaaaat atattgattt tctacacggt gcttatcaaa gaggattaga tagcaatcat
     6181 gtcgaggcta taaaaggtta cgctactttt atcgatagtc aaacgatcga agtaaacggt
     6241 gaaacctatc gtgctcctaa aatcttgatc gctactggag gccgtgcaag taaaatgacc
     6301 attcctggtg gagaatacgc aattgattca aatggatttt ttgaattaac agagttacct
     6361 aagagagcaa tcgttttagg tgctggatac attgcggctg aactttcagg tgtatttcgt
     6421 ggtttaggta gtgaagtcat gtgggcatat cgaaaagaac gaccacttag aacgtttgat
     6481 aaaatgcttt cggacaattt gatccaaatg taccaagaag ctggaataaa aacttacgca
     6541 catcatattg ctaaagaaat tactaaaaac aatgacgaat atacggtgct atttgaaaat
     6601 ggtgaaacct taactggtga ttgtgtactt tttgccggtg gacgtgtacc gaataccgaa
     6661 aaattaggtc tggaaaatac aaatgtggaa ttggacaaaa aagggtttat caaagtagat
     6721 aaataccaaa atacaacgga tgaacatatt tttgctgttg gtgatgtgat cggtaaatta
     6781 gatctgactc ctgttgcaat cgcagctggt agacgtttat cagaacgttt atttaatgga
     6841 aagaaagatt cttatcttga ctataaactt gttccgacag tcgtctttac gcatccacca
     6901 attgcaacaa ttggtttgac agaagaagaa gcattggaaa aatatggcga aaatgaattg
     6961 aaagtttatc gttcacgctt taccccaatg tactttgcat taaatgatta tcgccaaaaa
     7021 tgcgaaatga aattgatctg tgtcggaaaa gaagaaagaa tcgtcggctt acatgctatt
     7081 ggtattggtg tcgatgagat gctgcaaggt tttgccgtgg ctatcaagat gggtgcaact
     7141 aaagaagact ttgacaatac agtagccatc catccaacag gagcggaaga attcgtaacg
     7201 atgcgataat ttaatattaa cagttccaac agctttttat tgaacaaacc atgtaaaacc
     7261 agaaaatcag tatactgatt ttctggtttt ttgtttttta gttatttatg taagattgct
     7321 tcgataattc tcaaaacgaa ataagtaggg aagttggaga ttttgattat cttcgtaact
     7381 gacgaagagt aaatgaatcc atttggtatg cactcttaag ttcaaaatat tggtatcgat
     7441 gtttaaaaga aatagaaatg tatcgaagaa cagatgttta aaaaagtgtg actttgtata
     7501 aataaattag aagaagcaaa cgaggatgtt aaaagaatac catatagtta ccaaaccaag
     7561 aaagttctcg tcaagttcgc tggtacgaat caaatcaagt gaaaaaaggg actgtgaaaa
     7621 aaattgtgtc atagttagtc actttttccg aacaaatagt gttcaatcag ctgtccttcg
     7681 gtattagctc aaaaaacggc aaaatatgag gaactatttt tccatttgtt tctctaatac
     7741 tcaggacaaa acactgattt tacaacctct gataaacggt gttcaaaagc cagtttctcg
     7801 gtattaagcc aaatttatgc aaaaatgtgg aaagccattt tcacaaaatt tttcttaata
     7861 ctcgaaacta agcgactttt tcacaacctc tgataaacgg tgttcaaaag ccagtttctc
     7921 ggtattaagc caaatttatg caaaaatgtg gaaagccatt ttcacaaaat ttttcttaat
     7981 actcgaaact aagcgacttt ttcacaacct cctgataaac ggtgttcaaa agcttgcatc
     8041 tgcggtaata agcccaacca aacgaaaaat ataaggagct atttttattt ggctgttctt
     8101 attacttgat gcagggcagt tttttcacaa cctcttcatg ctgttaaatg gcttgcataa
     8161 tgattgttag taatagcccc aatacataac tggcattgaa taagaccata tttttgatgg
     8221 aatagctgaa actgataggc tggggtaacg tttgcttgaa ttgatccaaa tgcttcttca
     8281 caattggcaa ggtcaagaag gtgaccaaga tcggccattc atagataccg ctcaacaacc
     8341 ccattaaaat cacgaaatag caagcataca tcaatagctg gaataagact gttcccgcag
     8401 gacgtccgat ataaaaaact agtgtatagc gatgattttc aatatcacgg tcaagatccc
     8461 gcaaattatt agccaacatg atattggcaa tcgtaaacac caagggtaag gaagctaata
     8521 cgattgctgc tatagcccaa agatttccta ccaaagcaaa ttgtccagat gaaaagttga
     8581 ctgtcagatc atagacatct gaaccgaatg tattgacata aacgaccatg gcaaaaattc
     8641 caaggcccat agtcacccca ctgaaaattt cccctaaagg cattcgagat aaaggaatcg
     8701 gtccgaatgt atagaatact ccaataaaac aacagataaa tcccatcaaa agtaaaagcc
     8761 aacccgtatt gatcgttaga ataacgccga taacaaaaac aaatgcaatc atagctaaaa
     8821 tcatgtttcg aatcaataca ggagatagat ttctgcggcc aatgacattt tcttcatact
     8881 tatatacttc agaatgagcc ttttcataat ccatgtaatt attgatagcg gtagtcgcta
     8941 aatcaaaaac tagcattcca ataaaaaata aaaaagtgtt tagccaatgt atctcatgaa
     9001 aaaaagcgat agagaataat acccctaccg caaaaggaaa tacactagcc acctttgttc
     9061 gtatttcaac tacttctaaa aagattttta gtgtcatggt tcgtactcct tattttagtt
     9121 cagaacggtc acccatcgtg taatgggagt cctccgataa tttgaaggtg tctttgattg
     9181 gatcggtcac atatacttta tcgtcttttg tcacgaagat cgcttccgtc ccgttattca
     9241 attcgctttc gacgtattcc agtccttttt tcacacccat tgaaaagact gctgtagaca
     9301 acccgtcacc atcaattgat ttatctgtta tgatcgtgac acttgcgata tcattgtcga
     9361 acggataacc cgtttttgga tcaaacaaat gatggtattt tttgccatct acttctaaat
     9421 aacgctcgta aattccagag gtaactaatg ttttgttccg ttctttaata gaacctaaaa
     9481 cagatccgcg agccatgttc ggatcttgga tgccgactgt ccagtcttgg ttttcgcctc
     9541 ttgggctgtg gcctaagaca tagacattac cgcccaagtc aacgatggca gtggtcactc
     9601 cttgtttttt caagactttc actacttcgt ccgtaatgta acctttggcg attgcaccta
     9661 aatcgatgat cattcctttt tcttttagat aaacagtttt ttctttgtca tttagttcga
     9721 tcttatgata atccactaat ttcaatgcct gatcgatttc ttcttgggaa ggttttctgg
     9781 cgtcatcaaa accgattcgc cataattgtg tgattgcacc aatcgccata tcgaatccgc
     9841 cttgagaatc ttggctatat tcgtaggccc gcttgactaa cgtgtagacg tcatcagaaa
     9901 cttttactgg tttgatccca gcttgctcat tcacttcatc gatctcagaa cctttttgat
     9961 tgatcgtgat tttatcacca agttctttta ctcgatcgaa ggcaggtttc aatgctgatt
    10021 ctttgccttc atcatacaca cggatacgaa cgtaagtccc taacaagaac tgttcatcag
    10081 aatatggatc tttcaatatc ttggtagctg ctgaactttc agtggttgtt ttatttgctg
    10141 agttgctgca gccagttagc accataaaag agatgcccag tgtgattaag gaaaatagta
    10201 gttttttccg catctttttc ctctcttcat tttgaaaggt gagacgactg cctaatctgg
    10261 ctatcgtccc accctccaac ttttattagt atgattatgt gattattttt ctgttacgat
    10321 attatctact tcgattgttt gagtgtcgcc tttttcagct gcattcacta attgttgtgc
    10381 gtacatgatg aatgaatgtg agctgtgtgt agcacctgta acaacttcta cattagcagg
    10441 tgagccatct tcttcgccca ttgctttgac gaattcgtcg ttcagagtag ggatgtaagt
    10501 ttttggttct gtaccgcttt ttgctttcat attttcatta tattctgtat catcttgttt
    10561 tgatttaccg tctttgtcga tataatcaaa gtttgattca gttactttgc cgccagcaac
    10621 tgtcatttcg aattgcacac ggtagccgtt agagtagttc ttttcttcaa gcttgtaagt
    10681 gccgtctttc aaatcagcac cattgtcgat ttcgattgta tctgtgttac cagcttgagc
    10741 agcttggatc aattgttgtg cgtagttttg gaagctttca gatgagtgag tagctccagt
    10801 tacgacttcc acaccgcttg cgctttgtgc ttttaagaat tggtcattca actcaggaat
    10861 gtatttttct gggtttgtgc cagattttgc ttccatgttt ttgttgtatt ctgcatcttt
    10921 tgtttttgat tcgccgtttt cattgacgtt atcatatttt gattcagtga ttttgccgtc
    10981 ttttacaacc atttcaaaga ctgcacggta accatttgaa taattttttt cttctaattt
    11041 atatgtgccg tcttgcaaat ctccgccagc tacaactttt gcagatgatt ctgttgtgct
    11101 ttttgcagtc gaagattgtg ctgtagatga ttcagaagaa gagtttgagc ttccgttgtc
    11161 atctgcgccg caagcgccta acactagagc tgaaaatgct aatacggcaa atccagttac
    11221 aaaacgtttt ttcttcattt taatacccca ccattccatt tctagtccac aatttttctt
    11281 tgtgattcat tatacattct aatcttttta gcctataagt caactatttt tgataaataa
    11341 cccatgtaat atttcaaacg ttttctttca gcaaatttcg tgaaaaaacg ctttatttta
    11401 aaatttgaaa aaaatccaaa aggagttaga caaaagaaca gaacatctat ataatatatg
    11461 gagattgtgt aataagtatc aaactaaaag aattatcata tattcattat atagatagtc
    11521 tataaggagc ggatgatcaa tggcaaagca aaatattgtc gttgtaggag caggatatgc
    11581 cggtgtttca gctacaaaat acttggcaaa gaaactgaaa aaagaagatg tagcaattac
    11641 tctgatcgat cgtcattcgt accatactat gatgaccgag ttgcatgaag tagctggcgg
    11701 acgtgtagaa ccagaagcaa tccaatacga tctgcagcat ttgtttgctc gtcaaaagaa
    11761 tgtacaactt gtcacagaca ctgtaatcgg tatcgataaa gaacgaaaaa tcgtcaagac
    11821 caaattaggt tcctatcctt ttgatcagct gatccttgga atgggcggag agccgaatga
    11881 ctttggtaca cctggtgtca aagcacacgg attcaccctt tggtcatttg aagattctgt
    11941 aaggattcgg gaacatattg agaagacagt agcaaaagct gcattggaac cagatgatga
    12001 actgcgtaaa gccatgctga ctttcgttgt ctgtggttct ggatttaccg gtattgaaat
    12061 gattggggaa ctgatcgact ggaaaaatcg cctagccaaa gattataaat tagatccaaa
    12121 cgaaatcaca ctgatggtcg tagaggcaat gccgacgatc ttgaatatgt tggatcgaaa
    12181 tgatgctgca aaagctgaac gctatttgcg taagcacaac gtggaattat tattgaatgc
    12241 accaatcgta gaagtggctg ctgatcatat caaattgaaa gacggacgca acattccgac
    12301 tcacacactg atttggacag ctggtgtcaa aggaacttct gacgctgctg actttggatt
    12361 agaatcagca cgcggacagc ggttgatcgc caatgaatat atgcaggcaa aaggctacga
    12421 agataaaaac atctatatca ttggtgattt agtcttttat gaagaattcc caggaacacc
    12481 gacaccgcag atcgttcaag ctgctgaaca aacaggacac acagccgcag cgaatatcgt
    12541 ggcttcgatc aaaggcggag aaaagcataa atttaaagga aactatcaag gatttatggt
    12601 ttctattggt gccaaatggg gggtagctaa cctatttgat aagatccatt taagcggatt
    12661 tttagctatc gtaatgaaac atatcgtgaa tttgaaatac ttctttgata ttcgttctgg
    12721 ttattatatg ttccaatatt taatgcatga gtttttccat atcaaagatg atcgcaacgt
    12781 gactcgagga cattcttctc gttacggcaa tgtcttatgg agtgtgccac ttcgtatttt
    12841 ctatggttta gtttggttcg ttgaagcttc caaaaaaatc attgggaatg gtgaagtgtt
    12901 caaaccaagt acttggtttg gtgaaggatc atggttcact ggaaacagtg tgttcccttg
    12961 gacatgggaa tacaatgtaa cagatgttgc cagtggtgct tctgctgctg gtgatgcaac
    13021 cacagctgcc agcggagcag gggcaagtgc cggagaagca gcgactcaag ctgcacattt
    13081 tggtttgagt tatgcatacg gtgaagaacc aatggctgtg attgagaagt caccagactg
    13141 gttcacaaag atcatgcaag tgatcatgcc aaacaatgat gtagcaatgt tcttccaaaa
    13201 attcatggta ttctttgaaa ttgccttggc attagcattg attgctggat tattcacatg
    13261 gctatgcagt gcgacaacga ttgtattggt gatcacgttc tgcttatcag gcatgtttta
    13321 ctgggtaaac atttggttca tttttgttgc tttcgcattg atgaacggtt ccggacgtgc
    13381 gattgggttg gatcgctggg taattccatg gctacaacgt acactaggta attggtggta
    13441 cggtagacca agttcccagt acggcaagaa ataaatagat aaagaacgtt atttgaatgc
    13501 aagatttcaa tagaaagggg ctgagacaaa ccgtcacagc ctccttttta tgtaaaatta
    13561 aaggaataag atgcccgaga taagcctcca tgagcaagac acaggtgtca caacctctgt
    13621 tacaacctct tgttataaac ggtgttccag aagtagcttc ttcgaaaaat aagccgaaat
    13681 ttcacaaaaa cttgaaaagt aattttcgta aattccttct tatttcttga agttgcccac
    13741 ttctgtcaca acctcttgtt ataaacggtg ttccacctgc tgcttctcgg taataagccc
    13801 aaagaattag aaaacatgga aagctgtttt ctattcttcg ttcttattac tcaaagcaag
    13861 acacaggtgt cacaacctct tgtttttatg ctaaaattgg gtgagttaat ctggaaaaag
    13921 gagaacaaaa atgagcctta aagaatttgc tgaaaaaagt ctgctcaaac cttgggatgt
    13981 ttttattatt ttgcttttga ctgttctttc ttttttacca gtcatgattt ttggtcttca
    14041 gcaaaacacc gcaacagcag aaaaagaagc ggtactgcgt gtggatggca cagaaatcaa
    14101 aacattccct ttgatggctg gagaagagag caacacatat acttacaaag atgaacacgg
    14161 agattataac ttgatcgaga tagatggcga tcgagtacgg ataaaagaag cagattgcga
    14221 tgaccagatc tgcgtacgtc gaggctgggc aacgaaaaat ggcgaaacca tcgtctgttt
    14281 gccacataaa ttagtgatcg aagtccgttc aacagatgga ggtgacgaag acagtctgat
    14341 ttattagacc ttcacacacc atgagtaaat tacaaaaaat gatttatatt tcgctacttg
    14401 ttgcacaagg agtgatcatt ggtttattgg aaaatatgat cccttatcct ttttcttttg
    14461 cgcctggtgc aaaactaggc ttagccaatc taatcacgat cgttgccatt tttaccatga
    14521 aaaaacgaga cagcttctta ctactttggc tacgactatt cctgactact ttgctaggcg
    14581 gaacgatttc cacattcctt tatagtatga gtggtgcttt gcttagttat tttggaatgt
    14641 tattggtcaa gcaattagga ccaaaacgtg tcagtatcat cggaattagt gcggccggcg
    14701 gtttcatgca taatgtcgga cagcttttga tggcttcttt cattgcacaa tcatggacag
    14761 tcatgttgta cttgccagtc ctttcagttt tagggatttt atcagggatt gcaatcggga
    14821 tcgcagcgaa ttatctttta cgacatgtgc agacacttca acgattccaa aaagattatg
    14881 agcagggaac caaacaaaaa tggagcccaa tgtttaccaa aaaataatcg tcacacaagg
    14941 agttttttta tgaagctaca tccaatgtgg gaaaactatc ctgctttaag taaagaattg
    15001 acagaaacac taaaacggat ggaagaaact gtccgcctga aaaacaaacc tgtcgaacaa
    15061 gcaatcaaag aaacgatcca tgccggcgga aagctgttgc gtcctgccta tcagctattg
    15121 ttctcacaat ttggaccaga gcaagatcga gacaaagcca tcgctttggc agcttctatc
    15181 gaaatgctcc atacggccac actgatccat gatgatatcg ttgatgaagc ggatctgcga
    15241 cgtggtcagc ctaatatccg tagtcagttt ggtaatgtcg tttctgtcta tgcaggagac
    15301 tatttatttg tctgctgttt taaactattg tctgattact ccacttcctt gaaaagtctc
    15361 caattgaatt ctcgcagtat ggaaaaagta ttgaatggcg aattagggca gatggatgat
    15421 cgctataatt atgaactttc tgtaaaagaa tatttggaaa atatttcagg taagacagct
    15481 gaactgttcc aattaagttg ttctgttggc gcttttgaaa gtggaacaag cgagcgcttc
    15541 gcaaaaaaag caggagatat cggactttct atcgggatgg cctttcagat tatcgatgat
    15601 attttagatt atacaaaaga gagccaggaa atcggcaaac ctgtactaga agacatgcgt
    15661 caaggggtct attctttacc gttgatctac tctttgcaaa aaaacaaacc aaagctacta
    15721 ccttatttag agaagaaagc ggcaatgaca gaagaagatg tcgacgccgt acgcaaaatc
    15781 gttgaacata caggaggcgt ggaagaagct aggaagttag cggcctctta cacagaaaag
    15841 gctttgaagg aaataaagaa attacctgcc acctctcttc gaacaaaaga gaatctcttt
    15901 tcccttaccc aactgatttt ggatcgcaaa gactgaatag ggaaaggttc gatacgtaaa
    15961 taaatttctc agaaggaaat ctacgtgttt tttgacaaat tgaattgtag ttcttgtatt
    16021 tatgataaaa agcaaaaata aagagcaacg tccgttagcg acgttgctct tttttatctt
    16081 gaatattttt ttaccttttc gatttcttat aactcataaa agtgattctt aaaccgatta
    16141 caagtaatat aacgcctgcg agtgttatcc aattattcga ttgacttcca gttttaggaa
    16201 gtgctctttt tgatttgttt ccattgtcat tgcttgtttt attagttaag ttaaagttcg
    16261 tcctgttatc cgaacttgtt tttgagaagg agacacttgc atgacgtgta tcgcttgtgg
    16321 tagacgacgt gtctgtacta tcgcttgaag ttgatgaatc tgagctatca cttgtggtag
    16381 aggatgtatc tgtactgtca cttgaagctg acgtgtccgt gctatcactt gtagtggtag
    16441 atgaatctga gctatcactt gtggtagagg tagtatctgt actgtcactt gaagctgacg
    16501 tgtccgtgct atcacttgtt gtggtagatg tatccgtact gtcgcttgaa gctgacgtgt
    16561 ccgtgctatc acttgtggta gaggtagtat ctgtactgtc acttgaagct gatgtgtccg
    16621 tgctatcact tgtggtagag gtagtatctg tactgtcgct tgaagctgac gtgtccgtgc
    16681 tgtcacttgt ggtagaggta gtatctgtac tgtcacttga agctgatgtg tccgtgctat
    16741 cacttgtggt agaggtagta tctgtactgt cgcttgaagc tgatgtatcc gtgctatcac
    16801 ttgtggtaga ggtagtatct gtactgtcgc ttgaagctga cgtgtccgtg ctgtcacttg
    16861 tggtagaggt agtatctgta ctgtcacttg aagctgatgt gtccgtgcta tcacttgtgg
    16921 tagaggtagt atctgtactg tcgcttgaag ctgatgtatc cgtgctatca cttgtggtag
    16981 aggtagtatc tgtactgtcg cttgaagttg atgaatctga gctatcactt gtggtagatg
    17041 tatctgtact gtcgcttgtg tctgtcgtat ctgtaccatt gtcgctgata aatatttcgt
    17101 taggatccca acgattggta gctgcatcta aaatcacatt tgttcctata atcgttccgt
    17161 cttggttttg agtaatgcgg atagtagcat taggcgcaag gattgttcct tgaaaaggag
    17221 cactgattgt caaatcagtc atctcatttc caaaattcca agagatattc gcatccgaaa
    17281 aatcttctgt ttcatgattt gaacgatcat tgtatttgat tggtgactgt acgttcaatg
    17341 cagaagaact gttgatgaca ttaaatacaa ctacttgatc atttggatta atgatttgaa
    17401 gtggcgtatt catcgttaac acttctgcat cgatatttac caataaaaac ccggtatctg
    17461 ataaatcagt taaatcgatt gtccgattgt tcatgtctgg aaaatctgca gcagtatatg
    17521 ttttagctgg agtgatcgtt gcaagatcat ttgctgctac attcaattta gcaaattcct
    17581 gctcgaaatc aatatattca tgcccagcac gatctttata aaaatcatct ggagttaagt
    17641 gatcaagcct ggatccattg actgtaggat gaccatcttg aagtgctaca tccacgttac
    17701 tgccaacgac aaatttattc attcttgtgc tacctgtagg tatgcctgaa gaattagcga
    17761 aagaatcagt tttttgtata taatttattt cttggttcaa taaaccttca tgaagctctg
    17821 taccaaaatt attttttgca tcaagttcat gtgttgctat atttccgtct gtatgtgcat
    17881 tcacagttgt cttattttta gcaaatacgt ggaattgact agcaattcct aacaagccat
    17941 agttaccagt tagatcatta taaatattcc cagggtcttt aggaatgtat gtttccgctg
    18001 aaacggccac accatacgaa aagatattga acaacaaagc aactaggact agtaaacttg
    18061 cccttttttt catttttccc cttcctttcc tttcaaacat tttcctatta tactcttttt
    18121 ctcctagtct taaactgttc gtttgaaaaa tcattgttta tttaaagaat attaatgaaa
    18181 cgttcatatt gttgcttctt gttcaattga tagttcgaca ctatcttttt ctttcaatct
    18241 ccaaactatt gatgatggtg actgttaaag tgtaaaaaat aagggtgtgt agtaacatat
    18301 aagtaggtat cctagaatta ggaaaaagta agtaggataa ataaaaagga ggaaaataaa
    18361 tggattattt agatatgcta tgcgagagtg tggatcgggc atacgatcgg tttgaacgtt
    18421 tgtttgaagg cgtctctatt gaggaggcca atcgttttcc agtggaagat agagccccgc
    18481 agatcaaatc aatgacttgg ctggcttggc ataccgctcg agaattagat ttccagattg
    18541 ctgatttagc aggaacttct ccaatttggc atagtcaaga ctgggaaagc cggtttccga
    18601 tgacgatagc agataacgaa caagattgga agcatagtct ggaacaagca aagcagatcc
    18661 aagctaatca aatagaagat ctgctaggat acttgcgagg agctgctgat tttgctattt
    18721 cttacttaag aaggctggaa ccttccgagc tagatgaagt aattgacgag aactggacac
    18781 caccagtcac acgaggaatg cgtctcgttt ctattattga tgatgctgct atgcactctg
    18841 gtcaggtgat ctatgcgaga cgtttgttgg gattaagaga ttaaggcact agctaaaaaa
    18901 gaacttacgg caaaataagt cgcaagttct tttttgtttt tatcgttacc catggtctat
    18961 ctataagatt gaaaaaggaa gcggcctgct atctcttttg atcgtgtaaa ctgatgactc
    19021 tcttgttttt tgcattgatt catttaaaga aagtgtacca tgctttatag atatttttag
    19081 aatacctttt tctagaggat agagaaactg tcagctgata gaataaggag agtcttttga
    19141 agagaattca gaaaaaagga cactgtatga gatcaggtgt ccttttgtga aatctgataa
    19201 ttattgcgta cggatagatg tgagactgat ttcgccagaa gacaaactca tcttctgttc
    19261 atttgtttgg acgatcagtt cgccatgatc accgatttct tttgcaagac cgacataagt
    19321 cgttcctttt tgattgaacg acacggtttt tcccaatacg aatgattttt ctttatagaa
    19381 gtccaacgct ttttctgggt gagaaagata agtgaacaat tcttgccaga ttttgctgat
    19441 tagctgattc cttgtgacac tagcttgtcc gtcgggaaag acagagatgg ctttttcttg
    19501 gagatcagct ggaaaatgat tttgaggaac agaaaaatta agcccgatcc caatgatgat
    19561 atgactgatc ctgccgcttt ccatatcact gactgcttca gataaaatcc cacagacttt
    19621 ttttccatcc atgtagatat cattgaccca tttgatcgaa gcagaacgac cggttacaga
    19681 ttcaatggct ttcacacagg cactggctgc gatgatcgta tattgaggca attcatcaaa
    19741 ccgtttgtct ggatggagca agagactcat gtagattcct cgtccaggtt cagcgaaaaa
    19801 aggccgtcca aaacgtccac gagcttgttc ttgtgtatca gcaacaaata acttcgaaac
    19861 agaatctcct tgagctgctg ccagtttgac atctttcatc gtagattcag aagtcaacat
    19921 cgtttgtact ttcaaatcag gaataaacga ccgtagctct tgctggattt cttttgcatc
    19981 tagtacgtca gagggcaggt aacgataccc tgtaggcccg tgctcaaaac gatagcctgc
    20041 cttttccaat tctttgatgg ctttccaaat acttgtccgg gaaacttcca gttgctgtgc
    20101 caacttttct ccggaaagaa aatctggtgt ctttttcaat aattgaagta ccttgtcttt
    20161 cgttgtcatg gcatcaagct cctttcccat ccattctatc aggaagaagg agagaacaaa
    20221 atagttttcg aagaaacaac ggttgataca taaagcaaaa acgaaagaag gaaagagaaa
    20281 aaagaagagg gtgggcgttc attttttgtc ccatcctctt tctgattatg aagataaaag
    20341 tacttgatcg tcttttaatg ccgtgccgct gttttgtttg aacaacgcta ataattgggg
    20401 cactgtgagc tgctgttttt cctcttgctg gatatctacg acgatccttc cttgatgcag
    20461 catgatcagt cgactcccat agcggatcgc gtcttccatg tcatgagtga ccataaaagc
    20521 agtgagattc tgctcagtga tcagcttttc tgtcaattcc atcaccgttt tggaagtagc
    20581 agggtcaagc gctgcagtgt gttcatctaa taagatcagt tctggacgct gtaatgtggc
    20641 catcaataac gtaatagctt gacgttgtcc tccagacagc aaaccgattt ctgaggataa
    20701 acgattttcc aaccccaaat ttagccgaac cagctggtct ttgaaaaatg ttcggtcttg
    20761 tggtttgaca ccacggaaga agccgcgttt ttttcctcgt ttcatagcaa gagcaagatt
    20821 ttcttctacc gttaaacgaa cggctgtccc tagtttagga tcttggaata cgcgactgat
    20881 ggatttcgaa cgttcgacaa cagatttttt cgtgatattt tttccattca ataaaatttg
    20941 accctgatcg acagaaaatg taccggcgat gctgttcagc aaagtagatt taccagcccc
    21001 atttccaccg atgatcgtca cgaagtcgcc gggatctaag gaaagattaa tgcctttcag
    21061 gacatgattt tcgttgatcg ttcctttttc aaaggtatga tggagatttt ccaatgttaa
    21121 gacgtcattc atttgacact accgcctttc tttttttgag gtaaatggaa tttttgctgg
    21181 atctgcggga aagaaagaca gatcactagc acgaaagcag aagcaagttt cgaatcactt
    21241 ggttcaacat tcagttcgaa gactaacgct aaaataaaac gataaatgac cgcacctaaa
    21301 acgacagtca agagacggag aaatagtggc tggttacgta acaaaacttc tgcgatgata
    21361 atagaagcaa gtccaattac gatcgttcca ataccagaat ttaaatcagc aaagccgttg
    21421 ttttgcgcaa gcaaggagcc agaaagagca atgcatccat tagaaatcat ataaccgatg
    21481 atcttcatat tatctgtgtt gatcccgttt gcttcgctca ttgccagatt atcgccagtt
    21541 gcacgaatag caagtcctgt ttctgtacgt aagaacaaaa caagtaaaca tacaacgatc
    21601 aaagcaaaaa gcagaccgac gatcagtaca gcgttgtctt ttgttatgcc gaatgactcg
    21661 acccaatgaa agatcgttgg ctgacccaat aaagagatgt tcggcgcacc catcacacgg
    21721 gatgtgacag aatataaacc agtcatggtg atgatccctg caagaagggc gggaattttc
    21781 aattttgtgt gaagcagtcc ggaaacaagc cctgctgccg caccccctaa aaagcctaga
    21841 agacaagctg tcaatggatg atagccattt gtaatactta ctgccgcgat ccctgcacct
    21901 aaaggaaagc ttccttcagc agtcaagtcg gcaatgtcca agatacggaa agtgacgtat
    21961 acaccaatcg caagtagggc ccataagacc ccttgcgatg cagatgataa gaaaagagag
    22021 agcaaatttg tcatgagaat cctcctgtgt tttattcagc ttctttgatg ctgtctggat
    22081 tgatgcctaa tgctttggcc atgtctttat tgacatacag ttccaaatca ttcgctgttt
    22141 cgacaggaag ttcacttgga ttcttgccgt ctaagatttt tgctgccatg atccctgttt
    22201 gtttacccaa gctttcgtag tcgattccta ctgttgctag accgccgtct ttgacttgat
    22261 caactgcgcc agcaacgaca ggtgtttttg tttcttttgc gacttcaccg acaacacttg
    22321 ccgcacttgc gaacgtgtta tcagtaggaa tatagattcc atctacatct ttagctagac
    22381 ttttcgtcac ttgttggaca tcatttgtgg aatttgctgt cagtactttg actttgacgc
    22441 ccgctttttt caattctttt tctgccaaat cagcttggat cttagagttt gcttcaccgt
    22501 tgttatacat gatgccgatt gttttggcgt ctggcacgat atttaacagt aagccgattt
    22561 gtttttcgat tggcaccata tctgtcgtgc cagtcacatt gccgccaggt ttttcattgg
    22621 atgtgactaa atgggcttgt tccaagtctg tgaccgctgt gacagtcatc gggatagtgg
    22681 ttgtttcatt taataaagat tgtgctgctg gagtggcgat tccaagtagc aaatcaggat
    22741 cttctttgac gagtttctca ctcatacttt tcaggttgtc ttgattgttt tgggcatttt
    22801 gataatcgat tgttagatta tcgccttctt tatacccttc ttctgctaat ccttctttga
    22861 atcctttata ggcagcatct aacgagttat gttgtacaag ttgcaatacg ccaattgttt
    22921 tttgtccatc tgatgcctct gcggaattgt ctttttgtgc gcaacctcct aaagctagta
    22981 gcagggcagc gcctaatccg atgattatat tttttttcat ttctttttcc tccttaattt
    23041 tgggaaacaa aaaatccatt cagacaaaat gtccaaatgg attgaaaagt cggaaaataa
    23101 attgaaaaag tagaatgctt gatactttta ctttgtattt tcactgctca gccacttagc
    23161 attttgtcta cgtggctttt tgctgcaata caaagttctt tagccatcat agatacaaac
    23221 tgtcgtttaa cgtttgtatc catcatgatg aatacaaacc tatctaaagt agctaaagta
    23281 aaagttattc agttgtgttg gtgcgatttg gttgatgttg gttcgcatag aagttcctcc
    23341 acaaaatgaa ttttctaaag tataaccgag ataaaaaggt ctgtcaatta agaattgtca
    23401 gataattgaa aacataaaat tgaaaacatt aagaaaatgt tgcgaaaaag cagaagaaac
    23461 gccaggaagt gttgactttt atagaaaata agtgtagtat atgaagttgc aaaaactatc
    23521 tgatgaagaa aaggcagaaa cgaaatattg tccgtttcgg ctttaatata aggaaacaaa
    23581 agtagaagct cacgaagtaa ggtttcaaga gaatgttcta tttttggttt ttttttgcct
    23641 aaaagccgca aaaaatgtct gttgttacct aaaaataata tttgaaatat tattgtaaca
    23701 attgatcggg tagtcttttt gaatgacatt ttagaggggt gaagagcttg gctggacacg
    23761 tagtaaaata cggaaaacat cgcgaacgta gaagtttcgc aagaatcagt gaagtgttgg
    23821 aattaccaaa tttgatcgaa attcaaacag actcttacca atggttctta gatgagggac
    23881 ttagagaaat gtttgaagac attttgccaa tcgatgactt caatggcaat ctatctttgg
    23941 aatttgtaga ttatgaattg aaagaaccaa agtatacagt agcagaagct cgtgcgcatg
    24001 atgcaaacta ctctgcacca ttacatgtaa cattgcgttt gacaaaccgc gagactggcg
    24061 aaatcaaagc acaagaagta ttcttcggtg atttcccatt aatgacagaa caaggaacat
    24121 tcatcatcaa cggggcagag cgagtaatcg tttctcagtt agtccgttca ccaggtgtct
    24181 atttccatgg aaaagtcgac aaaaacggaa aagaaggatt cggttctact gttatcccta
    24241 accgtggagc ttggctagaa atggaaactg atgcaaaaga catctcttat gtacgtatcg
    24301 accgtacacg taagattcct ttaaccgtat tagttcgtgc gttaggattt ggttccgatg
    24361 atacgatctt tgaaatcttc ggcgacagcg aaacattacg caatacagtc gaaaaagact
    24421 tgcataaaaa cgcaagcgac tcaagaacag aagaaggttt gaaagacgtt tacgaacgtt
    24481 tgcgtccagg cgaaccaaaa acagcagaca gctcacgtaa cttgctgaat gctcgtttct
    24541 tcgatccaaa acgttacgac ttagcaaacg ttggtcgtta caaagtaaac aaaaaattag
    24601 atttgaaaac acgtctattg aatctgacat tagctgaaac attagttgat ccagaaacag
    24661 gcgagatcat cgttgaaaaa ggaacagttc tgactcacca agtcatggaa acactagctc
    24721 ctttcattga taatggccta aattcagtga cttactatcc atcagaagac ggtgtggtca
    24781 cagatccaat gactgtccaa gtcatcaaag tattttcacc aagagaccct gaacgtgaag
    24841 taaacgtgat cggaaacggc tatccagaag cagctgtaaa aacggttcgt ccagccgaca
    24901 tcattgcttc aatgagctat ttcttgaact tgatggaagg tatcggcaat gtcgatgata
    24961 tcgaccactt aggaaatcgt cgtatccgtt cagtcggtga acttttacaa aaccaattcc
    25021 gtatcgggct agcacgtatg gaacgtgtgg ttcgtgaaag aatgtcgatc caagatactg
    25081 aaacattgac acctcaacaa ttgatcaata tccgtccagt tgtggcaagt atcaaagaat
    25141 tctttggttc ttctcagttg tcacagttca tggatcaaac aaaccctctt ggcgaattga
    25201 cacacaaacg tcgtctttca gccttaggac ctggcggatt gactcgtgac cgcgccggtt
    25261 atgaagttcg tgacgttcac tactcccact atggccgtat gtgtccgatc gaaactcctg
    25321 aaggcccaaa catcgggttg atcaatagtt tgtccagtta tgcgaaagta aataaattcg
    25381 gatttatcga aacaccttat cgtcgtgtag accgtgaaac aggtcgtgtt actgaccaaa
    25441 tcgactactt gacagctgat atcgaagacc attacatcgt agcccaagca aacagcccat
    25501 tgaatgaaga tggaacattt gctcaagacg ttgttatggc tcgtgctcaa agtgaaaact
    25561 tagaagtatc tattgataaa gtagactaca tggacgtatc acctaaacaa gtagttgccg
    25621 ttgcgacagc atgtattcct ttcttggaaa acgatgactc caaccgtgcc ttgatgggtg
    25681 ccaacatgca gcgtcaagca gtgccgttga tcaatcctca agcaccatgg gttggtactg
    25741 gtatggaata caaatcagcg catgactcag gagctgcttt gttatgtaaa catgacggtg
    25801 tcgttgaata cgttgatgct tctgaaatcc gcgtacgccg cgacaacggt gcattagata
    25861 aatacgatgt aacaaaattc cgtcgttcaa actccggaac aagctacaac caacgtccaa
    25921 tcgttcattt gggtgagaaa gtcgaaaaag gggatactct ggcagacgga ccatctatgg
    25981 aacaaggcga aatggctcta ggccaaaacg ttttagttgg tttcatgact tgggaagggt
    26041 acaactatga agatgcgatc atcatgagcc gtcgtttggt aaaagatgac gtatacactt
    26101 ctatccatat tgaagaatat gaatcagaag cccgcgatac aaaattagga cctgaagaaa
    26161 tcacacgcga aatccctaat gtcggggaag acgcattaaa agatttagac gaaatgggta
    26221 tcatccgtat tggtgcagaa gtccaagatg gcgatttgct tgtagggaaa gtcacgccaa
    26281 aaggggtaac agaattatct gcagaagaac gtctattgca tgcgatcttt ggcgaaaaag
    26341 ctcgtgaagt ccgcgataca tcattacgtg taccacatgg cggcggcggt atcgttcacg
    26401 atgtgaaaat ctttactcgt gaagctggag atgaattgtc accaggcgta aacatgttag
    26461 ttcgtgttta tatcgttcaa aaacgtaaaa tccatgaagg ggataaaatg gccggtcgtc
    26521 acggaaataa aggggttgta tcccgtatta tgccggaaga agatatgcca ttcctacctg
    26581 atggaacacc aatcgatatc atgctgaatc ctttaggggt gccttcacgt atgaacatcg
    26641 ggcaagtatt ggaattacac ttgggtatgg ctgcacgtca gttaggtatc cacgtagcaa
    26701 cgccagtatt tgatggtgca agtgatgaag acgtatggga aacagttcgt gaagccggta
    26761 tggccagcga tgcgaaaact gttctgtacg acggacgtac aggtgaacca tttgatggac
    26821 gtgtgtctgt cggtgtgatg tacatgatca aacttgctca catggtcgat gacaaattgc
    26881 atgcacgttc aatcggacct tactcattgg ttacacaaca accattggga ggtaaagctc
    26941 aatttggtgg acaacgtttt ggtgaaatgg aagtatgggc actggaagct tacggtgcgg
    27001 cttatacttt acaagaaatc ttgacataca aatcagatga cgtagtcgga cgtgtgaaaa
    27061 catacgaagc aatcgtcaag ggtgaaccaa ttccaaaacc aggtgtaccg gaatcattcc
    27121 gcgtattggt gaaagaattg caatcactag gtctggacat gcgtgtcttg gatatcgaag
    27181 aaacagagat cgaacttcgc gacatggacg atgaagacga cgatttgatc actgttgatg
    27241 ctttgacaaa atttgccgaa cagcaaactg ccaaagaatt agaaaagaaa gctgctgaac
    27301 aagtggaaga tgaaaaagac gatgtcatcc aaaactttga aaccgcagaa gataatttag
    27361 actaatccgg tctatgagct gcaaggcggt cgaagatcag ccgtcttgcg gtttgccatt
    27421 aaatgaaatg gagggaaccc cttttgatcg atgtaaataa attcgaaagt atgcaaatag
    27481 gtttggcttc tcccgaaaaa atcagaagct ggtcttacgg tgaagtaaaa aaacctgaga
    27541 cgattaacta tcgtacctta aaacctgaac gcgaagggtt gttctgtgag cggatttttg
    27601 gtcctacaaa agactgggaa tgtgcctgcg gaaaatacaa acgtatccgt tataaaggaa
    27661 tcgtttgtga tcgatgcgga gtggaagtta ctcgttcgaa agttcgccgt gaacgcatgg
    27721 gacatattga attagcagct cctgtttcac atatctggta ctttaaaggg attccttcac
    27781 gtatgggtct tgtattagac atgagcccac gcgctttgga agaaatcatt tattttgctt
    27841 catatgtagt catcgaacca ggaaatacga atttagagaa aaaacaattg ttgacagaac
    27901 gcgaatatcg cgaaaaacgt gaacaatatg gacaagaatt ccaagctgct atgggtgcag
    27961 aagcgattaa acaattactt gataatgttg atctagatgc agaagcagcc gaattgaaag
    28021 aagaattgaa atctgcacaa ggacaaaaac gtacacgtgc aatccgccgt ttggatattt
    28081 tagaagcatt ccgcgcttca ggaaatcaac caagctggat ggttatggac gttatccctg
    28141 ttattccacc agatttacgc ccaatggttc aattagaagg tggacgtttt gcaacaagtg
    28201 acttgaatga tctttaccgt cgtgtaatca accgtaataa ccgtttgaaa cgtttgttag
    28261 acttgaatgc acctggaatc atcgttcaaa atgaaaaacg tatgctgcaa gaagcagtag
    28321 atgcattgat cgataacggt cgtcgcggac gtccagttac tggaccaggt aaccgcccat
    28381 tgaaatctct ttctcatatg ttgaaaggga aacaaggtcg tttccgtcaa aacttgctag
    28441 gtaaacgtgt cgactactca ggtcgttccg ttatcgttgt tggacctttc ttgaagatgt
    28501 accaatgtgg acttccaaaa gaaatggcca ttgaattatt caaaccattc gtgatgcgtg
    28561 agcttgttca acgcgaacta gcttcaaaca tcaaaaatgc gaaacgtaaa atcgaacgtc
    28621 aagaagacga agtatgggat gttttagaag acgtaatcaa ggaacaccca gtattgctga
    28681 accgggcacc tacgcttcac cgacttggta tccaagcatt cgaaccagtt ttagtacaag
    28741 gacgcgcaat ccgtttgcat ccacttgtat gtgaagctta taatgccgat ttcgatggag
    28801 accaaatggc tgtccacgtt ccattgaatg aagaagcaca agcagaagca cgtatgttga
    28861 tgttagctgc tcaaaacatc ttgaacccta aagatggtaa accagttgtt actccttccc
    28921 aagatatggt tctaggtaac tactacttga caatggaaga agaaggacgc gaaggcgaag
    28981 gaatggtctt cagagatcaa aacgaagccg ttatcgcatg gcgcaacgga tatgttcatt
    29041 tacattcacg tatcggtgtg aaccctaact cattaggtga aaaaccattt actgaatggc
    29101 aaaaagaacg tacgatgatc acaacagttg gtaagatcat cttcaacgag atcatgcctc
    29161 ctgaattccc ttatctgaat gaaccaacag acttcaactt gaccgtccaa acaccggaca
    29221 aatactttgt tgaagctggt actgatattc ctgcacatat caaagagcaa gaattagtat
    29281 taccgttcaa gaagaaaaac ttaggaaaca tcatcgcaga agtcttcaaa cgattcaaag
    29341 taacagaaac ttctaagatg cttgaccgta tgaaagactt agggtacaaa cattcgacac
    29401 atgccggtat cacagtaggg atcgctgaca tcagtgtact gaatgaaaaa caagaaatca
    29461 ttgaaaatgc ccataaacaa gttgaaacta ttacaaaaca attccgtcgt ggtctgatca
    29521 cagatgacga acgttatgaa cgtgtcattg ctgtttggaa tgctgcaaaa gacagcatcc
    29581 aacaaaaact gatggaaggt ttggaagcga aaaatccaat cttcatgatg tctgattctg
    29641 gagctcgtgg taacatttcc aactttacac agcttgccgg aatgcgtggt ttgatggccg
    29701 ctcctaatgg tcgaatcatg gaattgccaa tcatttcgaa cttccgtgaa ggactatccg
    29761 tcttggaaat gtttatctca actcacgggg ctcgtaaagg gatgaccgat acagccttga
    29821 agactgccga ttcaggttac ttgactcgtc gtctggttga cgtggcccaa gatgtaatca
    29881 tccgtgaaga agattgcggt actgaccgag gtcttgaaat ccaagccatc cgcgagggaa
    29941 atgaaatcat cgaatcatta gaagatcgtt tagtgggacg ttacacccgt aaagaagtac
    30001 gtcatcctga aacaaatgaa ttgatcattg caggaaacca attgatttcc gaagacatcg
    30061 caaaacaaat cgttgatgca ggtgtcgaaa cagtgacaat ccgttctgtc ttcacatgta
    30121 atacaaaaca tggtgtctgc aaacattgtt acggacgcaa ccttgcaact ggctctgacg
    30181 ttgaagtcgg agaagcagtt ggtacgatcg ccgctcaatc aatcggtgaa cctggtactc
    30241 agttgacgat gcgtacattc catacaggtg gggttgccgg agacgatatc actcaaggtc
    30301 ttcctcgtgt ccaagaaatc tttgaagcac gtaatccgaa agggcaagca gtgatcacag
    30361 aagtaacagg ggatgtcatc gatatctcag aagatcctgc aacacgtacc aaagaagtaa
    30421 caatcaaagg aaaaacagat acacgtacgt atactgttcc ttatacagca cgtatgaaag
    30481 tagcagaagg cgatatgatc caccgtggtg caccattgac agaaggatca atcgatccaa
    30541 aacaattgtt gcaagttcgc gatgtattat ctgttgaaaa ctacttgctt cgtgaagtac
    30601 aacgtgttta ccgtatgcaa ggggtagaaa tcggcgacaa gcatatcgaa gtaatggttc
    30661 gtcaaatgct gcgtaaagtt cgtgtaatgg atccaggtga tacagatatc ttaccaggta
    30721 cattattaga catcgcagac tttaaagatc aaaactacaa tacgctagtc tcaggaggcg
    30781 ttcctgcaac ttctcgacct gtcttactag gtatcacaaa agcatcatta gaaacaaata
    30841 gtttcttatc tgctgcatca ttccaagaaa caactcgtgt cttgacggat gctgcgatcc
    30901 gcggtaagaa agatcctctt cttggtttga aagaaaatgt tattataggt aagatcatcc
    30961 cagctggtac tggtatgcaa cgttatcgtg acatggaacc aaaagaagtc ggtgtagcaa
    31021 gcgaaaatgt ctacagtatt tcagatattg aagcgcaaat ggctgcagaa gacgcaatga
    31081 acaatcaaac aaaatagata ttttaaaaaa gaggttgtga caaattattg tcacaacctc
    31141 ttttttggtg tgcgccctgc atgggtgaaa acttggtggt gaaagtccac tacaggcttg
    31201 gcagtaggaa ctgttagcga aagacaaggc ggcaatcgtg aggttgtggc tgaaggaagt
    31261 cggacgcaaa ctcctgaact gacgaacaga aactagatac aaggctgaat taggtcggat
    31321 aagtcttcat cacaagacaa agtccaatac tgcccgaaac ctatacagta aatctagcag
    31381 ttacatggga ggaaagtttt cactcttacc gggggagatc tcatgagggt gttgtgggcg
    31441 ttgaatgaaa acaaaccagc acaacgatca tggcgacatg atggtgaatc atgagaagtc
    31501 agccgaggtc atagtagtaa cgacactgac cgttacgaag gactgaacaa taagaatctt
    31561 gaataattta ggaggtgtga gaagatgcga cgaccgcaga aaacaagaaa acttggctat
    31621 catcaaagag ctagtgtgga acacgaaggg tatgatgaag tgcgcagcac ttcttgcggt
    31681 gaacagagga aacaagatgg tgtagaaaat ctgtttggga gaattctaga tcggaataat
    31741 ctcaatcaag cgtatcttca agtagtcaga aataaagggg cggctggtgc agatgggatg
    31801 accgtcgatc aactgcttcc ttacttgaaa gagcaccgcg aggaattact atccaattta
    31861 cgccaaggga actataaacc tcagcctgtt ttgcgagtag aaataccgaa accaaacggc
    31921 ggtgtaagaa aactaggaat tcccacggtt attgatcgta tgcttcaaca ggcaatcaat
    31981 caagtgttac aaccgctatt tgaaccagaa ttctcagata atagttatgg gtttcgccca
    32041 aatcgcagcg cacatgacgc agtgaagaaa gcaaaatctt attatgaaca aggttaccga
    32101 tatgtggtgg acattgatat gaaagcctac tttgacaccg taaatcacga taagctgatg
    32161 tatttcattg agcggaaagt aaaggacaaa caagtcctaa aactgatccg tcaatactta
    32221 atgagtggtg taatggaaaa tggactcatc acaacaactg aagaaggaac gccccaagga
    32281 ggcaatctct ctcccctgtt aagtaacatc tacctgaacg aatttgatca agtgctagaa
    32341 aatctaggac ataaatttgt tcgatacgcc gatgactgca atatctatgt tagaagcaaa
    32401 cgagcaggac agcgtgtgat gaagaaatcc attcaatttc tcgaagaaca actaaagttg
    32461 acggtaaatc gagaaaagag tgcggtagga agtccattga aacgaaagtt tcttggattc
    32521 tgcattctgc caacaaagaa aggtattaaa attcgccctc acgcaaaagc aaaacagcgt
    32581 gtgaaaagca agctcaaaca actcactaaa agaaaccgtg gaagaagtat ccaacttatt
    32641 ttaaaagaaa tcaagcaact aatgactggt tggatcaact actatggaat tggtgagatg
    32701 aaagaattca tgagggagtt aaacggttgg ttgaagcgaa gaatcagaca atatatttgg
    32761 aaacaatgga agaatccaag aaccaaaaga aaaaatctga ttcgtttagg gatcgataaa
    32821 gcgaaagcgt atgaatggtc aaatacaaga aaaggtattt ggtcagtctc caaaagtcat
    32881 attcttcatc gatcattaac agacaaagaa ctggcccgcc aaggatatga ggacatctcc
    32941 ttgaagtacc agttcgtaca ctcaacttat tgaaccgccg tatacgggtc cgtacgtacg
    33001 gtggtgtgag aggggcggaa ggtcagttgg ctttcccctc tactcgatta atcattctta
    33061 catgctgaca gcaaagtcag gggcaaacca ttgaactgaa ccaactttta cgctttcgcc
    33121 tggttgagga gcatggatat attgtcctcc gcctaaagca atcgctacgt ggtaagttcc
    33181 gccttgtgac ccccagaata acaagtctcc agcttttgct tgagaaactg aaatttttgt
    33241 tccagctgat tcttgaggaa ctgtccaacc accgatgtca cgaccagtta cttgcatgta
    33301 aacatagcgt gtgaaccctg agcagtcaaa gccacttgga tctttaccgc cccaaacata
    33361 tggagtacca atatatttgt aagcttctgc tacgattgct gcaccattca cacttccaga
    33421 aggagctgga gcaggtgtta caggttttgg ttgttcaggt gttggtgttg gcgttggagc
    33481 cggagtacta cttcctgtgc cgtttcctgt atcaacactt tgatctgttg atggtgttgt
    33541 aggcgcaggt gttgttgatt cttctgttgt tgaagattca ggcactgttg ttgattcttc
    33601 tgttgctgaa gattcaggca ctgttgttga ttcttctgtt gctgaagatt caggcgctgt
    33661 tgttgattct tctgttgctg aagattcagg cgctgttgat tcttctgttg aagattcagg
    33721 tgttgttgat tcttctgttg ctgaagattg tgtagctgat gatgattctt cagtcattga
    33781 agattgtgta gctgatgatt cttctgttgc tgagctttgt gcagtagatg aagcttgagt
    33841 agcttgtgct tcagcctctg cttgttcgcg tgcttctttt tcagcttttt cttgtgcagc
    33901 ttgttgacga gcttgttctg ctagacgttg ttgttcacga atacgagctt gctctgcttc
    33961 agcttctgct ttttgacggt tcaagtcagc tttcttgtct tcagcagttg cttgttcagc
    34021 agctaatgaa gttttcagta cgttcaaatc agcttgttta gataaaagat cgcctttttg
    34081 agattccaaa gcagcttggt tttcagctaa ttcttttagt ttagcatcgt tttcagcttt
    34141 tttgtcttct acagcttttt tatcttgttt ttgttgttcc atcaagtcgt tgtttgcttt
    34201 taccatcgtt gtcattgctt gaacgcgtcc aatagcatct gctaatgaat cagcattcaa
    34261 tacagcatcg atgtagtttg agcttgtgtt gcttacttgt gcttcgcgtg cttgtttttg
    34321 gattgtatct tcacgttttt caatacgttc ttgtaaatct gcaatgtctt ttactaattg
    34381 tgcagattct tgacgcaatg tatcttgttt tgctaatagg tcttgtgctt gtgtgttgat
    34441 ttcagaaact tggctttcta aggcatcgat ttgtgattgt gcatctgctt gttgattttt
    34501 caagtctgca atcttttgat cttgctgttg tatctgagaa tcaaaatcgt ccgccgcggc
    34561 agcgatcggt gatgctacgg cagtcaaggt cattgaacat accattactg ctgatattaa
    34621 actctttttc actcttcatt cctccgactg gcttaattta ataaatatct aaatatattt
    34681 aagtctttct taacgatata aaaattgtac catagcagtg tgtcaacgat ataatagtta
    34741 tgttacaaaa atgtttcaaa acaactttta aaaatgacaa aactgttcgt ttcagaaaat
    34801 gatcatgaaa aagccgcgtt aagtctagca tttcttaaga taacaacgat tctttttcgc
    34861 tttcgaccta aaaataaaaa aagaaattat tcatcactga ataatttctt aaagggaaaa
    34921 atgaataata caaatataat catgttcaac agcagtgtag gtcctaaaaa ccttgtaata
    34981 aaatacgtgt tatttactac tgctaattta aaaatcaact ggaccaccat cgtaaacaat
    35041 tcataacccg tgacaaagat gatcatactg aaaaattcag taaagatgtt gacatggata
    35101 acgtctttca ttacatacat caaccataca attaaaggga gagctactgc atagataccg
    35161 ataacgccaa tatagtaagc gtcatagata gccccgagaa caatcgtggt aatcagtaaa
    35221 taacgttttt caaacgccat actgcaacat aataatgcca atatcagaaa gtgggcattt
    35281 gacatatagg tgcctttcga ccactcccct agcattcttg ttaaatgacc atctatcaac
    35341 atcaaaaaga acaaaacgat tggcagatag tacttcattg tttctttctt caacatggac
    35401 taatcctccg ctagccgttg gacaatcgtc acaactgaca cgtcatacat ttctgcataa
    35461 ggtttcacat aaacttcccg atccagccca taactatctg gtttcgtttt aataaccgta
    35521 ccgatcggca agttagctgg agaattccct ccaagaccgg atgtctggac aacatcccct
    35581 tctttgatat ccgtatcacc agttaattgg gtcaccacta aggcatggag cttttcatca
    35641 tagtttttaa gcaaaccaaa cgcttcgcca ttagccgaag atacccgtac tggaaaatga
    35701 ttggagcttt cattagagga tgacagtaat tcgattttag acgaagccgt attgacctcg
    35761 atcactcggc caatcaatcc tttttgcgac atgactgcca tatttgcttc gataccgtct
    35821 ttagaaccct tgtctacgat cagcatgtcc tgccaactgt caggcgaacg agtaatgaca
    35881 tttgccgtta ctttttcgta actagtcagc gtctgattca actcaagttc ttttttcaac
    35941 gcttcgattt ctctctcgta attcttgttt tgctgtgaaa cgtcatcata gctatcgatt
    36001 ttttctttta gccgctcatt ttcggcataa gttgaaaaaa gattatggac agaatctact
    36061 ccatttcgta cccaccgtac tggggcagag attgttttat caaccattgc aacactgtca
    36121 ttaacgatgg attggaagaa attgggcttt ccttcattcg ctcgctgcgc agcggtcaca
    36181 cttagtatcg tcaccacgat gataacaata accaaggtaa taataatatt tttattagga
    36241 ttgaacttct tcacaaagac acctcgaatt aattagactc ttgtgttcaa ttttatcact
    36301 aaatgccgtg aaacaaaagg taagttgctc ctcttaagct tttttttagc aaataataga
    36361 ttctgtcatt tttagcctga aagacaaatt tttttatttg tttatggatc aatctttgct
    36421 ttgaataact gcaatcatac catctgaaaa agaaaattct gcggtatctg aaagaaattc
    36481 gttacttgca taagatgtcg gatattctac ttctttattt tccaatacat acttgctgcc
    36541 ttttaatgta agattcgaga cgggagtcaa gcagcaataa gctaaatact tcatatctgg
    36601 tatctgtctt actatatgct ctccaggcaa ataataagac aaataatttt gacaatctct
    36661 gataataagc tgatgggcaa agggtttgaa gcgaggttcc atacctaacc agagattggc
    36721 taaaagatga tccaatcttc cgcccgtagc tccaatcaaa gtgacttccg cttgcgggta
    36781 acgttcaaat gtttttaaga tacctaactg tgtatctgta tcgtcttttt ctgcagggga
    36841 acgggtatac tctttggctt ttgcaaatac ttccttctgc tcttcgttcg acaatgaatc
    36901 aaaatcaccc actgccagat ctactgggta gcctgcttga agcaggtaca gcgcaccacg
    36961 gtctatcccg acataggcat cgtatttgga cagcagagac tgcggccagt tttgcggatt
    37021 acctccagca gctaataaaa ttttcattta gtctaatgcc tcttttaatc gttcgatttg
    37081 tccgactgga ttttcggctc catagatata tgatcctgca acgaagacat ccgcccctgc
    37141 atctttacag atttttgctg tttctggaac gattccgcca tctacttcga ttgcataagt
    37201 ccaattgttc tctctacgta gatcagcgag ttccgtaatt ttttctactg tttcttcaat
    37261 aaagctttgt ccgccgaacc caggattgac agtcatgact agtacttgat cagccaaagg
    37321 caaaacatgt ttgatcatgg agactggtgt tcctggattg ataactactc cagctttaac
    37381 tcctaagctt tttgtcattt gaagtgcccg atgaatatga ggagttgctt cgacgtggac
    37441 agtaatgata tctgctccag cttttgcaaa tgctggaatg tagttttctg gatcaacgat
    37501 catcagatgg acgtctaacg gtaatttagt aacaggacgg attgcctgaa caatatttgg
    37561 ccctaatgtg atatttggga caaatcggcc atccattaca tctacgtgga tgtaatctgc
    37621 gcctcctttt tccactaact caatgtctct ttgtaaattg gcaaaatctg cactcaaaat
    37681 ggatggtgct atcttcattc ttgtttcctc ctattttcgt ttaccttctt tttttgcata
    37741 cattggtttt cttttttcga tttcttgtaa gaattgcaaa taattgtcgt aacgtgtctg
    37801 tgcgatacca cctgtttcta ctctatgttt tacttcgcag ccaggttctt tagcatgcat
    37861 gcactctcta aatttgcaat ggacagaagc ttctacaaat tcaggaaatt gtctcggcag
    37921 ttctcctgct tcaattgtca aaaagtcaat cgagctaaat cctggtgtat ctgctactaa
    37981 cccgccatag ataggaatca gttccacatg acgtgttgta tgccgtcctc ttccaagtgc
    38041 atcagaaatc tctcctgttg ctaaattcag ttccggtgat atttgattca gtagcgtcga
    38101 ttttcctgct ccagactgac ccataaagac cgatagccgt tctgggaagt aacggatcag
    38161 ttctgtcgta tcacccgtat gattgggtac aatcaccgga tagcctattt tagtataggt
    38221 ttgcttgatc tcttcgattt tttctgggtc gtctgacaag tcggtctttg tcaaaaaaat
    38281 aatcggttcg atcgactcgt attccaaggt aactagaaag cggtcaagta gattataaga
    38341 aaatgcaggc tctacgatac ttgtgacaat gattccaaga tcaacatttg tgactggtgg
    38401 gcgaactaat tgattttttc tcggcaagat ttccagaaga tagccgtctg tttgattttc
    38461 actctcaaag atcacctgat ctccgacaag cggcgtgatt ttccgattcc ggaaatttcc
    38521 tcttcctctt gtttgatagg tctctccgtt tgcgtataca tagtaaaaac cgctgattgc
    38581 ttttctgatt tgtcctttga taagtgccac ctccgttttt gtttatttta ccatacgaag
    38641 aggaaagtag gtgttattcc atgcaaactt ctcaaagtat atggcttgaa aattgatcaa
    38701 aagagataga aacacaaaaa agagaatgca acaaatcaat gtcgcattcc cttctgatat
    38761 attttattca gcacttattt tgaactttct gaggtgctag ctgatgaact tgtggagctg
    38821 gaagattctt cttttgaaga gttgcttgtg ctactggagc tacttgagct gctagaactg
    38881 tctgaagagt ctttttcaga actagaagac gctggatctg gtcctttaga gtaaattacg
    38941 ttcacaacca ttcctttggt aattgtcgtt cctgcccctg gtactgtacg aatcacttta
    39001 tctttatcca ccgtgtttga atattcggaa gtctcatgcc cgatatattc tgcaccgaca
    39061 ctagctaaat aactttgtgc ttcgcttttt gtatagccgg agatatcatt caatttaggc
    39121 tctgttcctt ggcttacgac aaaattgatg taagtttctt ctgctacaac ttcacccgag
    39181 gctggatcct gactgatgat cgaacctgat ggtacagtgt cgctatagtc ataagtagca
    39241 ctaatattat tgatattgaa tccttgtgta acaagccaat tacgaacagt ttcgtagttt
    39301 tctcctacat gactactcaa agtcactgtt tctggtcctt tgctgactgt gaaagtaatc
    39361 gtgtctgttt taggatcgac ttctgtatct tctgatggag attgcgaaat gatcattccg
    39421 ctttctacct ctgaactgaa ttcctcttct ttttgaatca agtcagcaga aaaccctaat
    39481 tctttcaaac ttgcttcggc atcttcataa cttttaccac tgtaatcatc taatttgatt
    39541 tttttcgtgc cgctactaat atacagagtg acttcgcgtt tttgcttgac tgtcgttccc
    39601 gctgccgggt ctgtcttcac tacattacct tcttcgattt tgtcatctgc aatttcttct
    39661 gtttttgttg ctacttctaa tttcgctttt gcgagtgttt ctctagcaga agcttcagaa
    39721 agatcagaaa catcaggaac aacaacttct cctcgcccgc cagaagcaaa gaatacagct
    39781 gttccgattc ctaaaacagc aagaatagct aataggatca gccaccattt tttctgtcct
    39841 ttctttttag gatcaggcag aacttcttcc tcctctggta aggtttcgtt ttctggcttg
    39901 tcttttggca gaggcataga tttgaatgaa tcaggcattg gtgcatcttc cgtaaggggt
    39961 gtgataactt ttgtttcatt atccatcaca tgaggctgcc atttttcttc gtttgcacga
    40021 gctggtgata atactgtaga aagatcatca gacatttcct cggctgactt ataacggtct
    40081 gcaggttctt tagccgttgc ccgtaaaatc acgttttcca gtgcttgtgg cacatttgga
    40141 tcaagtgctt ttatagatgg aagatcatct tgaaaatgtt ttaaagcaat tgttacagca
    40201 gattcaccat caaacggtac gctacccgtc aacatctcat aaaggatgat ccctaaagca
    40261 taaatatctg actgcttcgt tgccatactt cctctggcct gctcagggga cagataatga
    40321 acagatccta gcatcgtatt cgtctgcgtg atcgatgttt cagataaagc gatagcaatc
    40381 ccgaaatccg tgatttttac aacaccttca ttatcgatca gtacgttttg gggtttcaaa
    40441 tctcggtgga tgatttgatg gttatgagct aaagaaatag cagaaaggat ctgctgcata
    40501 atatttactg ctgtttcata aggaacagga taatgtgttt ggatatatcg tttcaagtcc
    40561 attcctttga cgtattccat caccagatac tgcatgttgt cttcttcacc aacatcgtaa
    40621 acactaacaa tgtttggatg aacgagttct gttgctgcta aagcttctct ctgaaatcgt
    40681 cgaatcgcag tctggtcatt ttgaaagtca aatcgtaaga ctttaactgc tacatcacga
    40741 tccaagatta aatcgtgcgc caaaaataca tttgccatac caccgctacc gatatttcca
    40801 gtgatttgat aacggccatt taattttttg cccaactcga tcatacactg tcctccttat
    40861 attcgataag aagaacggtg atattatccg ctccgcctgc ttcattggca cgatcaatca
    40921 gctcagttac tttatgagac aatgggcctt cttgattgat gatcgttcct atttcttctt
    40981 cagacagcat gttcgtcaag ccatctgaac ataacagcag tcgatctttt agttgccaaa
    41041 gatgagtaga aacatctact tcgactgttc caggcatgcc gacagaacgt gttaaaatat
    41101 ttttccttgg atggttcact gccatttctt cgctgatttc tcctgatttg actagttcat
    41161 tgactaaaga atgatcctcc gtcaattgca tgattttatc ttcacgaatc aaataagctc
    41221 tgctatcccc aacattggca atcgtgaacc agtcatctga cagagcggcc gctacgattg
    41281 ttgttcccat accgttatat tccggctgtt cttgtccacg ctgataaatc agcatatttt
    41341 cttcttgaat cgattgaatg aaccattggg cgattttttc atcgtcaaca gcttcttgtt
    41401 tttcccaagc ttcgcctaga ttcgttaccg ccatctgact ggcaatgtct ccggcacgat
    41461 gaccacccat cccgtctgct aatacagcaa gcttgagacc tgaacggctg gtaaatacac
    41521 tggcatagtc ttgatttgtg ttacgtcgtc ttcctacatc tgattgatat tcaatctgca
    41581 ttttttcacc tcattacttt ttgcgcaaac aacaaatgaa aaatccatct gtgtaaaact
    41641 gatgcggata caaagtcaac attttctctt cgattgatga ttgtagcata ggattggtca
    41701 aaacatcaat cctctcaaaa tcagggtgtc tttccaagaa agcagaaaca acgtcttggt
    41761 tttcttcttt taagatcgta caagtgctat aagtcagaat accggaagac tttaaagttg
    41821 gtgcgcagct ttctaaaatt tccaattgga tttttggtaa attcgctaat tcatccggct
    41881 gttttttata acgaatatct ggttttcgcc gaagcagccc aagacctgaa caaggcgcgt
    41941 ctactaaaat ccgatcaaac tgctctgctt cgaactgttt actgacttct ctagcatcca
    42001 tcttttgagc gtagacagca gaagagacac ctagacgtgc tgcattatct tcaatgagtt
    42061 tgactttgtg ttcgtgtaca tctaaagcga ccacttctcc accgcatgac ggatctaaaa
    42121 aagaagcaat atgcgtcgtc ttacctccgg gtgctgcaca ggcatctaag acatgatgtt
    42181 caggctcgat ttgcatagac ggcgctacaa gcatcgaact ttcatcttgg atcgtcatga
    42241 cgccatcgtg gaacaatgag ctagaagcta aatgcccttt tttcgctact ataccgtatg
    42301 gactgacttg gcttttttca gctgtgatct cttcttcttg caaaacagtg atggcctgat
    42361 ctctggaaag tcggcgtgta tctactcggg cactagcatg gctaggctga tatagcgata
    42421 aaccgagctt ttcagtttct tcgtatccga tttgatccac cagtcgtttc gtcatccata
    42481 gaggcaggct gattttgaca gaaagtcttt cgataggatc agcaatgcct tgcagatctg
    42541 gtgctccttg acgctgataa ttcctcaaga caccatttac aaatttccct gtcccaggat
    42601 ttccttttac ttttgcgatt tcgaccgcct cgtttaaaat agcatgtgca gggactttat
    42661 ctaaaaattc taattggtat acagaaagat aaagaagcat cttgacccag tcatccactt
    42721 tttttgcttt agcgatcaat ggtgcaacgt aaaattccaa tagtcgctga tggctaatcg
    42781 taccatagat caattctgta aataaaccca catctttttg atttagctcg ctttgtttga
    42841 tcatctcatt caacaaaaga ttcgagtagg cgccaccctt gttcactcgc tctaatgtca
    42901 gtaatgccat atatcgtact gattttttca tttttttagg gatttttttc attatttcac
    42961 ctgctgacca atctgaactt gctgaccgct tccgttaagg aaatcatgta cggcctgttt
    43021 tcctttacca gctggctgta attcattgat ggctaagacg gtctgtttac cgcaagcaat
    43081 ccatagattt tttttgtctt tccggatgat cgtaccaggt gctttgtctg tagtttctgc
    43141 caatacttca accgataata atttccagcg tatgccctca taggtcgtga atgcaattgg
    43201 ccaaggacgc attccgcgta cttggttgtc aatttcttct gcagttttat gccaatcgat
    43261 tgcttcttgt tcccgtgtga tgtttggcga aaaagttgct tctgactcgt cttgaggtac
    43321 tggtttttgt ccatccaaaa tattgggcaa tgtttctagc aatagctttc ttcctaaaag
    43381 gctaagcttt tcaaacatcg tccctacatc atcttgttta gtgattggta tgctttcttg
    43441 cgcatagatt ccgcctgcat ccattttttt gatcatttcc atgatcgtta caccagtttc
    43501 tttctcccca ttcatgatgg cataatgaac aggcgcacct ccccgatatt taggaagtaa
    43561 agaagcatgg acattgattg cccctaattt tggtacttgc aataactttt caggcaagaa
    43621 ttggccaaat gccgcagtga cgatcacatc aggcaccaat tcaatgattt cttccatttc
    43681 tggcgaaccg gagattttct ctggctgcag cacacggata ccgtgcttca gagccgcttt
    43741 ttttaccggt gtcggcgtaa ttactcgttt ccgcccaact ggacggtcgg gctgtgttac
    43801 cactgcctgg atctcgtaac ctgattctat cagcccttca agaatcggca cagaaaaagc
    43861 aggtgtgccc ataaatacta gcttagtcat caagatgttc ctccatatat tcttcaagtt
    43921 cttcttccgg gatctgctgt atcattttct caatgaacaa gataccgtct aagtgatcga
    43981 tttcatgctg gaaggcacgg gctaaatagc caaaagccgt cacttctatc tcttctccgt
    44041 ctcgatcata ataacgcacg gtcacttcat ctgctcgctt gaccgttcca tagacatgcg
    44101 gaatactgag acaaccttct acgtcaaggc tttcaccttt tgcttcgatg atttctgggt
    44161 taatcagttc aaatttctcg ccttcatcta cttcgatcac agcaattctc ttgttttgtc
    44221 ctacttgagg agcagcgatc cctattccgt cattcgcaat cattgtctca tataaattgt
    44281 ctaataaagc gattgtctcg tccgtgatta catcgattgg ctgagcagtt ctttttaatt
    44341 tatcattagg gtggatcaat ataggatagc gcataatttg gccctttctt aaataaagtt
    44401 taatggttcg ttgtcaattg ccacaaaaag accttgtcgc tgttctttct ggcttccatt
    44461 caaaatttca tccaaaacat gaggaagatt cggttcatgt ttatatttga tgattagttg
    44521 ataataatat cggtttttca ctctcaaaat catgctgggc gttggcccta atagcaagct
    44581 ttgagggctt aacacttctt ttagctgatt ggcaatctga aagattttct ttgccgctac
    44641 ttgttcttca ggatggctgg cggttatttt cacagtaaag taataaggag gatagcctcc
    44701 acgatgccgt acatgcattt cctgctgata aaactgctca taattttgtt ttttagccaa
    44761 ttctatggcg taatgttgag gattgaatgt ttggatcacg acttcgcctg ctttttccgc
    44821 tcgccctgct cgtcctgaaa cttgggtaag caattggaat gtatgctcac tagaacgaaa
    44881 atccggtaaa ttcagggagg tatcagcatt caacacccca actaatgtca cttctggaaa
    44941 gtccaaacct ttagcaatca tttgtgtccc taataatata tctgcttctt ttgcaccgaa
    45001 tttttgtaaa atctgttcgt gtgccccttt tcttcgagtg gtatctacat ccatacgcaa
    45061 aatcctagct tgcggataaa gttctcggag ttcctcttct actttttgag tacctgttcc
    45121 atagtagcgg attttattgc cgccacaatt aggacagcga ttgggaatag gttcttcatg
    45181 tccgcaataa tggcagcgca ttgaacgtgt atccatatgc agtgtaagag agatatcgca
    45241 attaggacat ggaagaacaa atccacagtc cctacacatc acaaaagacg aatatcctcg
    45301 acgattgagc agtaggacag tttgttcttt tttgtctaat cgattttgta ttttttcctg
    45361 caaattagca gaaaaagtag aggtccgatg attctgaaac tcttcacgca tatctacgat
    45421 ctcaatagct ggaagctgtg cagctgcttt ggctcggtgg tttaactgca ataactgata
    45481 aacgcctttt tgagctcgtg ctcttgattc taaagagggc gtcgcgcttc ctagaactat
    45541 tgggcaatga tgatatttac tgcgccaaat tgctagatct ctcgcatgat aacgcggtgt
    45601 ctcatcttgt ttgtaacttg attcatgttc ttcatcgata atgatcagcc cgatattttt
    45661 cagcggggca aaaatagcag atcgtgcgcc tactactact tgcgcttctt cccgctcaat
    45721 cttgcgccat tcatcatatt tttcaccttg ggaaagtccg ctatgtaaga ccgcaactga
    45781 ttctccgaag cgtcctttga atcgctcgac catttgcgga gtcaatgcga tttcaggcac
    45841 taacataata gccgttttat tttctgacaa aacatcagcg attgcctgaa gatatacttc
    45901 tgttttcccg ctgccagtga ttccctccag caaaaagacc tgatcttttt gctgctgacc
    45961 tgctgtgatg atttgttcga cagcattttt ttgttctgca ttcagttcca atgccgtcgt
    46021 ttggtcaaat actcggtctt tataagggtc gcgataacgt tctgattcta taaactccag
    46081 ccagcccttt tcttttcctt gattcaagac agcagtactg attcctttat ttttgaaata
    46141 agcaattggt tcttcttggc tcagttcaga taaacacaaa agaagttctt tttgtttctt
    46201 ggcattttgc cgtaattttg cccattcttc ttcgatttgc ttttcagtta acaaagaacg
    46261 gaccaaacga atcgttttta ctttatttcg tgtatggact tcatatttga tatctactaa
    46321 ttgctcttgg cgccagcgaa tcaattgaga aaggctgcct tcttcttctg cttccttcca
    46381 ggaaatcact tctcgctgat caaacaatac ctgaacttct ggtgtgtctg ccaaaggata
    46441 gatcaattta tcatattctg ctttcatcac actcggaagc atcgtttgta gacaagtgat
    46501 tttgaatgcg taagtaattt ttttcatata atcagctaat gaaagtaatt cttcattgac
    46561 caccggagca aggtctagca aacgaataac tgccttcaaa gatggattag ctgattcttc
    46621 tgatttttgg atagccataa caaatccttg gacatgacga ttgccattac caaaagggac
    46681 ttctactcgc atcccgactt gcaaagctgt ttccatttca gagggaacca aataagtgaa
    46741 tggctgatcg gtctgcatag taggtacgtc cacaatgact tcagctgtta atgtcatggt
    46801 tcgtttcctc ctttttttgt cttttcttat caagcgacaa aaagttcctt gcctatttta
    46861 ctagagatcg atggatttgt cttatcttct gccaaatcct aacaaaaaat taacagcaga
    46921 taagaaaaaa aagaactgtg tcaaaaagtt cagacacagc cttttctacc agacaataag
    46981 tggcgaatgt ttgaaaagga aacagctggg tttgcttttc tttttagatg ttcgctctat
    47041 ttttctttat tacatttttt gctcttcacg gatacgtgat tccaattcgt gttgttcacg
    47101 ctctttttgt gcttgacgtt cctcttcttc catcttcaaa cgttcacgtt ttaattcagg
    47161 atgtggatca ttgactacat ttcctgcatc gatttcttct aaagcttgac cgacgctttt
    47221 tactgaatca aaagaatcta gagtaggctg tgcacttgca tccaattcat gcgcgcgttt
    47281 acttgctaaa atcactagag aatattttga atttacacga tctaatagtg agtcaattga
    47341 aggttttaac atcataagac tacatctcct ttaacatttt aatatattta ccgattacgc
    47401 gatctactcg aaaatgttca ctggcaataa tgtttttgat tcgttcaact gctagcggca
    47461 cttcatcatt tacaacagca tagtcgtaaa gagccatcat ttcgatttct tcttttgcaa
    47521 ctttcattcg tttttcgatt acttcatctg catctgttcc tcggcctacg atccgtgatt
    47581 ttaattccgc taaatctggc ggagtcaaaa agatgaatac accatcgggc actttttctt
    47641 tgacttgttt tgctccttgg acttcaatct ccaagaaaac atcttttcct tcatccaatg
    47701 tcttgttgac atatgacaaa ggagttccat aataattccc gacatattct gcgtattcca
    47761 gcatctctcc agcttcgatc attgattcaa actcttcttt gcttcggaag aaataatcaa
    47821 cgccttcgac ctccccttca cgcattttac gggtagtcat tgagatcgaa tactgaaaat
    47881 cattatcctc actctcaaaa attgcttttc gtactgtgcc ttttcctaca ccggatggac
    47941 cagacaacac gattaataat ccacgctctg acatgacgac gtcctttcaa ctagtctttt
    48001 tgtacttatc gtttattttg cacttttttt ctgcaacttt caaggttatc tttaattata
    48061 gctagaaatt ggtaaaaaag ctaccctgta ccaagaggtc gtaaaaaagc tgtcctgcat
    48121 caagtaataa gaacagccaa acataaacag cttctcatgt ttttcgtttg gttggggtta
    48181 ttatcgcaga tgcaagcttt tgaacgccgt gtataagagg tcgtgaagaa gccgattagt
    48241 ttcgagtatg aagaaaaatt ttgtgaaaat agtttctcac atttttgcat aaatttggct
    48301 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
    48361 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
    48421 attctgttta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
    48481 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
    48541 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
    48601 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
    48661 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
    48721 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
    48781 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
    48841 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
    48901 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
    48961 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
    49021 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
    49081 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
    49141 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
    49201 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
    49261 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagca cgaagcgttc
    49321 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
    49381 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
    49441 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
    49501 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
    49561 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
    49621 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
    49681 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
    49741 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
    49801 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
    49861 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
    49921 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
    49981 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
    50041 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
    50101 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
    50161 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
    50221 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
    50281 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
    50341 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
    50401 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
    50461 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
    50521 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
    50581 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
    50641 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
    50701 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
    50761 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
    50821 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
    50881 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
    50941 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc tttttccata aattcacagc
    51001 ttttttcata tctccttgta aaatcaatgc gccgttcaac gcacctaccg aggtacctgt
    51061 gataatctca aagttgatat catgttcctt cagcgcctgc cacacaccaa tctgataagc
    51121 accgtgcgct cctcctccac ctaaaacaag tgctgtatga tagaccagct ttttatttaa
    51181 ttgtgtggtt ccttgatagc cgtttttatg aaaaatacgc aaccattctt ctgatagagg
    51241 agattgaaat aaaaaacaac agttttcttt aataaaaaaa cgagcgcaag cttccatata
    51301 ccgaaaaaat tttttccatt caaaagtttc accttcaatc aacagattat taaaaataac
    51361 atctcctcta cttttagcaa tagtaaaata gacggtatat tttttcgata ctgctttaaa
    51421 agcacattgc ttttttgcag aacgccaaaa agcgtctcta ctttcttgat gactttgaaa
    51481 aaatggaagg ggttgttttg cttgctggat aggcgaatac agcgacattt tctgtgaaaa
    51541 gtaaactttt tttatctcca tcgcgctctc ctttttcttc aagtatacca gtacgtcata
    51601 aaaaggtcat gagtctcgta ttcgactttg tagattccat aagaaaacaa ttcataaaac
    51661 ctcctttaaa taaaaaaata caaaaatcac aaaaattaat tgaaaatgag agtgttttca
    51721 atgaaaacgt gattttgtaa tggaatttta aaataaaaga aacaagcttt tttaatgcaa
    51781 atgttgtaaa ataaaagaga ttaagaggaa ataagaggag gaacatgatg actgagtcag
    51841 tttatgtaca tattgatacc acaagtaatg ctgttttaac aaaagggctg actgctactg
    51901 actttgcaaa cagtatcgtg cattttcctc aaaacttgct cttgcttgat ccatctgctt
    51961 ctgctggaga atatgaatcc catacagggc tgaaagtaat ccgtggtaca gaaaatattc
    52021 agcgtttctt ttcctcttct cgtaacaggc gtggattcga tgaattgaag tggatcgact
    52081 ttactgattt aacgatgctg aaagaattga cacctttaga aatttcagaa ttattatatt
    52141 ttggtcatat gaaaacacat cttcattcgc cgttttttta taaactacag aataattttg
    52201 tatacttcga tcttaatgat cagctgaatc ggatttatta tcgctattta gatgaatttt
    52261 ataggatttt tgctagtaaa ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat
    52321 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
    52381 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
    52441 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
    52501 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
    52561 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
    52621 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
    52681 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
    52741 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
    52801 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
    52861 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
    52921 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
    52981 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
    53041 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
    53101 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
    53161 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
    53221 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
    53281 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
    53341 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
    53401 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
    53461 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
    53521 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
    53581 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
    53641 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
    53701 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
    53761 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
    53821 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
    53881 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
    53941 catcaaatga tcgactggaa tatcaaagaa accttggatt tggactgcat gaaggtccaa
    54001 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
    54061 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
    54121 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
    54181 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
    54241 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
    54301 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
    54361 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
    54421 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
    54481 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
    54541 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
    54601 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
    54661 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
    54721 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
    54781 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
    54841 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
    54901 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
    54961 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
    55021 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
    55081 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
    55141 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
    55201 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
    55261 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
    55321 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
    55381 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
    55441 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
    55501 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
    55561 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
    55621 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
    55681 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
    55741 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
    55801 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
    55861 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
    55921 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
    55981 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
    56041 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
    56101 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
    56161 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
    56221 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
    56281 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
    56341 aactaagcgg ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
    56401 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
    56461 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
    56521 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
    56581 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
    56641 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
    56701 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
    56761 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
    56821 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
    56881 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
    56941 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
    57001 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
    57061 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
    57121 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
    57181 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
    57241 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
    57301 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
    57361 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
    57421 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
    57481 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
    57541 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
    57601 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
    57661 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
    57721 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
    57781 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
    57841 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
    57901 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
    57961 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
    58021 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
    58081 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
    58141 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
    58201 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
    58261 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
    58321 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
    58381 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
    58441 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
    58501 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
    58561 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
    58621 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
    58681 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
    58741 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
    58801 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
    58861 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
    58921 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
    58981 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
    59041 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
    59101 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
    59161 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
    59221 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
    59281 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
    59341 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
    59401 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
    59461 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
    59521 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
    59581 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
    59641 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
    59701 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
    59761 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
    59821 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
    59881 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
    59941 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
    60001 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
    60061 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
    60121 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
    60181 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
    60241 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
    60301 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
    60361 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
    60421 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
    60481 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
    60541 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
    60601 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
    60661 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
    60721 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
    60781 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
    60841 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
    60901 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
    60961 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
    61021 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
    61081 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
    61141 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
    61201 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
    61261 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
    61321 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
    61381 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
    61441 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
    61501 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
    61561 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
    61621 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
    61681 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
    61741 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
    61801 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
    61861 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
    61921 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
    61981 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
    62041 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
    62101 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
    62161 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
    62221 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
    62281 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    62341 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    62401 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    62461 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    62521 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    62581 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    62641 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    62701 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    62761 aactactgct acatcttgcc gaacagacaa ttgactcatt cctaagatca tcaaaacgtc
    62821 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    62881 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    62941 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    63001 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    63061 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    63121 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    63181 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    63241 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    63301 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    63361 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    63421 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    63481 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    63541 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    63601 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    63661 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    63721 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    63781 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    63841 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    63901 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    63961 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    64021 tcatttctat tgcttcagga aaatcattaa tagatttaga aacagcgctt gaagatcctc
    64081 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    64141 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    64201 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    64261 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    64321 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    64381 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    64441 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    64501 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    64561 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    64621 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    64681 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    64741 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    64801 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    64861 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    64921 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    64981 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    65041 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    65101 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    65161 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    65221 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    65281 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    65341 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    65401 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    65461 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    65521 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    65581 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    65641 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
    65701 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    65761 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    65821 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    65881 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    65941 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    66001 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    66061 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    66121 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    66181 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    66241 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    66301 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    66361 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
    66421 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
    66481 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
    66541 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
    66601 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
    66661 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
    66721 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
    66781 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
    66841 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
    66901 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
    66961 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
    67021 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
    67081 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
    67141 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
    67201 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
    67261 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
    67321 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
    67381 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
    67441 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
    67501 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
    67561 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
    67621 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
    67681 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
    67741 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
    67801 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
    67861 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
    67921 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
    67981 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
    68041 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
    68101 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
    68161 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
    68221 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
    68281 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
    68341 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
    68401 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
    68461 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
    68521 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
    68581 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
    68641 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
    68701 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
    68761 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
    68821 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
    68881 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
    68941 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
    69001 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
    69061 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
    69121 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
    69181 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
    69241 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
    69301 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
    69361 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
    69421 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
    69481 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
    69541 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
    69601 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
    69661 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
    69721 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
    69781 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
    69841 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
    69901 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
    69961 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
    70021 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
    70081 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
    70141 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
    70201 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
    70261 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
    70321 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
    70381 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
    70441 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
    70501 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
    70561 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
    70621 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
    70681 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
    70741 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
    70801 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
    70861 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
    70921 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
    70981 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
    71041 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
    71101 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
    71161 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
    71221 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
    71281 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
    71341 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
    71401 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
    71461 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
    71521 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
    71581 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
    71641 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaaatactg gtttattttg
    71701 gtctcatgta aaactcgctg aaggcctctt cacttataaa tgcttcccca gctgccagta
    71761 cgtctttcat ttggatcgaa tcgatgattt caggaagatc aaataaagtt cgatcgccaa
    71821 ataaactttg cgtaaattga ttggcaatat attcgatcga atttaatgat tggaaatatt
    71881 gtccaagcat tttcttcttc agcaaatcga gatttgtttc tgacacttcc ggatcatcag
    71941 cgaatccaag aatgatttct ttgacttttt ctgctgcttt ctctggttcg tccgtatctc
    72001 cgctgaagtc cgcaaagtga aattcacgat ccaagctgaa ttcaaaacca aagctgtcat
    72061 cgataattcc ttgattgtac atcgctagat agtttcgaga agtattgcct aaaatcattt
    72121 ggaacaacag attgattgct gttttatagc gtaacagttc tgttccttct tgcggcaatg
    72181 tgtctaatcc tttaatacca agtacaaatt tatctcgtgt aatggctgct tccaatgcac
    72241 tttgtttgat gatttctttt gtgttttcag ggaaataacg tacaatttct tgctttggag
    72301 ggaaattttt tgcttcttgg ttttcccgaa taagtttcat caatttctca ggctccatct
    72361 taccaactac aaataaaacc atattgcttg gctgataaaa cgtccgatag cacgtataca
    72421 agtcttgagc tgtgattttg tcgatacttt caaccgtgcc cgcaatatcg atatgcaatg
    72481 ggtgtgtagg atacaagtta tttagtatgc caaaaaacat ccgccagtta gggtcgtctt
    72541 catacatttg gatttcctga ccgatgattc ctttttcctt gtttacagtt tcttctgtga
    72601 agtaaggtgc ttgtacaaaa tcgatcagag tcgtcagatt cttttctacc tgatccgtcg
    72661 tagaaaacag atagctggtt ttcgtaaaac ttgtgaaagc attggcggaa gctccttgtt
    72721 tcccaaataa ttgaaagaca tcaccatctt ctttttcaaa caacttatgt tctaaaaaat
    72781 gggcaattcc atctggaact ttcacctttt ctttttcacc atagggaata aattcgttat
    72841 cgatcgaacc ataattcgta ctgaacaaac catatgtctt gtgatagtca tttttaggca
    72901 acaaatacac ggtcaaaccg tttggcagta cttcatgata aagtgtttca ttgatttgct
    72961 catattctgt tttattcatt tgcatttcct cctgctaaaa agaagattgc ctgcaattcg
    73021 atttgctcag ctacttgttg tatctctttg atcgttacgc tctccatacg tttcaaccat
    73081 tcttcatcag ataattttgt ttccggcagc cagctgtcca aaaaagaagc ttcgattgcc
    73141 gcttgcggag agtctagaga aagcagatat tggtttctca gcattgcttt tgtctgagac
    73201 agttccaact ctgttatttc accatttcgc aaactttcta attgctcgtg aatcagatga
    73261 agtacttgat ttcggttctt ttcatcgata ccggtttgga cactcatgaa tcctcggaac
    73321 gtatccacgc tactagaggc ataataagct agactttctt tctctctgac attcatgaaa
    73381 agtttagagt gaggaaaacc gccaaataaa ccgttaaaga ccattagcgc aaaacgttct
    73441 ggttcatcgt aatacacatt tgtctgataa gctaggttca gctttgcttg aacgattggc
    73501 tcacgtactt gtcgttcctt cacgatattc acttgaggtt gggtataaaa cagatctgga
    73561 taaactgttt cccgcgactc aaatggtaat tgcccaactg cttcagctgc tttgtccgga
    73621 tcaacatcgc cgacaacaaa aatgtcgatt tgatcatttg ccatcatttc ttgatagtag
    73681 gacgctagcg aactagcagt gatcttgtcc aaatcttcga ctacgcccaa ccctgggatc
    73741 ttttgttccg ggctgttttc aaaataaagt tcttgcaagg cataggaagc aaaagtttgt
    73801 ttatcttcct tcaaactttc caaatataga cgcagattgt tcttttccaa gtcaaacgtc
    73861 aactgatcaa actgatgatt tttaatattt ggataaaata aaacctcttt taaaaaatct
    73921 accgcttgag aaaaaaggtt tggatcattg acatattcac cattcacaaa actgatccct
    73981 gcgtttagcc aatgtaaatt tccttttttt ctaactgata atccaaagct tgcgccataa
    74041 agctctgcaa gttgcgcact taactttgtc tgatccgaat aattcaaact atttgtttcc
    74101 aacatgctgc tgagaagtga acgtttcgtg atgacttctt gttgcagacg cgcagtaaaa
    74161 cggataaaaa tccggatcgt tttgtattgt tttgttggta agacatgaag attcacgcct
    74221 tctgccaatt gatacaccat atttatatgc tccttttcac agttgattgc ccgcttactc
    74281 ttttaatggg tcaacctgcc ttttttactt attcctctgc ttgaaattta taagttcagg
    74341 caattcgccg ttttttctaa atgatgttac actttatagt atagcataga tgttttttat
    74401 caaaagaaac agacggctaa aagcgtatat tgttttttta ttttttattt ttcgatatac
    74461 taaagacaaa taaaagaagg gagggtcatt catgatcaaa gaattcaaag agttcatcat
    74521 gcgtggagat gtcttggatc ttgctgtcgg cgttgttatt ggtagtgcgt ttacaagcat
    74581 cgtaaaccaa gtggtgcaag gcttgatcac accactaata ggttggtttg tcgcaatgat
    74641 cacaggtact tctgatttag aaggagcact ttcaattctt gactggtcgc cgacaaaagg
    74701 cgtcacattt gcgtttggta acgttattag tgctatcatt acatttctga tcactggttt
    74761 tgtcttattc ttagttgtca aagcggcaaa ccgtgcgaag aatttacgct ccaaagaaga
    74821 gcaagtggaa gtggaagaaa ctcctactgc agaagattat cttagtgaca tacgcgatct
    74881 tcttgccaaa caagtggcag aagacaatac acatccagta gagcaaacaa atctttccga
    74941 tacttctaaa taataaagaa tctaaaaaaa agaaagccga ttttcagtgt cggctttctt
    75001 tttttagatt cttaacttgc tacttgttcc tttttcatgt cgatatgtgg aatatcatct
    75061 tccaaataca catctgagat tgccttgaat ccaaacgact cataaaaagc ttgtaggtat
    75121 tcttgtgcgc cgatcacgat tggtttttct ggaaaatttt tctggatcat gttaatcgtt
    75181 tcttgaacaa tctttcttcc taaaccatct ttacggttgt cctgatgaac aaggacacgt
    75241 ccaaaatgga tactctccgc ttcttcatat actcgcgtgt aggcaaggat cttcccatca
    75301 gtatcttgaa aaaacgtatg ccaagcttct ccatcaatgt catcaacttc ttgataagga
    75361 cactgttgtt ccacaacaaa aactgcgatt cgttctttga cgatcgcgta aaactctgct
    75421 gttgacaatt cttcaaattt ctttacctga tattccacta agcaaacgcc ccctgctttt
    75481 ttattcttag cataccgatt cgcacacaaa aaagcaaacg aaccttacga atctcaggct
    75541 cgtttgcttt ttaaactgct tcagttaaaa attcgatctc aactgtccga gtaagtacat
    75601 ctgaatagct gtaagatact cgttcaaaag aattttcttc aggatccaaa tcaacaacga
    75661 atactgaagg ataggtttct gttaaaacgc cgcggcgttc tgtttgacgc tttcttcctg
    75721 tctgagcaac caacatgatt gggctgccga tacgaccttc taaatctttc ttgattgaag
    75781 ctaaagttgt tggcatacag ttcacctcta ctatcaacta taccacatat ttttaaaatt
    75841 ttcaagttta ccataaaaaa aaaagaaatg caataaaaat aaataagaag ctcattaaga
    75901 tttttctaaa ttattcctca ttataaaatt tcaagtgttt ttttattttg agttttactc
    75961 tcccgtaagc gctcattact tgcttgtgat ccattgctaa acattcagcc atgtctacaa
    76021 aatcaacgcc ttgcatataa taatgaaaaa ttttagcttc tatttttgaa aactggattt
    76081 cgcaattttc gattgcttct tttaataaaa gatgctgaat tgctaaaggt tcttgcaatg
    76141 tgatctctgc taaaaagtct ggtccttctg tctctatttt ttggtcgatt gagacttcat
    76201 ctttttgatc acgacgcttc agcgcgttct gcttcctcaa cagagaatag atttgattgc
    76261 ttataacgct tttataataa cttccaaagc taacaccttt gcttttttcg taagttctca
    76321 atgcctgata taaagcgatc cttgcttctt gttcccaatc ctcagaaaca taatttctta
    76381 aataataggt gtttttcaaa cgtagtaaaa gtggaaaata tttttgatac agggcagcaa
    76441 atgcttcttc gtcaccatta cgtgcagcgc gcaataactc ctcagacata aaataattcc
    76501 tccataaatt cgtttatgga ggaatcttat catcaatgat tcatcgaact gattagaacg
    76561 atatgttatt tattttttct cattaaatcg tccaattttt gggacaattt ttttaactgc
    76621 tcttcattcc atggagaatt acgtcggaaa tcaataaaat gcatatcttt attttcttgg
    76681 gctattgttt tttccgtttt ttttatcgtc ttatataatt cataagcaga agttcgtaat
    76741 gctccttggg aaaagatcat ccactgttct gctaaatcgc ttgtcgccac tgtcacttgt
    76801 gtcaaacggt cattcagctg accagcgatt ctctcgatat aactgtcagc cgtttcgtct
    76861 tctttcgtaa aaacaacatc caactggtat ttcttataat tttgttggat gcccggaact
    76921 agttgggcat cgaagacaac gatgacttcc attccttcat atttcgcata atttgataaa
    76981 cgatgtaaaa gagcttctct tgcatccgcc attttgtcct gctttttaag ctggacaagt
    77041 tccggccacg aaccaatcat gttgtagccg tctacaatca acagctgttt tttcatggtc
    77101 tactccccct gacgttggga aaaagcctga tacataagca aaccagcagc aacactggca
    77161 tttaagctct ggacgtgccc ggtcatcggg atcgtcagca attcatccat ttcttttttc
    77221 aatcctggac tcattccttt gccttcatta ccaatgacta aagcaattga tcctttggca
    77281 ttccattttt ggaagtttgt gccggtcata tctgtgccaa atacccaaaa tcctgtttct
    77341 ttgagctgtt gcacagcttg taccaaattc gtcacgcgtg caacagggac atgttcgact
    77401 gccccagtgg aagtctttgt tacgataggt gtgattccaa ctgctcggtg ttttggtatg
    77461 atcacaccat cgacgccact tgcgtctgct gtccgtaaaa tcgacccaaa attgtgtgga
    77521 tcttcgatgc tatccaaaat caaaaagaag gggtcttctt ttttctcttt tgttcgttca
    77581 atcagttggt caagggataa atattcataa ggtgtaatcg caagaacgac tccttgatgc
    77641 acgccgtgat cgctcaaagt ttctaatttt tgtttaggaa cccatttgac tggcacagct
    77701 tgttcacgtg cgatttcttt cagttcttct actttttctc ctcgtgaatc ttcttgaaga
    77761 aagagtttat tccctcgccc ttgttgtagc gcttctactg cggcatggtg cccaaagacg
    77821 aaattatctt ctaatgcttc ttcattttga tcagaaactg actgatttcg tccagtttgc
    77881 tttttatttg aatatctatt ttgttttttg tcttcaaatc cacgtttcga ttgatgtttg
    77941 tttgttcttt ctttacccat ttttttcacc aactttctga atacaccagc ggatcaattc
    78001 ttccatccgc tcggtttgtt ttgtcaaatg cagatagccc atgagcgctt cgaaccctgt
    78061 tgcgacccga tacgtcgtaa catcagcatt ttttgcgctc gtatggcttt tagcatttct
    78121 tcctctgcga taataaagtt cttcttcttc tgtcaaaaga tgttcttcca gcatttgctg
    78181 aatcaaaaag gcttgtgcat tcgcagaaac ataattcgtt gccgcacgat gcagcttatt
    78241 gggttttgtt tctccttgat caatcaggtg gtcacgaaca tagatttcgt aaatcgcatc
    78301 tccaacataa gccaaggcta aaccgttcaa ttgtgtgtaa tctctcatgc ttctcttctc
    78361 catcgggttc cttgcggtgt atcttctaat aagatccctt tttctttcaa caaatcacga
    78421 atttcgtcgc ttcggacaaa atcacgattg cttcttgctt gatttcgttc ttcgatcaat
    78481 tgttcaatct cttcatctaa taactcttct gctgtaaata aaataccgaa gatcgaaagc
    78541 cattgcgaga ataaagcttc tccttgtgcc aagacagcgg cagaaacttt cggctggtct
    78601 agataagtgt tcagccactt agcaagctca tagaccactg tgatcccatt tgctgcatta
    78661 aaatcatcgt ccatttcttc gatgaatcgc tgttctaaat tttctaacaa agcgatttta
    78721 tccgcatcat ctgccaaatt ctctgaggca gtttcttggc ggaatttcaa attgtcaaac
    78781 gtattcttca gtcgttgtaa attggtggct gcttctttca tcgtcgtttc actgtagcgg
    78841 atcggacgac ggtattgtgt ggtcgccatg aagaaacgca agacttgtgg atcaacgttt
    78901 ttgatcattt catgtacagt gatgaaattc cctagagatt tactcatttt ttcatcgtct
    78961 tcgccaatcg ttacatagcc attgtgcatc cagtaattag cgaatttttt ccctgttttc
    79021 gcttcacttt gtgcgatttc attttcatga tgaggaaatt ctaaatcttg cccgccacca
    79081 tggatatcga tcgtttctcc taaatgtttt gttgccataa cggaacattc aatatgccaa
    79141 ccgggacgtc ctttgcccca tggtgaatcc caagaaatct cgccaggttt tgcttgtttc
    79201 cataaagcga aatctaatgg gtcttctttt tgctgctgtt cttcccctgt acgctgactt
    79261 gctccgactt ccagttcatc gatggattgg tcacttaatt tcccataatt ttcaaattta
    79321 cgggtacggt aatacacatc acctgaagat tcataagcat agcctttttc aaccaacact
    79381 tgaataaatg ctaaaatatc tggcatatga tccatgactc ttggatgcag tgtagcaggt
    79441 tcgacattca acgctttcgt atcttcttca aatgctcgga tgaaacgatc agcaacttct
    79501 ggtgctgtaa tacctaattc gtttgctgta cggatgattt tatcgtctac atccgtgaaa
    79561 ttcgatacga aatcgacttt atagcctcga tattcaaaat agcgtcgaat tgtatcgaaa
    79621 gcaatggtgc tacgagcatt tccgatatgg atataattat acacagtcgg tccgcagaca
    79681 tacataccga catgtccctt ttgtataggg atgaattctt ctttttttct ggtcaatgta
    79741 ttgtagattt ttatcattct gatctcctca ctttttctcc tttgattcga acgacttttg
    79801 ctggtactcc taccgctgta gcgtcgtctg gaacatcttt caacacaacg gcacctgcac
    79861 cgattttggc gttttttccg atcgttaccg gtcctaatat ctgcgcattc gcagagagca
    79921 tggctccttg tttaacagtt gggtgtcttt tacccgtttc ttttcctgtg ccgcctaatg
    79981 ttacgccatg gaataaaatc acatcgtcct cgatttctgc ggtttcgcca atgacgattc
    80041 ccattccatg gtcgatgaac acgccagttc caatcgttgc tcctggatgg atctcaacac
    80101 cagttaggaa acgccagaat tgagcattga tcttcgccaa taaaaagagc cggtgctgat
    80161 ataaaaaatg agagaaacga tgccaaaaca aggcatgaaa accagggtat gtcaaaacga
    80221 tctcagctgt cgaacgtgca gccggatcgt ttctctttgc tgcatcaatc gctcgggtaa
    80281 accaactcat gactttccac tcctttcgta agaattttat gtaggaaatc atcttcttat
    80341 aaagaaaaga agcgcctttt aaataagttt ccttatcaaa agacgctttc cgcgtggttc
    80401 cacttttctt cataatcaat gattatctct gacagctaac gcctgttata cgttcttggc
    80461 tactttgttt cctataaaac agtttttcct gttttctgtg tttcgccaag accactccca
    80521 gaggcatttc ggcaaccatt cattgatacc ttgcaccacc cggtatctct cttgtaatga
    80581 tcagctgctt acttttttct gttcatcgtg tttagttcag tacttgattt aaatgtgcta
    80641 atgatttttc acgaccaagc aattcgatcg tttcaggcaa ttctggacca tgcatttgtc
    80701 ctgatacagc tacacggatt ggcatgaaaa gattttttcc ttttacgcca gtttcttttt
    80761 gaacagcttt gatggcagct ttgacagttg gagcatctac tacttccatt tgttctagct
    80821 gtgctttgaa tgcgtggaga acagtaggaa ctgtttcacc agcaagtact tcttttgctg
    80881 cttcattcaa tacaggatgt tcattgaaaa atagcgtaga cagatcaacg atttctgcag
    80941 catagctcat ttgaggttga tacaggctaa cgatcttctt cacccattcg attgtctttt
    81001 catctgggtt ttctgctaca cgtccatcag cgattagata aggcagacac atgtcagtaa
    81061 atgcatctag atccattgct ttgatgtaat ggttgtttac ccattgcagt tttttcgcat
    81121 cgaaagctgc gggtgattta cttaggcgtt ttggatcgaa cattttgatc aattcttggt
    81181 gttcgaagat ttcgtcttcg cccacaggtg accagcccaa taatgcaata aagttgaaca
    81241 ttgcatctgg tagatagcct aattcgcgat attgttcgat aaattgcaag attgattcgt
    81301 cacgtttgct tagtttttta cctgtttcac tgttgatgat caatgtcata tgtccgaagg
    81361 ttggtggtgt ccagccaaat gcttcataga tcatcagttg ttttggtgta ttggcaatat
    81421 ggtcatctcc acgtaaaacg tgagtgattt tcatcaaatg atcatcgacc gcaacagcaa
    81481 aattataagt tggcatacca tcgcgttttt ggatgacaaa gtcgccaccg atattatcgg
    81541 attcgaacga aatagcgcct ttcaccatat ctgtaaatgc gtattctgta ttgcgaggca
    81601 cacggaaacg tacaacagat tctagacctt gtgcttcttt ttctgcttgt tcttcaggtg
    81661 tcaagttcgc acatgttcct gcgtaatgag gcatttctcc tcttgcgcgt tgtgcttccc
    81721 gttctgcttc taattcttct tctgtgcaat agcatttgta tgctcgattg ctagcaagca
    81781 gctgatcaat cagcggttga tagatttctt tacgttcaga ttgacggtaa gggccgtatt
    81841 ctccaggatt ttcaggagat tcatcccaat tcattcccaa ccaagcaagg ttttccaact
    81901 ggcttttttc gccatcttcg atattacgtt tttggtcagt atcctcaata cgaataataa
    81961 agtctccatc attgtggcgg gcaaacaaat aattgaataa tgcagttctt gcatttccaa
    82021 tatgcaggtg cccagttgga cttggtgcat agcgtacgcg tactttcgtc attttcttcc
    82081 tcttctttca aactagactt tgactaacag caaaaattcc gtcagttacg gcttctcaaa
    82141 tatcatttat ttaaagccac tcagcacaaa ttttaccttt tctaaggtaa atagtaaagc
    82201 caactggttg aatttcctta ccagttggct gaatttcttt tttattttga ttgtttagtc
    82261 tttttctctg tctctttttt attgtcgatt cctcgtcctg catgtgcagg tttagcaaag
    82321 atcatgcgtc cagcagctgt ttgaagggca cttgttacaa cgacttcgat acgttcattc
    82381 atgtaatgct gtccatcttc tacgacaacc atcgtgccgt catcaaggta ggctactcct
    82441 tgttggcgtt ctgtcccggc ttttactact agaacattca tcgtttcacc agggatgacg
    82501 actggtttta cggcatttgc caacgcattg atattaagaa caggtacatt ttggaattca
    82561 gagactttat tcaagttata gtcattggtt acaatgacac catctaaaag cttagccaat
    82621 ttgatcaatt tgctgtctac ttcactgata tcttcaaagt ctccatcgta catttcgaca
    82681 gatataccct cttctttttg caaggcattt aggatatcta atccgcgacg accacgcaca
    82741 cgtttcaaac tatcccctga gtccgcgatg tattgtagtt cgtaaagaac aaaattaggg
    82801 atcatcaagg ttccttctaa gaatccagtc tttgtaatat cataaatccg accgtcaatg
    82861 atcacgcttg tatccaagat tttatattta tggaaatttt ctcctgattt tcgttctaac
    82921 agttgactct caacttgact agctgtttct tgctcgattt ttttgcttcg tgaaccaaaa
    82981 actttcttcc attcttcgat tcgtgtcgtt cccattctca atcccagata gcctaagatg
    83041 atcatcagta aaatcggcaa tacactattg acgaatggaa tttccatatt gtaaagaggg
    83101 gtcgagatca caacacctaa agtcaatccg atgatcgcac cgatcgcacc gaagagaaga
    83161 taagtcaagc tgacctcact tagtttttgt tctacttgtt tgataatagc tgagatatgt
    83221 ttggccaaca gcaaagataa taaaaagaaa ataagtgcgc ctaacaggct gttggtaaat
    83281 gtattattca gccatccgtt tgactgttga ccgattgcct gccaagctga gggtaaaaat
    83341 gaaataccca agcttgcgcc gacaatgatc atcagcaaag taatgacacg tttttgcatc
    83401 gtttttcctc cgtttcgaca atcatttatt agttagcgga acacacgctt caacgtttca
    83461 gccaaagttg ctactccaac tatctcgatt ccttttggcg cttcccagtt acctaagttg
    83521 tttttaggta ggtatacttt tgtgaagccg agtttttgga cttctttgac tcgttgttca
    83581 atatgactga cacgtctgat ttctccagtc agtccaattt caccgatgaa acattccgtt
    83641 ggctgtgttc ctttttcttt atagcttgaa gcaatactga cagcgatagc taaatcaatc
    83701 gctggttcat ttaattttac cccacctgca gcttttaagt aagcatcttg attctgaaga
    83761 agcaacccag ctcttttttc cagcactgcc atgatcagag atacccgatt gaaatcaaga
    83821 cctgttgttg ttcgtttggc atttccgaac atagtaggtg tgactaatgc ttggatctct
    83881 accaaaattg gacgtgtccc ttccattgcc acaacgatag cagagccagt tgcaccgtct
    83941 aggcgttctt ctaagaaaat ctgtgaagga ttagcgactt cttccaatcc atgctcatgc
    84001 atttcaaaaa tcccaatctc attcgttgag ccaaatcggt tttttactgc tcgcaaaatc
    84061 cgaaaactat gatgttgttc accttcaaaa tataacaccg tatccaccat atgttctaac
    84121 attcttgggc cggcgatcga gccttctttg gtaacatgac cgacgataaa aatggctatc
    84181 ccatttgttt tagcggtttt gagtagttct gcagtggttt ctcttacttg gctgacactt
    84241 cctgccacac ttgtgatgtc tggctgcgtc atcgtttgga tggaatcaat gataacataa
    84301 tcaggggaga tatgttcgat ggcacgactg atttcgttca tatctgtttc agcgtataga
    84361 taaaattctg tgttgatact tccgaggcgt tccgcgcgta attttatctg ctctgcgctt
    84421 tcttcgccgg atacatataa gacttttccg cctatggctg ctaattgctg agaaacttgt
    84481 aacagcaaag tggatttccc gatacctgga tcgccaccaa tcaagaccat agaccctggc
    84541 accacacctc cgcctaacac acggttcagt tcttctaatt ttgttttgat ccgaggttct
    84601 tttttaggga cgacgtctgc gatttttgtt ggttttgctt tttctcctgt caaacttgtc
    84661 cgagttctgc ggtccgttgt atcttgttcg atttcttcga ccatcgtatt ccattttccg
    84721 caatttgggc agcgtcccaa gaacttaggc gacacatacc cgcaattttg gcaaacaaat
    84781 tgtacttttg atttttttgc cattgtaccg cctcctttta tcctaatcat gagacattaa
    84841 atcaagctta agtatcttta acgttttatt tactggaaga accaaatccg ccttgacgtt
    84901 gagcagtcgt ttgatcttga tctgctttta aaaacggcaa aaagatccct tggccgatac
    84961 gctcgccttt tttgatcact acatccttga aaccaaagtt ggtgaattgg aacatgatat
    85021 ggccttcatt tgcctcatta ttgtaataat cactgtcaat cacacctact ccgtttgtca
    85081 acactaaaaa ccgcttcaac ggattgcttg aacggttagc aagctgcaaa aattcatctt
    85141 ctcccatgta agctttgatt ccagtaggca cgagggttgg tttcaattgt ttttcatttt
    85201 ctgatacatc ttttttcaat ccatctgcga ctgtttccaa cccctttttc cagcctgctt
    85261 tccagatact tggaatcacg acctcttctg ctgcttcaaa atcatagcca gcagcatgat
    85321 gtgtagcgcg ctgcggtaga ttgatatttt gatctttata tttagaaata acttcaaatc
    85381 ctctttttct caccggtttt cct
//
LOCUS       DADVXE010000003        80586 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.003, whole genome shotgun sequence.
ACCESSION   DADVXE010000003 DADVXE010000000
VERSION     DADVXE010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 80586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.003"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(60..1538)
                     /locus_tag="KB913_000174"
     CDS             complement(60..1538)
                     /locus_tag="KB913_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6818569.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(1836..2771)
                     /gene="murB"
                     /locus_tag="KB913_000175"
     CDS             complement(1836..2771)
                     /gene="murB"
                     /locus_tag="KB913_000175"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBB6818570.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2844..3764)
                     /locus_tag="KB913_000176"
     CDS             complement(2844..3764)
                     /locus_tag="KB913_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6818571.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3877..4629
                     /gene="xth"
                     /locus_tag="KB913_000177"
     CDS             3877..4629
                     /gene="xth"
                     /locus_tag="KB913_000177"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBB6818572.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5493..6026
                     /locus_tag="KB913_000178"
     CDS             5493..6026
                     /locus_tag="KB913_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBB6818573.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(6516..7040)
                     /locus_tag="KB913_000179"
     CDS             complement(6516..7040)
                     /locus_tag="KB913_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6818574.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(7033..7506)
                     /gene="tsaE"
                     /locus_tag="KB913_000180"
     CDS             complement(7033..7506)
                     /gene="tsaE"
                     /locus_tag="KB913_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBB6818575.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(7629..8609)
                     /gene="pta"
                     /locus_tag="KB913_000181"
     CDS             complement(7629..8609)
                     /gene="pta"
                     /locus_tag="KB913_000181"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBB6818576.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(8762..9442)
                     /locus_tag="KB913_000182"
     CDS             complement(8762..9442)
                     /locus_tag="KB913_000182"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBB6818577.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            9568..10437
                     /locus_tag="KB913_000183"
     CDS             9568..10437
                     /locus_tag="KB913_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6818578.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            10463..10978
                     /locus_tag="KB913_000184"
     CDS             10463..10978
                     /locus_tag="KB913_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818579.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(11025..11618)
                     /locus_tag="KB913_000185"
     CDS             complement(11025..11618)
                     /locus_tag="KB913_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6818580.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(11643..11822)
                     /locus_tag="KB913_000186"
     CDS             complement(11643..11822)
                     /locus_tag="KB913_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818581.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(11899..12408)
                     /locus_tag="KB913_000187"
     CDS             complement(11899..12408)
                     /locus_tag="KB913_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818582.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(12504..12884)
                     /locus_tag="KB913_000188"
     CDS             complement(12504..12884)
                     /locus_tag="KB913_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6818583.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            13214..13963
                     /locus_tag="KB913_000189"
     CDS             13214..13963
                     /locus_tag="KB913_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBB6818584.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(14147..15424)
                     /locus_tag="KB913_000190"
     CDS             complement(14147..15424)
                     /locus_tag="KB913_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818585.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15503..16147)
                     /gene="pcp"
                     /locus_tag="KB913_000191"
     CDS             complement(15503..16147)
                     /gene="pcp"
                     /locus_tag="KB913_000191"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBB6818586.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16346..17290)
                     /locus_tag="KB913_000192"
     CDS             complement(16346..17290)
                     /locus_tag="KB913_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBB6818587.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17292..17978)
                     /locus_tag="KB913_000193"
     CDS             complement(17292..17978)
                     /locus_tag="KB913_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBB6818588.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            18452..18772
                     /locus_tag="KB913_000194"
     CDS             18452..18772
                     /locus_tag="KB913_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBB6818589.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            18926..19831
                     /locus_tag="KB913_000195"
     CDS             18926..19831
                     /locus_tag="KB913_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6818590.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            19828..20601
                     /locus_tag="KB913_000196"
     CDS             19828..20601
                     /locus_tag="KB913_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBB6818591.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(20782..22206)
                     /locus_tag="KB913_000197"
     CDS             complement(20782..22206)
                     /locus_tag="KB913_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6818592.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            22417..22863
                     /gene="nrdI"
                     /locus_tag="KB913_000198"
     CDS             22417..22863
                     /gene="nrdI"
                     /locus_tag="KB913_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBB6818593.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(22928..24910)
                     /locus_tag="KB913_000199"
     CDS             complement(22928..24910)
                     /locus_tag="KB913_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6818594.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(24924..25820)
                     /gene="murQ"
                     /locus_tag="KB913_000200"
     CDS             complement(24924..25820)
                     /gene="murQ"
                     /locus_tag="KB913_000200"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBB6818595.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(25823..26884)
                     /locus_tag="KB913_000201"
     CDS             complement(25823..26884)
                     /locus_tag="KB913_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6818596.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(27095..27661)
                     /locus_tag="KB913_000202"
     CDS             complement(27095..27661)
                     /locus_tag="KB913_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6818597.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(27689..29191)
                     /gene="eat(A)"
                     /locus_tag="KB913_000203"
     CDS             complement(27689..29191)
                     /gene="eat(A)"
                     /locus_tag="KB913_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBB6818598.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(29449..30570)
                     /locus_tag="KB913_000204"
     CDS             complement(29449..30570)
                     /locus_tag="KB913_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6818599.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            30696..31637
                     /locus_tag="KB913_000205"
     CDS             30696..31637
                     /locus_tag="KB913_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBB6818600.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(31787..32683)
                     /locus_tag="KB913_000206"
     CDS             complement(31787..32683)
                     /locus_tag="KB913_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBB6818601.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            32952..34292
                     /locus_tag="KB913_000207"
     CDS             32952..34292
                     /locus_tag="KB913_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6818602.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            34510..34953
                     /locus_tag="KB913_000208"
     CDS             34510..34953
                     /locus_tag="KB913_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBB6818603.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(35457..36875)
                     /gene="nhaC"
                     /locus_tag="KB913_000209"
     CDS             complement(35457..36875)
                     /gene="nhaC"
                     /locus_tag="KB913_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBB6818604.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(37278..38501)
                     /locus_tag="KB913_000210"
     CDS             complement(37278..38501)
                     /locus_tag="KB913_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBB6818605.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(38532..39371)
                     /locus_tag="KB913_000211"
     CDS             complement(38532..39371)
                     /locus_tag="KB913_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBB6818606.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(39388..40068)
                     /locus_tag="KB913_000212"
     CDS             complement(39388..40068)
                     /locus_tag="KB913_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6818607.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(40070..41143)
                     /locus_tag="KB913_000213"
     CDS             complement(40070..41143)
                     /locus_tag="KB913_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6818608.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(41199..41437)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(41480..41713)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(41790..42461)
                     /locus_tag="KB913_000214"
     CDS             complement(41790..42461)
                     /locus_tag="KB913_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6818609.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(42548..45226)
                     /gene="mgtA"
                     /locus_tag="KB913_000215"
     CDS             complement(42548..45226)
                     /gene="mgtA"
                     /locus_tag="KB913_000215"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBB6818610.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            45885..46322
                     /gene="ndk"
                     /locus_tag="KB913_000216"
     CDS             45885..46322
                     /gene="ndk"
                     /locus_tag="KB913_000216"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBB6818611.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(46344..47210)
                     /locus_tag="KB913_000217"
     CDS             complement(46344..47210)
                     /locus_tag="KB913_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6818612.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(47370..49463)
                     /locus_tag="KB913_000218"
     CDS             complement(47370..49463)
                     /locus_tag="KB913_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6818613.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(50212..50835)
                     /locus_tag="KB913_000219"
     CDS             complement(50212..50835)
                     /locus_tag="KB913_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818614.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(50994..52391)
                     /locus_tag="KB913_000220"
     CDS             complement(50994..52391)
                     /locus_tag="KB913_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6818615.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(52423..53394)
                     /locus_tag="KB913_000221"
     CDS             complement(52423..53394)
                     /locus_tag="KB913_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6818616.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            53768..54193
                     /locus_tag="KB913_000222"
     CDS             53768..54193
                     /locus_tag="KB913_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818617.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(54681..55382)
                     /locus_tag="KB913_000223"
     CDS             complement(54681..55382)
                     /locus_tag="KB913_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6818618.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(55398..55838)
                     /locus_tag="KB913_000224"
     CDS             complement(55398..55838)
                     /locus_tag="KB913_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBB6818619.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(55838..56413)
                     /locus_tag="KB913_000225"
     CDS             complement(55838..56413)
                     /locus_tag="KB913_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBB6818620.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(57261..57740)
                     /locus_tag="KB913_000226"
                     /pseudo
     CDS             complement(57261..57740)
                     /locus_tag="KB913_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(57899..58600)
                     /locus_tag="KB913_000227"
     CDS             complement(57899..58600)
                     /locus_tag="KB913_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6818621.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(58708..60117)
                     /locus_tag="KB913_000228"
     CDS             complement(58708..60117)
                     /locus_tag="KB913_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBB6818622.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(60165..62030)
                     /locus_tag="KB913_000229"
     CDS             complement(60165..62030)
                     /locus_tag="KB913_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6818623.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(62151..63001)
                     /locus_tag="KB913_000230"
                     /pseudo
     CDS             complement(62151..63001)
                     /locus_tag="KB913_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            complement(63311..64024)
                     /locus_tag="KB913_000231"
     CDS             complement(63311..64024)
                     /locus_tag="KB913_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBB6818624.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(64092..64418)
                     /locus_tag="KB913_000232"
     CDS             complement(64092..64418)
                     /locus_tag="KB913_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBB6818625.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(64541..64768)
                     /locus_tag="KB913_000233"
     CDS             complement(64541..64768)
                     /locus_tag="KB913_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBB6818626.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(65090..66343)
                     /locus_tag="KB913_000234"
     CDS             complement(65090..66343)
                     /locus_tag="KB913_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6818627.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            66404..67144
                     /locus_tag="KB913_000235"
     CDS             66404..67144
                     /locus_tag="KB913_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6818628.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(67230..67988)
                     /locus_tag="KB913_000236"
     CDS             complement(67230..67988)
                     /locus_tag="KB913_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6818629.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(67985..69013)
                     /locus_tag="KB913_000237"
                     /pseudo
     CDS             complement(67985..69013)
                     /locus_tag="KB913_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(69033..72200)
                     /locus_tag="KB913_000238"
     CDS             complement(69033..72200)
                     /locus_tag="KB913_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818630.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(72424..73308)
                     /locus_tag="KB913_000239"
     CDS             complement(72424..73308)
                     /locus_tag="KB913_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBB6818631.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(73403..73840)
                     /locus_tag="KB913_000240"
     CDS             complement(73403..73840)
                     /locus_tag="KB913_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818632.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(74057..74968)
                     /locus_tag="KB913_000241"
     CDS             complement(74057..74968)
                     /locus_tag="KB913_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBB6818633.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(75425..75853)
                     /locus_tag="KB913_000242"
     CDS             complement(75425..75853)
                     /locus_tag="KB913_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818634.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(75881..76519)
                     /locus_tag="KB913_000243"
     CDS             complement(75881..76519)
                     /locus_tag="KB913_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6818635.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(76523..78505)
                     /locus_tag="KB913_000244"
     CDS             complement(76523..78505)
                     /locus_tag="KB913_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBB6818636.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            78685..79350
                     /locus_tag="KB913_000245"
     CDS             78685..79350
                     /locus_tag="KB913_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6818637.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
BASE COUNT        23465 a        16654 c        13740 g        26727 t
ORIGIN      
        1 tttgaaaaaa acataaatca gctaataaat atgtgagaca aagctgccat ccataaatac
       61 tagctgattt tttcagttaa atgtctattt ttttctctga tgatggtatt tccaaaatat
      121 tcccagtcat ctggagtcgg tggatttttc caaattatct gttctttatt aaatttttca
      181 agtaaacaat cagataaata aatattcgta cgagaagtga ttcgactctc aatcacaata
      241 ttgtaatttt taaatccttt cacttgagaa ataatgtaat cggtataagc agatccttgc
      301 gaaaaatcaa tacagacatg aatcggtgct tcaaaatatg ataccggaca aataccgacc
      361 aataaaaaga gataatcata aaataagcga atcatgaaac gttcatcttt tcccaagaaa
      421 tagcgtttat tctcttgtat gaccttttgg attgctgtac tgaatattgg atacgtctcg
      481 aagaaaaact gtagctgctt tttagacgta aagctagtca tctcaaagtc gaatatccaa
      541 ttttttcgat tgacatgcat catacccata cgaagttctt ttcgtatata tagtctttct
      601 tcttcagaga tttcaatcga aaatggtaat tgatcaatca attccactga cattttttga
      661 ctaatcatgt ggatatcatg aaaatgagct tccgcaagtc caaatgcgcc atctaattca
      721 aattcttctt ccgtgatcaa aaacaacatg atataagaaa tctcatcaat gatctgctct
      781 ttagggatat gaagaaaaga aatatgtgat aaatccttga tgatcttcat tccttctgag
      841 ctcttaaagt attcatctga aaagaaacgt tttccgattg gttgattccc ataggccctc
      901 aacaaactaa tagtggttag caaattgaat ttgattcgtt ttgttgcaga cagttttaaa
      961 ttgaacagat attcaaaata ttgcacgata ctctttgctt cattcatgac gctttctcta
     1021 aatggcatag aaaaaccatt aaagaccccg aaatataccc caaataatac gttccgtatg
     1081 tttatttctt ccccaactaa tatgtttttc tttaacttta tttgatgctg ttcaagaaaa
     1141 gagactaatt ctcttctttt tacataggct cttgatatgc ttaaaaaatg attctctgca
     1201 aatttttcga tcgttacttt tgaatccacg atctccgtta acagtcgagc aatttttgat
     1261 cgttgaaagt agattcttct taaatttttg atatccgtca aattcagacg ttcgacatgg
     1321 atctctgctt cttctgaaat ttggatctct ggctttgttt tgaattcagt aaattcttta
     1381 tttaattcta tgatataatt tcttgtttta aatttagaca aacctaatgt ttcatataac
     1441 ttaggcagca ctacataatt ctttttctca aattctaaat atctagctag cagcagtttt
     1501 tctctatctt cctcttctat aaggtaatcc aacttcatat cctacacctc aaaaaatgcc
     1561 tcataccaat tacttgatat gcagatgaaa gttcatcttt tcacctatac tgattttatg
     1621 atggattatg cttgtttttt catcagttat tctcattttt tatctttttt ttgagaatat
     1681 tgcaaaaaat ggaaaaattt atgaggaaat attctatatt ttttgtttta ttgtgttaaa
     1741 atgtacaaga tttgcgccat ttgcgtaaac aaccacaaaa aagagcagga cggccaccgt
     1801 cctgctcttt tacttatttt aagttccatt acttattaat tggctaaact tctgcttgtt
     1861 tctgatattg cttgtttttc tccaatgatc cgcacttctg tttctaaaga cacatcaaat
     1921 ttttctttga ttacttcttg gatgtgcgca atcaattcaa tataatctgt cgctgtcgca
     1981 tgatcgatat tgacgatgaa tccagcatgt ttttcagaga cttgtgcacc gccccatttc
     2041 aggccttgca atcctgcttg ttggatcagc tgacctgtat agtgtcctac tgggcgctta
     2101 aagacacttc cgcatgaagg gtattctaat ggctgttttg attgacgcaa ttcggtcaac
     2161 tcatccattc ttgctttgat tgcttcataa tcccctgttt gcaaactgaa tcgagcttcc
     2221 aatacgatag cacgtaattc ttggacttta ctgtgacgat aagaaaatac catttcgtct
     2281 tttgtcaaag ttttcaatgt tccatcttca agcaaaagat ccacttcagc aaaaacatct
     2341 ttgatctctc cgccatacgc acctgcattc atataaaccg ctccaccgac acttcccggg
     2401 atgccgcaag caaattcaaa tccagtcaat gattctgcca aagctgcata agtcgtatca
     2461 atcagtgagg cacctgcttc cgcaatgacc atcgttcctt tgacatgaat ctgtttcatt
     2521 tcagtcagca tgatgactac accgcgaatc ccgccatctt gaacgatcag attgcttgca
     2581 tttcctaata ccatccaagg tatatcatgg attcggcaat aatcgatgat ttgctttact
     2641 tcttcttgtt ttttcgggaa tgcaaggaca tcagctggtc cacctgtttt cgtaaacgta
     2701 tagttcatca atggttcatc aaacaatata gtaatcgtgg ctaagctttc aactatttct
     2761 tctttattca ctgaggattt tcctttcttt tctcaaacgt cctcattatt ctatcacgct
     2821 taatacaatc ttgccagtct tgttcaaagt tgatgacggt agtgatcttt aagcacttcc
     2881 tcacataatt catgacttct tacaacttct ttttgtttaa gcaattctgt ttccgattta
     2941 cctaaacgga tctgagaaaa gaaggcctct accattggct caaacccgcg tttgactagc
     3001 gtgtttgtcc agtcgccaaa ttctttcact ttttttccat cagcatcttg aatgacaagc
     3061 tgggtcagat cgtttacttc ataagtacca tttttacttg ttacttgata tttttctata
     3121 ttagcgccac ttgctaaatc catcgttaaa atagccgttt gattttgtgt ttctaattgt
     3181 aaaatggcat attccaaaaa ttcctttgtt tctcttatct ggtattttgt tctcaaaatg
     3241 ggttcatcta ataaatacac agctgtatca ataagatgta aaaacaaatc ataaaggacg
     3301 aactctgtcg tttcttttgc cgctattcga tttttttgca ggtggatcaa ccgcttatct
     3361 gggatacgtt tcaattcttc taccatagga gcaaagcgcc ggttgaaacc gatcatcaaa
     3421 attatttggt tcttatcagc taattcttgc aattcacgaa cttcatttag atggacactc
     3481 agtggtttgt caatataaac atggatacca ttttctagac attttttggc taattcataa
     3541 tgtacttttg ttgctgcgtg gatcatacat gcttcgattt tttcttctaa aagctcatcg
     3601 atcgtttcat atagatgttg gaacccgtac tctttttgaa ttctttcttt tgtttcttta
     3661 tttcttgttg caaaataaaa atcaagtgtt ccttgttttt tcgcataagt tggtaaatat
     3721 gctttttctg cgatattccc tacaccgatt acaccaatct tcatctactt tcctcctgga
     3781 tcatttagtt actttcatct tacaccattt ttttctaaaa tgaggtacaa tagtatcgca
     3841 aaggtaagga aattaattcg aaggagtgtg cttttattga aatttatctc ttggaacgta
     3901 aacgggcttc gtgccatcgt aaataaaaat tttttagaag tttttcatga gttagacgcc
     3961 gattttttct gtctgcagga aacgaaactc caagcaggac aaattgattt agatcttcca
     4021 ggttattatc aatattggaa ttacgcggaa cgaaaaggct attccggcac agcgattttt
     4081 gctaaaaaac cagcattgaa tgccacttac ggaatgggta tcgatatcca tgatacagaa
     4141 ggccgtctga ttactttgga atattccgat ttctttcttg taacctgtta cacgccaaat
     4201 tctcaaagcg aattaaaacg tttagattac cgattagaat gggaagaagc cttttataat
     4261 tatttggaaa atctaaaaaa acaaaaacca gtcatcgtgt gtggggatct aaatgtcgct
     4321 catcaaaaga ttgatttgaa aaactggaaa acgaatcaaa aaaatgctgg attcactcca
     4381 gaagaaagag cggctctttc tcgactgttg gataacgggt ttatcgatac attccgttat
     4441 ttttatccaa cccaggaagg tgtctactct tggtggaact accgattcaa ttcaaggaaa
     4501 aacaatgctg gttggcggat cgattacttt ttgacgagca aagatttaga gccaggacta
     4561 gctgatgcaa agatccatac ggacattatg ggcagtgatc attgtccagt agaattagat
     4621 ttgaaataaa gaggttgtga aaaagtcgtt tagtttcgag tattaagaaa aattttgtga
     4681 aaatggcttt ccacattttg cataaatttg gcataatacc gagaaactgg cttttgaaca
     4741 ctgtttatcg agagattgtg aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca
     4801 aaaatagttc ctcatatttt tcgtttggtt gggcttatta ccgcagatac aagcttttga
     4861 acaccgttta ttaagaggtt gtgaaaaagc tgcactgcat caagtaataa gaacagccaa
     4921 acaaaaatag ttcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
     4981 tgaacaccgt ttattaagag gttgtgaaaa agctgcactg catcaagtaa taagaacagc
     5041 caaacaaaaa tagttcctca tatttttcgt ttggttggac ttattaccgc agatgcaagc
     5101 ttttgaacac cgtttattga gaagttgtga aatcagcgtc ctgacctgag tattagagaa
     5161 acaaatggca aaatagttcc tcatattttg ctattttttg agctaatacc gagggtcagc
     5221 tgattgaaca ccgtttagtg gagaagttgt gaaaaagtcg cctactttcg agtcgtaaga
     5281 aatttttttg aaaatggttc ctcacaactt tgcataaatt tgacttaata ccgagaagtc
     5341 atgatcccca tctaactcca aatcacaagg aatgagttca aaaactagct tttctcaaca
     5401 aatattacat aaaaaattct atgttttttg ttaaatttat ttgctttttt caaaagtatg
     5461 ttacagtaat ttcccaagga ggttttacag aaatgaattt tgttgccatg gattttgaaa
     5521 ctgccaatca tcagccttat agtgcttgtt ctcttgcgct agtcatggta aaaaatagcc
     5581 agatcgttga tgaattctat acattgatac agcctgagac tccttttttc tggcgaaatg
     5641 tccaaattca cggaatccat caagaagacg tacgcaatgc gccgaaattc ccagaagtct
     5701 ggcaaactat ccaaccatat tttcaaaaaa atcgtttagt cgttgcacat aatgctgctt
     5761 ttgatacaaa ggtcttagcg ggatgcttag attattatca tcttgaacag cctaattatc
     5821 tttctttatg tacagtgaaa agtagccgtc gcctgtttcc tgaatttcca aatcatcgat
     5881 tgaacactgt gtgcgaaaat ttgaacatcc aattagatca tcaccatgat gcattggaag
     5941 atagtcgtgc atgtgcggaa atcctgcttt atcaagaaaa aaaattcggg acagatccat
     6001 tgaaaaaact tgtgactata aagtaaaaga atacttatga aacacacaaa gaggtcgtga
     6061 gcctgccgtt tcactccgag tcacaaggag caatttcaaa aaatagcttc tcatgtttat
     6121 taaatattgt gactggtgac cgaggagctg gcaggagaac accgtttatt ggagaggttg
     6181 tgaaaaagct gttctgcatc aagtaataag aacagccaaa caaaaatagc ttctcatatt
     6241 tttcatttgg ttggacttat taccgcagat gcaagctttt ggacaccgtt taccaagagg
     6301 ttgtgaaatc agcgttttga cctgagtatt agagaaacaa acggcaaaat agttcctcat
     6361 attttgccgt tttttgagct aataccgaag gtcagctgat tgaacaccgt ttattcaaaa
     6421 aaaatggact gcgacacgac ttttgtcaca gtcccttcgt gtgtttttct gccttctcaa
     6481 aaggatgaca gtttctcact cttttcctat ttcttctatt caatcaaata actcatttta
     6541 tatacatcta aaaattcacc tagatctgtt cttgcccctc taggcatgac cgcttcgatt
     6601 tggaagccca tttttcggta aaggtgtacg gctctttcat tacgaacttg aacgtcaagc
     6661 tccaatcgaa aaagtacacc catttccttc gcccaactga tgatttcttc tagcataaga
     6721 gtgcctagtc ccattcccca atattcctgc agaatactga taccgacttc tcccacgtga
     6781 gacaaacgaa attgactgtc tgccttgaca gatgctgttc caataatcgt cccttcatag
     6841 attgcaagca gcaataaatt attattgctt tcgtatatat aatccaactc ttcttctaag
     6901 gtttctggtg gtaacaggag ttctgcttca tccaaaacta aaaattctgt ctccttatta
     6961 acttgtccca tcatcaaaag aatgtctttt gcatctcctg gcactgcttc ccgcaagatg
     7021 atcccaactt cttcactcat gattttcagc ccatttttct agaattcgct gtttgaaggt
     7081 ttcactttgc tccccgtatg agattagttt cacataccgc ttttctaaat ctgtatcact
     7141 tttttctaaa atcagttcca aataatcctc cggcagtgct tcttctaata gatttcccca
     7201 ttcaacaacg gaaagcccat caccttcaaa atattcatct aaccctaaat ctgctccgct
     7261 agctgctacc cgataaatat ccatatgata caacggaatc cgaccttgac tatattctct
     7321 aataatcgtg tatgtcggac ttttgatcat ttgcgttatc cctaatcctt gggcaattcc
     7381 tttcgtcaac gttgttttac ccgcacctag atcaccagtc aatatcagat tgtcacctgg
     7441 cattgcggaa tgaccaattg cctctgcgaa ttgttctgtc attgttaatc ctgatagttc
     7501 gatcattttt catcttctcc cgctcttctt tctttttgcc agtatatcgc gtaatgaagt
     7561 ttttttaaag aaaaaatgaa ctagtcaaga acagcagctg ctgtttttgg ctagttcgcg
     7621 tgtatttgtt aatcaatcaa tgtttgtgct gctgtgataa tcgataattt atatacatct
     7681 tcttcatttg ctccacgaga caaatcagaa accggtttgt tcaagccttg tagaattggt
     7741 ccgattgctt caaagttacc gaaacgctga gcaattttat agccgatatt tcctgactgc
     7801 aattctggaa atacaaagac tgttgcttga ccagctactt ctgaatctgg cgctttcagt
     7861 tgtgcaactg aaggaacata agaagcatca aattgcaatt cgccgtcgat catgtattgt
     7921 ggcgctagtt ttttagcgat tttagttgct tcaactactt tgtctacttc tggcgatttc
     7981 gctgagcctt ttgtcgagaa gctcatcatt gctacttttg gttcgatatc gaacaattct
     8041 gctgtttttg cagaatctac ggcgatttca gccaattctt gcgcagttgg attcacgttg
     8101 atcgcacaat ccgaaaagac atatttttct tgatctcttc cacgtaccat gatcatcgct
     8161 ccgcttgtcc gactgatgcc aggctttgtt ttgatgatct gaagtgctgg gcgaacagtg
     8221 tcgccagtcg aatggatcgc tccagagacc attccgtctg caatccccat atacgtaagc
     8281 atcgtaccaa agtaattcac atcttttaaa atcttttctg cttgttcttt ggatgccttt
     8341 ccatttctac gttcaacaaa agtatccacc atttcatccc acttatcgta attatcaggg
     8401 ctgatgatcg taaagctaga tgttttgatt cctctggcat gcgctgcatt tcttatttct
     8461 tcttcgttcc ctactaaaat gggttccaca agttcttctg ctttcaaccg ggcagctgcg
     8521 cctaaaatac gagcatcagt agcttccggg aaaacgattt tgatcccacg gcgaacaatt
     8581 ttaaatctta aactatcaaa caattccaca agatgacctc cagacgtttt tatatgtatt
     8641 atcatacact attccagaaa aaaataacag tttattttat ctgtatcagt caaaaatgct
     8701 ggaaaaatta agtttttcac atacaaagcg aactgcacta taacaggaaa gcgctgtttt
     8761 attacactgt ttcaggcagt tgccaatcaa tcggttcttc tcctaacgca aggagcgcat
     8821 cattcgtttt cgagaagggt ttggaaccaa aaaagccacg acttgcagat aacggactgg
     8881 gatgtggaga tgttatgatg atatggcgac tcttatcgat cattttgatt ttttcttgtg
     8941 ccggttttcc ccacaagata aacacgattg gtttttcccg ttcatttaat ttttcaatga
     9001 tcgtgtctgt taatctttcc caacctttcc cgcgatgaga atacgcttgc ccttcccgaa
     9061 cggtaagaac ggtgttgagt aaaaggactc cctgtttagc ccatgacact agatttccat
     9121 gttgaacagg tgcgattcca agatcatcat aaagctcttt atagatattt cttaacgatg
     9181 gcgggatctt tacgccaggt tgcacagaaa aagataagcc atgagcttga ttttctccat
     9241 gataaggatc ttgtcctaaa atcaccactt taacttcttc ataaggagtc aattccaatg
     9301 cttcatagat atgatacata tctggatgga tcttttggga cgcatattct ttttttaaaa
     9361 attctcttag atgcagataa taatcttttg aaaattctga ggacaaaact tcttgccaac
     9421 tgttatgaat gatttctttc aaaaactcca cctcctaata aaaagaataa ctcacatttt
     9481 cttcaatcac aagggacaat cttcaccctc agcacttgat taatatggta aactaggaac
     9541 aagaagcaga aaggaacgat aatcattatg atcaaattaa ttgcatcaga tatggacggc
     9601 acattattag atgcccatat gagtgtttct cctgaaaatg ccgaggcgat acgttttgca
     9661 aatgatgccg gtgttgagtt catggtcgct actggtcgaa actatcaaga agctcgcgca
     9721 gctttagatg aggtaggaat cgattgtgcg atgatcactt tgaacggggc acaggtattt
     9781 gataaagaag gaaattcatt gtttaccgtg tcgattccaa ataatcaagc aatctctgtt
     9841 ttagatattc tagatgctaa cggtatttac tatgaagtag caaccaacga tggtctttat
     9901 tctgaaaatc aagcgaaacg aattgaaagt tttgcttcca tggtggctac ccatttacct
     9961 caccttacgt ataaaatggc gattgccatg gcctcagcta agctggagtt attgcacatc
    10021 acatacgtgg acagtattcg tgctattttg gaagaaaaga atctggaagt tttaaaaatt
    10081 atttgttttc atacagaagg gccagctgta ttaggtccag ttggaaagca gatttctctt
    10141 ttaggcgatc tagccgttac ttcctctggt caaaacaata tcgaagtgaa ccataaaaac
    10201 gctcaaaaag gaattgctgt tgcccatgtc gctcacgagc gtgggatttc tttagaagaa
    10261 gtcatgacga ttggcgataa cttcaatgat gtcagcatgc tgcaagtagc aggagtcagt
    10321 ttcgcaatgg gaaatgcaga aatcgaagta aaagattatg ccaaatatac aacggacaca
    10381 aaccttgaat ctggcgtagg aaaagccata ttgcgcgcga ttgcagaaga cttgtagttt
    10441 tatctagaaa agagggatat agatgtcaga atttttcatt caggaaaagc agcttggacg
    10501 tgcaactcgg acaattgtca aaaacgaaaa aggacattcc ctgtttttga tggttggtcg
    10561 ctggggaaca aagggcgatg cattgtctct ttatgccatg aatggcgatc tcgttgctca
    10621 catcaagcag ataagcctga cattcggtac gcgttttgag ctgtataaag agttcgaaaa
    10681 ggtgggaacc atgcagaaaa tattcaattg gcccggtgac ttttattata ttcgtagact
    10741 tcactggaca gtccaaggtg atatctataa tcatcaatat caaatccatc atttcaatca
    10801 gcaaatcatg aaaatggata aagcaacact tttttcagga gattactatg tattggatgt
    10861 ctcaaatgat gaagatgctc cagtttgtat ttgtattgct gcggttttag attactggct
    10921 ctaccgtaaa gacaaaagtc gcgataagcc tgtttcttac cgacttaact taagttaaaa
    10981 agatgtacct gaaatgcgga aatacgcatt tcaggtacat ctttttagat attcttttgc
    11041 atatgatcat aaagatgacc actgatcatc cgctgaccga caactttgaa gtcatggcgt
    11101 tcgtataatt ttttagcctt tggatttttt tcatccacac ttagaccgat gacggagcga
    11161 ttagctttct tcgccaattt aggtaatgct tctaataatc gcgaaccgat gccttgtcct
    11221 ctaaaatctt ctgatacact gatagagtcc aaataccatt cgttgggaaa cgtttcttta
    11281 tcaatgaaca aacgtgtaga cgcatctagc tgatatttct ctaagatagg taccagtggc
    11341 tgatcgatga ttgattcttc ttcatctgta taaccgtaag caactcctgc aactttaccg
    11401 tctatttctt ctacgatacc tcgtgaataa ctgtaacgat aatttggatc agtgattgct
    11461 tcttctaaaa tctctaaagt cttttgttcc cctgtctgct tcaaaaatgg cagttccata
    11521 tcttttagaa tcactaagat caatggggcg atttctggag catcttcttt tctcgcaaaa
    11581 cgaatcatag tttcctctcc ttttctccat tctaacatgc agaaaaagaa atcgcaaaat
    11641 cgttatttta aaaaatcttc aatcttttca gtaatgaaat aaccatgagt aacgattctt
    11701 gccgcttcag ttcggcaata agggcagacg actggcattt ctttatcatt atgttcgact
    11761 acattattga cttcttcgta tgcaaatttt tttccgcaat tagggcattt cattttttcc
    11821 atgttatctc aacttccttt catctttact ctcttagctt actcttatat tgtaaaaaag
    11881 agaagcaata tccttcttct atgcagatat ccatacctga cggtcctgtt ctccatctat
    11941 taatcggact ttataataag gacgttcatc tttgactaga agtgtccact ctttcacttt
    12001 tgcttttttc ccgtagtagc tgactgcttc cttcatcgct gcttgcggtt gtttgaactc
    12061 ttccgttttt tctatatcaa aaagatgttc tgcggccttt tccgtgtcat ttcgtacggt
    12121 tgttttccca gtggatggat tgactgctat gacttgtcct tcacaaaaaa actggtattc
    12181 atatgttgca ttcgtaggat tctccaaatc tttttcaact gcaaaatgaa tagcagatat
    12241 gttatgttct tttgtttcgt tttttacgat tgctgctgct tttttcaatg agatccgata
    12301 ttcctggtca ctaatatcat ccatgtgaaa agcggcattg agcagtcccg tcataccggt
    12361 aatccctatt acgatgaggg cagcaacacc aaacatcatt tttttcattc ttcattctcc
    12421 tgtttctttt ttttaaagaa tatcaagaaa tgaacgaatg aaaaatcgaa tgaaacgaaa
    12481 aaaaagtgac aattttgtta tctttattcg tgcagttcta atggcaatcc gtctggatca
    12541 aagaaaaacg tcattttttt tcctgtaaag gtatcttctc taatcggttc tgattcgatc
    12601 cctaaggact gcaattctgc aattgtttct tcaatatcgt ctactttgaa agcaagatga
    12661 cgcaagccac aagcttctgg atagtttggt cgttgtggcg cattagcaat tccaaaaatc
    12721 tccaattcag cacttcctag tttcagatct aatttatagt catctcgttc tttgcggtaa
    12781 ttttctctga ttacttcaaa tcctaattta ttaacataaa aatcacgtga tttctgataa
    12841 tctgaaacaa tgatggctat atgatggatc gttgtaaggt tcatatgagc actcctattc
    12901 ttcgtttaag ctcggatcta tattaatctc cagttccatt gtaaatgtgt cagattgaaa
    12961 aaaatagctg tttttccttt ttataagaaa aaaggcaaaa aaaacagaaa gtaggtcctc
    13021 caagacactc ttcctgttcc caatataata aatgaaagta agaaattata ttttcaagaa
    13081 aacaaacaga aaattatcat aacacaaatt atttataatt gaaagactag ttttttttca
    13141 agaaaagcat acaatagatt gtgttagtaa atacagaaca cactacattt agtgtcttaa
    13201 ggagtcctca tacatgaagt catattttca gtttttagct catcagctaa aaggctggcc
    13261 gcaacaaaat tattatcttt tctttttcag tcttggctgc caggtcatga ctcttgtcaa
    13321 tagtcccatc acttggctgt ccgttattac atttatcggt accacgcttg gtgtattgtg
    13381 tattttatcc atcaatgcgg caaaatcagt caacggtatt ttaggtattt tgtctgcgat
    13441 ttgttttatt atcgttgggt tttcagcaaa gaactattta agtatcggtg aacagattgc
    13501 ttatatgatc acattggata tccccgtatt gttaagtaaa gaatggaatc ataatatggc
    13561 ttcaaaaatc cgaaaattca ctggaaaaag ctggtttatc gcaatcatca gtactttcct
    13621 tgtctatctt gtttcaggat tcctgattgg tcgttataca gatgatcctc ggccgtgggt
    13681 agatgccatt gctttttcta ttagcttgac tgctggtatc atcagtttct tgcgttacaa
    13741 caaccaatat tactggtggt tagcttcagg gcttgctcaa atggtccttt ggtatatttc
    13801 atttacgcat ggatctgcaa gtttggcgat gttcgtgaac agctctgttt acttgctgaa
    13861 tgatgtcctt gcatttaccg tttcaccttg gtataaccaa aaagaacgtg aacgtatgca
    13921 aaaaatggaa gaagaatact acaacgcaca acaacacgca taaaaaaact gagcgtggga
    13981 caaaagtaaa gaacactttt gtctcacgct ctaaacacgt ataaacggcg gaatcagaag
    14041 caactccttc ggaaataagc tgaaattcac aaaaatttga aaagcaattt tcgtgaattt
    14101 cttcttattt cttggagtta aacgcttctg tcccagcctc tattttttat agtaattcct
    14161 tcagatactt tcttgcctca tcattgaaac gcagtgattc ttctaacttc tgataatatt
    14221 ccaacgcttg tttctgagct tcagtaaaac gataatgttt tcctttccat ttgtcgattg
    14281 tctcttgcac atttccagat tggatatctt tcactactag ttgccatttt tcttttgaga
    14341 ctgtacggtc tttcttatca gcagattgta tagcttctcg ttctttacgc aatactttta
    14401 aaaaaccatt tctgactatc cgaggaatgc tgtcgaagaa cccttctgta aaaccatagc
    14461 gacaatattg cttccaaata aatagataga tttttggttg gatgaatcgt tggtttttcg
    14521 caaaatattc catctgagca gtgacttctg gtgttcgttg acgttttgtc tttctcaaca
    14581 cggaaataaa tgtttcaaaa taagcattag gatgtactgg cacttcttca tatacgatgg
    14641 attgccaatc tttacgtaaa aatgcgcgat agttgatcaa gaattcttct acatccttta
    14701 ctaattcttc tgcaaagtcg tcaaatagtt ctttttttat ctgtcgcttt tttgactgcc
    14761 cattgatgtg ttcacttatt ttcttgattt cattttccaa tgcttgataa tccgctatgt
    14821 aaatcggcat ttctacttgg cgaaattctg cgagccgctg agctaatttt atatccggta
    14881 aatatggctg tttcatccga cgattttggt acaagacaaa acagtatttt tgccatagtc
    14941 cttcaggaaa atcgatattc ttctgcttaa gccataataa ttcgtctaag gccagatcaa
    15001 cttttgtcat tccctgatgg atcgaagctg ccactgtcgg agagacatgc aggtgatcgg
    15061 caaagtggtt gatgcctagt tttaggatct ttccggtttt tggcgattta acgatgtatt
    15121 gcacttttaa ttctctacca cactcacaat acaatttttg ctggcttcgt tttgttcgaa
    15181 aaaacggatt gatcttgaag tcagaaaaca cccaatctgt tgcagctaaa taatgttctt
    15241 ccataaaacg agagctgatt agatatcggc ggtgcttatc gactagttcc cgctgttttt
    15301 tcgttaattt tgcatagatc tcccaacgtt gactgcttgt gtattgttta gaaattttga
    15361 tgggatagct tttgctgatt tcttttggaa accattcttc aaagacggat tgccattctt
    15421 ccacggctgt ttctttcctt tctaattaca aaaagctggc tactaacata acgttagcaa
    15481 ccagccagtg tttcttgcta aattagtgag ttgttccggc atttccggaa atatcttctt
    15541 tattttctac tgctgcttca actgcataag tcaaagaaga agcaatgtct tctaaagaca
    15601 tagaaggcgt acccactgga cgatcgatca cttgatcggg tgagaatggc acgtggatga
    15661 acccacctcg aattgccggg aattgtgttt cgatcaaatg aagcaaacga tacatgatat
    15721 cattgcagac aaatgttcct gctgtataag agatgtacgc tggtagacca tgatcttgta
    15781 cattttttgt cattgctttg attggcaatg aggtaaagta agcggctgga ccgttttctt
    15841 ctaaagccgt atcgaatggc tgatttcctt cattatcagg gattcttgct tctgctagat
    15901 tgattgcgac acgttcgaac gagactgctg accgcccacc tgcttgtccg acacagatca
    15961 cgacatctgg ttggtgctgt tggatggctt ctttgactac ttgactgctt ttttcgaata
    16021 cggtcggtac ttccactttg atgatttcag caccgctgat ttcatctggc atttttttta
    16081 ctgcttcata ggctggattc actttgtccc caccaaatgg atcaaaacct gttactagta
    16141 ctttcatctg ttgttcctcc gtccgattga tttaacatat ggttatcttt tatcatacca
    16201 ttttccttga acagcgtaaa taaaggaaac aatagtttaa ataacataac agatcaaact
    16261 taatatattc ttataaaaaa atagtgttcc actacaatgt tagaagaggt tgcgacaatt
    16321 attctgtcac aacccctctc ttctattatt taaatagaat catataagca atttggaaaa
    16381 ctagcataaa taacgcaata aacaactggt ttttgatcac tccgtatttg tctttcatct
    16441 ccagcatcgc tacaggcacg atattgaagt tagcagccat cggtgtcagc agggtcccac
    16501 aaaaaccgca agtcaatgca accattccta ttaacgctgg attcgctcca tgactaaata
    16561 cgaatggtgc accgatccca accgtcatca cggtgatggc cgcaaatgca ttccccatga
    16621 ttaccgtaaa tatcaccatg ccaagagcgt aaatgatgat gccgatgttc acatttcctt
    16681 ctggaacgat cgtacctact gcattggaaa tcactgtccc aactccagcg cttgtaaata
    16741 ccgcacctag agaagctaaa agcattggca acatgcttaa cggccctact gtgcccagca
    16801 tatctgctgc atcatctaaa aatgtacttg gtcgattatc tcgagaaaag aacatcaaga
    16861 ttagcatggc tgcaaaaaca ccgacgccca cgccgactaa agcacctaaa ttggtaaata
    16921 gagcaaacaa gatcgcaaag acaccgatac tcaaagctgg aataaaaatt ttcattccta
    16981 gtttgtctga cattttttcc atatattctt ttgatggaag ccggctttct cctttgctga
    17041 ctttcttagc aattgctggt atggtcatcg caaagatcaa gccaccgttc acgattgccg
    17101 gaagccatct tcctcctgca ataactaccc ctaagaccgt ccagaaaaag gctgacccat
    17161 aacgatgagg attggtttta tctgttaaat ttcttactcc agtgtaaatc aatacgagtc
    17221 ccatcacgat ataaaggatc tccagtaatt tatcgcctaa taaaatatca ggatttgtaa
    17281 aaaagtccat cttattgccc ctttcctgga taatatttct tcgctaattt cttttcttta
    17341 agatagaagt agacacttgc cacaactaaa gccgtgatag ccactggaac ttccactaaa
    17401 gcaagctgtc ccaatgttac gtcatatcct agatctttca gtgttgattg gactagcaac
    17461 gcccctgctc ctccgatgaa tagtacttgg ccaaagaacc agcagacatt ttccatagct
    17521 gaagccatac cttttagttc ttcttcatgc ttaggatgga cttctaaccc ttttgattcg
    17581 atggtcccca atgccatcgg taaaatgatt ggacgaacaa atccagcaac tccaccaaaa
    17641 ctcacgttaa aagccgcaaa gatcattcga aagatcccat aaatatctac aatcatacca
    17701 gcagatactt tcttgaatcg cttgatcaag gaagccgctg attctttcag accatttctt
    17761 tcaagcgttc ctgttgccaa cataatgatg ataaaaatcg ccatcccgcg attgtttaca
    17821 aaacttgtac ctaaaagttc taacattcct tgaatgccaa gaccgccagt caaagctgta
    17881 acaactaaag caaccattac gatcaatatc gagtctaatt taaatgcaaa cccgagaata
    17941 acaatcaaga cgcctaaaag gctaagataa ttttccatat attttcctcc ataaaatgac
    18001 aatatttttt taattataaa gcaaaacaca taaaaaatat agttgttttc tcacgaaata
    18061 gacactattt ttaaatattt ttcgttattt ttttatcaca aaaattatct tacttattgt
    18121 aaggtaaagc tttttttaat ttattgcccg ataatatata gaaataaggt ctagttactg
    18181 ttttttttaa atgattaata aataacaact tctttctatg aaattgcaaa gcattcatct
    18241 tcttttccgc taacgatata tccgtcagtg cttggtacac tttactaaaa agtatgagat
    18301 tgccgatatc tggataggtg tgctatacta cagaaaaaga tatacaatct gccaccgggt
    18361 aggataaaga ggatgatcat tccattaggt ctttgaaggg atgattttcc tctttttgtg
    18421 tattttttta tagttaagga ggaatgtaag tatggcatgg atggaattaa tcatagcagg
    18481 aattttggaa gtattctggt caacgatgat gaaatggagt gatggttttt ctaaaatcaa
    18541 ttattctttt tacacagtga ttggcatgat tgctagtttt tactttttgt caaaggcaat
    18601 caaaagtttg ccgatgagtc tctcttatcc tatctggaca gggattggcg cagttggttc
    18661 ggtcataatt ggtgtggtct tgtttcatga taagctgaat ctttccactt ggttctttgt
    18721 ggggatgcta ctcatcagta tcattggcat caagattact agcggccact agacacttgg
    18781 aataagtact gatcagaaaa aataagcctt tttatttaat attcaatttt tttatgaaaa
    18841 aataagaaat aagtccaatg acctagcgac ttctccactc atcaggtgta tgcttgtact
    18901 atctatagaa aaggagtgaa tatttttgaa aagtctttcg gtccaagaat tatccaagaa
    18961 ctttggtcac aaacaagccc tcagcgatgt cagttttagc ttatcccctg gcaaaatcgt
    19021 tggattagta ggtcctaatg gcgctggaaa aacaacgatc atgaaagcta ttttaggact
    19081 gatccattac tcagatggaa caatctgtat tggtgaaaat gagatttctc cctctagtca
    19141 taaagggttg gaacaagtag gagcattgat cgaatacccg ggtatctatc cattcttaac
    19201 aggctatgat catctgaagt tattctctga aaccaacgat gtatctgcta tcgacactat
    19261 cgtgaatcag ctcaagatgg aaaagtacat tcacaaaaaa gcgaaatcct actcgttggg
    19321 aatgaaacaa aaattgggaa ttgctcttgc cttactgaac catccgtcta tcgttatttt
    19381 agatgagccg atgaacggtt tggatccaca agcaacaaga gatgtgcgaa aaatcattac
    19441 cgacttggct actcagggca cctctttctt gatctccagt cacttactca gcgagcttga
    19501 aaaaatggtc gatgagctga tcctgatcaa tcaaggaaag atcatcaaac aatgtacaat
    19561 ggctgaattg aaccaaacag cgcaagattt catcgttatc tctacaacaa atgatctagc
    19621 tgctcgaacg atcttgacag aagctggata tactttggaa gatcctgata aaatcaagct
    19681 tttaaaagaa aacgaagaat tattaggaac cgtgatccag ctattgtctg cacaaaatat
    19741 ccatgtgaca gacgtccagc atctgacgaa tgatttggaa tcttctctat tggaaattct
    19801 ggattcagta aagggggaag aagaaaaatg acattgcttg taaaacaaga attatttaaa
    19861 ttgatcaaga aaaagtcaac tgctgtttta tctgttctat tagttgtttt gctcatagga
    19921 acagcacttc tagccaaaaa atacacgacg atcattgatc cagttgaaat gactgctcag
    19981 ctttttagtg ccacatcttg gattgtcttt atcatgattg cagctgcaag cacgatcatt
    20041 tcgatggaag cacaatatgg tacattgaaa aatctccttt atcgaaagta ttctcgagga
    20101 gaaatattag taagcaaatg gatcacatta gttatttatt ctgtttattt atacctttta
    20161 gctattattg tcactgtgtt gatgaaactg attcttttcc cttcgatttc cttcacggag
    20221 aaggtttcta ctggtcaaac actgatccaa agcttgttca cttatacttt gggtagttat
    20281 atcggtttat ggctgatttt aagtttagtg ttgatgattg cttgctttat caatagttcc
    20341 ggcgcatcca tctcagcagg aatcgtcttt tattttgctt cgtcaatcat atctggtatc
    20401 cttattgcac tcatccaaaa atgggagtgg atcaaatgga atccgatcag tatgttgaat
    20461 ctgcaaaacc aaattggaaa cgaagagatc atgaagcaat tgactcatct ttctactaat
    20521 caaatgctat tcggtaattt agcttacatc gttttgttct tagcattagg atatctcgta
    20581 tttaagcgaa aaaatgtatg atgactcatc aaaaaagagg ctgtgaaaga gacgttcagc
    20641 cttattgccg attggctgtc tcttaaacac cgtttattct gaaaaaggag ctgtgacaac
    20701 atttgtgtca cagctccttt cctagtatgt ttttgaataa acgacaggct cacaacctct
    20761 ctttatactt cttttatact tctatacgtg aagcatccca gtggcaaata aaaccattgc
    20821 aatcactccg accatcgtca cacctataag taaaatctta tctaagtgga tatgttgtac
    20881 aggctcgttt tgctccttac gtgctttgag gtaaaaataa atgcctggca agaaaagaac
    20941 aagaacaagc attacttcat taaaggctac gactagcata gcccatactt gaaaggcact
    21001 tgctaaaagc cctactaaaa attggaccca ttctttccgc tgataagaaa gtttcatttg
    21061 gtacaatcct aagaaaagcc acgtgaagaa aatagctgct gtaccaagtg tgtaagcaaa
    21121 gttataagca ctgtcagtga ataataatga aagtaaaaag acattcgtac ataacgtcgt
    21181 caatacgata gcataagttg gtgccccatt tttgttgagt tttccccatg ctttaggcaa
    21241 aagtccgtct tcagccatgt ttcccattgt ttcaatcggt aagatcgtcc atgagagcca
    21301 aacaccaact aaagaaatga tcaaaccgcc gttgatcacg actgctcccc atttaccaac
    21361 catcatttca aacacatagc ccatagcagg ctgcgccttg atcgtttgca gctgattcat
    21421 cgtcattgtc ccatatggaa gcatggaaac caagacgtaa ataataatca agccgaatat
    21481 ccctagaatc gttgctttcc caacatctga ttgttttttt gctcgtgaac ctacgacaga
    21541 ggctccttca ataccaacaa atacccaaag catcaccatg atgcaactca atacttgact
    21601 ggaaaacggg atcggctgtc cattcgcatt caatataatg tcgctagaaa agttatcaat
    21661 gaattgttgg atcgaaaacg tgctgatagc tactacaata aataaaaata atggcactaa
    21721 tttacagaat gtgacgatag cattgacgaa actagcattt tcgactcccc gattcactag
    21781 ccatgcatat ccccataaaa agactgtact catcacgatc gatgccagat tttgcccacc
    21841 ttcaaatact gggaagaaat atcctaatgc gctcatcaac aatgttgcaa aagctacgtt
    21901 gcctaaccag catgtgagcc agtaacccca accgctgata aaaccagcga aacggccaaa
    21961 accttcttct gcgtaactaa agatcccgcc ttttaaatct ggacgttttt tattgatatt
    22021 attgatcgac aaggagagca tcaacattgc tgttcctacg agtacccaac tgaaaatagc
    22081 tgggccgcca gccgatccgg agatgtccgt cataatacca aatacgccac ctccaatcgc
    22141 tgaaccaatt actaaggcag caagtggaat taaaccaatt ccttttttct gttgctctgt
    22201 atccatgtaa gcatcctcca aaataaaacc gcttttatca aaaagtataa caaacctttt
    22261 ttatttttac ttaattaata aaaactttaa tagaaatata attctaccgg cttttttctc
    22321 attatacaag caaagcgcct agtccctttc caaattacac caccaaaaaa cttaaaaaag
    22381 atgctatact aaaaggaaag aattggagga tgatccatga acattttata tatatcgatt
    22441 tcaggaaata cgcgtgcctt tgccaaacat ctagcagaat atgctgaaaa aatgcatgca
    22501 gaagatcctg tcaatcctga agttacttta aaagaaatcc atgaaaatag tgattttacg
    22561 aaagaaacag aaccattttt tactttcgtt cctacttatt tagacggcgg aaatggttta
    22621 gataacggtg atacagaaat cttgaccgaa acgatgcgtg aatatctgga acatgaagac
    22681 aatcataaac tttgtcttgg tgtagtcggt agcggaaata aaaacttcaa taatcagtat
    22741 tgtctaacag ccaaacaata tgcacaaaca tttggctttc ctttcttggc agattatgaa
    22801 ttacggggaa caccatctga tgtgacacga atttatcaga ttttagcaga aaacaataaa
    22861 taataaaaaa gaagaagctg aaaaatagat ttcagtttct tctttcgttt ctattgtttc
    22921 tatcatatta agctttgaca tccatcacag gtgcttttgc ttttgcttta cctgtttttt
    22981 ccaagacaaa gttttttaca cgatccatat tggttaccaa gacgatcatg gatgtttctt
    23041 tgcctgctgc tttgatcgct tctaagtcag cttctgctac aagcgtatca ggtgtcactt
    23101 gctgcccttc tgttactttc acatcaaatg gcgtaccgcc taagtcaact gtgttgattc
    23161 ccatatgaag caagatttct aaaccatttg gcgttgtgat cccaatagcg tgtttcgttg
    23221 ggaagacaga gctgactacc ccagtaactg gagaatagat atgtccgttt tctggttcta
    23281 caaagtagcc ttcacccatc atcttttgtg caaaaactgg atcacttgct ttatctaaag
    23341 aaacaactgt tccgtcagca actgatgaga ggatagtcac actttcagct gaagtttgag
    23401 gtactacttt ttcaggcact tcatttactg tggctgtttc agtcgctaat tcttcttttt
    23461 ctaaacggtc tttaggaata ccgaagaaga atgtagcaac gaagccacca gcataagctg
    23521 ccaataatcc aaggatgtag cctaaccatt taccgtcaga gatcaatggg atcaaagcgg
    23581 ctcctgaagg tccaatagcg atagccccga catttccgat cattccgatc actgccccgc
    23641 cgatacctcc accgatacaa gcagtaataa atgggcgtcc tagaggtaat gttactccgt
    23701 aaatcaatgg ttcgccgatt cctaggatcc cgactggtaa agctcctttg atcatttctg
    23761 ttaattcttt atcttttttg cagcgaatcc ataatgccaa tgctgcaccc acttgtcctg
    23821 caccagccat cgcaagaatt ggaagcaata gcgtacgacc agtttcatca atcatttgca
    23881 catggattgg agtcaaaatt tgatgcagtc cgaacataac catcggcaag aataatgtgc
    23941 ctagaacgaa gccggcaaat gctccaccaa cgccaagtac ccagttgatc ccaccgacca
    24001 tgccatcaga aatgaaacct gctaaaggca tgatgaagaa aatttcaatc agaccgatgg
    24061 caatcaatga aagagttggt gtaacgatga tatctaccgc atcaggtact actttatgca
    24121 gttttttctc aacgattgac aatagccaaa cagcgaagat gacacctagg atcccacctt
    24181 gtccagctgc aagagcttca ccagtaaata agtttttcag tggtgcttcc ggattcatcc
    24241 ctgtcagcat cacaacggcc ccgataactc caccaagagt tggtgttgca ccaaaaactt
    24301 gtgcagcatt gatacctgta tagataacta ggtagctaaa catcccgttt ttcaagatgt
    24361 tcatcacatc gatatattgt tgccatgttg ctgcatcaag tgttccggct gtgactaagt
    24421 ttgctaaaac tgcggcaatc cctgccacga tcccagtacc gacaaatgca ggaatcattg
    24481 gcacaaagat attagaaatg tcttttaata ccgatttgat tttagatggt ttttgtttcg
    24541 atttttgtgc cgctttcatt tcttgtgccc gttcgtttac acggtctttt ccagatgctg
    24601 atgaatttgc tgtagctgta cttacagaag aaagtttttc tcctaatttc acgcctgcca
    24661 aatcaaccat ttgctgtgct actttgttca ctttcccagg tccgatgatg acttgaagct
    24721 gttcatcttc tactacacca agcactcctg gaatcgcttt taattcagag acatttacaa
    24781 gatcatcatt gatgatcttc atacgcacac gagtcatgca gtggacaatg ctttctacat
    24841 tgcccatgcc gcctgcccct ttataaattt gttttgccag ttcttccaaa gtcagttcgt
    24901 tttttgccat ggtcttttcc ccctcataag gtccctttta caaatccgtt tgcttcagct
    24961 aattttgctt gagcttcctc tttatcacta tttgtcaaaa tcatgacgat agccagctta
    25021 acattttgat ctgcttcttc aaagtacttt tcagctgttt cgtaatcagc ttctgtcgct
    25081 tgcatgatga ttcgttttga gcgttcgatt agtttttcat ttgttggttt gacatcgacc
    25141 atcaagttat tgaatacttt acctatacca atcatactga tagtagaaat catattcaag
    25201 ataagttttt gtgctgttcc tgacttcaat cgagtagagc ctgtcaaaaa ttctggacct
    25261 gcatcgactt cgattgggaa atccgcgtgt ttactgattt cggcttgttt attgcaagaa
    25321 atcgttcctg tgacagcacc gatcgatttt gcgtaatcta atccaccgat cacatatggt
    25381 gtacgaccgc tagctgcgat accaataact atatcatttt ttgtcaaatt cagcttgatt
    25441 agatcttctt gccctagctc ataagaatct tcggcccctt cgacagctac agtcattgct
    25501 tcttctccac cagcaattag acctatgacc atttccggtt ctacaccgaa tgtcggtacg
    25561 cattcagcag catctaacac acctagtctt ccacttgttc cggctcccat ataaatcaga
    25621 cgtccacctt ttttaaagga ctcaatcgtg ttagcaatca ctggttcgat acttgtcagt
    25681 tctttttcaa ccgcagcggc cactttctga tcttctttgt tcattagttg aacggcttga
    25741 gaaatactca tctcatctaa tccaaaagtt tcttggtttc tgcgttccgt tgttaggttc
    25801 tctaaattga ttttgctcat ttttatcttc cttcttttct tataaattga tagttcatac
    25861 cagctttgat ttggttgatc aatggtagct cttctttgat aactttagct actacattca
    25921 ctttttcatc cgctggcaaa tcatatttgg ttaattggat ctcacccata tagcgcaaat
    25981 acttttcgtt atctaaagta atagaccctt tcatacgcgt agctgtattt cttgctggga
    26041 taggcggaat ctctcgaaaa cgtgcatcta cgcttcgtat gacatctctt gcatcgtctt
    26101 gccgattcgt atgcttccct aatatatatt cgtaaaattc ttcatctaca ggttccgtat
    26161 ggagcaagac tgtctgttct ttttggaaag aagcaaattg ctcctgaacg ttttctgaca
    26221 gacctgcatc tccgatgtaa acaatatccg tgttacttgc taatagatct agagcgcctg
    26281 caagaggatg gatccctcga tgttcttcca aagttggcaa tccttgatat agtgggcctc
    26341 tcaactctgt atctcctggt acaaaacctt ggacaaggag accttgaatt ttgagccatt
    26401 gatttttttt ctgataccat tctttgtcca gccctgtttc gggacgtgga taataattat
    26461 gccaagcttc aatctgtgag aaatcagctt ctgcttcttt caattcatcg atatctttag
    26521 gcgtgatcgt gctagcattc aaactgattt tcaattgatg tgaccagtcg gcaatctgct
    26581 gattggaaat atgataatcc attcttaaac ctgttacacc aattgctttc aaaggcgtta
    26641 gatcttctaa tgaaaaaccc gctcgttcca atgcctctcc tgaaatatcg accatcaatt
    26701 ctagtttatt ctttttcgct tcgcttccta gttcgatcaa tcgcttttga tatgccgaaa
    26761 catcatcttc tggtatatgc atggaagtga aaataccgac aaagccattg gatgccattt
    26821 ggcggatata ctgtttcttc tcttctgaca aagaatcgtt cataaatatt gaaaagccaa
    26881 acatattatc cctctttttc tgtatccgtc ttcatttcta tgactagagt atatatctaa
    26941 agaaacaaaa tttcaatact tttattaaaa taattaaatt tcatttctaa aggttgagtt
    27001 tatattatca aaagaattgt cataacctaa aaaaggcact gctaagcaaa agcagtgcct
    27061 tgaaatattt tatttaaata acacaaaaac ataattactc ataagaaacc aattctgtat
    27121 tatctaccat gaatgtaaag aacccctcat taggcatcgg atgaaaataa gcattgatca
    27181 ctcttatcaa ggcattatgg caaactaaca gatagacatt ttcttcgtct tcgatgcatt
    27241 ctttcaataa aggaacgatc cgtgcataca catctaagac tgactcccca tttgggaatc
    27301 gtacagcgaa cgctaaacgt gctttttgaa agttctcatc tttgcttggc agtccatcat
    27361 aatccccaaa atccatttct accaatcgtt catcaacggt cagcggcaag ctgagacgat
    27421 cagcaactgc ttgtgctgta tctcttgctc gttgaagagg ggaatggatg attttcgtga
    27481 ttggaacagg caaatctact accttttctg ctagtttctg tgcctgcatc tgtccttttt
    27541 cagtcagcgg cacatctgcc cgtccgcaaa ctaatccttg tgcgttccaa gttgtttctc
    27601 cgtgtctcgt tacataaagc atgtgattct ctccttcgtt ggcaaagttc cccttaacca
    27661 taccttgttg ttcttgagat tacaagggtt agattctctc aagagaaata atctcagtag
    27721 atactttatc caggaaggtt tgatcatgtt ccactagtaa catggcaggt ttcacgttca
    27781 agatcagttg ttctaattgt tcttgattga agacatccaa ataattcaat ggttcatccc
    27841 atgtatatag ttcagctggc tgtgataaag atttagccaa ttccactttt ttccgttggc
    27901 ccatactcat ctgctcgatc ttgttatgaa aaacatctct ttccatccca agctttcgga
    27961 ggttgttcaa aaatgcttgg tagtctactt ggtttttctc tgcaaattcc gccaacgttc
    28021 ctcgattgtc ttcataattt tggcttgcat aactaatgct cagatgtttt ggctggtatt
    28081 tttctcctat aaccttgccg ttgaatgccc ccagaagata atggataatg gatgactttc
    28141 ctgcaccgtt aggacctgaa atcgccaccc gctgatgagg ctcgattgta aaatgaattg
    28201 gctcgaataa cagattttca taccctaatt gaagatcttc tacgcttaaa agtcgcttat
    28261 ggtgagacgc ttggctattc atcgtcaaag aatcgatata ttcgatatct tttaatagtt
    28321 tttctttctc gctgatctgg gtctccatcc gattcacgat tgctttggat cgtttcatcg
    28381 tccgtgcagc atcagcaccc actgctcctt tattcactcg tctagattca gtatcgatga
    28441 atccgacttg tttctttgtt ttatctcctt ctcgggaacg agaccattcg gctttttcag
    28501 ctgctgtttt ctttagccta ctgacttctt ttttcaattt ttcattttga gccatttcaa
    28561 attcatcacg aagttttttc tgttcttcat agatagagaa attcccttga taaagttcca
    28621 gttgactttt ttcgattgct aaaacatggt ccactacttc atcgataaat ccccggtcat
    28681 ggctgaccac gatgaagcct tgttttttct ttttcaaata agccgctact tgttttctac
    28741 cagagatatc caaatgattc gttggttcat cgattaacgg gaaatgagtg tcatccacaa
    28801 ataaaagtgc cagtaggact tttgtcttct ctccccccga tagtgtgctg aattctctcc
    28861 ataagatttc aggatctgtt tgcatcaatt ggagctctct ttcgatttcc catatctcaa
    28921 aatccgtaat atcatttaac acgtaatagg ttaaacgttc tttatctttt gtctgttgcg
    28981 ggaaataggc aaattcttgc tgatggatta cttgcccttg ataaggtagt ttgttttgta
    29041 gaatattcag taaagttgtc tttcctcgac cgtttcgtcc gataagtcct agtttccatt
    29101 gtgtgtcaaa atttagattt gcttgttcaa ataataatgt gccttggctg tcgtagccga
    29161 atgtcagatt ttttatttcg attttagaca ttttccatca cctcgtaaaa aaagaccagt
    29221 cctattttca gaactggcta aagaggatgc aagggttgga tacacacaaa aagacccata
    29281 catcgaaaaa accaagccaa tcccgaaaat ctgcacactg cttccttgtc tccacaaggt
    29341 acagtctgaa tgcagctttc atcaatcgac ttaatttttc aatgcacgga tccctcactt
    29401 tgtcctatat ttgaaattac gatagcataa agaaaatgat tttgtcaact acttcgggag
    29461 gatggtgaaa aatctgctaa gtgtctgtcc taagattttt gttttttcta atgtttgcct
    29521 gtgttccatt gcttcttcta aacctattgg acccaaatga atacttaaga caattgggag
    29581 aaaatcagaa agtccttcta gctcttggtc tctacttccg caaatagcga ttattggttt
    29641 tcgatatttt tttgcaagca ctgctacacc gtatggaact tttccgtgga tcgtttgctg
    29701 atcgatccgc ccttctcctg taatgatgac atctgcttgt tcgatctttt tttccaatcc
    29761 agtgatttgg ctgactaaat cgaaaccaga aaccatcttc gctcccaaca aaaaaagggc
    29821 tccaccaata ccgcctgctg ctccacttcc tggaatatca tctaaatcca cctcccagaa
    29881 atcttttatt tgctgagcaa tctttcctgc ttgtttatct aagaaagcta gcgtcgtatc
    29941 tattcctcct ttttgtcttc caaattgcca agcagctcct tgttgacctg tatatggatt
    30001 ggtaacatct gcagcgataa tcaattttac tttagaaaca agaacgtttc ttcgatcaaa
    30061 atgaagtttt ttagtagata ataaaggatt tccttctgtg tacccttcta aagaagcacc
    30121 caaggattgg agtaatccta gaccaccatc gctacacccg cttcctccta aagtgacaat
    30181 aatttgttct acttcttgaa gcagtgcatc tttaataagt tctcctaagg cataactgga
    30241 agcaagtcgg atagtttgat ccgttggttt atcaagtaga tctaacccca atgcttgtgc
    30301 agattcgatg actgcggtgt tttttccttg ccaagttgtc aataaatagc tgatttttcg
    30361 ctgacggaat aagagatcca tcccatcaat ggtacgccat gttcccctga gcgcgtaata
    30421 gattgcttct gcagtatttt ctccgccatc tgcaatcggc acattgattt ttcttccttt
    30481 acgatcttcc cagccattta gaactgcctg atttagttca aatgaagaag cacttccttt
    30541 aaatgaatca attgccgcca aaatatccat ctgtatccct cactttcttc ttaagtaaga
    30601 cacttttttt catttttttc aaacaaaaca atgctatttt cttccatttt tctatatact
    30661 aaaagggaac tcattgaata aaggagagaa aaaacatgaa aatcgcaata gctggggccg
    30721 gagcaatggg cagccgaatc ggattgatgc tacatcaaag cggaaatgag gtcctcttga
    30781 tcgatcgttg gcctgctcac attgaagcca ttcgtacaaa tgggttgatt gctgacttta
    30841 acggtaaaga agtggtcgca aaactgccaa tctattcacc agaagaaatc atcgaaagca
    30901 acgaacacgt ggacttgatc gtagcattaa caaaagccaa tcaattagat gatatgtttt
    30961 gttcgatcca atccattatt actgacaata cttatgtttt gtgtttacta aatggattag
    31021 gtcatgaaga tgtactggaa aaatatgtgc caaagaaaaa tatcttattt gggatcacga
    31081 tgtggacagc tggtctagct ggtcccggaa aagtcacatt gttaggtgat ggagaaatcg
    31141 aactagagaa cttggaacca gaaggcgaag catttacaaa aaaagttgta gaagtctttc
    31201 aagaagcaaa tttaaatccg atctatagcc ataacgttcg ttattccatt tggcgaaaag
    31261 cttgtgtaaa tggaacattg aatggtttat gcacgatttt ggattgtaat attgctgaac
    31321 taggcgcgca aaaagcggca gagagcatgg ttcgaacaat cgtatctgaa tttgcttcta
    31381 tcgcagcaaa agaaggaatc atactagatc aagaagaagt gtaccaacat attgcttcta
    31441 cttatgatcc tgacaacatc gggttgcatt acccatctat gtaccaagac ctgatcaaaa
    31501 accatcgttt gactgaaatc gactacatca atggtgccat ttggcgaaaa ggacaaaaat
    31561 atgatattgc tacaccatat tgtgcctttt tgacccaatt agtccatgca aaagaaggaa
    31621 tccttggcgc agaataaaag gctctctgat gagaatcagc tgaatcagca gctggttctc
    31681 tttttttaag cccaataaaa gatcaaaaag aaaacacaac tctcatgatg ccataagaat
    31741 tgtgcttgtt tgtttcagta cataatctct tcaaaatgta ggttttttat ttgttttcaa
    31801 cagaggagag gtcatattcg tattgctcat aaatagtgga atcgttagtg ataaatcgtt
    31861 ttgcccaatt ttctgcatca taaaattcca atagctctga taggattggc ttaaatggtg
    31921 tatgcagaaa ttccggtaat tcatctaaat cacgttctcg aagcaaaaaa atattttcag
    31981 gacgataaaa atgataatga gcaatcgctt gattatccgt cactagtttc ttttgaaaat
    32041 acatggattc aaatgtccgc aaagtcactc cttgctgacc ctcccgcaac agttccagaa
    32101 tcccgcgcga ttcccctgtt tttttcaggt actcttcata agtaagatat ccaggttgtt
    32161 cattccctcg atgtggaaga atgaaatagt tggtcgtaac atctcttttt ataaattcct
    32221 gcttatagct ttctgctcgt tcttttctcc cattattcgt tgcaccaaaa aatagatccg
    32281 tctttggttc gctagaagaa aaattcatat gtttcgaata aaatgaacta ttatgtttca
    32341 gcccaagttc ttttgcttcc aaaaaatcaa aatgataaat ctcatcgatt gccggttcat
    32401 cttgtgcctg cttcagcatc gcctcgtgtt ctgctttgaa gtgattccaa aaaaataaca
    32461 caatttttgc attggtaaat gggcgcacgc gtcgagccat ctccatatca aatccataat
    32521 ctaaaaaaac gatcagctga taatttgcca actgttgtct agctgattta atgaattccg
    32581 actgtagtaa atcttttccg gaccaaacat ctaaagagcg gatggaaggc aaaaaataaa
    32641 gtgatttatt ttttgcaact agcagtacgt catttttgtt catcttttcc gcctcacttt
    32701 ctctgtcact ttttcctatg atagcctgtt taaatagtaa aaagccagta aaacgtttcc
    32761 tatatttgta tgaaaattta acatttgtat gaaaatatga tgaaataaat cattcttcta
    32821 ttaaaattcg cctaaaagtt ttctgaatag ttgtaattgt ctgaaaattt gttatcatta
    32881 gtcattgtta aatattgcta tttattctta atataaattt tgattgtgaa tttaaaagaa
    32941 agaggtcatt tatggaagat aaaaaattga aaaaacaact tagctccaga catatcacca
    33001 tgttagcttt aggtggagca atcggtgcag gtctatttaa aggaagtggc gaagcgattg
    33061 ggatcgccgg cccttctgta ttgattgctt ttttgattgg tgggctgatt ttatatatcg
    33121 tgatgaaagg tctgggaaaa atcgttttaa gcggtggcga cacgcatcac ggattatctg
    33181 gtttgatacg cccttatcta ggtgctcatt ctgctgattt tactgattgg gtctactggt
    33241 ctatgtggat tatcaatatc atcgctgaag ctgttgcagc tgcttccttt ttgcagttgt
    33301 ggttcccgca cattccagcc tgggtatttg tttttatgtt ggctgtttta actacgatca
    33361 tcaatcttta ttcggtacgg ttattcgcag aaacagaata ttggctggct tttgctaaaa
    33421 tcagtgtcat tatcttactg atcatttttg ctacttatct tgtcggtcag caaatgttgg
    33481 gcacaggcgt tttccctacc cttcagcaat tgactgacca tggtgggttt actcctcatg
    33541 gtatgaaggg aatcatcagt tctttgcttg tagttatcta ttcttacggc ggttctgaac
    33601 tgattgctat cacggtaagc gaagcagatg atcctaaacg tgcgattcct aaagcaatca
    33661 aaggtgtcat gggaagaatc atttcctttt acatcattcc tttgtttttg cttttgattc
    33721 tttttccttg gaatacttta gcaggcacga atgtcagtcc ttttgtgatg gtatttgaaa
    33781 aaatgaatat cccatttgca gcggatatcg tcaattttgt gattgtcctt gctttgttct
    33841 catctatcaa ttcgggtgtg tatgcatctt caagaatttt gttcttccgt ttgaaggatc
    33901 gaaaaggttc ctctagaaaa ctagctgttt taaacaagca tcaagtaccg caacgtgctg
    33961 ttttattttg taccagtgtt ctttatcttg gtgtagctct ttcttatttt gtcggtgaca
    34021 aattatttgg ctatctggca ggttcccttt cgtatacagt attattgatc tggatcatta
    34081 tcagtgcggc atcctttgta ctggcactaa gaaaaggaac attatgggat aaaggaatca
    34141 gcttttttgc attagctgtc ttaggattga ttttccttgg tatcctgttc acgaactcca
    34201 ttggggtaac tgtattgact ggcctgcttt acctgttcat ttatttcagt tatcaaaaaa
    34261 agaatgatgc gttcgtattg acgaatgaat gaaatcgata gaaaatttta ttttatttat
    34321 gtggaataga tggagctatt gaagaaagga gttgtgacaa aagtcttgtt gcaactcctt
    34381 tttccgaata aacagtctca tgacctcttg gtaaacggtg ttcaaaaacc ctctgtgcaa
    34441 aataattgat tgttctccat gctcatgaca tgatagaaga aaggaatgaa aaaaaggagt
    34501 ttgttttaaa tgaaaaagta ttggaagttt ttgttgatga tcggtgtttc aacggtagtt
    34561 atgtttggta tgatgtactt gaatgtctat gcgctcgatc atatcttctt cagtcgtaca
    34621 cgagtattca tggcgttgat gatgggtgca gtcatggcag tcatcatgct gttgttcatg
    34681 tggaaaatgt atgaaaacaa aaagataaat gttatgatct tagccgctag tcttcttgtt
    34741 tttgccggtt ccttgtttat ggtacgaagc caaactactg tcaacgacac agcttggatg
    34801 aaggccatga ttcctcatca ttctatcgct atcctggcaa gtaaacgagc tgatttaaaa
    34861 gatcctgaag taaaaaaatt agcggaagaa atcattcagg cacaagaaga agagatcgac
    34921 aaaatgaaaa aaatgatcaa agaaatggaa tgaccattat ccgtccaaat aaaaaaagag
    34981 gatgttccag aagttatcag cttcaagaaa taagaagaag ctacttctgg aacgccgtga
    35041 ataaggggtt gtgaaaaagc tgccctgcat caagtaataa gaacagccaa acaaaaatag
    35101 cttctcctat ttttcgtttg gttaggctta ttaccgcaga tgcaagcttt tgaacaccgt
    35161 ttattaagag gttgtaaaat cagcgttctg acctgagtat tagagagaca aatggaaaaa
    35221 tagttcctca tattttgcca ttttttgagc taataccgag ggtcagctga ttgaacaccg
    35281 tttatcgaga ggttgtgaaa aagtcgctta gtttcgcgta ttaagaaaaa ttttgtgaaa
    35341 tggctttcca catttttgta taaatttggc ttaataccga gaaactggct tttgaatacc
    35401 gtttattcgt aaaagggatt gtgacaaaag tcttgtcaca atcccttttt atgtttttat
    35461 tgttctaatt gcgctgtctt gcttactgct tcttgcggtt tcacaaattt ttttgagatt
    35521 ccccaacctg tgaaggcact gaccatcgaa aacacaggag aaagcaaact gaaaaatacg
    35581 aatggcaagt aagtgagtgt aggaatacca aatgtacttg ctacgaaact tccggcaatt
    35641 ccccaaggca ctaagtagtt gattactgtt ccaccatctt ctagcgttct acctaataca
    35701 gttggatcaa atcctgcttt ttcataagtt tctttaaatg cattaccagg cagaataaca
    35761 gataggaatt gttcaccaat aaaaatattt actccgatac ttgtcatcaa tgttgtaaaa
    35821 atcaaatttg gtgtgttcgt catctttctt gatactcgtt ccatcacggt tgagatcaag
    35881 ccaaattcga tcaacaatcc acctaatgac aaagttagaa taatcaatga cacagtaggc
    35941 atcatacttt cgattcctcc gcggctaagc agtgaatcga tttgttggtt tccagtattt
    36001 gaaacaaacc ctgattcgat gaccccagcc aacttcgtta aggaagtttg tgggttttga
    36061 ataaaaatca ttcctactgc tacagcgata ttcaacaaaa tcgttaaaat tgccggcacc
    36121 tttttccatg cacacagtaa cattaaaaat aaaggaatca gtgaccagat tgaaatagta
    36181 aagtttgctt ctagaacatc agtcacttca cgaatagatg aaagacttgc ggctttactt
    36241 gtgtgtccta aaatcatgaa taaaaagaaa gaaacaacaa atgccgggac agttgaccac
    36301 atcatatgct tgatgtgttt gaacaaatcg gcatcaacaa tagctgctgc tagatttgtt
    36361 gattcggata atggagacat cttatctcca aaaacggcac ctgaaacaat agctccaaca
    36421 accagcgctg gatttaagcc tagtgttgtc ccaataccga aaaatgcaat cccaatcgtt
    36481 gacataacag taaaggcact ccctacagcg ctacctacga ttgcacacac aacaaataca
    36541 gaagggacaa accactggac actgatcaat ttgaacccaa tgaccattag agttggaatg
    36601 atccctgctt gtatccatac agcaatcaat gaaccgacta aaataaaaat aaagattggg
    36661 atgattcctg gtttgatgcc attgatgatt ccttcgtgca gccaatctgt cgggtatctt
    36721 tttatcactg catacaacat gaccattccg atcgctgcta agatcgtgat attaggtgag
    36781 acctttaatc cgacaacgcc aatcgcaatg cctaaaacaa taaccattaa tacaagtgtt
    36841 gcttctaaaa aacttggtgt tccttttttt cccatgataa tctctccttt tttagttgtt
    36901 cttatgttct aaaaaagtta agatatcgga ttactccgcc gcaattcatc cgcgattcct
    36961 cctttataaa aataaaaaga cctgttttaa actaaggacg aatgactccg cggtaccacc
    37021 ttaattaaaa acagatctgt ttttcacttt caaactttta ttcaaatgta tggactttcc
    37081 atgtaattcg tcaattaggc ttgatcggtt cacagcgacc accgactttc tgaacaaaac
    37141 acctaaccgc tactgcgtga aaagttgact tgtacgaagt ttaccttcca taagatcatt
    37201 tgtcaatgaa aaagaaaata ttttttcatt tttctgaaaa ttatttttat aactttcaca
    37261 cacaagttta ttttttacta gaaagtagcg ccctcttgtt tttttcttgc tactatttct
    37321 tgatgttctt gcttgattct ttctaatagc tttggctctt tcaacagatc aagagctgta
    37381 ttggcgagta gttctgctgc aatcgcaata gaagcaaggc ctttgtcact tttagcagca
    37441 gctttgaatt cttctgtgtg tccggcaata tatgtctcag agattgctac cgtaggctgg
    37501 attgttggta tgacttggct gacatttcct acatcagaag aaccgagact tgttctttgt
    37561 tccgtttcta tttcttcatc tggaacacct gcttcttttg catgctggaa gaataagtca
    37621 tcaaaagaag gagtaacgat gacatcatca actgcatttt ggaacaatcc aaactcaaaa
    37681 gtcgtgcccg tacttatcgc agcacctcgt acgatatttt ccactttttc atatacttta
    37741 tctaatgttt gccgatttcc tgcacgtaaa tagaaacgtc cagcagcgta atctggaatg
    37801 acgttggcag ctactcctcc gtctgtaatg atcccatgga tattgacatc ttttggcaat
    37861 tgcaagcgta gagcgttgat tccattaaac acttggatca atgcttccaa agcatttact
    37921 cctttttcag gtgctgctgc tgcatgggaa gcgacaccgt aaaatttgat gtcgactgga
    37981 tcattcgcta aagattctgt cgttttccca taacgaaaag ctggatggac gcataacgct
    38041 acatcgacat cctcaaaaaa accttctcga acaaagctgc ctttagctga tccgttctcg
    38101 cccccttctt cccctggggt gccatataca cggatttctc caccagtttc atcaatgaat
    38161 tgcttcacta tgctggcggc taatacggag taagtaccaa acaaattatg cccgcatgca
    38221 tgaccaatac ctggtaaagc atcgaattct gccaaaaagg caattgtggg accgggttta
    38281 ttggaaatat aacgtgcatc aaaggctgtt cggtgtccag ctacttcttt ttctacccaa
    38341 aacctttctt tttctaattg tttaatcaac gctgctgagg aataaaactc atagttactt
    38401 acttcaggat gttcgtggat atctagagca agtgcttgat attctggtaa acgatattgg
    38461 attagatcct tcaattggtt tgttgagatt gttgttgtca taaaaaattc ctcctatgct
    38521 agtcattttt cttattttct cccgaatgtt tcccatgcag gcacgcttga tccttttgat
    38581 gttttctcga ttactttgac tgtgtcttct gtttgataag cgtctactat tttttgatac
    38641 gttttattgt tttcatcttc ttttcttgca acgatgatat tcacataagg acgtgcatgg
    38701 tcatccactg gttctaagaa gatggcatca gaagcaggat taaatccagc atctacagct
    38761 acaccgctat tgatcactga aatgtctaca tctgacaaag cacgtgctgt ttgggaagca
    38821 tctaattcag aaatgtctag attttttcta ttctcggtaa tatcagaaac agtgggcgct
    38881 tgtccttttg ccttatccac tttgatcaat ccagcagttt gcaataacag aagagctctg
    38941 ccgccatttg taacatcatt agggattgct acttttgctc cgtctttgat atcagctaca
    39001 tccttcaaag tgttagaata aattcccagc ggtgcattga cagtatttcc gatcgatact
    39061 aaatcagttc cgtgttcttt attgtaattg tctaaaaaga attgatgttg gaaagaattc
    39121 aaatcaatcg atccatctgc taaagccaca tttggttgat tgtaatctgt aaatttcacg
    39181 tattccaaat taatgttctc ctttttcaaa cggtctttca cgttgtccca tacatctgta
    39241 tcttctccaa taatccctag ttttacgata gtttcttttt tgtcagttgt atctgctttt
    39301 ccttggctac accctgccaa ccaaataatt gctacaaatg taatgactac aaaacgaata
    39361 atttttttca ttttttctcc tccactttca atgtgtaatt tttttaatca gttgattact
    39421 gataaattga cttaaaaaaa ctaagattag aatcaataat gtagccacaa tcgttacatc
    39481 tgtttggaat cgattatacc ctctcgatat agcaagattc cctaatccgc ctgcacctac
    39541 tgctccagcc atggtagtca gtccgatcac gttgatgata gtcaacgccg agacccgaat
    39601 gataccaggc aaaccttcta acaaatacac acgtaaaatg ataccgattg gactggttcc
    39661 catcgcttct gccgcttcga tcaccccagg atcaacttct agcagtgcgt tctcgatttg
    39721 acgagcaaaa aacggaacaa ctccaaaaat caatggcact aaagctgctt tcgcaccaat
    39781 cgtcgttcca actaagaaac gagtagtcaa tgctaaaaga gaaagcaaga taatgaaagg
    39841 gatggaacga atgatattga tcagcttatc aagtatttca aatagcagac ggttagctag
    39901 taatccatta gggcgtgtca ctactaacgt cacacctaag atgattccaa tcatcccgcc
    39961 aatgaatgct gtccaaaaag acatatatag tgtttgcttc gtcgcttcga caaattcatc
    40021 cggaatcaaa taaacattgg gcaaatatgt tttaaagaaa tcagtcattt tatcttcctc
    40081 cttcgatcac tttgatacga ctatctaaat cgtttttttg taaaatattt atttttacac
    40141 cagatttgat caaataatcc aatgcttttt tccgctgttt ggtttctcca gctaaagtaa
    40201 cgatcaaact ccctaacggc gtttcttgta ataactctac attgccatat aaaatattcg
    40261 ctgttacttg atatttgctg tacagatgag cgattagagg ttcgttcgtc tgatttccaa
    40321 tataacttaa ttccaccagc catttattgg cgatctgatc ggcaaaagca gaatgggcaa
    40381 tgatcgtttc taatgcttgg tcaagatgag tagctgttcg aataaaatct ttggtcaatt
    40441 cttcttcagg attgctgaag atctggatgc tgctaccttt ttcaacgatt cttccatctt
    40501 ccataaccgc taccttgttg cagatttctt tgacaacttg catctcatga gtgatcagga
    40561 cgattgttaa acctaactgg cgattcaatt tttttaacaa tgcaaggatc tgaagggtcg
    40621 ttttcggatc aagtgcactg gttgcttcat cacataataa taccttaggt tcattcgcca
    40681 aagctcgtgc gattgctact cgttgttttt gtccccccga cagttgttta ggataagcag
    40741 atgctttttc ttccaaaccg acaagttcca gtagttcatt cactttttga cgacgttcct
    40801 gtttcgattt tccagaatac tttaaagaaa aatcaacgtt gtcaaaaata gttcggcttt
    40861 ccattagatt gaaatgctga aagatcatac cgatggcctt tctttctttt cgcaattctt
    40921 tgggagagag ctgactcaga ttcgtctgat tgacaatgac ttctcctgct gttggtttct
    40981 gcagcaaatt catcacacga actaacgtac ttttccctgc acctgagtaa ccgacgattc
    41041 cataaacatc gcctttttca atcgttaaat ctacagaatc tactgcctgt atctcttttt
    41101 ctttttgttt gaaacataca gaaacatctc gcaattcaat cattaaaatt cctccttatc
    41161 taaaaaaagc gtcctcaaga aaatgaaaat gtcattttct tgaggacgct tttttgcgtg
    41221 ttaccacctc atgttcaagc tgtgttcaca cacaactcct cttcaagtac gatcatactc
    41281 tagcaagata tcggtcgcag ccgtcatcgc cttacatcta tgctcgggat gaattgctcg
    41341 atggccattt tccaatagtc gttccttgct tcttctcagc taccgaagct ctctgtcaaa
    41401 ggttcttcta tcgtacttac catttcaatg caaataatat tcaaaaaaaa agtcctttta
    41461 ctaacataaa ctatgtcagt aaaaggacga cgtatcgcgg taccaccttt tttcggaagt
    41521 ttccttccct caagcccaac atctcaaaaa gagagattgg cgttcgtttt aacggtcgaa
    41581 cagttccgaa tttgcctact tatcgacaaa ttattctcca aggccatttt cagcttttct
    41641 tacttgactc ttctcaccag ccagagcctc tctgcaaagt ttccaaactt actttccttt
    41701 tcaacgaaat cgatattttg ttgttgggat taatctacat gaggaaaact gaaaagtcaa
    41761 gtacgaaatt caaattattt tttctatatt tatttttctg tttttttatt taacatttca
    41821 ataacagttc gaagatcttt tccttccgca agaagtttca atttttcctt ttcttcgacg
    41881 gtataatttc ggacaaaact ggaatcaggt atcaaaacaa cgcctaatcc tgctcgtgaa
    41941 gcagctgttg ctcctactaa agaatcttcc actgcaaagg ctgaactagc ttctaatcct
    42001 gttcgttcca aagctgtcag ataaggaatc ggtgaaggct tgttctccga cacttcgtct
    42061 ccgaatgtaa acgtgtccaa gtaatcagct aatttaaagt gatccaagat atctgttgct
    42121 cttttcgtaa cagtggtcgt agcaatgcct agtttcatat gacgttcttt taagtctgcc
    42181 aatatttctt ttgcatatgg ttttaagtgg atggctccgc ttgtcagctg ttgataaaaa
    42241 tattcttcac gcttcgctcg gacttcctgt actttttcag ggctacctgc tgctttcact
    42301 aaaatatcaa aactttgttt ccagtttttt ccgccccaag cgtcaacgat ttcttttggg
    42361 atatggatat caaattgctg aaatccccaa agccagccat cacgatacgt tttttctgtg
    42421 tcaactaaca aaccatctaa atcaaatatt gcacctttca tctatacatt aatcctttcc
    42481 aaaacaatac acatagttta gcacgactgg tccaaaaaga acagaagcaa agaaccagcc
    42541 ttctcgttta taagagttct tggaatcgac ggatatagat tttcttcaca gctgtcacaa
    42601 gcgccagata agcgatgact gtagcaaata accataacca gtaattgcca ggaagtggca
    42661 tcaagcctaa ttcagcacca aaacttgtaa aaggaaggac agaaccgaca ataattccta
    42721 atgtagtgat aacaaacatg gcaaatgttg cgttgctttg gataaatggt actttcggtg
    42781 tacgcagtgc atggagcact aaggtttgtg tccatagtga ttcgacaaac catcctgcat
    42841 ggaataatgc gatgaaaatc actcgctgtg aactatccaa tgtatggaaa cttccgccca
    42901 ctacagcagg acaaataaca aaatacatca acaagtaagt agtaatatca aatatcgaac
    42961 ttgttggacc aaagtaaacc atgaattccc caatactaga tgcattccat ttttttggct
    43021 cgtccaaata ttctttatcc atccgatccc atggcaagga aatgcaggaa acatcataga
    43081 tcagattcaa aaacaaaagt tgtaaaggca gcattggtaa aaatggcagg aacgtacttg
    43141 caatcagcac ggaaaacata ttgccaaaat tagaacttgc tgtagccttg atatatttca
    43201 tgatattccc aaaagtttct cgtccagaaa gaaggcctct ttccaaaatc gtcaaatctt
    43261 tttctaaaag gatcacgtct gcagattctt tcgcaatatc cacagctgta tctacagaaa
    43321 taccgatatc agccactttc attgcaggag cgtcattgat accatctcct aaaaatccga
    43381 cagtatgacc atttttacgt aaagctgtcg tcaaacgtgc tttttgctga ggattcaatt
    43441 ttacgaatac ttcatggtct tcagctactt gtgctaattc atgatcactc atttccgaga
    43501 ttttctcacc ggtaaccaat tcattgatct ctagacctac ttgacggcac actgaacgtg
    43561 taactaattc gttgtcccca gtcagaactt ttacagctac accatgttct ttcagagctt
    43621 tcaacgcttg tttcgttgtt tcttttggtg gatcaaggaa agcaagataa ccaatcaaaa
    43681 ccatgtctga ctcatctttg actgaaaatt ctccaacgac gcttggattg gtcttttgtg
    43741 cgacaccaat cactcgtaag ccatcttcat taagtgactg tacttttgca agtacggctt
    43801 cttttcgttc ttttgttaat ggtgtaacag taccgccaag atcaataaat ttagaaatgt
    43861 tcagcatttc ttcaatcgcg ccttttgtga tcatttgtgt tttaccagct ggatcagcaa
    43921 ccacaacact catacgacga cgttcaaaat caaaaggaat ttcatccact ttttgataat
    43981 tgatcttatc tgtatctaaa gtttctgttg cttcatcaat gatagccaca tctaacaaat
    44041 ttttcagccc tgtttgatag tagctattta gatacgcatg gcgcaaaaca cgatcatctt
    44101 catttccttc acaatccata tgatattcaa gaatgatttt atcttgtgtc aatgtccccg
    44161 ttttatccgt acataacaca tcgattgcac caaagttctg gatggcattc aaatttttga
    44221 tcactgttcc ttttttggcc atcacacttg ctcctttgac caaattcgtc gtaacgatca
    44281 ttggaagcat ttcaggtgtt agaccaactg ctacagatag tccaaaaaga aaagcttcta
    44341 gccaatcccc ttttgtaagc ccattgatga cgataactgc tggagccatc aatgacataa
    44401 atttgatcag tagcatggat gttttatgga tgcctaattc aaagcttgat tgaattggtt
    44461 tttcagatag cgtttctgct acatgaccaa atagtgtttc atttccaaca gaaacaatga
    44521 ttccttccgc acttccactg atgacattac ttcccataaa gacaagattt tcgtaacttg
    44581 tttcgctttg ctgatcgtct tcacatactt tcgcatgctt ttctactgga tagctttccc
    44641 ctgtcaatgc tgcttgggaa atgaataaat cctttgcgga caataaacgc atatccgctg
    44701 gtatcatatc ccctgctgaa agccgaacaa gatctccaca gacgatttct tccataggaa
    44761 tctctgtgta ctttccatta cgttttacag ctgccgttac tttcacaagt gatttcagtt
    44821 tttcagccgc ttgattggaa cgtacggact gaatcaacgt cattgtcccg ctgacgataa
    44881 ccatagtgaa gataatggct acaccgaaaa gatctttatc tccaggagct gctaatacat
    44941 attccgtgat gaatgaaata attcctaatg cgatcaacac taatgtaaat ggcgtgatgt
    45001 atgctttcaa tatttctaca atgaatggtg tttttttgcc atatgaaatc gcattttcac
    45061 cgtaattttc tcttgaacgt tcgatttgtt cttctgtcaa tccatttgct gatgcatgga
    45121 atagttcaaa taattcttgt ttcgtttttc cagcaaaagc tgcatagatt ttttgtgtat
    45181 ctttcttttt ttccatctca atctctcctt tgtgtccaaa agacagctgt tctcgctgct
    45241 tttggtcttt agctattcat cggatcgata gagaaaaaac tgaaaggggc tgagaacaga
    45301 tagataatag ccctggcctt tcctctagat ccttgttttt cgaatgactg tcatccattt
    45361 gttctcatct cctttactaa gtaattttaa ttcatgactt ccaatcattt ttcgaatagt
    45421 tatttttcca attagaccac ctccttttta tttttcaccg atggggattt gcggcaacaa
    45481 aaaaacctct cgccaaatac tcagcgaaag gtttgaaaaa gcatattaaa aaaagcttct
    45541 cagatctcat cgttgagttt tgacactgta caacgtaaaa agcagatacc tgcttttagc
    45601 taccttatga aaagccttat ctcgacaatt cctgttctac ccattggcgt ctctcgacgt
    45661 ttttgggcag tagcctatgt ttgtatagga gcctcaccta acaaatctta ttcggttttc
    45721 cttcgttaat ataacaacta aaaaagagga tgtcaaatca attttccatg tttttcatac
    45781 tttttttaaa atacacacgt tatattcctg tctcacgcgg ttttatttgt ctcattttcc
    45841 acctcccgct ataatagaaa tatagtagga aacgaggtgc tgttatggaa agaacacttg
    45901 ttattatcaa gccagacggc gtgagacgcc atttagtcgg aagcatcatc caacgttttg
    45961 aagcaaaggg actggccatt gctgaaatga agtttgaaac tatgactcct gaattagcaa
    46021 aagaacatta tcagcacttg actgagcgca gtttttttga tgaactgatc gattacatga
    46081 cttccggtcc tgtcgtttat cttgtgctgg tcggcgagga agtgatcgat atcgtccgta
    46141 agatggttgg agcaacaaaa gctgccgatg ctgttccagg tacgatccga ggagactacg
    46201 cgctgccggg gactgaaaac atcattcacg cttctgattc ccgtgatgct gcggtaaaag
    46261 agatcgcccg ctttttcccg ccattcgata taaacaaacc gtctgaaaaa gcggcgaagt
    46321 gatacaaatt ctaaactgct ggtctagttg ctgggttcag caatggccag cagttttttc
    46381 tctaaggacc tccgttgatt ctttcctaac atatattcga gcactgtgaa gaattcttgg
    46441 tagtctttcg tcttttcttc ccctaaagca gcagaaatca atctttgata ataatctgcc
    46501 atcaatgttt catagatcac tgtacttctt tctttatgtg ataagctccg tttcatatct
    46561 tcattcacac tacgtgcctt tttcaaccga ccattttcta tataaaacga agtcaggttc
    46621 attaaaaaag taaagagata ctgctcatga ttgttcaact gtgctaatcg tcgcattctt
    46681 tttttgattt tcaaataatt gttctcaatg aaccgatcac tgaatatcca aggaaaatca
    46741 gctagaatag atagttcaaa ttgaccatag tctggtatct gcatcaagta ttcttcaatg
    46801 attcggcatt cataacgtaa aaattcaaat tctgtctcag atacttctgt tttttcgacc
    46861 atgtgaagat tcaaaaccaa ataatacaga tcttctgttt tcttaaaatg cctacggtta
    46921 ttgctgatct ctttataagg atcaaagctg tcttcttgta cccgatctag cattcgtctt
    46981 tttttcttta actttattgg ttcatccagc tggtttcgca tccattcata ttctgcaagt
    47041 gtcatgttca ttcgctctaa aaatgatctc aatgttacaa atgacatttt tttcactgaa
    47101 tttgtctcaa tcccgactag agaagtctta aaacagattc cttccgctaa ttgggactgt
    47161 gtcaacttct tgttgactcg aagtttcttg atcaattcac catcatacat aatagttctc
    47221 ctttttaatt taaatttttc cacattcaat aaatagatac gttaaaaagg aaaaatacac
    47281 gaaaaaaata aaaaaatgtt tttttcataa aaaataccaa ccttcaagca ttagaatgtt
    47341 gtctaactac tgaaggttgg tttgattgtt tattgattat ttttttgctg ttcaacgtct
    47401 gttcttgtta ctggatataa gttggttgtt gttttattac cattttttga aaagacactt
    47461 gtcgaatgtt cgcctttttg cttttcgatt gcttcattac gttccgcttc atttttatag
    47521 tcatattttt tcggatcaat cgtctcaaat ccgtttggca cataaaaccg caagagattt
    47581 tcctgattca gcttatctga aagacttaac gcagtcttga ctttttcctg atctttggag
    47641 atttcctcat cgattcctgc tgctttcgta tcgatgattt ctcctgtctg attattgtaa
    47701 gcttttcctc ctaggacggt gtatttgggt gtcacaaagt tcccatttcg aaaagcaact
    47761 acttgatcat gctgagaaga taataagtct gtaccaaaat gaagataatc tttatcatcg
    47821 attcccaata gatgtagtaa tgtcggcaaa acatcgattt ctccaccgta ttcatgattg
    47881 actgtccctt tagtataacc aggcatatgg atcatcaatg gcactcgttg catctgtgcg
    47941 ttgtcaaatt catcccatgt atctggatct ttaccaagag cgcttgctaa atctttatta
    48001 tctgtattcg agatcccaaa atgatccccg taaatcacaa agattgaatt ttggtaaata
    48061 ccagattttt tcaaatacgt aaaaaattgt tccaatgatt gatccagata atgtgccgtt
    48121 cgaacataat tatctactgt gctattgcca gtattcaaag atggaaagtc gaaattcttg
    48181 tcatccgtat aataaggcgt gtggttggtt acggaaagaa atttcgtgta aaacggctgt
    48241 tgtagatgct caagatattg ggcagattct ctgaataaat ctttatctaa tatcccataa
    48301 cctaacgttt cgtcggattc atcaaaataa gatcgatcaa agaaattgtc ataacctaag
    48361 tttttatata catgatctct attccaaaaa ctagctacat tcccatggaa aacagcgctt
    48421 gtatagcctt gcttttgtcc aaggatcgct ggtgcggctt gaaagacatt gtctgaccca
    48481 agttctgtga ataatgagcc ttgaggtaaa ccaaatgtgc cagtttccaa catattttca
    48541 gcatcacttg tctttccctg tcctacttca tgaaagaaat tgtcaaagct gatcgttgct
    48601 tgattctgga aaatactatt taaaaacggt gtgacttctt gtccgtctac cttcatatta
    48661 atcaaaaact gctggaaact ttctaaatgg agaacgatca catttttccc tttagcgatc
    48721 ccaaatgttt cgggatttgg ctctgcataa tgtttctttg tataatctaa aacttcatca
    48781 atcccattac tgcttgcatg cgcgcgaaca ctgctagtca ttcctgtttt gattccgtca
    48841 taaatagtat acgcatcgat tcctagatat ttgacaatat atgaacggtc aaatgttcgc
    48901 tgcagcaatt gtggacggtt ggcttcgctc agcgctagat ttcctgaaaa aataagccct
    48961 gaaagacagg taacagcgat agccatcggt ttgccgacag ggttgctttt gataggtatt
    49021 ttcttgacct tcaaccaaac cagtagccca atgaacacag cgatatccag ccagtagatg
    49081 acatcatggg gcttcatcaa agaaaaggag cttcctgaca atccttgcga cactttcgaa
    49141 aagcctaata cagatttgac tgtaatgaaa tctgtgaatt cccgataaaa aataatattc
    49201 aagtacaaca aaagcgtatt taaaatatca atgatcaaaa gaatagctaa cgctggcttt
    49261 ggctttttaa tatacaaaga aaggccaaaa aacaataagg tagtcgcaat tgggttgatc
    49321 cacaagataa agtactggat cgtaccttcc acacctaatg aaaaatctgc atagtaggca
    49381 atgatcgtct tcagccagaa aaagaaaaca gctgtcaaaa cgattgctaa acgattttgg
    49441 cacaattttt taagttgtgt cacgtatatc acttctctct attcacattt tttcttattt
    49501 tgctcctgaa aaatgaaaat ttcctaaaaa agttgttatc ttaagatttt tttattcttt
    49561 ctaaagatta ttccgtccac ttttcacagc ataaaaccgc tgcgatgtaa gcgattaaac
    49621 taatgaagag ataaaagtct tgtggtgacc gcttcactcc acggtattca aaagccagtt
    49681 tctcggtatt cgtacaaaaa aagaggctgt gacaaaattc ttgtcgcagc tccttatttc
    49741 ttgatgcagg acagcttttt cacaacttct tccttaaacg gtgttctcct gccaactcct
    49801 cggccacaag tcacaatatt tataaaacat gagaagctgt tttttgaaat tgttccttgt
    49861 ggctcagagt taaacggcag gctcaagacc tcttgataca cggtgttcaa tcagctgacc
    49921 ctcggtatta gattatgtca ggacgctaat tttacaacct cttggtaaac ggtgttcaaa
    49981 agcttgcatc tgcggtaata agcccaacca aacgaaaaat ataaggagct attttttgaa
    50041 attgctcctt gtggctcaga gttaaacggc aggctcaaga cctcttgata cacggtgttc
    50101 aatcagctga ccttcggtat tagctcaaaa aacggcaaaa tatgaggaac tattttgccg
    50161 tttgtttctc taatactcag gtcaaaacgc tgatttcaca acctctgttt ttcattgtcc
    50221 ataggattga tattgtcctt gtgatgactc attcgtaata attgaggctt gattttcttc
    50281 acttcccgtt atcgtttgtc cactgccaga atctgaagga cttgttcctg tcgactcgtt
    50341 tttttgagaa gagacagttg ttttcttgac ttgttcattt gtctttttcc attccgctaa
    50401 acgatcggcg accacttttt tgtctacttt ttcagaataa gcggtgatca cttttccatt
    50461 tttcaaacgg gctactttgt cgccatcatg agtcaaaagc aaaacggtca aatgcttgtc
    50521 tttaaattga tattgtctga gagaaatcgc actaagtacg tcatcgatat taataaattg
    50581 attttcttct tttccttttg gcaaataaat gtccaattcg cctttttcgt aattggcagt
    50641 tattttatac tccgcccacc aataagttga gaattctttt ttgaaattat ctactgattc
    50701 tttgcttgct acgatttttt ctgtttcttt ctgagcaaga tctgctgtca tttttcctga
    50761 aaatgctgcg gataaaataa gcagtaagaa aaaaccgaat aaccaaaaga gaagaaacgg
    50821 tctttttttc ctcatgcttt cctccactcc tatttaattt tgactattct attatataca
    50881 aaaaatgaaa tagaaagaca aaaaagttga aaaagatcgt aaataattga acttcttttt
    50941 cacaaaatgg taagaatgga gaatttcacg catttgctct caactattct ttcttaagcc
    51001 tcaaatccgt ttttatctga tacgtctttg aaccaatgac ccgatttttt gattgttctt
    51061 tttccatctt gtgctaagtc tactgaaata aagccatatc gattcttata tgcattggtc
    51121 cacgaccagt tatccataca tgtccacata tgatagccta aacaattggc accttcttga
    51181 atggcttgat ggacatattt cagatgagat tggacaaatt cgatccgata atcatcgtgg
    51241 atcatgccat cttctttgat aaatcgtgct tcgttttcta cacccatacc gttttcagaa
    51301 ataaagcagt cgatatttcc ataatgatct cgtacattga tcaaaatatc atagattcct
    51361 tgttcataga tctcccatcc gcgataagga ttcattttac gaccaggcat ttcataattg
    51421 tcgaaataat cctcaggcat tggaccgttt ttagtatcga ttggtgtttc ttttgctttt
    51481 acccggcgtg gctggtaata attgatacct aaaagatcta ctgtattttc tttgataacc
    51541 gtcaaatcct ctgcatggat cacaggcatg agatcaagtt cttttactat ctcaatcaat
    51601 tcacttggaa actcgccttt tacagctgga tcaaggaatg aacgattgaa gaacgcatct
    51661 gctatttgcg ctgctttaac atcttcaggg tttgattcgt ctcttggata gcttggtgtc
    51721 agattcaaga tgataccaat aacaccacct tgctccattt catggtaaga tttgatggct
    51781 aacgctgaag ccaacgcttc atgatagcca acttggatcg cttttttcat atctgactct
    51841 tctggataat gccatcgata taaataacct gcttcgactg gaacgattgg ttcattatga
    51901 gtaaaccatt tttttacttt cgaaccaaac aattcaaaac aacttttggc atatttttca
    51961 taggcttcaa ccgtttctcg gttcaaccat ccgccttttt cttgcagata catcggcata
    52021 tcgaaatgat acagattcac aaagggttcg ataccgtttt caatcaactc atcaaaataa
    52081 cgatgataga aacgaacggc ttcttcgttg attgttccag attcatcagg tatcaaacgg
    52141 ctccattgga tagatgttcg aaatgaatta tgcccagtct gtttcatcaa ctgtacatcc
    52201 tcttgatact tcgtataaac ttgcgaggtt ttttcaggtc ctacttgatc aaagaacttt
    52261 tgcggttctt ttttgtacca ataatcaaaa atgttctctc cttttccatc gcctgaaatc
    52321 cttccttctg tttgtgggcc acttgctgca gaaccccacc aaaaatttgc tggaaattga
    52381 tattttttca tcaaagcacc tctttttctt ttttagttcg ttttagttga ttccatgtat
    52441 gatattttcc atcacaatca ctttttcatt ttcttcctct tcttttttga ttcgttttaa
    52501 cagctgttct gctgctcgtt ccccgatttt atctgttggt ggcgtgatcg tgattttcgg
    52561 aaggatactc agatcgtttt tatctaaata atcatagtga ctgaacgcaa tatccttccc
    52621 gattctgaca ccttcttgat tgaaacattc gatggcacca atcgacatat tgtaattgct
    52681 gacaaaaata gcagttgccc ctttttctaa taatgctttt gccccgtaat agccgctttt
    52741 tctagaatag tctcctgtaa agacctctaa ttggatcgat ggatcatttt ggaccgcttc
    52801 tttggctcct gctaaacgtt ctcttgctac gtagtctgtt tgagtggcag caataaatcc
    52861 gattttttta tgtccttgtt caccatgatg agcgatcact tttgctacac tttctcgatc
    52921 attcactaat attgtatcaa tacctgctgg tccttctgga caattcaatg cgataactgg
    52981 aatactcatt tttgtgagca tttcaaatcc agaccactct tcttcggata agaagacaat
    53041 cagcccatcg atcacatgct tcatcaggta ttcaattttt tgttcaattt tttctggctg
    53101 atcggcaaac ccgcttaata ataagctata cccattttct tcagctactc tttcgatccc
    53161 tgagacaact tccgacccaa aacggctgga aatcccgttt atcaaaagtc caatagagaa
    53221 gcttcgatta ttcttcaacc ctttagcaat gatgttttct ttatagtcca acgctgaaat
    53281 cgcttctgct atttttttca tgttcttttc cttcagttgc tgaccattca agtaacggga
    53341 aactgttccc actgaaacac cagccatctt agccacatca cggatcgatg ccatacattc
    53401 tcactcctgc cagttacatt tgatttctct ttcttgttgt tcgattatga tgaccgcatt
    53461 ctttgcatag tgttgcttgt catcaatatc catataacta aagtcttcag tagagcaact
    53521 tcctctcact attaattata cttaaacaag tatttgaacc ggttcatttt taatatagca
    53581 tttttttaaa agattgcaac acttttttaa aacgctttct gaaagtggcg gattttttgc
    53641 ctttttaaaa ttttattcta aaatttactc tatttgtggg tgttttgtgc gtttttctct
    53701 tccatccgtt tgaagtttta cattccaatg gtataatttc tttatcctat caaatggggg
    53761 aagtattttg aagaaattaa tcgtactatt tattttgtct gcgggacttt tgacattgac
    53821 tggctgtgat ttgtttggcg gctctgacca atcctcggac gaaacaaccg attcttctgt
    53881 cttaaaagcg gaaaaagcag ataccaccaa cagtgtatat acgctaaaag tacgtaaaga
    53941 tatggattta tccgcgggac agttgacatt tacagataaa aaaatggaat ggacacgcac
    54001 gtatcagaca caaggaactg attcttctga atcatctgaa gaaaaaacag tgctgacaga
    54061 tatcaagatc actaccaaag atgacgaata tattatttca ggaaaagaaa ataaaaaaga
    54121 aacaacagtc atatttacaa aaatcggtaa ttaccgtttg aaggatgagg atggcaacat
    54181 ctacagtcta tagtgccgtc tgttggatct tcttttgttt ctccccttct tttctgctat
    54241 agtaaagaag caagatgatt gtaaaggaga cgaaatggat gatcgatagt cctgattatt
    54301 gtacatgtaa taacaacaaa aatatccata cagaatttaa tgaccaagga agcttgagca
    54361 tatgcgacaa ctgtcacaaa ctagtcaaag attcatttaa aacatttgaa tcttatcctg
    54421 ttcaaaatta tgtaaaaagt agaagaagat aaacaaatcc aagcaaaact cactatggct
    54481 gatttttatg aacttcaaac tcagcttctt cctttgatca agcttcatca gtaaaacaaa
    54541 cagtggatca tttcagttta caaatcaaag agtaaagatt tatttatttc aaatatttga
    54601 atataaaata accaaacgat agaaaggctt attctacatc acgtagtaat ttttctttcc
    54661 cgtcgtttgg ttttttattt ttagcctaat tcttgacctt ttgcatgctg gttatccgta
    54721 aaatattttc cagcaggctt tccttccaat tcagctaatt tttcttggat ctgacggatc
    54781 accttttttg catcttctgg attttctaca aaatcgaatt tatccccatc cacttgtatt
    54841 ttaggacata catcaaaatc ttcataccat tgattatagc gggtgttcaa cgtttcataa
    54901 taggtatata acgtctcatc gctttctagc tgttcatagt cacgcccacg ttttttgata
    54961 cgttctagca tcgtgtccaa agaaactttg atatggacca tcaaatcagg ccgttttttt
    55021 ggagcaacat catctaactc gtttagcatc gtatctaata agctatcgta ctgctgtact
    55081 tcgatatccg ttacccgacc taaatcagcg tttagatgga acaacaggct atcttcatag
    55141 atggatcggt ctagcacatt gtcatcgttc actaaagcat ttttcattgc taaaaatcgc
    55201 ttgttcaaaa agaagatttg caataaaaaa gcgtactgct caggatttga ataaaagagc
    55261 ggcaatactt cgttatcttc gacattttca taaaatggtt tagaatcaat ctcttttgca
    55321 agcatatccg tcaaactgct cttacctgca ccaatcgttc ctgaaatcaa aatcactgac
    55381 atacaaccct tcctcttcta taagtactcg cctacgtaag tttcaacagg caatgtttca
    55441 aaatcatatt cacgtacagc ttggtctgat tttaaatacg tatggagact ttgtgtaatc
    55501 atcaagttcg taggtaccgt ctcttcttgt acaatgatca tcggtttttt caacatagtt
    55561 gccacaccta attcgtaagc cgttcctgga tcgattgttt gatgctcaaa gtcaaggata
    55621 gcaacaacaa attctgcatt tgtcagttct tccatatctt tttcgtatac ttcctgcgcc
    55681 catccagcgc tgaatagttc ataattgctt tcttggtgat gacgtggaga gtagaaactt
    55741 gtgactgttt tgttttcctc caacgctttt tcgatacgac ttactcgatc gatttgctcc
    55801 tctgaaaaaa atggtcctgc taaatatatt tgactcatta ttttgcctcc ttcaataata
    55861 actgattttt aatagatact gctcgtaatt cattgaccag ttccaatgga ttgttggaaa
    55921 agattacttg atccaaccat tttttatcca taaaatcctc ttttgcaaaa gtttctaata
    55981 attgttgcaa gccgctgtaa taaccgccaa tattcaatat tccgattggc ttgtcgggcg
    56041 tcagaccgat tgctatccaa gaaagaagtt gtgagaattc ctccaatgta cctagacctc
    56101 cagggaaaac gaggacagca tctccctttt caaataataa tacctttctt tcatcgatcg
    56161 tttctgtagg aataaatgta gtaacatctt ttccaggcaa ttcagtttca aaaagcccat
    56221 tcggatagat acctgtgact tttccgttat tttccagtac tgttttacta atcactccca
    56281 taatcccgga gtatgaacca ccgtaaacca gttcgatttc ttcttgtgcc atgtattttc
    56341 ctaacgtttg cgcaataaat ttgtaacttt ctttattacc aaaacgggaa ccgcaaaaaa
    56401 cagtaagttt cataaaaaaa cactccctaa ctcaaaagtc tatcttcatt ctacacgtgt
    56461 ttttttaaaa taaaagacta gattttgtag ttttttagtg gtatatagga tagacgccac
    56521 tatatatagt atttagaaaa aaatcatttt tcagccattt tatagataaa acaaaaataa
    56581 ataacgtgtt ttcatcgata tgaaatgact tacttataga agatactggg atttcgtcct
    56641 atatgccaat aacgtgtatt attttaaaca acaaatactt gtttctttta ttaacgaaaa
    56701 aatcattttg ttctcgtgtt atgtttcact gataaatgat gtttctctaa ataaaaaagc
    56761 cgacgaacta aacgatcaaa atttgatcat ttttgttcat cagcttctcc taaaaatctt
    56821 tttgttaacg ataaatagct ggatttgtaa aaatatcact tgaatcgtca ctgctggaag
    56881 aaaattcagt gataaccgca cctgttgcgc ctgcctggaa ctagtgtttg atattgggct
    56941 cgaacgtgta ctgatctcta gcatgaagaa taatttcttt ttttactgta taataacttt
    57001 ctttcctttt tggaatagta caggaaagtt tttttgtttc ctttccttcg acataaggta
    57061 taccagaccc tttcgacaac gaaaggttct catttttcct tcatcgtcat ttcaaggagg
    57121 gtgccgatgc tctggacagt ttcgatcgct cctaaaccaa aatctgtata ttcgattctt
    57181 tctaactctg attctttcat accattcctg tctcaaggta catctattgt acttttttct
    57241 tgtaatccat tctgcctctc ctaactaatt gtcaaatcat cccaagatat gtcttcttcc
    57301 tctttttctt cttggatgat ttctgcattc ggatctactg gttttttcaa taataaaatg
    57361 gttattcctg tgacaaaaga accagctaac aatgcaccaa tgaatgccca tggtctggtc
    57421 atcgtagcga ctgcaaacat tcccgatgcc ggaatacggc tatctgcgcc ccaaaacatg
    57481 cttaatccgc cacctactgt cccaccgact cccgttgcta tgacattgcg tgccaagtcg
    57541 ttcaatacga tagggaaaca tccctctgtg atctgacaga tccccatagg aaaagcggtc
    57601 ttcaatgtat cgatttcttg acgattgagt atatttttac gaatgatttt ccctaagaaa
    57661 taagcgatcg tcaagccgaa tggggttacc atcgaagcta aaatcaatac agtgattggt
    57721 tcatagattc cttctgaaaa tcgtgccaca cccccttatc cagaataaat ggtaatccag
    57781 aaacagccgt gtatctgcgg taataagcct aaccaaacga aaaatatgag aagctatttt
    57841 tgtttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct ttttttattt
    57901 atgtttcata atcaatatgg taaggatgca gctccgtatg gtagaccgcc tccgaatatt
    57961 caatcatttc cccaatttgc gtagacgatt tccgtatccg tttgatgccg atctgtgcgt
    58021 ctgttttcag aattccttgt tcttcttctg ttaaaaatac tgccgagaaa tcatcagaaa
    58081 atgagtcaat agtatatcct tttttcgtca gcaaacgata caaagattct ttgccaaatt
    58141 cttctctgct gaattgcatc atttcttgtg gaagataatg aacaaaataa atataaggct
    58201 gattgttcaa ataatataag cgcttaaaac aaacagcttg ctcaccgaaa aaggaaaaca
    58261 aaggatcttc cttctttata tggaccaatt gcaaatccag cgtttctttc cggacttcat
    58321 atcgggagtt ctccaagatt tgcgtaaagc ttgccgcttt ggataatcga ttgtaaggac
    58381 gattgcttag aaccgtcgtc ccacgaccac ttttctttgc gacatattca tctgatgcca
    58441 gcagttcgat tgcctttcgg acagtgattt tgctgacttg aaacagttct tctaattcac
    58501 tttctgtcgg caacatcgaa ccgactggat attttcctga gaaaatatct tctttaattt
    58561 tatctgcgac ttccaagtat agtacacgtg tccttttcat aacgtcaccc tttgctttac
    58621 tattactaaa agaatagcac ataaaaaata aaaaaagaac acaaatcaca tgtgagaagt
    58681 gtgttctttt tcattcagct gctttaatta caagtttacg ccatttgagg caattacttc
    58741 tttataccaa tcaaaagatt ttttctttga tcgattcagt gtcccatttc cttcatcgtc
    58801 tagatccaca tagataaagc cgtaacgttt actcatttct cctgttgatg cactgacaag
    58861 atcgatacat ccccaaggcg tatagcccat caaatctaca ccgtctgcta ctgcattagc
    58921 catcgcttcg atatgacgac gtaaataatc gatccgataa tcatcaataa tcgtgccatc
    58981 ctcttccata tgatcaatgg ctccaagacc gttttcaaca atgaataatg gtttctggta
    59041 acgattgtat aattcattca atgcgattct cagcccttct ggatcgatct gccagcccca
    59101 ttcacttgcc tcaagaaacg gattttttac tcctcccagc aagttccctt ctgaagttgc
    59161 tgcttgtgga tcagtctcat tgattgccgt agacatataa taactaaatc cgatgtagtc
    59221 cactggatat tcttttagca actggaagtc tttttccgtt tgctctaatt tttccggatc
    59281 gactccatat tttttatggg tacgcgctgt gtatgcaggg tattctccac gtacttggac
    59341 atccgtgcag aaaaaattga attcttggtt ttggatcatt gttgctgcct gattgactgg
    59401 attggcatcg atgctgtaag ttgttgcata gataatcatg cagccgattt ggatatccga
    59461 acgcaattcg tggccgattt ttacggcttt gctacttgca acgaattgat tatgccatgc
    59521 ttggaaaata ttttggtact ctcctgctcc attgcttttt actaatcctt gacttaaagc
    59581 tggaaagtga aaggccgaat tgatttcatt gaaagtcatc caatatttga ctttactgct
    59641 gtatctctct aatactgtct gagcaaatcg ttcatagaag tcgatcagtt ttcgattttt
    59701 ccagccaccg tattcttttg ccaaatgaag aggcatttcg taatgagaaa tcgtgatcac
    59761 aggttcaata tcatatttta agcactcatc aatcagctga tcataaaatt ctaatcccgc
    59821 ttcgttagga gtaccttcgt ctccatttgg aaaaattcgt gtccaggcaa tcgaaaaacg
    59881 ataacatttg aatcccattt ccgcaaacaa ggcaagatct tctttgaaac gatcgtaatg
    59941 atcgattcct cgatgattcg ggtaaatata tttttcttga tcaatcgtcc agtcaaattc
    60001 ttcactgccg ataatcgcaa agcgctgctt acctccaggc atagcatctg caacggatag
    60061 tccttttccg tctcgatcat aagccccttc taattgattt ggcagcagtt gctccacccc
    60121 ataaaaattt ttctgaaaaa cgtgattgca tcctgatttc ctccttattt tacaattgcc
    60181 agaacatctt cgtttgcaat aatctctttt tggtctaatt caagtatatc ggcaaatgca
    60241 tcagtattcg taatgacaac tggagtgatt acgctatagc cagctgctct aattgcttcg
    60301 atgtcaaaac gaatcaataa atctcctgct ttgacgagat ccccttgttt gactaagatc
    60361 tcaaagccat tcccatttaa ttctactgta tccatcccga tatgaatcaa aatctccgct
    60421 ccgtcagtcg ttgtgatccc tacagcatgt ccagttggaa aaatagtcgt gatctctccg
    60481 tctgcaggtg caactagttc tcctacttct ggatcaatag cgataccttt tcccatcacg
    60541 ccagaagaaa aaacttggtc tggtacttca ctcaatggca gtactttacc cgttaaagga
    60601 ctttttaagg tatgccgtgc tgaagtaatc ggttctcctg cattcgcatg tttgttttct
    60661 aattgattgt cttgtgtttg ttcgtcaaat cctaaaatca atgtacctac gaatgcaaga
    60721 acaaaagcaa ttcctgtagc tattactgct actgtcacat ttgactctac accatccacc
    60781 gtattaatga aagtcggaat cgtcaataag ctgaccaaac tgctggagaa agcttttact
    60841 ccggaaaatc cgataatagc tccaccaata cctccagaaa tacaagcggc aatgaatggt
    60901 ttcttcaaag gtaatgtcac accatacaca gttggttcag tgattccaaa taacgaagtc
    60961 actgtagaag aaatccctaa tgctcgaagt ttcgtatctt ttgttcgcaa tgctacagct
    61021 aaagcagccc caccttgtgc caagatggct ggaagaagca ttggcatcaa tacatcaaac
    61081 ccatattgtt cgatattcaa aaacatgatc ggtacgaatc cccaatgcat gccgaacatc
    61141 acgaatactt gccataaact tcccatgatt agacctgcta cgattggact aaatccataa
    61201 atcgagttga agagaccgcc taaagcatta ccggcaaccg tcccgattgg tcctaaagca
    61261 agaaatgtta atggaaccat cactactaaa acgacaagcg gaactaaaat catttgcaga
    61321 aattgcggaa tcactttttt tacgaatggc tctaatttac tttgaaccca tacggctaga
    61381 atgattggta tgacagaaga agtataacca gatggtgaaa gaatcactgg gatcccaaag
    61441 aaactgatag cttctcccgc accagcaact gctgtgatag ctggatacac aagtgccata
    61501 gcaattgcta ctgctaaaaa ctggttggct ttgaactttt tagctgctgt aaaagcaagc
    61561 atgacaggta agaaggtaaa gacaccatct gctgcagcaa acaatatttg ataagtaccg
    61621 ctatcagctg tcagccagcc catcaccgtt gccaatgata agaatccttt caataccccg
    61681 gcggctgcca tcgcccctag aaaaggtgta aatatactag agataatatc gatcagacga
    61741 ttcaaaatat ttttggactc ttcttttcca tcctccgaaa ctgcaagacc ttcctcatcc
    61801 acgatcgatt gataaacatc tgctacatta ctgccaatca ctacttgata ctgaccgcca
    61861 ctttgtacga cttggatcac gtccgggtct tcttttaact tttgcgtatc tgctaaagat
    61921 tcatctttta atctgaatcg caaccgcgta gcacaatgta ctaaactttt gacattcttt
    61981 tgtcctccta ccgcttccca tacacgacga ccaactgctt gattatccat tgttttttcc
    62041 ttctttcttt tttatttaaa aaataaaaac ccagattgaa aaaaacagtc acaaacattc
    62101 gtgaacctat tttttcaatc caggttttgc ctgccataca gtaacaatcc ttatgattgg
    62161 atgctttttt tctcacttac tactctttga atatgaatcg ttaaataaat ctgctctgcg
    62221 atccccattt cctgtttttg cgtttgtcga agatactcat tgatccgttc gacacaatga
    62281 aacgcttttg gatactttcc ttgaactaat gcgtagagaa attcatcttg ctcgtcagat
    62341 ccttcccctt tgagataacg ctgggcaaaa aactgcagat gagtaatgat acgctgataa
    62401 ttcaaagatt cttcatcgaa cacgatgccg aagaatttac tgatgatact cagtatatct
    62461 cttaccattg tggtagcggt catcgtcact tgcatgtctt cgtttccttg ttggctattc
    62521 acaaaatgaa aggcaataaa accggcttca tcctcagaaa gttccacacc cgtcttttgt
    62581 ttcacgaaca aaagagcctc tttcgctgct tgatattctt tcggataaaa tttttttgtt
    62641 tcaaataata atggattagg cagttggata ttttcttttg ctcgtgtgat cgcataatga
    62701 agatgatcgg tcaatgtcag ataaatatta ggcgaaaatt caacttttag tttatcttca
    62761 gccagttcga ctacttgttt gacccattcg atctcctctg ccggaatatc agccatcagc
    62821 tgctggaatt ggtttttagc aaaagaatct cttaaacaaa ttctttttgg accgcttctg
    62881 gcgaaatctc gtccccaatc tttttttgaa aagctagtcc ttttcccata caaacgactt
    62941 cttccccgaa tccatttttc gaaatgacga cattgttatt caaaatttta tcaattttca
    63001 ttttgcttcg ccctctcaag aaaaataaaa aaacctagaa ttcgcctact gtttcttagc
    63061 tgaattctgg ttttgcctgc cgtacagtaa caatccattt cttattcaaa atcatcatac
    63121 catcgaattt ttatttatgc aagccttttc atataaaaaa taaaaaaact ggaacacaag
    63181 tctatctaga aaacaaccaa atcagagatg cacctctttg cgtttctctt tttttcagca
    63241 aattggtttt tccttatcga ttcatatcct ttggctgttt ttaatctgta acgacttatg
    63301 tcccagtatc ctaaaatgtt tttgtctcta gattgaaagc agatctcata tcatctgtcg
    63361 catcttttat cgatgtaaca ctttccagtt ctccttgtac aactagtcgc gtgacggcgt
    63421 ccatgtcgcc acaagtaatt agtgtgacaa tttcttttcc ctcgacttca ttcagtaatt
    63481 gggtatctgt aggagcaact ttttctttaa aaaatgtttt gtatgtatac acattttcta
    63541 aatctgtcaa atagatcttg gcacccatct ctaaattttc tagcggtgta aacagcaatt
    63601 cagggttcgt tgcacgatgg cttgctaagg cataatttcc ttttcccatt tcttgatctg
    63661 gagataatgt tcctgctccg taaagtagtg acgtattatc caagcctttg aaaaccggta
    63721 aattgattga aactgaaggg actgcgatac tagcaatcac tggtagatct gttcctctca
    63781 tttgcgacct catgacccct tctgtcgtca ttggttctac cgcatcaaag tcaaaactga
    63841 catctttatc gttattcttt ttcagatctt cttttgttac attcgctata gcatatttat
    63901 ctcctgtctc tctgacaaaa taatccttga tctgttcatt gaaaatcaaa gctagtccta
    63961 ctaataacaa gaggaacaag aggatattga ctagccatct ttttgctttt cctttttttt
    64021 tcattttctc tccctccaga ctcattttac tgtttttctt ttgctctttc caacagccga
    64081 atgacacatt tctacaactc tgtgtatttt tttcgtacac ctgcgctttt ttctacagga
    64141 tatttcaaat tatttttgat caatttttct tcaatgatct catctagatc caggtgaagg
    64201 ttgtctgcca tcatgtatga atagatcaat acatctgcca gttcttcttt gattcgttct
    64261 aattgtgttt cttttacttc ttccggcgtt ttccattgaa aaagttctaa caattcagat
    64321 gcttccaaag aaatagagat agccaaatct ttttcgttat gaaattgtcg ccaattacgt
    64381 tcatctctaa actggttgac tttttccata ctattcattt gcttgccttc ttccaatcac
    64441 ttcttacttg attaatcata ccattttttt acataaaaaa tagatgatgc ttttaaaaaa
    64501 actcctgttt tcttttattt aaaataaatg tcatagaaaa tcaataattt aggtagccac
    64561 catgtgtatg cagtagcgtg tcttcttccc ttgaggcttt ttgtttttcg atacgttctt
    64621 cttcccaaac agacaacgct actagaatct ctcttaatga ttttccttct tcggtgagcg
    64681 agtactctac tttaggcggg acttggttat aggcttttcg atggatactt tcatcttgtt
    64741 ctaactctct taactgctgg gtcagcattt tttttgtgat cgtagggatt tgcttgcttc
    64801 tccacgccta aaataagcga tattgctctt ccctttatct ggtgtaagca aagcagttag
    64861 cattttgacg atcgtgggtt ccgcttttca cttcttatct acttagtatc atgaagtata
    64921 ctttcgtact aatactaagt agcggaagtg tcaactactt tgtttaacta catagcaaaa
    64981 gaaacagaag ggtgacaacg gtcatcacgc ttctgtttct tttgaatatg ctgtgttgtt
    65041 gtctctatct ccgtgtagac tttcctcaaa cttatccttt gacagtaagt cagtaggctg
    65101 atttgctctt tctagatgcc agatacattt ctacaaaaaa atagtgattc tgttttgaaa
    65161 attcgatttt tagttctgca ttttcgtaaa catccaacat ttttttcgca ctgtatagac
    65221 ctaacccgcc atttttttta gaggtttttc ctcttttgac catctccgat agcgtcaaat
    65281 tcgttggatt tgccttgttc gctatactaa aacgtgatcc ctctttttct tccagcagat
    65341 tgatcgtaat cggactctga tcggctacac gatgatcgaa tgcgttagaa ataaaaatag
    65401 ataaacagcg aataaaaaca accagatcaa tcgggattgt tttcacttcg acaggaataa
    65461 ctacttggat cgggattttc tccgattctg ctttttctag aaattttaaa aagacacccc
    65521 tgacagctgg ggatacaata tttgttagct gttgtatttg cggtttttca aaaatagctg
    65581 cagaatgatc ttctaatatt tctaaaaatt ccaacgtttc ttttttattt tcctgaagag
    65641 taatttttaa tgaaaacagt agacttttat aatcatgttt gaattcctct agatgatggt
    65701 aatattcttc atttatttga tacagttgaa gcgattcctg atgttgtctt tcttttactt
    65761 ggaaactgat caacataatg gaaaaaaaca aagaaaaaaa actgatgact atcgacaaaa
    65821 gagatagaag cagataatta gatgagcgga agtgaacact tcccaatacc aagtaaatca
    65881 cgccccagct taataaaata caaatacctc caaaatagtg ttcagttgga taagtaaaaa
    65941 gcaagttgag aaatctcgtc tgtttgtcta tactttttac taatagatag aaaataaatg
    66001 cgataagtag tgcaaaaaaa cttgctgttc caagatgtct ctttcctaaa taatccatca
    66061 gatcaaaaac cagaaaaaag ctgagtccag tgatagcaaa aaaaagatta ctgatcaaac
    66121 agctgataaa caggtttttc gtagtaaaat aaaaaagaaa catcaataat aagccaacta
    66181 ggtaaggaaa gctcacttta gggataggaa gtaaaagtgt caccaccatc aaagctatac
    66241 aaccaaagct gttttttact agcagttgtt tcgaaaagaa taaatagata cctaaatcta
    66301 aaatcaaagt aaaggtcaaa taaagtgtca ctgttgcgac catcttattc ctccattgtt
    66361 ttgtttcaaa atgtacacat atttttttaa taggagcctg catatgaaaa agtattttat
    66421 catagaagat aaccagtttc acagcgaatg gatcatcaga gaattggtca atcatcatat
    66481 cgagaatatc gtgcagctca cttctatctc tcaaatcaat cagttgatcc agttgggcac
    66541 tattgataat cacgatgttt tctttatcga tatcgacttg aagcaatcac tcacaggtat
    66601 tgatgtcgcc gaacaaatac gtaaaaaaaa tgcacatagt aatattgttt ttttcaccgc
    66661 ttatacgaat tttgcagtag agatcatcaa tcggaaaatc cttccgattg gatatatcag
    66721 aaaagacagg aatttatctg aacaaattcg tcaagtgcta gaacagatca attggaaaga
    66781 acagcagatc gtaaatgtcg ataaaatctt tattgatcaa aaaggtggaa gtctcgtcct
    66841 gtatcctcgg gaaattttat atattgaaag tatcaaaggt ttgaaaaacc aagttatggt
    66901 caaaacaact acagaagata aattagtgaa tacttcttta aaacaattga agacagagtt
    66961 agaaaagtat gcttactttt tacttttaaa atcttactgt atcaacttat cgcaattgca
    67021 gaaaattgat tctgctcatt atgtgttaga atttttcaac ggtgactcct tactcgttgg
    67081 tcgaaagatc tttgaaaaga caaaggaacg tttccatgac ttccaaaaaa ctgcttcgag
    67141 ttgatgaata agagctgaga cgtaagcata gcagatttca gggagtgggc cttgaatcgg
    67201 ctccactccc tgaaatcgtt gatatgattt tacgcttcct cttctgtagg agcatctgtt
    67261 aacgaccatg tgaatgttga aacgtagttg tctacagcat aattggatac aggaacaaat
    67321 aattccactg attgtctccc ttgttccaca ttctctccta atgaataaat ccatgtgcca
    67381 atcccttcat ttgctcctgc agttactaga tctactgcct gatctgctgg gatttcgatt
    67441 ccttcagcgc cagttccaga aacggtagat ggcattccac tgctattagt tgcgctattt
    67501 cgaatcacgg cgtttttgaa tttcaccttt gaaccagtta gtttattcgt atcagatgtt
    67561 gtaccaataa attctgttcg tttgactgat aatttccaac cggcataatt tccgctttta
    67621 tccgttactt gtacgaaatt ctgtacttgt gtttgtgctc cagtactgtc cgttccgctt
    67681 tgtaatgcag catatactgt ttttgctgta cctaacttga ttgttccaaa atcaagatct
    67741 ggagcttggt caatcgtcag taatccggat gttccctgat ttggttcgtc aggtgtaaaa
    67801 ggagtatcag gatcatttgg atcaacagga ggaactggaa caacgtcttc aggatttgca
    67861 gcatctggtt tggtcacaga aatcgttcct tctgtagtgg ctgagctctt attctcagca
    67921 aaaacacttt gtgtacataa taatagactt ccagctagaa cggtacttaa tgcaattgtt
    67981 tttttcattt ctttttcctt ctttctttta aaataaataa tccagcaaat aagccaataa
    68041 gaatgactcc aacaagtatc agccatcgcc agtcaaatgt ttctggctga ttttttaaat
    68101 caatatcctt ttcattcaat tggtccgctg catcatcagt tatttcaaaa tcggtatgga
    68161 gattccagcg tttttctttc caagcaccct tcacaaccgc ttgataatgt cccggagcta
    68221 atttttttcc ttctaatggg acaagtaaat caaaatttgt attgggtgct acatctattt
    68281 tttctttttt tattgaaagg taaggctctt ttgtttcttt tttgtagatt tcaaccgatg
    68341 tagtcaagcc gaacatataa gaagcatttg gattttgaag attcgcctta atcacatttc
    68401 ttccatcgct ttgatccgca taagcttttt ttaatttcaa atctggggaa gactcttttt
    68461 cgctatttca aatcaagatt gctttcactt gagaaaactg attgacgaca ccaactgtac
    68521 ttttgttaga aacgttctct tttttttctt gaaacgtgat ccctcctgcg accacaccag
    68581 ccagctcttt ttctggcgct ttcagtgaaa gtgtctcagt gaccgcactt tgaggaggaa
    68641 cagttatttc tcccactgtt tttgctaagt ttttcatatc ataacttaat gtttcatcaa
    68701 atttactttt tgattctcca tattcgatca caccgtttga attcgtcgta gcggagtgga
    68761 tcaatgtctc aactgttact gatttatctg ttcggttaaa gaccgtgtag gggatttcct
    68821 gtgttttccc aggctccatc cttacattta tatatgtttt gttcttatca atctgattag
    68881 ccggtaattc aaaatctacc gcaaaattga attcggaggc atggacaggt gtctgccaaa
    68941 ggatgaatcc aaggagaagg atcataagta aagagcagtt gtttcgatga cttttattcc
    69001 atattcgatt catcaatcat cctccttgat ctttattctg tcggcgcatc tgctaatgtc
    69061 catgttatct ctgctgagta attaccagct atctgatttt ctttggttaa gacaagttta
    69121 aacgcccgac cgttatttaa atattctgaa taatctgctt gcacattcgt tgaattttgt
    69181 cctctgacaa tttccagttc ttcttcattc actaattgat actcctctcc tttcttgaaa
    69241 tataggacat cctgcataga aaatcctgca tcatttgtga aaggctgaga taattttatc
    69301 gttaagatcc acggattttt cgtttctcgc tgatcataaa tccataattt ttcctgtata
    69361 tccatttggc caaatgcttc ttgtgtcaaa ccagttgctt tgatctgacc aaaatcgagt
    69421 ttggaagggg caagaaatga gagaccacct tctactacga tcttcgtagc aggtgcaaaa
    69481 ggcggggcat catgataaac aactggcgta tcacttggat tgtgattccc aatttcatcg
    69541 ttggtacttg gcttgttctg cacaccctta gcagtagctt ctcctgcttg gtcgtttaat
    69601 acaatttcta atacatctcc tgcaaaaagt tgattttctg ggatagaaag aacaaattcc
    69661 cctgtatcat caatagttgt ttctgacaaa acagcttgat tttttttcaa tgaaaccaag
    69721 gctcctgctt cacctgtacc tgtgatcgtg cgagaagctg cattgatcaa tgtggtactt
    69781 aaattagcag gttcaggagg aatcacatcg actgtcgttt tggcagagtc cagttctgtc
    69841 acttcttggc cacctcttac ttttttagca gcaacaactt gcacttgatc ctccgttttt
    69901 aatctctcat cattgggtac ttgaacttcg aacaagccgc cttgttcgcc ttctccccat
    69961 gggttatatc ctgccccttc attttcatct gtttgtcctt gcgtgagagc agtaatttct
    70021 acagatgatt tcgtcgtatc tgcgtaagta atacgtaaag tcacttctac ttcgcctgtc
    70081 caagcatctc ttggctttgc ctcgacacct tcgggaacaa cgacatgccc atagattttt
    70141 ttatctgcat tcgttggcac tcttaaggat tcaatcatcg ggagctgatt attggcactg
    70201 attcgattat aatttttcat tccggcacct gtctgagcaa attcatttgt taaacctgca
    70261 ctagggcttg atacgaaatt gcctaagtcg gtcccattga tcgataagtc tgtcatatca
    70321 gaaaaataat ccgggtcttt ttcaaagtta tcgaatgttg cgcctgtttt tcgccataaa
    70381 gcgatttctg aatgggcgat ctttaaagaa gaatctccat ttccttggaa tacccagccg
    70441 cctatgccat tggtctcgct tccaatccgt ttgttttgga aatcaaaata ggtaggagat
    70501 tctaagtcca cattcaacac atccccactg atgatgccgg tcttatcttc ccctgttttc
    70561 ccgaccatga ctaaataagt tttttcacct gccgtaaaat ttaaatcaat atctccagtt
    70621 gtatctacag ttgctccgga atctgcgcgt atatcgatat ttgatttttc tccagtgact
    70681 gtaaaatcag ctgaacctgg actttctaga aaaccagaag cgtcataaaa ttggatcgct
    70741 tgatttcctt gattgagtct gttcacgtaa gatttgccat cacctgtatt tcttaccctc
    70801 aatgagcctc cattggttac tgtcagcttt tgcgtaccat tctcaaaacg aactgcgctg
    70861 gaacgcccac tctgcttatc gatgtcgata actgatccgg ctccttctac gatcaaagaa
    70921 aggccttttc ctacaaaacg catcccattg ttcccgggtt gatcgtcatc tccagccatt
    70981 ttgaccgaga tttgtccacc acttgataca tggatttgac tagaatctcc ttgcaagcga
    71041 aatccgcccg tagttgctgt attgatggtg attttcccac cattcgatac agtgactttc
    71101 gatcctgaac ctctcatttg gatgattccg cgattgttgt cattggtaat attgatcttt
    71161 gtatttaccg aaaattcgct tcccgaacca ctgacttcaa acatgacatt accaggtagc
    71221 gtatcgactg cctctccttc atcgctaacg ccatctgccc gatcataatc aagagagacc
    71281 tttgaaccgc ttaagatatg gattcctggc gctgtttttc cactaccagt ctcatctcct
    71341 gaatctagaa aaccgtagaa tttccctaga tacggtccat aaagttgact accattgatc
    71401 acattcaatt gatagcttct acaaaaatag gctttacccg gagcggcatt cagtccttcc
    71461 ttcactggtt ggacatccaa cacaccggaa acaccatcta atgtgacagt tgcacgagga
    71521 gcgtaaatca gtcctaattt ggacccatca tacaaatcaa gtgtcccggt aaattttatt
    71581 tctcccgtaa aatgatatct gcttccccaa aaatcggtca tataagcaat gataatggca
    71641 tttccatcga tatttggtgt caatccacct ggatgtgcag ctgttccttt aaaattctgg
    71701 aactcgatcg actgaggtat ctcattgata taaatatggt gtgtgccgaa attgtgagcg
    71761 aatccaccaa aatcaataac gatatctcgt ttgatctcta attccctgtc taaagtcaaa
    71821 ggctgaatca gtcggatctt agttactgat tcgtctgcga gaagctgcgc cagttcttct
    71881 gttgtggcag cttcgctgta cccatccgct gaaacagctc ttgccagtgc cgcttcactg
    71941 ctatcagacg tttgttcagc tacttctgag gtctcacttg tcttattttc ttcttgcctt
    72001 ttattagtag aagcctcact ttgagattct gtagtttcag aagtaatcga ttcttctgaa
    72061 aaagtagtct tgtcaaaact ttgattctct gattgcgttg attcgtttgt tttctctaca
    72121 tcggcaaaaa cggatgtcac catcaagaga gggaagacaa acaaaatcga cgcaatcagc
    72181 ttttttacac attgattcat tctccaccat cctctctgac gttttgacaa ttttatttta
    72241 tcgttttaat ctatttccaa ttgtactttc atatttaaaa tatgtatttt tatggaaaaa
    72301 tttttctatt aggtgtaaat ttcttttttg tacaaaaaaa aggctgtgac aaaagtcttg
    72361 tcacagtccc ttatcccgaa caagcggtgt tctcccgcca actcctcggt cacaacctcc
    72421 attttaacaa taaacctgta aatgtgaggg caatactttg attgtcacag gtaatttatc
    72481 cccttcatct ccatcaacat tcgtcgtcaa ttcttcctca tcagctaatg acacaactaa
    72541 ttgctcacaa gtaaggtagg ctagattttt cgtagattca tctactcctt ttaataggtc
    72601 tggcaatgtt ttaagcgtat cgatcaaaga agaatctttt aaataaacca aatggagctt
    72661 accatcatcc acttttgcat ttggaagtaa tgtttcaaaa ccgccgactg agttagttag
    72721 tcctatcagc aaggtactgc tctcaatttc ttccttcttt ccatcaactt ctacgtgaaa
    72781 cgagtaggat tgtgtggaag ctaactgttt gattcctgac atgaaataag ctagttttcc
    72841 aaatttcgtc ttcttctccg catctacatc attgattgat tcagggatag agccaattgc
    72901 gacgacattc ataaaatagt cgtcatttat ttttccaata tccaatggct tgactgattc
    72961 aatcgaaaaa tgattgatcg cttcctcagg ttctagcggt atccctaatg ctcgagccaa
    73021 gtcattcacc gtacccaatg ggaaaaatcc gaaatttggc cgatgttctt gttcagcgat
    73081 tccactgatt ccttcgttga ctgttccatc tccgcccatg acaaacacac tatgataccc
    73141 ttccgtagcc gcttcgcgag taaagttttt tgcatcccct gctttttttg tatgcaagac
    73201 gaccacttca tcaaacaccg attccaattt tgctatcgct aattgctcaa attcctttgc
    73261 ttgttcaccg cctgaactgg ggtttaccac taataaaact tttttcatca ctttctttcc
    73321 cttctgattg atttctttaa tataacgata gcataaagaa aaaaattagg ctgtgatgaa
    73381 gtactgttca tgaaacattc atttattttt tgacaagata aaacatccat actatgaaac
    73441 tgaggaaaat taaaacaatg atataggaaa taaaagaaaa tgataggcat tgtataccta
    73501 ataaagtaaa aatcttaggt ggcagataaa aacacaaaaa tagcaagaga atgtaatagc
    73561 gtttcttcca ctttttgtta tcagacctta tagcgatcag aggaatacca aatgcataac
    73621 tgaaaaactc ttgatgtact gttaatatgt cacggccttg aataataaat gcgacaatcc
    73681 ccgctataat tagtgtgcct aacaccaaaa cggaaaattg atgaatatat tttatataca
    73741 aatgatccat tgtacttcct gcctttttat ttgtgagaaa aacaaatccg tatacgtgaa
    73801 taacttctag aaataaaaga aatttgcaaa accactccat ttatctactt ctacgtgcat
    73861 tttttgatat tgttttcttt atttaagatt atacagaaaa atatctaggg tcgctggatt
    73921 ctaagtaaaa aaaattttta aaataaaaag aactaaatca agtagtaatt aaactactgt
    73981 tgatttagtt ctaataaaaa gatttagatg aacagtttta ttgatttaaa tagttcatat
    74041 tttttattta taccgcttat ttactacttg ctgtactaga atctgaagtg aatgtactca
    74101 aaacattttc aaagtctttg tctttgattt ttacattagc gtctttcaat acttcgccaa
    74161 ttactttatt ctggaaggta ctgtcactta attttgtgtc tgttgcaatt tctttcaatt
    74221 cttttttgta tttatccatg tcgttgcctt tgttttggtt tttcaccatt ttaaccacat
    74281 aatattccgt agtataagtt gaagcattgg tagaagtgat cacatcagaa acttgaccat
    74341 ctttcaactt aaaggctgct tctttgactt ctgccggaac cgttgtagta gtggaatcaa
    74401 atttcacttt tccgccatct tcttttgtcg tagtatcagt tgacttgtct ttggctaatt
    74461 tagagaaatc gtctccctta tcagcagctt tcttcacatc ttttgcatca tcttcacttg
    74521 ctacttggat aatttgagct tccacttctg gatggaaaga ttcccaagcc gtttttaaat
    74581 cttcatcggt caatttgata tgtttcttta gaccttcttg aaaggctaga ctttgtttga
    74641 tactgtcttt gaatgtttgt tctgtgtaac ctgcagattt caattgtgaa tcaaatgaat
    74701 cacccaattg tttctttgtt tgatcatatt gagaatcgat ttctttggtt gatacgtcat
    74761 ctccatattt atcttcaaat acttgataaa cgatcaactg ttgcacagcg gaatctgctc
    74821 cttgcatttt tttcaagcta tccattactt cttgttcgct gattgtaccg cctttataac
    74881 taacggctgt tttttcaccg gcattcgtac agcctgacaa taagccagtg cctagtacga
    74941 tggcaagtgc taaaaatctt tttttcattt atcaattctc ctacttttcg ttttttgcga
    75001 attgctaaaa acaaaggtgt tcaagatgaa aatcatcaag aacaccttta ctaatctgct
    75061 cgatacgtcc tgaatagata taaggctaca caatccagaa agttcgctca gcagaataaa
    75121 tgtcaagtag cacatcacac cttaatatac tacttctttt gttaccgttt ttcaagtcta
    75181 tcttgcgttc cgtatttaac gtaactaatt cttagaacaa atgttatcga ttttgttttt
    75241 cttcttccgc tgctgggata ttcaaatcag acacttttat gttcgatttt ccagacattt
    75301 ttttgttgtt tttattatga tatattttta tacaactaaa aatgaatata ttaaaactac
    75361 caaaaataac ttttaacgct gtttcattat atgttttttc tattttatat aaacttttgg
    75421 atacttaata ccaaccggtt ggattgtacc aacatgagaa tgtgtcagtt ctatttcctg
    75481 tcgcacttgc ataggcccat actccttttg ttgcatttgc tgatcgaata gagtttccaa
    75541 ctttcgcttt tgcaccgtga cgattataga cacgactata gtggttagaa tgacctgttt
    75601 ttctcgtaca agttgtatca ctataataaa cccatcttcc agagctatga ttaattgctg
    75661 ttctagaaat ttcccggtct actggtaaat ttgacttaat aatattacct ttagcatcaa
    75721 aatgaatctc tcctggcttt aaagatttgt aatagatttc accgtgaact gaatttgctt
    75781 ccacttcaga tgacatagcg tttcctccaa caaaacctat ccctagtgca caaataataa
    75841 ctgctttttt cataaaacga catcctttcc tttttgattt ttaaagcatg atcttcttgt
    75901 ttcctatttt ggtcagatat ggatcatgcg tgactacgat aactaacgta ccttgggaag
    75961 cttgttgcga taagatttca actactttat ccttatttct tttatccaat gacccagtcg
    76021 gttcatcggc taaaatgatt ttgctattct tcaataagac tctcgcacag gcgattcttt
    76081 gcttctcacc accagataat gtgtagatag gcgtacttag cttcttgttt atatttactt
    76141 ttttcaatgc ctcatacttt gctgttcgct tatctgaaac atttaaattc gaaaacttca
    76201 atccaatatc taaattaaaa tcgattgttt catattcaat caacccaaaa tcttgaaaaa
    76261 gaaaagatat ggtatttctt tttatcaagc gcttctctct cccagttaat tgtttcgtct
    76321 cttgatcgaa caaatagaat tgtcctgaac tgaactgatc attcaatcct aatatattca
    76381 ataacgtact tttacctgct ccactttctc caacaacagt cacaagatcc ccagcatccg
    76441 cagtgaaacg atccaaatga agaatcgttt tgtttcgaat gatttttttc gcacctttta
    76501 tcactatcaa cggctccaat tgttaacctc cattcatcag caataactga cttttctttt
    76561 ctgtagacaa aataaaaaca actgaaagaa taaaatcaat gaagctaaag aaaaaaatat
    76621 taaaaagata tttaggctct ctttctataa gaaaaaggaa gattacactt gtcgttcccc
    76681 atttgatgag gttcatcatg aagaaatctt tatacgtttc aaagagcgaa taaccacttg
    76741 aacgaaagat agcgattttc cgacaattgt agacaaaata tatgcataac atgacatagc
    76801 tcaacaagaa gaaagaaaag aaagtgagta aaaatatctg tatcaagtaa tgaaatgatc
    76861 tgcttaacac tttgacagct atctcttcag tctgagtata cggaaatgat aactgcaagt
    76921 tatcacgtaa ctgactttct tcaatcagct caaataacct ttctttcgac aaagagccta
    76981 tcttgatctt taacggtgga tagatttctc cgctgagaat atttctttcc aaatacatac
    77041 tgtttttcaa tgtcagtatt tcaacaaccg gataatgttc gatccagggg atagaaggaa
    77101 taaatgtata aatgggttga ttgtttttta taaatagaaa tttcggttct ttttcactga
    77161 tttcttgata atattctgtt atttgcgcca ggtcattttt taaatctgta tgtctatatc
    77221 gttcagggat caatataaca gggtgcgttt ctttttcggt tatttggatc aaccttccag
    77281 agacatcaat caaaggaaat ttcttaagat aattcagatt tatttttatc cctctgccaa
    77341 actgttcatt ttcttcattc aagtaatctg atacattgac taatatactt ccgtttttat
    77401 tcaaagtttc atataattcc tgatctgctg ctgatgcaaa acgattggaa taaataaaat
    77461 ccacgtggtt tttcccgatg gttactggat aaaatacatg atagtcctca ccagcgattt
    77521 cttttggtgg ttcatgggaa acagctaact gtgaagaaga aaaaacgata gttgctaatt
    77581 cgacattggc aacggtcaaa agaagagaaa acaacaatcc aaatgtaaaa agaatgtatt
    77641 ggatatagtt gaacgcttct cttaacgaag cgattttttc aactaataaa agagaaatca
    77701 aagagatacc atatattccg ctgaacaaga aaacgtacat ctggaacaaa taaagaaatt
    77761 gctccttata atacataaaa ataaaaccac caatgattcc tgcaattatg aatgtaataa
    77821 tgattttctt tttccccaat aaacaccaca atacttgatg taatgaaaag tcattattca
    77881 acaataaact gatttcttta ttcatcaata agaaaaagga tgataacaaa aggaataaaa
    77941 gaatcaatcc aatagttaaa tacactcgat aattatatac gtctgtattt gaaataaccg
    78001 aatacgaata gctattttca aagtcttcaa aaatattagt ggcataatca gtgtgaaatg
    78061 cttgattgaa tcgatcagtg aatagtgaaa tgaaccgttc ataggcttct ttttctctcg
    78121 tcatcaagaa aaattcacct tcaaaatctt ttattttgat cgattcttca atggacgtta
    78181 cgcgaaagga ggtattagaa tagggtacct tctcgtgaga agatttgaca tccccttgat
    78241 aatacaatgt catttcaagc tttggctgta tcttgaagtt ccaagatgta tctacttcat
    78301 tggattcatt tactgttttt ttcatataag aaagctcagt ttctgatgag acattttcaa
    78361 ataccatgat tagctgctca tattcttctt gcccaataaa atgttgtggc aatcgaatcg
    78421 gagtataagt atctgtttga tggaaaaatt catttgtccg atagagtacc tgtttattta
    78481 tactaaccaa ggcaaaacca ctcatgatac cggtcactat gattgtgagt aaaactgtga
    78541 actttttttt gattatcacc actctccctt acttaaatga ttctttgata aaatcatacc
    78601 gtttttcatc aaaaaaacgt atctatcaag tgtataggtc atgtagaata aatctatata
    78661 ctgtagaatc gaaaggagaa gaagatgaac accggagaaa aaatacgaac ttaccgcaga
    78721 aattgtaagc ttacgcaaaa agaattaggc gaaaaaattg gtgtttccga taaaacgatt
    78781 tctagttggg aaaattctcg tacaatgcca gaccttgaaa tgctgtcact tttacatcat
    78841 actttaggtc tgccgattga ttttccttct attgaatcag ctaccgaatc aatagaacca
    78901 acattgccag atgaacctct tgttaacaag aaatcttatt catcaaaaca acccttctca
    78961 ctcaaaaaga cactatcttt ctttctgctc gtcttttgtt tggtctatct ttttcttatc
    79021 aattatcaat acaaaaatga aacgatcgat cgattcaatc cttttttgaa accacaaatc
    79081 ggctatacca cactccctgt aggatacgtg gacaattcca tcgaacgttg ggtatgtaat
    79141 gatatctttg gccatggtac atggctgtct tttcacgctg gagaggtaga aaaagagaaa
    79201 aaccatgctg taatcaaaca caaaggaaaa cacgtcatga acgttcgcct gctcacttgg
    79261 gaagccattc cctcagatta ccaagaaatc ctcagccaag actatgacga cgccttaaaa
    79321 agaagccctc aggagccaga taggcattaa gtaggagatg aacgtagaga tagaaaaaat
    79381 caatgcacat gatcttatcc aaaaaacagg ggtacaaatt aattgaaaaa gccttgagat
    79441 gaaagttcct aaataaaaaa gttcagaatg ataggtattt ctggcttata gtataatatt
    79501 tacgccacag cctcccaatg attctttttg gaatcataat caaggatgga cattcacaaa
    79561 aatattttgc tcattcgatc cgaatagatt aacgaccaat ctagtaagta atatagattg
    79621 gtacgtagtc aagctgcaca taatttagat caattttagt tcttttttat atttctatga
    79681 tctgctcatt tacttttata tgatggctta cagtaacata aataaatatg ataatcgctg
    79741 gtagtttatc caagagtact caataaaata caaaatggat tgttcaagcg cctatcataa
    79801 tgataaaatg aaacaaataa acgatacaag gaggaagaga ctttgagtaa tggcagaaca
    79861 attttttcat tgtaaaaatt gttcagttgt taatctatgg gatttcggta gcatgggcat
    79921 ttttttatag aggaatcaca ccaacctggc cgttttatct cttgttagtg ggaatattag
    79981 taggaaattt tgcccctctt cactatcgta cgaacttttt tccaactgat tctggccttt
    80041 ttcttaaaac aaagacgcga aaattagaaa acattattga aatgacaatt acctgtataa
    80101 tcattttctt agttatattc ctaaacgtct tctaataaga atctcttaaa attagcttgt
    80161 tacagttagt tacctagttt atataacaca gttatcttat cttccttatc aacatctttt
    80221 gccaactctt tgtcttaaat tcgaaacata taagcagagc tacgaacacc aagactgttt
    80281 cggctctgtt ttttgcatca aattcactct tatatagctg ataatctcgg ctctttaaaa
    80341 gaaattattt tcgcttcatt ttattataaa aaggctagga accttgatgt tatcaggttc
    80401 ctagccttta tttaagtatt accccacaga cccttccata tagattttta aattacacac
    80461 tagtttaaac taaaacaaac aaggaaacac ttaccattta atcataaaat tagctcatat
    80521 gaatatatta gaatgtaaaa tagactggtc aaaatctggt caaaaaagag gactaataca
    80581 ggtagt
//
LOCUS       DADVXE010000004        79683 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.004, whole genome shotgun sequence.
ACCESSION   DADVXE010000004 DADVXE010000000
VERSION     DADVXE010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 79683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.004"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(154..279)
                     /locus_tag="KB913_000246"
     CDS             complement(154..279)
                     /locus_tag="KB913_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6818638.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(413..1306)
                     /locus_tag="KB913_000247"
     CDS             complement(413..1306)
                     /locus_tag="KB913_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBB6818639.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(1488..2414)
                     /locus_tag="KB913_000248"
     CDS             complement(1488..2414)
                     /locus_tag="KB913_000248"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBB6818640.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(2499..3260)
                     /gene="pflA"
                     /locus_tag="KB913_000249"
     CDS             complement(2499..3260)
                     /gene="pflA"
                     /locus_tag="KB913_000249"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBB6818641.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(3504..5735)
                     /gene="pflB"
                     /locus_tag="KB913_000250"
     CDS             complement(3504..5735)
                     /gene="pflB"
                     /locus_tag="KB913_000250"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBB6818642.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6012..8462)
                     /gene="parC"
                     /locus_tag="KB913_000251"
     CDS             complement(6012..8462)
                     /gene="parC"
                     /locus_tag="KB913_000251"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBB6818643.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(8474..10519)
                     /gene="parE"
                     /locus_tag="KB913_000252"
     CDS             complement(8474..10519)
                     /gene="parE"
                     /locus_tag="KB913_000252"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBB6818644.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(10685..11119)
                     /locus_tag="KB913_000253"
     CDS             complement(10685..11119)
                     /locus_tag="KB913_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBB6818645.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11246..11884
                     /gene="plsY"
                     /locus_tag="KB913_000254"
     CDS             11246..11884
                     /gene="plsY"
                     /locus_tag="KB913_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBB6818646.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12016..12891)
                     /locus_tag="KB913_000255"
     CDS             complement(12016..12891)
                     /locus_tag="KB913_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBB6818647.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(12973..13764)
                     /gene="codY"
                     /locus_tag="KB913_000256"
     CDS             complement(12973..13764)
                     /gene="codY"
                     /locus_tag="KB913_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBB6818648.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(13782..15182)
                     /gene="hslU"
                     /locus_tag="KB913_000257"
     CDS             complement(13782..15182)
                     /gene="hslU"
                     /locus_tag="KB913_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBB6818649.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15196..15744)
                     /gene="hslV"
                     /locus_tag="KB913_000258"
     CDS             complement(15196..15744)
                     /gene="hslV"
                     /locus_tag="KB913_000258"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBB6818650.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(15781..16686)
                     /gene="xerC"
                     /locus_tag="KB913_000259"
     CDS             complement(15781..16686)
                     /gene="xerC"
                     /locus_tag="KB913_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBB6818651.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(16884..18260)
                     /gene="trmFO"
                     /locus_tag="KB913_000260"
     CDS             complement(16884..18260)
                     /gene="trmFO"
                     /locus_tag="KB913_000260"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBB6818652.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18229..20307)
                     /gene="topA"
                     /locus_tag="KB913_000261"
     CDS             complement(18229..20307)
                     /gene="topA"
                     /locus_tag="KB913_000261"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBB6818653.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(20429..21286)
                     /gene="dprA"
                     /locus_tag="KB913_000262"
     CDS             complement(20429..21286)
                     /gene="dprA"
                     /locus_tag="KB913_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBB6818654.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(21342..22109)
                     /locus_tag="KB913_000263"
     CDS             complement(21342..22109)
                     /locus_tag="KB913_000263"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBB6818655.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22102..22962)
                     /gene="ylqF"
                     /locus_tag="KB913_000264"
     CDS             complement(22102..22962)
                     /gene="ylqF"
                     /locus_tag="KB913_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBB6818656.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            23222..23620
                     /locus_tag="KB913_000265"
     CDS             23222..23620
                     /locus_tag="KB913_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6818657.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            23899..24399
                     /locus_tag="KB913_000266"
     CDS             23899..24399
                     /locus_tag="KB913_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBB6818658.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(24482..25033)
                     /gene="lepB"
                     /locus_tag="KB913_000267"
     CDS             complement(24482..25033)
                     /gene="lepB"
                     /locus_tag="KB913_000267"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6818659.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(25185..25412)
                     /locus_tag="KB913_000268"
     CDS             complement(25185..25412)
                     /locus_tag="KB913_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBB6818660.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(25409..25927)
                     /gene="msrA"
                     /locus_tag="KB913_000269"
     CDS             complement(25409..25927)
                     /gene="msrA"
                     /locus_tag="KB913_000269"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6818661.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(25947..26660)
                     /locus_tag="KB913_000270"
     CDS             complement(25947..26660)
                     /locus_tag="KB913_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBB6818662.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(26663..27559)
                     /locus_tag="KB913_000271"
     CDS             complement(26663..27559)
                     /locus_tag="KB913_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6818663.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(27717..28559)
                     /locus_tag="KB913_000272"
     CDS             complement(27717..28559)
                     /locus_tag="KB913_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6818664.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            28691..29344
                     /locus_tag="KB913_000273"
     CDS             28691..29344
                     /locus_tag="KB913_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBB6818665.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(29407..29934)
                     /locus_tag="KB913_000274"
     CDS             complement(29407..29934)
                     /locus_tag="KB913_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6818666.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(29954..30901)
                     /locus_tag="KB913_000275"
     CDS             complement(29954..30901)
                     /locus_tag="KB913_000275"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBB6818667.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(30913..32799)
                     /locus_tag="KB913_000276"
     CDS             complement(30913..32799)
                     /locus_tag="KB913_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6818668.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(32959..35037)
                     /locus_tag="KB913_000277"
     CDS             complement(32959..35037)
                     /locus_tag="KB913_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBB6818669.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(35050..35325)
                     /locus_tag="KB913_000278"
     CDS             complement(35050..35325)
                     /locus_tag="KB913_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818670.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(35687..36142)
                     /locus_tag="KB913_000279"
     CDS             complement(35687..36142)
                     /locus_tag="KB913_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818671.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(36296..37504)
                     /locus_tag="KB913_000280"
     CDS             complement(36296..37504)
                     /locus_tag="KB913_000280"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBB6818672.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(37616..37948)
                     /locus_tag="KB913_000281"
     CDS             complement(37616..37948)
                     /locus_tag="KB913_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBB6818673.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            38096..38971
                     /locus_tag="KB913_000282"
     CDS             38096..38971
                     /locus_tag="KB913_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6818674.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(39053..39634)
                     /locus_tag="KB913_000283"
     CDS             complement(39053..39634)
                     /locus_tag="KB913_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBB6818675.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(39640..40899)
                     /locus_tag="KB913_000284"
     CDS             complement(39640..40899)
                     /locus_tag="KB913_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBB6818676.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(40901..41947)
                     /locus_tag="KB913_000285"
     CDS             complement(40901..41947)
                     /locus_tag="KB913_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818677.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(42182..42457)
                     /locus_tag="KB913_000286"
     CDS             complement(42182..42457)
                     /locus_tag="KB913_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBB6818678.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(42700..44010)
                     /gene="der"
                     /locus_tag="KB913_000287"
     CDS             complement(42700..44010)
                     /gene="der"
                     /locus_tag="KB913_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBB6818679.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(44192..45421)
                     /gene="rpsA"
                     /locus_tag="KB913_000288"
     CDS             complement(44192..45421)
                     /gene="rpsA"
                     /locus_tag="KB913_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBB6818680.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(45556..46236)
                     /locus_tag="KB913_000289"
     CDS             complement(45556..46236)
                     /locus_tag="KB913_000289"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBB6818681.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(46285..46920)
                     /locus_tag="KB913_000290"
     CDS             complement(46285..46920)
                     /locus_tag="KB913_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6818682.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(46986..48389)
                     /locus_tag="KB913_000291"
     CDS             complement(46986..48389)
                     /locus_tag="KB913_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBB6818683.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(48376..49407)
                     /locus_tag="KB913_000292"
     CDS             complement(48376..49407)
                     /locus_tag="KB913_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6818684.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            49438..49659
                     /locus_tag="KB913_000293"
     CDS             49438..49659
                     /locus_tag="KB913_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBB6818685.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(49824..50561)
                     /locus_tag="KB913_000294"
     CDS             complement(49824..50561)
                     /locus_tag="KB913_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBB6818686.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(50714..52054)
                     /locus_tag="KB913_000295"
     CDS             complement(50714..52054)
                     /locus_tag="KB913_000295"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBB6818687.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(52291..53814)
                     /locus_tag="KB913_000296"
     CDS             complement(52291..53814)
                     /locus_tag="KB913_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBB6818688.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(54192..54803)
                     /locus_tag="KB913_000297"
     CDS             complement(54192..54803)
                     /locus_tag="KB913_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6818689.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(54926..55051)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(55133..55849)
                     /locus_tag="KB913_000298"
     CDS             complement(55133..55849)
                     /locus_tag="KB913_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBB6818690.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(55855..56424)
                     /gene="scpB"
                     /locus_tag="KB913_000299"
     CDS             complement(55855..56424)
                     /gene="scpB"
                     /locus_tag="KB913_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBB6818691.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(56408..57205)
                     /locus_tag="KB913_000300"
     CDS             complement(56408..57205)
                     /locus_tag="KB913_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBB6818692.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(57175..57546)
                     /locus_tag="KB913_000301"
     CDS             complement(57175..57546)
                     /locus_tag="KB913_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBB6818693.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(57565..58452)
                     /gene="xerD"
                     /locus_tag="KB913_000302"
     CDS             complement(57565..58452)
                     /gene="xerD"
                     /locus_tag="KB913_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBB6818694.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(58548..59021)
                     /locus_tag="KB913_000303"
     CDS             complement(58548..59021)
                     /locus_tag="KB913_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6818695.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(59126..59989)
                     /locus_tag="KB913_000304"
     CDS             complement(59126..59989)
                     /locus_tag="KB913_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6818696.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(60185..62284)
                     /locus_tag="KB913_000305"
     CDS             complement(60185..62284)
                     /locus_tag="KB913_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBB6818697.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(62504..63613)
                     /gene="rpoD"
                     /locus_tag="KB913_000306"
     CDS             complement(62504..63613)
                     /gene="rpoD"
                     /locus_tag="KB913_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBB6818698.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(63637..65478)
                     /locus_tag="KB913_000307"
     CDS             complement(63637..65478)
                     /locus_tag="KB913_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBB6818699.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(65660..67975)
                     /locus_tag="KB913_000308"
     CDS             complement(65660..67975)
                     /locus_tag="KB913_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6818700.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(68160..69020)
                     /locus_tag="KB913_000309"
     CDS             complement(68160..69020)
                     /locus_tag="KB913_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBB6818701.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(69079..69600)
                     /locus_tag="KB913_000310"
     CDS             complement(69079..69600)
                     /locus_tag="KB913_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBB6818702.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            69878..70639
                     /locus_tag="KB913_000311"
     CDS             69878..70639
                     /locus_tag="KB913_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6818703.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            70665..73256
                     /gene="mprF"
                     /locus_tag="KB913_000312"
     CDS             70665..73256
                     /gene="mprF"
                     /locus_tag="KB913_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBB6818704.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(73444..74631)
                     /gene="tuf"
                     /locus_tag="KB913_000313"
     CDS             complement(73444..74631)
                     /gene="tuf"
                     /locus_tag="KB913_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBB6818705.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            74999..75355
                     /locus_tag="KB913_000314"
     CDS             74999..75355
                     /locus_tag="KB913_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6818706.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(75596..76600)
                     /locus_tag="KB913_000315"
     CDS             complement(75596..76600)
                     /locus_tag="KB913_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBB6818707.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            76766..77617
                     /locus_tag="KB913_000316"
     CDS             76766..77617
                     /locus_tag="KB913_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6818708.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            77634..77879
                     /locus_tag="KB913_000317"
     CDS             77634..77879
                     /locus_tag="KB913_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818709.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            78066..78770
                     /locus_tag="KB913_000318"
     CDS             78066..78770
                     /locus_tag="KB913_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818710.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            79178..>79683
                     /locus_tag="KB913_000319"
     CDS             79178..>79683
                     /locus_tag="KB913_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6818711.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSM"
BASE COUNT        21994 a        16730 c        13720 g        27239 t
ORIGIN      
        1 aaaagcattt tgaagcctga ctattacgac ttcataaatg cttttttagt tttaaacact
       61 tcaatctaaa agaataaccc aagattggat aaattattaa tgactcgcca ttcgtttctt
      121 agtgattctg gattatcaaa tggacttcct aatctaatca gctagttctt cccataaaat
      181 gccatacttg actgaatcat aatattgatt atttaaaaat ctaacttttc ttatcactac
      241 ttcctttgtc attccacatt tctcaccatt tttttgcatt cctttgtttc cagaccatgt
      301 agtgaatcta ataggtggta gataggcaaa atactcaaat aattctttta accataaagg
      361 aagagaaagg ctcctcctgc aagagtcagt ataatttttg cttactgctc tcttaggttt
      421 tactcactaa aactgttcca tattctttga tataagaaaa tgcatgcggt ataaatttct
      481 tgctcagctc agaaaagatt tgtcgtttaa gaaaggccat ttcctccatt gtcaatgaag
      541 gatccaatgt tggtaattca atctcaaaat tgtttttttc gacaataggt aattctaatg
      601 tgaatgattc ttcttccttt atagtattcg tcacaagtag agactgatgg aaaatactag
      661 gccggcgatt tttatattta ttcttacgta tcctgtcaac gataacttct atttgatcaa
      721 aaaagtacga ttcatttacg tctccaataa gttcggctaa ttctttgaat gccttcgtta
      781 caggaagctg attcttctgt acaaaaaagt aattagccaa agtaagcggg aagtgttcta
      841 tagaggaaag tgtgataaaa cggtacttct catttcctgc agttgtcctc agcaattctg
      901 tctctcggct gtttcttact ccataaaaat acgcttcttt ccgttcatct tcgaaacaat
      961 acgcccaaat aacttctccc atcgctaatt tttgttcatc aacagagagt ctcttcaatt
     1021 gttcagctat ggtttcagca gccgaagtgg cttgttgcaa gtaatcttta ggatcaaata
     1081 ttggaaagtt caaatgatat cttcgttctt ccctcttgat taatcctgca tcgatcaata
     1141 aatcaagaaa atgggaaaat ttattttgcg aaaattcttt tttcaattct cttagaatcg
     1201 tttcttgttc tcgatgttca tatagataat cggtcaatga agaaaaaagc ggatcatcgg
     1261 tcagtttttg ataaaagttt tccttatttt ttgaataata gttcatatat gttctctttt
     1321 ctatccgttt tattttactt aaaaggcttt tacgtaaaaa ggaggaagaa caagagtcat
     1381 aattgactgt tattctcctc catttcttcg gcctttagta tgttctatgt ttctttttat
     1441 atcaatcgct tatccattca ttttgaatgc ttcatactac catttgatta gctaaataca
     1501 gccgtcaatt gaggtacgac ttgtttttta cgtgaaacga cacctttaag caaagcacgg
     1561 ttgttggtca aagttgtttg gaaagcttct tctacttttt cttttccttt accagcaaca
     1621 agtaattctg aatcactgtc taagatgttt gtgacaacta atacgaacag atcgtagcca
     1681 tttgctttca tttcatcttc cattgctgct tctagctctg cttgtcgatc catcacttca
     1741 ttaaggtcca ctgtattgac ttgagcgata cgaacgttgg aactgcccat tgggaaactt
     1801 tttgcatcca aatcaagaag aaccgcagct gatttatcac ttagatttgt tcctgctttc
     1861 aacatttcaa gtccataagt gtttagatcg acttcagcga ttgctgcaag ttcttttgca
     1921 gctgcttcat cttcaggcgt acatgttggt gatttgaaca acaatgtatc tgaaatgata
     1981 gctgagagca tgattcctgc gatttcttta ggaattgtta cttggttttc tttatatagt
     2041 tttaaaataa tcgtacttgt acatccaact ggttctgcac gatagtacaa tggattagct
     2101 gtttcaaagt ttgcaatacg atggtggtct actacagcta aaatatttac ttcgctgata
     2161 tctgaaatac tttgttggaa ttcattatga tccacaagca tgacatctgc attttctgct
     2221 ttagctgact ctactactcg tggtgcagat agctgaaagt ggtctaatgc gtattgtgtt
     2281 tcttcattag gtgtacctag agcaactgct tctgtttctt tacctaattc attttgcaag
     2341 tgtgaaaacg caatggctgc cccgattgca tctgtatctg gattttggtg accaaaaact
     2401 aaaatttttg acatgtcatt cgctcctttg tgatttctcc tatttaataa tagcaaaaaa
     2461 acggaaagaa gcaatactta tcttctttcc gatgcgacct atcgcgttaa atattttgta
     2521 tactcttctg tatgaagcaa tcgtttagca ttttcgacac gttcttttgt aggtggttcg
     2581 atcccttcta atggatattt caaaccaagt gtttcccact tgtattttcc catcgtatga
     2641 taaggaagaa tctctactct gtctacattt gacaaggttt gaataaagtt gtctagtcgg
     2701 atcaaatatt catcataatc acttcgctca ggaactagta catggcgaat ccaaaccggt
     2761 ttgttgattt ttgacaaata ttgagccatt tctaaaatat tttcattgtc ccaatgcgtt
     2821 agttttttat gctcttcatt atcgatgtgt ttgatgtcaa ataacagtaa atctgtatac
     2881 ttcatcaatt cttgaaaacg tgaaaagaaa ggttcttcat acgtaaaagg ttttccgcat
     2941 gtatccaatg tagtatgcat cttccgctct tttgcttttt taaatagttc gatcaaaaaa
     3001 tcgatctgca atagaggttc tccaccacta acagtaatac cacctttatc tccccagtaa
     3061 ggtctgaagc gttctgcttt atctaaaagt tcatctgctg tgtattcttt ccctccgcca
     3121 atattccaag tatctggatt gtgacaaaat tggcaacgca tgcggcatcc ttgcataaac
     3181 acgacaaagc gcagtccagg tccgtctact gaaccgaaag tttcgataga atgaacatag
     3241 ccgattgttt tttcttccat ttaagttcac atcttttctt tgatttcatt ttaagtacaa
     3301 gttagctgtc gaagcgaagc tttctgaaca aaatttttcg caattgccgc ttcgttatgt
     3361 gtaaaattta cagggacgga acatacaagt cctgcccctg taaatcgttt ctttcaaata
     3421 agcatactga ttattcgatt ttgatgcgat ggctattcaa cgtcctttcg acgctaagtc
     3481 gaaaaacttt tttcacgaac tttttacatt ctgtcgtgtg aagttctcat caagacatct
     3541 aattgttgtt ctcttgtcaa gtcacggaat ttaactgcat aaccagatac ccggatcgtc
     3601 aagttcggat atttcattgg attttccatt gcatcacgca ataaatcatt actgaataca
     3661 ttgacattca aatgataagc tccttttgag aagtatccat ctaagacatt acgcaagttt
     3721 tcgattcttg tatcttgttc ttttccaaga cctgaaggat tgattgtttg ggtatttgaa
     3781 attccatcca atgcacagcc gtaattcatt ttagctgttg agttcaggct agctaataac
     3841 ccactttgtt ccgcattgta acttggattt gctcctggcg caagtggttt tccagcttca
     3901 cggccatcag gagtatttcc tgtattttta ccgtaaacaa catttgaagt aatcgtcaat
     3961 aatgaagttg ttggttttga gttgcggtaa gttttatgac gtttgatttg tcccatgaag
     4021 tattccaaga tccatgaaac taattcatct gcacggtcat catcatttcc gtatttaggg
     4081 aagtcgccat ccacttcaaa atcaactgct attccttttt cattacggat tgcttttact
     4141 tttgcatatt tgatcgctga caagctgtct gccgcatgag agatcccagc aatacctgta
     4201 gcaaatgtgc gttgcaagtc agaatccatc aaagccagct gagctgcttc ataagaatat
     4261 ttatcatgca tataatgaat gatgttcaac gtattgacat atagttctgc taaccaatcc
     4321 atcatattca tgaagttatg tttcacttct tcaaagtcta gtatttctga tgtgattgga
     4381 cgatattctg gtccaacttg ggcgccagtc acttcatcga ctccgccatt gatggcatat
     4441 aatagtgttt tagccaagtt agcacgagcg ccaaagaatt gcatgtcttt tccgacaact
     4501 gttcctgata cacagcaagc aatcgcacaa tcatcagaac cccattgttc acgaagctga
     4561 ttatcatttt cgaattgaat cgaagaactt tcgatagcga ttctgctagc atatgttctg
     4621 aatccttctg gaaggtgttc agaatacaaa acagtcaagt ttggttctgg tgaaggtccc
     4681 atatttgtta atgtatgaag cagacggaaa tcattctttg taactaatga acgaccatct
     4741 aatcccatac ctgcaatgga taaagtagcc cagataggga atcctgagaa taattggtta
     4801 tattcaggtg tacgcgcgaa tttgaccata cgtaatttca ttactaagtg gtcgatcaat
     4861 tcttgtgctt ctttttctgt gattactcca ttatccaaat cacgttggat atagatatca
     4921 aggaatgctg agatacgtcc gattgacatc gcagcaccat tttgtgattt gattgctgct
     4981 aaatatccga agtatagcca ttggacagct tcttttgcat ttgcagctgg tttagaaata
     5041 tcatagccat atttcgcagc catttctttc atttgcgcta atgcacgata ttgttcagtg
     5101 atttcttcac gtaaacgaat cacttcttca ctcattgtat gataaccagt catatcatga
     5161 tcttttttct tttgttccat caaatagtcg attccataca atgccacacg acgatagtca
     5221 ccgatgatac gtccgcgacc gtaagcgtct ggaagccctg taatgatttt gtttttacga
     5281 gcagcacgca tttcagcagt ataagcgtca aatacacctt gattatgtgt tttgcgccag
     5341 tcagtgaaaa tatgtgtcaa ttcatcgttt ggtgtatagc cattgctttt tagcgcattg
     5401 ttagccatat tgattccgcc gaacggcatg aatgcttgtt tcaaaggttt gtctgtctgt
     5461 agaccgacga ttttttccaa atctttatcc aaatagcctg catcgtgtga agtaatagtt
     5521 gatacgattt ctgtgtccat atcatagaca ccgttacgct cgaattggat atcatttaac
     5581 ttttgcaatt catcccataa tttttctgtt gcttctgttg ggccttccaa aaagctgtca
     5641 tcaccgcgat attcagtgta gttattttga ataaagtctc tagtgtctac gccttctttc
     5701 catttggtac ctttaaatcc attccattgc tccattgtat ggacctccta aatttctgtt
     5761 ttatgtaaca gtttttacgt gattagtata acacagcacc ctatctttgc aagggttttc
     5821 ttgtttttta tttaacaatt tttatgtttt atttacatat atttaaatca acgttgacat
     5881 accaacattt aagcattgtg aacactttca tctttttttg caaacgtata aggatttatt
     5941 aaaaatgaat gaaaaagaga cgccacctgt attaatacag atggcgtctc ttcattaaaa
     6001 tactacaaca gttacgactc gatgaaaatc tcaggagcat cgataacttc gatgacttct
     6061 ccaccttttt tctcatccat cgcaaatgat ccattcgatg ttcgatcacc tatagggaaa
     6121 tcagttgggt caatcgttaa ctgctgccct ttttgattca tcaaggttat ttcttttgat
     6181 cttccttccg acatatagat aatacggtgc ggattttttt tcagctcacg catgaccgtc
     6241 actccccgct tcgcacgtga agtttggctg atttcttgag caagcatgcg tttaacagct
     6301 cctcgctgag taacgattac gatcggcgta tcaccttctg ctaacacaag cagcccgttg
     6361 ataatcctat ctccatcttt caaattcata gacttcactc cagctgcctt tgctccaaca
     6421 acgggaacat ctgttaaagg atagcgcaaa cccattcctt gatgcgttac taagaaaaca
     6481 tctaagcctg gctgatcttc tttcagatac acagcaatca gttcatcttc ttccgccttt
     6541 agcttcatac agctgagcgg acggctctta taggtgcgcc atggttcgaa ctctgtcatt
     6601 cgtgtttgct tgatcaatcc attcttgctg atgaatacaa atgttttctc tgcttgaatt
     6661 ttttgatatg ggaaaacagc taaaatcgat tcgtctacag acagattgga gattgtttga
     6721 gaaatgtgct caccagcatc tttccatttc aaatcgggta gttcatggac agggcggtag
     6781 atcacatttg ctttatttgt gatcagaaga acatggtcca atgtactcaa ttcacctgag
     6841 tatagcaagt agtcgccttc tcgcatcccg atttcttctg gtttggaagc actataagaa
     6901 cgaaggcttg ttcgcttcac atagccttct cgcgtcacac tgacaattac gtcttcttgt
     6961 gccactaaga cttgcgtatc aattttgatt tcttcgattt cgtcttcgat tgtcgttaga
     7021 cgagcggaag aataattttt tttcacttct cgcaattctt ttttcataac agagaaaagc
     7081 tctttgtcat ttgaaaggat tttattcaac tctgtgattt gcgcaatcaa gctttcggat
     7141 tccttttgaa gctctgtgat atccgtgttc gtcaaacggt ataattgcaa tgtgacaatt
     7201 gcttctgctt gttcttctgt aaattgaaag acgtcgacta aattcttttt ggcgtctttt
     7261 ttgtctttac tttcacgaat cgttgcgatt acttcatcca gaatcgataa agctttcatc
     7321 aatccttcta cgatatgctg tcttttttga gctttggcta aatcgaattg actacgtttt
     7381 gttatgactt gctttcgatg ctcgatataa cttcttaaaa tgtctttcag tccaacttga
     7441 tgcggagtca tatggtcgat agcgaccata ttgaaattgt aattgatctg tagctcagtg
     7501 tttttgaaca aataattcaa aattccttga gcattggcgt cttttttcaa ttcgacgaca
     7561 atttgcagac ctgttctatc actttcatct cgtacttcag ctattccatc gattttctta
     7621 ttcaaacgga tctcatccat ttttttcacc aaggtcgctt tatttacttc atatgggatt
     7681 tctgtgatca cgatttgctg tttattaccc ttcattgcct ctatctttgt tttcgaacga
     7741 agaataactt ttcctcgtcc tgtttcataa gcttttttga tttcatcttt tccttgcaag
     7801 atccctcctg ttggaaagtc aggtccagga atatattcca tcaatttttc aaggctcgct
     7861 tgtggatgat cgatcatata gattgtgcca tcgatcactt cagctaagtt atgagtcggg
     7921 atttctgttg catatccagc agatatacct gtcgatccat tgacgagaag gtttgggtat
     7981 cgagctggaa ggactgttgg ttctttttct gtatcatcaa aattccacac gagatcgact
     8041 gtttctttct cgatatctgc tagcatctct ccacttaact tggataatct ggcttcagta
     8101 taacgcatcg cagcaggtgg atcaccgtcc atactcccgt tattcccgtg catttcgatc
     8161 agtacttccc gcaacttcca gtcttggctc atgcggacca tcgcttcata aatactgatg
     8221 tcaccatgag gatgataatt ccccatgata tttccgacag attttgctga tttacggaat
     8281 cctttgtcat acgtattgcc atctttgttc atggcaaata atatccggcg ttgcactggc
     8341 ttcaatccat cacggatatc aggcagtgca cgttcttgga taatatattt ggaataacgt
     8401 ccgaagcggt cacccatcac ttcttctaaa gttaattctt gtacttcttg tcgattttcc
     8461 atcaggtgac ctcctattct acttcaaata actgattgtt ttcattttta tctgctcgtt
     8521 cttcatctaa taaatcatta gaaactgaag gagagatttc agtatcctct tttttatcta
     8581 agatactgcc atcttcttcg agcgtaaatt gcacgtgatt ttcgatccat tttcttcgag
     8641 gttctacttt gtcacccatc agtgtggtta ctcgacgttc agcttgcgca gcatcatcga
     8701 tacggacgcg gatcaacgta cgggaagtcg gatccatcgt tgtttcccac aattgttccg
     8761 cattcatctc tccaagtcct ttatatcgct gcagcatata tcctttgccg acttttttaa
     8821 tcattgctgc caattcgtca tctgtccacg catattcaat gacttgcttc tttccttgtc
     8881 ctttggatac tttatataaa ggcggtaacg cgatatatac tttcccagct tcaatcagcg
     8941 gtttcatata acgataaaag aaagtaagca gtaatacttg aatatgggcg ccgtctgtat
     9001 ccgcatcggt catgatgatt actttgtcgt aattacagtc ttcgatagaa aactcaggac
     9061 cgactcctgc accaatcgta tagatcatcg tattgatttc ttcatttttc aagatatctt
     9121 gcattttagc tttttcggta ttgatgactt ttcctcgtaa aggtagaatt gcttggaact
     9181 ttctgtctct tccttgttta gcagatccgc cagcagaatc cccttcgact aaatacaatt
     9241 catttttctt agggtttcgg gattgtgcgg gtgtcaattt tcctgaaaga agagattcgc
     9301 cttttttacg cttcttccca tttcggcttt cttctctggc tttacgtgct gcttctctcg
     9361 cttctctggc tttgattgct ttacggacca acatctggct catttcgcta ttttcctgca
     9421 aataaaagcc catttgttca ctgatgacgt tatctactac ggtacgagca actggcgtac
     9481 caagtttttc ttttgtttgc ccttcaaatt gcagaagatt ttcaggtaca cggatagaaa
     9541 gtacagcagc taacccttct ctgaaatcac taccttccag attcttgtcc cgttctttca
     9601 gcaaaccaac ttttctcgca tattcattat aagatttcgt catcgccgct ttcataccag
     9661 cttcatgggt tcccccatct tttgtccgaa cgttattgac aaaagataaa acattttctg
     9721 aataaccgtc attgtattga taagcgacct ctacttcgat accttctttt tctcctgaaa
     9781 aataaacaac tggtgtcaat gtatcttttt cttcattcag ataatcaaca aattctttga
     9841 ttccttcttc gtaatgaaaa atttccttga ctggttcttc tccacgaaga tcagaaagag
     9901 agattttaac gccttttaga agaaaggcag attctcttaa ccgttcggct aaaatttcat
     9961 atgaaaattt cgttgtactg aatattgtat catctggtaa aaaatggaca gtcgtcccgt
    10021 ttgctttttt tgtttttcct atctttttca aagtaccgtc aggtttaccg ccgtttttaa
    10081 atttctgctg atactctacg ccatctctaa cgatcgttac aattagccat ttcgataagg
    10141 catttaccac actggctcct acaccgtgca gtccaccaga agttttgtac cctccttgac
    10201 caaactttcc gccagcatgc agcacagtaa aaatcacttc aactgttggt attccggaag
    10261 catgcattcc tacaggcatc ccacgtccgc tatctgcaac agttatacta ttgtcttcat
    10321 ggatggtcac atcaatctca ctgccataac ctgataatgc ttcgtcaact gcattatcga
    10381 cgatttcata gactaaatga tgcaagcctc ggctgtcagt ggatccaatg tacatccctg
    10441 gtctttttct aactgcctct aatccttcca atacttggat ggacgagtca ttgtattcgt
    10501 tgtttacttt ttttgccaag gcaaacgctc cttcaataat actttgcggc aaaaccgcac
    10561 cacgattatc atactagaaa aggtcgtgaa aaaaaagagg gtagacgaga aatcaatttt
    10621 aattatctcc taaccgcttt ttcgacattc ccctctatcg atcatctctt ctttgtggtc
    10681 atttttattt ttggttttct ttcaacttac caagttcaat cttaatacaa cgatccatta
    10741 cgatatctgt acgtcctgct tttcttagca tctcagctgc ttctttgttt tcaatcccta
    10801 attgtgccca gaacacttta gcatcagttt tcaaaaaatc acctgctatt tcaggtaaaa
    10861 attcactccg tctaaataca tctacgatat cgattggatc atcgatttct gtcaaattcg
    10921 catagacttt ctcgcctaga atttcttcac cagccaataa tggatttact ggtatgattt
    10981 tatatccatt gtcttgcaat acctgtgcaa ccatgtaact tgttcgttct ggtttattgc
    11041 tcaagcctac gacggcaata ttttttgctt cttccaaata gttgaaaatc gtttcttgtg
    11101 ttggattttt tacagacatt tctgccaccc cttgcttttc tttttattcc atctattata
    11161 cttgtatctt tcattttttc aattgttcct gttacctatt catgctaaaa taaaggatag
    11221 ttttcaactt gaaagagggt aaaaaatgaa attgatctta ttacttattt tagcatatct
    11281 tttaggttct attccttccg gtgtctggat tggcaaattg tttttcaaaa aagatatccg
    11341 acaacacggg agcggtaata ctggaacgac caatacattt cgtgtattag gcaaaacagc
    11401 cgggattgtt gtcctgctta tggatatttt aaaaggtaca ttggctactt gtttgccgat
    11461 gatcttccac ctttctggga ttaaccctct ttggtttggg gtatgcgcca ttcttggcca
    11521 tacatttccg atttttgctg ggttcaaagg aggaaaagct gttgcgacaa gtgcaggaat
    11581 gcttttagga tttaatcctg tattttttgt ttattcttgt atcatcttta tcgttagttt
    11641 attttgtaca agtatggtga gtttgagcag tatgatcagt gcagtattga tcactttatc
    11701 tacgatcgtc cttccttatg tagctcctgt gattttggct aagcccaatt ggttactgac
    11761 gatcattgcc tttttagttt cttcctttat cttttatcgg cataaagaca atatcaagcg
    11821 tatcagaaac catactgaaa gtcgaatccc gtttggtttg aatagcagca agaaaaaatc
    11881 ctgatacttt ttcattccaa agagataaaa cgggagtgtg acaaatcgat gtcacactcc
    11941 cttattactt acaggatagc ttttttacac accttggtaa acggtgttcc ctgctaactt
    12001 ctcggtcaca acctcttact tcactgtgat ggaatatttt gtcttgaaga tttcatgggc
    12061 acctagttga ttgatcccta ctttttccat caagtttcca ctactgttca ccgtgtcagc
    12121 gattccgcac cacggttcga tacaaacgaa aggcgcttct tttggataag gagaccagat
    12181 ccctacataa ggcatatctt tatagcttaa agttacgcta tgggaagatt tttcacttcg
    12241 aatggcgtac gcatttagac cccttgtttc aaaaaccaag gcatcttgct caaaaagttc
    12301 acgattcaaa gccagattcg tatttgtctg acctaacgtc ttttgatcca tatcgatgaa
    12361 tgggcctttc aatggtaggc gtaatcttga tttcaatgga gaaaatgcca gatagaaatc
    12421 ttcaaatgac aatccttctt caagaggtac attgaaagca ggatgtccac cgatagaaaa
    12481 gaacatttct ttttcaccgg tatttgccac ttgataatga accgtgatgc cgtctcctcc
    12541 taattcatag ctgatcacta attcaaaatc aaatggatac ttttctaatg tctccggcgt
    12601 actccttaag atgaaactag ccatttcttg tccatgttca atgacttcaa aatccatatc
    12661 ccgagcaaat ccgtgttgcc ccatttgata tgttttccct tgataaacat actgatcatc
    12721 ttttaaacgt ccaacaaaag ggaataaaac cggtgcatgt ctgccccaat acgctggatc
    12781 accttgccag atatactcta aaccatgttc ttttgatttc agactgatca attccgcacc
    12841 gtgttcagcg atttcggcga tcagctggtc attttgaata ataacagtca ttgccattcc
    12901 tccaacttcg acttactttt taaaatggga aggctggaac aaacatttct atctgcccca
    12961 gtccccttac ttctaataac tgtgttttgc taactcgtct ttaaaacggg aattcaatac
    13021 ttttaaataa gttcccttca tgcctaacga acgagattca atgattccag ctgattccaa
    13081 ttttcgtaaa gcattgacga tcacagaacg agtgatgccg atactatcgg caatattaga
    13141 agcagtcaga cgaccttcat ctccatccaa tgcttcaaag atagcttgta cagccttcaa
    13201 ttcgctataa gataatgtgt tgattgccat ttggacagcc gttgcactcc gtacatctgc
    13261 ttcgatgctt cgagacttct gataaaggat ctgcataccg acaaccgtag ctccatattc
    13321 tgctaagact agatcgtcat ctgcaaacga ttgttccata cgagataaga taatcgtacc
    13381 caaacgttcg ccagctccaa agatcggaac gacagtcgtc agaccaaatg gatatttctc
    13441 tcttgactct accggaaatg cagtaatatc actagtaatt gggatattag cttcagtttt
    13501 catcaactgt gccactgtat cagtataaga ttcaggaaat tgtttctcaa caaacattgt
    13561 tttgattcgt tcattgttca catcgtgacg ttcattataa cctagtaata ctccgtcact
    13621 tcctatgata taggtgttgc tgtcaagaat accacctagt gtgacagcca ttttatcgta
    13681 aggcaaatct gcttgcatgt caaaagtatt cttttgctgc aaaagtgtgt ttatcttgcg
    13741 ggttttcgtt agcaagtctg tcattgtcgt cctccgattt tttataaaat atagcgactt
    13801 aaatcttcat ttgccgcaat tgagccaagt ttgtcatcca catatgcttc tgtgatcgtt
    13861 atttctccca tttgcatatc tggtgcttca aataatagat cttctagtag tttttccaaa
    13921 atggtatgca gtctgcgtgc gccgatatta tctgtgtcac ggttgacatc gaaagcgatt
    13981 tgagcgatcc gttcaattgc ttcttttgta aacgtaactg acacattttc tgtaccgatc
    14041 aacgcgacgt attgttttac taaagcatta tttggttcgg tcagaatctt cacaaaatct
    14101 tcagctgtca aatcatctaa ttctacccgt atcgggaagc gtccttgaag ttctggaatt
    14161 agatcacttg gtttagacaa atggaaagct cctgaagcaa tgaataggac gtgatctgtt
    14221 tggatgatcc cgtattttgt gtttacttgt gaaccttcga caattggcaa tatgtctctt
    14281 tggacgcctt ctctggatac ttctccagat tgctgtgatt tagaagtgat cttatcgatt
    14341 tcatcgataa aaataattcc actttcttcc gctaatttga ttgcctcact atggatatca
    14401 gcatccttga ctaattttgc tgattcttcc ttgatcaata actctaaagc ttctttgact
    14461 gttaccgtcc gttccacttt tttcttcggt gtcaaagcac ctagagtttc atttaggtcg
    14521 atccccattt gctccaatcc attgttcatc attggtgcag gtttcttttg gtcttcaact
    14581 tcaatggtta cttcacgact atccagtaaa cccttttgta gttgttccaa gactgtacgg
    14641 cgattgattc gaatatcttc tgtcacttct tcttgcggtt cagcggtatt ttgctgacta
    14701 gcattaaaaa gattcatcat ttgttcaaat tgattagtgg attgtttctg ttcttttttg
    14761 ataccaggta ccaagatttt taccaaacgt ttttctgcat tttttttagc acttgtgtat
    14821 acacggctgt actgctcttt ttctacgatt tggatcgcat tttctactaa atcccgaacc
    14881 attgattcta catctcttcc gacataaccg acttcagtaa attttgttgc ttcgactttg
    14941 acaaatggtg cattgacgat ttttgccaaa cgtcgtgcga tttctgtttt accgacccct
    15001 gtaggtccga tcatcagcat attttttggt gtaatatctt gttgcatttt ttcatctaac
    15061 tgcaaacggc gatagcggtt acgcaaagca acggcaacag atttttttgc tgcgtgctgt
    15121 cctacgatat attcatctaa ttcacttacg atttgtcttg gtgtttgttt taattcatac
    15181 atatctactc acctcttaca gttcttctac gataatatta tgattagtaa agatacagat
    15241 atctgcggca atatttaacg cattttctgc aatttctttc gcactcatgt cgttttgagc
    15301 atagtttttc attgctcggg ctgcagccaa cgcaaaattc cctcctgatc cgatagctaa
    15361 gataccatca tctggtgtga taacttctcc tgtacctgaa acaagaagca tttctttatc
    15421 attcattacg atcagcatcg cttcaagttt ttgcatagat tgctgtgtcc gccattcttg
    15481 agctaattcg acagctgcgc gttgtagatt cccgttatat tcgtttagtt tgccttcaaa
    15541 tttttcttct aaagtaaacg catctgcaac acttccggcg aaacctacaa caacttctcc
    15601 attgtagata cgtcgtactt tctttgcagt gcctttcatg acaacagatt cacccattgt
    15661 tacttggcca tctccagcca tagcaaattt cccgtctttt tcgacggcac agatagtggt
    15721 tgaatgaaat ggtgattcga ccatgtttgt ttcctcctaa atttgttctt ttccttattt
    15781 ttacgctctt ggatggaaag aacgatagtt tttttgtaaa ctttcttttg ttacatgggc
    15841 atagatctgg gtagtcgata aattggcatg tcctagcaat tcttggactg tccgcaaatc
    15901 tgccccatta tttaataaat gagtagcaaa tgtatggcgc agcatgtgag gatggatatc
    15961 actatccaaa ctgctttttt tgatcatttg attcaagaca tattcaattc cagtaggcgt
    16021 gattggtttt ccatgatgat tcacaaaaac gatatcatgc tcttcgtgat attttgtcat
    16081 caatacctgg cggccttccc tgaaatattc ttgcagagca tcttgagcaa aagaacctag
    16141 aggagcatat ctctctttgt tccctttacc atggatcaac atgacctctg aatcaaaatc
    16201 aatgtctgat accgacaaac tgctacactc acttaaacgg atgcctgacc cgtaaaggac
    16261 ttccagtaaa gcgcggttcc tcaaatccaa aggactatct cctgctacgc tgtcaaaaag
    16321 tgcttgcatt tcattttcat aaaaaaaacg tggcagtctc aaatttttct ttttgagatg
    16381 aacgtaagaa aatggatttt cttttatcac ttcttctttg agaagatact gataaaacga
    16441 acgtaggctg gctatcttgc gactgataga atttctgcta tagctaggac gatgatcagc
    16501 taatgcactc aaatagacac gaaccgtaaa atattccgcc ttcagcagat cagcgtctcc
    16561 agattcctcc aaaaaatgtt tgaaatggag aatgtcttct tcatatgctt ctttcgtttt
    16621 ttctgaatat cctctttcga caatcaaata acgcaaaaat ttttgttccc acgtggcttc
    16681 tgtcattttc tcaccttcct tttgtcccag agaataattt agcacagcgt ttataaaaag
    16741 acaaataaat tgtcagaatt taaccaatat ttctaagttt gttcacaatt ggcgcaattc
    16801 ctcacatttt gtttgagaaa ttcttaagaa aaacgcaaga aaaagagcga gactatccgt
    16861 ctcaccctct tcatggagtt tccttactca tttgggattg cagttttttc taattctgtt
    16921 tttattgcct cattagcttt taaagctcgt tgtgcaattg cttcatatct tgcttttttg
    16981 tctcgaatgc gctctggcag ttcaggaaac agaccatagt tggcattcat cggttggaaa
    17041 tgttttcctt ccgcatgagt aatgtagtaa gccatacttc caatagctgt ttcttgtgga
    17101 aactcgactg gttccatttc ttttgctaag cgtgcggcgt tgattccagc aagtagtccg
    17161 ctcgctgcac tttcaacata gccttctaca ccagtcatct gacctgcaaa gaacagatct
    17221 tcgcgtttcg ttgattggta agtcggtttc agcaattctg gcgaattcat aaagctgttt
    17281 cggtgcatca caccatagcg aacgaattca gcattttcta acccaggaat catccggaaa
    17341 acacgttttt gctcgcccca tttcaagtga gtctgaaagc ccacgatgtt gtataaagaa
    17401 gctgcagcat tgtcttgacg cagctggata acagcataag gacgtttgcc agttttagga
    17461 tcttccaatc caactggttt cataggtccg aaaagcatcg ttttgaatcc tcgctgtgcc
    17521 attacttcaa ttggcataca tccttcaaaa tatttttctt tctcaaaaga tttaagttct
    17581 gccacttcgg cattgattag tgcctcatgg aaagctttga attcctcttc tgtcatcgga
    17641 cagttcaagt aagctgcttc tcctttgtca tagcgggact tcaaatatac tttatccata
    17701 tcgatcgtag ctttgtctac gattggtgca gctgcatcat agaaataaaa accatctgaa
    17761 ccattgaatg ctttgatgct ttctgctaat ggatgagaag tcaaaggtcc tgttgctact
    17821 acggtgattc cttccggtat ttcagtaatt tcttcgttta tcactgttac taatggatgc
    17881 tctttgactt ttcgggtaat tgtttcagaa aaagaatcgc ggtcaacagc taaggcacca
    17941 ccagctggca ctgctgtttc atctgccgaa gtgattacta ccgaattcaa tcggcgcatt
    18001 tcttctttca ataaccctac tgcattagcc aaactgtttc ctcttaatga attggaacat
    18061 actagttcag caaaattact tgtgtgatgc gcctcagtcg atttgactgg acgcatttca
    18121 tataaacgga cagggactcc tgcttgtgcg atctgccaag cagcttcact tccggcaagc
    18181 cctgctccaa caacatttac cattttcaat gaaagaacct cttttctatt atttttggat
    18241 gtcttcttcg taatctccat ttacacagac tacttgttta ccgcctttga ctttcttctc
    18301 gaccagatat ccgtcacatt ttggacaatt tctgcccact ggtttatccc aagaagtgaa
    18361 ttcacattct gggaaacggg aacaaccata gaatagtctg tttttcttag attttcgttc
    18421 aatgacttgt ccttcatgac atactgggca agtcacaccg atttctttta cgattggttt
    18481 cgtattccga caatcaggaa aattactgca agcataaaac ttcccatatt tccctaattt
    18541 tatcaccatc ggatgtccac agacatcaca atcgaatcct gctggttcat ctttgatttg
    18601 aattttttcg attttttctt ccgcattcgt cagttctttt tcaaacggtt tatagaaacg
    18661 atcaaccact ttgacccacg cttccgtgcc ttcttcaatt ttatccaaat ctccttccat
    18721 ttctgctgtg aaatggatat cgacgatttg agggaagaat tcacagatta atgaattgac
    18781 aatttctcct agttcagtcg gctcaaatct tttttgtgtc aattttacat agtagcgtct
    18841 ttggatcgta tcaagtgttg gtgcataagt ggaaggtcgc cctaccccgt tttcttctag
    18901 tgcacgaatc aacgtagcct cactaaaacg tgctggtggt tgagtaaaat gttgttttgg
    18961 ttcaatatca acagattgga ctacatcgcc ttcttcaagt tctggaagaa tattttcttt
    19021 ctcttctttg ccgtcatctc taccttccac atacacttgc atgaatcctt tgaatttgat
    19081 ttttgaaccg ttcgcaatga agatgacacc attttgttct aatgtcactt tcattgtatc
    19141 taaaatagct ggtgtcatct gactagccac aaaacgtgac cagatcaatg tataaagttt
    19201 caattgatct ttatctaaat attgtttgag ttcatctggt gtacgaagca cactcgttgg
    19261 acgcacagct tcatgggcat cttgtgcgcc ttgagcattt ttgatctttc ggtgatcatg
    19321 tctagaaaat tcttttccat acgtatcttc aataaatgct gcggcctctg cttttgctgt
    19381 atcggcaatc cgggtagaat cagtacgcat gtatgtaatc aagccgactg ttccttgttt
    19441 acccaaagtg attccttcat ataattgctg tgctaccatc atggtttttc ttgttcgaaa
    19501 gtttaactta cgggcagctt cttgttgcag gctacttgta gtgaaaggat tcgcagggtt
    19561 tcttttgcgc tctttctttt ctactttttt aacttcgaag tctgttccat caattctagc
    19621 agtgacttct tttacacttt gtgcatctgg taatttcttt ttcttaccgt cgattcccca
    19681 gaaatttgct ttgaatttct tgcgagcttt tttaaaatta ccgtcgatgc tccaatattc
    19741 ttctggaaca aattctcgga tctctttttc acggtcaata ataattttta aagcgacaga
    19801 ttggacacgt cctgcactta accctttctt gaccttacgc cagagaatag gactgatcga
    19861 ataaccaacg attctgtcta aggtacgacg agcttgctgt gcatctacta aatctacatc
    19921 gatcgttctt ggttccttaa aagctgcttt gactgcgtct tttgtgattt cattgaagac
    19981 cacccgattt ttttctttca gatccaaccc aagtaggtac gctaaatgcc aagcaatcgc
    20041 ttctccttct ctatccgggt cacttgccaa gtaaactttt tgagcttttt ttgctgcggc
    20101 tttcaggctt ttgatgacat cgccttttcc gcgtatagaa atataatggg gttcataatt
    20161 gttttcaaaa tcgataccca ttttactttt cggtaaatct cttatatggc caacactggc
    20221 cattacttta tagtttcgtc caagatattt ctcaattgtc ttggcttttg caggtgattc
    20281 tacaatcact aaatatttat acgccattac tgaatggact cctttccatt gtcgtgttcc
    20341 tactattaaa agaggattca tacaaatcgt agctaatcat atccattcag aaaacgtttg
    20401 tcaagaaaag caaatgaaaa gtatggtgtt attctttaaa ttctgccaag atatcttcac
    20461 ccgaaaccgt gcaaactgca ccgtcttgga tcaaatgatg acatccggta gaatgttctg
    20521 ttaaaatatt tcctggaaca gaaaaaactg ttcttccaag atccaatgct tgctgtgctg
    20581 ttatcagaga gccgcttttt ttcttggctt caaagacaca tgttccttta gacaaagctg
    20641 cgataatccg atttctcatt ggaaaacaat gctttttcgg gccggattga ggaggatatt
    20701 cactcaaaag aagatgatca tttgcaatca cctcttgcaa gtcacgattt tcagcaggat
    20761 agacttgctc tatccctgtt ccaatgactg cgattgtccg tccaccatga gagattgctg
    20821 cttggtgacc gtatgtatct atccctttcg cgcagccact gacgatcaca tatccagctt
    20881 ctatcactgg ttttagtaaa taataaactg tttttttggc taaagcagaa gtgtgtcttc
    20941 caccaacaac gcttaacatg ttacaagaaa gtaaagatag atcaccatta taaaacagta
    21001 caattggcgg ataggtcaag tgaagcagct gagggggata tttgggatca aagcaagtga
    21061 taaacgactg tttcgattgg attttgcccc agttagcgtg aatttcctgc caacttttgc
    21121 gaaacagctc ccggtgtttg gttattttac ctatcttaat gatgtcttca aatccgattt
    21181 ctttataagg atactgcatc atccagttag caagtgccca ttttccttga ctactgattc
    21241 cttttgtata agcaagtttc aataaatttt cttctatttg atacatcata aaaccgcctt
    21301 tcgtctctct ttctaataag atacgtaaaa gcggctgttt tttattgtaa atattttttt
    21361 acaggtgcaa aacttttacg atggattggc gtaattcctt gtcgttcaag tccttctaag
    21421 tgttcctttg ttccataacc tgcattatgc gagaaaccat atccaggata aagcacgtca
    21481 tattctttca tcaattggtc tcgatatact ttagcaatga tacttgcagc agcaatcgac
    21541 acagatcgtg catccccttt gattattttt tcctgctgaa taggcaaatc caaggtcatc
    21601 gcatcgatca acaaatagct tggtacaatg gacaattttt ctactgcttg gatcatcgct
    21661 aatttacttg cttcataaat attcacatca tcgattgtct gctgatcaac gatcccgatc
    21721 ccgattgcca gggctttttc ttgaacttgt tgataaagaa gttctcgctt tttctctgat
    21781 aattgtttgg agtcattcag ccctaatatg atctcatttt tcggcaagat aactgcagct
    21841 gccacgacag gtccagctaa tggtcctctt cctacttcat caatgccggc aatccattgg
    21901 tgaccttgtg cgtacccttg cttttcaaag caaaacattt cttcatattt ttccttaatt
    21961 aatgcttcct ttttcaatcg tcgttcaaaa gaagccagtg cttgctgcac gcctttgcgt
    22021 ggatcatttc ttaatgattc tagtgtagga tcatctattc tctgtatgct tttcaatcgt
    22081 tctttgatac tttggatgga ttcagtcatc acttttttgc tccatttctt cgcaacgatc
    22141 cagtgtgtat cgtccaagtt ttccttgacg aatatcatgc acgactaatt cgctgccacg
    22201 atcatagtct tctttatacc cacgttttgc tgtaatatcc atcagtaatt ccggtgccaa
    22261 tttttcttct tgctcgattg ataaaccata acgatcgctg attcttcctg aataatatcg
    22321 ggcaaaaaag tctaatccgt aaatcgctaa atcatctaaa tggacaagct ggtctttgat
    22381 cgcgcctgtc agcgctagtt ttttgccgat ttcttcatct tcaaatttgg gccataaaat
    22441 ccctggtgtg tctaacaatt ccaactcatt acctaaacga agccactgct gaccttttgt
    22501 tacgccaggc ttatttcctg tctgtgcaat tttcttgcct actagtcgat tcatcaacgt
    22561 agatttccca acatttggaa tacctaagac cattgcccga atagcgcgag gcttgatccc
    22621 ccgagcagca tctcttgccc gtttttcttt caatgcttct ttagccgcag gtactagacc
    22681 tttaattcct ttactttctt gtgccgtgat agctaatgca agatggcctt gtttacgaaa
    22741 atattcttgc cacagctttg tctgttgtgg atctgccaga tccgctttat tcaataaaac
    22801 aaggcgaggt ttttgctgaa tgatctgatc tagcattgga ttacgagaag ataaaggtaa
    22861 tcgtgcgtct accaattcaa atacgatgtc cacatatttc attttttcag aaacttctcg
    22921 tcgggctttt gccatatgtc ccggaaacca ttggatggtc attgttctct ccattccttt
    22981 cataccggaa tattccccgg ctttacttgt ttttttcttt ttcaatataa attcactttt
    23041 ttattataaa gaaattccat ctattagtta agtgaaagtg aaccagtcct cattctatca
    23101 catcttcact tttttgatga tgcaaatttt tattttggtt tctatatatg aatctaaatt
    23161 tttgacagcg tttcctaaat aagagatgat agacgaacaa aacagaaagg agacgaaaca
    23221 aatgaatagt atggtttttg ttaattttcc tgttgctgat gtcaatcgtt ccgttgcttt
    23281 ttatgaaaag ctgggtttta aaaaaaatga agaattttct actgaagaag ctggttcaat
    23341 ggtatgggat gacacttttt ggataatgct tctctctcat gatttttata aaaaatttat
    23401 aaaagataaa gaaatagctg ataataaaaa aacaagtggt gctttgattt cgtttagtgt
    23461 tgaaaatgcg gatgaagtaa aaaaatttgc tcaaattgca aaagaaaatg gtggtacttt
    23521 ccacgaagta gatatgggaa tgcctgaaga agaaatgttt tcattagaag tccaagatct
    23581 agacggaaat acattagaac ccgtatggat gaagatgtaa gcagataact aatctgacgt
    23641 tttttataac aaaaaaacaa aggcggatga tacgataagt attctccgcc tctatttttt
    23701 ttattcgtac aatctctttt ttacagttta taaaagcagt cttctcaccc tttttttaat
    23761 tgttagatgc cagtgtatgt aaatcaccaa tgtgtcatga cacattggtg attttatggt
    23821 atccttttat tattaactga caaaggagag aatattttga acactttgat tgcaaaagac
    23881 gtttttagat tgcccgaaat gaatgcaaga ttgttgtcga cctctgctct tttattagcc
    23941 cttgatgtca tcttatacaa gatagcgatt ggtcctgctt attttcaaat cacattcgga
    24001 tttttaagta tggcgcttat gggttatcta tatggaccga tctgggctgg tttgcttgaa
    24061 atgttgtcga acactttaaa tttcacgata tttggttcag gaacgtttca agctgctttt
    24121 cttatcacgg ctttccttgg tggatttatt aatggcttat ttttatatca taaaaagata
    24181 aacctgcctt ccgtcatcgc tgcccaatta ttgattatga tcccagtcag cctttttatc
    24241 aattcttggc tgatgtctgt tttgtttggt gcagatttca aagtaatttt tctaggtaga
    24301 ttcatcagga atatgatcca aatccctatt caaataatgg ttgtttattc atttatcaaa
    24361 actttagagg ctagaaaagt gtttaaacga gctgtttgat tttacgtact aaggtagtaa
    24421 actgattttg gattaaacaa taaagcgtgc agtctcaaca gactgcacgc tttattgttt
    24481 ctcactggat ccattttatt tcatcaagtg gataatagac aaatcttgct ttacctagaa
    24541 tatcagtttt attgatcgtg ccaaacgaac gactatcttt tgaaactctt cgattatctc
    24601 caagtacaaa ataattatct tccggaagct tggattgtcc cgttagctct tgtagtgtaa
    24661 agtccgtcgt ataggatgca tttgcatgat ctgatttcag gtttttagtt agataaggtt
    24721 ccttaactac tttcccattg atcttcaatt gatcattttg gtagctgaca ttttctcctg
    24781 gaagaccgat tactcgtttg atataaatcg tgccatctgc taattgaaaa acaacaatat
    24841 caaatcgtct gatctccgaa aatttttcca tcacaaccat atcaccttgc ttcaacacgt
    24901 tttccattga attgccttcc actggtaccg ggatgaataa aaatccccgc aacatgaacg
    24961 caaggaatac agaaacaagt aagtatttga atacaagcca gaagcgatta atatagcgtt
    25021 gtttttttgt caatctctat caatccatcc ctcttttttt cattctttct ttattataag
    25081 aaaaatatca aaaaaatgcg actagatagc tgaaataaaa ataattcttt caattaggct
    25141 attggacaaa aaactttttt gatcataaag tacaaaacta tctcttatat gtcatgatta
    25201 ttttctaaat atttttccca tgcttcgtca aagatatcca tggacggcaa atagtcgaca
    25261 ttcagttcca gataattaga aatttcttcg tagctagagc tgtgcttagg aaattggatg
    25321 tctttaccgg cttctgtagc gaaaacagat aaagcatcat gtgtgccacc gcctcgcagt
    25381 gtcattaaat aatgaaaaaa gcttcgattc acccttcgtt cctccaattt tcttcgataa
    25441 aggcagcccg gcgtgcatgg tttcttttaa aattttcagg atgcttttta taatactctt
    25501 gatggtcttc ttctgctaga taaaatggtt gggctggttc gatttttgta acgattggct
    25561 gttcgaaacg tccactttca gctaactgtt tcttactttt ttcagcaatg atccgctgtt
    25621 cttctgtcaa ataaaagatc accgggcgat aattgtcacc gcgatcctcg aattgtccga
    25681 aagcgtcagt tggatcagtt tgctgccagt aaagttctac taattgttca tatgaaatca
    25741 atgttggatc atagataatc tccactgctt ctgtatgtcc agtcgtttgg ctttttactt
    25801 gttcataagt cggatctggt acatgccctc cagtatatcc tgacatcact gtatggatac
    25861 caggaagcgt gtcgaaaggc tggatcatac accagaagca gcctcctgca aatattgctc
    25921 gttccattat gattccccct ctaatactac tcatccgatg attttttatt ttcttttgtc
    25981 ttgctttcag tactgctggt gctagttttg ttggtatttg agttgtttga agcatcagag
    26041 gtatcttttg gcaaatatag actaaaccga atgtcatcat ttactaagtc gattttatct
    26101 gctttaatat acatcccgtt ttgcattcgg aattgatcca acctaagcat gatagtcaga
    26161 tcatctgtat tgacttcgat ccaatctggt aatttatagt ttctcttgat catattcatc
    26221 acatctttga ttggcaaact caatgttccg atagaaagac ttctagcttt tagttggaca
    26281 tttccgtttt ccatcacata cggatcaaaa tataaataga aatcgatagg aaaacctagt
    26341 acttcgaaag taccattgag tagtgcttca ttttccaaat aaaatttata ttcaatatca
    26401 ctatcttttt gatactcact aaggaaaaag ctgatgattt gattgacttt ttctttattt
    26461 gaattgatcg ttaagacagg atctccttgt ctttccgtaa gagctggtat ttctgggagt
    26521 tctggttccc gattagcaaa aatacggctg cctaaaaata cggtcgaacc aagtactacc
    26581 ccaagaagga taaggaaggc gaatttccag taatttgttt tctttgtttt gtttgaagat
    26641 acgtcagatc ttgttttcat gtttattgat catcctcctt ctctaaccat tggttttgtg
    26701 tctcgatcag ctgatctctc actgcatttg ccatcaattg ataacctaaa ttatttggat
    26761 ggaaatgatc ttcttcatag agcacattat ttttgatgcc atttagattt tctgtcgtgc
    26821 tagttgtttg atctgttcct tcttctgtga cacctacttc ctgattcaat ccttgataaa
    26881 gcaaatcatt gattgggata aagtagcagt tcggcatttt ttttgtcacc gtttctgttc
    26941 ctttgttcca attgttaaca attgtctgca tgtcagtgat ctcaggaaag ttcaaataaa
    27001 atggattgta gatgcctaaa atgtaaatag gtgcggtttt attgagggat cgaaattctt
    27061 ccaatagttc tgtgacattt tcctgatagt ttttcagtgg ctttttaaag gaattgaccg
    27121 ttaacccgaa taaattattt tggataactt tcatcaaatc attaccgcca acagtcagtg
    27181 tgataaaatc agctgttttg atattgtttc gaatttcttc ttttgttttt actcgcttta
    27241 agatctggtc acttcgttca ccatttacac catagttttc tgtttcaacc gcggtcaaat
    27301 tataacggtc ttttagatca tttgcgacaa ggggaacgaa tcctccttgc ttggtttgat
    27361 ctcctactcc ttcagtcagc gaatctccga tagctatgta gtgaagtttt tcttttttat
    27421 ttggatcttc tctcacagta gttactggtt tcattagtgg gccagctttc ggtatagaag
    27481 cagctaaacc tgcatagatg atgatcgcaa ttaataatgg gaacaaaacg aggatcaaat
    27541 gtcgtttcgt taatttcatt ttttcacctc ttgtattcga ttggttctaa tgttatcaaa
    27601 aattttatca aaaaggtagt ctttatgaaa aaagaaaaca attattttcc taattttata
    27661 aagaaaaaga gaataagctg caagcctttc aggctgaggg cttatcctct tttcgactaa
    27721 tctacataat acatgattgc aaacgcgtct ttaccagtat gcgtagcgat aaccggattc
    27781 gtatgcagta cagggatatg catgtccggg aataattctt gcaaaccctc tttgaattct
    27841 tgcgccaatt cttttgcatc cgcatgtgaa ataccgattt gtcgcacatt tggcaattct
    27901 ttcagttcat ttttcaaatt attaaaccat ttatcgaacg ttttctttcc tcgcccctta
    27961 gttacaggga ttaattcaga atgggcgaaa ttcatcacca cgcgtatgtt caaaacacta
    28021 gacagcaaac cagttgttcg gctgattctt ccacctttta ccaagttatc tagtgtggat
    28081 attccgatgt ataattttgt attgtcttgt acttttttga cttcttcaag gattttctct
    28141 actgttttac cttcttttgc taattcagct gctcgaatta cctgaaaaga taatccttgg
    28201 tcagtggtat cactgtcgat aaccgttact ttcgtttttg ttagattact ggcttgtctt
    28261 gctgcttcta ctgttccact caagcctttt gtcatatgga tcgaaatcac ttcactgccg
    28321 tcttctccta gctcatcata catcgagatg aattctccaa ttggtggttg gcttgttttg
    28381 ggcagatttt ttgctttcgc catcatttcc ataaatcttt cgccgtctag ttggtcatca
    28441 tcgggatata ctgttccgtc gatcatgatg gatagcggca tgacacgaat gcctaaagca
    28501 tcgcgtacat ttttttccat cgtacatgaa gaatctgtta cgatttttac atttgtcatt
    28561 attttctctc tctctttctt taacaagatg ccttattcat gttaaactac atgtaagaca
    28621 atttctattt ttagtataac agacaaataa tgatttttca ttaattacac ctagtaaagg
    28681 agccgttttc atggaaaaaa cgaaatttaa tcgaacgtat gaaatattaa atgaagtgtt
    28741 taatgcagtc acccatggaa ttgggactgg attgagtatc gcgggactag tggttctttt
    28801 agtaaaaggt gcccacttgc attcctccct ccatattgtc tcttatgcta tctatggatc
    28861 gatgatgatt cttttatttt taacgtctac tttgtttcat tcattgattt ttacaaaagc
    28921 aaaaaaggtg ttccaagtat tcgatcatag ttcgattttt cttttgattg caggaagtta
    28981 tactcctttt tgtttgctga gtatccgagg atggctaggt tggactttat ttgtattaat
    29041 ctggttgttt gcgattcttg gcattatata taaagcgttg acgttgcata aacgggagag
    29101 agtatcaaaa gtatctacga tcatctatat ttttatgggg tggctctgtg tcgtggctgc
    29161 tgttcctctt tatcactctc ttggaatgac tggtgttatt ttgatggtag caggcgggct
    29221 ttcttacacg ataggcgcat tcttttatag cttgaattct atccgctata tgcatgttgt
    29281 ttggcatttg tttgttatgt taggtgcagg ttttatgtac ttctctgttt tattctttac
    29341 ttaataaaaa aaataaagct atggatggga cagctctaaa taacagctag tctatccata
    29401 gcttttttat atcgtcaatt cgcctgtccc gctttttaca ggattctcat tacgctgata
    29461 cgtttcaaat tgatgcggat aacgattttt ttcatccatt tctccttgac tagtattgat
    29521 cagtgaccaa tcagaccagt caacaggtgg aaaataagca tctccatcga atacatgatg
    29581 gatgactgta cggtataata tcgtacaaaa tggcagaaat tcttgataaa cagctgaccc
    29641 tccagcgatg aaaaagatac cgtctgtttc tttttccaga gcaagcacgt cttccacact
    29701 atgcatgaca tgcacgcctt ctgctttata ggaagaatct ctcgtcaaaa caatcgtctg
    29761 acgattcggc aacggacggc tacccatccc ttcgaatgtt tttcgtccca tcactagtgt
    29821 atttgcttct gtcatttgtt tgaagaattt cagatcattt ggcaaacgcc aaggaagacg
    29881 gtcttctttt ccaatcaatc cgttttcatc ctgtgcccaa attgcagcta acattttctc
    29941 atcctttctg attctaaaca gcgataggag ctttgatcgc cggatgtggg tcatatcctt
    30001 ctaattggat atcttccatc tcaaaatcaa atactgactg cttttcctga ttcaaaacta
    30061 aagtcggaaa tgcgcgtatt tctcggctca attgttcttt catttgttcg atatgattga
    30121 tataaagatg agcatctcct aatgtgtgaa caaattcgcc aaccgctaaa cctgtttcat
    30181 gtgcaattag gtgagtcagc aacgcataac ttgcaatgtt gaacggaacg cctagaaaca
    30241 catccccact gcgttgatac aattggcagc ttagccgtcc ctcttgaaca taaaattgaa
    30301 acatcgtatg acaaggaggc aaagccatgc taggaacatc ttccggattc catgcagaaa
    30361 cgatcaatct tctagaatca ggagtctttt tgattgcttc gatcacttgt ttgatttgat
    30421 cgataaagcc accgtctttt gtttcccagt gacgccattg atagccgtag atgtgtccaa
    30481 gatcgccgta tgtttcagca aaggaatcat cggttaggat cttctcgcaa aaaagcttgc
    30541 tctgcttttt atattcttca ttgaattcag gatctgtcaa acatctatgg ccaaaatcag
    30601 tcatatctgg tccattatag tctggacttt tgatgtagcg ttcaaatgcc cattcatccc
    30661 aaatatggtt tttattttgt aatagatagc ggatattcgt atctcctttt aaaaaccaaa
    30721 gcaattcgct tttgatcaat ccaaaaggta ctcgtttcgt tgttaacaaa ggaaaccctt
    30781 tttgcagatc aaaccgcatt tggtatccga ataagcttaa tgtgcctgtg cctgttctgt
    30841 cttctttacg atgcccttct tccaacaatt ttcttcctaa gtcaagatac gcttgttcca
    30901 tcctttttcc tcctaatctt ctacccattc actcaagtat tcccaccgtg ccattttttc
    30961 ttcaagttgt gcttctgttt cagatacgtc gttttgcaat tcttgtaatc gagtgaaatt
    31021 atctccttga tgattcatct cttcttggag caatgagatt ttttcttcaa gttctgcaat
    31081 ctcatcttca atcgtttccc attctttttg ttccatgtaa gataatttct tcttttcagc
    31141 aggttccttg ctctgtattt ttggtttcgc tttttcagca ggctgctggg tctctttttg
    31201 cttcagtaaa taactggaca tgtttccgta ataaagttct tgttttccgt ttccttggaa
    31261 tactaataac ttatctgcta ccttgtccaa gaaataacgg tcatgggaaa cagtgatcac
    31321 agcacctgga aaacttctaa aataatcttc caaaatcgtc aatgttgcta tgtccaaatc
    31381 attggtcggt tcatccaata ataaaacatt aggttgctga atcagcagtt tcaacaaaaa
    31441 taaccggcgt ttttctccgc ctgaaagttt gcctatcagt gtcccatgca taaatcttgg
    31501 aaataaaaat cgttcaagta attctgctac tccgatttga ctgccatctg ctgtttttgc
    31561 ttcttcagca gcttcttgta agtaagcaat catccgttta tctggtgcca tttcttcatt
    31621 ttcttgtgta taatacgcaa gatgaaccgt ttcaccgata gacattgtac cgctatccag
    31681 gggaattctg ccagctagaa tattaagcaa tgtcgatttt cccgcaccat ttttaccagt
    31741 aatacctagt ctttcccgag attgaatcaa taaatctaaa tgttctagca gtgtttggtc
    31801 atttatacgg taactgccat ctttgatttc cagtactttt ttccctaaac gttgtgtcgc
    31861 taggttcagc tctaaatcat cttcttggtt tacttggtac aagttctcct ttagatcttc
    31921 gaaacggttg atccgtgctt gctgcttggt gccacgtgcc tgtacgccag ccctcatcca
    31981 agctaattcc tgtttataaa gccgcttgcg cttttcttct tgttctactt ctacacgatc
    32041 acgttctgct ttttctaaga cgtaagcttc ataatttcct ttatactcgt ataattttcc
    32101 aaatgaaagt tcgaagattc ggtttgctac tctatctaga aaataacgat cgtgggtaac
    32161 catcaatagt gcgccacggt attgtttcaa atagttttcc aaccactcga tcgcttcata
    32221 atctaaatgg tttgttggtt cgtctagtaa tagtaaatcg ggttcatcaa tcaacacttg
    32281 cgccagacta actcgttttt tctgaccacc tgataaagta ctgatttttt tatctaattc
    32341 actgattcct aatttttgca aaataatctt tgcgttggta tctgtagtcc aagcatcttc
    32401 tttattcatt tgttcttctg ctttagcata acgtttttgc acatcagggt cttctccgtt
    32461 ttcccctagt tcgatcaatg cttcctcata tgctcgaaca gtttggatca aggggctgtt
    32521 tccttgaaag actgcttgga gaacagttaa ttcatcggaa aattcagctg cttgagaaag
    32581 ataaccaata cggtaatcag ttggataaaa cactgtttgc cgatcaccgt cgctgctatc
    32641 gataccggca ataatattta agagacttgt tttacccgtc ccgttcgtcc caatcaaccc
    32701 gatacggtct ttttcgtgga ccaaaaaaga aatctggtca aacaaatctt tttcaccata
    32761 agtttttttg aggtcagtta cttttaattc tttcaacatg ttccctcctt atcttggata
    32821 ttgtatcata aaaatagtga acttcaggaa aatttttttg gtatttgttc tttttgtgtt
    32881 ctcaaaaaaa gaacaggacc gattcgatcc tgttctgata tgttttgttt tttataaaac
    32941 ttgaaaattt ttaccttttt attttattgg actcgttttt tttgactttg ctcgaaacgc
    33001 aaatcggaaa gaaaagttat cagatggttt gttcatcgta taagattcta acaaattgat
    33061 attcctgcga tagctgttcg cagaaaacgt cgtgattttt tcagcaactt cgtattcatc
    33121 aatgattttt ctttcaagat aataacctct tagcattttt ttcgtaaaca gactatcttg
    33181 ctggatcatc cacgaagaaa tcaaattccc cgagttcatt tttattcctt caagtttgcg
    33241 ttgctggata aaaaattgaa ccatcgtttc atcataaata tcagtcaagt tatctaaact
    33301 ttcaataatc aactgagtat ttttttgata tgtctctctg atttcttgga tatcttcatc
    33361 actaataaat gtctgacgat cagcatatct tctttgccaa aacattttcg gatggagaac
    33421 gattcgcatt aacctacgga caacaatgaa ccaaaagccg ataaaagaca aaatctggct
    33481 tgtgatagaa tgttcgaatc gagaaagaaa acgggagtaa aaacgataac cattagaaga
    33541 aagcttgccc gaacgataac tttcatccaa tccatcccgt tcgatcgaca aaatcagtgc
    33601 ttgtatttct tgtacttctt gcttttcatc atcggttaaa tcttccaagt acagatcacg
    33661 tatccgttct tgataatttt ctatcactgc ttcagtggct aaaaattctt ttgtattacg
    33721 atcaatttcc tttatttctt ttcgcaaaac ttcaacgacc tcttctaaaa tcatcaaagc
    33781 attcaaatcc gtgcttttcg cttcctctgt ttccgtcagc ataggcaaga caatgatccc
    33841 tatgaccaaa gtcactaaga tgacacccgc cgtcagaaac aaaagcaaag accgctggta
    33901 aaacatcata ttattgattg aaaatggcaa aataaaaatc gtagccaaac tgactgttcc
    33961 ctttacaccg ccaaatgtta agatcaagat ctcgttcaac tgttttttga actttttact
    34021 gccatctttg aatacataaa aaagactgat agaaatgaat ctgatcacaa aaagcatgac
    34081 agagattaat acgataatcg ctaataaaag accgtttgga tataaaccgt ctccccatac
    34141 tggcgagaac acttgcgtca attcgattcc taaaaatata aatactaatg cattcagtgt
    34201 aaaagcaata gttgtccatg tactgtggga caagctcgac aattctgcat caaacacaga
    34261 gattttccta aaaccagaag cttggagaat acctgctgcc actgcagcaa tgattccaga
    34321 tacatcaaat gcctctgcca atacataggc tagaaaagga agcaaaagtt cgatcagcag
    34381 ataccctgtg acatcttgtg ctgatgcttt ttcgatcaaa tgaattattt tttgtttgaa
    34441 ccagacaagc aaaaagccga tcaaagctcc cccaatacta gaaactacta gactcatccc
    34501 cgcgtttact gctgaaaaag atccggtgat cagcgcacca agagcaaact ggaaggcagt
    34561 aacaccagat gcatcattca aaagaccttc tccttccaaa atatgcatcg cctttttagg
    34621 gatattcact cgtccagaaa gagaactgac tgctaccgca tctgtcggac ctaacgctgc
    34681 tccaaaagca aagcaggcag caagtgggac acttggcaac aggaatgata acgtcgcacc
    34741 taccccgaca agggtcaaaa tgactcctcc aaatgccaag aacaaaattg tcccgaaatt
    34801 tttgagaatc gaagaaatat ctgctttttc tccttctcta aataacaatg gtgcaataat
    34861 cataactaag aacaattcag gttcaaaatc gattgattgt ccccactctg tcagacctaa
    34921 taccactcca aggaaaattt ggatcagtgg agctggaatc attggcaaaa tgcggctagc
    34981 tatgttcgat aaggtgatcg ttactgcaaa tacaataact aactcagcaa attccatcgt
    35041 ccatcccctt tattttttat tttgtgtaag catttttaaa aattgttctt ttttctttaa
    35101 aattttggtt tcgactactt caacctgtgt ttggttcccc tctaattcac actgtacacg
    35161 ttttgactcc aaacgaagca gatcatgttt cagacgttcc aactgacgat acatcaatat
    35221 atttctttta cgcaacttac aaagtatttg acggcggtca tccatcgaaa gggcgccata
    35281 gcgatcatgc aacagttttt tttgttgttc aaaactctct ctcattttcc agatctccta
    35341 tacacaaact tccatcatta tagcaaagtt ctttttggat gaaaaatatt tcattgtttc
    35401 atcgtttatt gctagttaga aatttccata aatttttcaa cgcctcattc tattccaaat
    35461 agtatcagat atcaagtaaa acttaagaaa gataaaagtt tctgacaaaa ggatgtttac
    35521 tttcccattc ctgcctttct tgttctttta tcacaacaaa aaaatggggc tgcgacaaaa
    35581 atcttgtcac agtcccttat tctgaataaa cggtgtggaa gagacagcct atcagtagta
    35641 ataagacaca tctctttcac agcctcattt ttgcgtaaaa atcgatttat tcgaaaaatt
    35701 ccccgtatac atcttctaca cgttgatctg gattgatcac gatatacaag ttacctgttt
    35761 tttcgctgat ttttgttgat tgatattgat tgtctaatcc ttctgttcct ttatctagat
    35821 atgggaagta cacaagatca ggtgtgccat ttcggtaaag gatttccatt cgctcgatat
    35881 cttcgtattt caatgcgcga ttaaacatgc ccatttccag tccgcctagg ttgatatcat
    35941 gtgtcgcaac tgcgtcccct tcatggaaga tttcgatttt aaatccagca cacggatgga
    36001 tttcaacaaa ttcactgcca ttgattcgtc caaaacttgt tgtgatttgt ttgatccaaa
    36061 gatcgccgat atgacggcgg ttgatcgtcc aggtttctcc atttctaaaa taaaatttta
    36121 gcgctgtcat ttctttactc attaaaaaga ctcctttatg atgtaattta ttcttgtact
    36181 acctcagttt agcacaaatt tatgtaagtg gtcacatctt atgttttttc ttctaatgac
    36241 gtatctgccc actttaagta gccaacaaag ctgagcagat acagtctagt gttttttaaa
    36301 tcaatttttc tttcgataaa aaatccaaaa cctgtttttt atcatttttt attctttgtt
    36361 ctacgacggc tttttcagct aattgcaaag cttcactaac ccacttacca ggtttttttc
    36421 cagtttcttc tagcaagatt ttaccatcta ctgctaattc gcttaatgac ttgataggta
    36481 aacgatcata ggattctcct acggcatcca tctgaggtgt ttcgtcaaaa tagatcatca
    36541 attcttctac ttgcagtgca tgttttttgc ctaagaagta caattcgaat ggttccaaag
    36601 ctccagtttc tcgttgtcgt agtccttgga caagtgcttg aacgtcttta atcatttggt
    36661 tagaacactt ccacgatttc aaaaaggaac gaatctcatt ttcttttaga tccagttggc
    36721 tgatcaataa tgcccatgct tggctctctt ctttcaatgg gacggatggt aattcagcaa
    36781 aacgtaaaag tgcttcgcct tcttctttca aaccgggaca gcaaatgtag cactctgttt
    36841 caataaatgc atggattccc gcggcccgtt catttcccaa gagcatcttg atgaattcca
    36901 catttatacg ttctacagat attttaccta atagctcgtg gttttctttg atggcgtaga
    36961 aggtttcttc ctctaatttg aaccctagtt gactgacaaa acgcaacccg cgcatcattc
    37021 gtaaggcatc ttcatggaac cgctcatgag gattgcctac agctcgcaag atctgttctt
    37081 ctagatcttg cagaccatcg aacaaatcga tgatttctcc atcttctttc aaagcaaacg
    37141 cattgatcgt aaaatctctt cttttcaaat cttctgccaa cgaacgaacg aattcgacat
    37201 gatctggtct acggtagtcc tgataagttg attccgtccg aaatgtggtg atctcatatt
    37261 gttcatcatt ttctaatacc aacacagttc catgttcgat cccaatatct atcgtttttg
    37321 gaaaaagctg tttgatttct tctggaaatg cgcttgttgc gatatccaca tcatggattg
    37381 gctggttcag caagatatca cgaacacttc cacctacaaa ataagcttca tatcctgcat
    37441 tctctaattt tttcagaact ggaattgcct tttggtattc cagaggtaat tgttttaatt
    37501 tcatttttcc aacctttcct gcgtgtttct tgtcctgaga taaagactca gttgcatggt
    37561 gactgtttga caagtccgtt tcagagtctt caaggccagg accacttcat cttgtttact
    37621 cgtccttacg ctcaaagcga ttatggtctc tttgattgaa tttttccatg tttttttcaa
    37681 aaacttcagt taagtcgata ttcaatgaat tagccatgat catcgtaacg aataaaacat
    37741 caccaagttc ttctgctacc gagttaactg gttcagaagc ctttttgctt ttttctccat
    37801 aagtgtggtt gacttctctt gccaattcac ctacttcttc agttaatcga gccatctgag
    37861 ctaatggaga gaaatacccc accttgaatt gctggatata ttcatccact tcctgctgca
    37921 tactgtataa agaacgcttt ttatccatct ttttccctcc aaaactatct taccaaaact
    37981 ttaacgcaaa tcctagataa gagcaattga gaaaatcgaa tttccatgct acatttagga
    38041 aggaatttct aaatggaaat tctgtgaaaa tacataattg aaagctggaa ttcatatggt
    38101 caaacgaaaa acagtaaaag aagttctttt tatcattata ggaacaagta tttatgcatt
    38161 tggtcttgtt tacttgaaca tcgctaatca tttagcagaa gggggagtct cagggatcac
    38221 cttgatctta agagctttat ttggtattga tccagcttat acgactttat taatcaacat
    38281 cccattgatt ttactaggag gaaagatcct cggtaaacgt tccttggcct atactgttct
    38341 aggtacactt tctttgtcat tctttttatg gatctggcaa agggttccac tagaaatcaa
    38401 tttacagcat gatctactga tcgtttctct acttgcgggt ttagttgcag gtgtaggaag
    38461 cgggatcgtc taccgcatgg gtggaacaac aggcggcagt gatattatcg ctcggatttt
    38521 agaacaaaat tacggcatca ctatggggcg ttccctattg gcatttgata tcatcgtctt
    38581 acttgcttca ttaacctata tcgacttgaa acgtatgatg tatacgttga ttgtttcgta
    38641 tgttttcagt cgtgtgattg attcgatctt agatggcgga tattctgcaa aaggtctact
    38701 tgtcgtctcc aacaaaagcg aagagattgc accactactg atgaccggtc tgcaaagagg
    38761 tgtgactttc ctttctggag aaggcgcatt ctctggtaat tcaaaaaaaa tcatctatat
    38821 ggtcgttagc tctagtgaat taactgaagc taagaggatc gtccacgaga ttgacgaaaa
    38881 agctttcctt tcaatcatca atgtgcatga agtggaaggg caaggcttta cttatttgaa
    38941 gccacagaca agattactga aaaaactata agaaaaaaga caaagatagg ctatgaggaa
    39001 agattccaca tccagctgac ctttgtcttt tttagtacta tactattttt aactaattgt
    39061 tatgttcact tacccggtta cttttctttt gtgtctgcaa aaggatcttt cggttaactt
    39121 catcagataa tttcaaaaaa gcatccctat ctccatcttc tagtgcttga tcgatttgag
    39181 cataaagcat ttttagtttt gcctcttctt ctttttcttg aaaatatcgt tcaattaatt
    39241 cagtatcttc ttcactgact gaagaatccc aagaagaaaa tggattgtct tctaagatag
    39301 atagatattc tcttgtctgc caagcatttt cgaatataca ttccacatat aaaggctttt
    39361 tccaattcaa acggatttca tgaaaaatct ggtctgtgtc cgtaaattct tttccctgca
    39421 aaaacaattt catgggttcc ccttcaacag atagatcact gatctgcagt cctcgatccg
    39481 caaaattcgc cccttcaaca aagtggacat tgcttaaaat cgcttcatga ttggcaagat
    39541 aattcaagat ccaaaaaact tctcttcggc taaaagatac atgattgacc atccacgtta
    39601 aaaaattctt cttttcccgt acatcaatta gcatttttct cacctctctg ttaggtcatc
    39661 taataatgac agtgcctcca tatctcctgg ttcaagtgtt aaataataag tcaataattc
    39721 ttgcgctctt ttcagctgcc cttcttctct taagaaaaag gcatactctt tcaagaaatc
    39781 tggttcatgt gatagttcat gataagcctg ttcatagtgt acagctgcaa cggtaaagtc
    39841 ttctaattca ttataagcat gggctaggtt ccattctgca taaggattag cagtttcttc
    39901 catctgattg atcacttgta tcacatcttc atatctttca tcatccaagt aaagattact
    39961 taaagtaagt aatgtttcat cttgtttgtc tcctacttct aaagctttca gtaaaagttc
    40021 ttctgctcgc tgtctatcat gcagacggaa agcattttcc gaggccaggt gataaagttc
    40081 gacttggtaa ggattttctt tgattccttc ttctaacact gtttgtgctt cttcaatcat
    40141 ttcttcttct tgaagagctt gtcctagata tagatataac gattgataat gcggattaac
    40201 ttctcgaagt tcttccagat agttgattgc ctgctgattt tctttcaatt gaagattcgt
    40261 aaaagctagc tggaacagtc gatcatctgt cctttcttct ttcagtgctt cttctaaagg
    40321 tacgatagct gcttcgaatt ctccttgcat acttaaggat tgtcctaaac gttcctgcat
    40381 cgagattcct gaaatttcat ttatcccgct tgccaacaat gtttcataaa ccactgctgc
    40441 ctctttgaaa cgatcaactg aaaaatacaa ttcagctagc gcaaactgga tcaatggttc
    40501 atcaggaagc aacccagctg cttctttcaa ttttgcttca ctcacttcag ggattccgat
    40561 aacttggtac aaatcagcta tcgccaataa gctttgcgga tagtaatcac tttgcttatc
    40621 cactttttcc aggtattcaa aagctaagtc gatctcatta tcttcgattg caatttctgc
    40681 taacgggatg ttcagtccgt cattttctgg gtattggttg atcagttgtt caaaaatctg
    40741 ttttgcttcg atcaaaaagc caatagccag caattcttcg cctagttcag ctaatatatc
    40801 tgctgggtct tcttttaatg ctttttctaa aaagatttgt gcttgtgaca agtcttcatc
    40861 tgataaagct tgcaacattt tttcgctatt tgtattcatt tcaattccct cttatctcac
    40921 tgacgatttg ttgaaatacc gtcattgttc tcaataattc tttttcgttt ggatgttggt
    40981 atccgtctat tatacctatt ttttctaaaa caagtatttt tttgcttttt tctgccaaaa
    41041 aaagaacttt ttccaaatac tccatctttg aaatctgttc cagccagtgg attggatagc
    41101 caagcaagtc cagccacaca aaaaagtttt ttagttggaa atcaaaagga tatgcttgga
    41161 gattccacac gaaatgaaac atcattccta aaaatttttt catactagca gaaagtagat
    41221 ggccattttc ggtcagataa aaagcttgtt caaacagttt accataattt gacaggtttt
    41281 ctgcctctaa ttgataaaaa tagatcattt cttcgatcat cccggcaaac ggccgagtcg
    41341 ttaattgctt tttatttgga tagtttttat acagattttg caaaaaacga tgatcacaaa
    41401 tcattccgca acagataaaa gtcaaaaagt caatctgctt tccgtccacc tgccgctcgc
    41461 tgattgtttg atcataaacg atgcgttctg gcagattgat ggtttgcagc actacacgat
    41521 ttggtagctg caaaatcgtc cgctgcggtg ttaatgctcg gcttagagaa cggatcgata
    41581 cagggatcat ccatagtgat gaatcaaggg ttgtatgttt ttgaaaaaaa cctgccagat
    41641 ccatgatccc ttcatttcca aatccgatga taaacatgga ttgattttcg ggatagcgtt
    41701 tgacgaaatc aagcaggttc tttaattctg ttaaatgatt gcattgagtg ttggcacaaa
    41761 tataccagtc attgtttgct tgatttgcaa ataacgggtt gatcttatct gcaaacaaat
    41821 cataatagcg ctgattcgtt aaaaataaga ttggctgatc aatggaaagt tctcttagct
    41881 gactgactag cgtttctccg taaaacactt tcgtcaacgc atcttctact tgataatcaa
    41941 gttccatacg catccctcct cttcttattt ttattttacc attagtaagc aaattctaga
    42001 aaagataaga gcaaagctca cctcataact tgcaaataaa taaaaattaa ataaaataca
    42061 tgtgttttct atgtatgaca tacggattcg gaatctctgt ctcttattta ttccttttct
    42121 gctaggaaat aaaaagaaaa gcacttgtag ccctagagcc acaagcgctt tttcaactgt
    42181 cttatttaac agcgtctttt aatgctttac ctggtttgaa tgcaggtact ttgctagctg
    42241 gaatttcgat ttcttcacca gtttgtgggt tacgaccttt gcgagctgcg cgttcgcgaa
    42301 cttcaaagtt accaaaaccg attaattgaa ctttttcgcc gttagctaaa gcatcttgaa
    42361 tagttgaaaa tacagcatct actgctgcag ttgcatcttt tttagttaaa tcagtagctg
    42421 aagcaacttt ttcgattaat tctgctttgt ttgccatgga tagattcacc tcctccacaa
    42481 gagatatgat agaaatatca tttagttaaa actttctgag tggtccagaa gtttaaaaag
    42541 aaatattgat taacttcaat attctgttat cacgatatca tatgaaccgc ttaatagcaa
    42601 ggtttttacc aattttcaca tgcttttttt agtcatagaa acgtaacaaa cgaaactgtc
    42661 tttttctttt gaaaaaaaaa cgtcgatatg gtaaaatgcc tattttctcc tacgagggat
    42721 aattcggatg gacgtccctt caaaagtaaa tgcttttctg atttgatttt ctaagaaacg
    42781 ttcataagaa aaatgcatca attcctcttc attgacaaaa acgacaaatg taggtggttt
    42841 gacagcgact tgtgtagcat aaaaaatctt caggcgtttt cctttatctg ttggtgttgg
    42901 attgattgct acagcatcca taatgatatc attcaacaca gccgaagaga tacgaagatt
    42961 ctggttcata cttacttgtt cgatcatttc aggcagacgt tccaaccgtt gtttagtcac
    43021 tgcagaaaca aaaacgattg gagcgtaatc aagataccgg aattcatcac gaatctcttg
    43081 ttcgaaatca cgcattgtat tggtttcttt ctttacaaga tcccatttat tcacgacgat
    43141 aataattcca cgaccagctt catgggcgta acccgctact cgcttgtctt gttcccgaat
    43201 cccttcttca gcattcagta ccatcaaaac gatatcagaa cggtcaatgg cacgcattgc
    43261 acgcatcacg ctgtattttt cagtattttc gtatactttt ccgcgtttac gcataccagc
    43321 tgtatctatc attaagaatt tctgaccact ttcagaaacg aagtgggtgt cgattgcgtc
    43381 tcgggtcgtt ccttcaatat ccgaaacaat tacacgttct tctcctaaaa tcgcattgat
    43441 caaagaggat ttaccaacat ttgggcgacc aatcaaacta aacttaatcg tgtcgtcgtc
    43501 ctcttcttca gtctcttcag agaaatactt cactgcttca tctaaaatat caccaatccc
    43561 tagtccatgg cttcctgaaa caggataagg atcgcctagc cctaaggaat aaaattcata
    43621 gatatcgttt ctcatttctg gattatctac tttattgact gctaaaatca ctggtttatt
    43681 acttctgtat aaaattttcg caaccatctc atctgcgtct gtcacgcctt cgcgtccgct
    43741 gactacacaa atgattacat ctgcttcttc aatcgcgatt tctgcttgat gcttgatctg
    43801 atccataaaa ggttcatcgc caagatcaat tccgcctgtg tcgatcacgc tgaattctcg
    43861 acctaaccat tcaccttttg cataaatacg atcacgagtt actccaggag tatcttcgac
    43921 aatcgagata cgctcaccag cgatgcggtt aaaaatcgta gacttaccga cgttcgggcg
    43981 gccaacgatt gcaattgttg gatttgccat attatttcct cctcacaagt ttccaatctc
    44041 acttagttta acgaatgcat tgccaacttt caagcataga ttgtcaatta aacgaagtat
    44101 ttttattcct tattgaaata ctaatcgctt ttcaaaagaa aaactgagac aaaagcagct
    44161 gctttcatct cagtcacaga tacaaaatca attatttttc agaatcatcg gttgcttttt
    44221 cttctacttc ttctttcaac gcatcaccta aaatgtctcc catagtaaat ccagtatttt
    44281 cttctggtaa ttcataagac tcaacatttt ttggttcttc ttctgaagct ggtttttctt
    44341 ctaaagcttt gatactcaat gcaatacgat gttcttctgg atggatctct aatactttca
    44401 ctttcacttc gtcaccttca tgaagcactt catgtggtgt cgcaatatgt ttatgtgaaa
    44461 tttgagagat atggactagc ccttctactc cagggaacac ttcaacaaag gcaccgaagc
    44521 ttgtcaaacg tttaactgtt ccgtctaata ctgtgccaac tggagctttt gtatcgattt
    44581 ctgaccaagg tccaggctgt gtgtctttga ttgacaagga aacacgttct tgttcaggat
    44641 tgatagacaa cactttgaca tttacatcat cattgacagc caatacatca cttggttttg
    44701 ctacatgact atgtgaaatc tctgagacat ggactagacc gtcaattccg cctaggtcga
    44761 caaatgcgcc aaaatcagta agacgtgcaa cacgtccact gagaacatct ccctcatgga
    44821 tagttgaaag aatttctttt ttcttttctt ctctttcgtt ttccactacc gctttatgcg
    44881 ataagatcaa acgattttct gatggttcga tttcgatgat tttaaagctc aatgttttgc
    44941 ctttatagtc tgaaaagtct gcaacaaaat gatcttccac cattgatgca gggacaaaac
    45001 cacgtacacc gacgtcaacg actaaaccgc ctttgacaac atttgtaaca ggtgcttcga
    45061 tgaccttgcc ctcttggaaa tctctttcga tatcttccca aactttttta gcatctaaac
    45121 ggcgttttga aagtagatag ctgccgtttt ctttatcttt gccgatcgta ctgataacga
    45181 ctaaatctaa tacatcaccg acttttacta cttcgctgat atcttctacc ggcaaagttg
    45241 ataattcttt tgccggaacg actccttcaa ctccagcccc ttcgattccg acaatcactt
    45301 gtttgtcttc aatgactaaa acttcgccct taacaacatc gccaactttt acttcttgta
    45361 cgcttttcat tgcgtcttcc attgactggt tgttctcttg attttgatca aattctgtca
    45421 taacacttgt cctcctaacc aacattctgc cgtaagtacg gtactgtttt tagtttaatt
    45481 gattattcaa aaaaaataaa gcgatttcgt tcgttttcct tgaaaaaaca attgtttttc
    45541 attttttttc ttaatttaaa aaagaagata accttttttc aaaacaacag cttttattgc
    45601 tgcaacgact tctggaatcg atttgccagt cgtatcgata cgaacagcat cctctgcttg
    45661 cttcagcgga gagacgtccc ttgttgaatc ataatggtct ctttcctgta tctctttcgt
    45721 cagtgtttca agatcagtcg gaattccttt ttcttggttc tctttgaaac gtctttctgc
    45781 acgctcactt acgcttgcta ctaaaaagat tttcacttct gcattcggta atacagctgt
    45841 cccgatgtct cttccgtcca tgacaacgcc accgcgttcc cctatttttc gttggacagc
    45901 aactaattct tctctgactt ttccatgtgc agagacttca gaaacagctt ttgtgacatc
    45961 tggttgacgg atttctaaag tcacatcttt tgatgctatg aatacatgct gtccatcttc
    46021 ttgttgcgaa aaagagatag gatacttttt gatcagcgaa actagccctt cttcatctga
    46081 aaaagataca ttgttcgtaa tagctaaata agttactgcg cgatacatgg caccggtatc
    46141 tgtataaata taattcaatt cttttgctaa tatcttggca acggtacttt tcccagatga
    46201 agcaggcccg tcgattgcaa tactgatttg tgtcatgata taactccttt ttctcagaaa
    46261 aaaagccgca aagcgcggct attattattt aattcttaat tcttgaccag ggtaaagcat
    46321 aaagttgttt ggatctaagc cattcaattc aaacaattga tcagtggtga tccctgcacg
    46381 ctcagccact tgttttggac cttcgcctgc ttgaacagtc gttgttgaac cggctgcagc
    46441 tgatgaagaa ggtgttgttt ctgctgcatt gctgcttgaa tcccctgctt gataagttgc
    46501 ctcacttgag gaagtcggtg ttgtctctgc tgcaatactg ctttctgacg ttacacctgt
    46561 atcttgagac acagtagatt cttccgcgat tgtactagat tctactgttg aagtctcagt
    46621 tgactcctct tttgttgtac ttgtagaact ttctactact gatgtcgaag tttcagaaga
    46681 agttgctgct gttgcattgt tgcttgatcc atttctgatc cagaaataag cacctgctgg
    46741 aatagcgata cataagacca gtaaaatcaa aaatagcgaa agaaataatg tatttccttt
    46801 cttttgttgt ctctgagaac ttcttgatga aacttcatca tctgtatcgt agattggttg
    46861 ttcccatggt tcttgtgttt cgttattttc tgtagattga tgtctatctt ttctgctcac
    46921 tgttttacct cctaaactct atcgtgtgta ttataccata ggaaaaagtg tcttgtccta
    46981 aaaaatcaat gttccatgtt ttttttaaat aaatttagta aaatcgttcc ccaatgaagt
    47041 tgttcagtct tagaaaaaag cttcctcttt ggcagaagtt ctgcttttgc tccatcaata
    47101 tcacaacaat tctgcggctt ttcggagagt ttttcgccaa aataagctaa gatgaatttt
    47161 ctgcggcagt tttcttcatt aatatagcga agcatctgct gcaggcggaa ttctttttct
    47221 ttttcctgac gtttgagccg ttccacccaa ttttctggtt tttcagactg ctggatcagc
    47281 tccatccatt ttttttgcag ctcatcaaag ggagcttgct ctgtggcata ttccaaataa
    47341 agctcaaaac tttgtcgctg ttctctagaa agttgattaa agaaataatg gatacgttca
    47401 tccccacttt gataaaaaag aattgctgca ctttcttcct gatctctgcc tgctcgaccg
    47461 atttcttgta catagttttc tagactgtct ggcaaatcat aatggaccac ataacggata
    47521 tcagatttat cgatccccat accaaatgca ttcgtagcaa tgagaaactg cagctgattt
    47581 tttacaaact gctgttgaag ttgtcttctt tgagctgcat caagaccacc gtgatagtat
    47641 ccaactgtaa aacgttccct gaataaatga tacaatcgtt cgacttcttt ttttgttgca
    47701 caataaatga ttgccgctcc ttgtgctctt tccatgaagt gttcaagttc ttgttctttt
    47761 tgctgcgttt tccgaacaaa aagcgagata ttttgccgat tgactgattg tctgatctct
    47821 tttggtggtc gatcaaatag tacatgacgt atatctcttg ctactaaatc tgttgctgtc
    47881 gccgttagtg ccagtgtgac cgggtttcct aaaagctttc ggatttttcc taactgttga
    47941 tattctggac ggaaatcaac tccccattga gacacgcaat gagcctcatc tactacatat
    48001 aacgcaatat tttgtttttt cagatgctct aaaagagaag gattagtcaa catttcggga
    48061 ctcaaaaaca aaaatttata ttgcgataga tgacggagga cgtatcttct ttcagattgc
    48121 gaaagtaaac tattgaaagc agctactcgt ttctcccctc gtttttgtaa ttgcgtcact
    48181 tgatcttcca ttagagaaag cagcggtgac acgatgatga ccagaccttc cattaaatac
    48241 cccgtcaatt gatagcaaag gctttttccc gttcctgtag gcaaaatagc gagagtatct
    48301 tctccatcaa gcaacgcctg aataatttct tcttggccgg gacgaaatga atcaaatcca
    48361 aaatattttt ttaattcatt tattaacatt ctgtatcgct tcctttctca atagatagat
    48421 ttgatacaaa cgaaattctc cataatctaa ttgtccatct acattccatt cgctaaagcg
    48481 ccactctcgc acggaatcct tatttggttc caaacgttcg attgtttctg cagagagaat
    48541 ccactcgtat ggaaaatcat caaaaaacaa ggcccactca ataagatgat ctgttactgt
    48601 tcctcttttt aaatgacgga ttgccatgat ctggtcaatt gtctgaccat tcataaacat
    48661 ctgcttggtg atcatcatgc tttgattgaa attttgctgt aataatgaat cgatcaaagc
    48721 gtgccaaagc gaatctggcc gtttttcgat ttgtgctaac aaaaggtgga tacatctgct
    48781 ttgttgcaga taaaccgctg actcatcatt gttttttgcc agctgataag gaagcagccc
    48841 tgttcgctca tttccagata attggttagc taaaaaatct gctgcttctt ctggtatctc
    48901 cgaaaacagc tgcaccaaac tctcatacgc agtatcaatc aaaatttcac gtggcaattg
    48961 gctttcacta agccattttt ttagttggaa agtataaaaa ggacttgtct ctgctggaag
    49021 atagtcttga atacccgttg ccagattaga aattacttga acagcaaatt taatgagccg
    49081 ccaactagtt tcccctgttc tgccatagcg gtcaaaacgc aaaccagtat gttctatttg
    49141 atgttcggac aacatatcag cccctgcagg cgttagcttt gcttcatttt catttatttc
    49201 gatccaacct tgctgcgcaa ttttttgcaa aatttgataa aacttatcct gcttcaattc
    49261 tggaaaactg ttatggataa acaaaagttc gtgggtaaat ccataaataa gtactgaagt
    49321 cgttcgtttt cccacaagga gttggtaaag agaactaatc cgcagcttgt gtcctgatga
    49381 aaatagcgat aaaataaaaa caatcatatt attctcctta agttaggatg gttagaaatg
    49441 tcactactat gtaaacttgt acctgaacgc tgtattgcat gcggtctttg tcaaatcgaa
    49501 gcgccagata ttttcgatta tgatgaagaa ggaatcgttt tatttgccca agaaccagag
    49561 gctcatcaac agttcgtgat gccggaagaa gaaacatatg taaaaaaagc gtatcaaaaa
    49621 tgtccagttc gagcgatttt attagaaaat aaaatataaa tataaacgaa actttaaaaa
    49681 cgtacactaa gttctctaaa cttgaaaata agccgggatc tgtttctctt gttccgtgaa
    49741 atcccgactt attttgaaag attcatttgc tatctatagt taattgacta gttttttcac
    49801 ggaccctata ggacccattt atattatttc aactttttca gccagttttc caatgtattg
    49861 acgatcacag tttgctggtc tgcgttagaa atttctgcct ctccatctcc tttttgctca
    49921 ccatagctgc caaaacctcc atgatttccg ccattgattg atacatactc tgttctttcc
    49981 ggtaaatact gcttagcttc ttgataagct tcctgattca atactttatc ttttgtcgcc
    50041 gtgatcgata aaacaggaac agctgattct gtcaatgttc cttttttgtc gggataactt
    50101 gccatgaaga ataccccttt taaatgtttg tctgaatgat tcttattgac ataacgactt
    50161 gccattacgc cacctaatga atggccaccg atcacataat cggaatttgg aaaatcttct
    50221 ttgaccttat ccgctttgtt tccgcccatc actgctagat caagtggcat tttgacaata
    50281 gcgactgaaa agccgttttt tgctaaatct tgcgcccaaa tactataact ttctggctct
    50341 acgagagcac caggataaaa aataagtaat ggagactttc catgattctt tttctctcct
    50401 tcaaaaaata agtaatcttc tttgtttttt ccttctttta ccaacacttg cgcttctgac
    50461 gatggttcgt acgtattttg ctgtatatag taataaccgg ctccaccgag taatcctaaa
    50521 atgatgacta agccaattag tattcgtcta aatattttca ctttctccca ccttttctat
    50581 ctgagtgacc cctttttctt aatcaagtat gattatacct taaaaaaata agagagaaat
    50641 gcaaactttc cagcatcaaa taaaaaaaga cggaatatcc atttgaatat ccgccctttt
    50701 tgtatgttta tttttattta gcacataaac gatacacagc ttctgcataa atttccattg
    50761 ctttatacat actacttaat tcccatcgtt cattcgcctg gtgcataaag tcaggagtat
    50821 cagggaacat cgcaccgaat gccacacact ggttcatcgt acgagcaaaa gtagcgccgc
    50881 ctgatacaaa cggttcagtc atgtctccag taatatcgcg atatgtcccc aatagatttt
    50941 tcactaactc actgtctagt ggcacgtata atgaatcaag gaagtcaaat tcttcataag
    51001 tcaacccata tttttctgct gttttagtta atttagctac taaatcatct ttcttgaatg
    51061 taacagggat tctcatatct acaccgattt ttgtttgttc tggtgtgatt tccaaacttg
    51121 caaagttcat cgttagctcg ccggattgtt catcttctgt tttgcccacg acagcttcac
    51181 cagttgcatt ttcttgaact aattttccta agaaattgat tgggccaaaa tcaaatactt
    51241 ctgaaagagc aattgccaga cgagaaatag cattcactcc ttgtgctgca tctttcgcgt
    51301 ggatactttt accaagaacg acgatgcctt caccttgttc ttcgaaatcg aattcgtgtt
    51361 ttttcaatgc ttcttttact tcagaaagct tttctccaga gtaaggagct gcatcaggaa
    51421 caacattcaa cgctcctcca gcttttacag aaaactcgtt cgttcctggt cctgtcaagt
    51481 aagcttgcaa taagcctttt tctgcataaa ttaaaggaaa ttcagcatct ggcgcaaatc
    51541 cttgcgtaat tccttcttct ttttcgttat atttttctaa acaacgccat aaattttctt
    51601 catctgtacc aaagataaaa cgaatacgtg tcttgaattc cacgccagca tcaatcaaag
    51661 ctttgacggc atacattgcc gcaatagaag gacctttgtc atcttgggat ccgcgaccaa
    51721 ctaaccagcc gtcttttata gttggatcga atggttttgt ttcccaatta ttttcgtccc
    51781 ctgctggaac aacgtccata tgacacaaga taccgaataa ttcatctcca gagccaatct
    51841 ctgaataacc gtaatagcct tctggatctt taaatgttct aaatcctagc ttttcactga
    51901 tttccaatac tttatccaaa gcttcaatca cttttttacc gaagggatgt ccttgtcctg
    51961 aatctgcttc atctagtacg gaaggaattc ggatcaattc gctcaatgat tctaatgctt
    52021 gttcatgatg ttgttctgtc acaaattttt tcatgatatt atcctcctaa tatgttaaaa
    52081 agggtcatgt caaattcctc cgacacaacc tcttcttctc aaataatgac gttttaagcc
    52141 tgctccatca gcaagcagaa tgttcttaac aaatgatgaa agaaaaaaca ctcactgaat
    52201 ggagctattg acttatccac gtgcttatcg atagccgttt atcggtttct tcattcttat
    52261 gatagacctt gtacctgtat ttgtctaggt ttagaacatt gctgctacac ctaggatcac
    52321 acagatggct acaaataata tcgcaattaa tttaccggta aatttccacc acactgaaac
    52381 atcgaaacga gcaattgcta cagcacccat tacgatagca gatgttggtg taattaagtt
    52441 tactaaacca gatgcagatt gataagcagt gattactaaa tccttaccga cgccggcaaa
    52501 ttcacccata ggtcccatga ttcccattgt tgcagcagct aagccggaag ttgaaggaat
    52561 caagaatgac atagggatat agaaaataaa tgtaataatg atgaatacac ttgaagataa
    52621 tgaacttaat ccttgttcgc cccaatgtaa gatggtgtct gtgattaatc cattgttcat
    52681 aaccacttgg ataccacgag caacagctac tacgattgct acaccgatca aatcagaagc
    52741 accagctaaa aattcagaga caaattcaga ctctttcatg ccataagtga ttgctactac
    52801 gatggacatt actaagaata acatagtaat ttctgggaag taccagtcac ctaatggaag
    52861 catgctttta cctagaaccg tacctagtac cggaaggttt gttaaccagt ttgtcaatga
    52921 ttcaaaaatc gtgaaattcg cattcaaggt tgtccaagga atcaaactga tgatcatgat
    52981 accaaaagta ataaagaaca atacattaac atgtttttgt tttttcgtga ttacttcttg
    53041 acgaccgatt gcttcaatat cgaaatgctt catatcttct ttacgttggt tgtatactaa
    53101 tgattttgtt ggatcttttt cgatctttga tgcataacga tacacatata caatagaaat
    53161 agctaacaaa ataacgaaca tcaagaatcg aagaccaata ccttcaccca tcgaaatccc
    53221 aacagcttgt gaagctacgc ctgttgcaaa aggatttacc gttgaagcta gacagcctac
    53281 ttgagaccct actaatacga ttgctacagc tactactgta tcaaagccta cagccatcat
    53341 gactgggatc agtaaagcat agaatggaat cgtttcttct gccattccgt aagtagagcc
    53401 gcctaatgca aataacagca tcaatactgg aataagcatt ttttcttttc ctttgaattt
    53461 cttcacaact gaagcaatcc cggcatctag tgcccctgtt ttgttgataa tacctaaaaa
    53521 tccaccaaca accaaaatga agaaagagat tgggattgca gcaggtgttt ctttagttag
    53581 ctcccccgct ggtacaccta gcatcccatt gattggcgcc atgaaaatat cccacagccc
    53641 ttgaggattt tgttgtactc gttcatatga tccagcgacg atgttgcctg catcgtctac
    53701 actatagtgc ccagctggta taaaccaagt aagtacagcg attactgcaa taataataaa
    53761 taagaccgta tacgctgaag gcatttgaaa ttttttcttt tttgtttgtt ccatcttctt
    53821 cttcctttct tttccgttag agacaacaat tttggctcta atgttatttt atcaaaaaga
    53881 gtatcagaac aaaaataata acacgcattt tgtaaaactt ttgttcaaaa agttcgtttt
    53941 tccctattcc ctcctctttt ttcaggtttt taaagctttc ttctttttca ttgtagcgtt
    54001 tccttttttt tataaacaaa cattttcgtc ttttaaaagg agaagaattt cacatttgca
    54061 aagaattgat tgatttttat gcataaatca aaaaaatact caaaacaaac aaataaaacg
    54121 tttacattat tgcatgtctt gtattttttt ccaaaaaaaa agaccaagaa atttcttgat
    54181 ctttttgata tttatttgac tgctgtatga cgttgttcga actgatgttg ttttcgactt
    54241 aaccatggaa gaagttgcgc atgcagcact aaaaagacag cactcacgat gaatcctttg
    54301 atcaagttga aaggaacgat cccaatcagt acatagtttg ctaaagacat gcccagcatc
    54361 tgtgttgcgt tcagccctaa aaacattaag taaagaggcg taataacgaa ataatttgcg
    54421 atactcataa aaatagttag agcgatggtt cctgtaatga cacctaaaaa tttgtttctt
    54481 cctttatgct gtttctttac actaaagaaa taataaatcg ggaatgtaaa gatcgttgtt
    54541 gataagaaac tagcagtgtc tcctaccaaa ttatccggag aaaaacctgt agtcagcaga
    54601 tgtaatactg aacgcaagaa cgctgttgca actccggccg ctggaccgaa taagaacatg
    54661 ctgatcaata ccgagatatc actaaaatcg atcttcaaaa aactaaaagc cggcatgatc
    54721 ggaaaagcaa aatactgtaa aactaatgcg atcgcagcaa acatcgctac tgcaaccatt
    54781 ttctgtacac gggtgttctt catttgaaat cctcctgtta ggactcctct tcagcgaact
    54841 ttttgacgtt tctctccaaa tgaaaaaact ctattttcca gggaaaatag agttagagtt
    54901 atttgatcaa gcgtcgtcaa ataagctcta tcttctttat ccagactata ctgtcggtat
    54961 cggaatttca ccgattcagc tatttttttg caaaataggt cgtggactat aaccaccggt
    55021 cgggaatttc accctgcccc tgaagacgaa ccttatataa tttttgttta catattcatt
    55081 atacatatct attcaaaaaa cgcaacatct aacacttata aaaagtaagt gttcattttg
    55141 agtggttcag caaactgctg acttcttttt tgttcagttc acggtaatcc ccaggacgta
    55201 ggccttgtaa agtcagatct ccgtattttt cacgttttag tttttgcaca ggaagaccaa
    55261 ctgcttgaag catatttttc acttgatgat tacgtccttc gtggatcgtc aattccacga
    55321 tactgtggtt tgtcttagga tccactgata aaatttggaa tttagctgga gatgtttttc
    55381 gtccttcgat ctttattcct tttgtcaaag gtgcaagcat cgattttgta gcgatccctt
    55441 ttacctttgc aacgtaaact ttatccactt catgttttgg atgtgtcagg cgctgagcaa
    55501 aatctccatc atttgtcagt agcaagatcc ccgaagtatc gtaatccagt cgacctacag
    55561 gatagatacg ttcttttacc atcggcaaaa gatccgtaac aacttttctt cctttgtcat
    55621 ctgcaacagc agaaataact cctttaggtt tgtacaataa atagtaaccg tattcttctt
    55681 gataaattgg gacttcatcc acttccacag tgtcatgttt cccaactttt atccctaatt
    55741 cccttacaac ttgtccgttt acttttacac gtcctgcaag gatgaattct tctgcttttc
    55801 gacgagaagt gatgccagcg tgggcaatta ctttctgcaa tctctccatt acaattattc
    55861 tcctttattc attccatcaa agaatagatc tggtgacacg tcttcttcaa gtgaaatttc
    55921 catttcttgt gtatcaggca gttcttctaa tgatttcaaa ccaaaataat ctaagaagta
    55981 gccagttgtt ccatataata tcggccgacc tggtccttct actctacctt tttcttcaat
    56041 cagtttatgg gcagctagac gctgtaccgc tcctgaaacc tgaactcctc gaatctgctc
    56101 gatttcagct cttgtgattg gctgtttata agcgatgatt gctaaggttt cgacggcggc
    56161 ttgagataat gtgtttgatg tcccttgcgc atatcgctta agtaagggag ccagctcttt
    56221 tttagtcgtt aatacataat ggctttccgt ttcaaaaata tgcaaagctg agtgcgagtt
    56281 ttgagtgtaa gattctttta attctttcac taaacttgtg acttctgctt cgctgagatt
    56341 taacagtccg cttaattctt cattactgat cccttcctcg ccaacaataa aaagaagggc
    56401 ttcaagttca cttaatttcg tcatgttcgg tatctcctac tgctggataa agcataattg
    56461 attcatagtt ttctttttgt tgcgcaatga tctgcccttt tttcatcaat tctagcaaag
    56521 ccataaaagt agtgacaact tcacttttag aaggtgactc aaaaaaagaa tcgaaagtac
    56581 agccatgcgc atttcttttt atacgctctt cgataaatac cattcgttct tcgatcgttg
    56641 tgtcatcggg cgtgatcgtt ttttccactt tttgagaaaa tttcttacgt tctaagattt
    56701 tctgcatggc acggatcaaa tcgatttttt tgacttgtcc tcgcttcaac ggcttttcag
    56761 catccgctaa cccatcgatg ttcataggtt cttttgtgta ataaagactt cgttcctctg
    56821 ctttttctgt cagtctttca gctgcatatt tatatttacg gtattctaaa agctgagtga
    56881 ccaattcttc tcgaggatct tcttcccata attcttcatc gtctgtgacg aattcttgga
    56941 caggaagcaa tgtcttgctt ttgattgcca tcaatgtagc agccatcact aagtattctc
    57001 ctgcaacagc tagctcgagt gttttcattg tatggatata attcatatat tgctccgtga
    57061 tcgtagcgat cggtatatca tatatatcga tttccatttg ctgaatcaga tgaagcagca
    57121 gatcgagagg accctcgaat acatctaatt taatattgat ctccgtcaac tcattcactc
    57181 tttcttcttt ttctttgcta gccattttcc aatgtaaggc tctgtgattt cagttgcacg
    57241 gatggagaca tccgggtact tttcctgtaa ttcatctaac atttgaaagc ccatattctc
    57301 accgcgataa gacggattca aagaaatgtc atggatgatc agctgatcgt tcgttgccca
    57361 gtaaatacca ataatccctt gaatgttggt tgaaccttct ggcgtaaaga aaaaaagttc
    57421 ataatcgtct tcagattcgt acgtatcaat ctccttcaac aaagaagttt tacctgtcag
    57481 tttcttatgg aaactcaata gtcccatagc aattttacgg ttttctttcc ggtaatgtgt
    57541 taacatcttc tcaccttcct atgactaagc ccttggaaaa tgctgcttat aaacatccgt
    57601 cattcttttc ttcgtgatat gtgtataaat ctgagtcgta gagatatccg cgtgacctaa
    57661 caattcctgt actgtccgca aatcagctcc attttctagc agatgtgtgg caaagctatg
    57721 ccgcagcgta tgtggtgtta cttctttgta aatcccagcc tctcgtacta actgcttcag
    57781 atttttccag attccttgcc gagaaagacc tttcccatga ttattgacaa atacatgcat
    57841 ttcagatgcg tcctttacaa gtaatggacg tgcttcgtct aagtagcgtt ccagccattg
    57901 gatcgcataa tcacctaaag gaatgatccg ctctttatct ccttttccaa ctgtctgtac
    57961 cagtccaaga gaaagatgaa gatctcccaa tttcaatcca atcaattcac tgacgcgcat
    58021 cccagtagca tacatgactt ccaagattgc acgatctctt atccctaacg tttttgtcgt
    58081 atcaggtgct tcaatcagct tttctacttc tgtcagagtc aatgtacttg gtaatttctg
    58141 tgctttcttc ggcgtatcga tatgttgcat cggatcatga tcagtgatac gctcttgccg
    58201 taaaaactga tggaatcttc tgagacttga gatcatccga gtaacagttg ctgtcgcttt
    58261 tttttcttca tgcaacttct ccagaaaacg gatgactaaa aagcgatcga catcctgcca
    58321 tgaagcaatt ttctgctcct gtagaaaatg caagtactgt tccaaatcac gttcatagct
    58381 ttgtcgtgta ttggcggaca atccccgttc aatattcaag tagtggagat aatcgttgat
    58441 ttgctctttc ataataatcc ccctcatgcc tctctatcat atcagatacc gcttcattct
    58501 gatagtcttt ttccataatc tgagcaaaga aaaagccgtc tagacactca gacggactgg
    58561 tttctttttt ctttttcata gcattcctga cagattccat ggaacgttag ccgatgatct
    58621 tttactaaaa aatgataacg ttcttctact acttgctcca cttcaagtaa aagatcctct
    58681 tctacttcct cgatcgtgcc gcagttcaag catagtaaat gatgatggaa atgtttggcg
    58741 ccttcttttc tcaaatcata acgggctaat ccatcattaa aacttacttt atcgacaatt
    58801 ttcaattctg tcaagatttc aagggttcga taaacagtag caagtccaat ttccggactc
    58861 ttttttttca ctaaaaagaa gatttcttct gcagataaat gctctttctc attttccaaa
    58921 agcacaagca gagtagcttc tctttgcggt gtcagcttaa accccgcttc atgtagctgc
    58981 tgttttgttt ttttcatcgc cgaaatagca ttcatgacca tttactcaac cccaacaatt
    59041 tataataatt acaaataaaa aaagatataa cactatgtta attaaaatta ttataagcta
    59101 gttaagaaaa acatgcaagg gattctcaat tagatttttt gactagtttt gtcacaccgt
    59161 tttcttgtgt aatcaatcct tgtttcaaaa gattacctaa tgcgcgctta aatgctcctt
    59221 tgctgatacc aaaagctttc atgatttctt ctggatccga tttatctgta aagttgattt
    59281 gctgatctgc agaacgttct aaaatggtta aaatcatttg tgcatcatct gatatagctt
    59341 catatgctct tggcttcaat gaaagattca gtacaccgtc tggtcggaca ccaatcactc
    59401 gaccttttat ctgctcgcct agacgaggtt cattatatcg ttcagaagga tggataaacc
    59461 caagatagaa atcttccgtt aaaacgtacg tacctgttaa tttcaagcgg tatgctgttc
    59521 ctatcacatc tttgtttttc atttcttctg ttccatattt gcttaaagat ttgaatattt
    59581 tttcatctgc taaactgccc caaatacggt cttttgcatc aactctaagg gaaatcatca
    59641 agcgatcccc ttttttaggc catagctctg tcattgtcgg caattcatca agagatacga
    59701 caaagtcttt atctggaaga ccgatatcga caaacgcacc taaatctttt cgtgtagcag
    59761 taacgattcc aaaagcgtaa tgaccgatac ggcttttagg aatttgtgta gtgatccgat
    59821 tttcatgttt ttgattttgg taaccgaatc cttcaactgc ttcaccgatt ttgtgttcac
    59881 cttctgattt gcttaagcca aaggtttgtc cgtttttttg gacaaagtag tttttttcat
    59941 tttcatcaat aataatacct gtaaatatag ttgctaataa atcgttcatt tttttctccc
    60001 tctatagtga aaggttttct taatacattt ctttgctatc ataacataat gttatctact
    60061 tgaatagctg agccttggtt tggaaaggtg aaaaaaggag tatgacaaca gttgtgtcat
    60121 actccccttt ttcgaataaa cggtgttaaa cggcaggctc acagcctctt tcatttgcct
    60181 aaaattaatt gctcccattt cctccgaacc atccagtttt acagttgatg gttacgatgt
    60241 aaaatggcaa agcactttct ccaatgcctt tcatcaatgc agattttgtt gaagtggcat
    60301 atagattata atagccttcc ccattttcga ttctggcttt ttctaatctg taacctcctt
    60361 caacgatata tccacgttgg atacatgtag caatcacttt gctttggaca cctggtgccc
    60421 acgtccatgc tggattagat gcatcggcaa tatcacttgc tctggcagat ttgattggct
    60481 gattcgctga gtttgaagag gaaggggtcg aggatgccgc ttcttgctgt gctgcttgtg
    60541 cgaccgcagc ttgttgagcg gcttgagctg cagctgctgc ttgagcggct tgttttgctt
    60601 gttcttcagc tgcttttttc gcttcttctg cttttttctt ttcctcttct tcttttttct
    60661 ctttatcagt gagcatctta tctacttgtt tcaattgttc attcaactga gcagatagat
    60721 ctgtattttt cactttttct actgcttctt ttgccgtctt gtattggtcg cgtgttgctg
    60781 aatccactac ttttccgtct ttaaagacta tagctgtttt ttctttagct gtttgcaatt
    60841 cagcatattg atttttagct tctgtttgtg cttgttgaat caattttcca aaatctgtgt
    60901 tatccgtttc gattgcttgg atctctttat ctgctttcaa cttgatgtca tctgctagat
    60961 gatcatcgac gatggcaggt gctatgaacc actcattcac tttttggata tctcggatct
    61021 tagattggat atcttggtaa gttgtttcta actctgaata tcctttttca ttcttaagac
    61081 tggataaatc attttttagt tttgataaat cttgatgaat catatctgca cgaataaatt
    61141 gatggtgatc atctgtataa aaggcagcaa gtttctcatg aagttcttcc atttgttgct
    61201 gtctttttgc ttctgctgct acttcggctt ctactttttg atgatggtca taataagccc
    61261 agcttcctcc accgagtaga agtactgctg ctaaaacgag ataaggtact ttttttgatt
    61321 ttttcttttg cgctttatct ggatctgttt tttctaagtt tgattcttga tgtgtttttt
    61381 cagtatctgg cacgattgtt attgatttcg cttctgcttc aaacagctta ggctggttct
    61441 cttctttttc tatttttgct tcaagatcag taccctcttt gcttacagat tgattttcag
    61501 catcggattc actatttatt tcatcgggct ctgttgactt tttgtctgtg ttttcgagta
    61561 tttctttttt ctctgcttcc ggcagtttat tcgttttttc cttttctaat tgtttttcag
    61621 taaatacttc agttttttct gtgatatccg tttttacgtc ttttattttt actgtttctt
    61681 tacctgtggc gttttctcta tcagagtctt tttcagtttc ttgttccttt tctggctcta
    61741 ctttgttttc ctgtgcaatt ttttcactga tcattttgag cagctctttc gcgtgctctt
    61801 cttttgtatc ttcacgatgt gctttgatat aagcggatag tatcgaattt tcttcctcat
    61861 tatcgacgat ttctttcagt tcagctactc ttcttttttg ttttgattca agcgtttctt
    61921 cttgattctt tcctgattct tccgaagtct catgaacagt tgctttcttc tgttcatttt
    61981 tctctatatt agttacttga tcgtgagcag gtggttcttc gtcttctggt tctgcttttt
    62041 cgaataattc cattacagat tctagaggta aatctttcaa ttccgaccat tcgattggat
    62101 cgtttaattc tgtatcagga aagactgcat cttcagttga tttatcctgc atagctgcat
    62161 ctgtatttgt ttcttcaatt gattctttta tttgctgatc ttctgcagtt atttgatgac
    62221 cgcagtctgg acagatagta ttctgctcca tttttttcga tccgcaattt ggacattttt
    62281 tcatcactta gcgatcggct cctttactag gtttacgcta ccatttaatc tatcatattc
    62341 tatacgtcac gccaatagct tatttttagg atttacttaa aaataatgaa tgaatttcct
    62401 tcctatagaa aaaaaagctt gagactgcgt agtctcaagc tttttttctt ttaaaataaa
    62461 ccaaacagtt ttactgattt ctcttctggt caatagtcca cgcttattct aagaaatctt
    62521 ttaattgttt tgaacgagaa ggatggcgca attttcttaa tgctttagcc tcgatctgac
    62581 gaatacgttc ccgagtaaca ccaaatactt tccctacttc ttccaatgtt ctcgtccggc
    62641 catcatctaa accaaaacgt aagcgaagga cattctcttc ccgatcagtc aatgtatcta
    62701 gtacatcttc caattgttct tttagtaact cataagctgc gtgttctgct ggacttgttg
    62761 cttcctggtc ttctatgaaa tcacctaagt gagagtcatc ttcttcaccg attggcgttt
    62821 caagggaaac aggttcttgc gcgattttca agatttctcg gactttttct gttggaagat
    62881 ccatttccgc accgatttct tctggcgtag gttctcttcc aaggtcttgc agcaattgac
    62941 gttggatacg tatcaattta ttaattgttt caaccatatg aactggaata cggatcgtac
    63001 gtgcttggtc agcgattgct cgagtgatgg cttgacgaat ccaccatgta gcataggttg
    63061 aaaacttaaa tcctttgcgg tagtcaaatt tttcaactgc cttcatcagt cccatgtttc
    63121 cttcttggat caagtcaagg aactgcatgc ctcgtcctac ataacgttta gcgatactta
    63181 ctactaaacg aaggtttgct tctgccagac gctgtttcgc ttcttggtcg ccttcttcga
    63241 ttttcaatgc taacgctact tcttcttccg cagttaaaag ggagacacgg ccaatttctt
    63301 tcagatacat acgaaccggg tcattgattt ttacaccggt tggcgcagaa agatcttctg
    63361 tttttgcttg ttcagctttt ttctcagcac tcttcaagct gtgaattgat ggatcaccat
    63421 tttcatccac cacactgata cctgcgtctt caatcttttg gatcaatttg tccatttcat
    63481 ctgcattcaa agtgaatggt gtagcaagct gattggataa atcatcatat acaacttgtc
    63541 gtttgggttt gttttctttg atgaaagctg ctactgctgc ttcatacgtt tttttatctg
    63601 ttccatttgc cataaaagaa ggcccccctt gagtagctat ttggcttgtt ttaactgttt
    63661 cgttaaattg atgatttcaa tcgtcaattc aagctcaagc tgtttgtttc cagttcgtct
    63721 ggcttcttgc tgcatttgtt tttttaatgt tatttcatca gctaagccag atttgctgat
    63781 cacatctagc aagtcttgga tttctcgtgg cgaactttct tctgccaccg gtaaatattc
    63841 gatttccacc accaaccgcc ttaaattttc atcttgcaaa aagtctaaaa actctgcaag
    63901 gttgaattca taatgttgtg agacatatgc atcgaataaa aaataaactt ctgcatatgc
    63961 atcatgaata aactgaaatt ctcgttcttt taaaatatta cggacagaaa cttctttaaa
    64021 tgcacgatat aatagaatct gctctgcctt ttctacttgc gtcaaaggtc tctttttccg
    64081 tgcagtttct tgtctcgtaa cctgagtgtg ttgactttcc tgaggttctt gacgattttg
    64141 ctgatttgtc cttcgaagat cgcgcagttg tttttgtatc gtctctctgc cgatctgaaa
    64201 ctctgttgac agttgagata gatacatatc ttgttcgatt ggtgaaacaa ctcggctaag
    64261 ttcaactagt aattcttcga ggtattcgat cttgtctttt tcattatcta aatttttccc
    64321 ttgttttaaa taacgtgatt taaaagtaaa gactgtttcg cgcccatgag ccactaattc
    64381 ttggaaagat gcttctccat acttacggag atattcatca ggatcaagct tttctggaac
    64441 gactacgaca gaaagtgcta atcgactgtt ttgccgaagc aattcaatcc ctcgattggt
    64501 tgcttcaaaa cctgcgttgt ctccgtcata gcaaaagacc aattctttcg tcagcttttc
    64561 catttgttgg atctgttgag ctgttagact tgtccccata gaagctaatc cagttttgat
    64621 accagcctgc catgcagcaa tcacatccat aaacccttcg aacaacaaaa tttctccgtt
    64681 tttccggata tcgcttcttg ctttatcaag attaaataaa acttgtcttt tattgaacag
    64741 ttctgtttct ggactattca agtatttggg ctgatctttt tcctgccctt tttcaggtgc
    64801 aagccagcgt cctgaaaaac cgatcgtctg gccttgagaa ttacgaagtg gaaacatcac
    64861 tctttgataa aaacgatcag acatacggcc atcatcatgc gtgacaaaca atccagagcg
    64921 ttctaacaat tcatttgaaa ttgattcatt cttgaatact tgctgaagaa aagaacgctc
    64981 attaggtgca aaacctatgt tgaattcttc aattaattct aaagacaacc cacgactttg
    65041 caaatattct aaagctggct gtccagcttt tgtatgcaat agcatgtgat gatagatttc
    65101 cgctgctttt tcatgagcag caatcagttt ccccgtagca gattcaggat tttggacagc
    65161 tatagtacgc tgacgccatt gatcttctaa cggtatctgt tcgaagtctg ccacttttac
    65221 cactgcttct ggaaaactta gaccttctag ttcttgaaga aaagtaaaca cgtttccgcc
    65281 tttaccacaa ccaaagcaat gaaaaatctg cttgtcttct gcaacagaaa aagacggtgt
    65341 acgttcttca tgaaaaggac acagccccaa gtaattttta ccagactttt tcaactggac
    65401 atattgtcca atcacctcaa cgatattcgt ttgactgcgt actgtttcga taacctcttg
    65461 aggaatccgt tgagccattt tttcaccccc tgctctattg atatcttttg ggtttaacag
    65521 aagatatttc aggagaataa ccggtaaaaa atcgcactaa ctgaaatcag tgcgatttta
    65581 aaggacacaa ttatacatgt ttgattgtat catatttcat tgctttttca agtataacac
    65641 atttctatct cattaagcat caatttgcta ctcttttcag taactgattt tgaatatcag
    65701 ccttccagta caatactcga agaacaatat ttacgagcat gaatacaaag aagtatccta
    65761 cgctctctcc caaccctaag tttacttcca aaattccatg gaacagcatt gcagctacat
    65821 atatccctac gatcgtcgtt actgctagga agatgcgcaa tgggttgaag ggataacaag
    65881 cttttacaac tgccatgcaa ctgatcccaa tcagcaagta atacatcaaa gtagtagttt
    65941 cagcatttcc ccatgcgaat gtttttccaa gtagatacac cgcaatgata ttcactacta
    66001 caagcaaggc atttggtaaa gcattaataa gtgctgtagg caaataacgg taagtgattt
    66061 ttcttttatc ttgttcaaaa gataaaaaga aggaaggata cccttcaatc gctaaatcaa
    66121 tcagcgtgat ttggataggg ataaacggaa atccaattgc tgtaacggca catataatcg
    66181 ataaaataaa tgaataaatc gttttgataa aaaagatgcc tgagactttc gtcacattgt
    66241 tgaccactcg gcgtccttca aacaggactt ctggcaatgt agtaaaatca gagtccaaca
    66301 ataccagatt cgcaatctga cgtgttgctc catcaccttc tgccatagca atgctgcaat
    66361 ctgcttctct taacgccaaa acatcattca caccgtcgcc tgtcattgca accgttctgc
    66421 cgctttcttt caattcattt accagcaatt tcttttgctg cggactcact cgtccaaaaa
    66481 ccgtatagcg atgagcagct tctcgcactt ccatttcttc agtaatttga gaaagatcga
    66541 catacgcatc ataattcggt aatcctgcac gtctagcgat attggagaca gtaaaaggat
    66601 tgtctccaga aatcactttc agatccacac cttcctcatg aagataagct agtgtttctt
    66661 gagcgttttt tcggattgga tcatcgattt caaacagagc aaccggctca acaaatgctg
    66721 gtttttcttc gttcaattgc tgatttggag cgatccccaa cataagtacg cgatagccat
    66781 tcgcttgggc tgtttttaga ctgtccggaa gccgatcttc ttccaccaaa cgttcaggcg
    66841 ctcctacgta cacgactccc agttctggaa attccatcgc gccccatttg cgatcagaag
    66901 aaaatgcgac tttgtttgtc acatcatacc gattagaaag ctcaaaataa tctctcatag
    66961 cccgcatagt gatgttgtta tcactgcttt ctgccagata cgtccccata atttctggga
    67021 tggctttctc gtacagcgga tgtagtgctt ctacccgctg gatactcatt ttcccttcag
    67081 taatggtccc tgttttatcc aagcataatg tatcgacatg ggccagcgtt tcaattgaat
    67141 acatgtcttg aacaaggatt cgtttttttg ccagtttggt tacccctgtc gttaatgcaa
    67201 tacttattag caataccaaa ccctttggaa gcatgcctaa caaagctgct gcagatgcaa
    67261 taacagaaat tttgatagaa gcatcgcgga tgaacagtgc ttccaaaaat agtatgatcc
    67321 ccaaaggaat aatcacgaaa ctagtgaatt tggatacttt gcgaatcgaa tctacaagtt
    67381 cagaacgaat agctttgtga gtctttgcct cgctagtcaa gcggacagca taattatctg
    67441 cacctactcg gataacttca gccatgacag aaccgcttgt caaaaagctt ccagaaagca
    67501 attcagctcc agtttctttg acaatcaaat cagattcgcc tgtcaaaaga gcttcatttg
    67561 cttctgcccg tccagatata acctgtaaat cggctggtat ctgttctcct gctccgattt
    67621 ttaccaaatc tcctaatacc agctctttag tagaaatcga ttgttcttta ccgtcccgga
    67681 tcactagtac ttctgattgg gaaacaatcg ataatttccg tacaagattt cttgcatgta
    67741 tttcttgata aattccaata acgatattga cgacaataat tgctaaatac gccatgttgg
    67801 aatacgcacc tacaaataac agacaaatcc caataccaaa gttcagaaaa ttgaataacg
    67861 tcaatatatt atcgctgaat atttgttttg tactttttga tgcatcttcc tggtagtcat
    67921 tttgctggcc agaagccatt ttctgaacta cctcttgctg tgtaagtcca ttcattttct
    67981 ttttctccat tttccgccaa ctttcaaaaa taatcacgtg tttaagtcta gcgtgttcca
    68041 agattaaaaa caacttgttt ttataaaatt tatagaaaaa cacacgaatg attttacaaa
    68101 aaagatgcca acctttttgt ttgaatcacc cgtgtgctgt ttttattatc aatctatctt
    68161 tacttatatt gttcctccaa acggctcatc caccaaccta gtgctgtacc ggctataaaa
    68221 agaacaggac aagctagtac cccagcaact cccaatcccg cgtaatcggt aggaatgatc
    68281 ataatcgttg aagcaaaaac tacacctaaa atgaaatgga atagcttgct atatgccttt
    68341 gagaaaatgt aatccatgat ttttgacaat ccaagaacac aaagaatccc accaattccg
    68401 atcggcacaa tcacttcaag tcgtacttct ttaaatccgt cagccatcgc tttatacaat
    68461 cccatataca ccaaaaaatt agaagggctc aatcctggga cgatcatacc caaaccaatc
    68521 aatccgccgg caatcagcca tgttccaaaa ttctgatcga cttgcccgtc aaataattga
    68581 gcgccgtata ataaaaacaa ataagccaga acaaaagtaa caaccatgat gatcacatca
    68641 gaagtatctc ttcctttttt ccctgcttct ttccataacg caggaacagt tccagcgata
    68701 catccgacaa aaaaccataa tatcgttgtt tcatacgcac ctaataaaaa actgactaaa
    68761 aaagaaagta gaaagatgcc tgtcactccg cctagaccaa caggcagaaa aaacaaaaca
    68821 ttttctttga aattttttgt aaggtgggct aaaaaagaaa tcagccgctc atacatgcca
    68881 aagacagctg ctaatgcacc accgctgact cctggcaaga taaatcctga accgataaac
    68941 attcccttca caaaccgtaa catccagtct ttggttgtgt accccacttc ttgattttcc
    69001 attttttgcc ttttttccac tatttgcgta ctccttcttt catttaattt tattcatgat
    69061 tgaacatttc ctgctatttt acttaaagac tttttcatag gtctctatta ttttttcatt
    69121 cattttgaca atatcaggat aaaacatgtt acctccatta tgatagagat agccgccatt
    69181 gtaaagcaag gactggatcc gccaatatcg gtattgtttc ccttcctcat ttcctaaaag
    69241 tgggctcagc acatctttag aatacgcttc tgctaattct actgtgtttt ctccgccatg
    69301 attttttaca taggcaatat aatctttccc aaaattatat gcttggacag ctgtccataa
    69361 atcgcatcct tgtttctttg cttctactat catttccgcc aaatatttga caccttgatc
    69421 aatactgtca gctggattat caatgatctc agcttctcca tgcagacttt ccgagctctg
    69481 catgagatct gtcccttttc cttttgattc ggtcaatatt atcgccttga tcaaattctc
    69541 gtagttttcc atatgataat tttttgcagc tgttgttatt tctatttgat agctttccac
    69601 tcgttttacc gaacgataag ttcttcctca taaaaacaac accgcaccaa taaccgtcag
    69661 aatgatcatg taaaaaagaa tacggataat agataatcgt tttcgcttca tttcatcacc
    69721 tagttatttt gacatctttt tttatcttac tatttcttta tcttcttggc tatttcttcc
    69781 ttgatttctg tgtacgcctt aagaaaaaat gaattttcct gtattttttg acatcttacg
    69841 aaaatgatcg ttgtttttca gtaaaaacaa ttgcccaatg actgatataa tcgttatact
    69901 ttacacagta ggtgattatg tgaaaaaaga aaagaaatat gcaaaaatgc cagatgggag
    69961 cgaaatttac tatgaaaaga gcggtcaagg cttccctctc tttttactgc atggcaatga
    70021 cggcagcggc cgcttttttt cagaacaggt ccctgtactc gaacgctact ataccgtgta
    70081 tctagtagat agccgaggac atggtcgttc gacaaacgaa gcatctatgt tgaattttca
    70141 gttaatggcc gaggatctga atacgatcat gttgctggaa aaaatcgatc aggcagattt
    70201 tcttggattt agtgatggag caaatctagc actggtattt gccagcagct tccctaaaaa
    70261 agttcatcga ttgattttaa attctggaaa cacgcttgtt aaaggcgttc gtttttctgc
    70321 cagagtcatc agtaatattc attatgcatg ggtatggtta ctctctttat ttcgcccaag
    70381 tcttcgcaaa aatcttttag ttatcaaact tttgctgcat gacatcgggc ttacagaaaa
    70441 tgatttaaaa aaaatcaact cccccacttt gatcatcgtg ggaaaaaaag atgtaatcaa
    70501 gctaaaacat tctttgtata tagctaaaac tataccaaaa gcttcctttg tgcttgtgaa
    70561 agaacaagga catgaattag ctagaaaaga tcctgaacgc ttcaatcgag aagttcttca
    70621 atttctttct gaaacataac tattaggaat agaaggtgat ttatttgtta aaaaatacca
    70681 tacaatggct gaaaaaccac ctaggactgt tcaaaacaat ctttttgatt tctgtcattg
    70741 tcattattgt cggtgaattg atgtccatcg gtaaaactct atctatccag caattaggag
    70801 aaacgtttgc cactatacct gtatggaaaa gcggactaat gctattgatt ggtcttatct
    70861 ctgtgttacc tatggttggt tatgatatta ttttgaatcg gatgcttgaa caaaagcaga
    70921 atcctcgtta cctgtttgag acaagctggc tgatcaatac gatcaacaat attgccggtt
    70981 tcggcgggtt tgttagtgtg gggcttcgct ctgaactata tggacaaaag aaagagagca
    71041 gaaacgtgat ccaagcatta tcgaaagttt tcttgttttt gatggctgga ctttctattt
    71101 acagtctgct ttctttttta cttgtagtct tcacgccagt tgctcctttt ttgaagcaat
    71161 attggatatg gttgatcggc ggcggtctat attttcctgt cgtcttttta tttactactt
    71221 tcaaaaagaa aggattcctt ggtggtacct cacttaaaac tcaaggacag ctattgctag
    71281 tttcattgtt ggaatggacc ggtgtcctgt ttagtttcct ttctgttggt tatttaatgg
    71341 aaatccggat tgatctgtgg caaacaattc cattattcat tgctgcttca gtgataggaa
    71401 tcgtgtctat gattccagga gaaattggga gtttcgatgt aatgatgatt atcgggttgt
    71461 ccgctattgg tgtgccaaga gaaatagtcg ttgtgtggat cttgctctat cgcctgttct
    71521 actacatcat tccgtttttg attggaatcg tctttttctt caaaaatatc ggttccactt
    71581 ttgatcagcg ttattctggt atccctaaac aattagcaac agaaattgcg cataaaatcg
    71641 tggttgtctt attatacttt tctggaatca tgctagtact ttctgccact atcccgcaag
    71701 cttttacaga gtttcgctgg cttcatagtt tgaacccatt gaaatttcat tttattatcc
    71761 aatttcctag tatactattg ggatttcttt taatcattat gggcagaggg atcgcagcac
    71821 gtgtgaaacg agcatatttg cctacaatct tcttgattgt tctagcttta ctttatgttt
    71881 tattaagtga ttttagtttc acaccggtgg ttttcttgtc tattctgctt ctgatcattc
    71941 ttgcttctaa aaacgaatta tttcgggaac aattgatcta ttcatgggag tggcgtacga
    72001 tcgatggaat cattattggt gcactgtcct tgctttacat cgttattggg gtatacaatc
    72061 tgccggattt ccctcatcgg cgtcaccatt ttatttcctt tttcttattt ccttctgaaa
    72121 agatttggtt ttcgggattg ttggccatca tcgctgttag tttcatgatc gttctatttg
    72181 ttcatttcct tcaaggagaa aagaaacaga ttggcgaagc ctttaatgaa gaaaaggccc
    72241 tgaagatcct tacaacttat ggaggaaact ccgatagtca attgatcttc ttaaaagata
    72301 agcggatgtt tgcctatgaa aaagacggtg aaccaactgt tcttctccaa ttcgcttgct
    72361 tcaataataa atgtattgta atgggtgatc cttctggtaa gaaagaagat tttccagaag
    72421 caatcgaagc ttttatcgaa gaaacagatc gactatgcta tttaccagtt ttctacgaaa
    72481 caagcgaaga gattgttatg attttgcatg aattcggcta cgatttcatt aagatggggg
    72541 aagaagctta tgtagacctg aatagtttta caacttcagg gaaaaaaatg aagggcactc
    72601 gtgctgtctt gaatcggatc gaacgagaag gatttacatt tgatgtctta caaccaccat
    72661 tttctactga gcaaatgagt actttcaaaa atatctctga taattggttg ggttcacgaa
    72721 aggaaaaagg gttttcttta ggctttttct ctgaagatta tctacaaaga gcgcctattg
    72781 cagttgtcaa aaatacccaa gaagaaattg tcgcttttgc aacgatcatg cctacttaca
    72841 cgaacaataa agtaggaacg attgatctga tgcgatatga ttctaaaaaa gcaccttctg
    72901 gcagtatgga tttcttgttc ttgcatttgt ttgcctatat gaaagaagaa catatccaat
    72961 ggttcaattt agggatggcc cctctttcaa atgtcggaac ttccagaaag agttttttac
    73021 aggaaaggat tgcatacttg gtttacgagt ttggttctca tttttattct ttccatggat
    73081 taagagaata taaaagcaag tacgctacaa actgggtctc acgttatact ctatattcta
    73141 gagatagttg gattgcatat gttatgattg ctttgctgat tattgataat gcgccagttg
    73201 agcagacaca aggtagaata agtggtttga aaaaatggat acgaagaaag tattaaaaac
    73261 tgcataccga tagatgaaca ctctcatgat gaataaaaga gactgaagta aaacgaaagt
    73321 tcatgcttct acaatctctt cttatacaat tgaagaacaa agagcggtcc aaacagaaat
    73381 cctgtttgga ccgctctttt attttaaaca tttttcatta ccaaaatatt cgagtcgcgt
    73441 ttcttatgct tcgatctctg taacgatacc tgaacctact gtccgtccgc cttcacgaat
    73501 tgagaatgtc gttccgtttt caacagcgat tggatggatc aagtcaacat caatcgtcac
    73561 gttgtcacca ggcatgacca tttctgtatc ttctggcaat gtgattgttc ctgtaacatc
    73621 agttgtgcgg aagtagaact gtggacgata gttgttgaag aatggagtat gacgtccacc
    73681 ttcttctttt gtcaacacgt acacttctgc tttgaatttt gtatgtggag taatggaacc
    73741 tggtttagca agtacttgtc cacgttcgat atcgtcacgt tggatccccc gtaacaacac
    73801 gcctacgtta tccccagctt ccccgtaatc taacgtttta cggaacattt ctacacctgt
    73861 tacaactgct ttttgtgttt caggtttgat ccctacgatc tctacctcat caccgacacg
    73921 aacagcacca cgatcaatac gacctgaggc aacagttcct cgacctgtaa ttgagaagac
    73981 gtcttccact ggcaatagta atggtttatc tgtatcacgt tctggtgttg ggatatattc
    74041 atctactgta tccatcaatt ccataatagc agcttcagca tctggatcgc cttgcaatgc
    74101 ttttaatgcg gaacctttga tcacaggagt gtcatcgcct gggaaaccat attcgctcaa
    74161 taactcgcga acttccattt ctaccaaatc gatcaattct tcatcatcga ctaaatcaac
    74221 tttgttcaag aaaacaatca ggtattttac accaacttgg cgtgacaata aaatgtgttc
    74281 acgtgtttga ggcatcggac cgtcagttgc agaaacaact aagattgcac catccatttg
    74341 tgctgcccct gtaatcatgt ttttcacata gtccgcgtgt cctggtgcat caatatgcgc
    74401 gtagtggcgt ttttctgttt catattctac gtgtgcggta ttgatcgtaa tcccacgttc
    74461 acgttcttct ggagctgcat caatactagc atagtcttga ggatttgcta ggcctttttt
    74521 gcctaatact gtagtgatcg cagcagttaa agtagttttc ccatggtcaa cgtgtccaat
    74581 cgtaccaatg ttaacgtgtg gtttacttct gtcataatgt tcttttgcca taatttacaa
    74641 acctcctaaa taatatagat cactgaaaaa tttcagctct caccttttta ttatagtctt
    74701 tttttgacta aatcaaaaag aatacgtccg acttactttt tgtaagattc gaactaagct
    74761 tattatacgt caatattggt caaagtcaac taagagcact cgtctgtctt atacgcgaaa
    74821 aaagtacctt ttataaataa aaaaatgtgt tttttgagaa aaacttcaag atagtcctta
    74881 actttctttt gaagcaataa gaacaaaatg aggaaaagtt taaaattcag ctgttgccaa
    74941 caactttcaa tagacgaaat cttctatttc gttaataata aggaaagagg tgaagtacat
    75001 gaaaaaatta attggcgtac ttgtcgtttt aggcatattt ctcggcggaa gttttgcagc
    75061 ttatcattat ttttacggcg gcgaagctta ttatacaaaa atcacgacga atggcgaaat
    75121 gtcagctacc caagcagata acggagagaa attcacgact tatacctaca agcaagcggc
    75181 ttataataaa gatggtgaaa aaaaacaggt gacgcttcgc gaagaaagag aacatccatt
    75241 aaagatgaat gcgtatctta aactcaaagt caatcctcgt aaaggtgtat taagctggga
    75301 agaaataaag gcttctgaag tgcctaaaaa tgcggcagaa aaaatcgata attagtaaat
    75361 ggtcttaaaa ttttattaga taaaaagagg ctgggacaga agcgtttaac tccaagaaat
    75421 aagaaggagt tgcttctgct tccgccgttt atacgtgttt agagcgtgag acaaaagtgt
    75481 tctttacttt tgtctcacgc tctttttttg ttatattcgt cttttccgat ccttctcttg
    75541 acacaattca tttaactgat cactggtact tgaacaccta atattctagt catttttata
    75601 aacgattcaa tacttcatcc acatttttga tcatcacgga tatcgtacca tccggattat
    75661 tcacaaattc aatcaaatct gggttgcgat atacatctac tggtacgatc agttcgatcc
    75721 cgtttgatag cttgaatttt tgttttccaa attttttctc agaaatttct tgtacttctt
    75781 ttacaggagg tgcttctggg acaaatcctt gctcttgtac ttcttcttta aaagccattt
    75841 ttgccgtgat gttttccttg aagacttttt ccgcaatcat ctcatgatcc aaccgacctt
    75901 tttcttctat cgtatcatag acagcttctt tcaaatcagc catgatatca aattcttctg
    75961 tctcaaattt ttttccaaga tgcttggcta ctttttggat cacttttaca ttttcttcta
    76021 aagaaggtgc aggaacactt tcgatcactc ttccagaaaa ataaagctct tttttgccag
    76081 aaaactcata ttttttttca attaattcgt aggtccaatc agtcaaattc acagcgaatg
    76141 cttcatctgc tttttgtgtt ttcgccccta gaattgctcg attcaaaatc aagcggttgt
    76201 cgatccctgc ttcgtctgct tcaacaaagt gagtgtaagc ctcacgataa ttgactttca
    76261 ataaagataa gtacatcact gtatctaatt catacaagac aacaaataca tctgcactag
    76321 gtgcttcttc actttcttgg tagatatcga accaccgctg aacgattgct tcacttgctt
    76381 ccacaaaatt ttcttgagcg attttaagtg attcaacgat catgctttct tctgctagtt
    76441 gtccagtttt tgtttgagca gaagagattt tttggatctt cttttgaaga aaatcacgaa
    76501 tatattcttt tgtcagatcc agctcttttt gtgaaaagac tggagaacca gtttctctgt
    76561 caataatatg cagaattgct ttttttaaat agatatccat tttctcattc ccttctgtct
    76621 tagtttacgg aaaaaaaatc aaaaatacca gaatcaaaat cattttcttt taaacaaaaa
    76681 tttcaagagt agaaacaaaa tggattcttt ttttcgaaaa atgcgctaca cttatagttg
    76741 aacgaataaa aaaggagctg aaagtatgaa ttcattaaca agcacttatc gtctatcaaa
    76801 tggttacgaa atcccggtag taggattcgg cacatggcaa acacctgatg gggatgtcgc
    76861 tgtttcctct gttaaagaag cgctggctgc aggttatcgc catatcgata ctgcccaagg
    76921 atacaagaat gaagaaagcg tcggccaagc gattaaggaa agtggaattc ctagagaaga
    76981 gatattcttg acaacaaaat tatggaatgc aaaccacagc tatgaacttg tgatgtcttc
    77041 ttttgaagaa tcattgaaga agctccaaac agattattta gatctgtttt tgatccactg
    77101 gccaaaccct gttgcttttc gtgataattg ggaacaagca aatgcagata catggcgagc
    77161 atttgaagaa ctgtatgaag caggtaaaat caaagcaatc ggtgtgagca atttcttacc
    77221 ccaccatcta gatacactag caaaaacagc aaaaattatg ccgatggtca atcaagtttt
    77281 ccttgcacca ggcgaattac agacaactgt agttgagtat gcaaaaaaac atgatatgat
    77341 cctcgaagca tatagtccat taggcactgg taaaatcttc gatgtgcctg aaatgaaaca
    77401 aatcgctgaa gcacatgaca agacgattgc acaagttgct ttgcgttggt cgctgcaaca
    77461 cgaattcctt cctcttccta agtcagtgac accaagcaga atcaaagaaa atactgaatt
    77521 atttgatttt gaattaacag aagaagaaat gaaacaaatc gatcagttag atggtgtagt
    77581 cggcaaagca aaagacccag atactaccca attttaagtc gaaaggtgat tttatggatc
    77641 caatcgaacg cttgaattct ctctcggaag aagttaccca gacttttcat tccgattttg
    77701 tctttttgat cgatgcagag aaaatccaac attttcctgc aagaaactgg acacatgatc
    77761 aaatcatcga agaactgaaa aaacggttcg atcattcgct aatggtcaaa ccctggcacg
    77821 aacatgaagt catttattca cctgaactac ctgtttttgc cttgataccg aaaaaataga
    77881 aagaatggaa cggattatgt atatatacat aatccgttcc attttttatt tttctttcaa
    77941 aaaacgggaa aatacgcaaa tttttctgtt gtaatttgcg tatacgcaag tttttttgca
    78001 ttactccttt tcatttggct gtttttttct tataatcgaa agggtatgag cgaaggagag
    78061 aacatatgaa gaaaaaacag aaacaaaaat tattaaatca attccgtcct tcattggatg
    78121 gtgtaagagg acaattattc cgttctctag aagaagagag cttgcgacgt tatggtttgc
    78181 cgttacaagt catgcttgat cccaaaaacc gtcaaatctt aacgatcgga ttagctggga
    78241 aaacaaatga agatacacgg atcaacgtgc caatcgatga caacttcaat actgtattaa
    78301 agagaattcg ttcaggagaa aacgggattt tcgaacgatt ccgtgacaat cttcttattg
    78361 aaatcgtgtc ttactggaat gatcaacgat tgaaaaacga tgaaccaact gcgcaagctg
    78421 ttgcgacacc agttacagaa gaaacagtca gtgtgccaga agaaaaaacg gaaaaaccaa
    78481 aagcggacac aactgaaaat acacgctcaa ctgatacgaa tgccgcttta agttttgctg
    78541 atttttcaaa agccgttgct gagtatccta aattttacac agaacaaaat gaacatgaag
    78601 tagttattaa tgaaaaaaat gctgatgaac ctcgtaaatt agcaactatt tctatgacta
    78661 ctgaaaatga gttcgttatc gaaaaagcac tcgaacggaa atacaaagtc aaattgactt
    78721 tgattccttt gatcgaacaa tttgcagcga cagcgattac tgatcgataa aaattctatt
    78781 tgtcataaaa ggctgggatt taaaatccca gcctttttag tcatataata atttctacag
    78841 caagtaaaaa gaaattcctt ctaacatcag gctcaaatat cagcttgacc tgtccaacaa
    78901 atcacctatg atcctacaat gttaggcgac ttctcttcta cctgaagata tcttggagtt
    78961 gcctgatttc ttaagatgcc taaccttaac tataaaaaat tctaataata aacatatttt
    79021 ctgatagaga aaaaagcggt tctataatat tttgtgttgg tggaaaatcg aaagcgattt
    79081 tctactaaca cttttttctt cgtttcaact caaaaagaga ctcacttttg gtaaaattta
    79141 gtcgaccaaa acgtcaccct accaaaggag tctctcaatg gataatcata ctagaaaatt
    79201 actcggatta acagataaac atttattttt tgatgaagaa tggctgattg aaaaagaata
    79261 taaaggcgtt caagcgcagt ttattaaagg gagattggat gactcacctt cccattgtga
    79321 acactgtgga tcgattcgta ttatccgcaa cggttcctat acgacacgca ctcagatgtt
    79381 gaaagtcaaa gaaaagttga ctattttaga attaaaacgt acccgttttc tctgccatga
    79441 ttgtggacgg accttttctg cgaaaacgga cttagttgat gaacatcatc aactaacaaa
    79501 ggaactgaag caggcgattc tcatggaact gtacgaaaat caatcacgta aactaatcgc
    79561 taagaagtac ttcgtctcgg atgggacggt gacacggatc ttgcgtgaag caacgaagca
    79621 ttaccagcca cgtatgaact tccttccgac ggtgttgtgt atggatgagt tcaaatcaat
    79681 gaa
//
LOCUS       DADVXE010000005        78791 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.005, whole genome shotgun sequence.
ACCESSION   DADVXE010000005 DADVXE010000000
VERSION     DADVXE010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 78791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.005"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..434)
                     /locus_tag="KB913_000320"
     CDS             complement(<1..434)
                     /locus_tag="KB913_000320"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBB6818712.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQ"
     gene            680..1627
                     /locus_tag="KB913_000321"
     CDS             680..1627
                     /locus_tag="KB913_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6818713.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(1838..3910)
                     /locus_tag="KB913_000322"
     CDS             complement(1838..3910)
                     /locus_tag="KB913_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6818714.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(3843..4220)
                     /locus_tag="KB913_000323"
     CDS             complement(3843..4220)
                     /locus_tag="KB913_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBB6818715.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(4349..4927)
                     /locus_tag="KB913_000324"
     CDS             complement(4349..4927)
                     /locus_tag="KB913_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6818716.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            5059..6351
                     /locus_tag="KB913_000325"
     CDS             5059..6351
                     /locus_tag="KB913_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6818717.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(6411..7529)
                     /locus_tag="KB913_000326"
     CDS             complement(6411..7529)
                     /locus_tag="KB913_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBB6818718.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(7543..8964)
                     /gene="arcD"
                     /locus_tag="KB913_000327"
     CDS             complement(7543..8964)
                     /gene="arcD"
                     /locus_tag="KB913_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBB6818719.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(9210..10331)
                     /gene="mnmA"
                     /locus_tag="KB913_000328"
     CDS             complement(9210..10331)
                     /gene="mnmA"
                     /locus_tag="KB913_000328"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBB6818720.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            10735..11334
                     /locus_tag="KB913_000329"
     CDS             10735..11334
                     /locus_tag="KB913_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HBB6818721.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(11472..12758)
                     /gene="efmA"
                     /locus_tag="KB913_000330"
     CDS             complement(11472..12758)
                     /gene="efmA"
                     /locus_tag="KB913_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBB6818722.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(13029..13373)
                     /locus_tag="KB913_000331"
     CDS             complement(13029..13373)
                     /locus_tag="KB913_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBB6818723.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(13510..14655)
                     /locus_tag="KB913_000332"
     CDS             complement(13510..14655)
                     /locus_tag="KB913_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6818724.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(14835..15809)
                     /locus_tag="KB913_000333"
     CDS             complement(14835..15809)
                     /locus_tag="KB913_000333"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBB6818725.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(15889..16764)
                     /locus_tag="KB913_000334"
     CDS             complement(15889..16764)
                     /locus_tag="KB913_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBB6818726.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            16894..18801
                     /locus_tag="KB913_000335"
     CDS             16894..18801
                     /locus_tag="KB913_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBB6818727.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(19342..22620)
                     /locus_tag="KB913_000336"
     CDS             complement(19342..22620)
                     /locus_tag="KB913_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBB6818728.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(22891..23436)
                     /locus_tag="KB913_000337"
     CDS             complement(22891..23436)
                     /locus_tag="KB913_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6818729.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(23448..24140)
                     /locus_tag="KB913_000338"
     CDS             complement(23448..24140)
                     /locus_tag="KB913_000338"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBB6818730.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(24159..24443)
                     /locus_tag="KB913_000339"
     CDS             complement(24159..24443)
                     /locus_tag="KB913_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818731.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(24456..25019)
                     /locus_tag="KB913_000340"
     CDS             complement(24456..25019)
                     /locus_tag="KB913_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6818732.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            25247..25909
                     /locus_tag="KB913_000341"
     CDS             25247..25909
                     /locus_tag="KB913_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBB6818733.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            26033..27229
                     /locus_tag="KB913_000342"
     CDS             26033..27229
                     /locus_tag="KB913_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBB6818734.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(27330..28706)
                     /locus_tag="KB913_000343"
     CDS             complement(27330..28706)
                     /locus_tag="KB913_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6818735.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(28743..29610)
                     /locus_tag="KB913_000344"
                     /pseudo
     CDS             complement(28743..29610)
                     /locus_tag="KB913_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
     gene            complement(29699..30724)
                     /locus_tag="KB913_000345"
     CDS             complement(29699..30724)
                     /locus_tag="KB913_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6818736.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(30742..31416)
                     /locus_tag="KB913_000346"
     CDS             complement(30742..31416)
                     /locus_tag="KB913_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6818737.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(31600..32493)
                     /locus_tag="KB913_000347"
     CDS             complement(31600..32493)
                     /locus_tag="KB913_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6818738.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(32567..34264)
                     /locus_tag="KB913_000348"
     CDS             complement(32567..34264)
                     /locus_tag="KB913_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6818739.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(34257..35570)
                     /locus_tag="KB913_000349"
     CDS             complement(34257..35570)
                     /locus_tag="KB913_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBB6818740.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(35570..39607)
                     /locus_tag="KB913_000350"
     CDS             complement(35570..39607)
                     /locus_tag="KB913_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBB6818741.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(39620..40078)
                     /locus_tag="KB913_000351"
     CDS             complement(39620..40078)
                     /locus_tag="KB913_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6818742.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(40376..40894)
                     /locus_tag="KB913_000352"
     CDS             complement(40376..40894)
                     /locus_tag="KB913_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBB6818743.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(40896..41513)
                     /locus_tag="KB913_000353"
     CDS             complement(40896..41513)
                     /locus_tag="KB913_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBB6818744.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(41510..42364)
                     /locus_tag="KB913_000354"
     CDS             complement(41510..42364)
                     /locus_tag="KB913_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6818745.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(42361..43272)
                     /locus_tag="KB913_000355"
     CDS             complement(42361..43272)
                     /locus_tag="KB913_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6818746.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(43313..44647)
                     /locus_tag="KB913_000356"
     CDS             complement(43313..44647)
                     /locus_tag="KB913_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6818747.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            44855..45685
                     /locus_tag="KB913_000357"
     CDS             44855..45685
                     /locus_tag="KB913_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBB6818748.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(45929..46247)
                     /locus_tag="KB913_000358"
                     /pseudo
     CDS             complement(45929..46247)
                     /locus_tag="KB913_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(46369..46563)
                     /locus_tag="KB913_000359"
     CDS             complement(46369..46563)
                     /locus_tag="KB913_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818749.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(47068..47253)
                     /locus_tag="KB913_000360"
     CDS             complement(47068..47253)
                     /locus_tag="KB913_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818750.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(48103..48444)
                     /locus_tag="KB913_000361"
     CDS             complement(48103..48444)
                     /locus_tag="KB913_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6818751.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(48444..48674)
                     /locus_tag="KB913_000362"
     CDS             complement(48444..48674)
                     /locus_tag="KB913_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6818752.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            48961..49299
                     /locus_tag="KB913_000363"
     CDS             48961..49299
                     /locus_tag="KB913_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818753.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(49504..49743)
                     /locus_tag="KB913_000364"
     CDS             complement(49504..49743)
                     /locus_tag="KB913_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBB6818754.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(49719..50066)
                     /locus_tag="KB913_000365"
     CDS             complement(49719..50066)
                     /locus_tag="KB913_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBB6818755.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(50798..51379)
                     /locus_tag="KB913_000366"
     CDS             complement(50798..51379)
                     /locus_tag="KB913_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6818756.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(51562..52188)
                     /locus_tag="KB913_000367"
     CDS             complement(51562..52188)
                     /locus_tag="KB913_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6818757.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(52210..53541)
                     /locus_tag="KB913_000368"
     CDS             complement(52210..53541)
                     /locus_tag="KB913_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBB6818758.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(53696..54097)
                     /locus_tag="KB913_000369"
     CDS             complement(53696..54097)
                     /locus_tag="KB913_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBB6818759.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(54183..54389)
                     /locus_tag="KB913_000370"
     CDS             complement(54183..54389)
                     /locus_tag="KB913_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818760.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(54484..55986)
                     /locus_tag="KB913_000371"
     CDS             complement(54484..55986)
                     /locus_tag="KB913_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBB6818761.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(56004..56459)
                     /gene="argR"
                     /locus_tag="KB913_000372"
     CDS             complement(56004..56459)
                     /gene="argR"
                     /locus_tag="KB913_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBB6818762.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(56557..57174)
                     /locus_tag="KB913_000373"
     CDS             complement(56557..57174)
                     /locus_tag="KB913_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBB6818763.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            57395..58768
                     /locus_tag="KB913_000374"
     CDS             57395..58768
                     /locus_tag="KB913_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6818764.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            58843..59955
                     /locus_tag="KB913_000375"
     CDS             58843..59955
                     /locus_tag="KB913_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBB6818765.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(60027..61664)
                     /locus_tag="KB913_000376"
     CDS             complement(60027..61664)
                     /locus_tag="KB913_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBB6818766.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(61832..62440)
                     /locus_tag="KB913_000377"
     CDS             complement(61832..62440)
                     /locus_tag="KB913_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6818767.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(62824..63975)
                     /gene="queG"
                     /locus_tag="KB913_000378"
     CDS             complement(62824..63975)
                     /gene="queG"
                     /locus_tag="KB913_000378"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBB6818768.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(63994..64746)
                     /locus_tag="KB913_000379"
     CDS             complement(63994..64746)
                     /locus_tag="KB913_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818769.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(64887..65837)
                     /locus_tag="KB913_000380"
     CDS             complement(64887..65837)
                     /locus_tag="KB913_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBB6818770.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(65838..66677)
                     /locus_tag="KB913_000381"
     CDS             complement(65838..66677)
                     /locus_tag="KB913_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6818771.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(66674..67420)
                     /locus_tag="KB913_000382"
     CDS             complement(66674..67420)
                     /locus_tag="KB913_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6818772.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            67658..69028
                     /locus_tag="KB913_000383"
     CDS             67658..69028
                     /locus_tag="KB913_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6818773.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(69083..69979)
                     /locus_tag="KB913_000384"
     CDS             complement(69083..69979)
                     /locus_tag="KB913_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6818774.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(70093..70263)
                     /locus_tag="KB913_000385"
     CDS             complement(70093..70263)
                     /locus_tag="KB913_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818775.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(70260..70937)
                     /locus_tag="KB913_000386"
     CDS             complement(70260..70937)
                     /locus_tag="KB913_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBB6818776.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(71028..71933)
                     /locus_tag="KB913_000387"
     CDS             complement(71028..71933)
                     /locus_tag="KB913_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6818777.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            72108..73532
                     /locus_tag="KB913_000388"
     CDS             72108..73532
                     /locus_tag="KB913_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6818778.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            73578..74609
                     /locus_tag="KB913_000389"
     CDS             73578..74609
                     /locus_tag="KB913_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6818779.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            74616..75803
                     /locus_tag="KB913_000390"
     CDS             74616..75803
                     /locus_tag="KB913_000390"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBB6818780.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            75959..77341
                     /locus_tag="KB913_000391"
     CDS             75959..77341
                     /locus_tag="KB913_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBB6818781.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            77468..77698
                     /locus_tag="KB913_000392"
     CDS             77468..77698
                     /locus_tag="KB913_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818782.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(77898..78566)
                     /locus_tag="KB913_000393"
     CDS             complement(77898..78566)
                     /locus_tag="KB913_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBB6818783.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        22555 a        16519 c        14073 g        25644 t
ORIGIN      
        1 aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt cagttttcca
       61 ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt tcgatttgcc
      121 tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc tttatacgtt
      181 cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg aaaaggcgta
      241 cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa atattcttca
      301 aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc tgaaattggc
      361 tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa gccgataggt
      421 gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc ctttttctct
      481 atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa accgaggaaa
      541 catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac gtaaaatcaa
      601 attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat ataaacatac
      661 gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta atgaagaaaa
      721 aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg agttcgaata
      781 tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga agctagcctc
      841 agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag aagcggctct
      901 gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg ttgatctgca
      961 agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg atatcgattg
     1021 tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt tctttgcgaa
     1081 aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg gcgctcgtga
     1141 tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag aatacaaccg
     1201 attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt cttatgaaaa
     1261 ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca actactcgat
     1321 tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta tcggcgcttt
     1381 gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat tgttgtttgg
     1441 tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg gtggaatcca
     1501 attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag aaacgaaaca
     1561 gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat tgaagcctca
     1621 ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac tgtgacaaaa
     1681 gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt cttcggaaat
     1741 aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
     1801 agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt gctgctttta
     1861 gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt ttcagcaagc
     1921 gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc aatttttctg
     1981 tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg atttccattt
     2041 tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt ctgcggtagt
     2101 tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc tcgcgcagat
     2161 tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat tcttgtttgc
     2221 ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc aagaaggttc
     2281 ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt tctgtcaaat
     2341 ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta ggagatactt
     2401 gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg ataatctctg
     2461 cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag cttgcttctg
     2521 acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga ttgattctca
     2581 ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc catcctgctt
     2641 ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc gtaacttttg
     2701 tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca atcatttgat
     2761 agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca gttggcaaaa
     2821 gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg acgatggctc
     2881 cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc aatcgttctt
     2941 tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga taagtaacga
     3001 tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca gaatagccat
     3061 agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc gcagattccg
     3121 tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc aattgaacaa
     3181 gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc attttggctt
     3241 gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac tgctcgattt
     3301 tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct gctgataaat
     3361 tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc cagtccgctt
     3421 ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt cttagttgct
     3481 tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc ttcactggtt
     3541 tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct cttccggcat
     3601 ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg attgctttta
     3661 attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc attggcaacg
     3721 tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc aatcctaata
     3781 aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt ttgtgctttt
     3841 gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc gctagaatta
     3901 gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt tttcaacaac
     3961 gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg ctcatctccg
     4021 tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata attttgatgg
     4081 atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc gaatgtttct
     4141 tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt gtccccgaac
     4201 atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga ctcatcttag
     4261 tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta atgaacatct
     4321 taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag ttattgatca
     4381 tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat cctaaaaaac
     4441 gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga actttttctt
     4501 ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt tcatggattc
     4561 catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca tacactgctt
     4621 gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct tcctgaccac
     4681 tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt ttcgctgtta
     4741 gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga gccttgatat
     4801 ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct tctgctagtt
     4861 ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt tccatgtttc
     4921 ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag agaaaaaaga
     4981 gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga tgaaaatttt
     5041 cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag gaaaagagaa
     5101 acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg tatcggattt
     5161 agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta tagtacgtca
     5221 caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac tacgcttatc
     5281 tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct gttgcgtgct
     5341 tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt gtatcaatta
     5401 gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc cactgccctt
     5461 gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt agcaactggt
     5521 tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc agcgtttggc
     5581 tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt gttgagtctg
     5641 tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc tgccaaacag
     5701 attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac aacgatgatc
     5761 atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg ccaattgctg
     5821 catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc tgggattgcc
     5881 actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag tgaaagaata
     5941 cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt cgtcacgaat
     6001 gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg tctgctccct
     6061 gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg gatcttcagt
     6121 tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg ctccagtgtt
     6181 tccagtgcat ttggttatcg cggcgtcttt ctttcgactt ctcttcttgt tttggtcaac
     6241 ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc agaagaaaaa
     6301 gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata agcgtaaatg
     6361 aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt ttaggcctgt
     6421 tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt tttacaacag
     6481 taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa tagtactcct
     6541 gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc taatttaatg
     6601 aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt ggctacccat
     6661 tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa tattttttct
     6721 ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca aatcatcgtg
     6781 tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt ccagccaata
     6841 cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc tttttcatag
     6901 acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac ttcatctatc
     6961 aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt tttccgatct
     7021 agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt ttcaggtttg
     7081 actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt caaatgaaca
     7141 aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata agtaggaagc
     7201 atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag attagcacca
     7261 gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag agaagcgact
     7321 tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc gtttttgcgt
     7381 ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc taatgtcaat
     7441 gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt atttagccat
     7501 tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct tgatccagcc
     7561 tacagcaagc aacccgattg aaagcagtgc ggccacacaa atcagcccaa tcattacttt
     7621 ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga agcaaaaacc
     7681 aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa tgatgcccat
     7741 caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc cttcttttaa
     7801 agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg ccgctgtaca
     7861 taaagaatag gcaaattgat aggcataatc agtaactaag aaagtcaata agaatagatt
     7921 agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat tcgtttttcc
     7981 ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg ctgggagcat
     8041 cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga tcagcgctgc
     8101 tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg aaatagttgc
     8161 taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat agataaacaa
     8221 taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct tcgcgcggtt
     8281 ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca tcaaacaacc
     8341 tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat tatcagatac
     8401 gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata caaatattaa
     8461 aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga cgctcgctcc
     8521 ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg caaataaaat
     8581 agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg cgctcatcag
     8641 catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc aaccactgat
     8701 gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac catctagatc
     8761 tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac caatcccaac
     8821 gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat cacttgtgat
     8881 cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc cccatttgct
     8941 aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg aacaaatcac
     9001 ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc aactttattc
     9061 atattattgg atattatgaa ctttttacac aagtatttca agtataaaat gaataaaaat
     9121 taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc ttttgttagc
     9181 catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt tgtttcttga
     9241 tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa tacaactgct
     9301 tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg attatcatcc
     9361 aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc tgtacacttg
     9421 aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc caagcttgtg
     9481 gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt cgctagatct
     9541 tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc tagtccttga
     9601 cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc accatcaaga
     9661 gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt gaagttcttt
     9721 tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag gcctgcgcgt
     9781 tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat cgtttttgaa
     9841 agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt gtctactcca
     9901 cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg tccagtagct
     9961 acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt gatttctttg
    10021 ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag gaaatattca
    10081 aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat cccgatttga
    10141 gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc gttttcgtcc
    10201 gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc ctttaacaaa
    10261 agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg tgttttgctg
    10321 ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac gagttgaagg
    10381 tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca tcccttaatt
    10441 atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat gatagtcaac
    10501 caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc ataaaaaggg
    10561 ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt ttcaaaattg
    10621 cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag atgttatgag
    10681 ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag atacatgaat
    10741 tactttatca gtgatatgca ctttttccat gaacgcttat taggaaaaaa cgactttgct
    10801 ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag ctggaatgca
    10861 gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca tccgcaatat
    10921 gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac aatccacttg
    10981 atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa tgatcctagg
    11041 cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt taaattcgac
    11101 catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga cactatccgc
    11161 aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt caatgtaggc
    11221 gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac tccgttatct
    11281 gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc gtgaaaaaac
    11341 tgccctatat caagtattaa acaaataaag ataattactc atatttttca tttgagtagg
    11401 cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt ctgtcacaac
    11461 tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt tttctgtaat
    11521 tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca taataaaatc
    11581 ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa tggtcctgca
    11641 aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc taagacacga
    11701 cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt attgaaatat
    11761 ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc ttgactatcg
    11821 tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc tataataata
    11881 ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc taagagcatt
    11941 ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc aaagtaatct
    12001 agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac aaatgcacca
    12061 ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc aaattttgca
    12121 tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg gatcttcaca
    12181 aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat aaggtaattg
    12241 acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa attcgctgat
    12301 tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac gattgtcggc
    12361 ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat aaacaaagac
    12421 acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc taaaataagc
    12481 gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc ccagcgatcc
    12541 actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag taaagtagca
    12601 aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat cgcatattgg
    12661 acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa ataatttctc
    12721 ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct tttctttttc
    12781 attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa aaaatacctt
    12841 tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa taaatcagca
    12901 aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt
    12961 cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg tctttttata
    13021 tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc catcagaaaa
    13081 taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac tgctttcaat
    13141 ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac agtgattttt
    13201 aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg
    13261 cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc atcaggatgc
    13321 aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc catgattttc
    13381 acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt actaggtttt
    13441 tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat ataagaatga
    13501 cttcactagt tattttttga cagcacgaac taattgatca aggaaatact ggatgtcgtc
    13561 ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg gtgtatcttc
    13621 tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac aagctgaacc
    13681 agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat ttgcttcgcc
    13741 aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat ttacttgata
    13801 agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt tatatttgtt
    13861 gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca taccccagat
    13921 ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa
    13981 tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg gcccattgat
    14041 tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga tcgtttggtt
    14101 tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta aaagttcacc
    14161 gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca cagagaccaa
    14221 gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc ctttttcatc
    14281 tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg tattaagaac
    14341 agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac gcgagaacgc
    14401 tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga tgatctcgtg
    14461 aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc
    14521 gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca tgattgccgt
    14581 catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca gataaatagt
    14641 tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata aaatagcgaa
    14701 caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag aaaaaaggag
    14761 ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac aacttctttc
    14821 cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg actcatcggt
    14881 gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt aacgattgtt
    14941 aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca aatatctttg
    15001 attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg tgacgcacag
    15061 gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc aagcgttgct
    15121 cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc accgatcaca
    15181 taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt gctgttcaaa
    15241 tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac aactacgatg
    15301 tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat cgtaaataaa
    15361 ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc taaagtcagt
    15421 actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt gatcggttca
    15481 tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac gacattgatc
    15541 gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat atagtaatca
    15601 ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat actttcttcg
    15661 atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc taattctgtt
    15721 ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact aaaaatcttc
    15781 aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct ctattcttcg
    15841 atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt aaggaagtga
    15901 aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc agttgtcgtg
    15961 tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg
    16021 attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt tgccttcacg
    16081 tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac gctcatgatt
    16141 gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag
    16201 tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt
    16261 tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat aataggcaag
    16321 gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc atttcttata
    16381 cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct ttcctgacct
    16441 tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag ataactcgat
    16501 tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat aagtatattt
    16561 tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac tttgatcttc
    16621 aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct gagtgctggc
    16681 taatttttta atttttttat ctactttgaa atataaaggt ttatccacta cttgattcag
    16741 ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa atcagtttga
    16801 ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt gtaagataat
    16861 gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt gaaacaagat
    16921 ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc agataaacca
    16981 gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat gggagaaaca
    17041 gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca
    17101 tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca accgcttcaa
    17161 cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa gcaatttcca
    17221 gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc agatatgaag
    17281 aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc agataagacg
    17341 tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt tgatatggct
    17401 gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa
    17461 gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga aaacgcagat
    17521 tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac agataaactg
    17581 gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt gatcgtaact
    17641 gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt tccgttattc
    17701 aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc agaagaattc
    17761 cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag
    17821 aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg cgattactac
    17881 ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg
    17941 atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc aacaaaagaa
    18001 aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga taagatccca
    18061 gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt gctttcaaat
    18121 actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa caaaccagtg
    18181 gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca tccatttcgg
    18241 aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct agaacaatca
    18301 agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc ccatgcattt
    18361 gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg gacagaagaa
    18421 gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga tggtctgcct
    18481 tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc tgatgcaggc
    18541 ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat cgaggaattc
    18601 tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca acaactttta
    18661 ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt
    18721 gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct agcgccagaa
    18781 aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa
    18841 ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt ttcgaagaag
    18901 ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt caagtagtaa
    18961 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta ctaccgagaa
    19021 actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt
    19081 agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    19141 gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct gcatcaagta
    19201 ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga tagaaggaag
    19261 tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa ttgttttaca
    19321 tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa caactacacc
    19381 gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc ccgtttttgg
    19441 gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat gagaaggttt
    19501 tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    19561 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    19621 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    19681 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    19741 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    19801 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    19861 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    19921 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagacgg
    19981 tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    20041 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    20101 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    20161 atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    20221 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    20281 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    20341 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    20401 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    20461 actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga atccattacc
    20521 gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg agtttttgat
    20581 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    20641 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    20701 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    20761 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    20821 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    20881 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    20941 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    21001 tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa cgccttttgg
    21061 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    21121 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    21181 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    21241 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    21301 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    21361 atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca cctctcctgt
    21421 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    21481 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    21541 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    21601 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    21661 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    21721 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    21781 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    21841 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    21901 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    21961 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    22021 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    22081 aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    22141 cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttagg
    22201 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    22261 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    22321 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    22381 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    22441 ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    22501 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    22561 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    22621 gtgtattcct cccgtaacaa attagaaagc gtttacttaa agtattacct aatttatttt
    22681 tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa aaatataact
    22741 taagttgttg ataataaaga gatttattaa cgtaaaaaga ataagttttt ttaaaataac
    22801 gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc tcttctttta ttattttgtg
    22861 ctttttattt tatcaaatca ctttgttttt ttataaaatt tctgcgccta gtgtggactc
    22921 aaaatgtctc aatgcccatt catgtccaac gggatcgaaa cttgccacgg aatctttgaa
    22981 aatatggagt ttgtatccta gattatacgc atcgactgct gtatgcaaca cacagatatc
    23041 tgtacatacg ccggtcaaat aaatatctgt gatctggcgt tctcgcaaac ggatgtctag
    23101 atctgttcca ctaaaagcgg aataatgccg tttgtctatc caataaacat tttcctcttg
    23161 ctcatagtct tggtataaac tttttaaaga gccgtacaat tcccgtccac ccgttcctat
    23221 cacattatgc ggaggaaata agcggttctc cggatgaaag gaatcttttg gatcatgcgc
    23281 atcaatggca aaaacgacaa aatccttttg atcaataaac ttctttgtat gagcagtcag
    23341 ctttttttca attacttgtc ctgctgtccc agtagtcagc tttccatcct ctgcaacaaa
    23401 atcatatgtg tagtcaatcg agatcaatgc gttcatctta gtcctcctta tacgagatgt
    23461 ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg cgtcttcgat aaattcgtca
    23521 aagctttgtg tcgccgagtg atctgctgtg tcgctcattg cacgtacgat caaaaatggg
    23581 atattgaact gacgagctgt ttgtccaaca gcggctcctt ccatttcgca agctaatgct
    23641 tcagggaaat tcgttaagat ttctttgatt ttatctggcg agtcgacaaa tgtatcacct
    23701 gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt ttgctgcttt aaccatttca
    23761 ctgcgcaaat atgtgcttgc ttcataatat agaggcattc ctggtaattg tcctgggttg
    23821 tagccaaatc ctgttgcatc tgcatcaaaa taagctactt tgtctgatat aacgatgtca
    23881 cctacttgta agccttcacc gattccgcca gctgaacctg tattgatcac catgttcacg
    23941 ccgtattgtt ggatcaacag acttgtggta atagatgcta agacttttcc tataccggaa
    24001 cgtacgacga tcacttcgtg gttacctaat gaacctgaaa taaataaagc gcctgcgcgt
    24061 tcccatgata atggttcgct taggttctct ctcaaaattt ttacttcttc ttccattgcg
    24121 ccgataatac cgattttcat ctttttaatt ccttctttct atataaatgc gattgctaaa
    24181 aaaaccacac ataacattag gataacaata ataagagatt tcatcaaaaa agagttccat
    24241 ttggtcgtct tttcccgttc gctgatcctt gttttcgtga ttggtttatt ctttttgctt
    24301 tctttacgat aaaagctggc aatctttttt tcttcttgct gataagctgt ttctgctttt
    24361 cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc gcttgcgaag ttcgcttcgc
    24421 gtaataagcg gtcctttggc cataagccga tccctctact ttcctttggt caatagttcc
    24481 cagtattgaa tcgcataaat cgtctttgca tcacaaatca actgatcttt catcgcttgt
    24541 tgcgcctctt caagagttag atgatacaac tccagtactt cgtcttcatc ttgtgctaaa
    24601 ggattctcga ccttctctac cccttgtgca tgataaatat gaaggacttc atttgcaaaa
    24661 cctggtgaaa gatacatcga agtaagatgg ctcagcgact tcgcacgata gccagtttct
    24721 tcttctaatt ctctagctgc tgtcatttcg ggattttgtc cttctcctgg atcgattttt
    24781 ccagctggaa tctccaaaat cactttttct aaaggttttc gaaattgttt gacaagaagc
    24841 agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc caggatgaaa taccagttct
    24901 ctcttcgaag ttcctccatc tggcaaacga acttcgtcta cagcaacatc aataattttt
    24961 ccgctataga tttctttgcg actgattgtt ttttcttcaa attgctcatt gttcagcata
    25021 tcttctcctg ctttctttgt aatcataact gctttttttt catttttcaa tttttctcaa
    25081 aaactcctta ttagtttacc atagataaac cttagatttt ctctaaatat agaaaatcct
    25141 tctttagtcc gatactcttt ctagtagtcc gtatgctaaa ataagtatgt aatcgaataa
    25201 cgaaaagaat tcaatactca acgataaatg acatggaggg tttattatga taaaacgaaa
    25261 ttggccgtgg cttctagcat tggtcttgct atttctcttt gtccgaaaca atagtttttc
    25321 ttttgttcta ggacttttat tgataggtgt agttttagtt ttgtggggac tctttggttc
    25381 gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg actgacgaac ttgaaactca
    25441 ctatgaaaaa agcggtatga cagcgaatga aatttcattt tttcgacaaa caatgaatca
    25501 aacaaaaaat gagatcaatc aattgcaaat gaatatgcag cagacagcca aacttaaagc
    25561 aatcgatctc cgccatgatc cagtcaaagc agcgaaagct ttattcaaag aattggtgaa
    25621 agaaccaaac cgactgcatg aagcaagtca gtttctttat acgcatctgc cgaatctagt
    25681 tgatttgaca aataagtata atgagatcaa tgaccatgag atcaaaaaca aacagaccta
    25741 tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg tcagctttaa tcgcacaaga
    25801 ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac gtagagatat ctgttgcgaa
    25861 acagagctta aagcgtgata ataaatatga accagaacaa aaggattaac tcttttgttc
    25921 ataaaagaag actcggaaca ttcagatgat gtctggctgt ttcgagtact ttttctaaag
    25981 tagagacatt catgtaagaa tcgagaacag attcaacaag gaggaatttt ttatggatca
    26041 taaaccgact gaaacaaaag atgttacacc agttaacgat acacttgaag atttattgaa
    26101 caacccgttt tcaactccaa cagatacgct gaccacttca caacaagcgg agattgatca
    26161 gctccaagag caacagacag ctgctcgttt aattgacaaa ctaccggcgg aacgccaaga
    26221 acaagctaaa cagctagcag caaaaatcga tgctaatgat gcacagtctg tcatcagcta
    26281 cggatcggct gcccaagcaa aattaagtga attctcacaa tcgatgttga atcatgtgca
    26341 agcacaagat attggtcctg taggagattc cttaactgaa ctgatgtatc gtctccaaga
    26401 agccaatcct gacgaactgc gtgccggaga agggaacatc ttccagcgtg tcttcgggaa
    26461 ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa aagattggtg cacaaattga
    26521 caagatttca gtgaaattag ataaagaaaa agacggtctg ctaaaagata atctgatgtt
    26581 agaacagctt taccagaaaa acaaagacta ctttgatgca ctgaatattt atatcgctgc
    26641 tggagaattg aaaatggaag aacttcaaac aacgatcatt ccagaagcga tgaaaagagc
    26701 agaagaaact ggcgatcaga tggatgttca gattgccaat gattacacgc aattcctaga
    26761 tcgtctggat aaacgtacgc atgatcttcg cttagctaga cagatcacga tccagcaagc
    26821 accacaaatc cgtttgatcc aaaacacaaa tcaggccttg gctgaaaaga tccaagcatc
    26881 tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg atcgcattga ccttgcttcg
    26941 tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa acaacaaacg acttattgaa
    27001 gaaaaattca gaaatgctga aaatctcagc catcgaaaca gcgaaagaaa atgaacgtgg
    27061 aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat ttgatcgaaa caatccaaga
    27121 gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt catgcagaag tagagcttgg
    27181 acacatggaa gaagatctga aacaaaaact gttggattta acccaataga tcacctttcg
    27241 cttgttacta aaacaaacgc ccaacaacag tttattacaa ctgttgatgg gcgtttttct
    27301 tatctttctt ctaacttctc cattggagtc tatttctcat tcatcttgct gtgtccatag
    27361 ccatagccaa aataaatgat cagtccaata accattacga taccgaacac gatccatgtc
    27421 acagtttgca gacgaagcat caatacaata caagtcaaaa tggagacgat tggcaatagc
    27481 ggaacgaatg gcactttgaa ttctccagct tttggtttgc caaacatttt tctcaacttc
    27541 agtaagccta gactaacaag catcaaatag gcgagcgcca tgatattcgt tagttccgct
    27601 aatacattca atgggaaaaa tccggcaaag aatacagctg ccacaccagc ggcataagtc
    27661 gcttttttcg gtgtacgatg cttttgatcg atttctgtca taaacttagg aagtaagcca
    27721 tccttgctga cagcaaacag taaacgagca agtgaataca tcatcgagat cgttaccgtc
    27781 agtagcgtta aaattgcccc tacagcgatc accgcgccca ctgttccatg tcctacatac
    27841 ctcattgcaa aagccactgg gtcattgact cctagttcag tatacggaac gattcctgtc
    27901 aagatcagcg tcacgatgat gtaaaggaca gtagcaatca gtatcgaacc aatgattcct
    27961 cttggcacat ctttttgcgg gtttttgact tcctcggctg ccattgcaac ggcatcaaat
    28021 cccaagaaag caaaaaacac aagagctgca ccatctagca caccggaaaa accaaaaggc
    28081 atgaatggct gccagttatc aggtttaacg aaaaatattc ctacaatgat aaacaacgcg
    28141 atgataccaa atttgacata taccatggca ttattcaaac gtaatgcttt cttggcttca
    28201 agcgacacga tgtaagtgac gaatatcact acgagcaccg caatcaagtc aatgtatgta
    28261 ccattttccg gattgtaccc gccagttaat gcttgtggaa gttcggcccc taaacttttc
    28321 aaaaaacctt gcatatagcc agaccatccg gaagcaacag aggaaaccgc tagtaaaaat
    28381 tccccgatca acaaccaccc tgtcagccag gcagcaaatt caccaaatac aacatacaga
    28441 taggcatatg gcccaccaat cactggcact cgcgaagcaa attctgcgaa acttagtcca
    28501 gacaaaatga caacgattgc agctaagaca aatgaaagtg acagtgctgg accagcattt
    28561 tgattggccg caacccctgt caccacaaat attcccgtac cgatgatcgc accaattcca
    28621 agcatgatca aatcagacgt ttttagttct tttttcatct cactcgtatg attgagattg
    28681 atctctttct tacgaaacaa atccattgaa gttcctcccc attttaggtt ggaaaacagc
    28741 gattaaactg ttttcatata ccctaaaagg gataccacct aaaatgacta aaaggcaacc
    28801 aacaataaca taaatgagct cttttttcgt ttttctttcg ccaaggatga aaatcccacc
    28861 taaagtagag ataatgatcc ccatttgtga aagtgagaag ccaacagcta aaccaagtga
    28921 tttgactgtt agaagcatgc agatgtttcc taagccccat aataatccac agatcatgtt
    28981 tttccacaca aactgatcga ctttaacttt acggaaagca aagaagcttg cgcctaagat
    29041 cattccgata ctttgaggta agataattga catcgcatcc aaattcgccc agttgacgat
    29101 gatggtatat acaccataac caatcgtaga gaagatcaat gctctaaaac ccttaccaaa
    29161 atcaagcatt ttattatctg tatctatttt tccttcgtca tcttgtcggg cagtcaaata
    29221 cgcaccgctt acaagaagag ctaaagcaat aataccgtat acataatctt tcgtttgtgt
    29281 ccattcatgg aagaaaacgg ctcccgcaat cgtattcaaa attaattgaa aaccagtaga
    29341 caatggtagc cctacagaaa cacccatgta cttcattcca tggaactgtc cattttgtcc
    29401 aacactccaa gctaagccgg ataaaaatcc gatcaagaaa atccaagggg tgattacagg
    29461 actaacaacg aaaaagacaa ctaaagaaaa cagaaatgca ccgatcgtca ttcctagtgt
    29521 ttgttgattg gcatcgccac caattttacc acttactaaa ccaatactac cccatgccaa
    29581 catagggact aatgctatta aaatttccat aaccaatctc cttttatttc acatgataag
    29641 aaacttatca gcgaaaacgt taacaacaca agcacttttt ttcgtttcta acgattttct
    29701 aacgtttttc attataaaaa tttaagattg ggaaaaataa agtcattgtt gtcccttttc
    29761 cttcagttga ttcagccgtc aaatggatac ctaatttttc ggccagattt tttgctaaat
    29821 aaagtcctaa tcctgttgaa tgtgttttgc taagtcgacc atttctccca gtaaatccct
    29881 tatcaaagat ccgtttcaag tcttccgctg ggataccgat ccctgaatct ttaactgaaa
    29941 ggctgactcc ttgcgcttcc ttttctatgc tcacaatgat gtttccgtga tccggcgtat
    30001 atttgatggc attactaagc aattggttga agataaaagc gatccattta gcatcggtca
    30061 aaacagtatg atcctcacca acgatctcgt agcgaatatt tttttggata aaataatttg
    30121 cctgactgcg tatcacaggc tgaatgattc cttttagtcc atattcttgg atgaggtagt
    30181 cccgcgagaa actgtcgagt cttgcataat acaaaacttg ttctacgtat tcatcgattt
    30241 ttgataattc attttctagt aatgtatact tttgatcgtc aatatcgaac tcgatcgaac
    30301 gaactagcaa tttagaagcg gaaagtggca ctttgatttc atggacccat gagtcaatat
    30361 aatctttttg gtcttgttga ttactgattg ctgattgcat tacttcttgg tgttcacgga
    30421 tcagctgatt gatatattct tctaccagtt tttcttcttc tgtcctccca ccactcaaat
    30481 aattttgcaa aggggaagtt ttttgtatgt cggctaattt tccccaccat cttctcttgc
    30541 tcaagtaacc acccagcaga taaaaaatca gaaagacgcc ctcaatcaaa gctaaataag
    30601 caattgtgct caaatcaact ttgatgtttg gcgccagcca catcacaaag atcgtcaatg
    30661 caataaaaaa cagccatccc aagatcaatg tccactgatc tttcaaatat ttaaaaaaat
    30721 tcatcttaac cgctcatcct ttcagggaac gatatatccc tgtcctactt ttgtttcgat
    30781 atatccttgg atacctgcct gttcgatttt tcggcgtaac cgattgatgt tgactgtcaa
    30841 tgtattgtca tctacaaatc gttcgtcatc ccacagtgct cgcagcaatt tttcccgact
    30901 taagatcttt ccattgtgct tcatcaaaat aaataataga cgatattcat ttttgctcaa
    30961 atcaatgatc tctccgttga tttccatact tccgttgtca acattcaacg taatgccatt
    31021 gtggctcatc atttcactag ataattctgt gtagttgtaa gaacggcgaa gtaatgcatt
    31081 gatttttgca atcagtacat cgatttggaa atgttttgtc acaaaatcat ctgcccccat
    31141 gttcatagcc atgatcatat ccatattcgt attcctgctg gagataaaaa tgatcggtac
    31201 tttcgatact tcacgtattt tttgacacca ataatagcca tccaaaacgg gaagattaat
    31261 atctagtaat acaagctgtg gttcttctct ttcaaagtct gagaacactt gattgaaatc
    31321 ggtcgttcca aaggtttcaa attgccattt ctcaagttcc tccatgatca attgtcgaat
    31381 gatctcttcg tcttcgacta ccatgatttt tgccataaaa aatccctcca tctttcttct
    31441 tgctactaca atatcaaaga agcccttgtg aaacaagttg gcttacctgg aaaatgtcat
    31501 tttagcaaac gttaaaaaaa actggaaata tgcgatttaa tcgcgtttgt ctcttccaag
    31561 cagcttaaat ttattatgtt attcttaata attggtctat tatctgttat ttttctttcg
    31621 ttgtttttgt cttttaaatt ttcgataaca ccaataaccg aaaagcgtta gcactagcaa
    31681 tatacctaga aggagtataa gtaatcgata aagatggtat ttttttgtct gttctatctt
    31741 tgaagagact tcttctgtaa agggaactcg tcttcctgtc actagtaatc ggtgagtgtt
    31801 cacggtgtaa ggtgtacaag tgataagtgt gactagatcc tgcttttctc taattgctaa
    31861 tgtatttgtt tttgttggaa ggacaacaat tttctcaacg acttcataag cgagcatccg
    31921 accatacact tcaagataga atcggtcatc ttgctccatt tcttcaagat ccgtaaagag
    31981 ttttttctca gcaataccgc tatgggcggt aatcacggaa tgtgtactct ctcctccagt
    32041 tggaaaagag gtgccttgca ggactgtcgc tcctctatct aacaaaagat cattcgtttc
    32101 atcaaataaa ggcaagctaa cattgatttt cggaatatag atggctccga tcatatgttg
    32161 ttcgtaatat tcttttcctg gattttggac atttctaacc gcttgctcaa aaggatcttt
    32221 gacttgtccc attcctggga ttactgatgt atgagcaagc gtctgatttt tcttttcatg
    32281 cactgctaat tgttgctcat gtttttcttc tttatcgcgt tcaagctgct tttgataatt
    32341 ctcgatcctt ctttgatcca aataattgct gagagcatct gctaaaaatg gatatgtaaa
    32401 aactgcagct ccggcaagaa acatcactgc cataaataat tgtaataaaa gactgatttg
    32461 ggtttgaggt ctattaccta ttttcttttt cattttcttc accttcttat ttaaaaaaac
    32521 tgcagcaacc tttataaaac cgattgctgc agcttatttt tgttgcttat acttcagact
    32581 tcattttaga tttacggtac cagctgtacg ctccaatcat caaacttatt ccgattagta
    32641 agaatgccaa gagcccgttc ccaccagtag caggaagtga cccgcgtttc atattcggta
    32701 ctctttctgg ccctggattt tctactccta cgatctgaat ttcttcatta tagcttccat
    32761 aagagatgat aaattcagta aaggctgcct cacctgttgg aagtacataa ccttctggcg
    32821 ccatggtctc tttcatttga taggttccat aatctaaccc ttgaacctca aagtatccat
    32881 ttccatctgc gacaaattct gttgcttgtc cgcttgttgc ccactcaatt ctatctgctc
    32941 ctgattcata aacagctaaa ggcgactccc ctttataaaa tattgcgtat tcagaacggt
    33001 cttcattcca caattcgaat cttgcatctt taagcaattc actgcttgat gcatcatatt
    33061 tttcaaactt tcttccacct gttgtgactt tctctggcgg ctctactcct tcttcataat
    33121 caaattcatc atttcgtccg atttcaataa ccgctgtgtt gttatggaaa tcatccgctt
    33181 ctagttctgt ggaaaccttc aaattatacg tgatcgttaa atctcctcca cgtgcatctg
    33241 ctaatctacc taaagtatct actttggcta ctccattttc ttctgtcaaa atcgtcacga
    33301 caaacccgtt gcttactact tctactatat aatcttgtcc ttttgttaaa atcgtctcgc
    33361 cggctcgcac ttctatttcc tgatcataat aagttagacc aactgtaggc gtatctgtga
    33421 ttttgtaatt tttgataaca gcgcttccgt tttcaaggac agaatcgatg aaataaggaa
    33481 taggtgctgt gatcgtgtaa gaagccgttt ttcctctttc tagatcaata taagaaatcg
    33541 tttcttgttc tccagcttca ttaataatcg ttacttgtct aaggtcgctt tcctctacat
    33601 tcatctgttt atctgcttct ctgatttcgt ttttcggata caaatgcaca tctgtattgt
    33661 atgtgtcttt ccatgtagaa ccatcccaca cgccatccac catatcaggc atcatcactg
    33721 gcatcataac aaccattgga gacgcgattc tggaaatatg agctggcgaa taagtttcta
    33781 agaaaagata gactttatct ctagaagaag gtgcttcttc cgtcacttgg acggtagaga
    33841 ataccgcttc tccagcttca ttcgttgttt gtttgtcaat acttgtcagt cgatatttta
    33901 aaaaccaact ttctgtgtgc cgtttttgaa tccattcaat cgcttcggca gaattaagac
    33961 cgtcttctcg ttccggtgtt aaaggattat ctcgaatcaa atcgtaatat acttccgtta
    34021 cgtcaaacaa atcaaaatcg actcctggaa tattttcttc accaaaatcc gtagaaacca
    34081 atccgctatt cggtcgttct tccggaacag atgagaaacc ttttttgtgt aatgtaatcg
    34141 tcacttcact tggtttttgt gcgacttctt cggctttgac tagttttccg ttcccgaaaa
    34201 tccctattcc cgcagtaacg agtaacagta cactcattcc cgtgacaatc atttttttat
    34261 tcattttttt ctccccgttc tttttttatt aataaaacag cacctaacaa taaaagaatt
    34321 cctagtaaag aaatcaacgt tcttgcttca ttcgtttgcg ggaatacgga ccattttcct
    34381 gattgacctg gattgcttgg accactcggc tctttcggtt tgtccgttgt ttcttttacg
    34441 gtctcgttat aaacacgtgg tgttgcggat tcataggcag agactggaac tttcccggat
    34501 tctaattcag ccatctcctg tccgttaact actacatatt gtggttggcc ttttgcatcc
    34561 acccaaaatt cagggatgat gacctcgatt ctcttacttg cttcatccat ctcgtaacct
    34621 tccacacctt ttaattcttc aaaataatag gtgccagaag gcaagaaacg ttgtcctgtc
    34681 gtaacaaggc cctctttatc cgaaatgaat ttgcttacat ttttgtcatt caaaggatca
    34741 ttgtctgctg gtttgatcca ttgatttttc aagtcattag caggagccat atctaaataa
    34801 tatttccccc cttctatcat ctgatataga gcaaaaacag caccttctaa tggttttcct
    34861 ttttcagttg ttcctctttg acgtccatac ttgaagaagt atggatctct tagataaccg
    34921 acatttttag gatagatatg aatctcttgc agttcctcgg ttgattctgt cgggtgataa
    34981 attggcaaaa tagcagcaat tgggatagct gtctgatcga tatcaacatc caatccaact
    35041 tctggatcaa tcgattcttc gaaaatcaaa taaactgcat cccgatcttg gtttttctta
    35101 ggtgctttga tacgtgcaat cccgtctcct aatccgccaa ccgtatcttt cccagttgtt
    35161 accgaagtcc ctatttggac aagcctttct tctgtgatta gctgacggat attgtttctg
    35221 ttcgtttcag cgatttgctg gacgaattct ttaggagtca tgttttcagc agcttttttt
    35281 tcatgataat aatcggtcat gtcgtaaatg gcaaatgtcg ctccatttag tggcaccgtc
    35341 tgtgaaatga tatctgctgt ttcccctgct tcctcagaga tagccaagcc atcattttca
    35401 tggtattcaa attgatcgtt ataatcgata tctcgaatca tccgtttatg caacacgaat
    35461 tccacgacat cttcccctga ttcttctgcc gacatcgcat gtggaagaag gactgctgca
    35521 agcggtagta aaacaagtaa ttgaagcatc aaacacaaca gctttttcat taccttgctc
    35581 cctccttttt agattgtctg acaaacaaac cataggctgc tcctgcaagc gccatgaaga
    35641 atgcagcaag caggatatag aataatcgtc cggatcctcc tgtagcaggc aacggatttt
    35701 caggatcgtt cccgacacta agctgtaatc tgattcgatt tgtctccaaa agttcatatt
    35761 ctaactcttg ctgtagatca ggcgtctctg cttcttcgtt tggataatac gaaatctcaa
    35821 cttttagtgt acccgcttct tttcctggaa ctacccgatc attttctatg tcaggttctt
    35881 ctcgataact aatttctaaa ataaagtaac ctggaagttt tctatagctg tcaggtgact
    35941 tcacttcctt gatccgatag accccttcca acaagtctga agcattgaat agggaagaat
    36001 cgtttggatc tggtgccaag cctccctcga tgatttcata ctctcctgca ctattttgtt
    36061 tctcaattga aaattctgcg ccttcaagac gtcggctatt catactgtca attttcaaaa
    36121 gttccaaatc gattggcgct agttcatctt ctaaggttac ttgtagtaca ccatcgatga
    36181 tttcatagcc ttccggcaag ggagcagttt cgtcttcgat gaccgtatct tcaatgataa
    36241 acttaccttc ttcattcagt gcaaactgga acacttgatc agatagccga tacccatttg
    36301 gtgcgacaga ttccgagacc tcatattcac caatagacag atgcagaggt tggtcgtaat
    36361 ttaaatcgac atacttttct actcctacgg cacgagaata gaagtatccg atcccaggca
    36421 aacgtttcga ttcttctggt tctaacggat taccagtgta tgctcgatac agcgggaagg
    36481 aagaatcccc cactttcctg atatcgaaac ctgcaccatc taatgtatgg ccttcatggt
    36541 ctaattttct aactcggatc tcccgataat caaacgtatt gtaagcagtg aatgctaccc
    36601 ataaacgatc ctcttcatct gttgtatacg tgagatattg ccaattttct tcacctgttt
    36661 gcttgagttg gatagtccct atagcattat cgtaaagtcg caagatccat gtgtcatttt
    36721 catcaggttc tttgaaacct tctgggttct ggctctcaat gattttgtat tctgcatagt
    36781 tggtagtttc ttcactatcc ttataaacaa atgaatctgg ctctccgatt ggatgaataa
    36841 ctttctcacc atccacgatt acatatttcc cgtcttcatc tactgaatag aacgtgagtc
    36901 tccctttctc ttcctctact tcgttcacac cagaaagccc tttcgctact ggatatccga
    36961 tttccagtcc gttaccatct gtttcataaa gttcaaactc tgcgccattg attggcatat
    37021 tactgccttc aattagttta ttgatattca tgtggattgg cttgaattca tttcgcattt
    37081 ccagtttgac atacaactca tcatactctg tgccttctat gttaggctct tgtacaacag
    37141 aaagcttgtg atattctcct tcataatagg aattcggatc tttaccttcc ggtccgccga
    37201 ctctcgaacc agatgtatat tcatctacaa gctcgtagtg acctaacatc tcatcttcgt
    37261 tggctgcata ttttttgatt tggaattgat acgtctcatc tactaactga taacgtggtg
    37321 gtccagcgat ctctctgatc caaaatatgt cgctgactgc tccagtttca tctcctaaaa
    37381 tcggcatctt cgtttcaaag atcgctattc cgtccgtggt agttttactt gtttcgattg
    37441 gttcggcttc cccactctct ggattttggt catataatgc aaattcgact ccagccaacg
    37501 gctcgccatt ttgacccttc ttgctgactt ggaaattacg gcctttatgt tcgtaacgaa
    37561 tggaagaaga tgggaaatac atccgtccag tagtgatatc attctcataa tcctccaggt
    37621 tctgaatata ggccatattg ttcactgtgc aaaaatttcc gtcttgagct cccgcatcaa
    37681 gttttacttg gtacttgatc ctgaccattt ccccttcacc taaagaaatc ggagaaaatt
    37741 tataagcttg gttttcccgt ccgacatacg ttgtcggagt cgccactact tctggtgggg
    37801 cttgtccatg acgttcttca tcccatattt ctggctcttg gtacttcatg ccgttttctc
    37861 ctggatctag atggtaaaac tgaatatctg ccgatctgcc agctccaaat ggtgagacat
    37921 taaaaccagt ttcatcataa agtgtggctt gctggatcgt tctcttgaag gtagaagaga
    37981 tatcctccaa ggctgtaaca atgtcattct tgttgttcgc attgtaatat cgcggtgtta
    38041 cgccatcttc ttctaaatca gcaatatttt tcaatacatt tcgtccaata gcatctagtc
    38101 gttgtctccc gctaacgttt ccatcgattc ctaaaccaat ggagaagata cttggcgggt
    38161 tctcttgata cttgtttttc agccaatgat gataagcaac tgtgttgatc gcagatgact
    38221 tttcttgcga agtaggactg ccattcgtat tgttattaga agaaccatca ccaacccagt
    38281 gagtcgcttt attatctcct tcttttacct ctccataacg atagtgtaca tttacttcat
    38341 cttctggacg gttaaagtca gatgcatagg taactggatg agtaaaccct gcattagaag
    38401 tattcccaga aaactcctca aaatttctga acaaaacgtc attatcttca gcaatcttat
    38461 cttccatcac agtccagttg ctccaagctc cattagtgct cgtacgataa cttgactgaa
    38521 tcggtgcata actgaaggtc ggtgtcccat ctcccacaac gattaggatt ttttctggat
    38581 ttctattttc tccgccattg tctttataca atgtttcata gccattttta agccctagtg
    38641 taagcggagt tcctccgatt ggtgtacgat ttaatgctgt attctcactt cccgtcaaac
    38701 gattgatatc atttgtcaat ggaaagatgt ccgaactgat ttgctcatgg ttattgatag
    38761 ctgtactatt atggtaaaaa ttcaccatac cgattcgaat atccagactc gggtcagaga
    38821 gcagatcttt actcatttcg tttactgcct caatcaacgc agcattttta gtttgactat
    38881 tggtcccagc ggttaattca ctcatactcg ctgacttatc tagaacaaaa acgatatcga
    38941 ttggactgat ttcctttttc tcgcccccga tgacatctag atagacattg taaagggttg
    39001 ttgcatcttc aggatgtaga tcagatgctg tgctgcttgg cagaacaggt tctacccatt
    39061 ttttgatgta cgccccgtta taatccaagt aactgttttc aaaattccgt tcatttcccc
    39121 aaagctgaac ggtttgagct ggaacgtttc tatcttcttc gcctgcagtt gatccattat
    39181 tagtagcata gtcgtaattt cgccagttcg ctcccccgtt tgtataatca ctatcatcga
    39241 tcaagttctc tccgtcatat ggcgagcctt tgtctccttg atagcgttca ttgctttgtg
    39301 tccaatttcc taacactttt gtatagtcat tcgttgtaaa cttcgggtag cgatgctgtt
    39361 cgttttcaac ttctccgcta ggatagatat attcataggg gtcttgcgta gctgttggcc
    39421 caagacgctc caaaataccg ttgaataact ggcgttgaat gcgctggagt gcttgaccgc
    39481 tgggtacgat tggttcgtcc agcttttcca tctcattttc ttcgctacgt tgaatttcag
    39541 cggaatcttc tgtatcagtt tcattttctt gtaattcttg gttatctatt ctttcatcaa
    39601 ccaccacttg aagaggtagt tacccttcgt tcacatcggg gatcttttct gtttcaaaaa
    39661 tcaatgtgcc ggtttctgct tcttttgaat aaacttttcc gacataccat tcttgaccat
    39721 cgatcgtctc gacttttagg tcttctccat cttcatcata ggaggataga cctgttccac
    39781 gaacgttttt tacggtacca atcccggcgg ctgccgcatc gattgctaaa cgtattctac
    39841 cttcattggc actttccttt ttttcaaaag ccagatgcca ttcaagggtt tcttcttttt
    39901 caatatactt cccttcaatt tttgcatagt cctcatctaa gaatacctca tcctcctttg
    39961 tttctgttga ctcagcagct acatccaggg tcgtcatatg atagactgac tggaaatatg
    40021 gtccaaatag caaactgaca gttactaact gcaaaagctt caattttaac cctttcacat
    40081 ccttatactc ctttcaaaaa tatttgtctt ctttcacaac aatcaacaaa acaatgccca
    40141 tctaattata atttaattta attttaattt taaatcaaat gatatccttt ttagttaaaa
    40201 aacaccaatt atacaacatt tattattaaa attaaattat aaaattttat aacgttctca
    40261 tttaacaaaa cttaagttat taagacaaat gaataaacaa ctacgctttc ctcgaaacaa
    40321 aaaaataaag cacaaatgcg catttacgca ctcatgcttt attcgtacaa ttaattcaga
    40381 taacggcagc gcataggatg ccaataacac ttcctaaaat agctcctcct aaaatgtcag
    40441 taggataatg taaaagtaaa aaaatcctcg aataagcgat caaacaagca aataaaaagg
    40501 ctaatattcc tgcaactgga cttaattcga acaacgcagc tactgataaa aaggctagcg
    40561 ctgtatgtcc tgaaggaaaa gaagaagtct tcggtttact tgtgtaaagg acaagccgac
    40621 gatttttttc ataaggtctt ttccgtcttg tcgttttttt gataaaaagc aaaccaacaa
    40681 aaaaatagat caaactgccg ataagaatgg ctagaccata ttctctagta tcaggtatca
    40741 agactaaaac agcagcaagg agcaaccaaa taaaaccacc attagagata ttactgataa
    40801 atttcaaaaa attgattttt cgactatccg ttttccgttg cttggcgaac ttgttgataa
    40861 tactatcatc gattttagca atcaaacgca acatgttatt cctccttttt aagaaccttt
    40921 tcttgcgtac gatggataaa aagcaggact tgaaaataaa acaagaaact gaaacctaat
    40981 aaagcaaaat agattggtcc tgcaaaccag aatgcgacaa gaaggatcaa cgtgcctgcc
    41041 aaatagaaaa gcgcgctttt gaaatcatta aaaaacaaga aaaatgcagt aatccaagaa
    41101 gcttcttttt gttccagttg aagcaagatt ttgtaactaa agagaagcgc gcttaataga
    41161 agcaaaaaca acgtagtata catcaatgta tagccaattc ccccacccca atagcggaaa
    41221 atctgataat cgatcaatag aagaagaaaa taaacacttg ctaaactatc ttgctttcca
    41281 taaagagaga agttctcacg aaactttttc cagaatagtg aaccgagctt tttctcttca
    41341 ttttttttgt aatgataaat catatacaga actgttcgac ttgcagttcc taatgtgaaa
    41401 acaggcaaga cgcacaggaa ccatagtagc tgtaaatgga taagacgtgg aatccattca
    41461 atgatttcta agaaataatc attggctttt ttaccaatcg atcgattcat catccttttg
    41521 aacctcctgt caaatccatc ccttcaatga aataacgttg tgcaaaaaag aacagcaaaa
    41581 tcgtcgggat caagacaagt gttgctcctg ccatcagata attccattgt gtcgttgctt
    41641 ggttctgaaa aacttgcaag ccaatctgta acgtgtattt ttcttgatct tggatatata
    41701 acagaggacc taagaaatca ttccaagctg cgttgaagga attgatcgca atggtaatca
    41761 aggcaggttt cgtcaatgga agcatcaaat gactccaaat atacaaatga ttcgctccgt
    41821 cgatttcagc agcttcgatc aattcattat tgatcgataa gtaaaattga cgcatcagaa
    41881 atatattgaa cgcattgccg aagaacgatg gaacgatcag gggcaaataa gtacctaccc
    41941 agccgatctt ggagaataat acatattgag ggatcatcgt tacaaacccc gggatcatca
    42001 tcgtagaaag aaccaaagca aacatcagct ttttcccagg aaaatcaagc ttcgcaaatc
    42061 cataagcaat aaaagaattt gaaaggacat taccgatcac tactagcaca gtgatgaata
    42121 atgtatttct tgcatagcgc caaaaaggaa aggcggcaat cgtatccaga tagttttccc
    42181 atacgatttt ttctgggaaa aaggtcggag gataacgaac gatttcttcc attggtttca
    42241 atgaagtaaa caccatccaa agcaatggaa tgatcaaaat gattcctatt actgtcatga
    42301 ggacataact tagtattttt tttgtttgcc gattcacact ggtctttttg aaataatcca
    42361 tcatttgccg tcacctccag aataatagac ccacttaggt gcaagcttca aattgacaaa
    42421 cgtcagaacc aacacgatca gaaacaggat cattgacata gccatcgcat aacccatatc
    42481 aaaagctacg aacgccttgt tccacatatg cagattataa aaaagcaaag aatttgcagg
    42541 tccgcctgtt ccatttttcg tcatgacata agcttcttga aaaatttgga aagaaccgat
    42601 cgtagaggtg atcacatcgt aaaaaataat aggagtgatt aatggcaaag taatactttt
    42661 gaactttccc caaacgcctg ctccatcgat ttctgctgat tcatataaag atctaggaac
    42721 attttgtaat gtagctaagt aaagtagcat tgctcctcca gaactccata ttttcatcaa
    42781 aatcaacgca ggtttcgtcc attgtggatc aaacagccaa gctggtccag ggatatggaa
    42841 ccagcccaga aatgtgttga tcaatcctgc agatggagaa agcagctgca tccataagat
    42901 gtagactgct actcctgata agactgccgg taaatagaaa gctgtacgga atacactgat
    42961 tcctttgatt ttttgattga gtactgtggc taaaaacaca ctgaaaatcg tcgtcagcgg
    43021 tacattgaag atgacgaaat aaacggtgtt gtataacgat ttccaaaata aatcatcgtg
    43081 aacgaacatt cttttgaaat ttgctagacc aatgaaattc atcttggatg tcaaattata
    43141 atcggtgaaa ctaccaataa ctgaaaaaag cataggccct agcataaata ccaagaaccc
    43201 gataataaaa ggcgagataa ataaataggc ccatcttgct tcttttttct ttcggataga
    43261 taaacgcttc aaattttctt gcctcctctg tacctagaca gtcaaaaatg gattattgat
    43321 tttgcttgac taagttttct actgcttttt gtgcatctgc caatccttct tttggtgatt
    43381 ttgttcctaa aagaatctgg tcaatctgtt cattcactaa tgtcgtgtaa tccggagcat
    43441 ctaaaggaac tggtgtgatc accgtatttt taaagttttc gtccgccatt tgatagatca
    43501 tttttccttt atccgttagg ttgtcattat tcactaaatt ctcattggct gtcttgctcg
    43561 ccatgatatc aaaacttttt tcgccgaatt tttcttgtac ttctggagaa gaaagatatt
    43621 tgatgaattc ataagaggcc tcaggatctt ttgctccgta tggtacttcc aagacgaatc
    43681 cgccacccca cgaccaatgg cctgaacctt cttctttttc tgggagctgc atcacgccaa
    43741 aatcaaaatc atccggtgca ttttccatca aactagagta ataattgata ttttgggcac
    43801 gcatggctac taatccggaa ataaatggat cagatacacc agacccaaat tcggcttcta
    43861 atttattgat cgtatttttc ccataataat cttgccagtc ttggatccac tccaaggctt
    43921 ccactttatt tttagtatca atcttgactt tttcatcttt gtcaaaccaa ctagtcccgt
    43981 tatctgcgtt tagcgcccat acatcagccc ctaaattcca taatggataa aaaccgatgc
    44041 gtgtaaattc ttttccttct tttttatcta gtttacgtgc tgtttcttct aattcatccc
    44101 aagttgtcgg tagatcttgt tcactgattc cagcttcttt aaataacttt ttattataaa
    44161 aaatgacttg tgtatctgta ttgaatggga tcgcataagg atcaccttca tattctactg
    44221 tatcccaaag ctgcggataa aaatccttag aagtgtcttt ttctacatat ttggagagat
    44281 tagttgcttg ctgtgcttct gctctttggg caacggaatt tatgtcctgt acaataacat
    44341 cgggtgcatt tccagctgtt attgcagata aagatttagt ccagatgtca ccccatggct
    44401 gatacttata atttacatgg atctcgtttt gtgattgatt gaaatcctca atgatttctt
    44461 cgatagcttc ttttcgtgca ccggatcccc aaaaggacca gaaatcaata ttttttcttc
    44521 catcacttgt tttttcagaa gaatttgctg cacttgaact ggcatcgctt gcattacttg
    44581 atccgcatcc tcctaataaa aacaatgctg aacttgccag caaccctgta aacaataatt
    44641 ttttcatatt ttacctccaa attttaatgt aaccgatgcc ggttttaata taacgatatc
    44701 attttgttct gaaaataaca atttataagg tatgattcta aaaaaattat taatgatacc
    44761 aatactttat ataattcgcg agcgctttct ttgaattttt taatctttcg tagcagaatg
    44821 agaatgtatt aaaaatagat taggaggaat tttgatgttt agacaccaga aagaattgca
    44881 gtttgaagca aaaccagatc gtccgaatcc attaatcgcg aaatatctgc aggagctgat
    44941 cggcggccaa tatggcgaga tgagtgtagc tatgcagtac ctgttccaag gctggagctg
    45001 ccgaggagaa gaaaaatata aagatatgct gatggacatt gcaacagaag aaatcggcca
    45061 cgtggaaatg ttggcgacaa tggttgctcg tttattagag ggtgcgcctg ttgaagatca
    45121 agaagcagcg atgcaaaaag atccaacaat cggtgccatt atctctggaa tgaatccaca
    45181 gcacgcgatc gtagctggct taggacctcg tcctgctgac agcgtgggca atccatggag
    45241 cggtgcctat atcattgcga gtggcaactt gttagcagac tttagagcta atttaaatgc
    45301 cgaatcacaa ggaagacttc aagtagcacg tatttacgaa atgatcgatg atcgtggcgt
    45361 aaaagatatg ctgtctgttc tccttgcaag agatagctat catcaaaatc tatgggaatg
    45421 tgcagtgaaa gaattagaag aaaaagaagg ttcaatctta gtcccaagta ctttcccgcg
    45481 tgacaaagaa cgaaaagaca ttgcttatga cttctataac ttctcagagg gagaccaaag
    45541 tagtgaaggt tcttgggcta gtggcaaagc actggatggc gaaggcgaat atcaatggtt
    45601 gaaagaacct aagatcgaag gcgctgcacc aaaattagaa ccagtaacac caaaaatgta
    45661 tgggacacct ccattcaaga aataaatatc tacccgtaga aacacccgtt ttttgttcca
    45721 cacgctttgt gagcaaaact gactaaagtc attaatcata accacccttc aaaagggtgg
    45781 ttttctctag agctataagc tcaaatcacc ggccagcgcc taaagacgct ggctttcata
    45841 ttttatgttc aagccatatt gcctttgcca gttttgccca cctcttaaaa ggtttatgta
    45901 ctactcctta gcccttaaaa ggatcgtctt actctcgtac actcagctta tctaacgcac
    45961 tatcatgttt ttcttgttct tgaatgtact ttttgatggt cgcttcattt tgtcctactt
    46021 ttgtcacata gtatccttcc acccaaaagt gtcgataccc aaatttatat tttagatttg
    46081 cacaatctct tgatgatctc ctgaatattg gctcgatatt gattataaat tatttttctt
    46141 ctatactttg gtgtgaatac aatgtggtat ttacacatct actttgtacg ggctaaacta
    46201 tttcccttta ttgctccacc cgcatagcaa gtggttttgt atttcaatcg ctcggcgcgc
    46261 tcaattaggt ctaaagacaa taaatctaaa aacccgctgc ttcactgaca gaaacaacgg
    46321 gttttcagaa aaaaatgaaa tgaaaaagat ctcttacggc aatctatttt atttttttga
    46381 ttttttataa atggaaaatg cttcaagaag tccaagaaat aaagccgtat aaaaacaaga
    46441 acctatgaaa tctttattta ttagatattc aacagaaatc ccgataacac tagccaacaa
    46501 tatatttatc agaagtgtaa aataaggatg ctttttatag aatagaacta gtgttgtttt
    46561 catagactct cctttcttca tatttccaat taatcacaaa ttcacggcat tactagaaaa
    46621 attaaagggg cgcagaagtg gaaaaatact cttcgacttt ccctacaaac caggccatct
    46681 tgtgtttaat aactatacca aatctaaggt acctctaaat ctaaattcca tttgtggcgg
    46741 tgacctccaa tttttaactc ttctatctcc catccagtat acataacctt gatacttcga
    46801 ccacttatat atcgaacaca caaataccta tccattgcag gagtactacc taacttagtt
    46861 gctacttgca tctaaataac agctgaaaag ataggactta ctcttagtaa agtatctgaa
    46921 ctattaattt ttaaactatc atttttatcc tcaactacat gcacatctgt tgcaacttca
    46981 ctttctgtct catccagata aatgattaag gaatcgggaa ttgcaatatc ttcagctgac
    47041 gctggaatag ttgagctaaa ttagtcatca tatctttatt ataaaataac caacagcaaa
    47101 aaatacaatg aaaaacaaac ttggaactaa tgtatcatta ataaatgttg aaaaattcag
    47161 caactcatta ctgtatgatt ttagcagccc aaccaacata taccctataa aagctaataa
    47221 gatggttagg aatcctttag aatttttact cattcataga cacttcctta aataactttt
    47281 attatagaag gtattgtaaa taataatatt gacaaaaagt gactcaaaat aaaaaaaacc
    47341 ttacattata ctggaatgaa ctgtattgat agtgtaccta aaagctctac tgacataaga
    47401 tcgtgtaatc ggtaaagtaa ttttattaat tatacgggat gtaatcaatt agagaataaa
    47461 ctaatcataa aaggtacttt tacattcata attgtcgctt tgagattcta ctttggttca
    47521 ctatctgacc caattgcaca ttttcgatca ttacaagtat tggtgtcgtt agaacaacta
    47581 aataaaaact agcggtagat ttttcagaat ctatgctaat ttctgtatgg atgttccagt
    47641 gatggcaaat ttctcttttc attgtttttc ttgtcgcatg atatgccttt ttgtgttatt
    47701 cagttaaact atagaaattc tttcctagac agatcttgat cccaaatttt acgtttttga
    47761 gcatcgatat agtttaaaat gacattactc atatctaaag agtttagatt ttttaggact
    47821 aaaactgtca gttgttcttt ttcttctttc tgttaaagta ttgtcgcgac ttttcgtata
    47881 cgttaagata tgtcgtgaaa aaacaagttt tgtgacacaa aaaaacgaat gacttgagga
    47941 aatcacctca atcattcgtt taaaatgcta tatattcttt agtttaagat acggaaatta
    48001 atgccatcga ccacactagt agaatgaacg acatttactt ggcctttttt taatttcgtt
    48061 atgtttagca tataaaaata ttatagagtt tacttacaat gcttaaaaca tatactgtat
    48121 aatctgatca attttagcca tgtcttgcaa tggtaagttt tctatttttt tgagttttcg
    48181 ttccttaaaa tcaagagatt ttaattgtgt aataattact tgtcctttta tatctagctc
    48241 ttcaggtaat gagtaacgtg tcggtaaatt ctttatagtg gaagtaattg gacatatgac
    48301 cgaaaacatt gttttacggt taaattcata acgagagacg actagtcctg gtcgtctttt
    48361 ttgaatttct tttcctacgg agggatcaaa atcaatccat acaatatcac cttttttagg
    48421 aatataaatt ctttcttctg acactataaa atttctctcc cttcaggagt taaatcttcc
    48481 cattcgtctt tctcataata ctcggcctct tccccaccac taaatggatc ttcaattttt
    48541 ggaactaacg taattgttcc atcatcagaa tacacaacga tatattcttg gttttctgaa
    48601 ggtttctttc cgttatcaga aggtaaagtt accactacag aacttccttg taatctagat
    48661 tttgtaacaa gcattatcat cactccctta ataaaagtat actatataac actaagtaac
    48721 gcaaaattcc cctttgtaaa ctatctagaa aattgttttg tttaaagtat atcttattgg
    48781 atataaatag aaataaattg tagccagttc attttttctt taactaaaaa aataatccaa
    48841 gaaacattga acctatggat ccaaaagcta cccaaatact atagctaacc ccccgctacc
    48901 ttcaattttg cagataaaac gctttgggag aaaatttcaa agacaacagg ccatcctatc
    48961 atgcccgatt ataaacaaaa agctggctat tccttttgct ctgacaaatt tcaattggga
    49021 aagttcacga aactagcagg tgaagaagtt tcaactgttc ggatcaaaga atgcccgctt
    49081 caaatagaaa cattggttca acgaatttca actagacaag actttgctat tgtagaacgt
    49141 gagatcgtag ctatttttgt agaagaaggg attttacatg atccaactca tatcaatgtg
    49201 gataaatggc aacctcttat ctataaattc agagaatata caactgccaa ccagtcgtta
    49261 actttgaatt ttagattcca agaattcaaa gagtcataat gataaacatc gttaggtata
    49321 aataaaaaag actcgcagca cgagtaaaaa acaaatagaa gctatacatt agaaaggtcg
    49381 actgtgaccc tatagatgca gtatatgcag cttatgagca tttcttctgt tctctttgtt
    49441 tttgggatct gtgctgaagt ctttttcgtt ttttgccgct ctttctttga aaaatcgatt
    49501 atgttatacc ttctccatta ctaattcagg catctgctga gtaatgattt ttcgcgcaaa
    49561 agaaatatct gttacccaag gttcgatttg ttcttcagtc aagacaagcg gcattcggtc
    49621 atggattggt gcgactgtgc ggttaggttc agtagtcatt atgattgatt ctgccatttt
    49681 ttcatcctga tggctacgat aaaaaccgcc aatatacact attttttcct tatttgaaaa
    49741 cataaatttg tctttttctt cattccactc attgggaaaa cacaacgatt ttgcaaaaat
    49801 ggttgatgaa aggtcttttt ttcttctact gtctctgcac gggcattaat catcaattgt
    49861 ccttttttaa atccggtaaa tccccacttc atgatttccg gagtgaggat gttttcttcc
    49921 tcttttctta acgtcacaac aagatttgac ggaaaaactt ctccagctgc taattctgct
    49981 gcctgcttcg gttgtttcgt ctgggcttct cgataataat tctgaaggag ctctgactct
    50041 agatcaaaaa aataacgacc acacatccta atccctccca atcttttttt ctatcataca
    50101 ctgcaacaag aagttcgcac caacaaaacg ctttcaattt ttgtagaact aaaaaagttg
    50161 tgacaagtga caaactctcc agtgaatggt attctcctgc caactcctcg gtcacaagtc
    50221 acaatattca acaaacatga gaagctgctt tttgaaattg ttccttgtga ctcggagtga
    50281 aacggcaggc ttacgacctc tgggtaaacg gtgttcaaaa gccagtttct cggtattaag
    50341 ccaaatttat gcaaaaatgt agaaagctat tttcacaaaa tttttcttaa tactcgaaac
    50401 taagcgactt tttcacaacc tcttccttaa acggtgttca aaagcttgca tctgcggtaa
    50461 taagcccaac caaacgaaaa atatgagcag ctatttttat ttggctgttc ttattacttg
    50521 atgcagggca gctttttcac aacctctcca ctaaacggtg ttcaatcagc taaccttcgg
    50581 tattagctca aaaaacggca aaatatgagg aactattttg ccgtttgttt ctctaatact
    50641 caggtcaaag cgctgatttc acaacctcta atacacggtg ttccagaagt agcttcttcg
    50701 aaaaataagc cgaaatttca caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt
    50761 tcttgaagct gaccacttct gtcacaacct ctaattatta aagaaccttt tgcgaagtta
    50821 acaatctttc tttgatcaat tgaaaattct gcctaagtag tgatagatcc tgtgtgactt
    50881 tcaacaataa gatacttccc tggatttcag caatcaacgc tttggcttga cggtctgctt
    50941 cttcatcgga cagtttttct tcagaaagtg ccaggatatt ttgtttcgta tacttgaccc
    51001 attgattgac taattctagt agcaacagac ggtattcttc atccactgta ctcaactcaa
    51061 taatcaaatt acctacagga cagccatgat aagtgatctg tgtctcatga tcagcgaaaa
    51121 tccagtccaa catttcttct aatgcttctt ctggctgttt tccagcattt aagatgtctt
    51181 cgaacaattc tgtctgccat acgtccatat gcgcatggat caccgctaga caaacttctt
    51241 tttttgaaga aaagtaataa taaaattgac cttttcctgt atcagaagct gctagaatat
    51301 ctcggattga cgtttcatga tagccttttt tataaataag atctttggtc gcttccaaga
    51361 tcttttcctt tgttttcaat gatattctcc tttttcattt ctcatagtcc tatattatac
    51421 agtaaattca tcattttttc ttcttaatcg tttaaaaaag actgtgccaa attatctgac
    51481 acagccctca ctataaaact gttctcatat agctagatgt tcattgattc aagaactgcg
    51541 aggacaaaag caattcctat cttatgatag ttgctctaat acttcctctg ttgtcatcac
    51601 ttgatctgca ataaagccaa agttcgtcaa cgctgcatcc attgcttctt ggccaggagc
    51661 accaattgca tctgtcgcta ccacaacatt gaatccactc tctaccaatt cacgcatatg
    51721 ggaatcgcta cacaagtttc cgttcattcc accaagaatt actgtgtcga ttccattttt
    51781 tctcaattgg agcgccaaat cattgctttc tggtccaaag attttatgag gagagctgat
    51841 gatcgtattt tcatccaaat aaggtttcaa ttcttcgata aaatcggctc ctgaaccttc
    51901 ttccactgat tcatattgac tttttctagc aaacatctgc tgctcaagca tcatatgttc
    51961 tcctgcaccg ccaaattgcc atttatggtc atgtgggtaa aaataatgag gagaaataaa
    52021 gagtttgtat cctttttctt ttgcttgttt taccatttca atcatatttt cgatcgtatt
    52081 gtatttttct aagatatctt ttgtcaaacc aaagccaccg cctgctggtt tcaagaactc
    52141 gacttgcggg tcagtgagaa ctactgctgt atttttatta ttgaacatgg tggattctcc
    52201 attcgttatt tattttaata catcatttag agcttcactc attgtcggat gagaatagat
    52261 ttgatctctc aataacgtat aaggaagttt tccattcata gctagcgaaa tcaagttgat
    52321 gacttcatga gaatcttccg catagatact tgcccctaga atcaagtcag tttcagggtc
    52381 gactaaaact ttgaatacac ctttaggatc ttctaatact tgtgctttag ggacaccgct
    52441 tgtcatatac ttgaataatt tgtaattgac gccttgtgct ttggcttgtt tttctgttaa
    52501 acctacattg gataaagtcg gagtgataaa tacactgtaa ggcacagctt tccggttatt
    52561 cgttgttcgt ttattctcgc ccttcaactg atccataatg attcgataat catctagaga
    52621 gatataagtg aactgcaatc cgcctttgac gtctccaatc gcccaaatgt tgtctgcatc
    52681 tgtacgaagg tattcatcca cagcgattgc tccgcgatct gttagtttaa catctgtatt
    52741 ttctaatcca agtgatgctg tacttggttt tcttccagtt gcagccaaaa cttttgacgc
    52801 ttggattgtt acttcttggc catcttctgt aaaggtgacg gcagctgttg attcttggtc
    52861 tgctacttga tctacagata cacctagatg gaattcgatt cccgcatttg tcatgtcttc
    52921 taaaatcatt tgcgcgatat cttcatcttc acgtggaaga aattcagaat gggcatcaag
    52981 aacgacaact ttagatccgt attcattgaa cattgatgca aattccaagc caatatatcc
    53041 agccccgatg atcactaatt tttccggtaa ttgttcctga tccatcgctt gcgtagaatc
    53101 aatcaagtag cgacttgtat tcaatccttt gattggtaaa atgattggtt cagaaccagt
    53161 attgatgaaa atccgttcgc cttcaacaat cactttttca ccattattcg tcacttcgat
    53221 ttgatggtta gaaagaaaac gtgctgtacc gtccatcact gtcccagttg cctcatcgct
    53281 gatcatatga taatttttgg cgcgaagcat gcccgtcaat ttttctttcc gagcaacagc
    53341 ctctgtaaag tcgattcctc tttctccatt gaaaatcaat gatttagaag gaatacagcc
    53401 gatgttgata catgttccgc catacatacg tgttgacttt tcaacgacta aaaccgattc
    53461 accttttgaa gctaacgcct tcgctaaagt cttaccgccc tttccaaaac cgatcacaat
    53521 attttgatat ttttccatca tttttccctc gcttcttttt tacctaccga ttggtacaaa
    53581 aatatgataa ccgataattg tctattctcc aaatcatctg ctttatttgt caaaaaaaac
    53641 cagacaaaaa gcggtccttt cacgttttta gtctggttcg atttccttta ttcttctaaa
    53701 caatcgttac ttctacatcg atatttcctc tagttgcttt ggagtaaggg cagaattcat
    53761 gcgcatcttc tgcaattttt tgggcttctt cttcgctgat gccatcgata tgcacttcta
    53821 atactacacc gatctgatag ccgccatcat ctaaattata aagagagaca cgtgctttta
    53881 ctgtggactc tgctgtcatt cctgcttctt tgatcatatg ttgtaccgcc ccattgaaac
    53941 aagaagcata acctgctgca aataattgtt ctggatttgt tccttctgca tggattcctg
    54001 gaggagtgat tttcatatgc atcgagccat ttggtgcctc gacttctcca ttgcgcccgc
    54061 catggttgat cattgctgtt tcgtatgctt ttttcattgt actgctcctt tcgattgacc
    54121 atttgctact tggctataat tatagtgtat gacaagtaag gcgctttcta caaaaattct
    54181 gcttattcga ataccagaat gccgtcttct actatttttc caaaaaacaa aaaaatacta
    54241 ctcgtgaaca acagcgtcat atttgttcca aaataaatag caatcttttc tacataatct
    54301 tttatatgat tgattttaag atacatatat accagaaagt tgaccccata aaccaatact
    54361 gttaaaaaaa taaccatatt cgttaccatt ttttcctcct tttgctggtc tccctaccag
    54421 cactcgattt aaccatacca ctttttttgc cgtccaagca actagccttt caaaaagact
    54481 ggtttattct gctgttaatg attcaagatc agaaaaatgt ccgaataatt ttgctaattt
    54541 tactaacgcc aacttgttct ttccgaattc atcattttct atctgtaata ctagtaacgg
    54601 ctcatgtaag cttaaacgga tcaaaaacca gccgtttccg tatggctctt ctagatcata
    54661 tcgaatacct tcttcatttt ccgggtcgaa gttcatccct ttttcttctt ccaacagtcg
    54721 cttcatttct tctaatatct tgtttccttg ttcgcgtggt tcatcgctga acaattttaa
    54781 tcggatttct tgtacttcta cgggctgttt caactctttg atttgttcat ctaatgtgat
    54841 accttttctt tttaattctg gcaaaagcat caggatcttt gcgatgacat atgcaccatc
    54901 atccagaaaa tagttttcct tgaatgcagc gtgtccgctt gtttcgatgg ctagctgtgt
    54961 atctttccca agacggttaa gttctaatgc tttattgatt acatttcgat agccggaaat
    55021 ataacgaact tggatgcctc ctttttcttc aatgaatctt tgtagatgag aagaagtagg
    55081 ggaattcgtc acgattcttg ttcctggatg ctcttttaat acgattgtac ttaatactgc
    55141 gatcaaatta tttcgattga tcactgttcc agaagcactg acaactgcag aacgatccac
    55201 atctgtatcg aaaatgatcc caagatctgc ttcatttgct aaaacagcct gcttgatact
    55261 ttccatcgct tctttattat caggatttgg gatatgatta ggaaatcggc catctggttc
    55321 caaaaattgg gaacctgttg aatccgcacc taagctattc aatacttttt cagcaaagaa
    55381 tccaccagca ccatttccgg catcaacaat gattttccaa ccatttagtg gtttgctttc
    55441 tagtgttcca atcccctttt taatttttgt gactaaatct tgcgcataag gtgtcaaaag
    55501 gtctgctttt tctacgcttc cagtttgttc gctttttatt ttttgctgct gtgataggat
    55561 aaaagcaata tcttcttttt ctgctcctcc ttctgaggta aagaatttta ttccattata
    55621 ataataggga agatggctag cagtcagcat aaccgcagca tcgcacgaga actgttcaaa
    55681 ttgagtggac ataaacatag caggcgtagt agctaattcg aaatcgatga catgtatccc
    55741 ttgttctttc agactttgga tcaacgcctc tttcagtgct ggtccgctta tcctactgtc
    55801 atgaccaatc ccaatcgtcc attttttatt tggatcggtt gatttcttct ttttctttat
    55861 ccagtttgct agtccccagc cgatcttttt taccatgtct gtcgtcaagt ttacttcata
    55921 tccttcaact ggtaatgcga ttcctcgaat atccgatcca ttttgcagcg ctttcatatc
    55981 tttcatataa aagtcctcct catttattcc ctcatttttt ccagcttttc tgcaaatcgc
    56041 tgtgcttctt cttctgagcg gcaaataata atgaatgtat ctacaccggc catcgttccg
    56101 acaacttcag ggtaagccac ttcatctagc caattcgtta ccacatcggc accatttcgt
    56161 tcagtcaata cgataaccat gaactgaaca gactggatac gcaaaacctc gcgtctaatt
    56221 gctgtacgca aacgttcttc atttaaagaa acagatggct ggttaaataa tgtatagcgt
    56281 actattttgt tttcattttg actttttact aacttcattt ctcgaatgtc tcgagaaatc
    56341 gttgcttgag tcacatcggc gcctgcttca tgcagccgcg caagcagctc ttcctgtgtc
    56401 ccaataggtt gttctgtaat gatctggcgg atcagtgctt gtcgctgttt ctttttcata
    56461 ttagacacct ctcaatgttg attatagcaa aagataagta atatttcttc atattttggt
    56521 attttttact tttatttttt gttttcattc aggttgctaa cctttttcta ttttaacacg
    56581 caaaatcgtc ttcatttttt caggtgctga ttttcttgga tcgctgatgt aaatctcttt
    56641 gtgttcttta gaagctcttt catagccttc ttttgcgatg aatgcttcta atttctcaaa
    56701 cgttgctggt tcttcggcat agggcccgac gtgtaagatt tgggcacaaa gaccttcttc
    56761 catctttttg aatactactt gttctttcaa gtcttccgga agtttgctag aacgctgaat
    56821 ggcttcttgt gctatcgctt ctgtaacaaa gtcaggctgt cggatcatca attgataaga
    56881 aaaatgttct tttttcatca ctggttcatg caaatacttt tcttgcagtc cccattgtcc
    56941 ttccagtgga tagacagtat acatctgata atcaggaatc agccaatttt ttttaggcga
    57001 catgcgtatt gcatagctga ctgcatatag acaggctact cttcgtttaa agtcttcctg
    57061 attcgggtcg ccgatccctc tgatgctaaa gaatgatttt ttaggaacct ctagtatttg
    57121 cgggcttttt ttcatactat agctcttgtc tttacgccat tcaatttttt ccatttttct
    57181 tcctccgcga aattccattt agttatttat tatcatacct ctttttgagt gacttggcta
    57241 atcgtgttga cactattttt cagtttgtgc tagaataagt gaagtaaata aatcgtacag
    57301 ataacacgtt tcggcgtgtc gagagagagg cggtttctat ttttataata gaaatcactc
    57361 tcttttttta cgaaattttt tagaggtgat gtaaatgaca aaacaaaaac agctgctttt
    57421 agtacctgca gtaattgcaa cagggatgat gtcttttgcg ggcgtattga tcgagacggc
    57481 catgaatgta actttcccaa ctcttatcag acagtttgat ttaacgactg cacaagtcca
    57541 atgggtaaca acgatttatc ttttgatgat ttcgatcatt gttccgctgt ctacttattt
    57601 gaatcgcaat tttagtctca aaaaactctt tttagcttca aatctgcttt tcttggcagg
    57661 tataatgatc gatttcttct ctcctacctt catggtccta ttgtttggtc gattgctcca
    57721 aggtgcagcg acaggtatcg ctcttccgtt gatgttccat attatcttga catttgcccc
    57781 cctcaatcga cgaggcgcga tgatgggtgt cggtactttg acaacggcca ttgctccagc
    57841 aattggcccc acttatggag gcattatgac ttcacatttt acatggaatc atatcttcct
    57901 gtttcttgtg cccgttttgt ttctttcttt gattatcggc tggtttgcta ttcccgagat
    57961 ggcagtacaa aaaagtggtt atttggattg gataagcgtt ttaggaattt gtcttttgtt
    58021 tagtggaagt ctaacatttt tgagtacgtt gggaacagtt tccagctgga ttgctttaat
    58081 catcggcggt attggctggt tcctttttta ctatcgaagt aaaaaagtgg agcatccact
    58141 gatccgactg tctattcttt caaataaaac attccgcttg tttttgattg gcttcttagt
    58201 ttatcagttt ttattacttg gtgtatcttt tgtcttgccg aatttccttc agatcgttca
    58261 aggaagtagt ccttttgtcg ctggattagc gatgcttccc ggcgcagcgg ttggtgcttt
    58321 gctttctcct ttttccggga aaatgctgga tcaatatggt ccgaagaagc caatttttgc
    58381 tgggctgatt ctttctttga ttggttggct agcattattc ctactcatag gacacgcttc
    58441 agtgggtgta ttgattgctt gtcatgtgtt ttatatgatc ggtatcggat tatcttacag
    58501 caatatgatg accaccggaa tgaatgcact gaatgaagaa ctacaaggag acgggaacgc
    58561 aatgttcaat accttgcagc agttttctgg cgctgtggct acttcattag tagcggtcat
    58621 tatcaattac gtccagcatc atacttccca taactatgaa gtgtctacta cattaggatc
    58681 aaaagcagca ttaggcgtct tgttgctgtt gcttctcgta agctttgctc gattcgccta
    58741 ttatctgttc tttgctaaaa aagcgtagat tccatatacg gcaggtgttg catctgccgt
    58801 ttttttgtgt gaaaatggtt gtttgtaaaa ggaggctttt ttatggaaaa aattgccatt
    58861 atcggtggcg ggatcattgg tatgacccta gccagttact tagatacatc aaaattcaat
    58921 gttgctttat ttgatgaagg gacaggacag gcaactaaag ctagcgctgg gattatctcc
    58981 ccttggttgt cgaaacgcag aaacaaacaa tggtatcgtc tggctaaaga cggcgctgct
    59041 tttttcccta aacttataaa agatttccaa cttgatcaaa cgatttacgc acaatcaggg
    59101 acacttttgc ttcgacctga aaaagattta gctgaattgg ctgttcttgc cgagaaacga
    59161 aaagaagaag cgccagaaat tggaaacatc gaatggcttt cacctgaaca gacatctcaa
    59221 gcacttccgt tattgaaacc agcagtttca ctgcgtatca gtggtggtgg tcgtctggat
    59281 ggaaaagcat atttagaaca tcttggtcag cgtttagcac aaaaacaaat ggagcagatc
    59341 caggcaaaag tcactttgca taagaagagc gattcttggc tcatcaaggg accgtttgga
    59401 gaatacacag ctgatcgtgt aattttgaca cctggcccgg cacttaagcc tttattacaa
    59461 gaattaggct atgctgcaga tatacgtccg caaaaagggc agctcttagc atttcagaca
    59521 tcttataaga tgagtcaaga ctggcctgtt gctatgcttg acggagaagc tgatttcatt
    59581 cctttcatgg atggaaagat ccttttaggt gctacccatg aaaacgatca aggctgggat
    59641 ttggctccta ctagcgaagc ttataaggga ttgactaaga gtacagaaca gttcttgact
    59701 gatccagatc agataaaaaa ctggccatac gagttccgtg taggtacccg tgcttatacg
    59761 tcagattttt ccccattttt cggcgtactg ccagatgatc caagcttact ggctgctagc
    59821 ggtctaggct cttctggctt gaccacaggt ccttatatcg gctatctatt agccaacttc
    59881 ttaaatactg gtcattggcc tacggaagat tatcaaaagg acatctccac ctatattacg
    59941 aaaaatccat catagaaaaa cagctttttc aagtaaggat cccgagcgat attgcgcatg
    60001 gattacttct tgaaaaagct gttattttag ttcaatttct gaatcaaatt ctccaaactt
    60061 tcttttgctt catctggcaa gagatctttt cctatctgag cttcaatgaa tcgtaaacga
    60121 atatcaagtc gttgtttcac cagattttta taggacgtat cctcaaaaga aacaggaaaa
    60181 tctggtatag gtaaatagtg gatgtcttca aatggaccaa acgacttgaa ttctgccgtt
    60241 tgttgcacga ttctttcaac gattgacaat gtcgtttcag gtttgatttt tttatcatcg
    60301 aaatatccag tattcaggac atagcaggct gtttgctgtt tcaaaaacaa ctctcgaaaa
    60361 gcttgatagt cttccctaag aggatagaca cggaaaggat tagcaaatgg ttcaatgact
    60421 agctcatcta gctgtctttt tgtagtgata ttttccgcgt ctgatcgttt tgttgctaat
    60481 gttgcaccaa aagacgctgc taaaactggg tcattgatct tgataattgg cggaagcgaa
    60541 tcatctttca tgatccaaaa aacagcatcg atcttttcgc taagatgatc gactcggtcg
    60601 ggtgtcgcat aacgtgattt gactgtccgc ccatttccgt ttcgtatatc tcctgttact
    60661 aggacttttt ctcctttact tgtacatgtc acgcccacat tctgacaagt aaggaaagaa
    60721 gaaatggccg gatcatcaga cggatagtct tgtgttttat caaagtaaga aggttccaag
    60781 gcagtagcaa aaccattttt tcgagaaata acgaaagcat cgtcatgcaa gatcgaaaca
    60841 gagtgacctt ccgtatgttt tgctaaggta atcgttgatt ttccagaacc ggacaaccca
    60901 aatacagcca tcgtataggt ctggtcatta ctagcatatt gtttcatccc accgtggcag
    60961 gcaataaagc cattgcgatt tcccaatgcc caagcaagcg tcaaagtcgc tttttttaat
    61021 tctccaaagt aacgtaatcc tagcacagcc gctgtattat ggagagcatc aaacaaaatg
    61081 agtccatttg gaaatgtttc atgtgtccat tcgggatcac aaaagatata aagatctccc
    61141 tcatcaaagg aaacagactt ttgataagtc tctaagatct tcgaattcgc tggctgaaaa
    61201 ttcagcaaat aagaatacaa attgttctca aatccttctg gaatcagcaa atgactttgc
    61261 acagaaaatt cttcagatag gccaacgatt acttttgtat ggtaaaactg gcgcttgcga
    61321 ctttgataca cagcttctct taaaattttc tcgtatttgc tttgttcctt gtctaagtcc
    61381 tcaaagatcc gccgagcact tgctgttctt cccacaatgc ttccatcatt gaatactagt
    61441 gtcctaacat cagctggtaa atctagttct tcagcatgtg agattgttaa atctgtgatg
    61501 atcgttcctg gactcccttt tgctagttga taagctgtct tcctatcaaa aacttcatga
    61561 acattattac cgtaaaatgt cgtttctaca atcgatcgaa tactggataa cagtggattt
    61621 ccacttgtga tttcgtttaa ttcgagactc tcttttgtac tcatggctcc tcctcattcc
    61681 ctaaacaaaa aaacgttttc tttattatac attattcgag tttttatttg tactgctgcg
    61741 ctgtgggaag caaacgagtt atttttcaca caaaaaaacc gagaacttga ataaacaagt
    61801 ttctcggttt catcattttc cttttatcgg cttagtacca gccgtttgct aaccagaatg
    61861 ttttagcagc atcccatgaa ccataacgag atgttacata ttgttctgct acacgttctt
    61921 gattggcagc tgaatagtcg ccgtttaagt atgaagcatc taattgataa cggccgatgt
    61981 aacgtccgtt agtagctgtg tatgaaccgc ctgattcttt ttgtgcgatc cattcttttg
    62041 cagagcttga agttggcgct gttgcagcag ctggggcagc aggagctact tcaactgttt
    62101 caacaggtgc aacgtatgta tgttcttgcg ttgctgtttc agttgtagat gctgtatttt
    62161 ctgttgtttt gttttctgtt gttgctgaag aatcatttga agttgggatt gttaattgtt
    62221 caccaacata aatgcggttg atgtttgcga tcgaattttt ttcagcaatt gcatcgatca
    62281 ttgagttgtc tcctgcaaat ttttgtgaga tcttagataa tgaatcacct gattttactg
    62341 tataaacttc atcagcgtga gcatttgtag ttcctacaaa cattgcagta gcaccagcag
    62401 caaaagttgt acctaaaaca attttcttaa atgaattcat attaaactcc tttttttctc
    62461 cgttttttat tctttcgacg ctattaactt tatcatttag aaatatttca taggtaaaag
    62521 aaacatgaca tttaatgaca aaataacgaa ttatttaata tttgtaacat ttaaacaaat
    62581 atttttttga tacaaaacca taaaagcctt gttgtataag caaagtaatc gtttttctat
    62641 gtttttttat ttttgaatga aaaacgcaga ttctgtaaca ttcactgcaa taatccataa
    62701 aaaaaagcaa aaaaattttt gatttttatc aaattctctt aaaaaaatgt aaaaaataca
    62761 aaaaaaccag taattgttac aacaattact ggacaaaaac tttgaataat gttaactatt
    62821 tttttatttt aactttctcc gcaataattt ctgggcatgt tccaattcgt ttataacgac
    62881 ttcttctgtt tctttagcta atatttcatc taatacatca agccattttt ccggttcttt
    62941 tgttcctaga cgtccaatag cccaagctgc tgttcctctg atgacagggc ggacatctgt
    63001 taaacattct gaaatctcag gcaatgccgt tcgatcacct agattagcta aagcaatcaa
    63061 tgcgtttctc tgcaaaggtt tcttcccacg ccatgaacca gctaaatgcc caaattgctg
    63121 tttgaagtct ttattagaca tcgaaagcat tggctttaat tttggatata tttcgtctac
    63181 ttttggttcc atctcttcat gaaaatgaaa atcttttcct tgattgtaag ggcagactaa
    63241 ctggcagata tcacatccat aaatgacatt tcgcattttt ttacgatatt cttccggcat
    63301 catccctttt gtctgagttt gataagacaa acatcgctgg gcattcattc ttccgtcacc
    63361 aagcaatgct tttgtcggac aagcagtcac gcagcgcata cagtcaccgc aaccaaattc
    63421 tcctggttta tcaggctcaa atacaatatt agtaacgatc tcaccaagat agacaaatga
    63481 accgaactct tcagtgatca acaatccgtt tcgtccaata aatcctaaac cagctcgctg
    63541 tgctacagcg acatcgatca gttctccagt atctacttgc ggagctagac gccattcctc
    63601 ttctttttgc catttttctg ctcttgtttg gatgaattcg atcaatcggt tcaaacggtc
    63661 tctgagtata tcatggtaat cgatccccca agaagcacga gcaaactgcc cgcgtttttc
    63721 atccctaggc acttcttcat ggatcctagt aggatacgca agtgcaatgg aaatgatcga
    63781 tttcggctga tcaaatgtca tttctggata aagacgctca tcgatatttg gatgttcaaa
    63841 gccagaagta tggccagctg ctttttgttc ttccaacgat tcttttaatg aatcaaaagg
    63901 ttccgccgtg gtgaacccga ttttgtcaat tcctaatcgt ttgctttctt gtatgatttc
    63961 ttcttttaat gtcatggtct tcctcgcttg ctgttaacgg ctgtataacc cataatatag
    64021 tttttctttt ttcagctgga caaactggat ctgctgatcg gcaatcttct tttcttccat
    64081 ccattttttt cttgcagcaa atacttccca ataatttgtt gaaattaatt ttcttttgtt
    64141 atctaatgca ttaaaaaaat tcaatgaaac tggttttgta cttaacagtt catggagcct
    64201 tacctcttcc catggcgaaa actcagacag atcgcgggaa tacaatactt cttcatagag
    64261 atttttttgc tgtgtgtacg tgaatgtttg cgggattttc ccaggcctag caatttctac
    64321 tagacgatta taaaacatat tcattaattt gctgttggca ataaattgac ttttataata
    64381 ggccgactgg atctttttga ttactccttc tgctttgatg actgaaaata atgcaggcca
    64441 tgctttgacg gttatttcgt cgttttgttt aactaatacg ccaggtgtga agccgactgg
    64501 agaaaggaac acaaaataac cgataccggt attttcatct aaaggctgaa attcatcaaa
    64561 caaccatttg cctatgtaca gctcttcatc tggttctgtt gtctcatttt gatttgctat
    64621 gaataattta gctaattctg cttcaagaaa ttgaaggtct tgatccttgt cggtattttc
    64681 ctgctggctg atcaatcgaa agacttcttc tttaatcgta tatttatctt tacgtgtaaa
    64741 attcatagcc acaccttcct tccttactct aactataacg gaatttcttc aaaaaaggta
    64801 tctgtacgac gaaaaacagc ataatttttt ttcatatctc ttataaaaaa tgcaaggtct
    64861 gctcctcaag ctagaccttg cacttttcag ctttcttttg tttgtgacaa accttcatgg
    64921 atcgtttcaa tattccattt catcatctga tagtaagaat ctccttgttc tccttctttt
    64981 gctatggaat cagtgaacag tttatcatag attttcaaac ccgtttcttt tgctacccgt
    65041 tccatgcttc ttgagtctac actggtttcc acgaataaaa ccggtacttc ttttgctctt
    65101 atctgatcaa tgatcgcttt catttgatca ggcgtacctt gactttctgt attgatctcc
    65161 catatataag ctgctggcaa atcatatgct cgtgaaaaat acttgaatgc cccttcactt
    65221 gttactaata attttttgtt ctcttcgata gaagcaaaac tttccttcgc ttgtgtatct
    65281 aattctttta gtttttccac atatgcttct gcattttttt tatagagtgt cgcattttct
    65341 gcatcttttt cagagaatat acgtgcgatt tcctccacat attttattcc gttagatagg
    65401 tctagccaag catggggatc tgcttttgta tgttcttcac cgctagttaa ataaagaggt
    65461 tctacatttt tgctaactgc aaaataatct tttccttctt cttttttagc cgtttccatc
    65521 aagttatcga accagctgtt acctgtttca agattcaaac cgttgtataa aataacatct
    65581 gcatcgcttg cctttttgat gtcttctggt agtacttcat attcatgcgg atctgttccg
    65641 actggtacga tactgtggat atctatttga tctgttccga cctcttttgc catgtccgcc
    65701 aagatcgaat tggtagccac gactgacaac ttttctttac ttccttcatc cgcttggtca
    65761 gaagcctgct ttccgcaacc ggctaatacc aagaaactaa ctgccaagat taaaaagagt
    65821 gatttttttg ttttcatcta tctgcttcct ttctgaaata aaattccttt tgttggagaa
    65881 aataaaaaag caaggataaa aaatgcggta catgctaaca cgatcgtagc tcctgatggc
    65941 caattgtaac tataactgaa aaacacaccg acaactgcac ttagcatacc gattcctgca
    66001 gctgtaatga tcattttcag taaatggttc gttagcaagt aagccgtggc ggctggtgtg
    66061 atcaacatgg caatcaccaa gattgttcct actgtctgta aactgactac agccactaat
    66121 gtcaaaaaga acatcaaaag ataatggatc agcgatgtgt tcagcccata agcttttgcc
    66181 attgtcggat cgaatgatgt gatcttcaat tctttataaa agaaaaagac aaatatcaag
    66241 acgattccac taacgagtgc tgtcagcaac aaatcgcttt ccctaacagc taagacattc
    66301 ccaaataaaa tatgatacaa atctgtcgca ctctgggcat atgaaatcaa gataatccct
    66361 aatgcaaaaa aggagctaaa gacaattcca atcgctgtat catttttcaa tcggctccgc
    66421 tgagtcacga aaccaatcac tgctgctgtt agcatcccaa aagcagtggc tccaaagatg
    66481 taactaaaac caaacatata agaaatggct acacctggaa gaactgcgtg agagatagcg
    66541 tctcccatca aagacatccc tcgtaaaata ataaaagaac cgatgactcc agaagcaagt
    66601 cctacaagca tggaagtgac caaagcgtat tgcaggaatt gataattcat taatccatca
    66661 ataaaggatt ggatcatttt ttctctcctc cttttactaa atgtctgatg atctcaccat
    66721 aggccaattg aaggttcttc gatgtaaaga cttcttgtac tggaccggaa gcgatcagct
    66781 gtttatttaa aagaataacc tcatcgaaat attcttctac tttatgaaga tcatgatgga
    66841 cgatcaaaat cgtttttcct gaattcttca attcctgcaa gatgtcaaag atctttcgtt
    66901 cacttaacgc atcaatccct acgaatggtt catctaaaaa gatccattct gctccttggg
    66961 ctagagctct tgcaataaaa actctctgaa gctgtccacc cgatagttcg ctgatctgtc
    67021 ttttggcata ttcttccatc cctacttttt tcaaagcttg tcttgcacgt tctttttctt
    67081 ttttcccagg tctttgtcca attcgtaaag atggatatgt tcctaaaagt acaacgccta
    67141 atacatcaat tggaaaggaa agatccaatt cacttcgctg ttccacgtag gctatttttt
    67201 tacggactga gtttaccgac tgtccagaaa aggtgacttt accagtagta gctggtatca
    67261 actctagcaa agatttcata aatgttgatt ttcctgcacc gtttggtccg ataataccgg
    67321 taattttttg tggatttatc gtcaagttga tagttttcaa aacagttttc ccttgataag
    67381 cggctgaaag gtcttgaatt acaatggccg tacgttccaa atcttacact cctttttagg
    67441 tttacctaac tttttattta aatatagttt aactaaaatg gaaagcattt tcaagtagaa
    67501 tgatgaaaaa gtttttttcg aattttcctc gcattttatg aaaattttct gtagaatcac
    67561 atcaagagtt caataaggct aacctaataa tgaaaaacat gtgttgaaac gtttgattat
    67621 tttttcttgt tgactcaaca acgaaaggag tttttgtatg gaagaagaaa agttaactcg
    67681 aagtcttagt gcccgtcata tccaaatgat cgcactaggt ggaacgatcg gtgtcggtct
    67741 gtttatgggt gcctcctcaa ccatacgttg gacagggccc tcagtgatgg gagcctatgc
    67801 gattgcagga ttctttttgt atttgattat gcgtgcttta ggcgaaatgc tttacgttga
    67861 tccttcgact ggttcttttg caaattacgc gagcgagtac atccatcctg tggctggcta
    67921 cttgaccgct tggagtaata tttttcaata tattgtcgta ggaataagtg aagtgattgc
    67981 tgtaggatct tatatgaatt attggtggcc tgatttgccg gcaattattc ccggaatcat
    68041 tgtcgtcttg tttcttatgc tggcaaatct tatttctgtc aaggcgtttg gcgaattaga
    68101 attttggttt tcgatcatca aagtcataac gatcattttg atgatcattg caggtcttgg
    68161 ggtaatctta tttggatttg gtaatcatgg tcaggcagta gggatttcaa atctttggaa
    68221 aaatggtgga ttcttcactg gaggcgtcaa aggatttttc tttgcattat cgatcgttgt
    68281 tgcttcctat caaggaatcg aactgatcgg aatgactgct ggtgaagcag agaatcctaa
    68341 aaagacgatc attgaagctg tccagtccac tatcggtcga atcttgattt tttatattgg
    68401 tgctattttt atcattgtga gtatctatcc gtggaatcaa ttgagtgaga ttggttcacc
    68461 ttttgtacaa actttttcta aagtcggcat tacatttgct gcaggactga ttaattttgt
    68521 cgtgattaca gcggcattat caggttgcaa ttcagggatt ttcagcgcaa gtcgtatggt
    68581 ctatacactt gccataaatg gaaagatgtc taaaaaattt ctgaaactat ctcgtcacgg
    68641 tgcgcctttt tatcctgtcg tagcaatctc aggtggaatc ttaattggtc tgatcttaaa
    68701 ttatcttcta ccaatgttca tcaaccagtc agaaaatatt ttcgttttcg tatacagctc
    68761 aagtattttg cctggtatgg ttccttgggt agtgattttg atcagcgaga ttcgcttcaa
    68821 aaagaagcac gcagataaaa tgcatgatca tccttttaaa atgccactat ctccttatac
    68881 gaattatgtg acacttgctt ttttagctat cgtattgatt ttcatgttta tcaatcctga
    68941 aacgagaatc tcattgatta ttggactcgt tttcttgctt tacatgacga tccattactt
    69001 tgtacgcgaa aaaagaaccg gaaaataaaa aaagaacgaa gcttcacctt agtggaagct
    69061 tcgttctttt ttattgcttt tatcaattca attttagcgt ctcaccggga gtcaggaaat
    69121 aattctccat gctcatccca ttcagcgaca agatcgtttc tactggtacg ccagttcgtt
    69181 cggctatttg atttggacct tctccttcca aaactacggt tgtcgcagcc tgtgaagtcg
    69241 cgctgttggt attagtttca gaggaatctg ttgtgtcttg tgttgttcga gcttgcattt
    69301 cagaagcttc taccgactct gctgtctcag aatcagaaga tgttgtgtct tgtgtgcttg
    69361 ttgactctgc ttgaagagag gcgctagtct gcaaataaat atcggaaatc ttagcgacat
    69421 gattcgtata attagccgat aattgattga tcaaagtatc taagtctaca ccgtctttat
    69481 tttctgctgc ctgatacgct gcacgtaatt ttctgatccc ttcgtcggag attgcttgaa
    69541 gctcacgtgc tttttggtta gcaactgctg ataaaccagc tattccctct tgatttccct
    69601 gaatttctgt ctggtattct tcaatcaatg caggcgtctt ttcttcgatc tttttcgaat
    69661 aatcatttac gattgcttga agttgctctg gcaaaccatt tgctgttttt tcttcagaag
    69721 tttgtgtctc ttttgtttta gttgatgact cacttgtttg tttcgtctct gttttctttg
    69781 tcgttgtttc cgttatggtc gtacttttcg cttctgacga attttttcca tgaaaatata
    69841 gacccgcaac tcctcctgct atgatcaaaa acacggcaac tgctgcccca atcatgatca
    69901 tccgcttacg agctgcctgt ttttgctgtc ttcttcgggt catccgaaca ttttctcccc
    69961 actcattttc atcatacatt tttttcacca ccaattttta tgtataatag cgttatcaaa
    70021 cgcttcatat tcttattgta gcaaataatt gtcgctgtgc acatttttat ctttgttatt
    70081 tataagaaaa tttcaccagt tgagatgatt ccaagattgt ccgtcgattt ctccttgcag
    70141 ctgcattgtt cgttcgtcta tctcagccat cagtttcttt atttcatata agagcgcacg
    70201 gtcttgatat tctgattttt cgcttaattc atctaattgt tggatcagcc aatcatttgt
    70261 cataatgaag ttcctttcat ttcttgcagt gtaaaggtca agtcttcgat ctgctctttt
    70321 gcctcagtca gtgcttctac gatatatgct tgtttttcag attcttcttc ctgcattttc
    70381 tgattttcct gtactctttg aataaaccag tcaatccgct gagtcagcga tggtttgcct
    70441 tccaatgaga gatactgctg ataagcaatt agcttctccc aacgtttttc ctgggataaa
    70501 tacataaatt gtgctaaaac gaatggcgga agataggtca tatggaattt atttgcgatt
    70561 cgctgatacg gcctcaaaaa ttcggaaatc gtatattctt cttttcctcc agcttggtat
    70621 tctttttccg ccacacctgt tgtcaatacg attcctagtt ctttcccttt taatacatgt
    70681 gctgctcgtt ccaagacatt atcttgccaa atttttaaat gagcaggaga actataccag
    70741 taaaacggaa actggaaaat gatccgatca tgctgggcca agagctgtag ttcagtctct
    70801 atatctattt ttccgtctgg ataacttgat tccaaatgat gccaagtagc tggtaaacca
    70861 gcagaagctt ctttgaaaaa ttgctgattt aaagattctt cgatcgttgg atggctaatg
    70921 atgataagtg tacgcatccc ttttcctcct ttttagtctt cgctttacag tgtagcataa
    70981 ccgccacaag tttcttttgc cgatgcttgt cattttaacc agactaatca ggttgtccaa
    71041 gaaactgcgg tttgtttttc caactgtttt ttcaaggtat ccaaagcaat attcttaaaa
    71101 ttttcgtttt tcatacgttt acgatagttc gtagccgttt ctccggtact ctttttgaac
    71161 attcggctaa atacgactag actattgaac cctacttgat aggcaatact ttccacggat
    71221 tcatccgtca gagaaagaag aaacgcccct cgattgatcc gtaccccgat caaatattcc
    71281 ttgatactgg tacccatatg atttttgaat actcgcgaca aatggctccg attgaccgct
    71341 aaatgctggg cgatttcctc aacagacaat ttttcagcat aatgtgcctc gatgtatttg
    71401 actgtttcaa cagctaaaga ggaatgaacc ttttgtacac caccgctgac ctttccgcca
    71461 tcttttaaaa ggactgataa aaaacggtag gttaatgctg ttaactgtaa ttcattttcc
    71521 aaggtttctt ccgtatcttt catgcattct aaaataatgt cgatatattt ttgtatgtca
    71581 gaagagacca tcgtgtattg gtcttctctg aaaagcgact gccgaatgat ttcttctgca
    71641 gcactcccac caaatgaaag ccagcaatac atccacggat cttctccatc tgataagtaa
    71701 aacgtcgagt ctcctggacg aatcaagaac agatcacctt ttttcaattg gaattgttga
    71761 tttttcacat gataagatcc tttgccttcc atcacgacat gcaggatgta atcattgcga
    71821 atagcaggac caaaagaatg aaacggcatc gttttagaga aaccacaaaa atcaaaatac
    71881 aattcttttt ctacttgttg atgttccttt tttaaaaaaa tcgattgctc cacgtctatc
    71941 cctccttact cctttagtat aatgcaacaa aaagttaaat aaaagtcaca gaaatatatt
    72001 aaaaaggaag cgatttcttg ttaagtttaa gtcattaaaa gatctttgtt attcgttgta
    72061 accggtttac ttagtattat atattgaaca ggagaggaat acagattatg aaaagcaaaa
    72121 tgatccaacg tgtgtcctac gctttaggcg cttttggaca cgacacattc tatgttacat
    72181 taagcactta ttttatggta ttcgtgacaa gccagatgtt cgcaggaaca gataaggcaa
    72241 cgaatgcaaa aatgattgct acagttacaa gcttagttgt aggtatccgc ttagttgaaa
    72301 ttatttttga tcctttgatt ggtggcatca tcgataatac tcgtacaaaa tacggtaaat
    72361 tcaaaccatg gttagttatc ggcggcgttg ttagttccgt actcttggta gcaatcttta
    72421 ccaatttctt tggcttagct actcataata cgactttatt tatcatatta tttgcaatcg
    72481 ttttcatctt attggatagt ttttattcat ttaaggatat cgctttttgg tcaatgattc
    72541 cagctttgag tacggaaaca aaggaacgtg aaaaatttgc tacgtttgct cgtttcggct
    72601 cttctctagg tgcaaatggt actactctag tcgttgtccc tatcgttact ttctttacct
    72661 atcttgttac tcataaacat attgaaggcg cttcaggctg gttctggttc ggtgtgattg
    72721 ctgctgttat ttcaggcggt actgcgatta tcactgcctt gggcacaaaa gaagtcgata
    72781 ctgcgatccg tcagcaaaat gaaaaagctg ggatcaaaga tgtgttcaaa gcagttgctc
    72841 aaaatgatca gttgatgtgg cttgcccttg cttatatcgc ttatgcgatt gccaatgcag
    72901 caacaactgc cgtattattc tacttcttca aatatgtact tggccaacca actgaatttt
    72961 ggatcgttgg tctagttgct gccttacttg gtttagtagc tgttccacta ttcccaatgc
    73021 ttacacgcgt catctctcgt cgctacgttt accttggagg gatcgcaatg atgatttctt
    73081 cttacttttt ctttacgatc gcaggttcaa gtttgccaat cgttatcatc gggctagtat
    73141 tgttctactt ccctcaacaa ttgattttct tatccgcttt gatgacgatc acagactctg
    73201 ttgaatatgg tcaatggaaa aatggtatcc gtaacgaagc tgttactcta tcaattcgcc
    73261 ctttactaga taaaatcgct ggtgctttgt ctaacgggat cgtagggttt gtcgctatcg
    73321 cttctgggat gactggtaat gctactgctg ctgatatcac tgctcatggc gtaacgactt
    73381 tcaaagctta tgcattctat gctcctgctg ctttgatgat tttctccgct attatttttg
    73441 cttggaagat tacattgaca gagaaaaaac atgcacaaat cgttgagaaa ttggaaaaca
    73501 aattggctcc agctgataca atggaagatt aacttcacga tgcagtagtt ccttcccatt
    73561 aagaaaggat cttgaaaatg aagattacag aaaaagattt tggccaaggt tatcacttga
    73621 taaccttgga gaacaaaaac aagctagcac tttctatctc tgatttaggt gctagaatcg
    73681 tcagtttaaa atcaaatgat cgagaattag ttttgggatt tgacaccgct gaagaatata
    73741 tcgaaaaaga tccgtatatc ggtgcttcta tcggtcgcac cgcagggaga atcgaaaatg
    73801 gccgcttttc tctcaatgga aaaacttacc aattagccac agatccaaaa actggacata
    73861 atctgcatgg tggtgctcct ggatttgaat taaaaaaatg gtcttatgtc attttgaatg
    73921 gcgaaaatga agcttctgtc atttttacta ctacaagtcc cgacggagaa catggttttc
    73981 caggtacaat ggatgtggaa atccgctata ctttgacaaa agataatatc tggcgagtga
    74041 cctctcgcgg caccagtgac caagatactt tattcaatcc gacaaatcat gtttacttca
    74101 acttgacggg agatgcttct cagtcaatcg atcaacatga gctttggctc aatagcgaag
    74161 cttatgctcc tttgcgaaca gatagtattc ctataggggt aaaagaaaat gctgcaggaa
    74221 gtgctttcga ttttcaaata cctaaaaaat tagcgtccgt ttttgctagt gatttggatc
    74281 aaaaaaatct tgttgacgga atcgatcatc catttttctt aaaagaaacc ggcttgggta
    74341 aagaagccgc tcgcttgact agccccgata aaagaatcca agtagatatt gctacagatg
    74401 cttctagtgt ggttattttc actgcaaatt tcggcacaga aacaccagaa atgcgcaacc
    74461 gaaaactggc acatcacggt ggcatcacat ttgagactca aacagctcca ggtgcagagc
    74521 gcttctcagc atttggttcg attcatttaa aagccggatc agtatttgaa acagtaacag
    74581 aattcaaaat caaaacaaga aaggaataac tcatcatgga aatcaaaaga agcttaaaca
    74641 caaaatttgc cgaaacattc ggacctaaaa aaactacaca atacttctca ccaggacgca
    74701 tcaatttgat tggtgaacac acagattaca atggaggcca tgtcttcccc gcttccatca
    74761 cttatggaac gcaaggtgta gcagcacctc gagacgataa taaaatatta gtttattcca
    74821 caaactttga cgatatcggt gtcattagtt ttactttaga tgagctagaa tatgataaaa
    74881 aagcaaactg ggcaaattac gtaaaaggaa tggtccttaa attaaaagaa gctggacact
    74941 caatcgatca tgggtttgag ttattagtgg aaggaacaat ccctaatggt gcaggacttt
    75001 ccagtagcgc ttcattagaa ttattagtag gtgttgtatt agaagatctg tttgatttaa
    75061 aaacagatcg cttggaacta gtccaaacag gtaaaaaagt agaaaatgaa ttcatcggtg
    75121 tcaattcagg tatcatggat cagtttgcca tcggcttcgg tgagctagat catgcaatct
    75181 tattagatac aaatacgctg aaatacgaaa tggttccagt gaaactagat ggttatgcaa
    75241 tcgtcatcat gaatacgaat aagcggcggg aattggcaga ttcaaaatac aatgaacgcc
    75301 gtagcgaatg cgaagaagcc ttggcacgtt tgcaaaaaac tttgcctatc tcttctttag
    75361 gagacttaga tgaagaagaa tttgaatcaa ctattgacca aatcggcgat gatacattga
    75421 tacgcagagc tcgccatgcc gtttctgaaa atcagcggac tttgaaggca aaagctgaat
    75481 tagaagctgg gaacttagaa gcatttggtc aactgttaaa tgattctcac cactctcttc
    75541 gctatgatta tgaagtaact gggatcgaat tagatacact agtagatgct gctcaaaaac
    75601 aagaaggtgt cttaggtgca cgaatgacag gagctggatt tggtggctgt gcgattgctc
    75661 ttgtcaaaga agaaaatata cctgccttca aaaacaatgt ctatgatgaa tacatgaaag
    75721 ttgtcggcta tgctccggaa ttttatgttg cacacattgg aaatgggaca acaaagatcg
    75781 atccagaagc tgttcatgtt tgataaaaaa atcaacgatc tcagctaaaa acaaatagat
    75841 aaaaataacc tctcagcaat ttccaaatgt gagccttttg ctcgtatttg aaaattgctg
    75901 ttttttattg acacggaaag agaacgtgtg ttctaattgt gttgaagagg tgattgttat
    75961 gtgggcgaat caaaatccgg tatttgttta tgaaaaagaa ccttcaagag atattttatg
    76021 tattgactgc aaatcttttt acgcctccgt agagtgcgtt gaaaaggatc ttgatcccct
    76081 tacaactaaa ttagtagtca tgtcctatcc gtccgattcg acagaaacac ggggtagcgg
    76141 attaatcttg gcttccagtc ctgcagcaaa aaaagcttac ggcatcacca atatcagccg
    76201 tgccagagat cttcccttcc cctatccaag tgatttatat attgttgccc caaggatggc
    76261 ctattatatg gaaaagaaca gagaaatcaa ttctatctat aaaaaatatg cagacgaagc
    76321 gaaccatcat gtctattccg tcgatgaaag cttccttgat gtaacaaata gcatggcact
    76381 ctttggtaaa acaaatgcgt acgacatggc taaactgatc cataaagatg tgtttgagca
    76441 gaccggaatc tacacgacta taggaattgg cgataacccg ctacttgcta aactagcctt
    76501 agacaatggc tcaaaagacg gaaagcaaat gtttgctgaa tggcgttatg aagatgtacc
    76561 agaaaagtta tggaaaatct cagatatcac tgacttttgg ggaatcggca aacgaacagc
    76621 aaaacgtctg aaacaaatgg gtatacattc tgtttatgat ttagctcacg cggattatta
    76681 tcacttgaaa agcaagctag gggtcatcgg tactcagctt tatgcccatg cttggggcat
    76741 cgatcgaagt tttttgggac aagaatatac accaaaatca aaaagtatcg gaaatagtca
    76801 aatcctagat agagattata caagacgaga agaaatcgag atcgttatca aagaaatggc
    76861 cgaccaagtc ggcactcgct tgagacgatc tgcagcaaaa acacaagtag tcagcttatg
    76921 ggtaggatac tctttaggct atcttgatcc aaatggcaag accgggtttc accagcaaat
    76981 gaaaatcgaa gcgacaaatg ctagcagaga tcttgcagat gctttattga ccattttcca
    77041 ccagcattac cactaccagg atattcggcg tgtaggcgtg aactgttccg acctcgtata
    77101 cgcgacaggt ttacagctta acctttttga agatcctgaa aagcagataa atgaagcgaa
    77161 agttgatttt gttgtcgata cgattagaaa aaaatacggc tttcaatcaa tcatccatgc
    77221 gcatagtctc ttgcaaggag gacgcgccat cgcacgtagt tctctcgttg gcgggcatgc
    77281 aggtggtatg agtggattag aaggtggaaa agatgagacg gacagcaaaa aaattcattg
    77341 actataacga gtatcgagat cggccatttg gattaaaatg ggggactgct tttgcgatgg
    77401 aagaactagt caacggtatc aaaaaaatga agaagaagca cgcaaacagc ctcttcctaa
    77461 acaacaaatg acattgcaag aaatcgatag tatactgaca gaagcctttt tatctcgtaa
    77521 agcagtaatc attcagctca atttaaaaga tgaatttgga agactcttgg atgaggtcga
    77581 agggcacttc attggtgaag cctatgaaga ttactttatg attgaccatc agccgatatt
    77641 gtgggaagac gtacggtata ttgagttaaa ggaaacaaaa aaatggtttg tgacatgaga
    77701 ggttgtgaca gaagtgatca acttcaaaaa ataagaaagg atttttcgaa aattgcttct
    77761 taaatttttg tggaattttg gcttattttt cgaagaagca acttctggaa caacgtatat
    77821 tagatatcag aggttgtgaa aaagtcgctt agttttgagt aacaagccaa ggcgctgatt
    77881 tcacaacctc tgtctatcta tccatctatt cggtaagatt catgcatgac gtcttcttta
    77941 tttagtatgt agagcccttt ttcttctgac cattcaacat aaatcagctg ttttacatct
    78001 gcatagcctt ctttcttcaa gttctccata agccatgctt cagtcaattg attggactga
    78061 agcactttat gctgaatttg cccttcatct acaagcagga tcgataaagc tttgtcttca
    78121 tctgattttt tcaatacact catttgaccg gcattctcta ggataacatg tttggcattt
    78181 tcaagaaaaa agcattcttg ctgtcttaag attgctcgca actgctccat ctcgatatgg
    78241 ttatttgtca actctgtcat gttgatgacg ccgtctttga ttagaacaga tggctcgcct
    78301 ttgacccaac gattgacctt ttcatttttt tggacgatac gttcgatacc ataaatcatt
    78361 actgcccaaa gcgcaatggc aaataggaca tgccctacat ggacattgtc atcataggtt
    78421 gattcttcta agatcccacc taaaacaagc gtatagacta aatcaaacgg tgtgatttct
    78481 gacatggatt tcttcccaag caaacgtacc actaataata aaccgatcaa cccgaacacc
    78541 agtttcattg taattgaaaa aatcattttt tctcccccta actatctgtt aattaaatta
    78601 tatatgcttt ctcacgaaca cgcatggaat atacaaggaa gaaatgtatc cttttactaa
    78661 aaaaaggact gtgacactgt agtgaccccc aaaagttaga cttttttgga gtggagaaat
    78721 ccactccttt tttttatgct ctaaaatgat atttttacac aaccgttacg gttgttttac
    78781 gaaattggac g
//
LOCUS       DADVXE010000006        76409 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.006, whole genome shotgun sequence.
ACCESSION   DADVXE010000006 DADVXE010000000
VERSION     DADVXE010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 76409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.006"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(1..526)
                     /locus_tag="KB913_000394"
                     /pseudo
     CDS             complement(1..526)
                     /locus_tag="KB913_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336126.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
     gene            complement(729..1208)
                     /gene="rlmH"
                     /locus_tag="KB913_000395"
     CDS             complement(729..1208)
                     /gene="rlmH"
                     /locus_tag="KB913_000395"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBB6818784.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            1636..2925
                     /locus_tag="KB913_000396"
     CDS             1636..2925
                     /locus_tag="KB913_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBB6818785.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(2964..3569)
                     /locus_tag="KB913_000397"
     CDS             complement(2964..3569)
                     /locus_tag="KB913_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBB6818786.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(3774..4238)
                     /locus_tag="KB913_000398"
     CDS             complement(3774..4238)
                     /locus_tag="KB913_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6818787.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(4260..4580)
                     /locus_tag="KB913_000399"
     CDS             complement(4260..4580)
                     /locus_tag="KB913_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBB6818788.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(4724..5803)
                     /gene="pepA"
                     /locus_tag="KB913_000400"
     CDS             complement(4724..5803)
                     /gene="pepA"
                     /locus_tag="KB913_000400"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBB6818789.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            6003..6353
                     /locus_tag="KB913_000401"
     CDS             6003..6353
                     /locus_tag="KB913_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBB6818790.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            6576..7523
                     /locus_tag="KB913_000402"
     CDS             6576..7523
                     /locus_tag="KB913_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6818791.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(7580..8998)
                     /gene="pepV"
                     /locus_tag="KB913_000403"
     CDS             complement(7580..8998)
                     /gene="pepV"
                     /locus_tag="KB913_000403"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBB6818792.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            9147..9992
                     /locus_tag="KB913_000404"
     CDS             9147..9992
                     /locus_tag="KB913_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBB6818793.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            9996..10436
                     /locus_tag="KB913_000405"
     CDS             9996..10436
                     /locus_tag="KB913_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBB6818794.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            10486..10680
                     /locus_tag="KB913_000406"
     CDS             10486..10680
                     /locus_tag="KB913_000406"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818795.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            10816..11493
                     /locus_tag="KB913_000407"
     CDS             10816..11493
                     /locus_tag="KB913_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6818796.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTRFRWLR
                     LTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDYFED
                     IQDRPIK"
     gene            complement(11901..12590)
                     /locus_tag="KB913_000408"
     CDS             complement(11901..12590)
                     /locus_tag="KB913_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818797.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(12565..14694)
                     /locus_tag="KB913_000409"
     CDS             complement(12565..14694)
                     /locus_tag="KB913_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBB6818798.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            complement(14742..16079)
                     /locus_tag="KB913_000410"
     CDS             complement(14742..16079)
                     /locus_tag="KB913_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBB6818799.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(16331..16690)
                     /gene="rplT"
                     /locus_tag="KB913_000411"
     CDS             complement(16331..16690)
                     /gene="rplT"
                     /locus_tag="KB913_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBB6818800.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(16743..16943)
                     /gene="rpmI"
                     /locus_tag="KB913_000412"
     CDS             complement(16743..16943)
                     /gene="rpmI"
                     /locus_tag="KB913_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBB6818801.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(17015..17539)
                     /gene="infC"
                     /locus_tag="KB913_000413"
     CDS             complement(17015..17539)
                     /gene="infC"
                     /locus_tag="KB913_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBB6818802.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(17583..17708)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            17859..18491
                     /locus_tag="KB913_000414"
     CDS             17859..18491
                     /locus_tag="KB913_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBB6818803.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(18493..19398)
                     /locus_tag="KB913_000415"
     CDS             complement(18493..19398)
                     /locus_tag="KB913_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6818804.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(19483..20142)
                     /locus_tag="KB913_000416"
     CDS             complement(19483..20142)
                     /locus_tag="KB913_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6818805.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            20458..21402
                     /gene="mvk"
                     /locus_tag="KB913_000417"
     CDS             20458..21402
                     /gene="mvk"
                     /locus_tag="KB913_000417"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBB6818806.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            21395..22372
                     /gene="mvaD"
                     /locus_tag="KB913_000418"
     CDS             21395..22372
                     /gene="mvaD"
                     /locus_tag="KB913_000418"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBB6818807.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            22385..23470
                     /locus_tag="KB913_000419"
     CDS             22385..23470
                     /locus_tag="KB913_000419"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBB6818808.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            23467..24531
                     /locus_tag="KB913_000420"
     CDS             23467..24531
                     /locus_tag="KB913_000420"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBB6818809.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(24780..25583)
                     /locus_tag="KB913_000421"
     CDS             complement(24780..25583)
                     /locus_tag="KB913_000421"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBB6818810.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25603..26445)
                     /gene="kduI"
                     /locus_tag="KB913_000422"
     CDS             complement(25603..26445)
                     /gene="kduI"
                     /locus_tag="KB913_000422"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBB6818811.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(26461..27468)
                     /locus_tag="KB913_000423"
     CDS             complement(26461..27468)
                     /locus_tag="KB913_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBB6818812.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(27475..28119)
                     /locus_tag="KB913_000424"
     CDS             complement(27475..28119)
                     /locus_tag="KB913_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBB6818813.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(28219..28977)
                     /locus_tag="KB913_000425"
     CDS             complement(28219..28977)
                     /locus_tag="KB913_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBB6818814.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(29104..30255)
                     /gene="fucO"
                     /locus_tag="KB913_000426"
     CDS             complement(29104..30255)
                     /gene="fucO"
                     /locus_tag="KB913_000426"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBB6818815.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(30337..30648)
                     /gene="rhaM"
                     /locus_tag="KB913_000427"
     CDS             complement(30337..30648)
                     /gene="rhaM"
                     /locus_tag="KB913_000427"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBB6818816.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(30650..31495)
                     /gene="rhaD"
                     /locus_tag="KB913_000428"
     CDS             complement(30650..31495)
                     /gene="rhaD"
                     /locus_tag="KB913_000428"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBB6818817.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(31509..32765)
                     /gene="rhaA"
                     /locus_tag="KB913_000429"
     CDS             complement(31509..32765)
                     /gene="rhaA"
                     /locus_tag="KB913_000429"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBB6818818.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(32762..34222)
                     /gene="rhaB"
                     /locus_tag="KB913_000430"
     CDS             complement(32762..34222)
                     /gene="rhaB"
                     /locus_tag="KB913_000430"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBB6818819.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            34375..35244
                     /locus_tag="KB913_000431"
     CDS             34375..35244
                     /locus_tag="KB913_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBB6818820.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(35370..36269)
                     /locus_tag="KB913_000432"
     CDS             complement(35370..36269)
                     /locus_tag="KB913_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6818821.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(36434..37258)
                     /locus_tag="KB913_000433"
     CDS             complement(36434..37258)
                     /locus_tag="KB913_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBB6818822.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(37269..38564)
                     /locus_tag="KB913_000434"
     CDS             complement(37269..38564)
                     /locus_tag="KB913_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBB6818823.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(38580..39059)
                     /locus_tag="KB913_000435"
     CDS             complement(38580..39059)
                     /locus_tag="KB913_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBB6818824.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(39065..40093)
                     /locus_tag="KB913_000436"
     CDS             complement(39065..40093)
                     /locus_tag="KB913_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBB6818825.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(40110..41216)
                     /locus_tag="KB913_000437"
     CDS             complement(40110..41216)
                     /locus_tag="KB913_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBB6818826.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(41445..44042)
                     /gene="adhE"
                     /locus_tag="KB913_000438"
                     /gene_synonym="adhC"
     CDS             complement(41445..44042)
                     /gene="adhE"
                     /locus_tag="KB913_000438"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBB6818827.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(44347..44727)
                     /gene="yajC"
                     /locus_tag="KB913_000439"
     CDS             complement(44347..44727)
                     /gene="yajC"
                     /locus_tag="KB913_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBB6818828.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(44824..45969)
                     /gene="tgt"
                     /locus_tag="KB913_000440"
     CDS             complement(44824..45969)
                     /gene="tgt"
                     /locus_tag="KB913_000440"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBB6818829.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            46187..46885
                     /locus_tag="KB913_000441"
     CDS             46187..46885
                     /locus_tag="KB913_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBB6818830.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(47053..49692)
                     /locus_tag="KB913_000442"
     CDS             complement(47053..49692)
                     /locus_tag="KB913_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6818831.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(50311..51342)
                     /gene="queA"
                     /locus_tag="KB913_000443"
     CDS             complement(50311..51342)
                     /gene="queA"
                     /locus_tag="KB913_000443"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBB6818832.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            51535..52710
                     /locus_tag="KB913_000444"
     CDS             51535..52710
                     /locus_tag="KB913_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6818833.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            52714..53355
                     /locus_tag="KB913_000445"
     CDS             52714..53355
                     /locus_tag="KB913_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6818834.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            53352..54269
                     /locus_tag="KB913_000446"
     CDS             53352..54269
                     /locus_tag="KB913_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6818835.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            54266..54937
                     /locus_tag="KB913_000447"
     CDS             54266..54937
                     /locus_tag="KB913_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6818836.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(55478..55966)
                     /locus_tag="KB913_000448"
     CDS             complement(55478..55966)
                     /locus_tag="KB913_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBB6818837.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(56167..56433)
                     /locus_tag="KB913_000449"
     CDS             complement(56167..56433)
                     /locus_tag="KB913_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBB6818838.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(56433..56696)
                     /locus_tag="KB913_000450"
     CDS             complement(56433..56696)
                     /locus_tag="KB913_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6818839.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            57172..57357
                     /locus_tag="KB913_000451"
     CDS             57172..57357
                     /locus_tag="KB913_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6818840.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(57499..59322)
                     /locus_tag="KB913_000452"
     CDS             complement(57499..59322)
                     /locus_tag="KB913_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBB6818841.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(59920..62625)
                     /locus_tag="KB913_000453"
     CDS             complement(59920..62625)
                     /locus_tag="KB913_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBB6818842.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(62931..63878)
                     /locus_tag="KB913_000454"
     CDS             complement(62931..63878)
                     /locus_tag="KB913_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBB6818843.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            64068..64337
                     /gene="rpsN"
                     /locus_tag="KB913_000455"
     CDS             64068..64337
                     /gene="rpsN"
                     /locus_tag="KB913_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBB6818844.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(64513..64875)
                     /locus_tag="KB913_000456"
     CDS             complement(64513..64875)
                     /locus_tag="KB913_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6818845.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(64886..66007)
                     /locus_tag="KB913_000457"
     CDS             complement(64886..66007)
                     /locus_tag="KB913_000457"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBB6818846.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(66023..66373)
                     /locus_tag="KB913_000458"
     CDS             complement(66023..66373)
                     /locus_tag="KB913_000458"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBB6818847.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(66503..68014)
                     /locus_tag="KB913_000459"
     CDS             complement(66503..68014)
                     /locus_tag="KB913_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6818848.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(68336..69688)
                     /locus_tag="KB913_000460"
     CDS             complement(68336..69688)
                     /locus_tag="KB913_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBB6818849.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(69841..70917)
                     /locus_tag="KB913_000461"
     CDS             complement(69841..70917)
                     /locus_tag="KB913_000461"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBB6818850.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            71113..72858
                     /locus_tag="KB913_000462"
     CDS             71113..72858
                     /locus_tag="KB913_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBB6818851.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(73138..73575)
                     /locus_tag="KB913_000463"
     CDS             complement(73138..73575)
                     /locus_tag="KB913_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBB6818852.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(73559..74932)
                     /locus_tag="KB913_000464"
     CDS             complement(73559..74932)
                     /locus_tag="KB913_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818853.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(75254..75742)
                     /locus_tag="KB913_000465"
     CDS             complement(75254..75742)
                     /locus_tag="KB913_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6818854.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(75764..76366)
                     /locus_tag="KB913_000466"
     CDS             complement(75764..76366)
                     /locus_tag="KB913_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6818855.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        21924 a        16311 c        13959 g        24215 t
ORIGIN      
        1 tcaacgatat tcttgtaagt aattatgccc caactaggat ttgtgggttc atttccatct
       61 ggagttaaaa aaacaaaaat ttttttatag ttagaataat tgcgttctat atatatttgg
      121 tatttattaa gttgccctcc agactccgaa gacagaattt tattttcgat gcacaccact
      181 attttatttt tttccgatac caataaaata tcaatattct tattttctct gtaaacaatt
      241 aaatcttcat agctattaag taaagcatca aaataattga tagcagcttt ggtatcatca
      301 ttagaatcta tatacctttt caaaaacatt ttaaaaaact catcagataa attgtgggtt
      361 tcatttggag caaacaaaaa agctaaaaaa ttactatgtc ttatttcatt tttagatagc
      421 ttaagtatct gaaatatatt tgttttccca gtccatttag atagttttct tcaatatcat
      481 ccatatcctc taatagattt tttaaacact ttttttcatc tatcatgttt tttctccttg
      541 ccattattct aactaaaatt ttacgtattt gtttctatgt ctacattatc tttttaacag
      601 tatctatttt tcttttgcaa cttacttggc taccaaagca aataaaaaag ttatttataa
      661 atttctccct accactacct attgctatta tttaaaatag ggataatttt ttctcttaaa
      721 aaatatcatt atttgtggta tggagccccc gcattgatcc ggaaggcacg gtagatttgc
      781 tcgacaagga tcagacgcat caattgatgt ggatacgtca tttttccaaa agagatctga
      841 gcattgcttc ttttcatgac ggcttcgctg agtcctaaag agccgccgat aacaaaaaca
      901 aggtggcttt ttccttggat acctaattgg tcgatttgtt tagcaaaaga ttcacttgta
      961 ggatttttcc cttcaattgc taaggcatag acgtattctt gttctttgat tttcgctaag
     1021 atccgttccc cttctttttc ttttacttgt ctcatttgcg cttcgcttaa attctccggg
     1081 gctttttcgt caggaacttc gatcaattcg atttttgcat aggcattcag ccgtttgaca
     1141 tactcattga taccttggat caggtatttt tcttttaatt ttcctactga gataattttg
     1201 atattcatgt tttctctcct ttggtcttca tgctcacttt gtttattata atcaattttt
     1261 tcgtctatat gtttattttg gctatttttg ttaaaaagat ttccccaaca gttatgcaca
     1321 acatccacag gtttatccac agaaaacagt gttattttac cttatttcat cacattcatt
     1381 aggcaaacat acgttttata agaatttatc cactttatac acaggctgtg gatatgtttt
     1441 atcccttatt tttccaatcc tatccgcgta gttttacaca gtatctgtgg aaaaagaaaa
     1501 tcaaatattt tcatctgaaa acaatgattt ttcctaaagt ttttcataaa aagttcacag
     1561 tctcaaagta gactaaagtc aacaaataag actatactaa cagtagataa atgaatgtaa
     1621 ttggaggagg aacacatgga tagaaaaaat gtgacaccaa agatgaaaaa aagtaaaaat
     1681 aatagcctct ggcgtaagtt aggtctgggg cttgttggag ggatcgttgg aggactactg
     1741 acagctggca ttttttatgc agcgatgggc actggcaaca atagttctac tgctacaagc
     1801 ggcaatcaga attctgccgg tgaaacagtt gtggaaaatg tcaaagtcaa tgtagattct
     1861 gatatcacca aagcggtaga taaagttcaa gacgctgtcg tttctgttat caacttacaa
     1921 agtcaaaacc aatcaagcgg ttttggcgga ctattcgggc agcaagaaga aagtagcagc
     1981 tcagatgata gtaatttgga agcttatagt gaaggaagcg gcgtgatcta caaaaaagac
     2041 gggaatactg cttatgtagt cacgaataat cacgtagtag atggccagca aggtcttgaa
     2101 gtcttgatga aagacggtac gaaggtaaaa gctgaattag ttggaacaga tgcttattca
     2161 gatttagcgg tgttgaagat caattcagac aaagtcgaaa cagttgcctc ttttggtgac
     2221 tcaagtgctc tgaaggttgg tgagcctgcg attgcgattg gttccccact aggatctgaa
     2281 tatgcaaatt ctgtcacttc aggaatcatt tcttccttga accgacaagt gacaagtacg
     2341 aatgaatcga acgaaacagt caatatcaat gcgatccaaa cagatgcagc aatcaaccct
     2401 ggaaattctg gtggtccttt agttaatatc gaaggacaag ttatcggtat caactcaagt
     2461 aagatcgcaa gtacttctga atctacttct aatgtaagcg tagaaggaat gggatttgct
     2521 attccaagta acgatgtagt gaatatcatc aatcaactgg aaaaagacgg aaaagtgaca
     2581 cgtccagctc taggtatcac aatggtcgac ttatctgccg tttctactca gcaacaagaa
     2641 caaatcttga agattccttc atctgtaact aacggtgtca tcgtgacaaa tgtccaaaca
     2701 gctacaccgg ctgaaaaagc tggattgaaa caatacgacg tcattactaa gatcgatgac
     2761 aaagaagttt cttctggtgt agaacttcaa tctgctttgt ataagaaaaa agtgggagat
     2821 tctgtcaaaa tcacttacta tgaaggctcg aaagaaaaaa caactactgt tgaattgacg
     2881 atcgatcaat cggcattaaa acaaaatcaa aatagtgaaa attaataaaa aagaggttgt
     2941 gacaaagact tgtcacaacc tctttatttt ggaaatgctt ctccgactac ggcatcctca
     3001 ggcaatacta agattccttt ttttgctgga gcatttggca aatgcaattc acgagcggaa
     3061 cagatcattc catagctatc tacccctcgc aaagttcctg gccagatcat cattccatct
     3121 ggcatcatag ctcctggttt tgcaacgaca actttttgtc cagcttcgat attgggtgca
     3181 ccgcaaacga tttgcaatac tgtaccattg tctacttctg tctcagtaat cgataaatgg
     3241 tcagaatcag gatgtgggac gcatgttttt acgtacccga caacgatctt cggttcatga
     3301 tcagcttcaa gctgttcttc gaatcctgct tctttgatca atcgattcaa tttcgctaat
     3361 tcctcatctg ttaagcttac ttggccgttc ccttcgattg ttagatgatc ggagatatgg
     3421 aaaaagttcc aagcaacaac ttgaccttgt tcatctttga tccgagcaac attccatttg
     3481 cgttcaacag tgttttctgt tcctttatcg tcggctataa taaccatcaa ggtgtctccg
     3541 acgtgtgctt tgttataagc aaaaatcatg ttctttcctc cattatcctt tgctgagatt
     3601 tatcttaaca aaaaattgca ttcactgcat gaaatttttt tcatgcttta tttccgaaga
     3661 agcctcttct ggaacaccat ttattcgtaa caagggactg tgacaagact tttgtcacag
     3721 tccctttact gttttagtta attgattaaa aaggtcgtac aagttccact tgcttaatta
     3781 cttggctgtt cttcttcgtc agaaacgatc aagacatcac aaggtgaatg acgtatcacg
     3841 tagctggcta cacttcctgt cataaagcgt tcgactgcat ttagacctga ctgcccaacc
     3901 atgattagat cgatctcata tttttttggc aatttgactg ccatggattc acgaacagaa
     3961 ccatatgcaa taattccttc tatatttgtg taatcaacag atttcccata ttctttacat
     4021 tcttcgatca tttccttggc tgtttcagtt tgctgatcga ctagattttg atcaataggt
     4081 gcatagccca taaagttata aaattgctga tcgattacgt ttgctacata tactttccca
     4141 ttattacggc gagccacttc taccgctttt ttgaaagcag caagtgcttg ttcactaccg
     4201 tcgataccta ctaaaatatt cttatattct tgattcatct tgacccctcc taacagatgt
     4261 cagccttttg ttacactttc taggaacgat tcgatttcct gttttgtttt acgatcttta
     4321 ttcactagac gacctaattc ttttccgtct tggatcacga caaaacttgg gataccaaaa
     4381 atgttccatt cagcggctac atctatgtac ttgtcacggt ctacttcaat aaattgccaa
     4441 tcagaaaagt cattttcaat ttcaggcatt tgcggtttga taaaacggca gtctccgcac
     4501 cagccggcag taaagaaaaa tacactcttt ccagtttcta cgtagcctgc taattcttct
     4561 aaactatttg ggataatcat tctttgtcct ctactttctg tttatgtatt tttcaattaa
     4621 attatacacc tttctttcga actaacaaac attgatcctc tttttataaa aaaaatctgg
     4681 caaaaagcaa tcttttgcca gattttatag tttcactatc gcattatttt ccgtatacga
     4741 tcgtatttac tgttgattta tccaaacctt tcagtgtttg aatcaacatt tctcgtgcag
     4801 cttcaaaatc gcgaatactg aacatcgttt gatgcgtatg gatataacgt cccactacgc
     4861 caatcactgt acttgggatt ccttcgtttt gtgtatgagc agcacctgca tctgtaccgc
     4921 cttttgaaac aaagtattga taagggatat tgtttgtttc agcgatatcc agcaagtact
     4981 cgcgcaaacg aggaagcatg atcaaacctg gatcttggat acgcatcaat gtaccttctc
     5041 ctaaatgtcc gaatgtgcca tttttcgtca ctgtatcatc tgctgcagag cagtctactg
     5101 caaagaacag atctggcttg aatttattga cagaagcttt agaaccacgc aagcctactt
     5161 cttcctggac attcgcgcct gcaatcaatg tatgacctaa tgtttcattt tgcaacgctt
     5221 ctaaagcttc taataccatt gtacagccat agcggttgtc ccatgattta ctgataatat
     5281 tctttccgtt ggctgttttg atcgtttcag cgtaaggaac gattgtgtct cctggaagga
     5341 caccgtaact cattgcctct tctcttgatt caaacccagc atcgaacaaa atatcggtta
     5401 cttctactga tttttgtccg cttgttcctc gcaataaatg tgggggaacg gaagaagaaa
     5461 tacatggata attcttacca gtagaggttt taagtgtaaa acgctgagca gaaacaacgt
     5521 aaggattcca gccgcctaga ggtacgactt taaaaagccc gttttcttgg atttgtgtca
     5581 gcatgaatcc gacttcatcc atatgtgctg cgaccattac acggggtgca tccgcttctt
     5641 catgatggcg cagaccaaaa atgccgccca aaccatctaa ctgtaactca tctaccagcg
     5701 gttccatatg actttccata taagcgcgaa catcttgttc aaaaccgctt gttccttgta
     5761 attctgttaa ctctttgatt cgttgaaatg ttttttcttc catatgctat tcgtctaaat
     5821 ttcagactaa actcctctca gacttatatt gatctgcgga taaaatatga ttttttctgc
     5881 agaccgatcg tatttattat agcttatttt ttctggtagc ggttatttat ttcaaagaaa
     5941 atatgagagt gtggtaaaat aagcacaagg agtaacaagt gagaagaagg aggtatgtcc
     6001 acatgtatga agaaagcgaa ctaagctatt ttaaaggcgg gttagcagtt ggaatcggtc
     6061 taggattatt gagcggggta gcttcaacga tttggtatca tcgcaaaaaa gtattgtcag
     6121 cagaccaagt acttgaaaat atcaagtcat cttttctaaa agaaggtgca atcgaaggtt
     6181 cttggatctc ttttgaaaag gaacctatta ggaaattcgc cgttcggtcg agtgcttatc
     6241 ggggaggtct ttctcgaata gaagatggcg aaactgttta ttatgaattt ttagcagatg
     6301 ctcatacagg aaccgtatta gaaatttcaa gaaaaaaagg tgcaacagat taatacgtca
     6361 aaaaagtgag agaacgaata cgcacccact attcaaaaga gaggtatcat gtccttcttt
     6421 tgtagtgggt ggttttttag atagagcttt ccaaacatat attccagtat tttcttttta
     6481 aataaatgat atttagcggg aaaaactagc atttcctttg attatgaggt atttttaatt
     6541 tagcttttgt tttctatagt taaggagagt gaaaaatgga acaacaagaa aaaattgctg
     6601 ttctgattcc ttgttacaat gaggaagcaa caatttcaac agtcattgca gactttaaac
     6661 gagaattacc agaagcagat atttatgtct atgataataa ttcgaccgat cgaacatacg
     6721 aattggccgt tcaaggtgga gcaatcgtaa aaaaagaacc tcgtcaagga aaaggaaatg
     6781 tgatccgcca aatgttcttt gatatcgatg ccgactatta tttaatggta gatggcgatg
     6841 atacttatcc tgcagaagct gtacatggtt tgctcgagaa attacgttct ggtgaagcag
     6901 atatggtcat tggtgatcgc ctatcaaatg gaacctactt tgatgagaat aagagacctt
     6961 tccacgattt tggaaataac cttgttagaa atacaattac tagaatgtat aaaacaaaaa
     7021 ttcttgatgt catgaccggc tatcgaggat tcaatcgtat ctttgtcaaa agttttccta
     7081 ttatgagttc tggttttcaa atcgaaacgg aattgacgat ccatgcttta gataaaaaat
     7141 tcaagttcgt tgaaatccca atcgattatc gtgatcgtcc tgaaggcagc gaatcaaaat
     7201 tgaatacatt ctctgacgga ttcaaagtga tcatgatgat tattaaaatg tttaaagatt
     7261 ataagccttt gcttttcttt gggatttgga ccatcttctt ctttttattt ggattggtca
     7321 cggggattcc tgtgattcgc gaatatatgc tgacaagctt tattacacgc atcccttctg
     7381 cgattttaag tactggattg atgactttag cacttctttc attagtaaca gggttgattt
     7441 tggatacagt cgtcacgaac gctaagaaag aatatgaatt gaatctatat catgtttatc
     7501 atgaatacca cagtagaaag taaaaaaagg atcaagactg caaaaataat ttgcaattct
     7561 tgatcctctt tttaattaat tatttcgcca aacgatagat ggcatctgca tagattgctg
     7621 ttgctctgaa caagtcatca agactcataa attcgtttgc ttgatgcatt gtatcagtat
     7681 atcctgggaa catcgctcca taagcaacgc cacgtttcaa caaacgtccg taagttccgc
     7741 caccgatgat ttgttcgtag cctttttctc cagtgtggtc ttcatagact tgcaataatg
     7801 tagccaccaa tggatcatcc attggtacgt aatgtggttc cattacgcga gcacctcgag
     7861 taactgttgc gccttcttgc cccactgttt gttcgatgtc actttgcaat ccgtctactg
     7921 ttacaccttt tggaaaacgg aaattcatat tgatgaagtt cgcttcctct gtaccatttt
     7981 cttcaaaagc aaatagtcca gcattcattg tcaatttgcc cattttttca tcttcataag
     8041 cgactcctag tttttctcca taaaaatctt catggacata agcagctgct acatggataa
     8101 attgtttagc agatcctagg aattcatagt tatctaagaa caatgccaag aaagaacctg
     8161 cattgatacc agattgtggg cttgcaccat gtgcgccttt accaactaat tcgattttta
     8221 catacgtatt gtccgcttca atcgttccgc ttactggatt tgcttcgatg aattggtaaa
     8281 atgcttcttc catcgcgata gctgcatctg cacttggtac ttgaagtgct gcagttgctg
     8341 ttcctggcac catattttcg cgaagtccgg aaacaaaaga tttcaagaca taatctcctg
     8401 cattgtcgcc tttgaagcgt aaagctaaag aaacatttcc tttttcacca ttgatgattg
     8461 ggaattcagc atctggtgag aaaccaaaat ctggttcttc ttcatgttcg aaataataag
     8521 ccatatcgcc ccagccgctt tcttcatcgc tgccgactac gaagcgaact ttttttgata
     8581 gtttcaagtc aagttcttta atgatcttca tcgcatagta agctgccata cttggacctt
     8641 tgtcatcgct tgatccgcgt gcaaagatct ttccatcctt gattactggt tcataaggat
     8701 ctgtgtccca gccatctcct gcaggaacga catccatgtg tccaaatatc cctagcgttt
     8761 cgtctccttc gccaagatca atatgccctg catagttatc gacatttttt actttaaatc
     8821 catcacgttc gccataagct aacatatgtt tcaatgcgtc gcgaggtcca ggtccaaatg
     8881 gtgcatctgg tgttactttt gagtcatcgc gctcgctgtt gacacgtaaa agatttttca
     8941 agtcttcaag caagtcttct ttacgtgctt ctacttcttt ttgccaatca attgtcataa
     9001 agttaatcct ccacttattt aagtcttcgt gttcatgata ccacaaatta cagaaaaaaa
     9061 tagttcaaaa aatctgacaa ttccttttct tatctgtttt tctctaaaaa aaatatacgc
     9121 tataatgagt aaaaggaggt ttttagatgc tgataaacga acaactagtg aaaagagtca
     9181 tcacacctcg tccaaaaatt tcacataaag gaacatttgg acgtatcgtt ttgattggcg
     9241 gcaatgaaca atatggcgga gcaatcatta tgagtgcttt agctgccgta cacagcggag
     9301 cgggtctcac gactgtagta actgatgaaa aaaatcggag tgctcttcac agtcatctgc
     9361 cagaagcaat gattgtagtt tggacggata ctgaccagtt tctttccgta ataaagcaag
     9421 cagatgtact cttgattggt cccggattgg gtacttcttc taagagtttg gaacgtttca
     9481 aacaagtact agaaaaccaa tcaaaagaac aatggctggt gattgatggc tctgctttaa
     9541 gtttacttgc tgctaatcat cttttgctac cctatcccga acaaactgta cttacacctc
     9601 atcaaatgga gtggcaacgg ttgagttctc taccgataca agaacaacgg gataaagaaa
     9661 acaaaaagaa gcaacaggaa atcggtgctg tgctcgtttt gaaaagtcat gagacaaaaa
     9721 tttatggtca ccagcacttc tacaccaatc ctttaggttc tgctgctatg gcaacgggcg
     9781 gcatgggtga cactttagct gggatgatca caggattttt agcccagttt cctcaaaatg
     9841 accaaacgat tgcagcagct atttatcttc atagtttcat tggagaccag ctggcaaaag
     9901 aacaatatat tgttttgccg acacaaatca gcgaagcact tccgaaatgg atgaattatt
     9961 tttgtaaaaa atcaatggaa aacgaggcat gagtcatgga gaaatttaca ggttatgtgc
    10021 gagaaccttt ttattatgaa acagatcaaa tggggattat tcatcacagc aattatatcc
    10081 gctggtttga agaggctcgg gtagccttat tggtacatct agggtttccc tataaaaaaa
    10141 tcgaagaatc tgggatcatc atccccgttc tggaagtaaa ttgcagctat aaagaaatga
    10201 tccattacgg agaaaaagtg agcatccatc caactatcca aaagtatacg gggacacggt
    10261 tggattttag ctacgaaatt gtgggaactg aagacaaaaa attaaaaact actggcagta
    10321 gtaaacactg ttttttactt tctgattcgc aacgattagt gaagctgagc aaagtcaatc
    10381 cggagttaga tcagttattc caagcgtacg cttctttgga tgatgtaaat tcttaataaa
    10441 gaccgtctaa gcatttttct tgtattgtgt cgagtagttc gtataatgaa aagaaaaaag
    10501 caggtgatcc ccatgtatgt cgttaaagta atgcacggtt acatcgataa aactggctgt
    10561 cgcactcggg aaaaaaactt agacaatctg ctcattttca aagacaaaaa agaatccgaa
    10621 gcttttgcta aaagaatcgg cggtcgtgtc aaaccgatcc aagaggtacg accagattga
    10681 ttcaatattt ttcttttcga ggctctaata ggcatgccta tcagggcttt ttttgcagac
    10741 tgtgttttta tgcccacacg atttgtaagc gatttatgtt ataatagatt atatctgcat
    10801 agaaaggaag gttaaatggt tatcaataat ttgcaacagc aagcttatga atctatacgt
    10861 aaacaaatca tttattccga gttagcacct ggaagtaaaa tctccgataa agtgttagaa
    10921 gaacaactag ctatcgggcg tacaccgatt cgagaagcac tgatccaact gcgcaatcaa
    10981 gagcttgtaa aaaccattcc acagtccggc acttatgttt caaaaatcga tatccgatct
    11041 gcttcattag cccgttatac gcgggaaaag ttggaaaaac cgatcctgca agaatgcagt
    11101 gcgaaaatga ccaagcaaga tcaagctaaa ctagaaaaaa tactagaaca aaccgatcag
    11161 gcagtaatcg ctcaaaataa aaaagctttt tttgatttgg atactgattt tcaccgaact
    11221 tgttatgaaa ttgctggaaa acgagaaatt tgggattggc tagaaagtta tagtacgcgt
    11281 ttcagatggt tacgtttgac gatttcagaa ttagactggg gtcgagtatt agatgaacat
    11341 cagacaatgc ttcaatcaat gattgatcat aactttgatg aagtcggatt tctttgcacg
    11401 atgcatttac atatgattat cgaggagcaa gaatacgtga ttcataatta ccccgattat
    11461 tttgaagata ttcaggacag acccatcaaa taagaggttt tggaatcagc gttttgacct
    11521 gagtattaga gaaagaaacg gcaaaatagt tcctcatatt ttgccgtttt ttttgagcta
    11581 ataccgaggg tcagctgatt gcacaccgtt tattgagagg ttgtgaaaaa gctgccctgc
    11641 atcaagtaat aagaacagcc aagtaaaaat agcttcttat gtttttaact tggctggact
    11701 tattaccgca gatgcaagct tttgaacacc gttttccaag aggtcgtgag cctgccgttc
    11761 atctccgagt cacaaggaac aatttcaaaa aacagcttct catgtttgtt gaatattttg
    11821 acttgtgacc gaggagttga caggagaaca tcgtttattc ggaaaaaaag gactgtgaca
    11881 cgacttttgt cacagtctct ttatttgtaa tctaaatcat actccgtaca tcttttttct
    11941 atttttttta tttcttctaa gatcccttgg ctacgaattt cattatatgg ccaaagtaag
    12001 actgcctcta atacataagg cgaaaaatcg ctttgattca tctcttttga aaaactcatc
    12061 gctgctatct cgctcaatgc acgaatgttt gattgatgtg tataaaaagg caaccgccac
    12121 agcacaattt tttcgctttg cgtataaatt cccttaacag aagcttcgat gtggtgaaat
    12181 agttcatgtc caataatcaa agcttgcgct gtttctttag agatcgaagc tagtcctgaa
    12241 cattttaatt tttctaacgg ctccgtcatc aatcgaatcc cttcatcttc tgcataagtt
    12301 gcaaaagtga ttcgttcgtt tatttgctct gattcacagg aaacgattgg aacagccatt
    12361 tgttcacaaa tttctcctac atcggcaaaa gggtactttt ttttgatgct acatgccgtt
    12421 tcgataccac aatcgattga ttgttgtata agaattttct gcttggacaa aggaatcttt
    12481 ttccaaaata aatctcgccg aaactggtag aatccccaaa tttcttcggg gatctgttgt
    12541 aattcgttta gtaactcttc taacttatgt ttgtttgata tttccggcaa cgacgatcac
    12601 ttcttcctcc ggttccatag tagatacttc cagatccatc aaaagctgta gttgttccag
    12661 atccgtcgct gtaaaatcag agactcttgc tcctaagcag agataaaatt ctggtcgggc
    12721 aatcaattca gtttgataaa ctgccatatc ttcccaaagt tgttcgacag ctgtcatata
    12781 attggctgca gttgttttca tacatgaagc atgtccacgt tggaccttga taaatccttt
    12841 ttgatcgatg atccgaagac ttccagcatt ttttgaacga ttctgttcgc cgcatacata
    12901 aaagaaaggt gtattttcca ataagcaaac ttcattttta tttaatcgca tatcctctgc
    12961 agcaagctct agtgcttctt ctgttgtgat ctccttggtt agatcggttg ctttcacttc
    13021 cgtagaacca gtagcgatag ccgttacttt tgaagtctgt ggatcgattt ctacgtggac
    13081 ttcgatcgat tctggtgtag cgcctgattc aatcgcttta ttcatcgctt catttttcaa
    13141 cgatcgtata tcttctttac ttggcgaagg gatgatacgt tctacaacat ctcggaccat
    13201 tgcaagtgct acaccaatag aagaaatcac ttcggcgttt tcaggaatcg aatatttcac
    13261 acccatttta ttactaaagt aagtaatcaa tgaggcagcg ccgcccccta cacctacaag
    13321 agaaatctga tctttctcca agtgatactt gtctgccaat tctaaaatca ccggttcaat
    13381 cttagcatag gatttttcca tgatctgttc tgcgatgtct tcaaccgtcg tatgacaata
    13441 atcagctaat gcttggatgg cttttcgtgc agatgggaca tttccataag aaaaatgttc
    13501 ttcttgcact aatccaagga cattggctgc acatgtattt gtaatagtca cttcttctcc
    13561 gtcttccatc actaccttga cgtaatcagc agggtctcct tctttaggag agaaaaattc
    13621 aaccttagga cctttgattt tttctgtctc cgtaaatact gcataatcta gaccggcaat
    13681 atgtgcagaa cgtggaccga catcgatgat tcctgactga ttagcccgta ccatcgaacc
    13741 gcctgccaca cctagaaccc gaacatctaa tgaagagata tatgttgggt ggccacctac
    13801 aattgaataa tcgattgctg gacgtccatt tttaatgacc ccgatattgg ttgttgttcc
    13861 gcctacttca aaataaacac cattagacgc tctcaagtac atcaaagagc ccatgactga
    13921 tgctgctgga ccggaaagca tggttaaaac aggtcgtttt ttcatttcat tgatttccat
    13981 tactccgccg tctccgcgca taatcatcaa agaaacattg acccctgctt ctcgtacgga
    14041 atcttctgta gaggttgccg tatctagcat ttttggtaaa atagatgcat tgattgctgc
    14101 tgtccgagtt cttcttgtca atccatataa ttttgtgatg tcagaagcca tcgttgtagg
    14161 gatcgatttt accgatgctg cttcataaac aactcgttct ggttccccat tatctactcc
    14221 aaatgccata gaagaaacca agacctccgc tctttctctt tctaaagaag aaatcgtttc
    14281 tgaaacacgg tctacattta agtgtttgac aggtaagaat gcattgacaa tctctatttt
    14341 tttcttattc cctaaatcga tatcgttcaa tctagtttgt cgttttgcta aaaaaccttc
    14401 taatccacct tttgccatcc cgattacgcc gacttttgct acgtctcctt caatcagtgc
    14461 attagtcgct tgtgtggtag aatgtgcaac aaacacaaca tcttctggac tgatattatt
    14521 ttccagcaaa caattttgaa aagactgaac gacacctgcg gctactccac ggacatcatc
    14581 gtgggttgtt ttcactgaag attttccgat gatttcgtgc gtcgcattat cgattgcgac
    14641 tgctttcgta tgtgtaccgc caacatcaat tcccattcgc acaaaacgtt tcattttctt
    14701 ttcctccatt catctaatcg tttttatcga cgttttgttt actaggcgtt cccgtacaat
    14761 aagaacgtga tcaggcataa gatcgctccg atgatccaac cagttgggat ggatttcttc
    14821 atatattctc gagaagttac ttttgtataa cctaatcccc aagcaaccca agattgtgta
    14881 atatctaaat gctgaggagc aatcgttgtg attgcaaata acgggaacaa aaaggctggc
    14941 gacatcgttg gattaacagc taatacgaca gctaaaatag ctgagcctga accgactaga
    15001 ttcattggac cgcggaaaaa tcctagtggt gtcaatatag caaatacgat tgccaagact
    15061 aatggtgatt gcggtatcca atctccaaaa atagctgaaa aataaggaga agcatacgca
    15121 gctgaattat tgaacatcgc taaggtcatc aagaaaccaa ccattggcgc aacatctact
    15181 gcgccatctg taaataattt cgcaaactga cgacagattt ctttataacc tccgcgcaat
    15241 tttccagtaa acagcaatgc ccagatacct gctagaataa aacctaagat gattggaaga
    15301 tctaaaagaa cgacccctaa aactggtaat aatacggcta accatgagat cattggtgcg
    15361 tcgccacctt cagctggtac gtttgctgcc attgcatagc gtttcttttt gttcattgat
    15421 atattagcga ccgttagtac cacaactaag cttacaatca tcccaatcat accaatttgg
    15481 aaatagtcat tataagtata gctttcagcc gctggattga aaccagcata aatcgtttga
    15541 tattgtttga aattgacgat attagcaaag attccagcca taatcgagcc cataaatgag
    15601 aacagtgcaa ccggtactga aatacctaat gacatcaaga ttggcaacac aataactgca
    15661 atagaaatca ctggtccgat tcctgtcatc gacatgaata taacagcggt tacaatacat
    15721 agtaagctca tcgtgattct tggcttgtcc cctccaagtt caactacctt tcgaatcagg
    15781 gtagctgcga ttccgctatc tactagaaca cgcccgaaaa aggcaccaaa gaagacattt
    15841 accaagatcg atttggcgta ctcagctggc cccgtcgtat agatatgcgt caacacatca
    15901 attactcctt gcccttccat cgccgggttt ggtgaaaacg tgtttccgac tagcgctaat
    15961 cccatccata cagtagccat gatggcaaag ccgaccatca agttgtagcc ttttacacag
    16021 taccagacca tgaaaaagaa tgagataact aacaaaatac caataataat atcactcatg
    16081 ttattcctcc gtccattttg tttttctgat aagcaaacta atatatcagt caaactcatt
    16141 ctaacttatg tagttagcgc tttcattaaa gggtgaccat aaatgttcag ttttcaatta
    16201 aaaaacctta attatgctat tttagactta tacgttattg tcctgtttca tttgatggag
    16261 gattgtaaat aaaaaaagag gaaagaacat aacttttcgt tatcttcttt cctctttata
    16321 attgtttagc ttatttagcc aaagcttctt ttgcttggtc agccaatgca gtaaatgctg
    16381 ctgcatcgtt aacagccaag tcagctaaca ttttacggtt gatgtcgatt tcagcaactt
    16441 tcaaaccgtg cattaatttt gagtagctca agccattcat acgagctgct gcgttgatac
    16501 gagcaatcca caatttacgg aagtcgcgtt tcttttgacg acgatcgcga tatgcgtagt
    16561 tgtatgaatt cattacttgt tcttttgctg ttttaaataa agtgtgtttt gaaccgtagt
    16621 aaccttttgc taattttagc actcttttac gacgtttacg agttactgtt ccacctttaa
    16681 cacgtgccat gtataattcc tcctaataaa aataaatctt cagattctgt tatttgtact
    16741 tcttatttca tttttgctag ttgttggcga atacgtttga agtcgccact agaaaccatg
    16801 cttgctttac gcaattgacg gcgttgtttt tttgttttgc cgtggaaacg gtgacttgta
    16861 aacgcgcgga agcgtttcaa tccgccttta ccagtacgtt tgaaacgttt tgctgatccg
    16921 cggtgtgttt tttgttttgg catgactata tttcctcctc aaaatctttc gttatccgac
    16981 tatcggctgt ccaacagcca gttagtcatt caaattactt actgtcgttt ttcggtgcca
    17041 gcgtcaagaa catgctgcgt ccgtccattt tcgctttttg ttccactgtt gcaatatccg
    17101 cagtttcttc agctaagcga ttcaagactt tttgaccaat ttctttatgg gtaatggcac
    17161 ggcctttgaa acggatagaa gctttcactt tatcgccctt ttccaagaac ttacgtgcat
    17221 tacgaagttt tgtattgaag tcattcaagt cgatcgtagg acttaagcga acttctttta
    17281 cattgatcac tttttgtttt ttacgcgctt cgcggtcttt cttttgttgt tcgaaacggt
    17341 atttaccgta gtccatgatt cgcgcaactg gtggtttcgc accaggggca actaacacaa
    17401 gatccaagtt tgcttgttct gcaatattca atgcttctgc ttttgtctta actcctaatt
    17461 gctcaccatc tgaaccgatc aatcgtaact ctcgtgcacg aatgccgtcg ttaaccatca
    17521 tatcctttgc tatggtcatt cacctccaaa tattatgaga gaaagaaaag cttaccgaat
    17581 aaacggcaat aaaaaaacga gttctcttac agaacccgcg cgtacttcac ctaatagaac
    17641 cagtgaaaac tatctagccc agtgacatta tcaactaagg cgagaagcgg gtgcttctgc
    17701 ttttatttct caaccatcat agtatagcaa aaactaatct ttttgtcaat gtttttcata
    17761 cagtttgtct tccttttctg aaaatgatta gattagcaga ctttctagca gtgattcccg
    17821 cttctttgct atactaaaga aaaacgaggt gaacccacat gaaaaaaatc gaacctattc
    17881 caccttctct tcctcttctt acaaagggag agttttattt agaagatgag gagatcttct
    17941 ctggtcttct gatcaacggg ggtgaccaaa gctatctcga tgccaaaaat atggtattaa
    18001 gagagagtca tatccaaaaa cttacgatgc aaaaaacagt tttacgtcat tttgaatgca
    18061 gtaatgtcat ttttgaaaaa tgtgattttt ccaatctgga gtggattggt ggcagtttcc
    18121 accaagtcgt gtttcatcaa tgtaaattaa caggtacgaa ttttgccgaa agttatcttc
    18181 gagactgtac tttcactgat tgtattgctt cgatggcttc ctttagtagt acaaacttga
    18241 aagctgtctc cttcgatcat tgtcaattag aagacagcga attttatgag gtcacttgga
    18301 aaaacctttt tttgtctgac aatcagttga ccggttcgaa ctggtttcga acttctctga
    18361 agggattaga ctttacgact aatttcttca cagcaatcgc tttatctcaa gattctttgg
    18421 cgggactaat cgtcaaccaa gagcaagcac ttgtgatcgc ccaagccctt ggtttgcaga
    18481 tcaaagacta gatcaacgaa tccgccgcca cagtgcaata agcatccaaa tagataagac
    18541 caaactgatg atcaaggcga ttccccatcc gaaaacggaa tgggtaaagg gtaactggag
    18601 attcattccg aagaatcctg tcacaatagt tggaacggtc aagatcagcg accagaccgt
    18661 caaaaatttc atcgtgtcat tcaagttgtt attcagcaaa ttattataag tgccagagag
    18721 ctggtctaaa atctgcgaag ctaagttcgt catttcaact gcttgtcgtg cttcgatcag
    18781 cgcatcgtcc aactcttctt tttccttttc tgacaacttg cgataaatag ccaatgcctt
    18841 gatttgttct aaaagtacta cattttgttt tgttcctgta actaagtaaa ccaaaccgat
    18901 ctctaaatct gaaagttgca gcagattctt gttcgttgtt ttttctctta atttcagatt
    18961 aagccgctga cgttcactat tcacttcctc gattaaagga aaaaaggaat cagaaatcaa
    19021 aaacaatgta cgaaacaata aactgtatac actcatgtct ggcattcgtt ccaaaagcga
    19081 tcgaattagt cgaatcacgt actcggtatt cggcgtggta aatgtaaaca aaccgtcttc
    19141 ttttaaaata aaagcgatag gactagtttc ataatgatta tcgacttttt gctggtgcgg
    19201 aacatttgat acaagcagta acgcttcatc aaaagaatcg tactctacgc gcgcccgttc
    19261 atttttatct agagaataag tcagcatctc gtcactaatg ccatattctt cttttaagtt
    19321 tttaacagct agcacatcgt tttgctgtac attgatccaa aaattacggt cttgattaaa
    19381 atagtgtttt tcccgcatac tctatcctcc tgacatttgt ttccagtata aagaaaaaag
    19441 tcgctcaaat aaaggtttac cctttatttg agcaactgta aatcaaatgg ctactttggt
    19501 ttggcgaatc tctgctaatt tttcttcgat cattttcaag acttcttctt ttgcttgagg
    19561 atcttccaca aaattatagc ggtctccatc gatttggatt tttggacttt ctttgtattc
    19621 ttcataccat tgatcgtaac gtctgttcaa ttctttgtaa taatcgtata gacttggatc
    19681 aaaggacaat tgttcatacg aacgaccacg tttttcgata cgctccaaca tcgtatcaaa
    19741 agatacacga atatgaacta ataaatccgg atgtttttta tgggcagcat agggaagttc
    19801 ttccatcatg ttttccagca gttcatcata cacacgaact tctgtttctg ttgctcttcc
    19861 tagatctgca tttagatgga aaagcagtga atcttcataa atcgaacggt ccaatacatt
    19921 attgtcatct ttcattgctt gtttgatgct tgcaaaacgt ttattcaaaa aataaatttg
    19981 cagcaaaaaa gcatactgtt cagggtttgc ataaaataag ggcaagactt cattatcatc
    20041 aatcgattca taaaatgcct gactatcaaa gtgttcagcc atcatttctg ttaaacttga
    20101 ttttccggca ccaattgtac ctgctaaaac gatcacgctc atttacctcc agctcacttc
    20161 atcactaaat attgtgttta actccaacct ttttaaatat acccccaata tctagtagtg
    20221 tcaattgtat ttttttctag tcaaagaaga aaaaaagtca aaaaattctt aagaaaaaag
    20281 tgttttttct ttagaaaacg tattcttagt tttacttctg agatggtttt agtaaaataa
    20341 aggaggaatg ttttttgaga cccttagtgg acaaaaaaat tcgtgaagca gcgcaactcg
    20401 ttttgggcgc tttatttttt gcttaaaaat cacttttacg tgagaaggag ttagattatg
    20461 gcaaactatg gccaaggaga atcaagcgga aagatcatat tgatgggcga gcacgcggtt
    20521 gtttatggag aaccagcgat tgcctttcct ttctatgcaa caaaagtcac cgcattcctt
    20581 gaagagctgg atgcaatgga cgatcaactg gtttcttcct actattcagg aaatttagcc
    20641 gaagctcctc atgcattaaa aaatatcaaa aaattattca ttcacttaaa aaaacagcat
    20701 gacatccaaa aaaacttgca actgaccatt gaaagcacga ttcctgctga acgtggaatg
    20761 ggatcaagcg ctgcagtcgc cacagcagtc actcgtgctt tttatgatta cttagcattt
    20821 cctttgtctc gtgaaatact attagaaaat gtccagcttt cggaaaaaat cgcccatggt
    20881 aatcctagtg gaatcgatgc agccgctact agcagcttgc agccgattta ttttacaaaa
    20941 gggcatcctt tcgactactt ttctttgaac atcgatgctt ttttgattgt cgctgataca
    21001 ggaatcaaag gacaaacaag agaagccgtc aaagatgtcg ctcacctctt tgaaacccag
    21061 cctcatgaaa ctggacaaat gatccaaaaa ttaggatact tgacgaagca agcaaaacaa
    21121 gcaatcattg aaaattcacc agaaacgttg gcacagacaa tggatgaatc acaatcactt
    21181 ctggaaaagc tgacaatcag caatgatttt cttaatctat tgatccaaac agcaaaagat
    21241 accggggcat tgggtgccaa attaactggc ggtggacgcg gtggctgtat gattgcatta
    21301 gcacaaacaa aaacaaaagc ccaagaaatc agtcaagcac ttgaagatgc gggtgctgct
    21361 gaaacttgga tacaaggatt aggagtacat acctatgttt aaaggcaaag cacgcgcata
    21421 taccaacatt gctctaatca aatattgggg taagaaaaat gaagaactca tccttccaat
    21481 gaacaacagc ctttcgttaa cattggatgc attttataca gagacagaag tcatcttttc
    21541 tgatagctat atggtagatg aattttatct agatggcacc ttgcaagacg aaaaagcaac
    21601 aaaaaaagtc agtcagtttc ttgacctttt tcgtaaagaa gccggcctct cactaaaagc
    21661 ttcagtaatc agtcagaatt tcgttcctac cgcagctgga ttagcctcct ctgccagcgg
    21721 gctagctgct ttagcaggcg cttgcaatac tgctcttaag cttggattag atgatctctc
    21781 tctttcaaga tttgctcgac gcgggtctgg ttcagcttgc cgaagtattt tcggtggttt
    21841 cgtcgaatgg gaaaaaggcc atgacgactt aagttcttac gctaagccag tcccttccga
    21901 ttctttcgaa gacgatttag caatggtttt cgttttgatc aacgaccaga aaaaagaagt
    21961 gtccagcaga aatgggatgc gtcggacagt cgaaacatcc agtttttatc aaggctggtt
    22021 agattccgtt gaaggggatc tatatcaatt gaaacaagca atcaaaacaa aagatttcca
    22081 acttctcgga gaaacgatgg aaagaaacgg actaaaaatg catggaacga ctttagctgc
    22141 ccagcctcca ttcacttact ggtctcctga cagcttaaaa gcgatggatg cggtgcgaca
    22201 attgagaaag caaggcattc catgctactt tacgatggat gctggcccta atgtcaaagt
    22261 tttagtggaa aacagccatt tatctgaggt acaagaaaca tttaccaaat tatttagcaa
    22321 agaacaagta attactgcac atgctggtcc aggaattgcg attattgaat aaagggagat
    22381 ttttatgatt gaagtatctg caccaggcaa actctatatt gccggagaat atgcagttgt
    22441 tgaaacaggc catccagcag ttatcgctgc agtcgatcaa ttcgtgacag tcactgtaga
    22501 atctgcacga aaagtcggaa gtatccaatc tgcacaatat agtgggatgc ctgtacgttg
    22561 gacaagacgc aacggagaat tagttttaga tattcgggaa aatccttttc attatatcct
    22621 tgctgctatt cgcttgactg aaaagtatgc acaagaaaaa aacattcttt tatcctttta
    22681 tgatctgaaa gtaacaagtg agttagacag ttcaaatggc cggaaatatg gattgggttc
    22741 tagcggtgcc gtgaccgttg caacggtcaa agccttgaat gttttttacg cgttgaattt
    22801 atctcagttg gagattttca agattgcagc actagccaat ttagcagttc aagataatgg
    22861 ttcctgcggc gacatcgctg ctagctgtta tggtggctgg atcgctttct caaccttcga
    22921 ccatccttgg ctccaagaac aagaaactca gcattctatc agtgagttac ttgccctgga
    22981 ttggccaggt ctatccattg agccattgat tgctcctgaa gatttacgtt tattgattgg
    23041 ttggacgggt agccctgcct ctacttctga tttggtcgat caagttcacc gttcgagaga
    23101 agataaaatg gtggcttatc agcttttctt aaaaaatagt acagaatgtg tcaacgaaat
    23161 gatcaaaggg tttaaagaaa ataatgtaac gttgatccaa cagatgattc gaaaaaaccg
    23221 acaattactg catgatttat ctgcaatcac tggggtcgtc atcgaaacgc ctgctttgaa
    23281 caaattgtgt aatttagctg aacagtatga aggagccgca aaatcttctg gtgcaggtgg
    23341 gggcgattgc ggaatcgtaa ttgttgacca gaaatctggc attcttcctt taatgagtgc
    23401 atgggaaaaa gcagaaatca ctccactgcc gttacatgtc tatagcgatc aaagaaagga
    23461 aaaccgatga atcgaaaaga cgaacatgtt tcactagcta aagcctttca tgataaacaa
    23521 aaaaacgaat ttgacttcgt acggatcatc cataaccctt tgccgcaaat agcagtttct
    23581 gatgtcgatc taagtacaca ggcagttggg tttacactaa gcagcccatt ttatatcaat
    23641 gcgatgactg gcggaagcga aaaaacaaaa aaaatcaacc aagatcttgc aatcgtcgca
    23701 agagaagcag atttgatgat tgccactggt tcagtcagcg ctgccttgaa agtcccttct
    23761 ttagccgata cttatacgat tatgcgacaa gaatatcctc acgggaaaat cattgccaac
    23821 atcggtgcag ggacttctgt cgaaagagcc aaagaagcta tccgattgtt tcacgcagat
    23881 gccttacaga ttcatttgaa tgcacctcaa gagttggtta tgcctgaggg agaccgtgat
    23941 tttaccaatt ggaaagtact tattcaagaa actcaaacag ccattgacgt ccccctcatc
    24001 gtaaaagaag tcggttttgg catgacaaga gaaacgctca atgatctagc tgctttagga
    24061 gttcatacag ttgatatcag cggtcgaagc ggaacaagct tcacccagat cgaaaacgcc
    24121 cgtcgctcca agcgggaact gagttattta gctgactggg ggcaatcgac agtctcttca
    24181 ttgcttgaag caaatgaagc agacacttct atggaaatcc tagcctccgg aggtatccgc
    24241 aatgcctatg acatatttaa agccctttgt ctcggcgcaa atgccgtggg tacttcagga
    24301 accgtactga cgcatctgat gaatcacggc gtagaagaaa ctattatact gatgaagcaa
    24361 tggcaagaag agcttcgtct gctttatact atggtcggcg caacgaatac cgcggcccta
    24421 caccaacaat ctctgatctt ttccggacca gtgaaggatt ggtgcgaagc aagagggatc
    24481 gacttagtga agtatggaag acgcacagaa aagagcgtgg gacaaaagta aagaacactt
    24541 ttgtctcacg ctctaaacac gtacaaacgg cggaagtaaa agcaactcct tcggaaataa
    24601 gctgaaattc acaaaaattt gaaaagcaat tttcgtgaat tccttcttat ttcttggagt
    24661 taaatgcttc tgtcccagcc tcttttttcg aataaatgat gtttaatcag ctgtccttcg
    24721 gtattcgttc aatccgctga tttcacaacc tctccactaa acagtgtact aaagctcttt
    24781 taaggttgtt ttccgatata ggcaagtatg cctccgtcca catacaagac atggccgtta
    24841 acgaaatcag atgcgctaga agccaagaag acagatggtc cagccaaatc gattggctcg
    24901 ccccagcgtg ctgctggcgt acgtccaacg ataaattgat cgaatggatg acgttcaccg
    24961 ttttcttgtg tttcgcgtaa tggagcagtt tgcggtgtag caatataacc tggtccaatt
    25021 ccattacatt ggatattgta ttgaccgtat tcagaagcga tgtttttcgt cagcattttt
    25081 aatccgcctt ttgccgcagc ataagcactg accgtttcgc gtcctaattc actcatcatg
    25141 gagcagatat tgatgatttt accgccgcct ttttcgatca tatccggaat aactgctttt
    25201 gaaacgatga atggggcatt taaatccacg tcgattactt ggcggaagtc tgccgcatcc
    25261 atttcgatca tcggtgtccg tttgatgatc cctgcattgt tgactagaat atcaactgaa
    25321 cctacatctt ctttgatctg ttgaaccatc gcttgaaccg cttcttcatc ggtcacatcg
    25381 cagacataac cttttgcatc gatgcctgct tctttataat gcgctatacc ttcatcaact
    25441 gattcttgat tcaagttatt aaatacgatt tttgctcctg ctgtagctaa agagcgtgca
    25501 atctcaaatc caataccata gacagcaccg gtgactaatg ctacttttcc atctaaacga
    25561 aacatatcca tactaaattc catcattttc tctcccttat gcttatttta attgatccat
    25621 ttgcaccata tccatgtctg tataggtgat attttctccg cacattgccc agatgaatga
    25681 gtaattgctt gtacctacac ctgaatggat cgaccagctt ggcgaaataa tggcttgttc
    25741 attgtctaca actaaatgtt ttgtttcatc tggtttgccc atcatgtgga acacacgtgt
    25801 atcttcattg gcataatcaa agtagacata agcttccata cgacgttcat gtgtatgaca
    25861 aggcatcgta ttccaagcgc ttcctggttc taaaatcgta taacccattt gtaattgaca
    25921 gctttcgcat acatttggat ggatgtattg gtagatttta cgttcattca gtgtcaggcc
    25981 ttcaccagtc tccattggtt ttacttggtc gatactgatt tttacatttg gatatttatg
    26041 atgagctgga acagaactaa tatagaattt agctgggttt tcagcatctt gagaagaaaa
    26101 tacaacatgt cgtgtttctt ttccgatata gtatccgtct tgttttttca tttcttcttt
    26161 ttgcccatcg atctcgatga atcctggtcc accgatattg atcacaccta gttcacgacg
    26221 ctctaagaag taatcaacac ctagttcttt gtctaatgtg atttctaatt ctttttcagt
    26281 aggtgtcact ccaccaaaga tcattcgatc gttgtgcgta taagtcaaac tgattttccc
    26341 tggttcaaat accttttcta ctaaaaattc ttttctcaat tgttccgttg aataatgacg
    26401 gatatcttct ggactgtgtg tataacgtgt ttccatttct tgcattttct tctactcctt
    26461 ctatcgaatg atttttccag agccgcatgc taaaaattgt gcgacttctt cttgactaaa
    26521 ttggttgcag tccccatgga tcgtatgctt caaggcagaa gctgccgtag caaaatcaat
    26581 gatttcttgc ggagacatat tggataaaat cccatggagc acgccacctg caaaagcatc
    26641 tccgccacct actcgatcca cgattggggt gattctatgg acttgggatt ccacatattc
    26701 atggttcatc cacaatgtcc ccttcaattc attttcactt gctgaatgaa cggtacgctt
    26761 ggtcgaataa aacacctgaa tattcgggaa cttttcctgc attttttgat aataataaat
    26821 tagaggttgt tcttctgctt ctggcgcttt ctcgatacct aacaaataaa gagcatccat
    26881 ttttccagct gagcagatat ctactaaagg taaaagctga tggattactt cgctggcttc
    26941 ttgctgtgtc cataattttc cacgatagtt gatatcgaag ctgatcaggc agccagcttt
    27001 ttttgcagct tctatcacct gtttcgtcat tttttgccat tttttagaca aagctggggt
    27061 gattcctgaa acatgaaata tatctattcc ttggaataac tcctctagcg accattccaa
    27121 atgatccatt tcagcaaaac ttgatccggc acgatcatag atcactgagg cggcgcgttc
    27181 gccactacca gtttccatat aataagtacc tagtcttgat ccaccagata atacctgttt
    27241 cgtatctact ccataacatt gcaagtgctt tttgactgct tttcccaatg cgttatcagg
    27301 tacttttgta gcaaaaatcg cttcatgtcc gtaattagct aaagaaattg ctacgtttgc
    27361 ttcccctccg ccataatggg cagcgaatcg ttcacttgaa tcgatacggg ttccctgctc
    27421 tgtggacaat cgcaacatga tttctccgag tgtcactact tttcccataa gcagctacct
    27481 cttgatttct ttcatttttg ctgcatactg ttgcgcgact tccgttactt tgtcaaaatc
    27541 tcctgtagct gcgggtgcta aaaggttccc acctactccg actgttacga caccagcatc
    27601 gaaccactct ttcatattgt ccagactcac accgccagtt ggcatgatat tgacttgagg
    27661 catcggcgcc ttgaaggcag aaatgatact tggtccataa gcgcttccag gaaatagttt
    27721 gacgatatct accccgcttt tcagcgctgt tttgatctcg gtaatagtca tacatcctgg
    27781 taagtaagga atttgataca gattgcacat ctctgccgtt tcttgatcaa aggaagggct
    27841 aacaatatac tctgcgccag ctaagatagc caagcgagct gtgacagcgt ctaatactgt
    27901 gcctgcgcca atcactattt ctggttggtc tttgtagaat gacaaaagtt ctttgattac
    27961 ttgatctgct tgagggactg taaaagtcaa ctcaatacca gttagaccac ctttgatgat
    28021 tgcgtggcaa gcattcaaag cttcttcttt gctttttccg cgtaccaccg caatcactcc
    28081 ggcgtttttc aatcgagata aaatatcaat ttttttcatc ttctccacct atttcctatt
    28141 tagaaatttt attttataac ttggaaatct atacccatat tatacggcag aaaagaaaaa
    28201 ttgcaaacgc ttttttcatt atttttgaat tctttgctcg atttcgcttt ttgtttgctt
    28261 gagggcactg attatttgtt cttttgtctc atctgttaaa cgatatttcg gcatacttac
    28321 actaaatgca ccaatgattt gttcgttttt cacgattgag gctcctatac aaaaaatatc
    28381 acgttcgatt tcttcatcgt caaatgcgat gtgggtttct tttaccgttt tgatttcctt
    28441 tttcaaccgt aatgcattgg tgatcgtata ttctgtgtaa gggatcaacg gatgcttttc
    28501 aagataatca gtgtactgct cttcactgaa ttctgctaat acggctttgc ccatcgcaga
    28561 attgtataat ggtcgggtga ttccgatttt tgaagacatg cggatcgttt gatgttttgg
    28621 atctagtttg ttcacgtaca agatctcatt gttgtccaat acccctaagt ggatagtctc
    28681 atcgatcttt tgctgcagct gttctaaaaa cggtaaagtc aactctacca aatcgatttg
    28741 ttcaatgttt ttattcgcgt agcgaataag ctttgcacct aaacgatagt ttttctctga
    28801 atttttattt acgtagccga tcatcaacaa agtatctagt attttcaaga ctgtagaaga
    28861 ggtcattccc acaccctttg cgatcgtctg caaagagaca tcttggtttt ccgctaaata
    28921 gtctagtatt ttagaggctt tgatcaatac agttccataa ggctttttat tttccatata
    28981 atattctcct atttctttat aagaaaaatt atagcggaaa taccatcaat ttaaaagaga
    29041 tatccagata taaactacca tttctcttta caggcaattt aatgttgaag atccgcttcg
    29101 tttttacatc aaactttgat ataaagcaat gatttcttct actgtcgttt ctcttggatt
    29161 tcctggtgtg catacatctc gcaaagcatc ttctgcaatt gctggaatat ctgcttcttt
    29221 tacacctaat tcagaaatgg tttctgggat tccaaccgct ttgctcaacc gatcgatctc
    29281 accacaagcc gcttctctta catcttctaa agacatttca gctgctcctt taatccctag
    29341 aacaagagcg atctcacggt acttttctcc agtatattct ttgttatatt tcatgacagt
    29401 tggcaaaagt gctgcacacg ctacgccatg aggaatgttg taccatgcac ttaacgggtg
    29461 agccatcccg tgtaccagtc ctaaaccgac atttgagaag cccattcccg caatatactg
    29521 tcctaatgcc attttttctc gcccattttg atcgccatct acagaagctt ccaaagaatg
    29581 gccgatgatt tcgattgctt ttaaatgcag catatcagtc atttcccaag cgccttttgt
    29641 gataaaccct tcaatagcat gcgtcatagc atccatacct gttgatgcag ccaatttttt
    29701 cggcattccc atcatcatat cgctgtcgat gaacgcgacg attgggatat catgaggatc
    29761 aacacaaaca aattttcggt gatttacttc atctgtgatg acgtagttga tcgttacttc
    29821 tgctgctgtt ccagaagtcg ttggtatagc taatataggt aaacatggat ttttcgtatc
    29881 agcaacacct tctaaactaa tgacgtctga aaactctgga ttcgtcaaaa taatcccaat
    29941 ggcttttgcc gtatcgattg gcgaacctcc accgattgcg atcaaacagt ctgcctctgc
    30001 ctctttaaca aaagccactc catcttttac attttggatc gttggattag gtacgatccc
    30061 gtcgtataaa gcataagcga ttgctgcttt atctagaagt tctgttactt ttgttgctat
    30121 accgtgctcg atcaatcctt tgtcagtaat gacagctgct ttgccgaatc ctcgctgctg
    30181 aaattcaggg acgatcgact caatcgctcc ttttccaaaa tacgatgttt catttaaaat
    30241 cattcgatta ctcattttct attcctccta atttgtatta tttttcacaa taaaaacgaa
    30301 agaaccccaa gcaaccggtt gcccagttgc ttgttgctac agttcaaaga ctggcatcaa
    30361 ttcccaactg actggagagg catctggatt tgtctccatg atatcttcca tgtacttcca
    30421 ccatttttga ttgatagatg tatttgccat tttttcccat aacttttcat cttcgatcac
    30481 taagtaacca aataacaaac ttgtactcgg atcaagatag atcgaatagt cgatgacccc
    30541 gtgttcacga agtgctgtac gcatttctgg ccaaagttca tcatgtcttt ttttgtattc
    30601 ttcttgtttt tctgggtaaa ctttcatgca aaaagctttt ttcaccatgt cagacacctg
    30661 ctttcgtatg aacttcctcc aaataacctg cttttggagt gacaccaaac gcatctgcta
    30721 aatgccacag gttttcgtcc gtgattgttt gcaagattgg tccttgcgct ttgacgtacg
    30781 tatagacttc tgctgccttt tctgctgtct cgatcaaacc aaagacttca tccatgtctt
    30841 ttcctgaccc gtagattcca tgttgtggcc ataaaaccaa tcgagtttct ttcatttttt
    30901 cagctgttgc ttccccaatc tcatttgttc ccggaaccat ccacggaatg atggaaattc
    30961 cttctggaaa aacaactaag cattccgtac acatttgcca tagcgtacga ctaaaggaac
    31021 gttcgtctaa ttcatgcgta aaactcatcg ctaatagatg actagcatgg caatgcataa
    31081 cgatccgatt atctgggtct acttctaaac gggcgatatg actcatgaaa tgacttggca
    31141 actcgcttgt aggaaggcat tcgttttcca gcccccacaa aagttccagt gttttgccat
    31201 cttcagcaac tcgaacgatt ccaagattct cggcaggttc gctcgctaca tttttaaaat
    31261 atcttcctga accagttaca ataaaatagc atcctgctaa acggctggca tcaaaaatca
    31321 tcgagatgcg gcggatcact ttttcaggat ccaagaacgg tgtgatctct tcttctttta
    31381 gtaaataaga aatattcccg ccatttcttt catcccatcc caagcgataa agattcgacg
    31441 tcgtttcgat catttctttc acataaggcg cttgtaaaat atctattttt ttcaatatag
    31501 ccacactcct attttcttaa ttccaacacg tctttttgat attcctggac ttcttccagc
    31561 caatccaaac caactggaac ttgatttttg taacagaaat aattccatac atcggcatac
    31621 gggaaatctt tcaattcttc cgtataagcc attcttgaag taaagtcaaa agccagctcc
    31681 atttctttca atcgctcaac tggttccagc atagctttca gcagtgcttt ttgtgtattt
    31741 ctcgtaccga tgacccaagc agcgatacgg ttgatcgttg catcaaagaa atccagaccg
    31801 atatttgttt tttccaacaa ttcgttacgg actaattctt tagcgatttc ctgcaattca
    31861 tcatccatca aaaccacatg gtctgaatcc caacgcactg gacgggaaac atgcaacatg
    31921 attcctttgc tgaataaagc taatgaagat aatttattgg aaatcacttc tgttggatga
    31981 aaatgtccag catctagaca aacaagtttg tcacgagtca acccgtaacc catataaaat
    32041 tcatgggaac cgactgtata agcttcagcg cctaaaccaa atagtttgct ttctactgca
    32101 tcttgtacat accgttcatc taactcttct gtaaaaattt catcgagtga ttccattaaa
    32161 cgttcccgtg gggtaaaacg atcaatcgga ttatctttca tcccatcagg tacccaaaag
    32221 ttattgatac ttgtttgccc agtttctttc ccaaagtact ccgcgatttt gcggcttctt
    32281 ttcccgtgtt cgatccagta ttcacgaact tctttatctg gatgagccaa tgtaaagccg
    32341 tctttcatca ttggatgcga aaagaaagtc ggattgaagt caagaccgat ttcttctttt
    32401 tttgcccact ctacccattt ttcaaaatgt ttcggctcaa tttcatttag atcgacagat
    32461 tcttctgtat ccaaatagat agcatgaagg ttcaatttgt gtttgcccgg tatcaacgaa
    32521 taagccttct ccagatcttg tctaagctct tcaggtgttc gtgcggctcc tggaaaattc
    32581 cctgtcgcca tgattccacc ggtcaattcg ccatccggtg tcaagaaacc tttgacatca
    32641 tctccttgcc agcaatgcat agaaattttg atgtcctgta tcttttctag tacagcatct
    32701 gtatctacac cgatagttgc atatttttct tttgcttgtt cgtaatttct ttcaatcgtg
    32761 ttcatacgat tactcctttg attttattca cgtaccattc catcgtgttt tgcttatttt
    32821 catctgggta aaaagtttca catggaaacg actgtttgat tacatttctt gcttgttcta
    32881 tattcgaaaa ctgacctgta ctgagcattt gcatggcaac attcccgatt gctgtggctt
    32941 cactaggtcc tgcttctaca atgattccgg cataatctgc tgtcaattga ttcagtagac
    33001 gattattcga tccgccccct acgatgtgca gcttttccaa tttcgttcca gttaagtgtt
    33061 ctactttgat cagctcttgt gcgtaacaaa gagcaagatt atcatacaca caacgagcga
    33121 tagctcccga tgagacaggg actggctgct ctgtttcaaa acagtattgc tgaatctctt
    33181 ctatcatatt tgggggattc aaaaatcgag ggtcattgat ttccatcact tgctgcagcg
    33241 gtttttcttt tgcagcaagc tctgccaatt ccgcataact gtactcgtac tcttgcattc
    33301 gggcaacttc ctggatcaac cacatcccca tgatgttttt caaaaaacgc accgtgttat
    33361 gggcacccca ttcattcgta taattttcag aaaaagcatt gcgagaaaca ttggcgatct
    33421 ttgtttcaat ccctaaaagc gaccatgtcc cactgctgat ataaccccaa cgttctcctt
    33481 gacctggcgt tcctaataca gctgacgccg tatcatgact tgctactgtg ataaaggtca
    33541 catctggcaa atcatatttt gaaaattgtt ctttttgcag atctcctagt atcgttcccg
    33601 gctctgtcaa tggtggaaat aattccttcg agacaccgat tttttcaaga agttctattt
    33661 cccattcttt tgtccctgca ttcagcagct gcatagtaga tgcattagtt ttctccgtca
    33721 ccatgttacc agtaaagaca taccctaaat aatcaggtat cagtaacaat ttatgtgctt
    33781 ttgccaaatt ttctttttct tcagcaaaca attggaacaa ggtattgaaa ggctggatct
    33841 gaatccctgt ctgctcatac aacttatcta gagaatagat ttcagaaaac tgttctactg
    33901 ctccattggt acgcttgtcc cgataagcaa tcggatcatt tatccgatcc ccttgttcat
    33961 caatcagaca gtaatcgact gcccatgtat cgatccccgc aaaaaggcga tcaatccctg
    34021 tctgctttaa tttttcaaat ccaatcaaaa tctctttgat aagataatcg atcttccagc
    34081 gatcgtgacc gtctttgttc cgaaagccgt ttttgaaccg gtgtacttct tccaagatca
    34141 aagaaccttt tgcatccctc gtacttttca ttagtcgtcc gcttgatgca ccgatatcga
    34201 tggcaacaaa tgttggattc atttctccac ctcttttact ttattgttga ttagcacttt
    34261 attaataaag cgttatcatt tattgacaat gctatcataa tacagaatct tatattttgc
    34321 ttcacactat tttggtatat aattgcatta tcttgacaag ttgggagtgt ttacatggat
    34381 tactgggaaa aagccaacca ctcatggtcg gaagactcaa aaagagtgat cttgacgcct
    34441 acacaaagaa gcaggaattt atttttttat atccaagaaa tcggttactt caaagcacca
    34501 atcccttact atactgaacg agcacattta ccttcttact tgataaagtt tactttgtct
    34561 ggcaaaggtt cgcttacata taatgataat cagcaacagc taaaagctgg agacttattt
    34621 tttattgact gccaagaata tcagcgttat caaacgatca gcgaagaacc atgggaaatg
    34681 gattggatcc atttgaatgg tcagaacgtc caatcatttt atcaggagtt cacaaaagac
    34741 ggccataaca ccttccattc aacaggagat ccatcagaaa acaagatcca ccatttgatc
    34801 acagaattga tccacatgca acaaggcacg aatgcccgta ccgatttcca gtcctctgta
    34861 gctatccacg agttgctgaa tgaactgatt ttgcaaaagt atcagctaga tttcgaagaa
    34921 gaggatattc ccgcctacgt ttacaaactg aagcaatact tagacgaaca tttcaaagaa
    34981 acgattacac ttgatcaatt agaacaacaa ttcttattga ataaatatca gctgagcaaa
    35041 gatttttcca aatttatcgg ttctccacca atcgattatt tgatcagcaa aaaactttct
    35101 tacgctaaag accttcttcg gtatacagaa tttacggttc gaatgatttc cgaagaaata
    35161 gggattgaga attttgctta ctttagccgc ctgttcaaag caaaaacagg actatcgccg
    35221 agagactttc gtaaattcag ctgattcata taatatgtac gtcatttttt caaaatattt
    35281 tgaaatatat agataaaaat aaaataaccg cagtttctgc ttctatgtaa acaacagcag
    35341 ctactgcggt tattttttag tgatcattct cattgttcat cttcaaaatg ttcataatga
    35401 accaactgtt tctgtgtatc acgtttcaaa aattctttag gcgttatgcc gaactctctc
    35461 ttgaatgctt tcagaaaatg cggataagaa gaaaaaccac ttttactata tacagcacta
    35521 gagctgcggt attctcgcaa caagtgcttg gcatagatca gctttttctt cattacatac
    35581 tgatgaaacg taaatccagt gtacttttta aattctcgtg tgatatggta tttgctgaca
    35641 aaaaactgct tttccatttc ctctaaagaa agcggatgag ataaattttt tgagatatat
    35701 tgtaacattt gttccacacg ctcattagga actacagcat tctgttcttg cgcactctct
    35761 tctttttgta caacttgatt gagaaaaatc aagtattcta ccagagcttg ttcatatttt
    35821 atgtcttcac cgtaaatttt tttatcagga ggatggtcga taaatgataa tttttgcttc
    35881 aatacttcct gttctatttg caatacacga ctcctcttct ctcccattgg ttgaaaacaa
    35941 gccgatagat tagaccatgg cgtggaacga ctttctagaa aagaaggggt gacaaagata
    36001 tagacacgct cgaatacatc tgaagattgg cggacgatac gatgcaaatc attggaatgg
    36061 atgagcagca cacttcctgc tttgatcgta aattgtcgtc cgttcaaata aaaagtcgct
    36121 tctcccttta atgtagcatg gatctcatag aaatcatgat gatgatagat cgttttattt
    36181 tggctgacga catctttgac atgatagatt tcatactgat cagaaaccat cgtattgact
    36241 tgttcaccgc tgattttctt ttggagcatg tgccgcacct ccttttgttc acttatgcac
    36301 aattttatta taccacgttt tttgtaatca aaaagagctg cttttatata ctcttataaa
    36361 aaagaagaga cgtggcatct tctagccccg ccccctccat tctaaatatt agttaaccaa
    36421 cgtcttcttt acattattca agaagacttc ttccataacg aatcccatca tcttttgttt
    36481 cttcaagaac cacatacagg tacggacgat tcttcatgat gatttctttg atttttgtgt
    36541 actcgatcac accgtctccc aaatttaccg gcacgatttt ttcctgttcg acacgaaaat
    36601 ctttcaaatg aaccgcacat atcttttcac caaaacgttc aaaagcttct tctaccaatt
    36661 ggacttgttc ttgataatca ctacttgtga tcaaattggt cggatctaaa atgattccta
    36721 gatagtccga atctactgct tggatcagct gctctaccct tgctaaagaa tacaccggat
    36781 gattcaaacc tggttctatc cccaccatca tttggtattt ttctccagct tttaccaagc
    36841 gacggataac ggacacagct tcagcaaatg cttcatctgt gaaattttct tccgtatatt
    36901 ggatttccgg caaaacacat ccagtttccg aagcaaccat cgacgcacca aaggaagaag
    36961 catagcgaag atactgctcg aactttgtca gcaactcttg tcgtatcgtt aaatctggat
    37021 gaatcatatt gatatagcaa cttaaaattc ctacggtcac ttcttgcttt tctaaaactc
    37081 gtttgacata atttcccatc ccagaattga tctcatttgc gccagaaggt atttcaggaa
    37141 acgaaagacc taaggcgagc tgcagtgtat gaatcccttg ttcttttgtt ttttctgcaa
    37201 gatcttctat cgtttggact tcggaaagat catgtcctct aattgtaatg ttcaacataa
    37261 ctattctcct aactcagcat attgggtagc cacatgacga tttgcgggaa gtaagtaatc
    37321 aaaaacaaga cgactaagat aaccccataa aaaggaagaa gcggtttcag cattgcctct
    37381 gcttttacgc ctcctacact tgcaccgaca tatagtcctg tacctactgg cggcgtgatg
    37441 gagcctacac acagattcat gattgaaaac aacccgtaat gtacaggatc aacccctaca
    37501 cttgtgacga ttggtaaaaa tattggtgta aaaatcaaga tagcaggcgc cacatccata
    37561 aacataccca ccagtaataa cacaagattg actaataaca gaataataaa tttattatcc
    37621 gttacgccca taatcaacga actaattgcc tgaggaatac cggtaaacgc catggcgaaa
    37681 gacatcatgg aagaagtagc caataagaac atgatcgtcc ctgacattgc tactgattga
    37741 aacaacatat taggtatatc ttttagtttt accgttttat agtaaaacat agcaatcaac
    37801 agggagtaaa tgacagctat cgctgaagct tctactgctg taaatatccc cgtcaagata
    37861 ccaccgataa tgatgacaat caatagaagg ctaggaatcg cctcttttat tatttttcca
    37921 gcatgagcca tctgtccttt ttcgacaaca gggtatttat tctttttagc aacgatgaat
    37981 gctactagca tgattcctag cgcccacaaa gcgcctacga gataacctcc cataaacaaa
    38041 gcagagatcg aagcaccacc agcaacaagt gaatacatga taaaagcagt acttggagga
    38101 atgaccatac ctgtcggagc tgacgcgata ttgaccgctg tcgcaaactt ccggtcatat
    38161 ccttcttcca cttgctgagg gatcaacact ccgccaatcg cggtagaagc ggcaatggcc
    38221 gagctagaga tggaaccaaa taaagcattc cctaacacat tcgtatgagc caaagccccc
    38281 ggcacgcgcc cgacgaacaa catcgcaaaa tccactagtt tcttagctat ccctccatta
    38341 ttcatgataa tgcccgagag aacgaaaaac ggaatagcga tcagcgaaaa actattgata
    38401 cttcccacca ttttttgagc tgaactaaaa gcagaaacat caaacggtat aactaacaat
    38461 aaagtcatca tcgatgagaa tgcaatactt atagcaatcg gcatccctaa tacaagcaac
    38521 acaacaaata caaaaaataa cactaatccg gcttctattg ccattttatt cctccatttt
    38581 tatatttttt cttgaattgc tggcttgttg cttaatgtat cgattagatt gatcaggcta
    38641 tagataatga tgagtacccc cgatacaggt actgacagat aaacatatcc cataggaata
    38701 cttaaagaag gcgagatctg ccccattgtc aatgtgacag cattccatcc gccatacacc
    38761 atgatcatcg cagcaaatac cagaaataaa ctttgaacaa caacttctaa aattttactt
    38821 tttttgccag ttaatttttc acttaaaacc gttacggcta aatgtgcttt ttgtcccaca
    38881 acatacgcgg aagacaacat ggcaaaccag acaagaccga atcgaacaag ctcttccgtg
    38941 accgtatttg gatttcctaa aaccgttctg gaaaatactt gccataaaac aacagcgacc
    39001 atcccaacaa gcaaaacagc tcccaggatc tctaatacct tgtttaaaat cattttcatc
    39061 acagctacgc tccttgctct tggatctttt gataaaggtc tttgtaggta ggatcgtttt
    39121 tgaatatatc atgaagtggg gcaactgcct ctcgaaacgg tgtattatct acatcattga
    39181 attggactcc atgttcttct tgtgctaaag ctttttcttc ttcaattgct tttgcaaaag
    39241 cttcaatttc aaaaaccgtt gattctttcg ctgcttcttc aatggctttt tcctgctcat
    39301 cagttagctg ttctttgatg gcatcattca tgatgatgat atctggcaca cgtgtatgct
    39361 catcatagga atagtattta gccacaccac catgtccagc tgtatacaag acaaattcat
    39421 tgttttctga tccgttgatc aaattggatt gaagagacgt gtacacttca tcacttccca
    39481 taggtacggg cgaaccgcct aaaagctcta ccattttgat agcggtttcg ctttgcatca
    39541 cacggatctt ctttcccttc aaatcttccg gcgtatggat cggaccgtct accatataaa
    39601 agctgcgctg accagaatca taataggtca atccggtaaa tcctaaattt ttggtcgatt
    39661 ggtagattgg ctccattatt tcttcattat ccatcacctt aaagaaatgt tcttcatcat
    39721 tgaatagata aggaactgaa aaaatcgaat aatctttaga gaaactttcc aacgctgagg
    39781 cacttacttt tgtgaaatct actgctcctg actgtgtcaa ttcgatcagt tcacgttctc
    39841 cacccagttg tccatctggg aaatactgga tctgtacgga accatctgtt ttttctttta
    39901 ctaaacgccc aaattcattc attgcatcaa ttactggctg gctgttgctt gcataagcaa
    39961 agcgcaaggt aactatctca tttacatctg catctgcgac agttgccaca ctagaattat
    40021 ttccgcagcc gcttagacct agcagaccta ggctaagcga acttgctgca aacagcagtg
    40081 atgttttttt catatgggtt tcctttcttt taacaataag agacgagcaa ttctgtcaaa
    40141 caaagcaccg ttaacgactg tccataaggc attgctgtga ttccgatatt ccgataaaaa
    40201 tctaaactgt cccccattcc tgtcccgatt gaaacgtttt gaacttctcc tttttcatcg
    40261 atttgttcaa gcaatccttg gatagcacga taagcgactt ctttatattc ttgtggtaaa
    40321 taacgtttat ggaccgcttt caaaataccg taagcaaatc ctgcagttgc agaagattct
    40381 acgtaagaag aaggatcatc caacaacgta tgccataaac cgctttcaga ctgataagtt
    40441 tttaatgcac gcacttgtgc ttcaagtgtt tcgatcaata atttgcgcaa tgcatcttct
    40501 ttcgataatt ctaagatttc aatgatctct ggaatagcaa tcgtcaacca gcagtttcca
    40561 cgagcccaaa atgcttcggc atagttatga tttccttcaa acgtccagcc gtgataccac
    40621 aatcctgttc gtttatccat caagtatttg atatggatca taaactggta acgagcttct
    40681 tctaaatatt ctgggcgatt caacagtttc ccgatttttg ccaaaggaag cactgtcatc
    40741 atcaatgtat cgtcccacaa ctgattctta ttttccggtc catatgtggc atgctgtaac
    40801 ccgtcttcat ttgtccgagg catgtcattc atgacccatt ctgcccattg ttctaaataa
    40861 ggcaaatagc gtgaatcttt cgtgtcttca tacaagtaag ccatagtcaa tagcggtgcc
    40921 attgtattga cgtttttggg cggagcgcct tcttccatac gatcctcaaa ccattcattg
    40981 accacttgat aagcgcgagg attttttgtc atctggtaat ttttataaat accatataga
    41041 ccgacacctt gtggccaatt ccacactgtc cagcttttgt catctacttt cagtccatca
    41101 aagtccaaca aaaattcacc attatcgtct ttgatcgttg tcaggttttc aacgagcagg
    41161 tcaatttttt ctttcactaa ttctttaggt acaaaaatct cttctttaat aatcatcttt
    41221 acgccacctt tttaaacgct ttcattttat atccttaata tagcagtaat accgtccact
    41281 ataaatatcg ctttttgaac aaaaactgtc taaaattgac ctaaatgtta aataacaaaa
    41341 gtaactttca gttacttgga aattaaaaaa agaacttgga gaaacaacgt tttccaagtt
    41401 ctttttcatc tattttctta tcttttttct acgctttctt ttgcttatcc gttgtaagca
    41461 tcaatgatga tctgtttcaa ttcagagatc aatggttctt tcggattagc tgtcgtacat
    41521 tggtcttcgt aagctaattc agccatacgg tctacggttg tatctagtgt ttcttgtgtg
    41581 actccttgag cttttagact catgttgatg ccgacagatt ttcctaattc ataaacagcc
    41641 gttgctaaag cttcgactaa ttcctctgtt gtttcgcctt tcagacctaa gaattttgcg
    41701 atatctgcgt aatctgtatc tgcacggaaa tagtcatatt tagggaacat cgcatgtttt
    41761 tgtggatctt ttgcattata gcggataata tgcggtaaaa gaatcgcatt tgtccgtcca
    41821 tgagggatcc cgtattcccc gccgatttta tgtgcgactg agtgacaaat acctaggaat
    41881 gcgttagcaa acgccatacc agccattgta gaagcgttgt gcattttttc acgtgattcc
    41941 atatcaggtg tttttactga tttttctaaa tagtcaaaga ctaacttgat tgcttgtagg
    42001 ctcaatccac gtgtataatc tgaagccatg actgaaacat aggattcgat tgcatgtgtt
    42061 aacacatcca tcccggtatc tgctgtgaca gatgctggaa ctgacatgac gaattgagga
    42121 tcgacgattg cgacatctgg cgtcaatgca taatctgcta acggatattt cacatgtgtt
    42181 tcactgtcag tgatgaccgc aaatggcgtt acttcagaac cagtccctga tgttgtcggg
    42241 atacatacga attgtgtttt ttctggtttg tcgatcttat atgtccgttt acggatatcc
    42301 aagaattttt gttttgcacc aaagaaagat gtgtctgggt gttcatagaa catccacatt
    42361 cccttagctg cgtccattgc agaaccgcct ccaagagcga ttactgtatc tggcttgaag
    42421 tctgccatca gtttcgttcc tgcgtatacg gtatttgtcg atgggttcgg ttcaacatct
    42481 gagaagactt cgatcttcac atcattttta cgtcgtgcca atacttcacg aactgtatcg
    42541 cagtaaccga attggaccat accagggtca caaacgatca tgacacgttc aacgttttcc
    42601 attttctcta agtacaatag agagttcttt tcaaagaaga tttttggcgg taatttgaac
    42661 cattgcatgt tatttctccg tttcgctaca gttttgacat tgattaagtt tacagcagag
    42721 acgttacgag aaacagagtt cttaccataa gaaccgcatc ccaaagtcaa tgacggaatc
    42781 atttcgttat agatatcacc gatgccgcct tctgcagatg gtgtattcac taaaatacga
    42841 caagctttca ttcgaagacc gaatttgaca tgcaactctt cgttttctga atggataact
    42901 gctgtatgtc ctaatcctcc aagattcaac ataccttcac acaaatcaaa cgcatggtcc
    42961 gtgttgttag ctttgatcat ggcaagaact ggagaaagtt tttctcttga tagcggataa
    43021 tctgggccta cgccttccaa ttcagcaatc agcattttcg ttccttttgg tacactgatt
    43081 cctgccaatt ttgcgatttc catcgcagaa tgtccaacga ttgatggatt gaccgcatat
    43141 tttccttcgt tcatcactgc atcttctaat ttttgcaatt catctggttt tacgatataa
    43201 acttggtgtg cttggaattc tgcttttact gctgcataga tttctttatc cacgatcaca
    43261 gcttgttcag aagcacaaat cattccatta tcaaatgttt tcgaaacgat caaatcgttc
    43321 actgcacgtt taatttttgc tgttttttca atataagctg gtacgttacc tggacctaca
    43381 cctaaagctg gttttcctgt agagtaagca gacttgacca ttccagctcc acctgtcgct
    43441 aagacgatcg cgatacctgg atggttcatt agcatagaag tcgcttcgat cgaaggatgt
    43501 tcgatccatt ggatacaatt ttcaggagct ccggcagcga tagcagcatc acgtaccact
    43561 cgtgctgctt ctgcagaaga tttttgggca cttggatgga aagcaaaaac gattggattt
    43621 cttgttttca acgcgatcat tgatttgaaa atcgttgtgg aagtcggatt cgttgttgga
    43681 gttactccgc aaaccacacc gactggttca gcaatttcaa tcaacccttt ttggacatct
    43741 tcattgatca caccaactgt tttatcatgt ttgatattat gccaaatata ttcggacgca
    43801 tacatatttt tgattgcttt atcttcgtaa acaccgcggc ctgtttcctc tacagccatc
    43861 ttcgctaatg gcatatgttg atccaaagct gccattgcca tttcatgcac gatatggtct
    43921 actttttctt gatcaaagct ttccatttct ttcaatgctg catttgcttt ttctgccaaa
    43981 tcatcaatca ttgcttgtac gtcaattgtc ttcgtttttt ctttttctat tactttagcc
    44041 atcattatcc tcctaatggg tcatggttat ttgttaaata attcacatgt atatcataca
    44101 atatttattt ttctatgtaa acactttttt gtgatttttt tcacagttat ttttaaatat
    44161 aaaattgctt tatttacagg tgtttgtata gaaaaatata taaagttatt tattattatt
    44221 tatatgacac acccgattat tcaatattga gcaatatatc ccatgctctt atctctttct
    44281 tttttgaata aaaaatgagg taggacatct ttctgcccta cctcgtcttt aaataagctt
    44341 tgatacttat ttttcttcct tctcttctgt ctcttccagc gtttctgttg tttcagtttt
    44401 tacttcaact gtctcagctg gttcttctgt tgtttcaaca gtagtcgttg catcatttgt
    44461 tacgacagtc cctggtttga ccgttttgat tgctgcacga tcgtactcaa ggaagatccc
    44521 ttcgcagtct aaaacaactg tccgtttgtc attgtcgatt tctgaaacaa ctccatgtaa
    44581 tccgccgatc gttacgactg aatcacctgg tttcatgcta tctaacaagt tttgacgttc
    44641 ttgctgttgt ttcttttgcg aacgtgacat aaaaaaccac attgctaata gcgcgataaa
    44701 catcacaagc attggtaatg ttcccatttt tttcacctca ctaattctgt atctacaaaa
    44761 aacactttag cagaaaaatg ctgataacac tagtttttta cttaattttt aaaagatttt
    44821 cctttagaag ctttttgcgt tttctttatt gaacccgtat tcttcaaaaa aggcttctct
    44881 aaattcaagc aaattatcat ccatgattgc ttgacgtact tgtttcatta gattcaacaa
    44941 gaagtataaa ttgtggtaag aagtcaaacg aatcccaaat gtttcatcac atttgatcaa
    45001 atggcggata taggcacgtg tatagttttt acatgtataa caatcacatt tctcatcaat
    45061 tggacggaaa tcatgggcat atttcgcatt tttcactact agacggcctt gagaagtcat
    45121 acatgtgcca tttcgagcga ttcgagtagg caagacacag tcaaacatgt ctactccacg
    45181 gataacacca tcgatcaatg aatcagcagc accgacaccc atcaagtaac gtggtttgtt
    45241 ttcggggatc aacggtgtag tgaattctaa tacacgattc atttctgatt taggttcccc
    45301 gacagataac ccgccgattg agtaaccagg gaaatccatc ccgactagat ctttcgcgct
    45361 ttgacgacga agatcttcaa accctgctcc ttggatgatt ccaaataatc cttgacggtc
    45421 tggattagca tgagctttca atcctcgttc tgcccatcga gacgtacgtt ctactgattt
    45481 tttcacgtag tcgtaacttt catcgaatgg tggacattcg tcaaaactca tcatgatatc
    45541 agagcccaat ttattttgga tgttgattgc tttttctggt gataaaaaca tacgcgaacc
    45601 gttcaagtga tttttgaaat gcacgccttc ttcttcgata ttccgcatat cacttaatga
    45661 aaaaacttga aagccgcctg aatctgttaa aatcggttga tcccagttca taaatttatg
    45721 cagtccgcca gcttcttcta ctaagtcttc accagggcgt agccataaat gatatgtatt
    45781 acttaaaata acgccagcac ccatttcttt caactcttct ggggacattg tttttactgt
    45841 agctaatgtt cctactggca tgaacattgg tgtggggaaa gttccgtgtg gcgtgatcaa
    45901 ttcccctaaa cgcgcgccag tatgtttttc tttcttgatt aaacgatagc gaatggcagg
    45961 ttgcgtcatt catttcccta ctttctatat aaaatatctt gacaactccc accatcataa
    46021 tcgtttcaag tgctttttgc aagttccctc ggcttccttc tactttattt aatattcttt
    46081 tttttatcct ttttttatga ataacaaaaa aaagaaaaac attatgacag aaatattttt
    46141 tgatacatgg tatattggtg ttattaaaga aaaggaggga aaaatcatgc aatcttctgc
    46201 agaattaaaa cgccaagcaa aagagagtct aaaaggacgt tggggacaag ctgttttact
    46261 aaatctaatc cctacattga ttggtattgc tactattctt cttattatga ttcctattat
    46321 cttgtttgcc accaccatat atgatggatc agcgagcgtc tcagaagcga caacttcagg
    46381 aggcggtagt tcaggaggcg gtggcggaat tatttccagc atcattagcg ctttgttcat
    46441 gagcggtatt tcttggactt atcttgatat tttacgtgga caaaaagatc agatcgaacc
    46501 attcaaagat gcatttcgtg gattcaaagg tttgtttatc ggcggagtga tcagcttagc
    46561 tgtgctgatc tcgatcttta caacattatg gggtttgcta ttagttattc ctggaatcat
    46621 taaaagctat tcttattctc aaagctattt tatttactac gatatcgtcc aagaaacagg
    46681 acaaacacct aaagtactgg atacgatcac tgcaagtcga aaattgatgg atggttataa
    46741 aggacaactt ttctggttag atctttcatt tatcggctgg catatcttag cattagcaac
    46801 tgctggtatt ggttatctat ggctcagccc atacatttct gcaacaaaag cagcatttta
    46861 tgaacaattg ccaaaagata tttaaaagag agtgtgactt gtgaccgagg gggtggcagg
    46921 agaacaccgt ttatcgagag gcagtaaaag aaacattcag cccattagca aaaaggaggt
    46981 gtgacaacat tcatgtcaca cctccttttt gtatagttcc agtaaaaaga aaatcaactt
    47041 agaaacagtt aatcattcct cttcttctgc ttccggtaat cgatggaact tgatcagttc
    47101 attcaccgcg attggtacga tagataaaat ccctaccaag aaccagtgat tcaaactgat
    47161 gtgtactagg ccgaatagtt cttgcgtaaa tggcagcaaa gcaacagccg ttgtaatagc
    47221 taatgccagt aacgccattt ctaccaaagc tttattggtc gctaaattga ctttgaagat
    47281 cgattggctg ctgcgtacat tgaacacatg cagaatcgat gaataagcta agatcaagaa
    47341 tgcaacagtt tgaccgacat gctgacttgc gtctacccat gggctgatag tatcgacata
    47401 actacctaaa taataaccaa acaaggttac gatggtgaag acccctgcat ttatggcaat
    47461 tttttgcaat aaacctcgag caaagatccc ttcatttttc ggaatgggtg gctgatccat
    47521 gatgccgtgt tccgctggct ctcttcctaa agcaaatcct ggaagtccat cagcaactac
    47581 attgacaaac agtagttgca cagctgtaaa tggtgctccc catcctaaca gcatcgcaat
    47641 caaaacaata aagatctccg aaatattaca gcttagcaaa aagttgatag ctttacgaat
    47701 attctgataa accgaacgtc cttgactgac agcgtctacg atcgtcgcaa agttgtcatc
    47761 cgtcaaaatc atatctgcgg cactttgcgc cacatctgtt cctgtgatcc ccatggcaca
    47821 cccaacgtta cttgctttca acgctggtgc atcattcaca ccatccccag tcatcgctac
    47881 gactgcaccc gtacgttgcc aagatttgac gatccggatc ttgtcttctg gcgttacccg
    47941 agcatagaca gagagagctt tgacacgcgc atctaattct tcgtctgata attgatgcag
    48001 ttctgatcct gaaagtgctt ctgacggatc attcaagata cctaattctt tcgctatggc
    48061 actggcagtc accacatgat ctccagtgat catgactgtt ttgatgccag cctttttcgc
    48121 tcgcttgatt gctcctttac tttctggacg tggtggatcg atcattccga tcagaccaat
    48181 caaacgtaag tctttttcca gtgcttcaga agaaatatct tgcggttctt cgtcataagt
    48241 agcataacca acagcaatca ctctcagtgc ccgtttacca aagcgatcat taacgatcgc
    48301 cgcttgttct acatcgcctg aactaaagcg cggagcaaga acatcgaatg ctcctttggt
    48361 gattgagatg tatttttcgc ccatttggtg aactgttgtc atcatttttc gttcagaatc
    48421 aaaaggaagc tcgtttactc gtggatattt ttcttctaat tctgcctttg tatgataatt
    48481 ctcttcaaca gcccttacga tggctacttc tgttggatta cctttgataa caaggtcgtc
    48541 atcttcttgc tcgaccgtca catctgtaca tagtgcagcc attttcaata tttccatcgc
    48601 gctgttcgtc attgaatctt cgatattcgt tacttcatct tctttgctcc atacccggcg
    48661 gacgcgcatt tcattttgtg tcagcgttcc tgttttgtct gagcagataa cattagcggt
    48721 tcctagcgtt tcaactgctg gcaactgtcg gatgatcgca tgtttcctcg ccatcttctg
    48781 cacaccgtat gcaagtgtca acgtaacaat aacagtcaag gtttccggta cagctgcaac
    48841 agccaaggaa atcgaagtca tgaacatctc aaggagtggt tctccttgca gttcaccaat
    48901 cacaaatact aaagccgcag ccgctaaagc gatcatactg attcgtttgc ctagctgatt
    48961 caatcggacc tgtaaaggtg ttttttgcat agtattttcg ttcaaaagat ccgcgatctt
    49021 acccatttct gtagccatgc caatggcagt gacgatcgct ttcccacgac ctgcagcaac
    49081 cgtacatcct ttaaatacca tattaagttg gtcacctaat gactcatctt cttcagcaat
    49141 aaatgctgca tctttttcaa ctgcttcact ttctccagtc aacgccgatt cttctacacg
    49201 taattgtgat gcttcgatca aacgggcatc ggcagaaata gcatcaccgg actctaaaac
    49261 aagaatatca cccactacca gttgctctga ctcaacagtg gtcactttgc cgtctcgtat
    49321 gacagttgcc gtttgtttat tcatatcttg caaggattcc agtgcttttt ctgcgtttcc
    49381 ttcttggaca atcgccaata ccgagttgat cacaacgata gcgatgatca gcagtccttc
    49441 aaataaatcc ccatgttctg tagcaaatgc ggtataaaag gaaatcaccg ctgctacaag
    49501 aaggatgatc gttgtaaaat cggacaagct tcgaaagaat tttttgatca tcgattcttt
    49561 cggcgcctca tcgaatttat tcaatccctg cttttttcgc cgttcatcca cttcttgtga
    49621 agacaaccca gtatctggat ctgcttctgt taccttcttt acttcttcta ttgtctgctt
    49681 gtattcttcc atcctattcc tcctttaaaa tcttcgtaca aaaaaaggta cttattttac
    49741 tataacatcc tttttttatt tacttcaaat aaagggctta tcgattattt gttaagaaag
    49801 cgtaaaattt aaagtgctta tatttgcaaa cgctaccaaa ggatgctatt atatagatgt
    49861 aaggaaggag gataccatca aatagacaga agaatttctc gatagaacag tgtaagcaaa
    49921 caaagttgtt agaagtacag gtttcaccca gacatgcgtg tagagtacaa acctataaat
    49981 agtgaatgcg tatggatgtt tggatcacga agtatccgaa acaagaagta atgcgatacg
    50041 taacaattga ataacgtaaa cgtctgaaaa ttgaatagga acaagagatg tttcaaatgt
    50101 tgaagatgta acgaaaacaa aatttttgtt taacatgaag aaattcaaca ccgtgctttg
    50161 catgtatgat ggaaagttac aatcatttct gtttatttga atccttccga ggtacaagaa
    50221 agccgagctt atcgagagct cggctttttc tttgtcataa aatctttgta aagctttttt
    50281 gttattcaaa actagcggct tttcataacc ttatttcacg aacatcgcat ctccaaaact
    50341 aaagaaacga tagcgctctt caatcgcatg ctggtaagca gataaagtca attctcttcc
    50401 tgcaaaggca ctaactaaca tgactaaagt cgattttggc aaatggaaat tagttgagaa
    50461 agcttctacc actttgaatt catagccagg cgtaatgaaa atatcagtcc atccgctgtc
    50521 tgctttgatt tctccattaa atttcgttcc aatcgtttct aatgttcgaa ttgaagttgt
    50581 tccgacagcc acgattttcc cgccattttt acgtacttgg ttcaatcgct cagccgcttc
    50641 ttccgtcaaa cggtagaatt cactatgcat atggtgttct tcaattttat ctacgctgac
    50701 aggtcggaat gtacctaacc ctacatgtag tgtcagatag actaattcaa caccctttgc
    50761 ttcgatctca tcaagtaatt ctttcgtaaa atgcaatcca gctgttggcg ctgcagcaga
    50821 accattttct ttcgcataga cagtttgata gcgatctggg tcttccagac gttctttgat
    50881 atatggaggc aatggcattt ctcccaatga ttcaagaatc tctagaaaaa ttccttcata
    50941 ctcaaagtca atgatccgtc cgccgtgttc caattcttct ttcactactg cttgcaatct
    51001 gccatcacca aaagagattc ttgtcccaac tttggcacgt ttcgcaggtt tgatcaatgt
    51061 ctcccacgta tctccttgtg tattcgttag aagaaggact tctaaatgcg caccagtatc
    51121 tggtttttct ccatataaac gagcaggcag aactcgtgta ttattcataa ctagcgcatc
    51181 accaggctgt aactcttcaa tgatttcatg gaaatgttta tcttccatct ctccagtttt
    51241 ccgatccaaa acaagtaaac gagaatgatc gcggtctttt aatggtgttt gtgcgattaa
    51301 ttcttccggc aagtcaaaat caaaatcttc tgttgttaac atatcgtcac tcactttcta
    51361 tcatgtgctt catcattcta tcatgttttt cgttctgttg gcaaaatcag cactttttca
    51421 cttctatttt ttgttttcct aaataaaaaa actaccctat ttgtattttt tcattgtttt
    51481 aggcatacta gtaatagata gttcttcatt gaaaatagaa aaagaggtgg caccatgatt
    51541 gaatttcaaa atgtgtcaaa aatttataaa ggtggaaaag tcgctgtaga ggacgtcaat
    51601 ctttcatttg aaaagggtga gttcatttgt tttatcggta cgagcggaag cggaaaaacg
    51661 acgacgatgc ggatgatcaa ccgaatgact gatccaacac aagggaaaat tttgattgat
    51721 ggaaaatcca tccaagaaat tgatccagtg gaattgcgac gtcagatcgg ctatgttatc
    51781 caaagtattg gattgatgcc tcacatgacg atccgtgaaa atatcactct tgtccaaaaa
    51841 ttgttgaaag tcagtcaaga agaacggaat aaaacagctg aaaaaatgat tgatcttgtg
    51901 gaattgcccc gtgagatgtt agatcgctac ccacatgaat tatctggtgg tcagcagcag
    51961 cgtattggag tcgttcgtgc ccttgcagcg aatcaagata tcatcttgat ggacgagcca
    52021 ttcggtgcgc ttgatccaat cactcgtgat tccttgcaag accttgtcaa agatttacaa
    52081 gagcgtttgg gaaaaacgat cgtatttgta acccatgaca tggatgaagc gattaaacta
    52141 gcaagccgta tcgccatcat gagtgaaggc cgtgtgatcc aatttgatac accagaaaat
    52201 attttacgtc atcctgcaaa cgatttcgta gaagagttga ttggagaaga tcgcctacta
    52261 caagccaagc caaatgcgac aagagtcggc gaagttatgc taaatacagc aatcacgatt
    52321 acaccggaaa aatcattaca agaagcaatc aaactgatga gggaaaaacg tgtagatacg
    52381 ttgttagtta ccgataattc gaatgtatta aaaggattta tcgatgtaga aacgttgaat
    52441 aaaaaacgag gaaaagtatc cagtgtcggc gacattttga ataaacatgt tttttacgta
    52501 aaagaatccg cctatcttcg tgataccttg caacgcattt taaaacgcgg gctgaaatac
    52561 gtgccggtcg ttgatgaaca gaacaaagtc gtaggtatcc tgactcgtgc atcattagtg
    52621 gatatcgtct acgatgtgat ttggggagaa gatcccgcaa ctactgatgt tgcagagtca
    52681 gctactcctg aagaatctaa ggaggtctga cctatgcagc agttttttca tcagcacggt
    52741 tcagaaattc tctcaaaagg ttttgaacat ctttatattt caggacttgc tttgatcatt
    52801 ggtatcatca ttgctgtacc gcttggtgtc ttactgacac gttttccaaa agctgccacg
    52861 attgtgattg gcttaaccag tgccttgcag acaatccctt ctcttgcttt attggcattg
    52921 atgatcccgc tatttggcgt aggtaaatta cctgcgatta tcgcactctt tatttattca
    52981 ttattgccga ttttacgtaa tacgtacatt gggatgaaaa atgtcgattg gaattatcgg
    53041 gatgtggcaa aaggcatggg gatgactgag ttccaatcca ttttttccgt tgaattgccc
    53101 attgctatgc caacgatcat ggctggtatt cgtttagctg ccgtttacgt gattgcatgg
    53161 gctacacttg cctcttatat cggcgctggt ggtttaggcg atttgatttt tagtggactg
    53221 aataattacc aaccagatct cattttggca ggtacgatcc ctgtaacaat tttagcacta
    53281 ttggctgatt ggcttctagg tctcttggaa caccggctga caccgatcgc acttagagag
    53341 gagaatgaag aatgaaacgt atactaaaaa tgaccatggt tcttttctct cttcttatac
    53401 ttgcgagttg ttccttccct ggtcttgcca gcaatacaga tgaagacacc atttcgatca
    53461 caggtggaat cacttcagaa gcacagatct tagcaagtct agttgccgga atggttgaac
    53521 attatacaga taaaaatacc gcaatcatca acaatctggc tactacaact atcaaccatc
    53581 aagcgatgat gaacggagat gcttcaattt cagcggctcg ctacacagga acagatttaa
    53641 cgactacatt gaaccttcct cctgaaaaag atccgaaaaa agcgtttgct accgtgaaag
    53701 atgaatttga gaaaagatac ggtcaaacgt ggttcccgtc ctatagtttt gaaaatacgt
    53761 atgtctttct tgttcgaaaa gacaccgcac aaaaatacca tctatctaaa gtcagcgatc
    53821 tgaaaaatgt agcggatgaa ttagtagctg gtgtagatac ttcttggatc aatcgtaaag
    53881 gagacggtta tgacggcttc caagaaactt atggcttctc cttcaattcg atattaccta
    53941 tgcagattgg acttgtttat gacgcagtcg aagcaggaaa aatggatatt gttcttggct
    54001 actctacgga tggacggatc gccagttatg atctagtcat gttggaagat gatcgtcaat
    54061 tcttcccacc atatgatgct gctccagttg tagacaacaa gatattagct gatacgcctc
    54121 atttaaaaga agccttaaat aagttaggtc ataccatcag tacggaaaaa atgcaggaat
    54181 tgaactacga agcagataat aatctagtgg aaccatcagt agtagcacaa cgtttcttac
    54241 aagaaaacca ctattttgaa gggaagtgaa gcaattggat aaaatgaatg tctttcaaca
    54301 atttttctat tatttccagg aaaatggctc ctatatcttt gcacaattta tccgtcactt
    54361 cctgatttct atctatggtg tcctctttgc agcagttgtc gggattccgg ttgggatcat
    54421 gatttctagg agacgtaaat tagcaaactg ggtgattcgt ttggcgaata tcatccagac
    54481 gatcccttct ctagccatga tctccatttt aatcattgga ttaggcctgg gagtcaatgt
    54541 cgtgattgtt actgtatttt tgtattccct cttaccgatc atcaagaata cgtataccgg
    54601 gatgatccaa gtagacaaaa acatccttga tgtcggcaaa ggcatgggga tgactgctag
    54661 acaacgacta ttcatggtag agttaccact ctctgtttct gttatcatgg caggcataag
    54721 aaacgcgtta gttgttgcca tcgggataac cgcgatcggt gcattcgtcg gtgctggtgg
    54781 tcttggagat atcattatcc gaggaaccaa tgcaacagag ggcacatcga ttattttagc
    54841 aggtgcattg ccaactgcat taatggcgat catcacggac tggcttttag gtattttgga
    54901 aagacggcta gatccagcca gccgtacatc acgctgatgt tattgtaaaa aacaaaagct
    54961 tctgcgacca tttgttggtc gcaaaggctt ttttagttct gtcattttta aggcaataat
    55021 ccactctgat tcttccctcc ttatgggcaa agagttgctt ttcttagcta tttatccatt
    55081 ccgtatactc caacttcata ctgccaacgg gttcatatct gcatccaccg actaagtttt
    55141 tttcttatcc gctaaggcat tttgccaatc cattttccca tcactcgtca tggaattcat
    55201 accacatgat ctctaaatac tcgtctgctt gttctttgaa ttgggcatca attcttacat
    55261 cctttggcgt ggctttcatt taagcctttt ccatcagtcc tcgattgttc gatgccttca
    55321 gctgcatcat caaaactggt gactgccgta tcggtaactt cgatcatctt ttatacaatc
    55381 gggaacttgc catcctcatc cttggctaaa aacatatcta gccattccag cttctcgcca
    55441 tgggaggttt gcggttccta aaaccggtac acgattctta tggactgcat ccgtcgcaac
    55501 tagacttggc gatacgatga tccttcacca gaagagcacc cccgtaaacc aattgatcga
    55561 tatattgcca ataagaaaag acattggcgt aaaagatatc gatccctcgt gatgcattgc
    55621 cgttgatact gctattcatg gccgaaagcg ccacgacttt aacttcttcc gtttgagtga
    55681 cattcatgtt cggcaatgtc gctttggata cccgctctgc taaaggaacg acactggtat
    55741 tgtatttcgt atctgtatct tttccaaaag accatgccaa cgaatcctct gggaaccaat
    55801 aagacgactc cggttgattg tccattgctt ttttcaacat acttttggct gtttctcgat
    55861 aaacgacatt tccaattgtc ttcgcctcac tttggcgata atcgatggtc gttgccactg
    55921 ccaacactaa caacgatgct ccaattttac tgattttcct tgtcacactt cttcctcctt
    55981 gttttacata aacccgtcaa cattccattc ctaaactcaa acaatgaccc ttcaaaggtg
    56041 gagatatagg aacaaattaa agaaatcatg caataaatcc aagaaggttg gttttagaac
    56101 aaaaaaagag tctccttttt ggggagactc tttgttaact atctaaaaag gttggctctt
    56161 ctcacttcac tcataatgtg tccaggcaga ataaatttct acaactttat tttcctcatc
    56221 aactttgtaa accactcgat gctgtctatt cagcctgcgt gagtatctgc cttcatgtgt
    56281 aggtctcagc ttttcaaaag actgcgtggg catatatgga tcttccttca atgtctgaat
    56341 cacttcttca aattgtttct ttaaattcgt ttgcttgatt tttcttaaat ccactttcgc
    56401 agagtttttg attgcgactg tatagttact catcaaagag cttcccaatc aatatcatcg
    56461 atattcgtaa agctactgtc gtctttttcg cggtctcgta ctttatctaa agtacctgtt
    56521 tgctcaagaa aaagggtttc ttgaatcgct ctccagtctt ccagcccaat caatacagca
    56581 ttgtttccac tacgatcact aataatctcg atttcagtat gattttcatt tacctctttc
    56641 aataactgat aaaaattttt acgagcagtg ctaggattca tcgttgtatt agccattgtc
    56701 tctcctcctt tttctgatat aattatagcg tacttgatta agtacgtcaa aaaaatacaa
    56761 taaagcactt aaattcagca aacttttcct cttttttaca tagagaaaaa gacccctttt
    56821 tagggaggat ctttgtccac gctcacttct tactccttta cgactagcgg tagccaaacg
    56881 taaagtaatt ggtaacaacg tatcatcttt agcaaaggtc gaatccaaag cctgtgagtc
    56941 tatgcaacaa caccaataca cgaaggttcc tcgttgcagt gtgacttgat tgatatcttg
    57001 aataacctga ggatacgcac gaaagatttg taacggttat tcaaaactga ttttggccgt
    57061 caagtcttct actgcctcaa aaatgattgc ctctttcgtc tcctgtcatt catgttcact
    57121 atcgatttga tacttgctta gaccgttggg tttgtgaatc accaattaaa aatggcactg
    57181 agttatggta acaaaaaatg gtcacttgac gaggctgaga ttcctactta tgaagacaca
    57241 tggcacttaa gagtcgaggt aaaggaagaa gctgaaaata taggaggctg tacattattt
    57301 ggcaaaggat tcggaaatta tgatcaagac atcaaaatca aaatgtttta cagctaaata
    57361 ggaagaataa taacatttca tacgctgttc ccatctttaa tggcttatag agggcacctt
    57421 tagctgagaa taagacaaaa cagaccctct agcttcaatt aagagctaga gggtctgttt
    57481 ttgattttaa aacttggttt atttcttcaa atggtagcta taggtgctga caacgatatt
    57541 ttcacgccaa gacaatcgca atcttaaccg caaacttgtt tggttatgga gaatattctg
    57601 ccagcgtctg tttggtacaa attgaggaat caacacagta gttgtatagt tttgtttcgc
    57661 tgcattttta cttacgatat ctacataacg gataattgga ttttcaatcg agcgataaga
    57721 agagtggacg attgaaaaac ggacatctgg gaaatgcttt ttaaattctg cttcgatttc
    57781 tttttctttt tcgacatctt cgtctagcga aacatgcatc gcaacgacat aatcaccgat
    57841 cgaacgtgcg taattcaacg caccgatatt tacccgtgtc acattcccga ctaatacaag
    57901 aacggtattc ccgtcataat catgtagttt tgcatcattt tctaaacgaa gctgttctgc
    57961 tactttttta taatgatcat ggatcttata aaaaatgaac ataacgattg gcataatgat
    58021 gaagaaaggc caaatgtccc ctaaccgata gacaaacaaa atcgcaatga ttgcatatga
    58081 gatgaacgca cccgtaatat tggcaatcga tttgcttaac catctttttc cttctttttt
    58141 ccatttgacg accatccctg tttgagataa agcaaatgga atgaacacgc cgatagagta
    58201 taacggaatc aagcgttctg ttgagccatg gaaaataaac agcaatacga tcgaacctag
    58261 cgctagtgtg ataatcccat tggaatagcc tagtcgatcc ccacgatctt gatacatgtg
    58321 aggcatgaat ttatcttttg ccagattgta tgcaagaact ggaaaagcag aaaaaccggt
    58381 gttagcagca actgctaaaa tcagcgctgt agcaaattga aggacgtaat acaaaatacc
    58441 atgtccaaag acagctttac caatttgaga caaaacagtg acttcttttt caggaacgat
    58501 cccataccaa tagttgataa atgtgatccc cacgaagaag aaacctaaga tcaatgccat
    58561 catcgtcaat gtagcagcgg cattttttgc tcttggcttc ttaaagaatg gtacagcatt
    58621 actaatcgcc tccaccccag ttaaagagga agaaccagaa gaaaatgctc gtaaaatcaa
    58681 agcgatagaa acacccggca cagccgctcc tggaagtgca gtagcttgca atggcacagc
    58741 acctgtcacg atattatata aaccaacaac gatcagtaac gagatcacaa ggataaatgt
    58801 gtacaccgga aataatagga acgatgcaga ttccctcagc ccacgaagat tcagcatcat
    58861 cagtagcaaa acgattgtca cagaaatagc gacttgatga ccgtagagtg ctggcaccgc
    58921 tgatgtgatc gcttcagcac ctgctgagac agatactgct actgtcaaca tgtagtcgat
    58981 caataaagag ccaccggaaa tcaagccagc attctttcca agattctcac tgctgacgac
    59041 atatgctccc ccgccatgag gataagcatg gatgatttga cgatatgata gcgttaatga
    59101 aatcaataaa ataataacaa aagcggcaat gggtagcgaa taccagatgg ctgcagcaga
    59161 caaagcgact aaaacgacaa cgatttgttc cgtaccatat gcaatagatg ataacgcatc
    59221 agacgacaat aatgccaaag cagcaaatcg ggttaatttg tgctcatcat tttcagcaga
    59281 ttttaaaggc ttacctacta acaacctttt taagtaatcc aatttctaaa ctcctttaca
    59341 cacaatttta cttcaagttt tatagtcgaa aatttatagt aaacaagatg ttatagtacg
    59401 ctcactgacc ttaaaagtca ataaacttta agaaaataat tggaaaaaaa cagaaaaata
    59461 tcaagcgctt tttcaaacgc tttaatacag caaaaatcta acattttttt atgggctttt
    59521 tctttgaatt ctataataaa aggatagaac ttgacttaga aaatcaagtt ctatcctttt
    59581 tgatatctta acttttggaa gagagatgta aggctgcttt ctacccatca ttcttactac
    59641 tcgaagcata gcgcagttgt cacaacctct tgataaacgg tgtttaaaag cttgcatctg
    59701 cggtaataag cccaaccaaa ttaaaaacat aagaagctgt ttttatttgg tcgttcttat
    59761 tacttgatgc agagcagctt ttttacaacc tcttggtaca cggtgttcaa tcagctgacc
    59821 ctcggtatta gctcaaaaaa acggcaaaat atgaggaact atttttccat ttttttctct
    59881 aatactcagg tcaaaacact gatttcacaa cctctttttt taatgaaaaa tatggctctc
    59941 atgcgccgct tctttgaatt tcgtcatttt ttcttcgatg aacggataga ttgccgttcc
    60001 tacgattcca aagacaacaa acaaaccgat catgatccag attgctttcg tagcatttgg
    60061 ccaataaatt cctcctgcag attcccgtaa caagtttacc gcatgagtaa atggcaagaa
    60121 cggattgatc atttggaaga atttccctga gacttggatc ggatagttcc cgcctccgcc
    60181 agagatcgac agtactaaga tgataatagc gatcccttta ccgacattat cgaataatgc
    60241 agccaagaca tagacgatca tcatgaacgc taaggcgatc aagacagcaa atgacacgct
    60301 gtagaccgga ttttggacat ctactcctag taagaaaata ttccctaatg taacgatcaa
    60361 gctttgcgca atcgccattg tcaaaaatgt cagcatacga gcaacgaatt gttctcgttt
    60421 cgtaaaattg tttcggtctt tctttcctaa atagtattct gtcgtagcaa cacttgaaag
    60481 aagaacagcg ccgacccaca gacatagtgc agtataaaac ggggtgctag ctgaaccgtt
    60541 atttgcgatt ggataaagcg cattggtttg tagctcaaca ggttgtgtaa agaagtcact
    60601 ttcttttgtt gcgtctagtt tcaataattt gatgacttcg cctagatcga cttcttgttc
    60661 gccttttcgg atcgcgtctg ctgctttttg gataccagct ttgatatttg gccagtcatt
    60721 gttgatcaag tccgcagcag cgttcacagc tgtttcgact tctggcattt tttcatttac
    60781 tgttgtcaat gtaccggtga tttcattttt tagtgctggc caatcatttt ggataaaatc
    60841 agcggccaat cctaattttt gctgaatgat cggtaattca ttgttgtata ggtctgcccc
    60901 ttcattgatg ccattgacga tggtatccat atttccattc agcattgtat tggcatcatg
    60961 gatttcttgt ccaattgcag gcatttcttt ttgatatttt tctaaaattg ccactgcatt
    61021 cgttacagtt gctttcgttg agctgagaag cgaatcaaag tcgatctggt ccgctttgct
    61081 cagtgcgcct tgtgcagtcc caatcgtatc gatgacttgg tctagtagag aagtgacagt
    61141 ggaactgatt tgacctgtat tgataccagc aatgatgcca ttgatattat taacaacggc
    61201 atcaatttga tctagcaatt catcaatagc cttcgtgtct tcattttgaa cagctgtgtt
    61261 caaagcagat aggcggtttt gcagattgct tagcaagggt tttaattgat ttagctgatc
    61321 aataattggc tgtaatttcg tatttccagc acttgtttgc aatttagtca ggaactcgac
    61381 cagtttatcg attgcatttt gttgttgaga tattccgtca ataaagccgt tcaatacatt
    61441 gctgatgttt ttcttttcat catcagtcag cttaccatct tcaatagctg ttcttacagt
    61501 atctattaac gaacctgtcg ttgttgccac ttgtccaatt gacttcaatg taacatctac
    61561 actgtttgtg atgcttggta tcgcatcttt cagctgagag gcacctgatt ttgtttggtt
    61621 tgctagatca cttgcctgat tttctaaatt tttcacatct ggcaagatat cttgtacttg
    61681 ttggatgatc gtcaagcctt gttttgcttc atcgattcct tggttcattg tctcttggat
    61741 cgaagcaaaa tcgccgtcga tctctgctag ttgcttaccg gcattttgga tctctgggat
    61801 tttttcttgc aaatcaagga tgatttttgc ttgatctttc aactcaggca ttttgtcatt
    61861 caatgcaacg actttttcac ccatctcatc tactttaggg atgtaatcca cgaattcatt
    61921 tgctttattc agtttttcct tgatttcagg tagttgactt tgtaattcga ggacttgttt
    61981 tgtgtagccg tcgatcgtgt ccaaattttc atctgttgat aaaatcatat ctttaacttt
    62041 attgatactt actaggttcg tatcgatgtc gtaacctatc tcattgaata ctttcaataa
    62101 agtcgaactg gctgttttga taaattcatt tgtgatttgc gattggatcg aacttgctcc
    62161 tttatcggtg attttcggtg caatcgcatt gattttttca tttaccgtat attcgatttt
    62221 tggtttcttg atatcaccac tagtaaaact cagcagatct tctgagaaat cctttggcaa
    62281 gtaaatacct gcgtaatact ttccggaacg gactccgtct tctaattgtt cttttgaatc
    62341 aacgaattgc catcctaatt gtttattttt atgaagcgat tcgatgactt gctccccaat
    62401 ggccacttct ttaccttgaa actctgctgg cttgtctgca ctgtaaacag caattggcag
    62461 ctctccagta tttccatatg gatcccataa tgctttgatg ttaaaccacg catatagcga
    62521 agggatgatc atgatcgcga tgatcagaag tgttgcaatc gggtttttga aaatccgttt
    62581 ccagtcaagc aaatataatc gaagcgtatt tttgattgac tgcatagttc tcccccttct
    62641 tcttttttca gctgaattac tttaccatgt atttcatact tttttcaatc ggcttttttc
    62701 aaaaaagtcg aatttttgga catatcacgg caattgtctc attgtaatct cttacatatt
    62761 gagaaataat taaggattac agcctttact ttatcatgaa ataaaaggga aagataattt
    62821 tatgccaaag tttttatcta ttatacgtat acgcaaaaaa gctaaaacat tttttgtctt
    62881 tgcccctaca aaaatgtttc agcttttttc gttttttatt cctgtatttc ttatttttcg
    62941 aatgacagga tgattttccc agcaggagga tgtccttcaa ctagctgatg tgcttggatg
    63001 acatgcttaa gtgaagcaga cagattcatt gaaataaaaa catgaaaggc tcctttttgg
    63061 taggctttga ttatgccagc aaaggcttct gcatctagat attcctttct tggaacaaac
    63121 gattcataaa agccttcctt tttttgccgc aaatctagat ctgggaggtc atttaatgca
    63181 acatacctgc cgcctggttt catgatctgg atgccggttt ctcctttgat acttcctttc
    63241 gtcgcatcga ttacaaggtc tgcctgatca gcaaattgca gacctggatt tgttttatca
    63301 taagcagcaa atgctgaagc tcctaatttt tttacctttt cctcattttt actggatgca
    63361 ctggttaaga ttcggattcc cttttcatgg agaagctgga tcagacttga cccgaccgca
    63421 cctgatgctc ctagtatcat tacagtatct gtcggctgga tttccgtcaa atggttgatt
    63481 agattataag ccgtaattcc tggcgtgacc attccggctg cttcttccca actcatttta
    63541 tctggaattt ttgctacttt tgctgatggc aacacgactt cttctccgta agtcccgccg
    63601 actgcatgga cagctactcg atcacctaca tgaacagttg tgacatctga accaatctct
    63661 gtcacaatac cagcgccatc attacctggt acataaggga atttcaatgt tcgtatctct
    63721 ttcatttctc ctaaacgcaa ggcaacatca taaggattca cactgaatgc ttttatttct
    63781 acacgaacat gtccagaacc gacttctctg ggatgagcat cgatttcttc aaaaacatct
    63841 tgtgcttctc cgtaaccgtt aattgcaaat cttcgcatgg tcaccatctc cctttttctt
    63901 taagtttacg tttatgcctt tattttgaca aaaaaaatgt cttttcgttt tggcgcatga
    63961 ttcaaaacaa aatagttgtc ttttttcgcg taacgtgtta aattatttat ctaaaagcgt
    64021 aaagattacg atttacgcta ataaaaaata attggaggaa tttgttgatg gctaaaaaat
    64081 caaagattgc caaagcaaaa aaacagcaag aaacgattga acgctatgct gctttacgcc
    64141 aggaattaaa agcgcaaaaa gattacgaag gcttgcgtaa acttccttta gatgctcgtc
    64201 cagaacgatt gaaaaatcgt gatttaatcg atggacgccc tcgcggatac atgcgtaaat
    64261 tcgggatgtc ccgtataaaa ttccgtgaat tagcacataa aggtttgatt ccaggagtaa
    64321 aaaaagccag ctggtaatcc aagtctggct gtaatgtaaa ggaggagggc gcatggacca
    64381 ctccttggat catcaaaaaa gatacgttcg cttcttctag cagaaatgct ggtactagaa
    64441 gcagacgtat ctttttttac gcacagctgg tcctttttta tatgtaaagg ctgcatggtt
    64501 acttcgctat atttatttag taacaggagt cagtgcttcg atacccacac taattttcaa
    64561 tgctcggtca acttctgcca taatgggtcg atccaaatgg cagacctttt ctttcaatct
    64621 tgatttatcg atcgttctga tctgctccaa caggataacg gagtctcttt ctattcctgt
    64681 tccagtagct ttgatcccaa tgtgagtcgg aagcttaggt ttagccattt ttgccgttat
    64741 ggccgcaaca atgatcgtcg ggctaaaatg gttacctaga ttattttgaa taaccaaaac
    64801 tgggcgtgtt ccgccttgct ccgatcccac gactggagaa agatcagcaa aataaatatc
    64861 tcctcttttt accataggat cctccttatt cttgatattc tcttggtatc cgctgtccta
    64921 atccgcaagc cacttcatag tggatcgtac ctaattgatc tgctatatcc tgcatagtga
    64981 tttctttgtc tgcatttttg ccgataagcg tcacttttgt tccgacagga aattcttgag
    65041 gcaatcggat catcagttga tccatacata cacgcccaat cgtttcacag tagttccctt
    65101 ctaccaatag agaaaaaccc tgcatctttc gtggccagcc atctgcataa ccgatcggta
    65161 tcgttccgat ccactctgct tcaggagtga tatatgtttc tccatagccg attccttcac
    65221 ctgctgggag ttttttgact tgaatcaatt cagaaaccag ctcaagtgct ggctgcaatg
    65281 gataaacttc cggtagtgcg tgcccagagg gattaagtcc gtacattgct actccataac
    65341 gaatcatatt gccgattgtt tcatcatgcc ataaagccgt tgcactattg ctgacatgta
    65401 catatcgagg aagttcggga agttttttca gcacttctat aaagcgttct ttttgcagat
    65461 tccaatatgt atcatctgcc tgatctgctg tagaaaaatg ggtaaataaa ccttcccatt
    65521 ctaatacacg actttctttg atgaatgcag ctgcctcttt tacttcttca ggtgtacaaa
    65581 atccgatacg acccatccca gtgtctgctt ttagatgaat cgaaagaggc gtctctagct
    65641 tacttttctc taaaacagca gctgctgctt gcaaccattc ccgtgtacct gcagttactg
    65701 ataaatcatg agcaacagct acagtcagtg cgtcgtaagg aaccatattc aagataagga
    65761 tgggctgagt aaatccagct tctctcaact cgactccttc atctaaattt gaaacacaaa
    65821 agcccgaagc tccacctgca actgctgcct cagctgtttc aatagctcca tgaccgtatc
    65881 cgttcgcttt tactactgca aacaattctt ttccttgcgg aagtcttgca acttcatttg
    65941 ctacattttc agttatagct tttttatgta tcactgcttt cgttgggcgg tgccaagcga
    66001 caaccatcgt ttttccttct ttctagtctt ccaaaataat ttgtgcaaaa gctgtttcat
    66061 ttgtatgagt aatactgacc catacattgc cttcatgagg tgaacgcgtc acaacaggct
    66121 gaccattttc attttttaaa atctcgacat cttgaaaggt aacttttccg atcccagttc
    66181 cccaagcttt agagaaagcc tctttgcaag cgtaacgccc gcctaaaaat tctacttggc
    66241 gatgaaaagg caaggactgg aatagtttca tttcatcaga ggtcaagatt cgtgcaatga
    66301 attttggttt ttcttcgatc agccgagtga tcctaggaag ttcgactgca tcgatcccaa
    66361 ttccttttat catatgcttt tctcttttca ataaatttag aacactctca ttctaccaaa
    66421 ttataaccat tttgccacaa ataagtccac aaataacaaa aatgaaagtt tctcttaaaa
    66481 aagagaaact ttcattttat gtttaatcgt tatttgaacg gattacaaat ccgcgttttt
    66541 tatcattgtg acgtttaccg ccatcttttt ggctgttatt atttttgcta taaccgcctt
    66601 ttgatttgtt tccacgataa ttaccgccgt cacgacgatt acggttgttt ccgccaccac
    66661 gtttgccatt tttattgtat ccttttttct gcattggcaa tgggcgttct ggtgtgatct
    66721 tcactggcac tgcatcagct ggatcttttg ctgtcgtttt tagcaaaagt gcaactaaat
    66781 cttgtgcaga atattcttct aataatttat ctgctgtttg caggtattta tctagaccat
    66841 tttctgcaag ttttgtttcg atttgttcaa ctgcagcacc taattgacct ttgaatgctt
    66901 ctttttcggt tggtggacgt aaagtcgtca tccgtttttt cgtcaagttt tcaatcacat
    66961 gcaagtagtc catttcattt ggtgtaacga aagtcacaga cataccgcct tttccggcac
    67021 ggcctgtacg tccgatacgg tgaacgtagc tttctggatc ttgagggata tcatagttgt
    67081 acacatgagt gacacctgaa atatctaatc cacgtgcagc aacgtctgtc gctacaagga
    67141 tatctaaatg accgctctta aatgaacgca atacgctcat tcgtttttgt tgagacaaat
    67201 cgccatggat tccttctgca cggtaaccgc gtgcttctaa tccgcgtgcc aattcgtcta
    67261 cacggcgttt tgtacgtccg aagacgattg ttaattcagg tgtttgaaca tcaaacaagc
    67321 gagtcatgat atcgaatttt tcgtattctt ttgcgcggac atagtattga tcgatcaagt
    67381 cagctgtcat ttctttcgct ttgatcttca catgatgtgg atttttcatg aatttaacgc
    67441 caatattctt gatagctggc ggcatcgttg ctgagaaaag taatgtttgt ctttgatcag
    67501 gaacttgtga aatgattttt tcgatatctt ccaagaagcc catattcaac atttcatctg
    67561 cttcatccaa aactaatgtt tgaacggttc caagtttcaa tgtgtggcgg ttaatgtggt
    67621 caagcatacg tcctggtgta cccacaacga tatgtggacg atctttcaag ccacggatct
    67681 gacggccaat atctgctccg ccgtaaacgg cttgtacacg tacttttttg tcgcgcccta
    67741 aacgatataa ttcttcttgt gtttggatag ctaattcacg tgttggtgcg ataactaaac
    67801 cttgtaattc gtgacgatct ggatcgattt tttctaacat tggtaatcca aatgcagctg
    67861 ttttccctgt acctgtctgt gcttgtccaa taacgtcttt tccagctaat gctagtggaa
    67921 tcgtttctgc ttggataggc gttgcttctt caaaaccagc gcgttcgact gatttcaaca
    67981 attctggtga taattctagt tctttaaatt tcaaatgaat cctcctatat ggttgttaac
    68041 tgaggatgta gcttttttgc taccccgtcg atttgttcgg tcaaagtgta ttgtttcttt
    68101 ttgacagtgg ccacgcacgt ttttatccat tcttagcccc tgtggcacca ccgaaaaatc
    68161 actttgcgaa gtttaggcat tagaaaagcc aaacgggtcg cgttcagctt tatcattatt
    68221 atgacatctg gcttcaacaa gttgtttcta tggcaaaacc agtccaattt ctcttcatct
    68281 ttcggcaata ggttattcta acatagtttt tcgttttctg caagtttaca gatttttatt
    68341 tcatttgctg aagttgttct accacttcaa ataagcccat gctgttgctg ccttttagca
    68401 taatactatc tgttgcttca agattttgtt tgatagcatc aatcaattta ttcttttctt
    68461 tttcaaaata gaacacaggt agttgggggt atttttggtt caattcttct tttagtgcat
    68521 gcatttgttc cccataaagg aaaatcatgg cgaatttctc aggatcgata tgttcactca
    68581 tttgcgcatg catatttaaa gactctttcc ctaattccag catatctgct aacacagcga
    68641 ttctgcgtcc ttttgttggc agatttttaa aagtatctaa taccagtccc atggctgttg
    68701 gatttgcatt gtagacatcg ctcaaaatag ctgcaccatt tcctgccgtt agccattcgg
    68761 ttctgttttg agtgatagaa acatgggcga gcccttggcg tatctcaggt atggacagtc
    68821 caaagaagcg cccgatcgta tacgcaatca aagcattcgt tacattataa cttccaggca
    68881 gcgggatcgt aaatgtttct ccttctacta caaaatcggt ttgtgctttt ccttttgctg
    68941 tcacttccgc atgaacatcg ccatttccaa taccgaatgt tgtgactgtt tgtactaatg
    69001 ttgccgttaa aggtgtcagc aacggttcat ctgcgggcac aacgagtaat ccgtctgata
    69061 caagtccgtc agtgatttcc attttggctt tagcgattcc ttctcgcgac ccaagatttt
    69121 ctatgtgtgc ttcaccgatc attgtgattg ctgcagcttt tggttgagcc ataagtgaaa
    69181 gttccgtgat ttcattggcg tgatccatgc ccatttccaa aacgatcttt tctgtatctt
    69241 ggggcatgtg caaaatcgtg taaggaagac caatattatt gttgtaattt ccttgcgtct
    69301 tatatgtttt gtatttttca gacaagacag acgcggttag atctttcgtg gtggttttac
    69361 cattgcttcc tgtaattgca acgacttctg cgcctacttt ttccaagtaa taggttgcca
    69421 attgctgcat ggctttcaaa ggatctgcta caggaataac tggaaaattt tttggagctt
    69481 gttcaacagg caagctccaa aatgaagcag atgctccgtt tgtgatcgct tgctggataa
    69541 attcatgtcc atctcgcgta ccagcaagag gaacgaataa acttccttcg gttatcttcc
    69601 ggctgtcaaa ttcgacattg gtaatctttg tcagtgcaga gcattcgctg cccacggctt
    69661 gtgcaatttc ttgtattgtt agattcattg agatctctcc taaaaaaggt tgtgaaaaaa
    69721 gcgtttggcc taaacggcgg gttcgcatga ctctcacttc caagtaaatt tctctattcg
    69781 tatttagaag ctagaatgaa cgcggttacg caatcactcc agcctcttct ttatttctct
    69841 ttattcattt ttttcaaaaa aagattgacg ctgatggtat cgattcattc ctaactggat
    69901 cagttcttca atcaaatcac cgtatttcaa gcccatattt tcccataaga gtgggtacat
    69961 actgaactcc gtaaatcctg gcatagagtt taattcattc aggaataatt catttttatt
    70021 tgtcaaaaag aaatcgcacc ggctcaatcc gcttccacct aacatcgtgt aagctaactt
    70081 cgcgtactct tgcgcttttt gataaacttc ttctggcact tcggctggaa tctgcatttc
    70141 gattttatta ttgatatatt ttgcttcata atcatagaat gctacgtctt ttacgacttc
    70201 accaggcaaa gtcgtccgaa cgtcttcatt tcctaataca gcaacttcga tttcgcgcgc
    70261 ttcaattcct tgttcaacga ttgctcgaga atcatactga taggctgttg ctaaagcatt
    70321 ttgcagctct tctcggtttt ctgcttttgt aatgccgaca ctagaaccca tattcgccgg
    70381 tttgacaaac atcggataaa gcaaagaacc ttcacattga tcaaatactt ttttaggatt
    70441 ttctttccat tgattcttaa gtactggtac ataaggaact tgcggcacac cagcagcttg
    70501 taaaatatac ttggtcatga ttttatccat ggcacatgca ctggtcaata cgcctgcgcc
    70561 gacataaggc atattcaatg tctctaagaa gccttggatc gttccatctt ccccgtttgg
    70621 cccatgtaaa actggaaaaa cgatggctcc ttcttctttg atttcgcccg gattgatcac
    70681 ttttcctgta aagccttcct ctgtctgtcc acttgggtcc catgaaagat gcaagacatc
    70741 tttgctggca ggtttttctg ttagtaatgg acctttgacc cattgtcctt cttttgtaat
    70801 aaatacgagt tgaacttggt aataattata ataaatggca tttaaaactg aaaatgcgga
    70861 aagaatggac acttcatgct ctgcgctgcg tccgccatat agtaaagtaa tcttcaaaag
    70921 attgtcctcc tgtattctaa atcgttcagt gatttactct catattttag cacaaaacaa
    70981 aaataaacga ataacttatt tataaaaaaa cgagccagct tctaaaagaa cgagcgtcat
    71041 ttattttttg tcagctagat tatttgtccc gttttttata aaaagttatg ataaagaaaa
    71101 ggagggatga tgatggcgca aacaaatcca cgcagccgct tggcagaaat cattcgagtg
    71161 ttcatcaatt acaatgtagt gccaaacttt gtacagcaaa aaaatcccga acaggtaaaa
    71221 aaagcctttg aagaactagg ccccaccttc atcaagatag gacagatgct ttctgttcga
    71281 gaagatttgc tttcttctgc cttcactcaa acattcaaaa cattacaaga tagtgtacct
    71341 agcgacacat tttcaacggt caaaaagacg atcgaaacag aactttctct ttcattatca
    71401 gatatattcg atgatttttc aaaatcgcct tttgcctctg cttctatggg gcaggctcat
    71461 cgtgccaagc tgaagaacgg tgacgcggta gtcgttaaga tccaacaccc taacatcgcc
    71521 gaagagatcc gacttgatct tcaactattt gaacgagcga tccctttgat caaatacatt
    71581 cctgaaacta gcgtagttga tctaaaaggg gtactccaag aagtaaaacg ttccttgatc
    71641 aatgaaatgg acttcttaaa agaaagtcaa aatggcgaac aattctatca aaagaacaat
    71701 ggctggaaag agatccgcag ccccaagatt tatgacgctt tttgttcgaa aaaagtgatc
    71761 gtgatggaag aaatgtctgg taaaaacttg aatcatttaa tgaacgccga aaacaaaact
    71821 gaaactttta tcactggaat tcaaaacaag cagctgaaac aagaagttgc aaagctttta
    71881 gttgagaact ttatgaaaca ggtgtttgat gatggttttt tccatgctga tcctcatcca
    71941 gggaatctgc tattccatgt actaacaaaa gaagaacaga cacaagctag ccgaaaaact
    72001 gaaacagtcc atgaaaaaga gttcggttcc tttgcttttc gagcctccac ttctgcagaa
    72061 gaccctgttg cgccatatac catcaactac atcgattttg gtatgatggg gcatctttct
    72121 gcaggactta ggcaaaaact cacacaagcc gttttagcgc tgtatacgaa agatgcttat
    72181 cgaatcgaaa aagcggtcct tcgactttgt cagcaagaag gctcgtttga tgaaagtcgg
    72241 ttccaccaag aactgacaag ttttcttgaa cagtattatg attctcctat tgatgaaatc
    72301 aacttgcaag aagtattcac acatgtcgtg acgatttgtc atcaaaataa tctgcagttc
    72361 gatcgtgata tcacgctttt gctgaaagca tttgggacat tagaaggggt gatccgcgtc
    72421 ctcgatcctg aagtttccct catggaagtc gcttcgcctt ttgctcaaca ttattttctc
    72481 actcatctgg atgtagaaga tacattgaaa caaagcggat tagacttatt ggaagggatg
    72541 aaggctgcgc ctaagatccc tcaacagctc caccatctat tagaaatgtg gacttcggga
    72601 caaggaaaag tcaatttgga attgaaaaag caagacaaat tattgagcag gatcgaaagt
    72661 atgatcaatc ggcttgtttt cggtatgatt ttagctgcat tgatcgtagg gtcctccctg
    72721 cttgtccaag cagcacctgt agaaaacgca gaggtcgttt ccttattagg gatatttacg
    72781 tatgctattg ccgcattcgt cattattttt ttggcaatcg atgcattgat ccaaatgtat
    72841 aagaagagga aaaagtagaa aaaggttgtg acagaaagaa tcagcttcaa gaaataagaa
    72901 ggggttttac ataaattgtt tctcaaattt ttgtgaaaat tcggcttatt tttcgaagag
    72961 gctacttctg aaacaccgag aataaaaaat gtgaaaaagc tgttctgcac ccagtaataa
    73021 gaacaatcaa aaagggaaca tggaacacat ttatcctgtt tccctgttcc ctttttgatg
    73081 tattcgagca taaataaaat accttcgtta cctactatct tctgtacttg gtaaacctta
    73141 gtcaattgcc ttttttaacg cttgacgaaa agacatatga tctttctccg taaagggttt
    73201 tggacccttt gtccttatgc cagcttttct taactttcca ctatgataac gttgttctag
    73261 aagcgtgccg atattcgctt cgtcaaattc ttttccagag tgatggaaca ctcgcacacc
    73321 cttcggcaat acaagtgaag ctaaaccata atcttgcgtg atcaaaaagt cattcttctt
    73381 aaccataccg acgattttat aatccgcact atcagctccg cggtctacgt agacgatttg
    73441 gacatgatta gcgtattctt tggtcgtata atggtccaca ctggtcacga taaccacgtc
    73501 aagaccatag gattctccta attttatgac atcttctttt actggagaac catctccatc
    73561 aatgaatagc ctcattcttt ttcgccttct tccataaatg ataaacagtt actaatccgc
    73621 tcagtaaaag accaacattg atccattttg ccaagataag cagttgtaca ctttctatcg
    73681 gcactgattc atggttcagc gtgatcaata atagatggat tggctctccc atttcttttg
    73741 ctaaaacaaa caaaagcgtc atcaataaaa actggtggat cacactccct ttattttgag
    73801 tagtatactt gacaacgatc cggcgatcca ttggaatagc tgtatcagtt tgataatatt
    73861 ccttatttag ccagctgcct gttactacgt gccagaaact aagcagaaag acacctatcg
    73921 caaaaccatt tggaatcaag aggaccaata aagaagaact cagtccaagc aattgcatag
    73981 ccaatggaga ccatgttaaa cgtttcaaaa tccatggtcc gactattttt gctgcaatca
    74041 agcctgctgc ataaggcaaa tacataaaaa tcgaaagttt ttctaatccg tacagtatgc
    74101 caacataaaa actgctaaat aaaaaaagga aattccctag cattccattt agaaaagtaa
    74161 acagatttag ccagcttggc aacttccatt ccttcttctg gtgtcctaaa acaaacacga
    74221 acaagatgaa cagcagcaag aaaccataaa tagcaagatc aaaaagcctt tcatcgaata
    74281 acaatcgggc atttctcaaa agaaacaata agccaaagaa tatcaaaaat aaaacaagct
    74341 ctcgcgtagc taccagattt cttttgatgt ctttgaaatc cagttcgtaa cgcggataat
    74401 gactaaccgt atggtaggcc atgacgtaaa aaagtgtata aatagtaaag cttgctgcaa
    74461 tctgagtcgg tgcaggcaac tcaatcgctt gatacaggag aaatagccag atagctgcaa
    74521 ataagtactt tttcccatcc atattgataa aaccttgcgt cttttcgtga aaattgaccg
    74581 tggtattagc aggtacaagc catgctgcac tcagccctag caaaacactt gaaaaataaa
    74641 ataaaggaaa ataaaatacg cctaatattc caagcaatga accagcacca ccaatcagca
    74701 gagcgatcat cagcaacgtg taactatcta gaccaaatcg tagactgttg actaaaaata
    74761 gtccagtcat ccgaaaggca taaaacagcg taaatggcaa aatcgtcagc caattatgcg
    74821 agtctgttag tcccaaaaat aaaagataag gaataaaaat aaccgtgtta cttaagataa
    74881 agggcgttgt ttgtgtaaaa ttacgcccaa atcgtttgag tttttcgaac atgacaatgg
    74941 ctccttaaac agtcttataa ctaatctgct cttcgatttt agcattaaag gggaaataaa
    75001 ccaattttac agaatatatt cttgtaaaaa aaaatacaga aagaagcata agcttctttc
    75061 tgcattttta cggtacttga ttactcaagc agacaagccc ttctccacaa aagtcttgcc
    75121 cgacacccct gcatccggca ggtgataaag atagaaatca attatcctgt gcctccaaaa
    75181 tcaattagga gctctgtaaa ccagagtcct tctcgacccg tcgcataaat ttactttaac
    75241 acagttccta tgtttatgcg agagcttttt tcattttata atcgaccatt tgaaatcctt
    75301 gaccgatatc tgaaataagt tcttctgtaa tctcaaatcc ttcatgctta taaacctcga
    75361 ttgcttgatg attcccctga ttcactcgca aaaagatctc tctttccttt gtttgcgcag
    75421 caagttcttc ataccagcga aaaactgaag aagtcaatcc ttgaccacgt actttattta
    75481 gcaaatataa tttacttaaa taaatttttc catttatctc ttcataagca gtgtaaccga
    75541 cagtcttttc ttcgcttttt aataaaaagt aggacacacc ttctgtcagt tctttttgaa
    75601 tctgtttttt tgactgataa gttttcagca tgtaatccac ttgtttttga ccaatgatcg
    75661 gcacaaaaac ttccggccat acttcttgta tgactgccat cagctcatcc agttcatttt
    75721 ctgttacttt tattttttcc atacacccac gtcctttttt acattataaa tgaccttgcg
    75781 cttgatggaa taaaaagagc atgatcatgc tatacacacc caccgaccac ggtttcaaga
    75841 aaatcacaat ctgcataaat tccctaaaag ataatttcgt caaaccagct actagacaga
    75901 tcaagtcgtc tggcgcaaag ggaagcagca aggtaacaac tagtactttt ttaatatctt
    75961 tcgtttttct tgtcagcaat tcatcaaatt tctgatactt ttttggcgat aaaataagct
    76021 ggacaaaggc tacgccatag taacggacaa gcaaaaatcc gattgcttcc ccaatcacta
    76081 ggccaataca actatataaa agcccaaatc cattgccaaa catcagcatg cccgctactg
    76141 aggagatccc tcccggcaaa ataggaatga tcacttggat cacttgcaac agaacaaata
    76201 tcatcactgc atacttgcca aattgctgga taaacgcttg caaagacgtg ctcgatcgaa
    76261 aaatcccatg atgataagca taaagaatca acacaaagaa aaaaaacaga ccaataatgg
    76321 gcatgatctg aagacatttt tgtaaaactg atcctttttt agacatctat attccccaca
    76381 tcttttttca tttattaaaa ctgcctcct
//
LOCUS       DADVXE010000007        70312 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.007, whole genome shotgun sequence.
ACCESSION   DADVXE010000007 DADVXE010000000
VERSION     DADVXE010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 70312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.007"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(122..499)
                     /locus_tag="KB913_000467"
     CDS             complement(122..499)
                     /locus_tag="KB913_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818856.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            755..1483
                     /locus_tag="KB913_000468"
     CDS             755..1483
                     /locus_tag="KB913_000468"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBB6818857.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1483..1737
                     /gene="purS"
                     /locus_tag="KB913_000469"
     CDS             1483..1737
                     /gene="purS"
                     /locus_tag="KB913_000469"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBB6818858.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1739..2410
                     /gene="purQ"
                     /locus_tag="KB913_000470"
     CDS             1739..2410
                     /gene="purQ"
                     /locus_tag="KB913_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBB6818859.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2411..4633
                     /gene="purL"
                     /locus_tag="KB913_000471"
     CDS             2411..4633
                     /gene="purL"
                     /locus_tag="KB913_000471"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBB6818860.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4618..6057
                     /locus_tag="KB913_000472"
     CDS             4618..6057
                     /locus_tag="KB913_000472"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBB6818861.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6080..7132
                     /locus_tag="KB913_000473"
     CDS             6080..7132
                     /locus_tag="KB913_000473"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBB6818862.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7129..7707
                     /gene="purN"
                     /locus_tag="KB913_000474"
     CDS             7129..7707
                     /gene="purN"
                     /locus_tag="KB913_000474"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBB6818863.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7704..9239
                     /gene="purH"
                     /locus_tag="KB913_000475"
     CDS             7704..9239
                     /gene="purH"
                     /locus_tag="KB913_000475"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBB6818864.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9255..10529
                     /gene="purD"
                     /locus_tag="KB913_000476"
     CDS             9255..10529
                     /gene="purD"
                     /locus_tag="KB913_000476"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBB6818865.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10651..11565
                     /locus_tag="KB913_000477"
     CDS             10651..11565
                     /locus_tag="KB913_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6818866.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11698..13263)
                     /locus_tag="KB913_000478"
     CDS             complement(11698..13263)
                     /locus_tag="KB913_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6818867.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13256..14707)
                     /locus_tag="KB913_000479"
     CDS             complement(13256..14707)
                     /locus_tag="KB913_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6818868.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14721..15737)
                     /locus_tag="KB913_000480"
     CDS             complement(14721..15737)
                     /locus_tag="KB913_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6818869.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15957..17045
                     /locus_tag="KB913_000481"
     CDS             15957..17045
                     /locus_tag="KB913_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBB6818870.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17099..18625
                     /locus_tag="KB913_000482"
     CDS             17099..18625
                     /locus_tag="KB913_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBB6818871.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18627..19832
                     /locus_tag="KB913_000483"
     CDS             18627..19832
                     /locus_tag="KB913_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6818872.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20089..21066
                     /gene="guaC"
                     /locus_tag="KB913_000484"
     CDS             20089..21066
                     /gene="guaC"
                     /locus_tag="KB913_000484"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBB6818873.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21330..22754
                     /locus_tag="KB913_000485"
     CDS             21330..22754
                     /locus_tag="KB913_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBB6818874.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23215..24324
                     /gene="pdhA"
                     /locus_tag="KB913_000486"
     CDS             23215..24324
                     /gene="pdhA"
                     /locus_tag="KB913_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBB6818875.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24327..25304
                     /locus_tag="KB913_000487"
     CDS             24327..25304
                     /locus_tag="KB913_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBB6818876.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25329..26972
                     /locus_tag="KB913_000488"
     CDS             25329..26972
                     /locus_tag="KB913_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBB6818877.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26980..28386
                     /gene="lpdA"
                     /locus_tag="KB913_000489"
     CDS             26980..28386
                     /gene="lpdA"
                     /locus_tag="KB913_000489"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBB6818878.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28548..28823
                     /locus_tag="KB913_000490"
     CDS             28548..28823
                     /locus_tag="KB913_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBB6818879.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28829..29596
                     /locus_tag="KB913_000491"
     CDS             28829..29596
                     /locus_tag="KB913_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBB6818880.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29764..31593
                     /gene="typA"
                     /locus_tag="KB913_000492"
     CDS             29764..31593
                     /gene="typA"
                     /locus_tag="KB913_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBB6818881.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31854..33626
                     /gene="recQ"
                     /locus_tag="KB913_000493"
     CDS             31854..33626
                     /gene="recQ"
                     /locus_tag="KB913_000493"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBB6818882.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33740..34042
                     /locus_tag="KB913_000494"
     CDS             33740..34042
                     /locus_tag="KB913_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBB6818883.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34045..35208
                     /locus_tag="KB913_000495"
     CDS             34045..35208
                     /locus_tag="KB913_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBB6818884.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35234..38662
                     /locus_tag="KB913_000496"
     CDS             35234..38662
                     /locus_tag="KB913_000496"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBB6818885.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38683..39807
                     /locus_tag="KB913_000497"
     CDS             38683..39807
                     /locus_tag="KB913_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818886.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39797..40234
                     /locus_tag="KB913_000498"
     CDS             39797..40234
                     /locus_tag="KB913_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6818887.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40218..40556
                     /locus_tag="KB913_000499"
     CDS             40218..40556
                     /locus_tag="KB913_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBB6818888.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40675..41235
                     /gene="rsmD"
                     /locus_tag="KB913_000500"
     CDS             40675..41235
                     /gene="rsmD"
                     /locus_tag="KB913_000500"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBB6818889.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41232..41723
                     /gene="coaD"
                     /locus_tag="KB913_000501"
     CDS             41232..41723
                     /gene="coaD"
                     /locus_tag="KB913_000501"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBB6818890.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41713..42756
                     /locus_tag="KB913_000502"
     CDS             41713..42756
                     /locus_tag="KB913_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBB6818891.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            42915..43643
                     /locus_tag="KB913_000503"
     CDS             42915..43643
                     /locus_tag="KB913_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBB6818892.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            43759..44004
                     /locus_tag="KB913_000504"
     CDS             43759..44004
                     /locus_tag="KB913_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6818893.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            44001..44219
                     /locus_tag="KB913_000505"
     CDS             44001..44219
                     /locus_tag="KB913_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBB6818894.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            44355..44894
                     /locus_tag="KB913_000506"
     CDS             44355..44894
                     /locus_tag="KB913_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBB6818895.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            44887..47160
                     /locus_tag="KB913_000507"
     CDS             44887..47160
                     /locus_tag="KB913_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBB6818896.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            47198..48244
                     /gene="holA"
                     /locus_tag="KB913_000508"
     CDS             47198..48244
                     /gene="holA"
                     /locus_tag="KB913_000508"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBB6818897.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(48333..48587)
                     /locus_tag="KB913_000509"
     CDS             complement(48333..48587)
                     /locus_tag="KB913_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBB6818898.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(48987..49256)
                     /locus_tag="KB913_000510"
     CDS             complement(48987..49256)
                     /locus_tag="KB913_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818899.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(49726..50181)
                     /locus_tag="KB913_000511"
     CDS             complement(49726..50181)
                     /locus_tag="KB913_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBB6818900.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(50319..52247)
                     /locus_tag="KB913_000512"
     CDS             complement(50319..52247)
                     /locus_tag="KB913_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBB6818901.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(52444..53277)
                     /locus_tag="KB913_000513"
     CDS             complement(52444..53277)
                     /locus_tag="KB913_000513"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBB6818902.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(53469..54173)
                     /locus_tag="KB913_000514"
     CDS             complement(53469..54173)
                     /locus_tag="KB913_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6818903.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(54196..54822)
                     /locus_tag="KB913_000515"
     CDS             complement(54196..54822)
                     /locus_tag="KB913_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6818904.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            55148..57523
                     /locus_tag="KB913_000516"
     CDS             55148..57523
                     /locus_tag="KB913_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBB6818905.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(57547..58038)
                     /locus_tag="KB913_000517"
     CDS             complement(57547..58038)
                     /locus_tag="KB913_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBB6818906.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            58225..59145
                     /locus_tag="KB913_000518"
     CDS             58225..59145
                     /locus_tag="KB913_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6818907.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            59299..59643
                     /locus_tag="KB913_000519"
     CDS             59299..59643
                     /locus_tag="KB913_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBB6818908.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(59833..60333)
                     /locus_tag="KB913_000520"
     CDS             complement(59833..60333)
                     /locus_tag="KB913_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6818909.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            60861..60944
                     /locus_tag="KB913_000521"
     tRNA            60861..60944
                     /locus_tag="KB913_000521"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60895..60897,aa:Leu,seq:cag)
     gene            complement(61268..61906)
                     /locus_tag="KB913_000522"
     CDS             complement(61268..61906)
                     /locus_tag="KB913_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6818910.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            62241..62675
                     /locus_tag="KB913_000523"
     CDS             62241..62675
                     /locus_tag="KB913_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6818911.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            62698..63018
                     /locus_tag="KB913_000524"
     CDS             62698..63018
                     /locus_tag="KB913_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818912.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            63159..63350
                     /locus_tag="KB913_000525"
     CDS             63159..63350
                     /locus_tag="KB913_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818913.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(63421..63678)
                     /locus_tag="KB913_000526"
     CDS             complement(63421..63678)
                     /locus_tag="KB913_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBB6818914.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            63836..64099
                     /locus_tag="KB913_000527"
     CDS             63836..64099
                     /locus_tag="KB913_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818915.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            64123..64311
                     /locus_tag="KB913_000528"
     CDS             64123..64311
                     /locus_tag="KB913_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818916.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(64394..64579)
                     /locus_tag="KB913_000529"
     CDS             complement(64394..64579)
                     /locus_tag="KB913_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818917.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            64794..65165
                     /locus_tag="KB913_000530"
     CDS             64794..65165
                     /locus_tag="KB913_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6818918.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(65315..65387)
                     /locus_tag="KB913_000531"
     tRNA            complement(65315..65387)
                     /locus_tag="KB913_000531"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(65352..65354),aa:Gln,seq:ctg)
     gene            complement(65433..65861)
                     /locus_tag="KB913_000532"
     CDS             complement(65433..65861)
                     /locus_tag="KB913_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818919.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(65921..66679)
                     /locus_tag="KB913_000533"
     CDS             complement(65921..66679)
                     /locus_tag="KB913_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBB6818920.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            66974..67171
                     /locus_tag="KB913_000534"
     CDS             66974..67171
                     /locus_tag="KB913_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818921.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            67277..67759
                     /locus_tag="KB913_000535"
     CDS             67277..67759
                     /locus_tag="KB913_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818922.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(67817..68413)
                     /locus_tag="KB913_000536"
     CDS             complement(67817..68413)
                     /locus_tag="KB913_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBB6818923.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            68800..70266
                     /locus_tag="KB913_000537"
     CDS             68800..70266
                     /locus_tag="KB913_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBB6818924.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT        23054 a        12025 c        14915 g        20318 t
ORIGIN      
        1 gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc aataatagga
       61 acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa aaatagagga
      121 attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga tgttgcagca
      181 agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg atacgataat
      241 gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct ttgtgttctg
      301 tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct cggcggattt
      361 ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg atcgacagca
      421 aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa agctgacctt
      481 gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa atttttagtt
      541 aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta taagattttc
      601 gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca tatttttgtt
      661 gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa aacgatgtat
      721 ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac ttttgtatga
      781 aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga tagaatattt
      841 agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa aaggagaatt
      901 gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa taaaaaatca
      961 ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa ttatccctct
     1021 ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag gtgttcccga
     1081 aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc agttggatga
     1141 tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg aagaaatcag
     1201 tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat ttgctaaggt
     1261 cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac aaattttgct
     1321 tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga atgaacatat
     1381 ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc aagaagtata
     1441 taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt cgtaaaagta
     1501 tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa aaaagcagtc
     1561 catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt tgagatacaa
     1621 cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga caagctgctt
     1681 gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga agtataacat
     1741 gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt tatgggcagt
     1801 tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct ctttagaagg
     1861 atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga gatgcggtgc
     1921 gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag aagggaaacc
     1981 agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt tgccaggtgt
     2041 actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga aagtcaaccc
     2101 caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc cagttgctca
     2161 tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa aaaataatca
     2221 gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg cagggattac
     2281 gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag tagaagactt
     2341 gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact tcggaaaggt
     2401 gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga aaaaaagaat
     2461 ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag atatcttagg
     2521 aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg aacattgttc
     2581 ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc atgtgttgca
     2641 aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag ttgtcttcaa
     2701 agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg cgacaggagt
     2761 tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt tgctagattc
     2821 attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag aagtagttgc
     2881 aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg aaattgcatt
     2941 tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt tgattgaaca
     3001 caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt atgtaggtgc
     3061 aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat ttaatcaaga
     3121 agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa agctgctgct
     3181 tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta tacaggatat
     3241 gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg gctcaggact
     3301 tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt atgaaatgat
     3361 gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg aagaaaaaat
     3421 ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag taacagacga
     3481 cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag tcgatgcatt
     3541 agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa tcgtagaatt
     3601 tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat tgcttgatct
     3661 gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg attcacaagt
     3721 acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg ttagagggac
     3781 gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt tggatccaaa
     3841 aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta gcggtggtaa
     3901 gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag aagttttttg
     3961 ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag gaactcctgt
     4021 tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct atccaacacc
     4081 aatgattggt atggtcggat tgattgagga tcataaacat atcactactc aggaattcaa
     4141 aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg atggcagtga
     4201 attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg atctatccat
     4261 tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga ttgaaagtgc
     4321 tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt tcaaacatca
     4381 gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag aaactcaatc
     4441 aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa tgatgggaga
     4501 tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt cagcaactga
     4561 cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg caatcgtatg
     4621 tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg gggtcatcca
     4681 gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg acaagaaggt
     4741 gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt ggggctgctt
     4801 tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc tgcaatcgga
     4861 catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc ttttctattc
     4921 aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa tgctcgttcc
     4981 cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga tacggagata
     5041 ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt aaaaagtgct
     5101 ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc aatgattgcc
     5161 gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa cggagcatac
     5221 gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat aagagatgtc
     5281 cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg ctttacgaag
     5341 gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc agattcaaac
     5401 atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt agcgaaagaa
     5461 tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc agccgcaagc
     5521 ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa tcaatacatt
     5581 gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg aatgaaatta
     5641 tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga ttcaattgtt
     5701 cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc aaaagaagtc
     5761 catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat tgatattcaa
     5821 acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga atgtatcggt
     5881 gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg tctggaaaaa
     5941 gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc gacgccgtta
     6001 tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt cttttaaaag
     6061 cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag ctggcgtaga
     6121 tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa aaacggaacg
     6181 tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat cggtctttca
     6241 attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat tagcagtggc
     6301 aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt gtgtcaatga
     6361 tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa cggggaaaaa
     6421 tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg ttcaaggaaa
     6481 tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag gtaatgatta
     6541 tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga caggagaaac
     6601 gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt caaatgggta
     6661 ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat caaaactgcc
     6721 agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct atgtttcttc
     6781 cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca ctggtggagg
     6841 gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa tcaaacttgg
     6901 ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa ttcctgagat
     6961 ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc aagaatcgaa
     7021 agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg aaatcgggaa
     7081 agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat gagaatcgct
     7141 gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct atcgaaaaaa
     7201 ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata tgttttgaaa
     7261 cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt tgattcaaaa
     7321 aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga tttgatcgta
     7381 ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga taaaagaatc
     7441 atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat acgtgatgcc
     7501 tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca aggtgtagat
     7561 actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac gttcgattct
     7621 ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat tagtgaaatt
     7681 attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca gataaaactg
     7741 ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt tcaacaggag
     7801 gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa gaagtgacag
     7861 ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc catggtggtc
     7921 ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa aatatccaac
     7981 caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg aaaccagatg
     8041 tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg ctccgtagtg
     8101 cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat gaagaagtac
     8161 tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa ctagcggcaa
     8221 aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta acggattggg
     8281 tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa acgcttcgtt
     8341 acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg gaaaaatatt
     8401 cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat atccgagatg
     8461 cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc gccttgaaac
     8521 acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg gaagcagcgt
     8581 atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga gaagtagatc
     8641 tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc ccttcttata
     8701 cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg acagtagact
     8761 ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt ggacttcttg
     8821 tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg acaaaacgta
     8881 agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc aaacatgtga
     8941 aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga gccgggcaga
     9001 tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa atggaaggtg
     9061 cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat gcagccaaac
     9121 atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat tctattgata
     9181 tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt agacattaga
     9241 gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa catgcaataa
     9301 gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca ggaaatccgg
     9361 ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat tcagcgttaa
     9421 tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa gttcctttgt
     9481 taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt ccgacaaaag
     9541 cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat acttatcaaa
     9601 tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg tatatcaaag
     9661 aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa ggtgtagtcg
     9721 tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac cagcatcgat
     9781 ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa gaattctccc
     9841 ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa gatcataagc
     9901 gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat tcaccagtac
     9961 cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa ccagcggctt
    10021 tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt ttgattgcta
    10081 cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct gaaacgcaag
    10141 tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta ttagagaatc
    10201 gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg gttgcagctg
    10261 ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg gaagaagagc
    10321 tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga gcaggaggac
    10381 gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa aaaatttaca
    10441 ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt ggagaaaaag
    10501 ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa aaaatacaac
    10561 aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt ggtacacttt
    10621 tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg tacttctgat
    10681 cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga agatccagta
    10741 aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc agatatttat
    10801 ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc aatcaaacga
    10861 gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt tgatttttct
    10921 aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat ggattatgtg
    10981 gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt agctgaagcg
    11041 tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa tcaaaaacca
    11101 atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa tcagctgcaa
    11161 tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat gacagatgaa
    11221 gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga tatgacgatc
    11281 caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg gaacgaaaaa
    11341 ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac gacaccaact
    11401 ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat cgccggtacg
    11461 atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat gtctcgggaa
    11521 gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt gtcataagca
    11581 ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt cagcttcgag
    11641 atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt tcgtttatta
    11701 gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa tcccttgttt
    11761 tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa aagcaatatc
    11821 tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc tttgttctgt
    11881 cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga aatgagaggg
    11941 acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg taaaattttc
    12001 tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg aaggctgtga
    12061 gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa gcgagtcgtc
    12121 ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt gcgggatttt
    12181 cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac gatataatcg
    12241 tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag atacttcgtt
    12301 tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat caactggaag
    12361 tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg aactggcggt
    12421 ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc tttctgcgac
    12481 aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat ggaccaacgt
    12541 ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa ctattaaaaa
    12601 tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc taaataaaaa
    12661 cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt ggtttgctgc
    12721 taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag caagtttcaa
    12781 tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat tttttttcaa
    12841 ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta aagcagttac
    12901 tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca gataatcatc
    12961 tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac taataaatat
    13021 gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc cgtccatgaa
    13081 aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg aagacagtgc
    13141 catctcacca tctccagctt cgccgacata agtgattgga taataagaac caaggacagt
    13201 tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa aaactttata
    13261 catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg acagttgttc
    13321 cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa taaagaagga
    13381 gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg atccctttgg
    13441 ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg ttgtctataa
    13501 ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat cctttgtgac
    13561 ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag atcattttta
    13621 aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc atatggccgt
    13681 atcttatttt taagatgact agataatcat tgatatggct aatttctttt tcaagaggaa
    13741 tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca tgggtcatag
    13801 tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc aaactgttat
    13861 aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt gctaaatggt
    13921 attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt ttattcatgc
    13981 tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag ccaaggttcc
    14041 ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg acctttctct
    14101 ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact ccaagttcca
    14161 ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt gctaagtcga
    14221 tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca gaatctacct
    14281 gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta ttgatcagct
    14341 cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac gtactaattt
    14401 ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt tcttctagga
    14461 tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc cacatacttt
    14521 ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata tttgcgatcg
    14581 tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc aaagggataa
    14641 cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg cttaaatttt
    14701 ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat attctgctgg
    14761 gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt ttgaatattt
    14821 ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt acactcgact
    14881 acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc atcaatagtt
    14941 acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc taaagcaccg
    15001 tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc atttgtttct
    15061 aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac aattcggtga
    15121 acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt tggtttacga
    15181 ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt ctctgaacca
    15241 gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt gctgacaaat
    15301 aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac gaaaagctcg
    15361 ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc tcgctttgct
    15421 tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat catatccact
    15481 ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat gtagccattt
    15541 cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc agtatgcttt
    15601 ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg gtcaggtgct
    15661 tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag ggctaaaaaa
    15721 aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta tcttatcaga
    15781 taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa acttaaaaaa
    15841 atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa aaaatcaatg
    15901 ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga taaaaaatga
    15961 aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc attctattaa
    16021 gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga atcgctatgc
    16081 cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg gaattagaaa
    16141 aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat caagtagcac
    16201 aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct atcgatggtt
    16261 cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg atcgcctatg
    16321 atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat aattttggag
    16381 taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa ggaaaaggac
    16441 cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta atcaattaca
    16501 acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc gtgccatctg
    16561 gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg gcgcaagcaa
    16621 ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct gttttgtcgc
    16681 catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg tatgggagtg
    16741 aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc gttaaatcga
    16801 tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta gcaaaaaata
    16861 cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat gatactgaaa
    16921 cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta tctgtcgata
    16981 aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc gatctgaaaa
    17041 attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga taagaattat
    17101 ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa tccgagcgtt
    17161 agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg gagaaaacgg
    17221 agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg gctcctatga
    17281 cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag atagtgaaga
    17341 aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt caataaaaga
    17401 gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg aactgacaga
    17461 aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga atcttctagt
    17521 atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat tatcaaaatc
    17581 cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag aaagcgcgaa
    17641 tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca ttatttcaca
    17701 taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg atggacagac
    17761 gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg gaatggtggg
    17821 cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag tttattttaa
    17881 agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa acgaccacat
    17941 caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg gagcgggcag
    18001 aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat ccggacgtat
    18061 attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg caaacggact
    18121 cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg atattcggga
    18181 aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag ataaagaaaa
    18241 agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa actccatcca
    18301 tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat ccaagtggct
    18361 gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag atgttggggc
    18421 aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag ctgtctgtct
    18481 tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata cgatgaacga
    18541 aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct tgatgaaatt
    18601 aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg gataaaaaag
    18661 agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac agcatggtga
    18721 tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt ttctggcgtc
    18781 cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta gctgcaggga
    18841 tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg atggcgtttg
    18901 ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg atgacagtta
    18961 tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg gtagcttatg
    19021 cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt ggactgacac
    19081 aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa aaaatgtcta
    19141 cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca ttgattttag
    19201 gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat cgtcggaaaa
    19261 atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta tttacagcag
    19321 tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg attattttga
    19381 tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca gtagcaggtc
    19441 gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg atcaaaacaa
    19501 agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta gctggattag
    19561 ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg gaactggatg
    19621 caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga acaatcatgg
    19681 gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg attttaggcg
    19741 tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc gttgtgctag
    19801 acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca gaaaaaagac
    19861 tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca ttgtttcgtt
    19921 tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc tttttgctct
    19981 tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc ttgattaaat
    20041 taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat gaaagtattt
    20101 gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg ttctgaatgt
    20161 gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc tgccaacatg
    20221 cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta tttctatatc
    20281 atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa aaagcgtgga
    20341 ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat agagaagttg
    20401 gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg acatgctaac
    20461 tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt tgtgattgcc
    20521 ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc agatgcaaca
    20581 aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg ctttgggact
    20641 ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa gccgatcatc
    20701 gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt tggtgcgaca
    20761 atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga aacaaaagtc
    20821 gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca aaaaggcgaa
    20881 aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt gaaagataca
    20941 ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg aagagatctg
    21001 gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa tggagacaca
    21061 atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca ttaagtaata
    21121 agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt attatcgcag
    21181 atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt tttgtcacag
    21241 tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta aaatcaaaag
    21301 aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa aaacaaggac
    21361 cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga aggatcaatc
    21421 ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg aatcgttcca
    21481 ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc aaacgtggca
    21541 gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga atcgattggc
    21601 ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa ataagagaag
    21661 caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg ccagatgagc
    21721 ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg gaagaaaaag
    21781 aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat ttggaaagta
    21841 aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt cagcaagcaa
    21901 tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta gagtcacctt
    21961 ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt gggataccga
    22021 tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa aataaattga
    22081 aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg agtcaaaaac
    22141 gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt gaagacgatg
    22201 tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga acgattgatc
    22261 cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca acgaaaatcg
    22321 gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa gaaatgatgg
    22381 agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat gaagcaattg
    22441 atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg ataagcgctt
    22501 ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac tatgcctgga
    22561 ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta gatatgggtc
    22621 ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga atcaattaca
    22681 gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt ctagaaaagt
    22741 ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct tggatttaaa
    22801 tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact aagaaaaaac
    22861 cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa caaaactgta
    22921 taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa aatagaaaaa
    22981 atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat gctgttaata
    23041 tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt gtatttctca
    23101 taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt tattcactgt
    23161 ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg acaaatggca
    23221 aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc agatttccca
    23281 gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt acctgattta
    23341 tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt attagaccaa
    23401 cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac tgctggacaa
    23461 gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct tcttccaggt
    23521 tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc ttttttatgg
    23581 tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct accaccacaa
    23641 attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt gaagaaacga
    23701 aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca aggtgatttt
    23761 tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta tatccaaaac
    23821 aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac acttgcacaa
    23881 aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc gcttgcagta
    23941 tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc agtcctaatc
    24001 gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc aacccgctac
    24061 cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg cttccgtaaa
    24121 tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat cgaagcaact
    24181 aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca aaaggtttca
    24241 gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca aattgcaatt
    24301 tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa gcaatcacag
    24361 atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt gaagatgttg
    24421 ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc ggagaagacc
    24481 gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc ggtcttgcgt
    24541 tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc gaagcaatgg
    24601 acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact agaaatctac
    24661 ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg cattcggata
    24721 atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct tccaaccctt
    24781 atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt gttttcctag
    24841 aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct tacgaagttc
    24901 ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc acatacggag
    24961 caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat atatctgttg
    25021 aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt caatccgtgg
    25081 aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc gttgccgcgc
    25141 aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca atcggacgag
    25201 tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg ttgccaaatg
    25261 caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag aagggacgaa
    25321 acaaagtcat ggcttatcaa tttaaattgc cggatatcgg tgaaggaatc gcagaaggtg
    25381 aaatcgtcaa atggttcgtc aaaccaggag atacgatcaa tgaagatgat acattactag
    25441 aagttcaaaa tgacaaatca gtagaagaaa tcccgtcacc tgttacagga acggttaaaa
    25501 atgtgattgt tccagaaggt accgtagcaa atgttgggga tgtattagta gaaatcgatg
    25561 caccaggaca cgaagacaat gaaggggaca gtggtgtagc cgcagaatcc caaactccag
    25621 ctaaaccggc tgctgaaccc actgttgata cagaatcagc tggatcgtca agcgaaggag
    25681 tcttccaatt taagttaccg gatatcggtg aaggaatcgc agaaggtgaa atcgtcaaat
    25741 ggttcgtcaa accaggagat acgatcaatg aagatgatac attactagaa gttcaaaatg
    25801 acaaatcagt agaagaaatt ccgtcacctg tcacagggac agttaaaaac gtgattgttc
    25861 cagaaggcac tgtagcaaat gttggggatg tattagtaga aatcgatgct cctggacaca
    25921 atagtgcacc gtcaactagt gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat
    25981 caggttcagc aagtgtcgtt gaagctgccg atccaaataa acgtgtattg gctatgccat
    26041 ctgttcgtca atttgcccgt gaaaaagatg tagatatctc acaagtaact gcaactggaa
    26101 aaggtggcag agtaacaaaa gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg
    26161 caccagcgaa atcagaagcg ccagaagcgg cagcaccgaa agaagcagct cctgcagcag
    26221 aaagcaaacc agctgcacca gcaaaaccat tcaagtccaa cttaggagac ttggaagaac
    26281 gtgtagcaat gacgccaaca cgtaaagcta tcgctaaagc aatggtcaac agtaagcata
    26341 cagctccaca cgtgacattg catgatgaag tagaagtgtc taaactatgg gataatcgga
    26401 aacgatttaa agaagttgct gctgcaaatg gtacgaaact tactttcttg ccatatgtcg
    26461 tgaaagcttt aacagcgact gttaagaaat acccagtatt gaatgcatct atcgacgatg
    26521 caaaccaaga aatcgtttat aaacattact acaatatcgg tattgcaact gatacggatc
    26581 acggactata tgtaccaaat gtgaaagatg cagaccgcaa aggaatgttt gctattgcag
    26641 acgaaatcaa tgagaaagca aaattagctc atgacggcaa actatctgca gaagatatgc
    26701 gcaatggaac aattacgatc agcaatatcg gatctgtagg tggcggttgg tttacaccag
    26761 tcatcaacta tccagaagta gctattttag gtgtaggaac gattgcacaa caaccaatcg
    26821 taaatgctga aggcgaaatc gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc
    26881 accgtatcgt agatggagca actgcgcaac aagcaatgaa taatatcaaa cgtcttttag
    26941 ctgatccaga gctattaatg atggaaggat gataaacaaa tggtagttgg agattttgct
    27001 gtagaattag atacagttgt aattggtgcg ggacctggtg gctatgtagc tgccatccgc
    27061 gctgctgaaa tgggacaaaa agtagcaatc attgaaagag agtatattgg cggtgtttgt
    27121 ttgaatgtcg gctgtattcc ttcaaaagca ctgatagctg caggacacca ttatcaagag
    27181 tcactagatt ctgaaatgtt tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa
    27241 acacaagaat ggaaagaaaa caaagttgtc catacgttga cttctggtgt tggtttccta
    27301 ttaaaaaaac ataaggttga aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca
    27361 ctacgcgtca ttcatccaga ttcagctcaa acttattcgt tcaataacgc aatcatcgca
    27421 acaggttccc gtccaatcga gattccagga tttaaattcg gaggacgtgt gttagattct
    27481 actggcggat tagcattgaa agaagtacct aagaaatttg tgatcatcgg tggcggtgtg
    27541 attggtgccg aattgggcgg agcgtacgca aacttaggag cagaagtaac gattcttgaa
    27601 ggctcaccac aaattttacc aacttacgaa aaagatctag taaaattagt agaagatgat
    27661 ttcaagaaaa aaggcgtaac agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac
    27721 ggtgacagcg tgacagtgaa atatgcagtg gacgggaaag aagaatccgt tactgctgat
    27781 tatgtgatgg tcactgtagg tcgtcgtccg aatacagatg atatgggctt agaacaagcg
    27841 ggtgtcgaag taggagaacg aggattgatc acggtggata aacaaggacg tacgaacgta
    27901 cctaacatct atgccatcgg tgatatcgtt ccaggggcgg cattagcaca caaagccagt
    27961 tatgaagcaa aaatcgctgc tgaagcaatc tctggcaaaa aagtagctgt agattataaa
    28021 gcaatgccgg cagtagcctt cactgatcct gaattggctt ctgtaggtat gacgatcaaa
    28081 gaagcaaaag atgctggtat cgaagcaaaa gcatataaat tcccattttc agggaacggt
    28141 cgggcattat cgcttggtaa aacagaagga ttcatccgtc tagttacgac gatcgaagat
    28201 aacgtgctta ttggcgcgca aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta
    28261 gctttagcaa tcgaatcagg aatgaatgct gaagatatcg ccttgacgat tcatcctcat
    28321 ccatctcttg gcgaaatcgt catggatgct tcggaattag cattaggttt accaatccat
    28381 atttgatttg aataatacag gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta
    28441 gaattatcaa taatattatt atgtaaactt aaaaatatga caacttcttg gtttattacc
    28501 acttcctatg ctacactgaa gaggaatatg aaataggaga gttgaagatg caagaatatc
    28561 agtatccact tgatttagat tggacaacag acgaaatggt cattgtaatg aagatgtggg
    28621 aagatctgga acgtgcgaat gaaaaaggga taaacaatga agcttttttg aagacttatc
    28681 agcagtttaa aactgttgtc aaatccattg gtgaggaaaa acgattggga cgggaatttg
    28741 aaaaagcttc cggttattct ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca
    28801 aaactttgag aatgaacggg tgagataaat ggaacagatg attgatcata tcaagtcctg
    28861 gcttgaagaa gctggtgaga aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa
    28921 atcaaatcga acggatctag taacaaatgt cgatcgaaac atccagaatt ttctaatcga
    28981 aaaaatccat tcctttgatc cagaggcgaa aatattggca gaagaagaag ggtgtaatca
    29041 attatcggat ctcgatggaa gagtctttat catcgatcct attgatggca ccttgaattt
    29101 tgtgattgaa ggggaaaatt tttgtattat gctcgctgtt tatgaatccg gcgttggaaa
    29161 gcttggtttc atttatgacg tgatgagaaa tgaacttttt tggggtggaa aaggaatagg
    29221 cgtgtataaa aatgatgagc cattgcctag accagcaaat aaatccttat cggaaggctt
    29281 acttggtgtg aatagttatc ttttcggtca taataaatat ggaatccgag aaattgcgga
    29341 aagcagcatg gggacacgta tgtacggatg cgctggtctt gaactagtgg caatcttgaa
    29401 aggaaaccac attgcttata tttcaaacct tagcccttgg gattatgcag cgggaaatgt
    29461 cttattggaa gagtttggta tggtaacaag cggtcttttt ggtactcctt tgacatttga
    29521 aaaaagggaa tactatttag cagggacttc ttgtgcatat gcagaaatcg cagacctttt
    29581 gaaaaaagaa ggctgaaaaa aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa
    29641 agattaattt tctcgaaaaa atgaaaacat tttactatat ttcatgaaaa aagtctgcta
    29701 taattagcag tcgagtaaaa tttgccctgt cataaagaac caataaaaaa ggagttagtt
    29761 acattgaatt atagaaacga tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga
    29821 aaaacaacat tagttgatga actattaaaa caatcagata cattagacgc acatacgcaa
    29881 ttgcaagaac gtgcgatgga ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta
    29941 gccaaaaaca cagctgtaga ctataaaggt attcgcgtaa acatcatgga tactccagga
    30001 cacgcggact tcggtggcga agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg
    30061 gtcgtagatg cgtatgaagg aacaatgcct caaacacgtt ttgtattgaa aaaagcactg
    30121 gaacaacata tcacaccaat cgttgtcgta aacaagattg acaaaccttc tgctcgtcct
    30181 gagcatgtcg tagatgaagt tcttgaacta ttcatcgaat taggagcaga tgatgatcag
    30241 ttagactttc ctgtgattta tgcatctgca ctaaatggta cgtcaagctt gtcagatgat
    30301 ccagcagatc aagaaccaac catggcacct atttttgata caattattga aaaaatccct
    30361 gctcctgtcg ataacagcga cgaaccatta caattccaag tttcattact tgactacaac
    30421 gattatgtag gtcgtatcgg aatcggacgt gtatttagag gaacaatcaa agtaggagac
    30481 caagtagcat taattaaatt agacggaaca gttaagaaat tccgtgtaac gaaattattt
    30541 ggtttctttg gactaaaacg tctagagatt caagaagcaa aagctggaga cttgattgct
    30601 gtctcaggta tggaagatat ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat
    30661 gcgttaccta tccttcacat tgacgaacca acattgcaaa tgactttctt agttaataat
    30721 tcaccatttg ccggtcgaga aggtaaattc gtaaccgctc gtaagattga agaacgtttg
    30781 atggcagaac ttcaaacaga tgtatcctta cgagttgaac caacaaactc tccagatgca
    30841 tggacagttt ctggtcgtgg agaattgcat ttgtctatct tgattgaaaa catgcgccgt
    30901 gagggatacg aattgcaagt atctcgtcca gaagttattg aaaaagaaat cgacggtgta
    30961 aaatgcgaac cgtttgaacg cgtgcaaatc gatacaccag aagaatatat gggtagtgtt
    31021 atcgagtcct tgagcttacg taaaggtgaa atgcaagata tggtccatac aggaaacgga
    31081 caaatccgtt tgacattctt aacacctgcc cgcggtttga ttggttattc aactgaattc
    31141 ctttcaatga cacgtggtta cggaatcatg aaccatactt ttgaccaata tctgccaatg
    31201 cttcctggtc aaattggcgg acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa
    31261 gcaacgactt attctatcat gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt
    31321 acagaagtat atgaaggaat gattatcggg gaaaacagcc gtgataatga tttgactgtc
    31381 aacatcacga aagcaaaaca aatgacaaac gtacggtctg ctactaaaga ccaaacatct
    31441 gtcatcaaaa aaccaaaaca attgacgttg gaagaatctt tggaattctt gaatgatgat
    31501 gaatattgcg aagtaacacc agaaagcatt cgcttgagaa aacaaatttt agagaaaaat
    31561 gctcgtgaaa aagcatctaa aaagaaaaaa taatctgtaa aaggatgaag agagaaacca
    31621 gcttgttata aaaaatagct ggtttctttt tttgtccaac tcttttctgt ggagaagtca
    31681 tctttgtcaa tggacataaa ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa
    31741 aaacttattt ctagagagtt tttgtttcat aataagataa tgtttcacga aaggagatca
    31801 acttgtcctt cgaagaaaat cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg
    31861 acttattaaa acaatacttt ggctatgatg agtttagacc tggtcaaaaa gaaattatcc
    31921 agaaagtcat tgatcaggaa aatgtattag gaatcatgcc taccggaagt gggaaatcaa
    31981 tctgttacca gcttccagct ttactattag atgggcttac tgtggttgtg tcccctttaa
    32041 tctctttgat gaaggatcag gtggacgcgg cgaatcaatt aggtataccc gccactttta
    32101 tcaatagctc gttagatggt tacgaaacag ctagacgctt ccaagaaatc gatagacagc
    32161 agtaccgttt actttatatc gctcctgaac gttttatcat gccggatttt atccaagcaa
    32221 tgaagcgatg gaacgtccgt atgatcgcta ttgacgaggc acattgtatc tctcagtggg
    32281 ggcatgattt ccgcccaagt tatttacaga tggcgaacca gctagatcaa ctgccaaatc
    32341 gtcctgtaat tgttgctttg acagctacag cgactgtgca agtagctgct gacataaaaa
    32401 gacttttaaa aattccagaa aacaaccata ttcagactgg ttttgaacga gaaaatctac
    32461 gatttcaagt aattaaagat caaaaaaaag aacaatatct aatcgaatat ttaaagatca
    32521 acaaaaatca atctggtatc atttatgcag caacgagaaa agaagtagac cgtctctatc
    32581 atttgcttaa aaaattcgat ttttccgtgg gtagatatca tggtggtcta aatgagaatg
    32641 agcgaacaga aatgcaagaa gcctttttat acgatcgctt gcagctgatt gtagcgacaa
    32701 atgcatttgg tatgggtata aataaaagca atgtccgttt tgttatccat tatcaaattc
    32761 ctggctctct agaagcatac tatcaggaag ctggtcgggc gggaagagat ggtctttcca
    32821 gtgaagccat cctgcttttc tctcctcaag atatccaagt ccaaaagttt tttatccagc
    32881 agtcccaaag agaagaaggg caaaagcaaa aagaatatga aaaattaaaa gcgatgacag
    32941 aatacgtgta tattgagtcc tgtcttcagc aatacatcct aaactatttt ggcgagacaa
    33001 gcagtccgtg caaccgttgt ggtaactgtt tagatgacag agaaatagta gaagtaacga
    33061 cagaagcaca gatggttctt tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa
    33121 tgctgatgaa agtcttagca ggatcgaaag aacaaaagct gcaagcttta ggttttggac
    33181 atttatctac ctatggactg atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg
    33241 aatatttgat atcgaatggc tatcttctga ccatcaatgg tgagtatcct gttttgaaag
    33301 taacagaaag agggatacaa gtattgaaag gacaagaatc tgtttatcga aaggaaccca
    33361 agaaagtcca gcagctatcg gatgaagaaa ccgatacact atttgaagtg ctgcgggaac
    33421 tgcgaacgga tctagcatca gaagcaggcg ttcccccgta tgtcgtattt tcagattcca
    33481 cattgaaaga aatgagccga atacgtccat caagcagatt ggagatgctt cagataaaag
    33541 gagttggcca aagcaagctt gataaatatg gcgaagcctt tttatctcgg ataaaaaatg
    33601 cggactctaa cgttctggat aagtagaaag aacgaatacg taaaaatgaa taaaaacaac
    33661 tggttaaatc tgtttttttt gctccttatg aaaatcaaat atgttataat taaggaatta
    33721 gaatgggagg taagcacaga tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa
    33781 tgatgaagca gaacggatca aacgattaat ccgaaatcaa aacaacagtc tctgtatctc
    33841 acaatgcaaa gccttcgaag aagtggtaga tacacagatg tacggctttt cccggcaagt
    33901 cggttttgct gtccgtatag gagtaatcgg aaagaacgag ggccagctga tgttaagtga
    33961 gctagaacga gaattgaatc agttatatag tgaggtttac caagaaattt atgataaaaa
    34021 agaagttggc aaggaggaat agacttgcct aagaaagtga aaaaaaggca tctattagac
    34081 tatagcatct tgattcccta tttaatttta tgtgtattgg gattgatcat ggtatatagt
    34141 tctacgtcgt atctattatt agaaaacgga caaaatccgt ccgcatcagt cattaaccag
    34201 agtatttttt gggtgcttag cttgattgct atcgcactac tttataaaat gaaaacagat
    34261 gttttgaaaa accagcgttt gatcatggca gccatcgcag ttttgacgat tttgctgctg
    34321 attgttgtgt tttttggtaa ggagatcaat ggggcgaaag gttggctgca aattgcagga
    34381 ttctcgatcc aacctgccga atacctaaaa atcatttcta tctggtacct gtctctgact
    34441 ttatctaaaa gacaaaacag tgtacaaaaa gattttcttg ggactgtgaa acgtccactt
    34501 gcaatggtta tcggacttac tgcattagtc gctattcttc ccgattttgg taatgcggca
    34561 gttatctttt tgattatttt ggttctgctt ttagccagcg gagtcaatta tgtgtatact
    34621 ttgattgtag gagtaggagg cttttgtcta agtactttta cgatctggct gatcaatatc
    34681 acaaacggaa agatcttacc cggacgttta cagtatatct ataatcgatt tgctatttac
    34741 caaaatcctt tctcagacga attaaataaa gggcatcaac tagtcaacgg ctactatgcc
    34801 atgttcaacg gaggactatt tggcagggga ttaggtaaca gtatccagaa aaaaggattt
    34861 ttacaagaag cacaaaccga ttttatttat gcaatcgtag tggaagaact gggagtgatt
    34921 atggggattt tgatattagc gttgctattc tttatgattg tgcgcattgt ccttgtaggt
    34981 atccgttcaa aagatccgtt caattcgctt ttgtgcattg ggatcggcgc aatgtttttg
    35041 atccaagtat ttgtcaatct tggaggaatt actggcgtta ttcctttgac agggatcacg
    35101 ttcccatttt taagtcaagg aggctccagt ttgctgatgc tttcgatttg tgtcggcttt
    35161 gtcctcaaca tcagtgcgga tgaaaaacgc aagagcttag gtttataata aaaaaagatg
    35221 taggagtggt tcgatgaaaa aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt
    35281 atttcgtgct tgtacagaat taggaattaa aactgttgga atctatgcag aagaagatga
    35341 atattccgta caccgtttca aagcggatga agcatattta gtaggacaag gaaaaaaacc
    35401 gattgatgcg tatctagata ttgaagggat catttctatc gcgaaagaat gcggagctga
    35461 cgctattcat ccgggttacg gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga
    35521 agaagaaggc atcatttttg ttggacccaa actgcatcat ttagatattt ttggagataa
    35581 aatcaaagca aaagctgcag ctatcgaagc ggggattgct tcgattccag gcacagatgg
    35641 accaatcgct tctatagacg atgccttgga gtttgcgaaa caatacggtt atccgattat
    35701 gatcaaggca gctctaggcg gcggcggacg cggcatgcgt gtagctcacg atgaaaagag
    35761 tgcaagagag ggctacgaac gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga
    35821 agtgtatgtt gaaaaataca tcgctaatcc taagcatatc gaagtacaga ttctcgggga
    35881 tacgcatgga aacgtcatcc atctttttga aagagattgt tctgttcagc gccgtcacca
    35941 aaaagtagta gaagtagcgc cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg
    36001 ccaggcagct gtccaattga tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt
    36061 tcttgttgaa ggagatgatt tttactttat cgaagtcaac cctcgcgtcc aagtggaaca
    36121 tacgatcaca gaaatgatta cagatattga tatcgtaaca acgcaactgt tgattgctca
    36181 aggtttggat ctgcataaag aaatcggatt gcctcagcaa gaaggaatta aattaaatgg
    36241 ttcagccatt caatgccgaa tcactacaga agacccgttg aataactttt taccagacac
    36301 agggaaaatc gatacgtatc gttcacctgg tggttttggc gtacgtctgg atgtcggaaa
    36361 tgcttacgcg ggctatgtag tgacaccgta ttttgattca ttgctagtaa aagtatgtac
    36421 gcatggtgct acctttgaaa cagccattca gaaaatggaa cgttgcttga aagaatttag
    36481 aatccgtgga gtgaaaacaa acattccatt tatgctcaat gtcatcacac atcctgaatt
    36541 ccaatcagga aatgcaaaaa caaccttcat tgatagtaca gcaacattat ttgaatttcc
    36601 tcgactacga gaccgcggaa acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg
    36661 ttttccaggt atcgaaagtg gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga
    36721 tctaatcaca agaactgatt acgtaacggc taagaatgta ttagatgcga agggtgccga
    36781 tgctttggtc gaatggatca aaggacagga aaatttgttg ttgacggata cgacatttag
    36841 agacgcccat caaagtctgc tagcaactcg tgttcggaca aaggatttca agcagattgc
    36901 acgtttgact ggagaaggtc ttcctgaact cttttcaagt gagatgtggg ggggagcaac
    36961 atttgatgtg gcttaccgct ttttgaatga agatccttgg caacggttga gaaaaattcg
    37021 ttctttaatg cctaatacgt tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta
    37081 ttctaattat cctgacaatg tattggtgga atttgtcaaa gaagcagcag cgcaaggaat
    37141 cgatgtattt cgaatctttg atagtttgaa ctggactcca caaatggaaa aaagtatcca
    37201 agctgtacgg gatactggta aaatcgcaga ggcagctatt tgctatactg gcgatatcaa
    37261 cgatccaagt cgggcaaaat acaatgttca gtattataaa gacatggcaa aggaactaga
    37321 acaactgggt gcgcatatca ttgcaatcaa agatatggct gggctgctta aaccgcaggc
    37381 agcttatcgt ttgattagtg aattgaaaga aacgacagat ctgccaatcc atctgcatac
    37441 tcatgatacc agcgggaatg gaatcatcac ttattctgct gcttcaaaag caggagtaga
    37501 catcgttgac gtggcaatga gtgcaatgag tgggaatact agtcagccta gcatgagcag
    37561 cttgtattat gcactggtca atggtccacg gctgccagaa atcacgattg aaaatgcaca
    37621 gaaattaaac cattattggg aagatgtgcg catgtattac aaaccgtttg aaaacggctt
    37681 gaatgctcct gaaacagaag tatatatgca tgaaatgcca ggaggacagt attcgaatct
    37741 acagcaacag gcaaaagctg tcggattagg tcatcgctgg gatgaaatca aacaaatgta
    37801 tcatactgtc aacttgatgt ttggcgatat cgttaaagta actccatcat ctaaagtagt
    37861 tggagatatg gcactattta tggtccaaaa tgatcttaca gaagaagata tttatgaaaa
    37921 aggcgaaaca ctaagtttcc ctgaatctgt tgtgactttc ttccaaggag aactagggca
    37981 acccgttggc ggatttccta aaaaattgca aaagattatt cttaaaggca gacctgcatt
    38041 gaatgaacgt ccaggtcttt tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt
    38101 ggcagaaaaa attggctatg aaccaaaaca agacgaagta ttaagctatt tgatgtatcc
    38161 gcaagtcttt ttggactatc aaaaagcata taatcaattt ggcgatgtta cattactgga
    38221 cacaccaaca tttttccaag gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg
    38281 cggaaaaacg cttatcattc gtttagatga aatcggagaa cccgatatcg aagggaatcg
    38341 cgtactgttc ttcaatttga atggacaaag acgtgaaatc actatcaaag ataattcgat
    38401 catcagtacg gtccaaaccc gattgaaagc tgaaccgaca aaccgagaac aaattggagc
    38461 aacgatgtct ggttctgttt tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg
    38521 tgatacgttg atgattactg aagcgatgaa aatggaaacg gccatcgaag cacgttttga
    38581 cggagaagtc gcacatgtat atgtgtcttc aggagacact atttcgtctg gtgacctttt
    38641 gattgaagtg actgagaaat aataagcgaa aggtggggaa acatgaaaag actgggtttg
    38701 ttttggctga ttctgctatt agttattgtg gcattctaca tggaaccagt cttgtttccg
    38761 ccaaaacttg aagtgaagga aaactctgat caacaaatat caaaccaaat gacaacgtgg
    38821 aaataccagg agcttaaagc aactggtttt tctacttata tcggaaaacc gatcgatcag
    38881 ctggaaaagg attttggcca agcctatgat cgattaacta gcggatttgg ttttgaaaca
    38941 agatattatg aaaataaagc tagtcatctc acatttgaag cgaacatcca agacagcaga
    39001 gtcacaactg ttaaagtact gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg
    39061 atgacgatgc aagatcttac gaaaatcact actatctata ctaatttcac ttttgagtac
    39121 catgatacag aagttggaat cgaactaatg gaagaggata tgaattatcg tccgctaatt
    39181 gcttttgata acgacacttt tgctatttta ttttttgatc aaacaacaaa cggcctattt
    39241 tcagttgtgt atttagataa agatagtctt ttgaaactat tgccatatca agtgtttggt
    39301 gaaggccttc cacattatca agcagataaa tcggctgatt gggaatcaat caatcgcgtt
    39361 aaagaacgaa aaagtacgac tttattaaat atgcttagaa gagaagacga acttcccata
    39421 tacaatcaaa cacttgcctt tcaaaaccac agtcagctgc tactacatga ttttttgaca
    39481 aggcctgagg aaatattgtc agaggaacgt atggctgatt ggcaaaaatc gctaggcagt
    39541 gctcaaacga cagtgaaatt ctcactgacg aatgatgaat tggagaagtt aatcagtaaa
    39601 caaaaattag aaaatactag tgggctattt attcatccgg cgattgacgc tactttttcg
    39661 tttttatatt ggtacagcga tccttacaac catgaccgtt tcatggaccc gggaacggat
    39721 tctgtaggca ttgctttttc taaagaaaat atgttagtct tattgcaaga agaaaacgga
    39781 gaaagtagtg atagcagtga tcgttaacga agagctgttt caactggagg atcaatgcct
    39841 ccaagtcgct gaaatgataa aaaagagtaa aacgatggct tcttatcttg aacataaaca
    39901 gtcaatggaa gaatctgcaa aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga
    39961 agcatttgaa aatgtagcgg catatggtga gtatgcacct gattatcgtg aaaaaaaacg
    40021 agctgttcga aaagcaaaaa gacagcttga tatggatgag catgttgcag ctttccgata
    40081 tagtgaaaca cagctgcaaa gtctgttgga tcaaattgtc caagtacttg ccgaagaagt
    40141 ttctaatgaa atcaaagtag atgcaggtag cccgtttttt gaaacgaaaa aacactttgg
    40201 atgcggaggt aattgtcatg caattagaca atagtgaatt tgaaataaca aaacgacgcg
    40261 ggctgatcgt atgggtctac agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt
    40321 tgcattatgt ctcaagaaga atgaaatatg tcgtgcttta cttaaatgaa gagacattgg
    40381 aagaaacaga agaacgaatc cgtaaattac attttgttcg aaacgtagaa cgttcttacc
    40441 gaccggatat cgaaatgaat tttgccgaaa aaataggaaa caaaacagta ttaaaagacg
    40501 aaggtttcga aattgaagag ctaaatacag aaatccgatt agctgaacat ctttaaaaat
    40561 ctcttatgag cagtttttaa ataaaaaata acttggataa cgatcgattt ttgatcattg
    40621 tccaagtatt tttttggtat actagtacca gtaccatttc taaggagtga gtagatgcgg
    40681 ataatatcag gaaattatgg cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga
    40741 ccaactacag ataaagtaaa agaatccata ttcaatatga ttggaccata ttttgatgga
    40801 gagacagtat tggatctgtt tgcaggaagc ggtggtttag ctatcgaagc agtatctaga
    40861 ggctgcagtc atgcggtatg cgtagacaaa aattaccaag cgctaaaaat catcaaagaa
    40921 aacatcgaaa ttacgaaaga accagagaaa tttaccacaa taaaacttga tgcggacaaa
    40981 gcaatcgaac ggctagcagc ggagaaacaa caattcgact acttgtttct tgatccgcca
    41041 tatgcaaaac aaaaaataat cgatcaaatc cataaaatgg aagaactggg acttttttct
    41101 aaaaccgcag ttatcgtatg cgaaacggat aaaacagtcg aattgccaga aactgtggct
    41161 ggattccatc aaataagaaa acagatttat ggcataacgg ccgtaactat ctatagaaaa
    41221 gagggaaatc aatgaaacgt gcattattcc caggaagttt tgatcctttt acaaaaggtc
    41281 acttagatac ggtggaacgt gcggctaaat tattcgatga ggtagtaatt ggtgttttta
    41341 tcaatacttc aaagaaaagt ttgtttcccc cagaagaaag aatgacattg atcacaaaag
    41401 ctgtttctca tcttcctaat gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa
    41461 cagcaaaaga gattggtgca gatgcgttga tcagaggcat acgaagtatc aaagactttg
    41521 aatatgaacg agagattgct cagatgaatc atcatctata tgatgaattg gaaactgtct
    41581 tcttattagc aaaaccagaa tatagtcacg tgagttccag tattttaaaa gaagtactgc
    41641 actttggcgg agatgtgagc agctacttac cgccagtgat caacgaagct ttagctggaa
    41701 agcgtgaatc aaatgaaagc taaacaatgg ttgaaaacag tactgattat catatttgga
    41761 atgttgatca ttggatttgt agtagttccc ttgccgtatt atgtagaatc accgggagcc
    41821 acgatcgatc tgaaagaact aattacggtc aatgataagg aagataaagg ttctgggtct
    41881 ttctctctta cctctgttgg tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa
    41941 atgacccctt ttgaagaatt gatcagtgaa gaagaattga ctggtggggc gacaaatgaa
    42001 gaatataatc aaatgcaaca gtattatatg gattcttccc aaaatgcagc aatcgaacaa
    42061 gcgttaaaac ttgcagacaa gccttataaa atggaattca aaggcgtata tgtcatgagt
    42121 gtagagaaaa catcgaattt ctttggcaag ctttcagttg gagatacagt aacaaaagta
    42181 gacgggaaaa gctttcaaag tacagaagca tttatggatt atgtaaaaag ccaaaaagtt
    42241 ggacaaacaa tcgaaatcag ttatttgcat aatggtgaag aaaaaacagc ttctggtgat
    42301 ctgatcgagt taccaacaga taaaaaggca ggaataggta tcacgcttac tgaccatacc
    42361 gagatcgaat cagatacaga tgttcgtatt aattctggct ctatcggtgg gccatcagcg
    42421 ggattgatgt tcactttaga aatctatgaa caagtcactg gtaaaaactt gcgacatggt
    42481 aagcaaattg caggaactgg aacgatcaac agtgaaggag aagttggccg aatcggagga
    42541 atcgataaaa aagtggcaag tgcggataaa gctggcgtag agattttctt tgcaccagat
    42601 gatacgattt cagacgatgt taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa
    42661 gcaaaagctg ccgctaaaaa attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta
    42721 caagaagcgc ttgactatct agagaaaatg aaatgaaact aaataattaa agaggggttg
    42781 tgacacgagt tctgtcacaa cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa
    42841 acaaaagaaa aaattgacgt aattagatgt tgaagggacg attttgccag agctcactgt
    42901 ttcttcaatt ttaaatgaaa ggagtaatga atgattttta ctggtcattc tttgaaaaaa
    42961 gaacaatgat agaaaaaatc agcaagaaaa tactagcttc acccaaattg atcatttgga
    43021 tgtctatgat agttcttatc ttttgtatcg caagtggttt tttattatca aatttgctat
    43081 tttatagaga aacagaagag actgctgcaa aagaaatact ttcttcgttt agttccagtg
    43141 gagaagatcc atcagctgaa ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt
    43201 acaccgatat caaaggaagt gtgaaggagc ctggtatcta ttccttttct tcagaagaac
    43261 gggtctatga tgtactaaag cgtgcaggtg gattattaga agaagcggat agcgatcgaa
    43321 tcaacttttc tgcgaagata gaagatcagc aagtcctata tatccctgct gtaggtgaag
    43381 agctgccaga acatcttgat cagttggcat cctcggaagg aaaacagcct acagcagatt
    43441 ccgagcctcc caaaataaat atcaatacag ccactccatc agaacttcag cagattcctg
    43501 ggatcggatc agtcaaagcg caagaaatca ttcgatttag agaagaaaac ggatccttcc
    43561 agaaagtgga agacctgcag gagatttctg gtatcggtga aaagacagtt gaaaaactaa
    43621 aaaacttcgt tacaattaaa tagaatgatt caaaatcgac tggcacgagc aataaatgga
    43681 cgctaatgga tactaagaat aatccaattc taagagcttg gcaggacgag gaggtagtat
    43741 ttttggatag gaaatagctt gattgttcgc aaagaaacat taaaaaaacc aatgctgaat
    43801 gtctatctcc aaaataaaat atctgggatt catattatga atacggctgt cagcggcaat
    43861 aacagtcaag ctctacgaga acgctttgcc aaagatgtac ttagctatac agcagataaa
    43921 gtatttattc tcattgggac gaatgatcta gcagagcata aacaactttc taaagaaacg
    43981 taccaaaaaa tctgcagtgg atgatagttc agctgaaaaa agactatagt tctgatcatg
    44041 ctttctttat cacgccacca gcagtcgatg agacaaaaca aaaatatcgg aataacaagt
    44101 tgatcaaaga atatatctct gttctcacag aagtagcaaa acgccatgat tgtgaagtat
    44161 cgatttttat acggaatttc ttgaacaaat ggattcgaag aatttttata atgggctaat
    44221 ggatgacgga cttcatttcg gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg
    44281 ttatatttaa agaatatttt gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg
    44341 gaggaatata aaacatgtta gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag
    44401 ttactgataa gtcacataat gaacgcattc cttgggacca gtactttatg gctcaggcag
    44461 tactgttatc tttacgtagt acgtgtacac gtttagaagt aggagcgaca ctcgttcgag
    44521 aaaaaaggat cattgctggc ggctataatg gagcagtcag tggagatgtc cactgcatag
    44581 atgaagggtg ttacgtcgtg gatggacact gcttgcgaac gatccatgca gagatgaatg
    44641 cactcctaca gtgtgcaaaa cttggtatcc cgacggaagg ttcagaaatc tatgtcacac
    44701 attttccatg tttggcctgt acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt
    44761 atctccatga ctatcgaaat gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat
    44821 ctgtacacca agttgcttta gactcacagc atttttcaaa acttcaaaat gaattaacag
    44881 gaaaacatgt ctagcgtttt agaaaggcat gttcgaaatc ggttgatttt tccggcaatt
    44941 acgtcgatga ttatctgttt gttgtattac actgacaatt ggggttatcg tttgcttctt
    45001 gccggaattt ttttatggtt ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt
    45061 ttgtgtagca taacggtatc catttcttat aggctacaag agtattcatt tttagaggaa
    45121 aaaacaacat ctgcgcaaat tactgtattt acagatacga ttcgtgcaaa tggtaatttt
    45181 ttgacaatgg aaggaaggtt atcagagaat aaacaaaagc tccagctttc ttatcaagta
    45241 aacacagaag cagaattgaa aacatggctt aacttccgag gaaagggaat agaattgact
    45301 gctgaaggcg agttcatctc tccagcaaaa aagcggaatc tttataattt tgaccaagaa
    45361 gcttacttca ggaaccatag aatttctgga cggttccaaa ttcaaaagat tgaacagatc
    45421 accatgcaaa atcactggcg aaactggctt cagagaaaaa gaggatcttt tatctccttt
    45481 gtccaatctg aatttccgca aaaaacaagt gtatatatta attctttatt atggggctat
    45541 aaagatgcag gattcagaga accagaagaa atttttaggg agagtggttt gctgcatctg
    45601 ttcagtctat cgggtctaca catccaattt tatttagggt ggctgtatta tttgtttcga
    45661 cgtatcggat ggccactaca cgtcagtatt attccgttga gtctactaac tatctgttat
    45721 gtttctattg caggaagttc tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga
    45781 ttgctagtca aattgctgaa taagcattat tccaccatgg acttatttgc agttgtcttt
    45841 tggcttcttt tactatttga tcctcgattt ctttttcatg cgggtggaca gcttagtttt
    45901 ttcatgagtt ttttgtttat cctgatttct tttgatggag attggttgaa aaaaacggcc
    45961 tctcacgtcc tgtttactat gatcacgatg ccgttgattg tatggcattt ttatgagtgg
    46021 cctattttag gtagtctttt tacattactg attgcaccgg tattcaagtt tctttttctt
    46081 cctggtgtgt tatttctcac actcttcaat cgctggctgc cggaaacttt acttttgctg
    46141 atagaagagg gattaatctt atttgagcga ataatcgatt tttcttcagg gtcgtctctc
    46201 attataggac gtttgcccct tgtgctatct gggatgtata ttttcggatt actgatttgt
    46261 atggataggt tgaaagaaca acctgtgaaa cacttgtttt atgttggtct tttttctttt
    46321 atttttttga ctttgccatt tttacgcttt tcttcaacga tcgcttttat cgatgtcggt
    46381 caaggagaca gtatcttttt gcaaagtcct tttcgaaaag aaacgatttt gatcgatact
    46441 ggaggtcagt tacactttga aagagaaaag tgggcgcaag gtatgatacg tcctcctgct
    46501 gaaagaaata tcgttccata tctaaaaggt caggggataa gtgtaatcga taaactcatc
    46561 ttgacacacg acgatacgga tcatgtggga gaattaccca cgttatctca gcattttact
    46621 atcaaaaaaa tttatatcgg ttggggcgct ggacgaaatg agccattaca aaggcattta
    46681 tctgaagctc aaaaaaatgg tactgagatc attgaaatca aacatgggga caggatcagc
    46741 ggttattatg atctttatgt attgactcct tttgaaaagg gagagggaag aaatgaagat
    46801 tcgattggtc tatggatgga atataacaat aggcgctttt tatttttagg agatttgaat
    46861 caagcaatgg aaaaacaatt gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa
    46921 ttaggtcatc acggtagccg tacgtcaagt aacacagatt ttctttccca tattgaagca
    46981 aaacatggga ttatatcctg cggcgtaaat aatcgttatg gtcacccgca cagcgaagta
    47041 ttggagacac tagaagaaaa tcagataaaa acatggcgaa cggatcaaca aggaatgatc
    47101 acctatcgct ggcatccagt ttttcatcct catgggctag tggaaacaat gatagactag
    47161 taattctcat ctgctcatgg taggataatt tttgaaagtg gtgagtaatt tgagtataca
    47221 agcagagtta caaaaaatac gtaaagaaaa acttgcatct tgttacttga ttttaggaac
    47281 agaaaagttt ctccaagatc aagttcggac agaaattgtc aaaaaaatcc aattagaggg
    47341 cgaagatgac ttaaattttt taagttttga catggaaaat gcaagtttag atgaggtagt
    47401 agctgaagca gagacgttgc cgtttttcgg agatcaacgg ttagtattcg tagagaatcc
    47461 ttatttttta acaggtgaaa aagtaaacaa tggaatcgaa caaaatactg atttattgac
    47521 ggcttatttg aaagaaccat tagaatcgac tgtattagta ttctttgcgc catatgaaaa
    47581 gttggatgaa cggaaaaaag taacgaaaca attgaaaaaa acagcaatta tcatcaatgt
    47641 ccaacagttg aatgaaaaag aagtacgtca atatctgatg aataccttag agaattcctc
    47701 aatcaaaatg gaacgaagtg caattgattt attcttgagg ttgaccgact tagatttatc
    47761 caaaatgatg agagagttac agaaattggt cctttatgga caaaatcaac agcaaatcac
    47821 ggtaagagaa gtagaagaat tagttcctaa aacgttagaa cataatattt ttgacatgac
    47881 ccaatatatt ttaaaaggga agacggaaca agctttgcgt ttatacgaag atttagttat
    47941 gcaaggggaa gaaacaatca aaattaatgc gattttgctt tctcaattac gtttattttt
    48001 acagacaaaa tttcttgtaa agattggtta tcagcaggca aatattgctg aaacattgaa
    48061 aatccatcca tatcgtgtaa aacttgccat gcaggaagta aaaaaattcg atgaacattt
    48121 gctggtacag ttgtttgatc aattagttga gatggattat caaatcaaaa cgggacaaat
    48181 cgaaaaagaa ttaagttttc aactattcgt tttgcgcaca gggcagttgt taagaaatcg
    48241 ataagaagaa agacgagggc aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg
    48301 acaaataaaa aaatcggccg aagccgattc ttttatttag cgattttttt gcttaaacga
    48361 gatttgtcgc ggttagcttt gtttttgtgg attagacctt ttgattcagc catatcaata
    48421 gctttaacag cttctttata taacgcatct acgttgtcag cacctgaagc tacagcatct
    48481 tcaaattttt tgattgcagt acgcatagcg cttgtttgag atgaattttt cacattagcg
    48541 ttttcgcttg tacgaacacg tttgattgca gattcaatgt ttggcattag tttcacctcc
    48601 gataacttaa gttcttacgc gtgttaccgc ataattcaac attcattatt atacctaaag
    48661 gcagcgtgct ttgcaatatg aacatgacaa gtttttttcc ttaacagtct tttattagga
    48721 ttttttttca gtaaaaacgg atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg
    48781 gaggcaatag cgtcaaacca aactagattt ttatttatct atttaaacaa agtttgaatg
    48841 ggaatgtttg gtactaagtt attatataac aaagagaacc gtttgcaaag ttttttttga
    48901 aaagggatac gattccctgt tgttctttgt ttttctatta agaaactgca gttattttat
    48961 aaccagtatc ctttgatcag taaaggctat tctggtgtac cgattatttt aatgtattca
    49021 tcgatatttt ttatcaacat tttttttatg accaactggt tccgacggtt ccatttgcca
    49081 cttacttcca gcacatattt atttaggggc aaacgtaaga tatattttgc caaatagcga
    49141 tctttaagca ggccattgat cacacggtcc tcaagctgca agttgatccc agtcagcatc
    49201 attggctgtt cttgtaaaac gtacgtatca attaaaagac cttcaaaagt ttccacaagc
    49261 gtcttccttt cttttcaaag taacctgaaa acaggcacta attcttccat tttgatattc
    49321 gttgaagtgg atgcgatcat tctttctttt gtccactgta atctagtata acaaaaaaga
    49381 gcagaagagc caaaaagaaa aaagagcatc gaattctata ggaagtctca ttggcacggc
    49441 ctaaattatt acaaaacatt gattaaaaaa agcccctgca tcgcaggagc atcccctata
    49501 tcgttttaat aggtcaatca aaaagcagta tcaaacacat tttgtatcaa atcaggaaat
    49561 aatagataag ctaagcccag aatcaaaagt accgctagaa gaaaccagcc gattgttcct
    49621 atgaaatact ttaatttttc gaacattgta tcacctcgtt gtcagtatat cacggatcag
    49681 taaattgggg gtgttaagaa tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc
    49741 aaatacttgt aagatacagt aagtgatacc agaagcaatg accggtccgg cggcgattcc
    49801 tcttaagaag acaacaccta aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc
    49861 agaagcaatc aatcctacac ccttggaaga taagacagcc actagcccac cgcaaaaaac
    49921 agctacccag ccaatagggg atttaaaggc ttctaataga tcacgtagac cgatttctcc
    49981 tgttgcgata gggattagaa tagccgctgt gatgatcgtc accccaatat tgattccttt
    50041 gccttgaagc caagggaaaa aggaacggga ggctggtatg agcttcataa tcaaaacaaa
    50101 agctgccgct atcatcagac tttgattttt agctaaaatt gctacaagta aaataattcc
    50161 taaaaaaagc caactttcca tgaaatatat tcctcacttt cttcgaaaca atcataacat
    50221 gtttttagaa agttacaaaa gtaggaattc atccttcaag acctattcat aagctgtttt
    50281 tttcataaaa taaacaaaat cataaaaaaa cactttgctt atttgacaga agacagccgc
    50341 gctttgtata gtggacaaga cttacatttt tttgaagaat cagaaagatc aggtaaaggt
    50401 cttagtaaac gcaagccatt cagaataacc aatattgtgc ttccttcgtg tcctacaact
    50461 ccaagaggta gatttaaaaa ttgcaggaag ttagaagcaa tcaacaagag aataacaaga
    50521 atcgaaaaaa taatattttg tttgatgatc cgccgcattt ttaaagatag ccgatgactg
    50581 tagacaaatt tatttaagtc gcttttcatt aagacgatgt ctgcgatatc catagcggca
    50641 tctgtccctt gccccatagc gacacctaaa gaagcggctg ctaaagcagg cgcatcattg
    50701 actccatcac caaccatcgc atttacttgg taaagttcat tctctttttt gactagttgt
    50761 gttttttctt ccggagtaca gcttgcatag taatgttcaa tccctacttg ttcagcaatg
    50821 gcctttgctg tgccagaatg gtcgccggtt atcatacttg tatggatgtt ttgggattta
    50881 aagtaggaaa ttacttgttg ggtatttgct tttggaatat ctagcagacc taaaacagca
    50941 attaactgct gatctttaga aagataaatc acggttttgc cttgattttc caaacgttcg
    51001 atcatttccg caatctcttt gctgattatc atcgtctcag gatcatatgc gtgcttgcca
    51061 actttccatt gcgcacctaa ataggtagtt tgtaatccaa aaccagtaat ttcttctatt
    51121 ggtaagtatt ggatttcttc aggtattgtg caatcgaaat attgcaaaat cgcatgagca
    51181 agtggatgcg tcgttttttg ttccatagca acaagaagtt gttgtgccaa atccttttca
    51241 tcaaagaaaa agctgtcagt tacaactggt tttcctttag tgagcgttcc tgttttatca
    51301 aaggcaatcg cttttaattc agaaagcttt tctaaatgga taccgccttt gattaaaatc
    51361 ccattttttg cagaatttga aagagcagct agagaagctg gtgtagcaga tgcgacaagc
    51421 gcacaaggag aagccacaac taataatacc attcctcgat aaaagctttc atcccaactc
    51481 caacctagga aaaagtgggg gagaaggatc attagaggaa cagcaagcaa aatcaatttt
    51541 acataattat tttcgattcg ttcgataaat gaagctgttt gagttggcgt attctgcgct
    51601 tcttctacta attggataat cttagcaaag acagtttcgg aactcgtttt tgttactcga
    51661 atcgtgatgg gatttccttg attcagcgtt cctgcataca tctcatcgcc taaatatttt
    51721 tctacaggca cagattcacc gcttaatgca gactcatcga tcgttgcctg tgtgctttct
    51781 aaaaagccat ctatcggaac agctgctcct ttagcgacaa ataccaagtt atccaccttt
    51841 agttgagaaa catctacttc ttgcatttgt ccattttctt ttaataattg ggctttttgt
    51901 ggttgaagat tcatcaaagc agtaatttct ttttgacttt tattagttgt gtattcctct
    51961 aatgcaccgc ttaaacaaaa gatgaatgtc aacattgctc cttcaaagta attaccgatc
    52021 aaacaggcac caatagcagc taaagccatc aataaatcca cattcagtgt ccgatcattc
    52081 cacaattctt tcaagccttc cgatgtttgt ttatatccac cgatgataat ggcactgata
    52141 taaaaaagtg gggtgatggt aagagagaat cggtcgaaga taaaaccgaa gatcataaat
    52201 aaaaggcagc cgattgttgc tgcaaaagct tttttctgat tagtcatcgt tattagacct
    52261 ccttgtcaaa acaaggatag cataataaaa atgtaattga taataataac agctaaatga
    52321 gaacgataat ggttatcatt tggtgattaa gcttgatgtt gtttttatta tttataatga
    52381 ttattattaa agaaaataaa aaaccagaac atttctcaaa taagagaagt gttctggttt
    52441 tttctacatt gcaataaacc aataaccaat caaaatgata ccaaggataa tacgatacca
    52501 gccaaaagcg gtaaagtcgt ttttcttcaa atagcttagt aagaatttga tagctaagac
    52561 ggaaaccaca aaagatacga atgttcctac aagaagaaca acagtttctt ccattttgaa
    52621 tgaattccct tcagctaaat atttgacgat cttcaagccg cttgcgccaa acatgacagg
    52681 aatccctaag aaaaatgaaa actctgtagc gacaaaacgc gaagcaccaa tcaagataga
    52741 tcctaggatc gttgcgccag aacgggatgt tccgggaaca agtgccaaga cttggaataa
    52801 cccaacaaga agagctgctt ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt
    52861 gtttttgttg cgtttttcga caataataaa ggcaataccg taaacgatca aaacaatggc
    52921 aactggtaag aacttgtgga aatttgcttc taaccaatca tccaaaggca aaccaatgat
    52981 gatggctggt atgcaagcaa cgatcacttt aaaccaaagt gtccacgtat cttttttttc
    53041 taccgttgat ttacttggag aaaatgggtt taacttgtga aaataaagaa cgacgacagc
    53101 caagatcgcc cctaattgga taacgacatt gaacatcgac ataaattgtg aactggcatc
    53161 cagtttgatg aattcatctg ctaggatcaa atgaccagta ctactgatgg gcagccattc
    53221 cgttattcct tcaataatac cgagaatcac tgctttgata atatttgcaa aaaacataaa
    53281 ttccttcctt cccaattaag atacatctta tagtataccg ttattttttg agaaacccaa
    53341 tctgtttttt aatattaaga aaaacttgag aaataaagca gataagtaca cgaagagaaa
    53401 aaagaagaca aagccctcgt tcagactttg ccttttatga ttctctggta aaaattaaaa
    53461 tatccccatt atagaaacga gtcgcgacta tgtgttttcc cgttatcgat ataagacgta
    53521 tcattgatgc cgtggataga aaatcgaccg tttgcataag tgacctttgt tacgctgcca
    53581 tttaaaagcc cagcacgaac aggctgttta ggatcgatca gattaagcaa aaaggcgatc
    53641 gtcaaaccat gagatacgac taaaacattt ccaccaccat ttttttcgca gtgatgggcg
    53701 atatcttcaa atcctgtcca tacacggtct cgcaatgttt cataagtttc cgcccaccca
    53761 gcggtatcta agttgtatac agcattagca atttgttcaa aagaaacttc tgtggtaaac
    53821 atttcatcat atgttttaaa attcaataca cgagggatca caccccacat ttccatgtca
    53881 tatccacctt caagagaccc gaaacaccat tctctaatcc ttttttcaat aaaataagga
    53941 atttcttttc ccttagaatg ttctcctaga ataatacggg cagtttcgat tgcacgacca
    54001 ctgtcactag aataagcaaa tgaaaagtcg acatttttta acccgcgacc taaataatga
    54061 atgccttctt gtccttgctt tgtgaggggt gtatcacacc agccttgtac tcgttcaatt
    54121 gtattgaaca tcgtttttcc gtgtcgtacg atataaagtg tagtttctgt cattttattc
    54181 tcctcctaag tcgttttaac gattgaaaaa aggatttgtc cttttttcct gttcaatcgt
    54241 cgttgcatcg ccatgtcctg gatagactgc aaattcatca ggtaatacaa acagctgggt
    54301 ccgaatacta tgaagtaatt gttctaaatt ccctgtatac agatcggttc taccgatact
    54361 tcctctaaac agggcgtcgc cagaaacgac aaaatcatca aaaataaagc tgacgcttcc
    54421 tatagaatgc cctggggtag ggacgacgcg aaaagacatg tttcctaaag tataagtttt
    54481 catttcaaat tcatattctg caggcgagac aataacatca gcaatatcat catgtctacc
    54541 gagtccagaa agattcaaaa tcggatcacc tagccatttt tgctctagtg ggctgacata
    54601 aactgggatt tgataatacg cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt
    54661 atgggtaagc aaaatcgcta ccggctgttg gtttgttttt ttgatttctt gtttgattcg
    54721 ttccgcatct tctccagggt caatgatcaa aagtgcttct tcgttgtaga ccaaataaca
    54781 gttttcttca atcattcctg tttttaatct ttcgatatgc atgtgcattc ctccttgata
    54841 gccaaaactt ctttcatcca ttagtataac gcattcattg ctaggaaaca aaaacaggta
    54901 cttatttctc tttacttatc tgaattatca gactatatga aaagtatttg gatattctaa
    54961 agagaaggaa agtaagtttt catagcattt taatatgtcc ttgttacatt agattcatcc
    55021 aaaaatccaa attctatatc ctatatccct gcctaatcag cagggtgttt ttttatgttt
    55081 ggaaagagag ctctttttgc taaactaggt tttttcaggt aatcttagag agaaagaggt
    55141 ggtggaaatg atcaaacagt caaaaatatc tgtgcggcac ttagtagaat ttattttgcg
    55201 acgtggaagt atcgacaatc gtaaaaaaag taaccatact gcattagaag gagcgagaat
    55261 ccaccgcaag ctccaaaaag atgcgggaga aaactatgaa aaagaagtct ttttaaaaac
    55321 aacagttcaa ttagatgaat attacctgat cgttgaaggc cgtgcagacg gtattttcaa
    55381 aagagacggt atttattata tagatgaaat caaaacctcc gaaccacgat ttgaagattt
    55441 agaaccagaa caagtggaac ttttctttca tcaagcaagg gtgtatgcct atatctatag
    55501 tcaagaacat gatttacaag aaataaatct gcaattgact tacttccaga cggcagaaga
    55561 agtgatcacg agaaaggttg aacatcagac aagagagcag ttagaaactt tttttaaaaa
    55621 gctgactgaa gattataaag aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa
    55681 tgcctctttg atggctttga aattccccca tgatgagtat aggaaaggtc agcgtgaact
    55741 agcggtagct gcttataaaa cgatccgtac gaaacagaaa ttgtttgtag aagcacctac
    55801 cggaacagga aaaacaatct ctacgttatt ccccgctttg aaagctgtag gggaagaaga
    55861 gggagaaaag atcttttatc taacggctaa aacaataact agacaagtag ctgaagatgc
    55921 tatgacagca ttaaaagata caggagctga agtaaaaagt gtcactttga cggcgaaaga
    55981 caagatctgc tttttagatg agacgacctg taatccagat cagtgcccat atgccaatgg
    56041 ttattacaat cggattaatg aaggtttatg ggatcttttg aatcatgaga atcagatcac
    56101 tcgtgaagtc atcgaaactt atgcaagaaa gcatacactt tgtcctttcg aactatcatt
    56161 agatgtcagt atctggtgtg acgtaatcat tggggattac aattatttat ttgatccaac
    56221 tgtttattta agacgttttt ttgaagatga aaaaaacgag gactatctgt ttttgattga
    56281 cgaagcacat aatttggtga atcgttcccg agagatgtat tcggcagaac tatcttatga
    56341 aaaaacgaaa cgaagtaagg aagctatacc aaaggaattc aaaaaacttc atcgccgttt
    56401 caacaaacta ttaaaagaat ttgattcgat ccgagaaata gcaaaagaag atcattggga
    56461 ttatcatcat caaaaagcac cggctgaatc tttagtaaag gcaggttatc aattaagcga
    56521 aaaaattaaa gaatggctgg cagaatttcc tgagcaccca tcacaagaac aattgcttcc
    56581 ttattatttt gatttgcttc attttttgaa ggtcagtgaa ttttatgatg atcactacga
    56641 aacaacagtc gaaaaaacgt atcgcgatct gatagtaaaa gagttttgta ttgatccaag
    56701 cttgtttctt gagcagtcgt tggataaagg aaaaagcagt attctttttt ctgctagttt
    56761 ttcaccactc tcttattatc aggaaacact ggggggacaa aaaagtctgg cttacaaact
    56821 gccgagtcct ttcccagaag gaaaccagca agttttcatc gcaaattacc tagagacgac
    56881 ttatcgaaaa agggaacaca gtctggcaaa attagtagag acgattcatg cttttgctga
    56941 tggaaaggtc gggaattatt tcgttttctt tccttcttat caatatttag atcttgcggt
    57001 ggaagcattc agacagcaat atcccgacag caatgtgcta atccaagaaa cggacatgaa
    57061 tgaggaagaa cgcgaacgat ttttaacaaa atttcaaaca aatcccgctg aaacattgat
    57121 tggattttgc gtacttggcg ggattttttc agaaggaatc gatttgagag gggaccgatt
    57181 gatcggcagt atgatcgtag gtgtaggttt gccgcagatg aatcatgagc aggaactgat
    57241 caaatcatat tatgatgaga aggaacacct tggatttgct tacgcttatc agcttcctgg
    57301 aatgaacaaa gtcttgcaag ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat
    57361 cgttgtattg gcagatcaac gattttctag tttttcttat cgacgtttat tcccacaaca
    57421 ttggcaaaca gcaagagaag tacgaagtgt tggggaattg gaagaaggaa tacagcgttt
    57481 ttggttatca aaagaagcag taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt
    57541 ttttgattaa cgatagttag tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa
    57601 agcaatcaca gcttgtagat catcacggtt cttacctgtc actctaatct gatcttcttg
    57661 gatttgtgct tttactttca gtttttcatt tttgatagct gtagtgattt tcttcgcgtt
    57721 ttcacgatcg attccgttga ccaaatcggc agtttgtcga gctttgccac ctagagcgtg
    57781 ttctgattcg gaaaaatgga tatttttgat tggcacattt cttttgatca gcttaccaaa
    57841 taatacatct ttgatctgtt cgattttgaa atcatcatcg ctcaatacaa ctagattgct
    57901 gttctctaat ttgatttcta ctgtagaatc cttgaagtca aagcgattgg acaattcttt
    57961 tgttgtttgc tgaatcgcat tttttacttc ttctgtattg acttctgata caatgtcgaa
    58021 gctagcatct tttgccatag gaaccctcct gatatacata taaatattta ccatacatct
    58081 atcttatcat aggattaggg cagattctta cctgtttgct aaaattcttc tcatttgagt
    58141 tcgaagtatt ttattttaat agataaactg ttattcttac atttggaata ccaaagtagg
    58201 ggagaggtgc ttgtgagtaa aattatgact gcgtatcata aaaatgaaag attaaagaaa
    58261 atagtggtta ttttgataac cggattgacc gctgcggtcg ctttaaatta ttttttgatt
    58321 ccagccaatg tcttttctgc agggatgaat gggatcgctc aaatcatttc ctcgctttta
    58381 tatgaatggt ttcatatcaa gatagacaca ggaacattta tttttctttt gaatatccct
    58441 gtgtttgtat tagggtttct caaagtagga aaacgagcaa cgatccttag ttttgtgaat
    58501 gttgtatgtg tatcggtgat gacgatgctg cttccagtcg gacagatcac tgataatatt
    58561 ttgatgaatg ccctagtagg cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa
    58621 atgggcttta caactggtgg gatggatatc atctctcttg tactttcaca aacaactgga
    58681 aaaacagtcg gaaactacat gctgattcta aatggtatca ttgtagtcat cgcaggcttc
    58741 ttctttaact gggaaagtgc cttgtatacg attatttcca tttatgcaat gactcaagta
    58801 attgatgcca tccacacgag tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca
    58861 gaagaggtaa cagaagaact agcaaaacgg atggtacgtg gaatgacatt actgccgtct
    58921 gtcggtggct attcaaaaaa acaagggaac atgatcatga tggtcatcac ccgctacgaa
    58981 atgtatgatc ttgatcagat cgttcatgaa atcgacgacg atgcatttat caatatttta
    59041 ccaactcatt cagtatttgg ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca
    59101 actggcgtat tgccagaaat aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt
    59161 ttagaataaa tttaatctat tacatctaat aagaacattt ttataaattt aaacgagaat
    59221 cttacttcta aattctcatt tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt
    59281 gttaaggagt gtcgtacgat gagcgaagca aaccaagaac ggtctggaca agaaatagaa
    59341 ctaatcaaag aacgtattct tgctgccttg gaaatggtga ttgatcctga attaggaatc
    59401 gacatcgtca atttaggctt gatttatgat atagaattca atcctgaaaa tggagaaaca
    59461 gtcattaaga tgactctaac aactatgggc tgtccattag cagatatttt aacagaatct
    59521 atccatgacg cattaaaaga agtgccagaa gtaacgaaag cagaagtcaa actagtctgg
    59581 tatccagcat ggacgacaga taagatgagc cgttatgcac ggattgcgtt ggggatacga
    59641 tagaaatctt ggctgactag ctatgagaag caaataggaa aaacaaaaaa gccttttatc
    59701 ctttctagaa gaaaagagat aaaaggtttc tttgtttata aaattttgtc tgctatatta
    59761 taagttaatt aaataaatgt gttctattga taaaggacat tcaaatccct ttccttttgg
    59821 aatccttctt ttttacatca gtttgatttt cgtatagtat tctttctcat cttcacgata
    59881 aatcgcagcc ccattttttt gttgtgcttt aagactgcca agattttttt tatttacaga
    59941 caaaagtgcc tcatcaatgc cgattttttt tgcctcttgt agtactaatg ctaatccttg
    60001 tgtggcatat ccttttttac gataattagg ggagatgccg taaccaatat ggccagcgcc
    60061 gtttcttaat gtttcgttca gtttatggcg caaattaaaa attcctacat actcatgttc
    60121 atcactttct aaaataaaga cggttgcggg aacgtaactc tcaggaagat cgattcctaa
    60181 agacgttttt tcgcattttt ttacataatc taaaaattca gcaaatgtat agccataagc
    60241 attgttgata aatccactct catttggtcc aaagctagtt tgtagctgat aagctttctt
    60301 taaatctgct tcccatagtt tgatcagttt catcgtattc acctctttaa gtaaccttat
    60361 tcatttgttt tctactatag cactattgtt gtaaatagcc atgcctattt ttatttattg
    60421 tgtcatatcg tattaagaat catcgaacaa tacaaatatg aattacaata aaaaaattat
    60481 ttgaagttcg ttcattcgtt acttatgatc tctagaagaa agaaaacgtg aattacttca
    60541 gcgtctagaa ttccagaagg atagtaatca acagaagaaa taatcaatat ccaaatgaaa
    60601 gaagatagct gaatcgagaa aaagaggaaa aaagaaatga agaaaaaaat aaaatagtta
    60661 ctaatcccag agtcgttcgt ttaacattga aatcgatcat atggataaaa cagatttttt
    60721 caccaaccct caatagatga tggagttgct cggatgaatt atttgtgtag atggcataag
    60781 ggagggcgta cagaaatgaa aaagaacaaa aatatgttct tgacaaaaaa cacatgtaat
    60841 cctaaactaa aagatgtgat gcggctatgg cggaattggc agacgcgcta gcttcaggcg
    60901 ctagtgaggg tgacctcgtg gaagttcgag tcttcttagc cgcataattt gtttttttat
    60961 aaagagaagg tacacctgga gcgatgagaa agaaaataac atattatcta aaagaatata
    61021 ggaaaaattt taaacaacgg aaccagattc aaataaatca aaaaaaattt gtgtgaaggt
    61081 gggacagttt aaaacctaat agattgattc aaatagtaga tttatagatt ctgatacaag
    61141 aaatactggc aaacgatagt taaggaataa agactaaact taaactcaaa aagaggtcat
    61201 gcgaaagaat aaatcgcatg acctcttact atattttgaa tgtgtttaaa cgttcaaata
    61261 atgaatctta gtaccaaccg tttgcttccc agaatgcttt cgccgcttcc caagaaccat
    61321 aacgtgaagt aacatattgt tctgctactc tttcttggtt tgcagcagag tagtcaccat
    61381 ttaagtaaga agaatctaat tggtaacggc cgatgtaacg tccgttcgtt gctgtgtaag
    61441 aaccgcttga ttctttttgt gcgatccatt cttttgcaga gcttgtactt gctggagtag
    61501 cagcagtttc tgttacagca ggagcaggtt gtgtttcagc aacaggcgct gcttgtgttt
    61561 ccgtttgaac cgtttcttgt acaacaggtt gttcagcttg aacaggttca gcttggactg
    61621 gtgcttcttg aacggctgct tgaggttcag cagctgcttg tgcagagcct tctgttggga
    61681 ttgttaattg ttgtcctgag tagatcaggt taatatcaga aattgaattt gattctgcaa
    61741 tggcattgat caaggagtta tcaccaacgt atttttgaga aatcgttgat agagtatcac
    61801 ctgattgaac ggtataagct tcgtccgcat gagcagtcgt tcccatgaag aatgcagcgc
    61861 cggcagccaa agttgttcca aaaagtaaag ttttaagtga tgtcatgaaa aatctccttt
    61921 attcgttaaa aagttttatt tgttgtgttc aacgaggaat actttaacac gtgaaaatat
    61981 ttcataggta aaagaagcat gacaatttat gacaaatcca cgttttttgt aacagaatga
    62041 tgttcgctcg atgtgaaaaa tgatgaggaa tttcacataa tgcagaaata atgggattag
    62101 aacaggtgtt ctgatgagaa aagaaatgta taaataactt gaaagaaatt gcttttgttc
    62161 atcattttat ttacatattg cgtatatttt ttgtattttt gcttgagatg ttacaataaa
    62221 agaaaaagga ggcggttcca atgagtaaaa gataccagaa catcatggta gcagttgacg
    62281 gatcaagaca atcgatcaaa gcgttcgctg aagcccttga cttagcaaag gacaatgaag
    62341 cccacttatt tatcgtgtca atcatcaaca aagttgagct gacccatagt gcctatgcct
    62401 tttcaaaaat ctatgcagat gaaaaacaaa gaacagaagt agccatgctg aaaaaaatca
    62461 atgatgccaa agagtacggc attgctgaga tccacgcaat agttgaaact ggagatccaa
    62521 gaaatttgat tgccaatgtc atccctggac aagaaaatat tgatttgatc gttatgggag
    62581 cgacaggaaa aggtgctata caacaagcat tagttggatc gaccgcttct tatgtcgtat
    62641 cacatgcccc ttgcagtgtg ttggtcgtga agtaatgaga taagggagga atagaaaatg
    62701 gttcgtcctc aagaagtccg tgcgccaaaa gaaaaaatag aaattttagc aattattgaa
    62761 gacggcacac aaacaaagaa gggatactcg atcgctttag taaagtggaa aggaaaaaaa
    62821 ggtgttgctc tgagatggga tggagataac caacaagata aaggattccc tgtcacagct
    62881 aacggttatc atccagcgtg gtttgttctg cctgataaat ttatggaatt atacagctat
    62941 gattatgcaa gagccgcagc atcaatcaaa gcattagata aattaacaga agagcagaat
    63001 gaaatggagg aaaaataaaa aagacgaacc aatcagcctt tagaaaactg attagttcga
    63061 ggagtaaaaa tgaaaaaagg ttatttggga tgaaactaga ataatgcgta taacttaaat
    63121 aaaacttaaa gcaataaaat ggcaagaggg tgaggcaaat ggaagcagga aaagtattac
    63181 aggaagtaaa agcactatgt gcagataaaa aatatgaaga agcgaaaagc ctgatcgaaa
    63241 agaacaaaga aaatttggaa gaaaagtacc cgatcgcaca agaatttata gaattaaaac
    63301 aaggaacgat ccttcaccga ttcaaacatt tttttggtat aacagaatag aaaaaacgat
    63361 taaagatcgg cagaaatttg ctgcatcttt aatcgttttc tttttaaaca tgcgagggat
    63421 tcaattctga ttcttatata aaaaatagat ccaaataata agaaaaatta ctgaaagcgt
    63481 caattcgatg atgtgtgtta ttaatacaga cgttgtttcc caatgcctaa aagaaaaaat
    63541 ttgataagta aaatatacag caggtaaaga ggccagtaaa actgaaaact tcttttttgt
    63601 ccattttatg taatagaaaa gaatgcttat cataataaaa aaaggaatat aaaaaacaaa
    63661 ttgaccgatc gcgatcatac tattgcctcc gataaataaa gtccatgata caaaataaca
    63721 ctttgtgcga aatggcgcaa gcagttttgt ggatttatcc ggtaaaatct gtatcgattt
    63781 tgaaattaga ggagaaactt gctataatca aagtgaaaga aggagtggga ttttcatgga
    63841 tcatgtagtg ttagaaatcg atttgcattt gatcaataat attcgggtga tttactatgt
    63901 tgtaagtaac agtgtcgaac aacgtgtact gacgaataaa ataaatggta ttttagcaaa
    63961 gaaagacgtt caccgattca ataatggtga aggaagttat tatagtatcc cagtagaaaa
    64021 aattatttat acgacagtca aagtcagaga agatctagat accaaaaaag catatgaacc
    64081 tatttttaca acttattgat tgacagcaga tggaggaaaa aaatgaatcc atatgaacaa
    64141 cttattcaag atttgatcga tggaaaaatc gaaaagattg atgtaaaaag agaagaatta
    64201 atggcttttc gagaagcgtg gctgaagttg gagaatcgta aatatgtggt gggaaaagcc
    64261 tcactgaacg gcaatgtgac ttatcattac gatccgacac gtttatttta gtatgaagta
    64321 ttcagaaaag aaccaaagga ggacgatgca gcagcattgt cctcctttga ttttacaaaa
    64381 gtgaaagttt tacttatttg aatagatttt taaatttgtt tttgacactg tcgatattta
    64441 catcttttaa aagattttgg gctttctctt tataaggtcc taattgttct ttatgttctt
    64501 cgataaatcg ttttgcgcca tcgaaattgc cgttcttaat catttccttg actttttgaa
    64561 ataattcttc ttgattcatt ttgaacacat cctttgctat caacatgatt ttttacatgg
    64621 acaaaacgag aaaaactgat ttatccacac gtcaataata tcaaataacg atcattttta
    64681 ctaaaaaaac actcgattct cgcttctaaa gtaggagaaa aatctccaac ttgggacgga
    64741 tggaatttct ttaactgacc catatactga atatataaca aggaggtaga aagatgaaag
    64801 tgattaaata tttgattgga ctggcggcga ttagtggtat tttgctattt ggactgaaat
    64861 attatactga aggaagttat ggagaaatcc ctggtatact tgatcagcta aatccattag
    64921 ttgaaaaagg agaggtctat gtaaagacac aaaaaccaga ggaagtaaat gaatatggta
    64981 cagcaaggta tgtgcagaaa gctgctgatg ccaatgggaa agaacgaacg gttgaattta
    65041 atggtctttc tgtgttaaaa gaaaatcatt atttgaaaat tagcaataaa ggagcacaca
    65101 tagaaacgta tgaggaagtt cctagagaaa aagttccgga gaaagcatta gcaattattg
    65161 ggtaaatcag tttttgtatt aagaatacgc ccgattttat tattcataat ttaattatgt
    65221 aaactaaata caagtagtaa aaataataca ataatccccc tgcaaaaaga ttgttctttt
    65281 acagggggtt cattttttca gcaagcacat caaattggga tggcagggtt cgaacctaca
    65341 attgcttgat tcagagtcaa gtgccttacc agtttggcta catcccattt attcaacaaa
    65401 ataatcatag cactttccta aaaaaacgca agttattttt cttgatcgga tagttgttgc
    65461 tttactcgta aaaggcggcg tactagtttc ttttctaatc cagcaggaag ggcaatcagt
    65521 tctgctactg acaagacggt gtccaataac tgatattctt tgacaggttc attcataata
    65581 tgatagatgt ttgctaaacg ttcaatatat tcaaagcgag tatactctgt tcgagcaatt
    65641 agaaatttca ataaatcggt ggctttctcg tactcttgat ctgcgtaata aacaagagat
    65701 tgacgataca atttgatttc cagttcattg agggtagcag gtctgcgacg ctcgttccac
    65761 tcattaatag agactttacc ttgaacattt cccttgcagt cacggacaaa aataatcgga
    65821 atttcatttg gatccatttt tttatgtgtg aatttttcca ttatctacgc tcccttcaaa
    65881 ggtttggtat cttgagtata agggattttt gtttgaatta ctagcttttc tccaaagtta
    65941 gcatctgtcc acccattgca gtgaaaatcg ccgaaaaatc gttgatcggt actgctcgat
    66001 tttttacacc atagggatcg ttgacataaa tattttcttt gtcatatcca gtgactacac
    66061 aagcatgaac aagaggagtg actcttactt ctccattatt tgtggtccaa gtcataaaat
    66121 cagtttcatc tgggacttca aaattgatag tcacagaagt ccagacagga tttcctttag
    66181 atagtgcttt tttgatatca tcgagttgag catcggtttt tggaaaagtg tgataatccg
    66241 tttggacgat ttgctgagca agggaggcaa ctgggggaac atagacgacc atagcccagt
    66301 ctccgccact gatatcacca acaaatcctt cattaggatc gccatgagtc ccatctgcat
    66361 tgaaaacagg gacgtaatcc aattgctcag ctaactggtt tttagttgtt tcataaccat
    66421 aaaaagataa aagcatagaa agcgaagtga cttcacagcc attttctaaa gaaggagaat
    66481 caaactggct ctctaatgga acatctagta aaacttctgc tttctctttt gtctttttcg
    66541 ttttttgtgt tgaacttttt tgtgcagtgt tcattgtatg ttctggagaa tggatatgta
    66601 ggtaataact tgtaccgctt aataaaagag cagctgtgcc ccctagaaac aatagttttt
    66661 tgaacgtttt tttcttcatt tgaaatctcc cttttcagct gtttatcttt cctattataa
    66721 atgtattttt attggaaatg gaagtattat attttaatat gtaggaaata attagttttt
    66781 aaggaatatg ttttaatttt ttgaaaaaaa ttcttctaaa tacaacagct gttttaattg
    66841 tgaaaacgaa aacagtacgc tataatgcct gtaaggttga tttttaactg taaataaaaa
    66901 tcaatgagtt aaatctccaa agaaatagca gtggtaatgt ggagaaaagt tccagcagtt
    66961 taggaggatt ttgatgacgg aagaaatgat taatttagga gaacaatatg catgcaaacc
    67021 aattggtttt acaaaaacgg tcattggtga agttgtatca aaaatgacaa actgcgccgt
    67081 ggtcaaagtt gcccaatgtg ctgcagagga ccaagaatta ttagatgaaa aagcaagcat
    67141 ggttgttgca aaatatgata catttgaata aagaaaacaa ttggacgtgc ggcgtgctgc
    67201 aagtccaatt tctttgagaa ggtaaatcag tattcttttc ctattttctg gagaagaaaa
    67261 agcgaggcga gttgtcatgg taacattctt tacggttcta ttgtttttat tcgttgttgt
    67321 gatgttttta tttctttggc tggttcgaaa agaaattatt tatcggactg tgcgaaatcg
    67381 atgggtctac ttggtgatac ccttcttagt gtcactagtc atttggtata cactcatcag
    67441 tcatcctaca gcagatgaat tggcaaaagg gatcttgtca gcaatgattt ttattagttt
    67501 tttgttggac agtagaggaa tcacagaaga aggacttgtt ttgaatagct ttgacaaaaa
    67561 aggtgttcct ttttctgaga tcaataaaat tgtattatat cagccaaaag gttctaaaat
    67621 cgtaaaaatg aattttttcc gaaacggatg gcgaggaccg atgctgaaat tttctgcatc
    67681 attagaagaa ttagttccat ttttgtccca acgcttaaac gatgaggcag agattgatat
    67741 tatgattgat ccagaataaa aacagaggtt gcgacaagat gtttgtcaca acctctgttt
    67801 tttatttcaa ataaaattat ccaaatacgc ggaagcgatc ggcatcgttc atgtattctt
    67861 tttcctcagc cggtgtttct ggtgaaccga atactaattg cgaacgtagt ttccagtttg
    67921 aagggatatt ccattctttt gcaactgctt cgtcaataac tgggttgtaa tgttgcaagt
    67981 ttgcgcccaa tcctttatca actaatgcta cccaagtatt agctgttgcg attccgtttg
    68041 attgttctga ccaatctggg aagttgtctg catataattc aaattgttct tgtagacctt
    68101 ttaccacgtc agtatctttg aagaataata ctgtaccata accatttttg aaaccagcta
    68161 atttgttttg tgtatttggg aaagcttctg ctggagtcaa tgggcgaagt gcttcttcag
    68221 tgatttccca aagtttttca tgtgcatctc cgaaaaggat aactgcgcgt gttgattgag
    68281 cattgaaagc agttgggctt tctttaattg cttctttgat caaagttgtt aattcttcat
    68341 tagaaagtga aacattacgt cctagatgat agattgaacg gcggtttttc aaagtgtcag
    68401 taaaagttgt cataataaaa tttctccttt gatttgcgtt ttgcattttt ttaattgatt
    68461 acgaaatgaa gtatagcacc ttacaaaaag taagtaaaca gatatgctca caaaaaataa
    68521 gcgaagttca aaaaacaatt ttaataagaa aaatcgttat gtaaggattt tcttagttat
    68581 cgctttcatt gttgtgtttt aggaattttt gcttatttga aaaaaacagc tgatatataa
    68641 ttattaaatc tctatcttct tttttttatg atattgccat taaaaattac ttgcttttat
    68701 agaaaattag tttatatttc ttaaataagt tttttagtta aatttttcgg taaagatgta
    68761 taatattttc tgaaaattta aagaattggg gtatagatta tggaaaaaca gcaagacaag
    68821 ggcttcttcg ggcagccgaa gggattgtca actttgttct tcactgagat gtgggaacga
    68881 tttagttatt acggtatgcg tgcattactt atctattata tgtacgatac agttgccaac
    68941 gggggacttg gattaccacg agcaacagca ttagctatca tgtcgatcta cggatctttg
    69001 atctacatgt ctagtatcgt cggcggatgg gtatctgacc gagtgttagg agcaaaacgc
    69061 actgtattct tcggtggagt tttcattatg cttggccaca tcgtcttggc tttaccattt
    69121 ggtgtaagta cattgtttgt ttcgatggca ttgattatta tcggaaccgc ctttttgaaa
    69181 ccaaatgttt ctggcatggt cggacatctt tattcaaaga ctgacttgcg aagagatgca
    69241 ggattttcga ttttttacat gggtgtcaac ttaggggcat tattagcacc actaatcgtt
    69301 ggtacaatcg gtcaagaata taactatcat ttagggttct ctttagctgc tattgggatg
    69361 ttctttggat tattacaata catcatccaa ggacgcaaga cattagacgg agtgggtaca
    69421 acaccgccga atcctttgac aactgaagaa cgtaaaggat tcatccgtaa cttgatcatc
    69481 gcacttgttg ttatcgctgc agtattcggc ggggcacaac taactggtca tctgacaatt
    69541 gacttttttg tcaatacaat cagtgtattg gggattatct taccgttgta ttactttatc
    69601 aaaatgctga cttcaaaaga tgtaactgct gaagaaaaac caagagtatg ggcttatatc
    69661 ccattattcc ttgcagcaat cattttctgg tcattacaag aacaaggttc atctatctta
    69721 gctttatttg ctagtgaacg tacacaatct acgctatttg gtgtaacgat ccaagcaagc
    69781 tggtatcaat cattgaatcc aattttcatc tttattctga caccagtatt cgtaacgatg
    69841 tggacgaaac ttggtgaacg tcaaccatct acagtagtga aattctctct tggactttta
    69901 tttgcaggat tatcgtactt gctattgatg ttgccgggta tgctttatgg tacaagtgga
    69961 aaagtaagtc cattgtggtt gttgggaagt ttcttcatcg tggttattgc tgaattgtgt
    70021 ctttcaccag ttggtttgtc tgtgacaaca aaattagcac cacgagcatt tgaatcacaa
    70081 acaatcgcta tttggttctt agctgatgct tcttcacaag caatcaatgc acaaattgca
    70141 cgcttctaca caccgggaac agaatctgct tacttcggta ttatcggtgc agtagcaatc
    70201 gtcggtggta tcttgctatt tactgtgaaa gaaccaatca aaaaactaat gggctctatt
    70261 cattaatcaa tgaacataaa aacaggaatt gcttatttgc agcagttcct gt
//
LOCUS       DADVXE010000008        64888 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.008, whole genome shotgun sequence.
ACCESSION   DADVXE010000008 DADVXE010000000
VERSION     DADVXE010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 64888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.008"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..1422)
                     /locus_tag="KB913_000538"
     CDS             complement(<1..1422)
                     /locus_tag="KB913_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBB6818925.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGN"
     gene            1674..2855
                     /locus_tag="KB913_000539"
     CDS             1674..2855
                     /locus_tag="KB913_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6818926.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(2915..4543)
                     /gene="treC"
                     /locus_tag="KB913_000540"
     CDS             complement(2915..4543)
                     /gene="treC"
                     /locus_tag="KB913_000540"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBB6818927.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(4994..7705)
                     /locus_tag="KB913_000541"
     CDS             complement(4994..7705)
                     /locus_tag="KB913_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6818928.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(7715..8416)
                     /locus_tag="KB913_000542"
     CDS             complement(7715..8416)
                     /locus_tag="KB913_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6818929.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            8602..9201
                     /locus_tag="KB913_000543"
     CDS             8602..9201
                     /locus_tag="KB913_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6818930.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            9282..10295
                     /locus_tag="KB913_000544"
     CDS             9282..10295
                     /locus_tag="KB913_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBB6818931.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            10403..11320
                     /gene="rbsK"
                     /locus_tag="KB913_000545"
     CDS             10403..11320
                     /gene="rbsK"
                     /locus_tag="KB913_000545"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBB6818932.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            11348..11743
                     /gene="rbsD"
                     /locus_tag="KB913_000546"
     CDS             11348..11743
                     /gene="rbsD"
                     /locus_tag="KB913_000546"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBB6818933.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            11743..13116
                     /locus_tag="KB913_000547"
     CDS             11743..13116
                     /locus_tag="KB913_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6818934.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            13473..15617
                     /locus_tag="KB913_000548"
     CDS             13473..15617
                     /locus_tag="KB913_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6818935.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLRLDKSFWLDLPLKK"
     gene            complement(15669..16709)
                     /locus_tag="KB913_000549"
     CDS             complement(15669..16709)
                     /locus_tag="KB913_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6818936.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(16986..18788)
                     /locus_tag="KB913_000550"
     CDS             complement(16986..18788)
                     /locus_tag="KB913_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6818937.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(18802..19554)
                     /locus_tag="KB913_000551"
     CDS             complement(18802..19554)
                     /locus_tag="KB913_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6818938.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(19563..19925)
                     /locus_tag="KB913_000552"
     CDS             complement(19563..19925)
                     /locus_tag="KB913_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6818939.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(20101..20973)
                     /locus_tag="KB913_000553"
     CDS             complement(20101..20973)
                     /locus_tag="KB913_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBB6818940.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(21024..21512)
                     /locus_tag="KB913_000554"
     CDS             complement(21024..21512)
                     /locus_tag="KB913_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBB6818941.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(21650..22441)
                     /locus_tag="KB913_000555"
     CDS             complement(21650..22441)
                     /locus_tag="KB913_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBB6818942.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(22496..23104)
                     /locus_tag="KB913_000556"
     CDS             complement(22496..23104)
                     /locus_tag="KB913_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBB6818943.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(23097..23414)
                     /locus_tag="KB913_000557"
     CDS             complement(23097..23414)
                     /locus_tag="KB913_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6818944.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(23570..24298)
                     /locus_tag="KB913_000558"
     CDS             complement(23570..24298)
                     /locus_tag="KB913_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBB6818945.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            24457..25338
                     /locus_tag="KB913_000559"
     CDS             24457..25338
                     /locus_tag="KB913_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6818946.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(25575..26618)
                     /locus_tag="KB913_000560"
     CDS             complement(25575..26618)
                     /locus_tag="KB913_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6818947.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(26621..27289)
                     /locus_tag="KB913_000561"
     CDS             complement(26621..27289)
                     /locus_tag="KB913_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6818948.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            27431..29767
                     /locus_tag="KB913_000562"
     CDS             27431..29767
                     /locus_tag="KB913_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6818949.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(29882..30193)
                     /locus_tag="KB913_000563"
     CDS             complement(29882..30193)
                     /locus_tag="KB913_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818950.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            30374..31849
                     /locus_tag="KB913_000564"
     CDS             30374..31849
                     /locus_tag="KB913_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBB6818951.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            31896..32480
                     /locus_tag="KB913_000565"
     CDS             31896..32480
                     /locus_tag="KB913_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBB6818952.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            32482..32865
                     /locus_tag="KB913_000566"
     CDS             32482..32865
                     /locus_tag="KB913_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBB6818953.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(33182..33466)
                     /locus_tag="KB913_000567"
     CDS             complement(33182..33466)
                     /locus_tag="KB913_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBB6818954.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(33818..34528)
                     /locus_tag="KB913_000568"
     CDS             complement(33818..34528)
                     /locus_tag="KB913_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBB6818955.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(34525..35997)
                     /locus_tag="KB913_000569"
     CDS             complement(34525..35997)
                     /locus_tag="KB913_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6818956.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            36135..36608
                     /locus_tag="KB913_000570"
     CDS             36135..36608
                     /locus_tag="KB913_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6818957.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(36761..37312)
                     /locus_tag="KB913_000571"
     CDS             complement(36761..37312)
                     /locus_tag="KB913_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6818958.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            37417..37947
                     /locus_tag="KB913_000572"
     CDS             37417..37947
                     /locus_tag="KB913_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBB6818959.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(38430..38873)
                     /locus_tag="KB913_000573"
     CDS             complement(38430..38873)
                     /locus_tag="KB913_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6818960.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(38889..40049)
                     /locus_tag="KB913_000574"
     CDS             complement(38889..40049)
                     /locus_tag="KB913_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6818961.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            40556..42256
                     /locus_tag="KB913_000575"
     CDS             40556..42256
                     /locus_tag="KB913_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818962.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(42358..43191)
                     /locus_tag="KB913_000576"
     CDS             complement(42358..43191)
                     /locus_tag="KB913_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBB6818963.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(43495..45660)
                     /locus_tag="KB913_000577"
     CDS             complement(43495..45660)
                     /locus_tag="KB913_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6818964.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            45920..48214
                     /locus_tag="KB913_000578"
     CDS             45920..48214
                     /locus_tag="KB913_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBB6818965.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            48207..48872
                     /gene="pgmB"
                     /locus_tag="KB913_000579"
     CDS             48207..48872
                     /gene="pgmB"
                     /locus_tag="KB913_000579"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBB6818966.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            48865..49872
                     /locus_tag="KB913_000580"
     CDS             48865..49872
                     /locus_tag="KB913_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6818967.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            49894..50913
                     /locus_tag="KB913_000581"
     CDS             49894..50913
                     /locus_tag="KB913_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6818968.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(51194..52561)
                     /gene="nhaC"
                     /locus_tag="KB913_000582"
     CDS             complement(51194..52561)
                     /gene="nhaC"
                     /locus_tag="KB913_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBB6818969.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(52670..54091)
                     /locus_tag="KB913_000583"
     CDS             complement(52670..54091)
                     /locus_tag="KB913_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6818970.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(54334..56211)
                     /gene="tdc"
                     /locus_tag="KB913_000584"
     CDS             complement(54334..56211)
                     /gene="tdc"
                     /locus_tag="KB913_000584"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBB6818971.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(56502..57758)
                     /locus_tag="KB913_000585"
     CDS             complement(56502..57758)
                     /locus_tag="KB913_000585"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBB6818972.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(57870..58075)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            58338..59639
                     /locus_tag="KB913_000586"
     CDS             58338..59639
                     /locus_tag="KB913_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBB6818973.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(59708..60307)
                     /locus_tag="KB913_000587"
     CDS             complement(59708..60307)
                     /locus_tag="KB913_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6818974.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            60561..61442
                     /locus_tag="KB913_000588"
     CDS             60561..61442
                     /locus_tag="KB913_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6818975.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            61455..63065
                     /locus_tag="KB913_000589"
     CDS             61455..63065
                     /locus_tag="KB913_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBB6818976.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(63142..63801)
                     /locus_tag="KB913_000590"
     CDS             complement(63142..63801)
                     /locus_tag="KB913_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6818977.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVALYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(64084..64749)
                     /locus_tag="KB913_000591"
     CDS             complement(64084..64749)
                     /locus_tag="KB913_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBB6818978.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
BASE COUNT        19458 a        13218 c        11704 g        20508 t
ORIGIN      
        1 atttcctgca tataaatgaa aatgttcgga gtcagccggt gcaatcgtgt gatcactgaa
       61 ttgaatatat ctaaaagcgc cactttcctt atcttctgct tcgaatagat accttacgcc
      121 acggtttcct gcctcgtagg tcaagatttc tttccctaca taacgataat ttgaacgttt
      181 cgttgttcca ttcttaaacg taaatgccat ctctttctca ctgatcttga ttgaagcaat
      241 atctgtttga tagcccttcg tataatattc tttatattct tgtgctgtct tatcctgatt
      301 caatttttct ttatattcaa aaacaggatc aaaagtccca tcttctacat acgtatctac
      361 tgtttgccaa gttcctgccc aatctgaaag agagcgatct tgtacatcct cgtcttcaaa
      421 ataaccgttg tagacgctct tttctttttt gggggtcaaa gtatcttcta gcgggttttc
      481 tgtctctgtc gtttttttca acgcttcgag gtttgcttcc atgatagaaa gatagttttc
      541 tccattttct atttgttcat tcgtcaatcc ttccaaagga ttcaatactt ctaaagatac
      601 acctgcttcg tttgctaacg ttctggcaat actatctttg gcgttttctt caaaataaat
      661 atagttgatt ccatgttctt taacaaagtg tttcagttca gcaattctcg ccgcagacgg
      721 ttcttcacta gaagaaagac cagcaatcga tacttgattc aatccatatt ctaacgctag
      781 atagttgaat gcagcatgtt gcgtgacaaa agatctttgt tttgcttgct taaaggtttc
      841 ttgataaagc tgatggagtg cttgaagttt ctcggtatag gctgctgcat tttttgtcca
      901 tacttcctgt ttttctgggt aagcttcaat cagctgatca cgtatgtttg ctacctgctt
      961 gattgctaaa cttggagcta gccatacatg tgggtctagc tcatgtgtat ggccttcttc
     1021 cccgtgttca tggtcatgat catgtccttc ttcacttccc ggaagtaaaa gcataccttc
     1081 tgtcgctttt atcgtatgga cattgccttc ttgtaatgtt ttttggattg cggggaccca
     1141 tgtttccatg ttttcatcat tataaacaaa gatatctgta tcttggatct ttgccatgtc
     1201 tttagcagaa ggttcataat cgtgggaatc agtccctgct ggaatcaata actctacttc
     1261 tccttcatcc ccgacgattg cttttgtaaa atcatacatg ggataaaagg tcgtcatcac
     1321 gctcaatttt tctttactgt cctcggcttt cccacttgcc ccgcaagcag ttaacatacc
     1381 tgctaaaacc agcatggcca atatacctat caatcgtttc atttatgaca ctcctcttct
     1441 catcttcttt catttgaatg ttccgattcg cttttcgcaa accgtaatag ttacgtttta
     1501 gcaacaggat ttaatttatc atatggttaa aagaactgtc aagcgttttc ttattttaat
     1561 tgatgagaaa gtttatatga atgattgacg atatttttgc aatcaacctc tatcattttc
     1621 cttttatacc cgcttttgtc tataatgaag ttatagataa aggaggaaaa agagtgaaaa
     1681 aagaaacaga tacaacgaat cgtttgatcc gctttttagg aggaaaaacc tcttactatg
     1741 ttttaggaat agttatctta cttgcgctga tcatttattt tttccatcag atctcgttta
     1801 tattcaagcc tgtcggaatc attatcgcta ctatcttgcc cccattattg tttgcactga
     1861 tcttgtatta tcttttggaa ccagtcatca aacgtttgag caagcacctt tcgaggaact
     1921 tgtcagtcat tatcgtttat gtgattattt tatttttatt ggggcttgga agcatatggc
     1981 ttattccttt tcttgaagaa caggcaaaga cattgatcag tagtttgcca gatttgtttc
     2041 aagattttca agagagtctc cgacaatttt tggagaaaac accttttgcc gattcattta
     2101 atcaattttt cgcttctatt gacgacgtga cgtctgatat agctggattt attggaaatt
     2161 attgggaaag tggcgcacaa cggatcagca acattttttc aactgttaca gctattttta
     2221 ttactttatt tactggtcca attgtcgctt ttttcctttt gagagatcct caaaaatttt
     2281 atcagtcagt tttagcgatt gtcccaccag catttcgtac agattttaaa aatttgacaa
     2341 agattgctaa tcaacaattg ggttcatttc taaaggggca aatcattgct tcatttatcc
     2401 ttggagcagt ctactgggtt tgtttcttac tgatcggatt agaatttgct agtgttttag
     2461 ctatttctgc tgggttgtta tgtatcattc catatattgg gccgtttatc gccttctttc
     2521 caggtttgat cattgcattc caagactcta cttttatggc tgtcaaattt gtcattgtct
     2581 ggtttgccgt acaacttctc cacggtgact tggtgattcc tcgagtaatg ggtgatcgtt
     2641 tacagatcca tccgattacg atcttaatcg ttttacttgt catgggtgat ctaatgggaa
     2701 ttgtgggcgt tatttttggt attcctatct atacgttagt caaattactc gttactttta
     2761 ttttccgtaa attcaaacaa cgctacaata aattttatgg cgataaagga gagtatgaaa
     2821 actcttcatt ttctgaagaa gattatttta aataaaacac aaaacgtcga tcttacgaga
     2881 atagctcgta ggaacgacgt tttgtgtttt tgttttaatt tttcagcaaa gcaattgcct
     2941 ggtatggttt tagctccaga ctttgatgaa gaacagtatc ggaataatta tcgataagaa
     3001 tattggcttc tgtgaatcct tctgggatgg cgatccttgt atctttatca tagaaatttg
     3061 ttaatacaag cagctgctgt ccttcaaatt ggcgaagaaa gccataaact tccggatgat
     3121 ttgcttcata agcatgataa tctccttgtg caacgattgg atatgttttt ctcagccgaa
     3181 tcaatttctt gtaataggac aaaatagaat cttcagaaga tagttctttt tctacattaa
     3241 tctcttctag cttgcctcca acttttaacc aaggtttccc tgtagtaaat cctgcttgtt
     3301 ctgtgtctga ccattgcatg ggtgttcgag agttatcgcg agattttgct ttgatccgac
     3361 gaaacgcttc tttttctgtg aatccttgtt caaggagtaa cttataagca ttcaaacttt
     3421 ctacgtcaat atagtcggaa atcgatgaat agtctgggtc gatcatgccg atttcttctc
     3481 ccatataaat atagggcgtc ccacggttca aatggatcat ggttgctagc atctctgctc
     3541 cttgttttcg atactgatcg atagctacaa atcgattgag cgcacgtggc tgatcatgat
     3601 tattaaaaaa tagagcattc cagccgttac cctcactcat cttttctccc catgtatgaa
     3661 atagtcgctt taattctgca aaatcaaatg gaggagtaga ccatttattc ccattttcat
     3721 aatcgacttt caaatgatgg aaattaaaga ccattgataa ttcttctcta ctaggttctg
     3781 tatacaagat acaattttcg atcgtcgtag agctcatttc accgactgtg atgatagtgg
     3841 aatccgtccc aaacgttgct tggttcaatt cttttagata cgtatgggtg attggtttgt
     3901 ccgtatattc aggtttgcca tcattttctt tattattttt caattgttcg tctttaccga
     3961 taacattgat aacatcgaaa cggaatcctt ttaccccttt ttccatccaa aaacgaacaa
     4021 ctttgaatag ttcctctctt actgcttggt tccgccagtt caagtcagct tgtgtccgat
     4081 catataagtg caaataatat ttccccgtat ctccaaatgg cgaccaagca cttccaccaa
     4141 attttgatac ccaatccgtt ggctcttctc ttaaaatgaa gaagtcctga taatgctggt
     4201 cccctgctag tgcttttttg aaccattcat gttctgtcga aacgtgattc agcaccatat
     4261 cgagcatgat ttctatccgg tatttctttg cttcggctat tagctgttcg aattcctcca
     4321 tcgtaccaaa gataggatcg atggctgtgt aatcagagat atcataaccg ttgtcttttt
     4381 gagggcttgg ataaataggg tttagccaaa tcatgtcgat gcctagatca ttcagatacg
     4441 ggagtttttc tttgattcct tttaaatctc caattccatc accattactg tctttgtaag
     4501 atttgggata gatttggtaa atgactttgt ctttaaatgt catggatatt tacctccatt
     4561 caactgattt attacctacc acaacttata tatacaagtt atcatttatt attataactg
     4621 aaccgaaagc gtttgtaaaa tttatcttta tacattctaa gaggtctgtt gcccaataaa
     4681 aaacaagaga tcagacatgt atttgtctat cctcttgttt aaaatagcaa aatattcttg
     4741 tttcttctat aaatggtgtt caaaagcttt tatctacggc aatcagtctt ctcaaatgta
     4801 aaacatgagg agctaatttt atttgagtat tctttttgct cgatgcagga cggctttttt
     4861 acaacctctg attcatggtg ttcaatcagc tgtccttcgg tattagctca aaaaacggca
     4921 aaatatgaaa aactattttg ccgtttgttt ctctaatact caggtcaaac cgctgatttc
     4981 acaacctctg tttttattca ttcgatttca acgcatcaat catatcgata tgctttaatt
     5041 tgaaatgggt aacaatcatc acaataaccg taaatacgat agttaatcct gctgataaga
     5101 cataagccca ccatgtgatc actaatggaa agatgacatt ctccatagac gcttgttgca
     5161 agatgaagtc agtcaatata tatcctacac caaatcctcc gatgattcct aaaagagtaa
     5221 agatgatatt ttctcgaaca atgtacatcg tgacttcttt atcaaaaaat ccaaggactt
     5281 ttattgtaga taattcgcgt acacgctcgg aaatattgat attagttaga ttatacaaga
     5341 cgataaaagc cagcagtcct gataatacga caaagattaa gacaaccgag tctaagttcg
     5401 ccattgattc ttcttgcgtt tcgatttgtt tggacatgaa agacgtattt gtcacagcgt
     5461 ctgtggcaag cagtttctcg gaaagcattt cttcttcttt tgttgtcatc ttatctgtac
     5521 gcagcaaaaa tgcattatcc atcatcgatt gatcagtaac tgaagcataa tattcagggg
     5581 acatataaat aaagctacct agatagtttt tcacgatttc ttttacttcg actttccatt
     5641 ctttttgatc ttcatcataa agcgaaatat gatctcctgt agataagtca aatagttctg
     5701 ctactttttg cgtaatagcg attcctgttt taggcaagga gcgtgggttc tcttcaagat
     5761 cagttaaatg gataaaacga tccaaatcag ctgttttact tggtacgatc actgtcagac
     5821 tttgcgaagc atgtcctttt tttctcaatt ctacggtttg agtatgaata gctaggatct
     5881 catttacttt ttcttgcttc tgcagcatat ccgctgcttt ttgacgacta tcttccgtgg
     5941 atgaatccaa tgtaacgatt gcttgatagt caatgatcgg tccaaattgt ttggctgaaa
     6001 cagaacttag agaatctttc aatcccacgc ctgcaaccat cagcccggca catccagcaa
     6061 ttccgataat cgccataagc attcttgact tatatcggaa gagatttcgg taactgattt
     6121 tttgattaaa gctaaggcgt gaccacagcg gagtgatgta ttcaagaaaa atgcgtttcc
     6181 ctggcttcgg tgctttcggt tgaagcaatg cagcaggccg ttctcttaaa tctttgaata
     6241 aaacgatcat tgcagcgcca aatgcggcaa tgaagaatgc ggcagctgct tgtaaaatcg
     6301 gcggccagtc ataaaaaata agcgcactcc caatatcata ccgctcgtta gacagctcaa
     6361 aaatgatcct tggcaaaaga ttcgttccta atatcgttcc taaaacaata cctatccctg
     6421 aggctagact tgcatagatt gcatattttt ttgcgatttc aactttcgta taacctaacg
     6481 cctttaatgt cccgatttcc ctgcggtttt cttctaccat acgtgtcatt gtcgtaaagg
     6541 tgatcaatgc ggcaataaag aaaaagaaaa caggaaaaac attggcaatc gcagcgatac
     6601 gatcagacag atcaccaaat tcttgaaaac cgacattttc tgaacgttca ttgtataggt
     6661 atgatggttt agttaaattt tcaatttttt ctgcatttcg attcaattct tcctctgcag
     6721 aggccagttc acgttctttc tcaactaatt gcctttcttg ttcagcaagt tgagcttctt
     6781 gttgagataa tgtttgaaca gcgattgttc gttgcgcttc aggaagctgc tggatagttg
     6841 ctgactgttg cgctaactgt tttttagcat cttctaaccg tgttcttgct tgcgttgttt
     6901 gtgctttgcc atccgctatt ttttgctgtg ccggttctaa ttcttcgttg gccgattttt
     6961 tcagctcttc taagcgttct tcgggtcgat cttgtaaata cttttctgcc ttttcttgat
     7021 tttgctccat tttatctttg taagctttgc tgtacgtatt caaattcttt acgtttgtaa
     7081 aatcaagata taagacagaa taaatatctg ttttaaaaac ggattcaggt aaatagacaa
     7141 aataatcgac gctaccattt ccgacgttcg cgtatcctct ctccaaattg ttgatgaaca
     7201 atggagaacg gacaaagccc gtgatggtat actctttttc tttcaattca tctgaatcaa
     7261 tctgataaat atcaccgatt ttataccctt catcttccgc tttttcatcc aatacaagct
     7321 ggtttggttt ttccgggagt tttccatcag ttaattgtag cttgttctgc ttgttatttt
     7381 tgttataaga aaatatttga atcacttcgt ttttgccagt attggaataa tagatctgtt
     7441 ttcctgtttc tacttttgca tctgggatct tttctgcttg agcaatatct ttttgtgtca
     7501 agccaccagt agaaacgatt tgcaaatcag aaagtcctgc tgtaccaaca tagtgatcca
     7561 tcgttttttg catgacaggt ccagcagttt tgacacctac aaataaaagt gttcctagca
     7621 tgacaataag gatgattgca atgaatcgtc ctttagattg ccgaatttcg cgaaaacctg
     7681 ctttaagata tgttcttgtt ttcataaaat ccccctacca tacaatctca tcaatggatg
     7741 aaggatgatc atttaattca acagacctta ctttagcatc attaatgtga atgactctat
     7801 cagcgatggg cgctaaagca gaattatgtg taatgatcaa aacggtattg ccgtgttgtc
     7861 tgctagcgtt ttgcaataat ttcaatactt gcttgcccgt ttcaaaatcc agcgcgcctg
     7921 tcggttcatc acataaaaga agtttgggat ttttagctag tgcacgagca attgaaaccc
     7981 tctgctgttc gcctcctgat aattgggacg gaaagttatt caatcgatga gctaggccca
     8041 cttgcctcaa tacctctaca ggatcaagcg catcaggaga aacttccgtt gccaattcca
     8101 cattttcttt tgctgttaga ttaggaacga gattgtagaa ttggaaaacg aaccctacat
     8161 ctgttcgtcg gtaagcagta agctgtttat ctgaaaattg cgcaatatct gtgtcatcaa
     8221 taatgatctg accttcatca ggtgtatcca tcccacctaa aatattaaga atcgttgact
     8281 ttcctgctcc acttggacca agtataatca ctaattcgcc tttttcaatt gaaaaagaaa
     8341 tatcgtcatt tgctgtaatg gtcgtttctc ccattttgta tcgtttgtat tcatttttta
     8401 cttcgacata cttcactctg attcctccat tttcacgata tttctcgcta tatctatgca
     8461 tcgaatgcgt tttctcacac ttatttattt taccactgaa tttctctaga ctaaagaaag
     8521 gaatccttta atttagttga caaataaacg atttatgatt tacttacata aaaaacattg
     8581 ttatttgaaa gaaggaacat catgaatgat ttaaaggaaa atatgatttt tgatttatca
     8641 aaaactgctt ttgtcgcgat cgacatgcaa aaagagatcg taaataacgg tacactctct
     8701 ccacacactg cagcatctat tctgacaaac aatgatttgt tagtaagaac attgaaacgt
     8761 accgctgcct tgaaagtttt agtgaacgta gacatctcca ctttccctta tttgagtcaa
     8821 caaactgata tgggtggaat gactgcttct gtacctccag aattcactga tttacttttg
     8881 aaggattctt tgaaagatac agataatatg ttgactatca caaaatacaa tccaagtgct
     8941 ttttttggta cttctcttga tcttcaactt cgccggcgtg gaatcgaaac tatcatttta
     9001 agcggtgtag cgacaacaaa cggtgtatat gctactgcat tagatgcctt tcaacacggg
     9061 taccatatcg tgcttgctga agatgcttgc agtgatcgtg acaaagaatc ccatcaattg
     9121 ttcataaaaa agatatttcc gaaaactgca cgagtacgct caacgaaaca aataatcgaa
     9181 gctatccaac aaagcaaata agtactggca cacgtgattt tcatttactt ctttttgatt
     9241 tcatgggaaa ataaccacag gatttagata ggagtatgaa catggtgaaa aaaaagatca
     9301 caatcaaaga agtcgctaaa ctttccggcg tttcaatcac aactgtctcc ttgatattaa
     9361 atggaaatac ggagaaattc agtccgaaaa ctgttcagaa agttttagct gccaaagaag
     9421 aattaggcta tcagcctgac tattttgcta gacaaatgat taccaaggaa acgaaaacaa
     9481 ttggtgtact cgttcctgat atcacgaatc cattcttcag tacactgatg cgaggaattg
     9541 aggatatctt gtataagcag aatttcgtca cgatattatg taatgctgat tctgatcatc
     9601 aaaaagaaat cgaatatcta gccgagctca cacgtcgagg tgtggatgga ttcattatcg
     9661 cgacttctgc tgtctctaca gatgcaatca acgaaaattt gaaaaaacaa ggccggccct
     9721 tcattgtttt ggatcagaaa aaatctgaag gatttagtga tgccgtacga acagacgatt
     9781 ttcgcggtgg ttacctagcg ggcatgcact tgcttagtct aggacatcaa acgatcgccc
     9841 ttgtctatcc tgaaaatcca ccggaaaatg tccacgctcg gattgagggg tttaaatctg
     9901 ctcttgatgt ttaccaaatc cctcacgacc aactgatcct cttacctaca cagttctcaa
     9961 aacaaggtgg ctaccagatc acagcagaac ttcttgattc tgctgcaact ggtgtgtttg
    10021 ctttaaatga tgaattagct tttggattat atcgcggatt agaggaagct ggaaaaagca
    10081 tccctgaaga ctacagcatt attggctatg ataatataga tatgtgcgag tatatcaagc
    10141 cgaaactgac aacgatcgca caaccaatct tcgaattggg acaaacatct gccaagttat
    10201 tgttagatcg gatccaattc ccagaaaaag aatgggaaga aaaaagatta cctgtacgat
    10261 tagaaaaaag attttcaact gcacccttga aatagctttc aaggtgtgct atatttttat
    10321 cgaactatta aaacgtttta ctaaaacgtt ttaaaaaata attttcccat caaaataaat
    10381 gagatagttg gaggtttgta aaatgaacac ggttacagta attggaagta ttaatatgga
    10441 cactaccctt cgtttaacca acatgcccaa gccaggcgaa acgatgcatg cgcatgagat
    10501 ttttcacgct ggcggaggta aaggtgccaa ccaagcagtg gcagccaaac gttcaggcgc
    10561 acggacatct tttattggag gcgttggggc tgacagcgaa ggacaacagt tattagatct
    10621 actgacaaaa gaaaacatcg atacatctgg gatagctgaa atccaaggcg ccacaaccgg
    10681 acaagcaatg attatggtag acgcagcagg agaaaatagt atcttgatcc atgcaggggc
    10741 aaataatgct ttccatgaac aagaagtcct aaaaaacaag caactgatta caaacagtga
    10801 ctttattatt gctcagtttg aaagtagctt agatgcgacg atcctagctt tttctattgc
    10861 aaaagacgca ggaaaaacaa cgatcctgaa tcctgcacca gctcgtgaaa cgattcctac
    10921 tgaactactt gaaaagacag atatcattat accaaatgaa acagaaacag aaatcattac
    10981 aggaatcaga gtgacagatc ataacagttt ggtcgcagca gccgaaaaac tccatgaatt
    11041 aggtattgga acagtaatca ttacactagg cagtgccggc gctttctatc atacagaaaa
    11101 agaacacggt atcgtccctg cttttaaagt ggatgccgtt gacacaacag ccgcaggtga
    11161 tacatttatt ggcgcattaa gcagcacact tcagccagac cttagtaact tgaaagaagc
    11221 gatcctttat ggaaatctag cctcttctgt tgctgtgcag tcttatggtg cgcaaccttc
    11281 tatcccttac cgcgaagctt tagaacaatc agcagtctaa aattaacaat gagaggaaga
    11341 aacaaacatg aaaaaaggaa aagtaatcaa ttcagatatt tcacgagtaa tcgcacaaat
    11401 ggggcacttt gataaattaa gtatcgggga tgcaggcatg cctgtcccct ttggtactga
    11461 aaaaatagat ttggctgtct caaacggtct tccaagtttt ttatctgttt tagaaaacgt
    11521 tttagaagaa cttgaggtac aatcgattga attggcggaa gaaataaaga caatgaaccc
    11581 ggaaatattg gaaaaaatca aattattgtt accagataca ccgattagct ttatcccaca
    11641 tgaagaaatg aaaaaagagt tgaataactg tcatgcattt attcgtacag gcgaaatgac
    11701 accttacgcc aatattatat tagtgagtgg agtggtcttc taatggaaac gacaatgaat
    11761 cctgaacaga tggtactgtc cgagcagatt catatgctga ttgaacagtt gggaggaaaa
    11821 gacaatattg attctgtcct tccatgtgcg actcggcttc gtatcaaatt gaaaaaacag
    11881 ccagtagcca atgcagaaaa attaaaacag caaatccctt ccattaagta tttcatttta
    11941 ctcgatagat atgcagaaat aatcatggat cagggattgg ctcctgctta caaggaattg
    12001 acgcgtcaaa tcgatcattc agctccgaaa gaaaagctaa atccgatcga aaaactattt
    12061 ggtttgatat cggaaatctt tacgccgatc attccgctgt ttgccggttc tggtatatta
    12121 aaaggtctgg ttgttttagc gactacgatt ggctggctta gtgaaacaag cggaacttat
    12181 catattttgt ctgctgcgtc gaatgccgtc ttttattttc tgccaatctt tcttgctttt
    12241 tctgctgcca aaacgtttaa agtgaatgga tatattgcgg ctgtcattgc tgcagcactg
    12301 attgaaccga atctgacctc tttactttca gacagtggca aagcagctac tgattttctg
    12361 gggattcctg tagtactgat gcagtatacg tctactgtca tgccggcgat tttaggtatt
    12421 ttcttttatt cttttgttga aaaattcctc aaaaaatata ttcgcgaaaa tatgcaatta
    12481 gtatttgtac ctttactttc attagttatc acggttcctt tgacgttaat ggtattcggg
    12541 cctgcgggtg tttaccttgg cgaaggttta gctgccgcaa ttacttggat gatggatatt
    12601 aacggaccga tcagtggcgc aatcatcgct ggtggttgga atattttggt aatatttggt
    12661 atccaatggg ctgtaaaccc tgtcatgatc agtaatatct ctgcttatgg gttcgaccga
    12721 atcgttccgt tgacaggagc agccaatttt ggaatggctg gtgcagcttt aggtgtattt
    12781 ctgcgaagta aacgttcaaa aacccgttcg atctccggtt ctgcttttgc ttcgatttta
    12841 cttgcgggag tgaccgaacc aactgtttac ggaattgcga tcccattgaa aaaaccattt
    12901 gttgctgctt gcattggtgc agctgctggt ggagctgtaa tgggatttgc ccaagtgaaa
    12961 gcgatcgctt ttgtatttgg tagtctgacc acattgcctg cattcatttc cggtactttt
    13021 ttctggtact tagcaggact ggctgttagt ctagtcgtag caatgatcac tactctcgtt
    13081 agcgggtttg atgaagacct aatgtcttat gaatagttaa tgaaaaagac tgaagtatga
    13141 gatgtttatc acatatttca gtctttttct ttttaggatc attattttta taaatttttg
    13201 tgatactttc caaactttgg tataatttac atatgcataa ccatttttat ccccacttgt
    13261 ttatccccaa acaaaggtgg tctatgcaat aaaatgaacg tcaaagaaaa acgaatgaat
    13321 gctcgttgct tatttacaaa ttgttttatt tagaatacac agacagattt atgaaaagaa
    13381 aaagcttttc gacacgatta tctgttccaa aaaatgtcta atgaatgctg aataagacag
    13441 aaaatcaatg aaaggaaaag gactagttta ttatgaaaaa taaaaaaacg atacgtttgc
    13501 tagctgctac ttggctgatt gctccgtctg ttttgtcgac caataccgta tttgccgtag
    13561 ataatcaaat agctgatcaa acagtcacaa cagatacgac tacatccagc tcagctacta
    13621 gtgaaacaac ggattctttt acagaagacc caactggaac aactaactca acaacaggat
    13681 cgaccgagcc aactgaaatt gatccggctg atccatcaga aaatgaaaag ccagccgaga
    13741 catattccct tacaattgct ccttctttga ttggtaagat ccaactgact gcttcgacag
    13801 cggattcccc tgaacagcaa cctttggata ttacggaaag tggaacggta gaaggtttat
    13861 tagcggaaac gaaggtaact tacactatta cgccagctga aggtgaacaa attgcttcag
    13921 tcgctgttaa tggtgccaaa gaagtaaatt atgatgcaaa gacctttaca gtaggtacga
    13981 acaatttatc tattactgca gaatttaaag ctggaccgga tacttcaaca gagaaaccaa
    14041 ctgatcctag tgaagaagtc cctagtacac cagatccgga aacgccaaac aaaccagatg
    14101 tgggtaataa caacaataat aatggttcaa ataattcaaa caataataac aataattcga
    14161 acagcgggaa ttcttcgaat caaacaaacc catctggatc gaataacaat ggaaatactc
    14221 agagagaacc aaaccatcca aacaatggtt catcgaatgg cggaacgaac aatgcttcat
    14281 ctcgtccaaa tacagcaaat caaagcggta tagagaatcc atcttctgct tcttctgatt
    14341 ttgttgtaaa atcaccaatt gatgctgtat tgcctacaaa tacaacgaat gtccaacaag
    14401 caatcgttcg agaagcattc aagcatcttg gaaaaccata tgtatgggga gcaaaaggtc
    14461 caaatacttt tgactgttct ggtttgactt attacgtata tatgaaagca accggtcatt
    14521 atatcggtgg ctggacaggc gaacagcaat atgcaggtac gcagattcca gtaagtcagg
    14581 cccaacctgg cgacctcgtc ttctggggac cttcttccgg tgttactcac catgtaggta
    14641 tctatattgg gaacggacaa tttatccatg cgcctcaacc aggagataaa gttcgagtaa
    14701 cttctatttc agatttcacg cctgattttg ctgtccgagt aaacttagca ggtttacctg
    14761 ctgcttcagg ttcgctgaca ggcggctcat ctattttaga tggattagat ggctcgttcc
    14821 atttcagtca aaaccaaaca actgatcagt tcttgaaaaa gattgcagat gatgcacagg
    14881 aaatcgggca aaaagaagga atctacgcat cagtcatgat ggctcaagct atccttgaaa
    14941 gtggatctgg aaacagctta ttatcaagcg aaccaaatca taaccttttt ggtatcaaag
    15001 gatcatataa aggaagcagc gtgaccttca atacacttga acaagatagt tccggacaaa
    15061 gctaccaaat ccgcgcacaa ttccgtaaat atccttctta caaggaaagt ttggaagact
    15121 atgccgactt gatcaaaaat ggactgactg gcaatcctga tttctacaaa ccaacttgga
    15181 agtcggaaac aaaagactac aaagaagcaa ccaaatattt ggaaggacgt tatgctacag
    15241 atcgccaata ttcacaaaaa ttgaacgcga tcatcgaagc gtacgacctg acaaaatatg
    15301 atgaaccgaa aaaagaagca gcaacaactg aagaagcaaa cgctgaaatc ctcaatatgt
    15361 ctaagcgatt cgatgtgcca atcaaatgga caacagatgg cgtgccaatc acaggattag
    15421 aattttcaac gataaaacgc gtcaacaacg cttcttccat cttccgtgtc gcttcaatct
    15481 gggatttgtg gaacaatttt acggcaagac agataccaga aacaactact cgtacagtta
    15541 aagctgcaac tgttcctgta ctaaccttgt taaggttaga caaatcattc tggcttgatc
    15601 tgcctttaaa gaaatagaat aaattaaaaa ggggatgtga cactgtcaca ctcccttttt
    15661 aatttattct atttctttat atttattttg tattccgtta caaactcgcg tacttggtta
    15721 ggttccagag tgacatctcc aaaactttca agtcgctccg ctcctggcag ttcttgagtc
    15781 tcaaatgtga taccgccatg atttactaat ttattcccgc gcatttccgg tccatcttct
    15841 ccaaaatttg ctgtaaaaat cacgattcct gaagcatctg tttttacttg gatcgatact
    15901 ttttcatctg ggcttgtcaa ttccgcagca tttagtaaac cagattgttt tttcaacaaa
    15961 aatggatgat cgatgccgcc cactatcatt gattggcgaa aatcactggc aaagacctca
    16021 cctaattttt taggacgttg gaagtcaaat gctgtgccac ttactgaaac tacttctcct
    16081 gtaggcgttg tatctttatt gagcgtagca aataatcggc tattcaacca aagtatatgt
    16141 tcgtcgattg actgtgctgg atcaccggtt aaattgaaat agacatgatt tgtaggattg
    16201 aatactgttt tgcggtcact gatcccttgg accgtcactc gccatgtatc atcgttcgtc
    16261 agcgtatacc gtacttctac atctaaagtt ccaggaaatc cgttttccat atctgggcta
    16321 gtctgataga aaatgaccga tgcttcgttt tcaccattga tgactgtata atgccactgc
    16381 ttggcttcaa agctaggtgc accaccatgt aaacaatgac cagtgtccgg gtctgttttt
    16441 acttcgaacg tttcatcatc taatttgaat gtgccattcg taatccgtcc agccatacgt
    16501 ccgattgaag caccgatata agggtctttt tctagatatt cttttgcttc atcaaaacct
    16561 aagatcaact ctcgtttttc attatcgatt attgtttgaa aatgaacaac ccgtgcccca
    16621 agatcactga cagacaaaga tgtcccattt tgattcgtga tcgtaatcaa gtgatagttt
    16681 tcgccaaaat tttgttcatt gatttccatg ttccttgcac cctcttttct ttcatttgca
    16741 ctgattccag tatacatgga aaccgttttc ttaacagctt attccgtgag taacgagaaa
    16801 aaatttacta tattctaata aaagaccgtg aaaaaaaggt tgtgacaaaa atattgtcac
    16861 aacctctttt tccgaacaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc
    16921 aaacgaaaaa tatgaggagc tatttttgct tggctgttct tattacttga tgcaggacag
    16981 ctttttcaca atctcttttt caatacgatt ccagtatata accatgtcgt cagtacatag
    17041 tagatgaaat acaatacgaa gaatatcgta aacggaaccc aaatatcttt gtatggattt
    17101 tgcatgaata gaccaaacat ttgtaatccg aataagacat ggactacacc taagattcct
    17161 ggtgctaaga ataacacgcc tacttctcta cggatcgatt gtttaagcaa cccgcgtcgt
    17221 gttcctatct tttcaagcat ttcataacga gcaatgtcac tcttgcttcc tgacaagatc
    17281 ttgaacatca aacagctagc aagcatggtc aagaaagcta aacctaggaa gaatcccata
    17341 aattcaaaac cagagaatag accattatac acttcataca tttcatattt ctggttgctg
    17401 tactctactt tttgcaaaga tggattgttc attttatttt gagcaacaag tgtttcgatt
    17461 ggtttcaggt ttgcttggaa gtcttttacc tgaactagct gtaaagtgga ttgtggcaag
    17521 ttcagttgat caaattctga ttgactgact accttgattt ctttttcttg ctgttccggc
    17581 aattcatagc ttcgaagttc ctcttgtaca gtcagttcat tcattttttt agcaggaact
    17641 ttttctttcg tgatcttcgg cggtgttcca tcttcatgtt ttatcatgat caatggttga
    17701 gccgcaaatt cacttgcatt atagtaaatc gttcccgcat cttctttttg agtataagaa
    17761 gcagaaagtg ttggtgaaag ttctttgatt ttttgctgat cttctgcccg aggattattc
    17821 atcactagat catatccaga attgttttct gtcaagtctg caatttcatt tttaaaacct
    17881 aatcctaccg tcaaagcgcc cagtgccaag gcaaacagca tagcgaccat tgagagcatt
    17941 tgtgtatatt cacgaatacg aaagtttaac tgtgacaatg tgaaattgtt caattttttc
    18001 aatgaaatct gttctgattt ctttagtaat gataaaaaga aaatgatcac agaatggaaa
    18061 atgaaataag ttcctaatac gatcgtaact aaggctaccc ctataccaaa gacttgatag
    18121 gtccccacgt gtttcatcat atagtaaccg cagcctagaa aagcaattcc cagtactact
    18181 tcaaggaaaa acaagaattt atgctgcttg attcttgttg gtgtctgatc cgcacgaatc
    18241 aatgctaaaa tcggtttttt gacaatcgaa aaagcattga caacagcagc taataaaaac
    18301 aaaacagcaa aaaacaaaac agtgatcaac aacccgtgaa tactaaaagg tgtaaaatgc
    18361 gaaatattga gatctaactg atccactaat aatcggtgga cgatacttgt caatcctaca
    18421 ccgacagctg aacccactaa agtagctgcg atccctacta agaatgtttc agaaaaaatc
    18481 atctgtgcga tttttctgcc ttttgctccc agcatcataa acattgcata gtctttttgc
    18541 cgcatcgtca tcaaaaagga atttgcatat aaaatataaa cgaatgtgat gatccctagt
    18601 aaaacagaac cgaatcggaa aatgataact gtagccgcaa cgatcgtatt acttttcaaa
    18661 aaagcttcgt tgcttgccat tgattcaaac atgtaaaaaa tagcagatgc cataactaat
    18721 cctgagaata acaccaagta gtctcttaaa cggctcttga tcccagtaag tgataatttc
    18781 caaagcatag tcaatctccc cctactgttc caagtttcca agaatagata gtatttctcg
    18841 atagaaggaa tcacggcttt gatctccacg tttcacttct tgatggatac cgccatcctt
    18901 gatgaataaa atacgttggc aataacttgc agaaaacgga tcatgcgtca caagaagaat
    18961 cgatacatga tcttttgtat tcaattcgtc catcgtatct aaaagatccc gggcactttt
    19021 ggaatccagc gcacctgtag gctcatcccc taatagaatc gttggttgtg tgatcaatgc
    19081 acgtgcggcg gcgacccgtt gtttttgtcc accggaaatc tcagaaggat agctttccaa
    19141 aatatgagag atggataaac gttctgcaat tttttggaca cgttgcttga tttcttttgg
    19201 tctgacgcct tgtaaagaaa gaggaacagc gatattttct tgtgctgtca agctttctaa
    19261 taaattgaaa tcttggaaaa taaagccaat ctcattcgca cgaaaatctg ctagttgatt
    19321 tccttttaat gtggtcacat ctttttgatt gattcggata tgcccatctg ttggtttatc
    19381 taatgtggat aaaatattca aaagtgtcga cttaccagaa ccagaagcgc ccatgatccc
    19441 aataaattcg cctttttcta catcgaagct gatgccgctt aatgcttgcg tctttttctc
    19501 attgtttttt ccgtatactt ttgttacatt ctgtacttcg actattttgt tcatttcttt
    19561 ccctaccctt taattagttt ttccagtgct gttttcggca cgtctttttt ttcgacttct
    19621 tcatacgaag tgacaccttt atttttgttc caggtgattt ttaaatatgc tcctttacga
    19681 agcggtcgag tcaattgtcc cttgaagtcc agttcttttt ccttaccctc tttcgtatag
    19741 ccaggcagga tatatctata gttgactgtt tcttgtccag agtctgattt tgaaactgtt
    19801 tttgtaccat ctgtcgtaat ttgtacatag tattcttctc cacccataac tacgtaatct
    19861 gcgattttca cccctgcaag taccacaacg atgaaaacaa gtagaccgat cagaagtttt
    19921 ttcacttttt ccccttctct cttactttat atactgatta tagaaaaaag cgaacaattc
    19981 tgccttcgaa tcaactatca ttcttctttc aattttgtca ttttctttaa aacaactaaa
    20041 aaaagagttc aagacaataa tccgtcctaa actccttctt cctatcttac aaaaagtatg
    20101 tcacttacgg tctttcatgt cgcctgtatt gataacaggt tgcgttcctt tgtctgtaat
    20161 gattgagaca agtaaattat tgatcaattg gactttccga tcatcggtga aattgatttc
    20221 ttgtccatct tcgatttgct ctaaggccat ttgagtgatt gtgacagctc cttcaacaat
    20281 ggtttgtcga gcagacaaaa tggcttttgc ttgttgacgt tggagcatgg cactagcgat
    20341 ttctgttgca taggctaaat ggttcaagcg tgtttcgatt acttcgacac ctgctactgc
    20401 taaacgctct tgcagctctt tttgcaactc gtcagacact gccgtcgtgt ttcctcgaag
    20461 cgtcaaatca ttctcattga atgtatcata cgggtattgg ctagcgatat gccgaatggc
    20521 tgtctcactt tggatttcta caaaatcttg ataatacgct acatcgaata atgcctttgc
    20581 tgtatcaacg actttaaaga ctactactgc tgagatttcg atggggtttc catccaaatc
    20641 attgactttt aaaacagaac tattgaaatt ccgaactttc aacgaaacag tcattttttg
    20701 tgccaaaggt atcgtaagga aaaagccatt ttctcgaatc gtacctaaat attgtccaaa
    20761 aaacaaaatt acttttgctt gattaggact gactacagtt gccgaactta acaacaataa
    20821 cgtgatcaac caaagaaaaa tacttaaaaa aagtgcccaa actttcgctt gccacatacc
    20881 taaatagaag aaaaacaatc caactaaagc taatacgacc aatccgacaa tccctgcata
    20941 accattgata taaaatgctc ttttttctct catgctactt cctgcgctcc tttatccttc
    21001 aataaatatc taatgttact tttttaattt ttttttcgaa tacgcgccat tacaccttct
    21061 agttctaact ctttgtcttc agtgatgtac caaccgcttg cctgtgtccc tccggctgcc
    21121 tgcggtaaat aatccaattt tgttcgaacc cagtgctttt cttctgtaaa atagtcttct
    21181 accaagacct ctagatccat ccctgctgaa agaggcaaat cttcccgaac agatttaaag
    21241 ataaatcgtt ccttcttccc atcatacttc aatattcctg tatcgataat cggtaaagaa
    21301 taataatcca gctctttctt caccgtcaat aaatgtttga aaacttcatg gtacacttgc
    21361 tctaattggc gaccttctga attgttcggg taattaacca tcactttttc tttgtctgga
    21421 tcatagaagg tttggcttag ttgagtgata taagtatgta atctttccat ttctgttttt
    21481 aacttttctc tttgaccttc ttctaccttc atatactctt tcaccctgtt ttctttttag
    21541 atattttctt tcttatttta ctatagttat gtgcgttaag cgatgaaaaa cagcaaagat
    21601 tggaaggatc tttgctgttt tttcttaaaa tatccagttg agtacaggat caatctgttt
    21661 cattgtcctc ttgatccgtc gtaatattga tcgatgtgtc tttagcagtg atctttagct
    21721 ttttctgtcc ttgttctaac aaagtatttg ttattggctg gtagtctttt tcaatataag
    21781 attcaccaga cgtttggata gtatagccac tgttttccat ctcatgcaaa gataaattgc
    21841 caccgtttag gatgactttt ccttctttgc tgatcaaact gtcttctaga tggaagttgc
    21901 tgttttcacc tgtgacgatc aagttatcca cattggcctc atctaatcga agtgagccta
    21961 attcatcttt cgcagttatt gttcctcctg taaattcatt gaacgatacc cagccatcat
    22021 gtgtcttagt attcactttt ttgattgata cttcgttgat atcaattgca ctattattcc
    22081 cttcgattgt caattcagat aattcatgat ctgcagggac aacaatagtg atttgtgcac
    22141 ttgtgtcttc taaactaatg attgcacctg ttgatttttt gactgcattc acagtcaaca
    22201 cgccattttt ctcctttatt tctggctttt ctgtcttatc ataagtcgtt tttatctcaa
    22261 aatccaatcc gcgtatgacc gaaactgttt gattttctgc atggatgacg attttgtttg
    22321 catccttgat tttttttgtc tcagtaacca tatcgatcaa ccgaggacca ttatcccaag
    22381 tcagactctt ttgagcgcct aatgtataag ttgcacctgc taggaggcca ccagtaagca
    22441 tcagaccaat accggtaatc aaaaaatgtt tcaatctcaa tttatgtgtc ctccttcaaa
    22501 cgcccgctga atgcagatct ctttttgtaa taaaacgtcg tcccatccat ttaacaaagt
    22561 tcatcatgac ataaaaaagc ccttttgttc ctttcagcaa cagtggcgaa ataaatactg
    22621 cgcttcctgt ggcgaacaga ccgacaccga taaagaataa tccactcaga atcgattgtc
    22681 caaacacact gattcctgag atgatcatga ataggccaac acctaagata ctgatacata
    22741 aaacatagat actaaaaatg agcgctagta aagcaaccaa tagtccccca ataaccaata
    22801 taaaccccag tgctagtgga atgaggacag gagaagcaaa taaaccgata atgattaacc
    22861 aaatcaggcg aatttgtctt tttggatttt tcactaactc gttttctgct tgttcttctt
    22921 ctgaaaagta actgattttt aattttaagg caaactgctt tggtgtacca tattcatcaa
    22981 tgatctgatc taatgttttt ccagaatcta aaaaatattc ctcataatac tggatcaaat
    23041 caaaacgatc gtcttcagga atttcttgaa gatgatccac aacttcattc aaatattcat
    23101 tcatttgtgc tctcctccaa taaccggtct aaagaatctc gaaaaacaat ccattcatca
    23161 ataatttctt ctaaatgacg acttcccatt ggtgtcaacg agtaatatcg acggtttctg
    23221 ccttcaaaag gttcatcata ggtctcaaga tatccttctt ttttcaatct tctcaaaacc
    23281 ggatatagtg tagattcact gacagagaga ctttcttgta cgatttttgt taaggcatac
    23341 ccatacatat cttccttgct taatgctgct agcacagtac catcaagaag aacagttgga
    23401 atctggatgt gcattacgtc accttctatt ctcaagtgta atattttatt tcaatctata
    23461 ttatacaaca tataatatag tttcaaaatc agtttgtcaa atacaaaaaa actgactaaa
    23521 agatttgatc ctttttagtc agcaaaaaat ggcttctctt tgatttttat tataacagtg
    23581 gcataatcca atttgtccac atccagctca gtggcatgat aacgatcatt gcaggtatca
    23641 tgtcagctac tgggaacatt ttcacgttga tcattctaaa accggtagcg accatcaaga
    23701 atccgccgca agctttaaaa tctaagatca tgtctggtgt agtcaatgga taaataaatt
    23761 ttgccaataa gaacaaaata taaaaaataa tgaattgggg aattgctatc acagaaacga
    23821 cataccctaa attacacgca aaaatagctg ctgtgaaaaa atcaaggaca gatttagaaa
    23881 tcaaaatcgt actgtctcct gtcatcccag aatctaaact tccatagatc cccgtaccac
    23941 ttgcacaaaa tagaacaatg accgtcacta atgtgctgat aaattcatcg tgggtcatac
    24001 caagcttttc actagggaag attttagaaa taggtacttg catcagcgca gcccccttat
    24061 ttatcccatt acctaaatga acaatcaaac caatcgctgt tcctatcact aaagcaaaaa
    24121 taacagccgg catatttttc atcggcgcaa tggaatagat tcccatcccc atcgaacaca
    24181 caccaaaaac catcgtcagc tgtgctttaa aatgttcact taatttattt cctactaatc
    24241 cgccaattag tccgccaaac aaaacggaac ctacattgat caaaactcca gttggcatca
    24301 aaaaactcct ctctttttct acgaagcgaa aaaaatcaga aaaatttctg taattattgc
    24361 tttcgctgca agaaagattg taacagacag agaagattac accaattcat tttttgtgtt
    24421 aaagtattct ttattggaat aagtaggagg aatatgatgg atatccataa attcgaagtt
    24481 tttcttgatt tagccgaaac aatgaatttc accaaaactg ctgatcgaca attcaccacc
    24541 caaggaaata tttctaaaca gattctttcg ttagaaacag aattagacgt caaattattc
    24601 gaacgcgccc atagaaaaat cgaattgacc gaagctggaa gcttattgct cccatatgta
    24661 aaaaatgtcg tagaacaata ccatgctatg caagaagtgc ttgaaaccta tacgaaagac
    24721 aacaatcttt cattaaatat cttaacgata ccgacaatga tcaattataa aggtttttcc
    24781 aaaatcaccg agtttttgaa acgccatcct gaatttacag tccagttgaa agaagtggaa
    24841 agtgtcgaat taacttacaa tgacgccaat gaacatagtg acacgatcca ctttgctaga
    24901 agtttccagg ccccaccaag ttcgattgag tggttgccta ctgaaacaga cgattttgta
    24961 gcagttctac ctaaaaatca tcctttagct agtaaaaaga aattggatct aagcgaactg
    25021 aaaaaggaga actttttgct ccttggcccc actacgaact tgtatcaacc tgtactagat
    25081 ctgtgtcgcg aagctggatt tgaaccaaaa atctcttata aaggagcaag aatcgacttg
    25141 atcatcaata tgattgcaaa tgacatgggg attgctattg ttatggaaaa aacagtcaag
    25201 aatctattaa aagaaaatac tgtgattctc cctatttctc caacaacaga gagttatctt
    25261 gcatttactc gtaaagtcgg tgagcattct ttggcttcag atacattttg ggagtattta
    25321 aatcaagaag aaaactaagc cctacatttt ctgtccatct atccacccaa aaaaagagag
    25381 cgacgcatga ctttcgctct ctttcttgca tcatgtcctt gtttcaatga cacctctaac
    25441 atttctcgta gttcaataag aaagcagcga tttttatgcc aaaagaaccg taagaacatt
    25501 tccctaatca caaaaaaacg actaaaaacc cctaaaaacc ttcaatagaa tttttagggg
    25561 ttttattctt tttcctattg tttacttaac cgtatcattg ctgtcgttcc tactccttcg
    25621 atactgctat aatcaatacg tccatcatgc agttctagaa tttttttaac cagtgaaagt
    25681 cctagcccat tcccagaaat ttgacgactt gtatctcctt gataaaattt ttcaaacatt
    25741 cgatctctgg tctcttcatt cattcctaca cctgaatcgg tcacttccag tacaatctct
    25801 gtggctgtct caaatagttt gatatgaatc tgtccattga tttgattgta ctttatggcg
    25861 ttatccatga tattcagcca cacttggtac aaaaactctt cattgcctgt gtaatttact
    25921 gcagcaagtt cgatatccaa ttctagctgt tctttctccc atttaggctg aaaaaaaacg
    25981 attacttctc tgatttgttc atctaatcga tactctttct tttccagttg gatacgctgg
    26041 ttttccagtt tgttcaattt taagatgttc tctgttaatt gtgaaagctg cgtgatactt
    26101 tcgataatcc gatataaaaa tatttggcgt tcttcgtcag agagatttgg ggcttgtaac
    26161 aattgaacat atccttggat tgttgctagt ggtgttttga attcatggga tacactggac
    26221 acaaagtcat tcctcagtgt ctcgatacta ttgagttctt ggaccataac gttgaaatct
    26281 ttatacagtt gctgtacttc tgctactttc tgctgttcat ccattcgaat cgaaaaatct
    26341 cccgttgcta ccagactcat atttgtccct agcgcactga ttggatgcag gatacgccgc
    26401 ccaacaaaaa tcgatattcc tgtacccacg accatactga accccgcaaa gacgaataac
    26461 gggtataacg ttggttttcc agccgattca gcaggcgaga tagaatgtcg agacaataag
    26521 aaaataaaac cgagaaaaca cagcagtgtc actaagatcg aaatgaagac aatactagca
    26581 aaatagatcc ataattgtga aaatagcttt tttttcatct ttaaataacc gccttatagc
    26641 ctagtccccg tactgtgatg atttgaaaat cttccgtctt ttcaaaacgg gtccttaaac
    26701 gtttgatatg tacatcgatc gttcgttctt ctgtattcgt atctaatccc caaatatcat
    26761 ccatcaactg ttggcgagtg aagatcttgt tgggataaga cagtaattta tacagaagca
    26821 gaaattcttt ttgaggcaga atcaacgaat gctgatcttg taacactgta taagcatcta
    26881 gctctaattt tgtttgtccg attatcaagc tactgctgta attgatcttt gaacgtcgaa
    26941 gcaatgcttc cacacgtagg atcatctcat tgacatcgat gggttttgtc atataatcat
    27001 ctgctcctaa tttgaacccg cgtttcttat cctcaaaatc ggcctttgcc gtaatcatta
    27061 gaacaggtgt gtcaaatctg gtgctacgta atgagtctag caagtcatag ccatccattt
    27121 tcggcatcat gatatctgta atgattaatt ctatacgtgt cgcttctagt tttttcagcg
    27181 catcctctcc attcaatgcg gtgatgactg aaaagcccgc tcgttccaac acagaacggt
    27241 aaagcaactg taattgcgga tcatcttcta ctactaaaat acgattcatt gatctccctc
    27301 tgttttttga aaaatttcta gattttttct tgtagttcat cttcagttaa catttatttc
    27361 gtatactacg atcattgttc tgatatactt attagtatac cgaatatttc aatacgggag
    27421 aagggtgatt atgcttcaat taaaagatat aaaaaaatat tataaagtcg gcgaaaccac
    27481 caccaaagca ttggatggtg tgtctgtcgc tttcagacaa aaagaattcg tagcgatttt
    27541 aggtcctagt ggttctggta aaacgactat gctgaatgtg attggtggac tagataatta
    27601 tgattccggt gatatggtaa tcaacggaaa gtctactaaa gactttaagg acagtgactg
    27661 ggatgcctac cgaaacaact ctatcggttt catttttcaa agttacaact tgattggtca
    27721 tctaggcatt attgaaaacg ttgaacttgg gatgacatta agtggtgttt ctaaagacga
    27781 aaaacgaaaa cgggcagaag atgcattgca ccgagtcggc ttgacaaatc atatgcataa
    27841 aaagccaaat cagttatctg gtggacaaat gcagcgagtg gccatcgctc gagcactagc
    27901 caatgaccca gatatccttt tgtgcgatga accaaccgga gcgttagata cagaaacaag
    27961 tatccagatc atggaattga tccaagagtt atcgaaagaa aaattagtga tcatggtcac
    28021 acataatcct gaactggccc atcaatacgc agatcgaatc attgaatttt ctgatggtaa
    28081 gatcttaaca gattcccatc ctcacatcga acgaccaaaa gatgatcaat ttaacttacg
    28141 cagaacaaag atgagttttt ggacagcgtt aaagctttcc ttcaacaata tccgaacaaa
    28201 aaaaggacgt actttcttga cctcctttgc ttccagtatt gggatcatcg gaatcgcgat
    28261 cgttctgtcc ctttcttctg gattccaaaa acaaatcgat aacacgcaag ctgaaacgat
    28321 ggcgaaattt ccgattacta tttctaaggt aacgactaac cagactcgtg acgatgccgg
    28381 attgggtgca agcaaagcgg attatccaga cagcaaaacg attactgcaa aagtcagcga
    28441 agaagataaa gcacagcaca cgaataagat tgatcaaaca tacgtcgatt acgtaacaga
    28501 catcgatcct aacttaagta ataatatcgg atttacccgt actacaggaa tcaatctttt
    28561 acgtgatgta aatggcaaag tacagcctgt cagcttctcg aatcaaaatc ctgatacgga
    28621 atctctttct ttatctagta cgatgtcagc aatgacaggt gtgggagtgt caagtttccc
    28681 tacacagctt gacactagca aagaaaactt tttaaaagac aattattctt tacttgccgg
    28741 aagttatcca gcctcagcaa cagatgtcgt gctgatcgta gacggcaata ataatactaa
    28801 tatcaacgca ttgaagaatc ttggatttga tgtgaaagaa gacgaaaaac ttgattttga
    28861 tgatatcgtt ggtacaacat tcaaattagt aaacaacaat acttactata caaaacttcc
    28921 aactgggaat tttatcccta atacagatta tgatgcgatg tatcagaatg cttctgatga
    28981 attgaagatc tcggggatcc tacgcgtgaa atcttcttct acaatgaatc tcttatctcc
    29041 aggaatcgct tatagcgatc aattaacgac tcaaatcgtc aacgaaaaca aagaatcaga
    29101 aatcgtcaaa gctcaaagag acagtggtgt aaatgtctta actactgaaa aagttgacga
    29161 aaatgccaaa caaacattgc ttagttattt aggtggagac agcttgcctt caagtatcat
    29221 gatttatccg aacaattttg aagacaaaga aaagatcttg gattatctag atgattacaa
    29281 taaaggcaaa tcagatgaag ataaaatcat ttatactgat ttagctggaa cgatgactga
    29341 actgactggc ggattgatgg atgctatcac ttatgtcctt attgcttttg cagggatctc
    29401 tttagtaaca agtatgatca tgatcagtat cattacttat acatctgtga ttgaacggac
    29461 aaaagaaatc ggtgtactaa aagctttagg tgcacgtaaa aaagacatca ctcgcgtatt
    29521 tgacgcagaa acgtgtattt taggtatttc ttctgggata ttaggtgtgt ttattgcatg
    29581 gctagctacg ttccctatca atagcatctt atacaacatg acggatctaa aaaatgttgc
    29641 tcaactaaat cctgtccatg cgattattct agtgatcgtc tctactatat tgacgatgct
    29701 tggcggtcat cttcctgcac gaatggcagc gaaaaaagac gccgctatcg ctttgcgtgc
    29761 agaataaggt tgtgacaacc acatttagat ttgagtcata agagcgctga aatagtagaa
    29821 aacagcaaga aacgaggaag taatatgttc cttgtttcgc gctgtttttt ttaattattt
    29881 tttataattc tggtatactt ttctttcctt tgtaccacaa ctcttctggc gtatacctgt
    29941 cttttccatt tatgaatact gttccatctg cttcaatcgt tacttcagtc ccaatccaca
    30001 tattacgaga aagtgcgaga agattttttc tttttcctct tccttttttt ccaaattgca
    30061 aggcatcggt tatctcttct gtccaatgag atttcacgta ttttacttct ccgttttcaa
    30121 atgtaacttt caaaatattc gctatatttt ccacttttac tgctttagga aatgactcct
    30181 ccattttttt cactttcctt cctccaacac taagtatgcg ctttctttta gtgataagta
    30241 tatcatagtt tattctatta tcaaaaaaac gcatccattc cattgtagaa tactttaccg
    30301 aacaagttga attgttttcc tctttttcac cttttactat agataggtaa agacaactaa
    30361 ggaggaatct ctcatgacag atcaaccgta tgatttaaga aaagtcatcg aagaactaaa
    30421 aacacttcca ggtcaatatc acgaaacaga tattgaaatc gatcctgaag cagaattatc
    30481 tggtgtttac cgttatatcg gtgctggcgg tacagtaaaa cgtccgactc aagaaggacc
    30541 agctatgact ttcaacaata tcaaaggttt ccccggcaca cgtgtgaaca tcggaacaat
    30601 ggctagtcgt aaacgtgtag gtgaaatttt gcaccatgat tatcgaacac ttggtcgttt
    30661 cttgaaagac gctgtagaaa atccaatcaa acctgtgaaa gtagacaaag cagacgctcc
    30721 agcacaagaa gtcgttcatc tagctaccga tgcagacttc gatattcgca acattttgcc
    30781 tgcacctaca aatactcctg aagatgctgg tccatacatc acaatgggtg tagtcttagg
    30841 atcagatcca gaaaaaacaa tgagcgatgt aacgatccat cgtatggttc tagaagataa
    30901 agatacgatc ggtatgtaca tcatgcctgg cggacgccac attggtcact tccaaaaaca
    30961 attcgaagcc ttgaataaac caatgcctat cactatcaat attggtttag atccagcaat
    31021 tgccattggc acgactttcg aaccacctac cactccactt ggctacaatg aactatggtg
    31081 tgcaggagct ttgcgtaacg aacctattca aatcgttgat ggtatagcag tcgatgaagt
    31141 gggtattgct cgtgctgaat tcatcattga agcagaaatc atgccaaatg aaacaatgca
    31201 agaagatatc aacacgaact caggaaaagc aatgccagaa tttcctggct atactgggga
    31261 tgctaatcca gctgtacaag tagtgaaagt caaagcagtt actcaccgaa aagacaatcc
    31321 aatcatgcaa acaacgattg gtcccagtga agaacacgta tctatggccg gtattcctac
    31381 agaagcaagt attcttgcct tggtcgataa agctattcca ggaaaagtag taaatgtcta
    31441 caatcctcct gcaggtggtg gtaaattgat gaccatcatg caaatccgta aagaaaacga
    31501 agcggatgaa ggtattcagc gtcaagcagc tattcttgct ttatcagcct tcaaagaatt
    31561 gaagacagtc attttagtcg atgaagatgt tgatattttc gacatgaacg atgtagtttg
    31621 gactttcaac actcgtttcc aaggagataa agatatcatc gtgatcccag gaatgaggaa
    31681 ccatccattg gacccatcag aattaccaga atataatcct ggctctattc gtttccgtgg
    31741 gataagtgca aaaactatct ttgacggtac agttcctttc gatatgaaag aacattttgt
    31801 acgtgcaaaa ttccaagaag tagaagattg ggaaaaatat ttgaaataat gaatgatctg
    31861 caactgtttt gacatcataa aaaggagtgc ggaaaatgga acaattggca caacggaaga
    31921 aaaaaatcgt gattggtgta agtggcgctt caggcaccat ttatgccatc aacctagtga
    31981 agaaactaaa agaatatccg atgatagaaa cacacggaat catcagtcca tgggcaaaac
    32041 agaacttaaa gctggaatcc gacttatcac taactgaatt cgaaagcctg tttgattacc
    32101 attattcaaa caaagattta ggtgctgctg tcgccagcgg atcatttttg accgatggaa
    32161 tgatcatcgt accggcaagt atgaaaacag tcgcaggtat ctctgttggt ttaggcgaca
    32221 acctgattgc acgtgctgct gatgtaacaa tgaaggagca acgaaagtta gtcattgttc
    32281 ctcgtgaaac gccattaaat gccattcact tggaaaactt gactaaatta gcacgactag
    32341 gtgtgcaaat cataccacca attcctgctt tttataatca gcctcaaacg atccaagatc
    32401 ttgttaatca ccatacaatg aaacttttgg atcaatttga aattgtaaat gagcattcaa
    32461 aacgttggca gggtgattaa tatggaaaaa gaaacgatag ttgaagtaac caaactaggt
    32521 ttcacgatcc aagctgctgt taaagtaatc ggtaaagact tattgatcac tttaacaggc
    32581 ggagatacac cacatatcgg aacagtcact acattttctc gtgatacaga gatgcaaact
    32641 gtacgtttcc ctagccacga tggtcggttc cataaagacg atgtcttagc cgaaaaaata
    32701 gctgtgatca tcaaaactgc cgttccggga agttgtacga tcacttccgg tatccatgtt
    32761 gaccatatct ccaatgcaca aatcaacgcc tcttttccga tgtcagaaga gttaggttac
    32821 aagattttag attggttgga aaaaatagat ttccatatca aataaccagt ttattataaa
    32881 gatggtgaaa aaccattatg aaagaagagg ttgtgaaatc agcgttatga cctgagtatg
    32941 agagaaaaaa atggaaaaat agcttctcat attttgccgt ttttgagcta ataccgaggg
    33001 acagctgatt gaacgccgtt tatcaagagg ttgtgataaa gccgcttcgt ttcgagtagt
    33061 aagaaaaatt ttgtaaacat gggtttccac atttttgcat aaatttgact tactaccgag
    33121 aaactggctt ttgaacaccg tttatcaaga ggttgtgaca cgtcttttgt cacaacctct
    33181 tttatttttg cttcactgta actgctacaa tatcaccgat ttcttttccg atgtttttac
    33241 gaatatcttt tcgtagtcca aggatgtagc agactgaacc atctggattt ttcacgccca
    33301 tattcacgat actgccttca tacggcacat tgtcaaaagt tgcttggact ttaactcttc
    33361 cagcaccgaa ttcttttctt atatcatacg gaaaaataat atatgccccg cccttgccga
    33421 cttcggaagc atagattttt gattcaaaag aataaatttc cctcatttta tttctcctat
    33481 tttttacatc tagtatagca tagcaaaaaa aagaaggaac tgtgacaaaa gtcttgtcgc
    33541 agttcctttt ttcgaataaa cggtgttctc ctgccaactc ctcggtcaca agtcacaata
    33601 gtcaacaaac atgagaagct gttttttgaa attgctcctt gtgactcaga gttaaacggc
    33661 aggctcacaa cctcttcctt aaacggtgtt caaaagcttg catctacggc actaagccca
    33721 atcagatgaa aaatatggag tgctattttt atctgattgt tcttactgct tgatgcagag
    33781 cagctttttc acaacctcct acatggtgtt caaaatatta ttcgcctttt gcttctttca
    33841 ctaattttgc gaatgcttgt tgttggaatt cagcagctaa ggctttcgta cgttgttctt
    33901 gctctgcttt gctcattttt ggattttcag tcattgcttt taccataccg tcttgaacat
    33961 aagcttttgc ttcactttcc atcgtacttt gctgtttctt cactaattca gctaacttgg
    34021 ctgcttggtc cgtacttaat tctacccatg tctctgggat tttgaatgta ttcactcggc
    34081 tgtcatattc gtgattgtta tcagcaatat tgaaccagaa tttatacatg tcgtttttgt
    34141 attcccaata agtagttttc gtcacttttt cagcatcgcc gtctgtcttt tctactttat
    34201 ttgtttcgtt atccgtacca gttgcttttg gtttttcttg tttttcattt gttcggtaaa
    34261 gatacacttt ttcttttcca ttccctaaag ctttatacaa aagcatatct gctccttggg
    34321 aatcagcact ggaaacaatt ttttctgttt ttgtttccgt tactttttcc attccaaagt
    34381 gattggacaa attagcgacg atcaaactta gtgaagcgac gaagattagt ccgaaaatca
    34441 aagataaaaa ggtttgccat gtttttttag cgaacacgtt cgttaaagca aaagcaagca
    34501 agctgacaat caaaactcca ataatcatgc attatccccc gctttcatta gaacaggttc
    34561 ttttttcttc aataaaaagg caataataaa gccaagaatc ccaaagatga tcgctacgat
    34621 aaacgcggca tggtaacctg acagtgtggc attgattgcc tgatctttat aagctaatgg
    34681 cgtattatcc aatacagatt tgcttgggat atttgctttt gtcacattcg tcaacacact
    34741 gatcaaaata gctgtaccaa tcgagcttgc gatttgacgg aatgtattat ttaccgctgt
    34801 cccatgactg atcaagttat ttggcaatgc attcatacca gaagtcgtta ccggcatcat
    34861 gaccatggag atcccaaaca tacggatcgc ataaaggatc acgatatata aaactggagt
    34921 cgtttttgtc aagaaagcaa atggtgcagt tgccgctgtc aaaatgaaca tccctgtgat
    34981 ggctaaacgt ttcgcgccgt atttatcgaa aatcgcaccc gtcacaggca tcatagcccc
    35041 catgatcaat gcacccggca acaacatcaa gccagaatgg aatgctgatt ctccacgaat
    35101 attttgaata tacaatggta cgaccatttc tgcccctacc atcgccatat ttgttacacc
    35161 agctaaaaca gctgcaatcg tgaatgtaga tgatttgaat acacgaagtt ccaagaatgg
    35221 atgttccaaa tgtaattgac gccatgagaa caaggcgatg aaaatcacac caacaactaa
    35281 gaaaccaatt actttcaagc ttccccagcc gtcatctcct acactagaaa atccgtaaag
    35341 taaactaccg aatccaatcg ttgataaaat agcggataaa atatcaatgc taggatttga
    35401 caatggaata acacttttca ttaggaagaa tgctaaaacc aagacaagaa caacgattgg
    35461 cagtaccata ccaaacaagt cacgccaatg gtagttatca atgatataac cagataatgt
    35521 agggcctaaa gcaggagcaa gtccaataac gatccctgac atccccattg ctgatcctct
    35581 tttttctggc gggaaaatag atagcatgat attttgcaat aatggcatcg atactcccac
    35641 accgcaagct tggatcaaac gaccgattag taatgtacta aaattaggtg ctgtaaagca
    35701 agtaatcgtt ccgatcaaaa agatcgtcat ggcagaaaga tataaatttc ttgaactgaa
    35761 tttattgatc agccatgctg ttattgggat catgatcccg ttgactagca agaaaccagt
    35821 cgttaaccat tgcacatcag acgctgaaat atcgaaagct ttcatcaatg taggaaaagc
    35881 tgtcgtcaat aaggtctgat tcaaaacggt acaaaatgta ccaattaata agacaacaac
    35941 taaaagtgtc cgattatatg gttttccgta aatatctacg ggttggttgt tactcatatt
    36001 tctccttctt tctgaatttt ttctgaaact actagaatac tttagtccta aattcgctat
    36061 ttgtcaacct acttgacaca taagttaata cggatataat taagggaagc aagaggacaa
    36121 aaggagtgac aaaaatggtt ggggcttccc ttaaacgttt gttggaaaat gatcaattgg
    36181 ttgttggcat cagtgaatta agtgatatcg taggtgtgtc tccacgtcaa ttaaggtatt
    36241 gggaacaaaa gggattcatt cgttcgatcg aagctgatgc gaattgtcct agaaaatatc
    36301 gtttacctac agtcataaaa gtagaactga tcaaaaaata tttagatgac ggatttactt
    36361 tgtcaaaagc tgcagaaaag gcagaaatcc gccaaaagaa aatgcaccat gtccgtaaag
    36421 ttttttcaaa agcaatcaaa gatatcgaat tgatcgacga acgctatacg attttacaaa
    36481 tcggtaactt caaagaagag aatgctaaga tgtacatcat tcatgacaac gagacagacg
    36541 aattaactta caagctcctt cctgtcgatg aaaaagctga ctacgaacag ttgttaaaag
    36601 aactctaaac gccactaatc tcctaagtac caagcttttt aataagtaga tgctacataa
    36661 atacttgaaa aaaggcctgt ttgaacataa gaatatccga acggtgatct gcgtttcttt
    36721 catatagaaa ggaattctcc atcactgttc ggatattttt ttattttttt cggttacttt
    36781 cttctaatac atctgttagc caatttgcat attctgtttc ccgattgatc gcatgcgcta
    36841 aaatcaggta gtgtccgtaa ttttcatgtt tttctttttc agtaggaaag atcgtttttt
    36901 ttcgctctaa tagatgaagt cgtttttctt catgaaggtc acgctgctgc tgaataattt
    36961 ctactaatgc cggatcattc acgtctttga cgaaatacaa tttcagaaca aattcgtctc
    37021 gattaaccgg tagttcattg gtgggtgtat gaatccactc tgccaattgt tccttccctt
    37081 cttctgttaa ttcataaact ttcttttcca atttttcacc tgtgatctct acttgatgct
    37141 gaatgattcc ttgctcttcc atttttgcaa gttcaggata aatctgacta tgttttgctt
    37201 gccaaaattc tcctatttca tttttgaacg attgattcaa ttcatatcct gtcatcttct
    37261 tcttacttaa taaccctaac aaaatatatc gaagtgtatt ttttcttgcc atcagttttc
    37321 cctccttgac aaatctttaa atccattcta tcataaatga gtaatcgaaa acatgtagtt
    37381 tattacatgt tttaatttat aaggagatgc ttaaacatga aagaatttaa agaattggaa
    37441 gattttattg gaactcactt tatctatacg tatgacaatg gttgggaata tgaatggtat
    37501 gccaaaaatg accatactgt tgattaccgt atccatggcg gaatggtcaa aggccgttgg
    37561 gtaaaagacc aagaagctga tatcgttaaa ttgacggacg gcgtattcaa aatcacttgg
    37621 acagagccaa cagggacaga cgtggcattg gactttatgc caaatgaaaa gaaacttcac
    37681 ggaatgatct ttttccctaa atgggttgaa gaacatccag aaatcactgt tactttccaa
    37741 aacgaacata tcgcagaaat ggaagcagct cgtgaaaaat atgaaactta tccaaaatta
    37801 cttgttcctg aatttgctac gatcacttat atgggtgatg caggtataga caatgaagat
    37861 gttattagcg aagaaccata cgatggaatg ccagatgata tccgtagcgg aaaatacttc
    37921 gatgaaaatt ataaacgagt aaaataaggt tgtgaaagag aggttgtgaa atcagcgttc
    37981 tgacctgagt attagagaaa gaaacggaaa aatagttcct catgttttgc cgttttttga
    38041 gctaataccg agggtcagct gattgaacac cgtttatcaa gaggttgtga aatcagcgtt
    38101 atgctttgag taataagaac gctagttaga aaatagcttt tcatattttc taggctagtg
    38161 ggcttattac cgagaagcag ccgtttgaac accgtttatc aagaggttgt gaaatcagcg
    38221 ttttgacctg agtattagag aaacaaatgg aaaaatagtt cctcatattt tgccgttttt
    38281 tgagctaata ccgagggtca gctgattgaa caccgtttat caaagattgt aacaactgca
    38341 tattcacaca gttaaattag tgacttcaaa atgaaataat gctcccagca aaaaattagg
    38401 ctgggagcat tatttcgtta ttctgttcat caaaaatcag cgttttgatt ccatttcatc
    38461 acaagttcct cctcatttac tgcttcatct ttttgctgtg tttgaattgt aaaaccttgt
    38521 gaaagataga aatgaatagc tgattgattt ttttgataga ctgtcaaagt cagtgtttta
    38581 ttggtttctt ttattttttt cattagttgc gtaccgattc tttgttgccg gtattccctt
    38641 ttcacaaaga ttcctgcgat aaactgatca atcaccccag caaaaccaat aatttcttga
    38701 tctatttctg ctaagtaaat cactgcatct ggtaaagctt tcctaacaga ttctacttga
    38761 ttctcccaat aagttgatgg aatgaattca tgagaatcca agttagcatg cagccaaatc
    38821 gatagaacag attccagttc tttggcagac aattttgttg ttgtgcggat cattttttct
    38881 ctccttactt attcattgat tttaaaataa aaaccatttt tttgaagctc ttttacaagt
    38941 tttcgcccct caaaaaagta tatcttctct tgttttactt ttctaatacc aaaagaaaca
    39001 gcaactttag gatcatcagc tgaaacgatt cgataagttc caccaggcaa ttgatccagc
    39061 ttgactttcc catgatggtc gctttgtact gaaaacggca caccatttct agtaagtgtt
    39121 tttttcttat gtttcaaaat gaatgaacta ccatttaccg gtttccctga cgaatcacta
    39181 ataataaatg aaaaatcaag cactttttta cttaatctat actgatagat tagtcgtccg
    39241 ataaacacta acagtatgac tacagctatt atcgttcctg caagaataaa ccattgccgc
    39301 atggttcttt cctgatttcc ttttccttct tcttttttta ccgattcgtt ataaggaatc
    39361 cgatgtcctg tcactagcaa acgatgcgtg ttgatcatat acggcgtaca tgtaagcaag
    39421 gtaactaagt cttctccttc tgaaatcgtt agaacagacg tgtcatctgg cagtaccact
    39481 tgtatatttt taacttgata agccaatttc tcccccaaaa cagtcaaaat aaacgtgtct
    39541 ccgttttcta aacgatctaa ttcggtaaat aaccgtcgat taggtaaacc gctgtgagca
    39601 gagatcactg aatgcgtcga atttccacca agcgggaaag aggttccttg caagacgcct
    39661 gctccatttt caaggatcct accattgagc cgatcataaa gtgaaatatt taattggatc
    39721 ttaggtatat tgatacttcc gatcagccat tcctctaatt ggctggatgt tgtactttca
    39781 tttctgttct tttcattgaa aggatcagta ccaggattga atccttggtc agttaatcgt
    39841 tggtttttct cctccatttt ctttcgctgc acttcaattt cagctgcggt ccgtttttgt
    39901 acttgttcga tacgtttttg atcaataaaa ctatttaaag aatccacata aaatggatat
    39961 aaagcgatca gtaaccctac gacgatacat attaataaaa acaaacgaaa caaaagtcga
    40021 cgagactgtt tttgcttact ctgcttcaca tgtgtcctcc cttgcaagtt tttttgttct
    40081 ttcttttatt atatgggttc aggaaaaaaa tagaaaatga aagccgatga ggttgtgaaa
    40141 aagctgtcct gcatcaagta ataagtacag cccaaaaaaa tagctactca tattttttgt
    40201 tgggttgggc ttattaccgc agatgcaagc ttttgaacac cgtttaagga agaggttgtg
    40261 aaaactgcgt tatgctttga gtaataagag cgctagtcag aaaatagctt ctcatatttt
    40321 ctaggctagt gagcttatta ccgagaagca gctgattgaa caccgtttac cgagaggtca
    40381 tgaaaaagct actttgtttc gagtattaag aaaaattctg tttcaaaaca aggagatgca
    40441 acaaaactta tgtcgcatcc tctctcctta gaactttcac ttatgttttt cttgtaaaat
    40501 tcataaatat tttcatgaat tttctaattt cttgcctacc tctcgcatag gatatatgat
    40561 gaatttatct aaagtttgca aaggagttcg acaattgaaa aaatatggcc catttttagc
    40621 aatttttttc attgctttgg catttctcat gcctcattta ttcacacata aactaatttt
    40681 gggtgctgat gccccattcc attacaatcg gttctatgat gccgcgcaac aaattaaata
    40741 tggggatttc cattattttc cttcccttta tggattccag caaagtggca ggatcgtgaa
    40801 tgccgtttac ggcccatttt tcgcttattt acaaggattg atcgtgttgc ttgcaggtag
    40861 ctggtttcat tatcagattc tttcaaattt cattctttat cttatttcag gattttctat
    40921 gctgatttta ctgagatatg tcaatgttcg aaattgggta agtgtaccag tagccgtttt
    40981 attcatgagt acgtattcta ttcaatactg gtctatcaac caaggattca ctagctgggg
    41041 gacttgtttt tatcctttat gtatgatccc tattgctgat ttcgtccttc ataaaaagtt
    41101 ccctgttatc aaagtcgctg tctcagtggg acttatgaca cagatccatt tactgtcttc
    41161 gatcatgtta gctttgatgt atatcccttt ttatctttat tactttttta accagactga
    41221 aaaaggaaaa gcactgcttc aactgattaa gtcggtcttg ctttattttg ttctgacagc
    41281 aaatatttgg gcaggattag ctattgttta cagtgggaat aagattcttc ctccctttgt
    41341 taacagagaa atgagtcaaa aggcgataga tctggatggc agttattggc tccattaccc
    41401 taaggccttt cctatattga tattatcagg ttttttgctt tttattttct ttcaacaaaa
    41461 gaacacctta ttccaaaaaa tcgtgttgta cacaagtctt gttttctttt ttctttctac
    41521 tagcttgatt ccatggacga cattgatcga aaaaaatgtg ccttttatta gtttgatcca
    41581 gtttccattt cgatttttcg tgccatttac gctattgctt ctactttacc ttgccctttc
    41641 actgaaccag tggtctgaac aaaagtggtt ccgtctttta agtatatttg gcattcttat
    41701 tttttcagca cagacgatcc agaacttata ccagcatctg gaaaagtggg aaaatgaaac
    41761 atttgtcagt cgacatactt atctattcga tacgccggaa gaagcaagga aaacattctt
    41821 cagcaaagat atgtctacca gcttgttcgt tttccaaaaa accacacctg actatctgcc
    41881 aatctataag gagacaaaag acaataaata cgaccggtat aacgaagaaa tactagaaaa
    41941 cgaaacaact tttataaaaa cacatccagg cggtcttttg acaatcaagt ggaaaaacac
    42001 tggggacaaa actgttcata tccctgttat cgtctacgat cggactgtgc tacagcaaaa
    42061 tggaaaaaca ttgactgatt atgaagtaac agatatcggg accccaatcg tgaagcagca
    42121 aaaaggaatc aacgagctca cgcttcatta tcaaacgcca atctatttct atttcattct
    42181 ttctcttact ttgattggct ggtttacctt gctatgttta tttatttatc atagatacaa
    42241 gcttttacgt gcttaggcaa aagggataaa tacatccgat caaaaaactc tccaaacggt
    42301 ataatcgttt ggagagtttt attttaatca gtttttttat gttatatgtt atatttttta
    42361 ttcgttcaca tctaattcga tttccacccc gtagtgatca ctgatgattg gactatcgat
    42421 cccatcaaaa atccgttgat attttttaac ctgcattcct tcagggacga aaataaaatc
    42481 tatacgcaat ttttctgtat tttgttccca accatctatt ttcttttcca cagtagctgc
    42541 ttttcctttt tcattcgcga caacatacga atcttgaaga agaaggcaac tttctcttac
    42601 agtataataa ccttgagagt ctactggatt attgaaatca cctaggaaaa aaagtggtac
    42661 gcgagtttcc aaaaagtagt tttccaagtt tttccactca aaataaaagc cacttttttt
    42721 atctgtccac caagaaaagt ggcagctcga gacaaaaatg tcctgatcat ctatctttgt
    42781 tttcccaatc aagatcttgc gtgtctgata atcttctttc ttttgaaatt gggagacggt
    42841 aaggacctga ctttccaatg tttttttcgt aagcagtgca tttccttctt catatttatc
    42901 ataaccgatg tggctcattt cccaactcca aaaatactct tttccgtgtt cctttaaaag
    42961 ctgaactaaa cggtaggcaa aattatcttt acggataggt acttgattct ttaccggaca
    43021 gaacttcatt agcttcgcag gttctacttc ttcagattcc agtaattggt tgatttcttg
    43081 taaagcaatc acttcataat cttctaacag gatcttatct gctaattctt gcaatttttt
    43141 ctctggttct ggctcaagcc agctatgcgt gttgagtgtc atgaatttca ttggttttct
    43201 ccttgtcttc atttcgaaac aaaagggttg tgacaaaatt tttgtcacaa cctctccagc
    43261 aaatagtgtt ctcctgctaa ctcctcagta ataagctcaa tggaccagga gctatttttt
    43321 gtttggctgt ttttatcact tggtgcaggg cagctttttc acgacctctc cactaaacag
    43381 tattcaaact gctgcttctc ggtaataagc ccaaccaaac gaaaaatagg aggagctatt
    43441 tttgtttggc tgttcttatg acttgatgca ggacagcttt ttcacaacct ctccttacat
    43501 tttaatggag ccgatcactt taccagctgt cactgtacct aattgcttga tcactacttc
    43561 ttctacttta tcgtttgtaa atacgatcat gatcgttgga tctttttctt cgttttggat
    43621 cacatcaaga tccatctcag ctaatttcgt tcctgttcct acttcttggc cttctttgac
    43681 agcaatctca aaagctggct gattcatttg gactgtatcg attcccatat ggatcaaaac
    43741 ttcgatacca tctttcgttt ccagcccaat tgcatgtttg ctagggaaaa tacttgtcac
    43801 ttttccagcg atcggcgcaa caacttctct tgatgttgga ataacagcaa agccgtcacc
    43861 catcattttt tgtgagaata ccggatcttt tacttcagat aaaggaatca cttctccaga
    43921 agctgcggaa actagttctt gttctatacc taagtattgc ttactacctg cttgtccatt
    43981 tcctgtagaa accatttctg gctctggaat ctctgctcct gattgcagca gatcttcgat
    44041 atctgatttc aagacatctg cttttggtcc ataaactgct tggactccat tgtctttgac
    44101 gatcaatccc atcgcccctg ctcgtttcca ggcttcttca gtccctactt tttctcgatc
    44161 atttacactt acgcgtaacc gagtcataca agcatcgaca tctttgatat tttcttttcc
    44221 tcccagcaaa tgaatgatct ggaccacttg ctgatctgct gttcctgttc cgctgttaga
    44281 tacaacggtt tcttcactgt cattgtcgta atttccgtta cgtcccggtg tagcaaagtt
    44341 gaattttttg atcaagaaat ttgctaagaa atacgtaaca acaccaaaag cgatcacaca
    44401 caacacgaag ttgataagat ctccacctag acccgctttg atagctaacg gtgtccgagt
    44461 cagcaattcg atattcccaa atgaatggac ccgcaatggc aagatatctg ccatcgcaaa
    44521 tgcagcccct tggatcactg aataaatgac atataatggc acagcagcaa acataaacat
    44581 gaactccaat ggttctgtta cacctgttag aaagacagcc aacgctgctg aaaaatacat
    44641 tgatttatat cttgctttct tatcaggatc gacattacga tacatcgcaa aagccattcc
    44701 catcaagata cctgaagaac caatcatttg tcctactttg aaacgagccg gcgtccagtt
    44761 atgcaacaca aactcatatt gcgacatatc ccctgcacct ttaagattca ctaaatcagt
    44821 ggcccaagcc aaccataacg gatcttgccc aaatacttgt gtccccgcct gtgcgcctga
    44881 taaaatctca tacgatccgc caagctgtgt atagttgata ggaatcgtca gcatatgatg
    44941 caatccaaat ggcaatagta aacgttctaa tgttccaaat aaaaacggtg ctagaatcgg
    45001 tgcgctttct tgtgattctg caatccataa accaaaatta ttgattccag cctgtacgtt
    45061 tggccacacc acagcaagaa tcaatgccac gattgttgac cataagataa caacaaacgg
    45121 aacaaagcgc tttccattga aaaatgacaa agcatccggc aattttctat aattatagta
    45181 cttattataa gccattgccc cgacaaatcc agcgatgatc cctacgaata ctcccatatt
    45241 caaagctggt gcttccaata cacttgtaaa aaatccttta accatgatct tcgtaccgaa
    45301 cagagtgtgg gtaaatgcat cttcattcgc aagcatgtca cttgtgacac caaagatagc
    45361 cccagtgatc cgattgatta aaataaatga gatcccagct gcaaatgctc cgcctgctct
    45421 ttcttttgcc caacttcctc ctattgctaa agcaaataaa atatgaagat taccaataat
    45481 tgcccaacca atattttcaa ttactccgcc cgttgtgaca agcggcgtcc aatcaggatt
    45541 gatcaaggga attgatttcc ctatactgat catcaaccca gctgccggca taactgctac
    45601 cacaaccatt aaagcctttc caaatttttg ccaaaactca aaactaaata tctttttcat
    45661 tccgtttagc tcctttacgc aatcggtttc gttaaacgta ttatagcgtg cgttttcttt
    45721 tttgtaaatg ctttattttt tatttttctg tctataccat tctataaaac ctataatacg
    45781 tgtgttccct tctataattt tctcctaaaa atttattttt ttaagctttt ttctatgaaa
    45841 tattttcttt tgtctattga cttgtgcaat cggttgcgtt tattatgaac gtataaaaca
    45901 gctcattagg aggagaaaaa tgaaacagat caaacgacta tttgctattg atccatggaa
    45961 aatcagcacg acacaattag ataaaaaaaa tcttcgactg caagaatctt taacaagtat
    46021 tggaaacggt tatatgggga tgcgcgggaa ctttgaagaa acttactcag gggaccacca
    46081 tcaaggtact tatttggcgg gtgtctggta tcccgataag acacgtgtcg gctggtggaa
    46141 aaatggttat ccagaatact ttggaaaagt gatcaacgcc ttgaacttta tcgcgataga
    46201 tatttcgatc aacgatcagc tgatcgactt ggcttctttg gaaccagaag acttttactg
    46261 ggaattagat atgaaaaatg gtgtattatc tcgtacattc acaatcacta cttctactaa
    46321 taaagtacgc atttccttcg aacgttttct gagcattgtc aaaaaagaat cagcttatat
    46381 ctatttaact atagaaatgc ttgaaggtag cggaacagtc aaactcgtat caaaattgga
    46441 tggaaatgtt caaaacgaag acagcaacta tgatgaacat ttttggaatg agattgatcg
    46501 tggaactata gaagaaatcg gctatttgac gactaaaact attccaaaca actttgggat
    46561 tgaacaattt actgttactg cagcaatgcg ccatttcgtt aatggaaaat cagtcatccc
    46621 tgactatcac gaagatactt tagcattaca tggttgcttg tctgcagaat tatctcaagg
    46681 tgagacatgg tcagtggaaa aagaaattat cgttcttact agtagagata ttccagaagc
    46741 gcagcaagca gaaaaagctg tctcagaatt aacgaaccag acaaacaatt atatccaagc
    46801 aaaagaagag caaacagcgg cttgggcaga acgatggaag cttgccgatg tggtcatcga
    46861 aggagacgaa gaagcacaac aaggtattcg attcaatttg ttccaactat tctctactta
    46921 ctacggcgaa gatgaacgat tgaatatcgg ccccaaagga ttcacaggag aaaaatacgg
    46981 cggagccact tactgggata cagaagcgta tgctgtccct ctttatcttg ctttagccaa
    47041 acctgaagta actaagaatc tgctgaaata tcggcataat caactgccgc aagcaatcca
    47101 caacgctcag caacaaggat taaaaggcgc gctttatcct atggtcacct tcactggtgt
    47161 cgaatgccat aacgagtggg aaatcacatt cgaggagatt caccgaaatg gcgcgattgc
    47221 ctatgcaatc tacaattata cgaattacac cggcgatacg gaatatttga aaaatgaagg
    47281 actggaagtt ttagcagaaa tcgcacgctt ctgggcagac cgtgtccatt tttcaaaacg
    47341 agcaaataaa tacatgatcc acggtgtgac cggcccaaac gaatatgaga acaatatcaa
    47401 taacaattgg tatacaaata cgatcgcagc ttgggtcttg cgttacacgc gagaaaatta
    47461 tttaacttat caaaaagaag ctgctatcac tatcagcgaa gaagaactag ccaaatggaa
    47521 agatatcgca gagaacatgt acttcccagt tgacgaagaa ttaggaatct ttgtccagca
    47581 tgacacattc ttagataaag atctcatgcc tgtatccgat attcccacaa gcgatcttcc
    47641 tctgaatcag cattggtctt gggacaaaat ccttagatct tgcttcatca agcaggcaga
    47701 tgtactacag gggatttatt tcttcaatga tacttttaca aaagaagaaa agcaaaaaaa
    47761 ctttgatttc tatgaaccaa tgactgtcca tgagtcttcc ctttcgccaa gtatccattc
    47821 gattttagca gcagaattag gaatggaaag caaagctgta gaaatgtacc agcgaacagc
    47881 tcgcttggat ttggataatt acaataacga cacagaagac ggcttgcaca tcacttccat
    47941 gactggtagc tggttgtcga ttgtccaagg atttgctcaa atgaaaactg cccatgatca
    48001 gttgagattc gcaccatttc tgccaaaaac ttggaaagct tattctttcc atatcaatta
    48061 tcgcggacgt ttattgttca tctcagtcac agatgaacaa gttactttcg agttattaga
    48121 aggttctcct ctagaaattt acgtctatga acagtcttat tctttagcgg atcgtctaga
    48181 aataacgcta agaaaggagg aagcaaatgt ttaaaggggt attgtttgat ttagacggtg
    48241 tcattaccga tactgctgaa ttccattatc gtgcttggcg aaagcttggt caggaaatcg
    48301 gcattacgat cgaccacaca ttcaacgaac agctaaaagg cgtcagccga gaagactcac
    48361 tctctttgct tttagcttat ggcggaaaag aacactcttt ttcaaaggaa gaatttgcag
    48421 aattagcgaa aagaaaaaac gattattatt tagagatgat ccagacgatc gaaccaaaag
    48481 atgtcttccc cggggtcgtg cctttactgg attctttaaa agaagaaaaa atcaagattg
    48541 ctcttgcttc tgcaagtaaa aacgggccat tcctacttga aaaaatgggt cttacacctt
    48601 actttgatgc tattgccgac ccggcagaag caacaaacgg aaaacctgcg ccagatatct
    48661 tcctccttgc agcaaaagct gtcggactaa aagcagaaga atgtatcggg atcgaagacg
    48721 cgcaagccgg tatccaagcc atcctctcaa gtggcgctca accaattggc gtgggacgtg
    48781 ctgaagacct tggagaggag atcccgcttg tccctgatac gacttttctt acgatcgatt
    48841 acttgaaaga aaagtggcat gaccatggat aatccagaga tctccgtcgt accagttcca
    48901 gagactgaaa taaagaaaat cacattgaag aacgactact tagaagtcgt tcttctcaat
    48961 tacggtgccc gcctgcacca aatcttcgca ccagacaaag aaggaaaatc agaaaatgtt
    49021 ttattgtctt acgatcgttt cgaagatgtt ctaacagaca aaagcttttt tggagcaact
    49081 gtcggacctg tagccggaag gatccgggat gcttcttggg gtgagcatag attggagaaa
    49141 aactgcggat cacaccatat ccacggtggc acgaaaggct ggtctttcca attttgggaa
    49201 gtagaagttt tcaaaactcc atcatcaata ggtgtggtct tttacttaaa agatgaattt
    49261 tctacctatc caggaccaat cactgctacg atcacttacc gtttaacaaa aaacgaatta
    49321 gagatgacaa cctctgctag tagccttgtt gaaaccatct gcaatccgac caaccatgcc
    49381 tacttcaacc tttcaggaaa tggaacaaga gacatctatg aacatcagtt aacggtcttt
    49441 ttagatggtg tgcttgaatt agatcaagaa aaactgccta ctggaaattg gacaaaaaaa
    49501 gaaaaactgc caatcgactt tagaaaatcc ccaacactgc aagagatcct tgcatgttat
    49561 ccagatggac tagatgatgt atttcttttg catcatccta ggctttccaa aacttcctta
    49621 caattattcg agaagcattc tggtcgccaa atgactatag caacttctaa taaaagtatg
    49681 gtattatttt ctacgactgg attcgaagct gatttctctg tcaatggaaa acagatgcat
    49741 tcaaactacg gattagcaat cgaaccgcaa gaaatccctg atatcgttca tttccccaaa
    49801 tttggatcga tcaacctcca tcctggtcaa gaacggatca gtcagacgat ttatcggttc
    49861 tctgcacaat aacaagagaa aggtgttttt atcatggcta ttaccgtaaa agatgtggcg
    49921 aaaaaagccg gtgttgccac ctcgaccgtc tctcgtgtca tcaacgatca tcctagtatt
    49981 tccgagacaa caaagaagaa agtccgaaaa attatggatg aactaggtta tgttcctaac
    50041 atgactgccc gcaatctagg aaaacgcatt tccagtgcca tcggcgtaat cttaccccct
    50101 cttgattcaa aagagcggat cggtaaccca ttttatcttg agatcatgga agcaatcaac
    50161 gaagaagcgc ggaattatga tatgactaca gcaatcgcta ctgctaaaaa ttttgaattg
    50221 ctgttagaga acgtccagcg tatgcattta caaaaacaag tagatggttt tattctagtg
    50281 tattcagata gtcaagatac tgtcattgat tatttatacc aaaaccacat ccctttcact
    50341 ttgatcggac agccttatca tcatgagaac gaaatcgttt atgtagataa tgataaccag
    50401 cttctaggta aacaagcaac agaatttttg atccagaatg gacataagaa tatcctgttt
    50461 gtgacaaaca cgactcatga aagtttgtat ttcgaacgat atttcggtta tcaaaaagca
    50521 atgatgatgg ctggtcttcc tgcgttatcc agtgtagtac tagagcatcc ggaggattat
    50581 ctgtcctttg agaaaacgtt gaaagaaaac gaagccacag cattggtggt cattgacgat
    50641 atcttcgccc ttcgcacgat gcagttggcg caaatgtatg gctatgtcat tccagagaca
    50701 ctctccgtca ttagcttcaa caactcgatc ttctcaacat taacacaccc ttaccttaca
    50761 agtatcgata tcgatatctc cgaattagga cgtgtcgcta tgcaaaagct gcgcgaattg
    50821 atccatgaag aattgagcag tggcgtacgt ttggtcatcc ctcatcgctt gatcaaaaga
    50881 gagacagtcg ttcctttaga aaacccatac taaatagctg actcactaaa tacgctgacc
    50941 atttatccta tggtcagctt tttatgtaaa agaagatact acttctaaca cattgtttat
    51001 ctgtaaaaaa gagcgtggga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt
    51061 ataaacggcg gaagcagaag caactccttc ggaaataagc tgaaattcac aaaaatttaa
    51121 aaagcaattt tcttgagttt cttcttattt cttggagtta aacgcttctg tcccagcctc
    51181 ttttttcctt ccttcaattt tttacacgtc gacgattcaa taaaaaaccg cctaatattg
    51241 taaagacagg tgcaagaatc gagaaaaagg cgaatggcaa gtaatgcaac gcgctaactt
    51301 tcatcgttcc cataatgaat gtgccgctga ctccccacgg tacgagagaa ttgacggtcg
    51361 cacctgaatc cgctagtgtt cgtgtcaaat aggtttttga taagccaacg tcatcaaaag
    51421 aacgcttgaa tgtttctcct ggaagaatga tggacagata ctgttctcca acgatcagat
    51481 tgattccgat acagctcaag gcagtaaacc cgactaaacg agaaggtcgg tccatctttt
    51541 cttttaattc ttgaacgatg gtatcaacga tcagatattt gatcagtaac ccacctaatg
    51601 ccaatgcaag taaaatcaaa ctagcagaac ctaacatact catgatcccg cctcgagaaa
    51661 gcagttcatc tagctttgga tcaggtgtat ttgcgacata accattcatc aagatgtctg
    51721 ctgcttttcc gaccgtcaaa cttttctcat ggataaaaga aagaacgaga gcagctgtcg
    51781 atcccgctag taatgtaggg atagccggaa tttttttgat tgccccccca aataaaataa
    51841 ctagtggaat caatgtccaa ggagagatcc aaaagctcgc tttcatgttt tggatcattt
    51901 cattgatact agctagatcg gctgaatgac tgttatgtcc taatatcgta taaaaaatca
    51961 acgaaaggac gaatgctggg aaatccgtat aacgcatacc agcgatatgt tcgaatagat
    52021 taactcctcc aatacccgct gccaagttgg tcgtatctga taaaggcgag cagttattcc
    52081 ctaaaaaggc accggaaacg actgcgcctg tagtcattgc atcattgaat ccaagtaaat
    52141 gaccgatccc caaaaaagca attccaatcg tcgaaatcgt tgtaaatgaa ctgccgacag
    52201 tcactccgac aattgcacaa acaagaaatg ctgtcggtaa aaagaaacgc acagaaacaa
    52261 gtttaaatcc ataaaccata atcgtaggga tggttccaga taaaatccat gaagcaacta
    52321 agacaccaat caaaagaaaa atcaggattg gaatgatccc tggagtgatt cctttgatga
    52381 tcccgtcatg gatctcatcc catgtgaact ttttaaatct gccataaaac aacaaacaca
    52441 tgaaagctgc aaggatcggg atatgtggcg agagctggaa tccgatgatc agtactccta
    52501 ggagtgccaa caacacgatc aatacagcga tactttcttt taaagaaata tttttattca
    52561 tcgtcgatct cctatttcaa atgaaaaggc cctgccatga aaaaactatt cacttggcag
    52621 gacctcctac taaatcagcg acaaaacgtc ggctgaaaga cttatttttt tatttttctt
    52681 ctaaactttt ttctacctca atcccccaag aatctttctt gaagtgattg atgatcaatg
    52741 gaataacgaa catgaccact gtgatagctg ctactaataa tgcatcactc aatgtcgctg
    52801 tacctaatgt agcaaatacg acaacgatga tagagaagat cagcatgcag ctgactaccc
    52861 aagctaatcc gtttccgttt ttaccaattc ggtaaggacg ttcgaattct ggatgtttct
    52921 tacgcatttt aagcaatgaa acagcaatca aaatgtacac gatacaataa ataacagttg
    52981 tagcatttgt aagtgtcaag aatacagcac ttacgtcatc cattacacca taaagcaaag
    53041 caaataatga aataacgatt gattgtgtta gaacgacatt tctagatacg ccgtatttgt
    53101 tttctttatg gaatccgaat tttggtggaa ggaatccttc acgagctact tggatgattg
    53161 tttttgatgg tccagtaacc caagctgata attgtaaaag cacaccaata aataccatga
    53221 agctgaagat atttccgatc acttctggta agcctaggat ttgacagtca atcaagatag
    53281 gctgcgtgat atttgctaat tccatttttc catctggtac gacatttgct acaagcatcg
    53341 cattgatgac attcaataaa actaatccga tcaaagcgat aaatacgcct tttgtataat
    53401 tttttgttgc gtctttcaaa cgaggcatgt aaacagaact catttcgatc ccaacaaaaa
    53461 taaatgtgat accagctaag tatttcaatg aatcaatatg ttccaagtca gggaaagctt
    53521 ttgaccatga aaagtcacct agatagccgt ttgagactag tccgactttg aaggctgcca
    53581 aaacacctaa aacgaacatg atgactactg ggatatatac ccctagccat acaccgatgt
    53641 tcccgccgac ttttgccata tcgaatttca agttcaagat cgtgatgatc cagtagataa
    53701 ctaaaataca acctaaaacg aaccagtgat tattgccaag ttctacatta ccaaatgtgt
    53761 ttcctaacaa tggtcctaaa gtagaagcga ccattaccat acctgggaac atttgcaccc
    53821 ataatagcca tgcaacgaca aatccccatt tgctgcccag tgctgttttt acccataact
    53881 gaggaccgcc ttcttgagga agcatcgtgg aaagctcacc ggaaaccatt gatatcggac
    53941 cggcaaaaaa caaaactgca aaaattgaat aaaaaatcaa tgtccaaccg actgcggcta
    54001 acgtaggaat actccgaacc gttgcacaca gtgccattgt cagaccgata aaggtcccaa
    54061 gacccatttt acttacttca gatttactca ccgttgacac tctccttgat tttttggata
    54121 aaataacggt gtctttgaag tagtttcagc aataaacgaa acaattcagc gaatatttga
    54181 ggggattctt tgagtttatt gcttgaaggg tttcttcaaa gacaacctca aaacaaaggg
    54241 atcgaagagc ttaggtctcc ccttgctctt cagatccaaa catgcgtcag aaacagttag
    54301 tattcaagct gttttctaac atgattacct tgcttatttt gcttcgcttg ccaataattg
    54361 gtctgcgtag attttttcca atttttcttg aagagctgct ttgatttttt cagcatattc
    54421 ttcaaagtgt tcttctttgt tcatgtatgg tgtcattacg ctggcacgca atacagttac
    54481 ttttccggca cggttccatt cttcatctga gaatcctagt tggttcacaa attgtaatgg
    54541 gctgttgcca tagtctggga tagcaaagtc agtatgtgaa gttaagaact cattaccgta
    54601 aatgcttcct ttcacgtatg aagaataatc atatacgtca tggttcaatt tattcattgc
    54661 aactaagtca tcgttgcctt tttctttgaa tacatagtct accatattga aatctggata
    54721 agttaatgga tgaacttcga tttctttgtc tcctacttta aatgacaagt cattcaagaa
    54781 gttgtagaaa cgatgtgcac cttcgattga tgcacccatt aatttaccat atcctgtgac
    54841 attcaaaggt aagacatggt gtgctgccca aacgctggct gctgttgccc ctgcttttga
    54901 accttccaag atataagccc caagtaatgc tgggatatct gcgccttttt caaatacata
    54961 tgtcgcaaag taagagataa cgtctctcat gcggatatct ttgatgacga taccaccggc
    55021 agaatatgga acatagccca ttttatgtgg gtcaatcgtt acagattctg cttcttcgat
    55081 tgctttatat gcactgtgta cttcttctaa gatataatct ttgttttctg taaagacatt
    55141 gtatttgtaa tgaacatctt ttaaatcttc aaatggaatg aagttgttgt cttcgtctaa
    55201 gaaaatcgca cggccgtatc cgccataagc agcatctacg tgtaagtaga agtaaatacc
    55261 gtctttttct aatacgcgac gcaatgcaac gattttatcg ataccgtcga ttgctccttc
    55321 ttctgttgat cctacaacac cgactacacc taggattggt gttttttcag ctgctagacc
    55381 acgaacgatt ttttcaagtt cgttgatgtc catgcgatag ttgtggtcaa ctggcactgg
    55441 aatcacttgg tctaaaccga taccgatgat gtcggcagct tttagccatg aatagtgttt
    55501 agtttgtgga accaaccatt ttcctaattt ttctaaatgt tttccgctac gtgctgagtg
    55561 agctttgatt tcgtcgattt tttctgggac gctgtctaac agattcatga tttcttctgt
    55621 tgacaagttc attaattccc aatcgctttt tccagcaact agttcaggtg tcacttcttt
    55681 cattgcaagc ggcaatgatt tgatgttgcg ggcataccaa agtccttcta agtttgctaa
    55741 agaaccatca gcaacgatgt ggccccagcc atctttatag ctcattaatt ttgcaaattc
    55801 cattcctact tcttcttcca tttggcttgt tgcaggagaa gattcatagg caacgttatt
    55861 accattccat agcatagcaa aattgtacgc tagtaaagat ggcatcaatg tttcagagtt
    55921 catatgaccc cagtaacgtc cggcattatg ccaaggaacg gaatgggtac gcatccgcgc
    55981 tgaaatttct gatagaacat cctttgtttt attcacagtg tgttcaaaac tagcactgct
    56041 tttttcttct ggcgtaataa taggcatgtc ttgaggcatg tagttttgac gccagcctaa
    56101 atgttcatcc accaattcat tcaacaaagc tttatagatt tggccgttct cagctttgtc
    56161 cccaatgaat agggcattta ggtttagatc tttcgacaat gattcactca tagtgaaacc
    56221 ctcctaaaaa aatatttaaa ttttgtcgag ccctacatta cacctgttct tctattctgt
    56281 aaactaagtt ttggcctgat ttttaatcat attttaatat gtatcaatta tccgaattgt
    56341 tcacactttt gaaataatta aaaaaaacga gggaatttac aaatgtaaac tccctcgcaa
    56401 agattgtatt aacgacaacc agcgttctat tttaggatgg gtttcaaaat tggaatgttg
    56461 taatagtatt tccctttttc aaggtaaaaa cttactaaat tctaatcaat tactttggcc
    56521 aaaaagtaat ttttcttacc ttttcgaata accacaaact taccatcgaa ttcatcggat
    56581 ggatttatga caaaatttaa atcggtaacg cggtcaccgt taatacttat agctccgttt
    56641 gaaacatctt cacgtgcttg acgtttagat ggttcaattt ttgtggaaac aagcagttcc
    56701 acgatatttt caggtgtgct tgaaatttca acgttcggca ttttaccgaa tccttgcgcg
    56761 atttcttccg catttagttc tttaatattt ccagagaaca atgcttgcgt tattttttgc
    56821 gcttctttca agtcttcttc actatgcaca aatcttgtaa cttcttctgc caaacggcgt
    56881 tgtgcttcac gtttctcagg ttctgtctct acttttttcg ctaagtcttc gatttcttct
    56941 tgagacaaga aagtaaagaa tttcaagtat ttcactacat cgcgatcatc ttgattcaac
    57001 cagaattggt agaactcaaa tggtgaagtt ttcttcggat caagccaaac ggcaccgcct
    57061 gcagtttttc cgaatttcgt tccgtcagcc ttcagcatca atgggatcgt taaaccgaac
    57121 gcttctgctt ctggtccttc taattttcgg attaggtcta atccagctgt gatatttccc
    57181 cattggtctg ctccaccgat ttgcaattgc acatcgtatg ttttatgcag atgcaaaaag
    57241 tcgatagatt gcaggatttg gtaagtaaac tctgtaaatg agattcctac ttccaaacgg
    57301 ctggcaacga tatcttttgc taacatcgtg ttgatgttga agtttttacc gtagtctctc
    57361 aaaaattcaa gtaaagagat ttttgacaac cagtcgtagt tgttcacaaa tgtgatattt
    57421 gcatctttac caaacaattt tctcatttga ttggaaagtg cgtccacgtt atgttgcact
    57481 tgttccatcg tttgcaacac acgttctgtt ttgcggccgc ttgggtcgcc gatcgttcct
    57541 gttccgccgc caatcagaat atatggatga tggcctgcca attggaatct tttcatcatc
    57601 ataaatggaa tcaaatgtcc gatatgcatc gaatcaccag ttggatcaac gccgcaataa
    57661 agtgaaatgc tcttttcttc aacgagctcg cgaagtcttt cttcgtttgt ttgctgatta
    57721 atggcgtcgc gccaagttaa ttcatcaata atattcattt tactgacctc cgtgtagttt
    57781 ttttatgaaa gcaggaacct gctagcatat gtaattaatt atttcttcag gataggatag
    57841 gaaataaaaa aagtcccttg gcatataagc caagggacga aatctcgcgg taccacccaa
    57901 tttgtatgtc tagatatcca acatacctct cgaacattta acgctgtcgc gtggcaatca
    57961 ctgccaaaga ctcctgaaat gtaattcgct ttaaagcatg tactggtttg cagcgaccac
    58021 cagctttctg aaacattggc tttaacaact acttcgtttc gatcttcgtc ttgttattat
    58081 taatatgtgt ctatcataga gcgcaacttt ttctttgtca acagaaaaag gatatttttt
    58141 ttaaattcct cattttttct tttttgaatc cgctctaatt ccgaacattt tattttcaat
    58201 tattgttaaa agaaataact ttttctgtat tttttctgca atttatcgag aagtcacttt
    58261 actttgcctc ttattctttc ttcgttacaa taaggaatgg gacaagtaaa aaaatgaaaa
    58321 agcaagggac gaggtatatg gaaaaaaagc aaaaaattat tttaggagcc acttctgctt
    58381 taactatcgt tattttaatt ctaagtttgt tttttgtcat ccgatcatct acaaaaaaag
    58441 aaccaatcat tcctgaaaaa aaaataacag aaaaagcaaa agaaccgaca gatgataagc
    58501 aacaactagt tactcaagca aaaaatctgg ctcaaagcta cgattatgac caagcgattg
    58561 cgttattgga aaaagatagt aagaacggat ctactgaaac acaacagctt cttcaaacac
    58621 taaaaaagga gaaagaacaa ctgatcgact ggtctgatcc tactcagatc tctcatgtct
    58681 ttttccacag cttgatcgtg gacccgcaaa aagccttcca ctctcaacag gcacaaggat
    58741 acaaagatta tatggtgact gttgaagaat tcaaccgttc gatcgaacaa ctttatcaaa
    58801 atgattttgt tttagttaat ttgaatgatt tgatccaaaa agacgaacaa ggaaatcttt
    58861 cctttaacgg gcttgcgcta cctgaaggaa aaaaaccatt ggttctttca caagatgatg
    58921 tcagctatta tgaatatatg gataattccg gttttcctag ccgattggtc gtatcaaata
    58981 acaatgaaat caaaaatgtc tataaagaga aagataaaga agaaatcggt gactttgaca
    59041 tggttcctct gatcgatgcc tttgtcaaga aacatcctga tttttcttat cgaggcgcaa
    59101 aaggtacctt ggccctgaca ggttacaacg gagttttagg ttatcgaaca tcaaaatctc
    59161 aatatggaga caatgaaaaa acaaaaaaag agattaaaga agctaaaaaa gtggcggaac
    59221 agttgaagaa agacggctgg agctttgctt cccatacatg gggtcacttg aatatgactc
    59281 aagcttcact agaagatgta aaaaaagaca atgaattgtg gcagcaagaa gttgcaccta
    59341 tcctaggaaa aacaaatatt ctgatttatc catttggtgc agacatcagc gactggcagc
    59401 cttattcagc agaaaatcaa aaatttgctt acttgaagag tcaaggtttc gatattttct
    59461 gtaatgtcga tgcttctaca ccagcttggg gacaattagg tacggatttc tatcgaaatg
    59521 ctcggatcaa tatcgatggc attcgttttc aatctgattt agacggaaaa aatcctattc
    59581 ttgatccatt catcaatgtc catgatgtct atgacaaaga agcacgcgaa tctgcttgat
    59641 tttacgtcat ttatgaacca aaaaagccga actgacattt tatcgtcagt ttcggctttt
    59701 ttatgcttta tttcttcttc ggtgcgattc ccttgatcag gacttctgtc cattctgctg
    59761 tatatggaag cagttttgcg tatatctccg gcttagaaat tccttctacc attgcttgaa
    59821 aatagaggat caagaactca tccgaatatt tcaaatccac ttttccttct ttccgccctc
    59881 gatggaaaag atcaagcatg atactgaaac tttcttgcgt atacgcatcc atcgcgtcag
    59941 aaaattcttt tttttctttt tttgtatagt atgtcatcaa atcgatataa aattgtttgt
    60001 tcactcgatt gagataacgg attttgtttt cactcatggc aatcagtgtt tcttcaaatg
    60061 gaagattttc cgcaatcaac gctttcgctt cttgccctaa atcattcata aatgcaaaaa
    60121 atacttcata aatcagccct tccttgctgc caaaatattt aaaaatcgtc gctttactta
    60181 cctgagcgtt ctcagctacc ttatccattg tcactccagc ggttcctatg tctgtgttca
    60241 tcaagtcaaa agctgcttgt aaaatctctt tctttttctc ttgtgctctc ttttcaaaac
    60301 cgttcatttg tagagcctcc cgtaatttta aacttttata atatatatag ttcaaattta
    60361 ttctgaggtt tattataact atctattgag aaagtatcaa gctagcaatt ccttgtttat
    60421 gaattcattg acagaaattt ataaaaagaa tattatgtac taaaataata aaaaaagttt
    60481 tataaaaagg tataaaacct ttttattaaa ctatttaatc ttgtttagta tatattttta
    60541 gaaaaaggag tggggttttt atggcagaaa tcgtcaaagt cacacatttg aaaaagagct
    60601 ttggtcgttt cgaagcttta aaagatgtct ctttcaccgt acattcaggt gaagtcgttg
    60661 gatttatcgg accaaatggt tctggaaaat ccacgacgat tcggacactt ttagggatta
    60721 taaaaaaaga cggcggaacg gcaacgattt ttgggcaaga tgtatgggaa gatagtttat
    60781 ctatccatga acgtctttct tatgttccag gcgatatctc tttgtgggga aatttgactg
    60841 gaggagcgat catcgatctc ttcatgaagc ttcatggaaa agggagtgct caaaaaaaag
    60901 atgaactgat tcaacgtttc tctcttgatc ctaagaaaaa agcaaaaaac tattcaaaag
    60961 gaaatcgcca aaaagtgggc ttgattgctg ctttggctgt tgattcggat ctctatttat
    61021 ttgatgagcc tacttctggt ttagatcctt tgatggaaac gattttccaa gaagaagttg
    61081 aaaaattgaa agaacagggc aaatccatcc tactttcttc tcatattctc agtgaagtcg
    61141 agcgactagc ggataaagtc gtgatcatac gcgaaggaac actcgatgaa gaaggaacac
    61201 tcgatgaatt gcgtcatttg actcgttcga ccatcactat agaaacagaa gcagagaata
    61261 gtcacttagc acaattgaac ggtgtccatg actttgtgca aaaaggtcac ctcgctcaat
    61321 ttgctgctga taacgaagct ttcgatgtga ttttagctga agcgtccaaa ttaggtgtga
    61381 aaaaatttga atctattcca ccgactcttg aggatttatt catgagacat tatgaaggat
    61441 gaggaggaag cgaaatgact gataaatttt cacgctggtc cacccttttt tctcaaaacc
    61501 ttagccgtga ctggaaaaag atcctgatat ggctagtcgg tgtcactgct ttttctggtg
    61561 gttttgtccc tgcgtttgaa gaattgactt ccggacaagg attagctgga ttatacgaaa
    61621 ccttgcaaaa cccggcaatg attgcaatgg tcggaccaac tccagcttcg aatgctgctg
    61681 agtatacttt aggagcgatg tatgcaaatg aaatgttgct tttttgcagt ttgtttgctg
    61741 ctgtgatctc tgttttacac gtggtgagcc aaacgagaaa aaaagaagaa cttggtctga
    61801 ttgaacttat tcgttccttt cgagtcggac gtcaagcaaa ctctttagct gtcatcgctg
    61861 aaagtattct gatcaatttg cttttagcaa tatcgatcag ctgtacgatg atttttttcc
    61921 aagcggattc gatcactgca gaaggtgctt ggctttttgg gctatctgta ggtagtatgg
    61981 ggattttggg gagtgccgtt gcactgtttg ctgcacaact gatgccaagt tcagccagtt
    62041 cgaatggtct gtctttagcg tttttaggtg gactttacct tctacgagca ataacagatg
    62101 tagctgattc ctccctttcg atgtggaatc ctttaggctg gtcttatttg acctatccat
    62161 ttacaactaa caactggatt cctttgcttt atttgttttt gttcagtcta atcttgataa
    62221 tcagttcatt tgttttagag gaacatcgag atttgaacac cggctatatc cccgaacgtg
    62281 aaggaaaacc gtatgctaaa cgttctcttt tatccttgcg tggtttatta ttctatctaa
    62341 ataaagggat gacaatcagt tggcttatca cttttggttt gatgggggcg gcatacggct
    62401 ctatctacgg gaatatgcaa cagtttttag aaagtaacga cttaatgaaa cagatgttta
    62461 tccaatctgg cgtctcaatt gaaaaaaact ttacaagcac gatcatggta gtcttgattt
    62521 gtctagctgc tattttacca attgctagca tcaatcgttt atttacagaa gaaacccacg
    62581 gacgtatgaa tcagctgttc gcaacaaaaa tttctaggaa ccaactttat tggaccaata
    62641 tgttactagc tattctattt gctatattgg caatcctgat tagttctggt gcactagggc
    62701 tttctgcttt ggcttcgatg aaggatgcga aagacatgga tctattgatg tttcttaaag
    62761 ccgggttcaa tttcctgcct gccgttttag tgtttatcgg aattagtggc tttctattcg
    62821 gatggcttcc tcgaatcggt aaacttgctt atatctactt agcttactcc tttgcactca
    62881 attactttgg cggaattttg gatttaccag aatggttttc caaaacagct gtccctagct
    62941 gggttccacg gatgccaaac gattcttttg atctttccgt gttccttacg ttatcatgta
    63001 tcagccttgc actgttcgtc cttggttcta ttggttatag gcgaagagac ttactagaag
    63061 gataataaaa aagcatgtac aatttcatgc tagcctccaa atctgggtca aaaatccaac
    63121 atttggaggt cattttttta tttacaagtc ttctaactgc tctttatcaa tgatccagac
    63181 ttctcgattc tttcttttta cataaccatt ctcctctaat aatttaaatt ttctagataa
    63241 agtttcgggg gtcgtaccga taaatgcagc aagttctttc attttcattg gcaggaaaaa
    63301 gtgatccttc cctgtcgctt tagctaagtc aagcagatag agagcgactc gttcttctac
    63361 tttttccatc atcaaaaaag ttgtctgctg ctgtactttt gttaatttct caacgttgat
    63421 tgctaaaagt ttcagactaa gggcgggata atgcagtaag agttccgaga aatctttttg
    63481 tctcaatatg caaatttccg ttttttctag tgcttcgcca aataaagact catttggaac
    63541 gcctagcaac tggctctctc cctcatatcc gcccggctct attactcgta aaagctgttc
    63601 ctttccgcta gcagataatt gatacacttt catactgccg gaggccacga tcactaattg
    63661 aggttctcca ttcggcgcaa gaatctgttc tcctttttcc acatagtgat gtttgacaag
    63721 tgcgtgtact ttttcttgat cttgctgtac taagtgattg aacaaaggaa caaatgaaac
    63781 acataaatga tcatgactca taatctctcc tccttctaaa cagctatttc taataaagaa
    63841 acataacttc ccttattcca actgataatt ttcttttatc atagcataaa cgtcaagcga
    63901 accagatacc agcaaataga gtggatttct ttttgtccct tgctttattt tccttctttt
    63961 gagaccttaa gtaattgatt cctatcaatt ttttaaatat ttactttttg aataatcaaa
    64021 aacaaacctt cactcgcaag ccgagagtaa ggtttgtttt tcgcattgct tatttcgtgt
    64081 tgtctattga aatttttccg cacctagctt ttgatatagt ggtgctagtt cttgtaaggt
    64141 ttcagcggtt atttgctcaa cgtgttcgat ttcttgcgga tagaagaata gtttacccat
    64201 ttgaaaggtt cggtctctca tcgctttttt caactcttct tgtttctttg tatcggacaa
    64261 atagtcagac aaagctaagt ggtcgtcaag ttcatgttct ggttgcggcc atatgtaata
    64321 atccttgata tcgactgttt tgctccactc tttcagtatc gcaagcaact ggttatacgc
    64381 tgcaatgcta ccatatcgtt cttcgctttt ataatgttgg tacatcaaat agatttggta
    64441 ttgtttttga ttcaacaaaa ctgctagaca ggcattctcg tcttgacgag attcgcttcg
    64501 gtacgcgctc caaaaatgac tgcgtaaatt ccagccattc gtccagcttt cgattttagg
    64561 tttgctcatg ccgtacatat caggcaaaag tgcagctgtc tggagctgaa tctctttcca
    64621 tttttgccag tgttctttat attctttctt gatttgttca atcttatctg ttggatggct
    64681 ctctttgagc tgtttgaatg cgtagattgg tcgatcaaac aactgataat ctgattttcc
    64741 aagttccatt gtttcgcctc tttccgttat cttttgtatt ctacctgaat tttgcgatat
    64801 ggacaaatag aggttgtgaa aaagctgttc tgcatcaagt cataagaaca gccaaacaaa
    64861 aaactgcgat gagcatcacc gcagtttt
//
LOCUS       DADVXE010000009        62301 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.009, whole genome shotgun sequence.
ACCESSION   DADVXE010000009 DADVXE010000000
VERSION     DADVXE010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 62301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.009"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..616
                     /locus_tag="KB913_000592"
     CDS             <1..616
                     /locus_tag="KB913_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBB6818979.1"
                     /translation="FVFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVG
                     KYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGT
                     GVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPF
                     ILALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            613..1386
                     /locus_tag="KB913_000593"
     CDS             613..1386
                     /locus_tag="KB913_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBB6818980.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1383..1781
                     /locus_tag="KB913_000594"
     CDS             1383..1781
                     /locus_tag="KB913_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBB6818981.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1966..2637
                     /locus_tag="KB913_000595"
     CDS             1966..2637
                     /locus_tag="KB913_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818982.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2696..3136
                     /locus_tag="KB913_000596"
     CDS             2696..3136
                     /locus_tag="KB913_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6818983.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3148..3816
                     /locus_tag="KB913_000597"
     CDS             3148..3816
                     /locus_tag="KB913_000597"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBB6818984.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3880..4503
                     /locus_tag="KB913_000598"
     CDS             3880..4503
                     /locus_tag="KB913_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBB6818985.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4559..4945
                     /locus_tag="KB913_000599"
     CDS             4559..4945
                     /locus_tag="KB913_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBB6818986.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5158..6549
                     /locus_tag="KB913_000600"
     CDS             5158..6549
                     /locus_tag="KB913_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBB6818987.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            7160..7528
                     /locus_tag="KB913_000601"
     CDS             7160..7528
                     /locus_tag="KB913_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBB6818988.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            7708..8649
                     /locus_tag="KB913_000602"
     CDS             7708..8649
                     /locus_tag="KB913_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBB6818989.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            8718..9449
                     /locus_tag="KB913_000603"
     CDS             8718..9449
                     /locus_tag="KB913_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBB6818990.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            9593..11773
                     /locus_tag="KB913_000604"
     CDS             9593..11773
                     /locus_tag="KB913_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBB6818991.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            11793..12275
                     /locus_tag="KB913_000605"
     CDS             11793..12275
                     /locus_tag="KB913_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBB6818992.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            12291..13052
                     /locus_tag="KB913_000606"
     CDS             12291..13052
                     /locus_tag="KB913_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBB6818993.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            13183..14517
                     /locus_tag="KB913_000607"
     CDS             13183..14517
                     /locus_tag="KB913_000607"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBB6818994.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            14824..15309
                     /locus_tag="KB913_000608"
     CDS             14824..15309
                     /locus_tag="KB913_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBB6818995.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            15302..15985
                     /locus_tag="KB913_000609"
     CDS             15302..15985
                     /locus_tag="KB913_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBB6818996.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            16111..18756
                     /gene="polA"
                     /locus_tag="KB913_000610"
     CDS             16111..18756
                     /gene="polA"
                     /locus_tag="KB913_000610"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBB6818997.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            18801..19637
                     /gene="mutM"
                     /locus_tag="KB913_000611"
     CDS             18801..19637
                     /gene="mutM"
                     /locus_tag="KB913_000611"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBB6818998.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            19601..20230
                     /locus_tag="KB913_000612"
     CDS             19601..20230
                     /locus_tag="KB913_000612"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBB6818999.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            20282..20614
                     /locus_tag="KB913_000613"
     CDS             20282..20614
                     /locus_tag="KB913_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBB6819000.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            20926..21417
                     /gene="nrdR"
                     /locus_tag="KB913_000614"
     CDS             20926..21417
                     /gene="nrdR"
                     /locus_tag="KB913_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBB6819001.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            21440..22813
                     /locus_tag="KB913_000615"
     CDS             21440..22813
                     /locus_tag="KB913_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBB6819002.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            22813..23739
                     /gene="dnaI"
                     /locus_tag="KB913_000616"
     CDS             22813..23739
                     /gene="dnaI"
                     /locus_tag="KB913_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBB6819003.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            23868..24308
                     /locus_tag="KB913_000617"
     CDS             23868..24308
                     /locus_tag="KB913_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBB6819004.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            24452..25153
                     /locus_tag="KB913_000618"
     CDS             24452..25153
                     /locus_tag="KB913_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBB6819005.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            25150..26271
                     /locus_tag="KB913_000619"
     CDS             25150..26271
                     /locus_tag="KB913_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBB6819006.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            26286..27518
                     /gene="pepT"
                     /locus_tag="KB913_000620"
     CDS             26286..27518
                     /gene="pepT"
                     /locus_tag="KB913_000620"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBB6819007.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            27650..28558
                     /locus_tag="KB913_000621"
     CDS             27650..28558
                     /locus_tag="KB913_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBB6819008.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            28593..28865
                     /locus_tag="KB913_000622"
     CDS             28593..28865
                     /locus_tag="KB913_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBB6819009.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            28876..29922
                     /locus_tag="KB913_000623"
     CDS             28876..29922
                     /locus_tag="KB913_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBB6819010.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            30173..32782
                     /gene="clpB"
                     /locus_tag="KB913_000624"
     CDS             30173..32782
                     /gene="clpB"
                     /locus_tag="KB913_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBB6819011.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(32933..33619)
                     /locus_tag="KB913_000625"
     CDS             complement(32933..33619)
                     /locus_tag="KB913_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819012.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(33597..34091)
                     /locus_tag="KB913_000626"
     CDS             complement(33597..34091)
                     /locus_tag="KB913_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBB6819013.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(34111..35331)
                     /locus_tag="KB913_000627"
     CDS             complement(34111..35331)
                     /locus_tag="KB913_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6819014.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            35478..37313
                     /gene="lepA"
                     /locus_tag="KB913_000628"
     CDS             35478..37313
                     /gene="lepA"
                     /locus_tag="KB913_000628"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBB6819015.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            37509..38420
                     /locus_tag="KB913_000629"
     CDS             37509..38420
                     /locus_tag="KB913_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6819016.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            39416..39667
                     /locus_tag="KB913_000630"
     CDS             39416..39667
                     /locus_tag="KB913_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819017.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            39750..40022
                     /locus_tag="KB913_000631"
     CDS             39750..40022
                     /locus_tag="KB913_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819018.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            40112..40351
                     /locus_tag="KB913_000632"
     CDS             40112..40351
                     /locus_tag="KB913_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819019.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            40498..44781
                     /locus_tag="KB913_000633"
     CDS             40498..44781
                     /locus_tag="KB913_000633"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HBB6819020.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            44880..45245
                     /locus_tag="KB913_000634"
     CDS             44880..45245
                     /locus_tag="KB913_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819021.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            45247..45699
                     /locus_tag="KB913_000635"
     CDS             45247..45699
                     /locus_tag="KB913_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819022.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            46313..47623
                     /locus_tag="KB913_000636"
     CDS             46313..47623
                     /locus_tag="KB913_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBB6819023.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            47646..47957
                     /locus_tag="KB913_000637"
     CDS             47646..47957
                     /locus_tag="KB913_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819024.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            48317..49573
                     /locus_tag="KB913_000638"
     CDS             48317..49573
                     /locus_tag="KB913_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBB6819025.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            49570..50115
                     /locus_tag="KB913_000639"
     CDS             49570..50115
                     /locus_tag="KB913_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819026.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            50116..50616
                     /locus_tag="KB913_000640"
     CDS             50116..50616
                     /locus_tag="KB913_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819027.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            50697..51253
                     /locus_tag="KB913_000641"
                     /pseudo
     CDS             50697..51253
                     /locus_tag="KB913_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            51273..51617
                     /locus_tag="KB913_000642"
     CDS             51273..51617
                     /locus_tag="KB913_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819028.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            51636..52547
                     /locus_tag="KB913_000643"
     CDS             51636..52547
                     /locus_tag="KB913_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6819029.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            52626..53618
                     /locus_tag="KB913_000644"
     CDS             52626..53618
                     /locus_tag="KB913_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6819030.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            53615..53833
                     /locus_tag="KB913_000645"
     CDS             53615..53833
                     /locus_tag="KB913_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819031.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            53846..54256
                     /locus_tag="KB913_000646"
     CDS             53846..54256
                     /locus_tag="KB913_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819032.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            54308..56836
                     /locus_tag="KB913_000647"
     CDS             54308..56836
                     /locus_tag="KB913_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6819033.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            56852..59062
                     /locus_tag="KB913_000648"
     CDS             56852..59062
                     /locus_tag="KB913_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819034.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            59070..60161
                     /locus_tag="KB913_000649"
     CDS             59070..60161
                     /locus_tag="KB913_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBB6819035.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            60182..60724
                     /locus_tag="KB913_000650"
     CDS             60182..60724
                     /locus_tag="KB913_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819036.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VGQEAQKIDAIKIYYVRSAY"
     gene            60919..61176
                     /locus_tag="KB913_000651"
     CDS             60919..61176
                     /locus_tag="KB913_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819037.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            61190..61522
                     /locus_tag="KB913_000652"
     CDS             61190..61522
                     /locus_tag="KB913_000652"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819038.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            61567..62115
                     /locus_tag="KB913_000653"
     CDS             61567..62115
                     /locus_tag="KB913_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBB6819039.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            62122..>62301
                     /locus_tag="KB913_000654"
     CDS             62122..>62301
                     /locus_tag="KB913_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819040.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFL"
BASE COUNT        21017 a        10144 c        13455 g        17685 t
ORIGIN      
        1 gtttgttttt gcaccgttag aaggagaaga cctcgcttca tttctggttg gtgcggcaat
       61 catgatgatc ggaatgacgc tctttttgtt tggagcagat tattctatga tggaagtcgg
      121 agatctagta gggaaatata tgatcaaaaa gaaaagtttg accgttttgg tcagtttggg
      181 atttgctatc gggatcgtga tcacgattgc tgaaccttcc gtgcaagttt tgggacaaca
      241 agtatatgat atatctgacg gagagattgg cagagtgttg ctgattggga tcgtcagcgt
      301 cggcactgga gtatttctag cctttgcgct gcttcgggtc gtattcaagc tatcctatta
      361 tcaattgatg gctataggct acataggcgt tttgatcgcc tcatttttca ccagttccga
      421 atttatgccg attgcttttg attcgggggg agtgactact ggtccagtaa ctgttccatt
      481 tatcttggcc cttgccggag ggatgactag tatgatcaaa caaaagaaaa atgaaaatga
      541 cagttttgga atggtcggta ttgcttcgtt agggccgatt cttgccgtga tgattttggg
      601 ggtgatcttc caatgagttt ctggcagcaa gtgatagatg gaatcgaaat cgttaccatg
      661 gaagtcattt tggcagtggc acctatcgta atcctatttg ttttaatgaa tatcattagt
      721 tttcgtatgc gcaaaaagcg tttctttgac attatgaaag gtttcttgat aacgactatt
      781 gggttgatcc ttttcctgca cggagtcaat atggcttatg taccggtagg acagcattta
      841 ggcagtgcta ttgcgggatt gccttacaat tatatactgg ttccccttgg ctttttaatg
      901 gggttcttag tagggtttgc tgagccggcg attcatgtaa tgatcaaaca ggttgaagaa
      961 ttgagcgagg ggagaatccg atcgaaaatc atgctgatgg taatttcaat tgggatcggc
     1021 gcagcagtag gattgtctat gtggcgtttg ctcgtcggat tctctcttta ttatttcttg
     1081 atcccaggat acgggctagc atttatttta ggacgaaaag tggacaagat ctttttagca
     1141 atggcttttg ataacggtgg agtagcaacg ggcccgatgt gttcgacatt tattttatca
     1201 atgagcgtgg caatcgctgc acaaattgaa ggaagagatc cgatcattga cgggtttggt
     1261 gtggttgcaa tgattgcatt gacaccaata ttatccactt tagtactagg atatatttat
     1321 aaacgaaaag atgaaaaaga cagaatcgaa aaagaaagat tgcaaaaatt gggggaaagc
     1381 aaatgaaaga tcttgtagca ttgaatcttc acatgattgt gacgatcgtt gacggaggaa
     1441 tgggcgaaga tgttatcgac ttttcaaaag aagcaggtgc agcaggcgga acgatcttac
     1501 atggaagagg ttctggtgta catgattcag ggaaattttt aggtttggac atttcgccag
     1561 aaaaagatat tgtgttgaca ttagtacccg atagtttgac gaataaagta atggatgcga
     1621 ttggtcaagg catcaacatc gatattccag gtaatggtat ttgttttagt attgatgtag
     1681 acaaagtcat tggtatcact aagattcatc aatatcgaga aattatcgga atgcaagaac
     1741 ttttagatga aaataacgat agagaaaagt ctgaatcata gacaagcgtt tgaagaggaa
     1801 ataaacacaa acaagaaggc ggatgagcgt tatttccgct tttttgtttg tatttttctc
     1861 gtgaatactt atgaaatagt aaatttttat gaaattctac tctaagcatc agactttctt
     1921 ttcaaaatat gctattttaa aaatgatgaa aaaaggggga gaaaaatgaa ttttttagtt
     1981 gttttaaaag atactctgat tgagcgattt acatttctat atgttcaatt gcaggaaaat
     2041 aaaacattgc tgcatttttc accagagttc catctagagg ggctaacatt aggagaaatc
     2101 tatcaagcag aagggctgtc ggctgttttg cactttttta aggtagaatt ggaattacca
     2161 gtaaaagatt atatcgagct ttctcttgaa tcttgggatc gagcagtggt tgaactgttt
     2221 ccagaaggtt taatgatcga tacaaacgat gggaagatcc atctgactgc agcagaactg
     2281 caaaaacaaa tgcgttatca aatagatgac gaaaattctt tttctatttt tagacgtcag
     2341 caaaagattc taaaaagctt tttaaaagtg atcagtaaaa aacggaatct gatcaaaacg
     2401 acacagctgt tgaaaaaata tccaggtctg cttcacacgt ctattcaatt tcctcaattg
     2461 attacgatga tccatcgttt tatacgtatg caacagctac catctaagaa gctgtttctt
     2521 ccattgacgg acacatttcg agtagtcaac agagaagata aaaagaaagt gattgtgatt
     2581 gactttacca gaaatcggaa tgtccttcac caagttgcaa tggaaaaggc caattaaggc
     2641 tttttctttt tggatttttt tgtcataata aatattagat gatggaggag ataatatgat
     2701 gcaaacatgg ttagaaaggc taatacgatt tcagcagaac tatcacaaac ttatgcaggg
     2761 aagatatgcg aaatttgatc agttgaatcg cggtctattg atcgctgcgc ttgtctttag
     2821 tttgctaagt cgttggttgc cctatagaat cggacaattg ttgttcatcg tctttttcgg
     2881 atggatgata tttcgtttcc tatcaaaaaa aatctacccc agactaaatg agaatcaacg
     2941 ttatttgaaa tatcttgata gagtcaaaga aaaatatcat cagataaaaa acaaaaagca
     3001 agtcaaaatg gatcgaaaaa gttatacttt ttttgagtgc ccgaattgtc atcaaaagca
     3061 gcgtgcacct aaaggaaaag gacgaatacg tgtgacatgc aaaacatgtg gtataaaatt
     3121 cgaaacgaat gtttaaggga gaaaagaatg aaattagtat tattacgtca tggcgaaagc
     3181 gaagcaaatt ttgaaaatta ctggacagga tggctagatg tcgccttaac agaaaaagga
     3241 aaagaacaag cagcagttgc cggtcaaaaa atgcttgaag ccggacttca attcgatgcc
     3301 gtttatacct ctgttttgaa acgtgcgatt cttaccggac aagtcgcact agaagaaatg
     3361 ggtcagttat ggcttcctat aataaaaaca tggcgtctaa atgaacggca ttatggggat
     3421 cttgtgggta aaaacaaaga taagatgaaa gaaatatacg gaaaagatca agtaaaaaca
     3481 tggcgcagag gatatacgga agttccgccg ttaaccgcag aaaatagatt tgaccgcaga
     3541 tatgatcact tggatccgca tttgatccca tacggagaaa gtctggaaat gacagtgaat
     3601 cggatcattc ccttatggca agatcatcta gcaccaaaac taaaagatcg gcaagattta
     3661 ctagttgtgg gtcatggtaa tagcatccga gcactgacaa aatatttaga agatgttcct
     3721 gaagatcaaa tggatacgat cgatatccca aatgcacaac caatccagta tacattagca
     3781 gatgatttga caattctgga caaaaaaata ctttaaagaa cacctttatc taaaagtgag
     3841 agatagaaaa aagaagcaaa ggaatggaac aaaaggaaca tgaaaaatta tatatgggac
     3901 tttgatggta cattgtttga tacgtatccc gcaatggtag atggtgcatg gcaagcacta
     3961 aaagattttg gtatcagtat ggacaaaaaa gaaatctact tcaaaatgaa aaagtattct
     4021 actagttatt tgatcaatga atcaaacttg aatgccagag agtttaatga attatttcac
     4081 cgatatgaaa aagaaagtac ggaagtttcc cgtccatttc cagaaacgaa acaagtactg
     4141 gaaatgctaa aagacaacgg cggtcgtcat ttcatcctga cccaccgttt gacagaatca
     4201 acatggggcc tgttaaaaga acatcgattg gcacatctga ttgaggaagt agtagggatc
     4261 gatcaggact ttcctcgtaa acctgatcca gcatctttaa attatttgat cgatactttt
     4321 catttagaaa gaacagacac gatgatgatc ggcgatcgtc gtttagatat cgaagcaggg
     4381 aaaaatgcag gagtcgctac ttgtctttac gacatcgatc attttctggg tgagatcccg
     4441 gcagattatg tggtaggaaa tctgaatgaa atccttacct tgcagagcat cattaaaaag
     4501 tagtatcccc tttcaaagga gatatgttat aattttcata aaggagtgat aaaattatat
     4561 ggaaatcaga agacaaaaag aagttgtaga agcatttcat tatgatatga gattgccgaa
     4621 ccaagaagta gaaacagatt tgaaagtagg cttctcgcct ttaaaagaaa cgatcgaaaa
     4681 ctatccgaaa gaacatagca tcgtaggagc acgcttagag ttccgtttag tgtttgatac
     4741 atatgtttta tctggaagtg tgagtcagat caatcatatc ctcaatcgga aaattgaagg
     4801 tcaaaatgat gtcacacaag aagaagtgga cgagctagta gcaccgttat tcgatatcgt
     4861 acgccgaatg tcttatgagg tgacagagat cgccttagat cagcctgggg taaaattgaa
     4921 ttttcaatca gaaaaacaag aatagacagt aaaaacatac ctgcgataga ttaaagctat
     4981 cacaggtatg tttttttatt actaattgta agcaaaaaga atgtcatttc gataaaaatc
     5041 gtctaaaata taaaagtcac tgaaaaaaat tttttcagga ggatggttga agaatcattc
     5101 tcgggaacct ttacttcctt cgatggactt gtcattaata atatgaggag gagaaaaatg
     5161 acaacactca tcacagtttt agtggttcta gtttttgcgg cattattata tgtgttctat
     5221 cgtatgcaaa agcgccatac aaaattttca acacgcgtct ttacagcatt aggagttggt
     5281 atcgtctttg gcggtctgct tcaattgatc tttggtgtag acgacaaagt cgttactcaa
     5341 tcaatggaat ggatcgggat tgtaggtcaa ggatatgtat cattcttgca aatgctagtt
     5401 atgcctttag tgtttatttc gatcattggt gcattcacaa aaatgaaagt ttctgaaaag
     5461 ctagggaaaa ttagtgcgac tgtattgact tctttacttg gaacaacagc tattgcagca
     5521 ttgatcggaa ttggttcaac aatgctgttc ggactccaag gagctaaatt cacacaagga
     5581 gctgcagaaa cagcacgaat ctctgaactg gcaacacgtc aggaaacagt tgaaaactta
     5641 tcgattccac agcagatttt atcctttatc cctaaaaacg tttttgctga tttagcaggt
     5701 agtcgtgcaa caagtacgat tggagtcgtt attttcgcgg catttgtcgg aatcgcttat
     5761 ctaggcgtga aaagaaaagc gccaaaagaa gcagcattct tttcagattt agtcgacagt
     5821 ctgtataaaa tcattatgcg gatcgtgacg cttgttttgc gtttgacacc ttatggagta
     5881 tttgctttga tgacaaacgt tttggcaaca agtgattttg cagctatcgt caatttaggt
     5941 aaatttgtcg ttgcttctta cgtagcattg cttgctgttt tgattgtcca ctcactgatt
     6001 ttgattggtg caaaagtcaa tccaatcaac tatttcaaaa aagcctttcc ggtattgagc
     6061 tttgcgttta cttcacgttc aagtgctgga gctttgccat tgaatatcga gactcagaca
     6121 aaagctttag gagtagatga tgcaacagct aatttctcag caagttttgg tttgtctatt
     6181 ggacaaaacg gctgtgctgg cgtttatcca gctatgttgg caacgatcgt cgcaccagca
     6241 gctggagtga atgtctttag tttggaattt attttgatgc ttgtggcaat tgtaacaatc
     6301 agttcttttg gtgtagctgg agtcggtggg ggcgcaacat ttgcttcact gatcgtttta
     6361 ggggcaatga acttgccagt agcaatcgtt gggttagtta tctctgttga accattaatc
     6421 gatatggcac gtacagcagt aaacgtcagc ggtagcatgg tagctggtat cgtgacaagt
     6481 gcacgcatca aagatttaga tcgcgatgtc atcaatgatg attctaaagt gatcgatgtg
     6541 aatgcatagt caaaaagagg ttgtgataga agtggtcagc tttaagaaat aagaagaagt
     6601 ttcctaaaaa tagtttctca aatttttgtg aaatttcggc ttatttccga gaagctactt
     6661 ctgaaacacc gtgaataaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
     6721 ccaaacaaaa atagttcctc atattttacg tttggttgag cttattaccg cagatgcaag
     6781 cttttgaaca ccgtttaaga aagaggtcgt gagcctgccg tttcactctg agtcacaaag
     6841 agcaatttca aaaaatagct tctcatgttt gttgaatatt gtgtcttgtg accgaggagt
     6901 tgtcaggaga acaccgttta ccagaggttg tgacttgttt ttagtcacga cctctttttt
     6961 tatttattcc atataaatac acattattta ttccgaaaag tgaaagcgca aataacaaaa
     7021 acaaccaact tatttattat taaagaaaag cgtatttaag taggacgatt ctgttgagag
     7081 ctttcgtaga ttttcccatt ttcctatggt aaactgacaa agttgagaat gttagaacag
     7141 atcgtttagg aggaaacaga tgtttacgaa tgaaataaaa atcatgcttt atgtggacga
     7201 tgtagaaaaa aatgcaacgt tttggagagc agttggcttt gcggaaaaag atcgtcaaga
     7261 aatggatggg acgcttataa ttgaagtagg agttgaggac agtcaaacct catttctgtt
     7321 atatgatcga gcatttgttg agtcccattc acctggcaca gctactagtg ccccatcttt
     7381 gatgttttac agtaaagata tctttggact atataaaaaa atgcagacgc aatcagtcac
     7441 attaggtgat atggtacagc ttggagaaga atatgtcttt aactttgctg atcccgatgg
     7501 caactacttt gcggttacag gtaaataata gaaataaaga ctttgttttt ctgtgcgaaa
     7561 caggaaagcg aagtcttttt aattcaaata ataatattat gtaaacaaaa aactttccat
     7621 gcgtaattat acacaagcaa ataaatcgtc aaatgcgaac gccttcttta tactgtttag
     7681 gaacgaaaag aaggaaggaa gaaatacatg gattatcaag tactgcttta ttacaattat
     7741 acaaaaatcg aagaaccaga ggaatttgcc aaaaatcatt tagccttttg caaatctttg
     7801 gatcttaaag gtcgtattct agtagctgaa gaaggaataa atggtactgt gtctggaacc
     7861 gttgaaaaca cgactgccta tatgaaagca atgaaagctg atcctcgatt tgctgatacg
     7921 atgttcaaga tcgatccaag cgaaggacat gcctttaaga agatgtttgt aagataccgt
     7981 ccagagcttg taagtttaaa gctagaagag gacattgatc caaaccaagt gacaggtgcc
     8041 tatctttcac cgcaagaatt taaagaagct attttagatg aacagacagt ggtgattgat
     8101 gcacggaatg attatgaata tgacttggga cattttcgag gggctgtacg cccagatata
     8161 cgcagttttc gagagcttcc agactggatc cgcgagcaca aagaagaatt tatggaaaaa
     8221 cgggtagtga cctactgtac tggtggcatt cgttgcgaga agttttctgg ttggcttgtc
     8281 cgtgaaggat tcaaagatgt cggacagctg catggcggta ttgctactta tggtaaggat
     8341 cctgaagtcc aaggagaatt atgggacggc aagatgtatg tgtttgatga acggatcgct
     8401 gtcgatatca accaagtaga taaacaaatc gtcggtcgcg actggtttga cggaacacca
     8461 tgtgaacgat atatcaattg tagcaatcct gagtgcaatc gtcagattct tgcttccatt
     8521 gaaaatgaag aaaaacattt aggagcatgt agcatagagt gtgcgaaaca tccgcgcaat
     8581 cgctatgttc aagaccatgg aatctctcca gaagaagcag aactgcggtt tacagcttta
     8641 attaaataga aaacaatagt tttgattgtc gaccatttcc aatatgcgct atactagcgt
     8701 tgaggatggt gatccacatg aaatcattga tttatgctat tggggatgtc catggcaaac
     8761 atgagctttt tgaaaaactt attcactatt atgatccaaa gatccatcag cttgttttat
     8821 taggggatct caatgatcga ggtcctcgta caaaagaatg ttttttatta ggaaagcaat
     8881 tagtcgaaga aacaggagcc atttacctcc ggggaaacca tgaagaatat tttttgcaat
     8941 ttctgcaatc accggaggac tggtatgcgc cttatatgag aaatggtgga aaagaaacgt
     9001 ttgaaagcct gattcaccca ggggcatcgg aggaatactc cccaactgaa atctcgatga
     9061 tgatccaatc gagatattca gaactgatta aatttttagt ccagcgcccc ttgtattatg
     9121 aatgggaaaa ttatcttttt gtccatgccg gtgtggattt gacaaagaaa gactggcgta
     9181 agacaagtct aagagacttt atttggataa gggaaccatt tcatgaaggg aaaaacaata
     9241 caggtaagac aattgtattt ggacatacga ttacaccaat gctccatgga gatatgcaga
     9301 caacagacct ctggattcag gatcataaaa tcggaatgga cggtggggct gtattcggag
     9361 ggtcattgca tggggttgtt tttgacaagg aaggtattct tcaagatatt gaatatcaga
     9421 acaacgaagg accttggcat ggaatctgac taatggaaag aatgaaggag ctgtgacttt
     9481 gttgcggctc tttttatttt tatagagaat attgtttctt tcagtagttt aacccaggat
     9541 aaaaagtatg atagaataaa gaagcaattt ttagcagaaa agaggcattt taatgacgga
     9601 aaatttgaac cagacgatca ttcagcttgt acaaaaagaa ctttcagact atcgtcctaa
     9661 gcagttgact actgtactta atttgttaaa tgaaggaaac actgttcctt ttatcgcgcg
     9721 ttaccgaaaa gaaatgactg gaagtcttga tgaagtccag attcgtgaaa tcgaagagcg
     9781 gtatgcctat cttgaaaact tagaaaaacg taaaactgaa gtgattcggc taatcgatga
     9841 acaagggaaa ctgactcccg agttagaagc agaaatcacc caagccgtga aaatgcaaca
     9901 agtggaagat ttgtatcgtc catacaaaca aaaacgacgg acaaaagcaa cgattgctaa
     9961 agaaaaagga cttgaaccac tcgcgaagtg gctgatgcag cttacagatg gagaggtgca
    10021 atctgaagca gaaaaatata ttgacaaaga aaaagaagtc tcttctgccg aagaagcgtt
    10081 gcacggtgct catgagatta ttgctgaaca agtcagcgat aatgcaaaat ttcggacttg
    10141 gattcggtct tatacgtata acaaaggtat gtatgtcagc aatgtcaagg atgagcaagc
    10201 agatgaaaaa ggcgtatatg aaatgtatta tgactttgca gaacccgtcc ataaaatggt
    10261 ttctcatcga atattagcta ctaatcgtgg agaaaaagaa gatattctga aagtattctt
    10321 tcaagtagat gaagcagcaa ttttagctta cttggatcgc caaatagtca aaaatcctgc
    10381 ctctccttct tcttcattcg tcagagaagc ctatcaggat agttataaac gctttattca
    10441 gccagcaatc gagcgagaac tgcgcaatga attgactgaa aaggcagatg agcaagcaat
    10501 cgctattttc ggcgaaaacc tccgtaatct tttgttgcaa ccgccactaa aaggtaaagt
    10561 tgtcctggga tttgatccgg cttatcgtac tggatgtaaa ctagcagtcg tagatgcgac
    10621 agggaaagtt ttagcaatcg aagttattta tcctcataaa cctgcagcgc aagcaaaaag
    10681 agaagctgct ggaccagctt ttatccaatt aattaataaa tatcaagtag atatggtagc
    10741 tatcggaaat ggtacagcca gtcgggaatc tgaacttttt gtggctgagc agttgaaatc
    10801 cgccgaccat aaaacctatt acgctatcgt caacgaagca ggcgcttctg tttactccgc
    10861 tagcgaaatt gcacgaaaag aatttccgca tctacaagtt gaagaaagaa gtgctgtttc
    10921 tattgcccgt cgcctgcaag atcctttagc tgaattagtc aaaatcgatc ctaaagctgt
    10981 cggagtaggc cagtaccaac atgacgtttc tcaaaaacgt ttggctgaac aattggattt
    11041 tgttgtggaa acagcggtta accaagtagg tgtggatgtg aatacagcaa gcccgcagct
    11101 cttgcagcat atatcaggat tgaataaaac aactgcccaa aacattgtca tttatcgtga
    11161 agaaaacgga gaattcaccg cacgaactca attgaaaaaa gtgccacgct taggaccaaa
    11221 agcatatgaa caagcaatcg gattcttgcg agtccctggt gggaaaaaca ttttggacaa
    11281 cacaggtatc catcccgaaa gttattctat tgcaaaagaa atattaactt cagtccaact
    11341 ttcagaaaaa gagcttggta cagaagaagc agtagaaaaa ttgacacgat tatccgtaga
    11401 gaaactggct gaaagcctat cagtcggaga agaaacgtta gccgatattt tagctgggct
    11461 gacacaacct ggacgagata tgcgtgatga gatgccagcg cccttattac gtacagatgt
    11521 attgagtatg gaagacttga aaccagggat ggaattgact ggaacggtcc gtaatgtcat
    11581 tgacttcggc gcatttgttg atatcggtgt gaagcaagac ggacttgtcc atatatcgaa
    11641 actcagcaaa aaattcgtca agcatcctac agatgtcgtg tcagtaggag atatcgtaac
    11701 agtttggata gaacaagtcg atacgaaaaa aggcagaatc agtttgacga tgctttcccc
    11761 ttatgaagag taacaatgag gagtaacaaa aattgacaca agaagaactg cagcagttag
    11821 tagaagagat atcattaaaa agcttccagc ttcctttcaa gcaccaagca atgttcaatc
    11881 cacgcttacg tacaactggc gggcgctatc atttaaacga tcatcattta gattttaatg
    11941 cgaagctatt tgaagagtca gacgaagaga cgattgcagg aatcatcaaa catgaacttt
    12001 gccattatca tcttcatcta gctggaagag ggtatcagca taaagatatg gatttcaagt
    12061 atcttttgaa aaaaacagga gggttgcgct atgcaccagc cttgacgaag aaacagataa
    12121 agatggagta ttatcgatgc caagattgtt ctgccacgat ctgccgcaag agaagaatcg
    12181 atgtacgcaa atatcgttgt ggaagatgtc atggagaaat caaatggatt gagacaaaaa
    12241 gagaagactt taatgaagca caaaaaatca gatgaaagga tagaaggcct ttggaaaaaa
    12301 gtgagcagag gaatctaaaa gactggaatc agctattaaa ttttttagcc gcacctgaag
    12361 agggaaattt tgaggaactg acggcaccta cacttatttt agctggaaac tgtcttccta
    12421 tcttagctga taaagcagca caaatgtatt taaatggcca agtagatcaa ttgtttttgg
    12481 tcggaggggt ggggcatgcg actagaatcc tttatgagaa ttttgaaaag caaggatttc
    12541 attttgaaga tggcatgagt gaaagtgaaa tctgtcgtca gtatctaaaa gaagtctatg
    12601 atttgcccga taaggctttt ctgatagaat cgaagtctac aaattctgga gagaacgcca
    12661 ctttttcact ggagattctt cattccttag gagctgtacc agaaaaaatc ttattgatga
    12721 atgatccgac actgcaacgc aggactcgag caacttttga gaaagtatgg caaaatgaac
    12781 aaactatttt cgcgaatgct gtgccatttg tgccggaaat ccttcacttt tctgaagaga
    12841 tcatctttac agcaaaagaa ctgaatcatc aatggcctaa ggaatatttc catgcgctag
    12901 tattaggaga aatggaacgt ctccatgacg atgagaacgg ctatggtccg aaaggaaaag
    12961 attttattcc tcacattgat atatcagagg aagtttggtc ttcttacacc agaattaaag
    13021 agtcaataaa aacggatttt tctcgtactt gaccatttta gcaagcgaat cctcctttcc
    13081 aaataaattt ggttgaaatt ttcaatcgtt tataagataa tgaggagcgt gttgaatgta
    13141 atagctaaaa gaatggacgc tagataagag aagaggattc aaatggaaaa tcaaaataaa
    13201 ttgtatcatt ttgttggtat caaaggttca ggaatgagct ccttggctct tgttttacat
    13261 gaacaaggtc taaatgtcca aggatcagac attgaaaaat atttctttac acaaagagat
    13321 ttagaaaaag caaatatcac gattctgcca tttaacgcag ataatgtaaa accagggatg
    13381 acgatcattg caggaaatgc atttcctgat tcacatgaag aaatccagcg agcaaaagaa
    13441 ttaggtttgg aagtgattcg ctatcacgac tttattggtc attttatcca aaattatacg
    13501 agtatcgctg taacaggctc tcacggaaaa acaagtacga ctggactgct ctctcatgta
    13561 ttgagtggtg tccgtccaac aagttatcta attggagatg gaacaggaca tggtgatccg
    13621 caagcggaat tcttttcatt tgaggcctgt gaatatcgcc gtcatttcct tgcctattca
    13681 ccagactatg caatcatgac caatatcgat tttgatcatc cggattatta tacaagtatc
    13741 gacgatgtat ttacagcttt ccaaacaatg gctggacaag tgaaaaaagc tatttttgcg
    13801 tatggtgacg atgcttattt acgcaaatta aaagcaaatg tgccgattta ttattatggt
    13861 gtcacagaaa acgatgatat ccaagcacga aacatcgaac gcacaacttc tggttctgct
    13921 tttgatgtct atcatgggga tgaatttgtt gggcacttca ctgtaccagc attcggtaaa
    13981 cacaatatct taaatgcttt aggtgttatt gcagtagctt atttcgaaaa actggatctg
    14041 aaagaagttg cagaagaaat gctgactttc ccaggagtaa aacgtcgatt cagtgaaaag
    14101 atcgtagcag acatgaccgt agtcgatgat tatgcgcatc accctgcaga gatcaaagca
    14161 acgattgatg gcgcacgcca aaaatatcca gataaagaaa taattgcagt tttccaaccc
    14221 catacgttta cgcgtacgat tgcattgatg gatgaatttg cagaagcact tgatttagct
    14281 gataaagttt acttatgcga tatttttggt tcggctcggg aagaacaagg aaacgttaag
    14341 attgaagacc ttggagcgaa aatcaaaaaa ggtggagaag tcatcaaaga aaataatgta
    14401 tctccattgt tagattatca tgatgcagta gtaatcttca tgggtgctgg agatgttcaa
    14461 aaatttgaac aagcgtatga aaaactttta agcagcacga cgaaaaatgt actgtaatac
    14521 aattactgca gtgtccttat aaaaatagaa agagggggag tggcaaaaat cttgccaagc
    14581 cccctttttt gcaacttatg ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc
    14641 caatcaaatc aaaaacatga gaagctgttt tttcttggct gttcttatta tttgatgcag
    14701 gacagctttt tcacgacctc tgtaaactat aggaatctgt taaatcaagg gagcagaact
    14761 tgccttttac gctacttttg gtacaataat gtatgattaa aaataaactg gagggtttct
    14821 atcttgaaca taggtaagcc gagaaaacta ggaaaaacaa taaatgaaat cgaggaaggc
    14881 gactcgttat ccttaacaga atctattgaa gataaccagc ttttgctgta tttgggattg
    14941 acgaatgatg caaatccttt gtatatccaa catgactttg cacaaaaaac agaatatcaa
    15001 cagccaatcg ttccatcagt gatgctgatg gggatcatca caagtgcaat ttcaaagcat
    15061 cttcctggac caggatcaca tgttgtcaat ttttctgtca attttattga accggttttc
    15121 cattatgaaa cactgacttt tcagtttgag gtcataaaag tagataagat gaaggatgtg
    15181 gtgacgattt ctgtagaagc ggagaatacg aacgaagatc gtgtgttgga tgctgtcgtt
    15241 atggtccaac cgccacaagt tcctgaattg gaaatagcaa tcgaaagtga aggtgaattg
    15301 aatgaataat ccaagtacat caatgtcagg tatcaatcgt ttttatgcaa aagtttatgg
    15361 atttttaggt atgggacttg cccttagtgc agtcacttct tacttggctc tttgggtatt
    15421 tcctttgcaa ttagcaactt ttatcaataa ttttccacta ggctttgtgg gtctgtggat
    15481 cgttgaactg attttagtaa tggttctagg cgtaaaagca caaaagaatc cgagcttagc
    15541 aatcggtgga tttattgcct actctctttt gaatggcata acattagcgg ttactcttgc
    15601 atactacgat attggaacag taacgcaagc tttcttgaca gctactttga tgttcatggg
    15661 gatgtctgtt gtcggagtaa caacaaaaag agatcttagc ggggttggaa gagcaggaca
    15721 ggcagcttta atcggagtga tcattgcact agtcttgaac atcttcattt tgagaagtag
    15781 cgtagttgag ctgttcatct ccctactgtt agtcgtcatc tttgcaggga ttacagctta
    15841 tgataaccaa agcatccgta atatctatgt ccagacaaac ggaacagcac atagtggaat
    15901 tgctgtattc atggcattga agctgtattt ggactttatc aacttgttct tggcgtttct
    15961 gagaatcttt ggacggaaca actaaaaaag aaaaaaattc atcagttggg gctataccga
    16021 attatttggt atggtcccgc tttttctttt cgcattccgc aggattcttt gttagaatga
    16081 ataagaactt tacagtaagg agttaagaag atgacaaaaa ataaattatt actcgttgat
    16141 gggaacagtg tggcttttcg cgcattcttt gcgcttcaca attctcttga acgtttcaaa
    16201 aatagaaacg gtcttcatac aaatgcaatc tatgcattca atacgatgtt tgaaaatgtt
    16261 atgcaaaaag agcaaccgac tcatgttctg gttgcgttcg atgcaggaaa aacgactttt
    16321 cggacagaaa tgtatgcgga gtacaaaggt ggaagatcca aaacacctgg cgaattcaaa
    16381 gaacaaatgc catatatacg tgatttgttg acaggactag gggtacagta ttacgaattg
    16441 cccaattatg aagcagatga tattatcggt actttggcag aaaaagtaga caaagatcaa
    16501 tttgatgtcg tcgtgctttc aggtgatcgg gatttgactc aattagctag taaagaagta
    16561 aaagtggata tcactgtaaa aggtgtcagc gatatcgaaa gctatacacc agaacatgta
    16621 gcggaaaaat atgatgggtt gacgccaaaa cagattattg acatgaaggg actagccgga
    16681 gatgcctctg acaatatccc cggtgtgact aaaatcggtg aaaaaacagc tatcaagcta
    16741 ttgaaacaat atggctcagt cgaaggaatt tatgaacata tcgatgaaat gaagcaaagc
    16801 aaaatgaaag aaaatctgat aaatgacaaa gagcaggctt tcttatcgaa aaaattggcg
    16861 accatcaata cttcagcgcc tgtggatgtc tctatcgact cattgaagta tgaagggaaa
    16921 aatctcgata aactcgttcc gttttataaa gaaatggatt tcaatcagtt cctttctaaa
    16981 ttgaatatcg tagaagaaga agtaaaaatg gatgatattt tgtttgaagt cgttcatgaa
    17041 ttcaaagagg aaatgtttac tacggatatg gcgttgtacg tggaaatgat gggcgacaat
    17101 tatcatacag aggaaatcgt cggagtagcg tgggggacag aaaagaaaat ttatgtcacg
    17161 aacgatctat ctgtattcga aaaccgagcg ttccattctt ggatcactga tccgactcgg
    17221 ctgaaaaaag tatatgatgc gaaacgaact tatgttgctt taaaccgcta tactggaaaa
    17281 acgaaaggaa tcgattttga tgtcttgcta ggtgcatacc ttctcgatac gaatgaaaaa
    17341 agcacagata tcgaaggaat agctgctcat tacggataca acgatatcca atcagatgaa
    17401 gctgtatacg gcaaaggggc gaaaaaaggt ttaccagaag aagaggaact cttttttgct
    17461 catttagcgc gaaaagtagc tgcaatcaat gcgttgacac caaaattgag ccaagaactg
    17521 gcagaaaaaa accaagaaga tcttttccgg aaaatggaac tgccattgtc tatcattttg
    17581 gcagagatgg aaataagcgg gatcaaagta gatgcgactc gcttacaaga aatgaagggc
    17641 gagttctctg ctcgcttaag agagatcgaa caaaaaatct acgaagaagc cggcgaagaa
    17701 ttcaatttga attcaccaaa gcaattagga gtgatcttat ttgaaaaaat gggattaccc
    17761 gttatcaaaa aaacaaaaac tggatattcc acagccgtag atgtactgga acagcttcgt
    17821 gaacaagcac caatcgtaga ggatatcctc acctatcgtc aaattgcaaa aattcaatct
    17881 acctatgtcg agggactgct gaaagtgatc caatcagatg gaaaagtgca tacccgttat
    17941 gtccagacat tgacccaaac aggacgatta agctctgttg atcctaattt gcagaacatc
    18001 ccgattcgat tagatgaagg gagaaagata cgtcaggcat ttgttcctag agaaaaagac
    18061 tggctgattt attcttctga ctattcacaa atcgagttac gcgtacttgc gcatatctca
    18121 aatgatgaac atttgaaagc tgccttccta gaaggtcaag atatccatgc cagcacagcg
    18181 atgcgtgtat ttggaatcga aaaggcagag gatgtcacac caaatatgcg taggcaggca
    18241 aaagcagtga attttggtat cgtgtatggc atctctgatt acggactttc acaaaatcta
    18301 ggaatcagcc gaaaagcagc acagcaatac atcgatacgt actttgaaaa atacccaggt
    18361 gtcaaagaat atatggaaag aatcgtacgc gaagcaaaag accaaggcta cgtcgaaacg
    18421 ctgtatcacc gccgtcgata tctgccagac atcaattcaa gaaattacaa tatccgttct
    18481 tttgcggaac gaacagctat caatacacca atccaaggaa gtgctgctga tattttgaaa
    18541 atcgcgatga tcgaattgga taaacgatta aaagaaacag gtcttcaagc tacgatgctg
    18601 ttacaagttc atgatgaact tgtcttcgag gtaccggaaa aagaacttga atcattagat
    18661 aaattggtga aggaagttat ggaacaagct gtttctcttc atgtaccact gatcactgac
    18721 agcagttggg gaaaaacgtg gtacgaagca aaataaacat tgtttaagac agagcaatat
    18781 aatgaaggtg aaaagaaaaa atgccagaat taccagaagt agaaaccgtt cgtaaaggat
    18841 tggaacggtt agtagtagga aaaacgattc aaaaagttca ggtcttgtgg cccaagatca
    18901 tcgagcaacc agagacaccc atctttgagg cttctcttgt tggcgaaacc atccaatcca
    18961 ttggacgtag agggaagttt ttaatttttc atctcgatca ttgtgaactg atctcacact
    19021 tgcgaatgga aggaaaatat caatttacga aagaaaatac accaatcgat aaacatacgc
    19081 atgtactttt cttttttgag gatggaagcc aacttcgcta caacgatgta cgaaaatttg
    19141 gtcgtatgac aatcgtcgaa aaaggagcaa gtgcaactta ccgaggaatc atgaaattgg
    19201 gacctgagcc tttgccagat agcttcttat tagcagattt cgcaaatgga ctgaaaaagt
    19261 cccacaaagc aatcaagcca ttgctgctag accaacgtct agtgactggt ctaggtaata
    19321 tttatgtaga tgaagcatta tgggaagcga agatccatcc agaacaaccg gcgaacacac
    19381 tgcgccccaa agaggtagaa caattacgtc tatcgatcat tgatgttttg gatcgtgcaa
    19441 tagaagccgg aggtaccacg attcgcagtt atttgaatgc attaggagaa tcaggcggat
    19501 ttcaagtagc actgcatgtc tatcagcaaa ctggcaaacc atgtatacgt tgtggaacgc
    19561 cgatcgtgaa aacaaaagtg gcacaaaggg ggacgcacta ttgtccgaat tgtcaaaggc
    19621 taaaaatcgc aaagtaggat ttgttttagg tttgacgggt ggaatagcta ccggtaaaag
    19681 tacggcagcc aaagtctttc agtctcatgg atttcctttg atcgatggcg atgtgattgc
    19741 cagagaaact gttgagcctg gaacgcttgc tctgaggaaa attgtatcag tgtttggcca
    19801 agaggtattg cagcctgatg ggcaactaga tcgagggaaa cttgggatga ttgtttttcc
    19861 atcaaaggaa aaacggcaaa aacttgatca gctattagat ccgtttatcc gaaaagcgat
    19921 aaaagatcaa atcgcctctc taagttccaa tcatccttta gtaattgtag atatcccatt
    19981 gctctacgaa ggtcattatg accactatat ggatgcagta gctgtcgttt atactacgcc
    20041 agaaactcag cttcagcgtt tgatgaaacg taatcaactg acgctagaac aagcgcagca
    20101 gagaattagt agtcaacttc caatcgaaga aaaaaagcag cgtgcggata ttttgttcga
    20161 caacaatgga acaaaagaaa tacttgtggg acaaatcgaa aattggcttt ttgctaatcg
    20221 ctttctttga gtatctgtgt caattttgct atcctgagta tatagaaagt gagggatagc
    20281 gatgggatca ttaaaaaatc aaaaggataa agtcgtaggt aacgcaaaag aaaaaatcgg
    20341 cgagatgctc aataaagaaa atctaatcga tgaaggtcgt acgcaatcag aaacagcaga
    20401 agaaaaagaa aagcagtacc aagcaagaat cgatgaaata gaagaccagc aggcagaaga
    20461 agaagcgaag cggcaagatt tgactcaaga acgaaaaaat ccgacacctg atcgtagtaa
    20521 aacaccgctc ccagaaagtg accacattcc cgatgagcaa aaaatcgagg aacagcgaat
    20581 gaaacactat acaggaatcg aagagaagtt ataaaatagt aaaaaatcga gatgtgactt
    20641 gaagcagatg agaaggtgtt catctgcttc aagttttttg tgctagatga ctaaatcagc
    20701 ttttgtgtaa gttatttctc agtaatcaag gtgatcagta ttggaaaatt gaaatttagt
    20761 aaggacaggg gacacaatta cgcatgaaag tagaaaaaat tgttcttata tccgtgtttt
    20821 ttgggtagga cagtcgcgtt tgtgatttgt ttcgtgttat aatacaacta gttgtaaaga
    20881 aagacacatc ctttatataa aatgcgatgc aagaggtgag acaaaatgag atgtcccaga
    20941 tgtcaacata ataattcacg agtaatcgac agccgtcaag cagatgatgg acgtgcgatc
    21001 cgtcgccgtc gcgaatgtga gaattgttcg ttccgattca ctacatttga acgaattgaa
    21061 gctgctccgt tattagtaat caagaaaaac ggggaacgcg aagagttcaa tcgcgataaa
    21121 attttaagag gactcatccg ttcagcagaa aaaagacctg tagctatgga acaaatggaa
    21181 caaatcgtca accatgtcga aaaccgcgta cgcagtctcg gagaaaacga agtatcgacg
    21241 aatctaattg gtgaatatgt gatggaagat ttagttgatt tagacgaaat cgcttatatt
    21301 cgttttgcaa gtgtttatcg ccagttcaaa gatatgtctg ttttcttaaa agagttgcaa
    21361 gatatcgtgg ataaagcaaa agaaaataat aaagagaata ataaagaaaa caattaagaa
    21421 acaaaaagga ggcatttcct tggaaaatgc ttggaaagag cttcaaccaa aaaatattta
    21481 ccaaggaaga aaagcggctc cgctgagaga agacagcaag aacgccttgc tgtatcttta
    21541 tcagccacta atcggcggag aagccttgag tatctatttc accctgttat cagaaatctc
    21601 tcaagaatct ggcaaaggtc ctgaagggat gcatgcagat ctgcttagta gtctaggctg
    21661 cggtatcccg caattttatg atgcaagaaa aaagctagaa ggaatcggct tactggatgt
    21721 ttattttaaa gaagatagtg atctgggacc tcgttttatt tatgagctgt tagaaccact
    21781 cattcctaaa gcatttttca aagactctgt tctggctttt cttcttctgg aaaaagttgg
    21841 tgaacgacga ttccagaagc ttacccaatt ctttgaacct aaaaggcata cagcagaggg
    21901 atatcaaaaa atcacaaaaa aatttttaga tgtttatcgc ttcaatgaag cagtgtacgc
    21961 tgctaatcaa gaaaacatcg aatcgctgaa taaatctttt gaagaatctg aatcagtagc
    22021 attacttgaa gcagattcga cattcgattg gcagtttttg aatgattggc tggcaaaaaa
    22081 acatattgca agtcttgatg atccaatcat caaacaagtc gacatgtatc atcagcttta
    22141 cggtttcgat gaattgacac ttggcgaact gatcagtcaa tcttatgact ttagtgaaca
    22201 aaaagtatct gaaaaagaac tgcaaaaagc cattttggca atgcagagac gtccggtgaa
    22261 gcaaacaaaa gaaacagttg cggtttctga aaacagtaat gaaccctcgt caaacgaaca
    22321 tttgacaaac gcagcgcttc agctgataaa agaagcacag agcattccac cgatgaaata
    22381 tctggaagca atcaagtcag aaaaaggcgg atatgtttct aaacaagaaa actggttact
    22441 gcaagatctt gtttctcaat caggtctttc cagtagcgtg atcaatgttt tgctgaatta
    22501 tgtactagtg atcaagaata atgctagctt aaatgccagt tatgtaaata cagtggcaaa
    22561 tgaatgggca caaaagaaaa tcgccacagc agaagaagcg atccagcaca ttcggcaaat
    22621 aagtaatcaa gcaaaacaat caaaacaaaa gaagcaaaca aattatcaaa ctggcaagcg
    22681 aaatgttcga cgggaaaagc ttcctgattg ggtcaaccag ccaaaagatg aaaaacagat
    22741 cagcagcgag aaaaaagcag agattgaccg ccgttttaaa gaatacctgg caaaaaagga
    22801 gggtgatatc tagtggaaga cgtaggcaaa gaattgaaga ggatcatcag caaacgcaat
    22861 tatcaagaaa agtatgctga aatgatcgct gaagtcttaa atgatgcgga tgttcaagct
    22921 tttctaagcg cacaccaaga agaattgaca caagcggata ttgaaaaaag ttacgctaaa
    22981 ttgtatgaat tcgtgcaaga aaagcgtaaa tatcaaaaaa acgatccaac gatgatcgct
    23041 cccggctatg agccgaagct gacgttgaat tttcattatg tggatgtcac ttatgtacca
    23101 acggaagcat tgttagcacg gcaaagacaa gaagaaatca gaagccgagt aaaagcaatg
    23161 gatatgccaa aagatattca atcggcttct tttgaaaact ttgaacgtac agatggacga
    23221 ggatatgcga gcttagaagc cctagatttt gtagagaaat atactgctga tccaaaaggg
    23281 tatcataaag gactgtatct agtaggaagt tttggtattg gaaaaacata tttattagga
    23341 gcaacagcga gagaattagc gattgctgga ttcaccacga cgctagtcca ttttccgaca
    23401 tttgccgttg agatgaaaca ggcaatcgga aaagatcaag tggcagaaaa gttagatgca
    23461 gtgaaacgtt cacctatttt gatgatcgat gacattggtg cagatgcgat gagtagttgg
    23521 atacgagacg aagtattcgg tgttatcctt caatatcgga tgcaggaaca gttaccaacc
    23581 ttcttctcat cgaattttac aatggatgaa ttggaacagc atttgtccgt cactcaacgt
    23641 ggagatgaag agccgctaaa agcgaaacgg ataatggaac gcatacgtta tttgacaaaa
    23701 gaaatcgaaa tgactggtcg caaccgacgc aatggttgaa cagttgacaa gtccaactga
    23761 catttgacct agtagtaaaa gcaggtcagc gaatcattat atggacagaa atgaccggag
    23821 acaatcaccg caacaagtaa tgcagaaact taaacggagg attttttatg agggctattt
    23881 tttctagtat atctgtagtt ggtctatttt ttcttttagc aggctgcggt agcgcagata
    23941 gcaacacagg ttctgttgat tcgattgatg cgggtcaaac agtaaaaaca agcagtacga
    24001 aaacggagag acaaagcata tttgtcggaa cgattgaaag tatcactcaa gtagaagcag
    24061 aagaagaaac gcttcagttg aaactcgtcg atgtcatggc caaagaagat ccagcgaata
    24121 tgggaacgtc attcagcaat gacggagtga tcttaaatgc tactgctgaa aaaataagcg
    24181 tggacataaa tgaattgaaa atcggtgaca aagtccaatt tacattagtt gagatgccga
    24241 tcatgacgat gtctatccca ccgcaagttc ctggagattc gattattgat gtttcattga
    24301 acaaataacc aataacattt tttcaaaaat aagaaaatgt tgttttatag aacgaaaagg
    24361 tatatttttt aaggagatat gggaattttt ttattcctag tctccttatt ttatttggaa
    24421 aatgctataa ttatctagaa ggagtgaagc tatgaaccat ttagatttat ctcagcgctt
    24481 agccgcagtg ggtgactttg tccctgaatc cgctcgttta gcagacattg gatcagatca
    24541 cgcttactta cccgttgcat tgatattaag aggaaaaatc gaatatgcag ttgctggtga
    24601 agtcgttcaa ggtccttatg aatcagcacg taagcaagtc aaaaaagatg gattagaaga
    24661 ccgtatcacc gtacgccttg caaatggtct agatgctatc cagccacaag atggtattac
    24721 agctgtcacg attgcgggta tgggaggttc actgatccga gatatcctag aagctggcaa
    24781 gttgaatcaa cgcttaagcg gacaagaacg tttgatcctt cagccaaaca tcggagagcg
    24841 tacattacga tcttggctgc aagaaaatca gtataaaatc caatcagaaa aaatacttga
    24901 agaaaataaa aaaatatatg aaatcattgt agccgaaaaa gaacaaaaac cagttactta
    24961 caatgaaatg gagctgatgt tcgggccatt tctgcttgaa gagaaaagtg agatcttcaa
    25021 atcaaaatgg acaagagagc ttcaacaaag aaaagctatc cgtgaacagc tcaaacaagc
    25081 agctaatcaa gaggcacgtc aaaaacaaat cgagcaggaa atccaaatga ttgaggaggt
    25141 tttaaagcca tgacaatcag cggacgcact ttcatccaaa agtttgaaag ctattgtcct
    25201 cagtggctag ctgaagaagg agacccagtc ggactgcata tcggaacatt ggataagcca
    25261 atccaacgag taatgatgac attagacgtt cgtccagaag tggtcgaaga agcaatcaag
    25321 aaaaaaatcg atttgctgat tgctaaacat cctccaatct ttcgtcctgt aaaacggctg
    25381 gttactgatc agccacaaga aaaaatgtat gcagatttgt tgaaacatga tattgccgtc
    25441 tatgcagcac acacgaacat ggatattatt tgggatggac tgaatgactg gttttgtgaa
    25501 cttctcggta ttgaagtgga gagttattta gtaaagactc atgagattca ttataaaaaa
    25561 ctggccgttt atgtacctgt ggatcatgca cagaaaatgc gtgaagtatt agctgcagct
    25621 ggtgctggta cacaaggtga ttataccggt acaagtttta cctcgattgg acacggtcga
    25681 tttactccgg aagctggtgc acaaccagcg attgggaaag tagggaagac agaacaagtt
    25741 caagaggcaa aagttgaggt tattttgccg gaaactatcg aaaaacaagt gattcaagcc
    25801 atgcggtcag ctcatcctta tgaggaacct gcttatgatc ttttcgctat agatgaacca
    25861 gtcgaaatgt ttgggttagg acgagtaggt gaattgccgc aagaaatttc tatagaggca
    25921 tttgtagaac aagtaaaaga agcgttccaa ctagatggac tgagaatagt ccagccaaaa
    25981 aatgcaaaat cctctgtgaa gcgcattgcg atttgcggtg gaagcggtga aaaattttat
    26041 ccgcaagcaa tcgcccaaag agcagatgtc tatatcacgg gagatatcta ttatcatacg
    26101 gctcatgata tgcaaagcgc tgggttgatt gcaattgatc ccggtcatta tattgaatcg
    26161 ttatgcaagc aacgatttat cgagaaattt gaatcttgga aacaagaaga aaattgggat
    26221 attaactttt tcgtttctga aacaaataca aacccatttc aatttaatta aaaggagaga
    26281 atactatgta cgaaaatctt ttgccacgtt ttttacgata tgtcaaaaca gaaacacgct
    26341 ccgatgcaac aagcaaaacg actccatcga ctcagacaca agttgctttt gcgcaagaat
    26401 tgaaaaaaga attagaagag ttaggcttag ctgatgtttt ctataatgaa gataacggat
    26461 tcgttatggg aacattacca agcaatgttg atcatgaagt gcgttccatt ggatttattt
    26521 cccacatgga tacagcagat tttaatgcag taggagtcaa tccacaaatc attgaaaact
    26581 atgatggcga gtctacgatc gtactagatg cggaagaacg ctatacattg aatacaaaag
    26641 attttccaaa tttgaaaaat tatgaaggcc acacattgat cacaacagat ggcagtacat
    26701 tactgggagc agatgacaaa tcagggattg cggaaatcat gactgcaatg gagatcttga
    26761 tcaataatcc ttctatccct cacggtacca tcaaagtggc ttttggtcct gatgaagaaa
    26821 tcggtgtcgg agcggataaa ttcgatgttg agcaattcga tgtagatttt gcttatacag
    26881 tcgatggtgg tcctttaggt gagttgcagt atgaaacgtt tagtgctgct caagcaaata
    26941 ttacgatcca agggaaaaat gtacatccag ggacggcaaa agatacaatg atcaatgctc
    27001 tacagttagc aatcgatttt cataatcagc ttccagccga tgaagttcca gaaaaaacgg
    27061 aaggatacga aggtttcttc catttgatgg cattggatgg gaatcctgaa gaagcttcta
    27121 tgagttatat cattcgcgat catgatcgtg aaaaattcga agcacgcaaa gcacaaatca
    27181 cacatatcca agaagagttg aatcagcgat ttgatcaaga acgaatcaaa gtagatatgt
    27241 atgatcaata ttacaacatg aaagaaatca ttgaaaaaga tatgagcatc gtggaattag
    27301 cgaaacaagc aatgatcgag cttggtatct ctccagtgat cgaaccagtt cgtggaggaa
    27361 cagatggttc aaaaatctct tacatgggta ttccgacgcc aaatctattt gccggaggag
    27421 aaaatatgca cggacgattc gaatttgttt ctttacaagt aatggaaaaa gcaacagacg
    27481 tgattgtaaa aattgcagaa ttgaacacaa agagttaaaa tcgaaaaaga acagcttatg
    27541 acaaggcgtt cgtcccaatg atggaatgtc atctgtctaa ggctaaaggg caggacaatg
    27601 gaattggttg tcccgccctc ttttttgaag agtaaatagg aggtaaagaa tggaaaagct
    27661 gctagttttt tataacaaaa gttcagggaa agatgagggt gagaaattag cacgctggtt
    27721 tcaagattat gtaaaagaaa agcagccaga attatatgta gaactagctg aaactggccc
    27781 atcgattgat gatgcggaat tagtcaagaa agcagaagcc atagaagctg atactttagt
    27841 aattataggt ggagacggca cgattcatca tatcgtccaa gcgttccaaa aaacattatc
    27901 tcaataccat gtcggattac ttccaggtgg aactgtcaac aaccttgcac gtgttcttga
    27961 gattcccctc aaaaaagaag aagctgctga cgtgatcctg gaaggcaatg tacggaaaat
    28021 agactatggt caagtcaatg atgaagtcat tatctctaca ctgacaatcg gaatcttagc
    28081 agatacagca gtttggatca gtcaagaaga aaaacagcgt tacggctcgt ggatctttat
    28141 caagaagttt tttaagttat tgctgaagaa gaaaaaatat catttggatt tagaaacaga
    28201 cgaggagcat tggaaaggaa aatcccaact gttgacagtc acgatgtcta actccgtggg
    28261 cggttttaca aattttgacg actcagcgac cctagatgat ggaaaatttc atgtaacgat
    28321 cgtaccttcc ttagatattt tccgatttat tttttatttg cctagaatca tgagaggcaa
    28381 attctatacg atccccggca ttacttattt cacagccaaa cgcatgaaaa tccaagcgca
    28441 ggaaaaatct gtgggcactc gaacggatgg agacacgaca gatgatcttc cagttgaatt
    28501 atctgttgta tcaaaaggat taacagttta ttcaccaaag aaagaagaaa aagcttagaa
    28561 atagtagtta acagaaagtt ggaagaagag taatggatgt attgttacac aatcctttgt
    28621 ggttttacct tttcattgtg aatttttact tattttgtct gatggggtat gataaacatc
    28681 aggctagaac tagcggctgg cgtgttcctg agaataattt gatatttgtc agcctgttag
    28741 gcggtggttt gggaggattg atctctcgaa aagttttcca tcataaaact cggaaaaaga
    28801 agtttactat aggattcgct gcaggtgtac ttgttgattt gattctcatt tattttttcc
    28861 attaaggagc aggagatgtc gtctaaagga acgaaaacta aaatcattct gaatctgctt
    28921 ttgctgattg tgatttttgc cattatttat tatttaatca atcaatcatt tgcagatatc
    28981 tttgccgaat tgctgtctac cagtgttgtt gttttggcag cggctgttat attagggaca
    29041 gtttaccaaa tcgctgaagg gcgctcaatc aaagaaattg ctgaaccttt cgcgccgaat
    29101 tttacaacga aagatgggtt cttgacctct agctatattg cgttttaccg aatcgtttcg
    29161 tttggtacag gaacgctgat ctcggagatt tatttttata acaaaaaagg aatgaagcta
    29221 tcccagggag caggggtgac agcactccat atgattatgt acaaactggc agtgatcact
    29281 tatgcattag ctggcttggt catccaattc tctctttttt attctaatgg tccatcaatg
    29341 atctggttta tcatcgctgg tatccttttg acgatcgtga ttgttgcctt tttattggcg
    29401 atgtccgtca gcttgaatgt tcaaatattt tttgtcagct tatcgaataa gttatttaaa
    29461 agtgagcgtt tgcggaaatg ggtggataca tgcaatcagc agatctactc tttaagggaa
    29521 acggtccaaa ccattatcca agacaggact gcgctattgc ggatttatct atggaatatg
    29581 ttaaaacttg tattttggta tgtacttcct tatttgattc tgattgaaaa ccatcctaaa
    29641 atagattttc tactgaccat ttcgtttatc agctttgcag tagtgctttc aggggttatt
    29701 cctacgcctg ctggtattgg ttcctttgaa tttgtctatt tgttattatt cagaccagtt
    29761 gttggaacag ttgacgcagt ttcttcgctt ttactgtatc gtttcagttc ctttatcttg
    29821 ccatttctct atggatttgt gtatgtgatt gctgaacggc gaagagtgat caaagaagaa
    29881 ataatagaag taaaaaaaga gaataaagaa aatcaagggt aggtctttta taagatctac
    29941 cctttttatc aaatcaaaga aaaacgttat ggataagata attttacgtt tgtttggctc
    30001 tttttttata tacatacaat caattttgtt tttttaagat ttatataagt cgagaaaaaa
    30061 agtcaaaaaa ctatgtgtat attttgacca aaattgacca aagcgatata atagtttttg
    30121 taaagatcaa agaaataagt gatcttacct ttaattagga gggtatacct gtatgaatat
    30181 tgagaaaatg actacgacgc ttcaagaagc gattgctgaa gctcaacaga ttgcggtcac
    30241 tcgaaaacat caagatatcg acattgccca tgtatggaaa atctttttac aatctaatca
    30301 ttttggtcga aatttctata cggatgccgg attggatgtc gaatcttttg aacatgaaat
    30361 tgatcgtcta ctggatgagt atccagttgt ttctggtgga aacgtccaat atggacaaaa
    30421 cctcagccag aatttctttc gattattgaa tgaagcagac caaatacgtg aaagcttcgg
    30481 cgacgagttt ctttcaacgg aagtcgttat tttagcgttg atgaaattaa aaaattatcc
    30541 gttaactgtt tatttgaata aaaacggatt atctgaaaaa gaattgcgta aaaacatcga
    30601 agagatgaga ggaggagaaa gagtgacctc acaaaaccaa gaagaacaat acaaagcatt
    30661 agaaaaatac ggcgttgatt tagtacagca agtcaaaagc ggaaaaatgg atccaatcat
    30721 cggtcgtgat gaagaaatcc gtgatgtcat ccgtattctt tcacgaaaaa caaaaaataa
    30781 tcctgttctg ataggagaac ccggtgtagg gaaaacggca atcgttgaag ggcttgctca
    30841 acgtatcgta cgcaaagatg tgcctgaaaa tttaaaagat aaaacgattt tttcattaga
    30901 tatgggtgca ttgatcgctg gagcaaaatt ccgtggtgaa tttgaagaaa gactaaaagc
    30961 agtcttgaaa gaagtcaaaa aaagtgatgg acgtatcctc ttgttcatcg atgaaatcca
    31021 caatatcgta ggggcaggaa aaacagaagg aagtatggat gccggaaatc tgttgaaacc
    31081 aatgcttgct cgcggtgaat tacatttgat cggtgccaca actttagatg agtaccgtca
    31141 atatatggaa aaagacaaag cgttggaacg tcgctttcaa aaggtattag tcaaagaacc
    31201 aacagtggaa gatacgatca gtattctgcg tggattaaaa gaacgttttg agatccacca
    31261 tggtgttaac atccatgaca acgcattagt agcagcagct actttatctg accgttatat
    31321 tactgatcgg ttcttaccgg acaaagcaat cgatttgatc gatgaagcca gtgcaacgat
    31381 tcgggtagaa atgaactcta tgccaacgga attagatcaa gttactagac gtttgatgca
    31441 gttggaaatc gaagaagctg cactgaaaaa agaatcagat gatgcaagta aaaaacgctt
    31501 gaaaaatttg caagaagaat tagctgaact tcgtgaagaa gcaaatgcga tgaagatgca
    31561 gtgggaaaca gaaaaagaag aagtcaattc tgtttcagca aaacgtgctg aaatcgataa
    31621 agcaaaacac gaattagaag atgcagaaaa taactatgat ttagaacgcg ctgctgtatt
    31681 gcgtcatggt acgatacctc aattagaaaa agaattgaag gaattagaag ctaaagcaaa
    31741 agacagcgag attaagatgg ttcaagagtc cgttaccgaa aatgagattg ctcaagtcgt
    31801 tggcagatta acgggtatcc ccgtaacgaa acttgtagaa ggtgaacgag aaaaactaat
    31861 taaattgaat gaaacacttc ataaacgagt gattggtcaa gatgaagcag ttgatgcggt
    31921 cagtgacgcg gtaattcgtt cacgggctgg attgcaagac ccaaatcgtc ctctaggttc
    31981 tttccttttc ctaggaccaa ctggtgtcgg aaaaaccgaa ttagcgaaag cgttagctga
    32041 gaacttgttt gactcagaag atcatatggt acggatcgat atgagtgaat atatggaaaa
    32101 acatgctgtg tctcgtctag tcggagctcc tccaggctat gtaggttacg aagaaggtgg
    32161 tcaattaacg gaagctgtca gacgaaatcc ttatacaatc gtcttgttgg atgaaatcga
    32221 aaaagcgcat cccgatgtct tcaatatctt gttacaagtc ctagatgacg gacgcttgac
    32281 tgattcaaaa gggcgagtag tagatttcaa aaatacggtt ctgatcatga ccagcaatat
    32341 cggttcacag ttactgctgg aaggcgtgac tgctgatgga acgattccag aagcagtggc
    32401 tgaacaagtc aacacgctat tacgtggaaa cttcaaacca gaattcttga accgaatcga
    32461 cgacacgatt ttatttacac cattgagcct agacaacgtg aaaggaatcg ttgacaaaat
    32521 ggtggcgcaa ttggcacaac gtctggaaca tcaagaaatc ctgctgacaa tcagtgatga
    32581 agccaaaacg tggattgctg aaaatgctta tgaaccagca tatggtgcaa gaccattgaa
    32641 acgatttatc actaaggaag tagaaacacc actagctaaa gaaatcgttg caggacatgt
    32701 tatgcctaaa tcaaaagtaa cgattacttt acttgatgga caacttcatt tcaaaacaga
    32761 agagctagaa gaaatcgtct aatcttccat tgagactata aaagaaaaaa ggggtctgac
    32821 acaactagtg tcagacctcc ttttttcaaa taaacagtgt tccagaagta gtttcttcga
    32881 aaaataagcc gaaatttctt gaagctgccc gcttctgtca caacctcttt tattaggtat
    32941 ttttcacttt ttctaattta taactttcaa agtaacgctc atctttttta ctttgagacc
    33001 atgcaaacaa tcccattaag gcagcaccta tcgtatttgt cagcaagtcg cccatcgtat
    33061 ccatcaatgc tgctcgtccg acaaacagtg tgccatcaga agcagcaaaa cgttgaagat
    33121 tcatgcctaa gaactggtcg cataagaatt cccagaactc ccaaaacacg ccgcaaagtc
    33181 cagcaaacgc aaagccgaat aagaggaaca accaaggact ggtttttgat atctcagcat
    33241 ctttcatcaa gtaaccaatc aatccatagc caagagctgt caggaccatt ggactcaccg
    33301 catgtaagat tttgtcccaa aaagagatga tactgatcaa atgcatccct gtgcctaaaa
    33361 agacagagat gaacaagaaa aaccagtaaa acaaaacgat tgctgctggt attttaagtt
    33421 tgaaaacttt caaaatgact tgtggcatga aaatcaatgc aatccctaat aaagattcca
    33481 cgataaatgt gattccttga gaagtcgaat atttttgtgt gataaattca taaaaattat
    33541 agcagacaac gaatacacca aaagcaagta aagctatttg cacctttttg atttctttaa
    33601 tcactgaaag tccctccatc taaaaatctt tttacttctg aaagcaactc aatttctgaa
    33661 gaaaccactt ttccgttcaa tttgatcaaa cctattgtat ataagttcag gtagtgaaat
    33721 tgattttcag ctgtttcttg tagtgcagcg atttttttcg ggtgggttcc gccttgctgt
    33781 cgagtatcag tatataagcc gatcactggg atgcctttcg cataagccac accgatttcc
    33841 gatgctaccc cggcatcgat cgtcagccca tctagtaaag caatcattaa atcactagcc
    33901 aacacttttt ctgtgtcagc aagagcaatc attcgactgt ctgcataagc agttttgtca
    33961 ttgattgctt cattttcttg aggaagatag atcgaaagct cagaagagag ctctctgatt
    34021 tctttaacta actgttggtt atataacaaa tcacttttag caaacattgg tgcggcaaaa
    34081 taaattttca tctaaacatc atccttttta tcaaaaataa tcgctaaagt aagcttccat
    34141 gtttggaatg atacgctcta gtgacttcag tgtttcttca tctgtttcta accgttcgat
    34201 tcttgccaaa taagaagcac ggcgataatt catcatcaag caagtcaatg tttggatatc
    34261 cagtcgaacg gattttccta taggttcatt taagacacgg acttgtccct gttcatccca
    34321 tgttaaagcg aagacaccat tattccaagg agcgacagga tcttcaatga tgaaatgaaa
    34381 agcatcagct gttccaacaa acggaaaccg ttgaaggaat tcttttacat caacgatccg
    34441 agccataaaa tatggttcga tctgctcttt gatctgacta tcttcaatca aaaatgctaa
    34501 aggctcattt ttataaatat ctccatgtac ccagtagatc atggaaaaat gtgcggaaat
    34561 aaagttccat aagccatttc gagcttcttg atcaagatag aacatttctt ttacgtgaaa
    34621 tatttcttca gctacccagt agaacagaac acctcttggt tcatggttgc tatcgtagta
    34681 gacagcggct gtgcgctcat cttcattttc gaaacgccaa tactcttccc aatgaaaatc
    34741 actgcggaat aaagcaccat ggttttgttg ggcaaatttg tcataaacgg aaaatacgtc
    34801 tggatgatca actggtaatc gctcaaccat accacttact gggatttgtt taggtagctg
    34861 tgtatctctg attttaaagg aaagtttatc agacatgatt tcccatcctt tacgccgata
    34921 gtaggggata ctgtaaggat acaaataaga gatccattgc ttattcttgc gcatattatc
    34981 caatgcaacg ataattagat cttgcatcaa tccatggtta gcatattctg gataagttcc
    35041 aactccagtc acaccaccca ttttataacg tgcaccgtga atattgactt cacaaggata
    35101 gatagcgatt tgagagatca gtttattttc gtggaaccat ccgaacactt tcgatacttc
    35161 caaaatcggt tttttggaac ggataaaagc tcgtttattc tcaaacccgc tttcctcgat
    35221 gtctgcttca gtcacttgga acacatagga aagcaattca ttgaattgat cgatatgttc
    35281 ttgagtgacc ggttttaatt caagattttc tctaaaatct ttttgatcca ttttttcatc
    35341 tccatttatt agcttgataa cagtatagca aaattctaca aaaaaaactt ctatagctga
    35401 ctaattaaaa actctttaaa ttactgcttt tcgttggtat aatggaaagt gctgattata
    35461 tgaaaagagg agacgctatg gatataaaga aaatgaaaga acgccaagag cagattcgta
    35521 atttttcgat catcgctcat atcgaccatg ggaaatctac attggccgat cgtattttag
    35581 aaatgacgca cactgtgacg tctcgcgaaa tgcaagatca gctgttagac tcgatggatt
    35641 tggaacgtga acgtggaatc acgattaaat taaatgctgt agaactcaat tacacagcga
    35701 aaaatggaga aacatatatc tttcacttga ttgacacccc agggcacgtc gacttcacct
    35761 atgaagtctc tcgaagcctt gctgcctgtg agggtgccgt tttagtggtc gatgcagcac
    35821 aaggaatcga agcacaaaca ttggccaatg tttatttagc gttagacaat gatttggaga
    35881 tcctgccagt catcaataaa atcgacctac ccgcagcaga tcccgaacgt gtccgtcaag
    35941 aaatcgaaga cgtaatcgga atcgatgcta gtgaagctgt attagccagt gccaaatcag
    36001 ggattgggat tgaagatatt ctcgagcaga tcgtggaata tgttcctgca ccaagtggag
    36061 acttagatgc accgctaaaa gctttgatct ttgactctat ttatgatagt taccgcggtg
    36121 ttgttctaaa tgtccggatc acggacggta tggtcaaacc cggagacaaa atcaaactga
    36181 tgagtaatgg caaaacattt gatgttacag aggtcggggt cttctcgcca aaagcagttg
    36241 ctagagactt tttgatggtc ggtgatgtcg gttatatcac agcaagtatc aaaactgtcc
    36301 aagatacacg agtaggggat acagtaacgt tagcagacaa tcctgccgct gaagctttac
    36361 caggttaccg aaaaatgaat ccgatggttt attgtggtct ttatccaatt gatacttctc
    36421 gttacaacga tttgcgggaa gctttagaaa aactgcaatt gaatgatgct gctttacaat
    36481 tcgaaccaga aacctctcaa gcattaggtt ttgggttccg ctgtggattc ctcggacttc
    36541 ttcatatgga tgtcgtccaa gaacgcttgg aacgggaatt caatctagaa ttgatcacga
    36601 ctgcaccatc cgttatttac catgttaata aaacggatgg tacgactgct acagtagata
    36661 acccggcaga ttttcctgaa cctgtaacga ttcaggatgt agaagaacca ttcgtcaaag
    36721 cacagatcat ggtcccaaat gattttgtcg gtgcagtaat ggaactttct caacgaaaac
    36781 ggggagaatt cattacgatg gattatttag atgattaccg agtaaatgtc gtctataata
    36841 ttccgctttc tgaaattgtc tttgactttt tcgacaaatt gaaatcaagc acgaaaggct
    36901 atgcctcatt ggattatgaa atgtctggtt atcaaaaaag caagttagtg aagatggaca
    36961 tcttgctgaa tggagaaaaa gtcgatgcat taagctttat cgttcaccga gactttgcct
    37021 atgaacgtgg aaaagcaatc gttgaaaaac tgaaaaaact aatcccacgc caacaatttg
    37081 aggtgccaat ccaagcagct attggacaaa aaatcgttgc ccgttcagac atcaaagcct
    37141 tgcgtaaaaa cgtcttggct aaatgttatg gtggagatgt ttctcgtaaa cgtaaactct
    37201 tagagaaaca aaaagaaggg aagaagcgga tgaaacaaat cggctccgtc gaagttccgc
    37261 aagaagcctt catggccgtt ctgaaaatgg atgagcaaga tagtgtgaaa taacttataa
    37321 tcaatcgaaa aacctattaa ataaaccttt ttgagtagat gcaacactga ggattatctg
    37381 tataaaagat tttaaactgt catttggtta tcacggcgat actaaaatta acaaaattgg
    37441 aatatttttc ttgaagattt ttagctgtca gtatatgatg aaagcatctc ataggaggtg
    37501 cttttttcat ggttgataat tcaagtggaa gggttcttaa atctctaaga aaagagaaaa
    37561 aactatctca aaaaaagtta gctgatttag caggtatttc acaaagtact ttagttaaat
    37621 atgaaaaagg gtcaagaaaa atccctaaag acgtagataa tactctaagc aagattctga
    37681 atatagaaac tctaataaaa gatgaggaag ataagattga gattctcatc ggtaaactaa
    37741 ttgcatacag agatatgaat aagttactta acaaagagtt agctgataat ataggaatta
    37801 gtgaagtatt actcagttat gtgttaaata gaaagagaaa tccgtcaaaa gaaatgcaaa
    37861 aaaaaatcga tatttttcta ttaagtaatg aaaaagaaat tttgaaggag attaatcgtg
    37921 atagtgagat atttagttta tcaaaagacg ataaaattgt tatgggaaaa agaatacgag
    37981 aagtccgaaa gaaccgggaa gagacgcttg aaaaatttgg taaaaacttt accatctata
    38041 caggcaaaaa tgttataagt agatgggaaa aaggtattaa tattccagat attgaaaaac
    38101 taatgaatat tgcctatctt ggtaaggtca ctgttcctta ccttatgtac ggagaagatt
    38161 ataagaatat acttccaaaa gatgaaagag ttagcgattt taaaaagata aattctttta
    38221 gtatgggatt aaggatgagg aaaattagga aagattatta tctagaaagg gaggagtttg
    38281 gaaagctttt ttctccttca atttcaaaat ggtccataga taggtatgag aatggtagag
    38341 atatacccaa tactaatcga attatccaat atgcttatat aggaaatctt tctttagaat
    38401 ttttgattta cgggatataa aaatagttta cgtcgatact tattaagtta tcgacgtttt
    38461 ttattataga aaaaatttat aaaaggaggt ttcttgatat gataagaaac aaaaagggtt
    38521 tgttgaaagt tgctttactg gcagcttttt tctaagtaac tttttgacaa gctcaatggc
    38581 aacacaagcg gaagaagtaa tacaagaact aactgttatg aataacagct agataaaatg
    38641 ggctatgtat gttatccaac aatttagtaa tcactagaag cctagcgaaa gttcgcttga
    38701 taagttatag atgagtattg atttgtagtg tttccaaatc aaaagggtac agagccacat
    38761 gaaatatgtt gtcctctgca gcgtcaggat gggaatccat accatggaga ttcggagatc
    38821 tgtgagggaa tacttacgtg gttaatatgt cagttgtgtt ggacgtagta atggtcatag
    38881 tgggtagatt gactgaattc ttatatgaga aaatgaaacc aacaagaaga tagggttatt
    38941 tatacagaat tggggatctt ttctggaaaa gtaatcggat aatgcgagat tcgtacggtc
    39001 ttttttaaat ttctctaaaa aaaacggcat cgaatgggtt gggtgattga taagcaatga
    39061 atcatagact gatatagaat aaaaaatgat tctatttatc tttttacatc tatcgttttt
    39121 tcaagtagcc gcaaattata tcagcattca acaatttttg tatacaagtt ctagtaaaag
    39181 gatctgaaga aaaagttggt tgttgtgaag ataaaaaaag aatcaggttt tactgagttt
    39241 ttcttcaaaa tttgtgttat taggttagga caaagataag aagaagtatg aagatttaaa
    39301 aaaggaatga ggaaaagata gtaatttccg attattggag tttttttatt tataaagaag
    39361 aagcgaataa gttgtgattc ctagatttcg cgcgtgatta attaatgagc aaaaaatgcg
    39421 gaaagtttta gtgtttaata cacgaggaca aagtttctta ggtattgaag gcacacgtgt
    39481 aacggttgat gggtggtgtg attgtttcga ggttggaaaa catgttgaac ttatggcatt
    39541 tactgagcta aaagataaga acaacgtgga atttttcgag agtgatattg gttgggacga
    39601 tcatgaagaa gtttatggaa aatttatttt gcggaaggga aattcttata cgaatgggga
    39661 agcataagta gcgatttgtt agagatcatt gataggattg aaattgtcgg gaatatttat
    39721 gagaatctag agttatttga ggtgatagaa tgagtgatgg ttttgaacaa gtatcaataa
    39781 ttaaaaatca agttcgggag attcttagaa aaaaaggcta tttggtagat agttattttg
    39841 aaggagatta cgaaacatgg gtaggtgtct atgctcgtcc agagaataaa cctacctatt
    39901 tagatcctac gacgtcagaa gatgcctatt tacaaaatag gtatcgagta gatggtttta
    39961 agcaagactt tgcggagtgg tttgaatggg aaattgaaaa cggagaagta aaagaagaat
    40021 aagagtactt gttgtatcaa aataagccag tagaacaacc aaaccagtag ctagtaatga
    40081 caataatact gaggaatcgg atcattatgg tatgattgat atttctcttc cagaagatct
    40141 taagccagat cctgtaacaa ttggcaatag tgtcatgatt tttgattcat tagatgaagc
    40201 tatgtcatat ggttggaaag aaattaagga tgaaggtagt aattggtatg gcatgagatt
    40261 tggtgatggt gaagttgcca aaaaagctgg tattccaatt gggaaatgga cagttgattt
    40321 ccacgaagca ggttcttttt ttgttctgta attatagtgg gagggtaaaa tcattgatga
    40381 aatgtgttca gataagagcg ccagataaaa atagaagaga cagttcacgt cgttatcact
    40441 tttggtaacg gcgttttgtt ttattatata aaattctcag gaaaaggagg aattcttgtg
    40501 tatgcaaaaa cgaaaatgaa ttggttgaaa gcactcgcat tggtggcttt ttctcaattc
    40561 tgtttcttgg tgggaactgc tcaagcacat gcagaagaaa cgacggctat acaacctacg
    40621 atggaagcca ttgcccaagt cgcttctgaa gtgacagaag tccaaccagc agaagccggg
    40681 gtcccagctg gtgaagccac tgttgaacag gcccctgtga cagaagcgcc aacggtcaat
    40741 tccaaaacga ctctcgatca gacgattggg gaaacacaac acccagggaa tagtcctggt
    40801 acttcacaac cagttgaaga aactgcctca attacaaccc ctgcttcaga aacgtccact
    40861 ctagaaggag aaaaagctgc cgaagcaacg ccttctgtgc agccagagtc ttctgagaaa
    40921 caagcggaag aaaagaaacg aatagaagaa acagtggaac aaccagcggc tactgctgac
    40981 aaagaaggaa aaaatgagga aaacgttgaa aaaacaatct cttcaaccgc agctagtcaa
    41041 aatcaaccaa cgaaaccaaa caaagaatct acggctagta ttgaaaatca aaagaaaaaa
    41101 gagcagaaca ttccaaaaac aggtacacct acactgttag taacagtacc aaccaatcgt
    41161 tcggttcgtg ttcgccgtgc aaccaatgca gctgttttag gtggtcggaa aattgattgg
    41221 ggcgaaaata ttggtgttac ttctagtccg aacaatctaa acttcacttt aaattatatg
    41281 gttcgttttg agattaatgg acaagtggcg ttttgtattg agcctggtgt ctcagccgca
    41341 gaaggtcaag tttatacagc tactgctttg aaaaactatt tgaaaaattc aaatgtacgg
    41401 aaaaaaacaa gcttgatctc ttatttagga tatgtcacaa ataaagacaa atccgatgaa
    41461 caatacattg cggcacaatt tatgatttgg gaagctttgg gcacaaaaat cccaatcaaa
    41521 aatatccgtg ttgattatga tcgtcgaaaa gcagaaattc aacgtttgat taataacttt
    41581 ggtgaaaaag caacttttaa taatcaaaca catacggtaa aaattggcga aacgttgaaa
    41641 gtaaagaata aaaatgattt tttgaaatat gtgaaagaca ttcaaaaacc aaaaggtgtc
    41701 aatgtatcta ttcacggcaa tgaagtatgg attacagtca caaaagaggc accggataaa
    41761 gcaaaaattc aattgaataa aattaaagtt caaggtgcgc cattagccta tcgtcgtcca
    41821 ggagctcaaa caattggtgt gttacatcca acagaaccta atgcgtctgt tattaattta
    41881 caaattctaa aacaaggaaa cattcgtgtg tttaaagaag atgcggaaac tggtgtgaaa
    41941 gcacaaggtg cagcttcttt agaaaatgcg gtctatggtt tgtatcaagc agatgggaaa
    42001 aagattaaag aaattacctt gaaaaaaatt aacggcaaag tacaggcaga aattaaagat
    42061 cttgatcctg gcaaatatgt tttaaaagaa atcaaagcgc caaaaggtta tgtgctttct
    42121 gatgaagcaa ttgaaattgt tgttgaacct ggaaaaactg tcaatgcgac cgcaaaagat
    42181 caagtgatca aaggaaccat tgatttagtg aaagttgcta ataaagattt agtcgattca
    42241 acgaatccag ataacaaacc aaaattagct ggcattgaaa tcactttgac gtcaaaaaca
    42301 actggcaaag tggtgaaaac cgttgtgaca gacaatgatg gttatgctac ttttggtaaa
    42361 aataccgttg tctttgatac gtacattctt tctgaaacca aaggaaaaga agggtataaa
    42421 ctatttgaac cacttgaagt cacaatttct gaaaatgggc aaactttcca ttatgtttta
    42481 gaagataaag taattgaaca acgtcttaaa gtggtgaaag tggatcaaga aacaggaaaa
    42541 gtgattccac ttgctaatac agaattcaag atttttgata ctttagccaa tcgttatgtc
    42601 acaatggaga ttccaaatga tacagaaaca acggatatct ttaaaaccaa tgaaaaaggc
    42661 tttttcctaa ctaacggtac acttacttat ggaaaagatc gctatcgttt ggaagaaatc
    42721 aaagcccccg taaattacgt tttgaatcaa aacccattag tgttctcgat taccaatgat
    42781 acagaaccga tcaaagtgat ccattttgcg aaccgtcaag cacggaaaag tgtaaaatta
    42841 ttcaagtatg aagaatggaa caagaagaaa acgccgctcg caggtgtgaa ctttaccttg
    42901 tataacggta aaaatcaagc aattggtgaa tataccactg atcaaaacgg ggaaatttta
    42961 gtgaaaggtc tagttgccga tgactattac ttcttggaaa atgccccatt agaaagtttc
    43021 caaccaaata cagataaaca agcattcacg gttgcattca aacaaaatgc gccagatgat
    43081 ggggaaacgt tagtggtttc tgtacgtaat tacttgattc caccaaaact agaaacacaa
    43141 gcgtcaaata aagccgatgg tgaaaaagtg gttgatccat tagaaacgat cgtcattaaa
    43201 gacagtgttt cttataccaa cttgtttgtc ggaaaagaat acaccatttc aggagtattg
    43261 atgaacaagg caacgaatgc gccaatttta caagatggca aagaaatcac aagtaccttg
    43321 gcctttattg cagacaaagt caatggcaca aaagaccttg aatttgtggt taatgctagt
    43381 gttctgaaag gtcaaacgat cgttgttttt gaaaaacttt tccgtgatgg cattgaagtt
    43441 gcagcacatg cggatatcaa cgatgaagcc caaagtgtga aagtgaataa tccaaccgtt
    43501 cataccacgg ctgtctttga agacggattg acagtcgcag acccaacagg attgtttacc
    43561 ttaaacgata ccgttgaaat taccgagatt cttccaggaa aagcatactt ggtcaaaggg
    43621 atcttaatgg ataaagcaac cggtgaaccc ttgcttgtgc atggaaatac ggtagaaacg
    43681 agtgttggct ttattgccaa agcagaaaat gaaacggtga tcgtaccatt tacctttgat
    43741 ttgacaggta taaatggtcg tgaaatcgtc gtgtttgaaa gtctttttag aaatgatgaa
    43801 gaactagcaa accataaaga catcaacgac aaagggcaaa cggtacgagt aactaaccca
    43861 agtgtacgta caacggctac acataaaccc actggcttga aagaggttaa tccattaacg
    43921 aaagtcacca ttacagacgc tgtgaaatac cacgatttgg tcgttggaaa aacatacaca
    43981 gtcaacggtg ttctaatgga caaagtaacg gaaaaaccag tgctagtaga tggaaaagaa
    44041 gtcacaagta ccttaacgtt tgtggcagaa acaacggatg gtacagtcaa tctagacttt
    44101 attctagacg cacgtgcgtt gcgaggcaaa gaagtcgtgg tctttgaaga tctgtttaga
    44161 gaaggcgtat tattggcttc tcacgcagat attaccgaca atgaccaaac catcaaaatc
    44221 agtaatccaa ccattacgac gaaagcgacg aataaaaatg gcggaaaaga gatcttggcc
    44281 ttgccaaatc aaactgtgct tgaatgggtc aaagtagacg gtcttgcgat tggtcaaatc
    44341 tatcgcttaa ttgttcaagg ctacttaaca ccagacggca caccatttga aggcactcat
    44401 gcggaaaaag tctttgcggc cgataaagaa atgatggaat tcttatttga attcttagtg
    44461 gacggtcgca atcttgcagg aaaaggcttg agttttgcgg aatggctcca agcgaaaacg
    44521 gaagatgaga aagaaacgtt tgaagaagtg gcgaaacaca atgtagatct aacaaacaaa
    44581 gatcaaacgg ttcaaattgt ggaagcgcca aaaccaccgc aaccagtgaa accagaacaa
    44641 cgggttaaac cagctactgt tgtaccaatg ttgccaaaaa caggtgaaca aacaagtagt
    44701 atacttatgg ttcttggatt agtagtatta gtcattgctt taggtataac actttataaa
    44761 gtacgtaaag ccaaagatta gtcatgagga acaagcggtt aggattttta accgcttgtt
    44821 tgattgtaat gtagaaatat ttagaattta ttttggtttt taagaggagg aaaaacttta
    44881 tggcagaaaa agcattgcgt atgaagaaag agtttttagg tcaagtattt ttattgggtt
    44941 cacgggaacc taatccacca aaggaaatta atggtgtgtc tgggcgatat gttcaattac
    45001 aagcagagtg ttcgcgagaa gaacagcctg ctttttttgt ttatctcaca gctgaagagg
    45061 ataaaagatt acgattacca gaaaaagagg tgcgtatttc atttgaagaa gcttattttg
    45121 tttttcgtaa agaacgagtg aatagtcgtg aaacaaatga tatgggacaa acagagcgtc
    45181 gaacaactgg ctatcaagat gttggtgtct ttttaactgg tgtaaaaatt ggggaggttt
    45241 tgtaagatgg gattaaaatt tccaaataat tatgacatta cagaagcatt agatgaaact
    45301 tgtttaggag ccgtacgctt tggcgcatta gaagagtctg atcgtgtatt tgataatgaa
    45361 acaggcgatt atacgggaga aattcgatca cagcgagcac aattagtttt tggaaatcca
    45421 gatgaaccaa agattgcacg acgagttaaa tttccagcag atgtagattt gactggtttt
    45481 aaacgacgtg atcctgtgaa attaattgat ccagaatatc atgtggtata tattccagca
    45541 caagatggca atcgtgaata ttcagattta gtgatttatg cgaaaggatt agagaaagta
    45601 gaagctccaa caaataatcc taatatgaaa caatcacaag aaaaaggttt agatcaaaaa
    45661 caaccaagtg ttgattctaa ggaaaaagag aaaaaataag gtttttttga aagaatagga
    45721 aggagtcttc ctattctttt tatctaagat agaaggaagg ggagattttg aattcagata
    45781 aaaccaatca aatactttga gagattgtgc ttgttatcaa aatatccaac aattgattga
    45841 gtattttgga gacaatccaa cgatttttgt acaaacaaat gcatatattt gtgcggttat
    45901 tgggcagtgt atgtttttac gtgatcttgt tcgtttttca ttaccgtacc agtggaaaca
    45961 agatcatcag gaagtgattt ggattcgtat agtacgaata tgtaatatgt gtgcacaccc
    46021 ttataaaaat cgattaaatc tttttcgatt atgttttttt actaaatgtg atattcctgt
    46081 attagttgct ttttgtcaaa agtttttagc acaggaaaag taaaaacaga aaggaggaat
    46141 gtgacaattg aaagctcatt ttttcaagta tcgtggtcgg cgaattcgct atttcaatcg
    46201 ttatttatgg ttttgctatt atggtttctt tttgtttcca tttttgattc tgttaggttg
    46261 gtttagttgg aaagtatttt atccacgttt aagtacgttt tcgaattggc aaatgtatct
    46321 tattcctgga ataagtattg tgttgtattt gttgctggtt agtgggttaa ttttagggtt
    46381 gatgcattgg tcgcgactaa aagaaggata ttttgcctct gtttattggc gtcagttact
    46441 tgttcgaatg ttaattgaca atcggtttgt ttatacaaag aaacaagtta gtgagaaaca
    46501 aacaagggaa aaaatgagat taccaaaagt ttatttttat caaaagaaac aagaattagt
    46561 ggtttctttt cctttagatg gtgggcgttt tcacgaacga tttttaaaaa tgggtcattt
    46621 gttatctgaa gtatttttgc gtgatttaat tcgtgaagaa cgagaaaaag cccgaatcaa
    46681 ttatgtattc ctttcagatt ctggtcggat tcctattgat caatgtatag cagaaaatgg
    46741 acgtattcat ttaatgaaaa ctttggattg ggtatatgat caatcaccaa atatgttgat
    46801 tgctggtgca atcggtggtg ggaaaaccta tttattgtat tctttaattc aagcttgttt
    46861 aagtgttggg acagtagata tttgcgatgg aaaagcggca gatttagcag cattaggtga
    46921 cgtcgatgta ttcaaaggac atgtgtttta caaaataaat gaagaaatga ttatttgttt
    46981 acgaaatgca ttaaaagaaa tgaatcaacg gtatgcctat atgaaaacca tgaaagatcc
    47041 taaatatgaa ccagggaaaa attatgctta ttatgggtta ccaccgcatt ttatcttttt
    47101 tgatgaatgg gcagcttttt atggttcgtt ggatatggaa gcgagaaata gagtcgataa
    47161 attgattcag ccattagtat taaagggtcg tcaagcaggg atgtacatta ttttagcaat
    47221 gcaacgacca gatgcagaat attttccaag tggtgttcgg gataatttaa cattccgtat
    47281 ttctgttggt cgattgtctc ccattggtta tttaatgact tttggagaag attttaaaaa
    47341 taagccattt tacaacaaag atcaacctgg tcgtggatat gcttttccag gatttgatgt
    47401 acctgtagag ttttttgcgc catttgttta caaagattat cactttatca aagaatttga
    47461 gaaatttact gaaatgattg tctatgattt tacagtaaaa gaggatagtc aagatcaaac
    47521 gatgggagat gataatcagt tgttacaaga acaactagag cgccaaatgt atttagcaaa
    47581 agatccaaaa ggaacaagtt tttctgatgc gcatattttg taatcaacta aggaggtgaa
    47641 gttaaatggc agagagttgt tattatagag tagctacagc aatacgaatg attaatcctt
    47701 ctctttcttc cagaacgttt tatgattggt tgaatcgtat tgaacaagta actgattacc
    47761 gctttttgcg caaagaacgt gtttttacag gaaaagttat taatcaagta ttgctaacga
    47821 aaaaagatat agaacgattg actcgattgt atcattatcg agtagattta gaagaggatt
    47881 taactttgtc aatttatcgc gttttttctc ctgaaaaata tagtgaaata acaaaattag
    47941 atcatttaat tttgtagtta ttatctatcg ggagggctct agacgtagtc tggtagccgc
    48001 actctgcctg gcggtgcgca ttaaggctgc gaagcatggg cctataatgc gcactcgcta
    48061 gcagcgtgtg cagctcacaa agaggtcgtg cgcttgcgca cggcctcttt gtgtaaagcc
    48121 ccccgatata taatatgggg ggcagaaata acataacaca tagaaaaaag ttttataaac
    48181 ccttttgtat caagtgatta tctaaggtca gcagttgtac tacttttccc aaaaaacgag
    48241 ggggactagt tgatatatcg gtgtttctaa agggttaaaa aaatcgattt tgttatttta
    48301 taaaaggagc gagaaaatga caccgattga gctaaaaagc tacagaaaga agttaagtgc
    48361 aattcataat ataagtggag ataaaaagcc gctatcacaa gcaagatttg cgcaattgat
    48421 gggctgctca aaagattaca ttagaaagat ggaacaaggg aaaagaaaaa tcccagagga
    48481 ttttgaacaa cgaatcaagg aacgctttcg attgtatatg aaaagcggaa tagatcttcg
    48541 agcaatgatt gattatttgc gtctttcctt ttttgggaca gactacaaaa cagtgattca
    48601 acgtgtatta cgaatggatc tgacagaatt tgaaacacgt ccaacgggct tgtatctttt
    48661 tgactgtctt tctgttcgtg ggaatatctg ggtgttctgg cattcaaaac gaactgtaac
    48721 agaaaatgta cttgtgcaat tttcaggaca aggttgccgg gaatatgagg aagtcatgcg
    48781 tgaacaacaa acagattggc gaacatggct atattccatt tggaaaaatc aaggaaagtt
    48841 ggaagctggt tatacacgtg tgcaatgtag ccgattcgat attgcgttag atgaactttg
    48901 gggattggaa acggaagaac atttcgatct ctttgaatta ctagaaaaac aaaaagcagg
    48961 tttattagaa atggacttta agagattcca gaatattggc ggttgttttt tagatgatgg
    49021 ctattttcga agtgaaggat tatctttgta ttttggatcg cgaaagagtc ctctcttttt
    49081 taatttttat gagaaacgtt ttgaaattgc gaaccgagaa aaaatttcag aattagaagc
    49141 attaacgaaa tatggtattt ataatcgata tgagttacgg ttagccaatg agaaagcaac
    49201 acaagcagta gaagcattta ttttaggtga ttcaccgaaa cgtttaggag agattggcgt
    49261 tggtttaatt aatgcaaaac ttattgtttg ggatagactg gaaagtgatg cacggattgt
    49321 tgataaacga tgggcaaaat tatttcgttc gatggaagaa ttggatttta cagtaaagcc
    49381 agaaaaattc tcattagatc gttcagaacg ctggtttttg aaacaagtag ctccgacatt
    49441 aaagttgtta caagaagcag atcgtatttt aggaagagac tttgtacaag aagggattga
    49501 taatgccgaa ctaaatgacg agcaacaaaa ctatctagaa tggatgggaa cgtcaggagg
    49561 gaaaattgca tgaatgcata tacgacaaca gaatggctgc gcctgttgga tttaaaggct
    49621 gcaatcgaag cattaaatga aaagatggtt gatttgtctt attttcgttt tcgagttcct
    49681 tatattgaac aagcggtaaa agctggacgt tatcaggaaa aagagaactg gcaagaaatt
    49741 gcacgcttat tagaagttcg taagggatac gaacaagaac tcgaagagtt ggaatttagc
    49801 cgaaggaaag gaaggctaga attcattcgc ttttatcgat tttcattgcc aatacctgcg
    49861 attttagcgg ttaaaaaagg ctgcgataaa atgaagatat atgaaaactg tgtggcagca
    49921 cttagcagcg aaaaacctct tatggaagaa atttcattgg tgactgtcac ttgggaaatg
    49981 agtcgccagc caacagaaga acagacatat ctttctttag aagagattga gatagaatta
    50041 gaggaaattg gtcgctatgc cacttgttct acctattgtg gatcggtcat tagtattgct
    50101 ggtgtgattg tctaaatgaa aaaaattatg atttatgttg gtgcgtattg gtcacgtgat
    50161 ccaacagtat tagaaaatcc agaggcggta cactattgct tgcgccaatt attctatctg
    50221 tataaagaac gattagaatc gttgattcgt cagttaccat atactgacag acgtttagat
    50281 gaacttcttc taaggtatcc agcaatgtat aaacgacgaa aaaatagatt gttaccagaa
    50341 gagtatccca ttgaaaaaca tgaacttgaa gggcgatttg tggcttattt ctatgatgat
    50401 gttcgtatgc gcttagtaga acaacgaatg gaaatagaaa atgatcgcta ctattttatc
    50461 aattattgta agaagcgtaa gtatcaagta actgatgatt tttatgattg tattttacaa
    50521 gatggggaag tgattctatc caaaattgct ccaagttttc gtgaacttgt gccgattgat
    50581 tttttgaaaa aatgtcattt gcggattctt ccgtaaaaaa gagctataaa aggaaagaaa
    50641 agtagaagcc aaatcggttt ctgctttttt atttttttta ggaaggagaa gatggtatgt
    50701 cactggaatt tttaggagag ccaattgaaa aggaagagtt cgtttcgcat tatatggatt
    50761 tgtttattca ggtgataaaa aactttgtgc gattgatgaa ttttatccac gcgaacaaga
    50821 ctatctagcc gctgaacgaa taaaaatcag tttattatgg gaaaaattca cagatgaaaa
    50881 taaccgaccg ccagattatc gctatttatc agattgttta acgaataatg tgctttctaa
    50941 agaataccta tttcacaaac gtgagaaaaa tcaaatgtcg gttgaacatt tttgtgattg
    51001 ttatattgca ttattgcgta gtcaacagtt attaacagta gaacgatatg gtgcagagtt
    51061 tggttatgtc ttgcaagctg agcgtcatag agctacaaga tgctatgaaa aagaagatca
    51121 agtgattgat ggctatgaag aattatgtat tcgaaacaat cgctatttgc aacaacgttt
    51181 atatgaacaa ttgatgatgg atttttcaaa tctctataga gggtatgaat gttcgatgat
    51241 tcaagaaagg tagaagaaaa gggggaattt ttatgtggcg attattattt ttggtggtat
    51301 gtggtatggc attgttctat gtgtatcgtg tctatctcta tccacgaatg gaacgatgga
    51361 caagttggta tagagatcct ttaaaacaac gaaaaggatt gaagcggtat cgttatgaat
    51421 tacttgttga attttcggat gggcgacaag cacagtatta tttttttgca aactatccaa
    51481 aatacaacac cagtgaacta ttgattcaat tattcaaaaa taatccatat gttgggttag
    51541 aagaaaacgg acgggagttc ttttatcgtt cagataatat tagtgcggcg tctatgaaca
    51601 aaacacgaat tgcataaaaa attggaggaa taatcatgaa aaaaacaaca ttagcagtcg
    51661 taacaacact aggaatttca ttattttcgt ttcaattagg gagttcattg gtttatgcag
    51721 atgaaactgt agaaacacct aagtcagaaa ttgtagaaac attgccaggg gaaggattac
    51781 cagatgttga gacagagcta aatggaggaa caacggaaaa accagcagaa cctgaacaat
    51841 tgcagtcaga gaaacctgaa aaagagccag tgacaccaga accagagttt cctgaatcaa
    51901 ctttaccgac tgattcgatc gaagaagaag gtgtgcatag ttcaacaaca acggattcaa
    51961 gtatagtcac aactccggaa caatcaggaa caaccagttc ttctgaaaag aatactgatt
    52021 cgtcaagtac ggaacagcca acgatgtcgt ctaccagtga agaacaaaaa gaagaaccga
    52081 aacaacctgt tgaaaaatca gaagcaattc caaaagaaaa taaacctatt gttccagcaa
    52141 aagaagtcac agtatcggta accccaagcg gtgaaattac gacgaatact tctcaaggaa
    52201 tgagtgtacc gattgtcact agtaatgtag aggaattgac ccatattcca acaccaacca
    52261 ccccattaaa agtagcaggt gatcaaacaa ttgttggtgt aaaagatggt attccattaa
    52321 tccaagatag tgaagggaat ttggtaaagg atttgtcgat tcctgtaaag aaacttccaa
    52381 gtggcaatat tgaaatcaaa acagcagatg gaaaaacaaa agtcttacca aagactggtg
    52441 aagaaataca tgttgcactt tctgttctag gaggagtgtt gacaagtatt gctggatttg
    52501 ttggatataa aagaaagaga aaaggaatag aaaatgaggg taattgaatg gactattttt
    52561 cagaaaaaca agcttatcgt tgtcaatcgt acgtactagt aaaaacatac tagaaggagt
    52621 agcttatgaa aaaacgacaa ctacggcgga aagaaaaagt ttatacagag aaagtaccga
    52681 agcaaaagaa aatccattca aaaaaagcag tgaaatggat ttggtgtttg gttttatttc
    52741 tttgtttttc agggggcttg gcattttttc aatccatgaa aacgaaggtt caagtgtcgt
    52801 ttttgaaaga tgaaatccaa caattacaaa agaaagaagt acaaagtcgg tcagaattaa
    52861 cgtacacacc tgaaattgaa tcctttatga atcgttttgt tgctttgtat atgaatacat
    52921 tcgataatca tgaacaagaa caacaacgtc aagaaacatt aaaaaaagag ttttatgcac
    52981 aaaactttat tcaagaacca ggaagtgttt caggtgttcg aaaattaact gctgcttcgt
    53041 ttattggatt aaaagaaatt gaaaccattc caactgctag ttataaagta acttatgata
    53101 ttcgctcgat gaatccagag agtaagaaag aaacaagtgt gacaatcaca caagtactca
    53161 atcttccctt ttctatttca aacaagggct gtcgtattat tgcttatcct tattttacgg
    53221 cactaccaaa gaatacagaa aaacaacgaa tgattactta tgatgacaca ttatacgaaa
    53281 cggttgatgc gtcggaagcg aaagatgttg aaggatttgt ggaagatttc ttagataagt
    53341 atgcgaaaaa caatgcaaaa gatatgtcat acatgatgaa agaacctgaa ggactcaatc
    53401 aaacagctaa agttgatcaa gtagagatga aagtattgcg ttataaagaa acgaaaaaac
    53461 cttttattgt aaaagcaacg gtcgtctttc gagatggtga tacgtcactt ttacaaaaag
    53521 aacaaatgac gattgtcatt acgaaaaaaa caaatcagta ttatgttgaa aaattaacac
    53581 ataattggtt ggataggaaa ggagaagaac ggaaatgaca ctgaagggaa ttgtagattt
    53641 tatattaacg caaggtggct attttttaat aatggtggtt gtttatctgg gattgcgaaa
    53701 ttttatgaaa tcaaaagtag gaaatgcatt aatatctatc gcagcaggtg ccgcagttta
    53761 tttcttctta aatgatccaa cacgtgtatt tgatgcgttt ggtaaaatca ttgaaaaatt
    53821 atttatggat taggaggata gtgaagtgga ttgggaacct tatgattatt cgattgttta
    53881 tgcggaacct tatcgcgtac aacagattac aagcaattgg cgtcttccat ttccagttgc
    53941 attagtcaat gcagcaactt ttttgttggt cgtaatcttt gaatatttat ttttacgttc
    54001 atttattggt tgggtcattt ctttttttcc accagcagga gttgtttttt atataggact
    54061 cccctattta tgtgtgttag cactggcaaa actaaaacct gatggaaaaa aagtgcattt
    54121 ttatttatgg gattggtttt gttatatgat tcgtatgatg aatggtgatt gtgtgtatta
    54181 taactgggac aaggtatcaa acaatgcatt ggaagaatta ctttttgtga ataagtatgt
    54241 ttatttagag gattagaaaa agggacaatc aactggttgt tcctttttta ttgggaggtg
    54301 aaattcattg gtgcttgtaa aagaaccagt aaaagcattc aagaaaaatt gtttgttaaa
    54361 tggagaggat tgtatctggg cctactatca tgtttttcca cgaacaattt caaaaaacac
    54421 accaaaaaag acacaggaaa taaaagaaat gatggctcgt ttactgttgc ttttagcaga
    54481 ttatgaagat gtggagttgg tgatgtatcc acgaacaatg aatttacgga cgaagtttga
    54541 cacattagga aagggatttt ctcccgatag tcaagcaatt ggtgcgtatt atgcaaaaga
    54601 aacagtgaca ttgttggaac gagaaggtca agtctatcgt ccttcattta ttttaggaat
    54661 caaagtcaaa gaaaaagcaa cggtggagag ttttcatgat gtaataaatc taatctggtt
    54721 agatttagca ggaagtttag cacgcttatt tggattagaa gtagatgatt tggaaacttt
    54781 gttttctgaa agtgatcctt atgtaaaaga agtgacacaa ttactttata gcttttctat
    54841 tcgtccctta gtaaaaaaag agctgttgta tctcaatcgt ctgcaatata ttcgaggaat
    54901 ggctcacaaa gtagaagaac aaaataattg ggaagtactg aaagacaatc aaggaacgta
    54961 tgtacgtata ccgaaggaac ataaaggcct tcttcaatta gaagatgagt tagggagtag
    55021 ttatttagca ttgttgccta ttggggaaac acctgaaaat atgagaaatt gtgatctatt
    55081 tcaatttgct caggatcttt ctttcccagc agaattgcga atgaaaattc actatccacg
    55141 cttgaaagga cagggaggta ttggtttaaa actgaattgg ctatcggaac ggttcaaaac
    55201 agagcataag gaattggttc aaaatgatga agaacctagt gaacgcttat taactgttcg
    55261 aggattagta aaacatttaa agcaacgagt agataatggg caacctgtcg tcgattggat
    55321 cgcatgtttt attgtatacg gtcaaacggt tgaagaagtt cgtcaaaata gtgcaacggt
    55381 tattcaacaa cttcatacga ttatccatat ccaccgtgca aaaaatgatc aacgagaatt
    55441 gttctataaa tgtttattag ggcaaccatt gggacggcag ttacattgga agcaccgaac
    55501 aactgtagaa gcagttggcg aatggttgtt ttcagcagta tcagaattag gtatggaatc
    55561 cggctggtat attggtcggc aagatacatt aggggatggt ggttctcgag gagaaaaaac
    55621 accattagaa gaattaattt atgcgtcaaa tcgttttgtc tttttgaatc ttctagccat
    55681 tgcggaagga atcaaaggtg cgttgtttga tgcgcctcat gtagcagtaa ctggaaaaac
    55741 cggtaaaggg aagacctttt tagttggctt gctctttttg tatagttcgt ttatgaatgt
    55801 acaaagttta tttgtggatc ccaaaggaga aaagcgcaaa tggtttacga aactcattca
    55861 agacccgtat tatcagaaac attacccttt gtttgtagaa catttgcaaa aaatgagtta
    55921 tgtcacgtta gatgctacaa atccccgtaa ttatggtgta ttagatccaa ttgtttgttt
    55981 atcccgagta gatgcgaaac aagtagccca ggatatgatt gatgagttaa gtccgttagg
    56041 taccaatcac cttttaaaag gggcggtatt aaagggaatc caagaagttt tagttcaaaa
    56101 agaagccgga caacaagttg gcttgatgca tgtggtcgac tatttagaac aaatggaaca
    56161 aaaagaggtt cgagaatatg gtgagttttt acgcttgacg gtagaagatt cgattttacg
    56221 tttaggattt tcttatggag aaaacccggg attagacttt aatgccaaaa caacgatttt
    56281 agagatccaa gatttgaaat taccaaatga caatgtccga ccagaactat atacagatgc
    56341 ggatcgaaag tctttgtgtt tgatgattag tttaggtcgt ttttgtgaaa tgtttggaaa
    56401 acgagatagt agtaagaaaa cagcgattta ttttacagaa gcatgggtat ttaataattc
    56461 gaacgcagga cgtagtatta ttgcagcaat ggcacgtgtg gggcgttccc agatgaatca
    56521 attagtgtta gatacacaat ttattggtga cttaggttca gataaagaaa aagggaattt
    56581 tggtgtcgtc tttgcttttg atgaagacag tgagcgagaa aagattttga atcatttacg
    56641 tttggaagta aatgaagcga acttagctga aatgagccac atgattaaag gacagtgttg
    56701 gatgttagat ccctatggac gtgtaggaaa actcaatgta cacagtttgt ttgaagaaat
    56761 gaccgctgca ttacaaacaa cggaaaaaac aagtcactct caagtagaag aacaggatac
    56821 gttaatcatg caatagaaat gaggtgaaac aatggcttat ataaagcata aggaaaagaa
    56881 atggtgcgtt ttgttttttt taacgattgg attcggactg ctttttgttg gtggattggt
    56941 gtatgcggca gaaaagcagg tggatcaatc gatctatgag attgggaaat ttcatattga
    57001 taccttttct tcttatttat ctgatagtga attttcatta ggcaaaatgt tatttggggc
    57061 aaatggcaca gattttctaa aaatgatgac gaatatgttc tttagtttaa gtaaattgat
    57121 ttggcaaggc cttgattttg tcattgagaa gctctatgaa ggagctgcaa tgaacgagtt
    57181 aattcaccag tttttcactt tttcggatac tatttattca aaaatatacg atcctattgg
    57241 tgcggggatt gtcgtcttgt atgtgttata tctatttact cttcgtatat ttagagggaa
    57301 acattacgca aaaatggtgt ttattcgatt tctcttcgtt gtcatttttt caatggtttg
    57361 gtttggctat ggtagtaacg tacctagtaa aggagaagct tttaccaaag ggttaaatga
    57421 tttgtccgtg gaggtagaag gctttatttt ttctgctaca aatagtctag atgaattggc
    57481 gacaaaagat gtcaatggtg ttttagtgcc aacgacacaa aaggaagcca ttcaaaaagt
    57541 gcgccaactt tattataaag cggctgttgt tgatccgtat atattgttaa attatgggac
    57601 aacaaattta gaagaattgt atcaagcaga gattgaacca caagaatttc tagccaagga
    57661 agcgtcaagt gaagaattat ctgatattga gacaaaagtg accactgctg caggagaaga
    57721 tagagggaaa aagaaggctt atcgtgtcta tattcaacca actaaagctg tttataaagc
    57781 agtcgttggt tctatggtgc cattgcttaa tctaagtatt ggattaccac ttgtagtgat
    57841 tggcatgatt cgttttatct ttcaaatgtt ggtgttgtgt ttattacttg tgattccttt
    57901 ttcattactc gcttcttttg ttccagtatt tgattatatg ctcatgaata ccttaaagtc
    57961 ctttttgggc ttgatgtttc aaaaatcttt ttacagtgtg attattttgg tggcattttt
    58021 gatctataac atagtagacg atttaattcc aatgaatact gtttttggtt ttttaggaaa
    58081 tatgtttgtc aaagcactcc tatcaatttt actcattgta aaacggaaag atttattaaa
    58141 gaaactaggg ttaggagctg cagatcaaac tataaacaac acgaaaaaca tagcaagtca
    58201 ttctttgtct caaatgaaac aactgcctgg tcaactatca actgctggac aaaatttggc
    58261 aatcaaaggt gcaggattag cagggaatgt gtatcgagca acgaatccac tcgcttctgc
    58321 agcgatacat ggatttcaaa agtttcaaca aaaacgtaca ccacaagaat cggtaaaagg
    58381 gaggcaagtg gttaatccct ttgaactagg tgggcgttca aatcaagcct tgccttatag
    58441 tggtcgtcat gttcgttatc atggggtaga gcctgaaatg tcttctacca aatcgaaaac
    58501 agagtggaat tctggtcttt caaatggttt gattccaaat tcgtccatga attcagtaag
    58561 accaaaacaa caggtacaat cattggcaca attgagtaag caacaaggga ataatcaaag
    58621 aaaaccattg ttaaataaag gtatcgcttt tgttggtcaa tcgattccgt tgccttctgg
    58681 aaaagtaccc gtgccacaat taacagctgc tggttctctt tcacaacaga ttcgccaagt
    58741 gaaaaatcag gcgaaaaatg ggagttatcc agcaatgcag cagttattga accaatactc
    58801 tgttcctaat tcgtcggtag ccactctatc aggaaatcgt tctgtgcaac aaccggggca
    58861 acgttcgtct gaaagtaaac cgtcgatttc cgcaccaaaa tcgttacaac ctgcattttc
    58921 ttctttagat aagccaacag agcaatcgga aaaaatagaa aaggatccta aaacactgcc
    58981 gattttggac gcaaaaccag gaactgattt tactttacca aaaggacgaa cagtccaaaa
    59041 accattatcg aagaaaggat gaggaagaaa tgaagaaagg gtgtctaggt tgtcttcttt
    59101 tctttattct tccctttttt ctattgccat tctttttttc aggagaactt tctgagcatg
    59161 gaggagaagc tacaggtcta gctgtcgctt ttaatgggga atataccgaa ggattaccga
    59221 ttttttcaga gattaaagga cgtggtccaa tcacagatga acatgcgcaa gcagcagttg
    59281 gtgcagctgt aaagtatcag ttattaccga gtgtgattct ttctcaatta ggctatgaat
    59341 cagcttatgg acagtcacaa tctggaagaa acgatacgaa cttttttggg attacctggt
    59401 ttcctggttg tccctaccca caaggttctg cacgtggaat tggtggttct gaaggtggtt
    59461 tctatatgaa gtttccgaac ttaaaagctt gttatgacta ttatggcttt atggtggcga
    59521 gccaaagcaa ctttaatcaa tgtgtgggca ataaagatcc tggaagttgt ttattgattc
    59581 taggtcgtgg aggctatgcg gcagcaggta ttaccgaagg gagtccgtat tatcgaggag
    59641 caatgagtat cataacgtcc tataacttaa cggaatatga tacttttgcg atcaagcatt
    59701 ggaatagcct accaacaaaa aaaacttcgc ttattgcagg aaaaagtaaa ggcaatgcga
    59761 aggttttgga tcggatcatt ggacgatccg taaataatgg ggaatgttat ggtggtacgg
    59821 catggtatgt atctcaatta ggtggcccac agttaatggg ttctggacac atgtttgcga
    59881 tgttaatagg ggaagattat aactggacaa cctatggttg gcaagtaatc atgaacccaa
    59941 aaccaagtga tttacaagca ggagatgtgg tgaattggca agcaggtggt gcattgtctc
    60001 ctggaatcta tggtcacacc ggaattataa cagatgtttc atatggcgga caacatttct
    60061 ctagtgtgga acagaatgcc gagcaaggac ggattatggc tcggtatcaa cgcacgtaca
    60121 atcaaacaaa aattcgtagt ctggttcgta aggtgaaata agaaaggcag tgactagaaa
    60181 cgtgaaaaaa gggataattt tagtatttag ttggttatgt ttgataggtc ttactggttg
    60241 tcattggttt tcttctgaaa aacaaaaaac acaattgaga acgacagaag aaacaatcga
    60301 agcagtaaaa gaaacaagtg gaactcttca aagtactgaa agtaacagtc aaattggttc
    60361 attagaagac gagacagcgc aacaaatgca aatagatgaa atgacaaaaa atttcttaaa
    60421 agattttgct agaaaatgga gtaatttcac agatgtttat aaacgcaatc aagctgtgag
    60481 ggactatatg acagatcgtt gtattaaaga caatagtatt gatgtagacc cgcatgtaca
    60541 aatgaaaaca actgggaaac tttaccaggt gacacaagat atagagaatc cggatcaata
    60601 tttgttattt ggagaagaaa caatgaataa ggttactcaa tttgtattac ttcaattgaa
    60661 agtaggtcaa gaagctcaaa agattgatgc gatcaagatt tattatgtac ggagtgcgta
    60721 ttaaaataaa aaatgaacac tcatatttat tatacaccga agaaatagaa aaaaacagac
    60781 tgttttttta agaaaaacta tgtcattctt tacttgaaaa aagttgttat aggacagaaa
    60841 ggataaaaca aaaacggaaa aaatatgtct tatgaataac tataagaact attctatttt
    60901 ttaggagatg gatacgagat gaaaaaacta attggctata gtgtgatgtg tattggattt
    60961 gttggtgtgg gattgtttgt atcgactgaa tctgcttctg cggctgaatg gtataatcct
    61021 atctggtata atccgaacat tgaatgtcaa aaaggctatc cgtatggacc gacaaatctg
    61081 aaaaatggaa aatgtagagt aaattggaat ggcgttgtag atagtgtaat tactggttca
    61141 atggactctg ctctacatgg ctttacgggt cactagaagg aggaagaaaa tgtctgaaga
    61201 gaaaaaagaa atcgttgaat cattagtagc tttaaaagat tctctttcta agattgaata
    61261 tgttgatagg caagaaattc aaaaactaat tgatgatact attattgaaa tccaagatgc
    61321 gcgttgtgaa ggtataaaaa tttctgtagc tttatctaaa gtaatagaaa aaatgaaccg
    61381 ttcattagcg tttaatggat tgaagctaga tagacaaact agtctgatat gggatcattt
    61441 aaaagacttg tatgacaagt ctaaaagaag tgaacggact gctgtatcaa tcttaaaagg
    61501 cctttgggga atgaattcat aaacaagata tttaaaaagt aacttatttt ttatggagga
    61561 gaaattatga aaagaataat taaaatattt ggtgttttag gtgttttctt attaggttta
    61621 agtacttttg ttagtactgg aacaagtgtg tatgccacag aaaaagtgaa tacagttgat
    61681 ttagaaataa agaataaatt agtagatgaa ttaacttttt attttgatac agttggtttt
    61741 ttagacgaac atggtgtata ccatataaag gattttggtg ctattcgtga acgaatcagt
    61801 caagataacg aacaaggaag agcagcaaga gtcttttatg aacatattat tgttcctaga
    61861 atggagaaag ttgattggaa acgatatgct ggatgtgtag ccattaattc tcttcctgga
    61921 ggaggagtgg cttgggctat aggtacgcag ggagatttta ttgaagcatt aaaagctttt
    61981 aattttgaaa aagctgcgga tttattatta aaaattgcag aaaaacaatt aggaaaagct
    62041 gcagctaaag agttagctaa ggtaaatatt gtagcaggaa ttgcagcagc tgctgctagc
    62101 tgtgcattag agtaaaagtt tatgaaaagt ttagaacaag agcatatggc ttttaaacaa
    62161 gcaatgttta aagaaaatat ctatttaaac cataactata ttcgtgtttc taaggcatgt
    62221 tcaccagtat tgaatatgct tggaggtgga aatggattat atcatttact gtttgtcgat
    62281 gtttgttggt taattttttt a
//
LOCUS       DADVXE010000010        60304 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.010, whole genome shotgun sequence.
ACCESSION   DADVXE010000010 DADVXE010000000
VERSION     DADVXE010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 60304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60304
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.010"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..832)
                     /locus_tag="KB913_000655"
     CDS             complement(<1..832)
                     /locus_tag="KB913_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6819041.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     Y"
     gene            complement(1056..2996)
                     /gene="thrS"
                     /locus_tag="KB913_000656"
     CDS             complement(1056..2996)
                     /gene="thrS"
                     /locus_tag="KB913_000656"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBB6819042.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3333..3512)
                     /locus_tag="KB913_000657"
     CDS             complement(3333..3512)
                     /locus_tag="KB913_000657"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBB6819043.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3559..5382)
                     /gene="cadA"
                     /locus_tag="KB913_000658"
     CDS             complement(3559..5382)
                     /gene="cadA"
                     /locus_tag="KB913_000658"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBB6819044.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5660..7939
                     /locus_tag="KB913_000659"
     CDS             5660..7939
                     /locus_tag="KB913_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6819045.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8032..8679)
                     /locus_tag="KB913_000660"
     CDS             complement(8032..8679)
                     /locus_tag="KB913_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819046.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8858..9577)
                     /locus_tag="KB913_000661"
     CDS             complement(8858..9577)
                     /locus_tag="KB913_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6819047.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9708..10859)
                     /locus_tag="KB913_000662"
     CDS             complement(9708..10859)
                     /locus_tag="KB913_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBB6819048.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11076..11816)
                     /locus_tag="KB913_000663"
     CDS             complement(11076..11816)
                     /locus_tag="KB913_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6819049.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11820..12143)
                     /gene="rsfS"
                     /locus_tag="KB913_000664"
     CDS             complement(11820..12143)
                     /gene="rsfS"
                     /locus_tag="KB913_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBB6819050.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12200..12793)
                     /gene="yqeK"
                     /locus_tag="KB913_000665"
     CDS             complement(12200..12793)
                     /gene="yqeK"
                     /locus_tag="KB913_000665"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBB6819051.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12777..13427)
                     /locus_tag="KB913_000666"
     CDS             complement(12777..13427)
                     /locus_tag="KB913_000666"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBB6819052.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13437..13748)
                     /gene="yhbY"
                     /locus_tag="KB913_000667"
     CDS             complement(13437..13748)
                     /gene="yhbY"
                     /locus_tag="KB913_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBB6819053.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13764..14873)
                     /gene="yqeH"
                     /locus_tag="KB913_000668"
     CDS             complement(13764..14873)
                     /gene="yqeH"
                     /locus_tag="KB913_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBB6819054.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14870..15397)
                     /locus_tag="KB913_000669"
     CDS             complement(14870..15397)
                     /locus_tag="KB913_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBB6819055.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15577..16362)
                     /locus_tag="KB913_000670"
     CDS             complement(15577..16362)
                     /locus_tag="KB913_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBB6819056.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16355..17224)
                     /locus_tag="KB913_000671"
     CDS             complement(16355..17224)
                     /locus_tag="KB913_000671"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBB6819057.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17225..18604)
                     /locus_tag="KB913_000672"
     CDS             complement(17225..18604)
                     /locus_tag="KB913_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBB6819058.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18612..19031)
                     /gene="fabZ"
                     /locus_tag="KB913_000673"
     CDS             complement(18612..19031)
                     /gene="fabZ"
                     /locus_tag="KB913_000673"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBB6819059.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19056..19532)
                     /gene="accB"
                     /locus_tag="KB913_000674"
     CDS             complement(19056..19532)
                     /gene="accB"
                     /locus_tag="KB913_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBB6819060.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19535..20770)
                     /gene="fabF"
                     /locus_tag="KB913_000675"
     CDS             complement(19535..20770)
                     /gene="fabF"
                     /locus_tag="KB913_000675"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBB6819061.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20789..21526)
                     /gene="fabG"
                     /locus_tag="KB913_000676"
     CDS             complement(20789..21526)
                     /gene="fabG"
                     /locus_tag="KB913_000676"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBB6819062.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21538..22455)
                     /gene="fabD"
                     /locus_tag="KB913_000677"
     CDS             complement(21538..22455)
                     /gene="fabD"
                     /locus_tag="KB913_000677"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBB6819063.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22562..22786)
                     /locus_tag="KB913_000678"
     CDS             complement(22562..22786)
                     /locus_tag="KB913_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBB6819064.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22839..23801)
                     /locus_tag="KB913_000679"
     CDS             complement(22839..23801)
                     /locus_tag="KB913_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBB6819065.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23811..24251)
                     /locus_tag="KB913_000680"
     CDS             complement(23811..24251)
                     /locus_tag="KB913_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6819066.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24557..25522
                     /locus_tag="KB913_000681"
     CDS             24557..25522
                     /locus_tag="KB913_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBB6819067.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25579..25809)
                     /locus_tag="KB913_000682"
     CDS             complement(25579..25809)
                     /locus_tag="KB913_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBB6819068.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(25895..26782)
                     /locus_tag="KB913_000683"
     CDS             complement(25895..26782)
                     /locus_tag="KB913_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBB6819069.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(26871..28094)
                     /locus_tag="KB913_000684"
     CDS             complement(26871..28094)
                     /locus_tag="KB913_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6819070.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28111..29157)
                     /locus_tag="KB913_000685"
     CDS             complement(28111..29157)
                     /locus_tag="KB913_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6819071.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(29321..31048)
                     /gene="ptsP"
                     /locus_tag="KB913_000686"
     CDS             complement(29321..31048)
                     /gene="ptsP"
                     /locus_tag="KB913_000686"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBB6819072.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(31048..31314)
                     /locus_tag="KB913_000687"
     CDS             complement(31048..31314)
                     /locus_tag="KB913_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBB6819073.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            31793..34027
                     /locus_tag="KB913_000688"
     CDS             31793..34027
                     /locus_tag="KB913_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6819074.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34175..34495
                     /locus_tag="KB913_000689"
     CDS             34175..34495
                     /locus_tag="KB913_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBB6819075.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(34700..34924)
                     /locus_tag="KB913_000690"
     CDS             complement(34700..34924)
                     /locus_tag="KB913_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBB6819076.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(35122..36702)
                     /locus_tag="KB913_000691"
     CDS             complement(35122..36702)
                     /locus_tag="KB913_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBB6819077.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(37103..38479)
                     /locus_tag="KB913_000692"
     CDS             complement(37103..38479)
                     /locus_tag="KB913_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBB6819078.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(38607..39725)
                     /locus_tag="KB913_000693"
     CDS             complement(38607..39725)
                     /locus_tag="KB913_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6819079.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            39867..40301
                     /locus_tag="KB913_000694"
     CDS             39867..40301
                     /locus_tag="KB913_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6819080.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(40379..40912)
                     /locus_tag="KB913_000695"
     CDS             complement(40379..40912)
                     /locus_tag="KB913_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBB6819081.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(41006..42184)
                     /gene="mutY"
                     /locus_tag="KB913_000696"
     CDS             complement(41006..42184)
                     /gene="mutY"
                     /locus_tag="KB913_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBB6819082.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(42177..42974)
                     /gene="recX"
                     /locus_tag="KB913_000697"
     CDS             complement(42177..42974)
                     /gene="recX"
                     /locus_tag="KB913_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBB6819083.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            43081..44463
                     /gene="rlmD"
                     /locus_tag="KB913_000698"
     CDS             43081..44463
                     /gene="rlmD"
                     /locus_tag="KB913_000698"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBB6819084.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(44637..45215)
                     /locus_tag="KB913_000699"
     CDS             complement(44637..45215)
                     /locus_tag="KB913_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBB6819085.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            45537..46007
                     /locus_tag="KB913_000700"
     CDS             45537..46007
                     /locus_tag="KB913_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBB6819086.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(46115..47341)
                     /locus_tag="KB913_000701"
     CDS             complement(46115..47341)
                     /locus_tag="KB913_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6819087.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(48095..48295)
                     /locus_tag="KB913_000702"
     CDS             complement(48095..48295)
                     /locus_tag="KB913_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6819088.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(48429..49037)
                     /locus_tag="KB913_000703"
     CDS             complement(48429..49037)
                     /locus_tag="KB913_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBB6819089.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(49122..49592)
                     /locus_tag="KB913_000704"
     CDS             complement(49122..49592)
                     /locus_tag="KB913_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBB6819090.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(49640..50554)
                     /locus_tag="KB913_000705"
     CDS             complement(49640..50554)
                     /locus_tag="KB913_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6819091.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            50700..51503
                     /locus_tag="KB913_000706"
     CDS             50700..51503
                     /locus_tag="KB913_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBB6819092.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            51681..52628
                     /locus_tag="KB913_000707"
     CDS             51681..52628
                     /locus_tag="KB913_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBB6819093.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(52696..52989)
                     /locus_tag="KB913_000708"
     CDS             complement(52696..52989)
                     /locus_tag="KB913_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBB6819094.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYNPNLEEPTYHFKKQ"
     gene            complement(53017..53682)
                     /locus_tag="KB913_000709"
     CDS             complement(53017..53682)
                     /locus_tag="KB913_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBB6819095.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(53822..54454)
                     /locus_tag="KB913_000710"
     CDS             complement(53822..54454)
                     /locus_tag="KB913_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6819096.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(54461..55528)
                     /locus_tag="KB913_000711"
     CDS             complement(54461..55528)
                     /locus_tag="KB913_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6819097.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(55525..56256)
                     /locus_tag="KB913_000712"
     CDS             complement(55525..56256)
                     /locus_tag="KB913_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBB6819098.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(56425..56904)
                     /gene="greA"
                     /locus_tag="KB913_000713"
     CDS             complement(56425..56904)
                     /gene="greA"
                     /locus_tag="KB913_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBB6819099.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(57040..58215)
                     /gene="mltG"
                     /locus_tag="KB913_000714"
     CDS             complement(57040..58215)
                     /gene="mltG"
                     /locus_tag="KB913_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBB6819100.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            58419..59588
                     /locus_tag="KB913_000715"
     CDS             58419..59588
                     /locus_tag="KB913_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBB6819101.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(59855..>60304)
                     /locus_tag="KB913_000716"
     CDS             complement(59855..>60304)
                     /locus_tag="KB913_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819102.1"
                     /translation="MNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTED
                     GQVIYSSFSPNKDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTV
                     KSESGINKVTIRYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT        17508 a        12642 c        10163 g        19991 t
ORIGIN      
        1 aatattcttg gattgcttct cgtgtttttt tcactttttc gctaagcttt tcgtttttag
       61 ccatatagaa ataaaaaatg atatcgatcg tagcaaattg ggccaaaagt gaattagttg
      121 ccgcacttcg attcgtgatt tcttttggtc tagatgtttg tacgagtaca tcggctatct
      181 tgctaagcgg gttatttcca aattgcgtca acgcaatgat ttcgatattc atgcttttcg
      241 ccagctcggc taatgcgact acatctgcac ttctacctga gtttgaaaca agccaaagca
      301 ctttcttttt ctcattgctg acaagttgcg ggagcaagac gtggatatct ttttcaaaaa
      361 tgattggctt accgacacga gaccattttt gcagaatatc ttctactact aaagaagagg
      421 cgccaacccc atataaaaaa acagtctctg ccgattccaa acactctacg actttttgga
      481 tcgtttcttc ttctagaata tctactgttt cttttatcgc tacttgtgca ttgttaccaa
      541 gtttgttttt gatagagtaa aaggactcat ttgcttctat atcactaaaa ccttcatcga
      601 ttccagtctg tagttctgtt gaaatcgtga ttttgaagtc cgtcagactt tgaaaaccga
      661 tttttttgga aaaacgtaca actgtcggcg cactcaaccc ggaagcttct gctaattcat
      721 tagctgtcat tgtagggacc ttctcaatat taccgataat gtagttggcc aacttttttt
      781 ctgctgaaga ataatcttcc atcatacttt caatacgact aattacgctc ataagttcct
      841 ccaccctttt aatgatagtc tatgtaagta taccatatca gacccttatt cacggtcgta
      901 tactggataa aaaacaaaaa aacaatccgc ccaacagaat atcttatccc atcaatccca
      961 cagattctat tgagcatctg tgtctttgag gaatacctgt tatctattgt tcggattgct
     1021 ttctatctac tactttttta caggaaattt acctattagt tttctctgct gtaatttttg
     1081 acttctgctt ccatagcatc aataaagata ttcaaatctt ctacagctgt ttctttactt
     1141 ccataacgac gtacgttcac tgttgcatct tccaattcct tgtctccaac aactaattgg
     1201 taagggatct tttgtgtttg agaggcacgt atcttatagc ccattttttc attacgatca
     1261 tcaacttcta cacgcaaccc cttcatttgc aaacgttctt tgatttcata agcataatcg
     1321 ccatgtgcat caacagaaac agggatgatt gttgcttgta taggtgccaa ccatgttgga
     1381 aaagcgcctt tgtatacttc tgttaaataa gcgacaaaac gttccattgt agaaacaatt
     1441 ccgcggtgga taactactgg acgatgcgta ttttccccgt cttctccaac atatgtcaaa
     1501 tcaaagcgct ctggcaataa gaagtctaat tgtatagttg ataatgtttc ttctgtacca
     1561 agagctgttt tgacttgaac atctagtttt ggtccgtaaa aggctgcctc gccttctgct
     1621 tcaaagtaat ctagttctaa ttcatccata gcggctttca gcattgcttg ggctttttcc
     1681 cacattgcgt catcatcaaa atatttatct gtattgtttg gatcgcgata gctcaagcgg
     1741 aaacgataat ctgtaatatt gaagtcagca tatactgcca ccatcaattc aagcgtacgt
     1801 ttaaattcat ctttgatttg atcaggacga acaaatgtat gaccatcatt caacgtcatt
     1861 tctcgtacac gttgtaaacc tgacaaagca cctgattttt catagcgatg catcattcct
     1921 aattcagcga tacgaattgg taattcacga taagaatgga tcgtgttttt gtagaccatc
     1981 atgtgatgag ggcagttcat tgggcgaaga acaagcattt cgccatctcc catatccatt
     2041 ggcgggaaca tgtcttcttg ataatgatcc cagtgtccag atgttttgta caactcaaca
     2101 tctcccatta ttggtgtata tacatgttgg taacctagac taacttcttt gtctacgata
     2161 taacgttcga tcgtgcgtcg gattgttgcc ccttttggaa gccagaatgg caaaccagaa
     2221 cctacttctg gggaaaccat gaacaagtca agttcttttc ctagtttacg atggtctctt
     2281 tcttttgctt cttcacggag acggatatat tctttcaaag ctttcttgtc aaaaaaggct
     2341 gtcccgtata cacgttgcat catttgattg tttgagtttc cacgccaata agcacctgcc
     2401 actgataata atttaaatac ttgtatacgg ccagtggatg gaacatgtgg tccacgacac
     2461 aaatcgatga attcgccttg ttgataagca gtaatcactt cttcttctgg caattcacta
     2521 atcagttcta ctttgtacgg atcacttgca aaaatttcta atgcttcctg ttttgaaaga
     2581 acacggcgtt cgatcggcag attttctttg acgattttca tcatttctgc ttcgattgcc
     2641 ggcaaatctt ctgcagttac ttggttttgt ccattatctg tatcgtagta aaaccctgaa
     2701 tcgatagctg gtccaacgcc aaagtggata tttggataga ggcgacgcat ggcttgggcc
     2761 atcaaatgag ctgctgaatg acggactaag ccaagtgcat cttcatggtc tggtgtgatg
     2821 atctcaatac ttgcatcttc ctcgattgga cgagtcaaat caacgagttt tccgttcact
     2881 ttaccagcta aagctttttt tgctaagctt tttgaaatgc tttcagcaat tgccaatgtt
     2941 gttgttccag actcaaattc tttgactgca ccatctggaa aagtaatttt tatcataata
     3001 gtttcctcct tgaaatgttt tgattgatca gatcatcaag ctgaaaaaca aaaaaatcct
     3061 agcatctctt gaaaagagat actaggacga aaagttcgtg gttccaccta atgttcaaac
     3121 gcaaatgcgt tcctcaagcg ttgtaacggt ccgaccgccc ttgcttcaac aagggtttcg
     3181 aaagtggtca tcctttggtt ttctcctgga aaagtttcag cctagctttt cctctcttat
     3241 cgaagactct caaattcagt tggctttctc atcaatcaat tatgtgttta tttaaccact
     3301 aataaataga aaaatcaagt gggaaactaa acttattttt tccattcccc atttacaccg
     3361 tatgttcctt ttttcatctc attgatgatg acatggatgt gttcttttgg tgcctgcgtg
     3421 tttttatgaa cagcttccgt gatatctttc atcatatttt ctaattgttc cggactgcga
     3481 ccttctacta attcgacatg tacgaatggc ataatgctct ctcctctttc tgatcgttct
     3541 tttttcaact cgattctatc atactatgtt tgtcttgggt actgaatcag gaaaaatggc
     3601 tggatctttt tttgctctca aggcactcaa aatagagacc gtatccacga cttcttgcaa
     3661 aacagctccg aataatgcgg ggattagtcc cgtacttgca attaacatca aaaaaataca
     3721 aataaagatg ccaatcagta cagactgttt cgctattctc atcgtatctc ttgaaatcac
     3781 tactgctttt gctacacgca agagatcatc tttcaagatg accgcatctg cactttcact
     3841 agcagctgta gaaccatgag cccccattgc aataccgata tctgcagcag caagtgctgg
     3901 tgcgtcattc acgccgtctc ctaccatcgc aacaggtctt tgatctttag ggatactttc
     3961 taaaatggtc agtttatctt gaggcaagct acgggcatgt acagaatcta attggacttt
     4021 ttctgcaatc gtttgagcaa tggcagatcc atccccggtg atcatcatca aatttttcac
     4081 atcaagtttt cttagctcct tgattgtctt tgctgcttct gggcgaatct gatccgaaaa
     4141 taggatcgtt cctgcaaaag atcgatcaat tgttacatag attgctgtat tggacgtttc
     4201 tatttcttca gctgaaacaa aagaggcacg tccaatcttt acttcatgat tattgactac
     4261 tgcttggatt ccttgaccgg tcacttcttt cagttgacta acaggataca gttggctgtt
     4321 tttcacgttg ttcactaacg aacgagctaa gatatggcta gattcctgtt ctgcactagc
     4381 tgcatacaga agtagctctt ctttttttat tccattgact ggctgaatcg cctctacttc
     4441 caatatccct ttggtaagcg ttcctgtttt atcaaaagca atcgtttttg tacgtgcgag
     4501 cttttcaatc gttgttccag tttttacaac gatcccgttt ttacttgaac ggctcattcc
     4561 tgcaactaaa gcaatgggcg cagctagaat cagtggacaa ggtgatgcca ctaccagtac
     4621 ctcagcaaat cgtaaagggt cttttgagaa ccaccaagaa ataccaccga tcaaataagc
     4681 aatcaacgtg aaagggactg cataacgatc agctaaacgg acaaatcggg caggcttttc
     4741 ttttgattct tcgactagtt taataatcat ttgatactgg ctgtctgcgg cacgtttttc
     4801 agcgatcatt tggatcgatc cgtctccatt taaagaccct gacataatct gatctccagg
     4861 tttcttggtt tccgggcggg actcacctgt caaagaagat tcatcgaccg aagattctcc
     4921 tttggtcact cgaccatctg cgggtacaag ttcgccaggc ttgactagta actggtcatc
     4981 aatatttatt tcatcgatta ctatatcctg caattttcct tctttgaatc gatgggcaat
     5041 tcttggggtg ttatctaaca aagactgcag ttctttaccc gctcgtttat tcgcgtaatc
     5101 ctctagacta tctccgcccg taagcatgat caatatcatc aaactagccc agtattcttt
     5161 gacggctaat gttgcaagga ttgcggtaat cgctaataca tctacgccat atcttcctga
     5221 acgtaacgtc ttgatcattt ccaaaaacat caagaaggcg agaatccctc cagtaaatgc
     5281 gacaatcgca aatgcaaggg ccggctggtg aaaaacaaat tcacttaata aagctatccc
     5341 accaataagc aaagtaagta aaaatttttt gaaatgtgtc attgtttttt ctcctctttt
     5401 atgtgactta gagaggttag taataaattt ccagctgcct ctttcatctt aagcatagtc
     5461 cttgactagc actttttaaa acaataggcc ttaattgaaa acaactatca ctatcagcgt
     5521 ttccaaaatt catcagttct acaaacaaaa atattcagca aggattactt tttcgattca
     5581 tcagttaaaa agtacctttt ttcgaaaaac tatgctatac ttttaattcg ttatttacgg
     5641 cggaaggagc aaacatgcga tgaatgagaa acaactagaa caaacgcacg tggatgaaac
     5701 gatcgaacta atccagatcg aacaaaatat gctggataca aaacaacaag aattgactca
     5761 ggaaatgaat cattcgacaa aagacacagc taatcacaag attcgagctg gttccaatga
     5821 agctttttat gaatctgctg ttgaatatcg ccaacatgag caggaattgc ttttgaaata
     5881 ccatactctt gaagcacagc aaaaacgcct gcaaacgttg tctgtcatga aagatagtcc
     5941 ttattttgcc cgtatcgact ttaaagaaga ccgtgaaaca gaaacattat atctaggtat
     6001 cgcttcttta agagatctgg cagaagaaac aatcgttatt gactggcgcg caccaattgc
     6061 caatctttat tatgaaggtg agattggtcc cgcattttat gaaactgaaa cagatagaat
     6121 agatgtcgat ctgcagttga aacgacaatt taaaatccaa gaaggacgta ttttatctat
     6181 ggtagatacg tcggaagtaa tcaatgatga ctttttgcta gagatattgg atgaatcatc
     6241 aagcaaccat atgaaaaaca tcgtctctac gatacaaaaa gcacaaaatg caatcattcg
     6301 ggacacaaca agtaaagtaa tgctgattga aggaatcgcc ggaagtggaa agacatccgc
     6361 tttgcttcaa cgtattgctt ttctgttgta tcataatcgc aagtggctcg aggctgaaaa
     6421 cgttcttcta ttttcaccca accatttgtt ttctgattac atctcgactg tattgccttc
     6481 attaggtgaa agcggcgtgc ctacacagac attcaaaaat tatttggtgc agctgctgcc
     6541 agagttttct ttactagatg aacagcaaca agaaagtggt tttttgctag gggaaaaaga
     6601 tccgatacaa gtgatgaaaa gcggattgac cttagtcgat cagattgatc gctatatcca
     6661 aggcatcaca aactacggtc ccttgttccg tgatatgaaa ataaatggcc gtacgatcct
     6721 atcaaaggaa tcgattcgcc aatggtataa agaaacaaat gaacaattac ctttacatca
     6781 tagactttct ctattacaaa cgaagctcct gaaaaaatta ggcggtctgc aaaaagacga
     6841 aacacgtcag caatgggtca aagatctggc ggaagaacag ctccaagaac tatacgcaac
     6901 agatccaaat cttgaatata cagaacaaaa ggagcgttca ttacgtaaaa aactggccaa
     6961 ccaaatcgta cgtaaaagat tccgtcgaat ccatcgaggg atcatgaatt atcaatttgt
     7021 caatataacg aaacaatatc tccactttct acaaactgtg ccactttctc ttctaacacg
     7081 acataaaatc agcgagacca ggtggcagga acatttgaca actgttcgta cacacttgcg
     7141 tcaaagagaa ttgcgtcaag aggatgctgt actattcttt ttactgatgc gccgaacata
     7201 tccagtgacg gttacacaca aagctcgcta tatctttatt gatgaaatgc aggatttcgc
     7261 accatcacaa gtggcattgc tgcaagcctt gttcccaaaa gcaaatttga ctttctgtgg
     7321 agatctaaat caaaatgtct ttggaaatga aacgatcgtt ggatcattgg aagacctttt
     7381 cgtggaccgt gaagtcactc gtttccaatt aacgacaagc tatcgctcca caaaagaaat
     7441 cactgatttt gctaatcatt ttattgtgaa agaacatcaa gtagaaacaa cagcaagaaa
     7501 aggagacctt cctttgctca tccaaggaac aacagatgat atcaaattga attggttagc
     7561 agataccatt cgaacgactc agggaaaagc ccggtattgg cgtacagcaa tcatagctaa
     7621 aacacaagaa gaatgcgaag ctctttatgc tcaactgcca gacgagttga aacaacaagt
     7681 ccagctgatt ttaaatgaga gtgactttat gaagcgttcc attattttac ttccagcctt
     7741 tttagcaaaa ggtctggagt ttgaccgagt tttcttgtgg gatgtagatg cagaacattt
     7801 ttcttctcag caagacaaat tgatccttta caccatgtgt acacgtgcga tgcatgaatt
     7861 gacccttttt acctccaata atgaaagtcc tttgttaaac aatatggata tttcatctta
     7921 tgagaaaaaa gtactgtaag taaaaagaca actgctatca ttaatgttag cagttgtctt
     7981 tttatttaca ataataattg cagaaaaagt aattcaatca tttaaggtca tttattctat
     8041 atataaatcc aaatctgttt caggatattt taatttgaca agcgaaataa tcattttcag
     8101 ttcttccatg ttttctggat attctgggtc aaataccttg ctatgacggc caatcccgcc
     8161 attgtcgatc aatcggtaaa ttcgattcca ttcaatgaat tggtcaattg attggaaatt
     8221 gctgattgga tagccgccac aatccaaaat ctctgataca cgaaatgcta ggtatgcact
     8281 atcgatcact ttattttttt tcgtgtctat cttctcattt ctttcgataa gaattttttc
     8341 aggacgatgt ttcaagctcc actctaatag tagaaagaaa gcctccatcc gatactcttc
     8401 ttcaaataac cgaaaggctg aatcagaacg acgaaaaagc agcggaatca gataattttg
     8461 tctataaatc agcattggtg cgcggtccac catacactct aaataacggt tcagataccc
     8521 tgtaccgaca tagtttccta atcgatagcc ttcaacgccg aatcttgcgt atttttgcgc
     8581 taattttgaa caatcagtta cgttcacagc taactcttct actttgcggt aaccgcttaa
     8641 gatacgttca aaaggttcta aagtgatttt tgcttccata ttcttccccg tccatcttcc
     8701 acatacttca tatcatttca catgatactt atgctctcat cataccacag gttgaattag
     8761 aaaagaaaat aaatcacaca aaaaagcaag acaatctgtt agtgagattg tcttgctttt
     8821 cgaaaaagac tgaatacttt tcgttaaaac tggttgctta gtcttctaat gccacattat
     8881 ggaacacatg ctgtacatct tctagatctt ccagtgcatc aatcattttt tcaaatgttt
     8941 cttgatcttc tggagatagt gttacctcgt tttgagggat catttggatc tcagcgattg
     9001 aaaaatcagt gattcctttt tcttttaatg cttcttgtat actatggaaa tccgctactt
     9061 caccgtaaac gatgatttgt ccttcttctt ccattacatc gcgaacatcg atgtcttttt
     9121 ccattaggta ttcaaggatc tcgtcagcgt cttctcctgc aaaagcaaag attgctgtat
     9181 tgtcaaacat gtaagaaacc gctccggaaa cacccatgtt cccgccattt ttcccaaatg
     9241 ctgcccgtac gtctgctgct gttcgattca cattgttcgt caatgtatca acaatcacca
     9301 ttgagccgct tggtccaaat ccttcatagc gcaattcaga gtatgtttca tctcctgcac
     9361 cttttgcttt ttcgattgct cggtcaataa tatgttttgg tacattataa gttttagcgc
     9421 gatcaatgac gaaacgtagt ttttggtttg catgcggatc aggatcacct gattttgctg
     9481 ccgcgtagat ttcaatccca aattttgcat aaatccggct attattagca tctttagcag
     9541 ttttctttgc tacgatattt gcccatttac gtcccatatt ttcacttcgc tttctgattt
     9601 gatagtttca taacgcaaaa acgtcctgtt ccattatact tgtgaatcac gattctgtga
     9661 agcttttttt ctttcttcct tcattcttct catttttagt caattatcta tactcggatt
     9721 gggatttgcc cgaaattctg ttccggaata ttgcctccca attgatagat ttgatcactt
     9781 ctaactaaca gttccgcttc ttgtgcctct ttttttccga ttcgggaata aatagaaatc
     9841 tctttttttt cttttaagaa tcttcttcca gcatcggtaa atccaagtag tcgaagataa
     9901 tttttatttt gttggacagg aatctcttgc tttttgatat tcagcaagac ataacaagat
     9961 aatcgttgga tccgtgtcca tgtatatctt tttgttttta cctttgacac aaaatcctca
    10021 aaactatcag cagttgcagc tgctgttttc atgcgcgatt ctattccttc ggtcatctga
    10081 tagatatctg tcagttccag caaagtagaa gataacaacc gataacgcaa atacggccaa
    10141 taagattccc aagtctgcag cgaacaagtt gaaagatctt cttctgtctg aggcggcaca
    10201 agtccagcta ttctttttcc ttcttctaac gcatggcgaa tggctgttgc actggctatc
    10261 ctctgatctg tgatgatttt ttcatgatag cctgcacttt tacgtcggat cggatgtaat
    10321 tccatagggt ggacatactt ggcattttcc tttgcataac ttaatcccaa gatatgattt
    10381 ggcgaagaaa aatcaagcgt aatatcggga tacagactgc gaaaaacctc agtcattttt
    10441 tgcggataac tatacgtttg atcagacagt tcttgaaatg cctcttctat cctatcttga
    10501 ttctcttgga caaagcgtcc gaaactgctg taatcaaacg aagtctcttc ttctgttcca
    10561 aaacacaaac tgtcacagtc cagtgtttgc aagattttta ctgcaccttt agcaaaatag
    10621 tcagctgact gaaccgccca ttcgacggga agctccacta ctaaatccac accattttgt
    10681 aaagcttcat tcgcgcgatg ccatttatcg atgatagccg gttcgcctct ttgcaaaaaa
    10741 ttcccgctca ttacagcaat gacgacctct gctcctgtta tttttcgtgc catttccaca
    10801 tgatagcgat gtccattgtg aaaaggattg tactctacga taatcccgca gcttttcatg
    10861 cgcatcctcc ttcatagtta tcgataaaaa agaaatagag acaagtaaaa aaaggcaaaa
    10921 atcggaaaaa atacccgaac tatataaact attctcgcaa acacaatact tctgcgacga
    10981 aaagctgcac tgcaagagca atgcctatat cgttcggata tataatttat gttgaagatt
    11041 tattcttttc ttgttaactc gagcaggcaa aaccgctagt ctttgtatgc tacaaagaac
    11101 cagcgctttg atttctctga tgctgcttcg tctgtaaaat cagaaaatgc ttcgactttc
    11161 gaaaagccgc tgttttccag cattcttaaa taactttcca atggataggt acgctcttga
    11221 tgtagttcat cttcacgaat aaatcgacca gacccttctt gttcttcaac gaaaaaggta
    11281 agaaaatgtt cgatgctgtg tttctcgctt cctggataac tatcccacaa aaaagcaaaa
    11341 ttatcccctt gataatgata gctatattct ggaaaaacct catctacttg ataggtggag
    11401 tgtacgtcaa ataaaaatcg gccattttct tctaacgctt gatagacttc atcaaacact
    11461 tgctgtacct cttgtctatt tttcatatag cacagcgaat cagaaaaaca ggtaattgcc
    11521 tgatattgtc cgatttctga taaatcgagc atattgcctt ccacaaattg gatcgatgcg
    11581 tcttcttcat atgctcgctg gctggcaatc atcaacatct cttctgaaag gtctaaccct
    11641 gtcactttat atccatcttt tgcaaaggca accgctaatg ctccagtacc gcatgccagt
    11701 tccaaaatat tttttgtgtc ttcttgtaaa tgacgtttcg aaaaagctaa ccattgctga
    11761 taaagtgttt cgtccatcac ttcatcgtaa atgaaagcaa atgtttcata agccatatgt
    11821 taatccaacc attcactaag atcgactagc ggagcatctg accatagttt ttccagatta
    11881 tagaaatttc gttctggcgc atggaaaaca tgtacgatca catctccaag atcgatcaat
    11941 acccattttc cgccttcttt tccttcaata cgttttactt catatttgtt ttcttcttct
    12001 ttatcaatga tttcttctgt aattgcgttg atttgacgtt cgctatttgc tgaacagatc
    12061 atgaaataat ctgccaacaa ggaaacattt cgaacgtcta aagcgataat gtcttctgcc
    12121 cgttttgaat ctgctgcttc aatcgcaatt tttaattgtt ctttactatc tatgatgatt
    12181 tcctcctaat atgagcagct tatttttttg ctacccagta attatatgtt tcgattgttt
    12241 ttggataaat ctgttgttct tgcgcaagca aatgggccaa tgtatgtttt gtttcaaatg
    12301 ctacagcttc gtctagatca gcccatgcaa tggctcgtgc atcttgtacc ccaggaaaat
    12361 ctcgacctgg ttcaatatag tctgctacat aaatgatttt gtcaaggaga ctcatcttag
    12421 cagccccagt cgtatgcacc cggattgcat gaagaatctc tgcatcggtg attcctaatt
    12481 cccgctctac aaacgaagcg ccaacaagac catgccagat tgcattatta taattcaata
    12541 actccggatc aaaaccgtct cttacgatta ccattttgaa ctcctcatct ggtcgttctt
    12601 ttgcataatc atgtgtcaat gcagcaatac tagctttttc aggagaagca ccgtattttt
    12661 tggcaagagc cacggctgtt tcttctactc caagcacatg cttgaagcgt tgttcgctca
    12721 ttctcatctg tattttttgc atcaggtttt ctctagaata agcagtatat tcattactat
    12781 agtccatatt catacaaccc ttcattttga atataatcaa ttactttatc tggaacaagg
    12841 tagcggatag aacagccttc tttgatcttt tgacgtattt tcgtggaact gatgtcgatc
    12901 tcaggtacat ctacccaaat tacaggatat ggagtatccg ttgtgtatcc tggtcgacgt
    12961 atacccacaa agttgaccat agaagtcagc tcatcgattt tataccattt tggcaaatat
    13021 tctaccatat ccccaccgat aataaagtaa taatctgtat ccggattgtt ttgcgtcaat
    13081 tccttcatag tatcataggt gtaacttttc ccaccacgag ctaattcaat cgtttcaatc
    13141 tgcaaaaaag gattgtcttc caccgctaat tccaacatgt tgagtcgatg ttttgcatca
    13201 atcgtctgtt tctcatcaac atgaggtggc tgataagaag gcatcaaaaa tacgcggtca
    13261 agacctaaat tccggccagc ttgttcagcc atcactaaat gtgcaaggtg aacgggattg
    13321 aatgttccgc ccaagatccc tacttgcttt ttcttctcta agaattgagg catttcttca
    13381 ggaaataatt gtgaacgaac aaatgtctta gcttgcgtat tcatcatggt cactccttat
    13441 attgctttta cttcttttga tagcctttga tacttttctt ttgtggaagg tttgtataat
    13501 acaataacac gtccaatgat ttggacgatt tcgcaatcta tttctttttc taatacttga
    13561 gctgcttctt ctgcaatctc atctgtattt tgaagtaacg atactttgat cagttctctt
    13621 ttttctaaag cttcttcaat ttgaacgatc attgctgaat tgatcccacc ttttccgatt
    13681 tgaaaaatcg gctgaagatg atgcgctttg ctacgtaaaa aacgcttttg ttttcctctt
    13741 aaactcataa ttttccttct tccttaaatc aatgctttgc gtttcaatac atctacaccc
    13801 tttggcgccc agcccgcaat tactactggc gctgttacag tgatccagcc tagaccggca
    13861 aaaacgatgt ctgttttttc tttcacagaa aactcaaaac gaacaagctc cggaaatgcc
    13921 tcgacttcat caggacgagg aggctgtaat aatccaccta catgtttttg ataaaattcg
    13981 tctgcttttt ccagtttcgt tcgatgaata tttacatcat ttgacacata agcaataaat
    14041 gaagcacgat tgccgctgat aaaatcaaat cttgcaagtc cgcccaagaa aagtgtttgc
    14101 ccttcattca gctgataaac tttaggtttg atttctttta acggtgcaat gatccgcaaa
    14161 tcttttttac ctaagtagtg cgccatttga tggcgatgga taattcccgg tgtatcaatc
    14221 aaaaaatgcc cgtcatctaa aggaatctcg attttatcca aggtcgttcc tggaaactgc
    14281 gaagttgtga ttacatcttg tactcccgct gtatttttga tgatttgatt gataagcgtc
    14341 gattttccga catttgttac tccgacgata tagacatccc gtccatcgcg gtattcttcg
    14401 attttttcta atagttccgt catctcatga gatttcttag cactagttaa taatacatct
    14461 actggacgaa ttcctgcttc gtaagcacgt tccttcatcc attgtgttaa tttagttttt
    14521 ttcaatgatt taggtaatat atccactttg ttcccaacta aaagtactgg attgtcaccg
    14581 acaaaacggt gtagtcctgg gattagtgaa ccattgaagt caaaaatatc caccacattg
    14641 acgatcaatg catctttttg ccctaattca ttcagtaagc gcaaaaagtc gtcatccgtc
    14701 aatgagacat cttgggtctc attataatgg cgtaatctga aacaacgctg acaatagact
    14761 tccccggaag ctaaaccttt ttccaaagcc gtttgcggcg tgtatcctaa ttcaccgggt
    14821 ttgtttgttt gtataacggc accacagccg atacattgta attcttctgt cattcgattc
    14881 cacctcgcca gcccatatca gggtgttttg ctaatagata ggccataatt cttttttccc
    14941 aaaaacgatt aaattgtgtc ttccaactat ctgttgcgat aatgggtttt acaaggatgc
    15001 tacgtatccc tgcacgattg gctccacgta tatcagtcat aatctgatcg cctaccatta
    15061 ctatctcatc atctgctaaa tccaattgtt tctttgctat gttgatccct cttgctaaag
    15121 gtttcattgc tcgtgcaaca tacaaaagat caaatttttc aatcgctcgc gcgacacgtt
    15181 ttgaattatt gtttgaaaca acaacaacag ggattcctgc atttttcatt tctaaaatcc
    15241 aagtaagcaa ctcttctgtt ccatctggat tattccatgc aatcaacgta ttgtctaaat
    15301 cggtcaatac tgctttgatg cctagattct ttaattgggc aggtgtaatc tgatagatgg
    15361 cttctaccat ccatgttggt ttgtaatttg aaaacatgct gtctcctcat ctgcaaaaaa
    15421 tgaaggagca cataaagtac tcctcaaccc cgtattatac tgcatatcag caaaaaaaac
    15481 tacctctata ctcgttcgtc tttcagaaaa agcatttctt tacaaaatga ccaaaaataa
    15541 agattgatca cagaaaaatt tagaaacaaa aaacaactaa tattggcgga acctcttgta
    15601 tcgtttttcc agtaatttat gctgatctaa tcgaacaagt tccgtcaatc tttcaatcaa
    15661 cgcttttttc ataatgtgtg cgactttata tcgtggcaac tgctcgccgt tgaacgtttc
    15721 aggaataact cgatcaacga ttcctaactc gcgtagttct ggcgcagtaa ttttcatcaa
    15781 ctcagctgct tctgcggcgc gactaccgtc tttccacaaa atcgacgcaa atccttctgg
    15841 agaaagcaca gcataaatcg tttcttccag catccagact tcatccgcta aacctagagc
    15901 aagggcaccg ccacttccac cttcaccaat gatgatggcg atgatcggta cctttaaatc
    15961 agacatttcg agcagatttc tggcaatagc ctctccttcg ccgcgctctt ctgctcctac
    16021 accgcaatat gcacctgctg tattgatcaa ggtaatcacc ggtctattga acttttccgc
    16081 ttgtttcatc agtcgtaaag cttttcgata gccttcagga tggggagaac caaaatttct
    16141 gcggatattt tcctgcagat cccgtccttt ttgaataccg atcactgtta ccggtttgcc
    16201 atctaatcga gcgattccac caacaatcgc ttcgtcatct gcaaataaac gatcaccatg
    16261 gcattcctcg aaagaatcga agatctcttc aaaaaaatcc aagcttgtcc atcgttcttt
    16321 agctcttgct aactgaacga catcatgtgc tgtcttatcc acgatctatc catcctttct
    16381 gtgtatgcaa ttcaagaagc gtatggattt tctgtttcaa ttccatgcgg ggaacaatct
    16441 gatcgacaaa accatgagat aataagaatt cagccttttg gaaatcttct ggaagttcct
    16501 gcttgatcgt ctgttcgatg acgcgtcttc cagcaaaacc gatcaagctt tggggttctg
    16561 ctagaataat atcgccttcc attgcaaaac tggcagttac tcctccggtc gtcgggtccg
    16621 ttaaaacagt tagataaaaa agaccttcat tgctatgccg tttgacagca gcagagattt
    16681 ttgccatctg cattagagaa aagattcctt cttgcatccg tgcgccacct gaagctgtga
    16741 acaagacgac tggaagactt tcctttgttg ctcgttcgaa taatctggtg atcttttctc
    16801 cgacaatcgt tcccatactt cccatgataa aattaggatc catcactcca ataatgaagg
    16861 gaatcccctg aatggttgct ttaccagtga ggactgcttc atgaagtcct gttttatctt
    16921 gcattttttt aattttttcc gtatattcgg gaaatgctag cggatctttg gttacaagat
    16981 ccgtatccca ttcttcaaaa cttttttcat caataatcaa agctagacgc tgccatgcac
    17041 cgattcgaaa agcgtatccg caatgagggc atactttttc ttcaccgatg tctttcgtat
    17101 aaaggatatg tttgcaattt ggacactttg cccacatgtt atcaggaaca gatggcgagt
    17161 tagcaggttt gctctctcta ttaggattga tccgaatata tttctttttc ttaaacagag
    17221 ccatctatgc gcctcctatc tccgtttctg gtgtccaatt cggtaaaaat tcttcttgta
    17281 aaaatgctgt gctgtaatca cctgctatga ctgcaggatg actaatcaaa tccatctgaa
    17341 attctgcgtt cgtgatgatt ccttctgtga taaattcact taaggctcgc tgcatcttca
    17401 ttaatgcttc aaaacgcgta tttccatgga cgattatttt tgcaatcatt gaatcataat
    17461 atggcgggat cgtatatccc gggtaaactg cactgtctac tcgcagtccc atcccacctg
    17521 ctggaagcag taagttttgg atcttccctg gagaaggagc aaaatggaaa gcaggatttt
    17581 ctgcattaat ccggcattcg attgcgtgtc cttggaatac tacttcttct tgacacacat
    17641 tcaaaggctc accggctgct atctccacct gtttttttac taaatcgatt cctgtgacca
    17701 tttctgttac tggatgttcc acttggattc gagtattcat ttccatgaaa taaaaatcgc
    17761 cttcttcatc catcagaaac tcgatcgttc cggcattttc ataattgact gctttagctg
    17821 ctcgaacagc agcgtctcct agtgcttctc tttttgtttg tgagatcact acagaaggag
    17881 attcttccag tactttttga ttgttgcgtt gtaaagaaca atctcgctcg cctaaatgaa
    17941 tgacatgacc aaatcgatca cctaagatct gaacttctat atggcgagca ggataaatga
    18001 ttttttccaa atacatatca tcatttccaa atgccgctgc tgcttcttgc tgagctgaag
    18061 aaaaatgctg tgggagctct tcttttgatt gaactttccg aatgcctttc ccgccaccac
    18121 ctgcagctgc tttcagcatc actggataac caattctgtc tgctatttcc aatgcttctt
    18181 ctactgtaga taatacacca gtacttcctg gaatgactgg gacatttgct tcttgcatca
    18241 attgacgcgc attgatctta tttcccattg catcgatcgt tgcactttta ggaccaataa
    18301 atgtgatatt gcactcttca cacatggagg caaatcggct attttcagat aaaaaaccaa
    18361 atcctggatg aattgcttcg gcttttgtca cgattgcagc gctcagtact tcctgaacat
    18421 tcagatatga atcaacggct tttgccgggc caatgcagat tgcttcatct gctaactgtg
    18481 tatgaagtgc ttcggcatct gcttctgaat atatcgctac ggtttggatc cctagttcgc
    18541 ggcatgcacg aatgatacgt acagcgattt caccgcggtt agctatcaat actttagaaa
    18601 acatatttca cctatccaat cataaaggtt aattccgctt cggctacttt tttaccgtct
    18661 actttagcga ttcctttgcc tattccggct gaagctttca ctttcaatat ctcaacttca
    18721 aggtataagg tatctcccgg tgtaactttc ttacggaatt ttgctttgtc caatccgccg
    18781 aaataagccg tctttccctt gaattgttca agagaaagta atgcaactgc tcctgcttga
    18841 gccattgctt caacaatcaa tacccctggc ataacaggtt cttctggaaa atgtccttga
    18901 aaaaagggct cattgatcgt tacatttttc ttagcaacga tccgttctcc ttcaaccatt
    18961 tcttccactc gatcaatcaa aagcattgga taacgatgtg gaatgatttc ttttatttct
    19021 tgtatgttca ttgttttccc tctttcctgc tttgcttatt tttgctgaat cctaaagagt
    19081 ggctgtccat attcgacaac tgactcgttt tctacaagga tttctgtgat cactccgtcg
    19141 gcctcactag ttatctcatt catcagtttc atcgcttcaa taatgcagat aacttctcct
    19201 ttggcaactt gatcacctac ttttttgaaa gctggtttgt cgggcgctgg ttgcagataa
    19261 acgattccca cgattggcga aacaacctcg attccatcaa atactgccga ttctttttct
    19321 ttcattattt ctggagcagt tgttgcttgt tcaggtatga cattgactgg ctccgaaact
    19381 ggcaacgttt cgtttgtttg aaccatattc atgcctcgac ttgttttatt tttattcata
    19441 tacaattcaa attgaccttc acgcaaatcg aattccgtta gcgaggattg atcaaattga
    19501 ctgactaatt ctctgatttc attgatatcc aaaattattc ctcccagcgt ttcatgcaca
    19561 gaaccgcatt atgtccgcca aaccctaatg aattactcat tgcataagta aaacttgcag
    19621 gtttgctttc gtttttgaca actgtcaagt caatctcagg atcttgtttt tctacattga
    19681 tcgtaggtgg gataaattga tgttctaatg ccagcaaagt tgccaaggct tcgatcccgc
    19741 cggctgctcc caataaatgt ccagtcatcg atttcgtgct gctgacgtaa gtatctctga
    19801 aattttcacc taatgcgatt tggattgctt ttgcttctgc ctggtcattg gctggtgtac
    19861 ttgttccgtg agcattgata tatccgactt gttccggctg tacaccagct tcttccatcg
    19921 caagcttcat tgctttagat gcaccagaac catctggagt aggagctgtc atatggtaag
    19981 cgtcacagtt tgcaccgtat ccaacgattt ctccatagat tttggcaccg cgagcttgtg
    20041 catgttctaa agattcaaga actagaacgc ctgctccttc acccatcaca aaaccattcc
    20101 gattttcgtc aaacggaatc gaaccacgat taggatcagt tgattctgag agtgctgtta
    20161 aagctgcaaa tccagcaatc cccatctcac aaatcgttgc ttctgttcct ccagcaagaa
    20221 tgacatcaga atagccatgt ttgatgttac ggaatgcttc cccaattgaa ttcgttccgc
    20281 tagcacaagc tgttacgata gctgtacaaa taccttttgc acctacacgc aaagcaatat
    20341 ttccagctgc catgttggca atcgccattg gtacgaacat tggagaaact cgttttgcac
    20401 ctttttcatg tagacgaata acttggtttt cgattgttgg aagaccaccg atcccagatc
    20461 cgatgatgac gccaaaccgg tcttgattca ttttttcttt atctaaaccg ctcatctcca
    20521 ttgcttctaa agcagcgtag attccataga tcgaaaacat atccattcgt ttgctatctt
    20581 ttttaataaa atatttatcg taagggaaat ctttgacttc acccgctaag gtaatccctg
    20641 tttctgaagc atcaaattta gtgatcggtg cgatgccatt cgtcccctct tttaagctat
    20701 tcaaaaagct gtctgcgtca tttccaatag gtgaagtgac tccatagcca gtaattacca
    20761 ctcgattcat ttgtttgctc tccttttctt atccgtgcat gaccaatccg ccatcgacat
    20821 tgatgacttg tccggtgata tatggatttt gtgctaagaa aactgctgtt tgtgcaatat
    20881 cttctacttg tccgaaacgc tgcatcggaa tttgcttttc cgcttgttcc ttgactttgt
    20941 ctgctaaaac ttccgtcata tcagttgtga tgaatcctgg cgcaatggca ttacatgtaa
    21001 tgcctctagt tgcagcttct cgtgccacag attttgttaa tcctactacg ccagctttac
    21061 tagctgcata atttgcttga ccaatatttc caatcaaccc agatacacta gagagattaa
    21121 tgatggcccc ttctcgctgc ttcatcattt ttttcaatac gtgctgcgtc atattgaagg
    21181 ttccaatcaa attgatatcc agacattttt tgaaatcttc tgcatccatt cgcatcacaa
    21241 gtttgtcatt tgtgattccg gcattgttta ctaacacatg gatcgatcca agcttttctt
    21301 ctgcttcttt gatcatttgt cccgctttct cataatcaga gatgtcaccg gaaactccta
    21361 cgcattttac accgaatgct tcgatttctt ctatcttttc ttttggaatc tctccgcgac
    21421 cattcaaaat gatatttgct ccagcttttg caaaagctaa ggccatcgct ttgccgattc
    21481 ctcttgtact acctgtgata aatacatttt ttccttttac atccataacg ttcctcctta
    21541 tagtattgct attgtttcat caaatgtctg cttattctca acacgcagaa ctggtattgt
    21601 tttatcgatt tttttcataa atccgcttaa tacttttccg gggccgactt cgatgacttg
    21661 ttcgatgccg attgttttta acttatggat actctcatag aaacgaacag gttgcatgac
    21721 ttgctgttca agtagtcccg cgattgtttc tttcttcatt atttccgttg ttgtgttgct
    21781 tatgatagga aaagaaggtt cagagaattg aatctgactt aggtccttcg ccagtttttt
    21841 tgctgccggt tctaaaatag ctgtatgaaa aggcccgctg acatttagag ggatcattct
    21901 tttgaaccct ttttctttta atagtaaaac agcttcgtct actgcttttt cttcgccacc
    21961 aatcacgatc tgctgaggtg tattataatt tgcaggagat acgatgccgt acttgctagc
    22021 ttcatgacag ctttcctcga tcgtttcaat cggcgcattc atcactgcaa ccattttccc
    22081 gcttccagct ggggcagctt ctgtcatata agcgcctctt tttgctacta acgcaactgc
    22141 ttcagtgaag gatagcgcat tactagctac taatgccgaa tattctccta aactcagtcc
    22201 taaagctgca tctgggatga ttccatgctc cttcaataag cgataatacg cgatgctgac
    22261 tgttagaata gctggctgtg tatattgcgt ctgatccaaa cgttcatttt ctgtaaagca
    22321 aagttcagcc atatcgtagc cgagaatctc acttgcttca tcaaatgtct gctttacaac
    22381 ggcttcttca tataaatctt ttcccatacc ttgatattgt gcaccttggc cactaaataa
    22441 gaatgctgtt ttcatgtttt tctccaatat atccagaata tatgtttgat tcttcctatt
    22501 caaaaaggcc gagacattcc tatttcagga aatgtcccag cccccaacct aattttaatg
    22561 attatgcagt ttgtttttct acgtaagtca ctaaatcttg aaccgttttg attccgtctt
    22621 ctgtttcgat tttcacgtca aattcatctt caatttcatt gatgatttgg aataaatcca
    22681 agctgtcagc ttctaagtct tcttggatgt cagtagtcaa tttgatttct tcagtttctt
    22741 ttcctaattc ttctgcgatg atttcttgaa ttttttcgaa taccataata atatattcct
    22801 ccgatattgt ttgcttttta tttttataat ttaacagtct acaactccat gagaatactt
    22861 ccccatgtta aacctccgcc atagcctgta aatattactt tctgctgttt tcctaaggtg
    22921 atctttccac tagaaactgc ttcatccaat aagataggga tgcttgcagc agatgtattc
    22981 ccatatttat ccatattggt caggaacttt tcttgcggca tctttacttt tcgggcaatt
    23041 ttctcaataa ttctgaggtt tgcctgatgc aaaagcagat aatcaactgg tttgtctttc
    23101 atgacttctt ggatattgtt tgcaacgtct cgtacggcaa aatcaaaaat atctctgcca
    23161 gtcatttgca aataatacga accttctgaa tcttctgaat agaacggatt tttattttgc
    23221 tggtagccag cggtcaatga gctacttctg gtaccgtcag ctgctaattt ttctttcagc
    23281 aattttttct gtggattcgc ttctaagaga atcccacctg ctccatcgcc aaacaacaca
    23341 gcagtcgtac gatcagacca atcgattagc ttagatagtg tttcaccacc aatcaccagt
    23401 cccttagttg agccgcagcg gatcattttt tcagccatgc ttaacgcata aacaaatcct
    23461 gagcacgcag cactgatatc aaaagcgata gcatgagttg ctcccaattt cccttgtact
    23521 tgtgctgcta cagatggtgt cgtgtaatcg ggcgacattg ttgctactaa aataaaatcc
    23581 aaatctttag ggtttagatt tttctgtttt atcaattttt ccgccactaa aatgcataaa
    23641 tcagaagtct cctgatttgt tacacatctt cgttcacgaa tacccgtcct tgacgaaatc
    23701 cattcatcag aggtatccat catcttggaa agatcattat tagtaataat cttttcagga
    23761 aggacgctgg ctgttgcagt aatcattcca aattgttcca ttaaatatcc tcacttatag
    23821 tcttgcaaga agtcgtgcaa gtttttcagt gcatccagca aggcatgctg ttcctccgta
    23881 gccattccgt ctaagatgtt cttgaccatt tcacgatgaa aatgctgatg gacccgaaat
    23941 agtaactttc cttttttcgt tagtcccaac tttacaacgc ggcggtcatc ttcactgcgg
    24001 atacgttcga catagccttt ttttactaac ttgttaatag cagtggtcaa ggtcccaaca
    24061 gtaattgata gttctttggc tacttctgaa gttgtttttt tcttgtacat cccgattgcc
    24121 tcgatcgtgt gcatctctgt gattgacaga tctttgaatt gagatttttt cagctcagac
    24181 tcttcgattg tcaaaatatc attgaagaca ctaacaagat aatcatttac tgtttttaaa
    24241 tctggttcca tgttccaccg tccactaatt agtttgatta tcaaatcttt tgatgttcaa
    24301 actatatctt aacttttttc aaaatgcaac cttaaaagat cattttttta ctatatgagc
    24361 tttttttaag attttactca tttaaaacaa ctgataaatc agcatttata atttctttta
    24421 ttagaaaaat catctatctc acatattttg attatcaaag tattttctgt gaacagaact
    24481 atagaattcc ctaaaacttg tccattattt caaaatttgt tatagtcttt ttattcaaag
    24541 cgtaaaagga gatcctatgt taaaagaaaa aatgaaaact ctccccatgc tgccgggtgt
    24601 ctatcttatg aaagaccgag atggtaaggt catctatgtt ggtaaagcaa aacggctcaa
    24661 aaatagagta agcagctatt ttcatcagaa taaacagcat tcaaaaaaag tattacgtat
    24721 gattcatcat ataacagatt ttgatttcgt cgtagtagac acggaattag atgctttatt
    24781 gctcgagtgt caattgatcc aacattaccg tcctttttat aaccgacaaa tgaattattt
    24841 cagtaattat aattatgtac atattaccaa taagggattt gtattaacag atactcctac
    24901 ggctcgaaca tacgggcctt ttcgtctcta taaaaaaatg ccgtctattt tgcgtataat
    24961 ggaagaaact tatcaaatgc cttggttgtc tgaaattagt ttgttagctt tgcgagtcca
    25021 gcttcctgac ctacaggaaa tgacttttga acagaaaaaa aaggaactcc aagggctgtt
    25081 tcaaggccga aataaaaagc tactgactta cttgaaaaaa agacaacaac atttcatcta
    25141 tcagttgaat ttcgaaaaag ccggtatgct tcaaaaagat atcgaattag ttacttattt
    25201 tattagacgg atccaggaac aaaagcagtt tttaagaaca ccatcgctca ccttcagcat
    25261 gccattagca gcagatgaga gtcagaaaaa gcactacctc gtttgttatg gtcaacttgc
    25321 agaaacaatg attacctctg gtgacgtttc tcctgacttc tattatgaaa agaaagaagc
    25381 tcatttatct ttgaaacgtc aattgtcaaa agaagaaatc gatcctgtac aaatcttgat
    25441 cagttaccgc aaaaaattag aaaaagaaca gtttgaaatt gaactgttaa acaaaaaaga
    25501 agctgaaaag caactaaatt agttgcttct cggcttcttt taggcatctt caacttcaaa
    25561 tgtcaattat cctaaaattt attggattaa gtcatagatt tccatcgcta cgatatcgat
    25621 attatcaaat tcgtattgct gatgagtatc tgtttcagtt aattcaaatg tatcggtcgc
    25681 tttatcataa gttactgtac acttctctac gccttctttt tcaaaacggc gaacttgcag
    25741 ttcattatct gctgactcga ccatagcctc cagtcgtttt atgattgcga ctaattgtga
    25801 atgtgtcatc ggaggtcctc cttttcttat ttctgttata ttgtatcaaa agcatagcct
    25861 acttgcattg attttctcta aaaaaactcg ttttttatga ttttttttct ggtatttttc
    25921 cttcaggcca ccaaagtttg atcaaagctt gggttccgtc attctcaaaa cctttatctg
    25981 ccaactcttc atatagtttc aatgcttggg tagttgctgg caatacaaga tccatttttt
    26041 ctgcttcttc taatgcaatc tttaaatctt tgataaaatg tttgacaaaa aaaccaggtg
    26101 tgtaatcttc ttttaaaata cgaggagaat aattgcttaa agaccagtta gctgcacttc
    26161 cacctgaaag cgtctcaatc actttcttta aatcaagtcc gtttttttgt gcatagacaa
    26221 gcatttccgt cattcctgtc atcgtacctg caatcatgat ctgattagcc atttttgtat
    26281 gctgaccttt cccagcagaa ccatgcaatg taaatgtcgt accaaattct ttgaataaag
    26341 gcagtacttg atcataaacg gcttcttctc caccgaccat gatcgtcagt gtaccattct
    26401 ttgctcctaa gtcaccaccg gataccggtg catctaacgc atctgcgcct ttttcttttg
    26461 ctgtttttgc aattttttct gccaggcttg gtgtacttgt agtcaaatca actaaaatat
    26521 gtcctgagat atctgcagaa aaaatccccg actgtccata gtagatttct tctacatctt
    26581 tggggtaacc taccattgta aagagaatat tactttgttc tgctaccgct tttggtgtat
    26641 ctgcccagat agctccttct gttactaaag gatcagcttt tgcttttgtc cgattataga
    26701 cagctacttc gtgtcctgct tctagtagat ggcgtgcgac agcacttccc atgacgcctg
    26761 ttccgataaa accaagtttc attttttcga cctcctaaaa atcaaaaatc cttgcttcta
    26821 tgctagtata cgctagaaac aaggattttt tcataaaaaa tgtttgaatt ttatctttta
    26881 aatgaattta attttatttt gattcgttca atcgagtctt cttcttcttt tcttcgcatc
    26941 tcttcttcat gataaacaac catgtcttga taaaattcga tcatagcttc gccgaaatgt
    27001 gtagatgaaa tatcataaag tttagcttct aaaacttttg gatctttagg aacttcactg
    27061 gaaatataat caataagtgc tggtgcaaag tcttcgtcgg tttcaaaagt tttccctaat
    27121 gaaggatgat cgaacaatcg gttcaaataa gcatttcctt ccacgacaca aggtgttccg
    27181 gctgccatcg cttctgtata agtaagccct tgtgtttctg aagtagaagc actgacaaaa
    27241 taatctgccg ctttataata aagtgctaca tcattgttgt ccacttctcc tgtgaactgc
    27301 acaaattctt ctaactgcag ttctgagatc aattcctcta actcttctac ataaggtcct
    27361 tttcctacga taactaatct ggcgttagga taagcggaga tgacctgagg aaacccatta
    27421 atcaaggctt ggatattttt ctcataagaa atcctgctta aagaaagaat catcaaatgg
    27481 ttttcctgaa gacctagtga ctcccttaat ttgctgatat cctgctgagt gatatcagaa
    27541 cgtttgaatt tttcaatgtc gataccagta ggaatcacgc gaagcggtgc tattacacca
    27601 tagctgcgta atgtatcaat aacacgttca cttggacaaa ctacacctgt cgtatgattt
    27661 gcaaataatc tagacaagta ttttacatgg gattgcctga tcacttttcc tttaccgata
    27721 taatgaaggt agtcttcata catcgtatgg taagtatgga tcagaggtat tttcaacttc
    27781 ttagctacca tcttcccaag tatccctgct ccgaattctg tatgggtatg aataagatct
    27841 agttctagtt ctttggcaac caaataagca taccacatgc ctctaacaac aactcttcga
    27901 tccttgaaag aaataaatgg tacacttggc attcgaatca catctttttc caacttatcc
    27961 gcattaggat cggtcgttgt aaaaatatag acttcatgcc catgtctttc taattcttgt
    28021 tttaatgttt tgatcgatgt agcaactccg ctgacttgcg gaaagtaggt atcggtaaaa
    28081 aagccgattt tcatgttttt cgcctccaaa ctagtccttg acctgattta ctttttttaa
    28141 tttgctagag actttttcat tcagtacact ttcgtataca tttttaagtt cttcaccgat
    28201 tttattgata cttcgctctt ttgctgtttg ataaccggct tgtgtcgtac tcggtagttc
    28261 ttgattggta atctgttgga tcagtcggat aaattcttcg tttgtcttcc ccatatagca
    28321 gttcttgcta tcttctaacc agccattata cactggaata tctcgaacaa gtacgttttg
    28381 tttgcttgct aaagcttcta aaacaacgat cccttctgtc tcttcataag aagggaaaaa
    28441 gaatagatct gcacctgaat acgcaccttc tatgatctct ccacgaatgt aaccaggaaa
    28501 caggacattt tcaggatgat cttcttttac aattttccgg atgttccgag gaatcgagta
    28561 catgggaaca tgaccaaacc aaataaatgt gtattcgggc atcttcttag caatttctac
    28621 gaaatcaatg attcctttac gttcgaaaaa caaaccgaca caaatgatta ctttttgatc
    28681 cggagacagt ttgaaatatt ctctgaactt ttgttctttc attggatcag ggtgatattt
    28741 ctctaagtcg atcccattgg aaatagcttg aatcggcaca cggataccat agctttccaa
    28801 caactgtttt gaataaggtg ttggcgtgat cagatagtcc gctttttggt acaatcctac
    28861 cagatatttt tttacgatag gagaaagctg gttcgatctg ataaaggaat ttcggaaatc
    28921 ttcctctgta gaatgcgcat gatagacaac tttttttcct tctcttctgg ctttattgac
    28981 catattatga ctattgattc cgtatgtatt gatgtgcagg atgtcataat cttctttttc
    29041 atctagtgta taagagatac cgacttccgt cagagcacgt ttttgatgat caagcgcacg
    29101 cccgattcca gattttgcaa gcatcttttc actttcaaaa tataataata ccttcacctt
    29161 acgtccccct tcacttatat agtataacat agcctacaaa ctgtcactca aacttaagcc
    29221 ctatttttgt ctattcttac tgacaaaaac gttttcttaa aaaagaacaa aaaaactggc
    29281 gtagctcttt tacaagccac accagctttt gatacgttgt ttattttaca tattcatgaa
    29341 caagttcaac gacttcttcc atcatatcgc attctttcaa tgcacgatca gcaagttcag
    29401 ccattttcgc tgtgtccaag cgtttcatta aactacgcgt tttaagaata gatgtcgcac
    29461 tcattgagaa ctcatctaga cccataccta ctagcaatgg aacagctgtt tgatctccag
    29521 ccatttctcc acacatacct gcccattttc cttcagcgtg tgctgcatca attacatttt
    29581 tgatcaaacg taaaattgat gggttatatg gttggtacaa gtaagaaacg cgttcgttca
    29641 tacggtctgc tgccattgtg tattgaatca aatcgttcgt acctacagag aagaaatcta
    29701 cttcttttgc aaacttgtct gctaagactg ctgctgctgg aatctcgatc atgatgccga
    29761 cttggatcgt atcagatact tccttgcctt cacttatcaa tttttgtttt tcttcttcaa
    29821 agatcgcttt tgctgcgcgg aattctttga gtgtagctac catagggaac atgatacgta
    29881 aattaccatg aacagatgca cgaagcaatg cacgcatttg tgtacggaac atttcgtcgc
    29941 cttgttcaga taaactgata cgcaatgcac gatatcctaa gaatggattc atttcatgag
    30001 gtaattgcag atatggtagt tctttatctc caccgatgtc cattgtacga acaactacag
    30061 gttttccttc cataccttct aatacagctt tgtaagcttc atattggtca tcttctgttg
    30121 ggaagtctgg agaatccata tacaggaatt cagtacggta cagaccaact gcttctccac
    30181 cattattatg gacaccaact agatcttttg gtgttccgat gtttgcagct aattcaaaat
    30241 gcttgccgtc agctgtgaca gtttctgcat tttttaattt ttcccattct gctttttgtg
    30301 ctgcgtaatc tgcacctgct ttttcaaatt cagctttttg ttcatctgta ggatcgatga
    30361 ttacatcgcc ttcgatcccg ttgacagcca aaatatcgcc ttctttgact ttagcagtaa
    30421 tttcttttgt cccaacgatt gctggaattt ctaaagaacg tgccatgata gcagaatgtg
    30481 aagtacgtcc accaatgtct gttacaaacg cttttacaaa attgcgatct aattgtgctg
    30541 tatcacttgg agtcaagtca tgtgcaacaa cgaccacttc ttcgttgatc attgatggat
    30601 ttggtaaagt aacgcctaat aagtgcgcta aaatacgttt agcaacgtca cgaatatctg
    30661 cagcacgctc ttgcatataa gcattatctt ccattgcttc gaacataccg atatacatat
    30721 ccgttacttc ttttagcgct gattcagcat ttacgctgtt gtctttaata ttttgcttga
    30781 tttgacctac catttctgga tctgaaagaa ccatcaaatg ggcatcaaat acttgcgctt
    30841 ctgcttcacc taagctttgc gctgcttttt cacgaatttg ctgcaattct tcagtagatt
    30901 tagctaatgc agcatccaaa cgagcttctt cagccgcagt atcttctact gttgccttac
    30961 tgaatgttaa atccggttga actagcaggt aagcttttgc aacggctaca ccgtcactag
    31021 cggcaatccc ttttagcatt tcaaccatta ttcagataag ccttctttct tcattgtttc
    31081 aacgattgct gccattgcat cagcttcgtc agcaccttct gcagtaatag taacatcaga
    31141 accttgacct acacctaaag acataacgcc catgattgat ttcaagttta ctgatttacc
    31201 tttatactct aagtttacat cagagttaaa tttgcttgct gtttgtacta atagtgtagc
    31261 tggacgagcg tggatcccag tttctgctac tacgtgaaat tctttctttt ccatattaat
    31321 cggtctcctt taagtgagtg ttgtttttat gtgagggttt tcttttttag taattcagag
    31381 aatcctaaca aatgccaccc tttcatctgt aaagattaac attttttttc gttagataca
    31441 acagttttca ttcaatttca gataaaagta ttcaaattat tccggattct ttttcatcct
    31501 tttcttcaca ttttataaca aacgtgttta tttccttttt cttgtcgctt tctcttctcc
    31561 tgacgtttat cattctttcc tttgaccctc tttgttttca tatgaaacga attacttgct
    31621 tcccttttta tttttagtat aataagagtc aaaggtcagg aatggtcaat agagatttca
    31681 ccttttctac ctcataaatc tcttaaaaaa ctaggggtta ttcttttacc tcatgaaaaa
    31741 cgagatgtaa aatatggatg tacccatttt tgtgaaagga cgtgaatgat tcatgctttg
    31801 tcaaaactgc ggcaagaatg aggcaacgat tcacttgtat gccactgtca atggtcagcg
    31861 gacacaactc gattactgtc agagctgtta tcaaaaaatc aaaaatcaac aaaatggagg
    31921 tctgactaat atggcccaaa atgatccatt tggatttggc agtttggacg atcttttccg
    31981 ttccatgtct cgccaaatgc aacagcaagg aaattatgag caaacaccac caacacaatt
    32041 tggcggaaac aacaacttca atggtggtca gccacctcaa ggcaatacag aaggtttatt
    32101 gggagaatac ggaatcaata tcacagaaca agcacgacaa ggtgatatcg atcctgtgat
    32161 cggacgcgat gacgaaatca aacgagtcat tgaaatttta aatcgccgaa ccaagaacaa
    32221 tcctgtcttg attggagaac caggtgttgg taaaacagca gttgttgaag gtttagcaca
    32281 aaaaatcgta gatggtgatg taccgcaaaa attaatggac aaagaagtca ttcgtttaga
    32341 tgtcgtatct ttagtccaag gtactggtat acgaggacaa tttgaagaac gtatgcaaaa
    32401 attgattgaa gagatccgtc aagcagaaaa tgtgatccta ttcatagatg aagttcacga
    32461 aatcgtcggt gctggttctg ctggtgatgg aaatatggat gctggtaata ttttaaaacc
    32521 agctttagct cgaggagaat tgcaaatggt tggtgctact accttaaatg agtaccgcat
    32581 catcgaaaaa gacgctgctt tagaacgtcg tatgcaacct gtacgggtag atgaaccaac
    32641 tgtcgaagaa acgatcagta ttttgaaagg tttgcaaaaa cgttatgaag actatcatca
    32701 tgtaaaatat actgatgagg ccatcgaagc agccgcaact ttatccaatc gttacgtcca
    32761 agatcgcttc ttgccggata aagccatcga tttgctagat gaaacaggtt ctaagaaaaa
    32821 cttgacgatc caaatcgttg atcctaaaac aatcgagaaa aaactgcaag aagcagaaga
    32881 acaaaaagtt ttagcttctc gagaagaaga tttcgaaaaa gcagcttatt atcgcgatca
    32941 gatcaataaa cttcaaaaaa tgaaagaacg tcagctcact gaagaggaaa cacctgtgat
    33001 taccgaaaaa gatatggaaa aaatcgttga acaacggaca ggtattccag tgggtgaatt
    33061 aaaagaaaaa gaacagacac aactgaaaaa cttagcagat gacttgaaag ctcatgtcat
    33121 cggacaagat aacgctgtag atcgagtagc gaaagcgatt cgccgaaacc gtgttggatt
    33181 aaacaaacag aatcgtccaa tcggctcctt cttatttgtt ggaccaactg gtgtaggtaa
    33241 aacagagctt gcgaaacaac ttgcctacga actattcggt tcacaagatt caatgattcg
    33301 tttcgatatg tctgaatata tggaaaaaca tagtgtctct aaattgattg gttctcctcc
    33361 aggttatgtc ggatacgaag aagctggtca attaacagaa aaagtacgga gaaatcctta
    33421 cagtcttgtc ttgttagatg aagtagaaaa agctcatcca gatgttttgc atatgttctt
    33481 gcaaatctta gatgatggtc gattgacaga tgcacaagga agaacggtca gctttaaaga
    33541 tacgatcatc attatgacaa gtaatgccgg aactggtaaa gtagaagcaa acgttggttt
    33601 tggtgcggca cgcgaaggtg ttactcgttc tgtattgaac caattaaaca actactttac
    33661 accagaattt ctgaaccgtt ttgacgggat catcgaattc agtgcattat caaaagaaaa
    33721 cttgatgaca atcgtcacac taatgctaga cgatgtcaac caaatgctgg cagcacagca
    33781 acttcacatc gaagttccta cgaatgtcaa agaaaaatta gttgacttag gctatgatcc
    33841 atctatgggt gctcgtcctc ttcgacgcac gatccaagaa caaatcgaag atggtatcgc
    33901 tgaattttat cttgatcacc cttctatcca tgagttgaaa gcaaaactgg ataaagatgg
    33961 aaaaatcatc gttacttcta aaccagaacg tttggctaaa gaatcagccg aagaaacggc
    34021 tgaataaatc cagttttata gcgtgagacg gtatttcttt gagaaatgcc gtctcattct
    34081 tttttcagaa aagtcaaaat actgttcatt ttataaaaaa gaaattataa taagagaaac
    34141 aagcaattaa aaatacataa aagaggtgag cgccatgaaa ttggtaaatg taacaaacag
    34201 ccattcccgt cttgtattaa accagcttga aaacactgat gcccatctag tcaaggtcta
    34261 cacagccgga aataccacta ttgtctacac tgaagcccct gaacataatg aaattctgct
    34321 gatcaatgac aaacgtaaaa tccagccgaa agaaatcgaa gatgctaaaa attatttctt
    34381 agataaaatc aaagacgccg tttaccacga ggatgaaatc aaagtaatcg aattggcagg
    34441 ccttgttgaa atctcgattc caaaacatga attaggcgct acattagccg tgtaaacaaa
    34501 ttttgaacat aataattaaa gagcgtggga caaaagtaaa gaacactttt gtctcacgct
    34561 ctaaacacgt ataaacggcg aaagcagaag caactccttc ggaaataagc tgaaattcac
    34621 gaaaattgct tttcaaattt ttgtgaattc cagcttattt cttggagtta aacgcttctg
    34681 tctcagcctc tttttctttc tagctttttg atttttctct tttcttttgt acttttctct
    34741 tttcattttc agttctacgc gtgtctttat ttttaacttt ttcctcttta tggatgattg
    34801 atcgtacttt ttgtgcaatt tgctcgtttt tgtcccagtc ttttacatct aataatcgac
    34861 ataatcgtaa catctcttct tttttctgtt tttttctttc acgtctttgc cattctgttt
    34921 ccatgtgtca cactctcctt tctttaatca tatgtacgca aaataatttt tatatttttt
    34981 tgattagaca tttctatgat tttaatatag taaaaagagc cgtcacggaa aatccgtcac
    35041 ggctctaaac aaaatatgag aggctgtttt tgtttggcta ttcttattac ttgatgcagg
    35101 gcagcttgtg tcaagacttc tttacatcaa actttttaat tttacattgg gatatttatc
    35161 cgcaaaccag cgttctgcaa attggttctc gaataagaac aacggttggt cgaaacggtc
    35221 acgagccaag atattgcgac ttgaactcat cttctcatcc aaatcttctg gatcgatcca
    35281 gcgagcgatt ttgtgtccca ttggagacat gattacttcg gcgttatact catttaacat
    35341 acgatattgg aatacttcga attgtagctg accaacagct ccaatgatat attcttccgt
    35401 tagatatgtt ttataaagct gaatcgctcc ttcttgaact aattgataga ttcctttgtg
    35461 gaaggatttt tgtttcatga cattttttgc agtcactttc ataaacagct ctggagtaaa
    35521 tgaagggagt tcttcataag caacttttag ttttccttcg aacaatgtat ccccaatctg
    35581 ataattgcct gtatcatata caccgatgat atcgcctgct actgcttttt cgacgttttc
    35641 tctcgaatct gccataaatt gtgtgacatt gcttaatttc agttttttat ttgtacgttc
    35701 caaccagaca tccattcctc gttcgaatgt tccagaacag attcggacaa aagcgattcg
    35761 gtcacgatgg gctggattca tatttgcttg gatcttgaat acgaaacctg aaaattcttc
    35821 ctcataagga cttaccatct gatcatcttg tgttttgtgt ccataaggag ctggtgccaa
    35881 ttcaacgaaa gtctctaaaa aagtctgtac accgaagtta gtcaatgcag aaccaaaaaa
    35941 tactggtgtc tgatcgccac gagcaatttt ttcttgatta aatgcatctc cagcctcttt
    36001 gattagttct acttcttcta agacttgttc atataaggaa ttttcagtta gaggatgatt
    36061 ttcgggaagc agtccatctt catccaattc tactaatcgt tcatcctgat aattttccgg
    36121 acgataaaac tctacacgat tatggtagat atcataaaga ccttctagcc ctttacccat
    36181 accgattggc caattcatcg gataagattc gatatctaat agctcttcta attcttctaa
    36241 caattccaat ggttcacgac catcacgatc tagtttgttg ataaaagtaa atatcgggat
    36301 gccacgtttt tttacaactt ggaataattt ctttgtctgt gcttcgatcc cttttgcact
    36361 atcgattacc atgaccgcac tatccacggc catcaaagta cgataagtat cttcagaaaa
    36421 atcttcatgt cctggtgtat ccaagatatt tactcgtttc ccttgataat caaactgcat
    36481 aacagaacta gtaacagaaa tcccacgttg tttctcgatt tccatccagt ctgatttggc
    36541 aaaattacct gtttttttgc cttttacggt cccggcttga cggatagccc caccaaacaa
    36601 tagtaattgt tctgtaatcg ttgttttccc agcatccgga tgggaaatga tcgcaaaagt
    36661 tctgcgattg tccacttgtt gctttaattt tggattattc ataacctaac tccatttctt
    36721 ccattcaatt atttatattt tctctaggca cagattgtcc gatctcttaa agaaagacaa
    36781 tttcatatag ggctgtgaca aaagccgtgt agcagtctct ttttccgagt aaacggcgtt
    36841 ctagagacag cctatcagca ataagcccac ccaagccaaa aatacgaaaa gctgtttttg
    36901 cttggctgct cttattactt aatgcaggat agctttttca caacctttgt caactactac
    36961 aactgaatca gtatagcatg gattcagcga atgaaaaagc caccaaacca taagagtcaa
    37021 atattttttt gtcagctgac taaaagaaaa gacgtgttgc ttgtttattc aagcaacacg
    37081 tctttcataa ccaagtttcc aattatcttc ttggctcgtc atcttcgaat tcttttctga
    37141 agtatcttcg ttcttcttca ggttccgctt ctgtttcttc cggatcatga aaaatgacac
    37201 ggattttaag gattcgagaa ccttccattt cttcagaaac cagcgtaata ttatcgacat
    37261 caaacgataa cttttcgcct tcatccggaa tcatgcctaa tgctgtaatc aaataaccag
    37321 ccatcgtatc tacatcactc atatgcagat cactgtcaaa agcttcattg aactcatcaa
    37381 tcagcatacg tccttggatg atatattcgt gttcatcgat tttttcataa agattctcaa
    37441 cttcatctga ttcatcatcg atttctccga cgatttcttc taaaaggtct tctagtgttg
    37501 ctaacccaac gacgccgcca tattcatcta ataaaatagc catctgattc tgcgtctttt
    37561 tcatttcata taacagatca tcaataaaga ccgtttcagg aacgaataaa ggctcctgca
    37621 tgattttctt gatatctaaa ttatcaaagc cgaatttatg ggcagctttt agtaaattct
    37681 ttgtatgaag gattccgact actttatctt tgtcttcgtt ataaacaggg attcttgaat
    37741 agttttcgga taaaacttca ttcacatttt cttccacagt gtcgttgata tcaatcataa
    37801 atgcatccgt tcgtgggacc atgacttctc gggcaacttt cgtatcaaga gaaaaaaccc
    37861 cttggagcat ttctaattct tcattattca atacgccttc gttttcaagc atataacgca
    37921 tttcatctct ggtcattttt gaatcttcat catcaaaagt catcggcgtg atacgcgcca
    37981 ataaacttgt ggaagcagaa agcagccaga cgaagggctt agctactaca ccaatcaagc
    38041 gtatcagccc tgaagtgaac tttgcgactt cttctgattt atttaaagca atacgtttag
    38101 ggtacaattc tccaaaaaca atcgatacat aggtcaaaat agccagcaca atgatatttg
    38161 caatattttt tgccgctgtg ccgccaccta ataccggagc taaccgttcc gataaagtat
    38221 tagctagtga agcaccagac aaaatgttga ccaaagtgat tcctacttgg attgtcgata
    38281 ggaaattatt tggattctgc aatattttta aaagcttttg agatttcaca tctccttcat
    38341 cagctttttg ctcgattcga ttcttattga tcgaaacaac agcaatttcg gaagctgcta
    38401 aaaaagcatt gatcaatgtc aaaacgatca ataataaaat ctgcgctaac agcgactgac
    38461 tctcagggtc agcattcata atcgcattct ctccttataa aattaatttt tagtttacga
    38521 tagaaaaaaa cgtggcacta tagccacgtt aaaatggtat cacaaagcaa ttttctttgc
    38581 aataaaaaca agtgtactaa aactacctac gaggtcgtag caattttctt cttgttttca
    38641 ttttgcttgt cttctttgac gattttgatt atataggaaa tgatcgtctt gcagattgcg
    38701 taaaaaggaa cacctaagaa gataccaagc aatccggcaa tatttccagc tactagaaga
    38761 acgataatga tcgttaatgg atggattttc agtgatttcc caattacatt aggataaatg
    38821 atattcccat ccaactgttg gacgattagc acaaccacac aacaaagtaa tgcttttacc
    38881 ggatcattga agactgttac tagaaatgca ggtgctagtc ctagataagg tcctaaatat
    38941 ggaattaggt ttgtcaatcc cgcaatgacc ccaaataaga aagcataatc cacaccaatt
    39001 accatatatc ctaaaaatgt gaaggtacca acgaataaac attcgattgc ttgtccgcta
    39061 atgtaattag ccaatgtttt attcagttgc cccaataact ccacaatttg gtttcttctt
    39121 ttttctggga aaaactgttg gatgtttggc actagttttt ctccgtcttt caacatatag
    39181 aacaagatga atggtgctgt aatgattact acggttgccg aagcgatcgt tccaacgatc
    39241 gaacctaaac tattggatac tccactaagg aattgctgaa tgattgtccc gtaagaaatg
    39301 tctaattgct caaaatattt attgatatct acttccttga acaaaggcaa ttcggctacc
    39361 tcttttaacc agctttctac ctgtttgatg aaatcaggca tattagatgc caatgaggaa
    39421 atttgctgta ctagacttgg gatgacacta agtaaaatcc aaataattgc tgcaactaaa
    39481 aggagcagca caattgcgac agcccatatt cttttgattt ttgctttcat caacagcttg
    39541 acaataggat tcaataaata gtaaagaaag cctgcaatca gtacaggtgc aaataacgtg
    39601 gaaaaaaatg tcccgatcgg ttcgaaaata aagtttattt ctgatgaaat catgatcaat
    39661 gcagctatga tcaataattc aagcgaccaa aacattagtt tagactgtct aagtttttca
    39721 aacaatagat ttcctccttt ctttcttact agtatatatt atattcgtta aaaattcttt
    39781 tattcttttt ttatttttga aaacttgcca tactttttat ttgttttatt ttccagtata
    39841 ctatacgaaa ggaaggtggc tagaccatga aagttgtaca aacaaaagat acaatgagca
    39901 atatttactt agatgctgta cggatcaggc atcaagtttt tgtagtcgaa cagggtgtgc
    39961 ctttgtctcg agaaatagac aaagatgaag cccattgtat ccacttcgtc ctgtactcag
    40021 ataaaaaaga accgcaagga actgtacgtc ttttgccttt agaaaacgga aaaatgaaat
    40081 tacagcggat ggcgattctt tctgaataca gacaccaagg gttaggaaaa atattgattg
    40141 aagaagcaga aaactttgct aagaatcaag gctataatac gattttatta ggggcacagt
    40201 ccacagctga aactttttac gaaaaactag gatatacagc ttacggcgat ccttttgaag
    40261 atgctggcat gcctcatatt tatatgaaaa agactttata aaaatttatt tcgaaaaaag
    40321 caaaaaacag caagcttttg agaaaaatct ctcactggct tactgttctt ttttgtgttt
    40381 acttacgcga caattgcttg taacggttat accaaatatc aatatagcct tccgagaacg
    40441 ggccatctcc attattgatc cagtcaacca gaatcttcac attttctttt aggatgaagt
    40501 caatatcgtt cgggtaattc atcattttgc tgtgcatctc atattcatcg acatccaata
    40561 gtcgtttctc gccgtcagga aataccttga tatccaagtc atagtcgata tatttcaagg
    40621 cctcatcgtc cagcaaaaaa ggtgaagcta gattacaata ataggaaacc cccttttctc
    40681 tgatcattgc tattacattg aaccagtatt ttttatgaaa ataaacaatc gctggttcgc
    40741 gcgttaccca tcggcgtcca tcagattcag tgactaatgt gtgatcattc acgccgatca
    40801 tagagtgttc gcttgttttt aataccatgg tatctcgcca cgttcgatgc aatttgccgt
    40861 cgtgcttgta actttggatc gtcacaaact ctccttcttt tggaactccc atagcaaccc
    40921 ttccttaagc agcattttgt gctttgtgtt tgggtgttca ttacaccgac atcataatta
    40981 ttatatcaat aaaaatgagc tttgcctaga aaggattcct attgtttcga tttttctcta
    41041 actgatctac cagtttcatt tggaccttag gaaaaacgac cgaatcaaat gcatcaggct
    41101 tcaaccactt cgaagttttg ttctcggtaa attcttgttc tgctccctcg gttgcccgtc
    41161 cgtaaaaaag gagaacatgc catttcagat gactaaaaat atgagtaact tctcctaaat
    41221 gtcgtgtctg ccaaacaaag agttcctgct tttcaaatgg gagattttgc tcttcttctg
    41281 ctactaggtc atcaaacaga tcgatttctg gctttgtttc ccattctttt ttcaatcgct
    41341 catactcctc ttgtgtcact tccatcattg gaaatgtcca catattcgcc agcaattttt
    41401 ggctatctct ttcttcaaaa taatacgctc cagaatgatt ttgaagagct gcactgatat
    41461 aataaacgtc ttttggcttt gctttttttg tttttacagg aaaactcgtt tggattcctc
    41521 gtttgttagc taaacaaaag gcttggatcg gacaagtctc acactttgga gaagttggtg
    41581 tacagatagc tgaacctaga tccatcattg cttggttgaa ttcacctgga tgcttttcat
    41641 caatgatttt ccgcatcgct tcatcaaaga ttttcctgct agaagctttt gcgatgtctg
    41701 cttcaatgca aaacaatctg ctgactactc gcatcacgtt gccgtcaact gcaggttctg
    41761 gaagtccaaa tgcgatactt gcaatcgcgc ctgtcgtata tggtcctatt cccttcaatg
    41821 agctaatttc ttcaggcgtt tgcggcattt ccccatcaaa ttctgacatg atctgtttag
    41881 cagcagcttg gatgttccgg gctcttgagt aataaccaag gccctcccat gcttttaaaa
    41941 gcttttcttc tggagcattt gctagctctt caattgtagg aaaccattcc atgaaacgat
    42001 aaaaataatc gatcactgtg tctactctgg tttgctgaag catgatctca gagatccaga
    42061 tacgataagg atcacgatta tagcgccaag gcaggtttct tttttcttgt tcataccatt
    42121 gaatgaactg atcttgaaat tcttttgttt ctttatctgt ccatttttcc cattctttat
    42181 tcactttcct cttccttttc cgtaatgaat cgctggatca tatccaaatc aaatcctttt
    42241 tgatataagc tttgctttac ttttagattt ctttttttag gttcaaacct taaatttctt
    42301 cgccatagtt tatctccttg tttgactaaa taatcatatt ctatttcttg atctgcttct
    42361 tgcggaagat cagctatcgc ttgttggatc acttcttgag aaaagccttt cgtcatcaat
    42421 gtttgttgga tttttctcaa taattctttt tggctttttc cgtgattttt tccaaacgct
    42481 ttttcggctg tctgatgtgc attttgaact tggtcttcaa atgtatattg gctgagcgct
    42541 tgttcaatga tttcaggttt caaacctttt tgctgcatct gctgcgctaa tttctttggt
    42601 cctttgtcac ttaagcgcat attcgtgcgc acataacttt ccccatagac caaatcatcg
    42661 acaaggtcca attcttttaa gcgggctacg attttatttc gatcttcttg aaggatttcc
    42721 ttttctttta agtatgttcg gatttctttt tccgatcgca actgataact taagtaattc
    42781 attgctaggt gaaaaccgaa atcagctccg ctactcttct tgatctcttg gatagtttct
    42841 tcgtctaatt cccgtccttt taataatcga tagcgtacta atacatcttc agatacttgt
    42901 aaagcttctc cttcagataa atctacgcga tagaaagggc ctttgccttt actgattctc
    42961 gtaacggtta acataaacat cctcctcgaa catatattct ctatcatacc acagaaaatc
    43021 cccgtaatca ggtattatat gttagaataa accacagaaa aaagaaaaag ggagatactt
    43081 atggcagaaa caattgtcaa aactggacaa acggttcctt tgaaaatcaa gcgtttaggc
    43141 ataaatggtg aaggaatcgg ttatttcaaa cggttgatca tatttgttcc atatgcacta
    43201 ccaaaagaag aagtactagt gaaaatcacg aaagcaactc ctcgctatgc agaaggagaa
    43261 ttaataaaag tcaaaaaaac aagcaaagat cgcgtagtgg caccatgtcc tgtttactat
    43321 gaatgcggtg gctgtcaatt acaacactta gcttatcaag ctcaattgga ttttaaaaag
    43381 gatctgcttt tgcaagcatt ggaaaaattc aaaccagcag gctttcgatc ttatcaactt
    43441 ttgccgacga tcgggatgga tgagccttgg cattatagaa acaaagcaca atttcagtta
    43501 cgaaaaaata agcagactca aaaaattgaa gctggtttat acgaagcaaa ctctcatcag
    43561 ttagtcccta taacagactg cttggttcaa gaacctcgaa cacaaaaagt aatgaatact
    43621 gttgttcaac tattgaataa atttgatgca cccatctatg atgaacggac aaacagtgga
    43681 atcttccgca caatcatggt tagaatcggt gttaaaactg gggagttaca agttgttttt
    43741 attactcgca gtaaaaaatt cccgcaaaaa aacgcaatga tccgtgagat caatgaacga
    43801 ctgcccgaag ttgtttcaat catgcaaaat gtccaggcac aaaaaacgtc tctcgtgatg
    43861 ggggatgaaa cgatccactt atggggaaaa gaagccattg aagaacaaat caatgaagtg
    43921 actttcgatc tttctcctcg tgccttcttt caactcaatc ctcagcagac cgaattgctt
    43981 tatggcgaag gaatcaaagc attagatgtc cagcctaatg aaacgatcgt ggatgcttat
    44041 tgcggagttg ggacgatcgg cttaagtgta gcaaaacaag ccaaagaagt acggggaatg
    44101 gataccgttc ctcaagcaat cgctgatgca aaaaaaaatg cggaaagatt aggatatcac
    44161 aacactcgat atgaagtcgg gacagcagag caagttctgc ctaaatggtt gaatgaaggt
    44221 tttcagcctg atggtatcat cgtagatcca ccacgtacgg gtttggataa cgcattgatc
    44281 caatcattat tgaaataccc tccaaaaaaa cttgtttata tctcctgtaa tgtttctaca
    44341 cttgccagag atctggttaa tttaagtaaa aagttcaaga ttgaatattt acagtccgtc
    44401 gacatgtttc ctcagactgc acgttgtgaa gttgtcgtga agatgacgag actcgctgac
    44461 taaatgaaag aggttgtgaa aaagtctgcc ctgtatcaag taataagaac agccaaacaa
    44521 aaatagctct tcatgtttta tgaatactgt acttgtgacc gaagagttaa caggaggaca
    44581 ctatttattt aaaaaaaggg ttgtgacata gtttttgtca cagccctttt tgattattat
    44641 tggatattca cgtctatcac ttgataaaat gcatttgtcg tatcgctgat attccatact
    44701 gctaaaatca cattatatcc ttttcgatcc tgcggaagtg tgatcgtttg gttgactgtt
    44761 tttggtggaa cagttgcttt gtcgtctatt tttgtgatca attcaaaatc actaaatttc
    44821 aaaggttgat taggattcca agttggtttg gtaatgtagt aatcccaagt acttgtccga
    44881 tgttgtgctg ttaaattcca agtaatattt aatgttcctg gattaaccat gtttttatgc
    44941 catctgttag atgtctgttc atctaaaggc tcaaagccgc tgactcctgc actagcaatt
    45001 tttccatcaa tgaatgtatt tttggtagct tcgatacttt gcggttccca ttgtgctctt
    45061 ccgacatttt gatttaagtt tcctgctgct gatgttccta ggtatgcacg gcttcctgga
    45121 gaagtaatat aaccatgcgc aaaacctgga atgctaaaac cgaacaaccc taaactaact
    45181 aacccaataa acaataacgt actaatcttt ttcatgtaga aacctccttc atttgataac
    45241 cacattgtaa acgctttatt gtattaacac aaacattatg cttttataat tttatgttga
    45301 agtaaaaaag gtgaaaaaag taagatgcag attataacag aagtagacga gaaaagtaca
    45361 aatagaaaac atgagaatca aatcatatga tctttttcaa aaacatcatt catataaaca
    45421 aatgttcaac tttttaataa caacaattat caattttttt cttacttcac aaactaaata
    45481 caggtcttgc tgtgagcctt catggtaaac taatattata gaaaggagtt agtaaaatga
    45541 agatgataaa agatattcgt ttttgggttt gtgttatagg aattgtcata ttaggctttt
    45601 tatcagggtt gcttagcgga aatcccggaa aatattacta ttctttgcaa cttccaccat
    45661 ttgcaccacc tagctggata tttgggccga tgtggacctt actgtatata ttgatgggta
    45721 tttctcttta tttgttactt aatcacaaca acaaaaaaca gcgaaacaat cttgtcggtc
    45781 tttttgtgat tcagttcatt tttaatttta tatggtctgc tctatttttt aatttaagaa
    45841 atattttcat tgcagcaatc gatattacac ttttagttat tttcttgtca gtgcttatgt
    45901 atcagttgtg gctgcatcat cgcctggcaa tgtggctcat gattccttat tatttatggg
    45961 tactattcgc aactctattg aattattcaa tttatttttt aaactaagcg ctaaaaagag
    46021 acgtcctgta atttaacaca tagaaaaagt gccacctaag ttagattttt tgtctaattt
    46081 aggtggcact ctttattaac caaactattt ttttctagta cccacttgtt gttccatact
    46141 cattattctg gtcataacca taaccatttt gttcctgtcc agcgtaagga tcataacttt
    46201 gagtatcttg acttggtgta tagtactgac ttgtatcttc tgtttgctga taataggtat
    46261 tcggatcttg gtactgatca tatgtgtttt ctgaatagga agaataatcg gtgtaccctt
    46321 cactattcga tccatcaccg tttgtcgaat cgccatcttc cgaatcatca aagaacatca
    46381 ttgaagcatt ctcatttttc aaattaggta atgtatcgct tgtttttata tttaattgtt
    46441 tcttcagttc attttggatc gaaagaagat cattttttcc taaaatttga tagtagatat
    46501 cattgatcat ttgtccttcg ccttgcaact ggtcttgttt gattgtttca aacgccgggg
    46561 tgtagttcgt cgctacatca agcatgtcat cccaatctaa gtccgtcgtc acattgttct
    46621 caactgcttt taaaattttt ctataattgc ttacgccatc taaacttaaa actttattga
    46681 cgattttcgt cactacttcc cgctgacgac gttgtcgacc gatatcgcct tctggatctt
    46741 cgtgtcgcat tcgagaatag gctaaacctt tttctccatt caatgtttgt tcacctactg
    46801 gtacatggac accatccaaa gtaaagtcaa ttttattatt cactttgatg ccaccgaccg
    46861 cattgatcaa atcttccatg ccatccaaat tgatcgttac ataatgatca ataggaatat
    46921 cgagcagttg ctcaattgaa tccatggcca tttcgacacc accaaatgcg taggcatgat
    46981 ttaatttatc taccgttcca taacctacga tattcgtata aatatctcgg tccaaactga
    47041 tgatcgttga ttttttttgt ttcggattaa ctgttactac catcatcgta tcagaacgtc
    47101 cttgttccgt tcttcctaat ccaccggtat ctaaacctaa tagcaaaacc gaaaaaggtt
    47161 ctttgtcatc aatgcttact ctctcagaac gtttggagga tattcgatta gagtttttag
    47221 aaattttgtt tactgtttgg ctcgcttctc ccataaatct gattccgtat gctgataatc
    47281 cggcaatcag caaaacgaat acccctaaca aggttaatag aactttttgc catcgcttca
    47341 taatacacct ctgtttcaca ttttctaaaa tattgtctca tataactgtt caatcagcaa
    47401 attcactttt taatcataag aaaactttaa aaaacatttt tgtgtaacga ttattatttt
    47461 ttaaaatttc tcaaaattct taactatcat accataccgt gaaaaagatc gaaagaccga
    47521 atacacgcag ttcgcaatcg ttttatcttt ttttatgtat tttttccaga aaaagcgaac
    47581 aacaaggtat tttccaaata atcgtgcagt aaaatgatcg cacatacctt tcccatcttt
    47641 ttaacagtct ttgcctaccg ttcagattat cattcgattt cacgacaatt tcttcctatg
    47701 actggtcctt ttgttaaacc catcttctat tcgttttatt tccagctcac tgcatggctc
    47761 ttaaaatgac tcgaactagt gattgcatta ccatcatctt ttaatggata gatatgctcc
    47821 tcttcaaagt aaaacgattt tcttttaaag taatagaatt gacatggtaa tgagtatgta
    47881 tactagtggt ttcacaaatg gtcttttatt caacatccaa aaactgaaat ttctttaaaa
    47941 tccattacta acgaagaaaa tgttccttgc ttgataatta gttaggacat gtcaagtgaa
    48001 caaatgcatt tacttagcca aaaaatctaa aaacttcata aatagacaaa aagacacgac
    48061 tctctaagaa gtcgtgtctt tattcaacaa attattataa tttagtcact tcagcagctt
    48121 gaggtccgcg tgcaccttca acaatcgtga attctacttc ttgaccttct tctaggctct
    48181 tgaagccgtc tccttgaatt gctgagaaat gaacaaatac gtcatctccg ccgtctactg
    48241 taataaaccc aaatcctttt tcattgttga accatttaac cgttccgtgt tccataaatg
    48301 tatatcctcc aaaaaagttc ttgcaagtaa ccttgcaaga acattatacc caatttagaa
    48361 aacgctagca agctttcgct cttttatttt ccaaattatt tttaagactg atatgacgga
    48421 ggaaatggtt attttgctgc ttcgaaacgt ttgtttactt catcccaatt aataacattc
    48481 cagaatgctg caatataatc tggtcggaca tttttatatt tcaaataata agcatgttcc
    48541 caaacgtcca aacctagaat tggtgtcttt ccttccatca atggagaatc ttgatttgca
    48601 gtagaggtaa tagctaattt tccattttcc attacaagcc aagcccatcc agaaccaaat
    48661 cgtccagcgg ctgctttttt gaattcttct ttaaaagaag aaaaatcacc aaaagcttca
    48721 ttaatcgctt cttttatttc tcctgtaggt tcgccaccag catttggtgc catgatttcc
    48781 cagaaaaatg aatggttagc atgtccgcca ccattgttac gtacagctgt cttgatatct
    48841 gttggaatag cgtccatatc agataataat tcttctattg ttttttcgcc taattctggg
    48901 tatttctcaa ttgctgaatt taaattcgtc acataagtat tgtgatgctt atcatgatgc
    48961 agatgcatcg tttcttcgtc aatataaggt tccaatgcgt catatgcata aggtagatct
    49021 ggtaatgtgt aagtcataaa aaaattcctc ctcaatgttt tcttaataat gtctacatta
    49081 caaagagtaa caaagagaag gaaattcttc aattgttatg cctagtcgtc tttttcactt
    49141 tgacctactt cttcttcaaa aacctcagtt tctttaaaaa taaacaactt gctgaaaata
    49201 tagttcgcaa ggataacaat aatttgagtg atgattttcg ccacatactc attgctgttc
    49261 ataacattga tcaacaatac cattgccccc atgtccaatc cgtaagaaag gatacggtag
    49321 aagaagaact taccgcattc aataagtgca tgtgtaaaat tcggtgattt tgaatggaat
    49381 acccaaagtt tgttcgttac aaaagcaaac aatacagaac aaaaccacga aatagaattg
    49441 gataaggcca tacttaaatc aaaatattgg cgtgcgagag caaaactaac aaaatttaca
    49501 atcgtagcca aaccaccaaa aaagagatag actagtatct cccaatatcc ttttgcttct
    49561 aaatatcctt ttaactgtcg atactgcttc atgagccaac ctaccttatt aaaaattctt
    49621 atttatcata ctctatattt caataacttt catctttatt taaaaaaatt aatttttttt
    49681 gatcctttgc ctttgtctct gcttggatcg tcacatgtgt aataccatat tttaatttta
    49741 ataaagaaat tatacgagga tatatctttt caatctcgct tagtagctga tcttcaaaat
    49801 caatatgtcc gtcgaaaata attatctttt cgctatactg ccaaatatgg acatgatgaa
    49861 catcctttac cccatcgatt gcttcaattt cttgttccat tttttcatag tcgatagcag
    49921 gtgcactttg tatcaaaata gcggcagctt ttttgatcac cattatcgct tctatcaata
    49981 tatatatcga aatgatcagt gtaataactg gatcgatcca gtagatatcg aaaaaacgga
    50041 tcaaaattgc tccgataatc acacttaccg aagacagtgt atcacttaac aaatgcaaat
    50101 aactagattt tatattcaaa ctttcatctg cttcttgtcg taataataat actgagaaca
    50161 aattcgcgag caatccaata actgctactg ttagcatcaa atgactattt atcttttctg
    50221 gtgaagtgaa ccgcttgaat gcttcaacgg ttaaaaacaa ggataatatg atcaatatga
    50281 atgagttgat gaaagcactc aatatttcta aacgctggta gccatacgta cgttttttat
    50341 ttgcttcttt tcgggccatt ttttgtgccc cgtaagaaaa aataattgcc aatgtatcac
    50401 taaggttatg gaaagcatct gaaacaagag acaaactccc tgacataatc cctccaataa
    50461 attctgataa agtgatcacc gcattcaaaa ccactactcc aaatagtttt tttgatgatc
    50521 tctgtggctg tgtaggcact attccttcct ccattttatt tatattggat agtctttaga
    50581 caagaataac atttttttga tatttcacca atcattcagc tgtttcctta aagcacttgt
    50641 atttcacttg atacttcgct agaattgcaa gtgatgacac tactagatga ggagtactta
    50701 tgacaacaaa acaattaatt atcagttcct ttatacgatt caaagaccta aaggaggcga
    50761 gaaatgtccc attttggaaa gccattgtct atcttttagt tttgagtata attatggctt
    50821 tgccaatctc ttttcaagtt tttcaagtct taaacaacat tcaattggat gggcaaaaga
    50881 ttgctactcg cattcctgat tttacaatcc aaaacgggca gcttcaaacc gaagaaaaag
    50941 aaggattcat ttaccaaaca aactccatta tcttcacatt tgatccagag ggaaaacgaa
    51001 cagaacagga catctctact gatttgatgg ggaattttgt tagtgtcggg atgttaaaaa
    51061 acaaacttat catagctctt cctaatacag gcacgacttc tgctttgttg aacaataacc
    51121 aattagaact tccctacacc aatgaatctt taaaaaactt aacaggtaag cagctccgtt
    51181 cttttttaag tgaagcatct ataccacttt ggataaaagt cctgacattt atattttcta
    51241 tttatcctag ttttctgaat ctgctgatca ctttgctatt taccaacatt gctgcttttc
    51301 tctatgcacg ctttcgacta acaaaagcta cttttcttga ttgtttaaaa acattgatct
    51361 attcaatttc attgcctact ataattgcaa caatcttgat ggtctttctt ccttcttttg
    51421 acactagcgc cttcattgct tttgcaggaa tctttatttt tgctcaagct gtcaaaggat
    51481 gggcaaaaat atcgatcaat taagaaataa agacaactcg ttatttctac ttcaatagac
    51541 ccttttagag gttgtgacat ttttttgtca cagccccttt tttatttgaa aaatatttct
    51601 ttctcaaaaa acaagcaagg cgcttcaaag ttcttcttgt atgcgctaca cttagagtaa
    51661 agaaaggcgg gaaattaact atgtcagaaa gaatcattta tgcagatcgt ccatttcgtg
    51721 atgaatttat cgaagaaatc catactatag cgcctggtta tatctttaaa acagaattac
    51781 aaccagagga tctacaaaat gtagagatca gtttgggctg gaactcagac taccaagaaa
    51841 aactattagc ctcttctacc ttgaaatggg tccaatctat ctcagctggt gttgatcagc
    51901 taccccttga gactttttca aagaaacata ttttactttc aaatggtagt ggcatccaca
    51961 gtgaatcgat tacggagcat gtcttaggaa tcatccttgg gtattctcgt ggtctttttc
    52021 aagcacaaaa ggcacagagt gacatgaaat ggttaggttc atcggtccat taccaatcta
    52081 tccaagggaa aaaaatacta atcattggaa ctggccatat tggaaaaatg attgcaaaaa
    52141 aatgcaaagc attagacatg aactgctatg gaatcaatac atccggtcat ccagcagaag
    52201 gaatggaaaa gactttttct ttaaatcaac taaaggaagt tcttcctgaa gtagatttcg
    52261 tagtcaatat cttacctcta acggaggaaa caactgggct ctttgatcag catatgtttg
    52321 aacactttga tccaaaatct gtattcatca atgttggccg tggtgcttct gttaagacac
    52381 aagatctggt gcaggcttta aataaccagc aactttcctt tgcagcatta gacgtttttg
    52441 aggaagagcc tcttccacaa gatcatcctc tttggaaaat ggacaatgta ctgattactt
    52501 cccacattgc aggtttgaca cctgattttc aaaagaaatt aatggctatt tttttaacca
    52561 atctgaaaag ctactttgcc acccatgagc ttcaaaccaa tcaagtaaaa ttgtctgcag
    52621 gatattaata gctgaaaaca atattttcaa aagaaaaaag agaaggtgac aaaaattgtg
    52681 tcaccctctc tttttttatt gttttttaaa gtgataggtt ggctcctcca ggttgggatt
    52741 ataatcaaca agtaaatcat atcctttaaa gaaccattca tctgcttcct cgataaaaaa
    52801 aagtgtccca tcaatttcca ctttctttac aggatgttct ggctgttcaa ctgacattcc
    52861 aatcgaaaaa ccatcatgaa cctctgtttt gccgtagact tttccaaaaa aacgtattcc
    52921 gtaagtttct ggcagatcaa tttctgagtc aaaccacttt tgtgcttttg gcgttaccgt
    52981 taatttcatc ccaacaacct actttctctt ttctttctat tgattcatct tatcgtctag
    53041 aatatccaca tcgcctgtct ctccaataac cagtagatta tcattttcac gaacatattc
    53101 atctgctgca ggagaagcga taaccgtttg atctactctt cgtatggcga ctactgttaa
    53161 gtcaaaacgt tgcctgaaat ttaattcagc taatgttttg ttgaaaaatt taggattgga
    53221 gactcggatt tctgctaaag aatatttatc tgacaactct aggtaatcta aaatattctt
    53281 tgacactaaa ttatgcgcaa tccttattcc catgtctcgc tcgggatgga cgacgcgatc
    53341 agctccgatc ttttcaagta ctctggcatg atactcattt tgggcttttg ctaaaatatt
    53401 tggtacgccc atttccttta ccatcagagt aactaagata ctggcttgaa tatcttctcc
    53461 aatagcgaca attacatgat cgaaatttct tatgcctaat gatcgaagtg tcatttcatc
    53521 ctgtgcattt gccacaacag catgagtggc tatattcata tattcattga cccgatcttc
    53581 attactatca atagccagta cttcttgacc agcttcgatc agtgttcggc agatacttcc
    53641 gccaaatcgt ccaagaccta caattgcaaa attttgtttc accgttttcc tcctttagta
    53701 tcttcttttc tcagtataac aaagccttta caaaaacaaa agcaagcatc attattgtaa
    53761 aaaagccaag aaaaataata gttattttct cagcttttga ttatcctctt tatcatcgtt
    53821 tttatttcac caaaccatgt ttgaatgcat agatagcggc ttgtgtacgg tcttccactt
    53881 ctagcttagc caatatattg gaaacatgtg tttttactgt tttcagtgta ataaacaatt
    53941 cgtccgctat ttcctgatta ctttttcctt cagaaatcag cattaaaatt tcattttccc
    54001 gattcgttag ttcttcatgt aatacaggct catttcgccg actcattttt tccatcattt
    54061 ttgttgtcac ttctggttct aatactcgct cgccacgttg cgttgccctt atagcatcag
    54121 caatttcatg tgcggtagag gtcttcaaca aataccctgc tgcacctgct tcaatggcag
    54181 gataaacttt ttcgtcatca ataaaactgg ttacgataat gattttagct tctggccaat
    54241 cttttaagat tgcttttgtt gattcgatac catccatttc ttccatgact aagtccatta
    54301 aaatgacgtc cggtcgaagt gtcatcgcct tctcatagcc ttgtcgtcca ttttcagctt
    54361 ctccaattac ttcaatgtct tcttgaatag ataaataaaa agagacgcct aagcgcacca
    54421 tttcatggtc atctactaat aaaactttta tcatccttat ctatgcctcc ttcatcaaag
    54481 ggaccttgat ttctacactt gtaccttgac ctttaaaact aatgattttt actgttccac
    54541 caataccagc tactcgttct ttgatattgt tcaatccata acttcccgtt ttcgtttcat
    54601 tcatattaaa ccctgttccg tcgtcaataa tacgtaacaa aagattattg tctattttgt
    54661 gcaaatatac ctctaattca ttggctttag catgtcttaa tgtatttgat aacaattctt
    54721 gaacgattcg gaacaagtga tcctcaatgg aactagatag ttttacatct tctacatccc
    54781 atttcagcga aatctggatt ttattttgca attccttcaa taactgctcg ataccttgct
    54841 ttaaactttt ctcttctaaa ttgactggac gtagatgaag aagcagcgca cgcatctcag
    54901 actgggaagc gttgatgatc tctgctacca ttttcaactg cttgcgaaac atttctggtg
    54961 tctcgctttt ttctgcttgc tccgtcaatg ccgacatcat catcattgct gcaaacaatt
    55021 gttgcgaaac tgaatcatgc agctcacggg ctaatcgatg tctttctaat tctaaaattt
    55081 cttctttggt ttgtccatct acatattggg gacggctcgt tacaatttgt aattcactag
    55141 atacttcaat cattttttct tttatcttag tgatttcctt atcaatatct ttgatgtata
    55201 aatcgtccga tgcacttggg atcggaagaa gcaacaattt ggattcataa ttgccagaag
    55261 aaagtgcacg cagcttttct tcgattttcc cgtattttgt cttttgaata agtgataata
    55321 atagaaagac aattaatcct acacctaagg aaatggctaa caaatggaag ataagcggaa
    55381 catataataa acgtgcacgc agtaattctc cccaccaatg actttgattg ctggcataaa
    55441 aataagtgaa aagtgaaaat agaataataa ggaaagccgc aatccccgaa taaacagcta
    55501 gcatcgctct ggatattttt cccatcatat tcgtatcacc tcgacatctc caatcaaggt
    55561 attagtaata atcttcaatc tacgagggtt ttcatcataa tcactgctgt agattttgat
    55621 ttgttcattt ttcaaagaaa attgctcttc ttcaaacaag acatttccta ctaatgtcgc
    55681 atgctctaat cggatggcta cgcccaaagg tactaagatc cgtgttctgc ctatcccttt
    55741 tcttacaatc acaatattat catcttttgg caaaagcgta ttgcccaaat ctatgatagt
    55801 atcaccagaa atgacggcga tgttgatatc gtcccattca tagacgtcgt ttccaatacg
    55861 ttggttaccg aataattgct gtcttttccg ctcattatta tgtgttttta attgctctgt
    55921 ttggatcatc atgatctgtt tctttcgcca aaaagcattt ttggttaaat ctatccctga
    55981 aatctctaca cctttcagac caataaataa aacggcaaat acagccatca tccataaagc
    56041 aggactgttg actaagctaa aaaaaatgac caaacttcct aatatcaatt gaaaattttg
    56101 aaatttagta cgaggatgtt tgcgcatagc tagatatata ttgaaaatac cgaatatcac
    56161 taaaagcaaa agtccagtat tgtttacgat ttgccaaaca gcaaataaca gcagtagtgc
    56221 ttcaactacc acaaaaaaac gccaagaact attcatcgct ctttctccct cctgacacat
    56281 tctcatttca tcatacctat ttttttaact gttggctata ggactttaga tgtaagatcg
    56341 tttgttgaaa tctaaaatac acaaagagaa aaagatctag agtgtatcat cagtaagatg
    56401 aactctctag atctttcagt cagactacgc ttgttctact ttgacgattt taactaacat
    56461 atcgccacct ggagtagcaa tagttacttc atcattttta cgtttgccaa tcaatgcttg
    56521 cgcaatagga gaatcattgg aaattttgcc agaaaacgga tctgcttcag cgcttccgac
    56581 aatcgtgtac tcttcttctt ctccatctgg tagttcgatg aatgtaactg ttttaccaat
    56641 tgatacctca tctgcatcta caccgtcgtt atcgatgatt tgagcaaaac gaatcatatt
    56701 ttcaattgtt gtgattcttc cttcaacaaa tgcttgttca tctttcgctg attcatattc
    56761 agagttttcg gaaagatctc cgaaaccgcg ggcaattttg attcgttcaa tgatttctcc
    56821 gcgtttgact gtttttagtt cttctaattc tttttctaat ttttctttac cttctagagt
    56881 cattggataa actttctcta ccatgtgtaa cgtctccttt tttcgataaa ataccgcaaa
    56941 aggtaatctt ttgaggaata tagtccaaaa aagattacca cgcttttctt caaatgtaaa
    57001 tgtttttcta aaaatgatca atgtctagag cctgtttttc taagaattat ttacatattt
    57061 ttccactaat tccatatgtt cttcataagt tttagcgaaa taaacatttc cagtgctcgt
    57121 atctgctacg aaataataat agtcattttc tgctggttct aatactgcct tgattgcctc
    57181 ttcgcttgga ttgtcaaaag gtccaggtcc atagccggta ttggtataca aattatatgg
    57241 tgaatctaca gctgtatctt catacgtcac taattctttg tgttcaccta atgcgtataa
    57301 aacagagata tctgactgaa gtggcatatt tgctttgatt cggttaaaga agacttgtgc
    57361 aatgttttta cgatcatttt cttttacgcc ttctttttca actagagaag ctagagttaa
    57421 aacttcttgt acagtcaaat ttttctgctt gatagctgaa taatagtttt gcatgaccgt
    57481 attcgtcttg ttcaccattt caatcactag atccttaagc gaagtactcg tgtaataatc
    57541 atatgtggct gggaataagt aaccttccaa acggtatttt gtgttctcag ctttagatgc
    57601 actttccaac agttctggga atttttggtg caactcgtta aagaaagtct catcattcac
    57661 taaatctaaa aattctttct tgtctttacc agttaccttc gctacccgtt cagcaatctg
    57721 atcgatatcg tacccttctg gaatggcaat tttcccatct gcaacttttg ttggctcaga
    57781 agtaccgcct tcttgcaact gtttgccaat ctcgtcaaga gtcatattag gcgctaactg
    57841 ataatagcca gcttgaaagc cagttaaatt tttaaatttt gtataataat tgaaaacaat
    57901 cccgctttta ataatattgt ccttctccaa aatctcacca atctgcttgt tagaagagcc
    57961 actcgggatc tcgacttgga ctaattggtc atctgattta tctaaaggct tcaacccgct
    58021 atctacataa cgatacacgg taaatccaag aaatccgcca ataatcaata atgtaagagc
    58081 aatcactaaa atgatcttcc tcacaatctt atcttctttt ttacgcagat ttctccgctt
    58141 gtcgattata tctgctgtag ctgccttact ggcttctttt ttatctttac ttgggtgttg
    58201 tttgtttcct gacaaaacaa ctcctcctta ctatcaagtt cgtaacttta ttcattatac
    58261 atgatatttg aattggcgtg aatgatttta tttaaatatt ctatcaaaaa tgtaagtagt
    58321 aaatccatta ctataagatt aaaataaatg ttatcaagat acaagctatt ttagctttat
    58381 tctttctgta aaaaagaaag gagactaaat aaactattat gaaaaaagga aaacatgcta
    58441 aaaaaagaaa atattcattt ttaatgatcg ttgtcgtgtt gtttagcctt agtgcgttct
    58501 ctacaggaac tattcttgga tggcaatttt acaataatga acactctcag atagttgccc
    58561 atgctcaatc agctcaaaaa aagttgatac tgactaccaa tgaacaacag ctcgttgaaa
    58621 aaatcgatca actattaaga aaaaatgatt atattggctc aatttacgta aagaaaaata
    58681 atcgcatcat catggaaaaa ggctatggct atgcgaataa actcacgcaa caaccaaatg
    58741 atccttctct ttattatcag attggttcgg ttcaaaaagc attgactact cttttgattt
    58801 taaaacaagt cgagcgtggg cacctttctt tagatactaa gctggctcaa ttctatccac
    58861 aaattgctgg cagccagcaa attactatcc gtgacttgct gtatatgcgc tcaggcttgc
    58921 accgaactgc ttctccaacc ataccgatga ctgatgaaga agtcgttcaa tttgcgattc
    58981 agcacttaaa atttacagat tatcagacct ctcattatga ttcattgaac tttaccatat
    59041 tgactggaat tttgatcaaa ttaacaaatc aaccgtatga aaaattattg accgatgata
    59101 tcatcgaacc tttaggatta cagcatacaa aattttatga ccaagtcaaa aattcatcca
    59161 atcatgcact atcctatcaa atgtctaaag aggatgatta ctttaaacca ctgacagaat
    59221 ctgaaacaga gatccataac gaattaggga ctggtaatat cagtatgtcc gtctatgatt
    59281 taaatacgct gtttacacaa gttttatctg gaaaactagt ttccaaagac ttactcttct
    59341 cattatggcg tgaaaatgcg aatggacatc catatagtgg tggggtatat agcggagata
    59401 attatatcct gtcgcaagga aatatcgact cttttgatac atctgctata tttagcaaag
    59461 attcacagga tgctatcatc atggaaagca atataaaagc tgacaaaact atcaaactgc
    59521 ctactgctga tctaagaaac caaatctatg acctgatgga aggaactact aagttggcaa
    59581 atagctgata tgatgaaaag atagcaaata ctacttcttt gaatagcatt tgcttaaaaa
    59641 aagtactcga ctaaacgtag gaaagagtgt gggacaaatc taaaaatcaa tttttgctac
    59701 agactttaat tccaaataaa cagaacagaa agaggtgttc ttctttctgt tctgtccaaa
    59761 ttattctaag atttctcttt accaacatta tttgacaaag ggcctattaa atctaaaata
    59821 gtatctttag attgctaaaa tatgtgctag caaatcattc atggcttgtt cttattttta
    59881 attttatgca ataaaaaaga agaacaatta gcgtgattat agaaataaat aatgagattt
    59941 tagaaaaaaa tgtgtatgaa tacctgattg ttactttatt tattccactt tcacttttta
    60001 ctgtaacaaa aggacctcct tgttttagta ctgtagcatt ttttgaatta acagtaaccg
    60061 ttaatccttt ataccggaat acaggtaaaa ctattgtttt gccttttgaa gatttaaacg
    60121 taaatgtaat ttcatcttta tttggagaaa agctactata aataacttga ccatcttctg
    60181 taacttgatg gtttttcaaa agcaattgat cttttttata gcctataggt acataatcaa
    60241 aattctcaaa ttcttcaagt ttattttcca tttgttcatt agaataagtt ccttgaaaat
    60301 tcat
//
LOCUS       DADVXE010000011        57791 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.011, whole genome shotgun sequence.
ACCESSION   DADVXE010000011 DADVXE010000000
VERSION     DADVXE010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 57791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.011"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            86..1603
                     /locus_tag="KB913_000717"
     CDS             86..1603
                     /locus_tag="KB913_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBB6819103.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            1575..2864
                     /locus_tag="KB913_000718"
     CDS             1575..2864
                     /locus_tag="KB913_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6819104.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            3039..3935
                     /locus_tag="KB913_000719"
     CDS             3039..3935
                     /locus_tag="KB913_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6819105.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            3949..4812
                     /locus_tag="KB913_000720"
     CDS             3949..4812
                     /locus_tag="KB913_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6819106.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            4818..5381
                     /locus_tag="KB913_000721"
     CDS             4818..5381
                     /locus_tag="KB913_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBB6819107.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            5403..6914
                     /locus_tag="KB913_000722"
     CDS             5403..6914
                     /locus_tag="KB913_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBB6819108.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            6926..7885
                     /locus_tag="KB913_000723"
     CDS             6926..7885
                     /locus_tag="KB913_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBB6819109.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSKKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            7971..9050
                     /locus_tag="KB913_000724"
     CDS             7971..9050
                     /locus_tag="KB913_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6819110.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(9302..10702)
                     /locus_tag="KB913_000725"
     CDS             complement(9302..10702)
                     /locus_tag="KB913_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBB6819111.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            10920..12581
                     /locus_tag="KB913_000726"
     CDS             10920..12581
                     /locus_tag="KB913_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBB6819112.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            12538..13236
                     /locus_tag="KB913_000727"
     CDS             12538..13236
                     /locus_tag="KB913_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBB6819113.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            13252..14676
                     /gene="araA"
                     /locus_tag="KB913_000728"
     CDS             13252..14676
                     /gene="araA"
                     /locus_tag="KB913_000728"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBB6819114.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            14983..16143
                     /locus_tag="KB913_000729"
     CDS             14983..16143
                     /locus_tag="KB913_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBB6819115.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            16261..18120
                     /locus_tag="KB913_000730"
     CDS             16261..18120
                     /locus_tag="KB913_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6819116.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            18230..18664
                     /locus_tag="KB913_000731"
     CDS             18230..18664
                     /locus_tag="KB913_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819117.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(18923..19084)
                     /locus_tag="KB913_000732"
     CDS             complement(18923..19084)
                     /locus_tag="KB913_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819118.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(19103..20125)
                     /locus_tag="KB913_000733"
     CDS             complement(19103..20125)
                     /locus_tag="KB913_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBB6819119.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            20253..20606
                     /locus_tag="KB913_000734"
     CDS             20253..20606
                     /locus_tag="KB913_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBB6819120.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20618..21784
                     /locus_tag="KB913_000735"
     CDS             20618..21784
                     /locus_tag="KB913_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6819121.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(21876..22496)
                     /locus_tag="KB913_000736"
     CDS             complement(21876..22496)
                     /locus_tag="KB913_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBB6819122.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(22688..22984)
                     /locus_tag="KB913_000737"
     CDS             complement(22688..22984)
                     /locus_tag="KB913_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6819123.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            23188..23838
                     /locus_tag="KB913_000738"
     CDS             23188..23838
                     /locus_tag="KB913_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBB6819124.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            23854..25581
                     /locus_tag="KB913_000739"
     CDS             23854..25581
                     /locus_tag="KB913_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6819125.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            25578..27470
                     /locus_tag="KB913_000740"
     CDS             25578..27470
                     /locus_tag="KB913_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6819126.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            28174..29043
                     /locus_tag="KB913_000741"
     CDS             28174..29043
                     /locus_tag="KB913_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBB6819127.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            29252..30277
                     /locus_tag="KB913_000742"
     CDS             29252..30277
                     /locus_tag="KB913_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBB6819128.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            30316..31266
                     /gene="manA"
                     /locus_tag="KB913_000743"
     CDS             30316..31266
                     /gene="manA"
                     /locus_tag="KB913_000743"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBB6819129.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            31360..33063
                     /locus_tag="KB913_000744"
     CDS             31360..33063
                     /locus_tag="KB913_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6819130.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            33065..35098
                     /locus_tag="KB913_000745"
     CDS             33065..35098
                     /locus_tag="KB913_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6819131.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            35109..35549
                     /locus_tag="KB913_000746"
     CDS             35109..35549
                     /locus_tag="KB913_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6819132.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(35749..36876)
                     /locus_tag="KB913_000747"
     CDS             complement(35749..36876)
                     /locus_tag="KB913_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6819133.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(36879..37556)
                     /locus_tag="KB913_000748"
     CDS             complement(36879..37556)
                     /locus_tag="KB913_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6819134.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            37820..39586
                     /locus_tag="KB913_000749"
     CDS             37820..39586
                     /locus_tag="KB913_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBB6819135.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            39601..40038
                     /locus_tag="KB913_000750"
     CDS             39601..40038
                     /locus_tag="KB913_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6819136.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            40051..41202
                     /locus_tag="KB913_000751"
     CDS             40051..41202
                     /locus_tag="KB913_000751"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBB6819137.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(41264..41962)
                     /locus_tag="KB913_000752"
     CDS             complement(41264..41962)
                     /locus_tag="KB913_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBB6819138.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(41955..43307)
                     /locus_tag="KB913_000753"
     CDS             complement(41955..43307)
                     /locus_tag="KB913_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBB6819139.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(43530..44930)
                     /locus_tag="KB913_000754"
     CDS             complement(43530..44930)
                     /locus_tag="KB913_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBB6819140.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            45091..45828
                     /locus_tag="KB913_000755"
     CDS             45091..45828
                     /locus_tag="KB913_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBB6819141.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            45953..46432
                     /locus_tag="KB913_000756"
     CDS             45953..46432
                     /locus_tag="KB913_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBB6819142.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            46429..47196
                     /locus_tag="KB913_000757"
     CDS             46429..47196
                     /locus_tag="KB913_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819143.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            47426..47995
                     /gene="lepB"
                     /locus_tag="KB913_000758"
     CDS             47426..47995
                     /gene="lepB"
                     /locus_tag="KB913_000758"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6819144.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(48099..48701)
                     /locus_tag="KB913_000759"
     CDS             complement(48099..48701)
                     /locus_tag="KB913_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6819145.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            48807..49276
                     /locus_tag="KB913_000760"
                     /pseudo
     CDS             48807..49276
                     /locus_tag="KB913_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            49382..49966
                     /locus_tag="KB913_000761"
     CDS             49382..49966
                     /locus_tag="KB913_000761"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBB6819146.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            49969..51042
                     /gene="prfA"
                     /locus_tag="KB913_000762"
     CDS             49969..51042
                     /gene="prfA"
                     /locus_tag="KB913_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBB6819147.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            51035..51874
                     /gene="prmC"
                     /locus_tag="KB913_000763"
     CDS             51035..51874
                     /gene="prmC"
                     /locus_tag="KB913_000763"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBB6819148.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            51867..52046
                     /locus_tag="KB913_000764"
     CDS             51867..52046
                     /locus_tag="KB913_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819149.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            52068..53093
                     /locus_tag="KB913_000765"
     CDS             52068..53093
                     /locus_tag="KB913_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBB6819150.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            53284..54528
                     /locus_tag="KB913_000766"
     CDS             53284..54528
                     /locus_tag="KB913_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBB6819151.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            54681..55628
                     /locus_tag="KB913_000767"
     CDS             54681..55628
                     /locus_tag="KB913_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6819152.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            55762..56391
                     /gene="upp"
                     /locus_tag="KB913_000768"
     CDS             55762..56391
                     /gene="upp"
                     /locus_tag="KB913_000768"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBB6819153.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(56530..56772)
                     /locus_tag="KB913_000769"
     CDS             complement(56530..56772)
                     /locus_tag="KB913_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819154.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            56893..56965
                     /locus_tag="KB913_000770"
     tRNA            56893..56965
                     /locus_tag="KB913_000770"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:56926..56928,aa:Thr,seq:cgt)
     gene            complement(57084..57722)
                     /locus_tag="KB913_000771"
     CDS             complement(57084..57722)
                     /locus_tag="KB913_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6819155.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
BASE COUNT        19214 a        10112 c        11953 g        16512 t
ORIGIN      
        1 aaaaataagt aagtttaaca tttatattat tgacaacgct ttcaacgagg tgtattattc
       61 atgtataaat taaaggaggt cagttatgga agccacaatg ttgattagta gtgtcaagcg
      121 tgtaggcaaa gttgatccgc ggttgtacag ttcatttatt gaacatatgg gacgagcagt
      181 atatgaaggg atttatcagc cagatcatcc atcagctaat aaaagtggat ttcgccaaga
      241 cgtcattcac ttggtaaaag aattgaacat tcccatgatt agatatcctg gtggaaattt
      301 tgtgtcagga tttcgttggg aagacagtat tgggcccata gcaaatagac ctagaaggtt
      361 ggatttagct tggcggacaa ttgaaacgaa tgaagttggg attcatgaat tttataactg
      421 gtgtcagcat gtgggggccg aaatcaatat ggctgtcaat ctgggtactc gtggagtaga
      481 tgcagctcgt aatttagtcg aatattgtaa ttttcctaaa ggaacttatt ggagtgattt
      541 aaggcgttcg aatggtcaag agagcccttt tggaattaag acatggtgtt tagggaatga
      601 aatggacggt ccttggcaga ttggacataa aacagcggaa gaatatggac ggttagcaga
      661 ggaaacggct aaggcgatga aactcgtaga tgattcaatt gaggtggttt tatgcggaag
      721 ttcgaatcgg caaatgccta catttggtga ttgggagtta acagttcttg atcaagcgta
      781 cgatcaaata gattatttgt ctctgcatca atattatggc aaccaaaaaa atgatctttc
      841 tcattatctt gcacgttcct tagacatgga tcggttcatt tctgaagtga cagcgatgtg
      901 cgatacagtc aaggcgaaga aacatagtaa gaagcagatc aacctgtcct ttgatgaatg
      961 gaatatttgg tatcattcag cggaacaaga tgagcaagca gcgccttggc agattgctcc
     1021 tcctttacta gaagataact ataattttga agatgcatta ctattaggct gtctattaat
     1081 cactttattg aaacatgcag atagagtaaa gattgcttgt cttgctcaat tggtaaatgt
     1141 tattgcacca atcaggacag aaacaaacgg agaagcttgg agacagacga tctattatcc
     1201 atttatgcaa gctgctgtgt atggacaagg agaggtgtta agcccacaaa ttcgttcagc
     1261 aaactatgcg acggaagatt ttgaagaagt gccgtattta gaaagtatag ccgtaataaa
     1321 tgacaaagaa cttgtcatat ttgcagttaa ccgtggagaa gaagaaatga atctaactgt
     1381 tcacttgtct gaattatcat tagagggagt gattgatttt tctgaaatga gtggatttga
     1441 tacaaaagca actaatcttc ctaaaagtga acaagtaaaa ccaagtcatt caacaaatgt
     1501 aaaagctgaa gatgggaaaa tcaattgttt attgaaaccg ctatcttgga atgtggtcag
     1561 atgtcgttta tcagatgaag gaggaacaaa aaatgaaagg taaaaaatgg ttaattggct
     1621 ctttgttggt agctgcaaca ggtattttag gagcttgcgg tggcggaagt tcagcagaat
     1681 ctgattctga taaagaagtg actttgactt tttggaatgg gtttactgca tctgatggtg
     1741 aaatattgca agaaatcgtt aatgaattta ataaaacaaa tgataaaaac atcaaaattg
     1801 aaatggatat catgacttgg gccaatttga atgaaaaact tcctacagcg atttcttcta
     1861 aaaaagcacc tgactttatt gcattaaatt atccagattt tgcacagtat gtagaaaacg
     1921 gagcggtaca accattagac gatttctggg aatatgatgg agtagataaa tctgatttta
     1981 aagaaacggc tattgaatta ggtgaagtag aaggtaaaca gtattttgtc cccatgcagg
     2041 tacaaggcat gtatatgtat tggaataatg atttgtttaa acaagctgga ttagatactg
     2101 aacaaccacc tactacttgg gaagaattga cagaaatggc accaaaatta actgatagta
     2161 gtaaaaatgt atcaggtttt gtcttcaata aggatggaac tgcaccgtta tataactgga
     2221 tgttagcaaa tggcggtaaa ttagtgaacg atgattatac taagtctgaa tttgcgtctc
     2281 ctgagaacct taaaacgtta aaagcgatcc aaaaaatgat ccatgtagac aagactggtc
     2341 cagaatcgat ttctggcgcc gaaatggaca atttaatgaa tgctggtcaa ctagccattg
     2401 aaatcaatgg gccatggtta aataacggat tgaaagcaaa cgagattgat tataatgtga
     2461 ctaccttacc acaagggagt gattcagaca aaaaaacagc tattttagat ggcgtaggat
     2521 atgccattcc ggcaagtaca gataataata aaaaagaagc tgtctatgag tttttgaaat
     2581 attggaatac aactgaaatt ggtaaaaaat ggagtatcga aaatggtttt cctgcctact
     2641 tggattcagt agcaaaagat gaagaagtaa aaaatgatcc tattgtatct gaattatcga
     2701 aacaaatgga ctatgcagag ccatatttac caggttttac ccaaatctct gcgatcaata
     2761 acgatatcat caatccactg attgaaaaat tattagcagg agaagatcct gagacactca
     2821 tgaacgatgc agatgatgcc atcaatcaat tactgcaaaa atagtacaga actttataca
     2881 ggatagactg ttggcaagat acagatatct gaatgatcga cctagtattt gcagataggt
     2941 gttattgcaa aaatcacagc gattgttcgg atatcttatt cagattcgtt taaaccaaga
     3001 ttgtatattt tatcaaaatg aaagatgagg tggactatat gaacggattc accaaatatt
     3061 ggaatcgtcc tgatcgtgct gcgtatttgt ttttaactcc atctttttta gttttattat
     3121 tatttactgt cataccgctt ttaggaacat ttgctattag ttttacagat ttgaatattt
     3181 tctttacatc aagaaatttt gtaagttttg aaaatttcac acgtatattt agtgatgaac
     3241 gagcagttaa ttcgttgatt cattctttat atttcaccgt actcgaaacg ccaacacaaa
     3301 ttatcgttgg tttattagca gcagtagcat tatctaaaaa taccagattc aatcgttttt
     3361 gtcgttcgac attttacatt ccagttattt gttcattgac gtcaattgcg attatttttt
     3421 ctatgttgct tgatccgaat gtaggggcga ttccttactt gttttcacaa gtcggcttgc
     3481 cgatccctca attttttcgc gatccaaccc ttgctatgcc gacggtagcc atcatgactg
     3541 tttggaagaa ttttggtgtt actatgacga ttctcttgac tgctattcag ggaatctctc
     3601 cctctttgta tgaatctgct caaatggatg gtgcaacaaa tcgacagcag ttttttaaca
     3661 ttacgctacc tcagatcgtt ccctccttag gtttttgtat tttaacgaat ctgattggtt
     3721 cgatgcaagt gtttgaccaa gtatatgttg caaccgctgg tggcccacaa tttaagacag
     3781 aaacagctgt tcaatatatt tacagtcgag gatttacagc accttatgaa ttgggctatg
     3841 catcagcact gtcttcggtt ttgtttatca ttgttgcaac tatagctatc tccactaatg
     3901 tgtacatgtc acggaaagaa aaacaaatga aataggaggg aaacctgtat ggcaccagaa
     3961 agctcgatta cagttactgt gaatagtcga aaagcagtta gtggtaaaaa aatcattcga
     4021 acgattagta tgctagttat attgttggtt attgcgtttc cttttttgtg gctgattatt
     4081 tcttctttta aacacgaaaa agacattatc tcatttccgc ctagaatatt tgcagatagc
     4141 tataccctag ataactatat taaggtttgg acaacgatcc ctttattaga ttacatcaaa
     4201 aatacagtga tttttgctgg agggacagtg atcacttctg tattctttga ttctcttgcg
     4261 gggtatgcat ttgctcgtat gcgtttcaaa ggaaaatcag ttttgttcta tttcgttttg
     4321 ctgacaatga tgatcccatt ccaagtcttc atgattcctc tatttattga agtcaatttg
     4381 cttggcatgc ttgatactta tgcaggtttg atcattcctc gtatgacaac tgcatttggt
     4441 atcttcatga tgcgttcctt ttttattact ttaccagatt ctttggaaga ggcagcacgc
     4501 attgatggat taagtgagtt taatattttt ttgaaaatca tgttgccatt gagcaaacct
     4561 actcttttat cattagggat tttcacgctg atgaatagtt ggaatgactt gctttatcca
     4621 ttgatattga caagtagttc aaaaatgaga actttaccag cagggttagc tttatttaca
     4681 gggcagaaca tttcttttta tggacctgta atggctggaa cggttatttc aatgctgcca
     4741 ttactagtgg tttatatttt tgcacagaaa tattttgttc aaggaacagc tatgtctgga
     4801 atgaaagagt gaggaagatg aaaatagttg agactaaact ttatggacag ttgattgtgg
     4861 tttctgatta catcttatta ggtattctct gggtaatcgt gtgtttgcct gttattacta
     4921 tcgtgcctgc tacatgtgct gttttttatg taatggcgca atggaaaggt gagggatcag
     4981 gaaatatcat ttattttttc tttcaaggaa taaagcaaca ttttggtaag aacttgttcc
     5041 ttagtctgtt aacgatcatt atttattttc ttgttaatca attattagaa gaacagacaa
     5101 tcgtactttc aattagtgga tatgtagttt tacttattta ttccatgttt cttttatcct
     5161 ggatatatgt gatttctgaa aacaaagata tcacattttt acaaattttt gaacaaagtg
     5221 catggaaagt attttttgat tttttgagaa atattctttg ttgcgtattg ttattaggat
     5281 ttgtactgct catatttctt ttccctcctt ttatttttat ctttgctggt ggcgtatgga
     5341 aacttgtatc tattatcttg actataggaa atgaaaggta gggaaagctg ttggacgaag
     5401 aagtgaaagt aaaaatcaga gaggatttta cggtaggaga gatcagttct cggctgtttg
     5461 gctcatttgt tgagcatatg ggaagtgtcg tctatacagg gatttatgaa ccgggccatg
     5521 aaacagctga tggtgacggg tttagacaag atgtcctctc ttatgtaaag gaattagaat
     5581 taggtgtcat tcgctatcct ggaggaaact ttacatctgg ttatgattgg gtggatactg
     5641 taggtaggaa agaacaacga ccaaaaaaaa ttgatttagc atggcgaggt atagaaccaa
     5701 attcttttgg actccacgaa ttttttaaat ggatcagtca tgtacaagcg aaaccgatat
     5761 tcacggtgaa tttaggaaca aaaggaattg atgaagcaaa aaatttagta gaatattgta
     5821 attttccaaa aggaaccttc tggagtgatt taagaataaa aaatgggcaa aaaaagcctt
     5881 ttggcgttaa attatggtgt ttagggaatg agctagacgg tccatggcaa gtgggggcta
     5941 agagtgctta tgaatatggt aggttagcaa atgaagcctc aaaagtcatg aagttagtgg
     6001 atgattcaat tgaaacaatc ttagttggaa gctctacgcc acgtttacca tcgtaccctg
     6061 aatgggatcg tatcgcatta gaagaagctt atgagaatgt agattattta gctttgcata
     6121 actatattga taagtatgat gaagaagact tgactaaacc tcctaaaaat gagcgtgatg
     6181 atacagcgac ataccttgca aaagcttatc gattcgatcg tcaaattgaa gaaatcgttg
     6241 ctacttgtga ttatgtaaaa ggatatttga gaagtgagaa aacaatgtat ctagcgtttg
     6301 atgaatggaa tgtacatgcc caaccggaaa aaagacatag ggattttgaa gtcggtagtc
     6361 ccatcgattg gtgttacttt actatggaag atacattatt atttggttca ttagggctgg
     6421 ctattttacg acacgcagat cgcgtaaaga ttagttgtca atcattgtta gtaaacacaa
     6481 tacctttaat actgacagat gctaaaggac aagcatggag gaatccaact tattatgtga
     6541 tgcaacactt atcgaaatat gctaaaggtc aagtattgaa acaacaaatc atttgccctg
     6601 tttatgattg tgaaaagata aaaaatgttc cttatgtgga cagtgtgatc gtagataacg
     6661 gcaatcagct gactattttc ttgatcaatc gcacaaatga acaacaaaag ataacgattg
     6721 aacatgattt caatttgcta gatcaaggag agcactacac attaaccagt agcgatctgt
     6781 tggacaaaaa tacacgtgaa gaaccagaaa aaataaaacc tgaaataaac tatttttcaa
     6841 tagaaaaaca tgacgaatta aatgtaggga tagaaaaata ctcttggaat gtaattagaa
     6901 taaagaaaat gtgaggaaat ttgttatgat gaagacactt tataataatc ctatcgttcg
     6961 gcaacgggca gatccttggg tatataaaca tacagatggt tattattatt ttacaggatc
     7021 ggttccaggc taccaagtga ttgaattaag aagggcaaag tcactgaatg aattagaaca
     7081 tgctgcaagc ctgattgtat ggcaggctca tgaagaagga ccgatgagtg aattgatctg
     7141 ggcacctgaa gtccattata tcaatggaaa atggtatatt tactttgctg caagcaatca
     7201 taaaactata cgtgatgaat ctcatcatca ccgcatgttc gtacttgaaa atcagcatat
     7261 agatccaatg aatacagatt ggatagaaaa gggacaaata aaaacgaaaa gggaaacttt
     7321 cagtttagac ggaacaactt tctcttctca aggaaagcta tattatgtgt gggcccaaca
     7381 agatcctgaa attactggga attctaatct ttatctatcc gaaatggata atccttggac
     7441 gttaaagggg aagcagatcc tcctttctat acctgagtat gaatgggaaa aacggggttt
     7501 ttcagtaaat gaaggtccag cagtccttac tcgcaatggg aaaatattca ttacgtattc
     7561 tggtagtgca acagatgaaa actatgccat gggcctgctg tgggctgatg agcacaagaa
     7621 tcttttatta aaagaatcat ggcataaatt atcggagcca gtattcgttt cttctaaaaa
     7681 aaataagcaa tttggtcctg gtcacaactc gtttacggtt tcagaagacg ggtgctttga
     7741 tattttgatc tatcatgctc gaccagagaa gaaccaaaaa ggggatccgt tagacaatcc
     7801 taatcggcac gcgaacgcgc aatgctttac gtggaatgag caaggatttc cagaatttgg
     7861 tgaacctgtt ccgtatgcct tatgagcaca agaaaccttg atttttgctt gaataaacct
     7921 tgcagactcg ttatgatata tgtacgtaca aataaaaagg ggcaaggcaa atggcaaaat
     7981 atcaagatat tgcagaagag ataaaacaaa agatccttcg tgaggaatac gaagtaaata
     8041 caaccattcc ctcagaattc aagctgcaag aaatatatga cgtcagcaga catacgattc
     8101 ggcaagcaat cgctgtgttg gtaaatgagg gctatctgcg taaagaaaaa gggtcgggca
     8161 catatgtaga tgacagctat aagaaagaaa aaacaccatt gaacagaaca aaaacgatcg
     8221 gtgtcatcac cacatatctc tctgattata tttttccgtc gattatccga ggaatcgaaa
     8281 atgaattacg agaatctggg tattcattgc ttttagccag tacgaataac gatcacgaat
     8341 tggagaaaga gtgtttgaag aaaatgattg cttatggggt agatggtttg atcgttgagc
     8401 ctacgaaaag taatcagtat aacccaaact tagcacttta tgttgctttg agagaacaag
     8461 gcattccgat ggtgatgatc aatgctgctt atgaagagtt aaatgcctct tatatttgtt
     8521 tagatgatgt gaaagtcggt tttatggcag cagaatattt gataaaaaaa ggacatcagc
     8581 gtctgttgtt catcacaaaa atcgacgatc ttcaaggaaa atacaggatg aaaggtttta
     8641 tcagcgcgtg tgaacagtat aatgtgcgtt ttttgacgga agatatcatt actttcacca
     8701 cggaaacacg agaaacaatc gctgaaaaaa cagtacaacg gttgaaagaa gaacaagctt
     8761 tagatggcat catttgctat aacgatcaaa tagctagttt aatgctagat aagttgacag
     8821 aaaatggcta tcatattcca gatgacctat cgatcgtagg aacagacgat tcttctttaa
     8881 gccatttagg gaataaaaaa ttgacaacat tgacgcatcc aaaagaaaag ttgggacaag
     8941 atgccgcacg gtggatcgtc acaacgattg aaaaaggaca ggcacagcca aatattctct
     9001 atgaacctgt actagttgaa cgggaaacag tgaaagaaaa cgaaaaataa gagacgggtt
     9061 tttaccgcct cttattgctc ctacggttac tcgtcgcaat gtttgtgaga gcttttgtca
     9121 tcgctcaagg ctgaacgttt ctttcaccac ctctccacta aacggtgttc tcctaccaac
     9181 tggtcacaag tcacaatatt catcaaacat gagaagctgt tttttgaaat tgttccttgt
     9241 gactggaaac taagcggttc cttcttattt cttgaagctg accacttctg tcacaacctc
     9301 tttaagaatg atggatagaa atacgtttag gataagtttt tttagatgca ctttgttcga
     9361 tttcctctaa agatttccca cgagtttctg gtacgatctc ttgaataaat aaaaccccta
     9421 aaaagcagat gatcccaaaa atgccgaaaa cgatttcttg agacatagaa gcagtcatca
     9481 caggaaaaag caagccaact aggaaagaac caatccaatt aaaagaagag gctaggccag
     9541 atgctcgccc gcggacagct agtgggaata tttcgcctac gattacccat gtcagtggag
     9601 cccatgtgca agaataaaat gcgacataaa tacataaaaa caagagaatc aacaacgaat
     9661 ttgtatgagc atccagtaca gttcctaaaa cagctggtag gatgaaagaa agtcccatca
     9721 cgctaccgcc tattttcaat aaagttcgcc gattgaactt gtctgcaata accaaaaaga
     9781 gcaaagaacc agcaactaaa atgattcctt ggatgatcgg ccacatcaat gcatcgctcg
     9841 ctgcatgccc agtcgctttt tctacgatca gcggaatata gtaaaaaata gcattagctc
     9901 cttgaaattg ctggaatact gctacaccaa taccggcaat gactaaggaa cgatattttt
     9961 ctaaaaacaa agtatgccaa gaagttccgg ttgtcttttc ttgtttgaca ttcagctgga
    10021 tttgttcgaa ttcctgttca gcttcttttg gtgtccgaat atagttcaat actctttttg
    10081 cctcttccaa gcggccagat tgcataagaa aacgcggtga ctctggtaga gctaaaacac
    10141 cgaaaaataa aatcagcgcg gggacagcag cgagccctaa catcacgcgc caagccatcg
    10201 tttcaggcaa cccttttagc aaataatctg caacatagga aaggagcatg ccagaagcaa
    10261 tcatcacttg attgatccct gacaatcttc cccttagtct agcaggagcc atttcagaca
    10321 tataagcagg aactagggca gatgcagcgc caacagctaa acctagaaga atccttgctg
    10381 caatcagaaa ataagaacca ttgtgagggg cagatgcaga aaggacagaa ccagccataa
    10441 aaataagtgc agaaagaaga atcatttttc gtcgtccaag cttatcagaa agaagaccag
    10501 ataaagagcc gccaaggatc gcacctaaca tgaccgaaga cgtgatccat cctatcaaag
    10561 aagctttacc tgccaaaccc caatcatgct gtaaaaaagg taaggcgccg gtcataacac
    10621 caatatcata tccaaataga atgccgccaa atgcgccaaa aaaataaata aacgatgagg
    10681 aaactttttt ttcttttttc ataagtattc tctccttcta gaatttcgag aaggcggttg
    10741 atcagatttt gtaagcaatt tcattttata acttatgtac gtacaaaaca agtgtttttt
    10801 attgtattct tgtaaataac tgcttgacat gtacgtacaa aagtatacaa taatcattgt
    10861 aagcgctact aaaaagacgg tttgatcagg tttgacgaga aggagggagt taaatcatta
    10921 tgaaggaagt aaatgcgcaa agtatgttag atgtcataga tggtcgtaca tctttaggga
    10981 ttgagtttgg atcaactagg atcaaagctg tattgattga ttcatctttt actcctattg
    11041 ccgctggtag ttatgagtgg gaaaacaaac tagaaaatgg tatctggacc tattcattag
    11101 aagatatttg gaaaggactg cgcgtcagtt accgaaaaat ggcagcagaa gtattcgaaa
    11161 tctatggcga gaatcttacg acaatcgggt cgattgggtt cagtgcaatg atgcacggtt
    11221 atctagcatt tgatagcaag gaacagttac tagtaccatt tcgtacttgg cgaaatacaa
    11281 tcactgaaga agcagaacga atattaacgg aaaaatttca atacaatatt ccgcagagat
    11341 ggagtatcgc tcatttgtat caatctattt tgaataaaga agaacatgtg aaagaaatta
    11401 attttttgac aacgcttgca ggttatgtcc attggcagct tactggtgag aaagtactag
    11461 gcgtaggaga tgcatcaggc atgtttccta tcgatccttc aacgaaaacc taccatcaag
    11521 aaatgaaaaa tatttttggt cagttaatcg aaaaagcgca cgtagcgatt gacttggatc
    11581 acattttgcc taaagttcta gtagcaggag aagaagctgg caagttaagc gaatcagggg
    11641 cttatctgat cgaccctacg ggaaatttga gaccaggaat cccggtttgt ccgccagaag
    11701 gggatgcagg aaccggtatg gtcgctacga acagtgtagc caaagggaca gggaacattt
    11761 cggctggtac ttccgccttc gctatgatcg tattagaaaa agaactagaa aatgtccatc
    11821 cggaaatcga catggtcact acaccttcag gagaactagt aggcatggtt catacgaata
    11881 actgctcttc ggatatcaat gcttgggtca gtatttttga agaatttacc aattctttgg
    11941 gtatggagat aagcagagat aaattattca cggtattatt caacaaagcg ctagaaggcg
    12001 atacggattg cgggggatta ctttcttatg gttatttttc cggtgaaaac attacaggag
    12061 taaatgaagg aaggccatta tttgtacgta caccaggtag ccgttttgat ttagcgaatt
    12121 tcatgcggat ccatttagcc agtgcttttg gtgcaatgag aatcggaatg gatatattga
    12181 aatctgagaa tgtccaaatt gatcgtttag tggggcatgg ggggattttt aaaacaccag
    12241 aagttggaca gcggattcta gcatctgcta tggaggcacc agttacagtg atggacacag
    12301 ccggagaagg tggagcgtgg ggaatcgcgt tattagcagc ctatatgatg gatcgacatg
    12361 ggaagtcttt agaaaacttc ttggcagaag acgtgtttgg acaagaccaa ggaatcacca
    12421 tcacaccttc agcagaagaa atagcaggct atcagatatt tatgagacgt taccgtgagg
    12481 ggatcgacat tgaaaaaaca gcgattcatc aattgcaaga aaaaggagtg atagaaaatg
    12541 ctggaacaac tgaaagaaga agtataccaa gcaaatcttg acttgcctaa acacggactc
    12601 gtcaaatata catggggaaa tgtgagcgct tttgatcctg aaacacgata tttcgttatc
    12661 aaacctagcg gagtcagtta tgaagagatg acagcagacg acatggtcgt tgtggacttg
    12721 gacaatcata tcattgaagg taaactcaat ccctcttcgg atacgcctac tcatgctgtt
    12781 ttatatcgtt catttcctca aatcggagga atcgtccata ctcactcgac atgggcgacg
    12841 atctgggcac aagcaggatt ggatgttcct gcgatgggga cgacgcatgc agatactttt
    12901 tatggatcgg taccttgtgc tcgatttttg acacaacagg aaatcgacag cgggtacgaa
    12961 tatgaaacag gaaaagttat catagaaaca ttcaaagaac gcaaaattga tcccttagca
    13021 attccagggg tacttttaca cggacacggt ccatttactt gggggaaaga tgcgcaaagt
    13081 gcggtaatga acgcagtcgt actagatgaa gtatgcaaga tgaatttatt taccagacag
    13141 ctcaattcat tttcagaaga gctgcctcaa cggattttag ataaacatta tttacgaaaa
    13201 cacggaaaaa atgcgtatta cggacaaaac aaataaaagg agtggctaat tatgttgaat
    13261 attggagaaa aagaattttg gtttgttgta ggatcacagc atttatatgg ggaagaagca
    13321 ctgcgagaag taaagaaaca tgcacaagaa atggtcgatg aactgaatga aaatggccaa
    13381 ttgccttatc caatccgcct tcaagaatta gcagttactg ctgatacgat cacaaaaatc
    13441 atgaaagagg tcaattatcg agaagaagta gcaggtgtga tcacttggat gcatactttc
    13501 tcaccagcaa aaatgtggat ccgcgggaca aagcttctac aaaaaccatt gcttcattta
    13561 gctacgcaat ataacgaaag cattccttgg aaaacgatcg atatggattt catgaattta
    13621 aatcaatccg ctcatggtga ccgcgaatat gggttcatca atgctcgatt aaataaacaa
    13681 aataaaatcg tcgttggcta ctggaaacga cctgagatcc aaaaagagat tgctgattgg
    13741 atggatgttg cagtagccta taatgaaagt tttggaataa aagtggctcg ttttggtgac
    13801 aacatgagaa acgtgggtgt cacagaagga gacaaagtgg aagcacagat tcaatttggt
    13861 tggactgttg attattttgg tatcggagat cttgtacaag taatcgatcg cgtatcagac
    13921 gaagaagtcg atcaattatt tgaagagtac aaggaattgt ataccttcga ctatggtgat
    13981 tatgaagaaa agacatggga ggaacatgta aaagtacaag ctcagcagga aatcggtatt
    14041 cgccgtttct tagaagaagg aggctataac gcttttacga ctaattttga agacctgtat
    14101 ggaatgaaac aactacctgg actagctgta caacgtttga tggcagaagg atacggtttt
    14161 gctggggaag gcgactggaa aactgcagcg attgatcggt tgctgaaaat catggctcga
    14221 gggaaagata caggattcat ggaagattat acttacgagc tagctagtgg ccaagaagca
    14281 atcttggaat cccatatgat ggaagtagat ccgacgcttg ctgcgacgaa accaagaatc
    14341 gttgtttctc ctttatcaat gggagataga gaagatccgg cgcgtcttgt atttgatggg
    14401 aaagcaggag aaggggtagt cgtatcgatg gcagatttcg gtacgcatta taaactgctg
    14461 atcaatgaag tagaagcctt tgaaccaacg actgaagcac ctaatttacc tgttgcacgt
    14521 gtgttatgga aaactaaacc gaatttccat gaaggtgtcc attcatggat tcaggcaggt
    14581 ggcggtcatc ataccgttgt ctcgctaaat ctaacaacag atcaaattga aacgtgggca
    14641 aaattagttg agttggaaac agtggttatt agataaaaag aggttgtgaa aaagccactt
    14701 agttttaaga aataagaaga gattgacgaa atttgctttt caactttttt gaaatttagt
    14761 cttattatca atgtcagcta acggaacacc atttatcaag atatctcacc ctcaatattt
    14821 tgctctcgaa aataaggctt atggcagtaa cttgtcatag ccttattttt atcactcagc
    14881 ctactctgct ctaactgctc tttttgcttc taggaagtca aatggtaaac agttgtctaa
    14941 ttgcagaaat ttcgagatac ttgttagtaa ggagggggtt ttatgtatca cgttcatttg
    15001 attgatgcta ttccagaaca agagatagaa aagttacaag gggaatattt caaaataata
    15061 gatgatttgc cagccgaagg aatagttatt cgtagtacga aagtgaaaga tgaatggctt
    15121 acaccagatt tgctagcaat ttcaagagct ggtgttgggg tgaacacgat caacgttgaa
    15181 aaagcttctg aaaacgggac gatcgtcatg aatacaccag gtgtaaatgc taatgcagta
    15241 aaagagcttg ttttgtgctg tttgctctta tcttcccgtc cgataatcga agcaagtcgt
    15301 atggtacaaa cactaacagg tcctaatatt ttagaacagg cagaaaacaa aagaagtgct
    15361 tatgtgggac gagaattgca aggcaaaacc atcggtcttc ttggtcttgg agcgataggc
    15421 acaaaagtag cgctaagttg ctatagctta gggatggatg tcttgggtta ttctatccgc
    15481 gatgcccagt tggattatgt tcggcaagca gatttagaaa cagttctttc tacctcggat
    15541 tacatcgtag tcatgctgcc gttgacagaa gatacaaaag gattgatcga tcaggcgaat
    15601 atagaaaaaa tgaaaaaaga tgctgtactt atcaatgtag gaagaagtga aattgttgat
    15661 aaatatgctg ttatgcaagc attggaaaaa caacatctgg ctaaatactt gactgatttt
    15721 ccagaagaag agttcttaga aaatgaccgt atacttatgt tgcctcatct agggggatcg
    15781 actcaggaag ctttggcaga cagcggacgt ttggcagttg aagccttaaa agattatctt
    15841 ttgttcggta cggttagaga agcggtcaat tatccatccg cacgaatgtt tttccaagcg
    15901 ccgtttcgat tcactatatt ttatcaaaag aaaaccaata tattagcaga gatattttct
    15961 ctgctgaatg agaacgagct agcgatcgca gatatatcgc gtaaccataa gaatgagcat
    16021 gtctacatat tgattgacat agacagtact gattttgaac agctcaatca agtgaaacaa
    16081 cagctagaaa aaatttctgg agtacgaaag gtccgcttat taaagaaacc agaaaggcca
    16141 taaagaaaga gaatatttgg atttcattaa ttcttctttc cgttctttac tttcgaattt
    16201 cgtacaacta aaataagaga agcaacattc ttttattgat agaaatgaag gagcaagcat
    16261 ttgaaaagat atataagcag actttcgacc aaacagaaaa agattttaaa aggaacagca
    16321 gcaatcatca gtatcttttt tcttgttgtt tttagtaatt tatttttgca gtggtgtcaa
    16381 aatgatctat ccgtagacct tgcgttgaaa tttgcttttt cttggcatac ggaaaaattc
    16441 ttcttagcct gtctcgtctt gctgattatt cttatttttc tgattgcact agcaggatct
    16501 gtccctttag gttcccttac gtatgtcgta gccatcggtg tattaggttt tgcaaattat
    16561 atgaaaatga gttatcggca agaaccgatt tatccagacg atttgaagat gatcactgaa
    16621 atcggattgc tgaaagatat gaccggcact atgctgttta cagtgatctt agctgccgca
    16681 ggaaccgtga taggattgtt ttgctggtac atgtttcgaa gcctgaaaaa aggaaggcga
    16741 ttccaattga tccgattaac gacactgctt gtggcaattg gactgctagg gtatatcagt
    16801 aatttcaaca atcccgataa tttgttgcga aaagcatata ataaaacggc actatggata
    16861 ccttacagcc agaaaatgaa ctactataac actggtttta tcggtgggtt tttgtacaat
    16921 ctgaaggtag aaccaatgga tgaacctgaa ggatattcga aagaaaagat caaagaaatc
    16981 actgaaaaat accagaagct agccgatgaa aaaaataaaa ctgtagagga agagtcgccg
    17041 aacatcgtgt tcgtgatgag tgaaagtttc tcagatccta gtcgattaaa cggcgtagaa
    17101 gtatctggtg agccattggc agattattat gaagtagctg atcaaacata tagtggcaat
    17161 atgctttctc aaaactatgg cggtggaaca gcaaatatcg aatttgaagc attgactggt
    17221 ttttctatgg cgttatttaa tgcgcaactc accacccctt acacgatgct tgtaccaaaa
    17281 atggatcagc ttccttctat cgtttcagcg ttaaacgcac aatcatacca gacgacagcg
    17341 atccatccat acaatacttc gatgtataaa agagaggatg tttatcagac attaggattt
    17401 gaccagttca tcagcgagcg tacgatgacc tatacggata cgatagagaa taatccatat
    17461 atttctgatg agtcagctta caaagaagta atgacacttc tcaaggaaga aaaaacacct
    17521 cagttcattc atttagtcac gatgcagaca catatgccct acgatggaaa gtatgataat
    17581 ctagactatc ctgcaaaaac ttcagatgga agtgggacac ttgacttaga gaattatctg
    17641 caagatattt cctatagcag cacggcactg aagcagttca cggaagaatt gaagaatctt
    17701 tctagaagga ctttagttgt tttttggggg gatcatcttc cagggatcta ttcagatacg
    17761 atccaagcaa aaaatgacaa acaaacattg catgaaacac aatttcttat gttcgacagt
    17821 aaaggagaat tagaaaagca aacgactcac gatgcaatca ccagtccgtt ttattttgca
    17881 gcgaatctaa tggaacagac gaatcagaca acaaatggct tttatcagct gcttttatca
    17941 ttagaacagg aacttccggc gtttgaacga gaactgtact atcaaaacgg acagtggtat
    18001 aaagaagcgc aattcaatcg ctcgcaacaa gagatttacg acgaatatca attgatccaa
    18061 tatgacattg tcgcagggaa acaatatagt ttagcagatg gtttctttga gcacgaataa
    18121 gaatggcgag ctgtatagaa accattaaat tttttcaagt acttgtcatt tgaggataaa
    18181 aacaagtaga ataaataata acaacaatgg agaaagtagg aaaacgaaca tgttaccgaa
    18241 tattggctat tatgtgcagt ccatcgatca aatcgtcaag gaaacagaag caatcggaga
    18301 aggaatgcat ccgaaatatg aagtgatcag aaacgcaatt gatgaaggaa aaacaagtga
    18361 actggacaaa tcgactcttg aagagatcat cctgttattt gaagaaggaa caaaaaaata
    18421 tcgggcaatg cttatgaaag tcagtacttt gcgtccacca gcaaaagcaa tgggcattca
    18481 taaaaatttt gaaaaagctt atctttcata tgtagcaggc tgtgaagaaa tgatccaaag
    18541 tatcgatctt gaatcagggg tagatgaaga tctattcaat acatctgaag caaaacaaga
    18601 ccaagcgaca gaccaattga cagctgccat ccaaaaaatg actaatttgt tgttgaaaaa
    18661 ataaaagaaa tctttgataa caataaaaac tagagttatc taatataaat gtaatattac
    18721 ctttatgata gagtgatcaa aatcctttat gataatgaca tacctataac caacaacaac
    18781 cttgtactta ctcaaaatcg agtaaatact ccttttccgt cgagtctaac catctcggcg
    18841 gttttttatt tgtagaaaag aacatcagga tagacggaaa agtcttgtcc tgatgttctt
    18901 ttcagatagt atggaaagct gattagtttt ctacattctg tacatattgt tcaaagtagt
    18961 tctgtaaatc ggctttgagt ttctgatatt cctcttcgct atactcttta tcttcgattt
    19021 tcccatcaaa gaaaggaata tttagttctt cccgtagtct gtctaatacg tcttgctgat
    19081 tcatttcatt ctccttttct tactaacgat caaaataaac acagacacat tctggtacat
    19141 agacatcttt tttcagtaat tccagtaatc ctgtttcagg atgacggcga tataatgtca
    19201 gattatcggt gttctgattg gcacacacga caaaattatt gcttggatct agtgcgaaat
    19261 cgcggggaaa atccccttct gttgagatga tttgcttgtt ttgaatgtgg gaaccatctt
    19321 caaaaactgc gaatacagca atcgagttat gtcctcggtt agaagcataa aggaacttgc
    19381 catcatttga aatgcggata gctgcccctc cattttcacc gtcgaattct tctggcaagg
    19441 tcgatatttt ctgtaattct tcaaaagcac ctgtttcttt attataagaa agcacgcgga
    19501 ctgtgctgtc taattcacca aataaataag cgaattgtcc atttggatga aagacaagat
    19561 ggcgagggcc tgttcctggc tctgcagtga aggtagttac aagattcaat ttgccgtttt
    19621 cggacacatc ataagtatac acacgatctg taccaagatc acatacgact aatcgttggt
    19681 caggagtcag atccgtatag tggacatgcg catgatcttg gtttttatga ggacctgtcg
    19741 cttcttgatg gaatattgaa tctgctgctt tcagttcgcc atctcctaat atatggtaga
    19801 catttacttc acctttatga tagttcgccc cgtatagtaa ttgacgtgct tcatcaaccg
    19861 ctacataaca caaaggagcg ccagactctg ttaccgcatt caaaaaatga aaatccttat
    19921 cgtacgcacc ggcaccacct aatccatcca cactagtaac tgtgtaaaga ttgccagctt
    19981 tactttttgc tacataggta gggctatttt cttcaacagc taatgaaagg ttggctaatt
    20041 cttctttttc tgtatcaagg tcgatcgtat agattccttt actttcgcga cgcgtatagg
    20101 ttcctaaaat tatcttttcg atcatatgag ctgattcctc ctaattgtaa tgaaatagtt
    20161 ttcgttttta ttctatcaca taattattcc acacggctaa agaatgagaa tgtgttatac
    20221 tgtttttgaa agcaattaaa ggagagagtg caatgattca ggcaaagatt acagaaattg
    20281 ggacagaagc aataaacaag gaagaaccca tgctgatttt gttcgataaa acagcaacag
    20341 ctgccttacg aaaatattcg gtgattcaag aagtatcaaa agacgaacct ttttctttga
    20401 aagcaggcgg aacaattgct tttgatgatc aggtatatac gatcgattat gtcggtccga
    20461 tggccaatgg gaatttaaag acagtagctc acgtatcatt gatttttgat gcttgtccag
    20521 aagaaggaca aattgcaaat ggaatctatc ttcatccgca tagactgcct gctattggtt
    20581 tgggaagcca aattttttat aactaacagg aggaattatg gaaggaaaaa ataagaagaa
    20641 cagaccggta tcgtggtttt ggcgctggtt tttaaataat caagtagtca cagccttact
    20701 tgttgtattg ttaatattgc tgatcgtctt tttatttaca aaagtttcat atttgtttgc
    20761 accaatctgg caatttttag caatcgtagg tctgcctatc attttagcag gaatcttgta
    20821 ttacttgatg aatccggtag ttgattactt tgaaaagcga aaagtaccaa ggctttacag
    20881 tatcattggg ctgtttgttt tggttgttgc actaatcgca tgggggagcg tagtgatcat
    20941 ccctaagatt caggaacaaa cagtgagctt catcagtaac ttccctcaat atgtagatac
    21001 gattgataat aaattaaccg agattttgcg ggacccgctg ttcaaccaat ttcgcgaaca
    21061 gttggaaaca gcaggtgata agttcatgaa ttcggcaggc gatatgatcc aagatatatc
    21121 taagagtaca gttcagagtc ttggaagttt tgtcggcgcg gtagcgacta ttttagtggc
    21181 tctgctgacg atgccgttta tcttatttta tctattgaaa gacggtaaac aattagcacc
    21241 ttattttgtc aaatttttac cgacacgcat gcaaaaaccg acgttgaatg tgctgagtga
    21301 aatgaatagt caagtttctt cttatataag aggacaacta actgtggctt ttgctgtggc
    21361 aatcatgttt atgattggtt ttgcggtcat tggtttagag tatgctgtca cgttggggat
    21421 tattgcgggt tttttaaacc tgatccctta cttaggatca tttttagcga tgattccggc
    21481 tatcttttta gccattgtag caggtccatt catgatcatc aaagtactga tcgtttttgc
    21541 agtagagcag acaatagaag gacgcttgat ctctccatta gtactaggga atcagttagc
    21601 aatccatcca gtaacgattt tattagttct gctgacttct gggaaattgt tcggaatcat
    21661 cggtgtgatc ttggggattc ctgtttatgc agcagctaaa gtagtgatta ctcatgtttt
    21721 tgaatggtac acaacaatct cttctcttta tgaagaaaat ccgttgaaaa agcagaaaga
    21781 ataacaaaaa gagacagatg ggaaaatatc caaggcacaa atgctgcttt gaagattttt
    21841 tcctctgtct cttttgtatg catttatctc aatttttaaa atgatttacc taaagcagca
    21901 gctttatcta atgcattttg catcaactca tctgcacggt cagggtcata atcgattcct
    21961 tcgatgaata gctgatctac ttgatcgatg cctacaaagt ttaaaatacc ttttacatat
    22021 tgagaggcaa agtcttgtcc gttgtataca ccgccattag attggatgtg cagtgctttt
    22081 ttacctgtca ctaatccttc tggcccgttt tctgtatagc ggaacgtttt tccagctaca
    22141 ttgacggtat cgaaccaagc ttttaatttt gttgggatat ttagattcca taaggcgttt
    22201 gcgataacga ttttatcagc agcaaggaac tgatcagtca attcattgaa acgagcaatt
    22261 ttttgttgtt gactttctga taaggaagtg aattctgcac cagcacgtaa tgcttcccaa
    22321 cctgataata attcttcatc gatttccgga atatcatcgc gataaagttc caaaacagtc
    22381 acttcatcat ctggatgatt ttctttataa cttgttaaaa aagacgtcaa tgccttaact
    22441 gtgcgcgatt cttctgcagt taggggatga cctttgacta ctaaaacaga tgccatatgc
    22501 ttaccttctc cttttattgc tatgattgtt ataactatga ctaacaaaat cagtttactc
    22561 gaaaaagaaa aggctatcaa gtcatattga taaggttgaa gaataaataa ctaaaaaaag
    22621 acagggtata aaagaggctg tgacacgatt ttttgtcaca gcctcttttg aatctaacaa
    22681 gcaatattca agcaacactc gactgaagag cttccatccc accaatgata taaacagcac
    22741 gaaaaccatt agcagtaagt tgatcggcta atgcttctga tcgcctgcct gtatagctta
    22801 gaatataata aagtttcttt ggatctagat tttttaattg tcttggcaag atagcagcgg
    22861 ggatagaaag cgagtggctt aagtggtttt ttgtgtaatc taaggtattt cttgtatcta
    22921 aaacgatgct gtcagcatcg agaggcaatt tattgaagtc ttggacacta attgattggg
    22981 ccatttatct catcctttgt ttagtatgtg gctattttaa tgggcaactc tcattaattc
    23041 aaatggaagg attcctctta tcactttttt aatgtatcgg atgataatga aaaaaactat
    23101 gcaaatgtct tgcaaaacag gtaggaggtg ttataatgac atagcgtcat atgacaatgt
    23161 gtcatcttga aagaaaggag aatccatatg ccgacacaga catttttcca tttgcctaaa
    23221 gaaaaacaaa aaagactaat cgaggctgcg agaatcgagt tttctagagt acccttaaaa
    23281 gaagcttcga ttgctaatat cgtcaaatta gcggatatcc ctagaggcag tttctatcag
    23341 tattttgaag ataaagagga tctttatttt tattactttg agacaatgag acgtgacagc
    23401 tctaaagata tgttacaact aatgaaagaa tccgatggtg atctattcaa aggattcgaa
    23461 tcctattttt ctaaaatgat ttatgagatt ttggaaggcg agaatgcttc tttttatcgt
    23521 aacttgttta tgaacatgga ttaccgtgcc tcaagaaaag tcgctcctca tacgagtcgc
    23581 caaaaaacgc ctcacgatcc acataaagaa cacaaacaag atgcaaaaga gttgcttgaa
    23641 ttgatcgatc ggacgaagct gaaagtaaaa aatgatcatg aattggaatt actgatccaa
    23701 ttagtgatga atactgtatt tacaacaatt gcgcattcgt atcgcttatt ttcaacatct
    23761 gaagattact cagtagagca agcaatcagt gaattcaatt tgaaactttc ttggctgaaa
    23821 aacggagtat ataaatagaa agaagggaac tagatgctaa aaatcgtaaa acggatctcc
    23881 ttgacttcag caattgcagc tgcagttttc atggtgatcc aagtactggc agatttatat
    23941 ttgccgacac ttacctccaa tattattgat aaaggggtag cgcaaggaga tgtcgattat
    24001 atttggcata caggttttgt gatgatcggc ttttctttga tcagtatctt agctgctatc
    24061 gcaaatacat tttttgctac tcgtgaatca cagaaactgg gtaagcaatt gcgtacggat
    24121 gtctataaaa aatcagagag tctgacaaaa gatgcgtttg ataaatatgg aacggcctct
    24181 ttgatcacaa gaacgaccaa tgatgtgact caaatccaaa tggttacaca aatgttttta
    24241 cgtatgatga tcaatgcacc aatcacgttg attggcgcga gcatacttgc ttatcaaaaa
    24301 gatcatcagt tgacaaaaat cttcttagtt gtcatcccag taatgattat tttgatcggc
    24361 ggaatcatgt actttgctgt tccattattc aaaagtatgc aaaagaaaac tgaccgttta
    24421 aacctggtat ttcgagaagg attgacaggg gtcagagtga ttcgagcatt cgataagaca
    24481 cgctttgaag aaaatcgttt tgatttagcg aataaagatt atacaaatac ggcaatcaaa
    24541 gttaatacga tcgtcgcatt gatgatgcca atgatgacat tgatcatgag cggtacaaac
    24601 gtagcaatca cttggtttgg tggacactac atagcagata tgactttgga agtcggtaat
    24661 ctgattgcat ttatgactta tgcgatgcag atcttgatca gctttatgat gctttccgct
    24721 atttttatca tggtgcctcg tgcacaagct tcagctgacc gtattaatga agtgttggat
    24781 gaaaaaatcg gtatccatga ccctgaaaat cctaaaacag tttcttttgc tggaaaaaac
    24841 gcaacattgg ccttcaatca tgtcaattat cgatatcatg gagcagaaaa acttgcattg
    24901 gaagatattg atttccaagc caagtcgggc gagatcgtcg caatcatagg ggggactggt
    24961 tcaggtaaaa cgaccttagt caatttgatc cctcgattat atgacatcga atctggttcg
    25021 atccaaataa atggaacgga cattagtgac atgactcaat ataatttgcg agaattaatg
    25081 ggctttgttc ctcaaaaagc agttctgttc tctggaacga tccgagacaa tatgcagtat
    25141 ggtaagccgg atgcaacaga tgaaatgatt tggaaagcat tagaaatcgc acaagctaaa
    25201 gattttgttt cagagatgga agatggctta gatagccatg tggaacaagg aggaggaaac
    25261 ttctctggtg gacaaagaca gcgtctggca attgcacggg cattagtcaa aacagcagat
    25321 atctatgtgt ttgatgattc cttctcagcg ttggatttca aaacggatgc caatcttcgc
    25381 caagcattga aaacgaatat gaaagaaagt atcaccgttt tagttgctca acgagtaagt
    25441 acagtaatgg atgcagatat gatccttgtg ctagatgaag gaaaactggt tggcaaagga
    25501 acacatgaag aactattagc aacaaacgaa acttatcaag aaatcgttca ttcacaacta
    25561 agagaggagg acttagcatg agtaaaacaa acacacgtcc ctctcatgga ccagcaggcg
    25621 gtccaggaca tggtggacct ggcagaaatc tcggtgtaaa aggtgaaaag cctaaaaatt
    25681 tctggggaac ggtacgccga ttgtttggct atatgtctaa acgtatggtt gcgatcatcg
    25741 ctgtatttgt actagcaata gcagccgtga tcttccaaat ccaaacacca aaggtcttgg
    25801 ggaaagcaac cacagaaata ttcaaaggtg taatggctgg cgctcaacag atgcaacaag
    25861 gccaacaagt aacaaaattt ccgatagact ttgataaaat cgcgcagatc attgcgacag
    25921 taatcgtgat gtatttgatt tctgctgtat tcaacttttt acagcaattt attatgacac
    25981 gtgtttccca acgaacagtt tatgaattac gtcatgattt ggaagccaaa atgaatcgtg
    26041 taccgatttc ctattatgat acacatacaa atggggatat catgtctcga gcaatcaatg
    26101 atatggataa catcgcaagc acgctgcagc aaaatttgac tcaatttgta actagtgcag
    26161 tcacattgat tggggtcatc gtgatgatgc tttcaatcag ctggcaattg acgttagtcg
    26221 cgttattgat gatcccttta agcttgatca tcgtgatgat cgtagcgccg aaatcacaag
    26281 tgtttttcgc agatcagcaa aaaagtttag gtttattgaa taaccaagta gaagaaacat
    26341 atggtggtca taccattgtt aaaacattca atcatactga aaaagaccag gaagtatttg
    26401 aaaaagaaaa tcagaatctg tatgccgctg gttggaaagc tcaatttatt tcggcaatca
    26461 tcatgccgtt gatgaatttc gttaaaaatc taggctatgt gttcgtcgct gtactaggcg
    26521 gagtaaaagt tgcaaatggg aacatgacat taggggatgt tcaagcgttc ttgcaatata
    26581 caacacagtt ctctcaacca atcactcaac ttgcaagttt gatgaacact atccaatcaa
    26641 cagttgcttc agccgaacgg gtatttgaag tgttggatga agaagagatg tccaatgaaa
    26701 aatctggcct tccagaagaa aaagatacac catacaaagt tcgttttgaa aatgttcaat
    26761 tcggctacac accagataac ttgctaatga ctgattttaa cttggatgtc aaacctggtg
    26821 agatggtcgc tattgtaggt ccgactggtg cagggaagac gacactgatc aaccttcttg
    26881 aacggttcta cgatgtttct ggaggtagta ttcgttacga tggtgtagat acccgtgatc
    26941 tttcacgtga tgaattgcgc gcacagtttt caatggtact gcaagatact tggctgttta
    27001 caggaagtat ctatgacaat atcaaatatg ggaacgacga tgcaacagac gaacaaatca
    27061 ttgaggctgc taaagctgct cacgtagacg attttgttcg taaattgcca gaaggatata
    27121 acactgtatt aaacgaggat gcaagcaata tttcgcaagg gcagcgtcag ctaatcacaa
    27181 ttgcgcgggc attcttagca aatccagatg tcctgatcct tgatgaagca acatctagtg
    27241 tagatacacg aacagaaata ctgattcaaa aagcgatgaa ccgcctattg gaaaaccgga
    27301 caagtttcgt tgttgctcac cgcttgtcta caatacgcga tgcagacaac attattgtga
    27361 tgaatcatgg ttcgatcgta gaaacaggaa accacgatac attgatggaa aaagacggat
    27421 tctatgcaga tctttataac agtcagtttt ctgaagaaga agcttcatag aatagtacaa
    27481 atttattatt ttttttaggg gctgtgacaa aagtcgtgtc acagtccctt tttccgaata
    27541 aacggtgttc aatcagctgt ccttcggtat tagctcaaaa aacggcaaaa tatgagaagc
    27601 tatttttccg ttttgtatct ctaatactca ggtcaaaccg ctgattttac aacctcttcc
    27661 ttaaacggtg ttctcctgcc aactcctcgg tcacaagtca caatagtcaa caaacctgag
    27721 aagctgtttt ttgaaattgc tccttgtgac tcggagttaa acggcaggct cacaacctct
    27781 tggtaaacgg tgttcaaaag ccagtttctc ggtattaagc caaatttatg caaaaatgta
    27841 gaaagccatt ttcacaaaat ttttcttact actcgaaact aagcgacttt ttcacaacct
    27901 cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa
    27961 taggaggagc tatttttgtt tggctgttct tattacttga tgcagaacag ctttttcaca
    28021 acctcttttt ataagagttt ttactcatta atttacaaaa aacaagcaaa atgcgaattt
    28081 tctcacattt tttttaacaa aatcaaagtt attgcttgaa agaagaagaa tccatcgtta
    28141 aaataaagct tgacgtagag gggagcaaga aatatgaaag attttcaatt gggggctgcc
    28201 acctatttaa aaagtgtagc cattcgggtg aaagaccgag ataaaatgat tgatttttac
    28261 aagaacgttg ttggctttga tttgaaaaga gaagaaaacg aattagccat tttaggaaca
    28321 gaagaagctg gaagtgaaat gttgctgctg gaagaaagtc ctagagcgaa tgatcacatg
    28381 ggggtgatca aaaagctgaa ccgtttttca ttgattatcc ctagcacaga agaaatggca
    28441 gatatccttt gtcgtatccg taaaatgaat tatccaatca aagaagcttt agaagatcat
    28501 ggacgtatgg ggattttgct cgtagaccca gaagagaatg aattggaaat ttaccatgaa
    28561 gagaataaga acgaccaaag agaaattcca gaaacaatgg atcaagaagc attattaaga
    28621 aaatctgaag aaaaattcag taaactatca acaggttctt attttgaaaa aatccattta
    28681 aatgttacta acttaacaaa agaacgccaa tttcttaatc atgtacttgg tttgaaggta
    28741 cataatgaag aagagggcat ccatgtattg aatgaaggag atttccatgt tggtttgaca
    28801 gaagctagcg gaggcgcaat tgatttgcct acagatgaag tgattggact tgattttctg
    28861 aaattcatga tcgatactga aagcatggaa ggactgattg ctcacttgca gcaactatca
    28921 gttgatttct tcttagacaa aaagcacaca gtactcacaa tctatgatgc tataggaatc
    28981 gaatggtggt tcgtcagtga gccaaaagaa aagaataaaa ctgacattcg atgcgacgct
    29041 taactttttc tttcttaacg attgtcgcat gtctcgtcat tttatgaacg gtcatactat
    29101 cgcttattct agagatagaa agagaaaata gtataccggg ggaaactgcg cggtttttcg
    29161 cgcagttttt ttgtgtaaaa aaggttgatt cctcatagat taagctttaa gcttggactg
    29221 taagaatctg atagaaaagc aggagaaaaa gatgtatcca cacacgaaac agcttatttt
    29281 gaaaaagatg gaagaaggat tttatccagg tgtagcagtc gccttcataa aagaaaatca
    29341 agtagaaaca tttacagccg gctttgccca agtcgttcct gaaaagcagc tgatgacaga
    29401 agatctgttg tttgatgcag cctcactgac gaaagtcgtt gcaaccactt cattagtttt
    29461 acgtctatta gaagatggaa agatagaact cgatcaaccg cttcataaat atcttcctga
    29521 atttgaaaat cagacaatca ctttgcgtca tttactgaca catacttctg atatcaaaac
    29581 atggatacca aacagagata agctatctca ggaagaattg atcgccgctt atttgaagct
    29641 agaaccaggt gagcaactag gaaaagaagt aaaatataca gatgccggta cgattcttct
    29701 tgggttgatg ctagaggaaa tttaccaaga aactgcagtg gaaatctttc aagaacaagt
    29761 attggaacca ttaggaatga tgaacagctt atttcttcct tttccttcca aaaaaatcgt
    29821 tcccacagaa caactgcctt cgggtgaggt tttgcgtgga caaactcatg atccgaaagc
    29881 aagagttttg gctgaacatg caggtaacgc gggtctcttt attgatttga aagacagcat
    29941 tacttttgtc caaatgtatt tgaacaaggg aaaaatccgt aatggtcgtt ttttagaaga
    30001 agagacgatt gattctttac tgcaagatca aacaccgaaa aaaaatggct atcgttcttt
    30061 aggatgggac ttaaaaaagg atgtagaaga cggtcatgcg attctttttc atactggtta
    30121 tacaggtacg tttttcttga ttgatataaa aacacaagaa gcgttgatat ttttgtcaaa
    30181 tcgcgtacat cctgtcgatc atcgtgcgga gtatctcata tgtcgagatg aaattgttga
    30241 aaactttttg aaagagaaag cggtattacc gaaataatgc tataatagct atgaaaaatg
    30301 agaggagttt gaattatgca ggaacctatg tttttaaaac cagtttttca agaaaaaatt
    30361 tggggaggaa gtcgtttacg ttcagtcttt ggttttgata tccctaacga taaaatcgga
    30421 gaagattggg cgatcagtgc gcatcctcat ggtgtcagtg tagtagaaaa tggcgaattc
    30481 aaagggaaaa gattagatga actatggtca gaacacaagg aattgtttgg ccatccttca
    30541 gaaccagtgt ttccattatt gatcaagatc ttagacgcag aagatgatct atctgtacaa
    30601 gtacatccag atgatgccta tgggatgaaa catgaaggtg aattaggaaa aactgaatgc
    30661 tggtatatca tcgatgctga acctggtgca gaaatcatct atggtcatca tgcaaagaca
    30721 agagaagaac tagctgagat gatcaaagat gggcgctggg atgacctttt gaagaaagta
    30781 ccagttaaaa aaggtgattt cttttatgta ccaagcggaa cgatccatgc tattggtaaa
    30841 ggaatcatga ttttagaaac acagcaaagt tctgacacga cttaccgcgt gtatgactac
    30901 gacagaaaag atgcgcaagg acaaacaaga gagctgcata tccaacaatc gatcgatgta
    30961 acaactgtcc ctgcgaaaac accagaatta caaatcaaag aagtccgaaa agggaattca
    31021 tcgatcgtca cttatttaga aactgagttt ttcaatgtat atgagtggga tattaaagga
    31081 atcacatctt tcaaaaaaca agccccttat acattgatga cggtaatcga aggagcagga
    31141 gaccttgtcg ttgacggaaa aacatatcca ttagaaaaag gaacaagctg tattattcca
    31201 aatggcgttt ctgagtgggc ggtccaaggt gaactagcaa tcattgcgtc tgaaccaggc
    31261 aaatagttcc cagatagctg aaagcagcag acggtttttc gtttgctgct ttttctacat
    31321 aaaatccgtc catcaataaa tagaagtctg gtgaaaaaga tggaatacaa atggaaagca
    31381 aacaacagca gtcgcgtgtc tatgaaacaa ctgagaaaag ctggacatca cttaaatgaa
    31441 atgatcatgc caaatctaag tctgtttatc gcttggggaa tcttgtcatt agcaacaaaa
    31501 ggtgtgtctg gcgatttgca caccacatta gaagaggtat gccattggat gatccagctg
    31561 cttttaccca tcttgatcag ttattcaggc gggaaatcgg tagggggaca aaaaggggca
    31621 gtcgccggtg caattgcttc tttagggttg atcgctcgtt ccaatgctcc acaaatcgta
    31681 ggagcgatga ttatcgggcc gcttgccggc atcgtatatg aacaatttgt ttctagattc
    31741 catgtgaaat tcaaggctgg atatgaaatg cttgtcagca acctactagt aggactgact
    31801 ggtagcgtta tttgtataat tggaatcgtt tttattgaac cagttttaaa tagtgttcac
    31861 ttgttgctcg cctccgttgt gtcttggcta gtcacaatga atctgttacc acttgtcagt
    31921 ctgatcttag aacctctaaa agtactattt ttcaataatg caatcaatca tggtgtattg
    31981 acacctttag gaatcgaatt ctcacaaaca gtcgggtact cttccttatt tttgatggag
    32041 gcaaatcctg gacctggttt agggatctta ctttctatcc tttgttttgc agaaaaacag
    32101 gaaaaagtaa atgcgagtgg agcattgatg atccatgcga ttggcgggat tcacgaaatc
    32161 tattttccat ttgtcttgct gcgaccgtat ctatttttag ctgtaatggc tggtggggca
    32221 agcggcacgt tgatatttca atggttagat acgggattag ctgcacctgt atcgcctggg
    32281 tcactactcg tgatttttgc caatgcgcct tatccacaac tagctggggt aagtataggg
    32341 atagcaatca gtacatttgt gaccttcatt tgtgcagcga tactattgaa attaccaaat
    32401 aaagaaaaag agaacaaaac ggtcaaagaa aggggagaaa tcttggaacc atctatcatt
    32461 cattccgtca tttttgcttg cgactcaggt atgggatcaa gtgctatggg agccgccctg
    32521 ctgaaaaaga aattagcagc agaaaaaatc gatctttctg tcggatacag ctctatctat
    32581 gaattgaata accaagtaaa tcagctggtt atcgtgcaac atgaactagc gggtcttgca
    32641 agagaaaaag tacctcaaag tcaaatctat gtactggatc actttttgga aacagatatc
    32701 ttgctgtcac gaataaaaga agcgatccaa tttccaaagc gggaagaaaa aaaagagata
    32761 gcagatatca cagaacaaaa aacgtcgcct gctaatattg tatttttgta taaaaacaac
    32821 agacgcggct cacaaactat gggcatgacg attttaagtc aattagcaaa aaaagcgaaa
    32881 aaacagtttg ttatctcaaa agaatcaata gaaaaaatca aaatccaaga agaaacgatt
    32941 tatatcgcac aaagagaact agctgtaact gaacagctag aagaaaagat ccctcggcta
    33001 gttctagttg aacattgggt agctacgaat gaatacgaaa aactcgtgaa gggagaaata
    33061 taagatgtat ttatcgccca gagaaaaaca attattagca gaatttctca gtagcccgtc
    33121 acctgtatct atccaaaaaa tgatgaattt attgaaggtc agtaaacgga ctatttaccg
    33181 cgaattagat aatcttgaag tctcattgaa atcggtaaat gcttctttga aaaaagcagc
    33241 tagaggctca tttgtcattg aggcatcaga agaagtatta gagcaattaa aagaaaatac
    33301 agatgggaaa agtaatgact tatccactgc taaacgacaa cacgcgattt tagccgagtt
    33361 gttactgacg acagagccgt tgagtcttgc tcatttcatg gaatcatatc gcatcagtaa
    33421 taccactttt tatgcagata tcaaacagtt ggaagaaagt attcgccaac tgcctttgga
    33481 aatcattcgg aaccagggat acgagatcga aggaccggaa aaataccgcc ggcttctgac
    33541 agcgaatgta ttagaattag aaatcaatga atatgaactt tttcatagta tttctttcga
    33601 tgcatcactg aattattttt ttcgattcgt tgatccgcaa catctatctc ttgcacgcaa
    33661 agtaatcggg gaagaattga tccaaaaaaa gaccaatcta agtgatagaa agcttgaaca
    33721 tttggttttg atgctgacat tgacgatgga gcgtgtgacg aaaaatcatt tactgacaaa
    33781 tgagacatat aatagtctgg caaacaaaga attactacag acagctaaac gattgttttc
    33841 acggatcgct tctgagacaa aacaacttta tccagtaaat gagatcgtct tttttgcagg
    33901 attattaaat gacttcacga actcatttga tcagaatttc tttgaagaga cgttcgatac
    33961 acagcttgct tatttagtaa aacaactgat tcaagaagta agtgaagaga cgaatgtcca
    34021 tttttatgaa gatgaaactt tgtacaaaat gctgttgact catttatctg gtgtgttttc
    34081 aagagccgtt ttacaagaag agacactgac caatccgatt ttagaaaaaa tcatggttca
    34141 atacgaggaa gttgcgaatg caatccgtaa agcagtagag cggatttttc aagaaaaaaa
    34201 attatccgaa gaagagatcg cttatatggt ccttcatttt gcgaattcat tggaacgaag
    34261 tccgaaagaa agcaatatca gtattgcagg attttcgcca agtggattag cttctactag
    34321 catgttggaa ctacgattga aaaggtattt tcccttcatc caacaaattc atttctatcg
    34381 gattgctgat ttaaaaaaaa tcgatttaca agaagaatat gatgttgtta tttctacatc
    34441 tattttacca ggatacggtg gaaaatatat tttagtctcc ccgctactgc tagaagatga
    34501 agtcaagcag ctaaaagaag ctttttcgca tattgagaag aaaaaaaggc aaaaaattac
    34561 gtataacagc aataacgagt ggatgataga agatacttat gaggaaacaa tgcatttcat
    34621 ggatcaaatc aatcaattac tcggtcgttt ttttatccaa gaactggata atcctgagac
    34681 gatttccgaa acgattcgca gcttatttcc ttattttcct gaaggactag taacggatga
    34741 agaggtggtt catcgccggc tgcttaagcg atatgaacaa gcacctatcg gtattcctca
    34801 tacaaatatg gggttattcc atacatccag ctcattgatt tctaaaccga tcttttgtat
    34861 tttcaatttg aaacatccgt tgaccattga agggatggat agacagccag tcgatttgtc
    34921 ccgtatgtta gttatgctgg cgccttcgcc aatccaagaa aaagacggga ttcttttagg
    34981 aaagatcagt ggagcaatca tcatgaatga cttgaacacc gagatcttcc gctcaggaaa
    35041 taaagaaatc gtttatcagt tgttagcgaa aatcctgatt gaagaaataa agaaatgaag
    35101 gtgaaaagat gatacagcta ccagcagaaa aaatattgct cgatcaatcc tatcaaaatt
    35161 ggaaagaagc gttgaccgag atcggccagt ggatgaccca acaaggggga atcaaaccgg
    35221 catatatcca atcaatgatc gaaagacaag aaaaagcgag tgtctatatc gggaatttcg
    35281 tagccttgcc acatgggact gacaaagatg aagaagtagt agaagaagga atctatttag
    35341 tccaagtgcc tgatggtgtg gactttggaa caaaagagga accaaaaatc gcgacactct
    35401 tatttgtagt ggctttaaaa aaagaacatc agttagcggt gctccaagat ttagcctttt
    35461 tctgttcaga catcgaccaa gtaatggcgc tcagtgatgc ggaaaccatt gaagaagtcc
    35521 aaatgatttt tgaacatgga catatataac caatgttcac agtaaaaaaa gctgccttgc
    35581 atcaagtaat aacttcaacc aagataaaaa taagaggagc tatttttgtt gggaggttct
    35641 tattactgcg gatgcaagct tttgaaaact atttattcta gaaaaccgtt tatttgaaat
    35701 aggggacggt gacaaggttt ttgtcaccgc ccctattatt tttgtgtttt aatagctctt
    35761 ttttatatag atagtgccca tacctatgaa taataaaacg atactccata taccaagtgt
    35821 caagatacca ttcatgaaag taacctgttc tgaagctagt ggcgagaaaa tatctcctcc
    35881 tatgatcaca ttttgaaaat caacataaga agttggcaag taatgactga ttgattctat
    35941 ccatccaatc gaagaaaaca agcgatactc tgctaagaaa agacaaagaa gtgtacctaa
    36001 aagattgact agagaatgtt caaataaagc agatagaaga aaactgattg tacttaaaaa
    36061 gagcacccac aacaacagga acagaaagct ctggaaaaga tactcataca tcggcaggat
    36121 tcgtatctcc tgaccaatga tcgttcctac aggataacgg aagtctccca aaccattttt
    36181 gattattact agtatagaga cgatcaaaaa tggcatcacg agacttagca tagctgcacc
    36241 ataataaatg gtaaaacgga tgctatgttt ctttaccata ctatccagta atagattgac
    36301 tagagagatt acctgctttc ttttttcata agagatgatg gaagaaagaa acaaggcggt
    36361 tatacataaa atcaaaaaac tagaaatcat tcctgaaaaa atattttcgt agtaatttgc
    36421 taaagagaga tgcgctggca agtcaaaaat agaatatctt tggatctgat gttctttcat
    36481 ataacggagc aactcgacac gtttttgttg ttcaatgatt ggaattcctt gtctttgacc
    36541 agaaatcagt cgatccagta tatctttttc ataatgataa gttgcttcga ccatttgctg
    36601 gacattccct gtgttttttg catgtaagat tgcttcgatc agtttgttgc ttttctctaa
    36661 actttccaca aattctttct cattctcatc ttctttcaac gtttcaatca aacgttgcat
    36721 ctcttcatag ttatgattca gttcatcgaa ttctgtataa gcaagtttat gatcaaaaaa
    36781 aagtgggaat gcaaagagca cgaccaacaa tagaggaaat aaaaagttta ctttgttttt
    36841 tagtaagaga ttgcgttcaa atgtaagtaa agacatagtt acacctcata taatttacga
    36901 taaatagcta aaatctcttc catatttgag gattctgtga cgatttctcc attttttaga
    36961 aaacatgctt tagaacaaat cgattggata ttcgcgatag cgtgggaaga aagaagaatc
    37021 gtcttcccct ctttctgcca ttgtctgatg aggctattca agatatcaat acttcctggg
    37081 tctaatccgt tcaacggttc atcgaataac atgacagatg aatcactgat caagtaagca
    37141 gcaagcaaga catgttgttt cattcctaga gacatttttc caatcggcaa agtaaggtac
    37201 tcagtcatct tcaatcgttg gaaaacagtt tggcattcta ctttgctctg ccaatagtat
    37261 ttgatcaaag tcaaataatc aacagccgat agatagtcgg ataactgatt cgttgattct
    37321 agaaaaaaga aagaccggcg ataatctgta taagcagtag gagagatgtt gtgaagggac
    37381 aattgatcat aagttgttgg cagcagttgg gcaatgccat tcagcaaagt tgttttgcca
    37441 aatccgttcg gggcaatcaa agcagctact tctcctgatt ctactaaaag attcaattgt
    37501 cgaatcacac gttttttacc acgtttcatg ttcatgtttt tgatcagtaa tgtcatagat
    37561 aggcctccaa tataaaattt aataacataa tagaatggaa aacatctaaa ttaaatgcta
    37621 acaaaagtta ttgtttgcat attataaaaa aattaaaata acagttttat ttaaaattga
    37681 agttttctga taccgaaatc tttttatttt gctgacatac tcaaaccttt ggcacaaagt
    37741 ttcgtgccaa agtacgacta tttctctttt tagtaagcgg atacaattag agtatcaaaa
    37801 ggagagaggg agagacaaaa tggaacggac gattcccaaa aacaacattt cgctaaaagc
    37861 gagggtacaa aaattaggca gtactttatc aagcatggtc atgccaaata ttggagcact
    37921 gattgcctgg ggtgtattaa cggctctatt tatcccagat ggttatttac caaatgaggc
    37981 tttcgctacc atggtaagcc caatgctaac ttatctgatt cctttattga tcggttatac
    38041 tggcggaaaa gtaattgctg gtgaccgcgg atcagttgtt ggggcaattg caacgatggg
    38101 tgtgattgtc ggaacagata ttccaatgat gctaggcgcg atgatcatgg gacctcttgg
    38161 tggatatgcc atcaagaaat ttgatcagct attccaaaaa cggatcaaat ccggttttga
    38221 aatgctagtc aataattttt cagcaggtct tatcggtttt ggattagcgt tattaggttt
    38281 ttctgcgatt ggtccagttg tcgatgcatt gactcaagca atggcaaaag gtgtagagat
    38341 cattttatct gcccatttga ttccattgac aagtattttt attgaaccag caaaaatctt
    38401 atttttgaat aatgcaatca atcatgggat tttgacacca ttgggaactg aacaagtagc
    38461 agaggctgga aaatctattc tattcttgct tgaagcaaat cctggtccag gacttggcgt
    38521 attacttgct tttactttgt ttggcaaagg agcagcaaaa tcttcagcac caggagccat
    38581 gatcattcac tttttaggcg ggatccatga aatctatttt ccttacgtta tgatgaaacc
    38641 gttattattc ttatcagtta taggcggagg aatgtcagga agtttcattt tccaattgat
    38701 ggatgctgga ctaagagcgc cagcttctcc agggtcgatc attgcgattc tagcgatgac
    38761 accgttcaat tcttaccttc ctgttatttt gggcgtgatt gttgccgcag ctgtttcgtt
    38821 tggtatttct gcagtaattt tgaaagcgga tgcgaaagat acaaatgaag acttcgaaaa
    38881 atctgttcaa gagacaaagg cagctaagca agcttccaaa ggtgcccaag gtattcctca
    38941 aggagctaca ttctctggcg tacaaaaaat catttttgct tgtgatgcag gaatgggatc
    39001 aagtgcgatg ggcgcttcga tcttgagaaa aaaagtacag gaagcagact tgcctcaaac
    39061 ggtgaccaat caagcaatca gccaactgac agatgactcg aatacattga tcgttactca
    39121 ggtcgaacta caagaaagag caaaacaaaa agcaccgagc gcgcgttttg tctcagtaga
    39181 aaactttttg aattcacctc gatatgatga aatcattcaa gaattaagca gcaagcagaa
    39241 aacatcagtt tctgaaattg agaatgagcc agcagaagag tttctttcag caaacatcaa
    39301 acaaatcaaa gagattctac ttgtccacga tgatcgttcc ggatcagcaa caatggggat
    39361 gaccgtgctc aaagatatat tagacaagaa ccatttaact atcccgttaa gaaaagtcaa
    39421 tatccaagat ttaaaagatg aacctgattc actgatcgta gccaaagaaa gtttagcgga
    39481 aaaagtacag atggctgcac ctcaatccat tcatttatca gtcaacagca tggtcaatcc
    39541 gcaaaaatac gaatcgattg cacaatattt gaaacagaca gcttaaggga ggaaaacagc
    39601 atgcaaagtt tgccattcga catgatcgag ctcaatcgat cttttaaaac caaagaagaa
    39661 gcgatccgct attgcggtca gatgcttgta gaagcagggt gcgttgatga ggaatatatc
    39721 gatgccatgg tagatagaga caaaatgtta tctgtttata tggggaattt tatcgcgatt
    39781 cctcatggaa cagatgaagc aaaaaaatat gtgaaaaaat ccggcatctg tgtcgttcaa
    39841 gtaccagatg gtgtagattt tggtaccgaa gaagaagaaa agattgcgac tgttttgttc
    39901 ggtattgcag gagtcggaga tgagcatttg caacttgtac agcaaatcgc actttattgc
    39961 agtgatatgg acaatgttgt ccagctagca gacgcgctca gcaaagaaga agtaacggaa
    40021 aatctagcaa ttgcttaagg agagagaaaa atgagagcag tacattttgg tgcaggaaat
    40081 atcggtcgag gatttattgg agaggttttg gcagctaatg gatttgagat tactttcgta
    40141 gatgtgaatc acacgatcat tgatgcttta aatgaaagaa aagaatacga aatcgaatta
    40201 gcagatgaat caaaagaaaa aatcactgta aaaaatgtca aaggaatcaa caatcaaaca
    40261 aatccagaaa aagtaatcca agaaatcgct gaagcagatt tagttactac cgccattggc
    40321 ccgaatatct taccttttat tgctgagttg attgcaaaag gtatccaaga aagagaaaag
    40381 gaaggaagca caacatcttt agatatcatt gcctgtgaaa atatgattgg cggttcagca
    40441 tttctagaaa aagaagtgta taaatatctt ccggaaacat catttactga caaatatatc
    40501 ggctttccaa atgcagcagt cgatcgaatc gtcccattac aacaccatga agatccttta
    40561 ttcgtccaag tggaaccttt caaagaatgg gtcattgacg atagccaaag aaaaaataaa
    40621 aaaatccaat taaaaggggt tttatatgta gatgatctag aaccatatat cgaacgcaaa
    40681 ctatttagtg tcaatactgg tcatgcgact gtcgcttata caggtgcctt gttaggttac
    40741 cagaccattg atgaagcaat gcaagatgcg ttagttgtgg cacaattaaa atcagttttg
    40801 caggaaacag gaagtttgct gattgccaaa tgggggtttg atgcagagca gcatcatgcg
    40861 tatattgaaa aaatcattca tcgcttccaa aacaaaaata tctctgatgc gatcacacgt
    40921 gtcgctcgga caccattacg taagttaggt tatcaagaaa gatttacacg tccagtgaga
    40981 gaactacaag aacataactt gacttgccca catttgacgg caacaatggg gattattttt
    41041 aattactatg atcctgaaga tgaacaaagc cgtcaattgc atgaaatgaa gatccatgaa
    41101 aacttggaac aattgattca agaagtcaca ggaatcaatg atccgaaaac aatcgggaat
    41161 atcaagcaaa acgtgaaccg ttatgccaag caagtcgctt aaaataggat acgaaaaagg
    41221 ggaatgtgac gaaatttttg tcacattccc ctttttcgaa taactaggct gtttgtcctt
    41281 caagataggg cagatccaat tctttaccgt aacgttgttc taaagctagg cggatcaaac
    41341 gagctgccag gttctcattt cttgcaagga taggtccatg gaaataagaa ccgaagacat
    41401 ttcggtaaat gacaccttca gattggtctt caccattatt tccttgacct tgtaccactt
    41461 tccccaaagg tcgttcacct tcacctaaga aagtccgacc attgtggttt tcaaatccat
    41521 aataagtttc attgaattct tcgttatgga taacgatatc accgataaac cggttatttt
    41581 cctgacttaa cgtgtagtga tccagtgcac tgattccttg gatcttttct ccattagctc
    41641 ccatgtagta gtgacctagc aattggtagc caccacaaat ggctaacatg acgccatcat
    41701 tttcgatata gttgatcaaa gaatctttct ttttctggat gtcttttgaa atgattaatt
    41761 gctcaaagtc ttgaccaccg ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt
    41821 catgtatact aacgatctcc gtatggcaag aaacccccat tttttctgct atatatttca
    41881 acatcaaaag gtttccgtta tcaccatatg tgttcatcaa atttccataa aggtgggcga
    41941 tattgagttc ataattagcc acggttcatt cctcctttga taaatccttg agcagctagt
    42001 tctttacgaa gctgcaatac agcagtgtaa gtagctaaaa tatagacatg ctcagttggc
    42061 aattctttga ttttttcgat tacttctggt aattcttttg tttctgtcaa tttattttct
    42121 ggaatcccgg caacttttag acgtaaagtc atatctgtat gacggtctcc tccagaaata
    42181 acagctggga tatccatatc ggcaaagttt tcaaaattac catcccaaat ccagctgaca
    42241 tcgattccgt ctgcgtaatt ggcatttaat aaagccacta aagaaaatgg ataaggagct
    42301 agaccaatca tatcgattac ttgattgata cctacaggat ttttgacaag tactaatgta
    42361 cattttttcc cattgatatt gatgacttct tgtcggccga atactttctc gtcatatcct
    42421 aaaccttgtt tgattttatc aggatcgaca ttgaagtact ctgccactgc agtagctgct
    42481 aaagcattgt agacattata cataccgcca acttcgattc cgtattcatg accatcgatc
    42541 acgaaatctg ctgacacatt gtccatccgt accatatcag ttaatcgata atccaattca
    42601 ggacgtttga agtcacaatt tggacagtaa tatttcccta agtttgcata agtgatcatt
    42661 ttataatgca agatgtgatg acaatttgga cataagacac cgtctgtatt gtaatgagcc
    42721 atttgttcac gatcttcttc atggtcaaag ccataatatt ttctaggatt gactgtttcg
    42781 atagaattga agattggtga atcaccgtta ctgataatcg ttgcatttgg tgactttgcg
    42841 gcaccgtcta caatcatttt ataggtcgta tagatttctc cataccgatc catttgatca
    42901 cggaaaatat ttgtaaataa gaacagttct ggtttcatat attctgtgac tttgctcaaa
    42961 cttgcttcat ctatttctag gacagcaaac tttttctgtc ctttttttgg ttttgcctgc
    43021 aagaaagtcg atacaattcc ctgtaccata ttcgcaccag tagggttggt tagaacttca
    43081 tcgaattgct ggcgcaaaat attgactgtt aaagcggtag tcaatgtttt accgtttgtt
    43141 ccggtgacaa cgacgacttg gtagtctttt gccaaactat ctagtatatg tggatcgact
    43201 ttcagcgcta gtttacctgg taaacttgat ccgcctttaa aaaaagtttt taatgcccat
    43261 tgcgacgttt ttccaactgc aatcgcaaaa tgactgcgta ttcccattat gtaacctcca
    43321 aaaacgattt gctgacgaat aaattcaact aatcatacca tatgttgaaa aaaaggttaa
    43381 attgcttttc ttattcttaa gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat
    43441 cgcatgattt aacaaaaaaa cagcttgaaa caaaatgatt gtttcaagct gctgtgattt
    43501 tattattccc tcttacctat attcccattt taaccgataa taattttctc gcttggatat
    43561 tcatagccta gatctcgtgt ttcttttggc acgaataaca tcaatgtata tagcattccg
    43621 atccgcccaa taaacatcag tgtagcaatc gtgattttgc ccacaacaga caagtctccg
    43681 gtaatcccta aagataaacc agttgttcca aacgcagaag ttacttcgat gatgatcgag
    43741 atcagcgttt gttcttctgt agcagataaa aaaacgatac aaaagaaaca cataccaaga
    43801 gaaagcataa agacaacgac tgattttcgc acatcatctt gatcgattct ccgtccaaaa
    43861 atattgatgt tatcttcact tttgaggaag gaatatagat acaaaccgat gattgctaca
    43921 gtagttgttc gaatcccgcc gcctacagaa ctaggactgc atccgataaa catcagtaaa
    43981 gaaaaaatga tcagtgttgt gatttgaaaa tcacccaaat cgtgaatctg cagaccagca
    44041 ttacgagtcg taatcgaata aaacatcgaa ttgatccatt tgacactcat attggaatct
    44101 tggaataaat ggtccttttc caatagataa atcaagacag ttcccgaaac aaacaagata
    44161 acaaaagcta acacagctaa tttggtaaac aaggaaaaac gaaacggaag cttcgcattg
    44221 gaacgtttgt ataatagcca ttcccggcac tccatcaata caggaaaacc aattcctccg
    44281 acaaaaatca aaaacatgat caggatcaag aaaaaatagt catgtgcaaa gggcttgatg
    44341 gaatccccag tgacgtcaaa cccagagttc gtgacagccg atatcgcctg ataaaaaccg
    44401 taaaaaacgg catcacgcca acgatcaaaa tagcctctgt aataaaaata aatagaaaag
    44461 aatgtcccaa aaagtaattg aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg
    44521 acgataccag acaaacgcgg ttgattcata tccgtcatga tcagctgtcg ctgtttcagt
    44581 gtgatccgtc gtttagaaaa aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca
    44641 ccaacttgaa ataatatttc cagcagtata ataccgttat cattgaacac agaattgata
    44701 tcaaaagtcg atagtccagt cacactcact gtactgattg ccatgaacag catgtccaca
    44761 aaagaaacat ggctatctgg ttcgcgaaaa atcggcatat aaaatagaac gagtgataag
    44821 accgtcatca atatataata aaaaacgatg atttggatcg atgagaaatg attggcagca
    44881 aacttctgtc ctcgccgctg cagccttcga aagaataaat caacatgcac agtactatcc
    44941 tcctgacaat agtcgtttct accagtatac aaggggaatt aggaatactc aaagaaatta
    45001 tcaaacagat aacaatacag ctttcgatta aaatagaaat ggcttataat aaggaaaatc
    45061 ctagaaaaaa gaaggaggag gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa
    45121 atgaaaaatc aaaaaataaa ttatgataca gttctgaaaa aaatgatcat gcaatgggag
    45181 aaagaagaag taaagcctaa gatattaata catacatgct gtgctccttg cagtacgcac
    45241 acattggaat tcatgtctca atatgcagag atcacgttat ttttttcaaa ttcgaatatt
    45301 catcctaaaa gtgagtattt gcgaagatta catgaacaaa aacgatttgt agaccaattt
    45361 aatgagaaaa ctgaccatca tgttgcgcta atcgttgatg aataccgtcc aaatgaattc
    45421 accaaaatgg ttttaacaaa ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt
    45481 gcatgcttca atatgcgatt agatcttgtt gcgcaaaaag cgcaagaact aggatacgat
    45541 tactttggaa gtgccctgac catctcgcca aagaaaaatg cagctttgat caatcagatc
    45601 ggaatggata tccaaaagat ttacgggaca caatacttgc caagtgattt caagaaaaac
    45661 aaaggctatg aacgctcttt gcaaatgtgc aaagagtatg atatttatcg ccaatgttat
    45721 tgtggttgcg tgttcgctgc caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa
    45781 gcaaaagctt acttaaaaac atcaaccgta gtttttgagg aaaattaaag aaatctttcg
    45841 gaaaaacgta agaaaaaaat aaagaattta tggtagaaat aaggtagact gtataatttg
    45901 tccgtagtaa agtaaggaaa caagaataaa tttcaatgaa ggaagagata agatgcgaaa
    45961 agtagcacct attttgaagc caatcgctgt attaacaatc tcgacgattg tcgcgactac
    46021 tacaggtatt gtgaatagtt ccagctaccg tgcaccaagt tcaagttcta gtactgtaga
    46081 agaaacaaca ccaactactt cagtctcgac atctgaacca acaacaacgg aaagtttgaa
    46141 tgaaaccact acgacaagta catgggacga tacaacaact agttcgtcgt atgatgagac
    46201 atatacaact gacagctcaa gcgaaacaag taatacggta ccagatggca ctccatcgga
    46261 ttcaaccaat ccaagtacaa gtccggatac aagtgctagc tccgaaacga taccaagcag
    46321 tacgactgta gatgataaca cgcaaaatga tgatgcagca cgtacagcac agcaaaacca
    46381 agattcagga aatacccaaa cgtataacca gcaagcaggt gattctcaat gacattttta
    46441 ctagacctta tcaacggggt gcataaattc cttggctatt tagacatcag tcctaaatat
    46501 cttaaccgtg gatatacgat tttaagtgtg attcccacgc tttatttatt gagaattgtt
    46561 tatggacttt ggcaaaacca aaactatctt caatttttct tatatggact tgcatttcta
    46621 gtgcttgttt attttactgt tttaaatgta ttttattact ttttagataa aaacacgaaa
    46681 gccgatgtca ctcagctttt tgtgaagtat ttacctgatg aagcgttcaa catccagaca
    46741 gaagaatcga tagataatgg aaattcgatc gataaagtga atacacaaga ggtcatggtt
    46801 tcttatgacg aagattatca attgaaatta gccgagaata tgcggtattt gattggaaat
    46861 ggtgagatca aaacaaatga actcggtcgc atggatggat ttctggtcga tagaaataca
    46921 ttgtatcctt attactatgt caagaaaaca ggagagaaag agtatgttct aaatattgga
    46981 cgaagctact cggacatgga aaaagtaggg accattcgac ttgactcaac agaagacaca
    47041 ttggaacctg tcggattgtt catcgtcggc ggtgattttg tcaaagacgg gttacgctat
    47101 catgagcctt atcgtctgaa attgattgca aaaaaggcac agtcgcagga agaaccagtg
    47161 gtttatagtc gtagccaaag aagaagacat tcataatgtg atgaaacgcc gtgtatcagt
    47221 ggttgcgata aaaacgttta ttcggaataa gggggatgtg acacgtcttt tgtcacgttc
    47281 cttttttata taacgagaaa gataagacga acacatcact tattctttcc tttcatttat
    47341 aaacattgta gaataaagaa agtacaacga agtattgtga aaaaacgtaa taaataacga
    47401 ggaaaataca agtaggaggt aagctgtgaa agaatttttg aaaaattggg ggattttgat
    47461 ccttgtatta gcggctattt tattagctag agtgtacgtg tttacaccag ttactgtaaa
    47521 cgggcattcg atggacccta cattaagtga tggacaacga ttgatttcat ctaagatctc
    47581 aaactatgaa cgaatggata ttattactac aaaggaaccg ggggatgaag aacggatgat
    47641 tgttaaacgg atcatcggta tgcctggaga tacagtcaag atggaaaatg accagttgac
    47701 cattaatggc aaaaagtatg atgaacctta tctggatgag ttcaaaaaag aattttcaga
    47761 agataagtta caaggagaat atgcttatag ctcaggattc caagcacaag cagaaagttc
    47821 atccaccttt acgagtgact ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg
    47881 cgataaccgc ttgatttcaa aagacagccg aatgtttggg ttagtcgaca aagatatgat
    47941 ccaaggaaaa gttgttttcc gttattggcc tctttcagaa attaaaatca tgtgatgaaa
    48001 aaataaaaag aagctgtgac atgttttttg tcacagcttc tttttccgaa aattccttct
    48061 tatttcttgg agttgctcac tttttttgca atctcatttt aagctttttg gctgatggat
    48121 aagaaaagcg aagcgttttt gttcataaat agcttttccc cacgatggaa ggtatgacta
    48181 gtagcagaga caaagcccgt tttttccaat cgattattca attcttcttg gctaaagcca
    48241 ttatggactt tcggatgact aatttgttca ttcttgtcaa agtctacgat gatcaattga
    48301 ccgccaggag ctaaaatttc ataaagtttt gtaagaatat tctccgtatc aggaatgtgt
    48361 aaaagtacaa gtgatagaag gatgagatta gcttggacag caggaaattc gacagaagca
    48421 tcagcgtgga tcgttcggac atttttcaga tctgctgctt ggatcttttc ttctgccatt
    48481 ttcagcatag tttctgaagc atcggcaatg atcagttctt tgaatctttc cgcaagcggt
    48541 aaactaacaa gcccagttcc gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc
    48601 ggtagataag tagttagttc ttcgcgaata atcttggcta atgcttgacg gtcaggggaa
    48661 tcataatggt tagcgatgga atcaaaaata ttttttgtca tcaaatagct ccttacgtaa
    48721 aactttgaaa ttttaactta ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat
    48781 tcaaaaaggg agaatctaga aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa
    48841 aaggaaagtg tgtccgagaa atattactag acttgcctga gtggtttggg cttcctgaat
    48901 caacggaaaa atatatcgag gaatcaagta aactaccttt atggtgtgaa aaaagaaaag
    48961 aagaatattt aggctttatc actctttcac agacaagtga agatactgcc gaaatctatt
    49021 ctattgtatg ggaataaaaa aagactatca tcaccaagga ttaggaacaa aactttttaa
    49081 agaagcagaa ggttacgcag caaaacatta caaatatttg caagtgaaga ctgtagacga
    49141 ggggcactac tctatatatg atcaaactat ttgtttctac gaatcattag gattttcaag
    49201 gttggaagtt tttccaaatt tatgggatga atggaaccca tgtttagttc ttgtcaaaaa
    49261 attggaacaa aagtgagcaa tagatttaat actaatctgt gcttgatgaa aattctcact
    49321 gtaaaaaatg ctgaaaatca agtataatac cataggaaca aactggaagg tgaaaaagag
    49381 catggcacaa ctatttttta agtatggcgc aatgaatagc ggcaagacga tcgagatcct
    49441 aaaagtcgca cataattatg aagaacaaaa taagccagtt gtcttaatga caagcggtat
    49501 tgatacaaga gatggtttag gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat
    49561 gccgatattt gaagaaacag acgtatttga cgtaattcag aaaatggaaa gcaaacccta
    49621 ttgtgtgctg atcgatgaag cgcaattctt aaaaaagaaa catgtcattg cttttacgag
    49681 aattgtggac gaattggata ttccggttat ggcatttggt ttgaaaaatg attttcgaaa
    49741 cgagttattt gaaggatcaa aatatttatt gctttatgca gacaaaatcg aagaaatgaa
    49801 aacaatctgt tggttctgcc acaaaaaagc aatcatgaat ttacattata ttgatggaaa
    49861 ccctgtttat gaaggcgatc aagtgcaaat tggcggaaat gaagcttatt accccgtttg
    49921 tcgaaaacat tactttcacc catcaatgat tacagaagga gaataagcat gtacgatcaa
    49981 ttacaagcaa ttgaagaccg ttatgaagag cttggagaac ttttaagtga cccagaagtg
    50041 atttctgata caaagcgttt tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca
    50101 gtcgaagttt atcgtcgtta taaagaagta gtacaaggaa tcaccgatac agaagaactg
    50161 cttggtgaaa aactggatga tgaaatggct gaactagcaa aagaagaatt atctgaatta
    50221 aaaaaagaaa aagaagtctt agaagaaaaa atcaagatct tgcttttacc aaaagatcca
    50281 aatgacgata aaaatatcat catggaaatc cgtggagcag caggcggaga cgaagcagca
    50341 ttattcgctg gcgatctttt caatatgtac caaaagtatg ctgaagcaca aggctggaaa
    50401 acagaagtga tggaagctaa cgttaccgga atcggtggat ataaagaagt gatcatgatg
    50461 atcaccggag acaacgtata ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag
    50521 cgtgttcctt caactgaatc gcaagggcgt atccatactt ccaccgcaac agttgtcgtg
    50581 atgccagaag ctgaagaagt agagatcgat attgaagaca aagatatccg tacagatatc
    50641 tatcatgctt caggtgctgg cggacagcac gtcaataaaa cagcatctgc tgtacgtttg
    50701 actcacttac caacagggat cgttgttgct atgcaagatg aacgttctca aatcaagaac
    50761 cgtgaaaaag caatgaaaat cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca
    50821 caaagcgagt atgatgccaa tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg
    50881 atccggacgt ataatttccc gcaaaatcgt gtgactgatc atcgtatcgg attaactatc
    50941 caaaaattag atcagatttt agcagggaaa ttagatgaga tcgttgatgc attgatcatg
    51001 tatgatcaaa catcaaaact ggaagctatg caaaatgggt aaaatgacct atcgagaagt
    51061 cctgtcacgg gcttcttctt ttttagagga tcatgggaaa gaagcatata gtatccaatt
    51121 tttatttttg gaacgaaaac aatggaaaaa acttgattgg ctccttcata tgaacgaaga
    51181 gatttcagaa gaagaacagc ggttgatcga aaccgatctg cgacttctgc ttgcagatca
    51241 tccacctcag tatttgctag gatatgcaga tttttatgat catcggttaa aggtaactga
    51301 agcaacactg atccctcgac cagaaacaga ggagttagtc gaatggtgtt tagacgagac
    51361 gcctggtgta ccgttagaag tgatagatat tgggacaggg actggagcaa ttgctattag
    51421 tttgaaagca gcaagaaaaa attggcatat atctgctgtg gatctttcag aagaagcatt
    51481 agaagtagcg aaagaaaatg ctcagaaaga aggaacgaaa atcagttttt atcatggaga
    51541 tacattagga ccagtaatgg atcagcaatt tgatgtgatt atttctaatc cgccgtacat
    51601 cagtcggaat gaatgggaac tgatggatga aagtgtccgg tcattcgaac ctaaaatggc
    51661 cctttttgct gagaacgatg gattagctat ttatgaaaaa atagcagttg aagcaccaag
    51721 cgtactaaaa tcaaatggaa agattttttt agaaatcgga tttcgccaag gtgaagcagt
    51781 aaaaaaaata tttcagcaag catttccaga taaaaaagtg gcgataaaaa aggatctttt
    51841 tggcaatgaa cgaatgatcc aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt
    51901 gtttttttat tataaaaaaa cacttatttg acaaggatgt aaacgacttt ttggtttatc
    51961 aacaagttta tccactattg acaaatagat tatccacaaa cagtggaaaa cttgaggata
    52021 aactcagaca aaataagaat gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac
    52081 gatatgatga aacagaattg caagaggcag ccgaagcact gaaagaagga gaacttgttg
    52141 cttttcctac cgaaacagta tacggattgg gcgccaacgc tcttttacca aacgctgtca
    52201 agaaagtgtt ttctgtaaaa gggagaccgc aagataatcc attaatcgtc catgtcgcct
    52261 cttttgaaca agtaaaagag tatgtggaca actttcatcc ggcagcagag aagattgtga
    52321 agaacttctg gcctggacca ttaactttga tatttaagat caaaaaagac actttgccct
    52381 cagttgtgac gggaggatta tccacagctg catttcgtat accggataac aaaaaaacac
    52441 tagaagtaat cgaactttcc ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa
    52501 aaccaagtcc aacgactgca gatcatgtat atcatgatct acaaggaaaa attaccggga
    52561 ttattgatga tggagctacg cgaattggtg tagaatccac tgttcttgat ttaagtgatc
    52621 caacagccat gcctatgatt ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag
    52681 tcatcgaatc tcctgttgct attgatcagc atcttgtaaa agaaaatgaa acaccaaaag
    52741 cccctgggat gaaatacaaa cactactcac ccgatacacg tgttctgatg gtcagagatg
    52801 gcgattggtc aactgcagtt caatgggcaa aaaataagaa gatccgtgca ggtgtcatag
    52861 caagccccga aattgcggat caagtgcgga cagatactgc agctgtttat atgtataacg
    52921 acaactcagt agaagcggcg gctaaaggat tgtttgcagg tctaagagga ttagatgaac
    52981 caacacttgg attagatttg atttttgtac aagtgtatcc agaaactgga ttggggaatg
    53041 cttacatgaa tcgcttgaaa aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg
    53101 gttattgtcg cattctttta gtatgataca atgctatcaa gtaaatcttc tatcagtgaa
    53161 cgaaaaacta agcgtaacta atcgtaatag aagagatacg aatatttggc aatttgtttt
    53221 tgatgggaaa aataaaattg taggaaaata aaattgtagg aaaataaaaa ggagctgttg
    53281 tttgtggtag attacaaaac gtttgaccct gatctttggg ctgcgatcgc caaagaagaa
    53341 gaaagacaag aacataattt ggagctgatt gcctctgaaa actttgtctc cgaagcagtg
    53401 atggctgcac aaggaagtat cttgacaaat aaatacgcag aaggttatcc agggcatcgc
    53461 tattatggtg ggtgtgaatt tgtcgatatc gttgaaaatt tagcgattga ccgtgcaaaa
    53521 gaattattcg gagcgaaatt tgcgaacgtc cagcctcact ccggctctca agccaacacg
    53581 gctgcttatc tcgctttggt agaaccaggg gacacgatct taggaatgga tctttccgca
    53641 ggcggacatc taacacatgg atcaccagtc aacttcagtg gcaaaaccta tcactttgtt
    53701 gcttacggtg ttgatccgac aacagaagtt attgattata atgtggtacg tattttagct
    53761 agaaaacatc aaccaaaatt gatcgtagca ggtgccagtg cttacggacg aacgatcgac
    53821 tttgcgaaat tcagagaaat cgcagatgaa gtaggcgcaa aactgatggt agatatggca
    53881 catatcgcag gattagtagc agcaggactt catcctaatc cagttcctta tgcagatatc
    53941 acaacgacta ccactcataa aacattgcgt ggccctcgag gcggcatgat tttgacaaac
    54001 gatgaagcat tagcaaaaaa aataaatagt gcggtatttc ctggtattca aggcggccct
    54061 ctagagcatg tgattgcggg taaagcagta gcattcaaag aagcattaga tcctgcattt
    54121 aaagaatata gtgaacaaat catcgccaat gcaaaagcaa tggtcaaagt tttcaatcaa
    54181 gcaattggaa ccagagtcat ttcaggggcg acagataatc atctgatgtt gatcgatgtt
    54241 cgcgagttag gtataaatgg aaaagaagca gagagcattt tggacagtgt gaatatcact
    54301 gtaaataaaa actcgattcc ttttgaaaca ctaagtccat tcaaaacaag cggtattcga
    54361 atcggcacgc cagcaatcac tactcgcggg ttcaaagaag aagatgctgt aaaagtggct
    54421 gaactagttg tcaaagcatt acaagcaaaa gatgataacg ctcaactaga cgaagtcaaa
    54481 acaggtgtac gcgaattaac tgaaaaattt ccgttgcata aaaaataaaa atttaaattc
    54541 cattagtaaa cagaaaagtt caatgttggg cttttctgtt tattttttgg gaaaacggat
    54601 tctttgacaa tatcggtgat gctctctagt atatgaggtg taattttagt cttcacacta
    54661 aatctcaggg aggaaaagtc atgactgatc gtatctcgtt agaaaaggaa gcagtagcat
    54721 tcagtgatgc aaatgcgcct catccgcgta tctatgaact agcaccggaa gaaggaagag
    54781 ttttactaga agaagtacaa gaatcacctg tgaacaaata ttccgtcgat attgaagact
    54841 tgatggtgga tactggcgaa tggggaaaac tcaatattcg tctcgtacga ccagaaggga
    54901 atatggataa attaccagtt attttttata ttcatggagc aggctgggtt tttggcagtg
    54961 ctcaaaccca tgataaattg atcagagaac ttgcggttcg tacgaattcc gtcgttgtct
    55021 ttccagaata tagtcgatca ccagaagcaa aatatccaac agcaattgaa caaaattatg
    55081 ctgtgttgca acagctgaat aaattagcca agtcaaaaaa tctggatctc gagaatctaa
    55141 tcgttgcagg agattcagta ggtggtaaca tggctacagt catgacgatc ttaacaaaag
    55201 aacgaaaggg cctcccaata tccaagcaat tgctgtatta tccagtcaca aacgctgatt
    55261 ttgatacaga ttcctatcat gaattcggag aaaactattt tttgacaaga gaaggaatga
    55321 tgtggttttg ggaccaatat acgacgaatg aagaagagcg tgctgaaatc acagcttcgc
    55381 ctttgagagc aaatataaat gaactaaatg atcttccttc agcaatgatt ttaacgggag
    55441 aagcggatgt attaagagat gaaggtgagg cttatgcgcg caaacttcgt gatgcagggg
    55501 ttcctgttac acaagtacgc ttccaaggaa tcatccatga ttttgtcatg gtaaatgcta
    55561 tggatcagac aaaggcaacg cgtgcagcaa tggcattatc tacttcttgg atcaagaaaa
    55621 aagaataagc tttgcttgtc cgcaggaaaa cttcttttca aaaacggatt ttcttaggaa
    55681 aaatggcgag tttgactagt caatcacttg attttgtttt acaattaaaa agaaacgaca
    55741 gaacaaagga gagcttaaaa aatgggcaaa tttcaagtga tcgatcatcc attgattcaa
    55801 cacaaactaa ctattattcg ggacaaaaac tgcggaacaa aggtttttcg tgaagtagtc
    55861 gatgaaatcg ctatgttgat ggcatatgaa gtatcacggg atatgccatt ggaagacatc
    55921 gtgatcgaaa caccgatcac tgaaacaaca caaaaaacgt tgtctggtaa aaaagtagcg
    55981 attattccaa tcttgcgcgc aggtattgga atggttgacg gtatcttgga attgattcca
    56041 gctgctaaag tgggacatat cggtctttat cgagatgaag aaacattgga accacatgaa
    56101 tatttcgtca aacttccaga agacattgat gcacgtcagt tgtttgtagt agatccaatg
    56161 ttggcaacag gcggatcagc aatcatggca atcgatgcat tgaaagaacg tggcgcgtcg
    56221 aacattaaat ttgtttgttt ggtagcagca cctgagggag taaaagcttt gcaagaagcg
    56281 catcctgata ttgacatcta tacagcttct ctagatgaaa aattgaatga acatggttat
    56341 atcgttcctg gactagggga tgcgggtgac cgtttgtttg gtacaaaata agtaaatacg
    56401 aaaaagggtg tgacacaact tttgtcacat ccttttttgg tcatttttaa cgtttgatgc
    56461 agaacagctt tttcacagct ttcgtttgca tataaaaaaa ccatcccaaa aatgcagaga
    56521 tggtcaaatt caaatctttt ttagttcttt gtagttaacg attactacac ccttactttg
    56581 cgtcatcaag ttcgcatttt ctgcagtttc atcaatctca acaacagcgg aatttttcaa
    56641 ttgctttgaa atcgttccag tttgcgactt gccgtgaatt gtgaacatta cgtgagtatt
    56701 gatcttgaat ttttcaccaa tttccgatgg tacgatagtt gtatcaaatt ttccaaaagt
    56761 tgccattttc ataaaacctg cctttcacat caattatacc acgttttatg aaaaatatca
    56821 tgaaattaaa ctaattttcc atcggactct ttacaatcag ccaaatagag tatataattt
    56881 cttttggata aggccagctt agctcagttg gtagagcaac gcactcgtaa cgcgtaggtc
    56941 gtaggttcga tccctatagc tggcattaaa agagaagaca gatatatcaa ggatttttaa
    57001 tccattgata catctgtctt tttgtttaaa ggaaataaag tatgctttct tagcaataga
    57061 gcatgtatta tttctataaa aatttaggag aataaaacga ctagcaatat agctgtgaaa
    57121 tcaaatatca catgaactgc ccaacttgta atgatcgagt tgcttttaat ggcagcttgg
    57181 ttgaataaca atcttgccac cccttgtatc aaaaggatgt gtgctacagt gtgtaaaata
    57241 tttccattat cataagtact gtaatggata aatccaaaga tgattgctga caagaaacta
    57301 gcgacaggaa tgctgaactt actagaaaaa atagcgagaa aatacactga gaacaattct
    57361 tctccaagta tcatgatagg caaaataata aataataacg ggctgaaagc ctcatttatt
    57421 ggattgcctg ttaaacccca tttcaaaatt tgttgcaaaa ataccgagac tgcggcactg
    57481 attactacat tgataaaaaa atatttggct atatttttga caggagcgac aggtttcgag
    57541 aacatttttt tcgtatcttt tttaccaaaa acaagtgtaa atgctataaa tccagtgata
    57601 gttaaagaaa aaatgctaat aatggatggc gcaaatagca accctaacaa accgagtaca
    57661 acgacaatag tgcccaatat ccctttttta agttctattt tttttcctaa aatgttattc
    57721 atgataataa ctcctactat tcagtttttg aagatagagt cagtatacat gaagagttaa
    57781 aataggcaat g
//
LOCUS       DADVXE010000012        56100 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.012, whole genome shotgun sequence.
ACCESSION   DADVXE010000012 DADVXE010000000
VERSION     DADVXE010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 56100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.012"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            129..647
                     /locus_tag="KB913_000772"
     CDS             129..647
                     /locus_tag="KB913_000772"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6819156.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            775..1458
                     /locus_tag="KB913_000773"
     CDS             775..1458
                     /locus_tag="KB913_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBB6819157.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1767..1840
                     /locus_tag="KB913_000774"
     tRNA            1767..1840
                     /locus_tag="KB913_000774"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1801..1803,aa:Arg,seq:tct)
     gene            1999..2358
                     /locus_tag="KB913_000775"
     CDS             1999..2358
                     /locus_tag="KB913_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBB6819158.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2481..4112
                     /locus_tag="KB913_000776"
     CDS             2481..4112
                     /locus_tag="KB913_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBB6819159.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQFPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4174..4815)
                     /locus_tag="KB913_000777"
     CDS             complement(4174..4815)
                     /locus_tag="KB913_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBB6819160.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5001..5077
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5097..5405
                     /gene="rplU"
                     /locus_tag="KB913_000778"
     CDS             5097..5405
                     /gene="rplU"
                     /locus_tag="KB913_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBB6819161.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5432..5776
                     /locus_tag="KB913_000779"
     CDS             5432..5776
                     /locus_tag="KB913_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBB6819162.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5789..6082
                     /gene="rpmA"
                     /locus_tag="KB913_000780"
     CDS             5789..6082
                     /gene="rpmA"
                     /locus_tag="KB913_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBB6819163.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6516..9323
                     /locus_tag="KB913_000781"
     CDS             6516..9323
                     /locus_tag="KB913_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6819164.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9514..10005
                     /locus_tag="KB913_000782"
     CDS             9514..10005
                     /locus_tag="KB913_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6819165.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10108..11097
                     /gene="manX"
                     /locus_tag="KB913_000783"
     CDS             10108..11097
                     /gene="manX"
                     /locus_tag="KB913_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBB6819166.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11130..11933
                     /locus_tag="KB913_000784"
     CDS             11130..11933
                     /locus_tag="KB913_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBB6819167.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11954..12868
                     /locus_tag="KB913_000785"
     CDS             11954..12868
                     /locus_tag="KB913_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBB6819168.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12951..13325
                     /locus_tag="KB913_000786"
     CDS             12951..13325
                     /locus_tag="KB913_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBB6819169.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13464..13709
                     /locus_tag="KB913_000787"
     CDS             13464..13709
                     /locus_tag="KB913_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6819170.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13881..14945
                     /locus_tag="KB913_000788"
     CDS             13881..14945
                     /locus_tag="KB913_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBB6819171.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15191..15616
                     /locus_tag="KB913_000789"
     CDS             15191..15616
                     /locus_tag="KB913_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6819172.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15609..16058
                     /gene="nusB"
                     /locus_tag="KB913_000790"
     CDS             15609..16058
                     /gene="nusB"
                     /locus_tag="KB913_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBB6819173.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16155..17009
                     /locus_tag="KB913_000791"
     CDS             16155..17009
                     /locus_tag="KB913_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBB6819174.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            17010..18347
                     /locus_tag="KB913_000792"
     CDS             17010..18347
                     /locus_tag="KB913_000792"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBB6819175.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18352..18576
                     /locus_tag="KB913_000793"
     CDS             18352..18576
                     /locus_tag="KB913_000793"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBB6819176.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18578..19468
                     /locus_tag="KB913_000794"
     CDS             18578..19468
                     /locus_tag="KB913_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBB6819177.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19477..20295
                     /locus_tag="KB913_000795"
     CDS             19477..20295
                     /locus_tag="KB913_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBB6819178.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20402..20851
                     /locus_tag="KB913_000796"
     CDS             20402..20851
                     /locus_tag="KB913_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBB6819179.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20869..22551
                     /gene="recN"
                     /locus_tag="KB913_000797"
     CDS             20869..22551
                     /gene="recN"
                     /locus_tag="KB913_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBB6819180.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22606..22722)
                     /locus_tag="KB913_000798"
     CDS             complement(22606..22722)
                     /locus_tag="KB913_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBB6819181.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22795..23751)
                     /locus_tag="KB913_000799"
     CDS             complement(22795..23751)
                     /locus_tag="KB913_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6819182.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23922..24290
                     /locus_tag="KB913_000800"
     CDS             23922..24290
                     /locus_tag="KB913_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBB6819183.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24460..24891
                     /gene="mraZ"
                     /locus_tag="KB913_000801"
     CDS             24460..24891
                     /gene="mraZ"
                     /locus_tag="KB913_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBB6819184.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24912..25871
                     /gene="rsmH"
                     /locus_tag="KB913_000802"
     CDS             24912..25871
                     /gene="rsmH"
                     /locus_tag="KB913_000802"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBB6819185.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25876..26277
                     /gene="ftsL"
                     /locus_tag="KB913_000803"
     CDS             25876..26277
                     /gene="ftsL"
                     /locus_tag="KB913_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBB6819186.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26278..28470
                     /locus_tag="KB913_000804"
     CDS             26278..28470
                     /locus_tag="KB913_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBB6819187.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28496..29458
                     /locus_tag="KB913_000805"
     CDS             28496..29458
                     /locus_tag="KB913_000805"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBB6819188.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29472..30833
                     /locus_tag="KB913_000806"
     CDS             29472..30833
                     /locus_tag="KB913_000806"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBB6819189.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30859..31947
                     /gene="murG"
                     /locus_tag="KB913_000807"
     CDS             30859..31947
                     /gene="murG"
                     /locus_tag="KB913_000807"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBB6819190.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31962..33182
                     /locus_tag="KB913_000808"
     CDS             31962..33182
                     /locus_tag="KB913_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBB6819191.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33338..34663
                     /gene="ftsA"
                     /locus_tag="KB913_000809"
     CDS             33338..34663
                     /gene="ftsA"
                     /locus_tag="KB913_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBB6819192.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34686..35927
                     /gene="ftsZ"
                     /locus_tag="KB913_000810"
     CDS             34686..35927
                     /gene="ftsZ"
                     /locus_tag="KB913_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBB6819193.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35944..36621
                     /locus_tag="KB913_000811"
     CDS             35944..36621
                     /locus_tag="KB913_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBB6819194.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36635..37234
                     /locus_tag="KB913_000812"
     CDS             36635..37234
                     /locus_tag="KB913_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBB6819195.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37249..37536
                     /locus_tag="KB913_000813"
     CDS             37249..37536
                     /locus_tag="KB913_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBB6819196.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37585..38367
                     /locus_tag="KB913_000814"
     CDS             37585..38367
                     /locus_tag="KB913_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBB6819197.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38388..39095
                     /locus_tag="KB913_000815"
     CDS             38388..39095
                     /locus_tag="KB913_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBB6819198.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39357..42155
                     /gene="ileS"
                     /locus_tag="KB913_000816"
     CDS             39357..42155
                     /gene="ileS"
                     /locus_tag="KB913_000816"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBB6819199.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42204..43730)
                     /locus_tag="KB913_000817"
     CDS             complement(42204..43730)
                     /locus_tag="KB913_000817"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBB6819200.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43745..44392)
                     /locus_tag="KB913_000818"
     CDS             complement(43745..44392)
                     /locus_tag="KB913_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBB6819201.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44576..44905)
                     /locus_tag="KB913_000819"
     CDS             complement(44576..44905)
                     /locus_tag="KB913_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBB6819202.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45082..45810
                     /gene="sfsA"
                     /locus_tag="KB913_000820"
     CDS             45082..45810
                     /gene="sfsA"
                     /locus_tag="KB913_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBB6819203.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45826..46839
                     /locus_tag="KB913_000821"
     CDS             45826..46839
                     /locus_tag="KB913_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6819204.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46839..48116
                     /locus_tag="KB913_000822"
     CDS             46839..48116
                     /locus_tag="KB913_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6819205.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48179..50881
                     /locus_tag="KB913_000823"
     CDS             48179..50881
                     /locus_tag="KB913_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6819206.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            51033..51350
                     /locus_tag="KB913_000824"
     CDS             51033..51350
                     /locus_tag="KB913_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6819207.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51380..51700
                     /locus_tag="KB913_000825"
     CDS             51380..51700
                     /locus_tag="KB913_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6819208.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51808..53268
                     /locus_tag="KB913_000826"
     CDS             51808..53268
                     /locus_tag="KB913_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6819209.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53336..53557
                     /locus_tag="KB913_000827"
     CDS             53336..53557
                     /locus_tag="KB913_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819210.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53588..53770
                     /locus_tag="KB913_000828"
     CDS             53588..53770
                     /locus_tag="KB913_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBB6819211.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53770..54183
                     /locus_tag="KB913_000829"
     CDS             53770..54183
                     /locus_tag="KB913_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBB6819212.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54306..55487
                     /locus_tag="KB913_000830"
     CDS             54306..55487
                     /locus_tag="KB913_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6819213.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55558..55722)
                     /locus_tag="KB913_000831"
     CDS             complement(55558..55722)
                     /locus_tag="KB913_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819214.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            55876..55949
                     /locus_tag="KB913_000832"
     tRNA            55876..55949
                     /locus_tag="KB913_000832"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55910..55912,aa:Arg,seq:cct)
BASE COUNT        18550 a         9468 c        12088 g        15994 t
ORIGIN      
        1 taaagatgag gaaatagaat tagaaacata taattattaa agggaaacat ttttacagct
       61 ataatttgaa aaaatttatc gttattatat gattaagaag gattgaataa agaaagaagt
      121 tgaaaacgat acctgattac aaaaaaataa cttttataag ttctataacg ttgattatat
      181 ttttaattct tattcttctc gtcgtcttgg ttccccgaat ttttggtttg actccttata
      241 ttattgagga caaagaaatg agtccatatt atgcacaagg aaatctgata tatgtacgac
      301 cgaaaaatac aaatgagatt ttagtcggag atattattac atattatgaa aattcaggaa
      361 aaaaaatctc gacgcgtcgc gtaatagccg ttgaaaacaa ccacgaagat ttttatacaa
      421 aagctgatac aaagacttat attgagcctg gagtagtaaa aaagagaaat attatcggta
      481 gtcccatctt tcagattcca tatattggac tagtcctttc aaaaacggca tttgcatgga
      541 ttcaggggtt attctttacg attgcttttt gcctaacagg aatcacagca tggaatacct
      601 ttgtagagtt gaaaaagaag cggagacgaa cacagaaatt tttgtaagaa tgttaaaaac
      661 ataaatgtat tccagagatc caacgactct tctgaacatg aaacacgaga aaacactcat
      721 gcagcttgta gatttagtca gttgttcgta taatgtgtga agaggaggag tagtatgcgc
      781 aatgaaatga tgcatcgtcc tgtagtcaaa gaagaactat tggattttat gcgtacccag
      841 caaaaaaaat taccgggtga gctaggcaaa ctggaagaag aagctcatgt agcagaagta
      901 ccagttattc cccatgaaac agttgtattt ttgaaatttt tacttggaca gcttcagcct
      961 gaacgaatct tggagatcgg agcagctatc ggtttttcat caagtgtcat ggccacgaca
     1021 atcggagaaa acgctcatgt tacgacaatt gatcgtttcg atgtcatgat cgagaaagct
     1081 aaaaaaaact atgaacgtct aggactgaca gataaagtga ctttgcttga aggtcaagca
     1141 gcagatatct tgccggagtt gtctggtccg tatgacttta tttttatgga tagtgcaaaa
     1201 tcaaaatata ttgaattttt acctgaatgc ttacgtttgt taagaaaagg tggcgttttg
     1261 atggtagatg acatcttcca aggaggaacg atcttgctcc cagatgaaga gattccccgt
     1321 ggcaaacgag ctatccatcg taaattaaat gaatttcttc gtgttgtgat ggatcatccc
     1381 gatttgacat cgacaatctt gccattaggt gatggtgtga tcttaatgac aaaggaatca
     1441 gaaacaatcg agttgtgata catgattatg gcagcctgta gataatcgat tgaatcgagg
     1501 gctcaattcg aacttgatgt aaaagtttct atatttgtaa gtcaattaaa ggatacagga
     1561 aatctaaata aacaggagta gcatgaagtc aatgtagctc ctgttttcaa ttgataacct
     1621 tagaacagct gaaggagaat gtctcgtttt aaaagattga tttagtagtt gggccaaaat
     1681 aattcattat ttgctaatta aataactatt tcgtattgac agaagcaatt taattatcta
     1741 taattattga tgttccgctg attcttgtca tagtagctca gctggataga gcatccgcct
     1801 tctaagcgga cggtcggggg ttcgaatccc tcctgtgacg ctaaaaaacc gttagaaact
     1861 gaggtttcta acggtttttc tttgtttttt gtgccaatat tgtttgtttt caaaggcaaa
     1921 taaaataaaa aaacatcctt atcgagtaca attataagga gcaaaaaaat aaaactcatc
     1981 agaaaagagg aagaagatat gacgatacta tctagaattt tagtgactct agttgcaatt
     2041 gaattttttt atatcatgta tatcgaaacg gtgagaactg attctgacac gacaagtagg
     2101 gtttttaaaa tgagtaaaga agagttaagc agaaaatctg ttcaaacatt gtttaagaac
     2161 caaggagtgt acaatggact attaggagtg ggactacttt atggagctta tctttcttcc
     2221 gcatctaaag aaatcacaag tatgctatta atatctattt tttttgttgc attatatggc
     2281 agtttgacta gcgatcgttg gattttactc aaacaaggtg ggctagctct gttggcattg
     2341 ctttctattt tcttataaat atagaaaaaa taagaattta tctaacagga aactttgtga
     2401 aaaatattac tttatctcat gaaatatgat attctaatga atggtatttt agaaaatttc
     2461 atgaaaaagg agttagatag gtgttcaaaa attatgtttc ctcactaaaa aaagaatttt
     2521 caggttatga tctttcaaga tttcagaaag atcttttggc tgggatcaca gtagctgctg
     2581 tagcattgcc tttagccttg gcttttgggg tatcaagcgg agctgatgcg gccgcaggtt
     2641 tgattacggc tatcattgcc ggtatcgtta ttggcggttt atcaggcggt ttttatcaaa
     2701 tatcaggtcc gacaggtgcg atggcagcta tcttgatgtc tattgcggca acaaagggaa
     2761 tgcaaggtgt attgcttgct acttttttag cgggtctatt tttacttgca gcaggacttt
     2821 tccgattagg aacactgact tcttttatcc cagcacccgt aattacgggg tttacttcag
     2881 gtattgctat cattattgca ttaggtcaga tcgataattt atttggtgtt cactcggaag
     2941 gtacaaacgt tattgaaaaa ctaagtagtt atcaaacgat aggatttccg ataaacacag
     3001 cctctttgat catgggaggg ctagtcattt tagggatgtt tatctatcca aaaaaatggg
     3061 cgaaacgaat gcctagttcg ctgctggcta tcattttggc aacagcagtt atgctattgt
     3121 tccatttacc agtagcaact gtgggtaaga ttccacaaac attgatcagt agtaatcgtt
     3181 tgaatatggg agattttagc ttttctgcct tgcaacaagt ggcagttcca gctattagca
     3241 ttgctttatt aggaatgatt gaaagcttgc tatgtggtgc ttcggctggc cgaatggcaa
     3301 ataagccctt agatagcaat caagaattaa tggcgcaagg aattggaaat ctgttgcttc
     3361 ctttctttgg cgggattcct gctactgcgg ccatcgcccg tacaagcgtg gccatcaaat
     3421 ctggtgcaca aactagatta gctggtatga tacatgcagt tgtcttactg ctctccatgc
     3481 ttgtttttgc gccagtgatg tcacagtttc caatgccagc acttgcaggt gttttgattg
     3541 tgacggcttg gcgtatgaat gaatgggaaa cgatcaagga gctatttact aataaatatt
     3601 ggtcagcagt tctattgttt atccttacga tgatttgtac agttatcttt gatttaagta
     3661 ttgctatcgt gatcggggtg atcggcggct gtgtattttt tgttgtcaaa agcgctgcta
     3721 tcacgatttc attagaaacg atcgattggc aaagaatggg gctgccagaa acggaaaagc
     3781 tgaataactg gacagtagtg tatattagtg gtccactgtt ttttatgtct tcagaaaaac
     3841 tcaaaaataa attggaagaa ctaaatcatc acgatggtgt cattttctcc atgcgaggcg
     3901 taccaagtat tgatttgacg gcacgtgcag tttttgatga atttcaagaa aaagcagagc
     3961 aaagaggaca aacgattatc tatacttcct tgcagccaga agtagaaaaa caactttctc
     4021 acttgtggga acatacattc acgcatcaac atcaaacagt tgctcatgcg ttgacagctt
     4081 tacatgcgaa atatactgca attagccatt aaaacaatga aaaagaacag acaagactgt
     4141 aaactgaaga ttttatggtc ttgtctgttc tttttaatat tgctgtaaaa gtgaagctag
     4201 tacttgccag tcttgatgga taacaggtac aagggagcga ttgtagaaaa tagctgctgg
     4261 atgaaaaagt ggaagaattc gatagttttt ttctgaccat tcgtaggcat ccttttgttc
     4321 tgttaattgt aagacaggcc ctgtatagag ttgaccatga tttttggtaa ccgtatattc
     4381 tttgccaagt aaacgttgaa gaccaatgtt tccaagtgtc gcaattaatt ttggctggac
     4441 cttcatcagt tcgtaatcca atattggtgc atgcgcaaat acttcggaac gagtaggtgt
     4501 ccgatttgga taaacagttt ctgactgttg tgtccgttta ttgatccgat gagtcacgcg
     4561 atacgggcgg ctccttacag cactggtgat atacacctct tctcgtgtta agccagttga
     4621 agaaagtgcc tgcatcaatt cttttccagc ttgaccgcta aaaggaacat gcgtatcaat
     4681 ctctgttttc cctggggctt ctcccacgag catcagttta ggatgaagag gtccttgccc
     4741 agcgataaat ccttctacag gacggccgtt cattcttaaa gaagcttctt gtatcagttc
     4801 ttttgggtat tccatttatg ctcctccttt ttcttttatt ataagaataa aagaaacaca
     4861 atgcgactat tttatttggt agaactgtga ggatagaaaa gcagaagtat tgcttgaatt
     4921 tttgttttac tttttgattt taaatttagt tgactaacgg ttgctgttct ggtaagctag
     4981 tactgttgta attgtggact ccacagctac aaccgctcag aacaagtaat aagcacagca
     5041 tatgctgtca cttcggatgg cgagtctaag tatatcagaa ggaggtgctt tatagcatgt
     5101 acgcaattat taaaactggt ggtaaacaag taaaagttga agtgggacaa gcaatctatg
     5161 ttgaaaaact tgacgttgaa gcaggagaaa aagttgtttt tgacgaagtt atcttagtag
     5221 gcggagaatc tacaaaagta ggcgctccaa ctgttgcagg tgcaactgtt gaaggtactg
     5281 ttgaaaaaca cggcaaacaa aagaaagtcg ttactttcaa atacaaacct aaaaaacatt
     5341 cacaccgtaa acaaggtcat cgtcaaccat atacaaaagt ggttatcgac gcgatcaacg
     5401 cttaatagcg tttgagaaag aaggcctata tatgatcaaa ggaacattta agcgaaatga
     5461 cgcaggtcag atcgtttcat tcactttgac cgggcatgct gatgctggtc cttatggaag
     5521 tgatatcgtt tgtgcgggtg tttctgcgtt agcgatcagc actgtcaacg ggattgcctc
     5581 attagccggt tttgagccga ttgttgaaat gaatgaagaa gaaggcggtt atctttatac
     5641 cgaagtcact tcaggaatga cacaagaaca aaacaatatt gctgagattc tattagaaaa
     5701 tcttttatta ggattacaat cgatagaagc tgaaaactca gaatatatcc aaattaaaac
     5761 aattaatgat aaataggagg tgcagaccat gttgttatct atgaatctac aattatttgc
     5821 ccacaaaaaa ggtggcggtt ctacatctaa cggccgtgac tcagaatcaa aacgtctagg
     5881 tgctaaacgt gctgatggac aaacagttac aggtggatca attctttacc gtcaacgcgg
     5941 tacaaaaatc tatccaggtg taaacgtggg tatcggtgga gacgacactt tatttgcaaa
     6001 agttgatggc gtagtacgtt tcgaacgtaa aggccgtaac aaaaaacaag tgtctgttta
     6061 tccagtagct caagaagctt aattgaatct tatgattaaa gaggttgtga caagactttt
     6121 gtcacagcct tttttgttta taaaaataaa agttgtagtg gaggctacga agtttacttt
     6181 gtctttttac acttaatatt tttttgccaa tttggaatca ggatgttttg ataactatcg
     6241 ttttcaattg atggaagcta tattgtttgc tatcagtgaa ataattatat ggtaaacagt
     6301 gttctttttc ttgtttccat tataaaaatc gtatcgggat ttttcgttct tttaaattga
     6361 acatttctat ctatccgcgt gttatcaaca aaacaaaatc aggtaaatag ttgacgaaac
     6421 agaaataaat acatagtatt atgttttgaa gcctaagtac aatagtctat agaaaaggag
     6481 cgataccatt ggcaaaacgc attgaccgaa tttatatgta tgtcaaagaa aaaaccgctc
     6541 atttaacaaa ggcagaatat gatcaaggag taacaacaca ggaaattgct gaagtgttag
     6601 ggattcagcg aacaaatagc agtaaagatc tgaatcagct agtgcgcgaa ggaaaactga
     6661 taaagacaga cggacgacca gtacgttaca tatatcaaac actcgttacg cacgtaaagc
     6721 cagttacaaa acatgtagtc agttacaaag aaacgccggt ctctgaagaa aaaaatacac
     6781 tccaaataga tactaaggat atctttgcaa aaatcattgg agctaacggc agcatgaaaa
     6841 attcagtgga acaggcaaaa gctgcgattt tgtatccgcc aagaggatta aattgtttga
     6901 ttacaggacc taccggatca ggaaagactt attttgcaca cgcgatgtat cattttgcaa
     6961 aagcgcatca tgtaatagat gaggaaacgg aactgattgt tttcaattgt gctgattatg
     7021 ccaataaccc tgagcttttg atgagtcatt tatttgggta cgcaaaaggt gcttttacag
     7081 gcgcagatga agaaaaaatg gggattatcg atcaagcgga tggcggtatg ctgtttttgg
     7141 atgagattca ccggttgccg cctgaaggtc aagaaatgat cttttacttt atggatcatg
     7201 gaacttacag tcgtcttggg gaaacaacga aatcccatga agcaaatgta cggatcgtag
     7261 gtgcgaccac agaagaccca ggttcttctc tattagaaac ttttgttcgg cgtatcccaa
     7321 tcaatatcaa acttccggct tttgaaaaac gtcctgcaaa tgagaaagtc gatttagtaa
     7381 aaatcatgat tgcccacgaa gcaaaccgca cgcagcgaaa gatttctttg acagaagatg
     7441 tagcaaaagc attgatcggc agtgtgacct atggaaatat aggacaattg aagtcaaata
     7501 tccagttagt atgtgcacga ggatttctaa atcatatgca atcacccgaa atctcgatca
     7561 caatcgatga tttgacagaa gggattcgta gcggattgat tcaattagca agcaaccgca
     7621 gtgcaatggc agagctttct aaaatattgg agccaaagat aactgtagca ccaaatgata
     7681 cgatcatgaa aatccaatcg gactcctatg agttacctta taatctatat gatatcatcg
     7741 gagataaagc agctttactg aagtcggatg gtttggatca agaagcaatc aatcatttca
     7801 tttctacaga tatcaacatc catctgaagt ctttctataa agaccatggt ttttctttta
     7861 atgcagacag caaattagca gaatttgtag atccgaaaat catagaagtg accaatcaga
     7921 tttatgtaat ggtcaaaaga tctttaccat atgagtttca gcaaaacttt atttatgcta
     7981 tgagcttgca tatcagttct tttttgaaaa aaatcaactt aggagaagaa cggcatacga
     8041 atgataacat ccgtgagatg gcttttgatt ttccagatga atatgctgtt gcgaaagaag
     8101 tgcgtagtta tatcgaaacg tattttcaag tggagattcc agaaagtgaa gactattact
     8161 tgaccgttct actcgtctcg ttacgggcaa atcaagcaag cggcagaatc ggtgtagtcg
     8221 ttgcagctca cggaaacagc acagcaagca gtatggtcca agttgtccaa cagttgttag
     8281 atgcagagaa cgtacgagca gtagacatgc ctttggatat ggatccgaaa acagcattgg
     8341 accgaattga acgcaatgta caagaagtag atgaaggaag cggggtcata ctcttagtag
     8401 atatggggtc ccttgcgtcg tttaattcgc aaattcaaag agacactgga attccagtac
     8461 gtactgttga tatggtaaca acttctctag ttttggaaac tgtacgaaag gtctcagtat
     8521 tagggacaga tctagatatg ttgcatgaat cattgaaaaa ttttcgaggt tacgcagaaa
     8581 tatcttctgt agaatctgtt caggaagcaa aacctattca taagaaaaaa gctgttttgg
     8641 ctatctgcgc atctggcgaa ggtacagcac aaagaatcaa agaattgatc gaacgagcgg
     8701 taaacaagcg tcaagaaaca gaattagaag ttctagcttt gtcgattgtg gaagtgaaag
     8761 aagaactgcc agttatccaa aaagaatatc agatcatagc tactactggg attactgatt
     8821 tgaatatcca agccccattt attcctttag aacgttttat tgatcaaaat atcgaagtca
     8881 ttttggatca gttgctgatg gaatcagaat tggaggaaac tgaattcatc tccctagatg
     8941 aagagtcagc taaaaatacg tgtgttgagt ttatctctga taacttcatc tttattaatg
     9001 gtagtaagtt aatcgatcca atgtggcaat tttctacaca aatctctcag acgacgggaa
     9061 tcggcgatga agaatatgga ttcaaaatca acctagtgat gcacacagca ggaatgatcg
     9121 aacgtattat tcggaatgaa ccattgactg tggaagaaaa cgaattgaca aatacaacga
     9181 atgatcctct ttatagccaa ttggcagcct cagttgttct gttggaagat cagataaaag
     9241 taaaagtgcc gatagaagaa atgtattatc tgctacgtct agtccataat cagttagata
     9301 aaaaagaata cactgtgcca tgaatacaca aaaacgatac acttttatag tgtatcgttt
     9361 ttgtgtattg gttaagaatc ctttaaattc aattagtgta tcgtaaaaaa gttggcacgc
     9421 tttttgctta tagtagtgtg tgctaggagg tggttgttca cacagaaatg ataggggttt
     9481 ctgtgaagta gtgaggaaga aggagttttg cagatggata ttcgattggc acgtatagat
     9541 gatcgtttaa tccacgggca agtcgcaaca gtttggtcga agcaaacagg tgttgaacgt
     9601 atcattgtga tcagcgatgt agtcgctcaa gataaattga gaaagtttct actaaaagaa
     9661 gctgcaccgc cggggatcac agcaaatgta ataaccgtgc agaaaatgat tcaaatctat
     9721 catagtggat tattatcacg agcaaaagtg atgcttttat tcaccaatcc ccaagatgtt
     9781 gaagcggttg tccgctgcgg tgtacagttg aagtcgttga atatcggcgg tatgagtttt
     9841 actgaaggca aatcaatgat taccaatttt gtttcagtaa atcaacaaga tattgattcc
     9901 tttcgttact tgaacagtca agaagtggag ttagagattc gaaaagtacc tgctgacagg
     9961 aaaatccttt tgatggaact actagcgaaa atcaaaaagg tgtagcaaga atggttgttg
    10021 gaaaaggtca aataattctg ttgtaatggt tagcaattat taatattttt gaatttgtta
    10081 caacaaaagt aaataggagg tataaatatg gtagggatta tcctagcaag tcatggacaa
    10141 tttgctgaag gaatcttaca atccggttca atgatctttg gcgaacaaga aaacgtcaaa
    10201 gccgtgattt tgaaaccaag tgaaggtcca gatgacttga gagccaaatt ggaagaagcg
    10261 gttgcttctt ttgataatca agacgaagtg ttattcttag ttgatttatg gggcggaaca
    10321 ccgttcaatc aatcaaacac attattcgaa gagcacaaag ataaatgggc aatcgtcagc
    10381 ggtttgaatt taccaatgtt gattgaagcc tacgcatcac gcttttcaat ggaatctgct
    10441 catgaaattg cagcacacat cattgaaaca gcaaaagacg gtgtaaaagt aaaaccggaa
    10501 gaattagaac cggcagaagc accgaaagca gcagttgaag acgcacaacc taaaggagca
    10561 cttccagaag gaactgtggt cggagacgga aaaatcaaat atgtattagc acgtgttgac
    10621 tcacgtctgt tacatggaca agttgcgaca gcttggacaa aagcagtgca accaaaccgt
    10681 attatcgttg tttcagatgc agtatcaaag gatgatctgc gtaagagact aatcgaacaa
    10741 gctgctcctc caggtgtaaa agcaaatgtt attcctatta gcaaaatgat cgaagtagca
    10801 aaagaccctc gttttggaaa taccaaagca ttgcttttat ttgaaaatcc tgaagacgta
    10861 ttgacagctg ttgaaggtgg cgtagacatc aaagaattaa atgttgggtc aatggcgcat
    10921 tcggtcggta aagtcgttgt aagtaaagta ttgtctatgg gacaagaaga cgttgaagcg
    10981 tttgagaagc ttgaacaaaa aggtgtgaaa ttcgatgtac gtaaagtacc taatgattca
    11041 cgcgataaca tggatgatat tttgaaaaaa gcaaaagctg aattagcaaa agcgtaataa
    11101 ataatattaa aatttatagg aggcttatca tgtctattat ttcaataatt ttagtcgtat
    11161 tagttgcctt tctagctggt atggaaggta ttcttgatga atttcaattt catcaaccac
    11221 tagtggcatg tacattgatc ggtttagtta ccggtaacct cgaagctggt atcgtacttg
    11281 gcggtacgct tcagatgatc gctttaggtt gggcaaatat cggtgccgct gtagcaccag
    11341 atgctgcatt agcatcagta gcatcagcaa ttattttagt tttaggtgga caaggtgtta
    11401 aaggtgttcc ttctgcgatc gcgattgccg ttcctttggc tgttgcaggg ttgttcttaa
    11461 caatgatcgt acgtacaatc gctgttccaa tcgttcattt gatggatgcg gctgctgaag
    11521 aaggaaacat ccgtaaggtt gaaatgtggc acatcattgc tgtatgttta caaggggttc
    11581 gtatcgcggt cccagcagca gcgttgctat ttatcccagc acaaactgtg caatcattcc
    11641 ttgaatcaat gccagcatgg ttaacagatg gtatggctat cggtggggga atggtcgtag
    11701 ctgtaggtta cgctttggta atcaacatga tggctacaaa agaagtatgg ccattcttcg
    11761 ttattggttt cgttgtagct gcaatttctc aattaacatt gattgctcta ggtgctttag
    11821 gtgttgcatt agctcttatt tacttgaacc tttctaaaat gggtggttca tcaaataatg
    11881 gaggcggaag caactctggt gaccctttag gcgacatttt gaatgactat taatcttgaa
    11941 ggaggaaaat aaaatggcag aagaaaaaat caaattatca aaaaaagatc gtttagctgt
    12001 tgcgtggcgc tctaccttca ttcaaggttc atggaactac gaacgtatgc aaaacggtgg
    12061 ctgggcattt tctatgattc cagcaatcaa aaaattatac aaaacaaaag aagaacgttc
    12121 tgcagcatta aaacgtcact tggaattctt taatacacac ccatacattg cttctccaat
    12181 tttaggggtt acattggctc tggaagaaga acgtgcgaat ggcgcgcctg ttgatgatgt
    12241 agcgattcaa ggggttaaag taggtatgat gggtccttta gctggtgttg gtgacccagt
    12301 gttctggttt acagtacgtc caatgctagg tgcactaggt gcttcattag ctatgggagg
    12361 aaatatcctt ggaccaatca tcttcttctt aggttggaac attattcgtt gggcattcat
    12421 gtggtataca caagaatttg gctacaaagc tggttctaaa attactgatg acctttctgg
    12481 cggattgtta caagacgtaa caaaaggtgc ttcaatttta gggatgttcg tattagctgc
    12541 ccttgtacaa agatgggtat caatcaaatt cttaccagtt gtatcaactg taaaattaga
    12601 taaaggtgct tacatcgaat gggataaatt gccttcaggt ggtgaaggaa tcaagagtgc
    12661 atttgaacaa gttaataatg gcttagccct ttctcctgaa aaggtaacaa cattacaaga
    12721 caacttagac caattgattc ctggtttagc tgcattagga ttaacattgt tatgtatgtg
    12781 gttgcttaag aaaaaggttt ctccaatcgt tatcatcctt ggtttattcg tagtcggtgt
    12841 tgttggacac gtcatcggac ttttataatc cataaaaata tagctcgggc gttgtcccga
    12901 gcttttttta tatagtatac tgttcataaa caaatatctg gagggagaaa atggttcaat
    12961 caatcaatac aaaagtagac ttggtaattg atgctacttc gtttacgggt ctgacagatt
    13021 acgggcaaat catgataggt aataatggtt ttgagtttta ccatgcgcga gatagacgca
    13081 aatatatcca aattccatgg gaagaagtgg attatgtact agcatcagtc atgctaaagg
    13141 gaaaatggat tcctcgatat gccattcaaa cgaaaaaaaa tggtacatac acattttctt
    13201 ccaaagaacc taaaaaagtg cttcgtgcga tcagagaata tgtagatgaa gatagaatgg
    13261 tacaatcatt gagtttcttt gatgtagtga aacgtggtat tcgtagtatg tttaaacgca
    13321 agtaaaaaat aaagaaaact tctaagagga ggttttcttt atttttttac tttgcagaag
    13381 aaaatatgaa atagcaaaac caattatttg tcccctttaa atcccatatg ctaaaattga
    13441 ttagcaaaga aggaggttat attatgagtt ggttatggac attgattgtt ggagccgtga
    13501 tcggagcaat tgcaggtgcg atcaccagta aaggaaattc gatgggctgt gtaacgaata
    13561 tcattgctgg actagtcggt tcaagtattg gacaagcgat tttcggcgaa tggggaccaa
    13621 aagctgcagg tatggcactt attccatcta ttttaggcgc agtgattttg gtagcagttg
    13681 tctcattttt ctttggaaaa cgatcataag tttttacaaa atagtaaact aaaaggagtt
    13741 gcagcgagac tgtgactcct ttttggcttt atttatttaa aataaaaaga agttttccgg
    13801 aaatttttat ttaactgtcg tgtacgaaga aaagtttgct ataatggaaa aaagcgtgca
    13861 aagaaagagg gagtttcatt atgatgctac gtgtagaaaa attgcgcaaa aaaatgcaag
    13921 aagaaaattt ggattcattt ttggttacca gtccgtacaa tcttcgttac ttaacgaact
    13981 ttacaggtac gacaggatta gctgttatta ctttggaaaa agcatttttt attactgatt
    14041 ttcgttatac cgagcaggcg gcagcgcagg ctcaagggtt tgaaattatt aaaaatgtcg
    14101 gacctatttt tgatgaggta gcaaacttag tacgcaaaga agaactgcac tcattagctt
    14161 ttgaggaaac aacagtctca tttttagaat attcggtttt agaagaaatc atcgatgcgg
    14221 aattagtacc tgtttcacag atgatcgaag aactcagaga agtgaaagat gaagaagaaa
    14281 tcgctattat cgaaaaagca tgtcatattg cggatatggc atatgatcac atcctgaaaa
    14341 tgatccaacc gggcatgact gagattgaag tcgcaaatca actagacttt tatatgcgtt
    14401 ctcttggcgc ttcaggtgtt tcttttgata cgatcgttgc tagcggattg cgttcggcta
    14461 tgccgcatgg tgtagcaagc aaaaaaatca tcgaacaagg tgacttgatc acattggact
    14521 ttggttgcta ttacgaaggg tacgtttccg atatgacacg tacattcgct attggtgatc
    14581 ctggggaaaa attaaaagaa atttatcaaa tagtcttaga tgctcaatta gcagttattg
    14641 atgctgcaaa accaggaatg actggtgtcc aattagatgc agttgctaga gattatattt
    14701 caaaacatgg ttacggggaa gcatttggac attctacagg acatgggatc ggtttagaga
    14761 tccacgaagg accaaacgtt tcttctcgtg cagaaaagca atttgtacca ggaaatgtga
    14821 tcactgatga accagggatc tacttaccag gaatcggtgg agtacgtatt gaggatgact
    14881 tgttgatcac agaagatgga aatcgtgtgt tgactcgttc accaaaagaa ttgatcatct
    14941 tatagtttca tcaatagaag aagtaagcgt aaaaatcagt gttcacagac tttgttatag
    15001 aaaatcactc gatttaatga tacactatag aagaactttt aagctgtaag agataataaa
    15061 gttgggtgtt ttctccaatt catagcagtt tgcagctgat cggcggcagt tttcttacca
    15121 cgtgatcact atgccgcatc atagagaatt cggatgtatc tcgtgcttag gcaaagggag
    15181 gaataaataa atggcagatg aaaaaaattt gattttaaac gcaaaccaag atttaggaga
    15241 gatcgtgatc gctcctgaag tcatcgaagt aattatcggg attgcagctt ctaaagtaga
    15301 aggcgtatac ggaatgcgcg gaacttttgc cagcaatgtc actgaattat taggacgtgc
    15361 agctcacgga aaaggtgttt acttagcaaa cgaggaagat ggcttgaaag tagatcttta
    15421 ctgttatcta gaatatggtg tttcagttcc taaagtagca atggaaatgc aggaacgggt
    15481 cagccagcaa gtccttttca tgacggatat cgatttatct gaagtcaata tccatgtagt
    15541 agctgttgtt cctgaaaaat tagaacaacc aacaatcgaa gaactttttg aagacgaaga
    15601 ggaagagaat gaataaagaa ttatcaagac acgagattcg ggaaatggca ttgcaggctt
    15661 tatttccatt agacttcaat gcagacctaa caaaagaaga tgcgattttc aacgcaatcg
    15721 aattagacca ccgcgacatg atcaacgaag atgaatcaga gtttgttcct gtttatcttg
    15781 atacgctagt tggcggtgtc tgtgcaaaaa aagatgaatt ggataaagtg attgaaaaac
    15841 atttaaaaaa caattggcac atcaatcgga tctcaaaaat ggatttggtg atcttgcgta
    15901 tcgcgatttt tgaaatgact tatgtgacag atgtaccagc ggctgttgct ttaaatgaag
    15961 caatcgagtt ggcaaaaaca tttagtgatg accgttcacg taaattcgtc aacggtgttt
    16021 tatccaatgt attgaaagaa ttagaagctg gggcgtaagt cctagctttt ttctatgaat
    16081 catcataaac ctgttataaa tcgggaaaat tctatggtag aatgaaaaca caaaaaatat
    16141 ctgggagtgg ttagatggca gaattgatta acggaaaaga attagctgaa aaaatgcagg
    16201 cagagattgc tgaaaaaatc caaaaattga aagataatgg tatccatccc ggattagtcg
    16261 ttttattggt aggggaaaat ccagccagcc aaatctatgt aagaaataaa gaacgtgtag
    16321 caaaagaaat cggaatccat tcattggtag agcgttatcc tgagacgatt tctgaagacg
    16381 aactacttgc agaaattgaa aaatacaatc aagatcctag ttttcatggt atattggtcc
    16441 aattaccatt gccaaagcat atagatgaag aaaagatcct gttagctatc cgccctgaaa
    16501 aagacgtaga cggttttcat ccgatgaatt taggcagact ccttgcgggt aaaccggaca
    16561 agattccttg tactccatac ggcatcatga aaatgtttga agcttattct atcgatccgg
    16621 cgggtaaacg agcagtagtt atcggacgaa gcaatatcgt cggtaaaccg atggctcagc
    16681 tactcttgat ggcagatgca actgttactg ttgctcattc taaaaccgaa aatctggctg
    16741 aactggcaca agaagcagat attttagtcg tagcaatagg acgtggacat tttgtcacaa
    16801 aagaattcgt aaaaccaggt gctgtagtga tagatgtagg gatgaatcgt gatgctaacg
    16861 gtaagctgat cggtgatgtg aaatttgatg aagtggagcc tattgcaggc tggatcactc
    16921 ctgtgccaaa gggtgtaggg ccaatgacta tcacgatgct gatgtatcaa accgtaaaat
    16981 ctgccgaagc ttttggagca ggtgaataga tggcacaaga atatttaact gtcactacat
    17041 taacgaagta tttgaaaaga aaatttgatg ccgatcctta tttagaacgc gtatatttaa
    17101 caggcgaaat atcgaatttc cgtttacgtg ccaatgccca tcaatatttc agcttaaaag
    17161 atgaccatgc aaaaatatct gctattatgt tcaaaggagc attccaaaaa ttacgattcc
    17221 agccaaaaga aggaatgaaa gtccttgtcg ttgggcgtat ttcattatat gaagcgggag
    17281 gttcttatca aatctatgta gagcacatgg agcctgatgg aataggtgct ttatatcaag
    17341 aattggaaga acgaaaagaa aagctgatga aggaaggcct ttttcaaggg cctaaaaaaa
    17401 tgctgccacg tttcccaaag cgaatcgcgg tccttaccag tccaagcgga gcggttatcc
    17461 gcgatatcat cacgacggtg aaaagaagat atccaattgt ccaattggtt ttgttcccaa
    17521 cagttgtaca aggaaaccaa gcagcggaca atgttgtcag gaatatccag agagtagaag
    17581 agatgggcaa tttcgataca atgatcatcg gtcgtggggg tggttcgatt gaggatttat
    17641 ggccgtttaa tgaagagcgg gttgctcggg cgatttatca agctaatacg ccggtgattt
    17701 catctgtagg acatgaaaca gataccacga tcgctgattt agtagcagat gttcgggctg
    17761 ccactccaac agcagctgca gaattagctg ttcctgtttt gtcagaagag ttgatgcgca
    17821 ttcaagaacg gcaagctaga ttgcagcagg cgtttgtacg ccagatccag cgcaaacaag
    17881 aacggttcga gcgtgctcga cgttcctatg tatttcggca gcctgaaaga ttgtatgaag
    17941 gtcagaccat caaattagac cagttgaaac agcgattata tcaagctaca cagcaaattt
    18001 atcatgcgaa agaaaaacaa acgatcgcat taagccacca attggaacaa gtggctccgc
    18061 tttatcgagt taaagcagct cgccaagaaa ctgcttatct agaaaaacgc ttagaagaga
    18121 aaatccaaca atatatgaaa caacagcagc agcgttttgc tcaagctgtt caatctcttg
    18181 atttgttgag tccattgaaa atcatgggaa gaggctacag ctatacgacg ttaaatgatc
    18241 aagtagtaaa aagtgtcacc gagattcatc aaggggattt gctgacgatc cattatcaag
    18301 atggaatcgt taaaggacaa gtacaagaga tagacaaagg agaataaaaa tatggaaaat
    18361 ccaacttttg aagagtcact gcaagaatta gaaaaaattg tcatgcagtt agaacaagga
    18421 gacgttccat tagaatcagc tctagattcg tttaaacgag gaatggaatt aagcaaacat
    18481 tgccaagata cattagctaa agcagaagag accttgacga aaatgatgac agaatcaaat
    18541 gaagaagttg attttgacgg aaacgaggaa agctgagatg agattaactg acttttcagc
    18601 tattcatcta cctgctgtag aaaaagaaat cttgtctttt ttagatgagc atacaacgga
    18661 tagaggactc tatgatgcga tgagttattc agtgaaagca ggcgggaaaa gaatacgtcc
    18721 cttattactt ttaacggccg ttgcttcctt tgatgagcct attgatgttc ccgtctatca
    18781 agtagcagct gctttagaaa tggtgcatac gtattccttg atccacgatg atttgcctgc
    18841 gatggacaat gatgatcttc gtagaggaaa acctaccaat cataaagtat tcggcgaagc
    18901 attagctata ttggccggag atggtttgct tacaggagca ttccagctaa tcagtatggc
    18961 acacttaggt aattctccta agcttctgct gcttcagcaa ttagctgttt gtgcgggatc
    19021 acaaggtatg gttgctgggc aagctgcaga tatcgagggc gaatcgaaaa agctttcttt
    19081 agaagaatta gcatttattc atgaaagaaa gacagggcat ttgattcgtt atgccttgct
    19141 ggctggtggc atattagcga agcaacctga agaaatctta ttgctacttc aacgattagc
    19201 cgaacattta ggtttagctt ttcagataag agatgatcta ctcgatgtga ttggtacaac
    19261 gaaaacatta gggaaaacag ctggtaaaga tgaacgtatg gaaaaaaata cttacccgcg
    19321 tttattaggc ctagaaaaga cacgtgaggc gttggagatt gagctgttat ccgccaacaa
    19381 gatcatagac aaattagaag aggacgtttt ttcttttgat ggcgggctga tgcgccagat
    19441 gatcaagcaa tttgatgtgg agaaatgagg gaaagaatgg aaaaagaacg cgtagatgta
    19501 ttagcggtca aacaaggatt atttgaaaca agagaacaag ccaaacgttc agtgatggct
    19561 ggtttgattt acaacgaaaa aaacgagcgg tttgataaac cgggagaaaa aattccagtg
    19621 agtagtgaat taagagtcaa aggtaaaaaa cttccttatg tttctcgagg gggattaaaa
    19681 ttagaaaaag cactcaaagc atttgatcta tctgttgaag gaaaaacatt gttagatatt
    19741 ggtgcatcca ctggcggatt tactgatgca gctttgcaaa atggcgcaaa aatgagttat
    19801 gctttagacg ttggctacaa tcagctagct tggaaaataa gacaagatcc tagagtcgtc
    19861 gtaatggaaa gagtgaattt tcgttatgca aaacccgaag actttacctt aggaattcca
    19921 gaagttgctg ttatcgatgt ttcttttatt tcactaaaac tgatgctgcc tccattacat
    19981 gctattttaa aagaagaggg agaagtgatt gctttaatca aaccccaatt cgaagcaggc
    20041 agagaagctg tagggaaaaa cggaattgtt cgtgaccctc agacccatca aaaagtttta
    20101 gaagacattt tgtcatttgc ggcacaaggt ggatatgatg tgctggaatt aagttattct
    20161 ccgatcacgg ggggagaagg aaatatcgag ttcttggctc acttgaggaa agtacccgaa
    20221 agcggaacaa tcaattcagc tattaatatg gcagaagtgg tttcaaatgc acacgaacag
    20281 tttgaccata aataaattgt aactgtgaaa atcaagtgag aagtatgcgg attcttcttt
    20341 attataccaa ggaaataagc tatcattgat taagaagaat atgctaagga gcgaagacgt
    20401 aatgagaaaa aaagatcggc atcgtttgat tactcgattg ttgagtgagc aagatatccg
    20461 aaagcaggaa gaatttgttg aaatcctgaa aagcaaagga atatctgtta ctcaagctac
    20521 gatttccaga gatataaagg aactgaaact gatcaaggta ccggcttcag atggcggcta
    20581 ccgttatagc ataccagctg aaacaaacga agatgtaaat actaaattgg aaaaactatt
    20641 aaaagacgct ttcgtggcag ttgaccaaat ggaaaaattt gttattttga aaacattgcc
    20701 gggaaatgct tcggcagcag caaatttgat tgataaacgt tacaagaaag aattattttc
    20761 gattatcaat gatgacgata atgttttgat gattacacga actgaagacc aggcagtttt
    20821 attgaagaaa gacttcctgc attaccttta agttgaggag cgaatgtgat gctacaagaa
    20881 atcagtatta ctaactttgc gattattccg gaattgcggc tttcttttca cgaaggaatg
    20941 accgcgctga ccggagagac tggtgcgggt aaatccatta ttatcgatgc tttaggtctg
    21001 ttagcaggag gaagaggttc aagcgattat atacgtcaag gagcagaaaa atgtgtgctt
    21061 gaagggttgt ttgaactacc aaaacaagaa ggattctctg aactgatggt tgaattaggg
    21121 atcgaaacag atgaggacaa tctgattgtt cgacgggata tgtccttaac tggaaaaaat
    21181 gtttgtcgag tgaatggtca tattatcaca ttagctaatc tgagaagaat cggcagttat
    21241 ttagtagata tccaaggaca aaacgaacat caggaactgc tccagcctga atcacatctt
    21301 gctttattgg atcgttttgg agatgtagct ttccaacaga agaaaaagag ttatcagcaa
    21361 gaatatatct cttatcgtga gctggaaaaa agggtacgaa aagtgcagca aaatgaaaaa
    21421 tcctatgttc agagaataga tatgctccat ttccagcaag aagaaatagc tgctgctgat
    21481 ttgcaagtcg gagaagaaga gaaattaaaa gaagaaagag aaaaacttag caattatcaa
    21541 aaaattgctg atggattagc tgcaggttac ggagcactga cgaataatga acaaaacagt
    21601 gtagatggtg ttggcttggc cgtttcagaa ctgcaaggga tcgcccatct agatgtggag
    21661 tatgaagcaa tttatgaaaa tatccaaagt gcttactatt tgctgcaaga tgcaatcggc
    21721 gatatgagtc gtcagattga tttattggag ttagatgaga gtcgtttaga agaagttacg
    21781 caacgtttag aattaatccg acagttgaaa cgtaaatacg gcgaatccat tgagtcaata
    21841 ttggcttact atgacgaaat caccgaagag ctagcttctt ctgatttttc agaaggtcaa
    21901 ttggacaaaa tgaaagagga actagagcaa aaagagcttc tacttcagca acaagccgca
    21961 gatcttcatg aagcgcgtaa aaaaatcgca aaagaattgg aaaaatccat tctgcatgaa
    22021 ttgaaaagtc tgtatatgga aaacactgag tttgaggtac gtttcttaaa agaagaaaat
    22081 agacaattga atcatgatgg atttgaccaa atcgaatttt acattacgac caatccagga
    22141 gagccactga agcctttggt gaaagtcgct tctggtggcg aactgtctcg gatgttgctt
    22201 gctttgaaaa ctattttttc ttctgagcaa ggtgtgacaa gtattatttt tgatgaagtg
    22261 gatacaggtg tgagcggaag agttgcacag gccatcgcag ataaaatttc tcaaatatcg
    22321 aaatactctc aagttttgtg catcactcat ctgcctcaag ttgctgcagt cgccgactat
    22381 caatattata ttgtgaaagc agtgattgat ggacgtacgc aaacttctgt ttcagagttg
    22441 aaaacaaaag aaagagaaga agaaattgca cgtatgctgg ctggaagtga gattacaaaa
    22501 ctcacactcg aacatgcaaa agaactattg aaactcgcaa aaaggacctg agccacctcg
    22561 cagtggttca ggtccttttc agcagctgat agctatattt tatttttaca tgacactcat
    22621 tacagcagtc aatacaacag atccaatcgt taaaatcagc attgtccaaa tgacaaattt
    22681 tgttacttta gcaaaagtac ttgtttgttt tttttcacgc attgttttca acctcgtcat
    22741 taattagttg attcaagtgt acaatctttt ttccatttcc acaagagggc ttttttataa
    22801 aaacttccct ttttttaaat aataggtagt tacgatacaa ataaataatg ttaatagaac
    22861 tagccatata aaggcatcat ccctttcagc aataggtaac ttaatgttca ttccatagat
    22921 actgccgacg attgtcggta tagttaaaat aatcgttaaa gaagttaaaa ttttcataat
    22981 attattcaga ttattcgata cgattgctga aaaagtctga ttcatttgtt ctactagttt
    23041 taattgaatg cgagaagtag tcattgcctg ctctgtttcc accaatacat cacgtaaatg
    23101 atttttcaaa gcatgatttt cttggaaaag tttattttgc gctagttctt tcaatgcatc
    23161 taaattagca gaagtcgctt ctctgaaata aacgaggctt ttttggatat ccatgatttg
    23221 ataaagttgt ttgttttcag tggatacttg aagtttggct tccaaagtat cgcattgaga
    23281 ttgaagcgta gctaaataac tgttgtaaga gagtgtgacc tgccaaatga attgaaagaa
    23341 gatattgaga ttaggcgaaa tatcactttt tggaaaggtc tggctaaaga ctttctttaa
    23401 aaacagtggt tcatgattcg taattgtgat aagcttcttt ttgggcgtca aaataataga
    23461 gagcgggtat gtatccactt gaaaataacc gctaggactt gttttagcaa aaggatattg
    23521 taacaataat aacgctggct ttgtcaactt tgattgattg aattcttctg tacgggaatt
    23581 ttctgcatcg tccaatatgg aagtgatgta atctgacgga atttcaaatt gatgtgtcag
    23641 ctgatgaatc tcttcttgat taggacgttc tacacaatac cagatcgttt ggtcagtttc
    23701 ctttccggta ttacgcagtt tctcattatc taatgtaaaa tatttgatca tgattttcct
    23761 cctgttgcct gtttctttta ttataacgga tagggaattg gaatacatgg aatgtgtttg
    23821 taagatatag aatataactg cataaattta aataaaatga aacagttgtg taaagtatat
    23881 acagtatact tgaagcaacg ataaaaaagg agtttacgtt catgggcaca ttcacaccac
    23941 ttatcttgtt ttggtatatt tacccggtaa tcgttttgtt tggttgccaa tttcttgtaa
    24001 aattattttc gttaaatcgt cgttttaaaa taaaagcccc tgatttggcg attccttttt
    24061 tgtggggcgg tatgcatgca ttgtctagaa atacagggac aatttctatc ttaccgtttt
    24121 tctttatttc tgttttgcta atgggaattt gtattgctgt tttccaagca tattattatg
    24181 aagaaattat ttatccgcgt tatttcaaga tgacttggcg tttggttttt ctgttgacaa
    24241 tcgtcttgta cgctgtcttg atcattgtga acatactttc ttacctatga aaaaaataga
    24301 aaagctgtaa aaagtctttt aaaaggcttt ttgcagcttg atttttaaaa aaatgtttat
    24361 gaataaaaaa agttgttccc ggatttccca gaaaaggtgg tagaaagtgg gggattgtgg
    24421 tagactaatt ttagttagtg gaggaatggg gggctttcaa tgttgatggg tgaattccaa
    24481 cataatattg atgcaaaagg acgtttaatc gtgccctcaa aacttcgtga agaacttggc
    24541 gaaaagtttg ttctgacacg cggattggat ggctgtcttt tcggctatcc gatgagcgaa
    24601 tgggaaaatc tggaagctaa actgaacgaa atgccgttgg ctaaaaaaga cgcacgtact
    24661 tttgtgcgat tcttctattc ggctgccact gaatgcgaac ttgataaaca aggacgaatc
    24721 aatataccca gcacgttaag aaattatgca gctttgacaa aaggttgcgt agtcatcggt
    24781 gtatctaacc gaattgaaat ttgggatgag acacgatggc aagatttttc tgcagcagca
    24841 gaagagaact ttgacgaaat tgctgaaagt atgattgatt tcggactata agaataggaa
    24901 gaggctgact aatgactgaa acatttcaac actatacagt catgttgaaa gaaacggtag
    24961 atggattgaa catcaaaccg gatggcgttt atgtagactg tacactcggc ggtgccggac
    25021 atagtgaata tttattaagc caactaagtt ctaaagggca tctgtatgcg tttgaccaag
    25081 atcaaaaagc aatcgatcac gccaagctgc gtttagcttc ttatgtcgaa caaggtatgg
    25141 tcacatttat caaagcgaac ttcagagaat tagaagaacg cttgagtgag catgtagata
    25201 aggtagacgg cattttgtat gatctagggg tttcctctcc tcagctagat gaagcagaac
    25261 gtggatttag ttatcatcaa gatgcaccgt tggatatgcg catggatcag tcagctcctt
    25321 tatccgctta tcacgtaatt aatgaatatt cctaccatga attagtaaag attttcttcc
    25381 gctatggcga ggagaaattt tccaaacaaa ttgctcgtga aatcgaacga gtacgaaaaa
    25441 caaaaccaat ccaaacaact ggtgagcttg tcgaaatcat taaacaagtc atcccagctc
    25501 ccgcaagaag aaaaggcggg catcctgcaa aaagaatttt tcaagctgtg cggattgcag
    25561 taaatgacga actcggtgcc gaagaggcct ctttagaaca ggcaatccgg ttattgaaag
    25621 tcaatggaag aatcagcgta atcacattcc attcattgga agacagaatt gtcaaaagta
    25681 tgtttaaaga atatagtacg gtacaagatc taccaccggg acttcctgtc atacctgacg
    25741 aattccaacc agaactgaaa gtcattactc gtaaaccaat ccttccttca gaggaagagc
    25801 taacagaaaa caatcgatca cgcagtgcaa agttacgtat tgcagaaaaa ataagaatga
    25861 aagaggagta gaatgatggc agaattaaag aaaatgcaag attacgaata tgatttacct
    25921 gaattggtgg atcagccgga acaacaaatg cctgattctt cttcgaatca agaaatcatt
    25981 cttccacaat caccggcaaa acgattaaag cagatttctg ctttggaaaa aattgctgtg
    26041 gcaagcgtgg cgattgctat tgttgcttta tgtgttttaa cagttatgct gcgcacaaat
    26101 atcagcggag ctgaaaaaga aatcacgtca atacaaacag aaatcaatga taaaaagcaa
    26161 gaaaaaacga gtttagaaca agaaaaaaac gaactttctc gtactgaacg gattaaacaa
    26221 atcgcagaag aaaaaggatt gtctattaat gacgacaatt taaggaaagt gaagtaaatg
    26281 agtcttaaaa ataaaattcg gcggtttatg gaaaagaaaa atctaaatcc gatgaacaat
    26341 cgcaaaaaag taggtatcat tttatttgct acgagtattg gattgttctt tttatttgcc
    26401 gtccgtttct cgtatatcgt tattggaggt catgttgctg gtacctcatt agctgaaaaa
    26461 acaaaacagt tgtaccaagg aagtgaagta gtaaaagcaa aaagaggaac gatttatgat
    26521 cgtaacggtg tggcgctcgc agaagatgcc tcctcttatt caattaaagc gatactctca
    26581 aaaacatata cctctgggga taaaaaactg tatgttgaag aaaagaattt tgataaaata
    26641 gcagaaatcc tgcataagaa tctttctata gacaaaaaag atgcactgaa tattttagag
    26701 gacggcgcaa aaaaagagct gtatcaagtt gaatttggta gctatgggaa aaatatctcc
    26761 caagaaacca agcaaaacat cgaagcggac atgaaaaaag aaggtgtcgc tggtctttat
    26821 tttgtcgacc atcaggctcg gatgtatcca aatggcgtct tttcttctca ttttattgga
    26881 tacgcagttc cagacaaaga tgagaatggc ttagttggta aactaggttt ggagtctgct
    26941 tacaatgata tcttgagcgg taaagatggt aagattattt atcaaaaaga taattttcaa
    27001 aatcctctgc caggtacagt ggcagaagaa gaaaaagctg tcgacggaca agatatctac
    27061 acgactttag acagcagact acaaagttat ttagaaacac tgatggatca agtaaatgaa
    27121 gaatatcagc cagaagaatt gacagcagtc ctgatgaaag caaaaaccgg agaaatcttg
    27181 gcaatgggac aacgacctac tttcaatcct gaaacaatgg aaggattgac tggaaaagat
    27241 gctatctggc gtaatttctt ggtacaagat agttatgaac caggatcaac catgaaagtt
    27301 ttcactactg cagctgctat cgaagaagga gaattcaacg agaatgaaac cttccaatct
    27361 ggaaaaatcc aagtagaaga tgctacgatc aatgaccatg actttggtga aaaaggtgtg
    27421 ctgaccatgc gtcaagctct ttcatggtca agtaacgtcg ggatggtcat actggaacag
    27481 cgattaggcg gacgatggta taactattta caaaaactgg gatttggaca aagtactcat
    27541 tctggattag atgatgaagt aaacggtgct ttacctacat taaatattgt cgaccgagca
    27601 atgagtgctt atggacaagc ggtaggtgtg acgaatttcc aaatgatgaa agctttcact
    27661 tctattgcga ataacggtac aatgattcaa cctcgatata tcagcaaagt ggtggatccc
    27721 caaactggag aagagcgaac aactcaaaca gaagttctag ggcaaccttt ttcaaaagaa
    27781 acaacagaaa aagtccgtga atatatgaga gatgttgtcg aaagcgaaaa ctacggtagt
    27841 gcttatggtg tatatagtgt acctggatac aatgtatcgg caaaaaacgg aacagcccaa
    27901 atcgcttctg atacaggggg atatcaaaca ggagatacag cctacctgta ttcgattgtg
    27961 gagatggttc cttctgaaga tccagactat gtcttgtatc taacaatgaa acaccctaag
    28021 acatatgatc gaatggcatt ggctaaaatc gcaaatccat tgatgaaacg ggcaatggat
    28081 tttaaagaaa ctgaagaaga ttcagataca gaaacaaaaa cagaaaaagt atccgtagcc
    28141 gattatcgta atcttgaagc ggacgttgca gcagctgatg ctcaaaaaag tggactgcaa
    28201 cctgtagtga tcggtaatgg taaaaaagta caaaaacaat ctactgccaa cggtgatcag
    28261 ttgatctctg gagaaaaact gatcctatat actggtggtg ataagctgat gcctgacgta
    28321 acaggatggt caaaagcaga tatcatgaag ctggggaaaa tcctcggtat tgaagttagt
    28381 tttgatggag atggttattg tgtcaaacaa gaacttgctc catatgaaaa aatcactgaa
    28441 gacaaactta gttttacttt agaagaataa gaagagaaat aggagagaaa agagcatgga
    28501 atggacacaa gcattgattc ccattgtcag cagttgtgca atgacaattg ccgcaatgcc
    28561 gctatttatt ggttattttc aaatgaaaaa gcaaggtcag gcgattcgtg aggagggacc
    28621 aaagtggcac aatagcaaag ccggaactcc tacaatgggc ggcttagtgt ttctgatcgg
    28681 ctctattttg acaggaattt gggttggagc ttggcaaaaa cagctaactc ctactctttt
    28741 catcttgctt tttgtattag cgttatacgg agtaatcggc tttcttgatg attttataaa
    28801 aatattcaag aaaagaaaca tgggactgaa ctcgaagcag aaattgattg gacagattct
    28861 agggggaatc atcttttatc ttgtttaccg ttctgaaggt tatccaggtg tattgaattt
    28921 cttcggacta gatctacctt taggaatcat ttatggtatt ttcgctctct tctggcttgt
    28981 tggattttca aatgcagtaa atctgacaga tggcatcgat ggattagttg ctggcttagg
    29041 aagtatctct tttgcagctt acggtctaat tgcttggcat cagcatcagt atgatgtatt
    29101 aatcatttgc ttaagtgttt taggaggttt actgggtttc ttcgtctaca acagaaaacc
    29161 tgccaagatt tttatgggag atgtcggttc attagcgttg ggcggacttt tagcggcaat
    29221 ttctataatg ctaaaccaag aatggacatt gcttttgatt ggtttgatct atgttatgga
    29281 aacagcaagt gtgatgcttc aagttacttc ctttaagctt acaggaaaac gaatttttaa
    29341 aatgtctcca attcatcatc actttgaaat gtgcggatgg tcggagtgga agattgatac
    29401 agttttttgg ttgatcagca ttgtgacttc gttgatcaca ttatggatcg tttggtagga
    29461 gatgacggga aatgaaaaaa atatcaacat atgaaaataa gaaagtgctt gtcttaggac
    29521 tcgcaaaaag cggagtaagt gcggccaaat tattacatga attgggcgca cttgtcaccg
    29581 ttaatgatgg aaaacctttt gacgaaaatc cggaagcaca agagctgctt tctttaggga
    29641 taaaagtaat aacaggtagt catccaatcg aattgttgga tgaagaattt tcattgatgg
    29701 tcaaaaatcc agggattccc tacagtcatc ctttagtagc aaaagcccaa gaaatgggta
    29761 ttccggtaat tacggaagtt gagctagctt acgaagtagc ggaatgccca attattggga
    29821 ttacaggaac gaacggaaaa acaacgacaa caacgatgac aggactacta ctgaatgcag
    29881 gagcagatca aggaattgca cgtttagcgg gtaatattgg gtatccagca agtggtgtag
    29941 cgcaagaagc aaaatcagaa gataaaattg tgatggaatt gtctagcttc caactcatgg
    30001 gaatcacaga tttccgccct catatagcgg tgattaccaa tatctatgaa gcacatattg
    30061 attatcatgg tacaagaaaa gaatatgtca aagctaaatg gaaccttcaa aaaaacatga
    30121 cagaaaaaga ttatctgatc cttaactgga atcagtcaga actacaagaa ttagcgcaaa
    30181 gaacaaaagc acgcgtactg cctttctcga caaaagaagt gttggaagac ggtgtgtatg
    30241 ctgacgatta ctcaatatac tataaaaaag aaaaaataat ggaaatatct gaacttggcg
    30301 taccaggtaa gcataatgta gaaaatgcac tagctgctat ttctgtagca aaattgtatg
    30361 gtatatcaaa tgaagctata cgagaaacgt tgcatttttt ccatggcgta ccacatcgta
    30421 cgcaatatgt aggagaaatc caaggcagaa aattttataa tgattcaaaa gcaaccaata
    30481 ttttagcgac taaaatggct ctaagtggat ttgaaacgtc taaggtcgtg ttattggctg
    30541 gcggattaga cagaggaaat acatttgatg aattaattcc ttcattaaaa ggaatcaaag
    30601 caatggtcgt atttggccaa acaaaagaaa agttgatgga tgctggaaaa aaagcaggca
    30661 tcgagacaat agtaacagcc gattctgtag aacaagcagt tcctttagca ttagaaaaca
    30721 gtacagatgg tgatgtagtt ttattatcac cagcgaatgc cagctgggat caatacccaa
    30781 attttgaaac tagaggaaac agattcatgg aagctgtgaa ccgattaaaa tagaaaaagt
    30841 agaagcgagc gataaaaaat gaaaattttg gttacaggcg gaggaacagg gggacatatt
    30901 tatccagctc ttgcctttgt caattatgta aagactcaag aaccgaatgc tgaattcatg
    30961 tatgtgggag caaaacgagg tctagaaaac aaaatcgtcc ctgatacagg aatgcctttc
    31021 cataccttgg agattcaagg atttaaacga aaaatttcca tgcataacat caagacggtc
    31081 cgattgtttc ttaagagtat ccgtcaagca aaaaaaatcc tcagtgattt tcaaccagat
    31141 atcgttatcg gtactggagg atatgtttcc ggagcggtag tgtacgctgc agccaaaatg
    31201 ggtattccaa cagttatcca tgaacaaaac agtgtaccag gtgttaccaa taaattttta
    31261 agccgatatg tggatcggat cgctctttca tttaaagatg cggcttcctt ttttcctgaa
    31321 aacaaagcag ttcttgtagg taatcctcga gcacaagaag tagcagatac taaaaaatca
    31381 gatattttga aaacatttga tttggatcca gaaaagaaaa cagtcttgat ttttggcggt
    31441 agtcaaggag cacttaaaat caatcaagca gtatcagttt ttttaagtga atatattcct
    31501 tcttcttacc aagttttgta tgcttcagga gatagatatt atgaagagat cctaaataaa
    31561 ataaatcctg aaatacaaaa tattagtgtc cagccttata tcaaaaatat ggcagaggtc
    31621 atggcttcca gtgatctgct ggtggggcgt gctggtgcaa cttcgatcgc agaattcaca
    31681 gctctggggt taccggcagt gttggttccc agcccatatg ttacgaatga tcatcagact
    31741 aaaaatgcaa tgagtcttgt tcacgcagga gcagcaaaaa tgattgcaga taatgaacta
    31801 acaggtgaat cactaagtca gacagtcaac gaaatcatgg gtgatgaaga attgcaaaag
    31861 caaatgtgcc gagcttctaa agaacaagga atccctgatg cttcaaaacg tctttatgac
    31921 ttagtaaaac aaataatcaa aaaataaagg cggtggtctt agtgagtaag aaaaaagaac
    31981 caaaaaaatt gtctcatccg tcttctgatg aaaacaattt gactccttgg caaaaggcta
    32041 accgaaaata tctggcagaa caagagatga aaaaccaaga gccaaaaaaa gaagacataa
    32101 cattagatac acccctttca gattctgaag aagaaaaaac ggttcaagag gaacagcaag
    32161 aagaaagcca gtccgagaaa aaaatcgaat tttttgaaga gatcaagcaa aagaaaaacg
    32221 gtggaccata taacggttct tttttgaacc ggctgcccaa tttaaaaagt caacggcaca
    32281 aagtactatt tcgtcggtta gctttgatca tcactgtatt gggtataccg ctgatttttt
    32341 tgatctatta tgtttctcct tatagcaaat tacaagcagt tgcagtatca ggcaataaga
    32401 cagtcaacag ccaagaaatc atctctgata caaaattgtc attaggagaa aatgtttggg
    32461 gacagtattt tcatcgatct acttatatcg atcgccttaa aaaagcacag ccaagaatcg
    32521 aaacagcaaa tatacatttc aaagggatga atgaattcga tttggatgta acagaatata
    32581 aagagattgc tttgatcgca aaaaacaatc aatactaccc agtgattgaa aatggaacag
    32641 tattagatga aaaagtagca aatcctacaa aaaatctccc tatcttggaa gagttcaaag
    32701 actctgcaaa aatcaaagaa ttaacaaagc aatacaatca gttatcatca gaattacaaa
    32761 aagcaatttc tgaaatcaag tacacgccaa gagcaagcaa taaaaatctg atccaattga
    32821 atatgaatga cggcaatcaa gttattgtaa atatcaataa tcttgcgaac caaatgaaat
    32881 attattcgca agtagccaaa gatatggatg aaaaaggtgt gatcgacatg gaagttggta
    32941 tcttctcgca tccttacggt agcactcaag aaacggaaga atcgggccaa tcggaagaaa
    33001 caactgaaag tgaagaaaat gcggatcaaa caaacgaatc aagtgaagag gcagaaacgc
    33061 aaaaagcaca aacacctgga tcgtctagca caaacggatc atctgattca aatgattcaa
    33121 gtgaaacaag tcaaatagaa gataatccaa gtacaactcc gtcaagttta aatgaaaatt
    33181 gataaaacaa ctttaaaaag taagaatgta ctttctaaaa accagtaatt tatggtagaa
    33241 ttggaagcag tgaatatatc tattaataag tatattttaa aacggacgct agttgttcgc
    33301 ttgtatatgg aatagtaagt aggagggaat cccattcatg gcaaaaacag gaatgtatgt
    33361 aggccttgat attggaacga catctgttaa agttgtcgtg gctgaatata tcgacagcca
    33421 aatgaatatt attggagtag gaaacgcaaa atcagaaggg attaaccgag gcattatcgt
    33481 tgatatcgat aaaacggtcc aagcgataca acgagcagta cgacaagcag aagaaaaagc
    33541 aggtatccag atcaaaggcg taagtgtcgg tttgccagca aacatgcttg aagtagaaaa
    33601 ttgccaggga atgattgcag ttaacggaga ttcaaaggaa atcaccgatg aagatgtcag
    33661 aaatgtggct tcagctgccc ttgttcgttc aatacctcct gaacgtcaaa tcgtgtcaat
    33721 attgccacaa gattttactg tcgatgggtt cgagggaatc aaagatcctc gtggaatgat
    33781 cggcgtaaga ttagaaatgt acggtctgtt gtttacagga cctaaaacga tcatccataa
    33841 catacgtaaa tgcgtggaaa atgccggatt aatcgtcaac gaaatggtga ttactccttt
    33901 agcgctgact gaatcaattc tttctgacgg agaaaaagat tttggtacga tcgtcattga
    33961 tatgggtggc ggccaaacaa caacggctgt tatgcatgat aagcaattga agtttaccaa
    34021 tcttgaccaa gaaggtggcg aatttgtcac taaagatatc tctattgtat taaatacgtc
    34081 atttaacaat gcagaagcgt tgaaaataaa ctacggggat gcatacccag aacggacatc
    34141 accagatgaa gaatttccag tagatgtgat tggtcagtca gaaccagtga aagtcgatga
    34201 acgctacttg tcagaaatta tttcagctcg aatggaacag attttcaaca aagcaaaaga
    34261 tgcattggac caaatcgaag cattagagtt gccaggtggc gtcgtattga caggcggagc
    34321 tgctagtctt cctggtgttg tggacttggc acaagaaatc ttcggcgtaa atgtaaaatt
    34381 gtatgttcca aatcacatgg ggctgagaaa cccggtattt acaaatgtaa taagtatcgt
    34441 ggattattca gcaaacttga gtgaagtgta tcaattggca aaaattgctg ttacgggtga
    34501 aacctcagca gctcgtcaaa tggtagttga acaagaaaca acaaacacat atgagagcta
    34561 tgaagcacct gaagaaacaa tctacgatga gccggaacca aaagagtccg gagaaaatgt
    34621 aaaaaataaa atcaagggtt tctttacaaa tatttttgat taattcatcc tgggaggaat
    34681 aagatatgga attctcaatt gataataata tcaatgacgg cgcagtaatc aaagtcatcg
    34741 gagtcggtgg tggcggtgga aatgctgtaa accgaatgat tgaagaaaac gttaaaggtg
    34801 ttgaattcat tacagccaac acagacgtgc aagcattaaa aaattcaaaa gctgaaacag
    34861 ttatccaatt aggccccaaa tatactcgtg gtttaggtgc tggttctcag ccagaagttg
    34921 gacaaaaagc ggcagaagaa agtgaacaat ccttacgcga agctttagac ggtgcagata
    34981 tgattttcat cactgcagga atgggtggag gaaccggtac aggtgctgca ccaatcgttg
    35041 caggtatcgc gaaagaattg ggcgcattga ctgttggtgt cgtgacacgt ccattcactt
    35101 ttgaaggacc gaaacgtggc cgttttgctg cagaaggtat cgctcgtttg aaagaaaatg
    35161 tggatacatt attaattatc tcaaataacc gtttattaga agttgtagat aaaaagacac
    35221 cgatgcttga agctttccgt gaagcagata atgttttacg acaaggtgta caaggtatct
    35281 ctgatttgat cacagcgcca ggttacgtta accttgactt tgctgacgtg aaaacagtga
    35341 tggaaaacca aggtacagca ttgatgggga tcggtgtggc tagtggagaa gatcgcgtag
    35401 tagaagcaac gaaaaaagca atctcctctc cattgcttga aacatctatt gatggagctg
    35461 aacaagtact tcttaacatc acaggcggtt tggatatgac attgttcgaa gcacaagatg
    35521 cttcagatat cgtagcaaat gcagcaactg gcgatgtaaa tatcattcta ggtacatcta
    35581 tcaatgaaga aatgggcgat gaaatccgtg tgacggtcat cgcaacaggt atcgatgaat
    35641 caaaaaagga acgcaagtct agccgaccag ctagacaagc acaaatgcaa tcacctgctc
    35701 aaaagactgt attagatatg gatcaagcta aaccaacttc ttcagaagaa gaaaacagtt
    35761 ttggcgattg ggatatcaga cgtgaacaaa atgttcgtcc tagagttgat gattccaatt
    35821 ttgacaatat cgaaaaaaaa gaatttgata cattcaaccg cgaagaaaca aaatctcatg
    35881 gcgatgatga attaaatacg ccaccgtttt tccgtcgtaa aaaataaagg agaggaagag
    35941 cacatgattg ctgacaactt gcagaaaatc aagcaagaaa ttcaggattc gtgtgctctt
    36001 gttcatcgtg atccgaaaga agttacatta gtagctgtaa caaaatctgt tgaatccgct
    36061 caagctgaag aattggttag agctggcgtt atgaattgtg cagaaaaccg agtagataaa
    36121 ttattagaaa agaaacaaga tttatttgat tttcctgaaa taaagtggca tttaattggt
    36181 aatttacagc gcagaaaggt aaaattgatt gtaaatgaaa ttgattactt tcatgcgttg
    36241 gacagtttaa gattagcaga agaaatccag aagcggttag agaaagaatt atcctgtttt
    36301 attgaagtaa atgtttctgg tgaggaatca aaacatggaa tttcaccaga tgagctttta
    36361 ccgtttgtgg aatctttagc tgcctgcaca aaaatcaagg ttgttgggtt gatgactatg
    36421 gcgcctaaag aagcttctga tgagcaaatc cataaagtgt ttggtacgct gaaagaattg
    36481 cgtgatcttg ttcaagcaaa aggttatgcc catgcaccat gtagtgaatt aagtatgggg
    36541 atgagtcaag actttcaaat tgcgattgaa gaaggtgcaa catttatccg tgtaggaaca
    36601 gcgctattca aagacgaata aaggaggaac aaaaatgccg cttttaaaca gaggagcaat
    36661 tgctaatttt ttcggattag ctgatgagga agagtacgaa taccaagatt atcctgaaac
    36721 aacaaaaaag gctgtacagc caactaaaaa aaatacaaca cagaatcaat caactcattc
    36781 tgtatctgct gcgaatactc atgaaaaaca aaaaacggcg acttcacgtc ctgtaacgca
    36841 tgaaagtatt cagccggctg aaaagaaaaa agtaattgaa ctacatcaat cacctacaaa
    36901 aactgtagcg aaagaaagaa cagcttcaag aacctctaca caacctaaag caaatcttgc
    36961 tggaaaaatc actgtaatgg aaccaagagc ttattctgaa gctatggcga ttgctaaacg
    37021 aatcattgct ggagaagcaa ccttagtgaa ttttcattta gtagaagaaa aacaagcgag
    37081 aagaatcgtt gattttctaa caggaacagt ttatgcacta gatggagata tcaaacgtgt
    37141 tggagatgag atttttcttt gtacaccgac tgggatggag attgacagtt caaccgctca
    37201 atcttttgca gatgcgaatt tgtttgatct gtaagaggag gaactacgat ttatactatt
    37261 gcactattac ttcatttact tcaacgggca gcctatttct atagcattat cttgatggta
    37321 tatgcattgc tctcttggtt tccaggcggg tatcaatcag ggctaggacg attattagct
    37381 aagatctgcg aaccgtatat cagtttgttc gatcgtctgc ctttgaggat tggacccttg
    37441 gatttcacaa ttttaggggc aatcctgatc ttgaacttag ccgtacaagg tttagcacag
    37501 atcgttatat ggataactgt ccatttagtt tattgattga agcaacaaaa tctttattct
    37561 cagaatagat aggaggggaa aattttggat gcaaatgtat accagcactt tcgggcagat
    37621 gaacgtacat ttatcgattc ggtaggcgat tggattgaac aggttcaagg acaatatgca
    37681 ccctatctga ccgaatttct tgacccaaga caatcctata ttttagaaac actgattcga
    37741 caaagcagtg atttgcgttt catgttttat ggcggatatg aacaggcaga aagaaaaaga
    37801 tgtttgattt tccccgatta ttacgaacct gtagaggaag attttgaaac agcattgtat
    37861 gaaatccatt atcctagcaa atttgccagc ctaagtcatg ggaaaatcct tggaacttta
    37921 gtgggaacgg ggatcaaacg ctcttacttt ggcgatatca tctcggacgg tgatcgctgg
    37981 caagtattta ttgcaaatga ggtggatcat tttgttgctg cacaagtaac aaagattgga
    38041 aaggttgctg tacgcttgga accaatcaaa tacacagaaa tgattatgcc gaaagatagc
    38101 tggacacaag aaagaggaac agttagttcc atgcgactag acagtgtgat ctctgagatt
    38161 tataatattt ccagacagcg gtccaagcag ctgatcgaag ctggtaaagt aaaagtgaac
    38221 tggacagaaa atacaagacc tgattttgta cttgaactat tagatattat ttcagtcaga
    38281 ggttatggca gagtccagat ccaagaactt gaggggaaga cgaaaaaaga aaagtacagg
    38341 gtactgttcg gtgtattacg taaataaaat aaaaaggtgg tttactcatg gctttaactc
    38401 cattagatat ccaaaataag acattcccga caaaaatgcg gggatataat caagacgaag
    38461 tagatgattt cttagattta gttgttcgtg actatgagga attgactcaa agaaatcgag
    38521 aattagaaaa agcagtcaaa cattctgaag aaaaacttga gtacttcaat gaattaaaag
    38581 atgctttgaa ccaatcaatc atcgtagctc aagatacggc tgataaagta aaaacaagtg
    38641 caagcaagga atccgaagtg atcgttactt ctgcacaaaa caaagcagat gagttagttg
    38701 cgaacgctga aaaacgtgca catcaattaa caactgatgc agaagaaaaa gcaagaaaaa
    38761 tcttgacaga tgcaacagaa aaagcaagac agcttgcgac agaaactgaa gatcttaaga
    38821 aaaaaacacg agtattccat caacgtatca gcttgatgct tgagtctcaa ttagaacaag
    38881 tgaaaagtcc ggaatgggat gaaattttac aaccattctc cagctacgtg actgacagcc
    38941 atgaagtgat caaagaagtt ttagcaaaac agcttgacaa tgaaaatgat actgatgtaa
    39001 actcagacac aggagtcata gaagcaccta tgacggcatt tgatacacag gctattgata
    39061 tctcgatcgt gcctggtgaa aatgaaaacg agtagaacag aaaagcactt tgttattctt
    39121 aaagcgagcc gatgagagtg gaagttcggt aagacactgc atggtgaaag atcctctact
    39181 tgagacctgc ttttccgaaa ttagagtaag aagcagcggc tgacctcgtt attggtcaca
    39241 gagagtttgc actagataga tgcaactaaa tttgggtggt accacggcat gttcgtccct
    39301 tgcggctgaa catgcttttt tgtgtccgga aaacaaataa aggagtgtat ggttgaatga
    39361 aaatgaaaga aaccttgcaa ttaggaaaaa caaaattccc tatgcgtggt aatttgccaa
    39421 accgagaagg cgagtggcaa aaagaatggg aagaaaatcg aatctaccaa aaaagacaag
    39481 agttgaacga aggaaaacct agctttgttc ttcatgatgg acctccatat gccaatggta
    39541 atatccattt aggacattca ttgaataaaa tcagtaaaga cattatcatt cgttcaaaat
    39601 caatgtctgg ctatcgtgca ccatatgttc caggatggga tacacatgga ttgccgattg
    39661 aacaagtatt ggctaataaa ggcgtgaaac gtaaagaaat gtccatggca gaatacttgg
    39721 aaaaatgtcg tgaatatgca ctttcccaag tagataagca acgagcagat ttcaaacgcc
    39781 taggagttgc aggagattgg gaacatcctt atgttacatt agatccttct tatgaagctg
    39841 cacaagtacg cgtatttggt aaaatggctg aaaaaggcta tatttacaaa ggattgaaac
    39901 caatttactg gtctccgtca agtgagtctt ctttagcgga agctgaaatt gaatataaag
    39961 atgtaaaatc tccatctatt tttgtagctt tcaatgtcaa agacggcaaa gatattcttg
    40021 atgaagatac agcttttgtc atttggacga caacaccatg gacattgcca gcaaaccaag
    40081 gtattgctgt aaatccaaaa tttacgtatg tattggtgga agccgatggc cgtaagtttg
    40141 tcgtagcgaa agatttgcta gaaacagtcc aatcagaaat cggttgggaa aatgtaacag
    40201 ttctaaaaga atttgctgga caagaaatgg aatatatgac tgcaagtcat ccattctatg
    40261 aacgtgaatc acttgtgatt ttaggcgatc atgttacttt agacgctggt actggattag
    40321 tccatactgc tccaggacat ggggaagatg actatatcgc tggtagcaaa tataaactat
    40381 ctgtagtgtc acctgtagac tcaaaaggat tgtttacaga agaagcacct ggatttgaag
    40441 gtatctttta tgacaaagca aatcctatga tcactgatct attaaaagaa aaaggagctt
    40501 tgctgaagct agatttcttt actcatagtt atcctcacga ttggcggacg aaaaagcctg
    40561 tgatctatcg ggcaactcca caatggtttg catctatcga taaattccgt cagaatattt
    40621 tggatgaagt agaaaaagta gagtgggtta tcccatgggg taaaacacgt ttgtataata
    40681 tgatccgtga ccgcggcgat tgggtaattt cccgtcagcg tgcatgggga gtaccacttc
    40741 cgattttcta tgctgaaaat ggagaagcaa tcatcacacc agaaacaatc gaacatgtgg
    40801 caaaattatt tgctgaacat ggatcaatta tctggtttga aaaagaagcg aaagaacttc
    40861 ttcctgaagg atttacccac ccaggttctc ctaatggcga atttacaaaa gaaaaagata
    40921 tcatggatgt ctggtttgat tctggttctt ctcatgaagc tgttttacgt cagcgaccag
    40981 aattatcatt cccagcagat atgtatttag aaggatcaga ccaatatcgt ggctggttca
    41041 actcaagtat cacgactagt gtggctatca atggtgtagc accatacaaa tcagttattt
    41101 ctcaaggatt tgctttagat ggtgaaggcc gtaagatgag taaatcttta ggaaacatca
    41161 ttgcaccaga aaaagtgatc aaacaatttg gtgcagatat ccttcgctta tgggtatcta
    41221 gtgtagatta tgaagcagat gttcgtgttt ctatggatat cttaagtcaa gtggcagaag
    41281 tatatcgtaa aatcagaaat acgatgcgtt tcttattagc gaatacagaa gatttcgatc
    41341 ctaaaaaaga tactgtttcg tacaatgatt tacgttctgt agacaaatat atgaccgttc
    41401 gattgaacca agtaatcaaa gaaatccgag aagaagggta cgacaaatat aacttcatgc
    41461 atatttaccg tacagttatg aacttcttga cggttgatct atcgtcattc tacctggatt
    41521 ttgctaaaga tgtagtttat attgaagcag aagatgatta tcaacgtcgt tgcatgcaaa
    41581 ctgttttcta tcaaacagct gtagctttga caaaattatt gactcctatc attccgcata
    41641 cagcagaaga aatctggtca ttcctgaaag aagaagagga gtacgttcag ttaagcgagt
    41701 ttcctggtta tgaagagttt gcaaaccaag aagaattgat ggatacctgg actgctttca
    41761 tggacttccg tgataatgtc ttaaaagcat tggaagaagc aagaaacagc aaattgattg
    41821 gtaaatcttt ggaagcaaaa ctaactgttt atccaaaaca acaagttcgt gaaatgttaa
    41881 aagctttgga tgcagatatt gcacaattat tgatcgtttc accagactac tttgaagtta
    41941 tggcagcaga tgaacaagtg ccagataacg ctatggtatt tgatgatgtt gctattacag
    42001 tggaaaaagc agacggggaa acttgcgatc gctgtcgcca agttcgtaaa gatgtaggag
    42061 tagatgaaaa acttcctcat ctatgcggtc gttgtgcaaa aatcgttgaa gacttctatc
    42121 ctgaagctgt agctgaagga ttcgaagaaa agtaaaaggg aaaagggggt gtgacatgtt
    42181 ctttgtcaca cccccttttg ttatcaatcg tttaattttc cacgttcacg ataccagtta
    42241 tctggttgcc agatccattc gaatccgtct ttttcaagta gttcgaaagc tgctttaggt
    42301 cccattgatc cagctttgta gttgggaaaa tccggttgtg tttggtccca agcttttcga
    42361 atgacatcca cgatatgcca agattgagcg acttcttccc aatgagagaa gttcgttcca
    42421 tcaccattca acgcatctaa tagtaatttt tcgtaagctt ctgggctatt ttcaaccatt
    42481 tctgcactat ttctaaattc caatttgatt ggttccgttt caaatccttg ccctacttct
    42541 ttcccattca aggataaaga aaatccttca gttggctgaa tatagatcgt tagaacatta
    42601 ggtggaagtg tcgtatcgtc acatggttca tcgacagatg ttttgaatac attaacagga
    42661 acttgtttga atacgatgtt gatccgagtc cctttttcag tcaaacgttt gcctgtacgt
    42721 acatagaaag gaacacctga ccaacggaag ttatcgatag tgaatttgcc tgcgacgaat
    42781 gtttcagtct ctgattgagc atccactttg tcttcttcgc gatagccctt gaattgtaca
    42841 ccatccaatt caccttgagc atattgcccg cgaacgaagt tttctaacac ttcttcttcg
    42901 ttataaatgc ggatagcttt caatgctttg atcttttctg tacggatttc tttttcggaa
    42961 aatgctactg gcggttccat tgcaagtaat gctacaacct gtaaaatatg attttgcacc
    43021 atgtctttaa gtgcgccact atgatcgtag tagcccccgc gatcttctac accgaggttt
    43081 tcgccaaaag taatttggat attgtcgata tagcgattgt tccattgagc ctcaaaaata
    43141 ttattggcaa aacggatagc tgagatgttt tggatcattt cttttcctaa ataatgatca
    43201 atcctgaaaa tatcttgttc tgggaatact tctctgattt gctggttcaa ttcaaaagca
    43261 gactggtaat cagaaccgaa cggtttttct atgatcaaac gattgaagcc attttttgtc
    43321 ataatatttt gtgatttcaa atgagaaacg atcgttccaa aaaattgagg tgccatagcc
    43381 aaataataga cacggttacc gtttaattga tagtgtccat ctaatcggtc agacaattct
    43441 tttaatgtct gataatgcgt tgaatcattt acatcatggg attgatagta aaaatggctt
    43501 gcaaaggtag ttgcttcttc atctgaagga ttcaatgcac ggattgtttc tttgacaact
    43561 tcacggtagt gctcatcgct ccagggacgg cgagcggttc cgattacagc aaaatgctcg
    43621 cctaaatttc cttttctgta aaggcggaac aaagacgggt acaatttacg ctgggctagg
    43681 tcacctgtac cgccgaatat cgtaaacaat acattttttt cattagacat gtggatacac
    43741 tcctttatat tttatcgaca aaaatcgtgc tggccgcctt aaagctgacg gggattttct
    43801 ttctatcatt ttggatagtg atcggtcctt cataagctgc gatgtcaacg atctcatatt
    43861 cttcgttgat attcaggtca atagtgacta agtaatccaa caattctttt tcatcaagca
    43921 ctcgtgcgat acgcactttt gtaccgacag gataggactc caatgtttgt cggcgttctt
    43981 catggacaac ttcctctttt ttaggaatcg atcctccatg aggacaatgt tcaggatgat
    44041 tcaaatagtt ttctaaatga tctgcaagat gttccgaagt cacatgttcc aatacttcag
    44101 catcatcatg gacttcattc cagctatagt ctaaatgttc aactaaaaaa acttcccata
    44161 agcgatgttt gcgaatcaga ctgctagctt tttgcagtcc gcttgcagtc aattgtacac
    44221 cttgataagg ggaatgttct acaagctctt ctttcacaag tttagaaatc atttcactga
    44281 cagatgcagc tgagacatct agactagata cgatttgttt attgttgact ttcgttgtat
    44341 ctccacctag ttctaaaatg attttcaaat aatcttctcg atttggtgtc atattcgatc
    44401 atcctttcat ggtaaaaaac catcattagt aagtgtaaca aaaaaaacgt taattgacta
    44461 tttttctaaa taaaaaacaa aggattttta gacgttttta caacaaaaaa cgaaagatga
    44521 tagagaagac tcattctttc gtttataaag gatatatata tacattggga gggatctatt
    44581 tttcagataa caacttatat gaagtgtctg cagattcgtc ataaagagtt tgttcgggat
    44641 aagaaaagat aagataaaaa ccatactgat cacgtacgac taaacgatat tcatctattt
    44701 ctaccacaga tgtgccaaga gactgaccgt tgatcaaaaa cgtgtaatca gatgtaatct
    44761 gtaattgttg tttttgctgg ctatcactaa agaaccatgt accttgatac tttgagagtc
    44821 cttctgactt ttccgcttgt tttttctttt tcaagtaaat aaaacttgag agaacggtaa
    44881 tgagtgaacc aagaaaatag atcatttttt ttatcaccaa atcactcctt tatgagaaaa
    44941 taatcgcata gacatattct ttcttcttta tttcattgta ccgaataaaa gctaaaattt
    45001 ctctaagact ttcgactggt ttttttactg tttttctaca aattatgata ggatacatag
    45061 taggaagaaa ggtgacataa tttgaagtat cagcaagtgg aaatagcttt ttttattgac
    45121 cgcccgaatc ggtttatagc acattgtatg aaaaaagacg gagaaataat tattgcgcat
    45181 gtcaaaaata caggtagagg aaaagaggtc ctgataccag gcgctgaagt ggctattgta
    45241 tttgctcctg gacctaaacg gaaaaccgcc tatgatctga ttgctgtaaa aaagaagggt
    45301 gactggttta atatcgatag tcaattgcct aatcggctgg caattgatgg tattttagac
    45361 ggcacgatcc ttttaccagg attaactggt ccatttacgg tatacaagcg tgaagtaact
    45421 tatcttcact ccaaatttga tatttattta gagacggtgg tcggacaaaa agcatttgtt
    45481 gaagtcaaag gtatgacact tgaaaataaa gcgattggtg cttttcctga tgcgcccaca
    45541 ctcagaggat tgaaacatat aggagaatta acgtatgccg cacaagatgg ttatgccgct
    45601 tatgtcttgt ttattgctca gttcgaacat cttcatctgg caacgatcca tgaagaaatg
    45661 caaccagcac tagctgatat ggttcgacat gcgcagcaaa gcggagttca aatcctcgcc
    45721 tataattgtc aagtatcggc agatgaggta actgtcaagc aggccattcc atttgatgta
    45781 gatatccctt ttgaagatcc tatacaatag aaagaaggta aaataatgat caacttaggt
    45841 attatcggaa caaattggat tactcatcaa tttgtccaag cagctttaag cacaaaaaaa
    45901 tatgaattga cagcggtata ttctagacat ttggaaaaag cacaggaatt tggttctcat
    45961 tatgaagggg atatcgaatt cgcaacagat ttgaagactt ttttcaatat tactcatatg
    46021 gacaccattt atattgcttc tccgaatagt cttcacttta gtcaagctaa gcaagcaatt
    46081 ttggcaggaa aaaatgtgat agttgaaaag ccagcttttt cgacgccaaa agaaatggat
    46141 gaaatcatcc atttggcaaa tgaacacaat gtgtattttt ttgaagcagc aagaaatatc
    46201 catgaatcag gttttaaaaa gattgccgat tacttaccat taaaagacga gataatcggt
    46261 gcaaatttca gctatatgaa atattcttcg cgctatgacc aagtattaga tggagaagaa
    46321 ccgaatatct tctcgactca tttctcaggt ggtgcattga tggatttagg tgtttacctt
    46381 gtatatgcag ctgttgcttg gtttggaatg ccaaaagaag tccattattt cccaagaaag
    46441 atttctactg gtgtagatgg tcttggatgg gggatcttac gttatgagaa ttttgatgta
    46501 tcgatccagc caggtaaaat cggtgattct tatttaccgt cagagattta ttttgactca
    46561 ggaacgctag tgatgaatgg agtcaatgca attgaacaag cacaatttca tgatcgcgcg
    46621 cataaagaaa tcattgattt ggcggtaaca gctgcagaaa atccaatggc agatgaagca
    46681 gaggattttg ccaatgtcat ggctcatccg aaagatccag cttggggatt gttgtatgaa
    46741 gagtggatcg agctagctag aaatgtgaac caagtgattt atgatttaag aaaaaatggc
    46801 ggcatcaaat tcgatgcaga taatgaggaa gatttttaat gaacgaattt gtacaagtat
    46861 ttcccgaaaa ttggcagaaa aaatatgagg ataaagggtt tatctcacct tctcttattc
    46921 aacgagcagt ttttcagcca ctaagtaata aacaaagtat agtagcggtt tctcctacag
    46981 gttcaggtaa aacactggct tatctttggc ctctactact aaacgtggaa ccaggtgaag
    47041 caagtgcgtt ggtcattttt gcttcttctc aagaactagc tattcaagta gcagatgttg
    47101 cacgtgaatg gggaaaagac aaagagttga aagtccaatc tttggtgggc ggagccaacg
    47161 tcaaacgtca gattgagggt ttgaaggaaa aaccagaaat cttgattggt acaccaggaa
    47221 gaatattgga attgatgaaa gcaaaaaaaa taaaagcaca tcaagtgaaa acaatggtat
    47281 ttgatgaagc agaccagcta tttgacgctg ggaacagcca aatcattgat caaattcttc
    47341 atcaagctcc aacagagtat cagctagctt ttttttcagc gacagcagat cgttcccttg
    47401 aaagcattga aaaaatcact gggaaaacgt ttgagacaat tgacgtgaca gcagaggacg
    47461 attctcgaaa aggactgaga cattactttt tacgtgtacc gatacgaaag aaagatgact
    47521 acttgagacg tctcacgcat atagaagatt ttcatggtct gattttcttt aatcaactga
    47581 ctgaattagg cgtaatggaa gaaaaattgc tgtatagagg tgtaccggta ggaagtctgg
    47641 cctctgatca gaacaagcta ctccgaaaag cagcgctaga acaattcaaa aagaaaatgg
    47701 tcagagcact tttgaccaca gatgtggcgg ctagaggttt agatattaca ggtcttcctt
    47761 atgtagtgaa tgcagaagtt ccgttaagtg aagaagctta tttgcatcgt tcgggaagaa
    47821 ctggtcgaat gggtaatgaa ggaatagtaa ttacactcgt acaagataat aatctaagag
    47881 atttaaaacg gcttttacgt ccatcaaata taacacttga agagattttt ttatacggag
    47941 gtaagctgca aactgagcag ccaaccaaag aagatgcagc tcctgcagta aataaaaagt
    48001 atgcgaaaac tttttctgga aaggagcaga acccagaata taacaaagaa aaaataagaa
    48061 aaaaagttaa aaataaatca aaaaaagaga gaaataaagg agcaaggcgc aaataagcgc
    48121 ctttttatgc tatgattatg aaaacgggaa caaaattggt tgccagagga ggggttatgt
    48181 gaaagaacgt caagaagaga tcttgcagct attgacagaa aaccaacaag gattgacagc
    48241 aagtgatgta gctgagcgct taactatcga tcgaagcaat gcaagccgat atttaagtga
    48301 actatacaag gcccatcata ttgtaaaaac cgctggccga ccagtcgttt actctttgcc
    48361 aacggaaaag tcaaaatctg atgaagtgca tgtcgactct tctacgcaag tgacttttga
    48421 aacactcgtt ggagaaaatg attctttaaa agtcagcata cagcaggcaa aagctgcgat
    48481 tctttatcca ccgcgggggt tgcatacgat tatttttgga gaaactggta cagggaagtc
    48541 gatgtttgct gaatgtatgt atcattttgc aatcgattca gagatgcttt ctgcagatgc
    48601 gccatttgtt tctttcaatt gtgcggatta tgctcaaaat ccgcaactgc tctttggaca
    48661 catctttggg atcaaaaaag gggcttacac aggagcagct caagatagtc ccggtctaat
    48721 agccaaagca gacggcggta tattgttttt agatgagatc caccgtttac cgccggaagg
    48781 gcaggaaatg ctgtttactt tcattgataa aggtatttac cgtccgcttg gagaaagtgc
    48841 acaagtacat gaagcatctg ttcagatcat tggggcgacg actgaatctt cagaaagttt
    48901 cttatctacg ttcaatcgac ggattcctat ggcaatcacc ttgccgaatc ttgcttcacg
    48961 ttcactggat gagcgttatg aaatcatctc tctttttatc aaacaagaag cgaatcgttt
    49021 gaatcaacgt atcgatatcg aaaaagaagc gattcttgcc ttcatgcttt atgatgcgga
    49081 aggaaatatc ggtcaagtga aacgagactt gaaactagtc tgtgcaaaat cttttttaca
    49141 ttaccgtact catcatgaga aaaagctaat cattcgaaaa gaagaacttt cccttcaagt
    49201 acaaaaagga ttactgaaaa tcaaggaaat accggaacgt ctcgaccgat tcatggacag
    49261 caaaagtcag tatttgacat ttgaaccagg atttgctgat gttgtctggt cacaagatcc
    49321 agaacgaaac atgcaggtct ataacgatat tgaggaaaaa gtcacttctc tttccgaaac
    49381 cggtgtggag aacattgatc tagagaccct catttcaaaa gatgtggatg cttatttcca
    49441 gacatatgtc aaagaattga ctaaaagttc gattcccaaa gatcttttgc cagatgaaat
    49501 ctggcggtta accaatcaat tgtatgatgt ggctgaaaaa cggttagacc gtatttataa
    49561 tgaaaaagct cgttttgctt ttgctttgca tctgcaaagt acattggatc gtgtgagaga
    49621 aggtcatatg atcgtccacc cagatttgaa taacgtacgg aaaaatttta agagggaatt
    49681 ccaggtagca atcgatcttt caacgatcat tgaagaagaa gaacaagttg agattccttt
    49741 tgatgaaatc ggctttatta gtatgtttct ttctatcaat ctaggagaaa gtgagcctgt
    49801 taaagaaaac aaagtagatg ttctcatatt gatgcacggc agacagactg cttcaagcat
    49861 gttggagatg gcacaagaac tattaggaac aaaagtaggg aaagctttta atatgccact
    49921 ggttatggaa gttcaaacaa tgtatgaaga agtgttacaa tatgtcaaaa actatcaaga
    49981 gcatttgacg aatggcctac tcttgttaac agatatggga tcattaaaca ccttcagtga
    50041 tttgatttat gaagagactg gcattcggac gaaagctatc acgatgacaa gtaccatgat
    50101 tgtgatagaa gcgatacgga tggcaagtgt tggaagaagc ttagaagata tttatcaaaa
    50161 tatccagctt tcctttgaat cgatcgtacg tgatcagttc aaagcggaaa agtctgaaac
    50221 tttacagcgt aaaaaagccg taatcgtgac atgctttact ggtgaaggag tagctgccaa
    50281 attatatcag cgtattatgc cagtgattaa tcaaaataag gtagaactga tccagatgca
    50341 gtttttagaa cgtgaatcat tcaaaaaaca catcgatgcc ttattggaag aatatgagat
    50401 caaagcaatt gcgggaacag ttgatgttga ttatcaaaat atcccatttt tttcagccta
    50461 tgacgttttt gatgatgaaa aactaaatat tttaaagcgt atagctgatg atgagatccc
    50521 gacagctaaa attgtcgatt cacttgctgg atcattaagc gatgtctttt ctattgatga
    50581 actgatccgt tcattgcaaa agacagttca gcagatccag accgatttgt cgattatcgt
    50641 ggaacctgga gtagatactg gaatcgttat ccatttagcc ttcatgttag acggattgat
    50701 caaacaagaa agccatcggc aatttgagaa actgtctatt ttctcaaaaa tttatcgttt
    50761 ggaaatggat atcgttcggg caaacttgat ggcactagaa cgaaaatatc aggtaaaaat
    50821 tccagaagat gatatcgcat ttcttacaca aatgtttctt gaaaataaaa taaaaaaatg
    50881 aacacactaa tcatactgtt tacacactaa acatctgtgt gcgcactata aaaaagagct
    50941 aaaaagcatg aaaacgctat ttcagctctt ttttttattg gcatgcttct tgcgttatat
    51001 aaaagtgtaa aaaaataaaa ggagtgttaa aaatggcaaa aaaaacaatc atgttagttt
    51061 gttcagcagg gatgagtacg agtttattgg tcacaaaaat gcaaaaagca gcagaagaaa
    51121 aagggatgga agccgatatt tttgcggtct ctgcctcaga tgcagataat aatttagaat
    51181 ctaagaatgt cgatgtatta ttattaggtc ctcaagtacg tttcatgaaa gctcaatttg
    51241 aacaaaaact tgcgcctaaa ggtattccat tagatgtcat caatatgcaa gactatggca
    51301 tgatgaacgg agaaaaagtt cttgcacaag cagaaaatct aatgaaataa atcaagtatg
    51361 cagttggggg tataacaacg tggaagatca acaaaatcta gaagccatca tggggttaat
    51421 catgtttggc ggtaatgcaa agagcgatgc aatggaagcg attgcggctg ctaaaatcgg
    51481 tgattttgag ttagcggata ggaaaatcgc tgatgcagaa gaatcactta tacaagcgca
    51541 tcatgcacaa acagacatgt tgacacaaga agcacaagga aatcatatgc aagtgacatt
    51601 attgactgtt cacagtcaag atcacttaat gacatctatt gcgtttactg atttagcaaa
    51661 agaaatcatc gaactttatc gtcgcgtata cagcgaataa atacaacttc ttttttgaac
    51721 ggaagaagaa aaatttttga acggattttt tattttgtta taaggagaac tctctttata
    51781 taaaaaactt ataggaggaa gtaaaaaatg aacggactat caagttggat ggagaaatac
    51841 atcctgccgg ttgccgcaaa aatcggagcg caaaaacatt tagttgcttt gcgtgatgct
    51901 tttatcggca tactgcccgc aacaatggcg ggatcagtcg ctgtaatgat caatgcaatt
    51961 attcgtgatt taccgcaaca gtttaacagt acctatgctg acagtttagc agcagacaaa
    52021 ggaatctttg ccgtattgaa tgtcatcatc ggaatcaatg gttttgtctg gaacggtaca
    52081 ctagcaatcg ccggattgat ctttgccttt tcttgggggt ataatcttgc ccgagcttat
    52141 ggagtaaatg atctagctgg ggggatcgtt ggtttagcta ccttgattca aggtatttcc
    52201 tttggtccag cattatcagc agcattagat gtgaatgttc cttcaaatgt cgcagatgca
    52261 atcaatagtt ctgagattgg tgcaacgatt gcagatggca cactgtcagt tggattatgg
    52321 ggttggctaa aactagatca tttgaatgga aacgcttatt ttacagttat gatcatggga
    52381 gctatttcag tcattatttt ttgtaaattg atgcttgcca acattacgat caaaatgcct
    52441 gattcagtac caccagcagt atctaaagca tttgcagcca ttttaccagc gacgatcgct
    52501 ttatacgtca ttgctattat caattatatc gtaggtcgtg tagctgatgg gcaactgatc
    52561 attgatttgg tgcaaaaata tattgcagaa ccattcctag gattatctca agggttggga
    52621 gcagtattga tcgtcacagt atttgttcaa gtattctggt tctttggtat tcatggatca
    52681 aatgtattgg caccagtgct agagggaatc tggggacaag cacaactaat caatattgat
    52741 attttccaaa aaggttataa cggaaaaact ggtacaccag ccgtgttaga tgcaatcgaa
    52801 gatggaaaag cttatatgtg ggtccgcgga tcgttcgatg cttttgcatg gtttggcgga
    52861 tcaggcggaa cgatcgtctt actgatagct atcttgattt tctctaaacg tgcagattat
    52921 ctaacagtag ctaaattatc cattgggcct ggtatcttca atatcaacga accagtgatg
    52981 tttggtctgc caatcgtatt gaatgcaatc atgtttatcc cattcttgat tgctccagta
    53041 gtagcaacag caattggatg gacagctact tatcttggcc tagtcgctcc ggtatcgcag
    53101 caagtcacat gggtagtacc gccgttctta ttgtcattct tagcaacagg agcggattgg
    53161 cgggcaccga tcgtaacatt agtatgtatg gtcgtgactt tcttgatttg ggcaccattt
    53221 gtcatctctg caaacaaaat ggaccctgcc gcaggcgaac aacaataaga tgaacgtgag
    53281 gagcgggacg ctttaagttt cgttcctcat aatgaatttt cgaggaggaa ctgaaatgat
    53341 tacaattgcc agtgcaatgc aacaagatga aatcaaagaa ttgttagaag gatacaatga
    53401 agaaggaatg acttttacat ttaaagaaaa acaaggaatc aagctgttct ttgaaacaag
    53461 tgcagaagat ccggaagttg cggctaaaaa agcaaaggaa ctaatcaaag cacagccttg
    53521 gggaacagtc ctttattttc aatcaacagc tgtttagaaa atggtttaaa aagataggat
    53581 ggttgagatg ataaaaaacg gtttattttt atgtagtatt ggttctttga tcgtgttgta
    53641 tagtttgaat ccacattcgc aaaggtatga tttgtatagt atggtcacag gtctttttct
    53701 aacaggatta ggaatctatt tcttcatgaa ggggaaaaaa agagaagaag caaaggagaa
    53761 aaataactaa tggaaatcac gaaaaaatta aatattccag catcgttttt ttacgataaa
    53821 gttatggact ctgtcctttt cgatgtacgt aaagcgaccg gcaaatcagt aactagaaaa
    53881 cagctgaaaa atttggagta cgtcaaacaa ttctcgcaaa ataaccgggc tcgcataaaa
    53941 atcgaagaag tcattgaaaa ccagtcttat aagtttcgta catcgacaac gaagaatgaa
    54001 ttcgtcgttc attatcaaat caaaccattg gacgattcga cctgtgaggt tcattacaca
    54061 gaaaaaatgg agtcttatgg catgcttcaa aagttgaatg atatgctttt aggaacaatc
    54121 ttgatgtatt ttaaacggag acgtttcaaa aaaatgctag atatgatcga agcaacgtat
    54181 taaatcaatg aaacatggta ctatttagtt attgaaaaat gaagtaagct agaaggaatt
    54241 tttcatagga agatagatct ttcctgcgaa tcctcactag cttttttgta ggaaggggca
    54301 gcaaaatgac aaacaaagta agagagctag gtgtatcttc gattgaggaa atgtttgatt
    54361 tagccactta tgcatttaat ggggcagata cacctgaaag gcgagaacgt tttcgtacac
    54421 ttgcggagaa ttcttggaat tacggatttt ttgatgagga ggatcggcta acaagtcaag
    54481 tcatggcgac cccttttcca gtgaattttt acggacaaga gtacctaatg gccggcattg
    54541 gctatgttgc ttcttatcca gaagcaaggg gacaaggcgg gatcaatcag atcatggaaa
    54601 agatccttga agattgccgt gatcgtaaag taagcttatc ttatctggcg ccattctcct
    54661 atcccttcta tcggcgctat ggctatgaac aatcatttga taaaatcagt tatcaactaa
    54721 acagtcgtga tgtgccgttt atcaaaaaaa aatctggaaa aataaagcgt atggattttg
    54781 aagatgcaaa agctgcaatc agaagaattt atgaacagat gccggaaaac caacgagctg
    54841 gtctgaagcg cgaagactgg tggtatacgt ataaattcaa gcaaaaaggc aattaccagt
    54901 ttgctttgca ttttgatgat aatgaggaag caacgggata tatcgtttat cagcttgcaa
    54961 cgtcttcctt tattattgcg gagtggggat ttttggatca tgatgctttt tgcagccttg
    55021 ttcgcttcgt aagttctcac aatggtgctt ttgaaacatt tgaatattca tgcggctacg
    55081 gcggtaatga tcaaaattat ctattagaaa atccatttgc ttctgtaatg atcacacctt
    55141 atatgatggc gaggatcgta gatatttctt tgtttttgga aaattatcca tttaaaaaga
    55201 gacaagctgc atttgcccta caaatagaag aagatcatta tgcgaaatgg aatgaaggaa
    55261 tcgtggaagt aacaatcgaa aatggaaaaa atcatctctc aaaagtagaa caaacaaaac
    55321 tcccaatcgt tcgaggaagt atccaacata tcacgcagct attattaggg tatcgtaaag
    55381 tggaagagtt ggtattccaa gaaagaatac aggtgacaaa agaatatgaa gaaacgttaa
    55441 gctcaatctt gccacagcaa cagccaattc ttaatgacta tttttgataa aaaacgggtg
    55501 atgacaatat ttttgtcacc acccttttgt ttttcatttg gcatttgaag gaaaatgtta
    55561 aagtaaatcc tcttttttcg taaatttgaa ttttttgttt tcttttgttt tagggttttc
    55621 ttttttgtgg tcttggattg cttctttcgt aatcttttcc cgattttttt tagatgaatc
    55681 taagcgttct gcgtatactt tttcttttgg cttatcattc attggaaagg acctccctac
    55741 attatttcat tctacctcta gtttatcatc tgttaaggac tagtggaaac gttttgccta
    55801 acttataagc tgattttttt agcagataag cttgcaagta aaaaacaaac aagctacaat
    55861 tgatttattg aaattgttcc tgtagctcag taggatagag caatcgcctc ctaagcgata
    55921 ggtcgctggt tcaattccag tcaggaacgt ataaataacc cctgtatcct ttgcggtaca
    55981 ggggtttgtt ttgtatttgt gccaaaaatg tgccaaacta gttatcattt ttatataaac
    56041 tatcgaacac agtattgatt ttttctttat cctgatcttc aagctctcga acaatatgaa
//
LOCUS       DADVXE010000013        55608 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.013, whole genome shotgun sequence.
ACCESSION   DADVXE010000013 DADVXE010000000
VERSION     DADVXE010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 55608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.013"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            139..996
                     /locus_tag="KB913_000833"
     CDS             139..996
                     /locus_tag="KB913_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBB6819215.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1111..2031
                     /gene="pstC"
                     /locus_tag="KB913_000834"
     CDS             1111..2031
                     /gene="pstC"
                     /locus_tag="KB913_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBB6819216.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2031..2915
                     /gene="pstA"
                     /locus_tag="KB913_000835"
     CDS             2031..2915
                     /gene="pstA"
                     /locus_tag="KB913_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBB6819217.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2930..3736
                     /gene="pstB"
                     /locus_tag="KB913_000836"
     CDS             2930..3736
                     /gene="pstB"
                     /locus_tag="KB913_000836"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBB6819218.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3752..4510
                     /locus_tag="KB913_000837"
     CDS             3752..4510
                     /locus_tag="KB913_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBB6819219.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4523..5200
                     /gene="phoU"
                     /locus_tag="KB913_000838"
     CDS             4523..5200
                     /gene="phoU"
                     /locus_tag="KB913_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBB6819220.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5438..5737
                     /locus_tag="KB913_000839"
     CDS             5438..5737
                     /locus_tag="KB913_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819221.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5763..6470
                     /locus_tag="KB913_000840"
     CDS             5763..6470
                     /locus_tag="KB913_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBB6819222.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6467..7234
                     /locus_tag="KB913_000841"
     CDS             6467..7234
                     /locus_tag="KB913_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBB6819223.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7334..8902
                     /gene="liaX"
                     /locus_tag="KB913_000842"
     CDS             7334..8902
                     /gene="liaX"
                     /locus_tag="KB913_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBB6819224.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9199..9519
                     /locus_tag="KB913_000843"
     CDS             9199..9519
                     /locus_tag="KB913_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBB6819225.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9519..9869
                     /locus_tag="KB913_000844"
     CDS             9519..9869
                     /locus_tag="KB913_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBB6819226.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10036..10974
                     /locus_tag="KB913_000845"
     CDS             10036..10974
                     /locus_tag="KB913_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBB6819227.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10989..11819
                     /locus_tag="KB913_000846"
     CDS             10989..11819
                     /locus_tag="KB913_000846"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBB6819228.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11863..12888
                     /locus_tag="KB913_000847"
     CDS             11863..12888
                     /locus_tag="KB913_000847"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBB6819229.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12903..13841
                     /gene="galU"
                     /locus_tag="KB913_000848"
     CDS             12903..13841
                     /gene="galU"
                     /locus_tag="KB913_000848"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBB6819230.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13966..14406
                     /locus_tag="KB913_000849"
     CDS             13966..14406
                     /locus_tag="KB913_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBB6819231.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14409..15011
                     /locus_tag="KB913_000850"
     CDS             14409..15011
                     /locus_tag="KB913_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBB6819232.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15079..16185)
                     /locus_tag="KB913_000851"
     CDS             complement(15079..16185)
                     /locus_tag="KB913_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBB6819233.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16395..17396
                     /gene="ccpA"
                     /locus_tag="KB913_000852"
     CDS             16395..17396
                     /gene="ccpA"
                     /locus_tag="KB913_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBB6819234.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17699..20044)
                     /locus_tag="KB913_000853"
     CDS             complement(17699..20044)
                     /locus_tag="KB913_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBB6819235.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20323..21225
                     /locus_tag="KB913_000854"
     CDS             20323..21225
                     /locus_tag="KB913_000854"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBB6819236.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21438..23213
                     /locus_tag="KB913_000855"
     CDS             21438..23213
                     /locus_tag="KB913_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBB6819237.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            23470..24687
                     /locus_tag="KB913_000856"
     CDS             23470..24687
                     /locus_tag="KB913_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBB6819238.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLCSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKEALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(25134..26720)
                     /locus_tag="KB913_000857"
     CDS             complement(25134..26720)
                     /locus_tag="KB913_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBB6819239.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            26971..27195
                     /locus_tag="KB913_000858"
     CDS             26971..27195
                     /locus_tag="KB913_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBB6819240.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            27337..29088
                     /locus_tag="KB913_000859"
     CDS             27337..29088
                     /locus_tag="KB913_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6819241.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            29088..30872
                     /locus_tag="KB913_000860"
     CDS             29088..30872
                     /locus_tag="KB913_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6819242.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            31330..32181
                     /locus_tag="KB913_000861"
     CDS             31330..32181
                     /locus_tag="KB913_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6819243.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            32278..34164
                     /locus_tag="KB913_000862"
     CDS             32278..34164
                     /locus_tag="KB913_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6819244.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(34205..35107)
                     /locus_tag="KB913_000863"
     CDS             complement(34205..35107)
                     /locus_tag="KB913_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6819245.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            35337..36740
                     /locus_tag="KB913_000864"
     CDS             35337..36740
                     /locus_tag="KB913_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6819246.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            36737..38173
                     /locus_tag="KB913_000865"
     CDS             36737..38173
                     /locus_tag="KB913_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6819247.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            38318..39244
                     /gene="trxB"
                     /locus_tag="KB913_000866"
     CDS             38318..39244
                     /gene="trxB"
                     /locus_tag="KB913_000866"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBB6819248.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            39457..41184
                     /locus_tag="KB913_000867"
     CDS             39457..41184
                     /locus_tag="KB913_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBB6819249.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            41200..41550
                     /locus_tag="KB913_000868"
     CDS             41200..41550
                     /locus_tag="KB913_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBB6819250.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAIIQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(41634..42494)
                     /locus_tag="KB913_000869"
     CDS             complement(41634..42494)
                     /locus_tag="KB913_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBB6819251.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            42586..43014
                     /locus_tag="KB913_000870"
     CDS             42586..43014
                     /locus_tag="KB913_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6819252.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            43176..43352
                     /locus_tag="KB913_000871"
     CDS             43176..43352
                     /locus_tag="KB913_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBB6819253.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            43379..43825
                     /locus_tag="KB913_000872"
     CDS             43379..43825
                     /locus_tag="KB913_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBB6819254.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(43981..45360)
                     /gene="brnQ"
                     /locus_tag="KB913_000873"
     CDS             complement(43981..45360)
                     /gene="brnQ"
                     /locus_tag="KB913_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBB6819255.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            46066..47037
                     /locus_tag="KB913_000874"
     CDS             46066..47037
                     /locus_tag="KB913_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBB6819256.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            47061..49253
                     /locus_tag="KB913_000875"
     CDS             47061..49253
                     /locus_tag="KB913_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBB6819257.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            49270..49746
                     /gene="ybeY"
                     /locus_tag="KB913_000876"
     CDS             49270..49746
                     /gene="ybeY"
                     /locus_tag="KB913_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBB6819258.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            49730..50125
                     /locus_tag="KB913_000877"
     CDS             49730..50125
                     /locus_tag="KB913_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBB6819259.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            50140..51039
                     /gene="era"
                     /locus_tag="KB913_000878"
     CDS             50140..51039
                     /gene="era"
                     /locus_tag="KB913_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBB6819260.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            51182..51994
                     /gene="recO"
                     /locus_tag="KB913_000879"
     CDS             51182..51994
                     /gene="recO"
                     /locus_tag="KB913_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBB6819261.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            52378..53295
                     /gene="glyQ"
                     /locus_tag="KB913_000880"
     CDS             52378..53295
                     /gene="glyQ"
                     /locus_tag="KB913_000880"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBB6819262.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            53297..55372
                     /locus_tag="KB913_000881"
     CDS             53297..55372
                     /locus_tag="KB913_000881"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBB6819263.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT        18028 a         9950 c        11804 g        15826 t
ORIGIN      
        1 atagcataga aacttttaat gagatagttt tttttacaat tatgagaatt tattttgtta
       61 tttaatgatt ttgattcgtt ttcatcaagt aatgaaaatg ataaaataaa catactttag
      121 gattaaagga gatttctaat gaaaaaactt aaattattct taccaataat aggattagcc
      181 attcttttat caggctgttc aaagtggatt gatcgaggag aatccattac ggctgttggc
      241 tcttctgctt tacagccttt agtagaaaca gttgctgaaa cttaccagac agaaaatcct
      301 ggaaaattca tcaatgtaca agggggcgga agcggaactg gtttgtctca agtacagtca
      361 ggagcagtcg acatcggaaa ctctgatttg tttgcggaag aaaaatcggg gatcgatgcc
      421 tcagcattag tcgatcatcg agtagcagtt gttgggatca ctcctattgt gaacaaggat
      481 attggcgtaa aagacatcag tatggaaaac ctgaaaaaac tatttacagg cgagatcaaa
      541 aactggagtg aagtcggtgg aaaagatcag ccagtagtta tattgaaccg cgcttcagga
      601 agcggaaccc gtagcacgtt tgaaaaatgg gtattggacg gagaaacagc tgttcaggca
      661 caagaacaag attcaagcgg aatggtgcgc cagatcgttg ccgacacacc cggtgcaatc
      721 agctatgttg ctttttctta tgtttccgat gatgtagata cgttgaatgt taacggtgta
      781 gaaccgacag atgaaaatgt gacaacgaac aaatggacga tttgggcata tgagcatatg
      841 tacacaagag atcatccaaa aaaactgaca aaagaatttt tagactatat cttatctgat
      901 gaagtacaag ataacatcgt tggagaacta ggttatatcc ctgtttctca tatgaaagtc
      961 gaacgtgatt ggcaaggaaa tatcgttaaa gagtaatctt tacacaaaat ttacaaactt
     1021 agctaaactt ttacatgtta ttaaaaccaa attgatgttc aatttgtaca ctgagtgagt
     1081 atgttaaacc tgattaaggg ggagtcatct gtggaagatg tgaaaaaagt attattaaca
     1141 aaatcaaaac gttcaaaaat ggaacagcgt ggaaaattca tcagtttttt atgtatcgcg
     1201 ctgatcgtgt tggttgtatt atctattttt tattttgtag ctagtaaagg attggccacc
     1261 ttttttactg ataagatcaa tgtatttgat tttctgtttg gtacagattg gaatccaagc
     1321 caaatcggag caaatgggaa accaatggta ggggcattgc ctatgatcac aggttcgttt
     1381 attgtgacct ttttatctgc tatcgttgcc acgccatttg ccattggtgc agcagtattc
     1441 atgacggaga tctctcctaa aaacggaacg aagatcttac agccggtcat cgagctgctt
     1501 gtaggtattc cttctgtcgt ttatggtttt atcggtttat cagttatcgt gccttttgtc
     1561 agaagtattt ttggcgggac agggtttggt atcttagctg gtacatttgt gttgttcgtt
     1621 atgatcttgc cgactgtcac aacgatgact gttgatgcat taaaggcagt gccacggcac
     1681 tatcgggaag cttcattagc gcttggtgcc acaagatggc aaacaatcta caaagtcgtg
     1741 ctacgagcag ccgtgcccgg gattttaaca gcagtcgttt ttggtatggc tcgtgcgttt
     1801 ggtgaagcct tagctatcca aatggtcatc ggtaatgcag cattgatgcc aacaggactt
     1861 actactcctg cttctacatt gacgtccatc ttaacaatgg gaatcggaaa tacaatcatg
     1921 ggaacagttg aaaataatgt gttatggtca ttagcgctga tcttgctatt gatgtcatta
     1981 ttctttaata tcgtgatccg tatgattggg aagaaaggag agctgaaata atgaacgcaa
     2041 aacgctcaga taaaattgct acaggtgttt tatatatagt ttcggggatc atcgtattga
     2101 ttttagcagc tttactactt tatatcttag ttcggggaat accgcatatt tcatggtcct
     2161 tcttgaccga accttccaaa gcctaccaag aaggcggtgg aatcgggatc cagctattta
     2221 actcgattta tttgcttttg atcacgatga tcatcagttt tcctatttct ttaggtgcgg
     2281 gtatctatct ttcagaatat gctggaaaaa actggctaac agatgtgatt cgcacgtcga
     2341 ttgaaatctt gagctcgttg ccttctgtcg ttgtcggttt attcggtttc ttggttttcg
     2401 ttattcaatt ccagtatggt ttctcgatta tttctggtgc attggctttg actgtattca
     2461 acttgcctct tttgactaga acagttgagg agtctttaca agcggtccat tacacacaac
     2521 gagaagcagg attggcctta ggtttgtcac gctgggaaac agtgataaaa gtggtggttc
     2581 cagaagcgac accagggatt ttgactggtg tgatcctaag ttctggaaga atttttggtg
     2641 aagcagctgc attgatctat acggctggac aaagtgcacc tgcgttagat tttacgaact
     2701 ggaatccatt aagtgtttca agcccgatca gcattttccg tcaagctgaa acattagctg
     2761 tccatatttg gaagatcaat acagaaggca cgatgcctga tggtgtttct gtttcggctg
     2821 gcgcttctgc cgtgttgatc attgctgttt tactgttcaa cttcggcgct cgtgcgattg
     2881 gcaaacgatt ataccgaaaa atgacttcag cctaaggaga agaagcaaaa tgaaaaaata
     2941 taactggaat gaaacaaatg tcatcaccat gccaaaagag aaagaagtag cactatatac
     3001 ggatgatcta catgtctggt atggcgacaa tgaagcaatc aaaggagtgg atctggaatt
     3061 tgaaaaaaat aagatcactg cactgattgg tccttccggc tgcggaaaat ctacgtatct
     3121 tcgttcgttg aatcgaatga atgatgggat cgctaatacg aaaatcactg ggaaaatcat
     3181 gtatcaaggc gtagatatta atgcgcctca agtggatgtt tatgagatgc gcaaacggat
     3241 tggcatggtt tttcaacgtc ctaatccgtt cagcaagtcg atttatgaca atattacatt
     3301 tgctttgaaa cagcacggcg aaaaaaacaa aaagaaatta gatgaaatcg ttgaaacaag
     3361 cttgaaacaa gctgccttgt gggaccaagt aaaagacagc ttggacaaaa gtgccttggc
     3421 tttatctggc gggcaacagc aacgtttatg tattgctcgt gcgatcgcga tgaaacctga
     3481 tatcttgctg ctagacgagc cggcaagtgc tttggaccct atttcgacag gaacggttga
     3541 agaaacactt gtaaacttga aagaagacta tacgatcatc atcgtgacgc ataacatgca
     3601 acaagcagct cgtatcagcg actatactgc ctttttctat ctaggaaaag taatggaata
     3661 tgacaaaact aacaagatat ttaccagacc aaaaattcag gcaaccgaag attatgtgtc
     3721 cggtcatttt ggttaagacg gaggcctcaa catgacaaaa gaaattattt catctaaaga
     3781 tcttcatctg tattatggaa agaaagaagc actaaaaggg atcaatctaa gtttcaatca
     3841 aggggaaatc actgcgatga tcggtccttc tggttgcggg aaatccactt atctgcgttc
     3901 tttgaaccgg atgaatgacc tgattccgaa tgtaacgatc accggaagtg ttttatataa
     3961 agacaaagac atctatggtc caaaaacaga tgttgttgaa ctaagaaaag aaatcggcat
     4021 ggtattccag cagccaaacc catttccttt ttctatctat gaaaatgtca tctatggatt
     4081 gaaattaaaa ggggaaaaag ataaaaaagt ccttgatcaa gtagttgaag aaagcctgaa
     4141 ggcagcgtct gtttgggatg atgtgaaaga caaattgcat aaaagtgctt tatctttatc
     4201 cggtgggcag cagcagcgtg tatgtatcgc acgtgttttg gcagttaatc cggaaatcat
     4261 cttattggat gaaccaacaa gtgcgcttga tcctgtttct actgggaaaa tcgaaagtat
     4321 gctgttagaa ttaagagagc ggtatacgat gatcatcgtg acccataata tgtctcaagc
     4381 ttcacgtatt tcagataaga cggcattctt tttagatggt cacttgatcg aatacaacga
     4441 tacgaagaag atattcatga atccagaaaa acaagagaca gaagattata tttcaggtcg
     4501 atttggataa ggaggaaacg gaatgctacg tacacaattt gaagaagaat tgctgaatct
     4561 ccataatcag ttctacgaaa tggggatgat ggtgagcagc gccgtgcaca agtcagttcg
     4621 tgcatacatc aaacacgata aaatcttagc ccaagaagtt atcgaaaacg atataaatat
     4681 caataacatg gaaacacgct tggagaagaa aagttttgaa atgatcgcat tgcaacagcc
     4741 agttacaact gatttgcgta tgatcattac ggtcatgaaa gctagctcgg atttagaacg
     4801 tatggccgat catgcggtgt ctgttgctaa atccacgatt cgcgtaaaag ggcagacgag
     4861 aataccggaa atcgaaaaag agatctccga tatgtccgat tatgtgaaaa aaatggtgga
     4921 caacgtccta gttgcttatg tcaaaacaga cgaaaaagac gcacgtacga tcgccaatat
     4981 ggatcaaaga gtcaatgact atttcaatcg aatctataat gcaacaatca aaaatatgca
     5041 ggaaaatcct gagacagtca tcagtggaac agactacttg aatgttgcca gttatctaga
     5101 acggatcgga gactatgtga caaacatctg tgaatggatc gtctacttgg ctacagggaa
     5161 aatcactgag ttaaatacga accacaatga gattttctaa actgaagctg tgattatgcc
     5221 gtttgtttag gaaaagaggt tgtgaaatca gcggttgtga aaaagctgtt ctgcatcaag
     5281 taataagaac agtcaaacaa aaaatagctc ctcatatttt tcgtttggct ggacttatta
     5341 ccgcagatgc aagcttttga acaccgttta ttcgggaaag ggtttgtgac aaaacatgtc
     5401 acaaaccctt ttcatcattt catagaaagg ataaagaatg caaaaaaaaa ttagcatcat
     5461 cactatattt tttatttgtg tgcttacttc atgggttatt cagcatcaag ctgctttata
     5521 tgaagtacct gtcatcgaga tcgaaaaagt acgaataaaa gaggatcatc aattgattac
     5581 aggaagactg atgaacacgg atcaaaaagg agaatcgatt tatttatcgg ttccttatca
     5641 aaaaaatcaa atagaaacag caaatataaa agcgagacaa atgtatctag tccaaatgca
     5701 tggagatgaa tggcagctag tagcaaaaaa aaaatgatgg ctggcttttc ttcttcacaa
     5761 gtatctccat tggcgccatg ttgcttattg gcggaaaaca gggtctattt gctttaggaa
     5821 gtctcatcat caatatcgtt ttacttttac ttttgttgct catctttact aaaacagaag
     5881 ggatttctct attaaatata tctatcctgt tcgtcgttat agggatgatt attagcatat
     5941 tggctttaga tggatggaat agaagcagta taatcaaaat ttcagctgca gttacgagtg
     6001 tttttttagc attttttatt tgtcttttga caatgaatca ttggaaagac caaggactgc
     6061 gctatgagga actgaattat ctgacacgac cgtatcgttc tgtttttctt tctagcgtac
     6121 tgattggaac agctggagga acactcgata ccgttatcac agtcattgcg acattagaag
     6181 aattgactaa gcgacaacca gaaataacag cgaaacagtt atggctttca ggaaggcaag
     6241 tgggtcgaga tgtgattggc tcgatgacca atatcctttt gttcgtctat atcagtgggt
     6301 cagttccatc gcttctttta tatttaggaa atcaatggtc gttcaaagaa acgatagaac
     6361 agcatttatc attggaattt ttacgcgtca ttgctggcag cttaggaata gtattatcga
     6421 tccctatctc ggtcctcttt tttctgactg taaggaggct gaaacgatga atgtacttat
     6481 tatacttgtt gggattttag caatcagcgt gctacttatt ggcggtacgc aaggtatgta
     6541 tattctttta ggcttattca tcaatttagg gatctttttc ctgttgttat tcggttatca
     6601 tcagaagtgg ccgatactgg cattgtcggt cataggattt ttattgattg ctgtggttat
     6661 cttatttttt atcaacggtt ataatctaaa aatgcgtgca gcttttgtga gtatactgat
     6721 ctttttattt tgtttcctac tattgcttcc tatcactgat tttttagcga tccaaggttt
     6781 tacatcggta gaactagaag aattatctgg cttagataag actttagcga ttgattttag
     6841 attacttacg agatcgttgc ttctgattag tcttagtggt gctgttttag atgctagtgt
     6901 agcaatttct agtgggacat tcgaagtata tcaggcaaat ccgcaattat ctttttacca
     6961 attgcgccat tctagtttcg ctattgctaa aaaaatattg gcgtcaacag taatgacact
     7021 tctttttgca ttcatgggaa gttctttagc gttgatcctc tggtttattg atttagacat
     7081 tccttttcag caagtgatca atgaaaaatc atttgttcta gaatatacga tggctattct
     7141 taccacattg tctgcactac ttgttcttcc tttaacctgc gtgactacag catatctctt
     7201 tacaaaaaag aaagaacaac tcaagatgga gtaaaagtta caacttaagt cctatgacat
     7261 ttttactgaa tcagtgcata atatggatgt aaggaaaagc ttgcaaacaa ttttgcttaa
     7321 ggaggcaatt tccatgaaag aaagagaacg tattttagat ttagtgaaaa aaggaatcct
     7381 ttcgactgaa gaaggcttag atttattaga aagcatggca actgaaaaag acgaaaagca
     7441 aataaaaaaa gaagcagaca aggtaactgc tagtcataaa gaaaaagatc aggcaagtca
     7501 attgatcgat aaacttgaaa acggcgaaga agaaatttct gagccagttg atccaaagga
     7561 aagagaaagg caagatcaag aaaacttaga aaagatctta gatgaactag caactgaagc
     7621 gaataaaact tcggcgcgtc tagatgaagt aaatgctcaa ttcgctgaca ataaggcagc
     7681 acgcaatgag aaacaggaag cattgatgca gctgaataca aaagaagaat taggcgagtt
     7741 gacagaagaa gaattagcac agcgtcagac gttagaagca gaaatcaaag aattagaagc
     7801 tagtggcgat acactgttag aagaacaatt gaaattagaa gcagaattaa aagatatccg
     7861 taagaatcaa tggtctgaga aaaaagaaac gtttactgat aagtttgaat tgccagatga
     7921 ttggaaagat caagcaacag atacactgaa tcaagtaggc gaaaaaatgt cagaagctgg
     7981 atcacagtta ggcaaattct tgaagaaaac attccaaact gtttcagaaa cagtgaatga
     8041 caacatggaa tggaaagatg tcagcttacg tgtccctggg attgcgacaa cgaaatttga
     8101 gcatgaattt tactatgaag ctcctgcagc aagtatcctt gatatcaagg cagcaaacgg
     8161 aaacgtgacg ttaaaaacgt gggacagcaa cgatgtgaaa gttgaagcta agatcaaact
     8221 ttacggaaaa atgggtgctg aaccatttga agcattctct gaacggagcc agattgaggt
     8281 taatgaagat catatctcct tccaaattcc aaataaacgt gtgcgtgcag accttgtttt
     8341 ctacttacct aaacgagtat acgaccacgc agctattaaa cttctaaatg gcaacatcat
     8401 gattgaaaca ttggaagcta aagatattta tacaaaatct acgaatggta acatcatcgt
     8461 ggaccaatta actgcaacga tgctggaagt agaaggtgta aacggcaata tcgatattcg
     8521 aaacgggaac atcttagatt ctattatcga aacagtaaat ggtacagtga catttggtgc
     8581 gacagcagaa aacctttctg tgtctttggt aaatggtgat gtacgtctta cgattaaaga
     8641 agataatttg aaaaaagtag aagcaagttc agtgaacgga aatgtcaaag tcgctttacc
     8701 agatggcatc ggtttggaag gacatgctaa aacaagtctt ggaagtatca acagccgtct
     8761 gtccaattac gaagtagttc gtgagaaaaa agaacggaca aaccaaatgt tgcaattccg
     8821 tcgtgtttca gatggtgaaa tcacgcaagt gcaactttca acgacaacag gaagtatcta
     8881 tttaaaagat acagataaat aaagaggttg tgaaagagat gttcagcctt gagcaataag
     8941 aagcgatttt gtaaaatagc ttcccctatt ttacaaaatt gtgccttatt gccgataggc
     9001 tatctcttga acaccgttta ccaagagatt atgaacctgc caattatcgc cgagtcacaa
     9061 ggaataattt cagaaaaagc tcgtcacgtt ttatgaatat ggtaatttgt gaccgagaat
     9121 tttgcagaaa gacaccgatt aagaagaagg ttgtcacaac gattttcttc atttaaaata
     9181 gtagaacaga ggtgagacat gatgaaaaaa aagttgacaa aatccaataa aaatgttgtt
     9241 ttgacaggga ctttagcagg aataggagaa tacatcggga ttgatccgac tgttatccgt
     9301 gtgctttatg tattcctgag cttagttgct tttggaagtc caatcatttt atacatttta
     9361 ttagctttga ttatcccatc tgcgcgttct gcacgaacaa actatggaca taacaatgca
     9421 tattatgaaa aaaacaatta tcgtgaacaa actcgtgaac aaacaaaaaa acgcaaagaa
     9481 gcggaaaaaa tcgatgatga cgaatggagt gacttttaat gtcgtacttt caacgtattt
     9541 tagttaatac gttaacattc atatcattgg ctgttctttt tcctgcgatg gtccatgtga
     9601 gcagtatttg gacggccgtt cttgccagct tcgtattgtc tgtgttgaat atgtttgtca
     9661 aaccgatttt gacgatactg tccctgccct ttacattagt cacattggga ttgtttacgt
     9721 ttgttatcaa tgcagcgatt cttaaaatga cctccttttt tgtgggagca gaacatttta
     9781 gtttttcttc attcggtgca gcgttgttag tagctatctt gatgtcgctt gtcaatgtaa
     9841 ttgtcagtga acataacagt agaaaataaa agaaagctgt gccgaactat cggcgcagtt
     9901 tttttattta gaatcaggaa tgcgttttct attacattgg taattaaata aaaacgtttt
     9961 ttttaattgg tagtactttt ggctagacaa tgataaaatg atagagaaca ctctaataga
    10021 aatgaggtag catgaatgtc agaagttgta aaagttagcc aattagtgaa aaaattatct
    10081 ttggaaatcg tgacaggcga cgagaaaagc ttagaccgtg tcatcgtaac tggggacatc
    10141 tcacgcccag gactagagtt gactggttat tttaattatt attcccataa tcgtttacag
    10201 ctatttggca gtaaagaaat cagttttgcg gaacggatga tcccagaaga gcgtttgatc
    10261 atcatgagaa gattatgtag tgaagatatg cccgcattta ttatttcaag aggattaccg
    10321 gctccagaag aaatgatcca ggcagcaaat gaaaatggga tagctgtact gcgttctccc
    10381 atctcaactt ctcgtttatt aggagaatta tccagttatt tagatggtcg ccttgcccct
    10441 cgaacaagtg tccacggtgt tttagtggat gtttacggat taggtgtact gattcaaggt
    10501 gacagtggga taggaaaaag tgaaacagcg ttggagttga tcaaacgcgg tcatcgattg
    10561 atcgcagacg atcgagtaga tgtttatcag caagatgaat taacggtgat cggagaaccg
    10621 cctaaaatcc tggaacatct aattgaaatc cgaggaatcg ggatcattga tgtaatgaat
    10681 ctttttggtg cgagtgcggt acgtggctct atgcaagtcc agttggctgt ttatctggaa
    10741 gcatgggcaa aagataagaa atacgaccgt ctgggctctg aagacacgac cgttgaaatc
    10801 gcggaagtgg gcattccaca aataaaaatc cctgtcaaaa caggacgaaa cgttgcaatc
    10861 atcattgaag tagccgcgat gaatttccgt gcacgtacaa tgggctttga cgcaacgaaa
    10921 acatttgaag aaagattaag tcgcttgatt gaagaaaact caggcaacga ctagcaagga
    10981 gtgacaatat gttagcacaa atcaatcgag ttgcttttga gcttgtaggg attcctatct
    11041 actggtatgc attgatcatc gtatcaggta tcattatcgc catgtggctt agcagcagag
    11101 aggctgttcg ggtaggatta aaagcagatg atgtgacaga ttttatgttg tggggattgc
    11161 ctatctccat tattggtgct cgcttatatt atgttttatt tgatcttccc cagtatatag
    11221 ctgatccaat ccaaatattc aatatccgtt caggaggctt agctatttat ggcggactga
    11281 ttgcaggcgc gatcacgctg tattttttta ctaaatatca ttttatttct ttgtggactt
    11341 ttttagatat cgctgcacca agtgtattat tagcacaggc aatcggtcgt tggggaaatt
    11401 tcatgaacca cgaagcatat ggaccagaca cgacgcgaag cttcttagaa agtctgcatt
    11461 taccgcaatt catcattgat aatatgtata tcgaagggat ctatcgtcaa ccaacatttc
    11521 tttatgaatc actttggagt ttgattggat ttattttgct tttgttttta cgaaagaaac
    11581 cacacctttt gaaaaaaggc gaagtccttt tatgttatct aatgtggtat agtttcgggc
    11641 gtttctttat tgaaggatta cgtacagaca gtctttactt tttaggtgtg atccgtattt
    11701 ctcaattatt atctgctgtg ttatttgtcg gtacattgat tctatttatt tggcgcagaa
    11761 aaaaaggaaa tttaccggat tatgaccgct cattaggaaa aaatcaacaa attatctgat
    11821 ttttagagcg ttaaaaatga aaaaaatttc aggagtggta aaatgaatta tagagtagcg
    11881 gttttaggac caggctcttg gggtactgct ttggcacaag tcctcgccga aaacggacat
    11941 gacgttcgga tttggggaca tcgtgcttca caagtagaag aaatcaacac ccaacacacg
    12001 aatcaacgtt atttaccaga tcattatcta cccgattcca tccaagcatt caccaatatg
    12061 gaagatgcag taaaagacgc agatgcggtg ctattcgtca ttccaacgaa agcaatacgt
    12121 tctgttgcaa aagaactagt gcctaaattg aatacaaagc cagtgatcat ccatgcaagt
    12181 aaaggattag aacagggaac acataaaagg atctctgaca tcttgttaga ggaaatccca
    12241 gcagaaaaaa gaaaagctgt tgttgttctt tctggaccaa gccatgcaga agaagtagcg
    12301 aaacatgaca tcactacgat cacagctgca agtacagatg caaaagcagc aaaatatgta
    12361 caagagctgt tcatgaataa ttattttcgg atctatacca atcctgatgt gatcggtgta
    12421 gagatggggg cagctttgaa aaatattatt gctattggtg ctggcgctat tcacggctta
    12481 gggtttggcg ataatgcaaa ggcagcaatc atgacgcgcg gattagctga gatcagccgt
    12541 ttaggtgtag caatgggtgc caacccgctg acctttatcg gattaagcgg agtaggcgat
    12601 ctagtcgtta cttgcacaag tgttcattct aggaactggc gcgcaggcaa cttgttagga
    12661 caagggcagc ccctagaaga ggtgctagcc aatatgggaa tggtcgttga aggtgtgaat
    12721 actactcaag cagcgatgga actagcccaa ataatggaaa tcgaaatgcc catcactcaa
    12781 acaatctatg aagtgctgta tgaacaaaaa gaaatcaaaa cagccgcaaa agaaatcatg
    12841 ttacgtgatg ggaaaaaaga aaatgaattc tcattaacaa ttttttgaag gagcgaatgt
    12901 atatgaaagt caaaaaagca gttattccag cggcaggatt aggaacaaga tttttaccag
    12961 caacaaaagc tatggcaaag gaaatgttgc caattgttga taaaccaaca atccagttca
    13021 tcgttgaaga agcgttgaaa tcaggaatcg aagacatctt gatcgttaca ggaaaagcta
    13081 aacgaccaat cgaagatcac tttgattcaa atattgaatt agaaacaaac ctaagtgaaa
    13141 aaggaaagac cgaattattg aaattagtag aagaaacgac agatgtcaac ttgcatttca
    13201 tccgtcaatc tcatccaaag ggtttaggac atgccgttct tcaagcaaga gcctttattg
    13261 gaaatgaacc gtttgtcgtt atgctaggcg atgatatcat ggaagatgaa gtaccattga
    13321 cacagcaatt aatcgatgat tacgaacgta ctcatgcttc tacgatcgcc gttatgcaag
    13381 ttcctcatga tgaaacttca aaatacggaa ttatcaatcc aggagaagta ttggaagatg
    13441 ggttatacaa tgtcaaaaac tttgttgaaa aaccagatcc aagcaaagca ccaagtgatt
    13501 tagctattat tggacgttac ttattgactc cagaaatttt tgatgtattg tccgagcaac
    13561 aaccaggagc cggaaatgaa atccaactaa ctgacgcaat cgatacattg aataaaacac
    13621 aacgcgtatt tgcccgtaaa ttcacaggta aacgttacga tgtcggtgac aaatttggtt
    13681 ttatgaaaac aagtattgaa tatggtctaa cacatccaga agtaggtgca cctttacgtg
    13741 agtatatcct gtctttaggt aaaaaattag aagcagaagg aagcaagatc gatcataatc
    13801 caaaaggaat aacagaaatc aaagaagaaa agaaaaaata accctttttt ctaacgagct
    13861 tcagctgcta attgaataaa aagtagttga agctcgtttt tatttgttta aaaaacacga
    13921 aaatgctatc cttatagaaa agagagacaa gaagggagtt tgatcatgtc aggaggagaa
    13981 attgcaggat tgatcgcagc aatcgccttt gcgatacttg tcgtttttat cgttcgtgtg
    14041 ttgttgcaag tttctaaaac tttagaaaaa gtagatcaga ctgtagcaga agcaaatacg
    14101 acgatcgaaa tcgtcacaaa agacgtagat cttttgtcta gacaagtaga aggcttgctg
    14161 gtcaaaagta atgaactgct cttggatatc aatggaaaag tcgcaacgat cgatccattg
    14221 ttcacagcag ttgctgattt aagtgaaagt gtatcagaac ttaatcattc tagtaaaaac
    14281 atcgcgacga aagtcggcgg aatcggtaaa acgacagcta aagcgacggt tgccggaaaa
    14341 gtcggtggga cagcgatgaa attttttaaa aacaaaaaac atactgaaac gacaggagga
    14401 aaataaaaat ggctaaaaaa ggtggatttt tattaggtgc agtagtcgga ggaacagccg
    14461 cagcaatcgc cgcgttattg ttagcaccaa aatctggtaa agaacttcgg gatgaattag
    14521 ctgcccaagc ggatgatttg atggatatgg cttcagatta cacagatatg gcgaaagaaa
    14581 aatcgactga gttaacaggt attgcaaaag aaaaagcgca agatctttct caacaagcag
    14641 gtgatctagc aggtagtgtc aaacaaaaag taagtgaatc agcagatgaa gcaggaagtg
    14701 aatctgacga tatcttgtta aatcttaaag aacaatcagc tgacttatct aatcgtttca
    14761 aaaaaacggc agaagatatg aaaaaacctg cagatgaatt aggaagtatt gctaaagata
    14821 cttcagaaga tatcatgatt gatgtaaaag acgctgctgg taaagcagga gatactgtca
    14881 atgaaggaat gtcagaagca aaaccagttg cagatgacac aaaagaaatg atgaaaatgg
    14941 caaaagaaga tgcgaaagaa gctaaaaaag aaataaaaga tacaatgaca gattcatcta
    15001 caaatcacta aaatcactaa aatcacaaat ttatagaata aaaaggtggg agcggactag
    15061 ctctcacctt ttttactctt atttttctaa aactagtaat tcttttggtg tagtcgtgaa
    15121 tggcacacag ccatcgcttg tcacatatac acagtcttcg atacgtaccc ctactttttc
    15181 aggaatatag attcctggtt caagagagaa gcacatccct tcttcgatta ctaagtcatt
    15241 tccttctaca agggaaggga attcgtggac ggttgttccg atcccgtgac ctaaacggtg
    15301 attgaaatat tcgccgtagc catagctgtt gatcacgttt cgtgcgattt gatcaagttc
    15361 acctgctgtc acacctggac ggacggcttc ttgtgcggca agctgtgctt caagagtgat
    15421 gttgtatatt ttttcttgga agtcggttgg tttttgataa gcaattgtac gagtagcatc
    15481 actgcaatag ccattccaaa caacgccaag atcgaataac acaagttcat tcggtgaaat
    15541 cttcgtgttt cctggtgtac catgagggct tgcagcattt gctcctgcaa ggactaatgt
    15601 gtcgaaagac atttgtgaaa caccttgttt tttcaattgg tattcgattt ctgcaatgat
    15661 cgcttgttca gtcacgcctt ctttcactgc tttaaagcca atctcaaatg caacatcggc
    15721 ccatttacca gcttcgatca gtttgtcttt ttcctctaga gttttgatca gttgtagacg
    15781 ttggatgatg gaagctagat cagtgtaaga atccgttccc gtcaagatat cagagatagc
    15841 atcgaagcgc tcgacagtca aggcgttctt ttcaatccct acattgccag gctgaccata
    15901 gcgagcacga agttcttttc cgatgatctc ccaagggttt tcgctgtcta aatagccacg
    15961 gacatcatac gcccaactac tgttttgagc atcttcaact tccaaagcag gagtgaaaag
    16021 gaaaggatct tgttcaagag ggataaaaag agctagtaca cgctcatgag gatcactttc
    16081 gtatccggaa aagtaagcga tgtggccagg gtcgctgata taagccaatt cgacttggtg
    16141 ttgtgccatc cattgacgta gttcattgat ttttacgtta ttcatttggc aacctacttt
    16201 ctaaattaat tttgtattca ataattgtac cactgattta ttaaaagacc aacgttctaa
    16261 aaactgaaaa aagtaaaaat tttcatgaaa acagagataa aacggttgca attcttgaga
    16321 ttatttgata ttctatttta gaaatgtaag acgtattttc agaaaacata taaaatatga
    16381 ataggagaac acaaatggaa aagcaaacaa tcactatcta tgatgtagcg agagaggcaa
    16441 atgtttcgat ggctactgtt tcacgtgtcg taaatggcaa tccaaacgtc aaaccagcaa
    16501 caagaaaaaa agtcttggaa gttatcgatc gcttggatta tcgtccaaac gcagttgcgc
    16561 gtggcttggc aagtaagaaa acaacaacag ttggggtaat catccctgat gtcagcaata
    16621 tgttctttgc ttctttagca cgtggtatcg atgatgtggc aacaatgtac aaatacaata
    16681 ttatcttagc aaattcagat ggtaacgacc aaaaagaagt caatgtattg aataacttac
    16741 tggctaagca agtggacggc gtgatcttca tgggtcacca tatcacagac gaaatccgtg
    16801 gagaattttc acgttcaaaa actcctgttg tattagctgg ctctattgat ccagatgaac
    16861 aagtaggtag cgtaaacatt gattatgtat cagcaacaaa agatgcagta aacaaattgg
    16921 caaaaagcgg caataaaaaa atcgcttttg tcagtggtgc gttgatcgat cctatcaatg
    16981 gacaaaatcg tctgaaaggc tataaagaag cattaagcga aaataaccta ccatatagcg
    17041 aaggattgat ctttgaagca caatacaact tcaaagatgg tctatctcta gtcgatcgga
    17101 tccataatag cggtgcaaca gctgtctatg tttcagatga tgaattagcc atcggtattt
    17161 tggatggttt attagaccgt ggcgtgaaag taccggaaga attcgaaatc atcacaagta
    17221 acaattcact actgacagaa gtagctcgtc ctcgtttaac aagtatcaca caaccattat
    17281 acgatttagg ggcggtatct atgcgcctat tgacgaaaat gatgaataaa gaagaagtcg
    17341 aagaaaaaac gattatcttg ccttatggaa tcgaagaaaa aggatctaca aaataataaa
    17401 aggacaacca ttcagaggtt gtgagcctgc cgtttaactc tgcgttacaa ggagcaattt
    17461 caaaaaacag catttcatgt ttgatgaata ttgtgactcg tgattcggag ttggcaggag
    17521 aacaccgttt attcgggaaa aggggttatg acaaaatttt gtttaatcct ttttttttgt
    17581 cttaaaaaag agagaaagtg gttgaaatta catttatcgt atataaaaca atccgtgtat
    17641 agatgctgca ttatgttcac caccatcaaa aaaataaggg actgtgtatt ctattaaatc
    17701 aatcatcttt ctcatctgat tctttggttg cttgattcgc tcttgcataa gctgaagcgg
    17761 tgttccagta atctgtatag ttttcatcgg taccgccaac gccaaattta aaggcgcttt
    17821 tcttcggtcc atttttcgcc catagcgatt caactgtttt tcctggtgtt tggatggatt
    17881 ttttattgac agtaactttt ccaggtgttt gaccagtaaa tccagatact tttttcttca
    17941 tcacatcaga tgataattcg aatttctcat cagtgccaaa aatgtcaggt tttgcttggt
    18001 aagcttgatt gatcagattg gcaagataat tagccgaacg tatccttgct ttgctgtcca
    18061 ttccagtatt gtcatcgtgc cctgcccagc tactgatggt aatagacgga gtagagacaa
    18121 ttagccatga atctcggtat tcattggtag aaccagtttt tccgacccaa tctgcttttc
    18181 ctagatttcc gtttaagctt gagatggcat ctttgaatgg tgtagtgatt tttgcattga
    18241 tcacactgcg catcatgtca ttcatgatcg atgccgttgc ttccgaatag atccggacag
    18301 agttgctttc gtgtttataa attacatttc ctgcgttatc tgtgatggaa tcgatgatat
    18361 agccttcttc atagacgccg ccgtttgcta aagcctgaaa tccattggtc tgttgaagcg
    18421 tcgtgacatc tactgtacct aaaggagcag attcaacgcc ccaattgtca tttgccgggt
    18481 agttcatctt tgccaagtag tgctcgtaag catattgttt cgatccaccg gaattcaaca
    18541 catcttgata taagtgataa gccgggatat tgttggacca ttctagtgac tcacggacgg
    18601 tttggaaggt gttcgatcct tcgttagtag cattgacgat tttctcgcca gcattttctc
    18661 cttcttgcca agttgttgca taatctgata cacgggattc tgatccgata agccccatgt
    18721 cgattgcagg tccataaaca agaactggtt tgattgatga gccagcttga cgttctgtat
    18781 cgaaggcatg gttattttga ttctgactgt aattccgtcc gccaacgaat ccgtagatgc
    18841 ggccagttct gttatccatc aatacatttc cggtttctac ttgactgcca gcaccatcat
    18901 ctaacatgta tccataattt tctacgccat tttgcaatgc agcatagaca tctttatcga
    18961 ttgtcgaatg gattgtatat cctttatttt ggatcgtttg ctgtgccttt tgataataag
    19021 cgtcactgac cgatgaatca gacatatcag cgttgtcttt ttcagccaat tgttgtgcaa
    19081 tgattcttgt tgcttcattc atcacagtat aatacaagaa ttctctgtca gtctgttctg
    19141 cgatttgttg tggtagaaag tcttttgtaa ggtcataggc ttttgcttct tcgtattgtt
    19201 ctttcgtaat ttggccttca cgatacatac tgaataaaac aaaatctttt ctggcaaggc
    19261 cggcagaaag atcttctttt agcgcacctg tgttcgtgta tggactatac gtgatcgggc
    19321 tttggggtaa tccagcgata taagcagctt gcggcagcgt cacatctttt gcatctacac
    19381 caaagattcc tcttgcagct tcctggactc cagcaatgtt ttgtccctta ttattacgac
    19441 caaatggtga gacattcaaa tacgtagcaa tgatctcatc ttttgaaaag tatttttcta
    19501 cttgtgcaga aagaatgatc tcgtttgctt tacgtttgaa tgttgtttca tctgtaagga
    19561 tctgctgttt gactaattgc tgtgtcaaag ttgatccacc agaagagcca ataccagtag
    19621 cttcagatac taatgctcgt aaaacagctt taggaacgta accttggtgt ttatcgaagt
    19681 attcatcctc tgtgctgata attgcagttt tcaataaagg tgaaatttta tcagatgaaa
    19741 tagtcgtgcg catcagatct gtctggattt ttgatatctc tgtattatct gcataaacaa
    19801 tctttgacgt ttctgtaatg tttcctagtt ctgtctgcag tgctttttta gtcggcaatt
    19861 gtgtgtcttc gacgagatag gcaaaatagc cagcgcctat tccaatacct agagctgcga
    19921 acatcaaaag aagaacagta ataaaaacag tcaatgattg aaaaactcta aaaataatct
    19981 taggaacaaa ccatttttct ttttttcttc tattctgttt ttttcgagta tttttgcgtg
    20041 gcaaaagggt cacctcaact aatggtttta tttcgctaat tatagcaaat aatagaacaa
    20101 aaaaacagac aaggctgttt ttggcaggaa tttctttttt aaaagagtta aaacgtgaga
    20161 aaatgatctt ttttataaaa gagttcttaa gcttttcttt agagaaaatt tcagttacta
    20221 tggagaacag ggcaaagaaa aatcaatcat tttctttgta tatcatctta ccaatatata
    20281 ggaattgtta gtaacaattg cctttcaagg aggaatccat ccatgttatt aggctcacac
    20341 gtcagcatga gcggaaagaa aatgctgtta ggagcagcag aagaagcagc cagttatgga
    20401 tcttcgactt ttatgatcta tacaggcgcc cctcaaaaca ctagaagaaa agccatcgaa
    20461 gagatgaata ttgatgccgg aaaagcgtac atggcagaaa acggtctaac aaatatcgtc
    20521 gttcatgccc cttatatcat taatttgggg aatacgatca aaccagaaat gtttcctttt
    20581 gccgtccaat ttctgagaga agagattgtt cgtgcggaag ctttaggcgc tactcaaatt
    20641 acacttcacc caggtgctca tgtaggggca ggaacagaag ccggaattgc tagaattatt
    20701 gaaggcttga atgaagtttt gacaaaagaa cagacggcac aaatcgcttt ggagacaatg
    20761 gcaggtaaag gtacggaaat cggtcgaaca tttgaggaat tagcgcaaat catcgatgga
    20821 gtaaaattga atgaaaaatt atccgttact tttgacacct gtcatacgaa tgatgccggt
    20881 tataatatta aagaagactt ttcaggtgta atggaagagt ttgataagat catcgggtta
    20941 gatcggctta aagtactcca tatcaatgat tctaaaaatc cgcaaggttc gcataaagac
    21001 cggcacgcca atattggttt tggaacaatc ggattcgaca cgctgaataa gatcgtccat
    21061 gatccaatgt ttgacaatat ttcgaaaatc ttggaaactc cctatgtcgg caaagataaa
    21121 aagaaagctt acgcaccata tggaaaagaa atcgccatgt tcaaagcaca aatattcgat
    21181 ccagaagtgt ttcctgagtt attagcagaa gaagtgatac tctaagattt tctatctgac
    21241 agcagcaaaa aaggaccagg cacattgcct tgtccttttt tgtttaagaa acaaaggagt
    21301 gctttttgca gtctttttca tcatgcatct tctcccccct ctttttaaat ttagacaaac
    21361 agggtatact ggtagaaaag taaaaaaacg aaaagtttca caagcaagtg gcaaaacgtg
    21421 attggaagga cgaaaagatg ctgaacactt taaaaccctt gatcaaccaa ctaaaaaaga
    21481 aacatacata ctttattctt ggcatagccc tattatttac aattattcgt ttgtatttat
    21541 atagtaaagc aatctatgga acagacatgt cggcaaccta tgatgaccag ctgctgattc
    21601 gctatgctca aaatattttg gacggtaaat ggctagggga gtatacgact acaacacttt
    21661 ccaaaggaat ctcctacagc ttatttttag tacttgcaca taaactgcat ctttcttatg
    21721 cagttttgtt cggcatgttc agtatttttg ccagtatatt ggttgcactc gcgtttaaac
    21781 cgatcgtgaa gaacaagtat cttcttttaa gtttctattt ttattttttg ttttctccga
    21841 ttagttttac acatgaatat tccactcgaa cgtatcgtaa tgccctcgtg attccggctg
    21901 ttgagatcat tatcgcttgt ttactagcta tttattaccg taaatatagt tccagcaaaa
    21961 aaatgctgcc gtggttttta gggctagctg tttcttttcc tttcttttgg ttcattcgcg
    22021 aagattccat ctggcttctt ccttttactg tagtcgcgtt aggcatcagt ttcgtccaga
    22081 tcttgctagg acaagacttt tctttcaaag aagcaaagaa gttaaaagaa cgaccatttc
    22141 tcctttcgaa acaagaatgg ctgaaacttt cattgttttt actccctcta gtcggtttct
    22201 ccatcgtcta tcagtggatc gaatataaaa acgagacaac atatagtatt gccgccatca
    22261 atgaccgttc gagtggcgaa tttggacgtt tgatgaaaca gctgatccga atagatgacg
    22321 aaacgaactt aaataaagaa aacagtgaga tatgggtctc gcatgctgca ttaaataaag
    22381 cattagacgc atctcctaca tttcatgctg tttctactcg tattgacgaa ttgtatacga
    22441 ctcatgcgtg gacccaaggt ggaaaagtaa aagaattacc aggagatatc attttttggg
    22501 cattgcgaga tgtggtaagc gaatctggtt attaccaaaa caatgcaaaa gaaaccaatg
    22561 atttttggaa aaaagtcaat caagaattag aagaagccta tcaaaaggga actatcaaaa
    22621 agaaaaaaga attctatctg atgggatcag gggatggaaa gacgatgaat gatctgccaa
    22681 tcgtatttgc ttttctgaaa tcaggatatg cctatgcatg gcgatacaaa gatttccatc
    22741 aaggggggaa ttatagtttc ggtacgcaag aacaagtcga acaggcccaa gaattattga
    22801 atcttccact aatggataat tggatcgata gcagtgatcc gagaacacct gatttccagt
    22861 tgacaaaaac agcaaaagtc gcgaatgtca tgataaaaat ttaccaagtt ctggccattc
    22921 ccgtgctgat tgcttcaata gcagggatat tacttatgat actaggaacc gcatttgcaa
    22981 aagctgatcg tgcctattat agttcctctt tgattgtagt caccggatta atactgacac
    23041 aattggtttt tcttttcggc gtctcgtggt tttgttctta tgcgccagaa aaaaaggatt
    23101 attttttaag tgtctacact ggcgcaggcg tgccattaac gcaattcatc gtagtaacaa
    23161 gcatgctagt tttcagtaaa ttgaatctga aaaaagcttt atcttccaaa taaaaacata
    23221 ctaagattag aggagaacat cattgacgaa tgatgttctc ctctattttc tatttttaga
    23281 ttatagtgaa gagtgaaaga aagttcgaac aaagccttga ggactatgag tccctatcaa
    23341 aaaccgaact tctttactgt cattttagaa tcaggtttac gtatgttggg gccatgagcc
    23401 cgtgtatagg aaattggaat cgaaatgaag cagtaaagtt ctttcaaaac ttaaaaagga
    23461 ggaaaacaaa tgccttacat tcttgcatta gatgtttcaa tgggacacag ctacagtgtc
    23521 ctatacaaag acgacacctg cttatttgaa gacgagatcg aacacactca aagaggattt
    23581 catgcattac tcgaagagat ccagcacttg cctgaacgtc cattgattgt ttttgaagca
    23641 acggggattt attccagacc agtcgaaaag ttctttcaag atcatcactt ttcttactgt
    23701 ttgttaaacc cgttagaagc gaaaaaacag atggaagaaa acaccttatg cagttggaaa
    23761 acagataaat cggatgccca tcggctcgca cagactcatc ttaaaaatca acgtcagcca
    23821 aaagaagtac aaagcaattt ttacttagag atgcgcgatt tagcccgttt ttatcaagaa
    23881 attgagaaga aaatcactcg tctgcgcatg gatttacaca actgccttca gttgactttt
    23941 ccagagcttg aacagttctt tttaaacagg ctgacccctt acgcattgat attgatccgt
    24001 ctttttcccc atccagattt tgtattggca tctactcgga caaaaataaa aaataaactg
    24061 atcaacgaaa cacggaaaaa aatctccgcg aatcgtgccg agcaaaaggc agatcaaatc
    24121 atccactatg cacagtgtgc ctatccagct gttgaaaaag acagtatcca ctgtcaaaaa
    24181 acgatctatt acgctgaact tctccaagat ttactcgaac aaaaagaagc actggcgaca
    24241 caaatgatca aaaaagccga aggctctcct tgctttttgt tgtaccaaac gttccctggg
    24301 attggcgcac tcacagccgc tttattgctc ggtgaattag gagatatcac acgatttaaa
    24361 acccataaac aattgaatgc ctttgtcgga atcgacatcc gacggtatca ttcaggtaag
    24421 tatactggcc aagaccgcat caataagcgt ggtaatccca aagcacggaa aattattttc
    24481 ttcaccattc gaaatatgat tcgccagcaa cgcgcagctc ctaatcatat tgtcgattat
    24541 tactacaaat taaaaaagca acctatccct aagaaagata aggttgccac agttgcttgt
    24601 atgaacaagc ttctgaaatg tatgcacgct atggttaggg cacatacaga gtacgactat
    24661 gcgtacgcgg tctcagtgga ccattaacta aaccacttac agtataccac ttctttgccc
    24721 agatcgaaaa ttttttacga acggggcttt atttggtgtg ccttgatttt gtcgctttcg
    24781 tttatgagct atttttctta caccttttac ttgactaatc gtaggaaagg gaactgtgac
    24841 aaaagtcttg tcgcagttcc tttttccgaa taaacggtgc tcaaaagctt gcatctgcgg
    24901 taataagtcc aaccaagtta aaaacataaa aagctgtttt tacttggctg ttcttattac
    24961 ttgatgcaag gcagcttttt cacaacctct gatacacggt gttccagaag taacttcttc
    25021 ggaaataagc cgaaatttca caaaaatttg aaaagcaatt ttcttaaatt ccttcttatt
    25081 tcttgaagct gcccacttct gacacaacct cctttgtgta aaagaatcag tttctactcg
    25141 atttcttcta tcgtttcctg caaacgctgt tcatattttt tgtttccttt atataaatca
    25201 ccaatcgtcc atgccaacag gagaaggaca agaacaatga ttacataagc gatttgatca
    25261 gccaatgcta gttgagctga ggtggcttgc tcgccgaaga aactttcgat ttgacctggt
    25321 aatcctcgta aattcaagta agtcagacta atcacagaga accagccaag tagttttaca
    25381 acaaatgaat ttttgaatcg gctccccatc tccgcttggc tattggtcat catcagtaaa
    25441 ggaatcatcg agaatggcaa tgcaaaagcc agaaaaactt gggattcatt catcaagtta
    25501 ttcaaagcgg tatgttcttc gatcgttcct tttgtacttg taaacaaaac acaaatcaat
    25561 acaggaatca cagaaagcaa tcgtgtgact agtcttctta gccaaattgg gatacgcata
    25621 tggatgaagc cttccatgat gacttgaccg gtcaacgtac cagtaatagt agagttctgg
    25681 ccagaagcaa gaagtgctac agcaaataaa gtagacaaga taccagattt tgctacagca
    25741 atcaagatac cattgctcat agctgatgga tcagataaag cttcatacag accaaaaaag
    25801 gaaggatctt ggacagaacc ggttttgaat acagccacac ccatgatcaa tagcagtgca
    25861 ttgactagaa aagccattga caactggata ttagaatccc aagtagaaaa gcgtaccgct
    25921 tgtgctacat cttcttcgtc ttggtgatcg atcttccgag tttgagaaac tgctgaatga
    25981 agatataagt tatgcggcat gactgttgca ccaataatcc ctaaagctcc agtcagcgga
    26041 gtttcgccgc cgatgaccgg tgagtctgag aatgtgtgac tgttagggat aaatccggca
    26101 aacaaactgt gccaatcagg gttagacaag ccaacttgat agacgaaaac gaataaaatg
    26161 acgaaaatca agcagacaac caaagcttcg attttacgaa acccgacttt tgtcagcaat
    26221 aaaaggacga aaacatctaa cacagtgata aatacggcaa ttaccaatgg aatatcaaaa
    26281 agcaggtaga gggcgattgc tgcaccaatg acttctgcga tgtctgttgc cataatggct
    26341 aattcagtca agatccataa aatgacaccc aatgtcttac ttgtccgtgc tcggattgct
    26401 tgggccaaat ccatttgggt cacgattcct aattttgctg ccatatattg taaaagcata
    26461 gcaatcagac tagacatcaa aataactgac atcaataaat attggaaatt ttgtccacca
    26521 gtgatcgaag tggaccagtt acctggatcc atataaccaa ctgctactaa tgcacctggt
    26581 ccagagtaag caagaagtgt tttaaaaaaa ctttttccct tgggtacatc cactgttcca
    26641 tttacttcag ctaaagataa accatttgta tgttcaataa gtcgatgctt atgaaattgt
    26701 ttgttggatt gattattcaa gaaaaaacca cctttcctat ttatctacga ttacattcta
    26761 cacctcagaa agaaaaaatt aaagaaaaag atttggtatg cctaattttt tttcgtggcg
    26821 tgtcttgctg gttaatgaaa gaaattttgt tcttctctaa aaaaaccact attttttgca
    26881 tgaaactaaa gaatacgcct ttcttttttc aataaacttt agtaaaataa atcattgaga
    26941 gcaattcgga aatagaaagg agagatttat atggtatcaa caggtattgt cgtacttatt
    27001 gctattattg ctttgctaat cggcgcagta ggtggctttt tcctagcgcg taaatatatg
    27061 aaagactatt tagaaaaaaa tcctcccgtt aatgaggaca tgttgcgatc aatgatgatg
    27121 tcaatggggc aaaaaccatc tgagaagaaa attcgccaga tgatgcagca aatgaagaac
    27181 caagggaaaa aataggttct gacccaaaga ctttttgcgg gctgattttt tcagtccgtt
    27241 ttttatttcg taatttgtta gactattcag actattcagc aaaaaagaca agcacagaca
    27301 atcctatgct cttgataaag acaaaggagg agtaaaatgt cgatttttag aaaattaggt
    27361 tggttttttc gacaggaaaa gaaacattat ttaattggga ttttctccct attcgcagtg
    27421 gccttggtac agttagctcc tccaaaagtg attgggatca tcattgatga gatcgccgat
    27481 aaaaatttat caataaagat catttcctgg tggatcttat tattgatcct tgcagctctc
    27541 ttacaatatc tttttcgtta tatctggcgg acgaatattt ggggaagtgc agctcggttg
    27601 gagaaagaac ttcggcagca gctattcaaa cattttacag aaatggacaa tctcttttac
    27661 caaaaatatc ggactggaga tttgatggct catgcaacga atgatttgaa tgcaatccaa
    27721 aatgtagcag gagctggtat cttgaccttt gcagattcag tgatcacggg cggaacaacg
    27781 atcattgcga tgattttgtt tattgattgg cgcttaacac tgattgcgct gattcctctg
    27841 cctttactag ccgttacttc acgagtgctg gggtcaaaac tccacgatgc ttttcgtgat
    27901 tcgcaagaag ctttttctag tatcaatgat aagacacaag aaagtattac tgggatcaaa
    27961 gtcattaaaa catttggaca agaaaaagaa gatctcgcgg attttgaaga aaagattgaa
    28021 gatgcaatta ttaaaaacaa acgagtcaat tttttagact ccttatttga tccattcatt
    28081 accttgatta tcggtctgtc ttatgttgca acaattattt taggtggaaa gtatgtcttg
    28141 gaaggcacga tctcaatcgg gcagatggtc tcatttatta gctatatcgg tatgcttgtt
    28201 tggccgatgt ttgcgattgg tcgattgttc aacgtattgg aaagaggaaa tgcttcttat
    28261 gatcgcgtca atgaactttt gcatgaaaag acgcatatcg tggaacaact gggtgcagtg
    28321 cagactccgg caaaaggcga gctgaatgta gctatttcct cttttaacta tccgaaagaa
    28381 gaatcaccag cattagaaca aatcaaattt gcgatccaag aaggagaaac attaggtatt
    28441 gttgggaaaa ctggtgcggg aaaaacgaca atcatcaaat tactgatgcg tgaatacgat
    28501 gattatcaag gaaaaattca atttggcgga tgttcgatca aagaatattc attgaatgct
    28561 ttattaggat caatcggcta tgtgcctcaa gatcacttct tgttttcgat gaccattcga
    28621 gataatatcc gtttttctaa tccaaaactt tcagaagaag aagtagagca tgcggcttct
    28681 ttagcattta tcaacaatga aatcaaggaa ttaccaaaag gttatgatac cttagttgga
    28741 gaacgtggag tctctttatc tggcggacag aaacaaagga tttcgattgc tcgagcattg
    28801 atcaaaaatc ctgaattgct gatcttagat gatgcacttt ctgcagtaga tgccaaaaca
    28861 gaagaagcta tcttgcataa tttaaaagaa ataagaaaag agaaaacaac catcattgca
    28921 gctcaccgtt taagcagcgt gatgcatgca aaagaaatca ttgttgtcga tcaagggaaa
    28981 atcattgaac gaggaaccca tcatgagctg cttgcattag gcggctggta tgaacgaatg
    29041 tgggagaaac agaaattaga agcgaagata gaaggaggcg aggcctgatg gatgaaaatt
    29101 atcaatcgga atggacaaaa tcgattccac ttaaagaaca gaagaagatc atcaaacgac
    29161 tgatgaagtt cgccaaacct tttagaagaa cgttcatcgt tgctatctta tttgcgtttg
    29221 ccctgtctgt gatcaatgtc ctattgccaa ggatcatcca aacttttatg gatgatcatc
    29281 tggctaaaca gtcggctacg acacaagtta ttttgttttt tgctggtatg tacttgtttg
    29341 gagtcatagt caaaagtatc atttggtttt tccaatggta tttgtattcc atggcttcat
    29401 tgaagaccta tcagtatgtt cgggtaagat tatttgaaaa gctgcataca ctaggtatgc
    29461 gttattttga tcagacaccg gcaggatcga ctgtttctcg agtgacaaat gacacagaaa
    29521 cgctatttga attttggtat gtctttttga tggtattgac tgggatcttt gcagtcgttt
    29581 cttccttcat tgccatgttt caaatcaatg gagaaattgc cttgtggact ttggtgttct
    29641 tgccgatttt aggaatcgtc atctggtatt accagaaatt cagttctcgt atttaccgga
    29701 atatgcggga aaaattaagt cagctgaaca cgaaattgaa tgaatcgatt tccggcatgc
    29761 gtattatcca gcagtttcgc caagaagctc gtttagctaa agaatttgaa caagtgaaca
    29821 acgagtattt agacacgcgc tatgcgatga tcaaaacaaa ttcgattctg ttaagtccga
    29881 tcatcaattt tctatatgca ttggcgattg cgttggcgtt gactttgttt gggatcgatg
    29941 cgctgcattc tcccgtagaa gttggactga tctatgcatt tacgacctat gtccagggat
    30001 tttttaatcc aatgtctcaa atgatggact ttttgagcac ctttacagat ggaatggttg
    30061 ccggtagtcg tattttgaaa atcatggata cagaagaata tgcaccgcaa caaaatcctg
    30121 gagcagatca agcgattact tcaggtaaga tcgagtttcg caatgtaagc ttttcttatg
    30181 atggagagca caatgtattg aacaatatct cttttgtcgc taatccggga gagaccgttg
    30241 cattagtggg gcacaccgga agcggaaaaa gctcgatcat caacgtattg atgcggtttt
    30301 acgaatttta tgaaggccag atcttgattg atgatcatga cattcgagaa tatccaatgg
    30361 aagagttacg taagaaaatg ggattggtct tgcaagatgc cttcttgttt tatggagata
    30421 tcgcaggaaa tatccggatg atgaatccaa ctatcacaga cgaacagatt cgccatgcag
    30481 ctgagtttgt tcaagcaaac aagttcatcg atgaattacc aaaaggatat cactcaaaag
    30541 tgatcgaaca cggtgccagc tattctagcg gacaacgaca gctgatcact tttgcgcgaa
    30601 caatcgtgac agatcctaaa atactagtat tggatgaagc gacagcaaat atcgatactg
    30661 aaacagaagg attgatccaa gaaggattga caaaaatgcg acaaggacgg acaacgattg
    30721 cgattgccca tcggctgtcc acgattcggg atgcagaatt gattttagtt ttagacaaag
    30781 gtcatatagt agaacgtggg aatcatgaaa cacttctagc gcaaaatggt ttgtatgcag
    30841 atatgtacaa actgcaaagc agtggtgtgt aaaaagtggt tgtgacaggg ctccgttcag
    30901 ctttaggtga taagaaaaaa attgtaaaaa aggctttcca gatttttgca taaatttggc
    30961 ttatcaccga taagctggta ctggaacacc gtatattaga agttgggaca gtagcatagt
    31021 agcattttga cctaagcgct agagtgaaaa taaaacagag cttcccagat tcttcatctg
    31081 tgagcgttag tgtcgtaatt accagattta aaaaaaatca cgacagctag tcagaagtgc
    31141 ccaatagccg ctaagaaagc gttgacaaaa gtgcttgctt tcgataatat aaagaaaacg
    31201 atacaacttg gatagtgatt gcctgatgca agctaaacct gatgagtctc ccatggttcc
    31261 atggacggct ttttgggttt ttctttttgt tttggataca gccctatata tcatggaaag
    31321 gagtaaaaca tgctgattga gaaagtactg aataacaacg tcgtaataac cagggatgaa
    31381 agaaatcagg aaatgatcgt gatgggaaaa ggtttggcat tcaaaaagaa agtgggtgac
    31441 ccgatttttg actcatgcat cgacaaaaaa tttcagttga caaatgacgg actttcacaa
    31501 cagttccaag aattggcaca agcgattcct cttgagtact tagaaatttc ttgtgaaatc
    31561 attgaatata caaaagaggc tctacaagtc cagttgaatg attcggtgta tattgcattg
    31621 acggatcatt tgtatacggc tatcgaacgt cacaaaatgg gaatatttgt accaaatgta
    31681 ttgctgtatg atatcaaaca actatttcct aaagagtatg ccatcgggaa aaaaacagtg
    31741 aagaaaatct cggataaata ccacatcaag ttatcagaag atgaagccgg atttatcgca
    31801 ttgcatttag tcaatgcaca aggcattcaa agccaacaag acaataccta cctgtttact
    31861 acaacaatac aggatattct aaatatcgtc cgctattact ataagattac atttgatgaa
    31921 gattcagtcc atttttttcg attcgtcaca cacctacgtt tttttctgac acgcgtccta
    31981 gatggagaaa aatcagaagt gggagaagtt tctgaggaat tgtaccaggt tattcaaaaa
    32041 aaatataagg atacgtttgg ttgcgttgag aaaatagcag actttttagc cgagatattc
    32101 aactaccaga tgtccacgga cgaaaaaatg tatttaacga tccatattgc gcgtttagtg
    32161 catgagaatc gttgtaaata aataaaaaaa ggaggataaa ttaacaagaa cgcatgaaat
    32221 aagggtagtg acattcagtt ggctaaacct tccactaata aattggaggg aatagaaatg
    32281 ggaaaatatc aagaattagc gagcaaaatt gtagaaaatg tcggcgggaa ggaaaatatc
    32341 aatggtttga cacattgtat cacaaggctt cgtttcaaat taaaaaacga agaaaaagca
    32401 aatgatgaga tcttgaaaaa tatggacggt gttgtgacgg taatgcgagc gggaggacag
    32461 taccaagttg tcatcgggaa tcatgtgcca gtcgtgtttg aagaggttat aaaagcagga
    32521 aaccttactt ttgatgaggc tgtttcaaca gaaaaaatga gaccgtttga tatgcttatt
    32581 gatggaatat cgggctgttt ccagccattc cttgctattc tagctgctgg tgggatgatt
    32641 cgtggactga cagcattact tgtcttctta ggcgcatttg accgcggttc tggcacattt
    32701 gttatgtttg ataatatcgg tgattctgta ttccaattta tgcctgttat tatcggttta
    32761 acagctgccc gtaaatttaa agtaaatgaa ttcgtaggga tgttgcttgg ggcagcatta
    32821 atgaatccta gcttgtcgct ggaagctttg agtggtgcag cagaagcacc actgactacc
    32881 atattttctg gcactatttt tgaagcacct atttatcaaa cagtattcgg cattccctgg
    32941 attgcgcgta actacgcttc ttctgtcatt cccattatct ttattgtgtt gttagctagc
    33001 caaattcaga aaccaattaa aaagttagta cctgagatga tcgcgaattt cttcgttcca
    33061 ttcttcaccg ttcttattac aatgccctta ggttttttac tcgttggacc agcattcaca
    33121 ttcgcaactg atattttaat ggctggattt gaaacacttt tagcactttc gccagttatt
    33181 tatggagcaa tcgtaggctt cttctggcaa attctagtga tgtttggtct ccattgggca
    33241 atcgtaccaa tgggattgat gcaattttct gtgaatggtt ggcaaaatat catgacacct
    33301 gttgcagtag tgtcttttgg acaaactgca gcacttactg cactctactt taagcttaga
    33361 aacccaaaag acaaagcaat cgcaatacca gccattgttt ctggtattgt ggggattaca
    33421 gagccagcta tttatgggtt tacattgcca cgtaaaaaaa tatttatttt tacctgtgtc
    33481 ggtggtgcgt tagggggcgc gtatagtgga ttaatgaatt taacttcttg gaatccaggt
    33541 ggattaggca tctttacaat tcccaactat attagaccag atggtgattt aacggatgtg
    33601 attaatgtat tgattggaat cgccattgcg atggtggtat cctttgcgct gacttttttc
    33661 ttttggaagg aggaagcagg tgaaacagat gatagacaga aaagatcagg taaagaaatt
    33721 gtaaaaacac cgatacaagg acaaatcgct ccactgaatg cagcaaagga tgcagctttt
    33781 gcacaaggaa cactaggtcg aggaatcttg atctaccctg aaaaaggaga agtacgtgcc
    33841 ccttttgacg gaacagtcat gaccctgttc ccgacgaaac atgcaatcgg aatggtttct
    33901 gaagcaggtc tggaattgct gattcatgtc ggattggata ctgttcagtt ggaagggaaa
    33961 tattttgaaa gcttggtgca gcaaggagaa agagtgaaac aaggcgatct gttgctccgc
    34021 ttcgacaaaa agaaaatcga agaggaagga tacagtttag aaacacctgt gatcgtcacc
    34081 aattacacgg attatttgga tattttggaa aatcaagggg agacggtcgg gccagacgat
    34141 gcacttatca ccgcactgac ctgaacggtt aggtgaaaga atggactagg cttaattatt
    34201 ctttttagtc cacttcttta ttttcaaaat tgaaaggctc tttcatgatg gctgagctga
    34261 tagggcgttt atcaaatttt tgtcctacag aaattagatg gactaaattc tgttgataat
    34321 tttctgcaaa aacacaacta tataacacgt ctagaagata acaaatcgat gtattgatcg
    34381 taaaattacc aattttcgaa tacagtcgtt cgcgtgtcgt aagtcgcaaa gcggctgtac
    34441 tcattgaaga tagcgttgaa tcaccgatac tggtcaaagc taaaattgga acatgatttt
    34501 gtttcaatat ttctgcggta cgaaggatca cattgttttc acccgtataa gaaatcagaa
    34561 tcccgcacat atcactcgtg caattgtacg cttcatagaa cgattcacca aaagtggtga
    34621 caatcgtgac atccattttg atgcgcttca ttttcagcat gaaatcttga gaaatcaaag
    34681 tattcgagtt actggcgaaa atcacgattt tttttgcttg aagcattagt tgtttggctt
    34741 tttgcagttg gtcatgatga atgagagaaa gtgtatcttg aatcgtcatc tgttctaaag
    34801 aagccatttt atttgcgatc gtcataatac cgtctgtggt ggaaaaagga agattcgcat
    34861 ctacgtcttg aaaattccct tcaagatagg ctgtttcagc taaaaaagca ttacgaaaac
    34921 tgacccagcc atcaaaaccc attttttttg ctacacggat gagtgtggac gggtggacat
    34981 aacatcgctc agcaatctct tggatggtca tttcgccaag tgctggagaa tcgcttaaga
    35041 gaaactgaat cacttcattt tctgaaggag aaaaggagat ttctttgatt ttttcacgta
    35101 ataacatgta gataccttct tcttgttttt ttacgtaaat tataactttt ttgaaaatga
    35161 tttgtaaacg gatttatgtt atatagctta ataaagacat tttttgacaa gatatttaca
    35221 aaaatccagt agaaaacact aacttttgta aatgttactg gaaagaaacg aatttctatt
    35281 gtttgttttg tttacaaaaa agataataaa agtgtaaaaa gtaaaggagt gagaacatgg
    35341 caaaaggaat caaaatcgct acgattggtg gaggcagcag ttacaccccc gagttgatgg
    35401 aaggatttat caaaagatat gaggaattac cgatacgaga aatctggctc gtagatgtag
    35461 aagaaggaaa agaaaagctt gagatcgtca gtcagatgtc tcagcgtatg tgggatgctt
    35521 ctccgtatga agtcaaaatc tatgcaactc tggatcggga agaagcattg aaagatgcgg
    35581 attttgttac gactcagttt cgtgtcggtc aattagatgc acgaatcaaa gacgagcgga
    35641 tccctagtta ttatgggatg attgggcaag aaacaaatgg tgctggcggg atattcaaag
    35701 cttttcgtac cgttccagtg gttttggcaa tcgttgaaga catgaagcgt ttatgtccaa
    35761 atgcttggct gatcaatttc gcgaacccaa gcgggatggt gacagaagca gttatcagat
    35821 atggcaaatg ggataaagtg ataggattat gcaatgtgcc agtaatggcg atgatgacag
    35881 aaccaacaat gcttggcaag aaaaaagaag agctgatcta caagtttgcc ggtctaaatc
    35941 acttccattg gcacaaagta gcagataata aaggaaatga ccgcacggca gaattgattg
    36001 atcgtttata cgatgaagac aatggattgc cgaaaaatat ctttgatatc ccgtttttca
    36061 aagaacaatt aaaacaaatg aacatgatcc cttgtggcta ccaccgctat tactaccgtg
    36121 aagaagaaat gctggaacat gctttagaag aatatcaaac gattggtaca agagcgcagc
    36181 aagtgaaaga aacagaagca gagctgtttg aattatacaa agatccagaa ttggatcata
    36241 aacctgaaca attgcaaaaa cgaggtggtg cttattattc agatgctgcc tgtgaaacga
    36301 ttgcttcgat ctatggaaat aaagaaacac agatcgtggt atctacaaag aatgatggag
    36361 ctgttcctga tctgccggca gattgtgtag tagaagtcac tgcctatgtt ggcgcacaag
    36421 gcgcacgaaa tgtagcgttt ggttcccttc ctgctgctga aagaggctgg ttgcaagtaa
    36481 tgaagaatat ggaattgctg acgatcgaag cagctgtgac tggtgattat ggaacagctt
    36541 tacaagcgtt tacgatcaat ccgcttatac gatcaggaaa gacagcaaaa cggatcatga
    36601 atgagttgtt tattgcacat cagcagtatt taccgcaatt caaggaaaca atcagccggt
    36661 taaaagcaga aggaatcgaa gtccaagatg aactggcaag agaattatca agcaatacac
    36721 atgtaatgga ggaagtatga tgggattcag aaaagatttt ttatggggcg gagctacagc
    36781 agccaatcaa tgcgagggcg gttatgatga aggcggacgt gggttagcga acgtagatgt
    36841 tgtgccaatc ggagaagacc gttttcctgt cattactgga aaaaagaaaa tgtttgaatt
    36901 tgatgaaaat catttttatc cagcaaaaat tgcgatcgat atgtatcatc attataagga
    36961 agatattgct ttatttgcag aaatggggtt caagacttat cggatgtcca ttgcttggag
    37021 tcgtattttt ccaatgggcg atgaaaaaga gccaaatgaa tctggtttga aattttatga
    37081 ggatgtcttt aaagaatgtc aaaagtacgg gatcgagccg cttgtgacga ttacacattt
    37141 tgattgtccg atgcatttga tcaaagaata tggtgcgtgg cgttccagag aactcgttgg
    37201 tttttatgaa aatctgtgcc gagtcatctt caatcgctat aaaggacttg tcaaatattg
    37261 gttgacattc aatgagatca atatgatcct tcatgcacca ttcatgggcg cagggctgta
    37321 ttttgaagaa ggagaaaatg aagaacaaat caaatatcaa gcggcacatc atgagttggt
    37381 tgcaagtgcc atcgcaacga agattgctca tgaagtagat ccggagaaca aagtaggctg
    37441 tatgctggca gcaggagcat attatccata cacttgcaat cctgaagatg tttgggcttc
    37501 tagaaaatca gatcgagaaa attatttctt cattgatgtc cagtcacgag gagaatatcc
    37561 tgcttatgca ttgaaagaaa tggaacgaaa tggcattcag atcaaaatgg aacctgggga
    37621 tgccgcattg ctgaaagaac atactgttga ttttatctcc ttttcttatt attcttctcg
    37681 agtttcgact actgacaacg aactcttgga acagactgca ggaaatatct ttgcttctgt
    37741 caaaaatcca tatctggaag caagtgaatg gggttggcaa attgatccat taggcttgag
    37801 aataacgatg aatgatattt atgatcgtta tcaaaaacca ctatttattg tagaaaacgg
    37861 cttaggtgca gtcgatacgc ccgatgagaa tggttatgtg gaagatgact atcgaatcga
    37921 ctatctggca gcacatatcc aggcaatgaa agatgcagta gaattagatg gagtcgatct
    37981 attaggctat acgacttggg gatgtattga tttagtatca gctggtacag gtgagatgaa
    38041 gaaaaggtac ggattcattt atgtcgatcg tgacaacgaa ggaaatggca cattagcccg
    38101 ttcgaagaag aaatcattca actggtataa aaaagtaatt gattcaaatg gagaaaatct
    38161 ttcgaatgat tgatcaatga tttataaaag tctattgttt ttcagcggat ttttcgagta
    38221 taataaagct attcgagaaa cgcaagcaga acaatagact ttttttcgca ttggctgtaa
    38281 agtatgctta cttgattaag taaaggagaa tctacatatg tatgatgtaa tcgttattgg
    38341 cgcaggtcct gctgggatga ctgctgcttt atatgcttca cgttcaaact tatccgtatt
    38401 gatgatcgaa caaggcgccc ctggcggcca aatgaacaat acggcagaaa tcgaaaacta
    38461 tcctggtttc gattcaataa tgggtcctga tctagcttat aagatgtatg aaggtgtttc
    38521 aagatttggg acagaaaatg cttatggaat cgtgcaagat atcaaggatc acggcagcca
    38581 caaagaagtt atttgtgaag ataaaactta cgaaggaaaa acagtcatta tcgcaacagg
    38641 ctgtatccac cgtaaattag gcgtacctgg cgaggaagaa tttgctggac gtggcgtttc
    38701 ttactgtgca gtttgtgatg gtgcgttttt ccgtaacaaa cgtctagtag tgatcggagg
    38761 aggagactca gcagtagaag aagccatcta tttgacacaa tttgcttctg aagtagtcat
    38821 cgtccaccgt agagatgaat tacgtgcaca aaagatcatc caagaccgtg catttgcgaa
    38881 tgaaaaaatt tcctttatgt gggatacagt cgttgacgaa atcgttggga atgaaatggt
    38941 agtgacaggt gtgaaagcac gtaatgtcaa aaccggcaat gagtttgatt tggcagcaga
    39001 cggagtattc atctatgttg gactggatcc attaactgca ccatttagag aagcagggtt
    39061 gacgaacgaa gctggctgga ttccaacaga caacgaaatg aagacgaata taccaggcgt
    39121 ttttgccatc ggagatgttc gtgaaaaaga tttgcgacaa atcactactg ctgttggtga
    39181 tggtgggatc gctggacaac aagtgtataa atacttggaa tctttagaag aaacaactgc
    39241 ataagtttaa aaagagtgga agaacggttt aattgttctt ttactctttt ttttcgcgtg
    39301 aaatctactg aatccgattt atgcgaatac ttgcaaccgt gcttgataaa agaatccttt
    39361 cttgatttaa gcgttttttg gtcctcatac tttcatatct aataagtgaa tgctatactt
    39421 attaagaacc atatttcaga aagaggtgtt attttcatgt cttgggaaca agtgtatgaa
    39481 caatgggtac atgaagaaaa tttagaagaa aacttaaaaa aacaattaaa tgatctgggt
    39541 gaagatcctg aaaaacttga agatgctttt tatgcaccgt tggaattcgg tactgcaggc
    39601 atgcggggaa tcttagggcc tgggatcaat cgaatgaaca tctatacggt aagacaagca
    39661 acagaaggac ttgcacgttt catggataca caaggcgaag aaacaaaacg ccgaggtgtc
    39721 gctatcgctt atgactcacg ccatcaatca ccagaatttg ccatggaagc agccaaaaca
    39781 ttagcacatc acaatatccc atcttatgta ttcgaaagtc tacgtccaac accagagctt
    39841 tcttttgcag tccgtcattt gaagacgttt gcgggaatca tggtaaccgc atcccacaat
    39901 ccagcagctt acaacggata taaagtctac ggagaagatg ggggacaaat gcctcctgca
    39961 gacgcagatg cattgacgaa atatgtccgt gaagtcagca atccgttaaa agttgaagta
    40021 ttatctgacg aagaagctga acatagcgga ttgatcacga tcatcggaga agaagtggat
    40081 gccgcttatc tagaagaaat caaagcagta acgattgatc atgaattggt ggaaacaatg
    40141 gggaaagatt tgaaacttgt gtacacacca cttcacggaa caggaaaaat gttgggcgaa
    40201 cgtgcgttga aacaagctgg attcgaacaa ttcgtactag ttccagaaca agctgtcgca
    40261 gacccagatt tcactacagt caaatcacca aatccagaag aacactctgc ttttgagtat
    40321 gcgatacgac ttggcgagaa agaaggcgct gatttgctga ttgcaacaga tcctgatgca
    40381 gaccgtttag gtgcagccgt tcgtttgcca aatggctcct atgaagtatt gaccggaaac
    40441 caaatcggag cactgtttgc tcaatatatt ttggaagcac accaatcgcg aggcacttta
    40501 cctgaaaacg cagcggtatt gaaatcgatc gtttctagcg aattacctac agcaattgcg
    40561 gaacactatg gggctaccat gttcaatgta ttgacaggat tcaaattcat tgctgaaaaa
    40621 attcaacaat ttgaagaaga tcattcccat acttttatgt tcggattcga agaaagttac
    40681 ggttatttag ttaaaccttt cgttcgcgac aaagacgcga tccaagcatt gctcttatta
    40741 gcagaagtag cagcttacta taaaaaacaa ggcaaaacgt tgtatgatgg cttgcaaacg
    40801 atttttgaaa cctatggcta ctacgcagaa aaaacgattt ctgtgacaat gagcggacaa
    40861 gaaggttctg cgaaaatctc tgctttgatg gaaaaattcc gtgaagaagc accaacagaa
    40921 tttgccggag caaaagtcat ccaaacagaa gacttcaaag agttgacgag aacagaccgt
    40981 gaaggaaacg tagaaaaact aacgacaccg ccatctgacg tattgaagta tacgctggaa
    41041 gaaaatggct ggatcgctat ccgtccttca ggaactgagc cgaaaatcaa attttatatc
    41101 ggtgtaaaag gaaactcttc agaagacgca gctgaaaaag tagccgctta tgaaacgatt
    41161 atccaaaaga tgacagaaga ataaaaaaac ttgagactga tggaaaaagt ggtaaacttt
    41221 agaagtcagt cttttttcaa gttggaggtg aatggattgc cagacacgca aaaaacaaaa
    41281 gtagagaaag tcagccaact attcaaaatg ttgagtgacc ccactcgtct caaaattctg
    41341 ctgtatctga aagacgggga acaaaatgtg acagcaatca tccaagcagt ggaaatggaa
    41401 caatctgctg tatcgcatca actgcgttta ttaagagaaa accatgtcgt caagtcccat
    41461 cgtgagggaa aagcgatttt gtatagtctt gatgattctc acgtactgga tattttgaac
    41521 cagacactca aacatgtgga acatcaataa cgataggtgc aaatagagac aaactggact
    41581 gtgtcaacga atcttcttcg ctgacacagt ccagtttttt taaagaaaaa ttgttagtct
    41641 gtttcttcgg tggtttcagt tccataataa ctatggtctt ctaggtctaa agcattcaaa
    41701 ataagcgaag ctgtttcttc aatagataaa gaagcgacat tgattactac gcagcccaat
    41761 ttttcataaa gatcattcgc aaaatcgagt tcagctcgta ttttttcgat atcggaataa
    41821 gcagtatcag gatttaatcc gtaagagcgc atccgttctt tacggatatt gtttaaaata
    41881 tctgggttat tcgtcagtcc cacgattttt ttaggatcga tctcccaaag ctgtttggga
    41941 atatgtgctt gtgggatcaa aggtagattg gcaactttta aatttttgtt agctaaaaac
    42001 aagctcaaag gcgttttgga agttcgggat acgcctagca aaacgacatc tgcttctaga
    42061 aacccacgag gatctttccc gtcatcgtat tttacagcaa attccattgc tttgatccgt
    42121 ttgaaatagt tctcattcaa taaatgaagg gcgccaggtt gccgaatggg cttgatacca
    42181 gttaagcgct cgatttctga tatcggcgga gtcatcacat caaaactaaa taattgatgt
    42241 tcttcacaaa aagaacgcgt catctcgatc aattcttgat tgatcaatgt gtgcaggaca
    42301 agagcttttt cttctagtgc atcttgcagt gcctgcatca atgttttctc atctgtcaca
    42361 aatgttctgc ggaataaatt gaactcaacg ctaggatatt gggccatagt ggcttgcgct
    42421 agttttgtcg cagtttctcc agcagagtcg gagatgacaa aaaaagtaac gatttctgta
    42481 gaatcggaag acatggataa aacctcactt gcattttttt tatgtttatt ataccatact
    42541 ctagaatgtg tacttcgtaa tcattttgat ttggaggaat aagtcatgaa aaaacagacg
    42601 ttgatcgaac aatcactaga aacattgaaa aataacggtt ttaaatatac taaaaaaaga
    42661 gaagcattgt taacttattt agtgaagcgc aatcgctacg tatccgctaa agaagttttt
    42721 gactatatga atcaggaatt caaaggagta agttacgata cgatttatcg aaatctccat
    42781 gattttgcag aaatcgattt actggaagaa accgatttaa atggagagat gaagtttcgt
    42841 tttcattgct gtcaagggga aatcggccat caccatcact ttatctgtac ggtgtgcgga
    42901 acaacgaaag aaatccatat gtgtccaatg aattatttcg aagaacagct cggtggatgt
    42961 acgatcgaag ggcatagatt cgagattttc ggaagatgtg aaaattgtca ataaggattt
    43021 aaataaaata acatttgata attttaaaaa aaagcaagat ttccttgacg gtcaaaacag
    43081 cattagatat aatatttaca ggacagtctt gttttttgag atatatttca ataacaatta
    43141 cggttacttt ttaagctcgg agggagggaa ttaacatgtc aaaaacagtc gttcgcaaaa
    43201 acgaatcact tgacgatgct cttcgtcgct tcaaacgttc cgtgtcaaaa gcgggtactt
    43261 tacaagaatc tcgtaaacgt gaattctacg aaaaaccaag tgtaagacgc aagaaaaaat
    43321 ctgaagcagc tagaaaacgc aaaaaattct agttctgtga tgaattggag ttggtagtgt
    43381 gtcactacta agtagattaa acgatgacat gaaaacagcg atgaaagcga aagataagga
    43441 atctttacaa gtcatccgaa tgatcaagtc atctatacaa aacgagcaga ttaaagaagg
    43501 tcacgacttg acagaagaag aagaattaac ggtgttgtct cgcgaaatga aacagcgacg
    43561 tgattctttg catgagtttg aagaagcagg acgtgacgat ttagctgaaa aagtaaaaag
    43621 tgaaattgtg atagtcgaaa aatacatgcc ggaacaactt tccgacgaag aaattcgaca
    43681 acttgttcaa gaagcaatca cgcaaactgg tgcttcatca atgaaagaat ttggcaaagt
    43741 catgggtgcg atcatgccta aagtcaaagg aaaagcagat ggaaaccaag taaatgccat
    43801 tgtgaaagaa ctattacaat cttaatttta tcatttaaac tgcggacaat cattgtccgc
    43861 agtttttttg tgctcgtaaa aaagagatct aaaaaatagc tagacgaaag aataggattc
    43921 tttcatctag ctgttttttt cctgtttaat atttcttatg ttaaattgtg tttgatctgg
    43981 ttattcttct ggtagttcat ttgcttcttg tttataccct gataggcgat aggcgtaata
    44041 gaagagtaag ctgccagcat acccaagtaa cgttgggacc atccagccaa gtcccaatgc
    44101 agcaaaagga acgtgatgat gataaaattc gagcatgctt gctacaactc tttgttgact
    44161 cactaaagca ggcgaatttg ccagcatatc caatacggcg ggaacagcag caaacaacat
    44221 cgttacttga tagacaaatg gtgtcttttg gaaaaatttt gctgttaagg aaagcaaaat
    44281 caacgcaagc gacaatggat acaaaagcat caatactggt aaagaccatt ggatgatatt
    44341 gtccaaacca gcatttgcaa cgacaaaaga gacgaaagtc gttaaccgca gccatgtcat
    44401 ataactgact ttagggaaca gtttatggaa atcttgtgca aaagaaacaa cgagtcccat
    44461 agcggtagtg aagacaccta atgtgaccat cactcctaag aagctagcgc cgaagttacc
    44521 taaataaaaa ttagtgatct gagaaagtgc agttccgcca ttttctgata aagacatctt
    44581 attcaaactc atcgcaccga gaagaacaag accaaaatag atcatgactt ctagcgcaac
    44641 gctcaggcta ccagcttttg ctgttaattc tgtgactttt ttatctttga aaccaaggtc
    44701 acggactgca tggacaaaag tgacacttaa ggcaagcaag gctactgcat caaccgtgtt
    44761 ataaccttct aggacaccat ttgttaaagc gtttgtttgg taagtatctg cagcagattg
    44821 atttagattt cccattgggt ggaataaaga aacgacaaaa atgattgcta ataatgcaag
    44881 aaacaaggag tttagatact ttccgacgta tttgaccaac cgtgtgggat ggacagtaag
    44941 gaaataagca agtaaaaaga aaagagcaga gaataaaaac atacctaatg aattatattt
    45001 ttcaggcaaa aatggtttag cagccatttc aaaagcagta gcagctgtcc gtggtgtacc
    45061 gaaaaatggt ccgatcgtca aatgaacaag gattaagaac aaggcagcat accattttcc
    45121 gacaggttta gctaagtcat acagaccatc actttttgtc actactacag ctaagatagc
    45181 tagtaatggg aaaagagcgc ctgagatggc aaatcctacg ccagcactga cccagtttgc
    45241 gccagccatt tgacctaagt ggacaggaaa gattagatta cctgacccga aaaacatccc
    45301 gaagataagt gaactgacca tcaatagttg tttccatgaa taagtttttg tttcttccat
    45361 aaatttttcc tccaataatt atcattttga ttgacgatat aaacgttgca gcaattagta
    45421 atgccactaa tatcagattc catgaaaacc accaccttaa aatataaaaa aaagcccttt
    45481 tccacttggg aaaagggctc tagattctag aacggtacca ccttttttcg cttaaaaaag
    45541 cttcttcatt cacggacgct ttttgataaa gttatccgct agcctgataa tggaggcagc
    45601 cacaatgatc tacgttttcg acattgactc ggaaatgatg ttcgtctatt cgatttattg
    45661 tcatttctca cttacatgac tcactgggaa taaatcgttg aatagcctac tgttttcctc
    45721 gacgctttgc tgtatgttta tttgttgacg taataataca cctgtttttt ttgaaatgca
    45781 agaatatttt aactattttg ttttcttttt ttgaaacaag aaaaatacct agagaatacc
    45841 tctgaatgaa acggaatatt ttgttctcca ctttcatata acttacattc tcagattctt
    45901 tttatcaaaa cgagaccttt agcgaatgga aacagctatt ttttaacgtt tcttggtacg
    45961 tatggttaaa cgactctttt acaacctttt cttatttgct atatagtttc ttctgagtat
    46021 ggtaaaatag gaaagaatga atcgaaaaaa aggggatgtc tatttttgac ggaagagtct
    46081 agttctttag agattagatt gacagctgct gatgatgtca gcatgctttt aggtgcacac
    46141 gacaagcata taaaactgat cgaggaaaca acggaaacaa ccatccatac acgtggagaa
    46201 atcattcaga tcattggtga acaatcccag atttccttgg ctgcctcagt cattcggaca
    46261 ttacaggaat tgatcaaacg aggaatccac gtaagtacac cagatgtcgt gacggcattg
    46321 aaaatggggc aaaaaggtac attagattat tttgttgaga tgtatgagga agagatcgtc
    46381 aaagaccgta atggaaaacc tatacgggta aaaaacagcg gtcaaaagaa atacgttgaa
    46441 tcggtagcca aacatgacat cgtatttggt gtagggccag ccggaacagg gaaaacgttt
    46501 cttgccgtag tattagcaat tgctgcccta aaaaaaggcg aagtgcaaaa aatcattttg
    46561 acgcggcccg ctgtagaggc aggggaaaac ctaggctttc tacccgggga tctgaaagaa
    46621 aaagtggatc cttatctgcg gcctgtttat gatgctttat accaaatttt tggattggat
    46681 catacgaacc gattgatgga acgaggcgta atcgaaatcg caccattagc ttacatgcgg
    46741 gggcggacat tggatgatgc attcgttatc ttggacgaag cacaaaacac gacagtcgct
    46801 cagatgaaaa tgttcttgac ccgtctcggt tatcaatcaa aaatgattgt caatggggat
    46861 acaagtcaga tagacttgcc tcgagggacg acaagtggtc ttgttcatgc agaacgaaca
    46921 ctaaagcaaa tcaaaaaaat cgattttgtt aattttgaag caagtgacgt tgttcggcac
    46981 cctgtagttg ccgaaatcat caaagcttat gaaaaggcgg atcttcatca agaataagct
    47041 ttgcttagga ggataagcac atgttgaata aaacactgca gaaactacaa gaaaaactcg
    47101 gaaaggcagc attgcctttc cttctgttct tgttttttat cattgtctgc ggcgttacat
    47161 ttagtagtgt caaacaaaag gccaatgatt tcagagaagg ccaagtagca gaagagagta
    47221 tccgtgcgaa taaaacgatc gagaacacgg aagaaaccga acaaagaaga aaactggcag
    47281 cagaagcagt gactccagaa tatacttatc aaaaagatct ggcagatgac cagaacaatc
    47341 ggatcaagca attattcgaa ttgatcgata agacgaatga taccatcaac aaatcttata
    47401 atgacaaggt agataaggcg aaggaagatg aaaatatccc gaaacctact acagaagagc
    47461 ggattgctac actgaagaaa aattttgaaa acgtgaatgc agaaaacgtt gcgttttacc
    47521 aaaaactgcc gaacaatttt tattcgacga tatttgaaat gactgaaacg gaaattcaca
    47581 cggttaggga tgaaagtttg aagctcattg acgaacagat gagtaaacaa gttcgtgaaa
    47641 gcgaattgga agcttttaaa caagaagcag aagatcagat tcagtatttg aatgtcacaa
    47701 cagagcagca acaaatgatt cgctacttag tggatcaagg cattgtagtc aatgatgtat
    47761 tgaatgagaa aaagacagaa gaattaaaac aatctgcacg agaagctgta caaccagtga
    47821 tgatcttcca aggagaaatc attgttcgcg aaggaaatca aattgatgct tcagcgatga
    47881 aaaaattgga attactagga ttgacgaatc aaacgacttc gattttccca ctcattgcca
    47941 tggttttagc tgttttgctt caaatcggcg tactgattta taattcactt caattccaaa
    48001 atgcaggaga aagaacaaaa tacgtgcttt tctatgtgac agctatgtca gtcagcatag
    48061 tgctgatgaa atttttccaa ttattccaaa cggaacaagc tacttatatc ccgctgtttt
    48121 atcccgctgc ttttgcacca cttgttttaa gctttttctt gaaccgaaga gcagggatca
    48181 tggctggtat tttccaagca gtatctgcac ttttcatttt ttatgattcg attggcacga
    48241 actttctaac gattatcttg atgtcttatg ttttctctgg gctcatggca acgattgtca
    48301 gacgcaaacg gatctcagaa caaggattat ctgctgccat gtgggtcatt atttttcctg
    48361 tgatgatgga tgtcattttg atcgtctatc aaggaatgag ctttggtgat gcaacgactt
    48421 ggttaatgct tgtctgcggg ttcactggtg cactcttctc attcttgctg acgatcggtc
    48481 tacacccata tattgaattg atggtcaatg atgacagtgt aattgtatta aatgaactca
    48541 gcaatccaaa tcatccttta ttgaaacagt tgctggaaga agcgccaggt acttatcatc
    48601 atagtatgat ggtagctaat ctaagtgcta acgctgtagc agaaatcggc ggacgttctt
    48661 tgctaactcg agtagcttgc tattatcatg atatcggcaa gatcaaacat gctagctttt
    48721 tcgttgagaa cttgccttca ggagcggaaa acccgcacaa tttcttattg ccagaagaca
    48781 gtaaacatat tatctttgga catgtgacag atggagccaa aatattggaa gattataata
    48841 tgccgcaaat ggtgatcgat atttgcaaac agcatcatgg aaccacgcta atgcgttatt
    48901 tctacatcaa agcgaaagaa cgcaatccgg aagtaacaga agagcaattc cgttatcctg
    48961 gaccaaaacc gcaaagtcgt gaagcaggga tcgtcaatat tgctgacagt tgtgaggctg
    49021 cagtacgggc aatggatcat ccgacgagcg aaaaaatcga aagttttgtc cataatctta
    49081 tcgaagagcg tatttccgat ggtcaattag acgatagtgg actgaccttg aaagaaatcc
    49141 gaaaagtgga aaaatcattg atcagcggtt taagtagcac cttccattct cggatcaaat
    49201 atcctaaaat gaaaacagaa gttgagaaga taaaggaaga acaagaagaa tagaaagaag
    49261 cgatgtataa tggatattac ctttatggat gaaacaaacc aagtctcaga agagaaaatg
    49321 aaagaaatcg atgacttgct gcaatttgca gcatcttatt taaagctgcc agaggaaaca
    49381 gaaatgtctg ttactttcat ggacaatgcg gcaatccaag taatcaatcg tgattaccgt
    49441 ggaaaagatg caccgacaga cgtcatcagt tttgctctgg aagaagaagg cgaagacgaa
    49501 atcccagtga tttttgaaga tggagagaat cctttgcctc gtgtactagg agacatcatg
    49561 atttctattg aacgtgctgc tgaacaagca gaagcttacg gccattcata tgatcgggaa
    49621 cttggctttt tagcggtaca tggattcttg catatcaacg ggtatgacca tatgacacca
    49681 gaagatgaga aagaaatgtt tggtttacag aaagagatct tggatgccta tggactcaaa
    49741 agataaaaac gtagagaaaa acaaacattt cctgatgtct gtggaatttg ctgtccaagg
    49801 agtcaaaacc gtttttgagg aagaacgcaa tatgaggaaa catgttgcgt tcggtatcct
    49861 tgctttattt atgggcgtga ttttccagct tgatcggata gagtggttat ggctgctttt
    49921 agctgttttt ctcgtttgga tagtagagat catcaatact gtttttgaaa atgtagtgga
    49981 catgtttacg gattttcatt ttcatccgat tgggaaaaaa atcaaagata tggcagctgg
    50041 agcagtttta gtgaccgctt gttttgctgt catcattggg ttgattttat ttgtccctaa
    50101 aatatatcat ttgttgttta attaaaaagg agaacgtata tgccagaaca taaatcaggg
    50161 tttgtcgcaa tcgtcggccg cccgaatgta ggaaaatcca cattattgaa ccgaatcgtg
    50221 ggtcaaaaaa ttgccattat gagtgacaag gcacagacaa ctagaaataa aatccaagga
    50281 gtatatacta caccagaagc tcagctgatt tttatcgata caccaggaat ccataaacca
    50341 aagcatcgtc taggagattt tatggtagaa gcagcttaca gtgcgttgaa agaagtggat
    50401 gcagtcttat ttatgatcag tgctgatcaa aaacgcggcc ggggagacga ttttattatt
    50461 gaacgtctaa aaaacgtgca ttctccagtt tatctgatta tcaataaaat cgataagatc
    50521 catccagacg agttgctggg aatcatcgaa gattattcga cgcagatgcc ttttgcacaa
    50581 gtgattccga tctctgctac agaaggaaac aatgtcgaac gcttaatgga tgtattagtc
    50641 agtgaaatgc cagagggccc acaatatttt ccagatgatc aagtgactga tcatcctgaa
    50701 tactttatcg tttctgaatt gatccgtgag aaagtcttgt ttttaacacg agacgaagtg
    50761 cctcattctg tcgcagtcgt tgttgattcg atgaagcgaa acgagaatga taaaatccat
    50821 atccaggcca cgatcatcgt cgaaagagat agccaaaaag gaatcattat cggcaaaggc
    50881 ggaaaaatgc tgaagcaagt aggaacgaaa gcaagaaagg atatcgaaaa tcttttagga
    50941 gacaaagtat ttctagaact ttgggtcaaa gtccaaaaag actggcgaga caaaaaagtc
    51001 tatctgcaag actttggcta ccgaaaagac gaatactgat attctgaact tcttataggt
    51061 taagtataga aataaactgg ataaaaatcc gcacgttgag aaaaacggcg gaagatcgaa
    51121 acataaataa tctggatcgg cagaatctgc ttttccagat ttatttttta ggagggagaa
    51181 tatgagccag cttgcagaat cgaaaggctt gattttatct agccgtaatt acaaagaaaa
    51241 agataaatta gtcaaaatct ttacggaatc ttctggcaaa atgatgtttt atatcaaagg
    51301 aatccatcgg caaaatcagc cattagctcc ggctttgctc ccctttaccg aagcagtcta
    51361 tatcggtaat tttcgaagtg aaggtttgtc gtttttaagc agtgtcaaag acgtccatgc
    51421 gtttcggaac atccaagaag atatcttttt gagcggttat ggtacctatt tgctaaatct
    51481 agtagatgca gcaatcgaag atcatcaata tgacccgcat ttattccaat ttacgcaaca
    51541 agctctgcag cggatggatc aaggagatga tgcagaaatc atcacgaata tctttgaagt
    51601 tcaaatactg caacgcttcg gaatcgcgcc aatttggacg cactgtgtcg tatgcgggga
    51661 aacaaaagga aaatttgact attcttccaa atctggcggt gtgatatgcg agaaacactg
    51721 gccaatggac gaacaccgtt atcatgcaga tcctcgcgct gtttatttcg ttcgaatgtt
    51781 ttcggctatt tcttatgata agatcagtgg aatccacttg aaagaagaaa cgaagcaggc
    51841 aatccgtgac ctcattgacc agttgtatga tgaatatgtc ggtattcatc taaaaagcaa
    51901 aaagttcatt gatcaaatga agtcttgggc acacgtatta aagacgccag agaaaaatat
    51961 gcctgaaaaa gagatacctg aaaaagaaga ataaatgaaa gatacaacaa aaaaatcaaa
    52021 actatttgac aaatacaggg acttccgtct attattaacc gtagattaaa tagatcgttc
    52081 actgagagga tctattatat aaacaagaaa actgcaaaat gaatacgtac attgaccaag
    52141 atcagtaaaa aacacgtggt ttagcgagtt cgggagagtg gaagccggac ccaaacgatt
    52201 tttgaagagg cacttgcgag tacgataaat gaagctgccg aatctttatt cggaagtagg
    52261 gtggaaccgc gaaattattc gtccctatgt ctgtaatcag acatagggac tttttgtcgt
    52321 tttctttcct gtattcttat tgacagcaac gcttaaaaat tgaaaggggc aaaacagatg
    52381 agtaaaaaat tgaccgtcca agatatgatt ttaacattac aaaaattttg gtcatcaaac
    52441 ggctgcatgc tgatgcaagc ttatgacaca gaaaaaggag caggtacgat gagcccatat
    52501 acattcttac gggcaatcgg accggaacca tggaatgctg cttatgtaga gccatcccgc
    52561 cgaccagctg acgggcgtta tggagaaaac ccaaaccgtt tgtatcagca tcatcaattt
    52621 caagtcgtaa tgaaaccttc acctgaaaat atccaagagc tttatttaga aagcttgcgt
    52681 cttttaggaa ttgatccatt agaacacgat attcgttttg ttgaagacaa ctgggagaac
    52741 ccatcgatgg ggtgtgccgg tgtgggttgg gaagtatggc ttgatgggat ggagatcaca
    52801 caattcacgt acttccagca agtcggagga ctaccttgta aaccagttac ttctgagatc
    52861 acttatggac tagaacgtct tgcttcatat attcaagaag ttgaaagtgt ctatgatctg
    52921 gaatgggctg atggtgtgaa atatggcgag atcttcaaac aaccagaata tgaacattcc
    52981 aaatattctt ttgaagtaag tgaccaagac ttgctactaa gcaactttga ccgttttgaa
    53041 aaagaagcta aacgctgtat cgatgaaaat cttgttcatc cagcgtatga ttatattttg
    53101 aaatgcagcc atacattcaa tttattagat gctcgcggtg cagtatccgt aacagaacga
    53161 gcaggttatc tttcccgtat ccgcaacatg gctcgtgctg tagccaaaat ctttgtggca
    53221 gaacgcgaaa aattaggatt ccctttattg aataaaaaca cagcaaatcc agaaaacatg
    53281 aaggaggctg aataagatgg caaaagactt attacttgaa atcgggctgg aagaaatgcc
    53341 tgctcatgtt gtcacaccaa gcatgaaaca attagaagaa aaaacagcaa aatttttaga
    53401 tgaaaaccaa ttgacttatg atacgatcga aacgttttct acaccgcgcc gcttagcaat
    53461 caaagtaaca aacattccag aacgtcaagc agacagcgaa gaagaagtca aaggaccagc
    53521 caaaaaaatt gctttggacg cagatggaaa ctggacgaaa gcagctgaag gatttgtccg
    53581 cggacaaggt ctgacgacag atgctatcac ttttagagaa ttaaaaggcg tggaatatgt
    53641 ctatgtaacg aaatacactc acggcaaaga agcaaaagaa gtattgacag gtttagcaga
    53701 tgtcattaaa agcctcactt tcccagtaac gatgcactgg gcagaatacg attttgaata
    53761 tattcgccct attcactgga tcgtggcatt gttagatgac gaaataatcc cgtttgagat
    53821 cttggatgtc aaaacagaca gagcttcaag aggtcatcgt ttcttaggcg aagatgtgac
    53881 atttacgcat gcaaaagaat acgaagaaaa attgaatgaa caatttgtta ttgcttcacc
    53941 gcaaaaaaga aaagaaatga tcatcacaca agcaaacgaa ttagccgaaa aaaatcactg
    54001 gatcattgat ctagatgaag atttactaga agaagtcaac aatttagtcg aatatccaac
    54061 tgtcttttct ggcgacttcg aagaaaaata tctatctgtt cctgaagaag tactagtcac
    54121 ttctatgaaa gaacatcaac gttatttcga agtacggaac gatcaaggta tgttgcttcc
    54181 tcattttatt tctgctcgta atggcgatcg ggtaaaattg gaaaatgtgg tacgaggcaa
    54241 tcaaaaagta ttgacggctc gtttagaaga tgcggaattc ttttataatg aagacaagaa
    54301 agcttcaatc gaccaatacg ttgaaaaatt aaaaactgtt actttccatg aaaaaatcgg
    54361 tagcatctat gagaaaatgc aacgggtaca agtcatcgct cgcatcatag gcgaacaagt
    54421 aggactatct gaggaagaat tgatggatct gcaacgcgct gctgaaatct ataaatttga
    54481 tctagtaacc aacatggtag gagaattccc tgaactacaa gggatcatgg gagaaaaata
    54541 tgctctgctg aaaggcgaga aaccagccgt agcaacagcg atccgtgaac attacatgcc
    54601 tatatccagt gaaggagatt tacctgagac tacagtaggt tctgttttag cgattgctga
    54661 taaattagat agtatctttt ctttctttgc agttgggatg atcccaagtg gctcaaacga
    54721 tccatatgct ttgcgccgtc aagcatatgg tgtcgttcga atcatcgaat cgaaaaaatg
    54781 ggcctttcct ttgtctgttc tgcaagaaac gattagtgaa gttatcagta aagatacgga
    54841 tcgttttggc attggcttgt cagcgggaca acaacaggtg atcgacttta tcaaaggccg
    54901 tctgcgccaa ttattgacaa cgaagaatat ccgtcatgat gtcatcgaag ctgttttgaa
    54961 tgcagaacaa aaagatctga caaaagtatt tgcagcagca caattgttca agcagcatct
    55021 tgcagatgaa gacttcaaac catcgatgga agctttgaca cgtgtcgtga acttagcgaa
    55081 aaaagcggag cttgaaaaac aatcagaagt agaccctgaa ctgttcgaaa acgaagcgga
    55141 gaaagaactg cacaaagcag tagaggcaat gaaaacaagc tttgctgacc aaacgatcaa
    55201 cgaaaattat gatcagcttg taagccttcg cccactgatc gaaaattatt ttgatcagac
    55261 gatggtcatg gcagaagaac cagcagtacg taagaaccga ttaacgcaat taagtcaaat
    55321 tgctgccatg gctttgtcac tagcaagttt agatcaaatc atcacaaaat aatttctaat
    55381 atgtaaataa accagagaac aggcacaaaa taggctattt ctctggttta tttgttataa
    55441 atataaataa ctattattaa ttcaatgtta atttttttgt tattttattt tttgtgtaac
    55501 ttttaaaaac acctatgaaa attaaggaaa taaaaatgaa atcgattaat tgttatctta
    55561 ttaatgtttt atttactttt aaatcgtaaa ttgccctagt caagaaaa
//
LOCUS       DADVXE010000014        51254 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.014, whole genome shotgun sequence.
ACCESSION   DADVXE010000014 DADVXE010000000
VERSION     DADVXE010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 51254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.014"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(53..1558)
                     /locus_tag="KB913_000882"
     CDS             complement(53..1558)
                     /locus_tag="KB913_000882"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBB6819264.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(1650..2240)
                     /locus_tag="KB913_000883"
     CDS             complement(1650..2240)
                     /locus_tag="KB913_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6819265.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            2419..4065
                     /locus_tag="KB913_000884"
     CDS             2419..4065
                     /locus_tag="KB913_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6819266.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            4114..4833
                     /locus_tag="KB913_000885"
     CDS             4114..4833
                     /locus_tag="KB913_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBB6819267.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            5312..6259
                     /locus_tag="KB913_000886"
     CDS             5312..6259
                     /locus_tag="KB913_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6819268.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            6271..7191
                     /locus_tag="KB913_000887"
     CDS             6271..7191
                     /locus_tag="KB913_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6819269.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            7232..8689
                     /locus_tag="KB913_000888"
     CDS             7232..8689
                     /locus_tag="KB913_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6819270.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            9034..9648
                     /locus_tag="KB913_000889"
     CDS             9034..9648
                     /locus_tag="KB913_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6819271.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            9641..11365
                     /locus_tag="KB913_000890"
     CDS             9641..11365
                     /locus_tag="KB913_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6819272.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            11362..12813
                     /locus_tag="KB913_000891"
     CDS             11362..12813
                     /locus_tag="KB913_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6819273.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(13286..15439)
                     /locus_tag="KB913_000892"
     CDS             complement(13286..15439)
                     /locus_tag="KB913_000892"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBB6819274.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(15441..16487)
                     /locus_tag="KB913_000893"
     CDS             complement(15441..16487)
                     /locus_tag="KB913_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6819275.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            16637..17926
                     /locus_tag="KB913_000894"
     CDS             16637..17926
                     /locus_tag="KB913_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBB6819276.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            17939..20641
                     /locus_tag="KB913_000895"
     CDS             17939..20641
                     /locus_tag="KB913_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBB6819277.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            20626..21483
                     /locus_tag="KB913_000896"
     CDS             20626..21483
                     /locus_tag="KB913_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6819278.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(21554..22453)
                     /locus_tag="KB913_000897"
     CDS             complement(21554..22453)
                     /locus_tag="KB913_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6819279.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            22622..24793
                     /locus_tag="KB913_000898"
     CDS             22622..24793
                     /locus_tag="KB913_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBB6819280.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            24861..25202
                     /locus_tag="KB913_000899"
     CDS             24861..25202
                     /locus_tag="KB913_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6819281.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(25478..27232)
                     /locus_tag="KB913_000900"
     CDS             complement(25478..27232)
                     /locus_tag="KB913_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6819282.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(27243..28079)
                     /locus_tag="KB913_000901"
     CDS             complement(27243..28079)
                     /locus_tag="KB913_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBB6819283.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(28081..28764)
                     /locus_tag="KB913_000902"
     CDS             complement(28081..28764)
                     /locus_tag="KB913_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBB6819284.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            complement(28923..30317)
                     /gene="uxaC"
                     /locus_tag="KB913_000903"
     CDS             complement(28923..30317)
                     /gene="uxaC"
                     /locus_tag="KB913_000903"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBB6819285.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            complement(30356..31855)
                     /locus_tag="KB913_000904"
     CDS             complement(30356..31855)
                     /locus_tag="KB913_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBB6819286.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            complement(31848..33269)
                     /locus_tag="KB913_000905"
     CDS             complement(31848..33269)
                     /locus_tag="KB913_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBB6819287.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            complement(33329..34321)
                     /locus_tag="KB913_000906"
     CDS             complement(33329..34321)
                     /locus_tag="KB913_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6819288.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            34553..36751
                     /locus_tag="KB913_000907"
     CDS             34553..36751
                     /locus_tag="KB913_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6819289.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            complement(37209..38081)
                     /locus_tag="KB913_000908"
     CDS             complement(37209..38081)
                     /locus_tag="KB913_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6819290.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            38381..39355
                     /locus_tag="KB913_000909"
     CDS             38381..39355
                     /locus_tag="KB913_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6819291.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            39377..40069
                     /locus_tag="KB913_000910"
     CDS             39377..40069
                     /locus_tag="KB913_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6819292.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            40035..41543
                     /locus_tag="KB913_000911"
     CDS             40035..41543
                     /locus_tag="KB913_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6819293.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            41617..42720
                     /locus_tag="KB913_000912"
     CDS             41617..42720
                     /locus_tag="KB913_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6819294.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            42723..44060
                     /locus_tag="KB913_000913"
     CDS             42723..44060
                     /locus_tag="KB913_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBB6819295.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            44047..44925
                     /locus_tag="KB913_000914"
     CDS             44047..44925
                     /locus_tag="KB913_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBB6819296.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            44922..45845
                     /locus_tag="KB913_000915"
     CDS             44922..45845
                     /locus_tag="KB913_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBB6819297.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            45842..46252
                     /locus_tag="KB913_000916"
     CDS             45842..46252
                     /locus_tag="KB913_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBB6819298.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            46256..47824
                     /locus_tag="KB913_000917"
     CDS             46256..47824
                     /locus_tag="KB913_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBB6819299.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            48064..49482
                     /locus_tag="KB913_000918"
     CDS             48064..49482
                     /locus_tag="KB913_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6819300.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            49494..50804
                     /locus_tag="KB913_000919"
     CDS             49494..50804
                     /locus_tag="KB913_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBB6819301.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
BASE COUNT        16515 a         9054 c        10466 g        15219 t
ORIGIN      
        1 tcacagtccc tttttttctt agaaatggga aaccactagt atataaatac cattattctt
       61 caatcaaccg cttcacgatt gcataatccc cttcataagg ttcatctaca ccattgattt
      121 tttgataggg atccacgcct tttcccgcaa taacgactga atcttgcgga gcgctttctg
      181 ctaaagcgcg tcgaatcgct tcaggacgat ccatttcata atgaacgatc aaatctggat
      241 tagtaattgc ttcattgatt tcttccgcga tttttttcgg atcttcaaat gctgggtcat
      301 ctgccgtcaa aaaggcgatg tcagctgttt ctgatagcac ttttccaaaa tcatgtcgac
      361 gggagattgc tttgtttcct gggctgccta atacaacaat tacacggcca tctggatgtt
      421 catttttggc aaattccagc aatgttttca agcttagata attatgtgca tagtccacat
      481 agacatgcgc tccattggat tggatcaatt gatccattcg gcctggtaca cgagcttctt
      541 ttaatccgtc ttgtgcatct tgactggagg cacctgttag tgctgcggca atgatcgcac
      601 tggctgcatt ttcttggttg aatcctccag ccagcaaaat atcataagca gtatcgcaga
      661 tagctaagcg atcttcatga gaagataaag taaaaccgtg agtaccttta tctgaacgga
      721 tcacttgata attgctttct tccgaacgac cataagtgat cgttggaatc tggaatagat
      781 cggctgtttc cctaagtaaa tcaaaatagt cactttcatg atttaaaaca actgtttttg
      841 aattcaagat caattgtcgc ttgcaataga aatagtcatc aaatgtcgga tgttcgatcg
      901 gactgatatg gtcaggcgag atattcaaga agattccgac atctaaagtc aagccgtata
      961 cgcgttgtgt tttgtaagct tgtgaagaaa cttccatcac tagatgagtc ataccatttt
     1021 caactgcttc tgacatcata cgatataaat ctaatgactc aggcgttgtc aaatgggatt
     1081 tgaaatatgt tttgccatct aacgttgtat tcatagtaga aagcaatgct gtttttttat
     1141 ttgttgtgtg atccaagatt gcttttgtaa agtacgcagc agttgtttta ccttttgttc
     1201 cagtgaatcc gatcactttc aatttatttt gcggatagtc gtaaaaagcc atagcaagaa
     1261 gcgccattgc tttacggata tccgttacga tgattcctac tgctgaattt tcgtatggtt
     1321 gttctgatac ataatattga ataccctgtt cgattgctga atccaaatat tcttctttga
     1381 aattcattcc tttacagaaa aacaaagtag aagcatcagc ttttcttgaa tcataactta
     1441 actgaagaaa ttcagctttt tctggtacat caagatgcca gcctcttgtt gaaacaaatt
     1501 cttttaatag attttctttt aatagtaaat gacggatgtc ttctaaagag aagctcattg
     1561 attgatccct cgctttattc aatttcttgg tttattatag cacactcttt ttaatatatc
     1621 gtttgtttcc gctatgacaa aatccagctt tattcaaatt ttcttgacac aggggacaag
     1681 cggatgagta ttttcataaa caatgaactg actgtaatag ataggagaac gaatagtgtc
     1741 tccaacaatc caaaaacata ataattcaaa aagacgataa gactattggt aagtaaaagt
     1801 ccttgcggca ttggaagccg aaaaaatttg tggaaaataa tcggcggtat cgttataccg
     1861 ccatttgagg ccccgactgt gtacaatgtg taaaccccaa gactgaacaa aagacttcct
     1921 gaaatcagtg aaaagaaatg tgaggagatc atttccactt ttggaacaat ctctaaaaca
     1981 acaggaaaaa gcagacttcc cgctacagtc ttaaaaaata ctgattttcc taataggaca
     2041 gcggctagaa gcagcatcat aagattgatg ctccaaacag taactgagcg ttggatagaa
     2101 aaggccgttt caactaaatg tccgatggcg cccactccgg cggaagctat atcgtgaggg
     2161 agcaagaacc aattcaatcc aactgtgata aagaaaagac ctaaaaatat aacgggtagt
     2221 ttttttattt cttgtgtcat tgatatctcc tataaatgtt agccataaaa ggctgtatat
     2281 ttctttactt taccaaaaaa acgaaaccga attcaaaaaa acaattgttc ttataaaagt
     2341 tatataaaat cgattgccag tttctgtttt accaattaaa atgatagtaa tgttttgtag
     2401 aaagttggaa tctgaccgat ggataatcaa agaaaaccag cattagatca attaacaccg
     2461 caagaaaaaa tggcacgagg ctctgcttgg atgaccgcca gtaatatcat ttcaagattg
     2521 ctaggcgctg tctatatcat tccctggtat gcttggatgg gcgaaaatgc taaggctgcc
     2581 aatggattat tcaatatggg atacaatata tatgcattgt ttctactgat ctctacagca
     2641 ggaatacctg ctgcgattgc aaaacaaact gcacgctata attcattgaa tgaatatggc
     2701 acttcacgac gattatttat ccgtgcatta cagatgatgg gcgggctagg cctgttgttt
     2761 gctttgttca tgtacatcgc ctctccttgg ctagctcatg cttctggtgg cggagaagaa
     2821 ctgattccaa cgatgcgttc tttgagtatc gctgtattgg tttttccttg tatgagtgtg
     2881 atacgagggt attttcaagg caatcaagaa atgatgcctt atgcgctgtc gcagattgta
     2941 gaacaggtgg cacgtatttt ttatatgcta ttggctacat tcatcatcat gaaagtcatg
     3001 gatggtgact atgtgacggc ggtcacgcaa tcaactttcg cggcatttat cggtatgcta
     3061 gcaagtattc ttgtcctttt gtattttttg aagaaacatc aagcgtatac atcggcgttt
     3121 attcactaca gcgaaaacaa aataaatatt gcaacgaagg aattgttgtt agataccgtt
     3181 aaagaagcga ttccgtttat tattgtgggt tcaggggtaa cgatcttcaa attagtcgat
     3241 cagttcactt ttatgaagat catgtctgca tccaccgagt attccaatgc acagttactg
     3301 gatctttttt cgatttttag tgccaatcca gataagttga cgatggtagt tattgcattg
     3361 gcaacatcga tcgcgtctac tgggttaccg ttgattacag aagctgttac gttgaaagat
     3421 cgagtaggtc tggcaaaatt gacaagcgga aatttacagt tgttttcatt ttttatgttt
     3481 ccggcgacat ttggtgttat gttacttgcc tatccgctaa atacattatt ttatacaccg
     3541 gattctctag gaagtaatgt actgatccaa gcaagttttg taggactctt cctaggacta
     3601 tatatgctag tttccaacat gctgcaagga atgtttgaaa acaaggcggc aattaattat
     3661 ttggttattg ggtttctagt gaaactcctt cttcaatacc cagccattcg tttatttgaa
     3721 gtatacggcc ctttattggc gacaatgatc ggatttgctg tgtcttgtac cttgatctta
     3781 aagagaatcc atgaagtagc ccgctttaaa ccaagttttg tctggcgcag gacattgctg
     3841 atctttattc ttaccttgat tatgcttttg gcttcgtgga tcacaaagat gatttttggt
     3901 gcttttttaa acgaagatag caaattccag tctctattgt tgattcttgt agtagcaggt
     3961 ataggggctt tagtgtatgg ttatttagct ttgaaaatcc gcttggcaga aagactacta
     4021 ggaccaggaa tagcgcgttt acgacataaa ttaaaaataa aataagtgaa tcagaagagc
     4081 tagattgatg ctcttttgaa atgggggaaa cgcatgcgtt tagataagtt tttagcagat
     4141 atgggacttg gcagccgcaa agaagtcaaa ggattgatca aaaaaggaac gatcgaagtc
     4201 aatggacaag tggtgaaaag cgataaagcg caagtaaatg aattcgaaga tgcggttact
     4261 tatttaggag aaatcattac gtatcaaaaa gatttttact acattttgca taaacctgca
     4321 ggagtcattt ctgctactca ggataatcat gatcaaaccg taatcgattt attggaagac
     4381 caggattatc gggaagatct ttttccagtc ggccgattag ataaagacac agagggcctc
     4441 ttgattttaa cgaatgacgg ggtgtttgcc catcagttac tatcacctaa aaaacatgtg
     4501 gagaaagaat atctagctga ggttagcggt ataatgacag aagaagatat ccgtttattt
     4561 gcagaaggac tgattattga tggcgatgag cagacattgc cggcaaaact ccaaattgat
     4621 caagtagatc aagagacaga aacttcaatt atccgtctga ttttgcatga aggaaagttt
     4681 caccaagtta agcgaatggt caaagcagta ggaaaagaag tcttatattt aaaaagaatc
     4741 cgtatgggaa aattttggct gcctaaagat ttgaataaag ggcaatatcg acccatgacc
     4801 aaagaagagc tagaacaagt gagagaaaaa taattgaatg gatagctaaa agaataagca
     4861 gagtagttgt agcgccatct gaaaagcaga cttgtccgtc tgactttcgg atggcttttt
     4921 tgtgaaattt cggcttattt ccgtagaagc tacttctgga acaccgtttg ttcggaataa
     4981 gggactgtga caagactttt gttacagtcc ccattgttcc ttgtgactca gagttagata
     5041 gtaaggacac gatctcccta atactcaggc caaaacgctg aattcacaac ctctgataaa
     5101 cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata tgaggaacta
     5161 ttttcccgtt tttttctcta atactcaggc caaaacgctg atttcacaac ctctcctata
     5221 ctttgtttca ttttccctat actttgttta tttattctca ttattgaaag cgctataatt
     5281 acgttgcgaa tgaatcgaaa ggggttttta gatgaaaaaa cgaaaggggt tcaatcattt
     5341 ttttatgaat ctatggcgtt ataaagcact tgtcctgatg gctgtaccgg gtatgctttg
     5401 gatgattttt ttcttttaca tacctgtaat ggcgaatgtc gtagcattca aaaattttca
     5461 tatttcagca gatgggttct tggctagctt gagggaaagt ccttgggtgg gttgggaaaa
     5521 tttcaaattt ttattttctt cggatcaagc atttctcatc actaaaaata caattttata
     5581 taatgtagca tttatccttt tgaatctgct gatctcagtc gtatttgcaa tcattatgag
     5641 cgagttgaga aataaacgac tcgttaaagt ttatcaaacg atgtccttac taccttattt
     5701 tctatcttgg gtcattatca gttactttgt ttacgctttt ttaagtcctg acaaaggaat
     5761 attcaatcag tggatcactg gacatggagg agaagctgtc aattggtata atgaaccgaa
     5821 atattggccg tttatcttgg tgttcattgg tacatggaaa gggattggtt ataacagcat
     5881 tatttacttt gcatctgtta tgggaatcga tccgacttat tatgaagctg ctatggttga
     5941 tggagctagc aaatggcagc agatcaaaca tgtgacgata ccacaactta ttccactaat
     6001 gacgatttta acgattttag ccgtaggaaa cattttccga gctgattttg gcctgtttta
     6061 taacattcct aggaattccg gtgcattata tgatgtgact caagttttgg atacgtatat
     6121 ctacaatggc ctgacatcca caggagattt tggtatgacg gctgctgcag gactttacca
     6181 atcagttgtc ggctttgtct tgttgatgat cacaaatacg atcgcccgac gttttgatag
     6241 cgattctgca ttattctaag gaggaaaaaa atgaaaaaaa agaaagtgga gagagtccaa
     6301 gtccgctctt tcaataagac ggctaatttt ttctctaata taatgattgc actctttgct
     6361 atttcctgta ttttgccatt tatatttgtt atcgccatct cttttaccga tgagtccata
     6421 ttgtcgactc acgggtacag tttttggcca gaaaagttca gtatatttgg ttatacgtac
     6481 ttgttcgacc agatgcagga taaaattttc caagcgcttt tcgtcactgt acttgttact
     6541 gttttaggta cactgatcaa tagcacggct acttctttat atgcttatgc gatttcacgg
     6601 tcaaactttc cattccgtcg tttttttacc gttttttgtt tgattacgat gttgttctca
     6661 ccagggatgg tggccaatta tcttgttatg acaaatcttc ttcagttaaa agatacgatt
     6721 tgggcattga tcttgccaat ggctgtcagt cccttcaata ttattgtgat gcgcacattc
     6781 tttaaacgtt cggtctctga ttcgattatt gaatcggcac ggatcgatgg agctagcgaa
     6841 ctgcgaatat ttgttcagat cgttttaccg ttagctgttc caggtattgc gacaatcagt
     6901 ttatttgccg cattgggtta ctggaatgac tggttcaatg ctttactata catccaagat
     6961 gataagctag ttccactaca gtatcttttg atgaaaatcc aaagtaatat tcaatatctg
     7021 acacaaaatt caggagcagg aagccaattg acaggcggat tagcctcagt tccaggagaa
     7081 tctgccagaa tggcgatcgt agtcatctcg acgttgccta ttgcgatcag ctatccattt
     7141 ttccagaagc attttgtcaa aggtctaaca atcggcggag taaaagaata aagaaacaaa
     7201 aatataaatc ataaaattag gaggaagaaa aatgaagtta tggaagaaac tagcctttac
     7261 aggtgtttca gcgttgttgt tgggaacatt agcagcatgc ggaggttctg gttctaaaga
     7321 ccaggcagaa gctagcaatt cggacacttt gcagatgtat caaatcggag ataaaccaga
     7381 taatttcgat caattgatgg aagtagcaaa caaacgaatc gaaaaagaga tcggtgtaaa
     7441 agtcaatatc aattacattg gctggggcga ttacgaaaag aaaatgaacg tcatcatttc
     7501 ttccggggaa aattatgata tcgcctttgc gaacaactat gtttccaatg cccaaaaagg
     7561 agcctttgct gatttgactg aattagcgcc taagtacgct gaaaaagctt ataatgattt
     7621 agatgaagca tatattaaag gaaatctggt caatggaaaa ttatatgctt tcccagtcaa
     7681 tggaaatgtc tttgctcaac aagtacttac ttttaacaaa gctttactag ataaatacga
     7741 tctttcaatt gatggaatcc aatcttacgc tgatgcagaa aaagtcttga aggaattcca
     7801 tgaaaaagaa ccaaacacgg cagcttttgc cattggacaa ggcttcaaag tccaagggaa
     7861 ctttgattat cctttaggga atacgttacc atttgctatt gatctggatg gagatgattc
     7921 gaaaatcatc aaccaatacg ataatgaaac gtatatcgga ctgttacgta caatgcatag
     7981 ctggtacaaa caaggactca ttccaagtga cgctgcaacg agcaataagg attatccact
     8041 agaaggaaat acttggctaa tgcgtggaga aacacaagga ccgtatgatt atggcgatac
     8101 aattttgaca aatgcagcaa aacaagaact tgtctcaaaa gcaattactg ttccactaaa
     8161 atctacagct caagcacaaa tggcaaattt tgtcgtatca aatacttcaa aaaataaaga
     8221 aaaatcagta gaacttctag ggctgcttaa cagtgatcca gaattattga atgggcttgt
     8281 ttgggggatc gagggagaag catgggaaaa agtcgatggt tcagatgata aaatcaaatt
     8341 gctagatggt tatcagccaa atacacatat gtctgcttgg aatacaggaa acaacaagat
     8401 tctatataca caagagtcta ttacggatga catgattgcc aaacgtgatc aatcgattgc
     8461 tgatgcagaa acttcaccga ttttaggatt cagcttcaac actgacagtg tcaaaacaga
     8521 attaagtaat atttctaatg tcatgaatca atatttagat ggattgaata cagggactgt
     8581 tgatccagat gaaacattac cgaaattgaa agacgctttg gacaaggctg gctatgataa
     8641 ggtattgaaa gaaatgcaaa aacaatatga tgagttccga caagaataat aatgaataaa
     8701 gacaaagggg ttgtgacaaa agacgtgtca caacctcttg ttccgaataa acggtgttca
     8761 aaagccagtt tctcggtatt aagctaaata tatgtaaaaa tgtggaaagc catattcaca
     8821 aaatttttct tactactcga aactaagcgg ctatttcaca aactcttggt aaacggtgtt
     8881 caatcagcta accctcggta ttcgctcaca aaacgacaaa atatgaggaa ctatttttcc
     8941 gtttgtttct ctaataatca ggtcaaggtg ctgattgccc aacctttttt tgtataatga
     9001 gaaagtataa acttaatgtt tggaggagaa gatatgttag ggaaggtttt ggaagagtta
     9061 tttatccgga tctgggtcat tataaaacta accttgtatt tctggatata tacatttgcc
     9121 ggcgggatca tctttggatt aggtgcggca tggaaaacag tcaatgaact attttatttg
     9181 tacggattcg agtataaaga aatcacaata aaaagaggct ggaatatata taaaagaaat
     9241 tttttaagag gcaatctgct atttagttta tttttatctg gtactgcttt attgagttac
     9301 aatttatatt tatctgttca aatcaaaggg ctcatttttt tagctattga ttttatttta
     9361 ctttttgcct tgctctgcct atttgctact tatcaataca gtatgatttt agatagtgaa
     9421 tatacgatct ctgttcctaa tctgctaaag ctaagtttta tttcggtttt ttccagcttt
     9481 tcgtcttttc taaaaataat tattggtagc ggtataattt taggcgtgac ttggcaattc
     9541 aaaggattga tcctgtttgg tgtcattggt cttttgacgg tttggaatgg tacgatgaca
     9601 acacattggc gtgaagaatt agataaacag ttggaaagtt atgaataagt ttcggattct
     9661 attttcaaaa ggaaccttac taaatcgtct gttgcggaaa tacgcggtta tcatgatcgg
     9721 tgtaacgatg actgctaccg ttatttttag tatccatact tgggaacaaa atcaaaaaca
     9781 ggcagaaaac atgacaagtg atgccgttca aagcacaagc agaatgctga atgataaaac
     9841 aaccttgagt aggatcatca aaaaccagct tgtagggaat tccgaaaaga tcgaaaatgt
     9901 gacgacctac ttaacaaaac ccatagatca gtatctgatg tatgtatacg aacagcaaaa
     9961 cagtaccgat gaattagttt ctttcccaaa tcaaatcaaa gatctctacg caaattatga
    10021 agaactaagt gcgatatata tcgtgttgaa tcaactaccg gagtattatg aatcttctag
    10081 agaaaacaaa ggtggggaaa taaaaaaggg gacaccaaaa ttactagacg ccttttatat
    10141 caagttgcct atcacacaag gaggagctga gtcaggaagt atttttattg gttttcaaaa
    10201 gaaagaacta gatatgattt tagaaaatct aacgtcattc aatggactct ctttatacat
    10261 gatttctgga acgacaaatc gactatacac attccatgat aataaaatag ctaaagaaac
    10321 gtttgaaaga caagaaatga tcatcacaga gagtctgaag aaaaattcac aattgccgat
    10381 tgacgatctg gaaaaaaaca attttgttca acaccaagaa ctgtctgatg attatcgtat
    10441 attagctgta ctagataaaa aaagtgtaaa aatcgaaacg ggaaaaaatc ttgccccgct
    10501 gatcattggt atcattattt tagacaatat actgcttatc tttctttata aaacattcaa
    10561 acgatattca cagcaagtat ctatcgtcat gcaggccatg gatcaaacag cagcagggaa
    10621 tttagagacg cggatcgaca taacaaacac ggaatatgaa ctgaaggaac tttcaatcgg
    10681 tatcaacgaa atgttggata gcatcaatca gtttgtagaa gacatctaca aattagaaat
    10741 caaacagcaa gacgcacata tgcgggcgct tcaagcacag atcaatccac actttttata
    10801 taatacatta gaatatatcc gaatgtatgc aatcagcgaa ggaagtgaag aattagcaga
    10861 tgttgtgtat gcgttttccg ctttgcttcg aaacaatacg aatcaagaga aaacgatcac
    10921 tttaaaagaa gaactggact tttgcgaaaa atatgtctat ttgtatcaaa tgcgttatcc
    10981 taatcgagta gcctatcatt ttatgatcga tcctgatttg gaaaagatcg aagtacctaa
    11041 atttgtgatc cagccattag ttgaaaatta ttttaaacac ggtattgatt ttactcgatt
    11101 cgataatgcg ctaagtgtca aagtcttgca ggaaggcaaa cgggtaagga tcatcatcaa
    11161 agataatgga aaagggatga ctgaaaaacg gctaaaacag attgaagaaa aactgtctca
    11221 tcctaaagtg gaacttcacg gttctatcgg tctgcaaaac gtgaatgaac gtttacgtgc
    11281 cagcttcggc agcagttatt atatgtcgct tgagaataat gagacaggtg gactgaccgt
    11341 ttctattaca ttcaaggagg gatgagcgtg tatcaagtgt tattggtaga tgatgaatac
    11401 atgattttga atgggttaaa aaagataatt gattggcaaa gtttaggctt tcaaatagta
    11461 gcaacagcag agaatgccaa agaaggacta gctgtacttg aacagcgaca gattgattta
    11521 gtagtaacgg atgtgacaat gccagaaata aatggactgg aatttattga agcggctcaa
    11581 aaagaacgtc ataattttga atttatgatt ttatcaggat accaagaatt cgattatttg
    11641 aaaggaggta tgcaattagg cgccgtgaat tatttgatga aacccgtgaa taagttcgaa
    11701 ttggttgaaa gcctcaagaa aatcaaaaca cggttagatc agcaaaatga acaaaaaaat
    11761 caacaagaaa tctatcaaga actgttattc agtcaatggt tgaatgaaga attggatgaa
    11821 ataagtgaag aagaaataat aggacaaata agtgagaagc agcataggat agtattgatt
    11881 caactggcaa gaactcatga tactcttatc aatagatggt tgcaagaacg gcaacaaatc
    11941 ttttactatc aacgaaatta cggagaccgt gtattgatca cgttgttgtt ggaggcagat
    12001 gaagttgatg gcttctgttg ttttgttcaa gaaaactttc ctgatcagga atggctgatc
    12061 agtatcgggg aagagacaga ttctttggac aaaatccctg aaacattcca acaagcgaaa
    12121 gacaatctac agttgcatca attttatgga gataaagacg agcatgtttt ttacgcagta
    12181 caagcagaaa caaaagatca aaccatcgat ttttcaagtt tcagacgcgt gctgcaaaat
    12241 aaacaattgg aagtcgctca aaaaatgatc actgattttt ttgaacagtt tcagttagca
    12301 gccatgatgc cggaagatat acgatattcc agttttttac tgtttatgga gattcaacgg
    12361 gaattgattg atctggaaga tgaggaatat ttacaaggaa tcgaaaaaat ccatcaggca
    12421 aaaacggtgc aagaacttca gcagctactt ctgtcattca tcaaaaagca tcagagacag
    12481 aaaaagtaca gtgacaatgt ggaaaaagta atcgtaatcc tgcaccagca ttatcaagaa
    12541 ccacttacac tcaaagaagt gtcagaaaac ctgcatttaa atgtcatgta tctaggacag
    12601 ctgttcaaaa aagaaacgaa aaaaagtttt tcagcttatt tgaaccattt acgtatggaa
    12661 aaagcgaaac aactgctttt gcacagtaat caaaacatca atgagatagc aagtgagatt
    12721 ggctacaaca acaccacgta tttctctaaa ttattcaaga aaatcgtcgg cagatcccct
    12781 aaagagtacc gagaaaacag tggagaatca taaaaaaaaa agccaatgta atgaaataac
    12841 ttataaaaaa ttgtctagaa atctaatttt gggctgttct tattacttga ggcaaggcag
    12901 ctttttcatg acctctcgat aaacggagtt caaaagccag tttctcggta ttaagccaaa
    12961 tttatgcaaa aatgtggaaa gccattttca caaaattttt cttaatactc gaaactaaac
    13021 agctttttca cgacctctcc actaaatggt gttcaatcag ctgaccctcg gtattagctc
    13081 aaaaaatggc aaaatatgag gaactatttt gccatttgtc tctctaatac tcaggtcaga
    13141 acgctgattt cacaacctct caataaacgg tgttcaaaag cttgcatctg cggtaataag
    13201 accaaccaaa cgaaaaatat gaggatctat ttttgcttgg ctgttcttat tacttgatgc
    13261 aggacagctt tttcacaacc tcttgttaat tatagtttga taaggaaaaa ggcaaatctt
    13321 ttgcttgata tttcttaggg tgagggatga tccctaattg gtaagagatc gtgccgcctt
    13381 tcagcaaatc ttgatgggta aaatataatt tcgtatattc tctgtccatc cgtttgattt
    13441 tatggataaa ttgttgctgc ggccgattag gcgttgcttc aatcgtcaat tcctttccat
    13501 ttgacaaaag caaaacagcc ttgtcaatta atggcatacc gataacatat tcaccggttc
    13561 caggcgtgac aggataaaat cccagactat tgaagatata ccaagcggcc atacttccat
    13621 tgtcctcatc tccagggtaa cccattggag aatcgtcgaa ggtctgagtc atcaactgtt
    13681 taagcagtgg ctgtgccatt tcaggttgtc ctatataact gaacaagtaa ggatagtgaa
    13741 aacttggctg gtttgaaata gctaattgtc caaattctat cgcggccatc tcactcattt
    13801 cgtggatctc aaaaccatat cctcctgggt caaacgttgg gggctgattg cacagctcaa
    13861 tgagtttttc tttatatctc tcactgccac catattttcc gatcagtcct gaaaaatcgt
    13921 gataaacagc aaagctgctt tgccaagcac ttccttctgc ataatcttgt ccccaacgat
    13981 tagctgaaaa tggttctctg aacttgccat ctttatcttt tgaacgcata aatcctgact
    14041 catagtcaaa gatattttga tagttcaatg attgctgctg atatttcttc gtcatttcct
    14101 cttcttctag taccttggca acttggctaa tacaaaaatc gctataagca tagtctaatg
    14161 tgtgattgac tgattcgtgg tagtgattag gaacatagcc atatgtcaag taatcttctg
    14221 ttccttggcg tccataattt ggatgtttgc tttgaaccgt agcacctttt tccattgccg
    14281 ttagaaattc aggcatcaag tctcgtcgga tatcttttac agcagcatct gcaatgaccg
    14341 catcgatcaa tgtcccaggc ataagtccac gttcatcagg agacagccat tttggcaaat
    14401 agccactttc tctatagctg ttcaaaaaac cttccagcat ttcttcgtat ttttctacag
    14461 caatcaaaga ataaagagga taaaccgttt tatacgtatc ccaaaaccca ttatttgtat
    14521 agagaacacc aggttttata gatcgactag tcgtatcata gtggattttt tgcccactag
    14581 gatcaatttc ataaaatgtt tgtggaaata aaaacacccg atataaatta tgataaaacg
    14641 tccgcaattg ttgttgatca tggtgtgtga gctgtatacg atcaaaatag gactgccatt
    14701 gttcttgact gtgagcaagg taagtctctt tgctttggtt ttgttctagt tccaggttat
    14761 aagctgcttg ttccgagctg ataaaagatg tcccaaatcg gatagtttgt ttttttgtct
    14821 gttcaaaata caacgggatc gagtcgctat ttttgttgga aacagctaac tcatcaattg
    14881 ttaaaggata ttcaaatctc aatataaaat aaaaagaaaa atcaggatct tctgaaccag
    14941 caaaatgtgt gatttttcct tccactgtgt aaggatctat aacaaagagc tgatggcgtc
    15001 ccggaaagga taaaagtaaa ccgctgtcat ttttgctgta atcaatagat aagattccgc
    15061 catacatgct aggtatcaat gtagaacaga tgccataacg taattgacag atcgacagat
    15121 gagtcgggca aaatatactt tcttctgggc ggtaagaact ttgagcatgg aaaagggtgt
    15181 tctcctgtag ttttccattg atcggcgtaa acagcatatg actgaaatca cccatccaag
    15241 gacttggttg atgggtaaga cggtagcctt gaaaaacgcg gtcatcagga tgaaaccacc
    15301 agctgccgtt ttgatccgta gtttgcggtg caaaataatt catcccaaaa ggaacgccag
    15361 tataaggctg gcagttccca ttagagaaat ttggctgatt cgctgttgca tgtctagtat
    15421 ctatttgacc gatattcatt ttatttctcc tttgttgatt gtcttttgat gaatgaaact
    15481 ggaaatttac tatcggatgg tcgatctttt gtctctaacc aagtgaccaa agcatctccc
    15541 gcaagcttac ctaactgttc aaaatcttgt gcgatggttg tcagtggcgg gtcaacaaga
    15601 gctgctgctt ggatatcatc aaatccgata attgaaaaat cttcagggat atgataacca
    15661 tgctgtctca agagattcat ggtctggata gcgacaacat cgttttcaca aacaaaagca
    15721 gttacttcat acttagtgat ataagaaagc aattcatcta atgtcgcgct tttgtcatcc
    15781 agtgaagtgt ggaaagtcaa accagctttg tccaatgctt caaggtaacc aaggtaacgc
    15841 tgtcgaacgg attgtggatg agtctgcgta ccaaacaaat aagcgatttt tgaatgtccc
    15901 tgttcgatca aataagaggc agcaagcgca ccgccttgga aattatcgga aagaacggta
    15961 ggaaaaggta actcatagat ttttttatct aatatgacga cagggaattc tttcaatgaa
    16021 agctcaaaaa gtaagtcaag atgttgttct gtatcaagag cataataaat caatccgtca
    16081 aattcattga ttagctcttt tgctgtttta ttttgtagaa agtcaagcgt cgtcatcatg
    16141 acatcaatct gtttatcttg catcacaggg ttcaatccct tgctaaaatc accaacagac
    16201 aaatcagcga catatggaag aagaaacaga atccgtcgtg tttttgtagg agaagcaaga
    16261 atctgttccg gagaagcgga tttaacgaaa ctgcctttcc cgcgaacgcg ataaataagt
    16321 cctaattgct ctaattcagt caatgcacgt ttggaagtga ttctgcttac tttataggta
    16381 cgtgaaagtt ctttttcagt tggtagttgg ctgtctacag gtaattcacc agttaaaata
    16441 gccgtttgca aatcattaaa tattgtctgg tacaatggtt gagtcatata aacacctctt
    16501 aatgatatat catattcaaa taataccata atggatgaaa aagtaaataa aaagatattt
    16561 tttgaaagcg tagacataat tggctgtatg aagtataatc tttaaagata tatcaaatag
    16621 aaagaaggtt ttattagtgg tttataaaga tataccaaaa tcggtgcaga aatttatgga
    16681 agatatcaca caaaaatgtg gggatatcca tgcggactgg gcaaagaatt ttacagcagc
    16741 atttgccaat actctgttga caacagtcaa aaagcaaaat gacggaacca cctttttatt
    16801 gacgggagac attccagcga tgtggttaag agactctact gcacaagttc gtccttattt
    16861 agtgattgca aaagaagatg aggaattagc tgacatgatc agcgggttag tcaaaaagca
    16921 atttttttat atcaatatcg atccatatgc gaatgccttc aacgaagaag ctaacggtgc
    16981 tggccaccaa acagatcata caaaaatgaa cgattggatc tgggaaagaa aatatgaaat
    17041 tgattcttta tgctacccaa tacagttggc ctatcttctt tacaaaaata caggaaaaac
    17101 tgatcaattc aatcaatctt ttattgaagg tatcaaaaaa atcttggacg tgttcaaaac
    17161 agagcaagat catgaacact ctccttatac atttgtacga gacacgacaa gaaaagaaga
    17221 tacgctgatc aatgacgggc gaggtgcaaa aacagctttt acaggaatga catggtctgg
    17281 tttccgtcct agcgatgatg cttgccgtta tggatatctg gtaccatcca atatgtttgc
    17341 ggtggtcgtg ttaggttatg tggaagaaat ttttcaaacg atactcgatg ataaagaaat
    17401 tgtacagcaa acacagaaat tgaagaaaga gatccaagag gggattcaga atcacggacg
    17461 aacggttaat caaaaagggc aaacgattta tgcatatgaa gtagatggaa tgggaaacgc
    17521 cacagtcatg gatgacagta atgtgcccaa tctgatcgcc gcaccttact tgggatattg
    17581 ttctgaacaa gaggaagatt atctgcaaac aagaagaaca ttgttgagta aagaaaatcc
    17641 atatttctat gaaggaaagt acgcaaaagg aattggatcc tcccatacgc cagaaaaata
    17701 cgtttggccg attgcattag ctatggaagg aatgacaacg tcagacaaat ctgaaaaaga
    17761 gcggatattg aatttacttg tagcaactga cgcaggaaca caccttatgc acgaaggatt
    17821 cgatgtgaac aatcctgaaa attatacgag agaatggttt tcttgggcaa atatgatgtt
    17881 ttgcgaatta gtcatggatt actttgatat tagagtagaa aagtaggagg tatcgtaaat
    17941 gaaaaagaaa gtatatatca tttctcatag ccactgggat cgtgaatggt acatggctta
    18001 cgaacagcat cacatgcgac tgattgaatt gatagacgat ctactagagc tatttgaagt
    18061 tgatccgtcc ttcaacagtt ttcatttgga tgggcaaacg attattttag atgactatct
    18121 tcaagtaagg ccagaaaaaa gacaggcaat ccaacaagca atcaatgaag gaaaattgag
    18181 aattggacca ttttatatct tgcaagatga ttttcttatc agctcggaat cgaacgtgag
    18241 aaatatgctg attggcatgg aagaaagccg taaatgggga acccctgtca tgttaggcta
    18301 ttttcccgat acatttggaa atatgggaca gacgcctcaa ttaatgaaac aagctggtat
    18361 ttcagcagca gcgtttggcc gtggtgtaaa accaattggc tttgataatc aagttttgga
    18421 agcagaaaac tattcttccc aatactcaga gatgtggtgg aaaggccctg atcaaacagc
    18481 aatctttggt ctgctatttg ccaattggta tagcaacggg aatgagattc cagtagaaaa
    18541 agaagcagct cttgcctttt ggaagcaaaa attagcggat gcagaacaat atgcctctac
    18601 gaaccactta ttgatgatga atggtgttga tcatcaaccg gtacaaaaag atatatcaaa
    18661 agcaatccat ctcgcaaatg aactgtttcc agattacgag tttattcatt ctaattttac
    18721 tgactatctg gaagcagttc aaaaagatgt gccagaagac ttaggctcag tagaaggaga
    18781 attgacaagt caagaaacgg atggctggta tactttagcc aatacagcat ctgctcgggt
    18841 ttacttaaaa caatggaata ccaaggtcca gcgacagcta gaaaatatta cagaaccact
    18901 tgcgacgatg gcttatgaag ttagtggaaa ctatccccat gatcaattag attatgcttg
    18961 gaagacatta atgcaaaatc atcctcacga cagtatttgc ggttgttcag tcgattctgt
    19021 ccatcgggaa atgatacctc gttttgaaaa agcagatgaa gttggaaagt atcttgcaca
    19081 agattcctta gaacagctga ccgcagcaat cgatacgacc ggattcccaa aagacagctt
    19141 tccatttgtc attgtaaata ctgcaggaat ggataaaact ggtgaagcag aaataaccat
    19201 cgaattagaa agaaaaagat tcgctgaagg aatacctgaa caactatatc aagagttaga
    19261 aaatttgcct aaacgtaagt atcatgtaga aacaaaaagt ggggccacta taccagctat
    19321 tttatctgaa gaaactgtcc aatttggtta tgatttgccg aaagaccgtt tccgtgtgcc
    19381 atatatggca agaatgatca aagtgacttt accattagaa aacatgccag cattttcttg
    19441 ggaaacattc gcgcttgtag aaggggaagc gaaagcagaa gaaaaggaaa caatgattca
    19501 tcagagtgga cgaatcatcg aaaacggccc tctacatttg acgattgaaa aaaatggtac
    19561 cattacaatg gaagatcgca aaaacaaacg aaagttgaat aatctgcata tttttgaaga
    19621 tatcggcgat ataggaaatg agtatatctt taaacaacct ttctgtgatc agccaatcct
    19681 atccagtaac aaagaaaact ctgaagtaaa agtattagta gatacaccgg aaatagcaaa
    19741 aataagtatt ctacaggaaa tggaaatccc tgtttctgca gacgagcgtt tagaaaaaga
    19801 acagcagatg gttgtggaat ttcgttatcg aaaagcagaa cgatccaaag aaaaacgaat
    19861 ccttcaaata aaaacaatca tgacaatcag aaaagatagt aaaaaaatcg actttgaaac
    19921 gactctcgac aatcagatga aagatcatcg cttacgtgtc ttgtttccta caaagttaca
    19981 tgtggaacat cacgaagcag atagtatttt tgaagtggtg aagcgcccaa accatgtgtc
    20041 taaaagttgg gaaaacccca cgaatccgca acatcagcaa gcatttgtca atattcatga
    20101 tgaagagtac ggtgtaacag tcggaaactt tggtttgaat gaatatgaag taacagaaga
    20161 cggacaaatc gcagtgacgc tacttcgcag tgtgggagaa ctaggcgatt ggggatattt
    20221 tccaacacca gaagcacagt gtctaggtga gcatcggttc aattacagca ttgaactaca
    20281 tggaccagaa gaaaaattct ctacttattt gcatgcatac gcagcacaga ttcctttttc
    20341 cactcaacaa atcaaacatc atgaaggaac attgatttca aaacaacaat atttaacgat
    20401 aaaaagtgaa acgtttgcaa ttacagcttt gaaacgcagc aagtttagtg ataaagtagt
    20461 agtaagaggt ttcaatatgt ctagtcattt agaaaaattg gaaataacta aagacaatgg
    20521 aaaaactgtc atattgaatc tgcttgaaga accaacgaag caagcggttg tcccaataat
    20581 ccaaccttat gagattcgga caatcggatt cgaggaggaa aacgaatgta tggcggaata
    20641 gaagcaggcg gaacaaaatt tgtgtgtgcg gtttcagatg gtggagaaat tttagaaaaa
    20701 ttaagtatcc ctaccacaac accagaagaa acattggatc aggtatttga attttttgat
    20761 cgttatgaat tgaagggaat cgggattggc tcattcggcc cgattggtat cgacaaaaca
    20821 aaagataatt acggatacgt tttggcaact cccaaaaaag ggtgggcaca attcgatttt
    20881 cttggcacaa tcaaggaacg ctacaatatt cctgctgctt ggacaacgga tgtcaatgct
    20941 gctgcatatg gggaattgaa gcaaggagca gcacaaggaa aaaatagttg tatttacctt
    21001 accgtgggaa caggaatcgg tgcaggtgtc gtgatcaatg aagaaatttt ttcagggatc
    21061 gcacatcctg aaatgggaca tatttgggtg aaacgccatc cagatgacca ttatgaaggt
    21121 acttgtcctt atcataaaga ttgtttagaa ggattagcag caggaccgtc tattgaggca
    21181 cgcacaggga tcaaagggca agatctgccg caagatcatc ctgtttgggc tattcaggct
    21241 tattatattg ctcaagcact gatcaactat acgttgacgt tagcacctga aaagattatt
    21301 ttaggcggtg gggtaatgaa tcaggatcat ctccttcaaa aaatccgtca gcaatttgtt
    21361 gaattgatgg gtggttatat ggaaacacct caagtaagtg aatatatcgt tcgttgggga
    21421 ctgccgaatg aaagtgggat tatcggtagt ttgctgttag cagaacacga acatcaaaag
    21481 taagcagaca aattacacaa aaagaacaga gtcttatcat tatctgctga taagactctg
    21541 ttctttttta tttctattcc cataatccag gtaaagcttt accgactatt ttttcttgag
    21601 taaatggatg gatcatgtgc agttctaatg catggagcat cagtcgttca gctgttctat
    21661 tttggtagag agggtctcca acgatcggat gtcccttatg agctaaatga actctgatct
    21721 ggtgtgtacg tccggtttcc aaaacacaat agacttgtgt ttgttcagaa agtactttgt
    21781 tgacagtgac atgtgtcaag gcgctctgac catttttatc atctacgacc ctttttctcc
    21841 gatcatggcg atctcgtcca attttattgg tgatggtcat atctttggca atttctcccc
    21901 atacgatggc ttgatatctc cgatagatca ttttttgttc caacattctt ccaagtatcg
    21961 gcaagacaaa tggatttttt gcaaataaaa cggcaccgct tgtttctttg tccaagcggt
    22021 ggacaacgta aggtcgttgc tgtttagtgt cgagataagc agctaaatga ttgagtaagg
    22081 tactgttttc tgtcggttca tttggatgag tcttcattcc tgcaggctta tccactataa
    22141 tcaaatgctc atcttcatat aaaacacgga tgtgcttcgc atctcctaat tgaacttctt
    22201 gataattata atctgtttct tcgaataaca atgtgatctg gtcattgccc tttacttcat
    22261 gatggaacaa agcaggttgt tgattgatcc aaacgttttt acgtatacgc aaaaagtgtc
    22321 gaacctttct aggaactaac cattcctttt caagcaagtc gcgaattgtt gtttcaggat
    22381 ggttcatagg taaagtgatc gtgattttca caagtgtact cctttcagtg caatcgcaga
    22441 ctaattgtac catttttaaa acatatttaa gaaaaaactt acatttttct gttcattctt
    22501 atgttactct acttgcacta acgtaaaaaa acatattgaa ctacaactta agcaggaaga
    22561 aaacactctt tcactatggt aaaataagac gattgaatca aatagacagg agaagaagca
    22621 aatggatttt caaagcattt tagaaaagat aaaagctgct ttgatcagtt tttggcgttg
    22681 gatcagacca tatctcggac aattccatcg atggcgaaag cgcatctgga aaaaatatca
    22741 tgtgaacaaa ttgattttgc tgattggttt gatctgtgtc ttagtgacaa gtatctacct
    22801 ctttatttta gcaaaacaag caaatgtcga aacgttaaaa tcaggattaa gccaatcgac
    22861 agtcatttat gataagaaaa acgaagaagc tggcacactg tacgcccaaa aaggaacata
    22921 tgtagaatta aacgcgattt ctccctatat ccaagatgca gtaatctcga cagaagatag
    22981 gaatttttac gagcatcacg ggtttgatat caaagggatt gcccgtgcag cagtccgaat
    23041 ggtcttgtct ggcggaacat cagggggcgg aggaagtacg atcactcagc agcttgccaa
    23101 aaatgcgtat ctgacattag accaaacgtt tgatcgaaaa gcgaaggaat tatttttggc
    23161 aatcgagatc gaaaagaagt acagcaaaga agaaatcttg accatgtatc ttaacaatgc
    23221 ctattttggc aacggggtat ggggtgtcca agacgcttcc agaaagtatt ttggagtaga
    23281 tgcaacgaat gttacgctgt ctgaggctgc tactttggca ggaatgctga aaggtcctgg
    23341 tatttataat ccgatcgatc acccaaaaaa tgcgaatgat cggaaaaaca cagtactaag
    23401 tgtaatggaa gaaaacggaa aaatcacaaa agaacaagaa caagcagaaa gccagacaga
    23461 tatcagcgcg tatcttaatg acacatacga taattcagat tctggttatc gttatcctta
    23521 ttattttgat gcagtgatcg atgaagcagt taacgagtat ggtcttgatg aagaagatgt
    23581 catgaataaa ggctataaaa tctatacagc tttagatcag gattatcaaa agcaattaga
    23641 agctacttat caaaacagtg cattattccc agcaaatgct tcagatggtg ccatggtcca
    23701 atctgcttca gtagctttag atccgaatac aggtggtgta caagcactag taggacgaag
    23761 aggagatcat gtctttagag gattcagctt tgctacacag atgcgtcgtt caccaggatc
    23821 aacgatcaaa ccattaagcg tatatacacc agcactggaa gctggataca agccttccag
    23881 tatcttgaaa gacgaaccgc aaagttatta cgatgcgcat aattttgacg ggacatacca
    23941 aggagaagta ccgatgtatc aagctgttgc acaaagtttg aatttgccta ctgtatggct
    24001 tttgcatgag atcggtttac aaaaaggata tgataaagca gaagaattcg gcctgccttt
    24061 agcaaaatct gataagtatt atggcttagc ccttggtgga ctggaaaaag gagtatctcc
    24121 attgatcatg gcgggtgctt acagtgcatt tgccaatgat ggtcagatgt atacgccgca
    24181 tcttatcacg aaaatcgttg attcgactgg agcggtgatc gtcgataaca caaacaaaaa
    24241 accaaaacag gtcatatcaa aggaaacagc cgatgaaatg accagcatgc ttcttggtac
    24301 attttcaaat ggaacagcgg ctgctgcgaa tcctgcaggt tatacgatag cagggaaaac
    24361 aggaaccaca gaaactaatt tcgatgccac aaaagcaaat gaccaatgga tgatcggtta
    24421 cacgccagac gtagtgattt cgacatggat gggttacgaa gaatccagca agctgcacta
    24481 tttggaaggg acaagtggaa atgttgtcgg gaaagtcttc aaatcagcgg cagaaggcat
    24541 ccttccgtat acttcaaaaa caggatttag tgtagcagat gcctatgcca caggaggaca
    24601 agtggtagct gcagatcaag ttggaaacac aggaaattct aatggagagt ctggaaattg
    24661 gcaagataac ttgaatcaat atggtgaaca agcaaaagaa gggctgaaaa acttcggcga
    24721 tatggtgaaa gaaggcgttc agggaattgg tgaagcggct aaagacctct ggcggaaata
    24781 tcaaggagag tagccccttt gaaaacgaat aaccccatgt tacaatagag agtaactact
    24841 aaaagaaaag agggcataac atgtcaaaca tctacgatag cgcgaatcaa atcgaacgtg
    24901 agatccgtga attaccagaa ttcaaagcgt tgaaagaagc gtacgagaaa gtacaagcaa
    24961 acgaagaagc acacaaactg ttcaaagact tccaagcgat gcaaatcgaa ttacaagaaa
    25021 aacaaatgag tggacaagag ttcagcgacg aagatgcaat gaaagcacaa gaaatggctg
    25081 tgaaaatcca atcagaagaa gtaatcaatg acttgatgca aaaagagcaa ggcttcagta
    25141 caatcatcaa tgacttgaac cgtatcatca tgacaccagt tcgcgacctt tacagcgaat
    25201 aaaactattt tatgaaacaa cagagggtgt gaaagagacg ttcggccttg agcgatgaca
    25261 aaattgcttc ttattgccga taggctgtct cttgaacacc atttaccaag aggtcgtgag
    25321 cctaccgttt aactctgagt tacaaggaac aatttcaaaa aacagcttct catgtttgat
    25381 gactattgtg acttgtgacc gaggagttgg caggagaaca ccgtttattc agaaatagga
    25441 gctacgacaa aagtcttgtc atagctccta ttttttgtca ttcatttttc aagcggtaga
    25501 aatagccttt ttgagctaac agtttttcgt aagtacctat ttcaacgatt tttccttcat
    25561 cgatcacaac gattttatct gcctctttga tcgttgaaag ccgatgagcc acaataaaag
    25621 tagtgggtgt ttctgtcagg taattcaggg cttgctggat ttttttctct gactggttat
    25681 ctaaagctga ggttgcttca tctagcaaaa tgatttttgg ctgacgtatc aacgctcgtg
    25741 caatggagat acgttgcttt tggccaccag acagcttgtt gccatgttcg cctactaagg
    25801 tatccagacc atcaggaagc tggtcaatca gtgaagaaag ttgcgcagct tcgatgactt
    25861 catctaaacg ttcttttgat acgtttttca agccataagt gatgttctct ttgatcgaag
    25921 cggagaacaa caaagtggtt tgaggaacaa cggctaaata atttcgcaca cttcgcatat
    25981 ccagttcatc caaaggctga tcatctagaa aaatttttcc tgaagtcggc tggataaatc
    26041 caatcaataa gttaaggagt gtagattttc cagagccaga tggcccaaca aaagcaattg
    26101 tttctccagc tttcacctct agagaaaaat gatcgataat cggtttgagt gagtccggat
    26161 aaagaaaaga aacatcctca aaacgaaaat ttccatccaa atgttggatt tttttcttac
    26221 cgtgataagt ttctacatcg ccagcaatca acagttcgcc aatagaagtg atagattcca
    26281 tgccttttga aatcgtagga atcagcgtga tcattccaga aacggaattg acgatcgtcg
    26341 tgaaatacgt ctgatacatc acgacatcgc cgggttggat gcgcccttgt aaagctaata
    26401 tcccagtgaa aatcaaacaa atcagctgaa atatctgaaa actagcccag ctgactgatc
    26461 cgaaaacaga ttgcaggata tctaagtgga atcctttttc atagatttga gtaaaatgct
    26521 tatttaagcg agttgtttcg tgtttttcta acccatgagc tcgagcaatc ggtgctaatt
    26581 cgatcacttc gatcactttt gcagaagtct cttccatttc ttgcctgaag tctgagttgg
    26641 actgtctgat ccttttacgg aaaaagagag taacgaatgc ggcgagagga acagtcaata
    26701 agaaaaacat gaaaacaaca ggacttttat aaagcgtgat acctaaagct acgaataaat
    26761 tgacagcgat atttaatccg ctgacaaata cttgagagga caacgtttgg atagcttcta
    26821 catcacggat gatctttgac tggattcgtc cagattgcaa ttctttttga taaggaatag
    26881 atagttcttg gattttcttg ataagggtcg ctcttagtcc agcttctact tgacggatcg
    26941 aagtgctatg gtattttaca tgaaaataat tcgtcaatat attttgacca atcagacaag
    27001 ccatcaaaaa agcgttgaaa taaatggcct gcaactgaga agaatctttc gatgaagctg
    27061 cattgattac attggcaata gcgatcggca ttaaccaaga tggaagatgt ttgataataa
    27121 aaaagagtcc tgacatggca aaacgccaat aatttccctg ataaagatgc agcaatgtct
    27181 gaaaagcatt tgcatgatat ttttgataac ttttctgtat tcgttcctcc ataatcttct
    27241 ccttaacaat cttggtaaat aaactgcaag tgttctattg cttcaggaac ataaatctca
    27301 ggagtagctt caagagtggc gtacattaga ggacgctcat atttgatata atgcagtacc
    27361 gggcggaaat ctaaacagcc cttgccaaca ggtaccatgc ggatctttcc attttccatg
    27421 atatagtctt tgagatgaag cgctgtaata taaccatgta aattgtccaa ggcacctcgg
    27481 atcacttttt cctgatcagc atgattttct ttatgcatca aattcgcaca atctaaaatg
    27541 atttttaaat ttggtgaagc tacttcatcg attaaacgtt tagctaactg atagttatag
    27601 attggatgat tgatccctgc ttcaacagca acagttacgc caaaattttc tgcatgagcg
    27661 actaattcaa tgatagaatt tctggcgatc tgataagctt cttcagtaaa attttctttt
    27721 gtgtaaccga cagagacact accggtttcc gtagcaatca tcttggcttg ataggcagag
    27781 cacagagcaa tttgctgttt gaaagttgcc aatgcttgtg cacgaacttc ttgatttttg
    27841 ctggataggt tgatatagca tcctaaaatg gaaagttcga tattgttttt ttggaagtat
    27901 tcaccaaaat aggcagcact cccaagtgtc atgtcagtta atttaagttg ttcaggaaat
    27961 gctttttgtg gtgcaaattg gatatgggac aagtgaagct gtgatacttt ttgaacgatt
    28021 tcttcacgat ttcgaacatc taaatcgtgg gcacggatgc ctaaatttaa tggaaacatc
    28081 tcaaactcct ttttgtaaat aattagcaag aggcagacgg gattctttta tcaattcaac
    28141 aattattcgg gcaactttat cagcgccttc tggactaaag tgggtattgt cttttagtcc
    28201 ttctgggtaa tttttacaag tatcaggtat aagatgcagg tagaattttt ttgtctcttc
    28261 ttttgagaag gtctggaaca attcttgtga tcttgagaac acatctaaaa gaggaatatg
    28321 gtgtttctca gcaaatgcac gcatcgcttt tggatagtct ccaagtatat ctggattcaa
    28381 tgttccgttt tctaagtaat ctcgtcgcgt cacagatgtc agtaagacca tttggacgtt
    28441 cgcttttttt gcgcattcaa aaaatatctg cagatttttt aaatagctac cgaagggaag
    28501 cgtacctctt tcttcttgga ttttctggtc gttatgtcca aattgtacaa ataagaaatc
    28561 attcggctga aactgtgaag ctagacgggc taaccttcct tcctggataa atgatttggt
    28621 gctgcgtcca ttctttgctt ggttattgat ctggatctcg ggtgaaaaat aagcagagat
    28681 tttttctccc caacctgtct cgggacgctt gttttcatct ttttctgccg cagtagaatc
    28741 accggcaata tggatagtag gcatgttatc tcttctttca taaaggttta taggcaatga
    28801 agcagaacag caagagaaga agacggagca aatttggtcc gtcttcttct ctaaaacgtg
    28861 gataaacgga ttccgttatt tcactatcct gtttttgatt cgttactgtt actattaatc
    28921 aattaggcaa aaaagccaaa gtaattttta gcatttgtat aactaatcgc ttgaactaga
    28981 cttcctaaaa gttgttcatc ttcaggtgct tctcctcgca tgaccatttc gcctaaaaat
    29041 tcacaaagaa cacgacggaa atattcatgt ctagtgtagg acaggaaact tcttgaatct
    29101 gtcagcatgc cgacaaaatt ccccaaagca ctaccatcag caaattgtgt caattgatcg
    29161 cgcataccag ctcgagtatc gttgtaccac catccagaac ctaactgcag ttttccattc
    29221 tgttcttttt ggaaacagcc catcaaagct aaaatcgcag gatagtcatt cggattcaat
    29281 gaataaagga tcgtctttgg caactgatcc gtttcttctg cacggttcaa taatttttgc
    29341 agaggaatag tcaaagaaag atcattcatt ccatcatagc cggtatcggg ccctaatttt
    29401 tccaacattt gtgtattaca gttacgataa gcatggatgt gcagctgcat cgtccaatta
    29461 tgagaatgat agaagtgggt caaatgtatc agtgtttctg tacgataagc atcgatttca
    29521 tctgaagata atagtttgtt agctcgtgct ttttgaaaaa tctcttctaa tactgtttca
    29581 tccgcttctt tatagcgtaa gatgtctaaa gcgtggtcgg aaacacgaca tccatgttga
    29641 tggaagtatt ctatccgctg ccctaagact tctatcagtt cttgataggt ggtgatcgtt
    29701 tggtcagctg cttcttccag tagtgtgacc catgcattaa atccttcttt ttcaatattg
    29761 agtgctttat ctggacggaa tgaaggtaga accttcaaat ctggttcttc atgagcaagc
    29821 aactgatgat agtgcaagtc gtctgcggga tcatctgttg tacaaatcac ttctacattc
    29881 gatttttttg cgatttcccg acggcgaaaa tcaggagctg ccaaaatttc atttgcttgt
    29941 gtccaaattt tctctgcatt ttcttcattt atcaacaagt caataccgaa gaaacgcttc
    30001 aattcaagat gtgaccaact gtaaagcgga tttccgataa tttttggtac ggtttgacac
    30061 caagctaaaa atttttcaaa atcagaagca tttcctgtga ttttttcttc aggcacgccg
    30121 caagctcgca tcaagcgcca tttgtaatga tcgcctccta accaagcttc tgtcagattg
    30181 ctgaaattgt tgttttcgta aatttctttt ggatctaagt gacagtgata atcaataatg
    30241 ggcatgtttt ttgcgtagga atggtaaagc tttttcgccc aatcgtcttt taataaaaaa
    30301 tcatcagata aaaacataaa tcttccttct ttctttttat actgttttat gaaaatcaaa
    30361 gtgttactcc gtttttaaaa atggcaattt ctcgaacgtc attttgttca tttttcgttt
    30421 cttctccact agctacagcg atgatttttt gaacaaacga ttctaagatt acttccattg
    30481 gttgttctaa taagacgcct gcattaaaat ccatccaatg acctttgcgt tcaaaaagag
    30541 ttgtattcgt agataccttg accgttggga catatgagcc aaacggagtc cctcttcctg
    30601 tggtaaacaa gaccaactgg caatcggatg aagcaagagc agaggcagct acaagatcat
    30661 tcccgggagc ttgcaataaa ctaagccctg gttttctgat tttttcgcca tattgtagca
    30721 catcaacgac aggagagctt cctgattttt gcgtgcagcc taaagactta tcttctaatg
    30781 tagtgatccc acctgcttta ttaccaggag atgggttttc gtaaactggt tccccgtaag
    30841 acaagaaata ctgtttgaag tcattgatca agtcaacgat tgagtcaaaa acttcttcat
    30901 tttccgctcg tgccatcaat acttgttctg cgccaaacat ttctggcact tctgttaaga
    30961 tcgtgctgcc tccttgagca atcaagtagt cagaaaatgc accaagtaaa ggattagcag
    31021 ttattcccga tagaccatca gaaccgccgc atttcaaacc gacattcaac ttagagagcg
    31081 ggactgatat gcgctggtca ttttccgccg ctgttaaaag ctcttctaat agagccacac
    31141 cttgttcgat ctcatcgtaa acatcttgag ccactagaaa tttcactcgt tcttcatcat
    31201 attcacctaa aatttttttg aattcaggaa ctgtattgtt ctcacaacct aatccaaata
    31261 ctaaaactcc tccggcattg ggatgattta ctgcgtccgc taaaatttct cgagtatttt
    31321 gatgatcttt tccaagctgc gaacagccat aaggatgctt taaaatcgta atatggtcaa
    31381 actgtcccag atctggatgt ttttccttga actgtttgac gatcagttca gcaatgccat
    31441 tcacacaccc aacggtaggt actaaaaaca aatcattacg aatccctact tttccatttt
    31501 ttcgcaagta accttgaaat gttcggttct caaaaaggta atgacttgga tggacatctt
    31561 tttcatatcg ataatccaat tcaccagaaa gattggtttt tacattatga gtgtgcagcc
    31621 attgaccggc agttacgtct gtcgtcacat gaccgattgg atagccatat ttgatcacgt
    31681 tgtctccagc tttcaaatca cccaatgcaa tcttatgacc ttgcgggata tcttcaagag
    31741 tggtgatcgt ttgctgatca atcgtcagtt gtgtttgttt tggaataggg gttaatgcga
    31801 cgaccacact gtctcgtcga tttaatttca ttgttggttg cagggtttca agcatggacc
    31861 atcgttcctt tcatttcttg taatactgac cggacacctt tttgatcgat ctttgcagct
    31921 atttcttgaa ctgtatctgt cacattcggt atttgagaca aatcttctcc ccaaagcgca
    31981 gcgttttgca ataatcgagg aatagctgtt ccattatcag accaagcatc agtaaattcg
    32041 cttatcgtct tttcatcatc atgtggcttt acttgatcgc ctcgatacat aagaagtagc
    32101 gcagctagtg aaacagtgat taacggtggt acctgatttt gttcttcgat atacttcttg
    32161 aacactggaa gcagacgggt gctgaacttt gaaacactat ttaatgaaat cgcttctaat
    32221 ttgtgatggg caaaaggatt caagaaacgt tctttgattt ggtcagcata aatggctaat
    32281 tcatctttag gtaaagaaag cataggaatc aattctagat tgaataactg atcaacatat
    32341 gcggagaata aaggatcttt cattacttct tctacagttt ccaattccgc caacaaagca
    32401 agagggacca tcgctgtatg cggtccatta agcaaatgca ccttacgttc acgataagga
    32461 gtcatatcat ctgtgatgat gacattcaag ccagcctgtt tgaatggtag ttgattctcc
    32521 aattctttag gcccttcgat cacccaaagc atgaatggtt ctgctttgac catcaattga
    32581 tcttcatagt tatgccgttg attgaaaaca cctgcatctt cgcgaggata acctgggacg
    32641 atgcgatcaa ctaaactaca acagaaaaca ttttcttttt ctaaccactc aacaaaagca
    32701 ggttctaaat cccatttttc tgcgtagcgt aaaatgattt cttttagacg ttcgccgttt
    32761 ctgtcaatca gttcgcaagg aatgatggta aagccagctt tgtttaattt gaaacgtcgg
    32821 tataaaaagg ctgtcagttt gcccgggaag ctctgtgggg gagtatctgt taaattatca
    32881 gtctccacga attggattcc tgcctctgtt gtattggaga cgatataggc caagtcgtca
    32941 ttttctgcta gagatagata agcatcccat tcatcataag gattgatcat ttgttctact
    33001 acggtgataa tctcggaagt atcaacgatt tcgccattgc tgagtccttg taaaatgacc
    33061 gtatataaat tatcttgctg gttcatcata tttccaagac cttgttctaa aggttgaatg
    33121 attgcaacat tacctttaaa caattgttgg ttattcagct gctgaatctg ccaatcaata
    33181 aatccacgca taaaattgcc ttcaccaaac tgaagaactt ttacaggtgc ttcgtttttt
    33241 ttcactaatt cttttgtcag ttttttcata taaacttcct ttctgtgtta tgcacacgtt
    33301 aacattttta tataaaatta cttgtagttt acaagtaatt gatcgactca cgaaggatca
    33361 acaaggtgga gagctcaatt ttagattgtt cgatcgtcct gccttcgatc aaatctagta
    33421 aaagctttgt tccttcttga cacatttctt tcaaaggctt acgtacggtg gtaagcggcg
    33481 gattgagata ggagacgact ggagaatcat cgaacccgat cagagaaatg ttctggggaa
    33541 cacggaggcc agctaaatgt acagctctca atgcaccaat cgctatgtcg tcgttgccgc
    33601 aaaaaaccag agtaggcagg tcagaaagtg ataataggta ttccatgttt tggaggccgc
    33661 tttctaagct gtaatctcct gttaaaaaat aggctggatt gacagggatg ctcgcttttt
    33721 ttagactttt caatacccct ttttcccgtt cttttgtcga acgaaaattt ttctttccgc
    33781 caatataagc gatcttcgta tgtccgcatc caataccgta atctactgcc tgcataacac
    33841 cggccgcatc atcggcagtg acgttgataa ccgctggatc attgatgtga cgattgacaa
    33901 caacgaaagg aaattctttt tctttgagat agtcgatgaa aggctgatca tcatcacttt
    33961 gactcataac gatcagtcca tcgtagcgtt gcaggttgat ttctgttaaa tcaacaacat
    34021 cgatactttc aacagataaa ctgtaatttg tgtctaatac tgaatggatg cctgcaatgg
    34081 aatctgctag gaaatttgat gaagttcctt tatgcaaact tgagaaaaat agtccgatta
    34141 gatatttttt ttgattcact aaaccttttg cactatagtt tggcgaataa ttcatttcct
    34201 tagctagttg tcgtattttt tgttttgttt cattttttat taaactgctg ttattcaaag
    34261 cacgagaaac tgtcgtatga gaaacgccag ctgctttagc gatatctttg atcgttacca
    34321 ttccatcatt ttccttactt tttcactttt tgttaacgca ttcatcatat tacgataact
    34381 acgataagtc aatagatctt tgatatgaaa agattgcaca cgttaaaaat tacttggatt
    34441 tttattttta attatgctat tcttgaaagc ggggaatgct catttaatta gatgagtatc
    34501 aattttacag aaaaatgaaa gccttttatt ttaaaaggag gagaggaaga aaatgaagaa
    34561 aagtacagta ttttataaaa tatttttacc gatgttttta ttaggagccg tacttgtcat
    34621 aggatttagt ttattcattt accagaatac ctatgaatcg atcgaatcga gttatttaac
    34681 agacaaaaag aatttgctca ggcaagttaa aactaacgtt gaatggaaaa ttagaacgat
    34741 tgaatattcg ttttctacgt atggttcgac caaaaatttc tcggacatat tcaagcatcc
    34801 gctgacatat acagattact ccacttattc tgaaatcagg aaagaactaa attttataga
    34861 aacgattgtt atggatgata ataattatga tttagtcagt ttggctggta aatggggagt
    34921 aatcaatgga tcgttgagtc aactgaccga agaggaagtt gaaaagtatc aacagaagta
    34981 cataaataac aaaaataatt tattttggca aaagaaaaac aaaggaatcg aaatggtgat
    35041 ttctttgcca atgtttgaaa aagaaaaata tgcattggga attgctacga tagagaaaca
    35101 tacaatagaa caagttgttg gtgaaagtgg agaagacata ctttctattg aaaacgaagt
    35161 tggcaacctt tttactactc agacagtaaa aaataaagag caaccaactg tattaacgga
    35221 cgtggatcta gattacaatc agctgaaagt gataagagaa aaagataaaa cgtatatagt
    35281 actgaaatca gattataata attggattta cagattagaa gttgactcta gtgcaattgg
    35341 cgcaatgatc cgcaatctga gaatcgggct agttgcagtg tctttaacac tggtaggact
    35401 cattggtctt ctttcctact tattttcgga cagatttgcc cgtccgattt ctcaaataca
    35461 ggaacgtctg aatcttaaat caaaaggatt cagtgggaaa gaactagatt tggtcgctca
    35521 atcagtcagt cggatcatag gagaaaaaga agcgttaagt gcacacttag ttacccaaaa
    35581 gccacagctg gaaacgctat ttgtacttag tttatttaga aatcgagtag aaaggcgaga
    35641 actagatcag cggttgcagc aatttggtta tagttctcaa aatgactgct attatacagc
    35701 tttggttcaa atcgatctgt tagaagatag tcacggtggg gagcgtgatt tgctactttt
    35761 agcgatcaac aacatgatca cggaaattgt gccaaaggaa aatcgaatgc tgccgatcgt
    35821 tttgaatgaa gaaatgcaag ccactattta tcgaatggat aaagatgatg cagaagcaag
    35881 caaaaaagtc atggagtatt gccgactcat tcaaaaacgt gtaaaagaat acttgaattt
    35941 aactatcagt ataggcatca gtaaccggtt cgaaacgctg aatgaaagca agcaatcggt
    36001 tgatcgggca aaagaagccc tgtattatcg tgtaaatact ggtccaagtt caattatttt
    36061 ttatcaggaa atcgttcctg ctgctcatga aaaaacactt attagatatc cgatagaaga
    36121 acaaaatcga ttgtttgaag ccattcgttc tggaaatcag gaagtgaaga atttagtaca
    36181 tgaattgatt gatgcattgt ttgcacaaaa taaaaatcct ttgagtcggg aagtagtttc
    36241 ggtccgcttg atcaatgaac tcgttcaatt aggacagtta ttgggagtag attcaaaaaa
    36301 ctttgataac atgaaacaaa tttatgtaaa agcactgaac aattatcatc ccaaagaact
    36361 agaaaaactt gttttagaac aattagttct gccaatcaca gaatgctctc aagcaatcac
    36421 tgatcatgaa tttaaaaatt tgtcggagaa tattatgcat atcgtctaca cagaatatga
    36481 tcgtgatctg tctttagatg tgatcgctga taggttgcat tataacccta actatttaag
    36541 taatgtattt aaaaaggaaa caggagaaaa atttggtgat tttgttcaaa atcatcgttt
    36601 agaggtagca aaaaaatggt tgaaagagac taacctctcc gtaaaagaga ttgcagaaag
    36661 attgcaatat cgaaatccgc aaaattttat tcgtttcttt aaaaagaagg aatcgattac
    36721 gccgggagaa tatcgaaaaa aatatttgtg aatcaagagg ctgtttttct tgtggactga
    36781 ttcaagcaat aaaagaagtt agaataaccc tagtatttgt atttatggat agttaaattt
    36841 caaggctaag cacgcaaaaa gaactgtgac aaaagtcttg tcacagttct tttttacgaa
    36901 taaatggcgt tcaagagaca ggctatcgac aataaggcat aattttgtga aatatgggaa
    36961 gctatttttc aaaatcgctt cttattgctc ctgtgggtta ctcgtcgcaa tgtttgtgag
    37021 agtttttatc atcgctcaag gctgaacgtc tctttcacaa cctctgatac acggtgttcc
    37081 aggagtagat tcttcgaaaa ataagccgaa atttcacaaa aatttaagaa gcaattttcg
    37141 taaatgcctt cttatttctt gaagctgacc acttctgaca caactaccat tttgcgttca
    37201 gtacataatc accctttgac agaacctacg agtgctcctt tgacaaaata tttctgaaca
    37261 aaaggataaa caatcagcat aggcactgtt gcaataacga taacagccat tttaactgtt
    37321 tgtgctggtg gaatcacatc aacggcacta ctttctgctt gcatcccact tgatacaatg
    37381 acgatttggc gtaaaagaat ctgtatcggc catttagatg aatcgttgat atacaaaata
    37441 gcagtcatat aagtgttcca gtaagtaaca gcataaaaaa gcgagatagt agcaatagac
    37501 ggtaacgcta atggcagcat aattttgaaa aatacaccaa aatctgtgca accatccatt
    37561 tttgctgatt cttccaaact atccggcaag gcttggaaaa agtttctcat aatgatcata
    37621 ttcattgcat taacagccac aggcaggatc atggcccagt aagaattgac cagccctaga
    37681 gaacgaacaa ctaagaacgt tggaatcatc cccccgctga acaacataga aaatacaaca
    37741 agaaagttga cgaaacctcg accaaacaaa tactttctgg aaagaccgta ggccatcagt
    37801 gaagttgcac acatactgac gatcgttccg acacctgtaa caccaatcga aacagcaagt
    37861 gctctaaaaa tggtcggcgt agaaagaatg tagcgatacg cgtctaaaga aaaggtagta
    37921 ggaaaaagga taaacttttt cgcgacgact tcttgtgtag aagcaaaaga tgtagcgatg
    37981 atatttaaaa aaggaacgat acagatcaaa gctagcaaaa ttagaaacgt attgttgaaa
    38041 agtgtaaaac ttctttctcc tatagagact ttctttttca tatagatagg ctcctcctca
    38101 aaataaatta aatgtttctg tttctatatg ttcaatttat catcggtgaa agattacgta
    38161 tataatcatt tcctatgcta agtgtcagat agaaaaaaat agaaggtttg ctatgcgtag
    38221 tttatttgtg aaaaaataca ctttatcgtt ttgtatagca caaaaatcat tgctatgtaa
    38281 gcgtttttac ttacggtaaa aatgattata tacgtaattc agatagttat ctatcatgaa
    38341 gtcataagca gcaaacattc acaaaactaa ggaggggctt atggaaagtg taaagaaaca
    38401 agaaccattt caactgacgc tatcgaaaaa agaagaaaag ctcagaagac gaaaaaaaat
    38461 aattgcagga atcaaaacga ataaattttt atatgtgatg attctgccgg gagtccttta
    38521 tttcttgatt tttaggtatc ttcctatggg gggactcgtt attgcttttc aagattatca
    38581 accattttta ggaataatgg gaagtccttg ggtcggtttc aaacatttca ttcgtttgtt
    38641 tacagaaccg acattcttta cattattaag aaatacgttg atcttgttcg gattaaatat
    38701 cttcgtgttt tttccgatgc caatcatttt gtctttacta ttaaatgaag taacgaacaa
    38761 acgattgaaa aacgggattc aaacgatcat ttacatccct cacttcatgt cttgggtaat
    38821 cattgtttcg attacttatg tatttttgaa tgttgacgga ggggtattga atgaattcct
    38881 tgcaacaatg ggatttgaaa aaatcagttt tctaacatcc cctgaatgga cacgcacagt
    38941 atatatcgga caagtgatct ggaaagagtt gggctggtct acgatcatct acctttcagc
    39001 gataactgca gtcgatacac agttgtatga agctgcagaa atggatggag caggacgctt
    39061 acgcaaaaca tggcatgtta cattgccggc aattcgtcca gtaatcatta ccttgctgat
    39121 tctaaaaatc ggtcagacat tagacttagg gttcgagcat atgtacttgt tattgaattc
    39181 attgaatcga agcgttgcag aaattttcga cacctatatt tatacagctg gattgaagaa
    39241 tggacagtta agtttcagta cagcaatggg attgtttaaa ggggtcgtag gattgtttat
    39301 ggtaatttta gctaataaga ttgccaaaaa gctaggagaa gacggcgttt actaagatag
    39361 aaagagaggg aaagatatgc tgcagtcatt agataaaata aacggaaggc taaatcgtat
    39421 tttacagttg gtttatttga attttctgtg gggcggttta gtcatcgcag gtttgggagt
    39481 ttttactttc ggtcctgcat cgtatgcgat ggttgcagtg attagaaaat ggctgcgctc
    39541 aaaagaaacg tttcctttga cgaaaacgta cttcacatat tttaaagaaa actatcgtga
    39601 aaccttgctg atgagctgga tatatggcgc catcgggatt gttttacttg tggatctttc
    39661 tttcatacac aattggtatc ttaggatcgc tttgtatatt gctgcgttca tatatgtgct
    39721 ctcagcactc tatattttcc caatcatggc tcattatgat tggaaaggat attttttcaa
    39781 aatgaaaatg gcatttttat tcggattctc acatcttcat tactcattag tgttgatatt
    39841 aagtatggta gggatttatc tgatgatcat ccaaacaatg ccaggtgttt taacctttat
    39901 cggtggcagt ctcttctttt ccgcagtcac gtggacagca aattctatat tttgccattt
    39961 ggaatggaag aactcatata cagaaaaaac agaagaaaac aaaaatatta ttaaaacagt
    40021 gaaggagaaa atttatgaaa aaagcaacgc tcgtaaaatt aggtcttagt tttgcaggaa
    40081 ttctagcact tgccgcatgc ggcagcagtt caagtaacag ttcttcagag acagaagatg
    40141 gaaaagctaa aatcacttgg ttaaatattt tgcatcatgc ttcaccgcct acagacacga
    40201 ttgtgaactt gatcgaagaa aaaaccgata cggaactgac attcaactgg attcctgatg
    40261 cttcaaaaga agaaagatta acaactgcat tggcttctga tgaactagga gatatcgtta
    40321 cacttcaaat tgcgatgttg aaaaactctt ctgtccgcaa tgcgttaaaa tcaggcgtat
    40381 tctgggatgt atcagaatat ttaaaagact ataaaaattt aagtcaaatt tctgaagata
    40441 gaatcgaagc tgcgagtatc gacggtgcct tgtacggcgt accgatacaa aaagactacg
    40501 ctcgtgctgg cttagtcatt cgaaaagact ggttggataa tctaggacta gatgttccaa
    40561 ctaccatgga tgagctttat gaagtagcta aacaatttac agaaaacgat cctgatggaa
    40621 atggtgtgga cgacacagtt ggttttggcg atcgtgcgcc tagtgatatt cgttatacca
    40681 gctttaaact tttcacttct tattttggag caccaaatgg ctgggctgta gacgataatg
    40741 gcaaattcac tccagaattt gatacagaag agtatatgaa agctttgaat ttttcaagag
    40801 atctatttga gaatggctat ttggcacaag actttgcagt tacccaaaag actgatcagc
    40861 aagaacaatt tgcacaagga agaactggaa tctacactgg aatggtggat atcaagaatc
    40921 tgaagacgat gggtcaaggt attcaagatg atatggaatt agtgcctgta aacaagatct
    40981 cagatggtga aggcggcggt tatcatgttt ggtcagaagg aaatggtatt ggcggcttgc
    41041 tagcatttcc caaatctcaa gtaaaagacg aagcacaatt gaagaaatta cttcaatttg
    41101 ttgatgatct tttagaagaa gatgtgtata aattgatgac tggcggtatc gaaggaacgc
    41161 attatgaatt gaatgatgat ggttctatcg aatttatcga tatggatctt tggcaacaag
    41221 aggtgcaacc gttatcaagc tctcgtccta gtgaagtgac gttctctttc aaagatacag
    41281 accctgaaaa agaattctct aatcaattga tcaaagaaaa tgaagaattt gctgtaatgg
    41341 atccttctgt gccattggat tcaccgacga acaatgaagt aggatcagaa attgaaaaaa
    41401 tcgtcattga tgctacggtg caatacatca tgggacagct tgacgaagat ggattcaaaa
    41461 aagctgtaga agactggaaa gcacaaggag gcgatcgaat cacacaagag tacgaggaag
    41521 catacaaagc agcggcacag taatatagac gattgggaca aatacttctt ggtatttgtc
    41581 ccaaatccta ttttaatttt taaaggagag caaataatgg aaaactggtc aaagaaatta
    41641 gcaaaaagta tcatggaaag aacacctcgc ttatatgaag aaaagtggta taaaggaaaa
    41701 tggtcttatg actatggcgt cgtacttaaa gggttccaat tactttggga acgaacccaa
    41761 gaaaaaattt attttgattt cataaaagac aatatcgact atttcgtgca agaagatgga
    41821 acgatccgtg gctacagcgt tgaagaatac aatatcgacc atgtaaatac aggaaagctt
    41881 ttctttttat tgtacaaaga aacaggcgaa gaaaaatata aaaaagcagc agaactcctt
    41941 tcccagcagt tggcaaacca tccacgcaca tccgaaggag ctttttggca taaagaaatt
    42001 tatccttatc aaatttggtt ggatggctta tatatgggtt ctccttttta tgctgaattt
    42061 atccagaatt ttagtgaaga aaaagattac caagatgttt tgagacagtt tgaaatcagt
    42121 tataaacatc tattcgatcc aaaaacaaat ttgctgattc atgcatggga tgaaaagaag
    42181 gtccaaccat gggctgatcc aaaaacaggt ctatcccatc atttttggag ccgatcgatt
    42241 ggctggtatt tgatggctgc agcagatacc tatgaattac ttcatgaaga aacagattgt
    42301 tctttgctga aagaaattct agaaaagaca ctggctgcat tacttccata tcaagaagaa
    42361 aacagcggga catggtatca agtaacaaca gaaacaaaac ggaaaggaaa ttatctggaa
    42421 gcttccggca gtagtatgtt tgtttacgca atggctaaag gaatacgttt gggactgctg
    42481 aacaaagaag aatggcttcc acaagtgaag aaatcacatc aaggattact tgatgaattt
    42541 gttctggaaa caaaagaagg ctggctgaac ttgaataaaa actgtcaagt agcagggtta
    42601 ggcggagcag atcagcgaga tggttcatat gcttactaca tcagtgaacc aattatttgt
    42661 aatgatcaaa aaggcgttgg tgcattcttg caagcattga ttgaagtgga ggcattataa
    42721 atatgtatga tattttgaca tttggcgcat caattgatga attgaatact gaagcaatac
    42781 aacaagccat tgatgctgca gcaagtgacg gaggcgggac cgtagttgtt ccagcaggtg
    42841 aatttctaac aggagcttta tttttaaaaa gcaatgtcga acttcattta agcgcaggag
    42901 cggttctgaa attctctgac gatccaaaag attatcctgt tgttcattca cgttgggaag
    42961 gagtccatcg aaaagtttat gcttcctgta tctatgctca aaatgtagag aacatctctg
    43021 tcactggttt cggtacatta gatggaaatg gaaaaaaatg gtggcatact tttagaaatg
    43081 aaccagataa tctcgcttat cctcgtccta aattgatgag tttccataac tgtcatcgaa
    43141 ttactgtgaa agatattaaa ttgatccagt caccaagttg gacgatcaac ccgattcttt
    43201 gcagtaatgc aacgtttgat aacttgacga tcttgaaccc agcggattca ccaaatacag
    43261 acggaattga tccagaatca tgcaaaaatg tgcgtattag taattgccat attgacgtgg
    43321 gagatgactg tattgcaatc aaggcaggga ctgaagatac gtacgaaagg atcgcttgcg
    43381 aaaatatcac gatcacaaat tgcacgatgg tccatggaca tggcggtgtc gtattaggaa
    43441 gtgaaatgag tggtagtatt cgtaatatta ccatttcaaa ttgtatcttc caagaaactg
    43501 atcgaggaat acgattgaaa tctagacgag gtcgaggcgg gatcgttgaa gatattcgag
    43561 tatccaatat agtcatggat aatgtgatgt gtccatttat actgaatctt tattatttct
    43621 gtggtccgcg agggaaagaa ccgtatgtat gggaaaaaaa ggcttatccg atagatgaac
    43681 ggacaccagc attcagaagg atccattttt cgaatatcac ggcaaggaat gtccatgctt
    43741 ctgcaggttt tatttatgga ttagcggaac aattcataca agaaatcaca tttgacaata
    43801 tcgatgtctc gatggcccaa gatgcagttc ccggtgttcc tgctatgatg acaggaatag
    43861 aggaaatgag cagacaagga ttttatattg gctttgcggg taaggtttcc tttaaccaga
    43921 tgtcgattga aaatcacgag ggaccagcat ttctattaga aaatactaaa gaaatcagta
    43981 ttgagaaatt ccaatcaaat caatcagaaa atatggatga actggttgtt cgtaaaaact
    44041 ttgcttatgc agttgaatga ttttttaggt gctccatcta gcagacatac ccctagtgga
    44101 aaacgattat accgagaaaa acaaaacggt tttatgcttg aatactatca attgtactta
    44161 aatgaattgg aaacagtacc agccctctat gcttatccag aaaaagaagg accgtttccg
    44221 ccggtccttt acctgcattc tcacggcgga gatttttcag tcgggaaaag tgaattgatc
    44281 catggtgctc cttacttagc ttctccatct tttgcagaag tactgacagg aatgggatat
    44341 gctgtttggt cgattgatgc ttggggattt gaagaacgcg gaggtatttc tgaaagcgag
    44401 ttgttcaaac aatttttatt aacaggaaaa acgttatggg gaatgcgtat ttatgatgtg
    44461 atcagcttga tcgattattt ggagacaagg gaagacacag atactcaacg gctcgcaacg
    44521 attggtcttt ctatgggagg cttattaagc tggtgggtga cagcattgga ttctcgtgtc
    44581 aaagtttgta ttgatctagc ggcacaggtg gacatcgaaa tacttttgct acatcgccgc
    44641 ctagatcatc atgggtttta ttactatgtg ccaaatctat tgacagctta tacaacgtta
    44701 gcaatccaag aaaaaatcgc tccgcgccct cgtcttagct tagttggaaa aaacgatacg
    44761 atgtgcttgg acgaaggcgt actgaagctg agaaaagggc tggacaaaaa gtatcaatca
    44821 atgggtagtc cagaaaactt ttcttctttt tctttaacag gcggtcatat ggaaacacaa
    44881 gaaatgagaa atatttggaa acaattcata agggagcatt tatgaggatg aaagacaaac
    44941 tgataattgg aaagaatgct atagataccc cgacggattt tgaaactatc caagaaggaa
    45001 tcgattattt ggcaggcctg ccggatagcc atccaaaggt cttgatagta aaagaaggaa
    45061 gatatgatga atatatagaa agcagattat ccaattttaa acttgtggga gcaggaacag
    45121 tagttatctc cggtaatcgt tttgcaaaac aggagtatct tgacggtagc cagttaggga
    45181 ctttccgaag tgctactttt ttcttagaag gatcgaatgt cgtattagaa aatcttcaca
    45241 tcgaaaatac agcaggtcca ggagaaaagg taggacaggc tgttgcttta ttcaattcag
    45301 gagatcgcgt atctttaaaa aactgtcgac tatctggtta tcaggatacc ttatgcacgg
    45361 gtccgttgcc tgatttgcaa aaagatggta ctcctttttg tacaccggct tctgccaatc
    45421 ctgagtattg tcgtcagacc tatgaatatt gctggattga aggaacggtg gatttcatat
    45481 ttggtggggc agatgccgtt tttcatcagt gtcatatcca tagcttagcc agtaaaaatc
    45541 ctggatacat cacagcagca tctacgccga aaaatcaaaa aacagggtat cgttttgaaa
    45601 gctgtacctt gactgcagaa cctgatacta gaaacgtcta tttaggaaga ccgtggcgtc
    45661 cgtatgcaaa tgtcttattt gaagcgtgta agataggtgg gcatgttcac ccaactggtt
    45721 gggataattg ggatgacaag aaaaatgaac agactgtcaa attctctgaa cgtaataaca
    45781 attatgaaac atcgatcaaa agacctgaat ggatacattt agaaaagcag ggggttcaga
    45841 aatgaaaaga aaatgggaac tattgctagg aatggtcggt ggcagtctat ctttgatttt
    45901 ctttggcggg ttagcagtta ctttaagtaa tatgtctgcg tcagagttta aaaaaagtta
    45961 tcagtcgctt gctgtagatc attcaacttt gtctttagaa aatacatttg gattattaca
    46021 ggacatgact ggtctgtttg ccgttgtgtt gtttatttca cttgcttttt tagcagtagc
    46081 attgtttttg actgctaaag gaaaatactt aacaactgcc actggtttgt attttataac
    46141 aggattcata ttgttgattg gcactcagtt tattgcgttt ccttttgcat ttttttattt
    46201 cgcagctggg gcattcagtt tatatcgagt aagaatgaga aaaggagcct gaatcatgca
    46261 gactatcaaa gtgaaaaatc ctattttaag aggattcaat ccagatccta atatattaag
    46321 agtgaaagag cggtattaca ttattgtctc ctcttttgaa tggcttccag gaatccgagt
    46381 atatgagtcg aaaaatttag tcaactggtc acatacaacg gatattttga ccactcaagt
    46441 atctttgcaa ggaaatccta caaatggaag tatatgggcg ccacaaatca gttatgctga
    46501 tggattgttt tatcttgttt acacagatgt caaaagtgca ggccgtccgt ttaaagatgt
    46561 ccacaattat ttgatcactg catctgagat cacaggtcct tggtccgaac caatttattt
    46621 aaatagtaac ggctttgatc cttctttgtt ccatgatctt gaaacgggaa aaaaatggct
    46681 tgtcaatgaa ctatgggatt atcgtctgga cacaccgaat aaatccagcg gtatcgtatt
    46741 acaagaatat gatgcagaga agaagaagct tgatggtccc atctataaaa tatttgcagg
    46801 tacagaatta gcgaaaacgg aggcaccaca tttgtatttt cgtaacgggt attattattt
    46861 gatgacggca gaaggcggta caggaagagg acattcagtt acagtttgcc gagcaaagaa
    46921 tattactggt ccttacgagc ttgatcctgg ttttcctatg ctgacagcta gtgacaaacc
    46981 tgcttctaca ttgcaatgta caggacatgg gagcttagta caaaccccgt caggaagatg
    47041 gtacatgaca tatctttgta ccagaccatt aaacggtgcg gctattttgg gaagagaaac
    47101 cgctattcaa gaagtgtatt ggacgtccga cgattggtta agacttaaag atagccagac
    47161 aactccgatg gaagaaataa tgattgagac aaatgaagag gtacaacaag aaaaagatca
    47221 tcagtttatg gatacatttg aaggagagct aaagaagaac tggaatgcca gacgcatttt
    47281 gccaaatgct gattggtgtg atacaaaatg tagaccaggt tttttacgtc tgatttccgg
    47341 tgaatctctt caatctacct tcgaacatca tttgttagct attcggcaaa cggattttac
    47401 ttttgatgcg gagacagcat ttgaatacat gcctaataat tttaatcaga tggctggact
    47461 ggtactgtac ttaaatgaat ccaattatat ttattgttat gttacttgga atgaggacaa
    47521 gggaaaatgc ctacgtatga tagaatcaga aaacggagta gcacaaatag aagattggac
    47581 gattccactc acagaaaaga agactttttt gaaagtcact gtaaagaaag agacagcaca
    47641 gtttcatttg aaagacgtat caactgaaga atggaagaaa gtaggtccgc aaaaaaacat
    47701 gtgtatactc tcaggagggt ttactggaaa ttttatcggg atagcagtgc atgatctaaa
    47761 taaaaaaaga ggaagttatg ctgattttga gtttttcaag tatgatggaa aagatcatct
    47821 gtaatttaat tctttaataa atgaggttca ctaacttatt ttcactagtt agtgaatttt
    47881 tttgtttgta tatattgtta tgtaaaaaaa gttatcaatc ttatgcatca atgtttttag
    47941 attatttttt gttttttatc tgtcaagata atgcaataaa aagccaacat tgtgaatata
    48001 aaaacaagaa aaaaagagtt ataattttga aaacgtttac tagaagaggt aggaggaatt
    48061 caaatgcttt cacaaaatgc tgttacagca aatacaataa aaaaagaaaa aaaggaattt
    48121 gggatttccg ataagatagg ctacatgttc ggtgatctag gtaactgttt tattttaggt
    48181 ttagtcaata gtttcttgat gatttattat acgaatgttc ttggcgtttc aggggcaatc
    48241 gtaggtacgt tattcttgat ttcgagaatt ttggatgcgt ttgctgatgt gatggttgga
    48301 agattatgtg atgtctcaga gttaacagaa actggccgat ttattccttg gatcagaaaa
    48361 atgaagtatc cattttgctt agtgactgtc attttgtttt tgccattcgt ccaacatctt
    48421 ccaatgacgg tgaagattgc ttatattttt gtttcataca ttgtttatgg gatttttctc
    48481 tcaacaatca atatcccgta tggagcaatg gcagcagcaa ttagctcaaa tcctaatgac
    48541 cgcacctcgt tgtccacgtt ccgaagcatt ggttctgcga ttggcggatc aactacagga
    48601 ttcttcattc cgattttaat gtatacccat aacaagagtg gacaacaagt cgtttcaggg
    48661 aatcatttct tttggatttc aatcggatgt gctgcaatag catttgtcgc atatatgtta
    48721 acttgtaaat tgactactga aagagtaaga gttgtcaaaa acgaaaaagt atctgcttct
    48781 cagttggtaa aaggtttgtt agctaatcga gcactgatta ttttagtcat tgttgacatt
    48841 ttcattgtga tcaatcagat tttagctggg acgaatatga cttatttatt caatgattac
    48901 ttccataata aacaagcaat gtctgttgct cttttattta cttacggaac agtagtagtt
    48961 ttagcaccat ttgctacaaa gctgacaaaa ttatttggta aaaaggaagc aagcgtattt
    49021 gcgttacttg cttcttcatg tatgtacttg ctgatgtatt tccttcatat aacaaatgca
    49081 tgggtatatc tgattctttt atttatcgct actttaggat ctggtttatt caatttgatg
    49141 gtctgggcat tcattactga cgtgattgat tatcatcaat ataagacagg cttaagagaa
    49201 gatggaacag tatatggagt aaattctttt gcgagaaaag taggacaagc atgtgcagga
    49261 gcggtaggcg gatttatgct ggcactcatt ggttaccaat cgtctacaac aggtggagcc
    49321 atccaatcag ttttagtaca agaaaggatt tatacgatgg caaacttgtt accagcattc
    49381 tgcttatttg tatccgcaat cattttgcta gtaggttacc cactgaatcg ttcaaaaact
    49441 gtatttattg gtgaagaatt gaaaaaaatc aatgaaagat agggagaaac gtattgcgga
    49501 caaaaaaagg gattatcaat gctttgaact ttaaaacaaa cgacactcaa caagatgata
    49561 caataatact gcaaaaagca atcgatcaag gtgcgaaaga acacttacct gtatttattc
    49621 caaaaggcat ttatttagtc ggagcccttt ttttaaaaga taagagtcat cttatctttg
    49681 aagaaggtgc agtcctcaag gggagaacag atatcgaagc atttccagaa atcgatacac
    49741 gagtagccgg cgtagaaatg aaatggccag cagcgatttt gaatgttctc tcggcgaaag
    49801 atattcttat agaaggaaaa ggaataatcg acggtcaagg agaccattgg tgggagctgt
    49861 attggggaaa agatcaaaaa agcgggacaa gagctgaata cgatcaaaag ggacttcgtt
    49921 ggattgcgga ttatgctatt aaacgtccac gcgcttgttt actgtatcat gcagaacatg
    49981 ttgttgttcg tgatttgatt tttcagaaat caggtttttg gaacttgcaa atcacttatt
    50041 ctaacgatgt attagtagaa aaagtaatca tccgcaacaa tgatggacca agtacagatg
    50101 ggattgatat tgattcttca acaaatgtgc gtgtctatga atgtgatttg gcctgtggtg
    50161 atgattgtat tgctattaag tctggcagag atggcaatgg tgcaagagtc aatcgaaaat
    50221 catcaagaat cgaggttgct agatgtaaaa tccgttcagg atacggtgta actattggta
    50281 gcgaagttag tgctggagtt agtgacgtat atattcacga tatcgatttt tttcagtcag
    50341 actgtggtat tcgaatgaaa tcttcaaaag aaagaggggg agtgatcgaa aatatcaggg
    50401 tagaaaatct gaatatgatt gatgtacaat ttcctttttc ttggataatg gactggcata
    50461 atgaatacaa tagaaaaaat agcaatgacc ttgctcaaat gccagaaagt tggcaagcag
    50521 tggctgaaga aatacctgaa tcaaagcaaa tgacgaaagt caaagacata cacatcaaaa
    50581 acgtacaggc atgcctttct ccaggttact cacttccttc ccgagctttt gatttagtag
    50641 catttcctga aaagcctata gaagatgtct gcttttctca ttgccaaata actgcaaaag
    50701 aattcgggcg aatcgaagca gtacaaaact tatgtttcaa aagctgtgat ttatctatag
    50761 aaactggcaa cacagctgca aacaatactt ttgacaatcg ttgaaattat aataaggtca
    50821 agcttaaata atattttagc ttgaccttta ttttttttaa tgatatatta aacaacgttg
    50881 tcgcgcttca ttgaaacatt ttatgaaaat tccaaaaaag agttgacaca tgtttttaga
    50941 cgtgataaga taactaagtc gttaaaaaga accacttgcg aagcttgatt ctatcgaaaa
    51001 aaacttcaaa aaagttcttg acaaataaca aacgataagt tatgataaat gagttgctga
    51061 aagatttcga aaaacgaaat cgaaaaaaac ttttaaaaaa gagttgacaa tcgtttgtct
    51121 ctctgatatg atataaaagt tgctacggca gccaaaaatg aatcgggaaa cactctcgat
    51181 gaagtagacc tttgaaaact gaacaaagta agacaaacca aatgtgtagg gcgtcttgat
    51241 tcaattcaag acaa
//
LOCUS       DADVXE010000015        50742 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.015, whole genome shotgun sequence.
ACCESSION   DADVXE010000015 DADVXE010000000
VERSION     DADVXE010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 50742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.015"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            292..663
                     /locus_tag="KB913_000920"
     CDS             292..663
                     /locus_tag="KB913_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBB6819302.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(937..1629)
                     /locus_tag="KB913_000921"
     CDS             complement(937..1629)
                     /locus_tag="KB913_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6819303.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(1632..2417)
                     /locus_tag="KB913_000922"
     CDS             complement(1632..2417)
                     /locus_tag="KB913_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6819304.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            2654..4054
                     /gene="lacG"
                     /locus_tag="KB913_000923"
     CDS             2654..4054
                     /gene="lacG"
                     /locus_tag="KB913_000923"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBB6819305.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            4079..4396
                     /locus_tag="KB913_000924"
     CDS             4079..4396
                     /locus_tag="KB913_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6819306.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            4409..6082
                     /locus_tag="KB913_000925"
     CDS             4409..6082
                     /locus_tag="KB913_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBB6819307.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            6096..7727
                     /locus_tag="KB913_000926"
     CDS             6096..7727
                     /locus_tag="KB913_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBB6819308.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(8218..9783)
                     /gene="guaA"
                     /locus_tag="KB913_000927"
     CDS             complement(8218..9783)
                     /gene="guaA"
                     /locus_tag="KB913_000927"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBB6819309.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(9842..10765)
                     /locus_tag="KB913_000928"
     CDS             complement(9842..10765)
                     /locus_tag="KB913_000928"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBB6819310.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            10961..11566
                     /locus_tag="KB913_000929"
     CDS             10961..11566
                     /locus_tag="KB913_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6819311.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            11874..12890
                     /locus_tag="KB913_000930"
     CDS             11874..12890
                     /locus_tag="KB913_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBB6819312.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13031..14332
                     /locus_tag="KB913_000931"
     CDS             13031..14332
                     /locus_tag="KB913_000931"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBB6819313.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14378..15040
                     /gene="deoC"
                     /locus_tag="KB913_000932"
     CDS             14378..15040
                     /gene="deoC"
                     /locus_tag="KB913_000932"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBB6819314.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            15061..15459
                     /locus_tag="KB913_000933"
     CDS             15061..15459
                     /locus_tag="KB913_000933"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBB6819315.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15525..16607
                     /locus_tag="KB913_000934"
     CDS             15525..16607
                     /locus_tag="KB913_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6819316.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            16819..18381
                     /locus_tag="KB913_000935"
     CDS             16819..18381
                     /locus_tag="KB913_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6819317.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18374..19507
                     /locus_tag="KB913_000936"
     CDS             18374..19507
                     /locus_tag="KB913_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6819318.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19507..20463
                     /locus_tag="KB913_000937"
     CDS             19507..20463
                     /locus_tag="KB913_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6819319.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20562..21728
                     /gene="deoB"
                     /locus_tag="KB913_000938"
     CDS             20562..21728
                     /gene="deoB"
                     /locus_tag="KB913_000938"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBB6819320.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            21752..22570
                     /locus_tag="KB913_000939"
     CDS             21752..22570
                     /locus_tag="KB913_000939"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBB6819321.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22587..23294
                     /gene="deoD"
                     /locus_tag="KB913_000940"
     CDS             22587..23294
                     /gene="deoD"
                     /locus_tag="KB913_000940"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBB6819322.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(23592..24278)
                     /gene="gpmA"
                     /locus_tag="KB913_000941"
     CDS             complement(23592..24278)
                     /gene="gpmA"
                     /locus_tag="KB913_000941"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBB6819323.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(24450..25031)
                     /locus_tag="KB913_000942"
     CDS             complement(24450..25031)
                     /locus_tag="KB913_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6819324.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(25164..25847)
                     /gene="rpiA"
                     /locus_tag="KB913_000943"
     CDS             complement(25164..25847)
                     /gene="rpiA"
                     /locus_tag="KB913_000943"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBB6819325.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            26166..26579
                     /gene="rpsL"
                     /locus_tag="KB913_000944"
     CDS             26166..26579
                     /gene="rpsL"
                     /locus_tag="KB913_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBB6819326.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            26663..27133
                     /gene="rpsG"
                     /locus_tag="KB913_000945"
     CDS             26663..27133
                     /gene="rpsG"
                     /locus_tag="KB913_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBB6819327.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            27227..29314
                     /gene="fusA"
                     /locus_tag="KB913_000946"
     CDS             27227..29314
                     /gene="fusA"
                     /locus_tag="KB913_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBB6819328.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            29486..30673
                     /gene="tuf"
                     /locus_tag="KB913_000947"
     CDS             29486..30673
                     /gene="tuf"
                     /locus_tag="KB913_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBB6819329.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            31080..31388
                     /gene="rpsJ"
                     /locus_tag="KB913_000948"
     CDS             31080..31388
                     /gene="rpsJ"
                     /locus_tag="KB913_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBB6819330.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            31419..32048
                     /gene="rplC"
                     /locus_tag="KB913_000949"
     CDS             31419..32048
                     /gene="rplC"
                     /locus_tag="KB913_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBB6819331.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            32076..32699
                     /gene="rplD"
                     /locus_tag="KB913_000950"
     CDS             32076..32699
                     /gene="rplD"
                     /locus_tag="KB913_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBB6819332.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            32699..32989
                     /gene="rplW"
                     /locus_tag="KB913_000951"
     CDS             32699..32989
                     /gene="rplW"
                     /locus_tag="KB913_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBB6819333.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            33028..33861
                     /gene="rplB"
                     /locus_tag="KB913_000952"
     CDS             33028..33861
                     /gene="rplB"
                     /locus_tag="KB913_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBB6819334.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            33904..34182
                     /gene="rpsS"
                     /locus_tag="KB913_000953"
     CDS             33904..34182
                     /gene="rpsS"
                     /locus_tag="KB913_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBB6819335.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            34205..34552
                     /gene="rplV"
                     /locus_tag="KB913_000954"
     CDS             34205..34552
                     /gene="rplV"
                     /locus_tag="KB913_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBB6819336.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            34566..35222
                     /gene="rpsC"
                     /locus_tag="KB913_000955"
     CDS             34566..35222
                     /gene="rpsC"
                     /locus_tag="KB913_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBB6819337.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            35225..35659
                     /gene="rplP"
                     /locus_tag="KB913_000956"
     CDS             35225..35659
                     /gene="rplP"
                     /locus_tag="KB913_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBB6819338.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            35649..35837
                     /gene="rpmC"
                     /locus_tag="KB913_000957"
     CDS             35649..35837
                     /gene="rpmC"
                     /locus_tag="KB913_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBB6819339.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            35862..36128
                     /gene="rpsQ"
                     /locus_tag="KB913_000958"
     CDS             35862..36128
                     /gene="rpsQ"
                     /locus_tag="KB913_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBB6819340.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            36186..36554
                     /gene="rplN"
                     /locus_tag="KB913_000959"
     CDS             36186..36554
                     /gene="rplN"
                     /locus_tag="KB913_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBB6819341.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            36591..36899
                     /gene="rplX"
                     /locus_tag="KB913_000960"
     CDS             36591..36899
                     /gene="rplX"
                     /locus_tag="KB913_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBB6819342.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            36927..37466
                     /gene="rplE"
                     /locus_tag="KB913_000961"
     CDS             36927..37466
                     /gene="rplE"
                     /locus_tag="KB913_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBB6819343.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            37485..37670
                     /locus_tag="KB913_000962"
     CDS             37485..37670
                     /locus_tag="KB913_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBB6819344.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            37706..38104
                     /gene="rpsH"
                     /locus_tag="KB913_000963"
     CDS             37706..38104
                     /gene="rpsH"
                     /locus_tag="KB913_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBB6819345.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            38136..38672
                     /gene="rplF"
                     /locus_tag="KB913_000964"
     CDS             38136..38672
                     /gene="rplF"
                     /locus_tag="KB913_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBB6819346.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            38833..39189
                     /gene="rplR"
                     /locus_tag="KB913_000965"
     CDS             38833..39189
                     /gene="rplR"
                     /locus_tag="KB913_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBB6819347.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            39210..39710
                     /gene="rpsE"
                     /locus_tag="KB913_000966"
     CDS             39210..39710
                     /gene="rpsE"
                     /locus_tag="KB913_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBB6819348.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            39725..39904
                     /gene="rpmD"
                     /locus_tag="KB913_000967"
     CDS             39725..39904
                     /gene="rpmD"
                     /locus_tag="KB913_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBB6819349.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            39948..40388
                     /gene="rplO"
                     /locus_tag="KB913_000968"
     CDS             39948..40388
                     /gene="rplO"
                     /locus_tag="KB913_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBB6819350.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            40388..41683
                     /gene="secY"
                     /locus_tag="KB913_000969"
     CDS             40388..41683
                     /gene="secY"
                     /locus_tag="KB913_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBB6819351.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            41745..42392
                     /locus_tag="KB913_000970"
     CDS             41745..42392
                     /locus_tag="KB913_000970"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBB6819352.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            42583..42801
                     /gene="infA"
                     /locus_tag="KB913_000971"
     CDS             42583..42801
                     /gene="infA"
                     /locus_tag="KB913_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBB6819353.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            42834..42950
                     /gene="rpmJ"
                     /locus_tag="KB913_000972"
     CDS             42834..42950
                     /gene="rpmJ"
                     /locus_tag="KB913_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBB6819354.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            42968..43333
                     /gene="rpsM"
                     /locus_tag="KB913_000973"
     CDS             42968..43333
                     /gene="rpsM"
                     /locus_tag="KB913_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBB6819355.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            43361..43750
                     /gene="rpsK"
                     /locus_tag="KB913_000974"
     CDS             43361..43750
                     /gene="rpsK"
                     /locus_tag="KB913_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBB6819356.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            43830..44768
                     /locus_tag="KB913_000975"
     CDS             43830..44768
                     /locus_tag="KB913_000975"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBB6819357.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            44796..45176
                     /gene="rplQ"
                     /locus_tag="KB913_000976"
     CDS             44796..45176
                     /gene="rplQ"
                     /locus_tag="KB913_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBB6819358.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            45448..46287
                     /locus_tag="KB913_000977"
     CDS             45448..46287
                     /locus_tag="KB913_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6819359.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            46263..47132
                     /locus_tag="KB913_000978"
     CDS             46263..47132
                     /locus_tag="KB913_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6819360.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            47122..47919
                     /locus_tag="KB913_000979"
     CDS             47122..47919
                     /locus_tag="KB913_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBB6819361.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            48122..48868
                     /gene="truA"
                     /locus_tag="KB913_000980"
     CDS             48122..48868
                     /gene="truA"
                     /locus_tag="KB913_000980"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBB6819362.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            49533..49770
                     /locus_tag="KB913_000981"
                     /pseudo
     CDS             49533..49770
                     /locus_tag="KB913_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(49914..50690)
                     /locus_tag="KB913_000982"
     CDS             complement(49914..50690)
                     /locus_tag="KB913_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6819363.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
BASE COUNT        16066 a         9240 c        11019 g        14417 t
ORIGIN      
        1 ttttatttta acttttgtat atttagtaag tagctacaca cttctatata aattcagaag
       61 ttcttctaga gtttctaaag tttgtttctt aattagctta ttgattctat aatatttttg
      121 atttatatag gaaattaaaa atattataga atcaacactc agagaacggg ttggttttta
      181 atagatttaa taagtactga taatgaaatt tctcctggtt gggaaaacga agttggttac
      241 cctgtagaag aattttttca agattacttt gcggagtatg ccgataggat aatgagagat
      301 tacgtaacag ataaaactca agaagtcatc aatcaatccc agtcattaaa tgaattatct
      361 gataaggcga aagaagaagc agttgccatt atttcttcag ggattagtga ctatattgat
      421 atgagtggtg aaatcaatta tggcgataaa gacaaaattg tacgcatgat aaaagctttt
      481 atcaaaactt ttgatgtgaa ggcagatctt aagtttaatg atacttacct agtaggaaaa
      541 ttaattaata tccttgggac agagaaagat acggaaacgt ttatttcctc tttgtctatg
      601 ttgtttacag ataagcattt ttcaactcag cttggtggag aggaactagt ggaaatcttt
      661 taaccattac gcccagcatt aataaaagta tatcaaaaaa gtactcctga tgatttttaa
      721 gattggtttg agaaataatg tgaaaacact atttttaatg ttaattatag atagagatga
      781 acgcgtcata tggttaaaag aatgaaaaag tcaaagatac actgctatat ttcactaagg
      841 atatagcagt gtatctttca tgtcgtttca ctggcagttt tttataaaag gaggtgtgca
      901 tttcagttgc ttttctttgg tagttagttg aatcgtttaa gaattaacgg atgtggcaga
      961 caggtgctct gtccaaaaac cagtaaaatc tttgatggtt ccatctttat ttagctgtgc
     1021 ctgttcaaat actgttttgt ttttaccgaa tggatcaatt gcaataattg ttccgatccc
     1081 cgcacgtttg gcagcaagta atcctgagta agcatcttcg ataacaagac aatcagccgg
     1141 agctaagctc agtttgtctg ccgctttaag aaaaatatcc ggttgcggtt tcccagggaa
     1201 agagccgtcg tcatagacaa tcttgtccca gtcaaaccag cgggctaaat cgaaaatatc
     1261 aaaataaaaa gcaacattct ctttgacagt agccgtggca atcgttaatg gaatctgttg
     1321 gtcagtcagc tggtcaagag tcgcttcaag cccttttgtc aactgaagct cgttttcatt
     1381 ttgcaagcaa agcatacgat aatagctttc tttttcttct gacaatacgg cgatctcaga
     1441 ggcggtcaaa tgctctgaaa tgaaatgttt caaaatctcc gtattcgtcc gaccatgaat
     1501 attttttaaa atatcctcgt ctgataaacc atcttttgta tgatcatgta tcatatgcag
     1561 ccaagcagct tcatgcagat gagagtccaa aaacattgtt ccgttgaaat caaatataat
     1621 ccctttcata gttacgctcc tatagtggta ttttcggttg aatcagcaat ttgcagatcg
     1681 acatattgtg catagtgctc ttgaacctcc cgcgagatct ggcgatccgt aatgagcaga
     1741 tcgaaatcat gcaaattata aaacacataa aaatcatctc gattgaattt tttattatca
     1801 acgagtagat atttcttacg ggaattattt agagcgatct gctgtgcttc tccttcttcg
     1861 gtactgtaag tagagatcgc ttcgttgtga acgccatttg aactgataaa tgcttttgta
     1921 aactttagtc ttcttaaatt gtcgttggtg atcggtccga caaatgcgcc ggtatttttc
     1981 cggaaatcac cgccaatcag tagaatttct ggtccatctg cttgagcaag aatatcaaaa
     2041 actggataat tatttgtaat gatccgaatt ttcttgttca gtaaatgcgt cgccaatagt
     2101 tcgattgttg tacctggtcc taagaaaatc gtttctccct cgtgaatcaa ggaggctgct
     2161 gtggcagcaa tttctttttt ttcttgaatc tgcagagtgg ctttttcagt gtgagaaagt
     2221 tcttgatcta aagtgtagga aagactttga gcccctccat ggacacgcag cagcttgccc
     2281 gatttttcta attcatctaa atctctgcga acggtcatat cagaaacatc taattgattg
     2341 atgatttcat taacggtaag gattcctttt ttattgacca tttctacgat agtaagcaat
     2401 ctttcttttt tcaacattgt cttcacctct aatttaagga taatctatca tataaacgga
     2461 caacagtcaa tctaattcga acaaaagtaa acatttaggg tggtttttat gtttgttaca
     2521 atagatttta ttgctgtttt ctggttttta tgattatttg tgtttgtttt tgttgacaaa
     2581 tgttttggat gcgtttacaa tgcaatcagt tagaaagagc gaaaactgat tatagatttg
     2641 aggagagatg tacatgctta aattaccaga agattttatt tttggcggag ccacagcagc
     2701 ctatcaggtt gaaggagcca ctaaggaagg tggcaaaggc gctgttgctt gggatgactt
     2761 tttagaggaa caagggcgat tcagtcccga tccggcaagt gatttttatc atcaatatgc
     2821 aaaggacatt gaattgtgtg aacgttttgg tgtaaatggt ctaagattat ccattgcttg
     2881 gagccgcatt tttcctgatg gagctgggaa accaaatcca gaaggaatcg ctttttatca
     2941 tcgtgtgttc gaagaatgta agaaaagaaa cgtaacgccg tttgtgacgt tgcatcattt
     3001 tgatacccct aaacgtttgt ttgaccatgg agattttttg aatcgagaaa caatagaagc
     3061 atttgtttcc tatgccattt tttgttttca tgaattcaaa gaagtcaagg tgtggagtac
     3121 ctttaatgaa atctatccag ttgcaaccaa tcaatatttg ttaggtgttt tcccaccagg
     3181 aatcaaatat gattttacaa agatcgtcgc ctgtcttcat aatatgatgg ttgctcatgc
     3241 ccgtgtagtg aactatttca aagaaaacga acttccgggt gaaattggtg tagttcactc
     3301 attagagacg aaatatgcgg caacagacgc gccggaagat aagcatgctg cctttttaga
     3361 cgatgcattg tcgatccgtt tcttattaga tgctacctat ttaggctatt attcaactga
     3421 aaccttgact gctcttgatg agatatgtga agcaaatcag gccagctatc attttcctga
     3481 agaagatttc gttgaattga aaaaagcatc cacgcgtaat gactacttag ggatcaatca
     3541 ctaccaatgc cattttgtca aagcttacga tggagaaaat gcaatccatc ataacggtac
     3601 gggtgaaaaa gggacctctg tttataaagt gaagggaatc ggagaacgta tttataaaga
     3661 aggaattcct cgaactgatt gggactggct gatttatcca gaaggtctat atgacttgtt
     3721 gctgcgaatt aaaagcgatt acccacatta caacaaaatc tatatcactg agaacgggat
     3781 ggggtataaa gatcagtttg aagatggcat tattatggat cagccgagaa tcgactattt
     3841 gagagtctat ttggaatcct taagcaaggc gataacagcc ggggtaaatg tgaaggggta
     3901 ttttttgtgg tcgcttatgg atcttttctc atggacaaat gggtataaca aaaggtatgg
     3961 cttgttttat gttgattttg aaacccagaa gcgttaccca aaagaatcag cttactggta
     4021 caagttggtc agtgaaacca aaacgattat ttaataagtg ataatggagg aagaaaagat
     4081 gaataaagag gaattacaaa tgcttggttt tgagatcgtt gcatattcag gcgacgctcg
     4141 cagtacatta ttgaaattat tgaaagaagt aagacaagga aactttgaac atgttgattc
     4201 ggcgttgaaa gaagccgacg aaaatttaac ccttgcacat aattcgcaaa caaaaatttt
     4261 agcggaagaa gcatctggga aagagatgga gatgggattc atttttatcc atgggcagga
     4321 tcatttaatg accactttat tgctgagaga tctgattcaa gactttattg tactgtacag
     4381 acagaatcaa ggataggaga agaacgctat ggatggaatc attaaacaaa tcgaaaaagg
     4441 gaaaccattt tttgaaaaaa tctcacgtaa tagttattta ggagccgttc gtgacggatt
     4501 tttaacagcg atgccagcta ttttattttc aagcattttc attttgattg ctgcggttcc
     4561 tgagattttt ggttaccaat ggcctgaatc tgtctccaca tggctatgga aagtctataa
     4621 ttattcgatg ggtgttgtag ggttactcgt ttcagcaacc actgctcgct gcttggctga
     4681 ttcgatgaat cgtcgcttac cgaaaaacaa agtaatcaac accacctctg tgatgctggc
     4741 ctctgtggta agtttcctgt tgttaagcgt ctctccgatt gaaggtggat tttcaacgga
     4801 atatatgggg acaaagggac tactggcttc ctttgtcgct gcatttttaa cagttaattt
     4861 atataagttt tgtgtgctga aagatattac cattaaaatg cctaaagaag ttcctggaac
     4921 gatttcgcaa accttccgag atatttttcc tttctctttt tcagtatttg cggccgtttt
     4981 aattgattta ggcattcgac aaatcttcca aatctcattt gcagaagcaa tcattacggt
     5041 gctgcagccg ctatttacag cagctgacgg gtacttagga atcgctatta tctggggagc
     5101 gatggcgctg ttttggtttg tcggtgttca tggaccgtcg atcgtggagc cggcaattgc
     5161 ggcaattatc tatgccaatg tggaaaccaa tctgcaattg ttcaattccg gtgaacaagc
     5221 ttctaaagta ctgacggtgg gtttagggaa ttttgtagga actatgggag gaactggggc
     5281 aacattggtt gttcctttta tcttcctact ctttgctaag tctaagcagt tgaaggcagt
     5341 tgggaaagct tcctttattc cagtaagttt cgctgtcaac gaaccattgc tatttgcggc
     5401 acccatgatt ttgaaccctt atttttttat tccatttttg ttaacacctg ttgtaaacgt
     5461 ttgcctgttc aagttttttg tcgatgtatt gggcatgaac agctttatgt acgttttgcc
     5521 ttgggcaact ccagcaccga tcggtttggt tctaggaacg ggcatgggta tcttagcttt
     5581 tgttctagca gcggttctaa tcgtcgttga cttcctgatc tatctaccat tttgcaaagc
     5641 atacgatgct gtcttagtag agaaagaagc acaaaaagca gaggtgatcg caaccgagga
     5701 aggtgcttct gccgatgtac gtgaggaagt acctgtggca gcgagtcaag ttatcagcga
     5761 tgcaaataaa gaaatcaatg tgttggtact ttgtgctggc gcagggacaa gtgggatgtt
     5821 agctaatgct ttaaaaaaag gtgcatctga atcgaaagca ccgatcagtg caatggcggg
     5881 tgcttatggt tctcattacg aaatgctgca ggattttgat atggtggtct tagcaccgca
     5941 agtcaattct tactatgatg atatcaaaga agacaccgat cgcttaggaa tcaagctggt
     6001 tgcgacaaaa ggagcagaat atatcggatt aacgagagat cctgaaaaag ctgttcagtt
     6061 tattctgaac caatttcaat aaaggaggag ccataatgaa aatgggaatt tggttgcgta
     6121 aagctgtttt atttgcagct gtgttagggg ctttgggggc tgtttcaaaa actgttgaag
     6181 catctgccag cgaatttatt cgcggagcag atatttcgat cctgtcagat atggaaaaat
     6241 ctggtgcaaa atattatgaa gacgatattt caaaagatgc cttagagatt ttaaaaaata
     6301 atggtgtcaa ctatgttcga ctgcgtttgt ggcaggatcc ttataatagt aatggagaaa
     6361 gttatggagc agggacaaat gatctggaaa cgacgattga ccttgcaaaa cgagcaaaaa
     6421 atctgggact taaggtgctg ctggattttc actacagtga tttttgggtt gatcctggga
     6481 aacagaatct tcctaaagca tggcaaggtc tgacctttga agaaatgaat acggcattgt
     6541 acgactatac aaagaacgtt ctgtcggaaa tgaagcagct ggacgtttat cctgatatgg
     6601 ttcagatcgg caatgaactg aatagcggaa tgctctggcc ttatggcaag tcttggggag
     6661 aaggcggggg agaatttgat cgattggctg cttttttgaa gtctggtatc caagctgttc
     6721 gagacactca acctaaaaca actccagtaa tgctccactt agctgatggt ggcgatacag
     6781 gagcatttac ttggtggttt gatgaaatca cgagtcgagg tgtgtcattt gatttaattg
     6841 gagtgtcgta ttatccgtat tggcacggtt caatgaatga acttcaaacc aatatgaatg
     6901 cgatcagcca acggtatggt aaagaagtga tcgtagttga aacagcttat gggcatacaa
     6961 cagcgaatgc cgatactatg ccaaatgctt ttggtgaagc cgaagcagct gcggggggat
     7021 atgaaccaac accgacagga caagcagagt atttgctgga tcttgccgat cggattcagg
     7081 cagtaccgaa taatcgcggg gcgggcttct tctattggga acctctttgg tacaacggaa
     7141 atgtgagttg ggcaacacaa gcaggtatga attatctcag tgttcaatcc actatgggaa
     7201 acgaatggga caaccaagcg atgtttgatt ttgctggaaa cgccttgcca agcttgcgtg
     7261 cgtttaaaca agcaggggcg caaataaatc tagttaaaaa tgcaagtttc gaaagcgatg
     7321 gaccaacgac cagtccttcc aattggcaaa cctggtttca acaaggaacc gctaagggta
     7381 cgatcaaaac ggaagcgggc actttttttg gggactacaa actaactttt tggcaggatc
     7441 aagcatacga ggcatcagct tatcaaaatg ttagtggcat aagcaaagga acttacacat
     7501 tgagtgccta tgtaatgtct gggggagagt ttgatactaa tcagttatat atcaaaaatt
     7561 atggtggagc ggaactaaat actgcggttg ttaaaacaag tgaatggaca aaaattacaa
     7621 tcaaagacat tccaattaca acaggtgttt gtgaaattgg ggtttatagc aaggcttcag
     7681 gaaatgcttg gacgaacgtt gattttgttt cattggtgaa acaatagact gcggatcgtt
     7741 tcgattcaag atcggaggtt cccttcagcc acatcgttag cgtagaaggc aggaatcgaa
     7801 cctgcacctc gcctttgcca aaaataacca gaaacgattt ccagtcattt ttaccaaaac
     7861 gagtaaagca ccagacttca tctacacttt gtattatgct aaagagagtt caacgatttc
     7921 gtaagaagca atgaaaaaat tgcaaaaagt tgtgcagata acataaagtt tgtttaagaa
     7981 agggtaacct tagaattccg tcgtgaatat gatttgagca cttagatgga tagaaaaaag
     8041 ttctcggaaa acagttcgtt tttcgagaac ttctttttat gataagaatg aaacaaatta
     8101 acttatatta tagtctcttt tggtagggaa ccatcttatt tttaatgaaa atcaagcatt
     8161 ttagctattg aagaatgttg atttataggg attccccctc catattatgt tggctcttta
     8221 ttcccactcc actgttgctg gtggtttaga agtgatgtca tacacgatac ggttgacgtg
     8281 ggctacttcg tttacgatac gtacagagat tttttgcaag acttcccatg ggatacgggc
     8341 aaagtcagcg gtcattccgt cgattgaagt tacagcacgg ataccgactg tgtagtcgta
     8401 agtacgtccg tcacccataa caccgacaga gcggatccct ggaagaacag tgaaatattg
     8461 ccagatatca cggtcaagtc cagcagctgc gatttcttca cgcaagatag catcagattc
     8521 gcgtacgatt tctagcttgt cttcagtgat ttcgccaaga acacgaatac caagaccagg
     8581 accagggaat ggctgacgcc aaacgattga atcaggcatg cctaactgag tccctaattc
     8641 acggacttcg tctttgaata atgtgtttaa tggttcgatc aattcaaatt gcatatcttc
     8701 tggcagtcca cctacattat ggtgagattt gatcgtctgt gctgtttctg taccagattc
     8761 gataacgtca gtatacaacg ttccttgtgc taggaaagag acgccttctt caccagcaag
     8821 ttttgttgct tcgtcatcaa aaacatatac gaattcattc ccaatgattt tacgtttttg
     8881 ttctgggtca gatacacctt tcaacttgtc taagaagcga tctcttgcat tgactttgat
     8941 gatgttcaag ccgaattttc cgcctagact ttccattact tgttccgctt cgcctttgcg
     9001 tagcagaccg tggtcaacaa agatagatgt caattggtca ccgatcgctt tttgtaaaag
     9061 aaccccaacg acactagaat caacgccacc tgaaagacca agcaagactt ttttgtcacc
     9121 aacttgttca cggatttttt ctacttgcat atcgataaag ttatccattg tccagttacc
     9181 ttcacagtga caaacatcaa aggcaaagtg gcgcagcaat tcgattccgt attcggaatg
     9241 acgtacttct gcatggaatt ggataccata aaaattacgt gttgtgtctt ggatagaagc
     9301 aatcggacaa tctttgcttg ttccgactgt ttcaaagcct tcaggaactt tagttaccaa
     9361 gtcaccatgg ctcatccata ctgtttgttg ttttggtgtt tctttaaaca agacagcttg
     9421 atcgcttgtt acttctaaca aggctttccc atattcgcgg tttttagcag gctctacgga
     9481 accgccaagt ttgtacgtga tcaattgcat accatagcaa atccctaata caggaatacc
     9541 taaattgaag atctcaggat cgatcccaaa tgcattctca tcatatacac tgtttggtcc
     9601 gccagaaaga atgattccct ttggattcat cgcttttact tcttctgcag taatgcggtg
     9661 gctcaataat tcggaaaaga ctccaagatc acgaatacgt cttgtgatca attggttata
     9721 ctgactaccg tagtctaata cgataatctt ttcaacgttc gtcatatcgg caacgtttgt
     9781 caaatttatt acccctatcc ctttaaattt tatctcaaaa tagtcaaact attttaaaat
     9841 gctaatattt tcgcatgaaa atcgaatcga tgatatgatt ttcagtttta tggagaatta
     9901 tatcggctct tcctcgtgta ggcaagatat attcctgtaa atttttcaaa ttcacatttt
     9961 tccatacatc ttttgccatt ttaaaggctt cttcacgatc tccgatagca aaacgataat
    10021 aataattctc tggattttgg aaagccgtat ccagtaacgc accaaaacga tccaaatacc
    10081 atttttcgat cagcacggga tcggcatcga catagacaga aaaatcaaaa aagtcgctga
    10141 cgtagatttg ctgattcgca ggtaattgaa gcgtattgat cccctcaacg atcaagatat
    10201 caggctgctg gatcaattcg tacttgtctg gaatgatatc atacacatca tgtgagtaaa
    10261 caggtacttt tatctcttcc tgaccagatt ttacacggtt caagaaatcg atcagcatct
    10321 ccatatcata actttcagga aatcctttac ggtccatgat tccacgctct tttaatatac
    10381 gatttggata aagaaatccg tcagtcgtga tcagctgaac gtttcttcgt ttgaaggtac
    10441 gagacaaaat cgtctgcagc agtctggctg ttgtactttt tccaacggct acacttccgg
    10501 cgatcccgat aataaaaggc ggtacttcta cgtatttatg aagaaataaa cctttactca
    10561 agaacaaaga ttcaaattct ttcatataaa gataaatcag atgagcaaga ggtacataga
    10621 tatctcgaac atcctgcatg gaaatgcggt cattcaaact tttgatatta tctagttcat
    10681 cttgtgtcaa aggtgcttgc ccattacgat aaaattctcg ccattcttct cttgccacac
    10741 ggtagtagtt cattggatca ttcatattag cctcctgcgt tctcccatca atggaactat
    10801 tttaacacaa aataaacgca aaccccacca cttaagagag attgccgatc tttttgtata
    10861 atctttataa tagaaagaaa cggagtctta ttcttgactt gcgcacggat acataaaagg
    10921 atagactgtt gtcatgaaag aaatgagaag gatggaagac atgacaaatc attactattc
    10981 tgaacgccca gatacggcgc acgattttga acaatgggct tttgagttaa aaggcagaac
    11041 ctttcaattt gtaacagatt ctggtgtatt ttcacgtgaa acagtggatt atggttcacg
    11101 tgtcctgatt gatgctttcg attgggaaga gttacctgat gaaggaaaga tcttagatgt
    11161 gggatgcggg tatggaccga ttgggttagc tttggcattt gcgacacagc ggtttgttga
    11221 aatggtcgac attaatgaac gagcggtaag tctagcgcaa ggaaacgcaa agcgtaacca
    11281 aatcgaacat gttgatatcc atcaatcgaa tatctatgaa gcagttcatg aagaaaccta
    11341 tgcagctatc gtaagcaatc cgccgatccg tgctggaaaa aaagttgtac atgaaatttt
    11401 gacaggcgca tatcctcggt tgaagaaggg cggtacactg acaattgtga tccagaagaa
    11461 acaaggagcg ccgagtgcgc aaaagaaaat ggaagaaaca tttggtaatg cagaaatcgt
    11521 cacaaaagat aaaggatatt atatcatcaa aagtgtgaaa gaataactag ctgaaaaata
    11581 gtggagcgac gaaagagtgg aactgggcgt gcatgtacgg gtacgtatca gttctttttt
    11641 tgttgagaag tttttaaaaa caaagaacta ttttttcttc aaaaagaaat agtaggaaca
    11701 gagtcgttgt tttttacgat aaaataaata agatacagaa cttgtataga aggctgccaa
    11761 gtcggtagat aaaggaggtt tttatcaaaa aacatacttt ccttttttct ctattctttt
    11821 cttgggggtt ttggtacact gatagggaat ttagatagaa gggagccaat aggatgaagc
    11881 tgaccatcag agatatcgca gaaatggcag gcgtatcagt aacaactgtc tcacagattt
    11941 tgaataacaa aggaagcaga tttagtgata agacaagaaa aaaagtgttg tcgatcgtga
    12001 atgaacatca ttataagccc gattatttcg cttcaaatgt gatcaatcga cattcaaaga
    12061 ccatcggaat gatcgtccct gatgtcactg atttcttctt ctccaaactg atcgaaggtg
    12121 tagagagcta tttgaatcct ttgggctatg tgatcatgtt atgcaattct cgtcatagcc
    12181 aagaaaatga gatcaagtat ttacaagagc tttcccaccg ctcagtggac ggaatcttgc
    12241 tggccacacc aaatatttta cctgagaaat atgcattaga cagcggtttt tatcaaaaaa
    12301 tgccaatcat tttaatcgat cgcggattga atcgtcggga taacggacgg cttatcgtaa
    12361 aggaatatga gggcgcctat caagctgttt cgctgtttat tgaaaatggc catacgaaga
    12421 tcggcatgct gaaggaaacc actggatact atcaattaga agaacgtttc aacggatatc
    12481 gtcatgcgct gaaagatcat ggcctgcctt ttaatgggaa atttgttgaa catggagagt
    12541 tgactgtcca aggtggatat actgcatcaa aaaaattact caaacataaa gatatcacgg
    12601 ctattttttg cgggaatgat gccatggcga tcggatgcta tcaggcgatc gatgaattgg
    12661 gcaaaaaaat cccagaagat atctcagtca taggattcga tggattaaag ctgtcagaat
    12721 acatgattcc gcaattgacg acagtgcagc agccaagttt tgatattgga ttttatgctg
    12781 cacgtttcct gatcgatacg atcgaatttc ctcaaagaaa agttccgaac aaagtgttcg
    12841 aaacaaaatt aattattcgt gagagcgtaa aagtattgac aaagggctaa ctcggcggta
    12901 tattgcttat gtaagcattt acaaaggcta gttagtgctt tttttatttt tagtaaacca
    12961 gtttactaaa gtggtttacc tttcctaaaa ataatgtata ataccgaatg aagacaagga
    13021 ggatcaggca atgcgaatgg tggatctgat tgaaaaaaag agggatggaa acgagctgtc
    13081 gaaagaggaa atcgagtaca tcgtcacgaa ctatacgaat ggaaagattc cagattatca
    13141 agtcagtgca ttattgatgg caatttttta tcaagacatg acaaatgaag aaatcacgaa
    13201 cttaacattg gcgattgcta attctggtga tgtcatcgat ttgagttctc ttgaaggaat
    13261 aaaggtagat aagcattcga caggtggcgt tggtgacacg accacattga ttttagcccc
    13321 cctagtagct agtgtcggag tgacagtggc taaaatgtct ggacgcggtc taggttacac
    13381 aggtggtaca ctagacaagc tagaagcaat tcccggattt cagatcgagc tttcggatga
    13441 agaatttgta cgcattgtta atgaaagtaa agtagcggta attggtcaat caggaaactt
    13501 ggcaccggcg gacaaaaaat tgtatgcctt gcgtgacgtc acagcgaccg ttgattctct
    13561 tccgctgatt gccagttcga ttatgagtaa aaaaatcgcg gcaggagcag atgcaatcgt
    13621 tttggatgtg accactggag acggtgcttt catgaagaac atcgaagatg caagacgtct
    13681 ggcaaagacc atgacgagca ttgggaaact ggctaaccga gaaacagtgg cggttatctc
    13741 agatatgtca gaacctcttg gcgaagctat cggaaatagt ctagaagttg tcgaggcaat
    13801 cgaaacatta caaggaaatg gtccagaaga tctagtagaa atgtgctacg ccttaggaag
    13861 ccaaatggtt gttcttgctg gcaaagctaa gacaaccgat gaagcaagaa cgttgcttca
    13921 agaagctctg gaatcaggta aagcgttagc aaaattcaaa gaaatgatcc aaaatcaagg
    13981 gggagaccca gcgatcgtgg aacatccaga acgaattttg actgcacgct acacaatgga
    14041 gcttcctgct aaacaaagcg gagttgtgtc aaaaatcgtg gcaaatgaat taggaattgc
    14101 tgcaatgatg ctaggtgctg ggcgtaaaac caaagaagaa gatattgatc acgctgttgg
    14161 attgaaactg cataaaaaaa ttggtgacac tgtgacaaaa ggtgagtcac tattgacgat
    14221 ctatagtaac gacgaagaaa tcacttctgt cattgaatta ttatataaaa atattgaaat
    14281 tggtgaatcg gcaatgaagc caacgttgat tcatgacatc atcacagaat aaaggaaaaa
    14341 agcggacttt accgttttaa agaaaagggg aaaagaaatg gaactaaacc gaatgatcga
    14401 ccatactatt ttgaaagcag acgcatctaa agaagctgtg atgcaaatta tcgaagaagc
    14461 aaaaaaatac catttttatt ctgtctgcat caatccagca tgggttgcgc tagcgaaaga
    14521 acaattacaa ggtgagccag tagccgtatg tacagtaatc gggtttcctc taggagcaaa
    14581 cacacccgag acaaaagcat ttgaaacaac agatgccatc aataacggtg cagatgaagt
    14641 cgatatggtc atcaatatcg gtgctttgaa atcaaaggat gatcaacaag tccaaaaaga
    14701 tatcgaagca gttgttgaag cagcaaaaga tcgtgcgctt gtcaaagtta ttattgaaac
    14761 atcgttatta gatagagaag aaatcatccg agcttgcgaa atagcaaaag ctgcaggcgc
    14821 tgattttgtc aaaacatcaa ctggtttctc aacaggcgga gcaaaggtag aggatgtccg
    14881 tttgatgcgt gaaactgtag gaccagaaat gggtgtcaaa gcttccggcg gtatccataa
    14941 cgaagaagaa gcaatggcaa tgatcgaagc tggtgctaca agaatcggaa caagcgcagg
    15001 agtagcaatc gtatctggtt caactggtga aggctattaa ttttttcaaa ggagaagctc
    15061 atggcagaac tcaaacaaga atggatcaac acagctattg aagcgttaga taaagcctat
    15121 gttccttatt cccattttcc ggtaggcgct tgtctcgtaa cggaatcagg caagatttat
    15181 caaggcatca acattgagaa tgcatcattt ggattaacga attgtgccga gcgcacagct
    15241 tttttcaaag cagtatctga aggagaaaaa acatttacgc atctagtcgt agcggggcac
    15301 acccccgatc ctatctctcc ttgtggtgca tgtcgacaag taatggcaga attctgttcc
    15361 cctgatatgc cggttacgct agtaggagac aatggtgtga cgaaggcaac gaccgttcgt
    15421 gcactgctgc cttatgcatt tactgaaaaa gatctataac tcatgttcat tcagtcagct
    15481 gactgttgaa aaataaaaca attattttag gaggctttac agaaatgaaa aaagcaaaat
    15541 tatttggttt aggtgctgtc gcactagcag cagggttatt tttaggtgca tgcggcaaca
    15601 acggctctac tgattcatcc ggtggcaaaa gctcatcaga cacaacaact gcagcattga
    15661 tcacagacac aggtggtgta gacgaccgtt cattcaacca gtcagcttgg gaaggactag
    15721 aaaaatgggg gaaagatcaa ggactttcac gaggaaatga tggcttccaa tatttccaat
    15781 cttcaaatga atcagattac atcccaaata ttgaccaagc attgaatgct ggattcaaaa
    15841 cgatttttgg tattggttat aaactaaaac cagcgatcca agaacaagca acaaacaata
    15901 caggtacgaa ctttgttatt atcgatgatg tcatcgatgg attagataac gttgtatctg
    15961 caactttcaa agacaacgaa gcttcttatc ttgcaggtgt tgcagcagct tatacgactg
    16021 aaacaaacgt agtcggcttt atcggcggtg taaaaggtga agtaatcgat cgttttgatg
    16081 ctggattcaa agccggtgtt gatgcaggtg cgaaagaatt aggaaaagaa atcaaagtat
    16141 tgaatcaata tgctggtgac ttctctgctc cagataaagg acgttcaatt gctcaaggta
    16201 tgtatgcaca aaacgcagat atcatcttcc atgcttcagg cggtacaggt aacggtgtat
    16261 tccaagaagc aaaatcattg aacgaatcag gcgacaaaaa agtttgggtt atcggtgttg
    16321 accgcgacca atcagacgaa ggcgaataca cattaaacgg cgaaaagaaa aacttcacat
    16381 tgacatctac actgaaagca gttggaacag tagtagaaga tttggcacaa aaatcagcgg
    16441 acggtaaatt ccctggcggc gaacacactg tttatggatt gaaagaagac ggtgttggtc
    16501 taacagaagg acaactttct gacgaagcga aaaaagcagt tgatgaagca aaagaaaaaa
    16561 tcatttcagg tgacgtaaaa gttccagaaa ctcctgaaga aaactaaaac catttctata
    16621 gccttgttag acacatgttt gacaaggcta tggtttgatt agaacaagaa ttgttcattt
    16681 atccaagctg ccttgtgaca gtttggataa gggaacaact ccctgaagta atgtttgttt
    16741 caaaagaaga acgctcacta agcgtgaatc ttagtcaatc gttgccctag atagaaatcg
    16801 ttaggatgtg aaaaaaaggt ggttcaagaa aatattgtca tagaaatgca gaatattacc
    16861 aaagaatttg gaacattcaa ggcaaatgac aacatcaatt tacaagtaaa ggcaggagaa
    16921 attcatgcgt tgcttggaga aaacggtgct ggcaaatcta cattgatgaa cgtgctttcc
    16981 ggattattag agccgacatc agggaaaatt ttgatgcgtg ggaaagaagt aaagatcaca
    17041 agtccgacca aagccaacca attagggatt gggatggtcc atcagcactt tatgcttgtt
    17101 gatgccttta ctgtaacaga aaacatcgtg ttgggaagcg agcctagtcg cgcagggatg
    17161 cttgaccata aaaaagcacg aaaagagatc caaaaagttt ctgaacagta tggattgtca
    17221 gtcaacccag atgcttacgt tcgtgatatt tcagttggaa tggaacaacg ggtagaaatt
    17281 ttaaaaacac tttaccgagg agcagatgta ctgatttttg atgagccgac agctgtattg
    17341 acccctcaag aaattgatga attaatcgtg atcatgaagg aattagtcaa agaaggcaag
    17401 tcgatcattt tgattacgca taagttagat gaaatcaaag cagtagctga ccgctgtaca
    17461 gttatccgcc gtggaaaagg aatcggtaca gtcaacgtta aagacgtaac ctcacaacaa
    17521 ttagccgata tgatggttgg aagaacggtt tcattcaaaa cgatgaaaaa agaagcgaag
    17581 cctcaagaag tcgttttgtc tattgaaaat ctagtggtga aagaaaatcg tggattagaa
    17641 gccgtgaaaa acttgaactt agaggttcgt gctggcgaag tacttggtat cgctggaatc
    17701 gatggaaacg ggcagtcgga gttgatccaa gctttgactg gtttgcgaaa ggcagaaagc
    17761 ggacatatca agctaaaagg ggaagacatc actaataaaa aaccccgaaa aatcactgaa
    17821 catggtgtag gacacgtgcc agaagaccgt cataaatacg ggttagtcct agatatgaca
    17881 ttatctgaaa atatcgcact acaaacctat catcaaaaac cttacagtaa aaacggcatg
    17941 ctgaattatt cagtaatgaa tgaacatgcc agagaattga tcgaagaata tgatgttcga
    18001 acaacgaatg aacttgttcc cgcaaaagct ttatcaggcg gaaatcagca aaaagcaatt
    18061 atcgctcgtg aagtcgaccg agatcctgat ctgttgattg ttgcaaatcc aactcgtgga
    18121 ctggatgtag gtgcgatcga atttattcat aaacgtctga tcgaacaaag ggacaaatac
    18181 aaagcagtgt tactgatcag tttcgaatta gaagaaattt taaatgtttc ggatcgtatt
    18241 gctgttatcc atgaaggaga aattgtcggt atcgttgatc cgaaagaaac atctgaaaat
    18301 gaattaggtc tattgatggc gggctatacc ttagaagaag cacgaaaaga gttagaaaag
    18361 ggggctggcg cacatgaatg atcgcagcga aaaattccgt aatttattag tgcctgtact
    18421 ttcagttgtt ttaggattga tcttaggcgc gatattgatg gctgcttttg gttttcagcc
    18481 catccaaggt tattcttcta tgctagatgc agcccttggt tcgcaaagag ggataggtga
    18541 aacgttaagg caagcaacgc cgttgatttt tacagcatta ggtttttctg tagctaactc
    18601 agctgggttt ttcaatattg ggctttctgg acaagcactt tgcgggtgga tcgtcagtgt
    18661 ctgggtggca cttgcgtttc cagatctgcc aaaagttgtt ttgcttccgt tatgcgtgat
    18721 cttaggtgcc ttagctggtg cgatggcagc ggctgttcca ggtttacttc gagcattttt
    18781 tggaacaagt gaagtgatcg taacaatcat gatgaactat atcttattat acgtaagcac
    18841 atttgcttta catgaagtga tgcctgaaag ctatcgctca agtttggact cttccaatat
    18901 gatcagtcaa aatgcctcac tgcggttacc atggttaaca caagcttttg gcggctctcg
    18961 cgtaaactca ggattatttt tagcaatcat cgcgcttatt ttcgtttggc tgctgatgaa
    19021 gaaaacgact ttaggatttg aaatccgttc tgttggattg aatccttttg cttctgagta
    19081 tgcaggaatg agtagtaaac gtacgatcgt tttgtcgatg gtcatttctg gcgctttggc
    19141 agggcttggc ggtgtggttg aaggattagg aacgtatcaa aacttctttg ttcaaacgac
    19201 ttcgctatct attggatttg acggaatggc tgtttccttg cttggttctg gatcagcaat
    19261 cggtattctt ttatcagcga tcttgttcag tattttgaag atcggtggac ttggcatgca
    19321 gacaggagca ggtgttccgt ttgagatcgt caatgtatcg attgctttga ttatcttctt
    19381 tgtcgggatc aacttcctga ttcgtttcgt catggctaaa gtcttccaag ggaaaaaaca
    19441 agaagagatc gttgcgacaa tagaatcgaa accaacgaat caaaaccatg aagggggcga
    19501 actataatgt cgactatcga attaattgcc ttgatcctta cttctacact ggtttattca
    19561 acaccgctaa ttctaacgtc actaggcgga actttttctg aacgaagcgg gatcgtaaac
    19621 gtagggctag agggaatcat ggtcatgggt gcttttagtt ccatcgtttt caacttgacg
    19681 atgagtccat cacttggttc tatgacacca tggatcgcta ttttagtggg tggcgtcgta
    19741 ggtatcctat tttctctgat tcacgcagta gcaacagtca gtttgcgtgc tgaccatatt
    19801 atcagcggga cagtaattaa tctgatggca cctgctttag gtgttttctt gatcaaagca
    19861 tggtatggta aaggtcaaac tgataacatc acgcagaatc tggggtattt ttctttccca
    19921 ggattagcag atattccggt cattggacca attttcttta aaaatacatt cttacctgct
    19981 tattgtgcta ttttgattgc tgtcctagct tgggtgatca tcttcaagac gaaattcggc
    20041 ttgcgcctcc gttcagttgg tgaaaatcct caagctgccg acacattagg tatcaatgta
    20101 tatgctatgc gttattcagg cgtactgatt tctggcttgt taggcggtat gggcggtgct
    20161 gtttttgctc agtcgatttc cggtaacttt tcagctggta cgatcgttgg acaagggttc
    20221 atctccatgg ctgctatgat ctttggtaag tggaatcctt taggggcaat gggtgcctca
    20281 ttgttctttg gttttgctca aagcttgagt atcattggcg cacaattacc agttatttct
    20341 tcgattccgc cagtattgct gcaaattgct ccatatttgc tgacaatcat tgtgctggtt
    20401 gttttcttag ggaaagcttc tggtccaaaa gcaaacggga agaactatat caaatcaaaa
    20461 taatctttta gcgaataaaa agggtgggtt acgggaagtg tttttcgtct cgcccttttt
    20521 gttttaaagg caataaaaat aaaaagaaag aaggaataat catgtttaaa cgcgtacatc
    20581 tgatcgtcat ggattcagta ggaattggag aagcaccaga tgccgataag ttcggtgatg
    20641 ttggttctga tacattagga cacattgcga aagaagcagg attgaacgtt ccacatttag
    20701 agcagcttgg tttaggaacg atccgtcctc ttgaaggtgt ggaatcagtg aaagatcatc
    20761 aaggctatgc gacgaaatta gaagaagttt ctgtagggaa agatacgatg acaggccact
    20821 gggaaatcat gggattgaat atcaaaactc catttcgtgt gtttcctaat ggattccctg
    20881 atgatctgat caaacaaatc gaagaatttt ctggccgtaa agtcgtatgt aacaaacctt
    20941 atagcggaac agctgttatt gacgattacg gtgaacacca aatgaaaaca ggcgatttaa
    21001 ttgtatatac ttctgccgat cctgtccttc agatcgcggc acatgaagaa atcattcctt
    21061 tagaagaatt atatcggatt tgccaattcg ttcgtgatat aacaaaagat gatccgtata
    21121 tgattggccg aatcattgca cgtccgtacg tgggtgaacc aggagacttc acacgaacaa
    21181 gcaatcgcca tgattatgcg ttgaatccat tcggacacac agtccttgat tctttgaaag
    21241 aagcaggaaa ggacgtgatt gctgttggaa agatcaacga tattttcaac ggacaaggaa
    21301 tcactgaatc tgtccgcacg aaaagcaata tggatggcgt tgaccagctg ctgaaagtta
    21361 tgaaaaacga tttttcagga atcagcttta ccaatttagt agattttgat gcattatacg
    21421 gtcatcgtcg ggatgtagtc ggctatgcgc atgcgattga agaatttgac ttacgaattc
    21481 cagaattgct tgaagcgatg gaagaagacg acttgctaat gattacagcc gatcacggaa
    21541 acgatccgac gtttactggt accgatcata cgcgagaata tgtaccgtta ttggtttaca
    21601 gtaaaaaaat gaaagaacaa ggggcattgc ctcaaggata ttattcagat atttcagcaa
    21661 cgattgctga gaactttagt gtttcttcga ctgaaaatgg cgaaagcttc ttgaaattat
    21721 taaaataatc tttttaaata ggagaaagca aatgaccaag ttaagcgaga tgttacaaga
    21781 aacgacccag tttatccttg ataaaggagt aaaagaaatt gattttggtt tgattctagg
    21841 ttcaggatta ggtgaattag cagatgaaat cgaagatgct gtaatgattt cttatgatga
    21901 gatcccgttc tttcctgttt cgacagtagt tgggcatgca ggaaagctag tttatgggtc
    21961 tctggcaggc aagaaagtgt tagccatgca agggagattc cactactatg aaggtcattc
    22021 catgcaaaca gtgacctatc cagtacgtgt gatggccgga ctaggggccc attcagtcat
    22081 tgtgactaat gcatgtggtg gtgtcaacga atcatttgta ccaggagatt tgatgctgat
    22141 taccgatcat atcaatttta ctggtgaaaa tcctttgatc ggtccgaatg aagatgcaat
    22201 gggccctaga tttccagata tgagtcaagc ttatacgcct gactatcaag caacagcaaa
    22261 agcagcagca gaaaaactag gtttggatct taaagaaggc gtatatatgg gctattctgg
    22321 accaacttat gaaacgcctg cggagatccg aatgtctcgg acaataggag ccgatgcagt
    22381 agggatgtcg actgttccag aagtcatcgt agcagctcac agcggattaa aagtgttagg
    22441 aatctcttgt attaccaact tagcagcagg tatgcaagcg aatctgagcc atgaagaagt
    22501 tgtagaaaca actcagagag tcaaacaatc ttttaaagca ttggttaaag aaacattgac
    22561 attattgtaa taggaggaac aataaaatga gtgtgcatat tgaagcgaaa gaaggcgaga
    22621 tcgccgataa gattttactt ccgggagatc ctttgcgagc taaatatatt gcggagactt
    22681 ttttggaaga tccagtttgt tacaatcagg tacgcggtat gttaggcttt accggcaaat
    22741 ataaaggaga acgtatttct gttcaaggaa caggaatggg aatgccatca gccaccatct
    22801 atgcccatga attgatccag tcgtatggtg taaagaaatt gattcgagta ggtacatgcg
    22861 gtgcattgtc aaaagacgtc catgttcgtg atttagtact agcacaaggt gcagcgacca
    22921 gttcttcgat gatcgaaaaa aatttccaag cctttcattt tcctccaatc agtgatttca
    22981 atctattact gaaagcatat gagatagcta aagaaaaggg ctatacggtt catgtaggaa
    23041 atgttctttc ggaagattct ttctacaaag atgatttgac agagacgttc caattagctg
    23101 aacttggcgt tttaggagtg gaaatggaag cagcggctct ttattactta ggcgcgaaat
    23161 accatgtgca gacattaagt ttgatgaccg ttagcgacca tttgatcacc ggtgaagaaa
    23221 caacagctgc agaacgtcaa tctacgttca atgaaatgat cgaagtagga ttggaaacag
    23281 cgatagcaga ataagaagga aatgaaaaag ctgccctgca ttaagtaata agaacatcca
    23341 agcaaaaata gctcctcatg tttttgactt ggctggactt attattgcaa atgtaagctt
    23401 ttgaacaccg tttaccaaga ggttgtgaat ctgccgttta actctgagtc acaaggaaca
    23461 atttcaaaaa acagcttttc atgtttgatg aatattgtga cttgtgaccg agaagttggc
    23521 aggagaaaac cgtttatacg aaaaaaggga ctgtgacaaa tcgtgtcaca gtcccttttt
    23581 tatagtgttt tttataggta gtatttttta gcaactgtta agtcatcatt taattcataa
    23641 acaagtggtt gacctgttgg aatttcaaga tccatgatgt cttcgtcaga gataccttcg
    23701 atatgtttag ctagggcgcg taatgagtta ccatgtgcag ctactaaaac agttttgttg
    23761 tctagtaatg ctggagcaat ttcatcttgc cagaatggca aagcgcgttc taatgtcact
    23821 ttcaagtttt ctccaccagg aatatcgcgt ttgtctaaca ttgcgtaacg acggtcattt
    23881 gctgcagaac cttcgtcagt ttcttccatt aatggaggaa gagtatcgta agaacgacgc
    23941 cagatgtgca cttgttcgtc gccgtatttt tcagctgttt cttttttgtt caaaccttgt
    24001 aatttaccat agtgacgttc gtttaagcgc catgatttga tttgtggtac ccaaagttga
    24061 tctgaatatt ctaagatcaa gttacatgtt ttgattgcac gagttaaaac agaagtgtaa
    24121 gcaacatcaa attcgattcc agcttctttg attttgcgtc cgccttcttt tgcttcttcg
    24181 attccttctg gtgctagatt tacatcagcc caaccagtaa attggttcaa tgcattccat
    24241 tcactaagac cgtgacgaga aaaaactaat tttggcatgt ttagctctcc ttttaagata
    24301 ggtttatatt tctgaaattt tcagttctgt tttattgtac aattttttgg aagagatttc
    24361 catcgaaaaa ttagataaga ttctatgaga aaacaagtag agaatataaa aaaacgaaca
    24421 gtgcccacgc aactgttcgt ttttaggtat tagatgcata attgctcgat ttctttttca
    24481 ggtaaattga tatatttata acatgttcca actgaaacac cgcattttga agaaataaat
    24541 tggatcgttt cttttttttc ataatagaga cgtcggattt ttttgatcgt ttttgcatcg
    24601 atttttggtc ttccgccgat ttttcctttt ttacgagctt catctaatcc aactaatgta
    24661 cgttctttga tcaatgcgca ctccatgttt gctaggtttt ccattaattg gaaatagatt
    24721 tttcccattt cgcgcgtatc gattccttca tcaagactaa tcaagtgcag cccgcgatct
    24781 ttgaataatt gcgtgagttc tgttaattgc cgcgtagatt tgcctaatcg atgaagttgg
    24841 caaatgacta gtgcatcgcc ttgttgcatg tcagcgatca ctgactccaa atgaacagca
    24901 gtagaatcat tttgttccac ttcatatgtc tcatggaaaa tttcttgaca accaaagtca
    24961 gataattgat caacctgagt tgttaaatca acgtcattta tggttgtgcg tgcataacca
    25021 ataattttca tggtgattcc tttctagcag tgattttcta actggatata acagtaaaaa
    25081 tgtagcataa agtacgtcaa aaagatagtt ttttcgcaaa ttttccgctg tcttttttta
    25141 ttggatgatc aagcagtttt tctttattta cgacggattg cgtcaagaat ctcaacgcct
    25201 ttttctgagc cgacaactac tttagaaacc atgtttagga aaagcccatg ttctactacc
    25261 ccaacaagtt catctaaata ggtagctaag ctttctggct gttcgatgac ttctagatgc
    25321 agatcaatga tgtaatgacc accatctgtg gttaagactt ctccgttttc gtctgtacgc
    25381 aagacgggtt ggaatctttt ttcttcaaaa atatgaagta gctgttggga gccataaggg
    25441 atcacttcaa ctgggagtgg gaacttccca agtttatcga ctaatttaga agaatcaacg
    25501 atccaaatcg tttcttttga gtacgtagcg actattttct cgaaaagcaa agcagcgccg
    25561 ccgcctttga tcccttgaaa atcagcactg atttcatcag caccgtctat tgtcaaatcg
    25621 actacgggga cttcatcaat actctttaac ggtattccta atttttccgc ttgttctttt
    25681 gtcgcatttg aagtagtaac tcctgtgata cgtaaacctt cttcacgcat acggcgacca
    25741 atctcttcta ccatataata ggcggttgaa ccggtcccga gacctacgat catcccgtcc
    25801 tttacgaatt tcgcggcttc aatgccagct aattgtttta aattcatctt tgcgtccacc
    25861 tttttttagt ttgagcatcg tgctttcctc actattttag cgtgatttac ggtaaaaaga
    25921 taccattctt ttttattcca ataaagcttt ttcaaaaaaa attgcatctc ttgttgacat
    25981 gttttttcat tcgtgatatt ctaacaaagg tgctttatct acaggtttct gtgaagaaac
    26041 gtgctgactg tttatcaaag catatttgat aaggatgcag acattgcatt tattttttat
    26101 cacaaaaaaa gaaccacctg gatgtgtgga actagacgca aatcgtggga aggaggaaac
    26161 aaggaatgcc tacaattaac caattagtac gtaaacctcg taaatcaaag gtggaaaaat
    26221 ctaattcacc tgctttgaac aaaggatata acagctttaa gaaaactcaa actaacgtaa
    26281 actcacctca aaaacgtggg gtagcaactc gtgtgggtac aatgacacct aaaaaaccga
    26341 actcagcttt acgtaaatat gcacgtgttc gtttgtcaaa cttaattgaa gttactgctt
    26401 atatcccagg gattggtcat aacttacaag aacacagtgt tgtattatta cgcggtggtc
    26461 gtgtaaaaga cttaccaggg gtacgttacc atatcgttcg cggtgcttta gatactgctg
    26521 gtgttaacga ccgtaaacaa agccgttcta aatacggaac taaaaaacct aaagcttaat
    26581 tttaattatt aaacaaatga aacttgcttc tactatatag aagtaattac tatgaacaat
    26641 atttcggaag gaggagttac ggatgccacg taaaggtcct gttgcaaaac gtgatgtttt
    26701 accagatcct atttataact caaaattagt aactcgcttg atcaaccgtg taatggttga
    26761 cggaaaacgc gggattgcag ctaacattat ctataatgcc tttgacttga tcaaagaatc
    26821 tacaggtaac gatccattag aagtgtttga acaagcaatg aaaaacgttc aacctgttct
    26881 tgaagttaaa gcacgtcgtg ttgggggttc aaactaccaa gtaccagttg aagttcgccc
    26941 tgaacgccgc gttactctag gtcttcgttg ggtagtaaac tacgctcgct tgcgcggtga
    27001 acacacaatg gaagaacgct tagcaaaaga aatcatggat gctgcaaaca acacaggtgc
    27061 ttctgttaaa aaacgtgaag acactcataa aatggctgat gccaaccgtg cgtttgctca
    27121 ctatcgctgg taagattctc tctgtttggt cggcttttat aagtcgacct cagatagtgt
    27181 ccttattttt agcaactaga tagtaaagag aggagaaaca aggagaatga ccagagaatt
    27241 ttctttacaa aacactcgta atatcggtat catggcccac atcgatgctg gtaaaacgac
    27301 tgctactgaa cgtatcttgt actatactgg taaaatccat aaaattggtg aaactcatga
    27361 aggagcttca caaatggact ggatggaaca agaacaagaa cgtggtatta cgatcacttc
    27421 tgctgctact acagcacaat ggaagggtca ccgaatcaac atcatcgaca caccaggaca
    27481 cgtagacttc acagttgaag ttgaacgttc attgcgtgta cttgatggtg ctgtaactgt
    27541 tcttgatgca caatcaggtg ttgaacctca aactgaaaca gtttggcgtc aagcaacaac
    27601 ttatggtgta cctcgtatcg tatttgcaaa caaaatggac aagatcggtg ctgacttctt
    27661 atattcagta tcaactttac atgaccgttt gcaagcaaac gctcacccaa tccaattacc
    27721 aattggtgcg gaagacgact tcacaggaat tatcgacctt gtaacaatga aggctgaaat
    27781 gtatacaaac gatcttggaa cagagatcga agaaacagaa attcctgaag aataccgcga
    27841 attagctgaa gaatggcgcg aaaaattggt tgaagctgta gctgaaactg atgaagaact
    27901 tactttgaaa tacttagaag gtgaagaaat cactgaagct gagttaaaag aaggtatccg
    27961 ccgcgcaaca gttaacgtag aattctaccc agtactatgt ggttcagcat ttaagaacaa
    28021 aggggttcaa ttactattgg acgctgttct tgattacttg ccatcaccgt tagatatccc
    28081 agctatcaaa gggattgacc ctaaaactga tgaagaagta gaacgtcctg cagacgacag
    28141 cgctcctttc tcagctttag catttaaagt tatgactgac ccattcgtag gtcgtttaac
    28201 tttcttccgt gtgtactctg gtgttttaca atcaggttca tacgtacaaa acgcaacaaa
    28261 aggcaaacgt gaacgtgttg gtcgtatcct acagatgcat gccaactctc gttcagaaat
    28321 ctctgaagtt tacgctggag atatcgctgc tgctgttggt ttgaaagaca caactactgg
    28381 ggacacacta tgtgatgaaa agagtctagt tattcttgaa tccatggaat tcccagaacc
    28441 agttatccaa gtcgctattg aacctaaatc aaaagctgac caagataaaa tgggtgtggc
    28501 tttacaaaaa ctatctgaag aagatcctac tttccgtgct gaaacaaacg tggaaacagg
    28561 cgaaacaatc atcgctggta tgggtgaact tcacttagat atcatcgttg accgtatgcg
    28621 tcgtgaattc aaagttgaag ctaacgtagg tgcgcctcaa gtatcttacc gtgaaacttt
    28681 ccgtgctggc actcaagccg aaggtaagtt tgtacgtcag tctggtggta aaggtcaata
    28741 cggtcacgta tggattgaat ttacaccaaa tgaagaaggt gctggtttcg aatttgaaaa
    28801 tgcgatcgtc ggtggggttg ttcctcgtga atacattcca gctgttgaaa ctggtttgaa
    28861 agatgctatg gaaaatggtg tcttagctgg ctatccatta gtagatatca aagctaaact
    28921 ttacgatggt tcataccatg atgtcgattc aaatgaaact gccttccgtg ttgctgcttc
    28981 tatggcatta cgtgcagcag ctaagaaagc taatccagta atccttgaac caatcatggc
    29041 tgtagaagtt gttatccctg aagattattt aggtgatgtt atgggtcacg taactgctcg
    29101 tcgtggacgt gttgaaggta tggaagctcg cgctggcggc caacaagttg ttcgtgcgat
    29161 ggttccactt gctgaaatgt ttggttatgc tacaactctt cgttctgcta ctcaaggtcg
    29221 tggtacattt acaatgacat ttgaccacta cgaagatgta ccaaaatcag tacaagaaga
    29281 aatcattaag aaaaacggcg gaaaagctga ataatttctt gaaaccggat agtcctgcaa
    29341 agagattatc caaagagact atatttttaa tatagtttcg tgtaaaataa ttatcgatga
    29401 tatgggcatg tggtgtacct tgtgtacatc atatacctat cagacaaata aaaaatatat
    29461 tgtattttta ggaggacatt ttaaaatggc aaaagaaaaa tttgaccgtt ctaaaccaca
    29521 cgttaacatt ggtactatcg gacacgttga ccatggtaaa actacattaa cagctgcaat
    29581 cacaactgta ctatctaaga aaaacggcgg ccaagctatg gcttacgatc aaatcgatgg
    29641 tgctccagaa gaacgcgaac gcggaatcac aatctcaaca gctcacgttg agtatgaaac
    29701 agatacacgc cactacgctc acgttgactg cccaggacac gcggattacg ttaaaaacat
    29761 gatcactggt gctgctcaaa tggacggagc tatcttggta gtttctgctg ctgacggccc
    29821 aatgcctcaa actcgtgaac acatcctatt gtctcgtcaa gttggtgttc cttacatcgt
    29881 tgtattcttg aacaaagtag acatggttga tgacgaagaa ttactagaat tagttgaaat
    29941 ggaagttcgt gacctattaa cagaatacga attccctggt gacgatgttc ctgtagttgc
    30001 tggatcagct ttgaaagctc tagaaggcga cgcttcatac gaagaaaaaa ttcttgaatt
    30061 aatggctgca gttgacgaat acatcccaac tccagaacgt gacaacgaca aaccattcat
    30121 gatgccagtt gaagacgtgt tctcaattac tggacgtggt actgttgcta caggtcgtgt
    30181 tgaacgtgga caagttcgcg ttggtgacga agttgaagtt gttggtattg ctgaagaaac
    30241 ttcaaaaaca acagttactg gtgttgaaat gttccgtaaa ttgttagact acgctgaagc
    30301 tggagacaac attggtgctt tactacgtgg tgttgcacgt gaagacatcc aacgtggaca
    30361 agttttagct aaaccaggta caatcacacc tcatacaaaa ttctctgcag aagtatacgt
    30421 gttgacaaaa gaagaaggtg gacgtcatac tccattcttc actaactacc gtccacaatt
    30481 ctacttccgt acaactgacg taacaggtgt tgttgaatta ccagaaggaa ctgaaatggt
    30541 tatgcctggc gacaacgtaa caatggaagt tgaattaatc cacccaatcg ctatcgaaaa
    30601 cggtactaaa ttctcaatcc gtgaaggcgg acgtacagtt ggtgccggtg tcgttacaga
    30661 aatcaaagct taattcactt aagttttaaa gtaaagcaac atttattcgg acgtaatcgc
    30721 tcggaacgaa ggtcttagga tctttgttcc gagctttttt atttattgca ggatcaggaa
    30781 aaaagacagg agtattataa atagaagaaa cacgaaataa aagagtcagt attttctaaa
    30841 tgaaacttta tgaaaacaaa atgtttttta caagaaaaag ccttgctttg tgagtttata
    30901 tatattataa tgacaaaggt gcgtttactt tagtgaattg cacagacgta atcagaatga
    30961 tttcgtcggc taagaaacga gaggttgcga cacgcccgga cgctttgcca cgaacgagcg
    31021 tgacggaaat tttcgtggag ctatgtctac ttttcaaaat aggcgaagga gggaacaaga
    31081 tggcaaaaca aaaaattcgt atccgtttaa aagcgtatga acaccgtatt ttagatcaat
    31141 cagcggataa aatcgtggaa actgcaaaaa gaactggagc tagcgtgtct ggtccaattc
    31201 cattaccaac tgaacgcagt ctttacacaa tcatccgtgc gactcataaa tacaaagatt
    31261 cacgcgaaca attcgaaatg cgtacacaca aacgtcttat cgacattgtg aacccaacac
    31321 caaaaactgt tgatgctttg atgaagctag acttaccatc tggtgtaaac atcgaaatca
    31381 aattataaaa ctaaaacaaa aataatggag gtgtactcat gaccaaagga atcttaggga
    31441 aaaaagtggg aatgacacaa atcttcactg aatctggtga attaattcca gtaactgttg
    31501 tagaagctac tccaaacgta gtactacaag tgaaaacaat ggaaacggat ggctacgaag
    31561 ctattcaagt tggttaccaa gatatgcgtg aagttttatc aaacaaacct gcgaaaggtc
    31621 atgttgcaaa agcaaacacg gctcctaagc gcttcattcg tgaattcaaa aatgttgagc
    31681 taggagaata tgaagtagga aaagaaatta cagtagatgt tttccaagca ggagacatta
    31741 ttgatgtaac aggtactacg aaaggtaaag gattccaagg ggttatcaaa cgccacggac
    31801 aaagccgcgg accaatggct cacggttctc gttaccatcg tcgtcctggg tcaatgggtc
    31861 cagttgcacc taaccgtgta tttaaaaaca aacgtcttgc tggccgtatg ggtggcaacc
    31921 gcgtaactat ccaaaacttg gaagttgtac gtgtcgatgc agaaagaaat gttatcttga
    31981 tcaaaggtaa tgttcctgga gctaaaaaat ctttaattac tatcaaatca gctgtgaaag
    32041 ctaaataatt gtaggaagaa aggaggaact aaggaatgcc gaatgtagca ttattcaaac
    32101 aagatggaag ccaaaacggt gaaatcacac ttaacgaaga aatcttcgga attgaaccta
    32161 atgaaagtgt tgtttacgat gcaatcgtaa tgcaacgtgc gtcattaaga caaggaacac
    32221 acgcggttaa aaaccgtagc gctgttcgcg gcggcggacg taaaccatgg cgtcaaaaag
    32281 gaacaggtcg tgcacgtcaa ggatctatcc gctcaccaca atggcgtgga ggtggcgtag
    32341 tctttggacc aacaccacgt tcttacagct acaaacttcc taaaaaagtt cgtcgtttag
    32401 caatgaaatc tgtattgtca gaaaaagttg ctgaaaacaa cttggtagca atcgaaggct
    32461 tgaacttcga cgcaccaaaa acaaaagaat tcaaacaagt tcttgctaac ttatctatcg
    32521 actctaaagt attggttgtt ctagaaaaag gtaacgactt tgctgcttta tcagcacgta
    32581 acttaccaaa cgtttctgta gtaacttctg ataatgtgag tgtgctagac gttgtatcaa
    32641 atacaaaagt gttagcaaca caaactgctc ttactcaaat tgaggaggtg cttgcataat
    32701 gaacttacta gacgtaatca aacgcccagt gatcactgaa aaatcaatgc ttgccatgga
    32761 tgacaagaaa tacacttttg aagtggacac tcgcgcaaac aaaactttag taaaacaagc
    32821 ggtagaagct gcttttgacg ttaaagtcaa aaacgtgaac atcgtgaacg tacgtgcgaa
    32881 attcaaacgt atgggcaaat atgcaggata tacaaaaaaa cgtcgcaaag cgatcgttac
    32941 attgactgaa gattcaaaag aaatccaatt attcgaagct gctgaataag cactaataga
    33001 taactcatta aattaggagg gaaaaacgtg gcgattaaaa agtacaaacc tacctcaaat
    33061 ggtcgtcgta acatgacagg ttctgatttt gctgaaatca caacatcaac acctgaaaaa
    33121 tcattgttac aaccattgaa aaaccatgct ggacgtaaca acaacggccg catcactgta
    33181 cgtcatcaag gtggcggaca caaacgccaa tatcgcgtga tcgacttcaa acgtaacaaa
    33241 gataacgttg ttgcaactgt tcaaacgatc gaatatgatc caaaccgttc agctaacatc
    33301 gcgttagtac actatgaaga tggagtgaaa gcttacatct tagcacctaa aggactagaa
    33361 gtgggtatga aacttgtttc aggtccagaa gcagatatca aagtcggaaa tgctcttcca
    33421 ttagaaaaca ttccagttgg tactgttatc cacaacattg aaatgaaacc tggtaaaggt
    33481 ggacaattga tccgttctgc tggtacaagt gctcaagtac ttggtaaaga aggcaaatac
    33541 gtattgatcc gcttgaactc tggtgaagtt cgtatgatct tagctgcatg ccgtgctaca
    33601 atcggttctg taggtaacga acaacacgaa ttaatcaaca tcggtaaagc tggacgctct
    33661 cgttggatgc gtaaacgccc aactgtacgt ggtagcgtaa tgaaccctaa tgatcaccca
    33721 cacggtggtg gtgaaggtaa agctcctatc ggacgtaaag caccagtttc tccttggggt
    33781 caaccagctc ttggttacaa aactcgtaac aaaaaagcta aatcagacaa acttattgtt
    33841 cgtcgtcgca aaaataaata attactttga ccatgtgtcg cacattttga gaggaggttc
    33901 accatgggtc gtagtttaaa gaaaggacct tttgtcgatg agcatttaat gaaaaaagtt
    33961 gaagctcaag caggggttga aaagaaaaaa gttatcaaaa cttggtcacg ccgttcaaca
    34021 gttttcccaa gttttgttgg atataccatc gcagtttatg atggacgtaa acatgtacca
    34081 gtttacatcc aagaagacat ggtaggacac aaattaggtg aatttgcacc tacaagaact
    34141 tatcgtggac atgctgctga cgataagaaa acgaaacgct aatttgaggg gaggataaat
    34201 ccaaatggca gaacaaatca catcagctaa agcaactgca aaaacagttc gcacttcacc
    34261 tcgaaaagcc cgtttagtaa ttgaccttat cagaggtaaa agtgtcgcag atgcaatttc
    34321 aatcttgaaa ttcacaccaa acaaatctgc tggaatcatt gaaaaagtat tgatgtcagc
    34381 agttgcgaat gcagaaaata actttgactt agatgttgaa aacttggtag taagcgaagc
    34441 ttttgttaac gaaggaccta caatgaaacg tttccgtcct cgtgcaaaag gatcagcttc
    34501 tccaatcaac aaacgtacaa gtcatatcac ggtagtcgta tcagaaaaat aaggagggat
    34561 aatcagtggg tcaaaaagta catccaattg gaatgcgtgt aggcatcatc cgcgactggg
    34621 atgctaaatg gtatgctgaa aaagagtatg ctgagttctt acacgaagat ttaagaatcc
    34681 gtaaatttat ttcaactaaa cttgctgatg ctgctgtatc aacagttgaa atcgaacgcg
    34741 caacaggtcg cgtaaacatt tcaattcaca cagctaaacc aggtatggtt attggtaaag
    34801 gcggttctga agtcgaaagc ctaagaaaag aattaaacaa attaactggt aaaagaatcc
    34861 atatcaatat cgtggaaatc aaaaaaccag atctagatgc aaaattagta ggtgaaggaa
    34921 tcgcacgtca attagaaaac cgtgttgctt tccgtcgcgc tcaaaaacaa gccatccaac
    34981 gctcaatgcg tgctggcgct caagggatca aaactcaagt atctggtcgt ctaaacggag
    35041 cagatatcgc tcgttcagaa ggatactcag aaggaactgt tcctcttcat actttacgtg
    35101 cggacattga ttacgcatgg gaagaagcag atacaacata cggaaaacta ggagttaaag
    35161 tgtggatcta tcgtggagaa attcttccaa ctaaaaaaaa cactgagaaa ggagggaaat
    35221 aatcatgtta gtacctaaac gtgtaaaaca ccgtcgtgaa ttccgcggaa aaatgcgcgg
    35281 ggaagctaaa ggcggaaaag aagtagcatt cggtgaatac ggtttgcaag ctgttgattc
    35341 acattggatc acaaaccgcc aaatcgaagc tgctcgtatc gcaatgactc gttacatgaa
    35401 acgtggtggg aaagtatgga ttaaaatttt ccctcacaaa tcttatactg ccaaagcaat
    35461 tggggtacgt atgggttctg gtaaaggggc acctgaagga tgggttgcac cagtaaaacg
    35521 tggtaaaatc atgtttgaaa tcgcaggcgt tcctgaagaa gtagctcgtg aagcgttacg
    35581 tctagcttct cacaaattac caatgaaaac taagatcgta aaacgtgagg aaatgggtgg
    35641 tgaatcgaat gaaggttaaa gaaatcagag aattaaccac tgccgaaatg cttgatcaag
    35701 aaaaacaatt aaaagaagaa ttgtttaatc ttagattcca attagcaaca ggtcaattag
    35761 aaaacactgc acgtattaaa gaagtacgta aatcgattgc acgcatcaaa actgtgttgc
    35821 gtgaacaagc taagtaatta tggaaggagg ccattaagcg tatgactgaa ggaagaaatc
    35881 aacgcaaagt ttatcaaggt cgcgtggttt cagacaaaat ggataaaaca attaccgttg
    35941 ctgtcgaaac aaagaaaaac caccctatct atggcaaacg catgaactat tctaagaaat
    36001 acaaagtgca tgatgaaaac aacacagcaa aagttggcga catcgtgaga attatggaaa
    36061 ctcgtccatt atcagctaca aaacgtttcc gtttgttgga agtagtcgaa gaagcagtta
    36121 ttatctaata acacgagatt ttcctatata gattgaatgc aaaatctgaa aggaggatac
    36181 acaacgtgat ccaagcagaa agtcgtttaa aagtcgctga taactcaggc gcacgtgaaa
    36241 ttttgacgat caaagtcctt ggtggatctg gtcgtaaaac tgctaacatc ggtgatgtga
    36301 tcgttgctac ggttaaacaa gcaacgccag gtggggttgt caaaaaaggt gacgtcgtta
    36361 aagccgttat cgttcgaaca aaatcaggag ctcgtcgtac agacggttca tatattaaat
    36421 ttgatgaaaa tgctgcagtg attattcgtg atgataaaag ccctcgtgga acacgtatct
    36481 ttgggccagt tgcacgtgaa ctacgtgaaa acaacttcat gaagatcgtt tcactagcac
    36541 cagaagtttt ataatcttga gacacttatc aaaggaggtg cgaaacagtt atgtttgtta
    36601 aaaaaggcga taaagttaaa gttatcactg gaaaagacaa aaacaaagaa ggcgttgtac
    36661 tagcagcgtt cccgaaaaaa gataaagtta ttgtcgaagg tgtaaatgtc gttaaaaaac
    36721 accaaaaacc ttctcaagct gctcctcaag gtggaattgt tgagatggaa gcgccaattc
    36781 atgtttctaa cgtgatggtg gttgactcta ctggtgtagc tggccgagtt ggctacaaag
    36841 aagtagacgg caaaaaagtc cgtgtttcta aaaaaaccgg tgaagtttta gataaataaa
    36901 agtttaagga aggagggtct tactgaatga accgcctaaa agaaaaatat cttaaagaag
    36961 taactccatc attgatggaa aaatttaact atagctctgt tatgcaaaca cctaaagttg
    37021 aaaaaatcgt catcaacatg ggtgttggtg atgcggtatc aaacgctaaa aacttagata
    37081 aagcagttga agaattaact ttgatcactg gtcaaaaacc aatgattaca aaagctaaaa
    37141 aatcaatcgc tggattccgt ttacgtgaag gaatgccaat tggtgcaaaa gttacattgc
    37201 gcggagaaag aatgtacgaa ttcttagaca aattggtttc tgtttcacta ccacgtgtac
    37261 gtgacttcca tggtgtaagt aaaaaagcct ttgacggtcg tggaaactat actttaggta
    37321 ttaaagaaca attgatcttc ccagaagtag attatgattt agtagataaa gtacgtggta
    37381 tggacatcgt tattgtaaca acagcaaact ctgatgaaga atctcgtgag ttgttgacac
    37441 aattaggcat gccattccaa aaataattaa aggaggcgaa ctacgtggct aaaaaatcaa
    37501 tgattgctaa aaacaaacgt cctgcaaaat tttcaacaca agcttatact cgttgcgaac
    37561 gttgcggacg tccacattca gtttatcgta agttccatct ttgccgtatt tgcttccgcg
    37621 aacttgccta taaaggtcaa attcccggcg tgaagaaagc tagctggtaa aaagtaaatt
    37681 cgcataagaa ggaggtaaaa gatcaatggt catgacagat ccaattgcag attttctaac
    37741 tcgtatccgt aacgcaaaca tggttaaaca tgagtcttta gaagtacctg catcaaaaat
    37801 taaacgtgac atcgctgaaa tcttgaaacg tgaaggtttc gttcgtgatg ttgaatacat
    37861 cgaagatgac aaacaaggcg tgatccgtgt tttcctaaaa tttggtaaaa acggcgaacg
    37921 tgttatcaca aacttaaaac gtatctctaa accaggtttg cgtgcttatg tcaaagctga
    37981 cgaagtacca aaagtattga acggtttagg tatcgcaatc atttcgactt ctgaaggtgt
    38041 tgtcactgat aaagaagctc gtgaaaaaaa tatcggcggc gaagttatcg cttacgtatg
    38101 gtaatcaagt agaatctaca aggaggtgtc tttaagtgag ccgtatcgga aataaagtcg
    38161 ttgttatccc tgaaggagta acagttactc aagacggaaa caacgttaca gttaaaggac
    38221 caaaaggtga attgactcgt actttttcag cagatatcaa aatgaatatc gaaggaaacg
    38281 aagtaacttt cactcgtcca aacgacagta aagaaatgaa aacaattcat ggaacaactc
    38341 gtgcgaactt caacaacatg gttgtaggtg tcagcgaagg tttccaaaaa gcgttagaac
    38401 taatcggggt tgggtaccgt gcacaattac aaggatcaaa acttgtattg aacgttggtt
    38461 actcacatcc agtagaaatc acaccaccag ctggagtaac tgttgaagta ccagctaaca
    38521 cacaagtaat tgttaaaggt gcgaacaaag aagaagttgg cgaattagct gcaaacattc
    38581 gtggaactcg tcctccagaa ccttataaag gtaaaggtat tcgttatgtt ggcgaatatg
    38641 tacgccgtaa agaaggtaaa actggtaaat aatcgtttag aaaaattgca tagaagccag
    38701 cagcaggaaa aaggcatttg gctgaagttt accttcaaaa aaatacattt ttacttgtgc
    38761 cgcagcttct atttttcgaa acgtatttac tgcttgaaat agtagtacaa taaaaataaa
    38821 gaggtgacaa ttgtgattac aaaaccagat aagaacaaaa cacgtcaaaa gagacatcgt
    38881 cgtgtacgta acaatatctc tggtactgct gagcgcccac gcttgaacgt ttttcgttct
    38941 aacaaaaaca tctacgctca aattattgat gacgtagcgg gtgtaacgct agcaagtgcc
    39001 tctaccttgg ataaagaaat ttcaggtgga acaaaaacag aagcagcaca agctgtcggt
    39061 aaactagttg ctgaacgtgc agctgaaaaa ggcattaaag tagtagtctt tgaccgtggt
    39121 ggataccttt accatggccg tgtgcaagct ttagctgaag ctgctcgcga aaatggacta
    39181 gaattttaga agaaggagga ataccattca tggtttatat cgatccaaaa catttggaat
    39241 tagaagaccg cgttgttgca attaaccgtg taacaaaagt tgttaaaggt ggacgtcgtc
    39301 tacgttttgc tgctttagtt gttgtcggtg acaaaaacgg acacgtaggg tttggtacag
    39361 gtaaagctca agaagttcct gaagcaatcc gtaaagcaat tgaagatgcg aagaaaaact
    39421 tagttgaagt acctatggtt ggttcaacaa tcccacacga agtaatcggt gcttttagtg
    39481 gtggtagaat cctaatgaaa cctgctgtag aaggttctgg ggttgctgct ggtggaccag
    39541 ttcgtgccgt attagaatta gctggggtag cagatatcac ttctaaatct ttaggctcaa
    39601 atacaccaat caacgttgtt cgcgcaacag ttgaaggttt gaaacaattg aaacgtgcag
    39661 aagaagttgc agaacttcgc ggcaaatcag ttgaagaatt aatcggataa ggaggacaac
    39721 aataatggct gaattaaaag ttactttaaa acgcagtatt atcggacgtc ctcaaaacca
    39781 acgcgataca gttaaagcgt taggtcttac aaagattaac agttcagtgg ttaagccttc
    39841 taatgaagca attaaaggca tgatcaatac tgtttctcac ctagtggacg ttgaagaaat
    39901 ttaatttaga aaaatcataa ctagaacatt aaggaggtgc caaacctatg aaacttcatg
    39961 aattaaaacc tgctgaaggt tcacgccaag tacgtaaccg tgttggtcgt ggtacttcat
    40021 ctggtaacgg aaaaactgcc ggacgcggac aaaaaggaca aaaagctcgt tcaggcggcg
    40081 gtgtgcgttt aggatttgaa gggggacaaa caccattgtt ccgtcgttta ccaaaacgag
    40141 gattcacaaa cgtgaaccgt aaagactatg cagtcattaa tcttgatgta ttgaaccgct
    40201 ttgaagacgg agctgaagta actcctgttg ctttagttga agctggaatc gtgaaaaacg
    40261 aaaaagctgg aatcaaagta ttagctaatg gggaactaaa caagaaatta actgtgaaag
    40321 cagcaaaatt ctctaaagca gctcaagaag caattgaagc ggctggtgga tcaatcgagg
    40381 tgatctaatg tttagactat taaaagatgc ttttaaagta aaagacatta gatcgaaaat
    40441 cctatttact gtatttgtgt tgtttgtatt tcgcctaggt gcacatatta ctgtaccagg
    40501 cgtaaatgct gcttcattgc aaaacctttc ttctttgcca tttttcaaca tgttgaactt
    40561 ggtaagtggt agtgcgatgc aaaacttttc cattttctca atgggggttt caccatacat
    40621 tactgcttct atcgtcattc agcttcttca aatggacatc gtgcctcgat ttgttgaatg
    40681 gtcgaaacaa ggggaagttg gtcgtaaaaa actgaatcaa gcgactcgat atctgacatt
    40741 agtattggca tttatccaat ctgtcggtat cactgctgga ttcaatcaat acgctcaatt
    40801 aggtttcgtg aataatccta acgtagcaac ttacgtaacg atcggtttga ttctaacagc
    40861 cggtacgatg tttgttactt ggctaggaga acagatcaca gaaaaaggta tcggaaatgg
    40921 cgtatcaatg atcatttttg caggtatcat ttctagattg cctgaaagta tcagagaaat
    40981 ttatgaagat tactttataa atattgatcc ttcagacata tggaaatctg ctatttttgt
    41041 ggccatttta ctagtagcgg tcttgttgat cgtgacattc gtaacatttt tccaacaagc
    41101 tgaacgcaag atcccgatcc aatatacgaa acgcgtagct ggcgcgccta caagcagcta
    41161 tctgccgttg aaagtaaatg cagctggagt tattccagtt atctttgcta gttcgtttat
    41221 tgctacgcca aatgctgttt tacaagcatt gagcggtaga ttcggttctg aaaactggta
    41281 caaagtgatg atggagatct ttaactataa tacagcacct ggtgctacga tttatacgat
    41341 tctgatcgtt gccttcactt tcttctacgc ctttgttcaa gtaaaccctg agaaattagc
    41401 ggaaaacttg caaaagcaag gaagttatat accaagcgta cgccctggta aggggactga
    41461 agagtatgtc tcaagattac tgatgcgttt aagtacagtt ggtgcagtct tccttggttt
    41521 agtggcattg cttccaatca ttgctcaaat ggtttgggat cttccacaat caatcggatt
    41581 aggcggtaca agcttactga tcgttatcgg tgtagcttta gaaactgcga aacagttaga
    41641 aggcttaatg ctgaaacgta aatatgttgg attcattgag taagaaagcg tgttgaggtt
    41701 tcccctcaac acacgttctc acacatttat taggagggaa aacaatgaac ctcattttaa
    41761 tggggctgcc aggcgcaggt aaaggaacac aagctgaaaa aatcattgat gcttatggta
    41821 ttccgcacat ctcaacagga gatatgttcc gcgcagcgat gcaaaacgaa acagctcttg
    41881 gcctggaagc aaagtcttat atggataaag gtgcattagt tcctgatgaa gtaacaaatg
    41941 gaatcgtgaa agagcgacta gctgaaccag atacagagaa aggcttctta ttagatggct
    42001 ttccacgtac gctagatcaa gcaaaagctc tggacgcaat gctaaaagat ttgaataaaa
    42061 aaattgatgc tgtcatcgat atccatgttg gtgaagaaat cttggtcgaa cgtctagccg
    42121 gccgatttat ctgcagcaat tgtggagcaa cttaccataa aattttcaac cctacaaaag
    42181 ttgaagacac atgtgatcgt tgcggtgggc atgaattcta tcaaagagaa gatgataaac
    42241 ctgagacggt taaaaatcgt ctggctatca acatcaaaaa tagtgaacca atcttggctt
    42301 attataaaga acaaggtttg ctaaacacta ttgatggtgc tcgtgaaatc gatgctgtat
    42361 ttgcagatgt acaaaaaatc attgaaaaat agcacgattg cccgtagccg acttgcatta
    42421 tgcagttact cttgtcaagt tcaataaatt atgatagaat atgtcagtcc gacttctaga
    42481 gaatcctcta gatgatccat tttgagaatt ttgaggtggg aactgcagtt tccgccattt
    42541 tatcgtgtga aaatgcgaaa caagtacaag gaggtactgt gcgtggcaaa agaagatatg
    42601 attgaagtcg aaggtacagt cgtcgaaact ttgccgaatg caatgtttaa agttgaacta
    42661 gaaaacggac accaagttct tgctactgtt tcaggtaaaa ttcgtatgca ttacatccgt
    42721 atcttacctg gtgacaaagt aacggttgaa ttgtctccat acgatcttaa ccgtggccgt
    42781 attacttatc gctttaaata attgtactcc gtaaaactac aggaggtatt atcatgaaag
    42841 taagaccatc agtaaaacca atgtgcgaac attgtaaagt aattcgtcgt aaaggacgcg
    42901 ttatggtgat ttgcccagca aatccaaaac ataaacaacg tcaaggataa ttggaggtgc
    42961 tataaatatg gctcgtattg caggagtaga tattcctcgt gataaacgtg tagtagtttc
    43021 acttacttat atctatggta ttggtaacac tactgctaaa aagatcttag ctgatgctgg
    43081 tgtatctgaa gatgttcgcg ttcgtgaatt aacgaatgaa caaacagatg ctatccgtgc
    43141 agaagtagat aaattaaaag ttgaagggga tcttcgtcgt gaagtgaact tgaacatcaa
    43201 acgtttgatg gaaatcggtt cttaccgtgg aatccgtcat cgccgtggat tgcctgttcg
    43261 tggacaaaac acgaaaaaca atgcacgtac tcgtaaaggc ccagctcgcg ctatcgctgg
    43321 caagaaaaaa taattcttaa gtgaaggagg ttaaaacttc atggcagcaa aaaaagtgaa
    43381 tcgtaaacgc cgtgtgaaga agaatataga agcaggtatt gcacatatcc attctacatt
    43441 caataacact atcatcatga tcactgatac tcacggaaat gcattagcgt ggtcatcagc
    43501 tggttcatta ggtttcaaag gaagcaaaaa atcaactcct tttgccgctc aaatggcagc
    43561 agaaactgct acaaaagcag caatggaaca cggattaaag actgttgaag taacagttaa
    43621 aggacctggt tctggacgtg aagcagcaat tcgttcatta caagctacag gtttagaagt
    43681 gactgcaatt cgtgacgtga ctccagttcc tcataatggt gcccgccctc caaaacgccg
    43741 tcgtgtttaa tgagtgccgc tcattttgag ttttatcagt aacgtcattg aacaagacac
    43801 ttttcgtttt gaaaggggta aagataagaa tgattgagtt cgaaaaacca agaatcgcaa
    43861 aaattgatga agaaaaagat tatggcaagt tcatcgttga acctcttgaa agagggtatg
    43921 ggactacttt agggaattcc ctacgtcgta ttttattatc ttctttgcca ggtgctgcca
    43981 tcactaatat tcaaatcgat ggtgtactgc atgaattctc taccatcaaa ggtgttagag
    44041 aagacgtcac tcaaatcatc ttgaacatta aaggcttagc gctgaaaatg tatggccaag
    44101 aagaaaaaac ccttgaaatc gatattaccg gacctgctac agtaactgct ggcgatatta
    44161 tcgttgatag tgatgtagaa attcttaaca aagatatgta catctgtagt gtctctgaag
    44221 gagctacgtt ccatgctcgc ttaacagtga aacctggacg tggttatgtt caagcagatg
    44281 aaaataaaaa agaagatatg ccaattggcg ttcttccagt cgattcaatc tacacacctg
    44341 ttcgtcgtgt gaactatcaa gttgagaaca cacgtgttgg acaccgtgaa gattttgata
    44401 aattgacgat ggagatttgg acagatggtt caattgaacc gttggaagca atgagtttgt
    44461 ctgcgaaaat catgactgaa catttggata tttttgtgaa cttaactgat gaagcaaaaa
    44521 atgctgaaat catggtcgaa aaagaagaaa cacaaaaaga aaaaatgttg gaaatgacga
    44581 tcgaagagtt agacttgtct gttcgctctt acaattgttt gaaacgtgca ggaatcaata
    44641 ctgtacaaga acttacaaat aaatctgagc ctgaaatgat caaagtccgt aacttaggac
    44701 gtaaatcatt agaagaagtt aaagcaaaat tgcacgactt aggtttaggt ttacgtaaag
    44761 aagattaaaa ccttttacga aggagggaaa ccaacgtgag ttatcgtaaa ctaggacgca
    44821 catctagcca acgtaaagcg atgttgcgtg atttaacaac tgatttatta atcaacgaac
    44881 gtattgtgac tactgaagct cgtgcgaaag aagttcgctc aactgcagaa aaaatgatca
    44941 ctttaggtaa acgcggagat ttgcatgcac gtcgtcaagc tgcggctttc gtacgtaatg
    45001 aagttgccag cgtgcgtgaa gaaaatgagg acatcgtcat tgaatcagct ttacaaaaac
    45061 tgttcaacga tattgcacct cgttacgcag aacgtcaagg cggatacaca cgcattttga
    45121 agacagaacc aagacgcggt gatggtgcac caatggttgt cttagaactt gtctaaaatc
    45181 acactaataa catcacttta tagatgattc ttttagagtg ttatgatgtt ggaagatatt
    45241 tttccgagtc tagctcagcg ctgctcctca agcgaatatc gcttggggag taagcactca
    45301 tcataaagtg tttttttata ccttcaatta cctgtcatga cagatatgtt tgaaggcata
    45361 aaaaaacatt ttaagcgaga aataattgaa aattttgtct ttttttgata gtgttagtag
    45421 gaactttagg atgaagaagg agtaatcatg gagccaatta ttgaattaga aaagataaat
    45481 tataaatacc agccagatga tcttcgcccc gcattgaaag atgtctcctt tacaattgat
    45541 aaaggtgagt ggatcgctat tattggacac aatggttcag gaaaatcgac acttgccaaa
    45601 acgatcaatg gattgcttct gccagaatca gggatcgtga aagtgggaaa tcaaatattg
    45661 gatgaagaaa atatttggac gatccgacag atggttggaa tggtttttca aaatccagac
    45721 aatcagtttg ttggttcgac agtagaagat gacgttgctt ttggtcttga aaatcaaggg
    45781 attcccagag aagaaatgct agtgcgtgtg aaagatgcac ttgagaaagt tagaatggct
    45841 gagtttgctt cacgcgagcc tgctcgttta tcaggagggc aaaaacaacg tgttgccatt
    45901 gccggcgtgg ttgccttacg acctgatatc attattttag atgaagcaac cagtatgcta
    45961 gatccagaag gtcgtgaaga agtgatctct acgatcaaga agatcaaaga agaaagtcaa
    46021 ttgaccgtta tatctatcac tcatgatatt gatgaagcag ctaatgccaa tcggatacta
    46081 gtgatgagac aaggcgaact tgtccgtgaa ggtacaccaa aagaaatttt ttctgctggt
    46141 cctgaactga tcgacttagg tctagatcta ccatttcctg aaaaactgaa gagcgcactg
    46201 aaagaacgtg gggttgatgt gcccagtgaa tatatgacag aagaaaggat ggtggattgg
    46261 ttatggacat ccgttttgaa caagtagact tcacttatca gccgaataca ccatttgaac
    46321 aaagagcctt atttgacatc aatatgacga tcaaagaaaa cagttatact gcattagtag
    46381 ggcataccgg aagcgggaaa tcaaccttac ttcagcattt gaatgcgctt gttaagccaa
    46441 caagcggtac agtccatatt ggagaacgag atattcagcc ggatacggat aataagaatt
    46501 taaagcccat ccgaaaaaaa gttggcatcg tctttcagtt tccagaagca cagctattcg
    46561 aagaaacggt agcaaaagac attgctttcg gtcctaaaaa ctttggtgtc agcgaagaag
    46621 aagcactagt cctagcaaaa gaaacattag aacaagttgg gctggatgaa agctatttgg
    46681 aacgttcgcc atttgaactt tcaggagggc aaatgcgtag agtagcaatc gctggtgtgc
    46741 ttgccatgag gccggaagta cttgtattgg atgaaccaac ggcaggactt gatccccagg
    46801 gtagaaaaga aatgatggag atgttttggc gtcttcataa ggaacagcag atcactattg
    46861 tattagttac gcatttaatg gatgatgtag ccaattttgc agattatgtc tatgtgttgg
    46921 aaaagggacg aatcgttaat agcggggagc cgcaagaggt ctttcaaaac attgaatggc
    46981 taaaagaaaa acaactaggc gtacctactg ccaccgagtt tgcagaagaa ttaatggcta
    47041 aagggatgaa ctttgctacc ttgcctttga cagctgaaga attagcagac gctatcgtcc
    47101 attatgctgg aggaaatgcc catgatgaat aaattgatat ttggtcgtta tatgcctgga
    47161 gattccttga tccatcgatt ggatccccga gctaaattat tagccagttt ttattttatc
    47221 ggaatcattt ttttagcaaa taattgggaa acgtaccttt tgttggcatt tttcacatta
    47281 ctttctgtct tcttgtcaaa agtagatttg aaatttttta tccgaggcat tcgcccattg
    47341 atctggctaa tcctcttcac tgtagctttg caggtcttgt ttacaagtgg cggagaaact
    47401 tattggagtt ggggtgtttt ccatatcact gaatttggtg tgatgaacgg cctctttatt
    47461 ttctgtcgat tcgtgttgat catttttatg tcgactctac tcacgcttac tacaccgcct
    47521 ttggaattat cggatgcgat tgagtacttg cttcgtccat tgaaagccgt acggttccca
    47581 gtccacgaaa tttcattgat gctgtcgatt gctcttcgtt ttgtgcctac attgatggac
    47641 gaaacagaaa agatcatgaa cgctcagcgc gctcgcggtg ttgattttgg tgaaggaaac
    47701 ctagttcaga aaatgaaagc agtcattcct ttgctgattc ctttatttgt cagcagcttc
    47761 aaccgtgcgg aagatcttgc gactgctatg gaagcaagag gctacaaagg tggggaagga
    47821 agaacgaaat atcgtgtatt gcattggcat aatagagaca cgatggttat cattgctttt
    47881 gtattattaa ctgtgctact gatctttttg agaggataaa cgttcagtgg gccgctatct
    47941 attcttttct tgctgatctg tttgcaagaa aggatgcgag cagtgtatga caagaaatat
    48001 tagggtctgt ggcagactaa ggtcacaggc ctctttcttt tatctgaaaa gaaagaacga
    48061 aaaaatttta taaaaaaatc attattccag ataacctttt aggaacaaag gagagaaaaa
    48121 catggtacgt tacaaagcaa tcattgcata cgacggaaca aattttaatg gattccaaaa
    48181 acagccaaat gggcgtactg ttcaagaaga agtagaaaaa acattacaaa aaatggcaaa
    48241 tggaaaagaa atcacggtct ttggttcggg aaggacagat gccggagtac atgcgattgg
    48301 gcaagtaatc cattttgatt atccagagga gcgtccgtta gaacgaatgc gtttcgcgct
    48361 agatacccag tcaccagagg atattgctgt aagacaagta gaaattgttt cagaagactt
    48421 ccacgcaaga tatttggtca aagaaaagac gtatcaattt cgagtggata tagggaaacc
    48481 acgcagtcct tttcgacgcc attatgcaag ttattttcct taccctcttg atttggaaaa
    48541 aattcagcgg gcgcttcctg atttattagg gactcacgat ttcacctctt tttgtgcatc
    48601 aggaagctcg atagaggata aagtacgtac gatctacgag gctaagatgg aggtaaatga
    48661 aacaaaagac gaattgttgt ttacatttag gggaaatggc ttcttgtata agatgatacg
    48721 gatcttagta ggaacgcttt tgaaaattgg caatggccga ttgcctgaag atagtatccc
    48781 agatattatt gcgaaaaaag atcgtaatgc agcaggacct acagcacatc ctgaaggact
    48841 ttatttgtat gaagtgaaat atgaataaga ggttgtgaca gaagtggtca gcttcaagaa
    48901 ataagaagga atttacgaaa attacttctc aaaattttgc aaaatttcgg cttattttcg
    48961 aaggagctac ttctggaaca ccgtgaatca gaggttgtga aaaagctgcc ctgcatcaag
    49021 taataagaac aaccaaacaa aaatagctcg tcatattttt cgtttggttg ggcttattac
    49081 cgcagatgca agcttttgaa caccgtttaa ggaagaggtt gtgaaatcag cgttttgacc
    49141 tgagtattag agaaacaaac ggaaaaatag ttcctcatat tttgccgttt gttgagctaa
    49201 taccgaaggt cagctgattg aacaccgttt aagaaagagg tcgtgagcct gtcatttaac
    49261 tctgagtcac aagtaacaat ttcaaaaaac agcttctcat ctttgatgaa tatcgtgact
    49321 tgtggacgag gcgttgataa gtgaatcatc tttttgttac ctattttttc tgtaaccaaa
    49381 aaacgatgga acgttgtttt gattgccctt aatgaggaca gtcggaacag gtttgtcatt
    49441 tttatattta aatggcacaa atttttctaa ttatttgtca tttagcgctg aaaatttttg
    49501 ctatttatct aaaaaagtga taactactta agatgaagca gaatatttac gccatacggc
    49561 atacaaccgc gaaaaatata aaaaaaagaa aacgattgaa cgcgtttttg cagtcgcaaa
    49621 ggaaaagcat ggaatgcgct acatcaagta tcgagacttg gaaaacaatc aggtgtatac
    49681 gctgattgtt tttgctgcaa tgaatctgaa aaagttgtcc acttggcagt tggaacatat
    49741 gtcttcatat cttttattat acaaaaatag caaaagcacc agtctacact cttagtaaag
    49801 aggaaactga tccttttgtc tacattctta aagtacttaa actaagtact ttattttact
    49861 ctttaggatt gatacagtag catctatccc tttattaata atcttttatt tttttaaata
    49921 aagatgttgt ctccatcttc aggcactaaa actttttcgg aaattccttt ttctttattg
    49981 aaagacttta attcttctct tgacagtccc caatggttta cagcttccat atgaacggca
    50041 ataattgtgg aatctggtat tgctttatgc aattcatata aatcgtcttt ccccataata
    50101 agagattctc caactaaaaa atgattatct ccagcatttg ctactatgat ttctggatta
    50161 tactgatcaa tagtttgttt aacagcttca taccaaactg tatctcctgt aaagtatagt
    50221 gtcttctcag tcgaatgttt gaaaacaata ccgcaaacat tacctacata attcaagatt
    50281 tctcctctgc catgtttgcc ttttgtttta accaattgta tagattcaaa aactgtgtct
    50341 tctcgtagta cctccacatt tttaaaacca tatagtcgaa tttcattcgc atcattttca
    50401 tcttgcacaa ataattttat ttctttaggt aggacctctt tcgctatatc gtcccaatga
    50461 tctagatgta aatgtgttac aataacagca tcaataccgt tgataatatc ttcgactggc
    50521 attggcaaat caactagagg attcatttga tcttttcttg gtgatggaaa aggacctttc
    50581 gaaataaatg gtggaagtgt tcctttttcc gctaacattg gatcaattaa aaatttttta
    50641 cctccatagt ctaagatagc tgttgcatta cgaatgtgat gtatattcat aaacgttgtc
    50701 tcctttttgt tgatatgaaa tatttttagt ataattcaat tc
//
LOCUS       DADVXE010000016        41704 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.016, whole genome shotgun sequence.
ACCESSION   DADVXE010000016 DADVXE010000000
VERSION     DADVXE010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 41704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.016"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(12..617)
                     /gene="dhaL"
                     /locus_tag="KB913_000983"
     CDS             complement(12..617)
                     /gene="dhaL"
                     /locus_tag="KB913_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBB6819364.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(645..1655)
                     /gene="dhaK"
                     /locus_tag="KB913_000984"
     CDS             complement(645..1655)
                     /gene="dhaK"
                     /locus_tag="KB913_000984"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBB6819365.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(1630..2076)
                     /gene="dhaM"
                     /locus_tag="KB913_000985"
     CDS             complement(1630..2076)
                     /gene="dhaM"
                     /locus_tag="KB913_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBB6819366.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            2179..2499
                     /locus_tag="KB913_000986"
     CDS             2179..2499
                     /locus_tag="KB913_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBB6819367.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(2611..3480)
                     /locus_tag="KB913_000987"
     CDS             complement(2611..3480)
                     /locus_tag="KB913_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6819368.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(3576..4880)
                     /locus_tag="KB913_000988"
     CDS             complement(3576..4880)
                     /locus_tag="KB913_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6819369.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(4877..5386)
                     /locus_tag="KB913_000989"
     CDS             complement(4877..5386)
                     /locus_tag="KB913_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819370.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(5561..7696)
                     /locus_tag="KB913_000990"
     CDS             complement(5561..7696)
                     /locus_tag="KB913_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6819371.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(7779..9434)
                     /locus_tag="KB913_000991"
     CDS             complement(7779..9434)
                     /locus_tag="KB913_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6819372.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(9436..9750)
                     /locus_tag="KB913_000992"
     CDS             complement(9436..9750)
                     /locus_tag="KB913_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6819373.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            9920..10180
                     /locus_tag="KB913_000993"
     CDS             9920..10180
                     /locus_tag="KB913_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBB6819374.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            10194..10508
                     /locus_tag="KB913_000994"
     CDS             10194..10508
                     /locus_tag="KB913_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBB6819375.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(11238..11792)
                     /locus_tag="KB913_000995"
     CDS             complement(11238..11792)
                     /locus_tag="KB913_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBB6819376.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(11918..13847)
                     /locus_tag="KB913_000996"
                     /pseudo
     CDS             complement(11918..13847)
                     /locus_tag="KB913_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(14153..14869)
                     /locus_tag="KB913_000997"
     CDS             complement(14153..14869)
                     /locus_tag="KB913_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBB6819377.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(14870..16693)
                     /gene="glpO"
                     /locus_tag="KB913_000998"
     CDS             complement(14870..16693)
                     /gene="glpO"
                     /locus_tag="KB913_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBB6819378.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(16707..18203)
                     /gene="glpK"
                     /locus_tag="KB913_000999"
     CDS             complement(16707..18203)
                     /gene="glpK"
                     /locus_tag="KB913_000999"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBB6819379.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(18339..19799)
                     /locus_tag="KB913_001000"
     CDS             complement(18339..19799)
                     /locus_tag="KB913_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6819380.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(19789..21084)
                     /locus_tag="KB913_001001"
     CDS             complement(19789..21084)
                     /locus_tag="KB913_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6819381.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(21416..22093)
                     /locus_tag="KB913_001002"
     CDS             complement(21416..22093)
                     /locus_tag="KB913_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBB6819382.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(22123..23214)
                     /locus_tag="KB913_001003"
     CDS             complement(22123..23214)
                     /locus_tag="KB913_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBB6819383.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(23315..23749)
                     /locus_tag="KB913_001004"
     CDS             complement(23315..23749)
                     /locus_tag="KB913_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6819384.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(24333..25790)
                     /gene="ascB"
                     /locus_tag="KB913_001005"
     CDS             complement(24333..25790)
                     /gene="ascB"
                     /locus_tag="KB913_001005"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6819385.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EWVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(25787..27682)
                     /locus_tag="KB913_001006"
     CDS             complement(25787..27682)
                     /locus_tag="KB913_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6819386.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(27740..29515)
                     /locus_tag="KB913_001007"
     CDS             complement(27740..29515)
                     /locus_tag="KB913_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBB6819387.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(29565..31061)
                     /locus_tag="KB913_001008"
     CDS             complement(29565..31061)
                     /locus_tag="KB913_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6819388.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(31255..32877)
                     /locus_tag="KB913_001009"
     CDS             complement(31255..32877)
                     /locus_tag="KB913_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBB6819389.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(33205..34518)
                     /locus_tag="KB913_001010"
     CDS             complement(33205..34518)
                     /locus_tag="KB913_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBB6819390.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(34763..34987)
                     /locus_tag="KB913_001011"
     CDS             complement(34763..34987)
                     /locus_tag="KB913_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819391.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(35007..35429)
                     /locus_tag="KB913_001012"
     CDS             complement(35007..35429)
                     /locus_tag="KB913_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBB6819392.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(35571..36281)
                     /locus_tag="KB913_001013"
     CDS             complement(35571..36281)
                     /locus_tag="KB913_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819393.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(36299..36796)
                     /locus_tag="KB913_001014"
     CDS             complement(36299..36796)
                     /locus_tag="KB913_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6819394.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(36833..37285)
                     /locus_tag="KB913_001015"
     CDS             complement(36833..37285)
                     /locus_tag="KB913_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6819395.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(37420..38025)
                     /locus_tag="KB913_001016"
     CDS             complement(37420..38025)
                     /locus_tag="KB913_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6819396.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(38475..39095)
                     /locus_tag="KB913_001017"
     CDS             complement(38475..39095)
                     /locus_tag="KB913_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6819397.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(39097..39966)
                     /locus_tag="KB913_001018"
     CDS             complement(39097..39966)
                     /locus_tag="KB913_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBB6819398.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(39989..40396)
                     /locus_tag="KB913_001019"
     CDS             complement(39989..40396)
                     /locus_tag="KB913_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBB6819399.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(40415..41704)
                     /locus_tag="KB913_001020"
     CDS             complement(40415..41704)
                     /locus_tag="KB913_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6819400.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        11760 a         8982 c         7021 g        13941 t
ORIGIN      
        1 ttttattgaa cttaaggttg attgatcaca tctaaaagcg ttgaaaataa aatggcacta
       61 gaagcagctc ctgggtcgat atgtccgatt gcacgctctc ctagatagga agctcgtcct
      121 tttttagcta ccaagacttt ggtgtgttct tttgcctggt caatgatttc ttttgttaaa
      181 ttccctgcct tcaatgcctc tgtgactggc agccaaacat ctaacatcgt tttatcgtca
      241 gcttctgcct ttcctcggct ttgaataccc gctgttccct gctcgatcac ttcgcctaat
      301 ttttcttgag aatcaataga atcgacctct tttgtcgctt tcatcatgtt catgaatgca
      361 gatccgtata acggaccaga agccccaccg actttcgata tcatcgccat agagaatact
      421 ttgaatgtat cgctgattgt ttcaggatga tcggcttgaa aagcttcttc ataagctgaa
      481 acccctcttc ccatgttatt tccatggtct ccatcgccaa tcggggtatc tagatcactg
      541 agatattgtt tgttctgatt gattgcctct gcaaattgcg tgagccattc ttggatttct
      601 tgaacggtta gtttcatatt atcacccttt tatcttgaga ttttttacca tgaaatcgtc
      661 tgtacattgc tttctaaaga atctttccat tgtgtctccg tcaagtcgat cagtgttaga
      721 gaaagacctt gcatatctag tgaggtcata aaattaccga cttttcggaa aactacattg
      781 acgcctcttt cttccaacag agctaaaaca tcattcatga acacgaactg ttccatcaaa
      841 ggcgtcccgc ccattccgtt gactagtaca cctgcttctt ttggtaaatt cgagtaatca
      901 tctaaaatct tagtaacaag ttcctttgcc agtactttag aaggctgcat cttttctcga
      961 cgatagcctg gctcaccgtg gataccaaca ccatactcga tctcatcttc tcctagttcg
     1021 aatcctggtt tccctacttc tggtacagtt gctgctcgaa gcgctagacc gatcgtctta
     1081 gttgcctgta cgaccttttc tcccagttct ttcaactcag ctagggaagc accgtttctt
     1141 gctgcatcgc ccacgatttt gtgtacaagg acagtacctg caactccgcg ttttccagca
     1201 gtatacgtac tattttcaac ggcgatatca tcatctacga tcacactttc tacttcaata
     1261 tcgtccatag cagctaattc ctttgccata tcgaagttca atgcatcccc tgtataattc
     1321 ttaacgatca gcaaaactcc ttttccacta tcggcttcct taatagccgt ctgaatctga
     1381 tctggagttg gagaagtaaa cacatcacca agcaccgctg cacttaacat cccttcccct
     1441 acaaacccgg catgggatgg ttcatgtccg cttcctccac cagaaaccaa accaacttgt
     1501 tccgctttct gattcttggc tacaacacgg gaagattcta cacgatgaac aagttctgga
     1561 tagcttttta ctaatccttc cagcatttct tcgacaatat tgcttggatc attcatgatt
     1621 tttttcaatt tattcccatc ctttctttcc ggcattttgt gcttctgtta agatttgctg
     1681 agtatcatct gttataccgg cagtgatggc tgctgcaaaa gctccttcca ctaaaggcgc
     1741 atccaccaga tgataacgtt gctgctgctc ttcttccaac atgtcttttg ccagttccga
     1801 gttcaatacc gcgctaccga tatccgcaaa aacaaaataa ctagctgcat cgcttgattc
     1861 attgactgct tctacgattt tcatcgggtc tgatccgatc tcgccattta ttccgccgag
     1921 agaaaaaatt tgcacctctt cggatttttg catctgctca atcatttctt taataccatc
     1981 tgttactttt tgactatgag aaataagcaa aatacttttt ttcacaagaa tcttcctttc
     2041 ttttacatag ttgctaacga ttggtttcgc tttcattaat gaacaattca agtatataat
     2101 aaatttctaa ttttgggaaa atatgtgtag tgcttcttga agtttgttat actttaatta
     2161 aaagagagga gtgatcgaat gattacaaca acaacgaaca gtgtagaggg aaaagccgta
     2221 gtagcttata aagggatcgt ttttggtgag gtcattactg ggatccatgc atttaaagac
     2281 ttggaggcgg ggttgcgaaa tatctttggc ggccgctcaa aaagctatga aaacgaacta
     2341 atgggtgcaa gagaagaagc acttgccgaa atggccgaac gtgcaaaagc attaggagct
     2401 gatgcgatca ttggcgtaaa aatggactat gaagtattag gcagcgacaa tggcatgctg
     2461 atggtcacat gtagtggaac agctgtctcc acgagataag taggggacat ctgttttaat
     2521 aactaaagag agatgggaca tgtagtggca ctcaagaatt agatttttca gtctaacttc
     2581 gaggtactct accttcccat cctctctttt ttatttcttt ttgcggatga ttccgtaagc
     2641 tgctgcgact aacacacccg cccctgctaa ggaataactg acagaagctg ttttttcatt
     2701 tgtttttggc aaagtctgac ttgttgattt ggatggctct gtcgtttgct gaactgtttc
     2761 tgtcgtgctt ccagaggtca ctgatttttc tcctgccgaa tgcaaaatat cttttattcg
     2821 ttggaaacta gctgctaagt cagctttttt tgcttcaaaa tcattagcaa ctgtttgtgc
     2881 ttcgctgatc tttccgtgga ttgcttgact ggccgctgtg atatccgctt gagtttgact
     2941 tagctttcca gaagctgttt gagcaacctg atttaattgc tgattgaatt cttttgcttg
     3001 ttggatcttc ccgtcaagat ctgtttggac agcttccgct tttgctttcg cttcggcaag
     3061 ctttttctca agttgtgcac ggtcatttcc cactttattt ttaagatcag ctaaatcttg
     3121 atcgattgct gcttggtctt ctttcaattt gttttttgca gcttctaatg cttcttcgag
     3181 ttcttttctt ttattttcca agtcttgcaa atgatcgatt tggtcagaag aggtagaact
     3241 atttattgat gtatcttctg aagatgaaat cgtttctcct gaattatctg tcggtacatt
     3301 ggaagtcatt tctgtttccg aggcaccgtt ttcagcacca gaagagctta tggttgttga
     3361 aggttctgtt tgagcaggtt cagaagtttc cgcaaaagct gtctgtccca ataagaaaat
     3421 actggaaaca gcaattggcc agattaacgg cttcattctt tttttcatca cttttcccat
     3481 ccttactact ttttaactaa tttcttatta taagcaaaaa tgtttggaag aaccataaac
     3541 acaacaggct gtttgtctaa aaaacggtgc atcttttatt tttttgtacg ttccgggctt
     3601 ttccatgtcc cgcttccata acctaaaatc gttttgactg ctggaatgaa agtcgtcacg
     3661 atcgttatcg cgttcactat ccagaacaaa agcatatata gtggtgcgaa aagaaggtat
     3721 ttcaattttc ttcgtcgatc atctacaatc agcgaagcta gcaactggaa aaatcctgcg
     3781 accatttcaa agcagatgaa cacaaaactg aatgtaaaag taatataaat ctgttcgtag
     3841 tttccttgat atacataatg cccgattaat ccagcaaaaa gaactacgga aatacaaaag
     3901 aatattgacc agacaatact caatgtttga tcaatgaaga tgatcgttct tccaatatgt
     3961 ttaaaaggat ggagcatcac ttttttgaaa ttcgtcagcc agacttctgt tccacctttt
     4021 gcccaacgtt ttctgtgtcg atatagcatc ttcaacgtca caggtacttc catgaaaaag
     4081 ataatctcag gagcaaaaac agataaccag tcatttaact gatgatccca agcaatactg
     4141 atgtcttctg tcgctcgatc ttgtctgaat ccgcccacat cgatcaaggc ttcttttcga
     4201 tacatcgtat ttgctccact gtacgcataa agaccaccga aaacagctga ctgtgttcgt
     4261 ttaatgatgc ccacgatact tgagaattca accgtttgag attttgcaat caatttggta
     4321 cgattttgga catccatatt tgcagtgacc gcagcaatat gtcttgcacc agggcgaatg
     4381 aaataattca catacctaat cagtgcatct ggctccggta ccgtgtctgc atcattgctt
     4441 aaaatcaatt tcccttttgc aaaggcaagt ccgatattaa acgcgtgggc ttttccttta
     4501 tttttttcga tccgaaccac acgaagatta gcgtattttt tcatcagtct agctaatatt
     4561 tctggtgttt ggtccgttga accatcgtct gtcactaata cctcatagtt gtgataattc
     4621 aatttcgtca tcaaatactc gattgtatat tcgatcacaa tttcttcatt atgggctggc
     4681 accatgatcg tgatgaacgg ttcgacactc aagggaacat ctacccattc tttttgctta
     4741 tgtttgtata aaaacacata acaccagaca ccaataaacc atacaaatcc gcctaaaatc
     4801 ggataagaaa cgagaaaaaa atacataata gacaaacaag tatctaagaa taaattacct
     4861 gtatgggtga ttgagatcat ttcagttcca ccccattttc tttatacaaa tctgcaatga
     4921 atgtcgtatc tagatttttc tcttcggaga cagaataaaa acggaccgtt tctctctctt
     4981 cttttgttcc aaaacgttcc gtatacactt cttcaagtaa ttcttgtctt tttttcaatt
     5041 tttcatcttc atattcaaaa gatttattta cttttttgta tagatttcga ttgttccacc
     5101 tagtcaatac aaatgaggta atcaggaaac tgaaaaaaat caatacaaaa aagccgatta
     5161 agaaatacag cattttcttt tctgataaaa aagcgtacaa ggaaaaatcc ttggctcttt
     5221 ctggtctcgt taatgggaaa aagacccata taaaaggaag aacaacgatc atccatccta
     5281 aaagagccac taacgtttgc caaatcttta accagtaatt accttttgaa aaatacttat
     5341 ctttcaccaa aattgatgca acttcttctc ttgttacttt tttcatatcc tcacctcacg
     5401 tttttttgtt acgacgtagg agtttaccat acatttcatt tcttttcaca taaagtgttc
     5461 ctaaattttt cctaagaaaa agaacaaaac atttctcatc agcaaatgaa aaatattttg
     5521 ttctttttat cagttgttct ttttattttt tatctcttaa ttatgttgct ctttccaata
     5581 cgacaatgct tttcattcct ctagatatcg ccgtgtacat ttgtctgcgt cttctttgct
     5641 catctccatc gttttcaaat ggatataaga ttacatgatc aaattccagt ccttttgcta
     5701 gactcaaagg aatgatttgg cagttttcta atccatatga atttttttta atcgattctt
     5761 gtagcgtttg ggtttcctct tctgtttggg tgataactgc cgctttttct ccttttagag
     5821 aaaccaaaat ctcagctagt attttcaaca attcttcaga ggatcgaaaa gagcggtatt
     5881 cgggttcttt tccttgcggt cggatcgata cgatgtcgat cttctcttga tccacagcat
     5941 aggttttgaa aagctctgtg attgctccgc tagaacggta actatttcta agatcatacc
     6001 gatggatcgg cagatggtag tcgtcgaaac aacgcataat atcagcaaaa gtagtggaag
     6061 aattaaagat tgcctgattc tcgtcaccta ctaaagtaaa gtgagttttt ggaaataatt
     6121 cgatcaatag acctaattgt gccagggtat aatcttgtac ttcatcaatc aatagatagc
     6181 gaaatgctgg tacatttacc ttttcaacaa gtaaatgacg aatagctaat ataatgactg
     6241 cttcatcaac agtacgtgtg ggttgccaag cataagctga gccatatcgt ttttcataaa
     6301 ttctttcaaa caactgatgc tcatccaccc atgccatttc ttcgatttgt ctggttattt
     6361 ttcgatattt tttttgtaaa agtttccttg cataagctac aatactttgt tccgaatcat
     6421 cagaaatcaa tttaccgaat aattccaact gcctatcttc tgtcaacgag agtacctgat
     6481 tctgcacagc aggacttttt gcttgtttca aaagatgatt cttccattcg ctcatcagtg
     6541 cctttttcgt tgcttgaagc ctatcgatca atttaggatg agcaggaact ttctcatata
     6601 ttttttcgat cgttttttta gaaaggactg tttttccatt tttagtaagt ccacggataa
     6661 aattcggatg atctaaaaac aaaggatctg attgttttag attatcgata aactttttgc
     6721 tacgcaaacg ttctgtctgc tccgatacat tttctcccgt gatacgtttg aaataagcct
     6781 cttcaccttc tatttcctct gctgaaagct gtgaaaccag ctgtatgatg gttagattca
     6841 gtggatttct ttcacctaat gatggtagga cattcgaaat atagtcgata aaccgatgat
     6901 taggtgatag aatcagcaag tcatcggatg tcatcgtatc tcgatataaa tagagcagat
     6961 acgcaatacg ctgcatgata gcagaggttt taccacttcc tgctacgcca tttaccaaga
     7021 tattttgact tttcacatcc cgaatgattg tgttttgttc cgattggatc gtagcagtga
     7081 tagccttcat ttcattggtc tcatcttggc ctaagacttc taataatacg tcatcttgaa
     7141 tagctacaga cgtatcaaaa aacttgacca aacgatctct ttccaaaaga aattgtcgtc
     7201 tttctttaat aaccgtatcg attttatttt gacgaaccgt ataagaagat ggaccaatca
     7261 tgttattgta aaaaagttcg gcaattggtg aacgccaatc ataaacaaga ttttcatctg
     7321 catcatctgt gaaatttgct gtaccgatat aaaaggattc ttttggctca ttatccagaa
     7381 agtctacaac gacttttcca aagtagggac ttttcaataa acgttcgatc tttgctagct
     7441 gattttctgc gtttttctgt ttgatattca tctgatcgat ttctctattt ttcatttcaa
     7501 tcatcgaaaa agtatccagg ttatctaagt aactgtcaaa attcaatcga agctcgccag
     7561 ccatttcttt caacgactgg tttccttcta tttttgccgt atccatcgat tcccgcagtt
     7621 cgtttttttt atcaattagc ttttgataca cgttcttcag atatgcttct tctaactgtt
     7681 tttgtgtgtt gaccatacac attctcctct ttttttaaag tggtggaacc gattagttta
     7741 cctcttttaa gagtcgaatg caagcttttt aacgagtatc atttgttagg atatatcagt
     7801 tcttcaggtc ggacagtttg atataaagaa aatgcaccat caaggttttt tacgtggtag
     7861 ccagactgct tcaagattct ttccgctaga tagctacgta atccgctatg acagctgacg
     7921 atatattctt gttggctgtc taattcattt aatcggtccc gaagttcatt caaagggata
     7981 tgtttggctt ccttgaattt gcccttttcc aattcttctg ctgttcgcac atctaataaa
     8041 atttttcctt ttgctagttc tgtcggcaat tcatgccatt gtacggtttc actaagccct
     8101 tctgcaatgt tcattgctgc atatcctagc atgtttactg gatctttggc tgagccaaat
     8161 ggcggtgcat acgtcaattc taattccggt aaatcgaaga tcgtcaaatg ccctttgatt
     8221 gctgttgcta aaatatcgat ccgtttatcc acaccttttg ccccaacacc ttgtgcacca
     8281 taaatctcgc cagtctctgg atggaagatc aacttcagta aaatatctgt tgcttctgga
     8341 taatagcttg catgatcttt tcctgataca tgaatgactt caaaagacag ttcgttttct
     8401 ttggctgttc tttcacttaa accggtggat gcggcagtca ttccaaacgt tcgtataatt
     8461 gctgttccaa taccgccttg atttcttcga gaaattccgg aaatcgtgtc cgcaacttgt
     8521 ctaccttgac gattggctgg tgaagcaaga gaaataagtg catcttttcc agtgatttgc
     8581 tgttttacaa cgatagcatc ccccaccgca taaatatcag gaatattcgt ttgataacgt
     8641 tcgtctacta ggataccccc gcgtatgcct aattcgattc cagcggtcac tgctagctgg
     8701 ttatcaggac gaacaccaat ggataaaata actaaatcag cagggatggt acgcccatca
     8761 tccagtcgca atcgtttccc gtggtcttca aatccagcga cagcatgaga agtaatcact
     8821 tctactcctt gatgagacaa ttctttttct ataaaagctg ccatttcttc atccagtgtt
     8881 ggaagaatat gtggtgcttg ttcgatcacc atgacttcta aacctcttct ttttaggttt
     8941 tctgccattt ccaatccgat gaatcctgca ccaacgatca cggcacgctt tggctgtttt
     9001 tctaatgcat gcatcacttt atcgatatct ggtacatttc taatagaaaa aacattgtcg
     9061 gcttctgtta tccctggaat cgatggaaca actggttttg caccaggaga taaaaccaat
     9121 gcatcgtact gttcaatgtg tttttgaccc tcatgtacga cttctaccgt tttgttttcg
     9181 ggaaagatgg ctgtcacttc atgatttgga cgcacatcta aacaaaaacg agcggataat
     9241 gattctggcg tttggacaag aagattttcc cgttcactga tttctcccga aagataataa
     9301 ggcaagccgc aatttgcaaa agaaacatac ggtccttttt caaaaacaac gatttctgca
     9361 tcttccatta atcggcgaag ccgtgtagca gcagacattc cacctgctac acctccgaca
     9421 ataacgattt tcatcttatt tccctcctac tgttcgatca aaccattgat tcatgccacc
     9481 acgtacattc actacatcat aaccagattt ctttaattct ttagctgctt gtttactcct
     9541 catccctgat tgacaaatca catagacggt cttttctttg tctccatcat atctgtttat
     9601 actttgtaat ggaacatttt tagctccttt tatatgcccg ccccggtatt ctgcaggtgt
     9661 tctaacatca agtaacgctg gattttccaa aagcttttcc tttaattctg ggactgttat
     9721 cgattttatt gattgaaata gcaaattcat tttctgcacc tcatttacat ttttataaat
     9781 acctcatggg gtatattaaa caggagcttt attaatatgt caaccagaat gactcttcat
     9841 ttttttcact actttttata tttgcataaa ataccgataa ggggtattat ctaattataa
     9901 aaatagagga gaatgtgtta tggagattga taataaaaat atcctgaacc gtttgaaacg
     9961 tacagaggga caaattcgtg gtatccaaaa aatgatcgaa gacgaaaaag aatgtatgga
    10021 tgtcatcact caattaagcg ctgttcgttc tagtattgat cgcgtaatgg gcatgatcgt
    10081 tgcagataat ctgaaaaatt gctttgagaa acctgatagt aatccagaag aacaagcggc
    10141 taaactagaa caagcgatca agatgattat taaaaagtaa aggaatgatt tcaatgaaag
    10201 tcgttttcca tattgatgaa ttagaaaaat ggtcagaaac agggaaaaac gtaaaaaacc
    10261 tgataaaagc ttctccagaa acgacgattg tcgtatctgt aaatggcatc gcgattaccg
    10321 gttatctaga ctctgccaat gcagaattct tagatttgca aggagtcgtt tttcacgctt
    10381 gcgccaatgc tatgcgtgct aatcatattt cagaaagttc tttacctgaa caagtaatcg
    10441 ttgtaccagc aggtgtcctt gatttagttg aactgcaatc ccaaggttat gcttatatca
    10501 agccttagtc agtagaggtt gcgacagaag tgatcagctt caagaaattt cggcttattt
    10561 ttcgaagaag ctacttctgg aaaaccgtga atcaaaggtt gtgaaaacgc tgtcctgcat
    10621 caagtaataa gaacagccaa acaaaaatag cttctcatat ttttcgtttg gttgggctta
    10681 ttaccgcaga tgcaagcttt tgaacaccgt ttaaggaaga ggttgtgaaa tcagcggttt
    10741 gacctaagta ttagagaaaa aaacgggaaa atagctcctc atattttgcc gttttttgag
    10801 ctaataccga aggtcagctg attgaacacc gtttaaggaa gagattgtga aaaagtcgct
    10861 tagtttcgag tattaagaaa aattttgtga aaatggattt ctacattttt gcataaattt
    10921 ggcttaatac cgagaaactg gcttttgaat accgtttaag gaagaggttg taaaatcagc
    10981 ggtttgacct gagtattaga gaaacaaacg gaaaaatagc tgctcatatt ttgccgtttt
    11041 ttgagctaat accgaaggtc agctgattga acaccgttta ccaagaggtt gtgagcctac
    11101 catttaactc cgaatcacaa gaaataattt caaaaacaac ttctcctgtt tttggttcgg
    11161 ttggcttatt atcgagaagt agctactggg agtctattta tcaaaaaaag gaatgcgaca
    11221 taggtcacac ccctttttta ttttctttga aacatctttc ggtactcgac agcatacaag
    11281 acaaaagatt gtaaaagacc gtaagtgatg acggcaaaaa tgactctcac ccacagcgtt
    11341 ggtaattctg ggaaaagcag caaaaggatc atgccaacat agatgacagc agtcgctact
    11401 ttgccatacc acttcgctcc acttaatttg atatttttag atagcccgat taatccagct
    11461 acaaacataa agccttcttt tatcaagaat agaccaaaca acagccaaag ccacggtcga
    11521 taccatgcca tagacaaaat cagaaaaagt tgtgtcaatt tatctgcaaa cggatcaagc
    11581 accttcccta agtctgttac ctgattatat ctccgagcaa tgaccccgtc tagataatca
    11641 gacaaacctg agacaacaat gaccgctcct gctatataaa atgactgtct cagcacaaaa
    11701 taaagataaa tcggcagcaa aaaaatacgg aatatcgata aaagattcgg aatcgtttgt
    11761 atttctttac gccagtctgt gcttaatttc attttatcgc cctacctcct cagcactctt
    11821 ttctttttat tttagcttac acggggaata aaaccaatga tttcactgtt tttatttttc
    11881 tttacagaca ctgatattat gagctaattt gagataatca cttgctgttt tcatcgttta
    11941 ctcttctttc ttcctgtcgt ttgcgcattt cttttactag tactttatga gctttttttg
    12001 atcctcgctc taggtcacgc tgccgtttac gtgttttata atcgataaac agactgtcta
    12061 aatcgtaacc tgtcgggtac agatcttctg ctgaacgcac cagacgaaca cgctgacgag
    12121 gcacgtggat tatttttttg tctaaatata catcaatcgt atcttcacct atatcttcat
    12181 aaactaacgc ttctttttgg tattcattga caaatatccg atcacctttt gcaaagagct
    12241 gacgttcttt tttattctcc ttcctatttg taactgctgt cttaggaaga aattcttttt
    12301 tctgtgtccg ataggctttt tccgccaagt aacgctctgc ttgatggatc aatttcatcg
    12361 acatatccat tttatgagca atccacaaag cttggctttc tcctgtttct tccaacccgc
    12421 aactgatatt taggacgaag tgcttcccga tcgaaagcca tagcagccgg cacaaaatct
    12481 tcatgatctc cggcgaattt cttgatttct ccataatggg tcgtggcaat gatcaatgcc
    12541 ccttgctcat acatagattc catgattgcg atcgctagtg cagccccttc atttggctct
    12601 gttccactgc caatctcatc taaaagtacc aacgtattcc tttttatctt tttcaaaata
    12661 gcagcgatgt tttgcatatg accagaaaat gtactcaacg cattttctaa attttggtgg
    12721 tcaccgacat cgacgaaaat ctcatcaaag acagcaagct ctgtcccttc ttttgccgga
    12781 acttgcatac cgaacatcgc catcaaagtc aataaaccga ctgtcttcaa cacgactgtt
    12841 ttgcctccgg catttgctcc ggtgataatc aagcctcgat agtctttacc gatttcaaca
    12901 tccaatggta ccgcatgctc aggtaaaaat ggatgtctgc cttgcttgat aatgatatgt
    12961 tccgatttat tgattctagg tgtgcttcca ttgatttctc ggctaaattt tgcccgagca
    13021 aagatgatat ctaacaccgt gatcgtttcg atcaataaat cgatcacttc ttcgttttct
    13081 gcgatagcac cagtcaatgc cgccaggact tgatattctt cactgatttc ttcagctttt
    13141 aacaactgat agtgttcatt caatttagaa atcacagttg gttcaataaa aaccgtcgtt
    13201 cttttatttg attcatcgat aatcgttcca tctattttat ttttatagct ggctttgata
    13261 ggaatcgtat agtattcgcc tttttgaaca atcattgctt cttggatcat ttctttgttt
    13321 ttcggatgac gcaagaattt cagtaatttt gactggattt ctttttcgat tagttgtaat
    13381 tgtttgcgta ctttacgcaa attacgtgac gcgtcgtcac tgactttatt attttttatt
    13441 ttctggtcaa tcaactcttc tacatttatc aaatcaggaa gatgtttgct ataagcaaac
    13501 aacaagggtg tctggtattg attcttatca aaaaactttg tgatcatccg actgcttcta
    13561 agaaaatccg catattcgat caaatcggtt ggctgcagaa tcaacccttt tttgacttgt
    13621 tctgtcagtg catcgatcct cggcaacccc ataaatggaa catgctgact gctttctaag
    13681 atcaagcgtg cttctcttgt ttcttcttga cgatccaaga cagtttgtag gtttgtcgag
    13741 accgtcatat cgctgattcg ttttttgcta tagtttccaa ttgctcttgc ttggatttcc
    13801 tttttgatcc gatcaaattg taattgacta atcatttcgt tgtccatatt ctctcctttt
    13861 cttgaagaga tacctgtccc aaaataaata agggcctaga gataaataaa aggatagaac
    13921 acagcttaaa aaagtcatgt cctatcctta ttagaataca aagatattgt tttcctgaca
    13981 ggtaccgttt cataagcaca ccaaataaac tttgtttatt ggctattcga cttactgatt
    14041 agataccagc tacactcaca aaacataccc cattcttcta ggtcttattt attttccact
    14101 taactatagc aagacacatt ttggttgtca aactttagta tgttttatag atttacacca
    14161 ttaatgaata gacacctacc gcgataattg ctccgatcat tggacctgcg attggtaccc
    14221 atgaatatgc ccaatctgaa gttcctttat tagctattgg caataccgca tgtgctaatc
    14281 gaggaccaaa gtcccgagca gggttgattg catatcctgt tggccctcct aatgaaagac
    14341 cgatggctaa gatcaatcca cctacagcga atacgttcgt tccaggtgca aattcgtttt
    14401 gtccaaaagc tagcaaccca agaactaata caaatgtacc aattaattct gtgatcacat
    14461 ttgctggata attccgtata gcaggacctg ttgcaaacgt tcctaaaatc gcgctttcat
    14521 ctttcgttgc attccaatgt ggcaaataag aaagccaaac aagaatggcc cctgcaaaag
    14581 ctcctaaaac ttgcgcaatg atgaaaggaa cgacaagatt ccaactaatt gcccctgtca
    14641 tcgccatagc tagagagact gcaggattca aatgagctgg gcccatgaat ccagaaatat
    14701 agacagccat tgttacagcg agtccccaac caaatgcgat gacaatccag ccagaagcct
    14761 gtgctttact tttgtttaaa ttcacagccg cacacacacc atctccaagc aaaactagga
    14821 tcagtgtccc aataaactcc cccatgattt gagtcatatc actgttcatt tatttctccc
    14881 cctttagttc ccgcagatct gattctgcaa tcaatgcttc taaacgttta gtctgttgcg
    14941 ccttctcctc ttctgtccat tcaaaatatc cagcaattgc atcgatcaca ggttgcttga
    15001 tctcatcaag ctgatctcgt tcaaacaaca gatgatttgt acgacgaatg agataatcgc
    15061 ctggggccaa aaccatttct tcttctaaac cataacgtaa ccgagctgac tcagcgagac
    15121 tcaaaccagg ataaggtgcc atttcttttg ctaattcaaa gatacgtcgg gcattagtcc
    15181 cgtaaaaatc agcgatataa gtagcatctt cttcctctaa accggctgct actccttctt
    15241 ttgctaattc tgtcactgtt tcttctaatt tagttggatc gaagtttcca cctgaaatct
    15301 gatatttttt agagtcgatt tctttcgtct ctattccgta ttcttctttt aataattggc
    15361 gtatcaatcg caaagctcct tctgccatct tacggtaatc ggtgattttc ccaccagata
    15421 aagtcagcaa accatctggt tctctttcta aagaactacc tctggaaatc gtagaaggtg
    15481 ctttttcatc acggctgttt tccaaatggt tcaacacgtc ttctacttca gcacgagaaa
    15541 ctttgttttc cttatattca cttactgtat cgacaacttt attgaagctc ttgtctgaaa
    15601 tcgatccatt atctccacca ttgtaatcag aaccagaatt accaatcaac agtggacgaa
    15661 gtcctgccca gcttgcttcg atatcattca atgtgatatt tgcttctgga tagcgatgat
    15721 tgatcacatc caatagataa tctacatctt cttgtgtgac tttcggatcc gtaaaatctc
    15781 cttggtaatc cgtatctgtc gtaccaaagt aagtcttgtt ttctcttgga atagcaaaaa
    15841 ccatccgccc atcttgcttt cctgtatcga agtatgtggg ttgcggtaca ggcagttttt
    15901 tcgcatctac aactaaatgg atccctttag ttggacgcat tttaggagag actggacgcg
    15961 taaaattcaa gtttcgtact ttatctaccc aaggaccact cgtattgatc actaattttg
    16021 ctttgatttc gatcacttca tctgtcagca ggtcacgagc tttgacgcca acgatttgat
    16081 cgccatcata taaaaagcca accgctttca ttttacttac tagataagcc ccatcttcgg
    16141 cagccttttt gatattatca atcactaaac gggcatcatt gttgcggaaa tctagataga
    16201 cacccgcgcc ttttagccct tcttttttca aaaacggttc tctttccaat acttcttctg
    16261 gtgtcagcgt ataattctca tatttggttc ctgtcacatt tgccagtttg tcataaaggt
    16321 ccattgctac tttgaccgag aacatattga aggttgttgc tccttcgccc tcatagattg
    16381 gcaaaagcat tggatctggt tttgggatgt gtggggcaat actttgtacg actgcacgtt
    16441 caccaactgt gtcagctact acttccacat caaatgtctt cagataacga ataccgccat
    16501 gaacaagttt ggtcgagcga gaggaagtcc cttctgcaaa atcctgcatt tcgatcaatc
    16561 ctgttttgat tcctgatgct gctgactgga ctgccacacc ggcaccagtg attccgccac
    16621 cgatgatcaa cagatccaat tcttcttgct gcattttttg aatgctatct tgtcttgtct
    16681 tgtttgaaaa catatggatt tcctccttat tcaaatgctt gggtagcttt tactgctttt
    16741 ttccaaccgt tgtaaagttt ttctcggcgc tcttcctcca tttgaacttc aaatagcttg
    16801 ccagcttcat aaaattcgcg gatctcgtct gtatctttcc aataaccgac agctaatcct
    16861 gctaaaaatg ctgcccctag cgccgttgtt tccaagtttt ctgctcgttg gatcggtaca
    16921 ttcaagatat ctgtttggaa ttgcatcaga tattcattgt ttgctgcacc gccatctact
    16981 ttcaatacag gaatcttgat tccagtgtca tcttgcatcg tatcgatgat atctctcact
    17041 tgataagcaa tcgactgtaa agtagcttta atgatatctt cttttgtcgt accacgtgtc
    17101 aagccaaaca tagcccctcg tgctgcctga tcccaataag gagcacctag cccaacgaat
    17161 gcaggaacaa cataaacctc atcttcgctt gtagagcgtt tcgctgcgtc ttctgaatcg
    17221 ctagcttttt gcaacatttg aagtccatct ctcagccatt gaatcgaaga accagccaca
    17281 aaaatacttc cttctaaagc atagtaaacc tttccattta tgccgtaacc aattgtcgtc
    17341 aataaattat ttttggataa ttgcggtttt tcaccggtat tcatgacaat aaatgaacct
    17401 gtaccataag tattcttgac catgcctggt tcgaatgcca tttgtccgaa taatgcggct
    17461 tgctggtctc ctgccatccc tgaaattggt gcttcgcttc cataaaaatg ataaccttgc
    17521 gtataaccat aaacttctga gttagaagtg acttttggta acatcactcg aggaatattt
    17581 agtaaatcta aaatctcctg atcccaatct agctgatgga tattgaacaa catcgtccga
    17641 ctggcattcg agtaatcagt aacatgtgct tgtccatcgg tcagtttcca tactaaccaa
    17701 gaatcgatcg ttccaaacat caattcgcct ttttcagctc gttcttgcgc gccttctaca
    17761 tgatcaagaa tccagcgtat cttcgttgct gagaaatagg catcgatcac taaccctgtt
    17821 ttttcgtgga aaaattcttg atagccttca ttttttaagt tatctgcaat tccagctgac
    17881 tgtctggatt gccaaacaac tgcatgatag attggacgtc ctgtatcttt ttcccatatt
    17941 actgttgttt cacgctggtt cgttatgcca atcccagcaa tctgatttgg tttgatccct
    18001 gattcgatga acgctccggc aataactgac tgtacagaat tccagatttc atttgcatca
    18061 tgttccaccc aactttcttg cgggaaatat tgcgtgaact ctttttgaga actgccgatg
    18121 tgtcttcctt tcttgtcaaa gataattgct cgtgagctag ttgtaccttg gtcaatcgcc
    18181 atgatatacg ttgattctgt cattgtgatt ccctccatta tatgcaaacg ctttctttaa
    18241 ctactcttat catactactg ttttaaaaaa agaaactgtc aaaattttat tctttttttc
    18301 tttttttgac agttttttat tatgaagcta ttttttaatc aattcttttc ttttttcagc
    18361 gtctctattc ttcttttcaa tcgaataatg tcgtaaggtg acgcaaattc tgacagataa
    18421 tattcacact gttttttgtt tctctggcaa aatgtgatca ccaaatcata ttctttacct
    18481 tcttcataac ttccaatctc aataccgccg attcccctca gttctctgat cagatattgt
    18541 tgaaaagcaa tacgataaat cggcagactt tctaaatcga ttccaatcac tactggtttt
    18601 gcaatataaa aatcgatcat caaaagaaca ttggcatact ggatcatcag gtaactaagc
    18661 tcactatctt cagctctttt cctcggcaat tgctgcaccg ctgtttcctg taatttcgcc
    18721 agtaactgtg ttaaggaatg cccgagcatt ttctgctgct gttccaaaag ccgatcacgc
    18781 tcatagactt cgatctttcc aacaaagaaa aaccattcat tgttgatctg ggaaatttgg
    18841 tagcctactg ccttttcttc tttgattttc aaacgacgag gacgataatg ccataacatc
    18901 gtttcccgaa tgtaagtatc taaaacagcg gttggtaact ttttgctccg tgtcaaatca
    18961 tactgataaa atatttcttc gtctactatc gaaaaagaaa caaaaaagct gtaaaacatc
    19021 attgtttcgt atacattcag ttctgctgct gttcgactaa gatgcatcac gatgattgga
    19081 tcgattgctt gataaagccg gtccgactga tagagtaatt tcttttcttt caaagttgcg
    19141 tacgtacttt tttcattcaa tagtcttttt ttcgtaatcc cgagccagca agcaatctgt
    19201 gcttctgctg atgccgtaaa cgttgtttct aatacacggt ccaatcctag aatgaacggt
    19261 cttttttctg gtgtattttg caaaaaaagc ggtcgctgat cttccgggat atattggaat
    19321 agttcataat aaaaatatcg tatctgtagc tcttctccgt ataattgacc gtttttgatt
    19381 tgtaatccaa attcctctaa gagctggttc aattctttga tctttcgaaa aacagaagac
    19441 tcactgatat taaacgctgt cgctaatcga acgatggata cttgctgatg ttctaataaa
    19501 tagacgagca tcttaaactt caagctttcc tgcaataaaa acaatagaat tttttccaaa
    19561 cttacatctt cgtccaacac aagcagcgcc tgatactcat ttcgctgtac ttctactttt
    19621 ttttccatca ttcggccaat caattcaata tcttccaaat attgatcaaa cgaggctttt
    19681 gacagttgga catgctctct caaaccattg atagaggctg ttcccccttg cagaacaagg
    19741 tttcgcaaaa tcaggatctg taactgctct tttctttcta ataatgcttc aatcttcata
    19801 ggcagtattc gccacctttg accacaccat atctggcaca cggtattctg gctggaaaaa
    19861 tagctcatgt tcttctaact gttcaaacgt ccatccttct tctactgcaa ttgtcagttg
    19921 gtcaagaagg tggaacatct cttttttgct ttggagctgt gctccaagaa tctttttttc
    19981 agaatcaaat agaaatttga gtttaacttt gctttgattt attgctgtaa gcttgtagtc
    20041 tacgtatcct gtttcaattt tttggggata aaaaatgctc tcttcttctg tcaaacctac
    20101 gcttcctaag aaatagccaa accactgatt gccgactgga cgataggttc cctgatcctt
    20161 tgtctgtgag ccactaattg tcttgctgac atttcgtgct gtacggacag cgttatttac
    20221 tagagaaaca tacatttttt catttgttgg acgaaaagtt acttggatcg catcgccaat
    20281 cgcataaacg tctttttgag acgtttgcaa gtagtcatct acccagatcg ttccatcatc
    20341 attcaatgtt aattgttctt cccacatctg attgtcggga cgagaatgat tagccagcaa
    20401 aacaagatca tagttctcct ttcttttttc cgtctctaca atagcggttt cattttcggt
    20461 caaagacaca acttgttctt ctaaaaaaag tgaaagccct tgatttttca tttcctttac
    20521 taacggttct gtcatttcag gatctagata acgaaaaaga attgactttc ggctttcgta
    20581 aagatggatt tgtttttttc ttgatgccaa cccttcagct atttcgattc ctgcttgtcc
    20641 tgcaccaata attgcaattt tctttgcatt catgatcttt tgctgaagag ccgttacgtt
    20701 ttgtatcttt ttaactgggt gaataagcgt tgattctgca gaaatatttc gaaacttttg
    20761 atttgaacca gtcgctagaa tcaaacgatc aaaatccaat ttttttcctc ctgctaaaac
    20821 gacttttttt tctttcaatc ctattactgt cttttctgtg taaacatgga ttcgatagcg
    20881 gtcagtcagt tcttctttcg tgatccaaga aagttgtttt tcactggtaa cctttccttt
    20941 taatatcaaa ttgaacccgc tgggaatcca tcctaacttc gattgctttt caatcaaata
    21001 tatttcactt gttggcatca attggcgaag ataaatagcc gcatgaatcc ctgcaaacga
    21061 cccgccgaca attacaatgt tcatctgcat tcctctttct tataaggtgt tctactgcta
    21121 acttctcaat cagaaaacac agtattcata actcgctttc aaccttatga tacatagcga
    21181 tgcagcagaa tcaaccctct ccatcatacc gtgttctagg tctgcttctc aataatgtac
    21241 tagtggacct aattgaagag tatcatttct gaagagatgt ttcaaaaaat gtactcttat
    21301 aaaagaaaaa aactcgcctt ttacgtacct ctgtccaaat aggaaacaga aaagaacgaa
    21361 aagacgagtt ttagcgtgtg taatgtaata gttagaatag acacatcatt tatttttaat
    21421 tctttaatgc ttcaacaact gcttcgccta attgatgagc agattgagga ttttgccctg
    21481 taagaagccg cccatcaatt tgaaccactt ctgaaaaagc tgctccagac tgatagtttg
    21541 ctcctttttc tttcaaagca tcttctgcta agaatggtac ttcattcgtt gtaccatttg
    21601 cttcctcttc ttcattactg aacccagtca ctgtacgtcc agctaaaata gattttccag
    21661 actcatctgt aactggcaac aatcctacaa caccgtgaca aacagctgag accagccctt
    21721 catttcgata gatttgtgaa gcgactttcc caagatctat tgcttctgga aaatcccaca
    21781 ttgttccgtg gccaccagca taataaaccg ctgcataatc atttgcatcc acatcatcag
    21841 gacgtaaggt atttcccaag gcccgatttc tgaaatcttc atcttcataa taggcccaat
    21901 cgatttcatc catattcaaa acactttgcg gttctaaagg tacatatccg cctttaggac
    21961 tgacaaaatc tgcatcgatc ccatttttta ctaatacatc ataaaaatga gtcagttcac
    22021 ttaaccacaa acctgtagga cgctcgatct tttcgtactt ttctacattt gttaatacga
    22081 tcaatacttt cattttccca tcctctttct ataaaaattg cgttattgat aacgtgcttt
    22141 caagaaatta tataatgggc ttggcaaata aagctcttta tatgcttttt caaaaggttt
    22201 cgttacaaat tcatcctcac ggttttccaa taatttctct gcccagtcag gatcgacgat
    22261 catttgctgt ccaattgctg caagttctgc atatttcaat acctgctcta catcttcgcg
    22321 attgcggatc ccaccgacac caactaaagg gatctttcct tgaatcgtgt tatggaccac
    22381 ttcaagaatc gatttatcgt tgtatttatc agaacgagct attcgatcat acatatttaa
    22441 tgaaacatgc agataatcta gttttgactc acgtaatcgt tcaagaagcc agatcgtgtc
    22501 ttcaaaacgg atacctggtg tttcatattc ttctggtgag aaacgatacc ctacgatgaa
    22561 tggtttttta gcatattgtt caaccgctga gaaaaccgtt gttaataatt cttcaataaa
    22621 acgataacga ttttccaagc taccgcccca ttgatcctct cgtctattcg aatgcggaga
    22681 gaaaaattgt tggatcaaat acgtatttgc tccatgcaac tcgattccat caaatcctga
    22741 ttcaatcgct ctacgtgtgg ctttgccaaa tgcttggatt gtttcaacga tttcttcttc
    22801 actcattgct cgtggtgttt ccgcatcagg acgttttgct gcaactgcac ttgcagatac
    22861 aggctgttct ccagataaag ttgctcgact tgtcattcgt ccaccgtgga aaatctgaat
    22921 aatcgctttt gcgccttctc cttggattgc tttcgctagc tcacttaatc gaggaatcat
    22981 ttcatcatga gcgatgctga gttcacctgg ccagcctttt ccgatatctt ggacatttgc
    23041 agcaccagta ataacagcac caagaccttt agaacgttgt ttataataag tgatctcatc
    23101 ttcggtgatc actccattga aaaagctgag ttgtgtcgtc ataggcgaca gcatcaatcg
    23161 gttcttcaat tgaactcctg aaggtaaagt aattgattga tcaaattgtg acattgtcat
    23221 tcctcccata attcgctctg attaacctat cgagaatcat ctatcattaa accactcgat
    23281 tagttgtaca tgcaactaat ttgcttaaaa aattttattt tttttgtaac ttatctgttg
    23341 catcattcat tgtctgggct aattctttac ttgcttcatt tcccaaaact gctttgtatg
    23401 actgatgaag ttcttcccag ctaccatcga cttccttagc aaattggcgt ccttgttctg
    23461 taagataaac taatgacaag cgaccttcgc taactgtttt gacgtatcct ttatattcta
    23521 atttttcaac aaaacgagca atcgttgatg gggcggaata gagcatttgt gcaatatctt
    23581 tttgtggtat tccatctttt tcttttaata tcaataaaat aaaaccataa gttggtgcca
    23641 gacctgtcct tctaaacgct tcatcagcta atttattcaa catgcgatct agctttttca
    23701 cgctaaagaa aagacattca tctaacgctt tttcaattgg cttttccatt tcatcccctc
    23761 cattggcgta catatcatag tatgattttt attttttgtc aaaaaacacg gaataatgtc
    23821 cgcctcctct gtctagattt gaaaaaaaga agtagccatc ttcaaagaat ttcggcttgt
    23881 tttcgacaaa actccttctg gaacaccgtg aatcagaggt tgtgaaaaag tcgtttagtt
    23941 ttgagtatga agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt
    24001 aataccgaaa aactggcttt tgaacaccgt ttatatcaga ggttgtgaaa aagccgtcct
    24061 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atattttgtc gttttttgag
    24121 ctaatgccga tggtcagctg attgtacacc gtttattgag aggtcgtgag cctgccgttg
    24181 aactccgagt cacaaggagc aatttcaaaa aacagcttct catgttttat gactatggtg
    24241 acttgtgatc gaggagttgg caggagaata ctgtttattc gtaaagaagg ggctgtgaca
    24301 agacttttgt cacagtccct tatttccttt tattatagga tttcgccatt tgattggatg
    24361 acttgtctgt accaatcaaa tgattttttc tttaaccgtt tctttgtgcc attcccttcg
    24421 tcatcttgat caacatagat atatccataa cgttttgaca tttgtgaagt agaagcgctg
    24481 acgatatcaa tgcagcccca cgacgtataa ccaaataaat ctactccatc tttgatagct
    24541 tccttcatct gctcaatatg ctgcttcaaa tagtcaatgc ggtaatcgtc ttgaacggtt
    24601 ccatcttctt ctactttgtc tatagctccg agtccgtttt cagctatgaa cagtggtttt
    24661 tgatacctat catataattg attcaaagca attctcaaac ccttaggatc aatctgccag
    24721 ccccattcac ttgatggaag atacggattt ttaattcctc cagttattaa gtttccttgg
    24781 acccattccc aattttctgg atgagcactg actgcactag acatgtagta gctaaaagaa
    24841 acaaaatcaa cagggtaggc tgctaagatt tcttcatcac ctacttctat ttttaagttg
    24901 acaccttttt cttcaaacat tcgttgcgta tacgctggat aatatcctct tgcttgaaca
    24961 tcactaaaga acaaagaagt tctttgctgc tcaattgttt tttgaatatc atccggatca
    25021 caagaatacg gaacaagaag ctgatagctg atcatacaac cgacttgtga acctttgata
    25081 atttcatgac aagcttttgt agctaaagca cttgctataa actgatggtg tgcaccttgg
    25141 tatttcgctt gttccaaatg gggatggttt tcttcaatta ctcctacgct aacaaaaggg
    25201 tgatgtttta cacagttgat ctcattgaaa gtcatccaat attttacttt atttttatag
    25261 cgtttgaata ctgtttcagc gaaacgaacg taaaactgaa taagctttcg attaggccat
    25321 ccaccatatt ctgtaaccaa atataacggc atttcataat gggaaagaga aacgactggc
    25381 tcaatcccat attttagaca ttcgtcaaac acttgatcat aaaaaaataa tcccgcttca
    25441 ttgggtgttt cttcatcacc atgaggaaaa attcttgtcc atgcgataga catccgatag
    25501 catttaaaac ccatttcagc aaataaacgg atgtcttctt taaagtgatg atagaaatca
    25561 tttccgtgtc ttttaggata ataatacttg ctgttgggat cctgcgccgc ttttacttgc
    25621 tgatgcgtca tcatatgcca ttgatctgtc catttttctt taggtaaatc gctgtcgaat
    25681 gtatacacat cagacacaga taatcctttt tcatctacat cccatgcacc ttcacattga
    25741 ttggccgctg tcgctccgcc ccataaaaat ccttctggaa attttttcat atcgatcccc
    25801 ctaaacttgc tagttttctt gtttgattat ttttcttatg actagtaatg atatttttga
    25861 atctactact atttgtaaca ataaccattg tggtcggatc atatccctct ttgattaatt
    25921 cttgcaaatc tacttccatc aataaatcgc ctttacgtac tttttttcca tcagatactg
    25981 cactttgaaa gtatttgcca tttaaattca ctgtatcaat accgatatgg atcagtatct
    26041 ctgctccttc ttcactgact accccaattg catgtttcgt tggaaaaact gttgaaactt
    26101 ccccgtttac agaactgtag atttttccgt ccgttggaat gatcgcaaac ccttctccta
    26161 aagatccact agcaaatgtt ggatcgttta cttcagataa atcaattatt tcacctgctg
    26221 caggagtact taacactata tcctttgagg attcttcttc gatttcatcc ttgtagccga
    26281 aaagaaaagt tagcatacag gaactgatca tcgctaagaa ataactagca actagccaaa
    26341 caaatccttc accaatataa atcgggaaag acaaaatact tcttgtagca actgccaaag
    26401 caccggctcc tgcggcacca gctactccac caaatatagc tccacatata caagcaatgt
    26461 aaaatggtcg tttatattta agagtcacac cataaacagc aggttcagtg attccaaata
    26521 atgctgtgat aaatgcagat aaagataaac tttttacttt cttatttttc gttttcaaaa
    26581 ataccccaag tactgctcct gcttgcgcag ctacggcagt catacatgct ggacctagcg
    26641 tatcacgacc gtagaaagaa agattgttgg tcattactgg tacaagtccc caatgtaacc
    26701 caaaaatcac taacacttgc caaaatccgc cgataacagc accagataaa acagggctaa
    26761 agttataaac agctaaatat ccagctgcaa tcagctgact tgcataatct gcaattggac
    26821 ctacaactaa taaaataatt gggaccatca cgatgataca aatgaatggt gtcaataaat
    26881 ttcgaatact ttcgtgcaag cttttgcgaa tcttaggctc aatataagaa agaacccata
    26941 cagctaaaat tgctggaata accgtacttg tataccttgc tagaatcacg ggcatcccta
    27001 gaaatcgcaa ggttatgcta tcactatatg cactgacaat cgtaggataa acgagagctg
    27061 ctgcaataac catagcgatg aaacgatctg tattgaactt ttttgcagca gtatatgcca
    27121 aaaatatagg caagaaatag aaaaatgcat cagctgctgc attcaaaatg atataagttc
    27181 ctgattcagt agttaataaa ttcaaactcg tacataaggc gagtactcct ttgatcaaac
    27241 cacttcctgc caagacgcct aaagtcgggg caaaaacagc ggcgatcatg tctataaaag
    27301 agtttaaaat gccttttttc tcagttcctc tctttccact agatgcatca tcttctagtt
    27361 tcatttgttt ggataatacg tcatacactt catttactgc atttcctact acgacttgaa
    27421 acattcctcc agcttcgact acagtgatca caccttctag ttgctctacc ttctccttat
    27481 ctgccttctt attatctttt agggtaaagc gtaaccttgt tgcacaatgg taaacattgc
    27541 tgacattttc ttcgcctccg acaaatcgga caatatcttt cgctaattgt gaatagtcca
    27601 tttttacttc ccccttgtta attaatgccg tagcaatcct tcttacaaga taagtatagt
    27661 tcttagaaaa cggtttctcc attcaattag taccccttct aatagcgaac gaaactgtac
    27721 aatagtgtgt atggtttact tagccgagca aatcactcac tgcttgaaag aaaacaagta
    27781 tatcgtttct cttatagtca aaggagacaa aaaaaacacg cttgatcttc ctttgctgat
    27841 gtataagtgg tatctcaagc tgatactctg tgatttttgt ttctacttgg cttttgataa
    27901 gacagcacaa caaagtctcg gcatttaacg gaagcataac taggtcagaa ctaggagaga
    27961 ttagttgctg aatggaatct atctttttat ggatttttat ttgattttct tctttgtagt
    28021 aatgatcaag cagttttgtt ttcttttttt cttcaactat ggtcagcttt tcacgcaaaa
    28081 tctgataaat ctcccaagat tcaaactcat ctagaacact aggtagataa atcaaatcat
    28141 cccactcaaa aataagctct tgctcagtag tcaaaattgc atcatattcc gttattttgt
    28201 ttgattgatt tttgaaaaga tacactggtt ctatccggca ttctttgatc cacatgttca
    28261 tactttgttg aatctgtttt tttagtgtat tcaaaatact aattggctgg ttactaacaa
    28321 tcagtatctc cccttgtttt cgaaaaggat tcaacgcttc ggcaagatac aaaacaaaat
    28381 aagcgctttc agctaaattg ggacgtaatt gaaaatgtat tgggaagaaa cgccgaatta
    28441 aataaatttc taaaggataa cgggagatga tcttttgtac aaaatgattc atggtattat
    28501 gtccggcatc catcctcgtt ttcatttgtt tgatatgggt tagcaaaaat tctgtttcat
    28561 ggaacaataa cgaaacagga agatctaaaa aacgaataat cgtttgctca aatgctctta
    28621 gattcttctc tatttctttg tttttttcat cattaatcat caaataattt aactctaata
    28681 gtcgattttc aattgcttgt ttttcttgat tggaaaaaga atagggtagt tctgatgata
    28741 acttttttgt gagggtctct accatcggaa taaataatgt atacctgttt gttttttcta
    28801 aaagttcttc tcttcgaaga atggtcaaaa cgagataccg agaaaatcgt atgaagtcct
    28861 ctcctgaaac aatataatta tatgatataa gaacctcttt taatgtcttt tggacagtcg
    28921 gcatgatatt ggaaaaaatt gtactgattt gttgaggaaa ccttgcgtgt tggatcaccg
    28981 tttctgttcc aacaagagat aagaaaattc tttttgaatt ttcttcagca atgattttta
    29041 gtccttttgt cgacgaaact tccagttcta atttaggatt gcgctcgatc caacgcaaaa
    29101 tcgtttttat ttgtaatgat acggctgttt ttgaaagaaa gaaaatgtct gctatctttt
    29161 gcatactgac ataccctttt tgaaacaata agtacgtcac aatagttgaa gctcggaaat
    29221 ccatgctgga atagatttta tgtttcgtca cctcttgtat gatttgctgt ttagtttcag
    29281 attcaattga ttctaaaaaa taacctgaac gtttatttga ctggataatg attttcttct
    29341 cgtagatagc aagcatattt ttgatttcag tttggatcgt tttcttgttg gtacctaaag
    29401 cttcagctaa ttcttcgctt gttatccaat gattcttatt tcttaatact acaagaattt
    29461 ggagttgtcg tttatttaag tccatttgct tacacctcct ctttgttata aacatacagg
    29521 aaaaacctct caaatgacaa tagtcacttg cagaggttta aaaatcattt gaagaaagat
    29581 ctatattcaa ggtttttacc attagactgg ataatttgtt tataatattc aaaactatct
    29641 tttttcaatc tcctaaagct tccgctccca tcattttgtc tatccacata aataaagcca
    29701 tatcgcttcc tcatttcccc tgttcctgcc gatacgatat cgattggtcc ccaccataag
    29761 taaccaatga tttggcaacc atcttttatt gcctcagcaa tttcctgaag atgtattttt
    29821 agatactcac aacgttttgg atcgtggatt cgattcaatt catctggtgc ttcatctagt
    29881 ccaatgccat tttcaactat gaataatggt aattcataac ggtctgtcaa ttcattcatg
    29941 acataacgaa accctagagg atcaattggc caactccaag gttcgggaga tttttccttc
    30001 aaaaagggat tatcgaaacc atttgctccg ccagtatcta cgcgcatttc tgcttctttt
    30061 ttatagacag cgctacgata ataactaaat gcaatataat ctgccgtgtt agcttgcaag
    30121 cactgttcgt ctccatctaa cattactggt gcacagtctt cttccttcca tgtcctgtaa
    30181 atataagctg gataatgccc tcggcacatg acatcggaga aaaaccatga attgcgttta
    30241 aattgcagtg aaccaaatac attctctgga tcacagtcat atgcataagt cgctaatgca
    30301 gaaaagctac acataatacc catcttagca tttggatcga ttttctttaa taattgagta
    30361 gcacgggcgt tcgctagaaa catatgatga caggcttgat aaatcacttt ttttgttagt
    30421 gtagcaatgg gttcaagttt atctctagca gggaatgtaa ccaatccagc agctgcataa
    30481 ggcatacgaa aagcattatt gatctcatta aaggtcatcc aatatttcac tttcccttgg
    30541 tagcgttcaa agacggtctg cgcataaaat tcaaaaaagt cgattaattt tcgattttgc
    30601 caccccccat actctcctac caatgctaag ggggtttcat aatgactaag agtaattact
    30661 ggctcgatat catatcgatt taatgtattg attagtctgt cataaaatac gagaccagcc
    30721 tcatttggct tctgttcgtc tcctcttgga aatattcgtg cccatgagat gcttgttcga
    30781 aaagctttta aacctaactc cttcagtaaa cgaatatcct cttcaaatcg atgataaaaa
    30841 tcaatcgctt catgagaaag ataatggagt gattcgtcta aagcaatctc ccaaatcttt
    30901 ttttcttcat tccactgaat actaggatgc tggttcatga tcccgataag cgtatctgtc
    30961 acattaggta atttgccgtc ttccaaccat gcaccttcac attgattagc agctactgct
    31021 ccgccccata aaaaattttc tggaaatatt tcctgatcca taactatctc tcctcgctat
    31081 caacaatttc ttacttgaag tatagctcga ttcatcaaaa caagatattc taactatttc
    31141 ggcagaagag aagaaaaaaa ttgaatgcta ctcttcattt ttaatattta tatataacaa
    31201 atacataaga cgatccccga aagaaaacac tcgttaacca tctaagcaaa cgatttattt
    31261 tacttccaac acaaatgctt cataaggtcg taaatcaact ttgccgtctg gtaactgttt
    31321 cagaggataa tttgacacaa taacccttaa agcttcacgt ggaatagtga acgtctgctt
    31381 ttcactggac atattacaaa taacgagcca ttgctggtct tcatatatgc gagaataggc
    31441 aaagacatgc tcaggcgtct tttccactaa ttcatagtct ccccagacga tgatgtcatg
    31501 ttttctacgc aaatcgatca atttcttgta catataaaaa acagaatctt gatctgctaa
    31561 cgcttcttct gcattgattt ctttataatt tggattgact cgaagccatg gaattccagt
    31621 agtaaaccca gcatgttcac gggcgttcca ttgcataggc gtcctagcat tgtctcttcc
    31681 tttcgccttg attgattcca agatttcctc ttttgtaaat ccagaagaaa tcctttcgtt
    31741 atacatattg attgtctcaa tatcttttgc ttccgcgata tcatcgattg ggcaattcgt
    31801 catgcctaac tcttctcctt gatagatata aggggtgcct ttcatcatat ggagcaagat
    31861 agcaaacatc ttggcacttt cttttcgata cacatcgtca tttccccaac gagaaacaat
    31921 tcgcggaaga tcgtgattat tccaaaataa actattccat ccttcatcac ctaaagatgt
    31981 ttgccatttg gataatactt ttttcagttc agagatactc aagggtttca aatcccattt
    32041 gtctttgcct tcttgctgat ctaatcctat gtgttcgaat tggaagacca tggataattc
    32101 atttctttta ggattggaat aaagtttagc gatttcggta gttgctcccc atgtttcgcc
    32161 aacagtcatc agatttttgt caccaaaagt tgcttgattc atttcctgaa gatactcatg
    32221 cagtttaggt ccattacttg tgatttcttt atccggttct ttgccaatca tatcgatcac
    32281 gtccatacga aagcccccaa tacctttatc gatccagaaa ttcatcattt gataaatctc
    32341 ttggcgaacc tgtttatttt tccaattcaa atcaggttga cgcttgctat acaagtgcag
    32401 aaaatattgc cccgtttttt catccaactg ccaagcagaa ccactgaata ttgagcgcaa
    32461 tctattaggc tcttttccat tgaccggatc acgccaaata taatagtccc gataaggatt
    32521 ttctttattt ttacgggcct caatgaacca cggatgttca tcagaagtat gattcaccac
    32581 cagatccatg atgatacgga tatttctttt ctttgcttct tcaatcagtt cttccatttc
    32641 ttccatcgta ccgaattctg ccatgattgc ttgataatta ctgatatcat acccattgtc
    32701 atcattcgga gactcgtata ctggagaaag ccaaattgca tcaataccta aatacgccag
    32761 ataatccaac ctggaaataa tcccccgcaa atctccaata ccatcttgat ttgaatcttg
    32821 aaaacttctt ggatagattt gataaacaac tgaatggtgc caccattttt gttccatgat
    32881 tttcctccta taaatggatg tttctatttt ttgcttaatc atttatttta gtctctctca
    32941 ctaaaaattg taacgctttc aaatagctat tgcaccttgt tatcggtaac agaataaaac
    33001 aaaaaaacag ctgaggaaat tccctcaact gttttttgaa aggattgatt tatgcaggga
    33061 agaatgctga tttcacaact tctttataaa cggtgttcac tcagctgtcc cttggtatta
    33121 gctcaaaaaa cggcaaaata taagaaacta ttttttcgtt tttttctcta atactcaggc
    33181 cagaacgctg atttcacaac ctctttattt cacattcaat atccacatga atcccacaaa
    33241 tacaaagaac agaccataca tgattggaga tacttctttt cctcttttag ctgctaacat
    33301 ggtaattgga tagaagataa aacctaatgc aatcccatct gaaatactat aagtcaaagg
    33361 catgccgatc aagatcaaga atgaagggat cgcaatctct aagtttcccc attcgatttg
    33421 tcgcaaagat tgtgccatca atactcctac cataatcaat gctggtgcag ttacttgtga
    33481 agtaacaact gatagtaatg gagaaaagaa caagcctaac aagaagaaaa tccctgtagt
    33541 aatagctgtg atacctgaac gtcctccaac ggcgatacca gctgatgatt ctacaaatgc
    33601 accaacagga gaagtaccaa ataaggaacc cgcaagcata gctgttgaat cagaagctaa
    33661 agctttccct acacgaggca tcttgttgtc tttcatgaaa cctgcttggt ttgctaatcc
    33721 aactaaagtt cctgctgtat caaagaaagt cacaagcaag aatgtcagca ctacgaccca
    33781 catttgaaga gaattgatgt cccctacatg ttttaatgca actaaaaatg ttggtttcaa
    33841 acttggtgct gcggcaacaa tttcagaagg cattggaatc aaacctgtga ccagacctaa
    33901 aatcgttgta gctgccatcc cgatgaagat gccacctggt acacgccgaa caagcaagat
    33961 agcagttacg actaatccaa aaatcgtcaa ccaagtagaa ccaacgttga gtgatcctaa
    34021 tcctactaat gtagattcat tcgaaacgat gatcccacct tcgctcagac caaggaaagc
    34081 gataaataga ccgataccgc cagaaatcgc atatttcaaa tctgctggga tcgcatcaat
    34141 gatcatttcc cgcagcttga agattgtgat caaaataaaa atcaaagaag caacgaatac
    34201 gccggctaat gctgtttccc atggaatccc cattcctaaa caaacagaat aagcaaaaaa
    34261 agcattgatc ccaagagcag gtgccgttcc aattggataa cgggctaata cccccattaa
    34321 aacacagccg atcgcactgg ctaatgcagt cgcagtaaac actgctcctt catccattcc
    34381 agaagcacct aatacagttg gatttacaaa taagatataa gccattgaga taaatgttgt
    34441 aaatcctgcc agtacctcac gttttaccgt ggtgttcaat ttttctattt cgaagtagga
    34501 aagtattttt tccttcatct tccatccccc taaatccgaa cattataaat aaagtccgtt
    34561 aaaatttcga tttattaata aaacaacgtg ttttatcata tactaaaaca aaacataagt
    34621 aaacaaaaaa ttcggatttt aagcaaaatc cgaacgttcc atctgattaa atccctttat
    34681 ctcaaagttc atgaacattc actttggatt acaagaattt ctttattgtg ttaataaagt
    34741 ttcttcattc tagtctcaaa aatcaatagt gtgatttgat tttaccattt cgtttctgtt
    34801 cttctttgat gaattctttt gtatcgacag gattcagatt atttagtccg ccaaaacctg
    34861 tatcgaccat ttttccccag ccttttgtct tcttttttcc tgatttgaga ttctttgctc
    34921 gaagcttctc actatgtttt gctcgccgat acttcaaata accttctaat cttcccatta
    34981 gatccactgt ttttcctcct ttttattcaa tcagacgact cagcttttcc tataacaaaa
    35041 taattgcctt cagggtcaga aaaattgaaa gtcaagatgc cattgttatc tgtgatttct
    35101 cctggttctt ccatgttctc gtagatagtt tcaaattcat ccgtaaaaaa tactaaagaa
    35161 ggcggtggtc ctaatacctc tggtgaaaac ttctgcacaa atacttttgg gaatacgcct
    35221 aattctaatt cttttgagat gctgagtaca atactcttaa attcttctgg caattcgatt
    35281 gtttcagaaa tttctgcacc aattttttct acaaagaatc ggcaaatcat ctctacgtca
    35341 ttgacataaa gcatcacacg tgttttttgt atcatcattt gacccttctt tctatttgat
    35401 tttctttcct gtctataaac tgattccatt atatcacgaa agcgcaaaca ccttgtgttt
    35461 gatactattc aagaaaaata aagcaatagt ttctaggatt gctttcctcc acaaactttt
    35521 tttacaaaaa aaaaacggca atgaatgccg ctcttcttat ttcgattctt ttataattct
    35581 gcttctgatt catctttggt tagtgtgtgt ctaacactag ttacgccaaa tgtttgatcg
    35641 attttttcct tcaacgcttc gattgcctgt gcgccacgtg ccgcttgttc agcattgatg
    35701 gattcaatga ccagcaccgc tgcttgtgtt tcttccgtca gcatcgttct ttgggcttca
    35761 cgccagttga gacagcgaca gatcgctcct tgttcatcat agtagatgat ttcttccgga
    35821 agtgccggag catcggaatc tgcacctaaa ggcaggaatg attcgccacc ttgggctttt
    35881 cctaaatgca gatttcctgc gatcttttcg atatcttctc cgccgcaagg tacgccaaaa
    35941 gacaaggaaa tactattata gatatctaca agcggattga ttgggaaaaa ttcccgttct
    36001 tgatttgcac gtttcagtaa agcttcaata gaagaacgtg cacctttttt agtcttgaat
    36061 gtggtaaatg cctgacgcca ctgagcaatg acttcgtttt ggctgaatgt ttcttctgta
    36121 aggtaatttc ttgcttcttt tgctgcctca ttcaataatt gatgatacgt ttcttcactt
    36181 tcttttgtta cgtggttatc gataccattt acggataaga tttcgatggt tgcttcagga
    36241 aatacttccc agaaattggt atccactatt acttttttca tctgttcaca cctcttgatt
    36301 agaataattg cttgatgaat agatagtctg tttggggatc atctcccata taaaaaacat
    36361 gttcgctgta tttgataaat ccttttttac gataaaaagc gagcgcaaca tcgttgtgtt
    36421 cccaaacacc gagccaaatg gctgtttttt gcttttcttt tgctttttca atagctgtat
    36481 ctagtaaaaa tgtaccgata ccttgatgtt taaatttttt tcgtacatag attcgctcga
    36541 tttctaaaaa atgatcagcc atttcctcag attgactcgt tcctgtattt agtttcaggt
    36601 aacccgcagg ctcttgatcg atactcacta ggaaaaaatc ggtttcttta tcttttagct
    36661 cttctgtaag tttttctagt gcataagctt gtgtcaagta atcagctaaa tgctccggtg
    36721 aattatcttt tccaaatgta tctgtaaatg tttcgatact aatttgttgt agtaagtcta
    36781 catctgaagg cgtcattttt cgaatttcgt atttattcac ggcttcttcc tttcaataga
    36841 tccttttatt gccttttttg acaaaattcc aatcttcgct aacattcttg catactttat
    36901 ttaaaagata ttccaattgt tttgcttctt cgtcagaaag accatttaat gcgactgcat
    36961 tggagtagtt gttttctcga atgatgaaag gatagatttc tgctcctttt ttagtcggat
    37021 agagtttctt gattttttta ttttctttat cttccaaacg ttcgatcatc ccattggatt
    37081 ctaatttctt gattgctcgg gcagtcgttg tacgatctac tttgatcatt tctgctagtt
    37141 tttcttggat gattccagga ttttcgcaaa tacgtactaa ataaagatac tgtcctcttg
    37201 ttaaatcgac ttctttgaat tcgatattgc taatagaatc tagcgctcgg gcaatcattc
    37261 cgatgtctcg aaggatttca gccatttcat cccaccttta ttttgtttgt aagactagtt
    37321 cacctctttt tgttgcaaat gcaactattt tcaataaaaa aatcaagttc ttttttaata
    37381 actagtaaag tatattcttt tcttctttta cgaaaaagct caatcacaat agatctggtt
    37441 tttgttttct aaaataagta actgtttctt cgttgttcgc ttttctgata gctttggcaa
    37501 ctcttctata ctaaaaaatc ccatgttgga agtttcatta ttctcaataa acttggcctc
    37561 ttcaccgtgg atcgcacaag caaaaacaag tttataatac tgaaaaagct gtggaatatc
    37621 tttttgttta ttcgtatcaa aaactgctcg caactgagta gtttctactg ttaatcctgt
    37681 ttcttcatag acttctttac gcacattttc ttcaggagac aatcctattt cagcaaatcc
    37741 accaggaagt gaccattctt tcgtccgttt atcttcgatt agtaggacct tgccatcttt
    37801 tttgatatag gcacgaacat ctacttttgg tgttggatgt ccttctccaa tcgttgtgag
    37861 cgcttttatt tcttcgaaag tttcttttcc tatttcactg atcagttcca atgaaatcgt
    37921 ccggatctcc tcaaaacgct ctttatcaaa tacatctttt ccataatata gaccagcttg
    37981 agaaagtgcg agtagtcttt tgtattgagc caacttcttg ttcattctct tcccttcttt
    38041 tttagcaaat gtatgactat gtaatcaagt atagaagact ggtttaatta cggcaaataa
    38101 atataatgaa atctgcaata aataaaagaa tgttaaaaaa ctcgagaaca aaagacattc
    38161 gacttctctg gggctgtgaa taaatggcgt tcaaaagctt gcatctgcgg taataagccc
    38221 caccaaacga aaaatatgac gagctattct tgtctggctg ttcttattaa ttgaggcagg
    38281 acagcttttt cacaacctcc ccactaaacg gtgttctcct accaactcct cggtcacaag
    38341 tcacaatatt catcaaacat gagaagctgt ttttttgaaa ttgctccttg tgactcggag
    38401 ctgaacgaca ggctcacgac ctctcggtaa acagcgttca aaagccaatt tttcgatatt
    38461 aagccatttc tttgttactt attgtcattg atttcttttt ctaatttatc caatagtgga
    38521 gtgtaatcca cttgagtata gtctgttaca tcaaattcat atagtgttcc taactggaat
    38581 ttgtcatatt ttcggtcggc gatgatcttt ttgaatgctt ctttcgtaat atgattggtc
    38641 cctttcgttc gatcttccaa tacgtcacca tagtgataat gatccatgat atagctcaaa
    38701 tgacgatctg attcacgatc acgtttgtac cgacgttgcc ataacacttc aaagtctgct
    38761 gttaggcgaa tcgtgatcac ctgatatccg tatctatctg ctaattcttg gagtcgtgct
    38821 ttttgcttat cactaaaagg atactcggac acaatcactt tctttcctgc ttccatatac
    38881 aaatcaagtg ctttgtaata gaaaggataa actttcgtcc tttcttgttc cgcccgttct
    38941 tccaaattgt taaacccgat ggattctgca tagtattcct tgatttcatc gagcgtgatg
    39001 gcatacatat ctggaaatcg ttcccgtagt ttattcataa gatatgtttt tcctgtacca
    39061 ggactaccag ccagaagaat gaaatacttt ttcatctcat ttatttccta agttaattgg
    39121 actttccaag ttcataaaca gtccaatctt atgcttgaca atttctttta ctgcttcatt
    39181 tgctggaatc acattatggc gaagagactt gttgatttct gtttcactaa aggtttcttt
    39241 agctactttc gtccagttga ctaaaagctc cgttccaaca ttgaatttgc ggatcccgtt
    39301 attgatcaat tcaggataat cttcttcttt cacacctgtt cctccatgga taactagggg
    39361 gacatcaact actgcatcga tttctttcag caagggaatg tttacttctg tttttgattt
    39421 gaattgtcca tgattcgtac cgatagcaat agctaatgca tccacgcctg tagcttctac
    39481 aaatttcact gcgtcttccg gtcttgtata taccttgtca ttttcagcga catggattcc
    39541 ttcttctgta ccgccgattg ttccaagttc tccttctacg gaaacaccgt gcgcatgggc
    39601 atattctact actgcttttg tcttcaggat attttctttg aaaggcagat gggacccatc
    39661 atacatgaca gaagtatatc cgctgtcgat tgcttctttg atatcatcaa agtctcgggc
    39721 gtggtctaag tgcaagactg catcaaccat ttcttcttct gcaatagctg tcattacatt
    39781 gactaacaca tgcatgccga tatatttagc ggtatcgaca cttgtttgaa taatgatcgg
    39841 cgaacccatt tcttttgctg cgcctagcat agcaggaagc atttctaggt tatgcgtatt
    39901 aaaagctcca actgtaaaat tcaactcttc tgctgttttt gttacttctt tcaatgttgt
    39961 atacatcttt tattgccacc ttatcttttt atttgtttcc tttgatcgtt acttgttttg
    40021 caatttgtcg catctcatcc attttgccca tgtagtaatc gatcccttga tcatcaccag
    40081 cacgagcagc atctgcacgc ttctggttat agaggctcat cagtttttta tacccatctc
    40141 cgatcgtctg tttattttcc aaactctttt ctaaatattg gatggcttga tcgttcacat
    40201 acaattcaga aaatttaagt ccaacttgtt cataaagttt cgctaattta tgcttatctt
    40261 gggtagtgga aatctcttgt ttcaattgtg taatctctga ttgaatcttt tcggtcgctt
    40321 ctggcgatag ggctttttct tcttttgcca gaactttttt cggttctttt tcttttttct
    40381 taaaaaatcc aaacatcatt ttccctactt tcaattaaaa tgctttcaaa actgggctta
    40441 agatccaggc atataagagt gctgcggcta ctgtatctac atcggttgct gtagcattgt
    40501 tgaatcccat cgaattaaag atcgttacta gcaaagcggg caataatgta ataaagaaac
    40561 catgagcaat accgccaatg atcgctcctc ggcgtccgcc aactgcgttg ccaaatatcc
    40621 ctgctgtccc tccggcaaag aaattggtta gcataccagg taaaatcatc gctaagccga
    40681 acatgggcaa agtaaacatg gcaataatcg taccaatcgt tgtcgtaatg aaacctaaaa
    40741 tgacagcatt tgggctataa ggaaagaaaa ctggacaatc taaggcaggg atcgcatcag
    40801 gaactaattt catagctatc cctcgaaatg ccggcacgat ttcacctaac agtagacgta
    40861 caccagctag caatacatac acacccacta cgaattggat ggcttgtaaa aaggcaaaca
    40921 tgatatagtt ttgatctcct gataattcag aagcgaatgg ttcgcctgca aataaaacag
    40981 tgatgatata tagcgggacc atcacgacca tgacagacaa ataagtatct tgcagaaatt
    41041 cgaaatgtgt cggcaacttg atatcttcga tcgacttttt attttcgcct ttctcaccaa
    41101 aaagcttagc aacaccggct tcaaataagt acccgatcgt acaaaaatga cctaaagcaa
    41161 tatcatttga tccagtgatt ttacgaatga tcggttgcgc tactgccggc atagcaatgg
    41221 cgaaacaagc tccgataaaa ccaccgacca agatcaatac gatccctcgc agaccggcaa
    41281 aatagccaaa gactgtcgtc atcgttgcca tccataaaat tgcttgacca gttaaaaaaa
    41341 tgtacttcca ttttgtgaaa cgagccaaaa taatattgaa tacaaaaatg gctaagaacg
    41401 tcagtgcaat atctctacct aaacccaaat cattcattgc ttgaccattg atagattcaa
    41461 tagaagggat gatcccttgc atatgaaatc cttcagtaaa gattttcccg aaataagtta
    41521 aacttccaac gatgatgctc gaaccggcac tcaacacttg aaatcctagg agtgtcttta
    41581 acgtgccaga gatgacttgt cctgctgatt tcttctgcag tagtagaccc aacatagcaa
    41641 tcaatgcaat ggtgatcgat gcctgagtca aaatattttc gatgataaaa ttgataacgc
    41701 ccat
//
LOCUS       DADVXE010000017        40437 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.017, whole genome shotgun sequence.
ACCESSION   DADVXE010000017 DADVXE010000000
VERSION     DADVXE010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 40437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.017"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(222..2219)
                     /gene="tkt"
                     /locus_tag="KB913_001021"
     CDS             complement(222..2219)
                     /gene="tkt"
                     /locus_tag="KB913_001021"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBB6819401.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2321..2572)
                     /locus_tag="KB913_001022"
     CDS             complement(2321..2572)
                     /locus_tag="KB913_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBB6819402.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2719..3342
                     /gene="lexA"
                     /locus_tag="KB913_001023"
     CDS             2719..3342
                     /gene="lexA"
                     /locus_tag="KB913_001023"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBB6819403.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3522..3740
                     /locus_tag="KB913_001024"
     CDS             3522..3740
                     /locus_tag="KB913_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819404.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4029..4541)
                     /locus_tag="KB913_001025"
     CDS             complement(4029..4541)
                     /locus_tag="KB913_001025"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBB6819405.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4555..6852)
                     /gene="recJ"
                     /locus_tag="KB913_001026"
     CDS             complement(4555..6852)
                     /gene="recJ"
                     /locus_tag="KB913_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBB6819406.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6994..7437)
                     /locus_tag="KB913_001027"
     CDS             complement(6994..7437)
                     /locus_tag="KB913_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBB6819407.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7438..8226)
                     /locus_tag="KB913_001028"
     CDS             complement(7438..8226)
                     /locus_tag="KB913_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6819408.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8223..9164)
                     /locus_tag="KB913_001029"
     CDS             complement(8223..9164)
                     /locus_tag="KB913_001029"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBB6819409.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9341..9928)
                     /locus_tag="KB913_001030"
     CDS             complement(9341..9928)
                     /locus_tag="KB913_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBB6819410.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10149..11456)
                     /gene="obgE"
                     /locus_tag="KB913_001031"
     CDS             complement(10149..11456)
                     /gene="obgE"
                     /locus_tag="KB913_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBB6819411.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11750..12760
                     /gene="gap"
                     /locus_tag="KB913_001032"
     CDS             11750..12760
                     /gene="gap"
                     /locus_tag="KB913_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBB6819412.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12845..13780)
                     /locus_tag="KB913_001033"
     CDS             complement(12845..13780)
                     /locus_tag="KB913_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6819413.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13966..14925
                     /locus_tag="KB913_001034"
     CDS             13966..14925
                     /locus_tag="KB913_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HBB6819414.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(15011..16105)
                     /locus_tag="KB913_001035"
     CDS             complement(15011..16105)
                     /locus_tag="KB913_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6819415.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16294..17055
                     /locus_tag="KB913_001036"
     CDS             16294..17055
                     /locus_tag="KB913_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6819416.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17170..17610)
                     /gene="fabZ"
                     /locus_tag="KB913_001037"
     CDS             complement(17170..17610)
                     /gene="fabZ"
                     /locus_tag="KB913_001037"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBB6819417.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            17830..18585
                     /gene="fabI"
                     /locus_tag="KB913_001038"
     CDS             17830..18585
                     /gene="fabI"
                     /locus_tag="KB913_001038"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBB6819418.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(18695..19708)
                     /locus_tag="KB913_001039"
     CDS             complement(18695..19708)
                     /locus_tag="KB913_001039"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBB6819419.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            19873..20793
                     /locus_tag="KB913_001040"
     CDS             19873..20793
                     /locus_tag="KB913_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBB6819420.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            complement(21073..21573)
                     /locus_tag="KB913_001041"
     CDS             complement(21073..21573)
                     /locus_tag="KB913_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6819421.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(21680..22198)
                     /locus_tag="KB913_001042"
     CDS             complement(21680..22198)
                     /locus_tag="KB913_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6819422.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            complement(22199..23554)
                     /gene="rph"
                     /locus_tag="KB913_001043"
     CDS             complement(22199..23554)
                     /gene="rph"
                     /locus_tag="KB913_001043"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBB6819423.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            complement(23557..24378)
                     /gene="racE"
                     /locus_tag="KB913_001044"
     CDS             complement(23557..24378)
                     /gene="racE"
                     /locus_tag="KB913_001044"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBB6819424.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            complement(24540..25196)
                     /locus_tag="KB913_001045"
     CDS             complement(24540..25196)
                     /locus_tag="KB913_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6819425.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            complement(25212..25859)
                     /locus_tag="KB913_001046"
     CDS             complement(25212..25859)
                     /locus_tag="KB913_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6819426.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            complement(25872..26687)
                     /locus_tag="KB913_001047"
     CDS             complement(25872..26687)
                     /locus_tag="KB913_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBB6819427.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            complement(26701..27438)
                     /locus_tag="KB913_001048"
     CDS             complement(26701..27438)
                     /locus_tag="KB913_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6819428.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            27692..28702
                     /gene="trpS"
                     /locus_tag="KB913_001049"
     CDS             27692..28702
                     /gene="trpS"
                     /locus_tag="KB913_001049"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBB6819429.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            complement(28872..31292)
                     /locus_tag="KB913_001050"
     CDS             complement(28872..31292)
                     /locus_tag="KB913_001050"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBB6819430.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(31297..32340)
                     /gene="pheS"
                     /locus_tag="KB913_001051"
     CDS             complement(31297..32340)
                     /gene="pheS"
                     /locus_tag="KB913_001051"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBB6819431.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            complement(32649..32990)
                     /locus_tag="KB913_001052"
     CDS             complement(32649..32990)
                     /locus_tag="KB913_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6819432.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            complement(33059..36781)
                     /gene="addA"
                     /locus_tag="KB913_001053"
     CDS             complement(33059..36781)
                     /gene="addA"
                     /locus_tag="KB913_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBB6819433.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            complement(36778..40305)
                     /locus_tag="KB913_001054"
     CDS             complement(36778..40305)
                     /locus_tag="KB913_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBB6819434.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
BASE COUNT        11460 a         8676 c         7056 g        13245 t
ORIGIN      
        1 aagttttttt gagttacgta aatggaaagt tttgtctcgc ttaatttgac aaataatatt
       61 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
      121 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      181 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      241 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      301 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      361 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      421 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      481 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      541 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      601 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      661 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      721 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      781 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      841 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      901 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      961 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
     1021 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1081 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1141 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1201 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1261 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1321 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1381 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1441 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1501 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1561 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1621 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1681 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1741 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1801 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1861 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1921 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1981 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     2041 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2101 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2161 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2221 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2281 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2341 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2401 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2461 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2521 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2581 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2641 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2701 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2761 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2821 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2881 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2941 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     3001 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3061 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3121 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3181 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3241 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3301 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3361 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3421 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3481 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3541 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3601 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3661 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3721 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3781 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3841 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3901 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3961 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     4021 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4081 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4141 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4201 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4261 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4321 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4381 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4441 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4501 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4561 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4621 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4681 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4741 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4801 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4861 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4921 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4981 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     5041 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5101 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5161 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5221 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5281 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5341 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5401 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5461 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5521 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5581 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5641 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5701 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5761 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5821 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5881 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5941 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     6001 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6061 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6121 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6181 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6241 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6301 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6361 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6421 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6481 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6541 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6601 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6661 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6721 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6781 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6841 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6901 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6961 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     7021 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7081 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7141 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7201 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7261 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7321 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7381 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7441 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7501 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7561 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7621 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7681 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7741 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7801 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7861 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7921 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7981 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     8041 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8101 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8161 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8221 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8281 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8341 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8401 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8461 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8521 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8581 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8641 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8701 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8761 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8821 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8881 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8941 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     9001 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9061 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9121 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9181 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9241 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9301 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9361 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9421 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9481 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9541 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9601 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9661 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9721 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9781 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9841 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9901 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9961 tattttacct ttaattgaaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
    10021 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10081 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10141 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10201 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10261 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10321 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10381 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10441 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10501 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10561 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10621 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10681 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10741 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10801 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10861 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10921 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10981 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    11041 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11101 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11161 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11221 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11281 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11341 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11401 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11461 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11521 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11581 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11641 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11701 attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata tgacagtaaa
    11761 agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca tcaaagaagt
    11821 ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta tgttagcaca
    11881 attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg caacagaaga
    11941 ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg caagcaaaat
    12001 cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt tttatacatc
    12061 tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta tttctgcccc
    12121 agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag atgaaaacga
    12181 caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg cttatttctt
    12241 aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct acacttccac
    12301 acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc gttcagctgc
    12361 tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag ttatccctga
    12421 gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg gttcattaac
    12481 tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg aagcaatcaa
    12541 aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg tttctagcga
    12601 tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag taacaactgc
    12661 tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg gatttacttg
    12721 ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat caatcgataa
    12781 aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct acttttaaac
    12841 tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat ttttcaggat
    12901 ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct tttggtccct
    12961 tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct tcgtctccat
    13021 gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt gcttcaccga
    13081 aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc ggaaatgctg
    13141 gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa gaataaccgc
    13201 aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc atcataactg
    13261 ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca ttgttttcta
    13321 gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat ccaatgtaat
    13381 ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa cccatatcat
    13441 gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca tgagccacaa
    13501 gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat ttcagaccgt
    13561 cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat ttatgtgcat
    13621 ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag tctttctcag
    13681 aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca acaatcagag
    13741 ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca tctcatttct
    13801 cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc aatgttcatt
    13861 tttataaccc gcgaattgta aaattaagtt agaaaaataa aaaggcattt atggtacact
    13921 caaattgtat ttccgacgaa agaaaacaaa ggagtgtaac cataaatgac ctacaaacat
    13981 cttaccatag acgaactgac aatgatagaa tcatattatc ttcaacataa taagccggtt
    14041 gaaatcgcta accgaatggg acgtgctata caaactattt ataatgtagt caataagttc
    14101 aagcaaggca agactgctct tgattattgg caccagtata aagaaaataa gaaaaaatgt
    14161 ggtagaaaag tcattcaatt acctgctcat gaagtagatt acattaaaga gaaagtcact
    14221 cttggttgga cgcctgacgt cattatcggg cgaaaagaaa ggtctgtttc atgcggtatg
    14281 agaacacttt atcgtttatt ttctaaagga atatttgata ttgacacact accgatgaaa
    14341 ggtaaaagaa aacccaatgg ccatcaggaa aaacggggaa aacaacagta tcagcgctca
    14401 atccatgatc gacctgataa ttatcctgat ttcaattctg agtttggtca ccttgaaggt
    14461 gatacgatcg ttggcattca tcataaaagt gccgtcatta ctttagttga aagattatct
    14521 aaagtcatta tcacgattaa acccaacggc cgtaaggcat tagatattga aactgccctt
    14581 aatcaatggt tttctcgctt ccctaaaaac ttctttaaat ctattacgtt tgactgtgga
    14641 aaagaatttt ctaactggaa agccattagt aaccaacatg atattgatat atattttgcg
    14701 gaccctggaa caccttctca acgcccatta aacgagaatt ctaacgggat tctgcgtcgt
    14761 aatggactgc cgaaatcaat ggattttaga aaagtgaatc agacatttat ttccagtgtc
    14821 agcaatcaac gtaatcatat tccaagaaaa tcattgaatt acagaacacc aatcgaaata
    14881 tttttgagct atgtacaaga agcattttat tctagcttaa tttgacaaat cataacctat
    14941 aaaaaaacaa aataaaaaag cagaaataac tggctatttc tagcggatta tttctgcaat
    15001 aactaattat ctatttttta ttttcaatta atttaaagct tgaccatggt ttcaaaaagt
    15061 caaggaggaa taattcgtca tcggagattc ttcctacaac attgacacgt ccgtcgtttt
    15121 tcatatcctt caaggcgatt tgtgtttctc ctttgtattg accgtaccct tcattgtcaa
    15181 tcagtacatc cccatgatgc atatctcgcg tattatgagg cgggaaatct ttatctttgt
    15241 agtatacacg agtcatcgtt gaacgaagga tatattctga gcgatcccct cgataactat
    15301 gaaggttatc aaacaagcag attcgttcgt tttctgtaat accttcttcc gtatctactt
    15361 tcaatgttgg ataatccgcg ttaaatgctt ctgccatttc tttcaattct tcttcacttg
    15421 cgtacgcatt tccaatagaa atatcatcaa tcaatcctgt aaggattaaa tgcttcactt
    15481 gtgtcgcaat ttcaagatct cggtggtctt ccagcgtgca caagccatct tgcgtaggcc
    15541 aagggccaaa ctcagcagat tgcgaattga cgaatgccat cgtattcaaa ttatattttc
    15601 tgaatttttc tgaacaaaaa acaaagtgtt cgtatcctaa accagagtat cgatgaggat
    15661 aaaaattatg agaacctaat aaattatccg tgtttggcga ataactcatg atgttgtcaa
    15721 cgtaattcgt gcccgaactc atattgatct cgattttgat accaaaagga ttgcgcgtca
    15781 tttttgcttc ttctgctcct gtgaatccga tatctaagcg gaccccgtag gcacccatct
    15841 tatggaaaaa agataagtca tcgtaagaaa tctccaactg ttcaaataac gctggattga
    15901 tatcaaccat tacttccatg cctaggctat tcgcgtaatc aactacttct ttaaattctg
    15961 aaagaacttt ttctttatca tcattgatct gcagcaaact ggtaaaaacc cgtttatacc
    16021 catacttatg agctaaatcc aagtacgctt tgtccttttc aaatgttgac cgttctggat
    16081 aaatcgagat tcctaatttt cccatattac catttcctcc tgcatctttt cgtttttgta
    16141 tccacttaca ttatagcaaa cacaaagtaa atggtctaca ccttttcttt ttcttttaaa
    16201 ataaatgata aattccaata atttaagtag gtattttccc tctattttgt tatcattaaa
    16261 gataacaaaa tagtaaattg gaaaggaaca gttatgaaga aaaataaagt tattttaagt
    16321 attagtttag cagcagcatt gctgtttgct gctggttgtt ctgcaaacaa cacgacttct
    16381 tctagttcgt ctacagaaag ttcaaaaagt acatctactg cggaaagcac gactgccagt
    16441 agcgtcgatt tgaacgcatt ggaattacca caattgacga aagatgtcgc cgaaaatgaa
    16501 gatctggtcg aaatggtgac gaataaaggc acaatcaaaa tcaaattatt tcccgaacac
    16561 gcaccaaaag cggttgaaaa ctttatgaca catgcaaaag acggttacta caacggactg
    16621 actttccatc gcgtcatcaa agatttcatg atccaaggtg gcgatcctaa aggcgatggc
    16681 actggagggg aaagcatttg gggagaagga tttgaaacag agatcaacaa ccacctttat
    16741 aatataagag gtgcgttatc tatggctcgc tcacaagatc ctaacagtaa cggcagccag
    16801 ttctttatcg ttcaaaatac agatgatatg catgatggtc ttttaaaaga cgactatcct
    16861 caagcaatca tcgacgctta taaaaacggc ggttatcctt cactagatgg ccattatact
    16921 gtcttcggcc aagtgattga aggaatggat gtcgtggatg ctattgcaaa tatcgaaaca
    16981 gatagttcag acaaaccaaa agaagaagta aaaatcgata aaatcaatat actgcaagaa
    17041 gcaaaacaaa aataaaaaaa taacgtctga atcctgcata gatgacaacg tatgctagga
    17101 ttcaggcgtc ttctttttac ataaaaagca agtaagcttc cttttgtttt gctatatcag
    17161 gttttatagt caagcatttt ggttgacgat gaacgtgaac tcgcactcac agactttttt
    17221 atcatctaca tatgctgcag ataacgctgt accgactgat cccttcattt tggtgatttc
    17281 aaaatgacat ttcagcacat ctcctggaac aactttttga cggaatttgg ccttattgat
    17341 cccaccgata taagctcttt ttcctagaaa ctcttctgat tttaggataa gtatcgaacc
    17401 tgcttgtgcc agtgtttcta gaatcaacgc acccggcatc actggattgt caggaaagtg
    17461 accttggaaa aaatcttcat tgattgttac attttttgtc gcaacgatct tttttcctgg
    17521 ttctaaagta tctacataat caatataaca aataggataa cgattaggaa tcaattccat
    17581 tacttcagta gcagataata cgtaagacat aattaaactc cttctttcag gcaattgcca
    17641 ttttcattac tttgactatc aaagtatcat attcctaaat atttagcaat ctttttttaa
    17701 tttaagaaaa aatagtttga caatcaaaac attttgacta ataattaaga aatcaagaag
    17761 ttattttagc tattattctc tattttttta cgactatcaa atttttatca gaaacaaagg
    17821 agagtcatta tgtcatttct agaaggaaaa aaaatcgtca ttatgggcgt cgctaacaaa
    17881 aaaagcattg cttggggttg tgctgaagca atgttgaaac aaggggcaga aattatctat
    17941 acttaccaaa atgaacgaat gaaaaaatca ttagtcaaat tggtcggcga agaagcattc
    18001 actgtagaat gtgatgtttc tagcgacgaa agcatcgaaa aagcaatgaa tgccatcggt
    18061 gaatatgctg gggagatcca cggccttgtc catgcagttg cttacgccaa caaagaagaa
    18121 ttgtccggaa atgtgtctga tatttccaga gacggctatc aattagctca agatatcagc
    18181 agctactctt taattgctgt atcaaaatac gcacaaccgt ttcttgcacc aaacagcggg
    18241 atcgttagca tgacttatct aggttcagaa cgcgcaatcc cgaattataa catgatgggt
    18301 attgcgaaag cttctcttga agctgctatc cgttatttgg cagctgagtt ctcgcctaaa
    18361 ggaattcggg tcaatggaat ctcagctggg gcaatcaaaa cattagctgt cacaggtgtt
    18421 aaagactatc aaaaactgat ccagttatct gaatctcgta cgcctgatca gcaaggtgtg
    18481 acgatcgaag aagtcggtaa tgcttgtgct ttcttaatca gcccactttc cagcggaatc
    18541 atcggtgata ttatctacgt tgacaaaggt gtccatcttt cataaacttt tgttgcattc
    18601 tttaaagtaa aacatataaa aatcaggaaa aaacttttta aagtctcttc ctgatttttt
    18661 ctttttacgt ttttttcaac tcattacttt gaaattattc cacgacttca atccagcctt
    18721 ctggtgcttc tatgtctcca aattgaatac ctgtcaattc atcatacaac cgttttgtta
    18781 ctggtcctac ttccgtttca ctataaaata catgaagatt gttattgtga taaatcccac
    18841 cgattggaga aataacagcc gctgtaccac atgcaccagc ttctgcaaat tgatctagat
    18901 catcaatgaa aatatctcct tcaattgctt gcagtcctag tcgttcttca gctaactgca
    18961 acaaggaata tttcgtgata cttggtaaga tagagggcga ttgcggagtg atgaattttc
    19021 cgtcttttgt aattccaaag aaatttgctg cacctacttc ttcgattttc gtatgtgtgg
    19081 ctggatcaag ataaacacaa tctgagtaat ccagttcttt tgcttctgtt cctggaagta
    19141 aactcgctgc gtaatttccg ccgacttttg ctgcaccagt ccccttagga gcagcacgat
    19201 cgtaatcaga tacaataaaa ttcgttggtt ttagtccacc tttgaaatac gctcctactg
    19261 gcgtacagaa gacgacaaat aaatattctg gagctggatg gacaccaatg ttttcaccga
    19321 ccccaatcag taaagggcgc aagtataatg tagcgcctgt tccatagggc ggcacaaaat
    19381 cttcatttgc ttttaccact tgcttgacag catcaacgaa catcttttca gggaccattg
    19441 gcatcagcaa tcgtctagca ctttgattca tccgtcgact attttgttca ggtcgaaaga
    19501 gattgacctt gccgtctttt cgacgataag cttttagacc ttcaaaacat tgctgaccat
    19561 aatgaagcgc tggagagcct tcatgaatcg tcaggtaatt atcttctgtc aattctcctt
    19621 cttcccattg tccgtctttc catttggcaa taaaacgcca aggagttttg atataagaaa
    19681 aacctagatt gttccaatcg atttgcatat acttaccacc ttcgttattt tctccacatt
    19741 ttatcattat ccatattatt tgtcatttta ttttcagctt ttttccttca ttatagttat
    19801 ttttgctatt tccttttttg aaaacttctt ggtacaatac agaaagaatc aaattttaga
    19861 aaagaggatt ttatgttttc attattagca actgccggta cgacagactc ttctggcgag
    19921 acattgacag atcaagctgt cagcaaagta aatgcgtttc agcggttttg ggacgggatt
    19981 gattgggacg ccattttggc tgcctttatc caaaaaagtt tatatctgat ttttttgatc
    20041 gtcctttttt ggattcttca ccgtgtggga aaatatctga ttgataagtc ttttaatcag
    20101 tattctaaaa aagccattct aaacgagagc cgcttaaaga ctttacatag tcttttaaat
    20161 actatttttc attataccct tggtttcttt tttatctatg caattttatc tgctatcggt
    20221 gtgccgatcg gatcactttt ggctggtgcc ggaattgcag gtgtggcaat cggtcttggt
    20281 gcccaagggt tcatgagtga tgttattacc ggatttttta ttatcatgga acaacagatg
    20341 gatgttgggg actacatcaa gctagcaaac ttaacgattg aaggaaccgt cgtatctgtt
    20401 ggtatccgta cccttcagct gaaagcaacg gatggtactg tccatttcat cccgaatcga
    20461 aacatcacca cgatcagcaa tctctctcgt gcaaatatgc aagtactttt agatattcgg
    20521 attgttcctg aagaaggata tgacaaaatc tatgagatca ttgatcgagt aaatcgtaca
    20581 ttagctgaaa aataccaaga agagctccaa actgaacctt ctatctttgg attagtggat
    20641 cttggaaaca gcaattttgc gattcgtacg gtctgctacg cattgaacgg aaaacaatat
    20701 gccttaaaag aagagttctt gagctcctat gtcaaagaat tgacagcttc tggtttcacg
    20761 attccgaaca gtccaattgc tgtcggaaaa taatttggac aaacgatgca acgaatctca
    20821 ctaaaaagag cgtgggacaa aagtaaagaa cacttttgtc ccacgctcta aacacgtata
    20881 aacggcggaa gcagaagcaa ctccttcgga aataagctga aattcacaaa aatttgaaaa
    20941 gcaattttcg tgaattcctt cttatttctt ggagttaaac gcttttgtcc cagcctcttt
    21001 ttcaagataa agtcaaaact ggtacgctgt tttttctact tattttttga ttatctttta
    21061 gtttctcgtt ctttagctca cgatatcgat ttgttctttt aattcttcga ttttcggaga
    21121 caatatatta cgacgttcta attcatgcac catgaagttt acggctttaa gcagctcttt
    21181 tcttgtaatg attcctttga aaatccgatc ttctgtgaca accggtaaaa aaggcgaatc
    21241 gactaacaaa tggagtactt cttctagttc ccaattttca tcaattgtcg gaacatctgt
    21301 ttctgtcaca tcagcaaccg ttagtccttc taacgggtcc atgctgattg tttgcaagtc
    21361 aatcatttta ttgaccacat ctgataaact tactagtcct acaaagtgat catcttttcc
    21421 taatacagga attttggaat aaccgacctt cgataacaca agtaaaccat gggacaatgg
    21481 atgatgatac ataacatttg ccacattttc tgcaggaatc aaaaacgttt cctgattttc
    21541 cagcagcatt tctcttacta taggtccaat catctgatgg cctccatttc tatttcattc
    21601 aacactacta ttttaccgaa accggatgca aaattcataa aataaagctt atttttatta
    21661 aaaattagag tttttttatt cagcgctctc tcgaaaaaga aaaggccaac tcttcaactg
    21721 cctgatgggc acggttatag tattgaacag aaatttggtc atctaaactt tcgataagag
    21781 catatgatgg gatttggatc gggcctctag gctgagaaat gctaccagga ttcaaaaaca
    21841 ggattttctg atccatctca cagcctattt gatgggtatg accaaaaaac accatatcgg
    21901 cagttgcagc tcgagcttcg attgctaact gtgtcaaacc aaatcggaca ttcgataaat
    21961 gaccgtgagt catgaatact gtatcctgac cagtttggat cacttttttc tgttcgaatc
    22021 ctggtccata atcacaatta ccttgaacca cttggaatgt atcccataat gggtcagaag
    22081 cttctaattc cgaatcacca caatggaaaa agatatccac ttcagaacga taacgatcta
    22141 ctaagtcaac gaggatatct ctgtctccat gattatcact tactactaaa taccgcatct
    22201 atctctctcc ttccagccat tgtttccact cggcactcaa ttttttcatt gcttgagccc
    22261 gatgactgat cttgtttttt tcttcgctcg ataattctgc tgctgtttgt ttcttacctt
    22321 ctgggataaa taaaggatca tacccaaagc cattttcgcc agatggtata cgggctactc
    22381 gaccgggcca ttccgcttct actacaaggc tgtctttttt gggtgccgcg aatactaacg
    22441 tacaatggaa ttgtgctgtt cttttttcat ccggcacatc tgtcaattca tataataatt
    22501 tggcgttatt ccccgcatca cttttttgtt cccctgcaaa acgtgcagaa tagattcctg
    22561 gcataccgcc taaagcatcc actttcaaac ctgaatcatc tgctaagact ggctgatcaa
    22621 gcaattgtgc aatcgtttct gcttttaatc gggcattttc ttcaaatgtg ctgccagttt
    22681 cttccacatc tggcaattca ggatagtcaa gtaatgtttt tacatgatat cccgcttctt
    22741 tgaacatatt tcgaaactct tctgcttttc ctggatttct tgtcgcaatg atgattgttt
    22801 ttgtttcttc tatccgctca tcattttgag caaactctgt tagcaaagca tgtttttgct
    22861 ctttgatcaa atcttcaatc gcgttttttc caaaaaagag catttcattc aactgttcac
    22921 catcaaacgt tgcttcttct ccagttcctt gaatctccac gaattttcca gattctgtca
    22981 ttacaagatt catgtctaca agtgctgcgg aatcttcttg gtaatccaaa tctgtgacgc
    23041 aagtcccatc tggtaagatt cctacgctaa ctgcagcaag atgttctttt attggatctt
    23101 ctgacaattc tttttctctt aaaagttttt caatggctaa tttcaatgcc acaaatgccc
    23161 cagtgatact tgctgttcta gtaccgccat ccgcttggat cacatcgcag tctacgatga
    23221 tactacgttc tcctaatttt tccaagtcta ctactgcacg caaggaacga ccaataagac
    23281 gctggatttc cattgttcta ccagaaagtt tccctttgct gctttctcta cgatttctcg
    23341 tactcgttgc tcgaggcagc atactatatt ctgctgtcac ccatcctgtt cctgtttctc
    23401 tcaaaaaagg gggaacagaa ttttctattg ttgcagaaca aataactgtt gtatcaccaa
    23461 aacggatcac taccgatcct tctggatatt tgaaaacatt tgtttgaagc tccagtttgc
    23521 gaagctcttg ggcttttctc ccgtcatgac gcatccttat tttcctccca attcgatatg
    23581 ttctacattt aagtgtccga ttccaagcca gtcttcagct atttcctcga aaagtttggc
    23641 agagccagtt gtataaaact ggcataatgt ccgaccattt tgcggtgaat tgctcaaatt
    23701 gaaataatct aacagcatag atacttcacc tactgtttct gctccagaat cgatcagttg
    23761 aacattttct cccattacat tttgaatgat ggggcgtaat aatggataat gggtgcatcc
    23821 caaaatcaat gtatcgattt ttttagtggt taaaggagct aatgtttctg ccacaatttt
    23881 tttcgccacc gatgaatggt attcattact ttcgacaact gaaacaaatt tgggacaagc
    23941 aagacttgtc acagtcaatt ctggtacttt ctctttcagt gctttttcat aagcttgact
    24001 ttttaccgta ccaatcgtac cgataatgcc aacttgttta ttttgtgttt tttttactgc
    24061 cgctctagta ccgggaagga tcacaccgat gactggaata gaaagagcag ctttgatttc
    24121 ttctaaagcc accgcagttg cggtattgca ggcgatcacc agcatcttga ttccttgctc
    24181 caccagataa tccgtcattt cccaagtata ctggattacc tgttccgcgg gtctagggcc
    24241 atatgggcag cgtgctgtgt ctcctacaaa taaaatattt tcattcggta attgtttcag
    24301 ggcttctttt actacagtca agccgccgac acctgaatca ataaatccga tagggcgatt
    24361 atctgtcaat cgtatcatcc tttttttcaa taaattctat cctccctatt gtgtactttt
    24421 tagcgtgaat tttcaagtgc tcttacttgc ttaaaacaat cgaaatctct ttttttcgaa
    24481 tggaaagagg aaaagcggtt gtgactttag tttgccacaa ccgctaaaag aatcatctat
    24541 taataactgt accgtctctt ttccaagtaa ccggaaagca gagaaagcgc gtaacatacc
    24601 acgaagtaca taagtgtcat gatgatgaac atcggaagca cataattggt gttctgtcca
    24661 taaataatac gtgcctgatg agaaagttca ggtaaagaaa tgattactgc taatgaagta
    24721 tctttgatca gtgaaatcaa ttggctcaca attgccggga tcattgattt aaatgcttgc
    24781 ggtaacacga tcgttcgcat cgattctaca taagtcagtc ccgttgataa tcctgcttcc
    24841 atctgtcctt ttggaacagc attgagtcca gctcggaaaa tttccgacaa catagctgac
    24901 tcaaaaatcg ttaatgctgc gacagcggac cagaagatgt tcatctgaat gccgatttga
    24961 ggtaaggcaa agtaagtgaa gaaaatgatc aataataatg gaagattccg tataatatca
    25021 atcactacac caaggatttt ggaaaagaaa gggatattcg caaaacgaat cacacctgtc
    25081 agaccaccga tcaagaaact aaaaatgatc gaaaacaatg aaacttcaac agtaaccttt
    25141 aatccttcca ataaaaaacg gatattcatc catgaaaaag cgccgctaaa atccatgtat
    25201 ttcccctcct tctatgaacg aaccgcccat tttttctcaa gataaaccat taagtaagat
    25261 aacggtagcg tgataactaa gtaaaataac ccaacgatga tatacgtatc gaaggtattg
    25321 aatgtttcac tagcgatcaa gtctccttga tacatcaaat ctaaaccagc tacgattgct
    25381 aaaatagatg agttttttac gaggttgata aattggttgc ctaatggcgg gataacgatt
    25441 ttgaatgctt gcggtaaaac aatataacgc atgatttctg aataggtaaa accagaagat
    25501 agtcctgctt ctgtttgacc ttttggtacg gtttgaatcc ctgaacgtac tgtttcagca
    25561 ataaaagcag atgtatagat cgttaatcca atcgtacctg cttggaatcc atctagatta
    25621 aaccaataaa tcggtacgac aacataaaaa aacatcacga tgattaataa tggaatgttt
    25681 ctaaaaaatt ctacatatgc ctttgctaag gcgctcacta ctttattctt tgataattgg
    25741 aagattgcca ttaacgttcc gataatcaaa ctaaacacaa gtgctaagac actcgaaaac
    25801 aatgtgatct tgaacccgtc gacaaagatt ggtccataag tttgtatcaa ttcgctcatt
    25861 gcctctcccc cttactctac ttttccttca gtttcatttg gaaaccattt ttgatagatt
    25921 ttatcgtatg tgccatctgc atgcatttcc tctagcgctt ggttaacagc tttcaagaag
    25981 ttttcttgcc ctttgttgat cgcaatcccg taaggctcat tagtaaacgt tccaccaact
    26041 aactcatact ctggattttc atctgcaatc cctaacaaaa tcgcattatc cgtagtcatc
    26101 gcgtctccct gaccagattg taaagcagta aatgcttctg catagttttc taattctaaa
    26161 atttttgcat ctggtgcatg ctgtcggata ttcgcagccg atgtagaacc tttgactgct
    26221 agaaccgttg tagaagcatt caaatcatct acacttttga tttggcttcc tttctttacc
    26281 aacaaagctt ggccagcatc gaaatagaca tctgaaaagt caacctgttt ttttcgttca
    26341 tctgtgatcg tcatcgttgc aataattgca tcgatatttc cgtttttcaa taatggaatc
    26401 cgagttttag aagtgacttc aacaaattct gtttttccat tgtcaccaag gatcttttta
    26461 gtgattgctt ttgcaatatc tacatcaaat ccttgtacag ttctgctctc aatatccatc
    26521 attccaaata atcgagtatc atacttgaca ccccagatga tttcattggt agatttgctt
    26581 cgctctaaaa tatcttcatt tgccaaccca tttcctttac atccggctag tgcaagaaaa
    26641 gcaatgccta aaaggaaaat caggcgtatt ttttttaacc tgcgcatctt tttcctccta
    26701 tcaatgattg ataactttac tgataaattg ctgtgctcgg acttcatttg gattttcgaa
    26761 aaagtctctc acatttctgc tgtcttccaa tacttctcca tcagccatga agataacacg
    26821 atccgccact tctttggcaa agcccatttc atgtgtcacg acaatcattg acataccgtc
    26881 atgagccaat tttttcataa cgtctaatac atcaccaatc atttccggat ccaaagcaga
    26941 agtaggttca tcaaacagca gcatctcagg attcatcgct aaacctctgg cgattgccac
    27001 ccgttgctgt tgtcccccgg ataacatgga aggataagaa tctttcttat ctaacatatt
    27061 gacagttttc aaaaatttct ccgcgttttt gactgcagtt gcctggtctt gcttcaacac
    27121 tttgattggt gctaatttga tgttttccag aacagtttta tttgggtaca aattgaaatg
    27181 ttggaaaacc atgccgatgt tttttcggac ttctgtcagt tttgtctttt tatcatgcaa
    27241 gtcagtatca ttaatcagca gcttacctga agagatcgtc tctaatccat tgatacagcg
    27301 aagcatcgtg ctctttcctg aaccagaagg accaatgaca acgacaactt ctcctttctc
    27361 gaattcgaga ttgatatttt ttaatgcgtg gaacttgcca taatatttat ccacgtgatc
    27421 aaatttaatc attgccatag aattacactc ccattattat ttagtaagat ttcttttaaa
    27481 gatgtataat aaaatacatt atatctgata gtttagtaat ttgtaaagtt tcttagaacg
    27541 tttattctcc cataaatatt tcttccattt ctaatctatt agttatttta tcctctttcc
    27601 ttgttttttc cttaggaact gttgtttctt ttcaggaaaa acggtaagat attaagtgct
    27661 cagacttaca aatcgtaaag aggtgtcttt tttgaaaaat attattttaa cgggagatcg
    27721 accaactggg aagctgcatt tagggcatta cgtcggttct ctaaaaaccc gagtggctat
    27781 gcaggcagat gaagacaacc aactgtttgt catgattgct gacatgcaag cactgacaga
    27841 taatgctaaa aatcctgaga aggtttcatc aaatgtcttg caagttgctt tagactattt
    27901 agccgtggga ttagatcctg caaaatctac tttatttatc caatcacaaa ttccggaatt
    27961 agctgaatta accatgtatt atttgaactt agtcagcgta ggacgcgttc ggcgcaatcc
    28021 gactgtcaaa acagaaatcg aacaaaaaaa attcggtgaa agcgtgccta caggattctt
    28081 tatctatcct gtttctcaag cagcagatat cactgcattc aaagcgaatc ttgtacctgt
    28141 tggtgaggat caaaaaccaa tgctagagca gacacaggaa atcgtacaaa gcttcaatca
    28201 tacatatggt gaagtcttgg tggaaccaaa aggcgtattc ccaccaaaag gaatgggtag
    28261 attacctgga atcgatggaa atggcaaaat gagtaaatcg ttaggaaacg gtatttatat
    28321 ctccgatcct gccgatgtct tacagaaaaa agtcatgagt atgtatactg atccaaacca
    28381 catccatgta caagatcctg gacaagtaga agggaatatg gtcttcacct acttggatgt
    28441 attcggaaca gataaagaag caattgaaga aatgaaagct cattaccgcc gcggcggact
    28501 tggtgatgta aagatcaaac gatacctcat tgatgtattg gaagctgaat ttgcaccgat
    28561 ccgtgcgcgc cgagaagaat tggaaaaaga tccttcagct gttatggaaa tcttacgtaa
    28621 aggtagtgaa gaagctgcta aagtagctgc acaaacactt tctgaagtaa aatcagcaat
    28681 gggaatcaat tacttccatt aattcattta ctctaaaaaa gcaggctgta aaggcctgtt
    28741 tttttatctc gtctctgtgc tattcctttt ttaaaatcaa aaaaagagat gtgacgaagt
    28801 tgtgtcacat ctttttttca aatgtatggt cttcaaaagc tacttgatcg ttacttacta
    28861 tattttcctt cttagcgaat acttgcctct aggttttcta ccaacgcttt ttcgactttt
    28921 tccattgctt tattgatttc ttcatctgtc aatgttgctt ctgggttgac gaatgtcagg
    28981 ctatacgcca tggatttatg tcctttttca atgttttctc cttgatagac atcaaataat
    29041 tggatatctg ttaaaaatct tccggcagca gaacggataa cttctgttaa ttcctgattt
    29101 gtcacagttt cttttacaag caaagcgatg tcccggctga ctgctgggaa ttttgtcact
    29161 gcttcgaaaa cgatcccttt ttgagcagct tccactatag cagataaatc aaactcagca
    29221 acatatgttt ctggaatatc ataacttttt gtaatcgttg gatgcacttg accgacaaaa
    29281 ccaataaatt tttcgccaag gtaaatcgca gcagttcttc caggatgcat ttccttcatt
    29341 tctgtcactg tttgataatg gacatcttca gtgatgccta gttgttcaaa taagttttct
    29401 aaaagaccct tgatggtgaa aaagtctaca ttttgagctt tcgtctgcca atctttttct
    29461 tcccaaatac cagaaatagc gattgctgca tgttttactt cttgcggcag atgtgtacgt
    29521 ggatcatttt cttggaagaa cacccgacca atttcatata aagcaatctc tgtatttttt
    29581 cgggcagtgt tataactgat atcatctaat agtccgctga tcaaattcat tcgtaataca
    29641 gaacgttctt cgctcattgg ccagtccaaa cgtgtaatat tactttcatt tataacaaac
    29701 tgtcttgatt tttcttctgt tgtcaatgca taactgattg cttcgctcaa tccgcttcct
    29761 tcaaagattg tacgaatttt acgagtagtt tcttgttctt ttgacaagct tccagcaacc
    29821 gtttctccac ttggaagtgt agatggcaac tggtcgtatc cataaatacg agcaacttct
    29881 tcgataatat ctgcttcgat ttggatatcc cagcgtcttg gtggtactac tacggaataa
    29941 acatactcct tttcttcata gctaaatcca agtgcttcaa aaatctcatt tacttcttta
    30001 acgacaagag atgttcctaa atattgattg atgcgttcaa gtgaaatctt cactgatacg
    30061 tcttctgctt tgatctctga gcctttgacc gcgccttgta gaacttcccc acccgcaaga
    30121 gaaacgatca ttgctgcagc aacctcactg gcttctccaa cagtcgcatg gttgattcct
    30181 ttttcaaaac gtgcagagga ttcactacgc aaattaaatt gttttgctgt acgacgaatc
    30241 gaaattggat caaataaagc agattctagt gcaactgttg ttgtttcatt cgtgatctct
    30301 gagtctaacc ctcccatgac accagctaaa gcaactggtt ctttgccgtt agtaatgacg
    30361 agattgtcag ttgtcaattc ccgagattct ccatctagtg ttactaatgt ttcattttct
    30421 tttgcacggc ggacaaagat ctcttttgat ttcaatttgt cgtagtcaaa tgcatgtagt
    30481 ggttgtccga ataaaagcaa aatatagttc gtcacatcta ctacattgtt gattggacga
    30541 atgccttcgt tcatcaaaag attttgcagc cattgaggac ttggctggat tcttactcct
    30601 tcaatgattc tgatttgata agcaggaact gcttctttat cttcaacttc cacttgaatt
    30661 ttatcgctag caggacgtga ggattctacc agcttttcgt catcgaatgt aggagtctga
    30721 cgataaattg ccccaacttc ataagctacg ccacgcattg acaatgcatc cgcacgattc
    30781 ggtgtgatag ataattcaat aatcgaatca tccatatcca aataaggaaa aactggatcg
    30841 ccatttacag cttcttgtgg catataatag ataccttcag cgtattcttt cggtataaca
    30901 ctatctgaat agccaatttc ttgtaatgag caaatcatgc catttgatac ttggccacgc
    30961 atttttcctt ttttgatttt tacattacca gcgatacgtg agttaggaag tgcaacaatc
    31021 actttgattc caaccttcac attaggcgct ccacaaacga tttgagacag ttcgtcttcg
    31081 ccaatatcga cttgacaaat agaaaggtga tcagaatctg gatgtggtac gcattccttg
    31141 acttcaccga caacgatttt tttcaagcct tcttctggaa ccgttactcc ctctacttcg
    31201 attcctgtca cagacatctt atccgctaat tcttttggtg ttacattcga taaatctaca
    31261 taacgattga gccatttata tgaaactaac attttcttac tcccccttga actgacttaa
    31321 gaaacgtaag tcattttgat agaaattacg gatatcattc actccatacc gcaacatagc
    31381 tacgcggtct ggtccaaggc cgaaagcaaa gcctgaatat tcttctggat cgattcctga
    31441 catcttcaac acattcgggt gtaccatgcc agctcctaaa atttcgatcc atccagtgta
    31501 tttacatacg ttacaaccgg caccaccaca tttgaaacag ctgacatcta cttctactga
    31561 tggttccgta aatgggaaat aacttggacg caaacgaatt tcacgatctt ccccaaacat
    31621 ttttttcatt acgacttcta atgttccttt aaggtcgccc attgtgatgt ttttatcaac
    31681 aactagccct tcaatttgat ggaactgatg actgtgggtc gcatcatctg tatctctgcg
    31741 gaagactttc cctggcgaga tcattcgtag agcaccctta gagaaatcat gtttttccat
    31801 tgtccgtgct tggactggtg aagtatgtgt ccgaatcaat atctcgtctg aaatatagaa
    31861 agtatcttgc atgtcccttg ctggatgatc ttttggcaga ttcatccgtt cgaaattgta
    31921 atgatcagat tctacttcat atccttctac gatctgatag cccataccca caaaaatatc
    31981 ttcaatttct tccatgattt gtgtcacgat atgacgtgta ccatgtttta cttttctacc
    32041 aggtagtgtc acgtctattg tttcttttgc caaagctgca tttaacgctt cttcttctaa
    32101 tacttgtttt tttcgctcga tctcttctgt caaaagatct cggatctcat ttgcgaaact
    32161 tccgactttt ggtcgctctt ctggacttag atctttcatc ccacgtaata cttctgtgat
    32221 cggtcctttt tttcctaacg tttcaacacg tatttgattt aattcattta aatcttgtgc
    32281 cgctgtgatt ttgacgagcg ttgcttcttt caagctctct aattgtgctt gtagagacat
    32341 gtgcttgttc ctcctttaaa ttccaaatac aaaacaaaaa gacctcattc ctgttaagga
    32401 acgaggtctt cgcgttacca tcctaatttg cggataaatg acttacaccg cactcttact
    32461 tcgttaacga caattgccgg tctgatttta tcagacgaac tcggaaagtg aacttcattt
    32521 ttcaaacaca ggatctgctt tcagtctgcg acagatctcc ctgaactggt ttagccaaac
    32581 tactcttttt cgtcatcgtt ctttacttat tcgtatggac tatagtttac aagatttttt
    32641 ttacaaaatc aaccgcattc ttcctctgtg atccattttt cgctccaaac ttgtatttga
    32701 cgcatcgctt tttgcaagtc tgctcctttt tcagtcaaga gatattctga acggctcttt
    32761 tcgctacagg caaagtttcg agtgactatt ccttcttttt ctaattcctt caagcgttcg
    32821 actaatactc gatcactgac catcgggatt tttgccgcaa gctcaacaaa gcgttgcgga
    32881 ccgttttcga gtagtacatc gataatcaat ccgttccatt tttttcctaa aatagagaat
    32941 gttttttcaa atttagggca taaaacgaat tctgtctgtg ttagctccat catactcacc
    33001 tcttcccaga gtatagcata atccttacaa aacataagtc aagtttgctc aattataatt
    33061 atttgttaat gtttataatt tgtttcactc gaagcaaaat taggaaaaca ttttctactg
    33121 gcttattcaa agcttctgac attgcttgtt ggtaaagtct tagctgtcct tgatattttt
    33181 ggacgattgc atctatttct gctggatcat ccggatgtaa aataaaatct gttttaaaat
    33241 catagatatt gagatgatct ttttcttcta ggtatccatc gacgattccg tggattaata
    33301 gttcatcttc ttgatttgga tagtcttgaa atacttcgtc agcaggaagc agcatggaaa
    33361 aaggttgttc tcgttttacg ttttctttgt tggcaatcag ctgttgacca agttctgttt
    33421 gaaagaacca tataatagaa gaaacatcta cttttttcgc gactttttcg tctactaacc
    33481 gtttccttac caattcctgt aatttttgat ggatactctc tgtagttggc atctctaatg
    33541 gcagtaattg taacaaagca tgcgtagcag ttccaacagc agctgctgac acttgccgat
    33601 ctttttgcaa aaattttggt tctgctagtt gttcttgcgt ataacgaaat tgacgggatg
    33661 ctgctttgtt ctgactgctt tccagagtca aacgtgattc ttgtgtatca tctggatctt
    33721 cgaataatcg tttgatttca gatacagatt gataacttgt ggtttgtgaa gaagcttgat
    33781 aaggatattc atatgccaga cgtttttgta acgaatctgc taataaagtt tcatcttctt
    33841 tcatctgctg atctaagtta accagttctt tttcagcaag caactgtctt tgttcaatga
    33901 tcgattgctg attcatccat gaaatagaaa actgtgcatt tgaatgttga agaagagaag
    33961 tcgaaatttc ttcctctaag tatttctgca tttcaggatg acggatcaat ccgtaaccaa
    34021 tccaattcat caagctgctt ctgcccttca aacgtagcgc aggatcaaaa actaactcct
    34081 catgatcagc tgcttcagac cacgtttgga tcatttgctc tttattttta taggaaccga
    34141 caatgaaaag cttttgttct gcccgagtca atcctacata caatttacgc atttcttccg
    34201 acaacaattt gttttgcttt gccaatttga tggcttgaaa cggtaacgta tcatataaca
    34261 ctcgtgtttc aggatccata tagcgaattc ctgctccaag tttttcttca aaagcatacc
    34321 gattgcgcaa gtcttgtaag ttgaactcct ttgtcatatc taacaaaaat acaactggga
    34381 attccaagcc tttacttgca tggatcgtca taacgcgaac agcattatct tctattgaaa
    34441 tgactggttc tgctaagtct ttatcttttt cttgcatttt ttcaatgaaa cgcacgaact
    34501 ggtataatcc tctgaaagaa ctttgctcgt aagctttggc acgatcaacc aatgcataaa
    34561 gattggcttg tctctgtgcc cctgctggca gaccgaccac atactctaga tatcccgtct
    34621 cataatagat atcccataac aagtcagtga tcgaagaacg gcgagcaagt tctcgccaat
    34681 gctctagttg cttgccaaaa tgttccagct tagctgctaa ttcatcttcg tttgatgctt
    34741 gataagcaag cacagcatca tagtaagtat gtgcacggtt agctaatcga atgctggcta
    34801 attctggttc aatcagaccc acgatcggtg agcgcaatac agccgcaagc ggaatatctt
    34861 gatagggatt atcgattaat tgtagcagcg agatcatcgt gcgaatttct gtcgcttgaa
    34921 aatagttttg agcatcattc atctctaatg gaatatccaa tgttttgaaa atctctaaaa
    34981 tcgttaagtt gttcttcttt gtaggtgtca agagaacaat gtctttgtac tctatcggac
    35041 gacttttttt tgatttttta tcataaatca taaaggagga atcaattaat tgacgaattt
    35101 ttagtcctgt cataaaaagt tcgccttctg ttttgtcttc cagtatatca tccgtcggaa
    35161 tctcaatctc tgattcttcc tgttcttttt catagatcat gatttccggc tcaaactgtt
    35221 cattctctgg aaagtctgaa aatccttgga tcagtttggc tgcttcgtca taattgattt
    35281 gacccactgc tggatccatt agttgttcaa aaataagatt cgtaaaagaa aggacttctt
    35341 ttctagagcg gaagttctca gccaaaacga ttcgacgtcc gccttctttc tttgagaaat
    35401 tctcgtattt cccgataaat aaactaggat ctgctaaacg gaaagaatag atggattgtt
    35461 tgacatcccc aaccatgaac atatttcctt ttgtatcatc gggttctctt agccagtata
    35521 aaatggcttc ttgtaattgg ttcacgtctt gatattcatc taccattact tctttgaatt
    35581 tttttcgata atgttttgaa gcttcacttg gcagccatac atctttcgtt ttttctgtga
    35641 gaatctgcaa cgctaaatgt tccagatcat tgaaatccag cacacctttt tcccgtttac
    35701 gcatactgaa accgtccatg aagctttgcg tgacttttgt catttcttcg actaacggta
    35761 gtgctttgtc cgttaattct tccatttggc ttggggaaac aggaaaataa cttttactta
    35821 tctgctgaat cagttttttt gctttatccc tcatgccctt gacttcattg gaaatttctt
    35881 tcaattctgc tttccgactg ctcttaaaag ttgaaaaagt tagttgttcc aaaccagcat
    35941 aagcttcttc taaccgatct tgcgagaacg cttcatagat attcttgatc tgctgttgtt
    36001 ctccagctac ttgctcatgc attttttcta atccttcacc ttgtgctaac tgagtcatct
    36061 gttcatataa ctgtacacat tggtatatat ctgccaaaac taaaggacgg atttgttttt
    36121 gatataatcg agatttcgct agcccctcag gcaaacgata attatcgctt aactgttcta
    36181 gccatttttg ggggtcaggg ttggcacggg caaactcata aagagaaaac accagattcg
    36241 tcaagccgtc atctgaacga tcattagaaa aattcattgt taattggaaa aatcgttcat
    36301 cattttctgc ataaagtgct tctctcagct cgtcccacac atcctccttc atcaagatcg
    36361 tttctgtttc atctgttaac atgcgaaaga ctggatcaat atcaattaag taataataac
    36421 gtcgaataac tgtcaggcaa aaagcatgta aggttgagat attcgctgtg ggcaataaaa
    36481 ctaactgctt agtaaaatgc tgtctacgta cagggtcact ttcgctattg acggattctt
    36541 gtaatgcctc ttgaattctt tctttcattt ctcttgcggc agcttcagta aatgtcacaa
    36601 tcaataattc atcgatatca aaacccattt ttagtttttc aatcactctt cgaacaagca
    36661 ctgtagtttt acctgatccg gcagacgcag agactaatag attatctcct tgatcaaaaa
    36721 tcgcttgcca ctgatcatct gtgaatcgtt cattttgcgg ttttaaagga atttgattca
    36781 ctcttcttca ctccttttca atattctacg cagtgcttct tccttatcta ttttctccag
    36841 acggtggtaa ttattttctt tcagcatcac atcaaacgta cagatgcttc tgaatggaca
    36901 aaattcgcag gcaatccgct gtttatcttt ataagctgga tttagtttga tttctccgga
    36961 agtaatcgca tctccagcta accgcatatt ttcccgatta tgcgccatga atagttgcag
    37021 ttcttcttcc gtgaaaaatt tgtctttact gaaactacct ttttggtatt catctttcgc
    37081 attttttttc actggataga tcagtgattg ttcttttgct tccagtgaat gatctagtac
    37141 ttctaaaaga gcgggatcat cgacaaaaac gccatcataa ctaaattttt tcaatgtatt
    37201 cttctctaca tcatctgtct ccgtcaatac aggattatga acatgtaaat aatatgatcc
    37261 tgctggttta acagccgcct ttccagtcaa acgtaccgca tccatcaatg ctacgtccag
    37321 atacgtcaat aattgcatag ccatgccata ataagcttct gtgacatcga atgaacgtcc
    37381 gctagatttg taatcaacga cgcttagcca agtatcttct tgttcagaag ctacatcgat
    37441 tcgatcgatt ttccctcgaa catggagttt tccaccatta ctcaacggta attccagacc
    37501 tgtgatacct tttgctccag caatctgacc aaatagaatc tctgtctgaa gaggatgcat
    37561 gcctgtattt ttgctctgtt tttgcaaagc ccatgtcact ttttgaatcg tctgtcctaa
    37621 ctggtagcgg atatagttca ttcttgcaga actatccaat atctcaaacc gaagttctcc
    37681 gaatacttcc tgcagcactt tttcagtaaa gtctctacgc tgcgcatcgg acatattcac
    37741 taaggataat tggtttgaaa acagtagctt gaagaaacga tccaatgatt catgataaaa
    37801 atcaccagtt gctgctggag ttagaccata aacagttcgt tctttcaatt tcaaaccaaa
    37861 ttgcatgaag tatttgtatt cacaattata aaaattctcc atacgtgaaa ttgaagtata
    37921 aatctctttt ccataaagct cttccgccat tttttctggc atcgaaacag gaacatttaa
    37981 atgttcctga ctttcaaaaa tctgtaaagc aaaatttcgc catgacgaat tcagtactaa
    38041 ttctttgagc ttttgccagt gctttggtac aggttttttt tcatctaaag ctaatcgata
    38101 aatcctattg actgtattga ttccgcttct gtaagtccct acataacaat tagggtcgct
    38161 ttcgatcgtc aaatgctctt ttctctcgac gggaacagat aaatattctg tgattctacg
    38221 caaataagga gacatcttca gcgaaccatc tgtgtcatag ctttgtgcat aactaagata
    38281 taatcgatct gttccggaaa gaaaaacaag ataggcttgg aaaggctcaa aagagatact
    38341 ttcctttgat gggtcgaata aaaactgtcc atctggcaag gcctgattta atacttctcg
    38401 ttcttcactg gacaacaatc cttttgtctc ttttcggtct ggaaacactt gatcattcaa
    38461 ccctaatgca aaagtgacgg cagcttgatt tggtcgaact aattccaaac gattgattcg
    38521 cacttggtcg attgcggtag ggattttacc ataacttaga ttttctagac cacttgtaat
    38581 gatttcttgg aacagtgacc agtcaaaagc cgattcacca taaattacta catattcatc
    38641 caacagatca atcagcgctc cccatgtctg ctcatggttt cttgccgctt ctaagtttcc
    38701 tctgtctact tcctgattac gccaaaacaa taattgttgc tgtacgccac tttggatcaa
    38761 aaattgataa aaaacatttg cggcctcttg tcctgttttg cttttcttta tttttttcaa
    38821 aaatactggt acagctttct gaaataatcg tctaatcgta tttgactgtt cttccaaata
    38881 ctgtacgtct tcaatctgtt ctgcttcaaa atcatacgcc acaaactgcc agtctttttc
    38941 acgagtccaa taagttcctt gataattgta agcaagtgct acattttcag tgatgtccag
    39001 ttttttcctg aattcatctc gctcttgttt ccattcatca agttcggttt ctgcttccgt
    39061 cgacagaaat aattcagttt tgaaaaaacg cataatatca cttagccgat aagaatagcg
    39121 gtcaagagcg aacagactgt tgatccattc gatcagcgga tgattttcca tcatttgttc
    39181 ttcatcgata taaaaaggaa ttgccatttc ttgaaagatc ggccgaagga tatttccata
    39241 taaagacata ttttttgtca gcacttggat atcacgataa cggtagtttt cttcactgac
    39301 tagtcgtctg atttcaacag ctaattgtcg gacttcttca gttggatttt cagcttccca
    39361 caaatggaga tgctcttgtc cccctatttt gtgtactgcc gctttctttt ggctagatgt
    39421 ctcttcccac attgtttgca gcagttgaag ctctgtcgga cgagtctgct ctggtgcaaa
    39481 tcggtccact aatataggga ctttccgttc tcttgcactt tgaaaaagac ggaaataaag
    39541 ctttccagtc tcatgaaaga gcgtaagtac ttctggaaga tccgctgtat aaggacgatc
    39601 cagcaataaa tcgacaacca attgcccctt ttccatcatt gcctgcagta attgatactc
    39661 ttgaccattg attcgagaaa aaccactgac aataaatttg acgttgttga aatcttgtgt
    39721 ctgcatataa tttgctagta tagatagtgc atcttcattt gttagtgcac gttgagtcaa
    39781 ttcgctgtca taagctgaaa aaatcagctt caagtctttc attttaagtt gctggtcttc
    39841 tgcattaggt gaatcaccaa ataaaagcat caggtcttct ggttgaatat ttcctgtacg
    39901 caattcactg tagagttctt gtaattgacg aataaaccct cttttattga tttctccgcg
    39961 aaagattgtt aattcttcct catttttttc taaaatctgt cgcaagatca ttgcagatcc
    40021 tgattctgat aattcatttc ctgtaagaag agttgtctgt tgcagcaaat accaagccag
    40081 acgataaaaa ctaaatactt gaacgtttgt tgtgctgaaa gttttttttc cgcttcttct
    40141 tcgcatctcc gctaaaattt cttgttcctg ttcgaatttg ctgtagttgg gaacaaggaa
    40201 aaatacttgg ttacttgcat cctggtcgag ccaagcggat gcttcgtcga tcaagacttg
    40261 acggtgatct tttttcccgt ttccaagaat aaattgtaaa gacatgcttt tcctccttca
    40321 acacatgata cggtgctcct ttattatatc aaaaaatact gaacatttgt tctatattct
    40381 tcaaattata tccttttaag gttctgatat ttctactttt ttaagtatac gcaaaaa
//
LOCUS       DADVXE010000018        38367 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.018, whole genome shotgun sequence.
ACCESSION   DADVXE010000018 DADVXE010000000
VERSION     DADVXE010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 38367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.018"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            212..1018
                     /gene="proB"
                     /locus_tag="KB913_001055"
     CDS             212..1018
                     /gene="proB"
                     /locus_tag="KB913_001055"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBB6819435.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1015..2262
                     /locus_tag="KB913_001056"
     CDS             1015..2262
                     /locus_tag="KB913_001056"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBB6819436.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2338..2682
                     /locus_tag="KB913_001057"
     CDS             2338..2682
                     /locus_tag="KB913_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819437.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2799..3125)
                     /locus_tag="KB913_001058"
     CDS             complement(2799..3125)
                     /locus_tag="KB913_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819438.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3740..4942)
                     /locus_tag="KB913_001059"
     CDS             complement(3740..4942)
                     /locus_tag="KB913_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6819439.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            5059..5574
                     /locus_tag="KB913_001060"
     CDS             5059..5574
                     /locus_tag="KB913_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6819440.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5773..6219)
                     /locus_tag="KB913_001061"
     CDS             complement(5773..6219)
                     /locus_tag="KB913_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBB6819441.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6266..7744)
                     /gene="msr(C)"
                     /locus_tag="KB913_001062"
     CDS             complement(6266..7744)
                     /gene="msr(C)"
                     /locus_tag="KB913_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBB6819442.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(8098..8727)
                     /locus_tag="KB913_001063"
     CDS             complement(8098..8727)
                     /locus_tag="KB913_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBB6819443.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(8711..9175)
                     /locus_tag="KB913_001064"
     CDS             complement(8711..9175)
                     /locus_tag="KB913_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6819444.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9662..10930)
                     /locus_tag="KB913_001065"
     CDS             complement(9662..10930)
                     /locus_tag="KB913_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBB6819445.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(11161..11898)
                     /locus_tag="KB913_001066"
     CDS             complement(11161..11898)
                     /locus_tag="KB913_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6819446.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11965..12534)
                     /locus_tag="KB913_001067"
     CDS             complement(11965..12534)
                     /locus_tag="KB913_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBB6819447.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12662..13534
                     /locus_tag="KB913_001068"
     CDS             12662..13534
                     /locus_tag="KB913_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6819448.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13876..14748
                     /locus_tag="KB913_001069"
     CDS             13876..14748
                     /locus_tag="KB913_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6819449.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14745..16703
                     /locus_tag="KB913_001070"
     CDS             14745..16703
                     /locus_tag="KB913_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6819450.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(17035..17886)
                     /locus_tag="KB913_001071"
     CDS             complement(17035..17886)
                     /locus_tag="KB913_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6819451.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            18009..18476
                     /locus_tag="KB913_001072"
     CDS             18009..18476
                     /locus_tag="KB913_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBB6819452.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18739..19221)
                     /locus_tag="KB913_001073"
     CDS             complement(18739..19221)
                     /locus_tag="KB913_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBB6819453.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(19321..20184)
                     /locus_tag="KB913_001074"
     CDS             complement(19321..20184)
                     /locus_tag="KB913_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6819454.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            20782..21657
                     /locus_tag="KB913_001075"
     CDS             20782..21657
                     /locus_tag="KB913_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819455.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(21802..21954)
                     /locus_tag="KB913_001076"
                     /pseudo
     CDS             complement(21802..21954)
                     /locus_tag="KB913_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(22222..23553)
                     /locus_tag="KB913_001077"
     CDS             complement(22222..23553)
                     /locus_tag="KB913_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6819456.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(23702..24415)
                     /locus_tag="KB913_001078"
     CDS             complement(23702..24415)
                     /locus_tag="KB913_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6819457.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            24590..26014
                     /locus_tag="KB913_001079"
     CDS             24590..26014
                     /locus_tag="KB913_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6819458.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            26313..27020
                     /locus_tag="KB913_001080"
     CDS             26313..27020
                     /locus_tag="KB913_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBB6819459.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            27007..27330
                     /locus_tag="KB913_001081"
     CDS             27007..27330
                     /locus_tag="KB913_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBB6819460.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(27419..28456)
                     /locus_tag="KB913_001082"
     CDS             complement(27419..28456)
                     /locus_tag="KB913_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6819461.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(28777..29760)
                     /locus_tag="KB913_001083"
     CDS             complement(28777..29760)
                     /locus_tag="KB913_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBB6819462.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(30175..30945)
                     /locus_tag="KB913_001084"
     CDS             complement(30175..30945)
                     /locus_tag="KB913_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6819463.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(30938..31873)
                     /locus_tag="KB913_001085"
     CDS             complement(30938..31873)
                     /locus_tag="KB913_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6819464.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(32189..33838)
                     /locus_tag="KB913_001086"
     CDS             complement(32189..33838)
                     /locus_tag="KB913_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBB6819465.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(33955..36558)
                     /locus_tag="KB913_001087"
     CDS             complement(33955..36558)
                     /locus_tag="KB913_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBB6819466.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(36570..37619)
                     /locus_tag="KB913_001088"
     CDS             complement(36570..37619)
                     /locus_tag="KB913_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBB6819467.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(37645..37959)
                     /locus_tag="KB913_001089"
     CDS             complement(37645..37959)
                     /locus_tag="KB913_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBB6819468.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(37975..>38367)
                     /locus_tag="KB913_001090"
     CDS             complement(37975..>38367)
                     /locus_tag="KB913_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6819469.1"
                     /translation="DKKSVVEKLSKLLETNGFVSDHKQFQKDVFDRENHMTTGIGKNI
                     AIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLLAIKDTDKGTNHLRILAEL
                     SGRLMDDEFVKRIKDSRNKKELVKALSF"
BASE COUNT        11640 a         7835 c         6676 g        12216 t
ORIGIN      
        1 aaactactcc tattctaaca tatccgaggc tgtaaaagac tttctttaca aattcttcaa
       61 gaaattctgc tatcttaaag taaaccatta attcgttctt tttccaaacg actgcaagtt
      121 gtacaaaaaa actatttttt acatgacttt actcgtcaaa acaagtagaa tagaacgaaa
      181 ttaatgagtg gatatttgat tgaggtgtca catgcgtaaa gaaattaaaa atgcaaaacg
      241 aattattgtc aaagtaggaa caagtacatt gatttatccc aatggaaata tcaatcttgc
      301 ggcaatcgat cagttagctt ttgtcctttc tgatcttaga aatcggggaa aggaagtgat
      361 cttagtctca tcaggagctg taggcgttgg tatgcataaa ttacatttgt cagaacgtcc
      421 gactttgatt cctgaacagc aagctgcggc ggctgttggt caagccgaac tgatgaatat
      481 ctataatcaa agattcagtg tatataatca acagacggca cagatcctcg tgacaagaga
      541 cgtggtagat tatcctgaaa gtcgtaaaaa tgtgaggaat acattggaac agcttttgat
      601 tatggacacg atccctatcg tgaacgaaaa cgatactgta gcagtggatg aattagatca
      661 tctgacaaaa tttggcgata atgatcagct gtcagccatc atggcaaaac ttgtcgcggc
      721 agaccttttg atcgtccttt ctgatatcga cgggttttat tcagataatc cgactacaaa
      781 tcccgaggct cagatgtatc gctatatcga taaaatcgat gaaaagattc tggcacaagc
      841 aggtggtgct ggtagcacat ttggaacagg cggtatgcag agtaaattaa aagccgcttc
      901 taggatattt gaagcaaaca gcgcaatgat tttagcaaat ggaaaaaatc cggcaattat
      961 ttttgatatt cttgcaggaa aagaagtagg tactttattt aaggaggact tgaaatgact
     1021 gacttgatgc aattaggaca acaggcaaaa gatagcgcgc aacaactagc acttatgcct
     1081 acaaaccgca aaaatgagct acttgttcaa atggcacaaa ccatcaaaaa gaatcaacaa
     1141 gcgatcattg aagcaaatca taaagactta gaaaaagcag tcgaaaacaa tatcagtgaa
     1201 acgatgcaag accgcttgca gctgacacct gagcgaatca atgccatggc tacagagatc
     1261 gaaaaaattg cttcgttaga cgatcctatt ggaaaagtag atgagatgtg gacgaacacc
     1321 gacggattga gaatcggcaa aaagcgcgtg ccactaggcg tgatcggcat catttacgaa
     1381 tctcgtccaa atgtcacgac agatgcagct agtctagcat tcaaatcagg gaatgccgtt
     1441 atccttcgcg gtggcaaaga agcattcttc tcgaatcaat tattagtcca attattgcag
     1501 caagtactgg tcagtgctgg cgaatctcct tatgccatcc agtttgtcga tgatacttct
     1561 catgaaactg caggacagtt gatgcgattg acagaatact tagatgtgct gattcctcga
     1621 ggcggagcaa aattaatcca acgagtcaaa gaacaggcaa cggtacctat cattgaaaca
     1681 ggtacaggaa ataatcacgt atatatcgat aaagaagcac agttatctat ggcagtgaac
     1741 atcatcgtca atgcaaaagc ttcccgtcca tctgtctgta acgcggcaga aacattgctg
     1801 atccattctg agatcgcacc ttttttcttg ccagctattg aaaaagaact ggtagaacac
     1861 ggggtctctt tacgtgcgga tgctcgtgcg ttagaatatc tagagacggc tgctttagca
     1921 gaagacacag attgggatac tgaatatcta gattatatcc ttgctgtcaa agtggtcgat
     1981 tctttggatg aagcaattgc acatatcaat cggcataata ctaaacattc agaaacgatc
     2041 gtgacagata gttatgcggc tagtcaacgt ttcttaaatg aagtggacgc ggcggctgtc
     2101 tatgtcaatg cctccactcg ttttacagac ggatcggtat ttggttttgg tgcagagatt
     2161 ggtatctcta ctcaaaagtt gcatgcccgt ggtccaatgg ggttaaatga attaacttcc
     2221 acaaaatata tcatttatgg cgatggacaa atccgcgaat aatgtttcgt gtgaaacatt
     2281 attcccgcct tttgcctttt ttctgtaaag gttctatcca actagaaagg tgtcaatatg
     2341 tttgaaattt taatgatttt ttttatttac cttatttctc tgaatatcgc tgcttttctg
     2401 ggagtcggta ttttatccct tttctttcaa ttcaaaaaac gaagcatagg gagtcaacgg
     2461 gaaaaatggt cgcagtattt tgacaaaatc gggcaaaaag ggctggttac acgcttgcac
     2521 attagttaca tggttgcatt atgcttatta gcgacaatca attactattc ttttttcgat
     2581 cattcaatcg cttatacgat tacgctactg attgctggga tttttcactt atcttataaa
     2641 tatcagctga ataaaaacca cttgaatcgg actttccgct aaaaaatatc cgtacgataa
     2701 gtagagtgcc ttgaagatcg gcaaaaaact gccggacttt ttagaggctg tgacaaagat
     2761 tttgtcacag cctctttttc catataaacg gcgttcgcct accagctgcc tggtaaatct
     2821 gtttcctctt cgttaagaag cgaaaatccg tcaaatgttt cgccatcata ataacgaagc
     2881 agctcatcca tggacaagtt catcgttttt tctttttctt cttccgctga ttcagccagt
     2941 agctgttccc gatacacctg atacatacca gctatttttt gctgcatcgc ttttctagtt
     3001 tcaccttccg cattgattat tggcaattct ttgatatagc cacgataaat caaccgatca
     3061 tctgaaaatt caatgggtaa ttcaacgagt gtcaacccga cttcctgaaa atattcttcc
     3121 agcatctatt atccccccat tctttttctt aaatgaattt tagcttacct actgaaaatt
     3181 ttccagtttc attattttga gaaaaaaagg gaatgtgaca aaaatcgtgt cacatcccct
     3241 ttttccgaat aaatggtgtt cttctgccaa ctcctcaatc ataagtcaca atattcaaca
     3301 aacatgagaa actgtttttt gaaattgttc cttgtgattc agagttaaac gacagtctca
     3361 caacctcttg gtaaacggcg ttcaatcagc tgaccctcgg tattagctca aaaaacggta
     3421 aaatatgaga agctattttt ccgttttgtt tctctaatac ttaggataaa acgctgattt
     3481 tacaacctct gttaaacggt gttcaatcag ctgtccttcg gtattagctc aaaaaacggc
     3541 aaaatatgag gaactatttt tccgtttgtt tctctaatac tcaggacaaa acgctgattt
     3601 tacaacctcc tgataaacgg tgttcaaaag cttgcatctg cggtaataag cccaaccaaa
     3661 cgaaaaatat gagaagctat ttttgtttgg ctgttcttat gacttgatgc aggacagctt
     3721 tttcacaacc tctgatttct tattcttctt catttgtagc aaaataatta cggtgataaa
     3781 tgatacaaca tacactgata agaacaatgg cacctgcaaa ataaaacgca tagctttcac
     3841 caatatgttc accaatcaca cctgcaataa atggtgctaa agctccaccg aaaaagcgga
     3901 caaaactata gctggacgaa gcaacgtttc gttgcagacc tggtatttcc atagcaatcg
     3961 tcgtcaacag tgtattgata attccttgga aaaatcctgc taacacaatg ctgatcggta
     4021 caaggactgg catagaagtt ccagctccta ataacagcaa acaaataatg aataagacaa
     4081 atgctgctaa aattgtccga taagtcgtaa acttccgctc aagagccggt gcaacgaaaa
     4141 tcgaagcaat agccagaagc acaccccagc caaaaaatac aaaaccgact tctaattcag
     4201 aatagccaat caataaaaat ggcgcatacg caagtaaagt aaagaatccg aaattatata
     4261 acaatgcgat tagtccaact gaacgaagtt tatgattgct taacgctttg acaccttccc
     4321 aaaggcctac ttttctcttt ggtttctcag tttcaggtaa aagtaccgct agggctataa
     4381 aaccgcaaaa catcaaaaat gctaccccaa aaaatggata acgccatgaa ccactgccca
     4441 agaccccacc gactagaggg ccaacagcca ttccgcagcc aagtgctgct tcatacatca
     4501 tgattgcttt ttctgtgtta ccaactaaaa tactgacgat cgttgctaaa gcagtagaga
     4561 caaataaagc attcccgaca ccccagccgg cacgtaaccc aatcagcatt ccgatattcc
     4621 cagataatcc gccaagacca gcgaatacaa cgatgataaa caatcctgtc atcaatgttt
     4681 ttttcaaacc gatccgacta gataagaaac ctgtaaatag catcaccaca ccagtgacta
     4741 acatgtaact agtaaataac agggtcgttt cagctggcgt agcgtttaac tgtgcagcaa
     4801 tcgtttttaa gattgggtct actagaccca ctcccataaa agcgatcata caggtagctg
     4861 ctacaactag cgctgaactt ttcccctttg tttcttcatt tgtttgttct tgtatatcta
     4921 tttgattctc caatatttcc atccctttct ctctattagc atcatacatg atttatttta
     4981 catgtcaata tgcacatgta aaacgtggaa actttactgt gatataataa agaaaataag
     5041 acgagaggta ggatttttat gaatacttta gcctatatat tattatgcgt gcttttatcc
     5101 aaaccacgtt ctgggtatga attgaagcag ctgatcacaa ttttttggga agcccatcac
     5161 agtcagatct atacaacgct tgccaagtta gaccagcagg gttatgtgac cgttttggac
     5221 aaagacgagc actctcaaaa aaagatctac cacttgactg atgaaggacg tgctcttgta
     5281 gaggaatgga tcaaagagga aactcccgct cctacgcaaa aagatgaatt tctagcaaaa
     5341 atctatgctt tttcgacgct cgataaaaca acagctactg gactgctatt cactagagaa
     5401 caacagctga acaaaatcat gcaaaaaaat caaaaaaaat tgaatgacct ctcgctagac
     5461 aagaaacaag aatttggacg ttatgttgtg atccagcgca gaattatgct ttgtcagcag
     5521 gaactccaat ggtgtcagca agtaagagaa caaatgcagc agttttttga gtaagggata
     5581 aacagaacct ttctagaaat atctattgaa gagcaaatta tcttcaataa aagagcaata
     5641 cagttggaaa agaaaaagcg atccgaacga caggccaaaa cctatcgttc ggatcactat
     5701 ttttctagaa ctgcattcaa gagactatga caaaaagcat gccaaggcct tttttcaaat
     5761 aacagtgttc catcattcat tactttgaat tgcttttagc acacttcttg aaagcgggcc
     5821 aacgatgatc aactgcaacg gtaaagcggc aatcacattc attttccaag cattcatata
     5881 agcagagaat aattgatcag gtattccttg ttccatgatc acaccgaata aagacataca
     5941 tgtcaccatt cctaaaacca tcaagcatga aatagttaag atcatttgga ccttgctttc
     6001 tggatttact ggtagtttaa aggcaatttt tttcgccagc acaccgatga tgaagacatc
     6061 caaaatgaaa gccaccacga atccaggcac tagaccaatc aacaaacttg ataaatgaag
     6121 atcttgatgc agccataaat tatacgcgct catccccaag accatcaaaa aacacatcat
     6181 tgttgtaaaa attattcctt cttttttatt tgtaggcaat ctgtaccact cctttaaatt
     6241 tgtcacgaaa atcatcgtag cacatttaaa aatttctcgt aagtactttt tttattttct
     6301 gcccttttat ttcataaact tcatcagccg tacgctcgac aaagtaagaa tcatgagaag
     6361 taaacaaaat cgttcccgga tatatttgca ttagcttctc taaagcttcg atcgttgcca
     6421 tatcaataaa attagtcggt tcatctaaca gcaacacatt acttggctta gtaaaaagca
     6481 aagcaatcgt cagacgggtc gcttctcccc cacttaatgt acataacggt ttcgtcaaag
     6541 tttcctgagc aaaccctaag tgattcagca aactacggac aagcgattct gaaaactctg
     6601 tttgtctcat gacaaaacga atgatggatt cttcagatgt catttgataa cccttttgct
     6661 gatatacttg aaagcttact ttcggagaga gaaggattcc ttctccttgt ttgcggatat
     6721 gttctaataa ggttgtctta cctgaaccat tttcaccgac aatcgcgatt tttttaccta
     6781 aagaaaactg aaaatcacca tttaccagta atgttctccc acttctttcc aattggacat
     6841 tttgtcccat gatgggatag cggctgtgga gttcaagaga ttttggtact ggaaaacgga
     6901 tttgtttcat ctgctgcggc ttggttgttt ctcctatttt ttggagtctt ctctctaatg
     6961 ttttcgcatt cttttggatg gctttttgta cactgtcttt ttgtttagag gaagacaacc
     7021 gatccagtct gatttgttgc tttttctttt tactggacac tttttccaac ttttccgctt
     7081 gttttttctt ttcttggatc gatttttcca atcgtttttt ctctttcatg atcgactctg
     7141 cttctcgtag ctgagtcttt ttctccaatt ccttttgagt gagataggca ctataattcc
     7201 ccgaaaactc tcggatttct ccgtctttta cttcccagat tttcgatgct agctcatcta
     7261 gaaaatagcg atcatgacta acaaaaacca gcgtaccata ataataacga agctcttcaa
     7321 tcagtcgatc aatacttttt ctatctagat gggttgttgg ctcgtctaga agcatccctt
     7381 gttcataaga agaaagaaga cgtatcaact cgatctttcg ttcttcccct ccgctccatt
     7441 tccgctctga agtttcttcc agtcttaact ggaaatgact ggctaattcc aaatttaggt
     7501 cctttgcttc agcgagatag gttaattgag gcaggtagtt gaaggtgatc tctgtttgga
     7561 ttttcccatg atcgggaaaa agttcaccgg ctattagttt gagcaaagtc gatttaccga
     7621 caccattttc tcctatgatc cctatacgat cttgctgata gacacgaaga gaatcaatag
     7681 atagttctag ctggttgcca aagctgactt gtagatttgt tatatttact gctaaatttt
     7741 ccatatgttt tacactccta tttcatgtaa aacaacaatt atcgatacta aaaaagagca
     7801 gaaaaatctg tttgcaaaaa aactgcatca catcttttcc tactctgaac gaaataacta
     7861 tgactaaatc accaaatctg tcatagcttt cacctattct actgtcgttc gaaaaaatgg
     7921 acatactcca tccatgaaat tgttgtttat acatgtcttt tgaatttatt tagttgttat
     7981 tcaaaagttc gaaacgtaat ttcatcgatg cagtcatttt tccgacctcc ttttttatta
     8041 ggttaccaca cacgattcaa aaaaagcaat agctactgaa tagtaactga aaacctttta
     8101 ttcgaacata gtgatctttt ctggtgctaa acgaacagac tcgtaacctt cttctaccgc
     8161 ttttcctatt gataaaataa taactggaac ataacggtct ttatccaaac caaatgcctc
     8221 tgccaactga tctgcttcga atccaccaat tggatttgtt tcatagccat gatcacgcgc
     8281 aactaacatg aattgcatag ccgctaagct agaatcgact ttgactacat cgttcatttc
     8341 ttctcttgaa aaactcttgt aataaggaat gatcgcagct aattgttgat ctctgacttc
     8401 ttttggcatc ttccctgatt cgtaagcttg gttgtagatt tcttcgccat attcgtaaca
     8461 ttgcatatcg ccaaaaatca tgaccattgc agaagaagta tcattttgtc tcgtattgaa
     8521 acggatcaaa ggacgcaaga tttcttttgc ttcctcgctt tcagcgacca caaagcgcca
     8581 tggtttcata ttgacagaag aaggtgcagt cgtcgcttct ttgatcattt ccagcatttc
     8641 ttcgtgtggg attttgtatg tttcatcata tacgcgaacg gatcttctac cagtcataat
     8701 tgttgaaaaa tcattttttt gttccattat tattaacctc tttcgtttct gttgttatat
     8761 tgcaaagttg ggtattcaat ttatctaaaa gtgttagaaa ttgtttcatt tctacatcgc
     8821 tgaaagccgg ggatagcacg gaacctgtat ctttatggtc catttcacaa tgcttgattt
     8881 tcttctgggc tttttctgtt agcgctacat acacttcccg gttgttctga ggatttctct
     8941 gacgcgaaac atagccattt gcttccaata ccttcagatg acgagtaact gctccttgat
     9001 caatctgcaa cttttcttgc aaactgcttt gtagcaatgg attttcttct ttcagtctca
     9061 tcatgatctc gtatctagta agacttatac cgatattttc ttcaaagatc tggacgattt
     9121 tttgatcggc taatttgatt tgatataaaa ggtgactaat ctcttctaaa gacataattt
     9181 cctcctttct aataattgac tcgtcaacga ttgacttgtc aataatagaa taaaaaaaga
     9241 aaaaagtcaa agaatcagct gtgtaataaa aaaaacgctc tcaatagaaa agtatagaga
     9301 aaagaaattt tttgtagaat gaacggaaaa aatgataaag aaagcacaac gctaaaacca
     9361 agattattga ttcttatcaa actatagaag atagctcttc tgcagtagat aattttacac
     9421 cgccaaaaat ttccgaaatc gccttttgca agaatcccgt cgaatattag aaattggatc
     9481 agtatgctta aacagtaata aaaaagttat gacaagatgt tgtcacaacc ttttttgagt
     9541 aaacggtgtt caaaaacttg catctgcggt aataagttca accaaacaaa aaacatgaaa
     9601 atctgttttt gtttggctgt tcttactact tgatgcaggg cagctttttc actacctctt
     9661 tttaataacc ataaaatcct attccttcat atctccagcc catcggtgtt agccaatctc
     9721 tttccttagc actcaaggta tagtgatggg taccagtttt ttcatttgga ttaaatagtc
     9781 gataaattgg cttggaacca ccagaataaa aacttagacc ttcataacgc caaccgattt
     9841 ttgttaaaga gttgatctca gattgtgcca ttgtgtaatg atggtctcca ctgtaaggat
     9901 tgtataaacg gtagacaggt tgtccgctgt ttggtgcttg ccaagcaatc ccttcatatt
     9961 cccagcctac agttggcaga taattttttt ctccggcatt caatgtatat aaatgttctc
    10021 ctgtatgacg gttatacaga cgatacatcg gagaagttga agttggtgct gtatcatact
    10081 gtgtcagatt ataggtttcg attacattgt tcaatgtaga accataatta ggcgcagtgg
    10141 cataacgacc tgttagccaa gccgtagcat ctttgtaaga gttcgtattg cttttccatg
    10201 caccggaata gtagtaaacg cctggctgaa aagaagtcgt cttcaatacc gttacgttat
    10261 cttgcaatga ttctttgtac gaaggatatt ttctaaaagc ggcattcacc gtaatccatt
    10321 gcccattcac atattccgaa gtaggcatcg taacagattg gccattatag cttcctttaa
    10381 tcccaaatag attgtaatta ggggcagaag ccaaagtact gttcccccag ccactttcaa
    10441 cgatggcttg agcaatcatg actgatgcat ataagtcatt ggcacttgcc aaactttgtg
    10501 cagttgaggc aatactatca atgaacgctt gttgagaatt agcagatgag cgagcataaa
    10561 aagcatagcc agtatagttt tcgaattcag acaaatctgc ttgatgggta tgtgtcaatg
    10621 tttgcccatc tgtcaattgg ttcgtgattt cttctgcatt ctctggattg ttctgagctt
    10681 ctgctgatgt actgtcttcg gtttgtgttt gttctgttgt ttcagttgtt ggttcttcgg
    10741 ttgaaattgt attttctgag acagtagctg actgcaaagt actttctgta tcgttttcaa
    10801 ttcctgtttc tgaagaactc gatgtctgag ttgcgacagt ttctgtcgat tcttcagcta
    10861 gcactgttgt gttggcaact gctagatttc ctaaaagaat aacgctaaat aataaattct
    10921 ttgctttcat cttttttctc ctttgaatta tgaaactttt cctaaataac agtgtaacta
    10981 aaaaagtaaa agcaagtcaa tgtccatatt taaataacat ttgtttcttt ttaataaatt
    11041 tgctttttct gcataaaaag acgtaaatga agaatattct tctccattca cgccttaaat
    11101 tgatggtcgt ttgaataact atttaacaag taattctctc tggatattat ccgttatgga
    11161 ttatacttcc tgtgtcgtcg gacggataat catgttgctg acagacatcc ggtctggcgt
    11221 ttctatcgca aatgctacag cagaagctat atcttcagat gttaatcccc attctttttg
    11281 cgcttcatga agttcaagag cagccttttt gtcgctgatg gtttgatata attcagtttg
    11341 aacagctcct ggagagatga tcgtagattt gatgttattt tgccgttgct cttgacgtaa
    11401 tccttccatg attgcacgga cagcaaattt tgttccgcaa taaacggcgg aatcaggata
    11461 aacaacatgt cccgccacag aatcagttga aatgatatgc ccagattttt gtttttccat
    11521 gattggaagt acggcggaaa ttccatttaa cacacccatg atgttgatat caagcatatt
    11581 ttgccattca tcacggtgac cttcaactaa tggagcggtt ggcatgattc ctgcattatt
    11641 gtacaataca tcgattcgac cgaacttttc catcgctaaa tcgataactg cttggacttg
    11701 tgcaaaatct cttacatctg ctgtttgaat atatagctca gcttctggta aagattcttt
    11761 tattgctttt aggcgatctt ctcggcgtgc agctataact agtttagccc ctttttctgc
    11821 taatagcttc gttgttgctt caccgattcc gcttgaagcg cccatgatga caatcacttt
    11881 ttctgataaa tcattcattc tattctcctc ctgttttgaa aaatctcttg cttatactca
    11941 ctatctctta tttcatctta ctgttcaaat aatccgttcg acaggtttga cgattttggc
    12001 agggattcct gcaacgatgg tattgtctgg gacatctttc gtaacagttg cattcgctgc
    12061 aacaatggca ttctcgccaa tcgttacgcc tggcagaata gttgctcctg ctccgatcca
    12121 agcatttttc ttgatgtgga ttggctttac tgacaagcct cttcgttctt ttggatcggt
    12181 tagatggttc accgtgatga ggttgacacg aggaccaatc aatactgaat cttctaaaca
    12241 gatgccacct aagtcaacga acatcacttg acgattgata aagacatttt tccctatact
    12301 aatatgtttg ccgaaatctg tataaaaagg cagcagaaca gtcaccgtat catctacttt
    12361 gtcactaatg atattttcta gccgtttgcg gatatctgct ggttcatggt acccagtatt
    12421 cagcgctgct aaaggctctt cgttttccgc ttggatctga tggatcactt caaagagcgg
    12481 atccgttact cgaatctctt tattgacgat ttgtttttcg atgaggcttg tcattttgct
    12541 ccctcctttt atccttactt tataacggac ggcttatgat gtctaatact tataaaacat
    12601 acttaactat tccttttaac tatacttagt ggtatgcttt tttaaaaaca ggagggaaaa
    12661 aatggatatt cgtatactga cgtatttttt agcagtagct agagaaaaaa atatcagccg
    12721 agcagcaaaa tctctgcata tcacgcaacc tactctctca aaacaactga aagatttaga
    12781 agaagaactt ggtgtgacac ttttcactcg aggctcccga gagatacagt tgacggattc
    12841 tggtcgatat ctttattcaa aaggaaaaga aatcttgtcg ttggtagaaa aaacggcgaa
    12901 caatttaaca aatgacgcaa tcatctctgg agaaatctac attggcggag gcgaaactaa
    12961 agcaatctct ttcatttctg atagccttca ttcgttgatc aaggcgcatc ctgatatcca
    13021 gtttcattta tatagcggga atgcagatga tatcatagac aaactggata gcggattact
    13081 tgattttgga ctcgtaatcg aaccgacaaa caaacaaaaa taccagtcat ttcgactgcc
    13141 agcccaagat cgttggggac ttttgataca tcggaatcat cctttagcaa agcaaacagt
    13201 catccatccg caggaactga aaactgttcc tttgatcatt tcccggcaaa cgtcagtgga
    13261 cagtcaacta gctgaatggc taggtttcag catagatcag ttatcgatcg tcggaacata
    13321 taacttattg tacaatgctt ctttgatggt cgataacggg acttttggtg cattagctct
    13381 agatgggatc atcaatactt atgggacgga aaaagtattc atcccactcg atccgccatt
    13441 acaagcttca ctgaatctca tttggaaaaa agaccagcct ctttctcctg ctgctcgtaa
    13501 atttttagat gtcctaacgg agaaatacag ttaagtagag tttttttcct tcgctttcag
    13561 ctttttaaca acgaataagt taagcaaaag atccaatgat taaataacat aagtttctta
    13621 atttgttcct tccttttatt tctgataatt ccagtaaatt actataatta taaaaaaaga
    13681 attgacaaaa cataactgtc tatataaaat tgattacgtt aacaataatt cgtttcatgt
    13741 gactagatca tactaggcat gaaaaatctc tgaggaacat ggtttcccta ggaggttttt
    13801 cgtgtctatt tttgtttggc cgcaatcaac tggtctagca aacgtgaaaa ccaaatcttc
    13861 aaaaagggtg cgcgcatgaa aatcaaaaag atctttaatc aaaatgcagt attggtagat
    13921 gacggtggac aggaaaaagt agctattgga aaagggattg gatttgacag aaaaagaaat
    13981 gatttgattt ttgatcgtga tgtcgaacgg atatttgtca tggaaccaga aggtcaaatc
    14041 aagttgcaaa atttacttaa tcagattgat gaacgctttt tatttgcagc agaaacgatc
    14101 attgatcatg cggaaactgt tttgatggaa aagttgaatg aacatgtatt gatcgctttg
    14161 accgaccaca ttgctttttc tgcggagaac attaataacg gtatcgtcat ccgcaacaaa
    14221 cttttaagag aaatcgaagt gctttacagt gatgaattca gtattgctca atgggcagta
    14281 gagtatctga caaaagagct tgggattcca tatacttatg acgaagcagg atatatcgca
    14341 atccatattc acagcggacg aagcggtcgg aacaataacc atcgcagtat ccgtgaagtg
    14401 acgattgtat ctgacatcat ccatttagtg gaatcagaat tggaaacaga tatccattca
    14461 gaaccatttt cactgaatta ttcaagactg gtgaatcatt tacgactgct tctacaacga
    14521 acccatgcgc aacaatatgc tgttttagac acggaaatcg tagaaatggt caaacgaaaa
    14581 tacccagaaa gctataagat ttctaaaaaa atccgtgtgt tgctgaccaa agaataccag
    14641 ctcgcgatca cgaaagaaga actgggttac ttggccatcc atatcgagcg tttaagaagc
    14701 gcaatcgtac aaacaaatgt taacaatcat gaggaggaaa aaaattgaaa gcatatctac
    14761 aacgaatggg acgttccctt caacttccag ttgcggtctt acctgctgct gctttactag
    14821 tagggatcgg aaactggtgg gcatcttata gtaacgacat tgtcgctcat tttttacaag
    14881 ctggcggtaa cgcagtttta ggtcaattac ctttgctgtt tgccgttggg ttagcactag
    14941 ggatgtcagt ggacaaatca ggtgctgctg ccttggcagg tttggtcgca tttgaagttc
    15001 cagtaaatgt tttaaaaact gattcagtag ctactttatt gaatatcaaa ccagaatcag
    15061 ttgatccatc ttttgctcag atcagtaacg tatttattgg tattattgcc ggattgattg
    15121 cggcagctct ttataatcgt ttccacgaag caaaattacc gatggcttta tctttcttta
    15181 gcggcaagcg tctagtgcca atcttggctg cctttgtcat gttgctgatc agtgcagtgc
    15241 tactgctcgt atggcctccg gtttactctg ctttagtttc ttttgctaaa ttcattttga
    15301 gtttaggctg gggtggtgca ggtctttatg gcttcttcaa ccgtttactg atccctacag
    15361 gattgcatca agcaatgaac tccgtgttct ggtttgacgt agcaggaatc aatgatattg
    15421 gtaaattttt ggcttctgaa ggaacaaaag gcgtaacagg aatgtatcaa gctggatttt
    15481 tcccaatcat gatgttcggg cttccagcag gagcatatgc tatttacaga aatgcacgtc
    15541 cagaaaacaa agcaaaaaca gcttccttga tgttagcagc agcttttgct tcattcttta
    15601 ctggtgtaac agaaccactt gaattctcat ttatgttcgt tgcttggcca ttatatgtct
    15661 tgcatgcaat tttcactggg atttctttag cagtgagtgc attcttccat tggacagcag
    15721 gatttgcctt tagtgccgga tttgtcgatt acttcctatc tttgaaaaat ccgattgcga
    15781 atcagccatt gatgttgatc gtccaaggat tagtaacagc agtgatttac tactttggct
    15841 ttaactttgc tatcaaaaaa ttccatctga tgactcctgg ccgcgaggaa gcagatcttt
    15901 cagatgacga tactgcaacg actaattcag acaataaata tgcggcacaa gcaagcaaaa
    15961 tctacgctgc attaggcgga gccgacaatg taacttcgat cgataactgt actacacgcc
    16021 ttcgtttgca agtcaaagat acaggcctga tcgatcaaaa taaaatcaaa gccactggcg
    16081 tacctggtat gaagatcatc gacggaaaaa atgcgcaagt catcgtaggt acagaagtac
    16141 aattcgttgc agatgagatg gcaaaactac atggtggtgc tgcaacacga cctgcacaaa
    16201 caaacaccgt ggttaaaaca gaaacatttg ccggtggaac gatcgaacaa gatatttacg
    16261 ctatcgcaaa tgggaaactg attccaatca ctgaagtttc agatgatgta ttcgcggaaa
    16321 aaatgatggg tgacggctat gctgtattac cagaaaatgg agaaatcttc tctccaatcg
    16381 ctggtacgat cacaaacatt ttcccaacga aacatgctgt cggaatccaa acagatgctg
    16441 gtatcgaagt cttgcttcat atgggcatca acactgttga cttaaaaggc gaaccattca
    16501 ctttatatgt aaaagaaggt caaaaagtcg caagaggtca attgattgct ttagttgatc
    16561 ttgccgctat tcaatctgca ggcaaaaaca cggatatggt cgttgtattc acaaatggcg
    16621 acaaagtcca aagcttagaa atcgaacccg cacgtgatgt aaaagcaaat gataaaatcg
    16681 gctctgtttc caacaaagcc tgagccatcg tcttccccag acttttttat cgataaacaa
    16741 acaggagctg agacaaaaat cttgtctcag ctcctttttc cgaataaaaa cggcgttctc
    16801 ctgccaactc cgcggtaata agtccagcca aacgtaacat atgaagagct attttttatt
    16861 tgactcttct tattacttga tgcagaacag cttttttaca acctctgata aacggtgttc
    16921 aaaaaccagt ttatcggtat gaagtcaaat ttatgcaaaa atgtggaaag ccattttcac
    16981 aaaatttttc ttcatactca aaactaatcg gctttttcac aacctcttta tacattattc
    17041 ctgatccaat atttctttta atgctgcttc aagagaagtt aatggttttc ccaatacttt
    17101 ttctaaatca tcagaggaaa tagctaactg atccttttta atatcatgtt ggatcgctaa
    17161 aaacatgtca gctgcttctt gagggaatcc ggcttctttt agattttcga caaacgctgc
    17221 atcacttgct tcaataattt ctaacttttt acctgtcgca cgctctaatg ccttggctaa
    17281 ttcttcatag tcagttagat tgccggataa ttctaagatt tctggagagt cactttctac
    17341 tagtactttt gctgcagctt ctgcatattc acgtttcaat gcccaacctg tttttccatt
    17401 tcctgcagca taaacgaatt gaccagtttt taaagcctgc ccaatgatag gtaattcatt
    17461 ctctacatac caattattcc gtaaaaatgt atgggaaata cctgaatcct taatcatttt
    17521 ttcagtgaat tggtgatctg gcgctaatac actgatcgag tgatcggcat ctgcaaaact
    17581 tgtataagcg atataagata ccccagctgc ttgtgctgcc ttcactacat tcttatgttc
    17641 ggcttgacga tttcctggaa cgccagagac aaaaagcaat cgatctattc ctttcaacgc
    17701 ttctttcatt gagtctaaat catcataatc accaatacgt atattaaatc cagcttcttt
    17761 cagtgcttct cctttttctt cactacgtac tagtacatag atttcatttt gtggaaccat
    17821 cttttttaag aattccagcg cataaccacc aaaacctcca gttgctcctg ttactaaata
    17881 atgcatattt gccactccct attcttttta tttgttaaga tttacagctg tacatttata
    17941 aattacacct ttatcataaa gagtgtggta agataagtca agcaaaaaaa atgaaaggat
    18001 gacaactgat gaagtattct ctgcaattta gtgatgcaat ccatgtactt gcctatattg
    18061 aaatgtttca agatacccga tcactttcta gtgagatgat tgccagtagt atcgaaacaa
    18121 atgcagcaaa tgtacgtaaa atcatgagtc agctcaaaaa atccggtttg atctttacaa
    18181 aaaccggaaa accgcagcct tcccttgcca aaagtccaga tcagatttct ttactagatg
    18241 tctatcgcag catcgaaggt aatacacagc ttatccaagt cgatccaaaa acaaatccaa
    18301 attgcgtcgt tggtgcgaat atccaagaag ctttagaaga aagctacgct cggctgcaga
    18361 aaaaggcaga agaagaaatg gctaagatca cacttgatag tctgatacat aaaatagccg
    18421 ttttggaaaa agaaaaaaga ccagaaaaca caggcctcgt agagagattt ttataattct
    18481 ctctactgtg cctgcatttt tctgatcgga atcgtctaca taaattcttt tattctccgg
    18541 gggacaaaag ccttgtcatg cccctttttc ctctctaatg ctcaggtcaa agcgctgaag
    18601 tcatgacgtc ttgataaacg gtgttcaagt agctgaccct cggcattagt tctgaaaaat
    18661 gcaaaatatg gaaagctatt tcccattttt cctctctaat gctcaggtca aagcgctact
    18721 ttcacgacct ctatattatc atggtttatt gactaccggt atccagattt ctcccatata
    18781 tttcccgttg gtaactccca tttcgactac agcatttgga cccccaacat aggcgtaatc
    18841 ttctacttct cttaaaacat gcccaaaggc cgtattcgtc aaatcatttc ttaattcttc
    18901 aggcgattct gctaaagcga ttacaacaag atacgttcct tttgggaatg ggatgattcg
    18961 ggtagtgttt ggaacatcct gactcgtttg aacaccgaca tagtacatca ttttcccgtt
    19021 atagggttcg ttgactgtaa agaaataatg attttcagca gcttgtttca atgcatctat
    19081 tgttccatta ccgataactt tttgctcaaa tgcttgtttc tctgcagcca aaccgacaaa
    19141 atccgtattg ctactcttca attccacacc aatacccgtc accgtaaaat ctggtttttc
    19201 ttcgatccta tactttgcca tttctcccac cctttctatt atattaagtt catcttacat
    19261 aaaattaaag ggaaatgaca cgattacgct cttttttcta gggatatttt tattttttaa
    19321 ctattttttt gctttcactg caatccaaat ctcactgtaa acattactga aatcctctcc
    19381 ccattttgta aaagagatct cgggagcttc gactaactca taatctgaag aaggaagcca
    19441 ttctgcatag attttccccc aagtatcttg taaagtttgg ggaaatggcc ctttattagg
    19501 aaaaatggcc caagtgtgtt cttctatagc aagcatttct aaatcagcgt acggattttc
    19561 ttttgtcgta gcaaagccaa tcatgtgcat caaactgccc ttttcttcca agcgggctcc
    19621 atcaaatcca taagaaacgt tgattacttg atttggatat aaatctccta acttatgcat
    19681 ctcttccctt tgagtctccg tgatcgtctg cgctaacttt tgtatttctt gattgactcc
    19741 ttcaaatttg acaggaactt ttttcgccac acctgccaca taaaactgtt ctttcttttc
    19801 gatacgaaat tccatcgatt ttcctcctct gacatcaata aaaaatgtca agcgtggaaa
    19861 agatttttgt atgccgtatc tgctgatttc tgaaggcaga tatcctgacc aatcacgaaa
    19921 agctcttgaa aaaccttcga ctgtttcata tccatatcta aacgccgttt ctgtcactct
    19981 tgatccatct aggagatcgc gattagccaa agccaatcta cggtttttga tatagtccat
    20041 tagcgacatc cctgcaataa acgtaaagat gcgttttaat tgatattcag agattcctgt
    20101 attttcggct attattttat aggaaagtcc ttctgtcaaa tgttcttcga tgtaatcgat
    20161 caattggttc agatctttaa gcatatttat cttcctcctt gcttgccttt ttatcatatt
    20221 atcaaagaaa gtcaattact tgatgaatca ggaaccaatt tagtcagatg tagaaaatgt
    20281 tgtatggatc taaagaaaat tctcaagcag cgtttcgtaa cggataattg gtattatctg
    20341 cctatctatg ttttaccttt agaaaaataa attttgggga agacacattc taagtaaaca
    20401 aagcggtaaa aatatctttt attcccttag ttaatccgct tactacctac tgtacaaagc
    20461 aaattgttgt tcaaactgct gatcagaacg ctgcttggat ttttctttgc gatacatcat
    20521 acctctttta tcaattggaa caattattta tttctaacaa aatcacttca tttttgtcag
    20581 ataaataaaa aacaaaaaaa gttccatctt taaaacacgc tattctttta ctttttctca
    20641 cattctctaa gaaaagaaaa ggagaatgaa tttttgacaa ttcgagcaaa agtgattatc
    20701 aaatatgtaa aatcagctac ttttttctta aacgtttctt tatactaaat ataaataagt
    20761 gtttcatgaa aggagaacta gatgaataat tggcttgagt attttcctga aaacgttttg
    20821 gaacgcggtt acagctatca tctgcacggt tttgtccgtc atttgaacta tacaagcaag
    20881 tacttgtccg caacagtttc tggcacggaa gattataagg tagtgatcac ttgggatgaa
    20941 aagaccaaca tgacttgtga ttgtctatat gccatagaag gaaaaaaatg caaacacatg
    21001 gctgctgtct tattcgctta cgaagaacgt ccaataaaaa aatccaacta ctcactttcc
    21061 gaactctcgt cccttgtttc ctccgctagt tcctctcttg tacgggagct tttaacagag
    21121 attcttatag aacatccgca atttatcgaa cgcttcaaag ttaagatgcc atttcatgca
    21181 ataaattatt cagataaatt aacaactatc atccataaat acgatcatat tatcaagaaa
    21241 aacaaaaaca ggaaaacagc gaagttcatc atggagatgc gaaagttcat ccaagaagca
    21301 gttgaatcgc tcattcagca aaatgcctat cttcccgcat tcgaattgat caatgaagtg
    21361 attgctactc tcgaaacatt ctattgggag cctgaggatg aacgaaccct tcttctgata
    21421 gaggactgtt attatttatg gaaagaatta ttagcagaag cacctcatgc agaaaaaagg
    21481 caaatgttct cttggttcgt ctgccaagtc gatcatactg acgcctctta ttcaaaacgc
    21541 tactccataa aaatcctgaa agaagacttt cgggaaaaag aattttctaa ccaaaagaaa
    21601 aaaatagata aaaaaactaa agaaacggta aagaaagacg atttcaatga aaaatagcaa
    21661 gtaaacgata acaaccatcc taaatccaca agaaatacag cagaccttgc tttaaaaaca
    21721 cgaatcatgc aaaggatgaa gtaaagaaga cttaacgcgt acccaatatt agtcatttga
    21781 ctattaggta cgcgttttgt tttataagtc atgacaaatt tccttcgttg ctgggtagat
    21841 tttccggcat tgttgataga ttttatgata cttttctaca ttttgtaaga gaggttccac
    21901 tgcatctgta tattggataa aattctgaca acaactttca ggtgtgtcga accactctaa
    21961 tctttaaaga taaatattaa aataacgatt aataatatta acagtcttta tttttcacca
    22021 ccaaaaacct atctttgcat atactaaata gacgtatata cacagatagg tttgtcttgt
    22081 gaaaaataat gattatcctt accaaaaaat gtttgttttt ctacatgttc gtacttatca
    22141 aaaaatatga tccttattga aattactggc tatttatatt ccaacgactt cttgtgttaa
    22201 tttttgttat ctcatagtaa attatgtttc attttcactt aatttagttg tcacgtgttc
    22261 gtcaattcgt aaaaacggta aatatataaa cacacttgcg gctataatta atatttgtaa
    22321 aacagctgct cgccagtctc cggctgttgc taaaaatccc gatataactg gtggcgtagt
    22381 ccaaggaatt tgcactacta catgattaat taatcccaca gcagttgcaa aatatgctac
    22441 tgtcaaagaa aaaatcggtg caagcacaaa gggaataatc agactgatat taaatacaat
    22501 aggcaatcca aaaataatag gttcgcttat attgaatata gcgggagtta ccgataattt
    22561 agcaaagtcc ttataatctt ttctacgact gaagataaat attgcaatca ataaagcaat
    22621 cgtatttccc gatccaccca ttaccgcaaa ggtatcttta aaggccatat tgataatatg
    22681 tggaatttgc tctttgtttg cataagctgc catattttct tgcatattct gaatcaaaaa
    22741 cggatctaac aatgaacctg atattactgc ttgatggata ccaaatccaa aaaatagatt
    22801 agcaatagat gtaattaaca aaaatcctgg taaaccagtt gtaattttac ttaatggctc
    22861 tgtaactatc gtggtaatta gcttatttat atccatatta aacaattgaa tgattataaa
    22921 tgacaataaa gcaaacgagg taatcgtaat aatgattggg attaatacat taaaagactt
    22981 taaaacagcg ggaggaatat ttccggatag ctgaatctgt agtttcttat tattagaaag
    23041 tttaataaat aattctgtag ccgctaatcc aacaaatata cctacaaaca ttcctgaagc
    23101 tcctgtatag gatataggta tcacacccgt cacttcaaca gctttatccg cattttcagg
    23161 agtaaacatc atctgcatag gtgttaatac aacaaatgtc gaaatagcaa ctaataccgc
    23221 tgcaatatga tttgtataat ttctgcttgc acacatatga taagatactg ctgctacaac
    23281 taataatgta gttatgctta atgtaccatt ggcaattgaa gtaccaattt gttgtaacgt
    23341 ggtcaatgta ctagtatcga caatttcccc catgaatcct gttggttcta agatcactga
    23401 attaataagt gtcacaaatc ctgctaacat cataaatggc ataaatgtag caaacgcatc
    23461 tcgcaaagtt cttaaatgga tctgattccc caacttagtc gcaactatac caaatttttc
    23521 aaatacaatg tccttcctgc tacttttgcc catatttttt ctcctttatg cttattgtaa
    23581 tcgattactt tttccaccca aataatacat cacttatcaa aaaaagtaaa tacttttaat
    23641 taaatatata tatctttttt agtataaaaa aataagctct gaaaaaataa ttttcccgag
    23701 cttatttttc aacaaaaaca gcttcaaaaa caaagtcttg atataaatgt ctcgataccg
    23761 aatactcgaa aggtttacca gacgatagag caacaacttt gtctatctca atcataaatt
    23821 cacctggatc tatttttaat atttttgcgt caaattcatt cgcagtatct cctttgatac
    23881 gtatgtgcga agtctttatt tccagaccca gttcatttgt gatataagca tatacagatt
    23941 tctttaaatg ttttggttcc aagcctggta tgactgctaa tggcatgaat gtttgctcaa
    24001 tcgagtatgg ttgacaatca ataaaacggc ttcgtacaat attatataca tagtctttta
    24061 cactgatact taatttatca gctacttttt tcgatggaag ttcaattgag aaagtatgga
    24121 tttctgaatc tacgtgttct tcaccaacca cgctaaacaa accttcgttt ggaccaagaa
    24181 ctcgtgagtt atcaattggt gttctgacga cttcagtccc atacccactt ctacttcgca
    24241 aaactccttc ggaaacaagt aagtctacgc ctttctttac tgttaacttg cttgtatgat
    24301 aaataactgc caattcatct cctgtaggaa gtttctcacc aattttatac tctccattta
    24361 caattttttt ctttatatct aagtaaattt ccatatactt cgcaattttt ttcaatggtg
    24421 accctccaat caaaaacata tcttcatcta tactttaaca taaataaacc gataaaatcc
    24481 acatcaaaat tatacacaca ataaaaaaga tatatatatt taaacaaaac tatttacttt
    24541 aagttgtaag cggtgttatc attaagtgga aacaggaggt aaaaaaatta tgacaactat
    24601 gaaaaagcta acttttccag atgatttttg gtggggttcc gcttggtcag ctgagcaagc
    24661 agaaggaaaa ggagaaacag gaaaagcaga gactatctgg gatcgctggt ttaaagaaca
    24721 accttaccgg ttttatcaac gaatcgattc ctctattaca accgatcaca tccatcaata
    24781 taaagaagat atagaactaa tgaaaaaaac tgggcataac tcctttcgcg tttctatttc
    24841 ttgggcacga atgtttccaa atggcggtac cggaaaagta aatcccaaag ccatttcttt
    24901 ctatcgaaaa ttattttccg aaatgaataa taacggaatc aaagtatttg ccaacttata
    24961 tcattttgac atgcctgcta ctcttcaaga taaaggagga tgggaatcac gtgaagtagt
    25021 tgatgcttat gttcattacg ctgaaacttg ttttaaagaa tttggtgact tagtttgtca
    25081 ttggtttacc ttcaatgaac cacttgggcc tattttaggt acttatcttg aagattttca
    25141 ttatccaaac ctcattgact ttaaacgcgg agcgcaagca gcattcttca ctatacttgc
    25201 acacgcaaaa gcaatacaag tatttaaaga actagctctt cctagtaaaa taggcgttat
    25261 tctaaatttg agtcctactt ttcctcgtag tcaaaatcct gctgatgtga aagcagcaga
    25321 aatcgctgat ttattttata cgcggagctt tttagatcct atggttaaag ggaatttttc
    25381 taaaaagctt atcctgttat tacaagaata taatcagctt cctgaagatt atacgaaaga
    25441 agatcttgta tgtatctacg aaaataccgc tcaaattctt ggactaaact attacgagcc
    25501 acgtcgcgtc aaatctcgtt cttctatggt ggatacatct agtccatttt taccagagtg
    25561 gtttttcgaa ccacatatca tgcctggacg acgaatgaac gaataccggg gatgggaaat
    25621 ttacgaaaaa ggaatttatg atttgtgcat ggatatcaag aaccattatg gaaacatcga
    25681 agcatttatc tcggagaacg gaatgggcgt tgcggatgaa gaacgtttca tggatgatac
    25741 agggcaaata attgatgatt atcggattga gtatatcaaa gatcatcttg cttacttatg
    25801 gaaggcaata aatgaaggat gtaacattaa ggggtatcat ctttggacat ttattgattg
    25861 ctggtcatgg atcaacgcct ataaaaaccg atatgggctg gtttcactcg accttactac
    25921 tcaaaaaaga acaattaaaa aaagtggcga attttacaag caattaagtg atacaaatgg
    25981 atttagatac gatgtagact tgttagttga ataatattct aaaattccac ttgaagtgaa
    26041 cacattagaa aacaagaata atgagaaata ccaataacaa atactttttc ttcatacttc
    26101 atttatactt gtcagtataa gagactgtga caaatgtagt gatcctcaga agttaggtct
    26161 ggaaatctaa cttgagaaga tttttttaaa ctacgtccag tcttttttat ttgtttaaaa
    26221 ttgaagttga caagtcttca ttaaaaattt agaatattca caagtttgac gacaattatg
    26281 aaaatttatg tcgtgctaaa ggagttttgt tattggatga aaagttagat ataaaaactg
    26341 cgatcaaaga cacgttacct accgtttttg gttatatcgg tattggactt gcatttggta
    26401 tcgttgggaa agctgccggg tttcatccgc tggtcgtcac gttgatgtcc ctgctgatct
    26461 atgctggttc tgcccaattt atcacggtca gcatgcttgc tagccatagt ccactgctct
    26521 ccatcgttct ctcgaccttt ctagtcaatt cccgaatgat tctgatgagt atgacgattg
    26581 ctccttattt caagaaaaat cggctgcttc aaaatctgct gattggcaca ttgctgacag
    26641 atgaaagttt cgcactggga atgaataaat tgaactatac tggacaaaag ttaaactttc
    26701 gttggatgaa tacagctaat tggatttctt atttgacgtg ggtgggttct tctcttgttg
    26761 gcgcactttt agggaatttt attactgatc cgaaaaagtt tggtttggat ttcgccatcg
    26821 tcgctatgtt tatcgggtta ctttatcttc aagtcatttc tgatagaaac acctctaaac
    26881 gattacagtt gatcctgatt ggtctcactt tgattctggt atatgtcgga ctgattttta
    26941 tcccaagtaa cttagtgatt ttagttgtaa cactgattgg gtgcggattg ggggtgtgga
    27001 tcaaacatgc cttcttttga gtttacattg ctgactattt taggttgtac tttagcaact
    27061 tggctttcta ggatcctacc atttgtctta ctgaaaaaat tcgatttgcc gcaaccgttg
    27121 cttgagtatt taagttttgt cccgatcgtc attatgtctg ctttatggtt cagcagtcta
    27181 tttacccaaa atatcggaca tctgccgcag atcaatctcg aaaatgcttt ggcttcagtt
    27241 cctacacttt tagctgctat tctttcaaaa agcttattgg tgatcgtctt ggtaggaatt
    27301 ctttcccttt cgttgattcg cttattataa ataaaaaaac aagagcttat ggcaaattac
    27361 tgtcatgcgc tcttgttttt atcaaagtca aataagaaaa aaatcggcgt attcttgctt
    27421 atccgttgaa cggaccacta acaacgactt ttcctaatat atgtcctgtt tctacgtctt
    27481 tggttgcttg tttcaagttc ttcgcattca tcccatctga atagaccttg ctcaatgtac
    27541 tgcggataat cccttcattt gctaaagcag caatgtgcgc taaagcttct ccttgcgttt
    27601 cgatttcata gttatagtct gttttagcga acatatactc ccagtcgaag ctgatagatt
    27661 ggtttttcca aacacctata tctaacggct ctttgatccc tacgatcgtt cccacatgtc
    27721 caaatggtcg gacaaggtgt ttgatttgat caaagtagcg ggtaatatcg aataatacag
    27781 cgacatactc tacttgatcg attcctaatt cacgaaaact tttacttaag tcgtgatgat
    27841 aatcgattgg atagtctaca cctgtttttt tcagccattc aaaattcttc ggacttgcag
    27901 tcgcgtagac ttctaggcca gcccaatgcg ctagttgatt caaaatcgaa ccgacgcccc
    27961 cagctccgtt gatcactaag atttttttcc cgcggttggc attttcttct ggagtcagac
    28021 caaatttttc aaataacaat tcataagcgg tcaatgaggt caacggcaag gctgcggctt
    28081 cttcatctga aagatttttt ggtgcaagag cgacaatacg ttcgtcaacc agttggtatt
    28141 cttgattgct tcctgctctt gtcgttgtac ctgcgtaaaa aacgcgatcg ccgacagaaa
    28201 atttttgcac ttcatcacct acagcaacaa ctttcccgac tccatcaaac cctaagatac
    28261 gtaaagcatt tcttatcccg ttatcttggc gaagtttcgt atcgacagga ttaacagata
    28321 ctgcgttgac ttttaccaga agatcccgtg aactgggtac aggtatctgt tctttttcat
    28381 caataaagct ttttggatca tcgatcgaca acccttcata aaaaccgact accttcatta
    28441 attccttttc tgacatacga attcctcctt agcttcatca agttggagca tccatacagt
    28501 tttcatttca atatatatag tatgctattt gttccacttt tattcatcat aattattctc
    28561 ttacttaaag taaactattt gcactttttt ggttaaaaaa gaggttgcga caagactttt
    28621 gtcacaacct cttttaaacg gtgttcaatc aactgaccct cggtattcgc tcaaaaaacg
    28681 acaaaatatg aggagctatt tttgtttggc tgttcttatt acttgatgca ggacagcttt
    28741 ttcacgacct ctaattcacg gtgttcaagc aagaaatcat tgttcactga aaagcgttgg
    28801 atgttctttt tcaaaggtgt ctaagatctc tcgtacttca tcagtagatt tcgtattcat
    28861 caactgaact cgcaagtcat ttgctcctgg aaatcctttg atatagattt taaagaaacg
    28921 atgtagtcct gtgatggaac gcgggatgat ttctgaataa tgatcttgca gatctagttg
    28981 cagacgaagt agtccgatca gttctttttc tgtatgttcc ctcggttctt tttcaaatgc
    29041 ataaggattc ttgaaaatcc cccggccaat catgatgcca tctacgccat atttttcggc
    29101 caattcttct cctgtctggc gatctgggat atctccgttg atcgtgatca gtgtttgcgg
    29161 agcgatttgg tcacgtaaag caatgatttt agggatgact tcccaatgtg catctacttt
    29221 actcatctct ttacgcgtac gcaaatggac agaaagattg gctatatctt gatgaagtag
    29281 gtgactgatc cattcttcca tctcagacat ttccgtatag ccgatacgcg tcttgacgct
    29341 gacaggcaaa ccgccagctt tagccgcttc aatcaattgt gccgctactt ctgggcgaag
    29401 gatcaagcca ctgccttttc cacgttctgc tacattaggg actgggcagc ccatgttgat
    29461 atcgattcct tggaagccca tttctgccat agcaatgctc atttctctaa aaaattctgg
    29521 cttgtctccc caaatatggg caaccatcgg ctgttcatct tctgtaaagg tcaatcttcc
    29581 tcgtacactg tcttttccat ctggatgaca gaaactgtct gagtttgtaa actcagtaaa
    29641 gaagacatcc ggtgctgctg catgctttac gacatggcga aatacaacat ctgttacatc
    29701 ttccattggt gctaaaacaa aaaaaggctt tggcagctct ttccaaaaat tagtagtcat
    29761 ttatttgtta ctctccattc tatcaagcag tgaagtcgca atctttctca aaaacattgt
    29821 cattatacta ggaaacaaaa aaagaagcaa agtgaacagc ttaaaagatg tttctgattg
    29881 agcaaaaaaa gactgtgaca aaaatcttat cacaattcct tttccggaat aaatggtgtt
    29941 caaaagcttg catctgcggt aataagtcca accaaacgaa aaataggagg agctattttt
    30001 gtttggctgt tcttattact tgatgcagaa cagctttttc acaacctctc cactaaacgg
    30061 tgttcaatca gctgaccctc ggtattagct caacaaacga caaaatatga ggaactattt
    30121 tcccgtttgt ttctctaata ctcaggtcaa aacgctgatt tcacaacctc ttttctaact
    30181 tctcaatcct cttcctttat tgatcaaata ccaagtaacg gcgtacaaaa caacgatgaa
    30241 tagcacaagt acgatcatcg atgttgctac tggcacatcg attgttccaa ggaatccgta
    30301 acggaaaccg gagatcatat aaacgatcgg attgactttc gaaacagctt gccaaaatgg
    30361 cggcaacata gagatggcat agaaaacgcc acctagataa gttaacggct gcaagacaaa
    30421 tgtaggcacg atcgatacat cgtcataaga ctgagcaaaa atcccgttga gcagtcctgc
    30481 taacgaaaac aagattgccg tcatcaataa tgtaatgatg accatgaacc atgaatacac
    30541 atgaagtggt acaaagaaca aggaaatgat cgttacgaga gagccgacga gaatactgcg
    30601 acccactccg ccaatcacaa agccccaaat gatcacatgc gtaggaacag gcgctaccaa
    30661 gatttcttcg atgtttttct ggaatttttg agagaagaag gacgaagaaa cgttggcata
    30721 cgaactagtg atagcagaca tcataatcaa accaggcacg atgaattcca tatatgaaaa
    30781 accacccatg tcaccgatcc gaccaccgat catttttccg aaaataacaa agtacaagga
    30841 tgtcgtgatc acaggcggaa ccagtgtttg gacccagata cgcaaatagc ggttcgtttc
    30901 cttgatagct aaacttttta atgcagtaaa ataaagatta aacatttttc tcctccgtat
    30961 gattattttc ttctgtgatt ttcaaaaaca gttcttctaa acgattcgac ttattcctca
    31021 tagaaagaac tttgattcct tgtcttgtca gctgatcgaa gattccgttc accccttgat
    31081 ttcgttcaac ttcgacagcg attgtctgtt catcttcaaa tgtacaagcg tatccttcaa
    31141 tcacaggttt ggtctcatat ggcgctaaat caaagataaa tgtttcaaat tgcagtttgg
    31201 atagaagctc tttcatacta gtattctcga tcagttcacc tgattggatg atcccgatgt
    31261 tgcgacaaag catttcagct tcttctaaat aatgcgtcgt caaaatgatc gttgtaccat
    31321 tttcgttcaa ttctcggaga aactcccaca tctcgcgtct caattcaata tcgactcctg
    31381 ctgttggttc atccaagatc agcaaacgtg gttcatgcat caatgcccta gcaatcatca
    31441 gtcttcgctt cattcccccg gaaagcatac gtgcacggac atttctcttt tcccaaagat
    31501 tggactgctt caaatatttt tcgctgcgtt tcatcgcttc tttgcgagag acaccgtagt
    31561 agcctgcttg attcacgacg atttgctgga ccgtttcaaa gggattgaaa ttgaactctt
    31621 gcgggactaa tccaatctgt tgctttgctc ggactagatc cgtatccaga tcataaccga
    31681 agacattcac ttttccagat gttttattga ctaaagaagt aatgattccg atcgttgtag
    31741 acttcccagc tccatttggt cctaatagcg catagaaatc tccttctttc acggaaagat
    31801 cgattcctcg caatgcttcg accccacttc cataaacctt tttcaaatta tttatttcaa
    31861 gcgcatttgc catttatttc ctatctcctt atagacatga ttctttattg tatcatggaa
    31921 tacagcagat gaaaaaacaa cttggttcca gcgaaaaatc aggttgctgg gctcaggaaa
    31981 atctcctaat gaaagacatc aatcggacga agtcagacaa ccttttcaga aaaaacaaat
    32041 cgaagataaa ggattactat tcatatgtgc aacaaaagga gcgtgagaca aaagtaaaga
    32101 acacttttgt ctcacgctct aaacacgtat aaacggcgga agcaaaagcc aagatttttg
    32161 atccaataaa tactttcgat cacttcgcct atcccaatac atgccactgc cgcttttcat
    32221 caaataacgc ggcttccgtt tttgcggttt ctactaaagt ctctgggtaa tccaaaactt
    32281 tcagcaaggc aatcgcattt cgggtccttg aaggtccttc ttttaatttg aaatcaaaac
    32341 tgattccttt tccttctgtt acttgttctt caaagtggac attctcacaa taattcttta
    32401 aaatctctgt caattcgata tcatgtgtgg cgacaaatgc taaagatgga tactccgcaa
    32461 gccaccgaac gactgaagcg gaagaagcaa tccgttcgat cgtatttgtc ccttttaaaa
    32521 tctcatctac gaagcagtag cagcgttctt tggaagccac ttggtccaac aaacgtttga
    32581 tcgatttgat ttctgaaaca aaataactgt cgccttcaaa taaatcatct tcgattgcca
    32641 tggaagtcaa cacatgtcca ggttgcaggg taaactgttc tgcaatcgct gtttggatcg
    32701 tctgtgctag aatacagctg atggctatac ttttgacata cgtagatttt cctgatgcat
    32761 tggaacccgt gactaatgta ttcttctgcc agttgaccgg attcactacc gcttctttta
    32821 acaatggatg atagatatct ttcgctgtca caccgccctc agtaaactct ggtcggcaag
    32881 tgatgggcat ataagtacgg taattcaata ttgcagcggc tacttctaat tctcccagca
    32941 attcccacag cttgatggct tcagttgaat gcttttctaa tttagtgaga acgaaatgat
    33001 aggagataaa tggcagcatg aacatgatgt tgacatattc aaaaatcaac tctgcttcac
    33061 tcccactctt catacgaaat gaaaaaccta atttagggat gtctcttaat ggtttagttt
    33121 gctgtttcag ctcttcttga agtggtgtcg gcagttttgc tagctgattg gcggctgaaa
    33181 tcgttgaaac caaataactc atgctattca gctctgtttc tagtgtttgt ttcttcacta
    33241 gataatagac cgtattgaat actaacccac cgattgccaa atagattcct agtacttgtc
    33301 ctaaaagaag caaacccaaa cccaccagcg gaagcaagcc aagaaaaata aataaaccta
    33361 cgcgtccaat ctttttactt tttccatccg ctagatattg ttttgcaaaa ttatgatctt
    33421 tttttcctaa acgagcgaat tgatattgga ttttttctct cagttgagga ttttcctgat
    33481 aaaaagcaat cagtttttct aactgctgat cttcaccaaa atcaaagctg cgtaaacgtt
    33541 gatacaacgc ttctgaacct acactagaat aggtactgtt gattccttcg aatacttcga
    33601 acatatccag gtcataccaa gtaagatcat cgatttcgct atcccatgaa cggaacttct
    33661 tctccgtgag ccatgcttcc ttcaagcttt cttctttatc aaatctcggt tgataaggaa
    33721 ttttttccca tttgctacga actgtttcct ttaatttcaa acgtgaaaaa atgtctaaag
    33781 caactaataa aataacagct gcaataataa ttaaaacgat aaattctctt tgacccatat
    33841 ccctctccgt tcctttattt gttagcttta gtatagcact gttgcgctat ttgaaaagag
    33901 ggtaaaaaaa cacctttcaa aataaaaggt gtttttttct tgtatattac atatttatct
    33961 ctcatttatc aaaattgaca aataatcata gggaggaatt gttgttaatt cttgtttatt
    34021 ctccagtgca ttgacaactg tcccaaggga aaggatagcc tcaggtacta ttttttcttg
    34081 ttctgttgga ttagctaagc gaagaacaaa tccttgttca tgaaaataag aaggataaat
    34141 cgatgataca attaagtctt caggtaattc aatcaatgaa aatttacgag gaacatcaag
    34201 ttcattttgt aatggccaaa tcttgttatc taacctgtga ataaatacat tcagtttctg
    34261 cttttgataa gaaatagatt gttctaaccg tttttctgcc tgttttgcca ctttgaactc
    34321 attaaatctt ccttcttcta cattaaatcc aaaagtgact ttatactcac ctatctcttg
    34381 agctagcggt gtttccatca tgacatgccc ttcatttgtc gtatctcctg aagctcgccc
    34441 aggtcgccaa gcaagattag gttttccaag ttcccctgtt gttgaaaata aggttatgat
    34501 taattgattt tctatacgtt catactcttt taaaccatct gcataaaacg taaaataatg
    34561 atcattttct gccacagaga cactcttatc gaatatttct aaattaacag gtttctctac
    34621 catagtttct gaccaattcg gaggaatgac atcaggggta ttttcaataa atccgttttg
    34681 aatttgtgca attgattttt cagatttatc taaaacatta attgctaagc gcatacgatg
    34741 cgagtaaaca gtattatgaa ttttgagtgt gccttcaacg atttgacttt ctcccagact
    34801 gaacgatatt tcataagata tttcttccat ttcgggtttt tcagataaac gatcttttaa
    34861 atctttagga agttgagctt ttccgtaaac aactaatgtt tcttgtaaag aatctttata
    34921 tactttagct gtttctaatt ttagagatag ttctgtatct ccttctaatg gtgaataatc
    34981 atacgtatcg ccatcatttg ctgaatcgat caaatgaacg aaatcaagat attgtctatc
    35041 tccaactatc aaattcaatt gcccatcttt aaaagaaagt ttatatttat tgttacttat
    35101 ctcagttttg tctatctcga ttgctgtttc taatttttca ttatttttct caaattcaac
    35161 aacagtgtat cctagtgctg gcacatttac atttattttt atgtcaagtt cataataagc
    35221 tggttcatca aaatattcga aacctgtagc aatcatccga taagcatttt tccgttctgg
    35281 aaaataaact tctttttcaa tgatattata gggactacct ttgaagtgta ttttctttga
    35341 atcagctact acatgcacga ttttcgatcc actataattc tcagtcgttg tgttgaaaac
    35401 aaggacttca ttcgatttta gctttaatgc atcagccatc cgttttacaa taaggttttc
    35461 gattccgtca gctatctcat tagcttcttt gattcgatgg aaaatatctt ccgcaacatt
    35521 atctgaaaca cagccaccaa tactatcatg agcctggttt tgcaaaatct ttttccataa
    35581 ccgacgaagt aggcctttac tgatatggat accatttctt tctgcaatca gcatgagcgg
    35641 ctcaactcgt tttagaattt tttgttccaa tttaaaattt tctattttca tttttgttct
    35701 tactgagcca atagaacgat gaacacgaga gtaaaccggc tgacgaagtt cacctttata
    35761 ttcaggtaat tcttttttgt ttctgataac ttctacataa gaaggataat ctgaaataat
    35821 attgtggaat ttactgtatt tattcaactt ctctacgact tgatcaaaat ttaaaatcat
    35881 tgacttttga tctacacccg aaggtactaa aatatctttg ttttttcctt gcatatgaag
    35941 catttcaact gcttcatcca acttttcttt tgcaaattca ggaatatctt taattgcgtc
    36001 taaggtcatc attccagtca tataaccaaa tggaaaattc atggcataaa caaatttatc
    36061 tcccaatcct ttccagataa aataaggaga tggaaccatc gtttcaaagt ttaatcctcg
    36121 ccaacacatg aaattatcga tttctacttg atgcaaaagt gtaggcaaat tcgcattgaa
    36181 cccaaacgtg tcaggcaaat accctaccat cattggatct ccatatttaa ggatcgtatc
    36241 actgattcca atcattaagt ttcttaaaat tgattcagca tccactaata aggcatctgt
    36301 ttgtgcatac cacggtccca cgaatagttg tcctgttttc atcagtcgtt ggataacctt
    36361 aagcttttgc ggattgatct ccaaatactc atcgacgatt gaagtttgtc catctaaaca
    36421 aaagtttact ttagggttcc tttccaattc atctagaact tcagtaaaga cctgatcaga
    36481 caatacgatg gcatcttcat ttgtaaaata ccattctctg tcccagtgcg tgtgttgaat
    36541 tatatgtgca tttaccatat cagattctcc tactttcctt cttctactga atttacttgt
    36601 tgttcttttt tatacttgat ggattttagt gcattgacca ttaacgctgt aaccactccc
    36661 ccaataacaa ttgatactaa atataaaggt atattcgtaa caaaaggaat tgccataaag
    36721 gttgaaagca ttgtttcttg agtaacacca aaaaatccat ttagaccaca tgctactgca
    36781 gtgcccacca cgatgcttgg tattactcgt aaaggatctt tcacggcaaa cgggatcgtc
    36841 ccttcagtaa tccccacaag gcccataatc atagctgtct ttgcattatc tcgttccgat
    36901 tcatcataaa gttttttgtt taaaattgtt gctaaaaaca ttccaaatgg cggaatagca
    36961 attcctaata acatggctgt actaggtcca aagcttccgc ttgaaaaaga agcaacccca
    37021 aaagcatatg cgattttatt gataggtcct cccatatcaa acgccatcat tcctcctaaa
    37081 atagccgaca tcaaagcagc atttgctcct gacatgcctt ctagccaatt agtcagtcct
    37141 gttgtcattg cttgaatagg cgtagctagt acataccata atatgattcc aacaactaat
    37201 gtagtaacaa aaggaatcag cataattgat tttagactaa taacttgcat cggtactttt
    37261 acttttttca atgcattagc taaatagcca caagctaatc cagcaaccat tcctccaata
    37321 aatcccatac caagattttg acacatcatc ccagtgataa aagctggtgc tagaccggga
    37381 cggtcagcaa ttgaatatgc gatataggct gaaatcatcg gtacgataaa ctgtaatccc
    37441 gtctgaccaa tcattcgcag gactccccag aatgtatccg tctggtccca aacacctgtg
    37501 ccaccaaaaa tgactgcaat agaagttagt aaccctgctg ctacgacaag cgggatcata
    37561 taggaaaccc cactttggaa atgatttaga atttctcttc cttgtttctt gaattccatt
    37621 agtaactccc ccacgatata ttttttattt gttaattaat gcaattgctt catcaatcgt
    37681 ctcttcacca tcttttacta cctctgaggt ccctactgtt aaaatcggtt taccgtcaaa
    37741 gcgacctcgt tctgaaacat ttgtatctac tgcaaatatg acaacatctg cctcggaaac
    37801 atccgaaatt gaaagtttgt tttctatccc catagccccc tgtgtttcta ctttaatatc
    37861 taaccctttc ttcttcgcaa acttttctaa attagctttt gccatataag tatgggcaat
    37921 ccctgcgata catgctgtta ctgctactat ttttgtcata tgaaattcct ccttttaaaa
    37981 tgatagagct tttaccaatt cttttttatt tctcgaatct tttattcttt taacaaactc
    38041 gtcatccatc aatcttccag ataattctgc taaaatacgt aaatgattag tacctttatc
    38101 agtgtctttt attgctaaca aaaagacgag atcaactggt tgatcatcta atgcgcccca
    38161 ttcaacagac cgctttaact tggctacagc cactgttgat tcaattactg ctaggctttt
    38221 gccatgagga atggcgatat ttttcccaat tcctgtggtc atatggtttt ctctgtcaaa
    38281 tacgtctttt tgaaattgtt tgtggtcaga cacaaaccca ttagtctcta acaatttcga
    38341 taatttttcg actacacttt ttttatc
//
LOCUS       DADVXE010000019        37356 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.019, whole genome shotgun sequence.
ACCESSION   DADVXE010000019 DADVXE010000000
VERSION     DADVXE010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.019"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            21..542
                     /locus_tag="KB913_001091"
     CDS             21..542
                     /locus_tag="KB913_001091"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6819470.1"
                     /translation="MHIGDKIHKLRRLNNETMNDLVKQTGLSKSWVSDIESGKKQRAD
                     FNKICAIAKHYKVSLEYFQDDYLDSDEHEDIIPLTDETRVKSVKSLEQSLKYLNNKQE
                     PNLLEIKLKDTDSVPEVYYKGQKLEGLIDVSYHYHTTTDVVAGSTNDINMEYLGEVTK
                     YPDIKTIGHKRDV"
     gene            543..860
                     /locus_tag="KB913_001092"
     CDS             543..860
                     /locus_tag="KB913_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBB6819471.1"
                     /translation="MKEARPRDEIDKLYKTKRWRDLRQVVIARDFGMCQECKRRGRNT
                     RGTIIHHIVEAREDLSLFWSVDNLECICVACHNREHPERSGGKKKPKPKSHIVKMYST
                     PER"
     gene            complement(1017..1181)
                     /locus_tag="KB913_001093"
     CDS             complement(1017..1181)
                     /locus_tag="KB913_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HBB6819472.1"
                     /translation="MGELYKPGEDNKPKGTYKEVGPRGGNVQGGREVKIDPGDRLPPT
                     SQKGNKWTKK"
     gene            1284..1805
                     /locus_tag="KB913_001094"
     CDS             1284..1805
                     /locus_tag="KB913_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBB6819473.1"
                     /translation="MPQPAKSAKLQLLNGNPNKKNTEELRKRAAAEDKLKMATDKIKP
                     PLWLDSLGKDTFEFIADELLSVDLISNPDVHTMALYSNWYSQYVSLEKQLRKLQREYK
                     LNYALAKKEAEARGEPFNEPNELIGNPLSRQMDTASRNLRSFGADLGLSPAARAKLAI
                     KMADDGGDDDDDF"
     gene            1792..2265
                     /locus_tag="KB913_001095"
     CDS             1792..2265
                     /locus_tag="KB913_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003666010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBB6819474.1"
                     /translation="MTTSNILDMSYTERVDYWQSYLEEQASWGGFLKCPYPELLTTWY
                     AERLIDGSIPASKENIQAAKRHMRDLQRQGTDDFPWIFDEEKGHRPIRYIEKKCKPTE
                     GDFGSFVLQPWQHFIIGSMYGWVHRDTGERRFREALIFVGRKNGKFCRLKIGQNR"
     gene            complement(2272..2430)
                     /locus_tag="KB913_001096"
     CDS             complement(2272..2430)
                     /locus_tag="KB913_001096"
                     /inference="COORDINATES: protein motif:HMM:NF024064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HBB6819475.1"
                     /translation="MDKYGLKNRIRISNAIDKDLYEGLKKMSEETMVPMSKLLDKAIE
                     LLLKESQK"
     gene            2523..3284
                     /locus_tag="KB913_001097"
     CDS             2523..3284
                     /locus_tag="KB913_001097"
                     /inference="COORDINATES: protein motif:HMM:TIGR01453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBB6819476.1"
                     /translation="MKKYIIYKHLNKINGKIYIGVTNDIGRRWRSGGIEYKPPKNETQ
                     HHRSFWNAIQKYGWENYDHLIIEEDLTMKEAFEKEKFYIELYDSTNKKKGYNIAKGGN
                     GGIIYKVHPKGMLGKKQSKEFSSNHSKWAKNHKNNCMTNGDVVWGVTHEHPKGMLGKH
                     HSKESIMKKKAYSGENAVTSKPIVAIERDGTKREFHSAKLCMAYYSISTCVFYRLLKD
                     GAPYVINPKANYRNKEKILAIEGIMFKHKEDTEVS"
     gene            3504..4823
                     /locus_tag="KB913_001098"
     CDS             3504..4823
                     /locus_tag="KB913_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003666013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBB6819477.1"
                     /translation="MVAYDDEQGANVYVLANARDQASLLFDKAAEMVKQSPALFKKFG
                     KPKRSSINYAPAFSKMEPRASDSRKLDGLNTHFGIFDEIHEFTNYNLINVIKKSRGTR
                     KQPLIVYITTAGYVLDGPLMSYFEQGVDCLEHLEDDIDERTFYYLAKLDSAEEADDPR
                     LWIKANPNICLMNFVGMLDDYVKDKKDPKEYADWITKQFNLFSDIDELSFVDMPTIKR
                     NNKTIDIETLKGKKCVGGFDLSETEDFTAAVLEFPLETGEVFILQHTWIPQARFDRDN
                     NQERIKAWEKVGDLTIIPGDYVNYEYVLNWFVENSKIYDIVKINYDKAKALRLNKELE
                     NAGFETNEIRQGFLSLGGPMQNFKEMLLDGKVIFNNSKLYRWYLSNVKLVMDRNSNWM
                     PSKQSKSRKIDGFAASLNSHAEVLNMLVNPVGTGKVTYYSISDLMNM"
     gene            4839..6059
                     /locus_tag="KB913_001099"
     CDS             4839..6059
                     /locus_tag="KB913_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6819478.1"
                     /translation="MSILDRLRSFGRAKPKASKQEYFLNDPGLIPYLVGKDEISEGIF
                     SVISRVSNVFASLPLKMIDAEFGQPDDCPAYNLLSEGPRYFTKFDFFRDVEVLRNYQG
                     NAYVQIFRNINGEVADMALIKPGACHPVIDMDSGELYYQVTATDKGSYKQVIYVHYME
                     MLHFKQPRFGGLEGTDPTKVLTNTLGYDREVRKISLSQLKGGNEGLKVKFASNVDEEA
                     KKATVKNIADFYRQNGGLLVEENGVEIERLQRELVDSKLLDTDKVSRSRIAMVYNVPE
                     HFIGSNQSSYSSQEQLNMEFLTYNLVPTVNQYEAELNKKTLSRTEKAKGYRYKFNVAS
                     LLRADTQARGQFYQIMRRGGAYSANDVRRFEDLQPINKTGMDDYHISGDLYPIDMDPT
                     LRKTNSSKSVAENG"
     gene            6094..6771
                     /locus_tag="KB913_001100"
     CDS             6094..6771
                     /locus_tag="KB913_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBB6819479.1"
                     /translation="MKKVTLSGDVVDNDTAWLYDWFGIDCISPGKISAALTEAAGDEV
                     ELDISSNGGDVLAASEIYTAIRAYPGKVSGNVVSIAASAASVIACACEPLRISPTAHI
                     MIHNAWVTTSGNAEELKANAEMLSSVDESIVNAYEIKTGLDRKKLADLMAKDTWLNAQ
                     TAVAEGFADEIMFAEAPVTVLNASQPVIPKNAVTKLKNLILKAETPQEETLLQKKLKA
                     LNGGKNE"
     gene            6768..7964
                     /locus_tag="KB913_001101"
     CDS             6768..7964
                     /locus_tag="KB913_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBB6819480.1"
                     /translation="MNLEQLKNAWVEAGSKVSDLNAQLNAALVDDEKTEEDVVSLQAQ
                     VKAARAKRDGLKEQVANMEAEQVLNVKKEPLDKKDENLKNKFIKDFKAMVNGDPAIMA
                     TLTSNTDESGNAIGLTIPVDVQTTIHTLVRQFDSLQEYVNVEKVTTTSGSRVYEKWSD
                     INPLTALDTEDGEIPANDDPALYLIKYLIKRYAGISTVTNSLLKDTAENILAWLSNWI
                     AKKVVVTRNTKILAAIDGIKAAQKKDVTDVDGIKDIINVQLDPAIEATSMFITNQDGF
                     NVLDKVKRADGSYLLQKDVASATGYTFLGKPIKKIASRFLPNKGTQATPKYPLYIGDL
                     KEAVTLYDRENMSLLTTNIGGGAFETDTTKVRVIDRFDVQLVDDEAVVLATFTSIANE
                     VPVTNG"
     gene            7979..8302
                     /locus_tag="KB913_001102"
     CDS             7979..8302
                     /locus_tag="KB913_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBB6819481.1"
                     /translation="MILDPKMDLDEIKNALKIDTDDDDVEVRRAVQAAIAYIRGAIGN
                     DKPSFYKQENDTVDLINLAILQLADHYYNARSATVSGNLREYDLGFTSLILQLKARYL
                     LFVEE"
     gene            8306..8641
                     /locus_tag="KB913_001103"
     CDS             8306..8641
                     /locus_tag="KB913_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBB6819482.1"
                     /translation="MPLIQTGNLNQRIKFVRDTTVKDEDGQVVRTSTTILTCWASVQT
                     QRLNDIKTSIGTALEGTLTFIIRYQQKSELTNDMKVRWNGKTFEIITITKGEFAKDFT
                     TIIAKEVSK"
     gene            8638..9033
                     /locus_tag="KB913_001104"
     CDS             8638..9033
                     /locus_tag="KB913_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819483.1"
                     /translation="MSVEVDATEVYKALREVKANVQRVESPALRKAGEYAQEKLQQNT
                     PYWDGTKSNGKRGSYMQEHAKDHVVTSSVKNGLIEVGYDKDVSWRMHFIEFGTIKQRP
                     KGFVQKTQKQIEKQVTQIIADEVKRRLGL"
     gene            9030..9401
                     /locus_tag="KB913_001105"
     CDS             9030..9401
                     /locus_tag="KB913_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819484.1"
                     /translation="MKTAVSQVYSILNSNEKTKNIDFYTNSVPESAQTVPSLPVGRIT
                     EIFGNYEDFASNNPLTIQFNVQVDVWVSTLKEVDAFYFALDEIMRGNGWQCAYTEQTD
                     DEDLEGAKRIIKRYVANISLN"
     gene            9417..9977
                     /locus_tag="KB913_001106"
     CDS             9417..9977
                     /locus_tag="KB913_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6819485.1"
                     /translation="MATVGFESVIFGVKTGAGGTLKELVADKSKGGAIEAKITGLGAT
                     SNTTYASNVPFFIASKGVSSPKVTLDVADLMDNGIYSEIIGAKTVDGVNVIGSETEAP
                     YVSVVMVTANKEGKRLFMGLAKGKFSHPDIDMKTAEDKGVELQTDSIEGEFISDERGY
                     VYLTAVESEEMTLQKFKDLVNNKAGE"
     gene            10104..10415
                     /locus_tag="KB913_001107"
     CDS             10104..10415
                     /locus_tag="KB913_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819486.1"
                     /translation="MIELQLKLDGKKKTFKQQDISARAMRECIKFYEKAEKADLTDLE
                     AIDSMIAITADIFQDPAVTFDAILDGLTASELVPALESVFEQINELGNNEKKQTASKK
                     R"
     gene            10439..10630
                     /locus_tag="KB913_001108"
     CDS             10439..10630
                     /locus_tag="KB913_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819487.1"
                     /translation="MDQIYKDLIESGWTMRDVDEADYHYLLHLFGEVESGEEYVDGAD
                     FIKQFLSAEDLVKLEEGGK"
     gene            10630..14475
                     /locus_tag="KB913_001109"
     CDS             10630..14475
                     /locus_tag="KB913_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBB6819488.1"
                     /translation="MAGKGQPAGNIKLGISLDSTNFGNTLDEINAKVKQAESNMRANL
                     KAYDSAGRSYEALSQKTKDLSTVMEGQNAKVRELTKRRDEAISKYGEESKQVANLNTQ
                     INNATAKYNAYSRQLNDTKKELVYSKTAVNDLSNEIKENERQMNAEVKALKAAGDESG
                     AFEAKQKGLAKQTELSEKAIEEQRKVVKLMADEFGDSANETEDAKRALEKLERQSQIS
                     SRQLEALKSSSDQSGKKIEDFGDKSTRSARKLDGLKDKLGSLKSAFSFGAVAGLAHNA
                     ISSVVSGVQGLVGEAVNASDSLMKFSKTMEFANFGKSQIESSKKEMKDYADKTVYGLE
                     EILNTTAQLASNGIPNYTELTKAAGNLNAVAGGSSDTFKSVAMMLTQTAGAGKLTTEN
                     WNQLADAIPGASGLLQDAMLKNGAYTGNFRDAMAQGQITSDEFNQAIVQLGMNDGAVK
                     AATSTDTLSGSWEQMKSTVINGLQSIIDKVGVENITGFINRVTKGIENSIPKITQFIG
                     WLRDIGTWIVENREPLTWIVGIIGGITLAVKALNVASMLLAITGGTLAAPFVAIGVAL
                     GALAGALVIAYTKSETFRNIVNAAFTAVKNVVMSVINNLVEYYKMLWSVLQWLWEKIK
                     EWASWIGNKFIEMKNSVVNTVQNLWNGVKNFFSNGVGDTWNKVVGWVKNIFNKATELK
                     NKVSDAIGNLWNGIKDTFRRGIDTVFNWFSELPTKMKNAIIGGKNAIVDAFKSIFNAA
                     LKAIGKPVNAIIHGASWVLEKLGADKLEEWKVPQYAKGTPNGGHPGGPMMVNDGRGAE
                     AVITPNGQAFIPRGRNVVLNAPKGTHVLTAEETAYMTGNKAPRYRYAKGTGFFGNLWN
                     NVKGFAGDVGNKLKDVVGDVWDFVTDPGALARKVLNGLGVLEGLVKYPLDVGKGILSK
                     ATEALTNKITELFSSGSLDTSMGMQGVYKYLADVAVAVMKKFPGFVATSGYRPGDPYS
                     HGKRNAIDIALPGVTGGSPRYTEAANYAFEKFANKIGYVITNGKVRDRSGQSGTGIHN
                     DWRPWPDGDHYDHVHLNGVKDPQNTQISGDSVGGSGVERWRNVAIRALKMTGQYSTAN
                     LNALLNQMRTESNGNPNAVNNWDINAKNGTPSKGLLQVIDPTFRQYAMPGFNSNIFDP
                     LSNILASIRYALSRYGSLTNAYRGVGYANGGIVNQHQIAEIAEGNKPEIIIPLDKAKR
                     SRAMQLLSIAMDKLGVSPKTYGNATTVSSDYEILEAIEKQAATTNQLLSLLLAFFKGN
                     SRTDRDLALDIQKILVRRM"
     gene            14476..15348
                     /locus_tag="KB913_001110"
     CDS             14476..15348
                     /locus_tag="KB913_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HBB6819489.1"
                     /translation="MRTVLLRNRINEEIDLSTEDYFATGLSNMGFEVKKEHVGQWGNF
                     RESSENVEISEFQSSVIISVHGFREKELYNSLVQFLSEGPFELEFAFDGETMVRRCSL
                     KSLSKTEIDPKTSLLTDTLELYFTSNWYSVKREKLIQRPNVVKTRGKVFPYKRSYIYT
                     QNLWEKKGVFKFNNNSVYLTNSKERMSPLKIRVIGKCSNPYWEVIQNSQIIATDGYFI
                     DMTETQTLEVSSLFEDTTAILKDIAGVESSVYQQQDYTKTNFVQAPTGEFSIVFHVGG
                     ADVEIELYEERDLF"
     gene            15345..16394
                     /locus_tag="KB913_001111"
     CDS             15345..16394
                     /locus_tag="KB913_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819490.1"
                     /translation="MILAVTLFHRDLMLYNEHLFSNSFEFGADEINEEASSFTMDKYV
                     PVKTGDFLLAKYIPSGKFAYFGVITSQEDEKISCKSLLSLADSEIPTARVSGDNYEEH
                     IRRLIEYYLLNDPTKQLKDILDVKAESATSHSYQATDTNKHKLSAYILNGFKKYNVKW
                     YFKGIQNRKIYTGIRAVNESIYIKDNSSEFSDWDVFVQAPGAGNENKLLIVDKAMKDI
                     EKPIILSTWYLDEENNLTQDGSKENITKPTVNLVNIYDQTAEDKASYEDVAKSELKGN
                     TYSHEIKVNVVRNAKNLNVETIETGMFATISYKGKIYKSVLTAWRISSDKEFVELTFG
                     NIRSRFMDYFEDNGG"
     gene            16398..17222
                     /locus_tag="KB913_001112"
     CDS             16398..17222
                     /locus_tag="KB913_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819491.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVTSTGSTVSISKISDSYELTLS
                     KGEILWSGTALMHDTQTVQPSKKMWQTVSGFLLVWLPYENGQAIGDRYVTTPFYKERV
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            17240..19372
                     /locus_tag="KB913_001113"
     CDS             17240..19372
                     /locus_tag="KB913_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2479 domain-containing protein"
                     /protein_id="HBB6819492.1"
                     /translation="MANLEIKLSANKRQPYLRHRVVGRVGDGGLTTINVQLLEEDEIT
                     PFVINLNGTLKFVGEVSNGNYTEGEPEIIDSTNGLISYTFTKSNFSTSHQFKQAYFEY
                     VDPNGKKVTFQNFIIDVLERVDINSEQAKYYISSLEKLQSEMQTTFNQFISDKQVQYD
                     QIYSKYNELVRLINESDKQVNDRIDKTNDRIDQTNQQIGDLGKLKKMYSNSIDFGDYD
                     YSGNPNLSAKLNASSFSLGTGATVADDNDEIVFTLDGTNQLSKYASKAQVPVAEGKQY
                     TISCEIMLEDGFTGDPSGIRLQHAYLPGGVVVLQTETVPKNELNTWQTLIGTRTVKYT
                     SDVPNEWYPLFRDIRTLKPTGKVRLRKIKIEEGSTATPYQPNLLDDPYWLGKAPLGEN
                     IANKSVTFPIKSSAYSLYQANMEEEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRY
                     GNLEPVEGLVDTWGLTFTPQKVGVNYPKRLTIIQYPQSTTGACQIDWLKIEKGNTRTP
                     NISEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEI
                     NSQLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSA
                     KLYREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQL
                     SIGADGAIKWRRNSSYGSDYTFAITYTI"
     gene            19389..19538
                     /locus_tag="KB913_001114"
     CDS             19389..19538
                     /locus_tag="KB913_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819493.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPILNWKPKFNY
                     WEGNK"
     gene            19535..19981
                     /locus_tag="KB913_001115"
     CDS             19535..19981
                     /locus_tag="KB913_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819494.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            19983..20120
                     /locus_tag="KB913_001116"
     CDS             19983..20120
                     /locus_tag="KB913_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBB6819495.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIISKEESA
                     S"
     gene            20157..20450
                     /locus_tag="KB913_001117"
     CDS             20157..20450
                     /locus_tag="KB913_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819496.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERSR"
     gene            20473..20670
                     /locus_tag="KB913_001118"
     CDS             20473..20670
                     /locus_tag="KB913_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBB6819497.1"
                     /translation="MILPDKYYQVIKWTVLTVLPALSVLVATLGKAYGWNGTDMAVLT
                     INAAATFLGVITGVSAYNLKK"
     gene            20681..21700
                     /locus_tag="KB913_001119"
     CDS             20681..21700
                     /locus_tag="KB913_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBB6819498.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGVNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
     gene            21957..22604
                     /locus_tag="KB913_001120"
     CDS             21957..22604
                     /locus_tag="KB913_001120"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6819499.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRGIIDES
                     DLNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQKVFNC
                     YKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFTK"
     gene            complement(22929..23075)
                     /locus_tag="KB913_001121"
                     /pseudo
     CDS             complement(22929..23075)
                     /locus_tag="KB913_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            23314..24006
                     /locus_tag="KB913_001122"
     CDS             23314..24006
                     /locus_tag="KB913_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6819500.1"
                     /translation="MNKKIVVSGLIIGGLVLAGIAGKNFADDILLWGGEDNIEQINHN
                     LESLDKALENKEQNISSLNSRLSSNNQELEQAKANVEEYKQKVLTLENDKNQLTIEKT
                     NLENQLSGKNAELQGKQNEINAKIDEINQKIAEINQLNTDWNNRLQTEQNKFNDAQNT
                     VNSLNQQINQLSNEKNTIKNQLQSTEQKLEKAQSENSNLNNYIEKLEKAKSDVEDTAN
                     RSQEIVTEHTGK"
     gene            complement(24288..24360)
                     /locus_tag="KB913_001123"
     tRNA            complement(24288..24360)
                     /locus_tag="KB913_001123"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24325..24327),aa:Lys,seq:ctt)
     gene            24741..25310
                     /locus_tag="KB913_001124"
     CDS             24741..25310
                     /locus_tag="KB913_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBB6819501.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            25297..26157
                     /locus_tag="KB913_001125"
     CDS             25297..26157
                     /locus_tag="KB913_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6819502.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            26347..27051
                     /locus_tag="KB913_001126"
     CDS             26347..27051
                     /locus_tag="KB913_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6819503.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            27056..28891
                     /gene="walK"
                     /locus_tag="KB913_001127"
     CDS             27056..28891
                     /gene="walK"
                     /locus_tag="KB913_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBB6819504.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            28888..30204
                     /locus_tag="KB913_001128"
     CDS             28888..30204
                     /locus_tag="KB913_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819505.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            30205..31074
                     /locus_tag="KB913_001129"
     CDS             30205..31074
                     /locus_tag="KB913_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBB6819506.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            31129..31938
                     /locus_tag="KB913_001130"
     CDS             31129..31938
                     /locus_tag="KB913_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6819507.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(32041..32670)
                     /locus_tag="KB913_001131"
     CDS             complement(32041..32670)
                     /locus_tag="KB913_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBB6819508.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            32840..34132
                     /locus_tag="KB913_001132"
     CDS             32840..34132
                     /locus_tag="KB913_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6819509.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(34208..34870)
                     /locus_tag="KB913_001133"
     CDS             complement(34208..34870)
                     /locus_tag="KB913_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6819510.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            35095..35379
                     /gene="groES"
                     /locus_tag="KB913_001134"
     CDS             35095..35379
                     /gene="groES"
                     /locus_tag="KB913_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBB6819511.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            35430..37055
                     /gene="groL"
                     /locus_tag="KB913_001135"
     CDS             35430..37055
                     /gene="groL"
                     /locus_tag="KB913_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBB6819512.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT        12894 a         6307 c         8099 g        10056 t
ORIGIN      
        1 tggattaagg aggaagagta atgcatatag gagataagat acataaattg agacggctta
       61 ataacgaaac aatgaacgac ttagttaaac aaaccggact gtcaaaatca tgggtatctg
      121 atattgagtc tggaaaaaag caacgcgctg actttaataa gatatgtgca atagccaaac
      181 attataaagt tagcttagaa tactttcagg atgattattt ggatagtgat gaacacgagg
      241 atattattcc tttgacagac gaaacaagag ttaaatcagt gaaatcgctt gaacaaagcc
      301 taaagtatct gaataacaaa caagaaccta accttctaga gatcaaacta aaagatactg
      361 actcagtacc agaggtttat tacaaaggtc agaagttaga gggattgata gatgtaagct
      421 atcactacca tacaacaact gatgtggtag ctggttcaac aaacgacatc aatatggagt
      481 acctaggtga agtaactaag tatccagata taaaaacaat cggacacaag agagatgtgt
      541 aaatgaaaga agctagacct agagacgaga tagacaaact atacaagacc aaacgatggc
      601 gagacctaag gcaagtagta atagctaggg acttcggcat gtgccaagag tgcaagcgtc
      661 gagggcggaa cacaaggggc acgatcatcc atcacatagt cgaggcgagg gaagacctgt
      721 cactgttctg gtccgtagat aaccttgaat gtatctgtgt agcttgtcac aacagagagc
      781 atccagagag atcaggcggg aagaagaaac caaaacctaa atcacatatc gttaaaatgt
      841 attcaactcc tgaaagataa gtttgcagcg aaatgaaggt agccccccta ctctaaaaga
      901 ttaaagagta aggcttgaga agaacggtgc tgtccttcct tcgtaaaaag accgcttttc
      961 aagttttttg gagaaaaagg aaaaagccga ccaatttaag ccggctttgg acgaagctat
     1021 ttcttagtcc atttgtttcc tttttgagaa gtaggaggta atcggtcgcc tggatcaatt
     1081 tttacttctc gtccgccttg gacatttcca ccacgaggtc ccacttcttt ataggttcct
     1141 tttggtttat tgtcttcgcc gggtttatag agttctccca taggaatccc tccctaaaaa
     1201 aatttcggca cagcactgcc gataacttaa ttataaggat tgtgataacg atttcaatat
     1261 atcttttgaa agaaggtgat attatgccgc aaccagcgaa gagtgcaaaa ttacaattat
     1321 taaacggaaa cccaaataag aagaataccg aagaactccg caagcgagcg gccgcagaag
     1381 acaaattaaa aatggctact gacaaaatca aaccgccgtt atggctagat tcgctaggaa
     1441 aggatacctt tgagtttatc gctgatgaat tgctgtctgt ggatttaatc agtaatccgg
     1501 acgtccatac aatggctctc tactccaatt ggtattcgca atacgtttct ttagaaaaac
     1561 agcttcgaaa actacaacga gagtacaagt tgaactatgc gcttgcgaaa aaggaggcag
     1621 aggcgagagg tgagccgttt aatgaaccta atgaattaat tggtaatccg ctctctcggc
     1681 agatggatac agcgtcgcgg aatctccgtt cttttggcgc tgatttagga ctatcaccag
     1741 cagccagagc taagttagct attaagatgg ctgatgatgg tggtgatgac gatgacgact
     1801 tctaatattt tggatatgtc ctacacagaa cgtgtggact attggcaaag ctatcttgag
     1861 gagcaagctt cttggggtgg ctttttaaaa tgtccatatc cggaattgtt aactacttgg
     1921 tatgcggaac gattaatcga tggaagcata ccagccagca aagaaaatat tcaagctgct
     1981 aaacggcata tgcgtgattt gcagcgccaa ggaacagatg attttccttg gatctttgac
     2041 gaagaaaaag gtcaccggcc tattagatat atcgaaaaaa aatgtaaacc aactgaaggc
     2101 gactttggtt cgtttgtttt gcaaccttgg cagcatttca taattggatc catgtacgga
     2161 tgggtacatc gtgatacagg agagcgtcgc ttccgcgagg ctcttatttt tgttggacgt
     2221 aaaaacggta agttttgccg tttaaaaatc gggcaaaatc ggtgaaaacc tttatttttg
     2281 gctttctttt agtaataatt cgatagcttt atcaagcaat ttagacatag gaaccatagt
     2341 ttcttccgac atttttttta atccttcgta taaatcttta tcaattgcgt tagaaattct
     2401 aattctgttt tttagtccgt atttgtccat gtgtgacact cctttttatt ttactataac
     2461 atccgattcc accgcttgca actaccatca attgatggta gtatataaaa gaggtgagta
     2521 gattgaaaaa atacattatt tacaaacact taaataaaat aaatggcaaa atttatatcg
     2581 gtgtcacaaa tgatattggc agaaggtgga ggagcggtgg gattgaatat aaaccaccaa
     2641 agaacgaaac ccaacaccac agaagttttt ggaatgcaat acaaaaatac gggtgggaaa
     2701 attatgatca tttgattatt gaagaagact taacgatgaa agaagctttt gagaaagaaa
     2761 agttttatat tgaactttat gactcaacta ataagaaaaa aggttataac atcgcaaaag
     2821 gcggaaatgg cggaataata tataaagttc accccaaagg aatgctaggg aaaaaacaat
     2881 ctaaagaatt ttcttcaaat cacagtaaat gggcaaagaa ccataagaat aattgtatga
     2941 caaacggtga tgttgtatgg ggtgttactc acgaacaccc aaaaggcatg ttgggaaagc
     3001 accacagcaa agaatcaatt atgaaaaaga aagcatatag tggtgaaaat gctgtaacct
     3061 caaaaccaat tgtcgcaatt gaacgggatg gaactaaaag agaatttcac agcgctaagc
     3121 tttgcatggc ttactattcg attagtacat gtgtttttta ccgactttta aaagatggcg
     3181 ccccttatgt gataaatcct aaagcgaact acagaaataa agaaaaaata ttagctatcg
     3241 aaggaattat gttcaaacat aaagaagata ccgaggtaag ttagtagatt gcgaaaggtt
     3301 actaactacc gtaacgcgta ggagttgaat aaatataatg ctcccaagag tgtccgacag
     3361 cagataattt gctgaaaatg tacgctaaac tgggccagaa ctgactgacc gatgaaaatg
     3421 agggtgacct ccagagtgcg agataaaaag ctcgcagata ataacaatcg aaaacatcac
     3481 taatttcagg cctttccaca tacatggtcg cttatgatga tgaacaaggc gccaacgttt
     3541 acgtattggc aaatgctcgt gatcaagcaa gcttgttgtt tgataaggcc gcagaaatgg
     3601 tcaaacaatc gccggcgctc tttaagaaat ttggtaagcc taaacgatca agtattaatt
     3661 atgctcccgc cttttctaaa atggaaccac gcgcctcaga tagccggaaa ttggatgggc
     3721 taaacactca ctttggtatt tttgacgaga tccacgagtt tacgaattac aatctgatca
     3781 acgttatcaa gaaatcaaga ggaaccagaa aacagcctct gatagtttat atcacaactg
     3841 ctggatatgt attagatggt ccgttgatgt cttattttga gcaaggtgtg gactgtttgg
     3901 aacatttgga agatgacatc gatgaacgga ctttctatta tctggcaaaa cttgacagtg
     3961 cggaagaggc tgatgaccca agattatgga tcaaagccaa tccgaatatt tgtctaatga
     4021 attttgttgg catgctagat gactatgtta aggataaaaa agatccaaaa gaatatgctg
     4081 actggattac caagcaattt aacttgtttt ccgatatcga tgagctgtca tttgtcgata
     4141 tgcctaccat taaacgaaac aataaaacca tcgatattga aacgctcaaa ggtaagaagt
     4201 gtgtcggtgg ttttgacttg tccgaaacgg aagactttac cgcagccgtt ttagaatttc
     4261 cgcttgaaac aggcgaggta ttcattttgc aacacacatg gatcccacaa gctagatttg
     4321 atcgagataa caatcaagag cgtatcaaag cgtgggagaa ggtgggagat ctaacgatta
     4381 ttcctggtga ttacgtcaat tatgaatacg tcttaaattg gtttgtagaa aattcgaaaa
     4441 tctatgacat tgtaaaaatc aattatgaca aggccaaggc gctacgatta aataaagaac
     4501 tagaaaatgc aggatttgaa accaacgaga ttcggcaagg gtttctatca ttaggtgggc
     4561 caatgcaaaa cttcaaggaa atgctattgg acggtaaggt gattttcaac aattccaagc
     4621 tttaccgatg gtatctatcc aacgtcaagc tggtgatgga tcgcaactca aactggatgc
     4681 cgtctaagca gtccaagagt agaaaaatag atggttttgc agcaagtttg aacagccacg
     4741 ccgaagtgtt gaatatgttg gttaatcctg tcggaaccgg gaaagtaacc tattactcga
     4801 tttccgattt aatgaatatg taagaaaggt gtggaggaat gagtatttta gatcgtttgc
     4861 gttcttttgg ccgagcgaag ccgaaagcga gcaaacaaga gtattttttg aatgacccgg
     4921 gattgatacc gtatttagtc ggaaaagatg aaatatcaga agggattttt tccgtaatta
     4981 gccgtgtatc gaacgttttt gcgtctctcc ctctcaaaat gatagatgcg gagtttggcc
     5041 aaccggacga ctgtcctgca tacaacttgt tgagcgaagg ccctcgatat tttacaaagt
     5101 ttgatttttt ccgggacgtg gaagttttga gaaactacca agggaatgcg tatgtgcaga
     5161 ttttccgaaa tatcaatgga gaagtagcag atatggcgtt aataaaacct ggtgcttgcc
     5221 atccagtgat tgatatggat agcggggagc tttactacca agtaactgcg actgacaaag
     5281 gcagttataa gcaagttatt tatgtacatt acatggaaat gctccacttt aaacaaccga
     5341 ggtttggtgg cttggaaggt acagacccca caaaagtatt aacgaatacc ctcggatatg
     5401 atcgagaagt ccgaaaaatc tctttaagtc agcttaaagg aggtaatgaa gggctaaaag
     5461 ttaagtttgc tagcaatgtg gatgaagaag ctaaaaaagc tacagttaaa aacattgctg
     5521 atttttatcg acaaaacggt ggactacttg tggaagaaaa cggtgtagaa atcgaacgtt
     5581 tacaacgaga gctggtagac agcaagcttt tagatactga taaagtatct cgctccagaa
     5641 tcgcgatggt ctacaacgtg ccggaacatt tcattgggag taaccagtcg agttactctt
     5701 cacaggaaca gctcaatatg gagtttttga catacaatct agtaccgacc gttaatcaat
     5761 atgaagcgga actaaataag aaaacactat cgagaaccga aaaagcaaaa ggttatcgat
     5821 ataagtttaa tgtcgcaagt ttgctaagag ctgacactca ggcaaggggg caattctatc
     5881 aaatcatgcg acgaggcgga gcatactcag cgaatgatgt ccgaagattt gaggacttgc
     5941 aaccgataaa taaaaccggt atggatgatt atcatatttc cggagaccta tatccaatcg
     6001 atatggatcc aacattaaga aaaacaaact cgtctaaaag cgtagccgaa aacggttagg
     6061 cttttttagt ttgcaccgaa gggaggtgaa aggatgaaaa aagtgacgtt aagcggcgat
     6121 gtcgtggata acgataccgc gtggttatat gactggtttg ggattgattg tatctcacca
     6181 gggaaaattt ctgccgctct tacagaagca gcgggggatg aagtagaact tgatatctca
     6241 tctaacggtg gggatgtcct agcggcaagc gaaatatata ccgctatccg tgcctatccg
     6301 ggaaaggtat ccggaaatgt tgtgagtatt gcagcaagcg ctgcaagtgt aatcgcttgt
     6361 gcttgcgaac cgcttagaat ctcgccaaca gcacacatca tgattcacaa cgcatgggtg
     6421 accactagcg gcaacgccga ggaattaaaa gccaatgcgg aaatgttaag cagtgtggat
     6481 gagtctatcg ttaatgctta cgagatcaag acaggactcg accggaaaaa gcttgctgat
     6541 ttaatggcaa aagatacttg gttaaacgca caaacagcag tggcggaagg ttttgcggat
     6601 gaaattatgt ttgcagaagc accagtaacg gtactcaatg cctctcaacc ggttattcca
     6661 aaaaacgcgg taactaagtt gaaaaatcta atactcaaag cggaaacacc gcaagaagaa
     6721 acgctcttgc agaaaaaact aaaagcctta aatggaggga aaaacgaatg aatttagaac
     6781 aattaaaaaa tgcgtgggtc gaggcgggaa gtaaagtctc tgatttaaac gcgcaactca
     6841 atgcagcatt ggttgacgat gaaaaaacag aagaagatgt agtaagtttg caagcacaag
     6901 taaaagcagc acgggctaaa cgggacggat tgaaagagca agtggcaaat atggaagccg
     6961 aacaagtctt aaacgtcaaa aaagaaccat tagataaaaa agatgaaaac ttgaaaaaca
     7021 agtttatcaa agactttaaa gcgatggtca atggtgatcc tgctattatg gctactttga
     7081 catctaatac ggatgaatct ggtaatgcta tcggattgac tattcctgta gatgtgcaaa
     7141 cgactattca tactttggtt cgtcagtttg actctttgca agaatacgta aacgttgaaa
     7201 aagtgaccac tactagcggt tctcgggttt atgaaaaatg gtctgatatt aacccactga
     7261 ccgctttgga tactgaagac ggtgaaatcc cagcaaatga tgatcctgca ctttacttga
     7321 tcaaatactt gatcaaacgc tacgcaggta tttctacagt aactaacagc ttgctaaaag
     7381 atactgccga aaacattttg gcatggttgt ctaactggat cgcgaaaaaa gtagttgtta
     7441 ctcgcaatac aaaaatcttg gcagctattg atggaatcaa agcagcgcaa aagaaagatg
     7501 ttacagatgt tgatgggatt aaagatatca taaacgtcca acttgatcca gctatcgaag
     7561 ctacatctat gtttattaca aaccaagatg gcttcaatgt tttagataaa gtgaaacgtg
     7621 ctgatggatc ttacttgtta caaaaagacg tagcttctgc aactggatat accttcttag
     7681 gtaaaccaat caagaaaatt gcttctcgtt tcttgccaaa caaaggtacg caagctactc
     7741 ctaaatatcc actgtatatt ggtgatctga aagaagctgt tacattgtat gatcgcgaaa
     7801 acatgagctt gctgacaacg aatattggcg ggggggcttt tgaaacagac accaccaaag
     7861 tacgggttat cgatcgattt gatgtgcagt tagtcgatga tgaagcagtt gttttagcta
     7921 catttacatc tatcgcaaac gaagtgccag taacaaacgg ttaaggagct gatttcttat
     7981 gattcttgat cctaaaatgg atttagacga aatcaaaaac gcactaaaga ttgataccga
     8041 tgatgacgat gtggaagtaa gacgtgcggt gcaagctgca attgcataca ttagaggggc
     8101 tatcgggaat gataagccct ctttttataa gcaagaaaat gacacggttg atctgattaa
     8161 tttagctatt ctgcaattag cagatcatta ttacaacgct cgatcagcaa ccgtgagtgg
     8221 gaacttgcga gagtacgatt taggttttac aagcctaatc ttgcaactca aagcaagata
     8281 tttgcttttt gtggaggagt agcgtatgcc ccttattcaa acaggaaatt taaatcaacg
     8341 catcaagttt gtccgagata cgacggtcaa ggacgaggac gggcaagttg tccggacttc
     8401 tacaaccatt cttacttgct gggcaagtgt gcagacacaa cgcctgaacg atattaagac
     8461 gtccattggt acggctttgg aaggaacact gacgttcatt atccgctatc aacaaaaatc
     8521 agagctaacc aatgatatga aagtgcgttg gaatggaaaa acgtttgaaa tcattacgat
     8581 tacgaaaggc gagtttgcga aggacttcac gacaatcatt gcaaaagagg tttcaaaatg
     8641 agtgtagaag tcgatgcaac cgaagtgtac aaagcgctta gggaagtaaa agcaaacgtt
     8701 caacgagtgg aaagcccagc acttagaaaa gctggggagt acgctcaaga aaagttacaa
     8761 caaaacacac cttactggga tggaacgaag tcaaacggta aacgtggttc gtatatgcaa
     8821 gaacatgcta aggaccatgt ggttacaagc tcggtaaaaa acggattgat agaagtcggc
     8881 tatgataaag atgtttcttg gcggatgcac tttatcgagt tcggaacaat caaacaacgt
     8941 ccaaaaggtt tcgtacaaaa aacacaaaag caaatcgaaa aacaagtaac acaaatcatt
     9001 gctgacgaag taaaaaggag gctaggactt tgaaaacggc agtatcacaa gtctattcaa
     9061 ttctgaatag caatgaaaaa acaaagaaca ttgattttta caccaatagt gttccggaat
     9121 cggctcaaac agtacctagc cttccagttg gcagaattac agagatattc ggcaactatg
     9181 aagatttcgc aagcaacaat cctttgacca ttcaatttaa cgtacaggta gatgtatggg
     9241 tatcgacctt aaaagaggtt gatgcctttt attttgccct tgatgagatt atgaggggga
     9301 atggttggca atgcgcatac acggaacaaa cagatgatga ggatttagaa ggtgcaaagc
     9361 ggattatcaa acgatatgta gcaaatattt cactaaatta aaaggagaga aaatagatgg
     9421 caacagtagg atttgagagc gtcatttttg gcgtaaaaac aggtgcaggc ggcactctaa
     9481 aagaattagt agcagataag tcgaaaggcg gagcgatcga agctaaaatt actggattag
     9541 gcgcaacttc taacacaaca tacgcttcaa acgtaccatt cttcattgca agtaaagggg
     9601 tttcgtcgcc aaaagttacg cttgacgtgg cagacttaat ggataacggc atttacagcg
     9661 aaatcattgg cgctaaaacc gtggatggtg taaatgtaat tggttcagaa actgaagcgc
     9721 cttacgtgtc ggtagtcatg gttacagcga acaaagaagg aaaacgctta ttcatgggat
     9781 tggcaaaagg aaaattcagt catccagata tcgacatgaa aacagctgaa gacaaaggag
     9841 ttgaattgca aaccgattct atcgaagggg aattcatttc tgatgaacgt ggctatgtat
     9901 acttaacagc cgtagaatca gaagaaatga ccttacaaaa attcaaggac ttggtaaata
     9961 acaaagcggg ggagtagtta accctgcatc tacaccaacg acagatacag ggacaccaaa
    10021 agaaccagaa ccaaaaattg atacacaagg ttagccattt tttggctagc cttatttttt
    10081 tgtaaaaaca aggaggaaaa caaatgattg aattgcaatt gaaacttgac ggaaagaaaa
    10141 aaacattcaa acaacaagat atttccgcac gtgcaatgcg tgagtgtatc aaattttacg
    10201 agaaagcgga aaaagcagac ctaactgatt tagaagcaat tgattcaatg attgcaatta
    10261 cagcagatat tttccaagat ccagcagtta catttgatgc tattttagac ggtttgactg
    10321 cgagcgagtt agtaccggca ttagaaagtg tttttgaaca aatcaatgaa ctgggaaaca
    10381 atgaaaaaaa gcagacggcg agcaaaaaga gataagtttt tctgaagcta ggaaagcaat
    10441 ggatcaaatc tacaaagatt taatcgaatc aggttggacg atgagagatg tggacgaagc
    10501 cgactatcat tatttgttac acctttttgg agaagtggag agtggcgaag aatatgtaga
    10561 tggtgctgat ttcatcaaac aatttttatc ggctgaagac ttggtaaaac ttgaggaagg
    10621 aggtaaataa tggcaggaaa aggacaaccg gcaggaaata tcaagctagg gattagttta
    10681 gatagcacta attttggtaa cacgctggac gaaatcaatg cgaaagtcaa acaagctgag
    10741 tcgaatatgc gtgccaatct aaaggcttat gattcagcag gacgttcata cgaagcactt
    10801 agtcaaaaga cgaaagactt gtctacggtt atggaagggc aaaacgccaa agtaagagaa
    10861 ttaacaaagc gccgtgatga agcgattagc aagtatggcg aggaatcgaa acaagttgct
    10921 aaccttaaca cacagataaa caatgctacc gcaaaatata atgcttacag tcgccagttg
    10981 aatgacacaa aaaaagaatt ggtgtattcc aaaacagccg tcaatgattt atctaacgaa
    11041 atcaaagaaa atgaacgaca aatgaacgcc gaagtaaaag cgttgaaagc cgctggtgat
    11101 gaatctggtg cgtttgaagc aaaacaaaaa gggctagcca aacaaacgga attatccgag
    11161 aaagctatcg aagaacagcg caaagttgtg aaactgatgg ctgatgagtt tggcgattca
    11221 gcaaatgaaa ccgaagatgc aaaaagggca ttagaaaagt tagaacgaca aagccaaata
    11281 tctagcaggc aattagaagc actcaaaagc tccagcgatc aatcaggaaa aaaaatagaa
    11341 gattttggcg acaagtccac aaggtcagct aggaaactgg atgggctaaa agacaaatta
    11401 ggctcgctaa aaagcgcatt ttcgtttggt gcagttgctg gattagcgca taacgctatt
    11461 agcagtgtag taagtggcgt gcaaggcttg gttggcgaag cagtaaacgc atcggattca
    11521 ttgatgaagt tttccaaaac catggagttt gctaactttg ggaagtcaca gatagaaagc
    11581 tcgaaaaaag aaatgaaaga ctacgccgat aagacggttt atggtttaga agaaattctg
    11641 aacacaaccg cacaattggc atctaacggg attcctaact atacagaact aaccaaggcg
    11701 gcaggtaact tgaatgccgt tgcaggcggt tctagtgata cattcaaatc cgttgccatg
    11761 atgctaacgc agacggcagg agctgggaaa ctaacaactg aaaactggaa tcaattagca
    11821 gatgcgatac cgggcgcttc agggctgtta caagacgcta tgttgaaaaa cggagcttat
    11881 acaggaaact tccgtgatgc aatggcgcaa ggtcaaatca cttctgatga gtttaaccaa
    11941 gcgattgtac agttaggtat gaatgacgga gcagttaaag cagctacttc cacagataca
    12001 ttgagtggtt cttgggaaca gatgaaatct actgtaataa atgggttaca aagtatcata
    12061 gacaaagtag gcgttgaaaa tatcactggt ttcatcaaca gagtaacaaa agggattgaa
    12121 aattctattc ctaaaattac tcaatttata ggttggttga gagatattgg aacgtggatc
    12181 gttgaaaata gagagccact aacatggatt gtcggaatca taggcggaat tacattagca
    12241 gtaaaagcat tgaacgtagc aagtatgttg ctggcaatta ctggcggaac attggcagcc
    12301 ccttttgtgg cgattggtgt agcattaggc gcactagcag gtgctttggt gatagcttat
    12361 acaaaatctg aaacatttag aaatatagtc aatgcggctt ttacagctgt gaaaaacgta
    12421 gttatgagcg ttatcaataa tttggtggaa tactacaaaa tgttgtggag cgtgttgcag
    12481 tggctttggg aaaaaataaa agaatgggct tcatggattg gcaataaatt cattgaaatg
    12541 aagaacagcg ttgtgaatac ggttcagaac ctatggaatg gtgtgaaaaa cttcttcagt
    12601 aatggcgttg gagacacttg gaataaggta gttggctggg taaaaaacat tttcaacaaa
    12661 gcaactgaat tgaagaacaa agtttctgat gcaattggta acctgtggaa cggtatcaaa
    12721 gacacattcc gtagaggcat tgatacggta ttcaattggt tttcagaact accgacgaag
    12781 atgaagaatg ccattattgg cggtaaaaat gccattgttg atgcgttcaa aagtattttc
    12841 aacgcagcac ttaaagcgat aggtaaacca gttaacgcaa tcatccatgg agcttcatgg
    12901 gtactagaaa aactgggtgc tgacaaactc gaagaatgga aagtgccaca atacgcaaaa
    12961 ggaacaccaa acggaggtca tccgggcggg cctatgatgg taaatgacgg tagaggtgct
    13021 gaagcggtaa tcacacctaa cggacaagca tttatcccac gagggcgaaa tgtagtgttg
    13081 aatgcaccaa aaggcacaca cgttctaaca gctgaagaaa cagcttatat gactggaaac
    13141 aaagcaccaa gatatagata cgccaaaggt acaggctttt tcggaaatct atggaacaac
    13201 gtcaaaggat ttgctggaga tgttggaaac aagctgaaag atgtagtcgg cgatgtatgg
    13261 gattttgtaa cagacccggg agcgttggct aggaaagtgt taaatggtct tggcgtactg
    13321 gaagggcttg tcaaatatcc tttagatgtt ggtaaaggta ttctaagcaa ggctaccgaa
    13381 gcattgacga acaaaatcac agaactattc agcagtggca gtttagacac ttcaatgggc
    13441 atgcaaggcg tttacaaata cttggcggac gttgcagttg cagtaatgaa gaagtttcca
    13501 ggctttgtgg caactagtgg gtatagacca ggtgacccct attcgcatgg taaacgtaat
    13561 gccattgata ttgcactacc tggtgtcaca ggaggctcgc cacgctacac agaagcagcc
    13621 aattacgcat ttgagaagtt tgcaaacaaa atcggctatg ttatcacaaa tggcaaggtt
    13681 cgtgaccgtt caggacaatc aggtacaggt attcacaatg attggagacc atggcccgat
    13741 ggagatcact atgatcatgt gcatttaaac ggtgtgaaag acccacaaaa cactcaaatt
    13801 tcaggagata gcgtgggagg cagtggggta gaaagatggc gcaatgtagc aattagagcg
    13861 ttgaaaatga ccggtcaata cagtactgca aacttaaatg cattactaaa tcaaatgcgt
    13921 acagagtcaa atggtaatcc taatgcagtt aacaattggg atattaacgc caaaaatgga
    13981 acaccatcaa aagggttgct ccaagtgatt gacccaacat tcagacagta tgcaatgcca
    14041 ggattcaaca gcaatatttt tgacccacta tctaacatct tagcttcaat cagatacgca
    14101 ctatcaagat atggctcact aacaaatgcc tatcgtggag ttggttacgc aaacggtgga
    14161 attgtaaacc aacatcaaat tgcggaaatc gcagaaggaa acaagccaga aattattatt
    14221 cctttagata aggctaaacg atcaagagcg atgcaattat tgtctatcgc aatggacaaa
    14281 ctaggagttt ctcctaaaac ttatggaaat gcgacaactg tttccagtga ttacgaaatc
    14341 ctagaagcca ttgaaaaaca ggcggcaaca acgaatcagc tgttatcgtt attgctggca
    14401 tttttcaaag gaaatagccg aactgataga gatttagctt tagatattca gaagatcttg
    14461 gttaggagga tgtagatgcg aactgtatta ctgagaaata gaataaacga agaaattgat
    14521 ttgtctacgg aggattattt tgctactggg ttgagtaata tggggtttga agtaaaaaaa
    14581 gaacatgtgg gacagtgggg gaatttcaga gaaagcagtg agaacgttga aatatctgaa
    14641 tttcagtcat ctgtaatcat ttctgtgcat gggtttcgag aaaaagaact gtacaattca
    14701 cttgtgcagt tcctatcgga aggtccgttt gaactggaat ttgcttttga cggcgaaaca
    14761 atggtaagaa gatgcagtct aaaatcttta agtaagactg aaatcgatcc gaaaacatcg
    14821 ttactaacag acactttaga actatatttc acatcaaact ggtattccgt aaaacgcgaa
    14881 aaattaattc agcgaccgaa tgtagtgaaa acacgtggta aggtttttcc gtataaaaga
    14941 tcttatatct acactcaaaa cttgtgggag aaaaaaggtg tattcaaatt caataataat
    15001 tctgtatacc taacgaatag caaggaacgg atgtccccgc taaaaattcg tgtgattggg
    15061 aagtgttcaa atccgtattg ggaagtaatc caaaactcac aaatcatcgc aacggatgga
    15121 tacttcatag atatgactga aacacagact ctagaagtat caagcctttt tgaagataca
    15181 acggcgattt taaaagatat tgcaggggta gaatcttctg tctaccaaca acaggattat
    15241 acaaaaacta attttgttca ggccccgact ggagaattca gcattgtgtt tcatgttggg
    15301 ggggcagacg tagagattga gttatacgag gagcgtgatc tgttttgatt ttagcagtca
    15361 cgctttttca tcgtgattta atgctttata acgaacattt attctctaac agttttgaat
    15421 ttggtgcgga cgagatcaac gaagaggcta gtagctttac gatggataag tacgttcctg
    15481 taaaaacagg cgattttcta ctagcaaaat atattcctag tggaaaattt gcatattttg
    15541 gtgtaattac gtcgcaggaa gacgaaaaaa tcagttgtaa aagcttactt agtttagctg
    15601 atagtgagat accgactgca cgtgtgtcag gagataacta cgaagagcat atccggcggt
    15661 tgattgaata ctatttgctg aatgatccaa cgaaacaact aaaagatatt ttagacgtca
    15721 aagcagaaag tgcgacctct cattcgtatc aagctaccga tacgaataaa cacaagttaa
    15781 gtgcgtatat tctcaatggt ttcaaaaaat acaacgtaaa atggtatttc aagggaattc
    15841 aaaacagaaa aatctataca ggcatacgtg ctgtaaatga atcaatttac attaaagaca
    15901 attcttctga atttagcgat tgggatgtgt ttgttcaggc gccgggcgct ggaaacgaga
    15961 acaagctatt aatcgttgat aaagcaatga aagatataga gaaaccgata atactgtcaa
    16021 catggtattt ggacgaagaa aacaatttga cacaagatgg atcgaaagaa aatatcacga
    16081 aaccaactgt caatttggtt aatatctacg atcaaaccgc agaagataaa gcatcctacg
    16141 aagatgtggc aaaatcagag ttgaaaggca atacgtattc gcatgaaatc aaagtgaacg
    16201 ttgtaagaaa tgcaaaaaat ttgaatgtcg aaacgattga aacagggatg tttgccacga
    16261 tttcttataa aggaaagata tacaagtcgg ttttgacagc ttggcgaata tcaagtgata
    16321 aggagtttgt ggaattgact ttcggaaaca taagaagtcg ttttatggat tattttgaag
    16381 ataatggggg ataaaaaatg gttagcaatg tggatggata tcaatttgaa aacgtgaaag
    16441 taagcgcaga aaatgatgct agactttatc acgttttata taatcggaaa aatcaggtta
    16501 ttgatggtta cgatcagtct atgaatttat cttcaagcgg attaacagta aaagttgctg
    16561 caggagcagc gattattcaa ggtcgtatgg tcgttgttcg acaagaagaa agtataacag
    16621 ttccagcaaa ctcaagtggt tatatagcat taacagtgga tttgacacaa gaagttatac
    16681 ctggatctat tcttccagaa tcggaagaat atgaatggac taataatcaa gtcaagctag
    16741 aatttataac aaaagttata aaaggtaatt taaacaatgg tgataaggtc tataatttac
    16801 cactatgctc agttacttct actggatcaa ctgtttcaat ctcaaagata tcggatagtt
    16861 acgagctgac tctctctaaa ggagaaattt tgtggagtgg gactgcgtta atgcatgata
    16921 ctcaaactgt ccaaccttca aaaaaaatgt ggcagacagt ttcaggtttt ttattagtat
    16981 ggctcccata cgaaaacggg caagcaattg gggatagata tgtaactacg cctttttata
    17041 aagagcgtgt aacttttact aatgttttag gagaaattgt ttcaggattt gatgactatc
    17101 acaaaaagtg gtttagtaaa cgaataaact ataattcgaa tactaatata tttacaggtg
    17161 cagcaagcaa tgcaagtgga gataacgcaa atatggtgct taggtatata gtttcttttt
    17221 agttaggagg tatggaagag tggcaaattt agaaattaaa ttatctgcaa ataagagaca
    17281 gccttatcta cgtcaccgtg ttgttggtag agttggtgat ggggggctca caacaatcaa
    17341 tgtacaactt cttgaggaag atgaaattac accttttgta attaatctaa acggtacttt
    17401 gaaatttgtg ggcgaagttt caaacggtaa ctataccgag ggagaaccag aaataatcga
    17461 ttcgactaat gggttaatta gttacacgtt cactaagtca aatttcagca cgagtcatca
    17521 attcaaacaa gcatattttg aatatgtaga tcctaacggc aaaaaagtaa cttttcagaa
    17581 cttcatcata gacgtgttag aacgagtaga tattaattcg gagcaagcga aatactatat
    17641 ttcttcattg gaaaaattac agagtgaaat gcaaaccact ttcaatcagt tcattagtga
    17701 taaacaggtc caatacgatc aaatctactc gaaatataac gaattagtaa gattgataaa
    17761 tgaatcagat aagcaagtaa atgatcgtat tgataagaca aatgatcgta ttgatcaaac
    17821 caatcagcaa atcggcgatc tcggcaagct gaaaaagatg tacagtaaca gcatcgactt
    17881 cggggactat gattatagtg ggaatccgaa ccttagcgct aaacttaatg cttcaagttt
    17941 ttctttaggt actggcgcaa cagtcgcgga tgataatgat gagattgtgt ttaccttaga
    18001 tggcacaaat caactatcga agtacgctag caaagcgcaa gtgccggtag cagaagggaa
    18061 acaatatacg attagttgtg aaattatgtt agaagatggg ttcactggcg acccttcagg
    18121 aatacgtctg caacacgcat atttgccagg cggggttgtt gttttacaga cagagacagt
    18181 acctaaaaat gaattgaata cgtggcagac gcttatcgga acgcgaacgg taaaatacac
    18241 ctctgacgta ccaaatgaat ggtacccttt gtttagagac atccgaacac ttaaaccgac
    18301 cggtaaagtt agactaagaa aaattaagat tgaagaaggc tcaacagcca ccccatatca
    18361 gccaaactta cttgatgacc cttactggct aggtaaagcg cctttgggtg agaatattgc
    18421 taataagtct gttacgtttc caatcaaatc tagcgcctac agcctatacc aagctaacat
    18481 ggaagaagaa tttgttttag gtcaaaccta tacaattacc atgaaggcaa ccaaaccacc
    18541 tatccaaacg ttcattgttt acaacgagga tagtggagat tatagatatg gtaacttaga
    18601 gccagtagaa gggttagttg atacatgggg tctgactttt acaccgcaga aggttggagt
    18661 taactacccc aaacggttaa ctattatcca gtatccccaa tcaacaacag gtgcatgtca
    18721 aattgactgg ctcaagatcg aaaaaggcaa tactcgaacc ccgaatatta gtgagtataa
    18781 atatcgtggt actggtatgc gtgattcaaa caatccaaaa gattatgttt gggatctagc
    18841 accagaatat gtcgaagata atttggccac agatattaaa atttctgaaa ttactggtaa
    18901 agcaaacaat tataccgatg ggaaagtatc ggagattaat tcgcagttga ctgcttcaat
    18961 taatgaagta gacaccacag ctaaggatgc tcaaacaaaa gcgaatgcta atgcgactgc
    19021 tatagatgaa ttagacaata agatcgatga acgcattaat gatacagcta ctaccacatt
    19081 aacagttaca aacgggaata ccggatcagc aaagctttat cgtgaaggaa aaacagtttc
    19141 tatatatttt gtggctttaa acggaaaaag cagtggtgga aatgattcaa cgatactaac
    19201 aattccagaa ggctatcggc caccaattag ttttgagcaa ctggttggct cgatagaccg
    19261 ttctactttg aacagtgctc agttatctat tggtgcagat ggagccatta aatggcgaag
    19321 aaactcaagt tatggatcgg attatacctt tgcaattact tacacgattt agaaaagcgt
    19381 gaatcgatat gaaggcagca tatagaccaa ttgaacctta cggattcgag caaatcattg
    19441 tgaatgatga agaacattta ccggaagaat gcacagaagt cgaaccaccg attctaaatt
    19501 ggaaaccgaa attcaattac tgggagggaa ataaatgaaa aacatttgga aatatggacg
    19561 tactggcgga gagtacgcag gaaaagtatt ggacgacatg cttgtatccg ttccttacac
    19621 agatcagcca ccgcttgaag gaattcgtgc tgatggcgaa ccgttaacaa tcgctgatca
    19681 aatgtttgat cctaaattga atcaatggat tattttagcg aacgcactag atcacaacga
    19741 tttaaacaat ctcaaagcaa tgtatgagtc gttagaaaat gagaacggcg atttaaaaca
    19801 gatcaatgcc aaactcatgc taagcgatgt agcaattaaa caggaaaata ctgcattgaa
    19861 agaaaaagcg gatagtttag cacaaatcaa ttcaaaaatg atgcttgctt cgttacaaaa
    19921 tagcaaagac atttcagaaa ttaaagagca actaaatcca gcttcaaagg gaggtgagta
    19981 gtatgtttag ttttagcgat gtgaaaatga tgtatgattg gggctgtttt actgacgatc
    20041 aagttcgact attcgttcca ctatgcatta cagacgaaga agcagataaa atcattagca
    20101 aagaagaaag cgcatcttaa gtgatgcgtt tttatttaag gtaaaggagt tgtcacatga
    20161 tcaatttagg ggaatgggga acaatcgcag gatcaattac tgcgattgtt tctttgattt
    20221 tattagtaat aagaccagtc actgcatctt tctcgaagat tactgaaact ctttcaaaag
    20281 taagtcacaa tttagatttg ctgactaaag atttagaatc gagcaaatca gatcgattga
    20341 tgattcatga agaactaaag aaacacgatg aaagattaga tacacatgca gaaaaattgg
    20401 tagaacacac acaacaaatt aaaactttat ttagagaaag gtctcggtaa aaaagaaagg
    20461 agttaagaag aaatgatttt acccgataag tattatcaag tcattaaatg gacagtttta
    20521 acagtattgc cagctttatc tgtattagta gccacattag gcaaagcata tggatggaat
    20581 ggaacagata tggcagttct gactatcaat gcagcagcaa catttttagg tgttatcact
    20641 ggtgtgtcgg cttataattt gaaaaaatag gaggaaacaa atgaaaaaga aaattactat
    20701 tactgcgatg agcctattaa cggctctttt tttattgccg attaatgggt ttgcctatac
    20761 gattaacaat gaatttaatt taggtgtaaa cgaaggtagt tctcaagtag caaataatca
    20821 gtacatttta ctgcatgaaa cggctaatga aacagcaaca ggacgcaatg aagcgcagta
    20881 tatgcaacgt tcatggacta gcgcttatac tgcttatatt gtgggagacg gcggaattgt
    20941 ttatcaagtc ggtcaacctg gttatgtaca gtacggtgct ggttcgtatg ctaatgcaaa
    21001 tagtcctgtg cagattgagt tacaacacac acatgataaa gcaacgtttg agaaaaacta
    21061 caaggcatac gttgaattag ctagagattc agcaatgaaa tatggtattc cacttacact
    21121 agacacaccg tataatcaac cagggatcaa atcgcattta tgggtaacac aaaatatttg
    21181 gggcgatcat acagatcctt acggttatct ttctgaaatg ggcgtaagta aagaaaaatt
    21241 agcctatgat ttggctcatg gatttaccga tgaaaatccg acaacttcag atgataaacc
    21301 agtcattgat ccaactcgag caggtgctgc aaatcctacc ctgacagatg gaacaaatta
    21361 cgcccacatt gatcagttcg gagaaatcga aaacgcaaac ttacatgtgg ctggttggca
    21421 catcgctaac tataaatacg agtatatctt cattatggat tacaatactg ggaaagaatt
    21481 agctcgagta aaagctgatg gaatatatag accagatgta aatcaagctt ataatacttt
    21541 aggaaatgtt ggctatcatg tatcttttaa catgcgcaac ttccctaata agaaagtcta
    21601 tgtaatgatg cgggcaacga atgatccaga agggaacact aaaggcggag cacaagattt
    21661 tcatgataaa cgctggtatt taaatattcc gcaacgataa aaatagcccc tcgtttttga
    21721 ggggaagtac ataatgcaaa tttgtccata acttattgat tatcttgtaa aaatgcggta
    21781 atttaatagt tagtgagaag aggtgcttaa ttatagttaa aaaagaggaa atagaagcag
    21841 catgtaacca agcaaatgtt aggtttattg gagaagcttt atctggatat cctaagtata
    21901 aatacttaca caactggtta caaagtaaaa gtttttatct taataaagaa agatgcatgc
    21961 ctaataaaaa ttatagggtt tataaaagag gaactattgt atatgttgat tttggggtga
    22021 acgtgggtta tgagttatct ggtaatcatt ttgctattgt tttaaataat aaagataatt
    22081 cgaaaaatgg tgttgtatgt gtagtaccaa tctcttcaaa aaagaaaagt aattatgtat
    22141 ctgtaggaaa aatattagaa gttgctagta ttaaacaatt tataagccaa gctgataaat
    22201 taaaagagaa acttaggata attattttac tttcattaaa tagaggcatc attgatgaaa
    22261 gcgatttgaa tagttttatt aaagatattg aagctaaagg tgaaaagctt tcagtggaag
    22321 aagtagaaaa acgagctgta aaacataatt tggtttgcga gacaagggaa caagtaatta
    22381 aagaaataaa atcattatct gaagatatgg taaaatatca gaaggtgttt aattgctaca
    22441 agaaatatac acaagaatcc tatgtaatgc cacttaatat ccaaacgatt agtaaaaata
    22501 gaattagaag aattaacaag tttgatcctt ctggaaatat gaaggcacct ggaaatgtcc
    22561 tcaatgaagt agatgaaagt ttaaaaaaat attttacaaa gtaaacgata tttttgttga
    22621 catttttctg ttcgttagtt accatgtagt tatagaagga cgtaagcgcc tatttttaat
    22681 gtacacatcg ggacgtatgc gcccacatag aaacatagtt gagagacatc tatatggtgt
    22741 ctcttttttt attaatatgc aaaaaagtct agttttttca ataatattta tgtaataata
    22801 aattagccac cacaacaaag aatgaaatcc attattatct agtctagtcc attctttttg
    22861 tttgcagtat ttgtgatggc tttccgtacc cttagctcag ttggtcagag cagacggctc
    22921 ataaccgtcc ggtcgtactt ctcgtaatcc aggaaggccg tcagctccgt ccgcagtagc
    22981 gtgtttacgg ccagctccag atgggagcgg aataactcgt tcaaatcacc tttggtggct
    23041 agagtctgca ggagttctgt aataaaatcg ttcataggga agtcctcttt tctgtgaatg
    23101 ggtgtggtaa ctttattcta cagaagggac ttcctttttt ctatttacac aaaatatttt
    23161 atactctcaa atgtttgtat gcagttacat ctgactttat tcgaattaag gaaaagattt
    23221 ataaaaataa aataaaaaaa tatatattta aattgactta ttgtgaaatc attaactata
    23281 attagttcag tttatgttaa ggagaatgat gatatgaata agaaaattgt agtaagtgga
    23341 ttaattatag gtggattagt gttagcaggg atcgcaggga aaaactttgc cgatgacatt
    23401 ttgttatggg gtggagaaga taatattgaa caaatcaatc ataatttgga gtcattagat
    23461 aaagcactag aaaataaaga gcaaaatatt agtagtttaa attcacgatt atcttcaaat
    23521 aatcaagaac ttgagcaagc aaaggctaac gttgaagaat ataaacaaaa agtgttgact
    23581 ttggaaaatg ataaaaatca attaactata gagaaaacaa atttagagaa tcaattatca
    23641 ggaaaaaatg ctgaattgca aggtaaacaa aatgaaatca atgctaaaat tgatgaaata
    23701 aatcaaaaaa tagctgaaat aaatcaatta aacactgatt ggaataatcg tttacaaaca
    23761 gaacaaaata aatttaatga tgctcaaaat actgttaata gtttaaatca acaaattaat
    23821 caattgtcaa atgaaaaaaa tactattaaa aaccaattgc aaagtactga acaaaaacta
    23881 gaaaaagcgc aatcagaaaa cagtaatttg aataattata ttgaaaaact ggaaaaagcc
    23941 aaaagcgatg tagaagacac agcaaacaga tcacaagaaa tcgtgactga acatacagga
    24001 aaatagatgc attttttagt ttaaatttct ttaacaaaat agtattttgt tgctaaataa
    24061 tttttatttg aatattctac aatgatatct cccctcaaaa tggaggggaa gtacatactg
    24121 tgataatcta caggtttatt gactgattag gatgttatta aaaaataaaa tactaaaatg
    24181 catacccgaa tttcataccc gaaaaataaa aaatgccacc acgtacactc ttttcgaaac
    24241 tacctaagta gccaagaatg tactggtgac gtgggtttgg cacccaatgg gccgtgaggg
    24301 gctcgaaccc gcgacccgct gattaagagt cagctgctct accaactgag ctaacggccc
    24361 gtacaaaaag tacttaataa tagtagcact aagaatttta aaatgcaaga ctacatttaa
    24421 agaaaatcag aaaaatcttt acttccttat aggaaatcat tcatagatta ttcacatttg
    24481 ctcgctatta tataagcata ccaacaaaca aagttcttgc aagagaacaa accctaacac
    24541 ttttttcatt ttttactcct ttcccgccgt ctccccggcg ggtctcctgt tcttaacgat
    24601 aaaagacaag aaggcttagc cttcttgttt tttgttttca tggaatcccg ctaatcaaat
    24661 cacctagtta aagcaactag attgaatgtt tatcataagt ctgatatcat gtttatgaaa
    24721 tgaaaaaagg agcggttatg atggaaaaaa tgcgtcagca attaatggag tgggggaagg
    24781 aactagaaac attccgtctg cctcactggg aagaactccc tgacttagaa ctttatatgg
    24841 accaagtcag aacgttagtt gatcgttatc tttcacctgt gatacaagga gaaaagcatc
    24901 cattgcttac ctcttctatg gtaaacaatt acgttaaact aggtttgata ccagcaccag
    24961 ttaaaaaaag atataacaaa gaacacgtag catttttact tgcaatcact acgttgaaac
    25021 aagtattgac tattcctgaa atcaaagaag ggatattgtt ccaaggaaaa acagtaggaa
    25081 ttcgtgaagc ctataatcta ttttgcgatg aacaagaagc agctgtgtgg atggtcagcc
    25141 aattagcaca aggtaaatct catccgcaaa aattcgacca ggcaacccct gtagaatata
    25201 ttgctgtaag agcggcaact ttatcgtttg caatgaaact tcttgcggaa aaaacgattg
    25261 ttctagaaac cgaatattta aaagaggaga aaacaaatga aaaacaataa aatcgcaatt
    25321 ttagtagatt caggtacgga tgtgccagaa gaattgataa aaaaatacga gatgtatatg
    25381 atcccattga aaattattta taaagatcag gtatatacag ataaaattga cattacctct
    25441 gaagagatct atcaacgttt gccagaggaa atccctggta catctttgcc ggatggtgag
    25501 tcgatcacag aaatctttga gcaaatcaaa aaagacggtt atgaaaaggt acttgcggta
    25561 acaatttcca gtggattgag cgggacatat aatgtggttc gtttaattgc acaacagcaa
    25621 gaagaattgg aagcatatgt actagatacg aaaaatattg gtattggtgc aggtttttct
    25681 gcgatccaag cagcaaaatg gctggaagaa ggagtagaat gggatcaact gatcagtaat
    25741 ctgaatgagt tagtcgaaag aacaaaagtt ttctttaatg ttgcgacatt ggaatatctt
    25801 caaaaaggtg gacggatcgg tttagttgct tctattgtag gaaccgcttt aaagcttaac
    25861 ccaatcatct catgtaatga agaagggatt tattacacag taggaaaagc taggggacgt
    25921 aaaaaaagtt tggataaaac ggttgcttac gtcaaagaaa aaatcggtaa tgcaaaggtc
    25981 ttcaacttag ctgttgccca tggggatgcg aaagaagaag caattgaaat ggaagcgaga
    26041 cttaaaagag agttcccaca agcaaaccaa atctactttg gccagatttc tccggcatta
    26101 gtagtccaca ctggtccggg attattgggt gtcggtgtac aagttttaga aggataaatc
    26161 aaaaaaagga aacactgagg tgaaaatcag tgttttcctt ttttattgaa gttagaacaa
    26221 aaaataataa agtattttgc actttcattt taattttctc ttttgtttta taggcaaaga
    26281 tgaaacaaaa gcagaaatac ggtataatga gaaggtatga caataatata taagaggtgg
    26341 ctctttatga aaaaagtttt agttgtcgat gatgagaagc cgatttcgga tatcgtcaaa
    26401 ttcaatttag ccaaagaagg ctatgatgtt tatactgcat atgatgggga agaagccttg
    26461 gaaaaagttg ctgaggtaga acctgatttg attttacttg atttgatgct acctaaaatg
    26521 gacggcttag aagttgctcg tgaggtacgc aaaacttatg atatgccgat cattatggta
    26581 acagccaaag attctgaaat tgataaagtc ctaggcttag agttaggcgc cgatgattac
    26641 gtgaccaagc cattttccaa ccgagaatta gttgcacgtg tcaaagcaaa tcttcgtcgc
    26701 ggtgccacgg ctgcgaagga accagaagag gcagcacctg cggaattgac gattggtgat
    26761 ttgacgatcc atccagaagc ttacatggtg acgaaacgag gagaaacaat cgagttaaca
    26821 catcgtgaat tcgaactact cttttacttg gcgaagcacc ttggacaagt gatgacaaga
    26881 gaacatttat tacaaacggt ttggggttat gattattttg gagatgtacg aacagtggat
    26941 gtaactgtac gtcgtttgcg tgaaaagatc gaagataatc caagccatcc aaattattta
    27001 gtgacacgtc gtggtgtcgg ttactatttg cgtaacccag aacaggagta attggatgaa
    27061 aagaaaagtc cgcttttttc gatcagtcaa ttttaagatc gctattacct ttattctgat
    27121 tttattgatc tcgatcgaaa ttattggtgc ctactttata cgtggtttag aacgttccac
    27181 gatcaataca tttattaaag atatgaatca aacggtggaa tcattagcaa caacaatcag
    27241 cccggaattg aatcgaaaag ataatgcaga tgatgaagag gtaaatgcga atatcaaaag
    27301 atttattgaa aacagtgcga ctagcgatat catcgaaata cgggtcgttg acgaaaaagg
    27361 gatcatccga ggaacaaccg atgtcaatga acaaagcgct gtgggaaaga aaaatgatta
    27421 tgttgatatc aatgatttca cgactaaacg ttatgttgct ttagataacg acgataaacg
    27481 ggtgaatatc aatgttcaac cgatcctgtc cccgaccggc gatgccgtta tcggggctct
    27541 ttacgtcaaa agtaatatcg aacaaaaata ttcggaaatc aataacacag cagtcatttt
    27601 ctttactgcc tcactaattg cggcatttat ttcaatgatc gtatctgttt tagttgctcg
    27661 ttcgattaca cagccgatcg gtgaaatgag agaacaagcc attcgaatcg ctagaggaga
    27721 ctacagtcgg aaagtcaaag tgcatggaca agatgaactt ggacagctgg ctgatacctt
    27781 caatcagtta gctgaacgta ttgaagaagc tcaagataca atggaagctg aacgcaatcg
    27841 tttggatagc gtgctatccc atatgacaga cggcgtcatt gcgacagatc gcaggggtaa
    27901 agtcattacg atcaatgata tggctgtttc cttgctagat atcaaaaacg aggaagcaat
    27961 cggacaatcg attttgacac ttttagatat cgaagaagaa tatacgttgc ggaaattatt
    28021 agaagatcca aacgaaatgg tacttgaccg ttcaaccagt acattggaaa gtgatcagat
    28081 gatcttgcga gtagactttt ctatgatccg tcgcgaatca ggttttatca gcggattagt
    28141 agctgtcttg catgatgtga cagaacaaga aaaaacagaa cgggaacgtc gtgaattcgt
    28201 ctctaatgtt tcccatgaac ttcgtacacc gttgacaagt atgcgtagtt atatcgaagc
    28261 attgagcgaa ggtgcgtgga aagacgagga agtagcacca aattttttga aggtaacgct
    28321 agatgaaaca gaccgaatga ttcgaatgat caatgacctc ttaaatctat ctcgcatgga
    28381 tacaggtaat acccagcttc aattagaata tgtcaatttc aacgagttag tgaattttgt
    28441 tcttgaccgg tttgatatga tggtgggaaa tcaggaaaaa aattataaga tccgtcgtga
    28501 atttacgcaa agagatcttt gggtcgaagt agatacagat aaaatcatcc aagtagtcga
    28561 taatatcatg aataacgcga tcaagtattc accagatggg ggaacgatta cttgtcgctt
    28621 attagaaacg cataataacg tggttttaag tatcaccgat caaggattgg ggattcctaa
    28681 aaaagatctg aaccgagtgt tcgagcggtt ctatcgagta gataaagcac gtgcaagagc
    28741 acaaggtggg acaggacttg gattagctat ttctagagaa gtgattaagg cgcatcgagg
    28801 cgctatttgg gcagagagca aggaaggaaa agggtcgact ttttatatct cgctgccata
    28861 tgaaccttat gaggaggaat ggtgggaatg agaatctctg aaaaagtcgt tcgtatagga
    28921 ctcattttga tggttgcgtt aagcatatac ttctcttatg caatctggct gagcccagca
    28981 ggaaaaagtt caatcaacgt agatgagaca aacactcaaa tgatcgagtc tcaaagcaat
    29041 cgaaaaactt ccgaagtctt tcttccgctt catgttacat ggcaccattc gggaatgatc
    29101 caagaaacca acagtgaaaa tctcgtgtac cgattgcaat tgatcatcga taaagcaaga
    29161 tttggaaagc tttctgaagt agtttcagga gacaaatcac agtttgaaca ggtgaaaaat
    29221 ctgaactctg gttttgagtt ggcctataat gcgccttttt tgctaagaga atacaaggaa
    29281 gcatttgatt tagatttaga tgtgtcgaac ttggcaaaag aaagcgaaaa tatgtatttt
    29341 actagaatac aattcgatca aggaaataaa aaaatccgat ttttgaatta ttcgaaccat
    29401 ctcgtatatg aagcaaatat ttcgttgaat tggacagata tcaataaaga attaacagca
    29461 aaagacacaa aatggacaga aatgacaaca gaaccatcga cgatcgacac gcaatatgct
    29521 acgaaacatt cgatcaaact gaaaaagtat agttatatcc tgtcacagca accctataca
    29581 ctttttagaa atgctttttt ccagaaacca gatagcgtga aaaataatga tgaaagcaat
    29641 gaattgattt tttacggtgg gaatgaaaca atgtctatcc attcggaaac gcaagtagtt
    29701 gattttcgtg gagagctgcc agagaaaaaa gaaaatgcta gtgtattttc tgaaagtttc
    29761 ccctatatta gcaaattagg cagttcttta gggaacctca gatattttga ccgcagtgac
    29821 aatacgatcg attatcggat attcgtggaa ggcttcccgg tttttgggac agacagcaga
    29881 ggacagattg gtgtggaagt tggcggtgaa acgaatggtt ctgtgcaagt gaatatccaa
    29941 accagtttga atacgattca agtgccgata ccttcagacg aagaagtaga acttgcaagt
    30001 acgaatgaaa tcatccagca gttaaaagct aagggagcag atagcaacaa gattggttca
    30061 gtgatcgttg gctatacatg gcaaaatgtc aaagaaacga atcgtgtcgt tgatctctta
    30121 cctgaatggt atgtgaaata taaagataac tggtattcag ctaacgacct tctggaaaaa
    30181 ttacctggat tggaggcgaa ttaattggat ttcaaaaaaa tcgaatggat atttttcgtc
    30241 gcttttttag ggttgaatgt gtttttattc agcagttatc atgacgcggt ataccaagaa
    30301 aacaatgtca ttcgctctaa tcagactgaa tcaatccaac aacgtctggc tagcgacgat
    30361 atcacttaca cggggaagat ttcgtctgag aacaagcaag gctattatct tagcgcggag
    30421 cagaccaatc ttagcacttc attagcgaat tatcgcaagg ctggtaaaag cggcttgctg
    30481 gcaagtggtg tgtttttaga cggtgatgtt ttgacgaaat ctttatccag ttcagatgct
    30541 gaaaagaacg tgatcgatcc agataaaatt agtagttcct tggaagattt tttatctaac
    30601 aaagacaata ttttattcgg taatgattat gtgtacacga aaaacttttc tcatttagaa
    30661 gaagaaccac tagaaatcca agcaagccaa gagtatgaag gcatcccatt caatgatgat
    30721 acagcaaaaa tcgttctttc tttagaaaaa aacgataatg attatagcat cacgaaatac
    30781 atgcagacgc atttatctga tatcgagcag ctgcgcgaaa agacggaact gtatacggaa
    30841 gaggaagcaa tcaatacatt gtacatcaat aacaaaatac caagaggatc aaaaatttta
    30901 tggcgtcagc tagcttattc ctgtattctg aaagtccggg aaaaaaatgt gtatgttcct
    30961 gtttggcatg tagcgatcga aacaagcgat aaagtggtcc aaattgagag tgtcaacgct
    31021 ttcagcaata cgatcgtgac aaacaatact gtaccaaaag tggaagatca ataaaaaagc
    31081 gagtataatg aaaaaagttt acaaagtaag aagggaagta ggagtcaaat ggctgaagaa
    31141 aaaccagctt ttaaaatcag tatcctagca agtggaagtt cgggtaattc actttatatc
    31201 gaaagtgaaa aaaaacggct tttggtcgat gcaggactta gcggtaaaaa aatcacttcc
    31261 ttgatggctc aaattgatcg gacaccggac caattagatg gaatacttgt gacgcatgaa
    31321 catcgagatc atatacatgg cgtgggtgtc ttggctcgta agtatcattt ggatgttttt
    31381 gccaatcagc agacttggga agcgatggaa ccactgattg gaaatgtacc agtggaacaa
    31441 aaacatctat ttgagatggg gaaagtcaga acattcggcg atatcgatat tgagagtttc
    31501 ggcgtctccc atgacgcagc ggctccgcaa ttttatcgtt tccataaaga aaatcggtca
    31561 ttcgtcatgt tgacggacac cggatattgc agtgattata tgcgaggtgt cattgaaaat
    31621 gccgatggtt atttgatgga aagtaatcat gatcttgaga tgttacgcat gggaccttat
    31681 ccgtggaatt taaaacagcg tattttagga gatagaggac atctttccaa cgaagacggt
    31741 gcacttgtca tgactgatgt gatcggtaat cggaccaaac gaatctatct tggccatctt
    31801 agcaaggaaa acaatatgaa agaacttgct catttaacaa tggaaaatgt tttgaaagaa
    31861 aaagattttg gcgttggaca tgattttgaa atctatgata cagatccaga tgaagcaact
    31921 gagctatttt cgatttaaac agttcaatca ataaaaatat aaaaagcaga agataaaatc
    31981 aatcagggtt ggttttatct tctattttta tttttttagc atattaaaaa aataaccgta
    32041 ttatcgactg actacactga tgtgctgctt ttcatgtttc tcatccagta tctcatctac
    32101 taatgcaatc gcgtaatctg ccatgctgat cgtactgtcg ccagcagcgt ttctttgtaa
    32161 ataatcatca cttaacaaat aagtacctgt acgtttgcca tgtggatcaa ataaagaagc
    32221 tggactgata taagtccaat gtagattttt agattgtttc aattttaaca atccttcgta
    32281 catattgaaa gctgttggat agaagggtgc atttttaggt acttggtcaa tcatacgagt
    32341 cgtcttttct gtatctaaga ataacgaaga ggcaccccca acgacaatta agcgtgtatc
    32401 ggttccttca agcatctcaa tcaaatggga caaagaagtt tgatgcattt cttcttttcc
    32461 tttgggagcg ttgaaagcat caacgacaac atcaaaagat gcaagatcag tagttgtcaa
    32521 ctcaaataaa tccttttgta taaacggaac atctgatggc aatttttctg gatgacgcac
    32581 gattgccgtc acgtctaaat ctctggacaa tgcttcgtct aaaataaatg aacctgcatg
    32641 gccagtagct ccaatgagtg caattttcat aaaaaacctc cttttttatt cctgtccatt
    32701 gtaagcagtt gctgaatatt cgtcaaagaa tccgattttt gaaaagctca gtgcgcattc
    32761 ctttcatggt tcgtgatcat tgggtatagt taaattaaga aaactgattg ataaaaatag
    32821 aagttgaagg agataagaaa tgaaagagtg gttagatcgt gcctttttac caatgataac
    32881 atctgttgtg aatcttagac ccttaactgc tttgcgtaat ggaatgactt acacgatccc
    32941 aataattatt gttggctcgc tgtttttctt atttgctcat tttcctgtgg attacatcgc
    33001 tcagtggata gacaaaacag gattttctat gtattttaca caagtatacc aggctacatt
    33061 tgatgtgata gccttttgga tcgtttttgc cattgcatac gcttatgcaa aagaagaaga
    33121 catcgatcgc ttaccagtcg gcataacagc cttgtctgct tatctactgc ttattcagcc
    33181 actaaatact cagatagata ctgtctggac aggtgctgaa gggatactag gagcagttac
    33241 aactgggctc atcatcggat ggggctatgc acgtttagta agacttgcga aagggtggaa
    33301 gcaaagagag aagatacctg aaaatgtttg gcagtctttt acttcattga ttccaatcat
    33361 tgttatagtc acttttacgc ttatcggttc agcggttttt caacagttgt tcagaatgac
    33421 tgttgttcaa ggagtatgga catatgtcca gcttcccatt caatcgttca tagacacgtt
    33481 gtttggtgtg cttttattag gtttttttgt tccgttttta tggttatttg gtcttcatgg
    33541 atctgcgatg gtcaatgggt tggttagtcc cgtcttgcaa gcgaattcat tagcgaatgc
    33601 agaaatctta gcctcaggac aagagttgac ggtggcaaat ggcggacata tcgttactca
    33661 gcaatttctc gatcagttca tgacggttac gggtgctgga ttgacgttag gggctgtatt
    33721 ttttatgacg gtttttgcga aatcgaagaa atacagagaa ttaggaaatc ttgctctttt
    33781 accagccttt ttcaacatca atgaatcaat tattttttcc acaccgatcg tgatgaaccc
    33841 gatgatggct gttcctttta ttttcgcacc ggtcgtttca ggattgatta cctattccgc
    33901 tttatatttt ggattcgttc ctttatttac agcagtccaa gtcccttgga caacaccgcc
    33961 gatcctctcg ggtttcttag taggcggagt gcctgcagcg attttacaag gtatcgtgtt
    34021 gtcaattagt tttttcattt atttcccatt tttgaaaaaa atagattctg caaactgcaa
    34081 aaaggaaaga cagacaaaaa atgatggagc agcagaaaag atgaacgact aaaaaacaaa
    34141 aatactcctg tcgctttaga ttgggaaaat caccaatcta ggatgacagg agtatttata
    34201 gtcatgttta tactagccct ttttggacag ctaattgaac aagaacaact aatgtgttca
    34261 ttcctacgtg tgtgatcatc gatgtccaga tccgaccagt tgctttgtac tctaggctga
    34321 agaagaaacc taggaaaaag tagattagca gatgaccatc attatgagca aacgcaaaca
    34381 gcaaagagct gatcactgct ccgacccaaa aatttgaata tcgactgatg atccccagta
    34441 tactgcggcg gaatacgaac tcttccatga tgggtccagc aacagttgtc gccaaaataa
    34501 aagcgggtgc ttccatgatc atctggatga tattttgtgt attctcggaa ggggttgctt
    34561 tgccaaacaa tacagattct aacatgacag cgatgctttg cagaatcaat gcgacaaaga
    34621 ttccaaccaa tccataaata acaatctttg gagcagaagc tttttttacc gctgattcga
    34681 tcgctaaggg ttcacgttgc ttaaaataaa aaatagctag gacaacggcg cctagtatat
    34741 acatgactgc agttgctgtg atcaattcag acgtagattt tacaagtcct atcgaagcta
    34801 ggatcaaggg tgagataaaa attagaccat agcaaaaaat gctgaggaag ctatattttt
    34861 ttaaagacat gtaattcctc cttttaaggg ataacaagca tgcaaggcaa gcttatatcg
    34921 attgatttca attatatcat aatttcaata agcagctgtc agaataaaat ttcttttctt
    34981 tgatttaaaa gcttgcaaaa aagagggaga atgagtatta ttaaaaatgt aggttagcac
    35041 tcgaaggtta agagtgctaa cagattaaaa aaagagttat cggagggatt tatcgtgtta
    35101 aaaccattag gtgatcgcgt cattatcgaa gtcgcaaaag aagaagaaaa aactgtcgga
    35161 ggaatcgttt tagcttctgc tgctaaagag aaaccccaaa ctgggacagt tgttgcagtc
    35221 ggtgaaggcc gtttgttaga aaacggtgaa aaagttcctg ccgctgtaaa agcaggcgac
    35281 caagttatgt tcgaaaaata cgccggtaca gaagtaaaat acgaaggaaa agaatatctg
    35341 atcgtcgcag gaaaagatat catggcgatt gttgagtaaa tttggaagat aaaaaaataa
    35401 tcaaaaataa tcaatgaggt gaatcaatca tggcaaaaga attgaaattt gcagaagacg
    35461 cacgcgcagc tatgttacgc ggggtagata aattagcaga tacagtgaaa gtaacattag
    35521 gacctaaagg ccgaaatgtc gtactagaaa aatcttacgg ctctccattg atcacaaatg
    35581 atggtgtgac gatcgcaaaa gaaatcgaat tagaagatca ttttgaaaac atgggtgcaa
    35641 aacttgtatc agaagtagca tcaaaaacaa atgatattgc aggagacggt acaacgacag
    35701 caactgttct gacacaagca atcgttcgcg aaggtttaaa aaacgtaact gcaggtgcta
    35761 atcctctagg cattcgtcgc gggatcgaat tggcaacaaa agcagcagtc gaagaattgc
    35821 ataatatctc aactgttgtt gattcaaaag aagccattgc acaagtagca gctgtttctt
    35881 cgggttctga taaagttgga catttgattg ctgatgcaat ggaaaaagtt ggaaacgacg
    35941 gtgtcatcac aatcgaagaa tcaaaaggga tcgaaacaga actagatgtt gtagaaggta
    36001 tgcagtttga tcgtggttac ttatcacaat atatggtaac agataacgac aaaatggaag
    36061 ctgttctaga aaacccatat atcttgatca cagacaaaaa aatctctaac atccaagata
    36121 ttctgccatt gttagaacaa atcttgcaac aatcacgtcc attgttgatt attgctgacg
    36181 atgtagatgg tgaagcattg ccaactcttg tattgaacaa aatccgtgga acattcaacg
    36241 tagtagctgt aaaagctcct ggtttcggcg atcgtcgtaa agcaatgctt gaagatatcg
    36301 ctattttgac aggtggtaca gtaattactg acgatctagg tttagaattg aaagatgtaa
    36361 caatcgaaaa cttaggaaat gcttctaaag ttgttgtaga taaagacaat acaacgatcg
    36421 tagaaggttc tggagaaaaa gaagcaatcg aagctcgtgt gcaattgatc aaaaaccaaa
    36481 ttgctgaaac aacttctgat tttgaccgcg aaaaattaca agaacgctta gctaaattag
    36541 caggtggtgt agctgttgtt aaagttggtg cagctactga aacagaattg aaagaattaa
    36601 aattacgcat tgaagatgca ttgaatgcta cacgtgccgc agtagaagaa ggaatggtct
    36661 caggtggtgg tacagctcta gtgaacgtta tcagcaaagt ttctgctgta gaagcagaag
    36721 gagacgtggc aacaggtatc aagatcgttg ttcgtgcttt agaagaacca attcgtcaaa
    36781 tcgctgaaaa cgctggttat gaaggatcag tgattgttga taaattgaag aacgtggaac
    36841 taggcactgg tttcaatgct gctactggag aatgggtaaa catggttgaa gcaggtatcg
    36901 tagacccaac taaagtaaca cgttctgcct tgcaaaatgc cgcttccgtt tctgccttgt
    36961 tattaacgac agaagcagtc gttgcagata aaccagaacc agcagcgcca gcagctcctg
    37021 caatggatcc atcaatgatg ggcggtatga tgtaagaaaa agcaacttgc ttatctacaa
    37081 ctgatcatta gtgaaagaca gataaaaaga ggctggaaca gaagcgttta actccaagaa
    37141 ataagaagaa attcacggaa attgcttttc aaatttttgt gaatttcagc ttatttccga
    37201 aggagttgct tctgcttccg ctgtttatac gtgtttagag cgtgagacaa aagtgttctt
    37261 tacttttgtc ccacgctctt ttttgtgtgt aattataatg aaaatagtta tttttaatag
    37321 ttataatatt ttatctatta aaagtaaata tccatt
//
LOCUS       DADVXE010000020        35863 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.020, whole genome shotgun sequence.
ACCESSION   DADVXE010000020 DADVXE010000000
VERSION     DADVXE010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.020"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..339)
                     /locus_tag="KB913_001136"
     CDS             complement(<1..339)
                     /locus_tag="KB913_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6819513.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSL"
     gene            541..840
                     /locus_tag="KB913_001137"
     CDS             541..840
                     /locus_tag="KB913_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6819514.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            1105..1980
                     /locus_tag="KB913_001138"
     CDS             1105..1980
                     /locus_tag="KB913_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819515.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            1977..2195
                     /locus_tag="KB913_001139"
     CDS             1977..2195
                     /locus_tag="KB913_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819516.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            2182..4809
                     /locus_tag="KB913_001140"
     CDS             2182..4809
                     /locus_tag="KB913_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819517.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDV
                     RENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENV
                     QKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNE
                     LFRDTLNDPNPLFDNLLKK"
     gene            4824..5042
                     /locus_tag="KB913_001141"
     CDS             4824..5042
                     /locus_tag="KB913_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819518.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
     gene            6561..6875
                     /locus_tag="KB913_001142"
     CDS             6561..6875
                     /locus_tag="KB913_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819519.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(6928..7701)
                     /locus_tag="KB913_001143"
     CDS             complement(6928..7701)
                     /locus_tag="KB913_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819520.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            7806..8051
                     /locus_tag="KB913_001144"
     CDS             7806..8051
                     /locus_tag="KB913_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6819521.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            8207..9058
                     /locus_tag="KB913_001145"
     CDS             8207..9058
                     /locus_tag="KB913_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HBB6819522.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            9091..9765
                     /locus_tag="KB913_001146"
                     /pseudo
     CDS             9091..9765
                     /locus_tag="KB913_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
     gene            10022..10210
                     /locus_tag="KB913_001147"
                     /pseudo
     CDS             10022..10210
                     /locus_tag="KB913_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            10256..11221
                     /locus_tag="KB913_001148"
     CDS             10256..11221
                     /locus_tag="KB913_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6819523.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            11243..11455
                     /locus_tag="KB913_001149"
     CDS             11243..11455
                     /locus_tag="KB913_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBB6819524.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            11530..12006
                     /locus_tag="KB913_001150"
     CDS             11530..12006
                     /locus_tag="KB913_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBB6819525.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            12003..13811
                     /locus_tag="KB913_001151"
     CDS             12003..13811
                     /locus_tag="KB913_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBB6819526.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            13888..14103
                     /locus_tag="KB913_001152"
     CDS             13888..14103
                     /locus_tag="KB913_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBB6819527.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            14195..15058
                     /locus_tag="KB913_001153"
     CDS             14195..15058
                     /locus_tag="KB913_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819528.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            15095..15631
                     /locus_tag="KB913_001154"
     CDS             15095..15631
                     /locus_tag="KB913_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HBB6819529.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            15645..16067
                     /locus_tag="KB913_001155"
     CDS             15645..16067
                     /locus_tag="KB913_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBB6819530.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            15997..18396
                     /locus_tag="KB913_001156"
     CDS             15997..18396
                     /locus_tag="KB913_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBB6819531.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            18428..20419
                     /locus_tag="KB913_001157"
     CDS             18428..20419
                     /locus_tag="KB913_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6819532.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            20442..20693
                     /locus_tag="KB913_001158"
     CDS             20442..20693
                     /locus_tag="KB913_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBB6819533.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            20683..21912
                     /locus_tag="KB913_001159"
     CDS             20683..21912
                     /locus_tag="KB913_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBB6819534.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            21909..23990
                     /locus_tag="KB913_001160"
     CDS             21909..23990
                     /locus_tag="KB913_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBB6819535.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            24139..28059
                     /locus_tag="KB913_001161"
     CDS             24139..28059
                     /locus_tag="KB913_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBB6819536.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            28060..29004
                     /locus_tag="KB913_001162"
     CDS             28060..29004
                     /locus_tag="KB913_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819537.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            29008..29211
                     /locus_tag="KB913_001163"
     CDS             29008..29211
                     /locus_tag="KB913_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBB6819538.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(29511..29747)
                     /locus_tag="KB913_001164"
     CDS             complement(29511..29747)
                     /locus_tag="KB913_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6819539.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(29930..30316)
                     /locus_tag="KB913_001165"
     CDS             complement(29930..30316)
                     /locus_tag="KB913_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBB6819540.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            complement(30298..31626)
                     /locus_tag="KB913_001166"
     CDS             complement(30298..31626)
                     /locus_tag="KB913_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBB6819541.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(31587..31916)
                     /gene="mobC"
                     /locus_tag="KB913_001167"
     CDS             complement(31587..31916)
                     /gene="mobC"
                     /locus_tag="KB913_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBB6819542.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(32174..32544)
                     /locus_tag="KB913_001168"
                     /pseudo
     CDS             complement(32174..32544)
                     /locus_tag="KB913_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            32689..32874
                     /locus_tag="KB913_001169"
     CDS             32689..32874
                     /locus_tag="KB913_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6819543.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            33032..33199
                     /locus_tag="KB913_001170"
     CDS             33032..33199
                     /locus_tag="KB913_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819544.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            33817..34476
                     /gene="vanR"
                     /locus_tag="KB913_001171"
     CDS             33817..34476
                     /gene="vanR"
                     /locus_tag="KB913_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBB6819545.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            34479..35840
                     /gene="vanS"
                     /locus_tag="KB913_001172"
     CDS             34479..35840
                     /gene="vanS"
                     /locus_tag="KB913_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBB6819546.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
BASE COUNT        10165 a         8211 c         8949 g         8538 t
ORIGIN      
        1 tagcgaaaac gtatcactat atctttcttg aatgtcttta aagactttgt gaggtatttc
       61 tgggaagtcc ttaatatata gctcataccc tatatcgata aggtatgaag ttatatattc
      121 ttctaaagtt ccccatttaa tccagtcaat tgttgaatta gtgatagttg ataataattt
      181 cagcttttgt ggatttggta aattggtccc acgttcccag ttggatatgg tcgcacgtgg
      241 tgaattatct attttccttc caagttcttc catagtaaaa ccacatgaaa ggcgtaattg
      301 tttgattcgt tttcctgctt ctgaaggatt tggcttcatc ttttttctcc tttttatttt
      361 taaagatagt atatcatatt tataaaataa aagtatttaa aagtatttac tttttatctg
      421 gagtatgata ctttattctt ataaatacaa ataaatacat ttttttacgc aatttgtatt
      481 tatttgtact tataaaggta gaggagttat agaataatta attaaaaagg agaggttttt
      541 gtggaagcaa taaaattaat gatttcagaa gaacaggagg aaatgtttct aaagcagttt
      601 tatcaaattg ctacaaaagc tattgaaaag gctcaagaaa atgcggggat gacaagggaa
      661 tatctcaatc aaaaagaaat ggcggaatac ttaaatgtga gtgaaaactt tttaaaaaat
      721 gctgtgagaa atgagggatt gcccgtagtt gaattagggg caagaaaatt ttattcgaaa
      781 aaggcagtta atgagtttat gtttgctcga atgaaaagag gggaaaatat tggaagatga
      841 tgaagtagaa attataaaaa aatgctttaa aaaaagaaaa aaagtgttcc caaaagtttg
      901 cagactgggg gaacactcaa taataaagtg ctgagaaaac tttatttata gctattatat
      961 caaaaaagaa ggtgaaaagg tgttttcttc tggaaatgtt gtagttgaca aacttagaga
     1021 aataaatttt gacggaaatg taatccacac acatggtacg atcaattaag aaaaaaaacg
     1081 aaaaaaggtg ttgagaagcc ctatttgaat gcaatagtta tcttagcaga aattacctat
     1141 tggtatagac ctaaaaaaat ttttaacgat gatggtcagc tacttggtta tcaaaaaaag
     1201 tttcttgaag atattttgca aaaatcatat aagcaattaa gcaaaaaaac aggattatca
     1261 gaacgagcta taaaagatgc aattgtgtac ttagagaaaa aggggattat caaaagggtt
     1321 tttagaaata tttattatga gaaaagagca gttacattat caaatgttat gtacattgtt
     1381 ttaaatgtac ataaattgat agaaattact tttcctactt tggattgcga aaaaaaggag
     1441 tatatgccga aaattcgtca gaggggtatc gaaaaaaaga gatatgtctc tttaaaaaaa
     1501 ggtagaggta tgtacaaatt tgtatatacg tatacaaaga ctacttcaca gaacatatca
     1561 aagactactc tcgttatgga agaagaggat attaatataa agaggattta cagtaagatt
     1621 agtgttcttt atgacgcaaa taacgaagat ggtcgaaaat tatttcaagt gtatcactat
     1681 ttgagaaacg ctaatgtaga tacagaagat atcagaaaaa tcattgaata tttatctgaa
     1741 aatactcagt atcttattgc tgagtgtatt ataaaacaac atgaagcatg cttttttcaa
     1801 agaaaaactg aagaagggtt atacgattat gtaacatatt ttttgaatgg acttcagaaa
     1861 agatataaaa gtcaattttt agaaaatgta gagcctatag atcagttcaa aaaagctttc
     1921 gaaatcaaag agttacctga aattactatg cataattggt tgaaaggaga agaatcatga
     1981 ttaaaaatcg cttaatagat caaatgtggt gtcttgatca aaatacagat actctcgaat
     2041 taatcgagag tatctgcttc aacacagtag ttctcgattt aagagctgaa aatgacaatt
     2101 gtgtaactca tatcataatt aatcaaaaaa tggctcagca gctctctgag agcctaagaa
     2161 aatgggctga aggagaaaac tatgaaagca attaaagaaa aaatcgttag tagaaaaata
     2221 aactggttag cactcagtgt acttgtttta atgattagcg ttgtttttac aagtaatatt
     2281 gttgaagcta gcattttcaa ttggtttgat gacacaaaaa gtcaaacaga gtttttgaat
     2341 aattctcttt atagacctta cctaaaaaaa tacaatggag atttccttag tcagttcggg
     2401 atttggcttg gatgggctgt ggtaaaaggc atgtttactg tgactgattc gattcaaaat
     2461 atgattccag atgtgttgga tttgttcaat ttcattgaaa gtacagggct aaataatgtt
     2521 tatcaatcag tcataaatac aattgtcgtt ggattaatga tcctttcatt gatgtttgtt
     2581 ggctacaaga tgattactgg aaaaggaaca atagatttaa gatctgttgg aatgaatata
     2641 gtgatgtctg tagcgttaat tcttttaatg ccaacaatga tttctagcgg tattcaattt
     2701 gccaaaatat tttacaatga tgctactacg attacaaatt cagatgacgg agtcgcttgg
     2761 tcattgataa aacaaggagt aacagatctg gcatatatta ataaaacaga tcaatactca
     2821 agcattgata aaacggagga tcgaaataag ttaacacgaa aaaattttca acagacagat
     2881 ttaacacaag tgttgacgga taaagtgatt gataaattgg aaaaagaaaa tccagctgcg
     2941 gataatcttc gctatgaatt agttgaaaat tctaataatg aatttgttgc cacaaagttt
     3001 tctgataact tcttatcaac attttctgat agcttgaaat caggttatta tcgatatcaa
     3061 gcaaatcttt gggggatttc gattgggttg acagcgttgg caatcgccta tgtgttcagc
     3121 gcgtttgtga tcattacagc aatattagaa cttgcattta aacgtgtgtt aggtgttctt
     3181 gtttttgcga cagatattga aacaggacaa cgttcaaaag ttgttttatc cgatatttta
     3241 caatgttact taacagttgg atttcaaggg tttggactat ctatgtttgc tatgtttatc
     3301 aattttttaa atgctggaca aggtatctcc acaaatattt ttataaaaac aattgcttat
     3361 atctgtgctg tgtttgtgct gataaaaggc agtggaacag tcatgagata ctttggtgtt
     3421 gatattggac tcaaagaagg ctatgggcaa cttgcttctg cttttggtat gggcgcaatg
     3481 ctgtttagaa aaggatcaac tggatttaat cgtgctaaag gaagcggaaa tggaaatgga
     3541 tcagacagtg gagaaggaga agatcgaaaa ccagaaaaga atttcggcga aactctatca
     3601 aaaaaagctg gcaaaactgg aagagctttg ggatatgccc atgaacgtgg attatcaggt
     3661 ttagcttcag atggagctac aatggctagt gaaagagcaa taaaaccatt taagagtatg
     3721 cgtgatatgg ctaatgatac caagaataag ttcaaagaag gtttagatga tggtacagtg
     3781 tccgctatta ataaaaatag caaacctatg ttagctaaaa ataaagaaga tgaaactgga
     3841 aaatatgctg attccatgcc aacacgtctt tcggatagaa aagatggtgc taaggttgaa
     3901 aatgccgata gaattatgtc tagttctgaa cgtatgcgtg aagcaatgaa aaataatgct
     3961 gaatcgaata ataatcctgt aagtgcaatt cagcaaaaag ttcaacaaga tattgaagaa
     4021 cgtaaaaatg ctatgcacgg tcaagctaag tctgctgaag aattaattaa tcagaagcga
     4081 caagaagcta aatacacgcc tgaagcaatg aatcgtgagg aaatgttaag gaaacgtgta
     4141 gaagggcgta caggagctaa tacggacgaa aaagaagcgt tgaccaaaga aagaatccaa
     4201 gaagctaaaa actcaaatac cggattagaa aaattggtca aagaaaatct acaaaattct
     4261 acaagtagtc aaggtggccg atcagtagat gtccgagaaa atattcaagg ttcattgaat
     4321 ggtcatgtcg gacggaatgt tgatgtaaga gagaatttac aaagctcttc aaatggtcaa
     4381 ggtactaaga caattgatgt tcgagaaaat gtacaaaatt ctacaagtag tcaagggttt
     4441 aaatcaatgg atgtaagaga gaatgtacaa aattctacaa gtagtcaagg gtttaaatca
     4501 atggatgtaa gagagaatgt acaaagttct acaagtagtc aaggattcaa aacagtagat
     4561 gttcgggaga acgttcaaaa agatagtgga gaaatgaaag aaaaaacaca aaaaatcaat
     4621 atcgttgaag acagaaagtc agcgaaaaaa tttgattcaa atcatgaaac agtgattatt
     4681 gatagtgaaa tccgtgaaaa tgataaggga tcaaaaccaa gacgaagatt tacctatgaa
     4741 gacaacgagt tattcagaga tacacttaat gatcctaatc cgcttttcga taatctatta
     4801 aaaaaataaa agggggaatt gtcatgaaat taattctaaa gattagtacg catgatttct
     4861 tagaacttga cgaattatgt gaatcagtaa agaacgcaac aaatgaaaaa atcacggtca
     4921 ctaattatat tgaactgatg attcaagaag aattaaagat gaaacatgag ataaaaaaca
     4981 acttgaaata ttgttatcta gaaaaaagtg aagagataat ccatgaatta aatggctttt
     5041 aaaaattgta tttgacatga atttacgaca aggaattagt ggggattaag cgattattct
     5101 cttccacttt agagaaataa tgggttaaaa agccagaata cgtagagcaa tattgacaac
     5161 ctataaagga gctattgttg aaaattgaag taacaaaaag ataaagggag gtttacatct
     5221 atcagattaa aagtgatagt acacccatga aacctgcaaa agagttgaac ctaatgtata
     5281 tcggtttaac tctttttatt tgcaaattaa aaaaatatca ccgaagtgac gaatgaaact
     5341 atgaccaaat taagcaagaa aatatatctt gcaaataaag tagtataaaa agatattgat
     5401 aaagccaatc aaaactttga atttcaaacg ttagataatc aaacagatac aaaaaatgaa
     5461 atcagttcta cgcgtacgat tattaaaaat aataaatttt cactagaaga aaatggaaat
     5521 aaaatcaaat aattaggaag aaaaaacaaa gcaattagaa aagcctgcaa gcaaatttga
     5581 gtaatcgaga tccaattttt ttaaggaagt ttaacaaaaa tatgtaattc tattatcact
     5641 attaaagaga aagttggagc ggaatataaa gaaaagagaa aagtaattaa acgcaaaaaa
     5701 atgtagaact taaaaaatat aaagaggaac aaccgttaaa attaggaatg atgttgtgta
     5761 aacattataa ttgctatgat ataaatgaag tgttaaagaa agcaaattta aaccaatttt
     5821 gtgaacagaa aagccttagt cactatgacc aaaactacgg acgaaactat gaccaaaagt
     5881 aggtactaaa ttatgaccga aaataggtcc aaaatggatt tttttatgat atcaaaaatt
     5941 atgaaatgat tttgaaagaa aaccagttgg cacagccaac ttagccacct tcctgtagga
     6001 aggtgctatc agttttccct tatgctcttt tctttctttt ttgtttcata tgtcaaatgc
     6061 cattttgaaa tgtaccatct taagaaattt atccttaaaa acaattgcgt tattggataa
     6121 aaagatgcta cattatctta aaaaaggaat caaatatgat gaatttagtg gctagcatat
     6181 cgtgtgatta agatacttta tagtgtaagt tgaaggagaa aaaatattta aaatatactt
     6241 cccatttcag tgggaagtaa aattaatctt gttgtttcta ctagtaatgt atctttttgg
     6301 aaactatgta acgatgtaaa caagattttt ttcagaagaa aaaacgataa aagttgtgat
     6361 aaacgattta aaaaatagga gaaaatatat caagcgcatg gtatgaaacg cacatttaaa
     6421 aagattcgac taactaaaaa aataagttta caaagcattg ttgtgtatta caagtgatct
     6481 atacactgaa aaatgataga gaaaatctga tacgtccgca acaatggaca attgaaaatg
     6541 aaagtgagga aattggaaga atggctgatg aaaataaagt tgttccgctt gaaacactag
     6601 tgataaataa ggaagagttt gagcaacttt ttcttgattt ttttgttcaa tatgacagga
     6661 tttatgattt tagttcgtca ctagatttat ttgaattaga ggcagaaata atagaaaaca
     6721 gtcgagagga gaatggtaaa atcatcattt cagtagaaaa attcaatgaa ttattctcag
     6781 aaacatttga aatagataca gattattatc aaccacaaga agttttccaa tcatttagaa
     6841 atcagattat tcgctcaggt aagaccgtaa actgaaaaac aataaaagaa acgttgaaag
     6901 aataattatt ccttcaacgt ttctttttta gaatgtttta atgaccaaag cagtttcatt
     6961 gtcaggctta ggtaattcat gaaatcccgt atttatagtg ctcaattgat caactaacca
     7021 tgttttactt tttgaattgt agataaatct aaaattaata tcgttattat cgtgttgaag
     7081 gggcgtctcc aaataatctg ctgtatattc atagtcaacg taacctgcta atacaaaaga
     7141 gagtatccct ttatttaatg ttagatttaa tggataatca tacgacttta tttttttcaa
     7201 cttcatattg tacatatctt cagccataaa agttgagttc gtgatttcat cttgggtctc
     7261 attaaaaaag ttatccgaat aatcgcttat ttttgaaaag tctttattgg caccagcctc
     7321 aaaaaattgt tcaacttttt cagtataaag ttgtgctaac gctccttttt caatattaac
     7381 tttaatattt tcatgtctat caatttgtgt gctgttcagt aagggaagat cagcttttag
     7441 ttttatatcg tcttgatttc tttcaatttc aattggcaaa atcttttcag tagattcagt
     7501 ttctgataaa ggaacatcta gttttttatc atgataataa gcttcaaatc catctggaac
     7561 cggaaaaaaa tgtattgggt aattcttttc tgaggttgtt gtactagttt ccgtacttgt
     7621 agaacttgtg tcagaagtgg tacacccgct tatagttccg atgagtaaag cgcaagttag
     7681 aatgattgca aatttcttca aaaaaattcc tccttaaaat tgaatatgga ctaatactag
     7741 tcccattgta gcataccgaa tctttaagat taataagaaa aaggactaat tttagtccaa
     7801 aaggtgtgct attcttgaaa gaggaaaaaa ttattgataa agaaaatgta atcggtagca
     7861 atattagacg agtccgatta gaaaaaggaa ttggtcaaac cgagctgatt agagacctac
     7921 agcttcgtaa aattgctata actagggaaa cgttggttaa gattgaaggt ggccgccaac
     7981 acattaagtt ggatcaattg aaagccatca aagatattct acaggtgtct tatgaagatt
     8041 tgcttcaatg actacttgta gtcatttcgt ttgaaattat tatgttacac ccttatgtgt
     8101 cacgaagaaa tactggtata ataatgaatg ggatatgtaa cgatagggta tactgttatg
     8161 ttgcctaata aattgtggat caaaatacaa gaatggaggg atatccttgt ataaggcata
     8221 tgaattggat tttacaaatg ctgacttaaa tgcattctcc tcaagctcgc aatcatatac
     8281 acatgtagta aatcaaatag atcacaacca aaaatctatt aacaagagaa tagaaaatct
     8341 atttgaaagt gaaaatgatt tagttgatta ttattctaag gacagcaaaa ttctagatgc
     8401 agacgaaatt attaaagatt ggtttccaac tataaaagca gatattttta tatctcactc
     8461 tcatgctgat gaaaaattag ctatacgttt tgcatcatgg ctatttgaaa attttggtct
     8521 tactgcattt attgattctt cggtttgggg atacagttct gatttattaa aaaaaataga
     8581 ccaaaaatat tgctataagg aacaaacaaa aacatatgat tatgataaaa gaaatgtaac
     8641 aactagtcat gttcatatga tgctttctac agctttaaat aatatgattg atagtacaga
     8701 atgtctgttt tttcttaata cacctaattc aattagtttg agcaatgaaa tcactaatga
     8761 acagaaattt acgtattcgc catggctata tagcgaactg acgacagctt caatagtgga
     8821 aaaaaagaat ccacgattgg aaagtaatcc tcaaatgagc accgaggatg ttagaagcat
     8881 tataaagcac tattcttcgc aagaaaatct gcaaataaaa tattctttaa atttaagtga
     8941 attaacttat ttacgaaaag ctgatttgaa aaaatgggct ttagatgctg tggaatgcac
     9001 taaaggaagt aatacattag atattttata taaaaacacc attttcacta atctctaatc
     9061 aatttactga atcgaaagga accgggtaga atggataaga aagttttaat aaagaggttc
     9121 tctgaagcta ttgaaaaagg aaatgcagca atatttgcag gtgcaggatt atcgatgtca
     9181 caaggatatg taagttggcc ggaactactt aatgatcctg caacagaaat cgggttggat
     9241 tctaaaaaag aaacagactt agttactctg gctcaatatt ataaaaatga aaatggtgga
     9301 tcaagaggaa ttttgaatca gatacttatg gataattttg gtgaagaatt agaaatatct
     9361 gaaaatcatc gaatactagc aagtttacct attgaaactt attggacaac taattatgat
     9421 catctaatag aaaaatcaat ccgagaagct tataaaaacc ctcaggttaa gaaaaattat
     9481 actcagttag caacaactaa tccaaatgtg gatacaattg tttataaaat gcatggtgat
     9541 atagatgatg tcagttcgac agtaataaca agagatgatt atgaaaaata tgatgattcg
     9601 tacgcgttat ttaaagaaac tttaaaagga gatttgttaa caaaaacttt tctcttttta
     9661 ggatttagtt ttacagaccc taatttagaa agaattttat cagatataag atgggttttg
     9721 agagaaaacc aaagacctca ttattgtata atgagaaaaa tattatagaa aaaattttag
     9781 gttatcgctg aaagccccgg aaatacgggc atttcgcagg atatgagaac tcaatttact
     9841 accaatttac tactttcgga ttgagccgca tatatgctga accatactgc taatacccgc
     9901 caccccaaat acggcacatc ataaattgaa tacgacaccg taaacgcggc gttcctcttt
     9961 cccgtcatgg gagaacagga cgccgctttt ttatgcccaa atagagaaag gaggcgacgc
    10021 catgctattt acttccggcc ctgaccgggc gtttgaacgg ctgatgcagg aaaagcccgg
    10081 tttcgatcac tacgacggcg gcggggcgga cgcgccggag gattgcggca cctgccgatt
    10141 ttaccgcccg gattggaaat atcaattctg ccagtttgca gagtgtccct atcagccggg
    10201 caagctgacc gactatgcag cggtcaaatt cacagtgaaa ggagcgaaca acgctatggc
    10261 agttttccgt gtggaaaaga acaaaggcta tacggtgatg tcaaatcacc acctgcggaa
    10321 taagaacctg accttaaagg ccaagggcct gctgtcgcag atgttgtcct tgccggagga
    10381 ttgggactat accctaaaag gactgtccta tatcaaccgg gaaagcatcg acgcgatcag
    10441 gacagcggta tgggagcttg aaaaagctgg atatatccgg cgtgagcagg gccgtgacgc
    10501 aaaaggcaaa atggccgata tggtctatac catctacgaa cagccggtat tggaaaaccc
    10561 ggtattggaa aatccaacat cggataaccc ggtgttggaa aatccgacat cggataatcc
    10621 ggcgtcggaa aatccaacgc aattaaataa agaagtacaa agaactgact tatcaaaaaa
    10681 agaaaaaata attacagatg gacaaagtac ccattccatt cctatcccat ccccgacccc
    10741 tgcccctatg gagggcgagg cagcggctac gccgccggaa cggaaaagga caggaaagga
    10801 tgaggctgta cggatttatc gggaaatcat tttggagaac atcgagtatg cctatctcat
    10861 tcaggacagg agcattgacc gtgaacagct tgacgaaatc gtagacctga tgctggaaac
    10921 cgtctgcacc gcccgaaaga caatccgtgt cgccggggac gactaccctg ccgagctggt
    10981 gaaatccaag tacatgaagc tgaccggcga acatatccgc tttgtccttg actgtctgcg
    11041 ggagaacaca acgaaagtcc gcaatatcaa acaatacctg cgggctatgc tgttcaacgc
    11101 ccccagcacc atttccaact actacacggc ccttgtcgcg cacgacatgg cacagcccga
    11161 ttggggaaag cctaaatccg gcctgccgga ctattcctgc ggcgagggcg aaagcctgta
    11221 acgagaaaag gaggacgacc ctatgaagca gggcgcattg atttttgacg agcgaacaga
    11281 ccgttacgac atccgctttg atctggccga ctattacggc ggcctgcatt gcggggagtg
    11341 tttcgacgtg atgatcggcg gcaaatggag gcccacccgc attgaaatgg ccgaaaactg
    11401 gtatcttgtc ggcatccggg ccgacgacct ttccggcctg cgggtgcgga tttgacctat
    11461 atctacctgc ggcgtctggt ggttccgcct tagacgccgc ttttgacttt ctgacaagga
    11521 gggatgcgat tgcaggaaga agttactcaa aagaccattg ccctgtccat gaaaacgggc
    11581 aagctcacgg ctcaagtgct gcaagcggcg ctgaaaaagt acctgcaaca ccgggccaag
    11641 ggcaaaaaca cgctgcacca cggccagcag agcctaaagc agcttaaaaa gcatggggct
    11701 gatctctcca acattgagat caccgaggcc aacattggag cgttcaagcc atgcgccaag
    11761 aaatacggcg tggattttac cttacgaaaa gataagacca cccagccgcc ccactacgtt
    11821 gtgattttca aggccaagga tgcagataac cttgatctgg cgtttcggga gtttaccgcc
    11881 aagacgcttt ccaaggagca gcggccctct atccgcaagg ttttgtccgc tgtgaagcaa
    11941 aaggcggcgg cccagaccaa gcagcgggcc aaggagaaaa tcaaggaaag ggggctggaa
    12001 ctgtgaagcc tgacgtaaag aaattgctga tcctgaacct cccgtatctg atttttgtgt
    12061 acctgtttgc gaaatgcggg gaggcgtacc ggctggccgc tggtgctgac ctgtcgggga
    12121 agctcctgca ttttgcggat ggttttgcgg cggcttttgc caacccgctg ccaagcctgc
    12181 acctgtttga cctgtgtatc ggtatcgccg gtgccgtgat cgtgcggctg gtggtgtact
    12241 gcaagagcaa gaacgtgaag aaataccgca aaggcatgga gtatggcagc gcccgctggg
    12301 ggacggccaa agacatagcg ccttacatcg accccaagtt tgaaaataat atcctgctca
    12361 cccaaacgga acggcttacc atgaccggca ggcccaaaga ccccaagaca gcgcggaata
    12421 aaaacgtgct ggtgatcggt ggcagcggtt cagggaaaac gagatttttc gtgaaaccca
    12481 acctgatgca atgctttccg accacggact atccgacttc gtttgtggtg acagatccga
    12541 aaggcacttt ggttctggaa accggcagga tgttccagca ggcgggctac cgcattaaaa
    12601 tcctgaatac cattaacttt tccaagtcca tgaagtacaa cccctttgtc tacatccatt
    12661 cggaaaagga cgtgctaaag ctggtaaata ccctgatttc caacaccaag ggcgaggggg
    12721 aaaagtcagc ggaggatttt tgggtgaagt cggaacggtt gttttattcg gccctgatcg
    12781 gctatatctg gtacgaggcc ccagcggagg aaatgaactt ctcaacgctg ctggaaatga
    12841 taaacgccag tgaagcccgc gaggacgacc cggagtttca aagccccgtc gatctcatgt
    12901 ttgagcgttt ggagcagaaa gaccccgacc attttgcggt gcgccagtac aagaaattcc
    12961 tgctgtccgc aggcaagacc cgttcttcca tcctgatttc atgcggtgcc agacttgcgc
    13021 cctttgacat ccgggaggta cgcgagctga tggaggacga cgaaatggag ctggacacca
    13081 tcggggacga aaagacggtg ctgtatctca ttatgagcga tacggacacg acctttaatt
    13141 tcattctggc tatgctccaa agccagctaa tcaacctgct ttgtgaccgg gctgatgatg
    13201 tgtacggcgg gcggctgcct gtccatgtac gcctgatttt ggatgaattt gccaacattg
    13261 gccaaatacc caatttcgat aaactcattg ccaccattcg aagccgtgaa atatcggcct
    13321 ctattatttt gcagagccag tcgcagctaa aagcgattta caaggacgcc gccgagatca
    13381 tttcggataa ctgcgatagt gtgcttttcc ttagtgggcg cggcaaaaat gccaaggaga
    13441 tttccgatgc gctggggaaa gaaacgattg acagtttcaa caccagcgag aaccggggaa
    13501 gccaaacgtc ccacggattg aactatcaaa aattaggaaa ggagttgatg tcccaagacg
    13561 aaattgccgt gatggacggc ggcaagtgta tcttgcagct acggggtgtg cgcccgtttt
    13621 tatcggagaa attcgatatt accaagcatc cccggtacaa ataccttgcc gacgccgaca
    13681 agaagaatac ctttgacgtg gacagatttt tgactatcac gcgccggaaa cggcagcaag
    13741 tggtaacgca ggatgaagta ttcgacctgt atgaaatcga cctgtcggac gaggacgccg
    13801 ccgctgaata aacagcggct tttttcattc caacaacaaa atcaaaaaat cattatgagc
    13861 cggaaaccgg cagaaagagg taaatttatg gcatttttta attccgcagt tactactttg
    13921 cagactatcg tgatcggact gggcggcgct ctgtgcgtat ggggcggcat caatctgttg
    13981 gagggatacg ggcaggacaa tccgggggca aaatcgcagg gtgtcaagca gcttgtcgct
    14041 ggcggcggcg tggccctgat cggtgtcact ctggttcccc tgctgtccgg gctgctgggc
    14101 tgatcctggc ctttgtccct gtccaaaccc ttaactaatc gcctccgcgt cctcccggcc
    14161 agaccgggag ggcgcgggaa aggaggtgct acccgtgatt agtgaaatca ttgaagaatg
    14221 gataaaaggc atcctcatgg acggtatcac gggcaacctg tccgggctgt tcgatacggt
    14281 aaatgccaaa gtcggagaaa tcgccgccga cgtgggacga accccgcagg catggaacag
    14341 cggtattttc aatatgctgc acagcctgtc ggaaaccgtg atcgtcccca tagccggggc
    14401 catactcgcc cttgtcatgt gctatgagct tatccagatg ataacggaaa agaacaatat
    14461 gcacgacttt gacagctcca tgttcttccg ctggatattc aaatccgcgt ttgcaatcct
    14521 gatcgtaacg aacacatgga acatcgtcat gggcgtattc gacgccaccc aaagcgtcgt
    14581 caatcaaagc gccggtgtga ttatcgggca gacatccatt gattttaaca ccctgatacc
    14641 agaccttgaa agccaattgg aggctatgag cgtgggcgct cttttggggc tgtggttcca
    14701 aacccttgtt gtgggcctca ccatgaatat cctttccatc tgcattttcc ttgtgaccta
    14761 tggccgcatg gtggaaatct atgttgtcac gtcgctgggg cctatccccc ttgccacaat
    14821 gggcaacgcg gaatggcgcg gcatgggcca agggtatctg aaatccctgc tggcgctggg
    14881 cttccaagcc tttttaatca tggttgtggt gggtatctac gcggtgctga tacagaatat
    14941 cggttccgct tccgacatat ccggcgcaat ctggggctgt atgggctata cggtgctgct
    15001 gtgcttctgc ctgttcaaga ccggcagtat atcaaaggcc gtattcgggg cgcattgatc
    15061 ccaaaatcca agcatacaca ggaggaactt gtttatttca acgtacaaca tcatttacgc
    15121 tgacccgccg tggcggtatg actgcaaaaa cgtacagggc gcagcggaaa atcactattc
    15181 caccatgagc attgacgagc tgtgcgccct gccggtggaa cggctggcgt ccaaagactg
    15241 cctgctgttt ttgtgggcca cattccccat gctgccggaa gctctgcggt taatcaaagc
    15301 gtggggcttt tcattcaaga ccgtggcttt tgtatggctg aaacagaacc gtaaaagcct
    15361 tacatggttt tacgggctgg gccgctggac aaggggaaac gcggaaatct gcctgctggc
    15421 aacacacggc aagccgaagc gtcgttctgc ctctgtccat cagtttatta tcagcccgat
    15481 tgaacaacac agcaaaaagc cggatgtgac ccgtgaaaaa atcgtagagc tggcgggcga
    15541 tttgccccgc gtggagctgt ttgccagaca gaaaaccccc ggctgggacg tgtgggggaa
    15601 cgaggtggaa tgtgacctta tcctgacgtg aaaggaggtg ccaaatggct tatgtaaccg
    15661 tccccaagga cttaacccat gtgaaaagca aggttgtgtt tgggcttacc aaacggcaac
    15721 tgatctgttt ttccggggcg ctggtgatcg gcgtcccctt atattttctc acccgtgact
    15781 atcttaccaa cagcgcggcg gccctgctca tggtatttgc catgctgccg ggctttttgc
    15841 ttgccatgta cgagcgtcac ggccagcccc ttgaagtggt gattatgcag atcatccagt
    15901 gctgcttcat ccagccaaag gagcgtccct atcagaccga caacacctac accgcccttg
    15961 tgcggcaata ccagatggaa caggaggtaa aggccattgt ccaaaaagga aatcccaaga
    16021 gaaaccgaaa aaacaaagct gacccgcgcc cagcgaaaag aaattgacgc ggtaatccgt
    16081 aaatataagg gcgacggcag gccccacacg gcgcagcaga gcatccccta cgaggtcatg
    16141 tacccggacg gcgtgtgccg ggtatcgccc ggcgtctttt ccaagtgcat tgagtttgcg
    16201 gacatcagct atcagcttgc ccagccggac acgcagacgg ctatctttga aaaactgtgc
    16261 gacctgtata actatgtgga cgcctccatt catatccagt tttctttcct caatcggaaa
    16321 gttgacccgg tgcagtacgc caagagcttt gagatcgcgc cgcaggggga cgacttcgac
    16381 gacatccggg ccgagtacac cggcattctg caaaagcagc ttgcaaacgg caacaacggc
    16441 atggtaaaga ccaaatacct gacattcacc atcgaggccg aaagcgtgaa agcggcgcga
    16501 gccagattga agcgcatcgg ctttgacctg ttaggctatt tcaagagcat gggggccgta
    16561 gcccatgtga tggacggctg ggaacggctg aacctgctgc atggcgtgta ccacccggac
    16621 ggcgagatat tcaattttga ctggaagtgg ctggccccgt ccggcctctc caccaaggat
    16681 tttattgccc cgtcctccct gtgcttcggc aatgcaaaga cattcggcat gggcggcaaa
    16741 tacggcgcgg taagtttcct gcaaatcctg tccccggagc tgtcggacga tatgctggcc
    16801 gacttcctca atacggaaag cggtgtttta gtcaatctcc atgtgcaggc cattgaacag
    16861 accaaggcga tcaagaccat caagcgcaaa attaccgacc ttgacgctat gaagattgcg
    16921 gagcagaaaa aggccgtccg cagcggttac gatatggaca ttcttcccag cgaccttgcc
    16981 acctacggcg aggacgccaa gaagctgctg acaaagttgc agacccgcaa tgaacggctg
    17041 ttccagttga cgttccttgt cctcaacgtg gccgacacca agcaaaagct gaataacgac
    17101 gtgttccaag ccgcaggcgt ggcccaaaag cataactgtc cccttgtccg gctggactac
    17161 cagcaggaac agggccttgc aagcagcctg ccgctgggcg tcaatcagat caagatacag
    17221 cgcagcctta cgacttccag cgtggccgtg ttcgtcccct ttgtgacgca ggagcttttt
    17281 cagggcggcg cggccatgta ttacggcatc aacgccaagt cccgcaacat gattatgctg
    17341 gacaggaagc aggcccgttg ccccaatgcc ttgaagctcg gcacccccgg cagcggcaaa
    17401 tccatgagct gtaaatccga gatcgtcagt gtgttcttaa cgacgcctga cgatattttt
    17461 atttcagacc cggaggccga atattacccc cttgtcaaac ggctccacgg acaggtaatc
    17521 cggctgtcgc ctaccagcaa ggactttgtg aacccgctgg acatcaacct gaattattcg
    17581 gaggacgata acccgctggc cctgaaatcc gactttgtgc tgtcgttctg tgagcttgtc
    17641 atgggcggca agaacgggct ggaagccatt gaaaagaccg tgatagaccg ggctgtgcgc
    17701 gtgatctacc ggccctatct ggcagacccc cgcccggaga atatgccgat cctgtccgac
    17761 ctccacaaag cgttgttaga tcagcatgtc ccggaggctg accgggtggc gcaggccctt
    17821 gacctgtatg tgtccggctc cctgaacgta tttaaccacc gtaccaacgt ggacatcggc
    17881 aaccggcttg tgtcctttga cattaaggag ctgggcaagc agctcaaaaa gctggggatg
    17941 ctcattgtcc aagaccagat atgggggcgc gtcacggcca accgaagcca aggaaaggcc
    18001 acatggtatt ttgccgacga gttccatttg cttttgaaag aggaacagac ggcggcctat
    18061 tctgcggaga tttggaagcg gtttaggaaa tggggcggca ttccaacagg tgccacccag
    18121 aacgtcaaag acctgctttc ctccccggaa attgaaaata tccttgaaaa cagcgacttc
    18181 attacgctgc tcaatcaggc gtccggggat agaaaaatcc ttgcggaacg cttgaatttg
    18241 tccaccgaac agcagaagta catcgacaat tccgaacccg gcgagggcct tttgatcttt
    18301 gaaaacgtgg tgctgccctt taccaacccc atcccgcaca acacccagct ttacaagatt
    18361 atgacgaccc gcttaaacga ggtggcggga gtatgacccg gcgacgccac aaaggaggtg
    18421 aaccaccatg aaagagctga aagccaaggc gaaagtgacg caggccatga cccgcgacgg
    18481 gctgacgctg gaaaatcagg ccaccggcga ggtggagaac atttccagcc gggaggccga
    18541 acaggatttg tccgcgccgg ggccgggcgg caccgccgat aagctgctgg aacgggccga
    18601 cgccatccat gacggccata aggccaagaa agccgcgaag caggccgggg ctgtggccgc
    18661 cgagggggac gctgccctgc accggccatc cgcccggctc caactgtcgg aggaagaacg
    18721 ggccgacccg gatttacagc cctatatccg aaaatcggac aaacgggccg ataagctgga
    18781 taaggcccgc gccgccatcc ccaagaagcg cgtcccggtc aaggaaaccg tctttgacga
    18841 ggcaagcggc aaagcaaaga ccgtcctgca ctttgacaaa caggacaagg ggcctccctc
    18901 cctgaaaccc aatccggcag gccgtcctgt ttccgaggtt tttctattcg gccacgggaa
    18961 aatccatgaa gtcgagcatg aaaacgtggg tgtggagggc ggccataagg gggaggaact
    19021 tgccgagcgg caggccggaa aagccatccg cagcaccatc cggcaccaca ggctgaaacc
    19081 ctactgggac gcggaaaagg ccgagcgcag gctattgtct gccaacgcgg agtatttcta
    19141 ccagaaatct ttgcgggata acccggagat cgcacaggcg gccagcaacc ccatttcccg
    19201 gttctggcag aaacagcaga tcaagcgcca gtacgccaag gccgcccgga cagcgggcca
    19261 gaccgcaggc gcggcggcac agggcgcggc caagacagcc ggggcctcca cgaaagcggc
    19321 caaggccgca gccaaagaaa gtgaacgggc ggcctccttt gtggcccgcc actggaaagg
    19381 ggcgctggcc gtccttgtgt tggggctttt gatgctgctt atcatcggcg gcttacagtc
    19441 ctgcaccgcc atgttcggca gcgccggaag cggcatcacg gcgtcctctt acttttccga
    19501 ggatagcgat atgttggccg ccgaggacgc ctacgcggag ctggaagccg agctgcaaga
    19561 ctatctggac aactacgagg ccacccatga ctatgacgaa taccattttg accttgacga
    19621 gatcagccat gacccctatg tgctgatttc cattctgtcg gcgctccatg acgggatatt
    19681 taccatcggg gaggtacagg gtgatttgtc catgctcttt gacaagcaat atatcctgac
    19741 agaaaacgtc gtggtagaaa cccgttaccg caccgaaacc gatacatgga cggacgcgga
    19801 gggcaacacc catacagaca cctaccaagt gccgtatgac tattacatct gctacgtcac
    19861 gctggaaaac ttcgacctgt cccatgtgcc agtctatatc atggacgagg aaacgctaag
    19921 tttctattcc ctgtatatgt ccacgctagg aaaccggcct gatctgtttt ccggcagcca
    19981 gtaccccaac gcctccaccc tgacgccgcc gacctactac gacgtacccc cggaggcttt
    20041 ggaggatgcc acctttgccg ccatgctcaa agaggcggaa aaatatatcg gttatcccta
    20101 tgtgtggggc ggcagctctc ccagcaccag ctttgattgc agcggcttca tttcgtgggt
    20161 aatcaatcat agtggatgga acgtgggacg gctgggggcg cagggcctat ataacatctg
    20221 cacccctgtt tccagttcgc aggccaagcc cggcgacctt gtatttttca agggaaccta
    20281 cgacaccccc ggcgtgtccc acgtcggcct gtatgtgggc aacaatgtga tgctgcattg
    20341 cgggaacccg atttcctaca cgaaccttac ttcaaactac tggcaatccc atttttacag
    20401 ttacgggcgt ttaccttaac gccagaaagg agctttcaat tatggcaacc aaacttgacc
    20461 gcatcgaaaa ggacatccag aaaaccaagt ctaagatcgc ggagtttcag aaacagcttc
    20521 gggagctgga aacgcagaaa accgaacagg agaatttgca gatcatccag cttgtgcgcg
    20581 gcatgaacat gaagccggag gaatttgccg cgttcttacg cagcggcgca atgcaggccg
    20641 cccctgccgc aaccccttac catgaacagg aggacaatgc ccatgaagaa taagaccaga
    20701 cggatttccc gtattctccc cgcacttctg gccgtgatgc tctgcgtcac ggcctttccc
    20761 gttaccgccc ttgcaggcgg caatgacccg gcaccggccc cgctgccgga ggctacaacc
    20821 gaacccgcta cgggcggttt ggagcctgaa acagacgaaa ccggcaccgc cacggacggg
    20881 acagaaaccg aggccgaaaa agataccggc cctctgaccg gcaaggacat caccgacctg
    20941 ttttccgcgc tgttcggttc caaggtgagc attgccgcca cggacgacgg catccagatc
    21001 accaccggca ccgacaaaaa agaacctgaa cagaccggca ccgtcaccac caacggcggc
    21061 aggctgaatg tccgcaccgg cgcggggctt gacaagaccg cgttcaccca gcttcccaat
    21121 gggacgacgg ttgaggtagt cggcacagac ggcgactgga ttaaaattct cttgccggag
    21181 cgcatcggct atgtccattc cgactatatg accgtcagcg aaaaggaagt agcggctacc
    21241 ggcgagggcg gtttttccct ctccattgac ccggaggaaa ttgcttctct gctggaactg
    21301 ttcaatggcg gcggggccag cgccgccctg tccccggacg ggaacctgtc actgattgac
    21361 gacatcggca gcgccgcgaa aaatggcaag cagtttatca ccgtggaaac caaaaacggc
    21421 aatgtgtttt atctgattat tgaccgggac gacgagggaa aagaaactgt ccatttctta
    21481 aatcaggtgg atgaagccga tctgctgacg ctgatggagg acggggaaac cgtcaccccc
    21541 gctgctgtct gctcctgtac cacgaaatgc aaggccgggg ctgtgaacac gaattgcccg
    21601 gtatgtaaaa ccaacctgac cgagtgcagc ggcccggagc cgcaggaacc ccagccggag
    21661 gaacccgaag ccccggagga agaacccaag ggcggcgcgg gcggcctgat cgtgttcctg
    21721 ctggtggcgc tggcgggcgg cggtgcggcc ctttactatt tcaagttcaa aaagcccaag
    21781 gctgaaacca ccggcagcga cgatttgggc gagtatgatt ttggggagga cgaggatttg
    21841 gaggacgagg aacccgaaac cgagtttgac ccggaagctg attttgtgag tgaacaggag
    21901 gacgaggaat gacatataaa cttgtaatcg cggaaaaacc cagcgtggcc cgcagcattg
    21961 cgggcgtgat cggggccacg gagaaacacg acggctattt ggaggggaac ggctatctgg
    22021 tgagctggtg catcggacat ctggtgtcct ttgccgacgc cggacgctat gacgagcgtt
    22081 tcaaaaaatg gcgctatgag gatttgccca ttctcccgga aacatggcag tacatcgtcc
    22141 ccgacgacaa gaaacagcag tttgacgttc tctgttcgct gatgcagcgc cccgacgtga
    22201 ccggccttgt gtgcgccacc gacgccgggc gcgaggggga attgattttc cgtttcgtct
    22261 accagatggc gggatgccaa aagccctttg agcgcctttg gatttcctct atggaggaca
    22321 gtgctattaa ggacggcttt gcccacctga aaccgggcgg cgactatgat ccgctgtatc
    22381 aatcggccct gtgccgggcc aaggccgact ggctgatcgg cattaacgcc acccggcttt
    22441 tttccgtcct gtaccacaag aacctgactg tgggccgcgt ccagacgccg accttaaaaa
    22501 tgctggtgga cagggacgcc aagattaccg atttcaagaa agagaaatat cacatcgtcc
    22561 atatcacggc gggcggcgcg gacgcggtaa gcagccgctt ttccgacgct gccgaggcaa
    22621 acaccgtcaa ggcggcttgt gcaaaagcgc aggccgtttg cgtttccgtg acgcgggaga
    22681 aaaagacgga acagccgccc aagctctatg accttaccac cttgcagcgg gaggctaacc
    22741 ggcttttcgg ctataccgcc aagcagaccc ttgactatgc ccaggcactg tatctaaaga
    22801 agctgctgac ctatccgaga acggatagtc aatatcttac cgacgatatg ctgcccgccg
    22861 tggaaagcct tgtgtccggc ctgtgggagc tggtgccgtt tgccaagggc ctgaaccttt
    22921 ccccgcagtt tgaccgcatc ctgaacagca aaaaggtgtc cgaccaccac gccattatcc
    22981 ccaccgctga atttgtgaag cagggctttg gcactctggc cgagagtgaa aaaaagctgc
    23041 tgtccctgat ctgctgcaag ctcttatgtg ccgtggccgg gccgcatatc tatgaggccg
    23101 tcaccgccac atttacctgt gccgggcagg agtttaccgc caagggcaag accgtccttt
    23161 cccccggctg gaaagagatt gaacgccggt tccgttcttc cttaaagacc gacgccgacg
    23221 aggacgccga ggcggtgcgg gagctgccgg agctttgcga gggccagacc tttgcagacg
    23281 tggccgcctc tgtcaccgag catttcacca cgccgcccaa gccctacacc gaagatacgc
    23341 ttttgtccgc tatggaacgg gccggggccg aggatatgcc ggaggatgcc gagcgcaagg
    23401 gattaggcac accggccacc cgcgccgcca ttctggaaaa gctggtgcag atgggctttg
    23461 tccagagaaa aggcaagcag ctcattccca ccaaggacgg catcaatctg gctgtggtgc
    23521 tgccggaggc gcttacttct ccccagctta ctgccgaatg ggaaaaccgg ctgaccgaga
    23581 tcgccaaggg gcaggccgat cctgacgaat ttatggacgg catcgagacg caggcgcggg
    23641 agctggtgca gacctattcc tgtatcagtg aggaaaagca gaaattgttt caggccgagc
    23701 gtgttcctat cgggacgtgt ccccgctgtg gtgaggctgt ctatgagggc aagaaaaact
    23761 actactgcgg aaaccgggcc tgccagttcg tcatgtggaa gaatgaccga ttttttgagg
    23821 aacgcaagaa agcgttcacc ccgaagatcg ccgctgcgct gctcaaaacc ggcaaagtca
    23881 aggtaaaggg cctctattcc gtaaagaccg gcaaaaccta cgacgggacg gtgcttttgg
    23941 ctgataccgg gggcaagtac gtcaactacc gcattgaaca caggagctaa aggacagtaa
    24001 cacagcaagc atagggagtg tggctacact cccggtaaaa tcccccggcc gcgtccctgc
    24061 cgggccgggg atttttgctt gttggggaag tccccaaccc cctatttttt gaaacagaac
    24121 agagaaagga gtgaccgcgt gaacgaagta ttttctatcc aagtccataa ccggcagttt
    24181 ttggaacagg gcaaacaagg cgtctggctg gatttgccca ccacaaccga aacgctgcaa
    24241 gccgccctgc gggatgttgg cattactgcc gacaatccgc aggatttttt tatcaacggg
    24301 tattcctgcc cggaggacag acaccttgcc attccctatg acatggtgct ggccgccgac
    24361 gtggacgagc tgaatttcct tgccgcccgg ctgggccagc ttgacgccgc cgagatcgca
    24421 gagctgaacg ccgccctgca aaatccccgt ggcggctttg agaatatcgg ccagatcatc
    24481 gactacaccg aaaatgtgga ttactatgtg catcttcccg acgttagggg ggatggacag
    24541 ttgggcgact actacctgaa ccgttccggc atggtggata tgccggagga atggaaagcc
    24601 gggattgata cggcgcagtt tggacgccac attgcccagc aggaacaagg cgtttttacc
    24661 cagtacggct atctggtgag aagcggcgac gaatggcagc gcgtccatga gggccagccg
    24721 gtgccggagg aataccgggt gatgcactac ccccagccgg aagctgaccg ggaggaaccg
    24781 caggcccagc agccggaggc atccgaaagc cccgacaaag cgccgccccc ggttatcccg
    24841 atcatgctgg acggcatgaa cagcaaagaa cgcatgaaag tgattactga ccgtctggaa
    24901 accggcgtac aggagctttt tgaaagtagc cgctatatgg cttacttatc cgctatgtcc
    24961 aagatgcacg attacagtct gaacaatacg ctgctgatcg ccatgcaggg cggttcgatt
    25021 gtggcgggct ataacaggtg gcaggatgaa tttgaccgcc atgtgaagcg gggcgagaaa
    25081 ggcattaaga tactggcccc ggccccgttc aaggttaagc agcagatgga gaaaaccgac
    25141 ccggccaccc agcagcccgt gatcggcgcg gacggcaagc ccgtgaccga agaacaggaa
    25201 gtgacggttc cggcctttaa ggtggtgaca gtctttgaca tcagccagac cgagggcaag
    25261 gattttccca tgccctatat cagtgaactt accggcgacg tgcagcagta tcaggatttc
    25321 tttgccgcgc tggaacggac atcaccctat cccataagca ttgagccgat ttcagacggg
    25381 gccaagggcc gctgcttcta cgcaaaacag cgcattgcca tcaacgaggg catgagcgaa
    25441 ttgcagaccc taaagaccgc catccatgag attgcccatg ccaagctcca cgccattgac
    25501 cgggaggccc ccgccgagga acaggcggcc cggccagacc gcagcacccg cgaggtacag
    25561 gccgaaagcg tggcctatac cgtctgccag tattacgggc tggacacgtc ggactattct
    25621 tttggctatg tggccgattg gagcagcggc agggagttat ccgagctgaa agcctccctt
    25681 gaaaccatcc gggccacggc cagcgaattg ataaccgaga tcgacggcca ttttgcccag
    25741 cttcagcagg agcgcgaggc ccggcaggaa caggaggccg tcacggttga cgttaccccg
    25801 gaggcagcgg ccccggcgca ggccgaggaa gaacaggccc cggcccttga tccggcagcc
    25861 gagccgcttg tgactgtgct atggagcgaa agcccccagc taaaggacgg ccagcaaatg
    25921 ccgttgcatg aggccgacgc gctgtttgcc cgtctggatg cagcatatcc ggcagaggca
    25981 ggctatgaca aaaccgcgtt ccgcattgac tgtatctttc agggcgagcc ggacagctac
    26041 gaggggcggc aggattttgg agatagggac ggttccctga tcgaacatat ccagagctac
    26101 caccaatttt acgcgcagga cgaaaactgg aaaaagcatg taatcgctac aaccggcata
    26161 gagggctggg agcaggacaa ggcccatcgg gatatgctgt taggcgagtt tgtcccctat
    26221 atgaagctgc attgcagcct tgcccaaatg gaacagacgg cgcagggccg cttacagtcc
    26281 ggggaaaccc tgacgccgga ggaaacggcc tatttggggg cgcttctctc ttatgtgcag
    26341 gagtgccgcc ccatgctcaa tcagggccag tatcagttgc cggagccgcc gaaactggct
    26401 gacttcgacc agagcttgca ggactacaaa gcacaggtac aggccgagat cgcgcaggag
    26461 gccgccgcag ccggtatgac cgtggaggaa tacgcggcgg ctggctatga agcaccccaa
    26521 caggacacct tttccatcta ccagcttcga ggcggggagg aaacccgcga ctatcggttt
    26581 gagccatacg agcgtttaca ggccgcaggg ctggccgtgg acagtgccaa ctatgacctt
    26641 gtttatacgg caccgctgga taaaagcacg tctttggagg atatttaccg cacattcaac
    26701 atcgaccacc cggcagattt taggggacac agcctttccg tttccgacgt ggtggtgctg
    26761 caccagaatg gacaggacac cgcccactat gtagacagct tcggctatat ggaagtgccg
    26821 gagtttttgc gggaaaatcc cctgcgtacc gccgaactgt ctacggagca gaacgaaaac
    26881 atgattgacg gcattatcaa caatacgccg cccgaaccgc agccggagga acccgaacag
    26941 ctatcttttg aggatgtggc agttgcttcc ggccagacac aggaggaacc cccggaggct
    27001 gcgcccccgc aaacggctgt ccgctattat cccatcaatg agggagccgc ccgccgcgcc
    27061 aaggaagcca tgagcttttc tgactaccgg cccggcagcg ccacggcgga ataccggcac
    27121 tatgtcgatc aggccgtgga aattgcggag cgccagaaaa agcgtgtgga gccagagtat
    27181 cacgaaaaga tagacagcct ccttgacacc tacgcccgca agctggccga gaacatgaat
    27241 aagggctatg agattaccgc ccgcgtcccc tctgtcctga ttgccgggcc gtccaatttc
    27301 ccggtacggg cgaaagaaaa gcagaacgcc gccagtgacc gcaacatgga ggaatttcag
    27361 tacattcagg gcttgcttga caaaatccgc agcaccggca tgggtggtat cagcgccgac
    27421 gatccgcagg ccgtttccaa gctggaaaag aaactggaaa agctggaagc gtcgcaggag
    27481 ttgatgaagg ccgtcaatgc ctactaccgc aagcatggga cgctggacgg atgcccccat
    27541 ctgatcgaaa gaggcattga aaacctgaaa gcggatatgg cgtcgggctg gcactatgag
    27601 aaaaaaccgt tccagtcctg gcagctctcc aacaataacg ccgagatacg ccggttaaag
    27661 ggccgcattg aggaattgac ccgccaaaag gaggcggcct atgtgggatg ggagtttgac
    27721 ggcggcactg tggagatcaa ccgggtggcc aaccgcctgc aaatcttctt tgaggggaag
    27781 ccggatgctg ctgtacgcga cgagctgaaa agcaacggtt tccgctggtc gcccaaggcc
    27841 ggggcatggc agcggcagtt aaacgacacc acaatccgcg tcgctgaccg tatcaagtgc
    27901 atccagcccc tttccggcga aaagcccagc gccttacagc ttgcggcccg cagggagaaa
    27961 gaaaagccct ctatccgggc gcagctcaac gcggccaaga ccgaacaggc caagcagcca
    28021 ccggcgcggg aaaaatcaaa gggattggag gtagagtaaa tgcagaagtt tgaaaatgtg
    28081 gacgttctgg ccgcgctgga acagatcatg cggcagaaca ccgcgtttta tcaaagtgac
    28141 tttggcattg acaaagacat tatcaggcgg gatgccgcca gcgatcaggc cgcagacaag
    28201 accctgctct ggatgtcccg gccctccggg acgtactgtt tccgggaacg tgatgttttc
    28261 ctgaaagaca cccgacagta caacacatgg aaattttacg gggagcagac ccgtgacaag
    28321 atactggcct acgcggtgga gctgaccggc acacagggcg gcactatccg gggcaatctc
    28381 tatgagctgg actatccgca gcatttccgg cacgtcattg aaaccgccca gccggtgagt
    28441 gtgaaccggc tcttttatga gcatggcacc cgtgacatcc cggagagcca gcgttttgac
    28501 ggaagccctg accgggtatt gggaaacttt ttgtactatg aggcccagcc ccatgacccg
    28561 gctgtgctgc aggaggcgct acggacggag cagcacagcc gggggcgggc cgtccccggc
    28621 gatttcaaag tccacgtcac cgctttgcat gacagccgga ttgaaaccga ggcccggcgt
    28681 attgtggaca gcctgaaaga tctgtccgcg cctaacagcc ccaataaaac gcatttcatg
    28741 gtggagatct ccccgcactt tgcggcgatt gcttccacca aggataatga ccggctcttt
    28801 gccatgctgc cctataaatc cctgtgtttt accgggatga aaggcaggca tggcgtgtat
    28861 gccgtgatta accgggacga gcgccgggat gtgagtattc gcaggccccg gccctctatc
    28921 cgcaagcagc tatccgacag caaacaggcc gccagcccaa aaaaggcggc ggccagaacc
    28981 aaaaagaatg aattggaggt ataaggaatg atgcacttta ccgtggagga agaaaacctg
    29041 atctgtatgt accacaatgc agaccggcgc agaacgataa acaggctcac cgccgtcatg
    29101 ccggttatgg atggggatat gcgggcgcag gcccagcaga ccctttccaa gctggaacgc
    29161 atgacggatg ccgactatga cggccagaag ttccacttca cagacgaata acgaacagca
    29221 gacgccgggc gcggcggcca tgtggtcgct tgcgtccggc gtcttttctt tttgcctatt
    29281 cctacgcatt tagaacccgg tattgtcggg gataggatga agtattcgct tgcccctgca
    29341 aacatgcggg agaagccttg cagcgggcgg ttttcaatcc cttaaatgcg taggttgcag
    29401 ctataattag acccctgaaa cagatatagc cgcgcagcgg gtgtatctgt ttcaggggtg
    29461 tgcaggtgat agccgcaaag cggcgtaaga gggtgcagcc ctcttgccgt ctatctctgt
    29521 tccagcggga agctcggcaa tgcttccagc agtttcaggg aaatgcgctg ccgtatatct
    29581 tcgtcaatga ctttcttctt tttgccgttt gcctgtctga tctccaccgt ggaaagctcg
    29641 ttgatgtagt cagcataatg ggccaacact ttttccgtgg cccacctctc accggcaacg
    29701 gcggctttga tcgtttcata gtccagcagc ttttcttgtc cgtccatcct gatacccccg
    29761 tcagactgat tttttctatg ataccatatt cggaagcatg gaaccagaga aaacggcgct
    29821 tttctgctgg taaattctac gcatttagaa cagcacttcg gcggggatag gataaaacac
    29881 ccacataccc cgctgaccat gccggaaaag ccttgaaata taagggcttt tacagctcta
    29941 agtgcgtagg tttccagtat cttttccgct ggcgctcggc ctctttgcgg cggcgcatcc
    30001 gtttggagca ggccgcgcag tatttggccc ggttagactt cggcgtgaac gtggccccgc
    30061 actcacagca gcgtttcact tcgtcccggt ctttggtgat ctcggcatac agggccgcat
    30121 ccagcgggag gacagcggcc ttaaaccagc ggcacagaag cgaataggaa atgctctgta
    30181 cgcaaataca ttcttcgccg tcgtccagca acaggcagtt gccgtcacaa tagttgcagc
    30241 actcatgcgt cagcttccgg gccttgcgat attgagggta attcattcgt ggaatactca
    30301 tagctcttgc gtccattcct ttcccggcgt catacgcaaa atgccgtcca cattctgctt
    30361 gatgatgccg tattcctgca tctgcttttt cgcttcgccg tacttctcat acagccgttc
    30421 cttttcctcg gccaatcgct tgtactcggc tttcagggcg tacagatcgg ggagcttttt
    30481 cacaccctgt ccctttaggg cctttgccgc agcttcatac aaaatcaacg tgctttcatg
    30541 ctcacgccgg aattttgcct tatccgctgc attgcggtat tccatagcca cgggccagag
    30601 ctgcttgtag gtagaaatat tctttatcag caccgccata tccgcaagcc ggtgttccat
    30661 agctttgagg gtagcggcgg cctcgtcgct ggcggcggtg atctcggcca ctttgctttc
    30721 caaatccggg taggtgtcta tcccatgttc agtcaggaaa ttcaaagtct ttgcggcctg
    30781 cttcaaattg tggagcttcg cccacctctc atagcctgcc gactgctggg ccttaatgtt
    30841 gttttccaga tcaatccgca aagaaatccc cttgcgctct ttgggcgctc tggtgataac
    30901 gcggcctttg atacgctctt tgatggcttc ctcggtgtag gcttccccca atgtcttgca
    30961 gcgggtaaag cgttcctgtc cgggagcgcg gaaagaaata aactttcccg gcttgatctc
    31021 atagccctgc gcctgcatga gccgcaggaa atcatcaaaa tcttttgcct gcgggatagc
    31081 ggcgtcaatg gctgctttga gcttcgcttt ccagctcgtc cctttccgct gggcgtccca
    31141 ctcggcatag ctcttgccct tactctggcc gggcttcacc acggacaatc cgttttcctt
    31201 gcacagcctg tcgctggtgc gccggatata ggcatagctc tgtttgttgg aaatgtactt
    31261 gcgctgattt accatatcca cggcacagaa aataatgtga ttgtggacgt ggcccttatc
    31321 aatatgggta gtcagcacat agggatattt cccttgcagc acttcctcgg caagctgctt
    31381 cccgatctca tgggcctgtt ccggcgtggc ttcgccgggg gcaaaggatt gtatcaggtg
    31441 gtggcccaga ttattgccct tttggtatgc ctgcgccagc agcatttcaa attcaatgtc
    31501 cgctgtttca taagagcagg caaaggaggc caccagcagc ttgccgtcag ttttgtccgg
    31561 gttctcgatg tagtcaaggg cttttttcag cgttgacttg ataggatgta tctttgtaac
    31621 tgccatatct gcgccagcgc cccctttata tcctcgatgt cctgtgcgta caccggcccc
    31681 ataccgttca gcctctttgc aatctgattg acgttgacgc cgatcttctg tatctcggcg
    31741 gtctgcgccc ggatgtcgct ggtgtccatg ttgacgatat agccgtcaat gagcatcttc
    31801 cgggcgtagg ctgaaaagtt cttcgtatgc agcagcgcca ttttctgttc aatcatagcc
    31861 cgttcctccg gcgtcacagg gacgcgcagc acgatttttc gctttctgtt tgccatgctt
    31921 caccgtcctt tccattcagg ggtttgggga tttccccaac aagcaaaacg gacgcggccc
    31981 ggcagggacg gggcaggccg tttttccggg agtggctaca ctccctatgc ttgctacgtt
    32041 actgtttctc cactaacaag acgtttccaa agccccaaac tacccgcaaa atagccctct
    32101 ggaaagaaaa aagtgcaaaa aaatagaagc tacgctgtgc agctcccgct aaaagtaaaa
    32161 cagaggatgc cagttacaca tcctccgttt cattcttctt cggcttttca attagtatgg
    32221 cgctgtcaat cgcgccctcg atgatcggca ggtattcttc ggggcagagt ttcagcttgt
    32281 ggctgaccct ttgccgcagt tcgctttcct cccgcatgat ctccgggtta aagtagcgtt
    32341 ccacaggaag cccgcaggct ttaataagct gtatgacaac cggcagactg ggaatggccc
    32401 gtcgttttcg atgttggcaa gatagcgcca gtcaatattt attttctctg ccattgcttt
    32461 gcgcgaaacg cgctttgctt gccgggccgc tttcacatcc gcgccgaaag tttcaaagcc
    32521 gggacaatct tcaatattcg ccatatcgca cctcccactt acattgtata tttcatactc
    32581 tgcccgtgga atgttggtat atgcaccttt cttaaagttt atatttcaca ttttgtttct
    32641 tttattcttc gagcaaaaga attataatgt accctgtgga ggtgtactat ggactacatg
    32701 acgttgaaag aggcaggcga gaaatggggt gtgcccccac gatggataaa ctactattgt
    32761 gctgcgggac gcatccccgg cgctgtaaag atggcgacga tctggctcat tcccaaaact
    32821 gcggaaaagc cgattgacag gcgtacaaag aaaggaaagg cggttactga atagtataat
    32881 gaaaccggcg cattttggat atggttttga agagagagaa agcatggtat tttgtcacgg
    32941 aaaaactata agatgataga tggcaggctg ctccagaccg ataaaaagta ttctcatctg
    33001 aaacagaaag aaaagattta cacatggatg tatgaagaag cgaaacttta tcatgacaga
    33061 aatggaaaat gcccgaaaca aagacgagga agctgctgct gtatcagccg tatatggtag
    33121 aattgaaaag gccggcatct ggattcttta tggtgaagtc tccagacatt ggataactgc
    33181 tggtctaatg cgcctttgag tatggggtga ttgattttaa taccggggag gtacggcttt
    33241 ttgaggaaaa tattctggga tttacatttg gcgattatta catttcctgt aactgcaagg
    33301 acacggatga tgaagatatg aggaatatag acttgctgat tttctactgt cttgaacggt
    33361 attaggactg aatctgctgc gcggagtgcg gcaagagcga ccggagggag tacacacagg
    33421 ccctgcctgt gtgaaaagcc ataccgcaag gtgcattcgc aaaaaagagg ccgcgcattt
    33481 tgctgaggct tggggtgtcc ccaacaagca aaacgagaac gccgcaggcg ggcaagtggt
    33541 ggatcagaat atccgtaaag gatattctga tccattgctt gccagtatta tcgggatgtt
    33601 ttgacaaccg ctgtaatcga aacatcccaa acattaagaa ggtgttaatt attattatct
    33661 tgatttaatt cgtttaaacc aataatatag atacatacac catgaaaaga agcgagtatc
    33721 ccaatgacgg atgattaaaa tccgaaaaga aatcgctttg aaactacagg gaaactacag
    33781 actgttatgt tatcttctta aaatggaggg atttttatgt cgatacgaat tctacttgtc
    33841 gaggatgatg atcatatctg taatacagta agggcgtttc tggctgaggc aggatatcag
    33901 gtggatgcct gcacagatgg aaatgaggca tacaccaagt tttacgaaaa cacttatcaa
    33961 ctggttattc ttgatattat gctgcccggt atgaacgggc atgaactttt gcgtgaattt
    34021 cgtgcgaaaa atgatactcc cattctgatg atgacagccc tgtcggatga cgaaaaccaa
    34081 atccgggcgt ttgatgcaga ggcagacgac tatgtaacaa agccattcaa gatgcagatt
    34141 ttactaaagc gggtggaagc cctgctgcgg cgcagcggtg cgctggcaaa ggaaatccgt
    34201 gtcggcaggc tgacacttct gccggaggat ttcacggtac tttgtgacgg tacagagctg
    34261 cccctgacac gaaaagaatt tgaaatcctt ttgctgctgg tgcagaacaa aggcagaacc
    34321 ttaacgcatg aaatcatttt gtcacgtata tggggatatg actttgaggg tgatggcagc
    34381 acagtccaca ctcatatcaa aaatttgcgg gccaagctgc cggaaaatat catcaaaacc
    34441 attcgcggtg taggataccg attggaggaa tcataataat ggaaagaaaa gggattttca
    34501 ttaaggtttt ttcctatacg atcattgtcc tgctactgct tgtcggtgta acagcaacac
    34561 tgtttgcaca gcaatttgtg tcttatttca gagtgatgga attacagcaa acagtaaaat
    34621 cctatcagcc attggtggaa ctgattcaga atagcgatag gcttgatatt caagaggtgg
    34681 cagggctgtt tcactacaat aaccaatcct ttgagtttta tattgaagat aaagagggaa
    34741 gcgtactcta tgccacacca aatgccaata catcaaatag ttttagaccc aactttcttt
    34801 atgtggtaca tagagatgat aatatttcga ttgttgctca aagcaaggca ggtgtgggat
    34861 tgctttatca agggctgaca attcggggaa ttgttatgat tgcgataatg gttgtattca
    34921 gccttttatg cgcgtatatc tttgcgcggc aaatgacaac gccgatcaaa gccttagcgg
    34981 acagtgcgaa taaaatggca aacctgaaag atgtaccgcc gccgctggag cgaaaggatg
    35041 agcttggcgc actggctcat gatatgcatt ccatgtatgt caggctgaaa gaaaccatcg
    35101 caaggctgga ggatgaaatc gcaagggaac atgagttgga ggaaacacag cgatatttct
    35161 ttgcggcagc ttctcatgag ctaaaaacgc ccatcgcggc tacaagcgtt ctgttggagg
    35221 gaatgcttga aaatatcggt gactacaaag atcattctaa gtatctgcgc gaatgcatca
    35281 aaatgatgga taggcagggc aaaatcattt ccgaaatact ggagcttgtc agcctgaatg
    35341 atgggagaat cgtacccata gctgaaccgt tggacatagg gcgcacggtt gccgagttgc
    35401 tgcccgattt tcaaaccttg gcagaggcaa acaaccagcg gttcgtcaca gatattccag
    35461 ccgggcaaat tgtcctgtcc gatccgaggc tgctccaaaa ggcactatcc aatgtcatat
    35521 tgaatgcagt tcagaacacg ccgcagggag gcgaggtacg gatatggagt gagcctggtg
    35581 ctgaaaaatg ccgccttttt gttttgaaca tgggcgttca cattgatgat actgcgcttc
    35641 caaggctgtt caccccattc tatcgcattg atcaggcgcg aagcagaaaa agtgggcgaa
    35701 gcagaaaaag tgggcgaagc ggtttaggac ttgccatcgt acaaaaaacg ctggatgcca
    35761 tgagcctcca gtatgcgctg gaaaacacct cggatggcgt tttgttctgg ctggatttac
    35821 cgctcacatc aacattgtaa atatttaaaa cttaaatgat ttt
//
LOCUS       DADVXE010000021        35707 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.021, whole genome shotgun sequence.
ACCESSION   DADVXE010000021 DADVXE010000000
VERSION     DADVXE010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.021"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            209..1975
                     /locus_tag="KB913_001173"
     CDS             209..1975
                     /locus_tag="KB913_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBB6819547.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            2077..3336
                     /locus_tag="KB913_001174"
     CDS             2077..3336
                     /locus_tag="KB913_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6819548.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            3483..4784
                     /locus_tag="KB913_001175"
     CDS             3483..4784
                     /locus_tag="KB913_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6819549.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            4787..5638
                     /locus_tag="KB913_001176"
     CDS             4787..5638
                     /locus_tag="KB913_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6819550.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            5651..6466
                     /locus_tag="KB913_001177"
     CDS             5651..6466
                     /locus_tag="KB913_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBB6819551.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            6617..7783
                     /locus_tag="KB913_001178"
     CDS             6617..7783
                     /locus_tag="KB913_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6819552.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            8013..8660
                     /locus_tag="KB913_001179"
     CDS             8013..8660
                     /locus_tag="KB913_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBB6819553.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            8744..9688
                     /locus_tag="KB913_001180"
     CDS             8744..9688
                     /locus_tag="KB913_001180"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBB6819554.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            9823..11274
                     /locus_tag="KB913_001181"
     CDS             9823..11274
                     /locus_tag="KB913_001181"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBB6819555.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            11295..12131
                     /locus_tag="KB913_001182"
     CDS             11295..12131
                     /locus_tag="KB913_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBB6819556.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            12131..12790
                     /locus_tag="KB913_001183"
     CDS             12131..12790
                     /locus_tag="KB913_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6819557.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            12916..13605
                     /locus_tag="KB913_001184"
     CDS             12916..13605
                     /locus_tag="KB913_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819558.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            13611..14567
                     /locus_tag="KB913_001185"
     CDS             13611..14567
                     /locus_tag="KB913_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBB6819559.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            14611..15123
                     /locus_tag="KB913_001186"
     CDS             14611..15123
                     /locus_tag="KB913_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6819560.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(15379..15927)
                     /locus_tag="KB913_001187"
     CDS             complement(15379..15927)
                     /locus_tag="KB913_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6819561.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(16016..17197)
                     /locus_tag="KB913_001188"
     CDS             complement(16016..17197)
                     /locus_tag="KB913_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBB6819562.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(17433..18941)
                     /locus_tag="KB913_001189"
     CDS             complement(17433..18941)
                     /locus_tag="KB913_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBB6819563.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            19100..19291
                     /locus_tag="KB913_001190"
     CDS             19100..19291
                     /locus_tag="KB913_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819564.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            19494..20411
                     /locus_tag="KB913_001191"
     CDS             19494..20411
                     /locus_tag="KB913_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBB6819565.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            20404..21477
                     /locus_tag="KB913_001192"
     CDS             20404..21477
                     /locus_tag="KB913_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819566.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            21625..22143
                     /locus_tag="KB913_001193"
     CDS             21625..22143
                     /locus_tag="KB913_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819567.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            22124..22516
                     /locus_tag="KB913_001194"
     CDS             22124..22516
                     /locus_tag="KB913_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBB6819568.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            22592..23527
                     /locus_tag="KB913_001195"
     CDS             22592..23527
                     /locus_tag="KB913_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBB6819569.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            23660..24439
                     /locus_tag="KB913_001196"
     CDS             23660..24439
                     /locus_tag="KB913_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBB6819570.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            24432..24749
                     /locus_tag="KB913_001197"
     CDS             24432..24749
                     /locus_tag="KB913_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBB6819571.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            24993..26603
                     /locus_tag="KB913_001198"
     CDS             24993..26603
                     /locus_tag="KB913_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6819572.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            26760..27608
                     /locus_tag="KB913_001199"
     CDS             26760..27608
                     /locus_tag="KB913_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6819573.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            27839..28318
                     /locus_tag="KB913_001200"
     CDS             27839..28318
                     /locus_tag="KB913_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819574.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            28351..30579
                     /locus_tag="KB913_001201"
     CDS             28351..30579
                     /locus_tag="KB913_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6819575.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            30708..32351
                     /locus_tag="KB913_001202"
     CDS             30708..32351
                     /locus_tag="KB913_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBB6819576.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(32424..32969)
                     /locus_tag="KB913_001203"
     CDS             complement(32424..32969)
                     /locus_tag="KB913_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBB6819577.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(32992..33477)
                     /locus_tag="KB913_001204"
     CDS             complement(32992..33477)
                     /locus_tag="KB913_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6819578.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(33467..34279)
                     /locus_tag="KB913_001205"
     CDS             complement(33467..34279)
                     /locus_tag="KB913_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBB6819579.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(34418..35530)
                     /locus_tag="KB913_001206"
                     /pseudo
     CDS             complement(34418..35530)
                     /locus_tag="KB913_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
     gene            complement(35551..>35707)
                     /locus_tag="KB913_001207"
     CDS             complement(35551..>35707)
                     /locus_tag="KB913_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBB6819580.1"
                     /translation="SSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGT
                     LRYSLGY"
BASE COUNT        11680 a         6430 c         7134 g        10463 t
ORIGIN      
        1 ttgatcgctt aagataaatt caggacacta aatagtacag gaagtagact aaaactttta
       61 aaagttttaa gtctatctat ttggcaagtt taaaaaataa aaattcggta tcaaaaaact
      121 gttaccgata acatttttga aagcgttgtc ttttgcttct ctatcactta tagtgatgac
      181 gtcatattaa aacacaagga ggaaatcaat ggatacagct gcaatttatc atcgaccgga
      241 aagtgaatat gcatttctat atacgaatac aagatttcgt attcggcttc gtactaggaa
      301 aaatgatatc aaaaaagtat atgtgctatg tggagatcca tataccataa caactgaaaa
      361 atggtatcaa aaacaacgac caatgaaaaa atgtctaagt accaatgttc atgattattg
      421 ggaaattgaa gtgacgagcg aaacaagtcg cttacagtat gcgttccatg ttgttgggga
      481 agataacacg gactgttttt acggtgatca aggaattttt ccttatcgag aaaatgtgat
      541 tactgaacca aatttttatt ttcgaatacc ttattttcat caaatcgatc gattcactat
      601 tccagaatgg gtaaaagaaa cagtatggta tcaaattttt cccgaaagat ttgcaaacgg
      661 ggacaaagca aatgaccccg aacacacttt accttgggga agtaaagatc cagaccgaga
      721 agactttttc gggggagatt tgcaaggtgt gatggatcat ttggattact tgacggacct
      781 tggcatcaat ggcatctatt tttgtcccat atttaaagcc acatccaatc ataaatacga
      841 tacgattgat tattatgagg tggatcccgc ttttggcgat aaaaaacttt taaaaaactt
      901 gattgatgaa gcacataaaa gagggatacg tatcatgttc gatgctgtat tcaatcatat
      961 gggtgtccat tcaccacagt ggcaagacgt tctcaaaaac ggagaaaaat cgatctataa
     1021 agactggttc cacatccgtt ttttcccagt agattcttat cagatgactg acttaccaga
     1081 aactgctgaa aatatcccat atgatacttt tgcttttact ccattcatgc cgaaactaaa
     1141 tacagcaaat ccagaagtgc aaaaatattt gctggatatc gcaacttatt ggataaaaga
     1201 attcgatatt gatggatggc gtcttgatgt tgctaatgaa gtcgatcatc atttttggaa
     1261 aaaattcaga gaagcagtta cagaaatcaa accagacatc tatatccttg gagagatttg
     1321 gcattcctct caagcttggc tgcaagggga tgaattccat gcagtgatga attatgcatt
     1381 tacagattcg attaaagatt attttgcaaa aaagaaaatc acagcttcac aaatggtcag
     1441 tggaatgaat catcagcaaa tgctttacag agatcaggtg aacgaaggaa cattcaactt
     1501 attagattct catgatactg ccaggatctt gaccctttgc caaggtaaca aagaattgat
     1561 gaagtctgtg atggccttta tgtttcttca aaaagggtct ccttgtatct attacgggac
     1621 agaaataggg atgactggtg aagatgaccc ggattgccgc aaatgtatga tatgggagaa
     1681 ggaggaacaa gatctagagc tattcggttt tataaaagaa cttgtttctc taaggaaaca
     1741 gttgtctaag attatttctg aaggttctac tcagtggcta atagtaaatg atcgtgaaga
     1801 taagctctat ttcacacgga aactagaggg acagatcatc tatgtttact ttaatcagtc
     1861 aaaagaacct tgggtagtag aacaggaaaa tgaggtgatt cttagtcaaa attgtcagtt
     1921 gttagaagac gggaaagcag agatacgaca atacggattt ttgatcatgt gttgaaaact
     1981 gttaccggta acaacaagaa agcgtttgca aatgaagatt tgtgcccatt ataataaggg
     2041 tgtaacagca cgttgaatac aaaggaggaa atgaagatga aaaaaagaag tgtgaaacag
     2101 ttgggtttag ggttaatctc tttaggaatc ttaggcggat tagcggcttg tggcaatggt
     2161 aactcttcag cagaagggga agccgatgaa ggaaaaacgt taacagtttc cgttgattct
     2221 ggatataaag attatataaa cgaaataaaa aacactttcg aaaaagaaaa cgatgtgaaa
     2281 atcaagctag tagaaaagga catgttcgat cagttggaat cattagcgtt agatgggcct
     2341 gctggaaagg gacctgacgt tatgatggca gcatatgacc ggatcggtgc gttaggacag
     2401 caaggacatc tggcggaagt aaaactggga aatgaagcag cttacgatga aacagacaaa
     2461 gcccaagtga cttatgatgg aaaaatctac ggagaacctg cagtaatcga gacccttgtt
     2521 ttgtactata acaaagattt agtcgataca gcaccatcaa cgtttaaaga tttggagaat
     2581 ctatccaaag acagtcgttt tgcttttgag tcagaagcag gaaaaaatac aggattttta
     2641 gctaaatgga ctgactttta ttattcctat ggtttaattg caggttacgg tggctatgta
     2701 tttggtgatg atggcacaaa tccttcagat atcggtttga ataatgcagg tgctgtagaa
     2761 ggaatctctt atgcaacaga ttggttcaaa aatgtttggc caaagggaat gcaagacata
     2821 aaaagtgcag gagacttcgc cagccagcaa ttcatgtcca ataaaactgc agcaatcatt
     2881 gacggtccat ggcaagcgca aacatacaaa gaaaacaata tcaattatgg tgtagccaaa
     2941 attcctactc taaataatgg acagccttat caaccgtttg gcggaggaaa aggatgggta
     3001 gtcagcaatt atgctaaaaa caaagacctc tctcaaaaat ggcttgatta tgtaacgaat
     3061 caggaaaatc aagaaaaatt ctttgaaatg gtaaatgaaa tccctgcaaa ccaacaagct
     3121 agggaaacag caaaggctaa aaacgatgaa ttaacaacag ctgtgattga acaatatgaa
     3181 acagctcaag cgatgccaaa catcccagaa atgggcgaag tttggacagg tgcagaaaac
     3241 ttgatgttcg atgcagcatc aggttcaaaa acaccaaaag aatccgcaga tgaagcagta
     3301 aaaacaatca gtgaagccat agaacaaaaa tactgattaa aatgataacc gtccattttt
     3361 ataaaaaatg gaacaggtgc ttcagataaa agtggcaaga gcgagatgga aaattatctt
     3421 gctcttgttg ccattatctt aaaagcagtt tgcggtttag caagtttaga gggggcattc
     3481 agatgcagca agataaaaca agcaatatca acgaaaaaaa aatcacgctt tgttcactta
     3541 ttccagggat ggggcagttt gtaaatggcc aagcttttaa aggtatcgtt tttttcgcca
     3601 tattcgtcct attcattggt cagatgcttc tgggcggatt tcatgcattg gtaggattgg
     3661 ttactttggg aagtatacca atggaagatc attcattatt tattttgatt gaaggcactt
     3721 tgcaattcat cattacaatc attttcttga ttttttacgg tttgaatctt ttagacgctt
     3781 atcgagtagc gaagatgcgt caagagggca aaaaaatcaa tcggacgatg aaggaagtca
     3841 tacataatat aggtgatgaa ggttttcctt atctattgac acttcccgct tatcttctca
     3901 tgatttttac gatcattttc ccagtcctag ttacattgtt cactgcattt actaattatg
     3961 acttcaatca tattccacca gccagtttaa ttgattgggt aggggctaaa aactttttta
     4021 gtatcttctt tttaagctca tatcgtaata ctttttttgc agtcttttcg tggaccgtga
     4081 tttggacttt atgtgcaaca actttgcaaa tcacccttgg tattctcaca gcggttgttg
     4141 ctcaccagaa atttattaaa ttcaaacgta ttttcggtat cattttctta ttaccatggg
     4201 cggtcccagc ttttattact atcatgagtt tttcgaatat attcaacgat agcgtaggtg
     4261 ccatcaatac tcaagtgatt cctttcataa accagcttcc ttttgtagat atcagtgcaa
     4321 tctcttggaa aacggacccg aactggacga aagtagcaat tatcttagtg cagggctggt
     4381 taggatttcc ctatatctat gtgatggtta caggaatctt acaatcgatt tcagaagact
     4441 tatatgaagc agcaaaaatc gacggagcaa atgcatggca gcgcttttca aacatcacgc
     4501 ttcctgctgt cttcctagtg gcagcgccaa catttattac acagtatacg gggaatttca
     4561 ataatttctc catgatctat ctgtttaaca atggcggtcc cggaagcgta ggcggaggag
     4621 ctggttctac tgatattctt atttcctgga tctataaact tacgactgga acttctccgc
     4681 agtattctat ggcttcagca atcacgttga ttatctccgt catcgttatc tgtgtgtcat
     4741 tgctggtatt taaaaagaca aatgcgttca atatggggga ttaacaatga aaaaatttca
     4801 ttcgagtgct cgattccaaa aacgactttc tcactttttt acttactttt ttcttttaat
     4861 actgtcagtc attatcatct atccgctttt gatcacagca agtactgcct tcaagtcagg
     4921 aaatattgca gcttttagtt tagatctttc aagtgactgg actttaggaa actttactcg
     4981 gctattcagt gaaacacttt acgggacttg gtataaaaat acattgatca tttctgtcct
     5041 aacaatgatc gtacaagtga ctgtagtaac tttggcgggc tatacttata gtcgctatcg
     5101 ttttatcggc cgcaaatcaa gtctgatgtt ctttttagtg attcagatgg taccgactat
     5161 ggcagcattg actgcctttt atgtcatggc tttcttatta gaagcgctcg ataagtactg
     5221 gttcttgaca atgatctata taggcggtgg aattccaatg aatacttggc tgatgaaagg
     5281 atactttgac actgtaccaa tagatttaga tgaatctgct aaacttgatg gggcagggca
     5341 tttcaggatt tttttccaga ttgtattacc gcttgtcaaa ccgatgctcg ccgttcaagc
     5401 attatgggct tttatgggac cttttgggga tttcatgtta gctaagttcc tgcttcgaac
     5461 acctgaaaat cagactgttg ctgtcggctt acaaacattt atttctgatg tgacaaacca
     5521 aagagtctct ctttttgctg ctggggcaat tttgattgca ctaccgattt gtctattatt
     5581 cttcttttta caaaagaact ttgttaccgg cctgacatct ggcggaacaa aaggatagga
     5641 gcagagtatc atgcaaacat ttccgttaaa ctatttttcc gcattacgta cgccaactca
     5701 agtgtttgcg ggacgcaaac tattatcatg gcctaaattt ttcttgatat ttgtattttt
     5761 agtttccttg atggtcatgc ctgtgactct tttttatgcc aatcagatcc aagcgattcc
     5821 attagaacaa tttctatccg ttcattcgct gatcgatgaa caaggaaccc aaaaattttc
     5881 tgaacttgaa ttatctgaaa ctgggttaca agcatcgcaa caaacgatag ctgtgacccc
     5941 tgaaattttg gtaggtgtgt ctttatctga gaaacaacaa tccgatcatg gaacttttat
     6001 tgattttgag aaggaacaat gggtgatcca acaaaaggat aaatctggta tacgccgcta
     6061 tacgatgaat tatagcccat ctttccaacc agattctgta cgtacgcccg aagatttcca
     6121 acgattttta gaaagagaat tttatgccag taatcgtcca acaatcattt tatcttatag
     6181 tttaagtctt ggtcttgtcc tatttgtcat gacgagtctc attttattcg gggcttcctt
     6241 tttcttgtgg atgacaagaa aaagccaact ttcatccatt catacattca aagagagtgc
     6301 aaatttgatg ctgaatgtta tgggaatagg ttccatggca gcagcagttg tagggtttat
     6361 ccactttgac tttatcttga tgctaagtgt ccaaacaacg ataactgtct tgctgctttt
     6421 atgggttttt gtcaaaacaa gattcaaaga taagcgtgtc gaatgacaag tttaagcgat
     6481 ttatgcgaca atgaatgtga aaaaaatgaa aaataaagta gtttttgaaa aatttctgaa
     6541 aaaattaaac ttcttagttg attcttttct tttttagtat taacgtaata gggtagtttt
     6601 tttaaggagg aaaatcatgt tagagaaaac tttatacaat caattatttt cacgttcttt
     6661 ctcgctccct gtcgaagtaa attattggga cggtacaacg aaacaatacg gagatacgga
     6721 cactcctccc caaatcaaaa tcaatatcca tgaagaaatc ccaatgaaag agattacaag
     6781 taacgcatct ttggcactag gagaagccta tatggatcat cgaatcgaga tcgagggaag
     6841 tatccaagca ttgatcaacg atgcttatca gcaagcaaac agctttttac gaggaaaaga
     6901 ttatctaaaa tggctgccaa agaaagaaaa acatacgaaa caaaaaaaca aagaagatat
     6961 ccatgcgcat tatgacttag gtaacgactt ttataaactt tggctagatc caactttgac
     7021 ttattcttgt gcttatttca atacacctga agatacgttg gaacaagcac aaatcaataa
     7081 agtccatcat atcttagaca aactctttat caaagaaggc gaaacgttgc ttgatatcgg
     7141 ttgtggctgg ggaacattga tgttcactgc taccaaagag tataatgtca aggcaactgg
     7201 gatcacacta agtgaagaac aatacgattt gattaccaaa agaataaaag aagaacattt
     7261 agaagataaa tgccgtgtat tattaatgga ttaccgcgaa ctaaaaggcg aaacgtttga
     7321 tcatatcaca agtgtaggta tgttcgaaca tgtaggttct gaaaatcttg aaggttattt
     7381 caaagtggta aaagatttat tgaaaccaaa aggaacagct ttgatccatg gaatcagccg
     7441 acaacaaggc ggtgcgacaa atgcttggat caataaatat attttccctg gcggttatgt
     7501 ccctggtgtt actgaattag ttgataatat tacaaaaaac gatttgcaac tgattgattt
     7561 ggaaagctta cgtcgtgact accaattgac attagaacat tggacaaaga attttcatca
     7621 agtccaagat caagtcacga aagaaatggg tgattccttc tatcgaatgt gggatctata
     7681 tttacaagct tgtgcagctt catttgaatc aagtaatatc gatgtgattc aatatttgct
     7741 tgttcaacct ggaaacaatg acatcccaat gcatcgtgca taattgaggc aaaagtactg
     7801 tttaaagact atttaaaaag aagctaagtt ttatgatgct ccagaagtga acttttttgt
     7861 ctaacttcta ggattgtctc taaagcttag tttctttttc tttatatttt cataataaaa
     7921 gtttggttct ttaattttta aacatgacag aaaatttttt cttcgttata cttgtaatag
     7981 aatactattt tataacaaag gggatcgaat caatgaaaaa aactgttatt tatactagtt
     8041 tatttgcagc tttgttttta gctgcttgtc aatcaaatac caatcaaggc acatctggga
     8101 atacgtcttc cagtagcgaa cagcgctctt cacaggtatc ggactcctca acaaaagcaa
     8161 gcacatcttc gtctagccag acaaaaagtt ctagtgaagc aagtactcag tcagatatca
     8221 aagtgtctgc agctcgtgcg atcgaattgt tccaagataa atacccagat actgcaatta
     8281 ctagtttgga attagatagt gattggggat cttacttcta caagatagaa ggtgtcgatg
     8341 atcaaaaaga atacgaagca agaattgatg ctcaaaatga aaaaatggag acagagaatc
     8401 cagaaactct agatcgagat gaacaaaatg gtcaaaagaa aaaagaagat ggtctggatg
     8461 ttgataaatt gatcacgatt gaggaagcag caaaaatcgc cgtcgacaaa gtaggaagcg
     8521 gtacggcaac agattgggat ttggataaag atttaggtac tacttattgg gaagtcaaag
     8581 taaaagacgg caatcaaagt acatcagtca agatcaatag ccaaacaggc gaagtactgt
     8641 caactgaaca agatgattaa gaatttcttc ggaaaacaag agttgatttt tcttttagtc
     8701 atgatacact agacaaaata acttgtttga aggagcgatt tacttgagtt tagaaacgac
     8761 ctttgccaat catatctttg ccaatccttt gatgaatgca tctggtgtcc actgcatgac
     8821 tacccaggaa ttagatgaac tggctcattc agaagcagga gcatttatca ctaagagctg
     8881 tacgatcaat gaacgaaaag gaaatcccga accacgctat tttgatgttc ctttagggag
     8941 tatcaattct atgggacttc caaacttagg tttttcttat tatctagagt atgctcttgc
     9001 gtatgaaaaa gtgcaggaaa accaaaatca accgttattt ttttccattg ccgggatgag
     9061 tgtccaggaa aacttggaaa tgcttgagaa aatagaaaaa agtgggttta atgggatcac
     9121 tgaattaaat ttatcttgtc ccaatgtgcc tggaaaacca caactagctt acgattttga
     9181 ggccacttat gaaacactga aagaagtatt cagcatcttt tctaagccgc taggaatcaa
     9241 attgcctcct tattttgatt ttgctcattt tgatcagatg gctgatatct tgaatcagtt
     9301 tccattgacc tatgtcaatg ctatcaacag tgtgggcaat ggtttgtata tcgatacaga
     9361 acaagaagca gtagtcatca aaccaaaaga agggttcggc ggcattggcg gagagtatat
     9421 caagccgact gctttggcga atgttcgcgc tttttataca cgtttgaaac cagaaatcca
     9481 aatcattggt acaggtggga ttcggacagg acaagatgca tttgaacatc tgctatgtgg
     9541 cgcaagcatg ttacagattg gtaccgagct tcataaagaa gggccggaaa ttttttctag
     9601 aatcataaaa gaattaacgc agattatgtc agaaaaagga tatacgtcaa ttgacgaatt
     9661 taaaggcaaa ttacgcacca tttcatagca aagagacgaa ggtcatgatt gatcttcgtc
     9721 tttttttata aaaaacactc gtctgttcat tcctgtgcaa gcgtactcat tgtatgttag
     9781 acgaacttgt gggaaaataa cagaggcaaa aaggaggata atatgaatga tgcaacagaa
     9841 ttagcaaaag agcttaaaga aaaagaattt agttttcaag aactagttac ggatatacag
     9901 aaaaaaataa agaagcaaaa tcatgaattg aatgcgtttg tcgcgcttga accattcgag
     9961 agtaattccc acgagctatt gattccccag tcagaaaaag ggccattggc tggtatccca
    10021 tttcctttaa aaatgctcgg tcaagaaaaa aagggatggc tagctacttc aggatctcgt
    10081 ttatttgaaa cacaccgagc ttctcataca tctaattatg tgcggcaagc agaagcgata
    10141 ggtctagttc cttttggaca aaccaatgcg ccagagtttg gtttcaaaaa tattacagac
    10201 ccagtcatct atggcccagc aagaaaccct tggaaccttg aatgtacacc gggcggatca
    10261 agtggaggag ctgctgctgc agtttcatca ggaatcgttc ctttagctgg tgctagtgat
    10321 ggcggtggtt ctattagaat acccgcttcg ttttgcggat tgattgggct gaaaccttcg
    10381 cgagggacga tgccagttgg tccatatgct tggagaggat ggcaaggagc tgctattgat
    10441 ttcggcttga cagtttctat gagagacacg gaggctttat tttatgggat gagaagtatc
    10501 cattccggtg cgccatatca agtatcgcca gttgagtggc aaacacatcc aagaaaaaaa
    10561 cggttgaaga tagctttttg tgttgattca ccgatccact cacagattag tgaagaggca
    10621 gtacttgctg taaaaaaagc tgtagatttc cttggaaaag aagggcatga tttgacagag
    10681 attccttacc cactagatgg tcgtaaactg atcacgtctt attatcagat gaatggcgca
    10741 gaaacagcag caatgatccg ctcgattgaa acaggcatcc agcgagctgt cagaaaagaa
    10801 gaacttgaac ccatttcttg gactttgttc caatatggtc agaagctctc tgccgctact
    10861 tacatcgatt ctctgcatgt atgggatgaa gcagcaattg tcatggaaaa cctacatcaa
    10921 gaatacgatc tattcctttc accaacgact gcatttaccg cccctaaaat cagcgaagat
    10981 ttgcaaagtg atgcgataag agcacagatg gaacacatca gtgattgttc tgaagtagaa
    11041 ggtttagacg ttgtttcttc catgtttgag gagagcttga agatcacacc ttatacacag
    11101 ttggctaatc tgactggaca accagcaatc agcttgccta ctcatttgac aaaagaaaac
    11161 atgcctctag gaatccaatt tatggctgcc agaggaagag aagatttgct atttcaaatc
    11221 ggctatctat ttgaagcaaa tcatcagttc catttaccaa atccatggaa atagcagaaa
    11281 caaggagaag aagaatgaag aaaaaaagat tgtttgctct aataactagt gcctttttta
    11341 ttttaagcgc ttgcggtaca gctgccgcta atcaggaaga taacagctgg agtaatgtag
    11401 aaaaaaagaa agaattagta gtagcgactt ctggcacact gtttcccgca tcttattata
    11461 atgatcaaaa tgaattagtt ggttatgatg tagatttggc aaaagaggtg gctaaacggt
    11521 taaatgtcaa aatctccttt aaagaataca acgtggatgg acaaatcact tctgtttcaa
    11581 aaagagaatc agattttgct gcgaacgatt ttggtatcac aaaagaaaga gaaaaaaaat
    11641 tctccctttc agagactttc aaatattcat ttgacagtat gatcgtacga aaaaaagatg
    11701 attcaggaat ccactcactt gaagatctta aagggaaaaa agcagctggc gaacccaata
    11761 ctagctatat gcgtttagcg gaaaaacacg gagctaaatt agtcacatat gacaatgcca
    11821 cgaatgatca gtatttaagc gatgtagcaa atggtcgaac agatgttatt ctaaatgatt
    11881 attatctgca gaaaatggcc gtatctgctt taccagatat ccctgtaaaa atactggaga
    11941 acgtttattt caatgaaaac gaaagtggtt ttttattgaa agaaggaaat gatgctctga
    12001 aaaagaaaat cgatggcgta ttaaaagaga tgaaagaaga tgggacgaca aagaaaatat
    12061 ctgaaaaata ttttcaaact gatgtttcag tcaaaccgaa agaaacgatg gctgagtcgg
    12121 tgagtgagtg atgtactttc ctctaattga tttttccctc atgtggactt cacttccttt
    12181 cgtactgcaa ggcttggtat acacattagg gattggcttc gtgtcgtttc ttttaggaaa
    12241 tctggtaggg ttgcttttga cagttttagg tcttttggat tggctgcctc tgaatgtatt
    12301 tattcgtttt tatttatcgt tctttagagg cattcccgca ctagtcctgc tgtttctgtt
    12361 atattttggg ttaccttatc aattaagtgc cttaacggct tcagtcatct gctttacgat
    12421 taccagcagt gcatttattg gtgaaatcta tcgaggatca ctagcaggcg tttcttcagg
    12481 tcagtgggac gctggtttag cttctggttt ttctttcttt ggggtattga aatatatcgt
    12541 tttgccgcaa gcttttcgaa tctcagtacc ggcactcagt aacgtagcta tggatctagt
    12601 gaaaggtact tcgttagcag caacaatcac agtgccagaa atatttcaaa aagcaaagat
    12661 cataggcggt cggacattcg attatttttc tctctatatt ttagttgcac tgatttattg
    12721 ggtcatttgt atcgggatcg aaaaagtgca acagtattta gaaaaacgtt ctatgcatca
    12781 gtcaatctga aaaatagaaa tggtgctagc gtggctggca ccatttctat tttttgtttc
    12841 ttgtatattc tgcctagtat tttaaaacca tttcatgtaa aatgtaaatc gaaaatatgt
    12901 tcggaggtag aaaacatgaa gaccccgcta accatcgaaa tagaatcctc gttataccaa
    12961 tattgcatcg agcaaggcgg cttggttgta gaagaagtca cgatgcctga tgaccaagga
    13021 attgtagata cgcttagctg cttgacaaaa tttgatggaa gccgagaatg gcgatgctat
    13081 gagctgaaag tgacaaaagc agattttcgc tctacagcca aactgtcatt tgttggacat
    13141 tataattatt ttgttttacc aagtaaacta tatgaagaag taaaaactga aatccctaca
    13201 ggaataggtg ttttagtgta tcgtccgtac acggttgaag aggagatgcc tgcctctggt
    13261 acatttctga ttgcgaaaaa agcagcaaag aaagagcttg ctgtaccgga agaagctttg
    13321 acaaaccgct tcatggcttc tttattcagg gaagtaagaa aagcaaagca aatggagcga
    13381 ggcgtaaaat attttccaac agatcaattg tacaaagaat tgaaaagacg ttcagaaaat
    13441 caagatccat tttctaacga acgatattat gaacggtttt tagaggaaat agctagtcag
    13501 gcaatcaatg agttgcaaga agaagttatc gcgcttcagc atgattatga atatttgagg
    13561 caacaacagc agatccgtcg gttgcctaca gagccattgg agtgaaaaat atgtactatc
    13621 cttatttaag aggaaaacaa tttgacctat tagcattaaa agaagcactg tcgcgaggat
    13681 tgctctccaa taaaatccaa ccagtgatcg aaccagtacg tgattccgct acgcttaaaa
    13741 atgtgatcga attatttcaa aaaaagcacc atcgaatcgc tgtgatccaa aatccccaag
    13801 taggacaatt caaattattc gatcagcatg tgcacagttg gacagtcaaa gaaaatagct
    13861 ctgtcgtccc tgcacagatc ttaacgccag aaaatctcag tgaagtactg gattcacctc
    13921 cagcgtttct tgttttcgat ggacagcact acccaaaaga tacagaggtg tggaaacagt
    13981 tggcaggagt tgattcgaaa tttttgatac cagatactag tcgctttcgc atctggctgc
    14041 ccgaaaacaa aattgtgatc cgtgactctt ttcaaacgag aaagcatgtt gaaagttatg
    14101 cagataaaac agatgacttt tttagtgatg actatctttt tttccacgca gacggatata
    14161 ttggattttc tgatttcacg atcgaaggta gccgttattt cgataaaggg ttccctagcc
    14221 gagcgcttgc tatccatcta acgtatattg atgcttacgg caatatacgc gtgaaacatt
    14281 ttgtctctga cagtaacgac tctgctaaag accaagcatt gaagtttctt gaagcaggag
    14341 ataaaatgaa aaaatggatc atgcgtcacc atcatcaact cttgattact tcaggaatga
    14401 ttgaattatt ggctctttac cagcaacaaa aattccctgg actgggagtg ttgaaaaagt
    14461 ggtcacttat gcatcatttg gaacttatta gtcacctgct agatcatcca aaagattggc
    14521 ttaaatatta ttcaaaagtt caggaactat atgaagtgat ccaatgatta gataatgtaa
    14581 atgaaaaagg aatagaaaag aggaaactgg atgtatattc ggcaaacaag gaaagaagaa
    14641 gtagaagaag tggtagaaat cattaatgcc gcagcggatt tcattgcttc gcaaggctct
    14701 cctcaatggc aaaacgggca gaaaccaaca aaagaaacga ttttgaacga tattgaaaga
    14761 aaagaaagct atgtattaat agtggaagat caaattgctg gaacagctgc attagtctca
    14821 agcgtggatc ccgtttacac aaaaatagat ggtagttgga aagaatcaac tggtccttat
    14881 ttatcgattc atcgtgtcgc tttagcagaa agtactcgag gaaaaaaact agcaaaaccg
    14941 ttcttagaac atttgttgac gattgcagcc agcaaaaata tccaagatat ccgtatcgat
    15001 acttatccag ctaatgaacc gatggaaaag accatctatt ctgctggatt cacttatcaa
    15061 gggatgattg aatttccttt tgaacacggc gaaagaaaag catatcaaat aatcatcaat
    15121 tgactataaa atcatctgag caaagataaa gacattaaca ctactgaaaa aaacaatcat
    15181 atgatagcca agaggttgta acagaagtgg ccagcttcaa aaaacaagaa agaatttccg
    15241 aaaatgcttc tcaaattttt gtggaatttt agcgtatttt acgaaatagc tgctttctga
    15301 aactcccttc atcgagaggt cgtgacatag cttttgtcac gacctctcgg cttatcctac
    15361 gagtattatt cgatacattt atatcaataa tccttttttt attttatctg cagcttcttg
    15421 gaacgctcca tcgtttgaca cgactaaaag tgaggggata gctttcaaac gtttcaactg
    15481 tgctaaatct tctacataaa ccgccagtct ggctgaaatc tgttcagatg aatctccacg
    15541 ttttttcagg cgcgattgca atgtttcttt agagatcgta ataaagatag gacggactac
    15601 cgtcccgaaa tactcatata aatgccaaaa accatttgct gtcaaaacgg cgtaacaatt
    15661 tcctactgtc agtttctttt taatttctgc tttactggaa ccatatttat gttgagcata
    15721 ttggtcccac tctgcaaact catttccctt gatcatctga ttgaatgtat tgtcagaaac
    15781 aaaataataa tcctcttgat ctttttcccc aggtcttggt gatcgattcg tgtaagtaat
    15841 gatcttttgt tccggctgaa aaatagcttc tgcgagtgaa gtttttccag aaccagaagg
    15901 accgataaat acatagcaat aattcattgt catttctcct ttgatgattg aacaagtgaa
    15961 aaagctttgg aaaatatttc caaagctttt aaaagtaact ttgctttttt gtatattata
    16021 ccagcaagcc agtcacaata gcacttaaaa agctgactaa agtcgctgtt agcaaaattt
    16081 tcaatccgtg ttttgcgaca agatttcctt tttcttcatt taatcccttc atcgcaccag
    16141 aaatgatccc gatagaagag aagttggcaa atgaaacgag gaagacagat ataattgctg
    16201 ttgtacgctc agtaaaatgg aaattaccat ttgctaattc tgtcatagca acaaattcat
    16261 ttgtaaccag tttagtcgcc atgatactac cggcatccac tgcttctttc catgggattc
    16321 cgctgatgaa ggcaagaggg gcaaagatgt aacctaggat ctcttggaaa gtgatgccga
    16381 atatcccgtg gaagatagca ttgatcatgg caatcaaagc aacaaaaccg ataagcatag
    16441 cagcaaccgt gatcgccaca tggaaaccat caagaatgta ttctcccaac atttggaaaa
    16501 atgtctgttc tttgttttct tcaatgatca gctcatcttc tttttcttct aatacatagg
    16561 gatttacaat tgaagccaga atataaccgc caaataagtt caaaacaagg gcagtgatca
    16621 catatttaga atcgatcagt gccatataag atccgacgat cgacatagaa actgtagaca
    16681 tagccgatac actcatggtg aacaaacgtt tctcagatag gaagggtaat tcctttttta
    16741 tggaaataaa aacttccgat tgtcctaaaa tagcagaagc tactccatta taagattcca
    16801 atttgcccat cccgttgatt ttacttaatc ctagaccaac agctttcata aataatggaa
    16861 gaatcttgat atagcgtaga ataccgataa tagcagaaat aaatacaatt ggcatcaata
    16921 cggaaagaaa gaaaggtgca cttcctttat ttgctacacc ggcaaaaaca aagtcaacac
    16981 cttgcccagc aaaagcaaga agatgatcaa acatttttgc caatacagaa acaaccgctg
    17041 taccaaaagt tgtacgtaat aatacgaaac caagaacaag ctgtaaaacg aacatcacaa
    17101 ttagtggttt caatttgatt gcttttttgt tactgctgat caaaaaagca agccctaatg
    17161 tgacaaataa accaataata cctaataaat aactcaaata atcactccta ttccaaattc
    17221 cgttttattt tacctgtttt gcaaataaaa tactaatctt tagtgaaatt ttcattactt
    17281 ttttagagtg aaacgcattc attttccatt agaaaataaa gcgaacaaaa taaaaggttt
    17341 aaaaagtgta acgtcttagt aaagtctata aaaaaacgaa actatcgatt aagctaatag
    17401 tttcgttttc aacatttata agtaaacttt ttctattggt aatatagatt ttcggaaggg
    17461 tagacaggtg cgcaggtaat atcgattcct agttttttca atgtttgttc atcattttta
    17521 ttgaccatca cagtagagtg ggcttgtgct ccctcaagtt cagctagttt atcataagca
    17581 acttgagcga ttggattcgt tactgcactg attgataaag cgatcaagac ttcattgatg
    17641 cttagtgcat ccaaagagga atgaagtgtc tttgatttca atccttgtat tgtttcaaga
    17701 actaatggtg acaataaagg aatgtcatct gcgatatggg ctaaatgttt tactgcattt
    17761 aagataactg ccgctgacgc atccatcaat gaacttgtac gcccggtaat gatgacttca
    17821 tctggtaatt cgattgcaat cacagcagaa ggatcttttg taggactttg cgcttgaatc
    17881 ttatctgcat agtcatgggc agggactacc acgtttcggt cttcaggacg taaaccgact
    17941 tcttccataa tcagtttgat tcgattaact gcttcttcgt cgatcaatcc ttttttgaag
    18001 tcgcattctg tttggaaata acgacggatg atttcttgtt tagaggcttc ttggacaacg
    18061 gtatcatcca cgatcccaaa tcctacacga ttcacaccca tgtcagtagg agattgataa
    18121 acagattctt taccagtaat tttttcaata atacgtttga ttacaggaaa tgtctcaaca
    18181 tcccgattat agttcacagc tactttattg taggcatcaa agtggaagga atcgatcata
    18241 ttgacatctt ttagatcgac tgtggctgct tcataagcaa tgttcagcgg atgtttcaac
    18301 ggaacattcc atactgggaa agtttcgaac ttggagtaac cagctgcatg tcctttttgg
    18361 ctttcatgat acagttggtt caaggaagta gcgagctttc cacttcctgg gccaggagct
    18421 gtcactacaa cgattggttt agttgtttca atatactcat tttttccaaa accatcttct
    18481 gagacgattt tttctacgtt gactggatag tcttcgattt ctgagtgttt atagaccttg
    18541 atgtttcgtc tttctagttt attgataaag actttcgtgg caggctgtcc actatagcga
    18601 gtgataacga cactgttgat taataagcca taaccacgta attcatcgat taaccgcaag
    18661 atatccatat cataagtaat cccataatca ccacggatct tattacgttc aatatctcca
    18721 gcatagacgc aaatcagtat ttcagcttga tctttcaatt tttgcagcaa tttgattttc
    18781 gcatcttctt caaatcctgg aagtacacgt ttcgcatgct tgtcgtcaac tagcttccca
    18841 ccaaattcta aatataattt gtcatagtgg ttcactcgtt ccaaaatata cgctgactgc
    18901 tcttcaatat atttttctga atcaaaacca atttttttca ctaggttccc tccttaagta
    18961 ctaaagcatt ttttcatttt tttgaggatt cgtcaactgg aagagcgaaa ttcctcaaaa
    19021 aaacaaagaa aatggtttaa accaacttgt ctagatagtt attcattggt atgatagttt
    19081 ttgataagga aggtgctaca tgaaaaaaag acagaaaaag aaaaacgcat ataaacacta
    19141 tatccgttcg atttttaccg gttatgaaag aatgcttgaa gatcccgaat tggaacaatt
    19201 gacgtttact tatctaaacg aagaaacgca gctaactcgt gatgagcatc agcgcattca
    19261 tttcacaaca agagatctgc ctagtaaata aaaaataaga taaaggtcat cggattcgat
    19321 tctgtcctat cagatggaaa gactagttga tcgaaaaaaa ggctgtacca aattttggtg
    19381 cagcctgttt tatggagcat tgcccgctct tttttataac aattttttac agaaaatggt
    19441 actattgaag tattaataag tgaaaaacag atgagtaaga ggaggcaagt agtatgaaag
    19501 agccagatac aaatgcaaat tatgagccag acgaactaga ggagacgaat gcggatcagg
    19561 atacaggaca agaatcgtct tctttttacg atatcaaaga aaaagcaagc atgaatcttt
    19621 cccaattatt agaagactta caggcttttg aaaaagctgt ccgcgaagaa gatatccctg
    19681 agatctaccg tttatacaat ggccgattga atgaagaatt aaaaagaagc tcaaatgaaa
    19741 atcacgagat cgatcaattg ctgatgcgta agatccatga tcgtttttta caggaatttc
    19801 cttttatgga acaagtagaa aacatctcgc caacgatgag ctattacaaa atcggcactt
    19861 attaccatga tcggcccacg gtcggtattg atgcaagtct gccagaaatt tttgttttgc
    19921 ctaagatcga tgaagagtgg gagaaatatt cccaaccgga gtcaacggac tatgacaaaa
    19981 aaatcaatga gctagacgca aaggtgatca ctgctcagac agaaattgaa cgtttagatg
    20041 aacaaataaa agaaatcaat cgacaaatga ctgatttgaa cgacaataaa ggattcttga
    20101 atcgtaaaaa aatcgaggaa gaaattcaag aattagagaa gaagaagcaa gtactatcta
    20161 atgaaaaatt aggctggctt ccttatattg agacgcctga aacaatccag cagcaaaaag
    20221 aagcattgaa gcaagaagca agagcagacc agcttcgtgc agccatcgta gaaaaagaac
    20281 aaaggcaaat cagacgctat ttcggtagca aagagggatt cggtcaagca atccatgaat
    20341 tcttgatgaa ttatcttggc aatgagaatc ctaataatca atctaatgaa ggaggttccg
    20401 agtatgaatg aacacgatga agcagaatgg acaaaaaatg aagaacaaac agaagatcat
    20461 gaagaaacga acacttcatt ggaagaacaa acaagtaatc ctctggatga cacagaagaa
    20521 atccctatgc tagaggaaac aaaaatacac gaaaaagaaa aagtaactcc gacgaatacg
    20581 aatactgcag aaaacaccca tgcttacgaa ataactgaaa atcccgggta tttagaagga
    20641 aaagagcaag atcatcaaga tatcgtcagt ttgattgaaa cagcggaagc agaattagcg
    20701 gatttacgta tgagaaaaga tttgatcgaa tcagattttc cacaattatt agaatcatat
    20761 gatcgtttta tattgaatga agaaccaatc tccacgatcg gaaagacaag cctgatcgaa
    20821 tacttcacgt atgaattact gaaaccgttg aatgatattg gtctggaacg gtcaaattca
    20881 gcttatgaca catggaaaac aagacatttt tcgatcaatt atacgttgaa tggacaaaac
    20941 gaattagtct tttcctttgt attaccgacc atcgatcaac gataccaagt ggaatcgatg
    21001 agtctcctaa acgtatcacc agagacaatg gaaatcaatg tccaagatga ccgggtgctt
    21061 tctttgatcc gacactggtc agtggatcga gtattctctg cagggcagat cacgatattc
    21121 aatcacaaat tgaatcaatt attagcccat gcaagaacac ttggttttac cgttaatcag
    21181 acattactag acaatacgaa gccacttcgt ttgaatcttc agagcgaatt tgaattgacg
    21241 aatgaagtat tggatgatat ttttatcgtg gcaatgaaaa atccatccta cgatatggaa
    21301 aagatcaacg aaactactta tcaagtacga ttagataaag gacagtcttt aacgataaca
    21361 acaaacgaaa aagatcaaac agtcttgtcg atctcatctg gagactaccc acgatctgtc
    21421 attgatttct ttatcaatta cgaattcttg gtcccattaa tggtgagaaa gtcctgattg
    21481 gataagttgg attaccagat gtcattcaga taattctgtt ccaaaggact tgcggcagtt
    21541 atccagaata attgtcacaa gtcttttctg tatgtactaa atggacgtga ataacttgct
    21601 gatgaaggag ggatttcatt aggaatgtcc acaaataaaa tagcacagct tagcttattg
    21661 tctgctgctt gtgtagcagg taggatcgct tttcaattta ttccgaattt ccagccaatg
    21721 actgctattt ttttatttat agtactttac ttaagcttaa aagatgcgtt aattgtcatg
    21781 agtctttcta ttgcgatcag cagtttttat tttggtgttg gaccatgggt catcggccaa
    21841 tggatcagct atactgttgt tctgagtttg ttttcaatcg tctgcttgag aaaaacagtg
    21901 caaaggaatc tatggttaaa gggagtctgt ttttttctgg cgggcatggt ttacggaata
    21961 ggtatgaccg tttttgatac gctgttatat cgtttgcctc aaccttggat ctattacctt
    22021 caaggggtgt cgtttgattt gatgcacagt ataggcaatg ttgtgttctt tcttgttttt
    22081 ctgccagtcg tcaaacgttt ttacaatcat tcaggaggaa aaaatgaaaa aaataattta
    22141 tagtttgctt gcaatgagtg tcagtatact cattttgaca agttgcagta caacctatac
    22201 acaatcggct tccaaccaaa aggaggaagt aaaaacatcg caaaaagcaa caatcacgtt
    22261 acaagaaaat ggtcaaaact tttcggaaaa agaagtgttc ttcaaaaaag gcgatgattt
    22321 actgagtatt ttgaaacgaa attttgaagt caaagaagat aacggcttca tcacttcgct
    22381 tgaagggcac tcacaggatg agaaaaatca actctattgg atgtttactg tggacgggaa
    22441 aagtgctact actggtgcca aagagatcaa attgaatgat ggacaatcgg tcattttcaa
    22501 tttgtctaaa ctataagttt cataaaaaac tgttaaaggg cgaatattgc cataattcag
    22561 tgagttcagt tgatgaaaga aggaaaataa catggaaaat tttaaaaaaa gcggaatgtt
    22621 ttccgtaatt gctgctctag gggctaatat tctagttgct atcagcaaat ttgtcggcta
    22681 tgcaatcagt ggcagtgccg ccatgctaaa cgaaagcatc cacagtatcg ttgattgcag
    22741 caatcagatt ttgctgttat tcggtgataa acaagccaat aaaggacaga gcgagttgca
    22801 tcaatttggt gaaggacgag caaaatactt tttcagtaca atcgtcgcaa tgatgctttt
    22861 cttcggcggt ggggcacttg gggtgatgga agcttttgaa aagttgacgc atccatccca
    22921 tgaagtgggt aatccgatca ttgttatagc aatactgtta tttggtttgg taatcgaagg
    22981 aagttcgtta cgcgtggcaa tgaaagaaat caaagaattg aatactgaaa aactttccac
    23041 gatgcgcttt ttgcgcgaaa gtcgacacag tgaaatactg attattttta cggaagactt
    23101 gtgtgctgta atcggtttgg tcttggcttt agcaggaaca atattgactt atgcaaccgg
    23161 gattgctgca tttgatgcga tcagcggatt gctgatcggt ttcttgctga tgggagccgc
    23221 cattttccta gcaaaagaat tttatagtct gatcatcggt gaaagcgtga cagcaagcga
    23281 tttatcaaaa atcaagttag cttttgaacg tcctgagatc agtcggctga tcgatataaa
    23341 aacagttcat ttaagtccaa cggagatttt agttgcagca aaagcagata tcgttggtaa
    23401 caaagagaat gaagcttact cggtcatcaa tgatattgaa aaaaatatgc gtcagtctct
    23461 tcctgacaag aagatgtata tatacattga aacagataaa tatgacccaa attattctcg
    23521 taaataaaac gtttattcat gaattgaagc aaaaatgaga aaaatataat cttgttttta
    23581 aataaaacgg ctacaattta gcgaatttat gttacaatga gtccgctgtt tatttgttgt
    23641 aattaaagga gatattttaa tgaacaaaaa gaaaagtgcg ccatggcttc aagctttgca
    23701 tgcagtgatg ccactttgta taagctatat accagtagga ttagcttgcg gagtattgtt
    23761 gcaaaaagtt ggatttgatc ctctcttatc aggactgtta tcgattctgg tcttttccgg
    23821 tggcgcgcag tttttagttg catctatgct tacgacgcaa gcatcatttg caacgacatt
    23881 attgatggtt ttctttttag aattacgcta tacattatta ggagcaagtc ttgccggttt
    23941 tatgaaaaaa gaaaagcgga cgtttttggc tgtcttttct caatcactga atgatgaaaa
    24001 ctatgcggtg aactacttaa agttttcaac tgacccttcc tggaataaaa gaaaggcttt
    24061 atatgtcaat tggttctcaa tgactgcatg ggccggtagc aatatgatcg gtaatttttt
    24121 cggctcggtg attcgagtag atgctgacct tgtccatttt gctttgacgg ccatgttcat
    24181 tttcatgttt atcatgcaga tgaaaagcgc actactgatc tttacaggtt tattctcagg
    24241 cgtattaggg gtcgtattca tggtattatt ccaaaatact ttcggattga ttgcagcaac
    24301 agtcattgct tcatttgccg gatttatgct ggagaaggca ttcaaaaaag aaaaagctaa
    24361 gaaactaaga gaccgcggta aagatgtcaa tgagccgctc ttcaacttcc cggaacagga
    24421 ggccaatcac catgactaaa ctatatttgc tacttttagt tgcttgtctg ttcatcgtgg
    24481 catatatccc gcgcttgttc ccgatgcttt attttactca tcgaaaagtg ccatcctggt
    24541 tcagtgactg gatgaaatat gtaccggtgg cattatttgc ggcgttagct tttaaagatg
    24601 ttttcattac tcatgaacat ctggatattg cttggaatat caaaatagct gcaatgattc
    24661 tagtagcagg cgtggcttac aaaacacgtt cgatggcgtt gtcagttttg acaggacttg
    24721 cgtctgtctt tttgctgtct atgctttaaa ctgttttatt ttattaaaaa cagagattgc
    24781 gacataagtt gttcaaactg atctatccga actgcatttg caacagtcaa ttctggatgc
    24841 aagtttattc gtagggataa aaaagattag tgttggctta tgatgcaagc tcttttttat
    24901 tttaggaatt agagagggat ttgtccttct atgatttttt gctataatag ggaagatgtt
    24961 tattttatga aagaatagtt gagggaattt aaatgaataa aaaattgatg caaggaacat
    25021 tttggctaac ctttgctaat cttctatgta aagttttagg ggtagtctat ttgattccct
    25081 ggctaagtat gatggggaac aatcaagatg gtatgcttgc tacgacattg tataatgttg
    25141 gctatcttcc ttatggattg ttcctgatgc ttggtacagt cggatttcca aatgcgattg
    25201 caaaaaaagt agctgtagcc acaaaagaag gagataacgc tgcttgtcgg ctgattttta
    25261 gaagtacgat caatatcatg tttgtcatcg gtatcgcctc tgctgcactg atgtatttat
    25321 ttgctccttt actagccgga atcagtccga ttgctaacgt taataatggg atactagcta
    25381 tcagaagttt atgcccatct ttgattgcta tcccaattct tagtgcaatg agaggatatt
    25441 tccaaggaaa aaatgatctg cggccttatg gaacttcttt gattatcgaa caggctgtgc
    25501 gagtgatcgt tatcttggct ggtacttatt acttgcgcgt attgactgac ggaaccatat
    25561 tagaagctgt attgatcagt acagtcgctt ctttcttcgg tgggttagct gcgattatcc
    25621 atatgtatat cgtcggacgc agaaaagact tcttcgaact taaagatttt ttgatttcca
    25681 gccgttattt cgaaagagaa aaccgatctg cctctgtctc tatcattcgg gaaacactac
    25741 cgtttatttt tgtcggctca gtcattacta tcgttcaaat gatcgaccaa gtaacgatga
    25801 aaccactgct tcactttttc cgtccagaga tcgcagatca gcaactggaa ttcttattca
    25861 gccgtgcttc tgtcaatcca aataaattga cattgatcct gatctccatg gtaggaacag
    25921 tagctataag cagcttgcca atattaagca cgatgaagaa aaaagatcgg atacaaatcg
    25981 aaaaaacagt aggagatagt ttttcgattg cgttattgat tcttcttcct tcattgactg
    26041 gaatgtcttt attagctgga ccactataca cattgttttt tggctatgat cctgaaagtg
    26101 tcggatattt ccaaatggct ttgctagctt ctttgttttt ctctttattc acgatcctat
    26161 ctacgatgct tcaatctttg aatcaccatc gttttgcgat ccgattaact gtagaagcaa
    26221 ttatcctgaa agtcatcttc caagtaatcg gattaggatt agttggcgga tacgggatga
    26281 gcttatcaaa tggcttagca ttcggtattg tctttgttcg cggctatcac tttatgtgca
    26341 aagaataccg aatagcacct ttagcaaaga tcagcaattt tttcttaaaa actttccgct
    26401 ccaccctgat tatgcttgca gtatgttttg ccgttttctt tttgctgaat cagcgattgt
    26461 caatggaatc aaaaagctat gcaatgattt attgtgtggc tgtaggaagt attggcggct
    26521 tagtattttt attttctcaa ttcggaaaaa atgggtttcg aatgttgaaa aatgttaaac
    26581 atcatagcag aagcaaagaa taggttaact aatcgttttt tgctgtcact tgaaaaacgg
    26641 caactcgtat gattacgctt gtcgtttttc tattttccaa ttttagtttc atatctaatc
    26701 ttacttatga tatagttata aggtctggaa aaattctttg aaacgaggaa attaaacaca
    26761 tgaaacttgc agtagttaca gatagttcgg catatctgcc ggaacgtatc aagaaccatc
    26821 ccgacttatt cgttattcca atccctttga ttatggatgg gaaaatttat aacgaaggaa
    26881 tcgatatcga agcggatgaa tattatggac ttttaaaaaa cagtaaagat tttcctacta
    26941 cttcacaacc tgtcgtaggg gaagttttgg gtttatatga ggaattgaaa gagaaagggt
    27001 atgacacgat tttaagtatc catctttctt cagggatttc tggctttgtc aacacattat
    27061 ttgcgatgaa agatgacatc agcggagtaa cggtcattcc ttatgactct aagatcacta
    27121 gtatgccgat gggacacatg gtagaagctg ccttagactt aaatgatgaa ggtcagtccc
    27181 ttgatgaaat acttgcacat atcgatcgaa tccgagataa tacctacgct tatctgattg
    27241 tagatgattt gaacaattta gtacgaggag gacgtttgac aaatggtgca gcgctgattg
    27301 gcagcttatt aaaaatcaaa ccgatcctga cattttctga agggaaaatt gttttattcg
    27361 aaaaaatccg ttcaagtaaa aaagcatttg ctcgagctga agaaattatt ggtagaagaa
    27421 ataacgaaat acaaccgcca gtcaaacttt acgtgataca tgcaaataat ttagaagtag
    27481 cgattgcgga gaaagagaaa ttgcagaaaa aatatccaaa tgcagaaatc gaaattggtc
    27541 atttcggacc agtcattggt acacatttag gtgaaaaagc catcggcatt gccatttcag
    27601 cgcaataatt ccttttattc aaaaaacata ccaaaaatat tccaacatca tcttggactt
    27661 tctacatgtt actaatgagc gtgtaaaaga acgagatggt gtttttattt ctatcaatga
    27721 agctcttttt ctttgcaatc ctcacttcaa tcctctataa tgtcgcatat agtttagtaa
    27781 atgagtaaac tactaattta cttatttact aaaaataaaa ggatgaggag ttaaaataat
    27841 ggaaatacca acaaatttaa aacataaacc agtaatcgtt gtagaagact atgataaagt
    27901 tgatggaaga aatgcattaa atacggatgc aaaagggctt tcactgggcc ttgctcagtg
    27961 gaatgatcgt ggaaaagtcg atatctcagg caaggtatgg cgacatactg gagaaaaatg
    28021 gtcacgacag tcggaagaat taccaatcac acgtatttta gatttagcga tcttagctgc
    28081 acaaggaagt ttatacttcc aagatgctta tcgttatgaa aaattttatg atccagaaaa
    28141 tccagtcgta gacatcattg gattacaagg gaaccgaatg acggtagaag tagataccaa
    28201 aaatccaaag atcgatgaag acatcatttt gtattacgat acactacaaa aagacggaga
    28261 actgattggg gaacgattcc gtattttaaa acgtctttta gatgagctag gatattaata
    28321 gacagagatg atcaaaaggg gaagagaagc atggagaatt tctcactaac agaaaaccga
    28381 accttttcac ggctagaaaa gcaaatgatc tggaagaaac cgaaaagcca tcggacaagt
    28441 gcagaagaat ggcggatcgc ctccgaaatc aaagggaatt ggcaagatcc tgaaatgaaa
    28501 atcagtaacg tacttttgga aggagatgcc gggtcgggga agacacaatt agccaaagca
    28561 ctatctgctg atctgcaact tccctataca aaagtgacct gttttgcaga tatggacaaa
    28621 tcagatgttt tcggagcctt attacctgta gtagattcta ataaggaaca agaccaagaa
    28681 ttactagaag ctatttacca aacagataca cttgaagctg tactgacact gatccagaac
    28741 cattacggca ttgatccttt ttctgctaaa gaaaaattag cagagctagt tcaaaggatc
    28801 gaagctgatt atccagatgc aatccattac agctattacc cttctgaaat cgttcgagcg
    28861 attgaaaaag gatatttatt agagattcaa gagccgactg tcatccgaga tgcctctgtt
    28921 cttgtggcac ttaactcagc gctcgaacca aatgggatgt tgaatttacc gacaggaatc
    28981 attcgtcgcc atccagattg cgtcattgtg atcactacaa atcgaaatta ccaaggaaat
    29041 cgcccattaa atgaatcttt aagagatcgg atgcaacatg cggaaaaaat ggatcttcct
    29101 gccttagaag tcatggcaga acgtgcgatg gcgaaaacta tgatccaaaa acaagaactt
    29161 ctcttaaaga tggcagagat tatccgtttg ttggatgaaa ctgcaaaagc taacgccatc
    29221 aaaggtgtag caggaatgcg ttcttatttt tattgggcaa atacctataa gcaaggacaa
    29281 gatttactcc agtcgattta tccaaaagtt ttgtataaat tatccactga ttcagatgaa
    29341 ttggcaattc ttgaacaagc tttgtctgac agtggattgc tactggaact tcaggacata
    29401 ttgagaaaag aaaaatgggg tcatcctcaa tctgagcata caaaaggaag aaccattagc
    29461 gccgaagaag caaatgaacg aaacatcact gaaaatgctg aagaaattct gcgcttagat
    29521 gaaaagaaat cgttgtctgc tgaagaacca aatgagggag aagagaaaca agaagaaaca
    29581 atagaaaaaa acgagattcc tcctcaaatg caaaaagaac gcagtagcga tatcgaagga
    29641 aaaaatcaaa aagaacaaca aacaggagat gattctcaag aaatgtctgc ttctgacatg
    29701 gaagcacatg ataaggaaat caagaagcaa ctgaataaag aagcgcgaca aatcatgaag
    29761 gaaacgattc atgaaaaaga aggtctcatc gttcaccgac cagctttcca aggaaaaacg
    29821 ccggaagcac gtgagctaca catgcaagta atgccaatag tagaatcact tagccggcaa
    29881 attttagagt tactggataa tgaacaaaca gagacgtacc aaaaaggaaa atacgaaggt
    29941 cagcggttca atgcaagcaa agtagcatat ggtgatttga gaaattttga caaaaagaac
    30001 ccgccacatg agcaaccttc tttagcggta gctgtacgga tcgatgaatc tgggtcaatg
    30061 atacgggatg atcggatcga agcggcaaaa aaagcagcga ttgccattgc cgaattttct
    30121 aagaaagtcg atatcccatt gttgatttac ggagatacag cagaccgttc gtcaagagaa
    30181 aagacttctt tgttttctta taaagaattt gaagacggat ttcaatggtt aaatgaaaaa
    30241 ttagtcacta tgaaaccaag gcaaaacaat cgtgatggtg ctgcacttcg tttagcagca
    30301 gaaaaattaa acagacaatc cgcaacaacc aaactgttgc ttaatattag tgacggtcag
    30361 ccaaaagcgt tgccggatta tacaggcaaa aaagcaaaag aagatatcca gtctgttttg
    30421 aaagaatatg aacgtcaagg aatcctattt gtctccgcag ctattggcca agacaaagaa
    30481 gaaatcaagt cgatctacgg tgaaagtcgt tttgtagata ttactgactt gaatgaattt
    30541 cccaagcaaa tgattcaact gattgcccgc tatctatgat aaaataaagc tcaacgaacg
    30601 cacttagcag attcgttgag cttttcgttt ctagttaccg gtaacaagga tacttctaaa
    30661 atagaatcgg ttataatcaa gagggaccgt taaaggagtg aaacgatatg atacaagaac
    30721 aaaaatggtg gaaagaagca gtaggctatc aaatctatcc tgctagtttc aaagatagca
    30781 atggcgatgg tcaaggagac atcaatggga tccgtgaaaa acttaattat ttgaaagatc
    30841 ttggtatcgg ctttatctgg atcaatccga tctatcaatc tccatttgtc gataatggtt
    30901 atgacgtaag tgactatcaa gatatagaag agagattcgg aacgatggaa gattttgatt
    30961 tattgctaaa agaagcacat gaattaggga tcaaagtgat tatggatctt gtcatcaacc
    31021 atagttcgga tcagcatcaa tggtttgaag aatcgaaaaa atctaaagaa agcccgtatc
    31081 gcgattatta catttgggtc gacggggtag atggcaaaga accgaataat tggacatcga
    31141 ttttcggcgg ttctgcttgg gagtattctc atgaaactgg acagtattat ctgcatgttt
    31201 ttgcaaaaga acaaccagac ttaaattggg aaagcgagaa attgaaagaa gaactattca
    31261 atatgatccg atggtggttg gataaaggga tagatggatt tcgtttagat gcgatttctc
    31321 atgtaaaaaa agatgaatat tcagtaaaag ccacagagaa ccctttctca ccctttcaaa
    31381 atgtctcagg aatcgaagaa catttgaccg atttgaaaca tgtttttgaa gagtacgata
    31441 tcatgactgt cggagaagca agtggtgtca ctgcagaaga aggaccacaa tgggtaggga
    31501 aagacggtta tttcgatatg atattcgaat ttgatcatat ccatatctgg cagcaagaaa
    31561 aagaagggca attagatgtc cttaaattga aacttgcatt aagcgcttgg caaacttcat
    31621 tggatggtat cggatggaac gctttatata tggaaaacca tgatgttcct cgtgccgttt
    31681 cagtgtttgg agatactcgt cccgattttt gggctatgtc tgcaaaagca atcgctatga
    31741 tgtatttctt tttgcaaggt acgccattta tttatcaagg acaggaaatc ggaatgacga
    31801 atatgccctt tgaatcgatc gatcaagttg atgcagtaga ttcgaaaaga ctttataaaa
    31861 ggctgcttgc ggaaggtaag acaagagaag aagcattgga tatcattcgt gaaacaacga
    31921 gagacaacag caggacaccc atgcaatgga cttcggaaca atatgctggt ttttctacac
    31981 atgaaccttg gctgatcact aatccaaata ccaaaacgat caatgtagaa caacaagaat
    32041 atgaaccaga gtcggtcctg caattctata agaacatgat ccgcattaga caaaccaata
    32101 aaggtctgat atacggttct tataaagaat atcttcatga acatccacaa ctttatgtct
    32161 atgaaagata tttagaagat gaacaatatc ttattatggt aaacttaaca gaatcacttg
    32221 ctgactatga acttccaaaa gaagcagatc agtcctggac attactcttg tcaaattcct
    32281 ctagcggaga atttgaagct aaaggcatac tagcacctta tgaagctcgg ttatataaaa
    32341 caaacaagta aaacttcctc gttaaagttc attagttgga ctttgcgagg aagtttttca
    32401 gattgctctg tcaattactc atttcaataa ttcgctctag gaccaccgat atatttagga
    32461 cgagagcgaa gggctgtcac gtgagcttgt ccaagggttt tcaaacgagg tctgacaggt
    32521 acttggacat gtttgatatg cataccgatt gatgtgtcac cgatatcgat accggcttgt
    32581 ccaactacgt gttccacttc gacaggatca ttgaactggt caaaagcagc aacagaacaa
    32641 gcacctccag catgtagtgc aggaacaaca gagacaattt cgaaattttt tgcttctgcc
    32701 actgttcgtt ctactactaa tgctcggttc aaatgttcac aaccttggac agctagcgca
    32761 atttctttag gatccaacaa ctcttttaac gtacggatga tccattgacc aacttccgca
    32821 ctggaatttt ttccaatatg tcctccaacg acttcgcttg tgctgcatcc taaaacaaaa
    32881 agatcacctt ttttcaagtg tgcctcagcc aatatgtcat taactatttc agtcaattgg
    32941 tcttttaatt ctttttctga caacttcatt ttctaaaacc ttctttttca attaatattg
    33001 cttccgtgct tgaatacgtt gaagacttgc agttatagga aaggcaagtc ccattccaat
    33061 cagattttgg aagatgtttc ctggtataga agccactcca gccggccaat catataaaat
    33121 ccaaccggcg ataccatagc cgatgatcat aactaagctt cctaataaaa gccctaatcc
    33181 ccacatacga gtagaagatt tgctgaaaga accagcaaca tatccttgta acccgtggat
    33241 cactaatgaa aaaactgccc actgcggata tcctgaaatc aaatcgatca atagaccact
    33301 ggaagcacca acaactaatc cacccgttgg accataaaga aaagcagcgg tatagatccc
    33361 ggcctcgcat aatgtcacaa atccattcgt agccggtaca gggatcaaaa ttgttaatga
    33421 aagggcaact gtcaacgcaa tcagcatagc atagatcgtt aattgcttag ttttcatttc
    33481 tcattcctcc tttttgaata ccgccagacc agacacttcc ggtatgatcg ttcatcagca
    33541 cgccattaga aatacaatgg gcaacaaatt ttttactttc tgctactgct ttggtaaaat
    33601 ctgcccctaa cacaagattc gctgttattg cagaagaaaa ggcacaaccg gccccgttta
    33661 ctgttgtagt gtcgattttt ttatgagaaa atacctcata atgatcaatt gaatagagaa
    33721 gatccacagc ttcatctcca gccatccttg tgccgccttt gatcacaatg ttttttgttc
    33781 ctgaagcagt gagttcttta gcgagatgga tcatttctgt taacgaagag ggaagagctt
    33841 gaccagaaag taaagcagct tctgccaaat taggcgtaat catcgtaaca agtggaaaaa
    33901 gttcttcgat gagctgcgaa atatacaatt gattgatcac agcttcagtt tctttgaatg
    33961 ccaaaacagg gtctaaaatg attgggatat tttgttttgt ttttatgaag tctcgaacaa
    34021 ccatgattgc ttcacttgaa ttcaataacc caattttgat accatctaat gaagtcattt
    34081 tatcaatcga aactaactgt cgtttaagca attccaaaga tatagattcc agcataaatc
    34141 gctcattaat atctagtgcc cctatagaag tcaaggcgct tagtccgaat agaccaaaat
    34201 tctcaaaagt ttttaaatct gtttggattc ctccaccagc aaatggatca gaaccgccaa
    34261 ttgtcaagat tcttttcata acattttcct ccatgaataa gagtataacg aaattttcaa
    34321 aaaagaaaaa cagccaattg gcatattttt atctcatcca atttaaaaaa acaaaaagaa
    34381 aagaaagacc aaaatggatc tttctttcct taaatagtta ggacttttgt gattttaatt
    34441 ctttctcgat ttgaagccgt tgcactttca ttgtagctgt tcgcgggatt gcatcaaaat
    34501 cacggatgat agggacgttc aagcgaggaa gttcatggac ttgctcccac catcgattcc
    34561 aatccatttc tttatcagga gctaaagcaa taatcggttg tggagaatga tttttatccc
    34621 ttacaatcac tacttctgcc aaaaaatcta acgaatctaa taaaaagtct tcaatagcta
    34681 atgtactatt gatcgtttcg atcaaatcca cttgccgatc tttcaaaaat aggtggccat
    34741 gcttatccat aaaaccgtaa tctccgctat cccaccaatc gccataaaca ttttcctgga
    34801 accgtgcatc ttccttgtaa taagtcaaag cccgtccttt agacagtaat tgtatatgac
    34861 catctgtgtt ttcaggtagg acattcccaa ctgaatctgt aatccgagcg cttgtcatgt
    34921 cttccagtcc aacgcccata tctcttgcat cacttgtttt caaactctct agtgtatgag
    34981 ccttaagaat cattggtccg cattcacttt ggccatatac ttgaagaaat accgcatcct
    35041 gtgccatcga cgttcgcaaa aatgtcttca ttgtctggtt gtttatagca tcaaaagtgg
    35101 agtgatagta tcggataccc gaaaaagctt ctggatgctc cttagcagta aaacgccact
    35161 gaacaaagtt attcggatgg gtctctagtg caattggccg gtgagcttcc aacatatgaa
    35221 caacttttga actttgtgcg tttgctaaag gcatcatagg aaatcccatg gacatcaaag
    35281 aagagatacc aatattgaat ctggaatgca ctggagagat gtgaaaagcg attaatttct
    35341 tttccgaaat ttttgtgaaa actgtttttt gccatttcgt ccgccatccc atagaatgag
    35401 cagaatgaca aataagttta gggataccag ttgtaccaga agtatgggtc atataagaaa
    35461 tttcattttt gtctaaaaat gattgagaaa cagacaaagc aggttgttcc attaaataaa
    35521 gaataggaat acccgtggtg ctagttaatt ttaatatcct aaagaatatc tcaaagttcc
    35581 ttcaaaacgt cgttgtgctc gacttaatag aacactgtaa gccagtaata tgctttcaaa
    35641 tctactctct agccctttaa cagaacgtga gttgaaattt tgacaaccta atttttctaa
    35701 ggaagaa
//
LOCUS       DADVXE010000022        34771 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.022, whole genome shotgun sequence.
ACCESSION   DADVXE010000022 DADVXE010000000
VERSION     DADVXE010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.022"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(227..1114)
                     /locus_tag="KB913_001208"
     CDS             complement(227..1114)
                     /locus_tag="KB913_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6819581.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1111..1980)
                     /locus_tag="KB913_001209"
     CDS             complement(1111..1980)
                     /locus_tag="KB913_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6819582.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2117..3403)
                     /locus_tag="KB913_001210"
     CDS             complement(2117..3403)
                     /locus_tag="KB913_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6819583.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3676..4254
                     /locus_tag="KB913_001211"
     CDS             3676..4254
                     /locus_tag="KB913_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6819584.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4254..5183
                     /locus_tag="KB913_001212"
     CDS             4254..5183
                     /locus_tag="KB913_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6819585.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5180..6916
                     /locus_tag="KB913_001213"
     CDS             5180..6916
                     /locus_tag="KB913_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6819586.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="KB913_001214"
     CDS             complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="KB913_001214"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBB6819587.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7812..8321)
                     /locus_tag="KB913_001215"
     CDS             complement(7812..8321)
                     /locus_tag="KB913_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBB6819588.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="KB913_001216"
     CDS             complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="KB913_001216"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBB6819589.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9622..10713)
                     /locus_tag="KB913_001217"
     CDS             complement(9622..10713)
                     /locus_tag="KB913_001217"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBB6819590.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="KB913_001218"
     CDS             complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="KB913_001218"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBB6819591.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="KB913_001219"
     CDS             complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="KB913_001219"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBB6819592.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="KB913_001220"
     CDS             complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="KB913_001220"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBB6819593.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14676..15650)
                     /locus_tag="KB913_001221"
     CDS             complement(14676..15650)
                     /locus_tag="KB913_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBB6819594.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15631..17514)
                     /locus_tag="KB913_001222"
     CDS             complement(15631..17514)
                     /locus_tag="KB913_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBB6819595.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17532..19757)
                     /locus_tag="KB913_001223"
     CDS             complement(17532..19757)
                     /locus_tag="KB913_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBB6819596.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19872..20906
                     /locus_tag="KB913_001224"
     CDS             19872..20906
                     /locus_tag="KB913_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6819597.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20973..21986)
                     /locus_tag="KB913_001225"
     CDS             complement(20973..21986)
                     /locus_tag="KB913_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6819598.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22064..22252)
                     /locus_tag="KB913_001226"
     CDS             complement(22064..22252)
                     /locus_tag="KB913_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBB6819599.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(22692..22820)
                     /locus_tag="KB913_001227"
     CDS             complement(22692..22820)
                     /locus_tag="KB913_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBB6819600.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="KB913_001228"
     CDS             complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="KB913_001228"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBB6819601.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(24307..25362)
                     /locus_tag="KB913_001229"
     CDS             complement(24307..25362)
                     /locus_tag="KB913_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBB6819602.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="KB913_001230"
     CDS             complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="KB913_001230"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBB6819603.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="KB913_001231"
     CDS             complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="KB913_001231"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBB6819604.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="KB913_001232"
     CDS             complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="KB913_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBB6819605.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(28682..30718)
                     /gene="ligA"
                     /locus_tag="KB913_001233"
     CDS             complement(28682..30718)
                     /gene="ligA"
                     /locus_tag="KB913_001233"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBB6819606.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(30735..32969)
                     /gene="pcrA"
                     /locus_tag="KB913_001234"
     CDS             complement(30735..32969)
                     /gene="pcrA"
                     /locus_tag="KB913_001234"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBB6819607.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            33124..34683
                     /locus_tag="KB913_001235"
     CDS             33124..34683
                     /locus_tag="KB913_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBB6819608.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
BASE COUNT         9518 a         7494 c         6336 g        11423 t
ORIGIN      
        1 gacaatcagg acagtcatcg gcaatatagc agcaatcact tctttaaaat tttttagcat
       61 gtatcctcct cctttactct ttaagtttac cttaaaatga aagagttttc gagcacaaac
      121 ttaaaacgtt atcatttaat ttttctcaac ataaaataac acacgtccca aaagtatctt
      181 tttacttgga aaaatgactt tgaaggaacg cgcttattgt gtttttttat tttacagagc
      241 cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa tacgatggca gttggtaaag
      301 tagcgatgac taatccagcc atgatcattc catagtctgg tgtataggaa gcacccatag
      361 cagataaaac aagcggaacc gtccgtttat caggagattg caaagctact aagggccata
      421 aataattgtt ccagctactc atgaatgtga tgattgcagc cgcggcatag gtatttttag
      481 ccgtcggcat atacactcta aaaaaaatac ttagttcttt tagaccgtct aatcgagcgg
      541 cttctactag atcttttgga aaagatttaa cattttgtcg aaagaagaag atcaaaaaag
      601 cagtgctaac agatggcagg atgacaacca agaaactgtt gattcccaaa accgttccgt
      661 tcaattgtga aaacattcga tataaaggga tcatcaatgc cgcaaaagga accatcatcg
      721 atagcagtag aatattgaaa attaggtctt ttcgtttact ttgataaatc tcaaatccat
      781 atcctgccat tgacgaaatc agcaatgcaa acacagtggt caccaaagcg atcatcgctg
      841 aattccaaag ggaacgagta aaattcagct cattggaaaa caaattttga aaattgatga
      901 tcaagttact gccaatcttt atttttcccg atgtgatatc cacgggtgta ttcgtcattc
      961 ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga taggatgctt aatgctgtat
     1021 actttaatac tgacccaatt gtcgaacgaa gttctaatgc ttgttttttg acgttggggc
     1081 gttcgattgt ttctttttct accatatttt tcatcgactt tctcctccta ctttcgtttg
     1141 gattatcgac aatatcacaa taaaggaaac aataacaaag gaaactgctg ccgcatatcc
     1201 aaaattaggc gtgaatttat aactcaaatt atagatgtat tgagataggg tggtcgttgc
     1261 atttgctggt cccccgccag taatattttg tacttcatca aaaagctgca atgtcccgat
     1321 cgtcgaagta atggaagtaa acaaaatgat tggttttaaa tttgggatcg tcactttgat
     1381 aaactgctgc catttagaag caccgtcaat agatgctgct tcataaatct ccgaatcaat
     1441 attttgcatg cctgaaagga aaaaaatcat attgtatcca gtccaacgcc aagtgatcga
     1501 aagaatgatc agaactctcg cccaaattgg atgagtcaac cagccaatcg gtgtgtcaat
     1561 cataccaatg cccaacaaca agttgtttac aaggccagat tgagaaaata gacttttcat
     1621 gatcagagaa taactgacca tcgaagtgat acatggaaga aagatagcgg ttcgaaacaa
     1681 ccctttatat ttcaactttt tatcatttaa aaggttggaa ataaaaagtg ctagaaacaa
     1741 catgatcggt acttgtacaa gtaaatacag gaatgtatta aaaaaagctt ttttaaaagt
     1801 tgcatctgtc aacatccgct gataattacc taacccgtta aatgtcatat tgacaggggg
     1861 accactttga aaagacgtga tcaaagccaa aaccatcgga ataaaaacca tgattgatat
     1921 caaaatgact ggcaagatta aaaaagcatg cccgtttttg aataaatctt tctgcttcat
     1981 tcttttccct ccaattctat cattgattat ctacatgaaa agacaagaaa gacaatatct
     2041 gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg atgaaaaagc gaagaaattc
     2101 acttttttac caccgatcaa ttagccaatt gtgcttctac ttgtttttgt gtatctgcta
     2161 gtaccttgtc tgtctcttct ccattgatga ttcgatgaag agcttcagct acgactgctt
     2221 caattgcata ggtctcatgt ccgtaattca cttctggtat ttcagatgtc catgttgaaa
     2281 aatcgtcaaa gatcttttga ccactgtaaa attcagaagc ttcttgataa gcttcttgtt
     2341 cattcgcgct aagcatcgta gatactagtc cgatttcttt cgcaagagtg cccatcagtt
     2401 cttcattcga agcaaacgtt gcttctagga aatctttcgc tgaatcttct ccagctactc
     2461 ctttgatcac ataccagcca gcgccgccaa ggttagaagc ttgcgctttt tgcagatttt
     2521 ctggaagtgc aggtattggt gcaatcttcc attttccaga ttggttttct gctccttgga
     2581 tcgttgaaga ataccaagcg ccagttgggc tagaagctac tgctcctgat tgtatcgcag
     2641 ttactccagc attccagtca gaggtttgtt cgactagatc ttctttcaaa agagtggcaa
     2701 acaattcaag accatacttt aaagatgcat tgtcttggat cgtgactgtc tccccatctt
     2761 cagatgtata ccattctcct gcctgttgca taatcatcct tactcgacca aggtcagaag
     2821 gattgacttc agcgattttc tttcccgtct tttctttgac atctcgcgct acttgaatat
     2881 actcgtccca cttcagattc tccatatcct cttctgtata acctgcttct gccatcagat
     2941 ccgtacgata gaagtttgct gttacgcccg aatcgaaagg aacaccgtat attttatctc
     3001 ctactttgtt taccgcaaat ttatacggtg caaaatgatc ttcctttaca atagcagaca
     3061 aattagcgaa tgcatctgga taagaagtca aatagccttg tatcctataa tcttcaatca
     3121 agacgatatt gggcaatcct tctgtattcc cgctcgctaa agcggtgttc agtttctgaa
     3181 cgatatcatc ctgagacatc gtaacaactt ctatctctgt ttcttcgttc tcataaactt
     3241 tttttgcttc attcactgct ttgatattga atgtctcatc ccacgcccag acagtgactt
     3301 tttcttcttt gtctgctgta ctactagcac ttccgcatcc tgttaagaaa cctgatgctg
     3361 ccgctaaaca aacgactcca gcaattaact ttctgatgtt catttttatc cgctcctttt
     3421 ccatccatta gttgtttacg tttgctacat tcatcatacc aaaatttgaa aacggtttct
     3481 ttattattca gatacttcaa aaatttctcc taaaataata aaaaaataca aatcaactat
     3541 gacaaaagga ataatcttag catctagacc aaagatcgaa atggtgaggt ttctttaaaa
     3601 taaaaatatc cttgcatttt ctcctagaaa taagtatttt taaattacaa gactattctt
     3661 aaggcgggta aaaaaatgcc aatacgcgta attcttatcg atgatgaaca gacgatttta
     3721 gatggaatga aacagttgat caattggtct gagcacgggt ttcaattaat agggactttt
     3781 tccagtccgc tgaaagcgct tgatttttct ttggtacatg caatcgatat cgtggtcaca
     3841 gatgtaatga tgcctgaatt aaatggaatc gaattatcgc ggctattaaa acagcaacaa
     3901 cctgaaacac agatccttat cctctctagc tatgatgaat ttgatatggt taaagattct
     3961 tttaaagaag gcgtcgctga ttatctttta aagcctcgat tgagtcctga tttttttcta
     4021 aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc ccaacaaaag cccaatcacc
     4081 aatcgttatg agcagatctg cgagaatctt tcacagcaga ttgctggaca aactcgtcca
     4141 ttgcttgacc ctcttctttt tgaacacacc ttgtttttct gttatatacc gaaaaacggc
     4201 cattcagttc aaaacaaggc tctaaacaaa aacagtcgat cacccattca ttgatggata
     4261 gcgacgattc gtttactatt tatcctgttt ctaccttttc ggaagaatcc ggctatgtaa
     4321 tcaatactga ttccaaagat acacttagga agtttgttca aaagtttcgt caagaagttt
     4381 ttccaggtga tttttttgtt gtttctgatt cttttgcaat ccaagatatc aatgaaatat
     4441 tccaagagat cagaaattgc accaaaggac aacgtttcta tcataaggga aagaaccttg
     4501 cttatcagca tgaacttctt ccgttattaa ccaaccacga gcagcaagca agtagttatt
     4561 taacaaaaat cgttcataaa gactacgctt tagctgtcaa agaacttgag aatttcttca
     4621 cgacgatatt ggaacagcct attgatccag cttatttgaa acatgaggca atcaatcgtt
     4681 tctatgcatt actcaacgct ttggctgacg agcatgttgg gaatgaagaa ctttctttgc
     4741 tcaagatcgc ccttccttct ttattagccg atgctgagta tttcgaagat ttttctattc
     4801 ttgtcaaaga aacacttgag aaactcaccc acttttctgc aaatgcaaaa aaagacaatt
     4861 tcgatatctt gactttgatc tacgagttcg tccaggaaaa ttatgagaaa gaaatcaatt
     4921 tacaactttt atccgaaaaa tatcattttt catatagcta tctctcagcc atctttactg
     4981 aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt ccgtatcagt aaagccaagc
     5041 tctttttgac ggaaacacgg cttactttga cggaaatctg tgagaaagtc ggctataccg
     5101 aactgggtta tttctccaga gtttttaaag aagagacagg aatgacacct tctcaatacc
     5161 gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag catgaactct ttgccaaact
     5221 tctgttcatt ttgttcatcg gtctttttct gcaagccatc gtcatttctt tgtttattta
     5281 tcatcgatca agggatgcct atatccagct gttcaatcaa tcgaatgatg tggtactaaa
     5341 aaagattcaa tctgaatttg aaagtttgaa tgatacaatc gagaatacat tagccgcttt
     5401 tgattctaat ccagctgtca aaagctattt ttccaatgat ccagcccaac atatggaaca
     5461 gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct ctttcaaaaa tccatccaat
     5521 gatcgattac gatgtattga tctttggaga aaatggaaga acttttgtcg gaaacgacat
     5581 gctcactgcc gtatctgccg attctttttt tcaatctgcg attgctcaga gagtgaatga
     5641 acgtgctgct gatacacaaa tgctttttgc acaccacgga ttgactcttc gcgataagaa
     5701 agcacccagc gtcttctttg tcaaaaaact gaaaaataca ttgaatcacg tttacggata
     5761 tgctgtttta tcgatctcat ccaagcaact agcgaatctt tttcaatctg tagtaaatcc
     5821 tgagatatcg aagatctcct tcatgaacga agaacagacg atcatcgcat caaatgaaga
     5881 aaatacaatt gggagccgat caatgatttt caaaaaacta acagtaggtg aaacaacgat
     5941 ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc caggattgta cattactcag
     6001 tcaagtcgat cttcattctt tatctaacca aatgggcgtg atttttccga ttattttgta
     6061 taatatcgtg acacttgctt ttgctggctc attggtattt atgtatttgg atcgacacac
     6121 aaaatcgatc taccgcttga ttgattcgct aaaacggcta gaggaagatg gcttaaaagc
     6181 tactgttcct gtacaaggaa gccatgaagt ccaattgcta gggaatacga tcaatcaatt
     6241 gctaagtaat gctcagcatc attatgaaca gacgatccaa gacgaaaaga agaaacgttc
     6301 gcttgaaatc caaactatgc aagcacagat acagccccat tttatttata atacgctgac
     6361 tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa gcagttcaag gaatcgacag
     6421 tttcattact ttactaagaa gtacgattgg gaaaaaagaa gaagtgattc cagtcaagga
     6481 agaaatcaaa agcgtacaaa gttacatcga tcttttgagt atgcgatatg gcgaaagaat
     6541 ctcggctaaa ataatgattc ctgatgaact gcagtcatta tctatgccga atatgatcct
     6601 tcaaccaatt atcgaaaacg cctatcttca tgcttttcac aataaaacgc aaggattcat
     6661 cacggtgtac ggcaaaacaa aaaatcagct tcttttattc gaagtgattg ataacggcga
     6721 tggcttcgat actgaaaata ccaaacaaaa aaatgatcat ttttcaggaa tcggcatcag
     6781 ccatgtagat gagcggatac gcctaatgta tggcgatgca tatggcttaa cgatccaatc
     6841 agtgattggg acaggaacga ctgtaacgat ttgtctaccg cttcttccta aaaatcaatc
     6901 agaatatcaa aaataaagaa tagccaagcg ctgatttttt tattttaagt taaataaatc
     6961 aatcagtatt cttgactttc atctacgcgt ctcttctact gtcagcactg gataacagcc
     7021 caatatttga ctttctcctc cgagcatctt gatttcttgg agcgcattct ctactaatgt
     7081 cattggacgg tccaacaaca aatcgatcac gaaaaaatat tctcccaagc tagttttcaa
     7141 tggtcgggat tcaatcttac ttaagttgat ttcccgccag ccaaaagctg ccagcatttt
     7201 atgaagcatc cctggccgat tagcaggtag tgtcaagatg acactcattt ttactggagc
     7261 tgactgctgg ctggtcatct ttcggtcacc gacgatccaa aaacgtgtct ggttcaactc
     7321 attatcttgg atattctcag ctaagatctc caatccaaca tgctgtgctg tttctaatga
     7381 agcaatcgct gctgcgtctt ctttcggatg ttctgctaca tacattgctg cagcagttgt
     7441 tgattctgtt gctactaaag gaacattagg ataatgcgtt tctaaaaact gttgtgattg
     7501 tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt gttgctggat tgcctaaaag
     7561 ctgctgcttg ataggaagaa cgatttcact tttaacttcg acttctggat gtttggaaag
     7621 aagatcgatt gtgtgatgaa cagctccttc caatgaattc tctacaggaa cgacagccag
     7681 atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg atggaagcat acgcagtcaa
     7741 ttgttctgta ggaaatagct gacaagccgc ctgataagtg aatgaacttt ctggccctag
     7801 atagctgacg ttcatatgct tttgatcctt tctataatgg tatcgatgat cttttctggt
     7861 gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt cataccaaga aagtcgttgt
     7921 gccaataatg cttttatttc ttctcttgtt tttccaagag ctaaaggtcg aatagacgtt
     7981 tcatcttgtt ggatacgatc aactagacag tccgcttctg cctctaagta aagaacaatc
     8041 ggctgtgttt ttaaaaaacg ccgattttct gcactttgga caatccctcc accagtcgcg
     8101 ataattttgt cttcatttga cagctttctt aaaatatctg actccacttt tcgaaagctt
     8161 ttttcaccgt aatagtgaaa atattcggca atcgacaatt ggatatgttc ctcaatcttt
     8221 gtatctaaat ctacatactc tttttgtaaa cattgagcta accctttacc gattgttgtt
     8281 tttccagcgc ccatgaaacc aatcagcaaa atgctagcca tgagcttctc ctcctgacac
     8341 aagttctgct aaatcgtcaa aaaatgccgg ataagagatt gaaacagctt cagctccttc
     8401 tagttcgcaa ggtccatcag ctatcaaagc agctacttgc agcatcatac cgattcgatg
     8461 atcgcctctg ctggacactt ttgcgccatg cagaggtgtc ggcccatgga tgatcagacc
     8521 gtctgctgtc gcttttatct ttgctcccat tttctgtaat tcttctgcca ccgcatcaat
     8581 tctgttggtt tcttttactt ttaattcttc tgcgtctttg atgatcgtga ttccttctgc
     8641 ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc agacgcggaa tgatttctcc
     8701 accaatcgtt gctttcttca aatgactcgt cttgacactt aaatcagccg attggttctg
     8761 ttcattgtga ttcgtctggg taatcgctgc gcccatctcc tccaacacat ctaagatacc
     8821 agttcttgtt ggattgaccc cgacattttt taacaacagt tggctttccg gaacaagaag
     8881 tcctgctgct agaaagaaag cagctgatga aatatcacct ggaacagtta tctgttgacc
     8941 agttaatttt tgcggtccgg tcactatgat cgttttatct tccactgtga tccttccgcc
     9001 aaattgacga atcatttctt ccgtatggtt acgggaacgt tctttttcaa cgattacgga
     9061 tgtgccttct gcttgtaatg ccgcaaacag caaagcagat ttgacttgcg cactggctac
     9121 aggcatattg tatcggatag gtgataaaga gcgggttcct gtcacagtga ttggtagata
     9181 ctggtcattt tcttctcctt gcaagtcagc gcccatctcg cgtaaaggtt ccatcactcg
     9241 ccccattgga cgtttagaca acgaagcatc cccgaacaga gtagtcgtaa aaggctgtcc
     9301 agccaaaata cccatcaata aacgtatggt cgtaccggag tttcccatgt caattgattc
     9361 ggttggttgg acaaatgagt ggctaccgcg accatgaatc ttgatcacct cttcctcttc
     9421 ttcgatctcg acacctaatt gttggaaggc atgtaaagta ctcagacaat cttctgcgcg
     9481 caaaaaattt tgtatagtcg tcgttccttc agcaattgct ccaaacatga tgctgcgatg
     9541 ggaaattgat ttatctgctg gtatcctaac agtccctctt aatccatgta tttgttgtaa
     9601 taattgcatt tatccagcct cctatttgat ccagcaatga taactggtat tagacataat
     9661 gattcttttt gcttgtaaca aatcctgttg gtttttaaaa ctgatttgca gtattcctaa
     9721 aatatcttcc ctggtctctt ggatcttcaa attaatcaaa gaaactcccg cttttccgat
     9781 cagtccagtt acttctgcaa taacgccagg ttcatctggc acatcgataa ataaatcaaa
     9841 aaaggcagga atcgcgcctt gcttatggac aggcaactgg tctcgacttt cttttgcccg
     9901 attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg atccattctg ctatttgtgt
     9961 catttcttgt tgccaatctg ccaatcgttc caataatatc tgcttattgc tcaacaaaat
    10021 atctgtccac atgacaggat ctgaggaagc gatcctagtg atatctcgaa agcctcctgc
    10081 tgccagttgt ttggctcgcg gatactcttg attgaattgt tctgcctgat tgactaagcc
    10141 agctgccaga atatgtggaa aatgacttag cattcctgtt atacggtcat gttctcttgc
    10201 tgtaagagtt acatattttg ctttggttcc gcaaaatagt tcttgcagtt tttcaacatc
    10261 ttttttcgtc ttttccaaag gtgtaaagat gtaataggca ttttcaaata gtttagcatc
    10321 tgctgcctgt atacctgatt tatgagaacc agccattgga tgtccaccga caaaccgaag
    10381 atttttctgc tcagcggatg tcacgacttg ctgcttcgta ctgctgacat ccgtaatgat
    10441 gacgtgatca gacaagttga ttctttcaag gacatcaaga taagctaagg ttgtacggac
    10501 gggaacggct aataagataa cgtctgcttg ttctgcacct gtttcaaaat cacttgcaac
    10561 gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt tttgactgac tatcccaacc
    10621 aactactatc agttctggat tggtctgacg aatacaaagt gccatagaag caccaatcag
    10681 tccaagcccc acgataaaaa catgttgtgc catcttattt gccccctttt tagtaatgtt
    10741 tcaagtagtc acggtactcc ttcactgcag ctttcaactc aacaagcgaa tcacttggga
    10801 attttgacaa tagctctgtc gctaccacag tggctacaac attttccgca acgacgctag
    10861 ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc tttgtaaggt tcttttgtat
    10921 cgatatcaac actttgaagt ggcttgtaca atgtaggaat gggtttcatg accccgcgaa
    10981 tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc gcctagatta ttggtacgtc
    11041 ggaaatagcc tctttcttct tcccatagga tctcatccat cacttctgag cctggtaatg
    11101 aaccagaagt gaatccgacc ccaaattcta cgcctttaaa ggcattgata ctaaccacag
    11161 cttgtgcgat tttggcatct agcttcgtgt cccattgtac gtagcttcct aatccagctg
    11221 gaacgcctcc aacgagcact tctacaattc ctccgatcgt atctccattt ttctttgtct
    11281 gatcgatcaa atcttttatt ctttgctcaa ctgctggatc aacaactcgt acttctgacg
    11341 cttcagaaat ttctttgatt tcttgaatcg agatatttcc aggtatttct gcttggattc
    11401 caccaagaca aatcacgtgt cctgctacga tgatgtcaag ttcttccaga attttcttgg
    11461 caattgcgcc gattgctaca cgcatggtcg tctctcttgc agaggaccgt tcaagcacat
    11521 tccgaagatc tcgatgatgg tatttcatac cgcctaccaa atccgcgtgt cctggacgcg
    11581 gacgtgcaac tcgccgcagt gattggtctt tttcaggcac ttctgctaca gacatgacag
    11641 ttgtccaatt tttccaatct ttattttcta ccactaaagt gacaggtgaa ccaattgttt
    11701 tgccgtgacg gatgccagac gtgatccgaa cacgatcttt ttcgatcttc atccttcctc
    11761 ctctgccgta accagcttgt ctgcgagcga gttcgtgatt gatttcttct tctgacagag
    11821 gtaatcctgc tggtagtcct tcaataatgg ctgttaattc tggtccatgg gattctcccg
    11881 cagtcatata acgcatctta cagtcctcct aagtaatctt tgaatgtctc tgtgggaaca
    11941 ggaacgattt ttgcttgccc aatcttttct agcaagatga tattcaattg gcttcctctt
    12001 gctttcttat catgggttat cgcgtggaat aattcatctg gatgacttag atcgtacgta
    12061 atcggcagat ggaatttttg aagtatcctt tctaaagcag ctgtcgatcc agttggagac
    12121 aagccgattt tttctgcatg agaagtgatg gctaccattc caatagctac tccttctcca
    12181 tgactgacta ccccatatcc tgctgtattt tcaattgcat ggccaattgt atgaccaaaa
    12241 tttaaaataa gtcgatttcc ttggtcaaag acatcttctt ccactacttt tcgtttgatt
    12301 tccaacgtag cagtaatgat tggaacagca tgttccagaa gatctttttc gtctttcagc
    12361 tcgttcagct gtttccaaag cgttgcatct gctatagctg ctgatttgat gatttcagcg
    12421 attccttctc gtaaacgacg taccggcaaa gtttttagaa cctcaggatc aatcaataca
    12481 ccagctggct ggctaaatgt tccgacaagg tttttcgctt tgtttgtatt gactgctgtc
    12541 ttcccgccaa tactagaatc tacttgtgca agtagcgtag tcggaatttg aacgaaatgg
    12601 atcccacgca tgaacgtcga ggccacgaat gctgctagat cacccaccat tcctccacca
    12661 agtgcaagta tcccatcgct gcgggtaaaa tcattatctg ctaaaaaatc gtataactca
    12721 gctgcttgtt ctaaagattt actggtctca cccgccggta cgattgaaag gactggttca
    12781 aaattagctt gtctcaattg gaacatgatt ttttctgcat atagtggagc aacgtttgta
    12841 tcagtgatca cagctacttt ttgaggtctc caaatcgttt gaagccatga tccagcctgt
    12901 tctagtgcgc ctttttcaat atgaatatcg tatttttggt tatcaacatg tacagtaagc
    12961 attcgtttca cttctttctt ttaaaaagct ggaattaatc gagtgtctga atcttttcca
    13021 ttgcttcttt catgatcgca acttctttca tcatgcgtga gtaagtcttt tcattcaacg
    13081 attggggacc gtctgaccaa gcatttgcag gatcaggatg gatctctacg atcatgccat
    13141 ctgctccgct tgccacaccc gcacgagcca ttggtggtac aagttcccaa attcctgtac
    13201 catgacttgg atcaacaatc acagggaaat gagttaattt tttcatcaat gggacagcac
    13261 ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg aatcccacgt tcgataaaaa
    13321 tgacaggaga tttgtcttcg actgcaatgt attctgcagc attaagccat tcattgatcg
    13381 taccggaaat tccacgtttc aatccaacag gtttacctgt tttaccgaca gcagatagca
    13441 gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat atcgctgtac tcagccacca
    13501 tatcgatatg cccttcatcc atcacttcag taatcacttt cattccaaat tcatcagccg
    13561 cttgacggat gtatttcaat ccttcttctt ctaaaccttg gaaagcatat ggagaagtac
    13621 gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc ggctttggcc attcgcgcac
    13681 attctctgat ttggtctaat ccttcgatag aacaaggacc agccatcgtc acgaaactgc
    13741 cgtcaccaat ttttactccg tctacatcca cgactgtatt gccaggatgg aattctcgag
    13801 aagtcaattt gtatgtgttt aaaatacgca cagcattttc tactccttca tagcgtgtaa
    13861 atgctccttc ttgtaaactt cgcgtatcac cttttagtcc aatcactact cgttctgttc
    13921 cttgatcgat tgagactttg aatccttctt tttcgatatg atcgacgact ttttttattt
    13981 gttcttccgt tgcttctttt ttcataatta ctatcattgt ttttcccgct ttcttttgtt
    14041 tacttatcta tcttggctga ttttctctac tttttcaagg tggttttaca ttaattccta
    14101 ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc tttcctactt atgacccaga
    14161 taatcaacaa aaaaagatgt ccctgtagga aattgcctct acagtgaaca tcttcaacga
    14221 gccttaaaaa gcgctgcaaa aatataaaat agccactata gatgaatttc tctacgtggc
    14281 tgtaagtcgt gtttaaaaat ctttagccat catagataca aacctggttt gtttgtaccc
    14341 acgaagtcat gaatacaaac ctatctaaaa tagctaaagt aatacgtatt cagttttgta
    14401 agttttctag atttcataaa aaatcgctcc aaactgatgt aagaattgta cctagtatag
    14461 acataaaaaa atcgactgtc aatcattttt atgaaacttt ttttaatttt ctgatagtta
    14521 actttgtttt tcagaaaaat aacaattggt tttattgaag aaaatagtca tgaacaaaag
    14581 tatctgagaa cttttttact ctcttgttca tgacatatag aataaagcag ctttgtcttg
    14641 taaactccgt ttttcaaata ataatctaaa gattgctact gaataataaa gccgatttca
    14701 tggtcctctt cgctgctgat tcggtaaggt gactcaacat ccgctcccca gctattgata
    14761 cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg ttcgtctttc tggcggtagt
    14821 tcttctatat gtgttgcctg ttccagttct tctgctttga atggtaaagc ggaaaaagca
    14881 aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt cttgatcttt atccgtatta
    14941 tccaacgttt gatttcttgt tagttctacc catttcgttt ccatatgcat gccgcattct
    15001 tggggaacaa ggtatgggga aacggggagt cctgccactt tataaatacc ttcgacacca
    15061 ccagccatcc gatccggata tgtttcccct gataggcctt catactcaaa aaattttgct
    15121 ttcgttggca taatgaacct taaacccaat gcgggtaatt ccggtaatcc tttttgtcca
    15181 taataatgca tattgacaag cattttaccc tctccagcga tttggtagga aattgtcact
    15241 tgggtttttg gtactgtgtt gatttccagt gtaaaaatga tttcaaccgt ttcagcgtat
    15301 tcattacttg aatattgatt atttactgga gcaatcggca aatcgatctt tttattgtcc
    15361 accagtactt ctatttcttt gacttttgga tacaatccgg ctcctaacca cataccggat
    15421 ttaaatccaa atccgctacc tctgtcatta tcggtcgttg ctcgccaaaa aactggaagt
    15481 gtttcccggt atagccattc ttttccgttt ttattgagcg attccagtcc gcctcttgta
    15541 taagaaaaaa tataatgcgt attccccgat ttgacaccta atgtacagtc gccgaagacg
    15601 attgcaactt tttccgtatc catatgactt ttatttactg tatttttcat aataatatct
    15661 tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa acgatcccat tccctgagaa
    15721 ttcatagtca cttggtttat cgtcaaagtc accgccatag cgcatcactt ctctgcctgt
    15781 gattggatca gtcacttgga tcgcctgatc tttaaaatcc catatatagc ctccttggta
    15841 catttcataa cgatcaagca acgtcatgta agaatccatt ccacctaacg aattccccat
    15901 gtcatgcata tattcacata agatgaacgg tttttccgct ttattttcaa ggtagtcaat
    15961 gatctcttct ggtggcgcat acatgcagct ttttacatct gaaatcgaat cttcgaatgc
    16021 tggatttgga aaattccctt cataatggac aagtcgatcg gggtctactt ttttgaagta
    16081 atcgttcatt tgtcgaatgt tttcttccgc ataagattca tttccaagag accaaaaaag
    16141 aatacttgga tggtttttta atgtttcgaa attcgttttt gctcgatcaa gaacagccgc
    16201 ctgccactga ggtactgcac ctggtacgtt gtaagaaggc tcaaatgcgc ccattttttg
    16261 ccatgagcca tgggattcga ggttcgtttc cgccatcaca tggattcctg cttggtcgca
    16321 taaataatac caagtgatct ggttggggta atgagatgtc cgtacgccgt tgatctttgc
    16381 attttttatg atagccaaat ctttttccat atcttctata gtgatggcgc gtcctttttt
    16441 cggatgccac tcatgtcgat ttaccccgtt gataatcatc cgttttccat tgaagtagat
    16501 gattttatct ttgatttcga ttttacgaaa accgaaggaa tagtcaatat actccgttac
    16561 tcttttttct tcgtctatcg tctccaattc aagcttatat aaattgggct gaaaatgccc
    16621 ccacagtgcc acattttcaa atccatcgat gcgaatcgtc atttgctctt ttaacggata
    16681 ttgctgttga tagatttcct tcccatcagg atctagtatc gctacattca gctgactgtt
    16741 tttggctact tgctcaaaag acaaatctac ttcaagtttg ccattttgac atttgtcatc
    16801 taagcgaggt ttgatccaaa gatcttctaa atggttttgt cctcgagcaa ctaagaagac
    16861 atctctgaag atcccaaaaa atcggaaaaa gtcctgatct tccaagaatg cagctgtact
    16921 tcttttgtaa acctccacag ctagaatatt ttcttcttcc aaataaggtg ttaaatcaaa
    16981 ttcagacgga gtgaacgaat cttcggcata cccgataaaa tgaccattca accaaataaa
    17041 cattgcttgt tctacaccag caaaatgaat cgagatttgt tttcccttta gaccttcttc
    17101 taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct ttagcagctg aaaagatccc
    17161 ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg cgaaatacat gtccctccca
    17221 cggatacatc gtattgatgt aatggatctt gtcataattt gctaattcaa tatgactagg
    17281 aacagtgatt tcatcaaaag aacaggcatc aaaatctttt ttataaaatg tttttggtcg
    17341 taccgaagga tttggcgaat aacaaaaacg ccatgatcca tttaaagact gtttaaggga
    17401 ggatgtggtt tctacttctt cccttgttgc ataacaaaca tgatcgctat gtgcatttga
    17461 ttggttcact ctaaaaactt gtggatcatc taaccatttt atatttgctt tcatactttt
    17521 ttccttctct ctcataactt tttgaaatga agcagttctg tttggaaatc accttgaaaa
    17581 tcggggaagt aaagtccaac tgtcatcaat tcggcccccg aaaatatccg cttcgaggtc
    17641 tgttcctgat aaagtgcctc atcatctaac cccatcagat atacttcatg gaacgctggt
    17701 tgagctgaag ctagtatcct ccctaaaaac acaatagctt catcttgttt aggagacaca
    17761 aacatccatg cggcaatatt ttcttcaaaa ggactcgcca aacgataata atggccatac
    17821 tggatcaccg gacgaatcgt ttgataggat ataatttggt cttttacttg ctttttttct
    17881 tcaggagaca gctttgtcaa atccagttca taaccaaaaa cagcgctcat agctgtttct
    17941 cctcttgttt tcaacgaagt agatctgtcg gtctgatgat ttggtacagc tgatacatga
    18001 gctgtgatgg acgaaatcgg ataagcaagg cttgttccat attggatttt catacgctcc
    18061 actgcatccg tgttatcact tgtccatgac tgcggcatat aataaataaa cccggcatca
    18121 aaccgtccac ctccaccaga acagccttcc cataagattt ccggataatc agttgtcaaa
    18181 tgttcaagta gttcataaag cccgagcata taacgatgcg ctacttctcc ttgtctctgt
    18241 gggtcaaggg taatcgaata gacatctgaa agcgaacggt tcatatccca tttgatgtag
    18301 tcaagaggaa tcgtatctaa aatctttctc atttgtttct caatcgtctg ccgaacatct
    18361 aaccttgtaa aatccagtac atgttgtgat ctggaagcag aaggcattct acctggctcc
    18421 tgcataagaa aatcaggatg tgttcgatac agttcagaat caaccgagat catttcaggt
    18481 tcaaaccata aaccaaattt caatcctttg ctatgagcat aatctgctat ttcacgtaat
    18541 ccatttgtca acttgccttc atactcgaac cagtctccta atgaagaatt gtccgcatct
    18601 ctttttccaa accagccatc atctaatacg aacatttcga tgcctagctc ctttgcttca
    18661 tcaatgatcg ccttgatttt ttcactattg aagtcaaagt aagtggcttc ccagttattg
    18721 accagaatcg gccgttcagc aaattgatga cgacctcttg cgattctttc acgtagcaac
    18781 tcatggtgga tctgactcat tttgttcaat ccctgacttg agtaagaaag gatcatttca
    18841 ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa aacgatggct gttgatccca
    18901 ccgacgactc tcaattgatt gatctgatct ttttcaagtt cgaaagaatg gttgccggaa
    18961 taaacaaatt gaagtccgat cgcttctcca gtattttctg tcgtatgatg atgaactaaa
    19021 gcaataaagt tattcatatg gtgactgctc gttcctcgac ggctttcaaa tacttttgtt
    19081 ccagataaaa cagattgccg tgaaatctgt ctttcattga catgtgctcc tggcaaagca
    19141 atgacttcat caaatcgcct agtatgggca aagtctagct ggaaactagc cgctttttct
    19201 agtttgattg tttctccggt ttcatttctt atctttacag atcgtgtgat cactgctcta
    19261 tcagtaaata tggtatagaa caaatcgaaa taaatcgctg tttctctatc cttaagtgaa
    19321 atcaccaacg tttgtgcctc tgacttgtcc atcacataag tttgaggcaa gccttcgatc
    19381 tctggcttcc catctgtaat ataatggctg tcatatctca gatccagtaa gtctgatcca
    19441 ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca tgctgccatg agaagagtat
    19501 tcttgcggta gtgtatcttt cgacagagac cggtcaggat ttaagggaac atttcctgaa
    19561 aatccacgat ctcttcgggg ataattttta ttgtctttgt actgcttgac tggtttgcca
    19621 aaataaatat gcgccaatac attgctttct tctatcttta tcagataaga aagaaatgta
    19681 tttcgtaaat ggaagactcg gctcttttca tcaaataaga tgaaattttt atctgttttt
    19741 ctatgcgtaa tatccatcat ttcactccca acaaaacgga aaccgtttac ttttttttat
    19801 aattcctgta tactgtttac taaacaattt tgtcaataaa aattttttat ttttttgagg
    19861 agtgtgtaaa aatggttgga attagagatg tcgcacgaaa ggcaaatgtc tctcctgcta
    19921 cagtttcccg tgtgttgaat aacgatcaga cgatccatgt ggctcagact actcggcaac
    19981 ggatagtaga ggcagctgct gcgttggatt atgacatcag tactcgtaaa tatatcaaaa
    20041 agagaatgcc ttcgattggt gtgatctcta cgatcggcaa agcgagcgaa gaacaggata
    20101 tctattacaa acatttgcga gtagggatgg aagaagaagc tcgacgtctg catttaggga
    20161 tgaatcgaat ctataatcta tctgataatc ctaaacaatg ggaagatcta gatcagttag
    20221 gtgcggtgat cgttgttggg actgttacga aagaatcgat taccgccttg ttaaaacaaa
    20281 acatgcaaat agtcgtcgtg gataaccctg acatccagca agaggtcgat atggtgtatg
    20341 cagatcttga acggatgact aaaaccgtac tggaattgtt cttagaaaat ggtcataaaa
    20401 gaatagccta tatcggggga tataaagtcg atatggatga attcggtggg aagcagattt
    20461 ctataaatga aaagaggatg cgtgcctatc agcattttat gatcgatcat cacttagaaa
    20521 aatatatgtc ttatcatcta ggtggctgga cagaaaaaca aggtgaggta cttgcgacta
    20581 atctattaga aaatgaatcc cctcttccta ctgccattct tgtcgggagc gatccaatgg
    20641 caattggtgt ctatcgggca ttgaaacaaa aaaatatcca aattggagaa gagattgttg
    20701 tagcaagctt tgataatatc gagacaatcg caaacctctc ccctggcttg accagtgttc
    20761 aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat ggcattggag cgaattgacg
    20821 gtatacggga cgaaccaatc attttgactt atcctgcacg attgattgtt agggaaagtt
    20881 ttatcccaag aacaaaaagg tattgaaaga gaggttgtga aaagccgctt cgtttcttca
    20941 tactcaaaac gaaacggctt tttcacaacc tcttacttat acttattcac aaaatccaat
    21001 gtctgctggt aacaattttg cgattctttt agcgtgtaat caaattggta ttcatgggta
    21061 atctcttttt ttgtatctgt ataaaacaag gattgcacgg gtacctttaa ttctgtcaac
    21121 cgattttcta atgcttgacc ttgctcctgg aatgagtatg catttccgtc agttatatac
    21181 gttggcggaa attccttaga aacatggtca gccacactag cttctttcaa ttgctcactc
    21241 gttttccaat cttttgttcc aatcaacgac cacgcaacgg ttttgacgaa aaacttcata
    21301 aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat caacaggtcc gcaataagaa
    21361 atggttcctt tcagactatc ttttggaagt agctgtttga ttttcatttg tttagcatac
    21421 gcatcattcg tttgtatagc tgcatattgc aatgcgattt gtgaacctgc actatctcca
    21481 ccaaaaaata attgttccat gtctagcaat ttgtcgtctt tttcttcagc taataaatct
    21541 ttgatcagtt cattcacttg aagaacttga ttagggtatt ctgaatcagg cgctaattca
    21601 taattcatcg caaccactgc gatgttggcg tctgaaacta attttgtcgc aaattctttg
    21661 acacccgatt tatctccgcc gacgaatcct ccaccatgta cccaaaatag aacaggaaca
    21721 ggccccttgc tgttttttgg atagtagatg tcataagtat tctctttata cttggactca
    21781 tacgtcaaat ctgttttttt cgccacgttt ttttctgctt gatcgaacgt ttttttatca
    21841 gtgatttgaa cagtatttga aaacatatgg ttgatcaaga atgctccagg tctgggggaa
    21901 agctggaagg caagaaagat tgcaaacgcg atcccaagaa tgattccgaa gaaccatccg
    21961 ataaatttaa gaattttctt tttcataagg ctccctcagt agttagtatt aagcattctg
    22021 attataccat agtgttattt cctatcaagc tctcctagat gatttaatga ttttccccaa
    22081 acttcttctg caatgctttt gacaaaagaa attttttcca ttgttcttca aacaaaacat
    22141 tttcttcttc tgttgaagca aatccacatt gaggacttaa gcacaaacga tccaaaggca
    22201 gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg gtgctcttcc atttcgccat
    22261 ttttcgttac agtcaaaatc taagacaact aatttatctt cagagacttt ctctaaaaga
    22321 acaaaactcc cagcacgttc actatcgtat tctaaataat aggcacggac attttcttga
    22381 gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg ccgccaaaat cgaataataa
    22441 tttccgcgtc aaacatgtat atttagtgtt gaatcatttg agaatatgaa aataaaaatc
    22501 tttttgatca atcagttaat caaattgaaa taacgaaaaa tctgagacag aatgacgttc
    22561 attctgaccc agatttgatt ttgcacaact caacagtcct tattggcaaa tcgccaaaat
    22621 aatgtagact aactaaaaag actaagaaac aataacaaaa gttaacactt cttagtcttt
    22681 ctttagcacg tctatttatt aaagatttta gggccttttc tcatgttttt acgatcattc
    22741 ttaggtgttt ccatttgttt ggatcggcct ccaccttgtt tctttttgat caattctttc
    22801 attttttctt tttggtccat ttttattctc ctttaacgaa tgaagcgact aattcgatat
    22861 gatgggtttg cgggaaaaga tctacaggct gaactttctt cacggcataa cctgcttctg
    22921 caaataactt agcatctctt gcaaaagttg ccggattaca tgagatatag acgattcgtt
    22981 ctggtgacat ttcgattgct gattcaataa aatgatgatc taatcctttt cgtggagggt
    23041 caactacgat cacagatggt ttgatccctt tttcttgcca ttttttcata actttttctg
    23101 cttttccgac ttcataatga acattttcga ttttattatt taaagcattg aactgtgcat
    23161 cttcaattgc ttctggaata acttccatcc catacacctt atccactctg tctgctaaag
    23221 acaagccaat cgtacctatt cctgaataag cgtcgatcac aatgtctttt ttatctaact
    23281 cggcaaactc gatggctgtt tggtacagat actctgcttg ttgagtattt acttgataaa
    23341 atgactttgc tgagattcga taggtttttc ctaatagctg atcttcgata tagtctctgc
    23401 catataaaac tttttctttg tctcctaaaa tcacatttgt tttttcttca ttgatatttt
    23461 ggatgaccga aaccacttct ggcaattctt catgaatagc ttcagcaatt tccttggatt
    23521 taaagaattt ttctttacga gtaactaaaa cgaccatcat ttcatgggaa taatgaccac
    23581 gacggataat gatgtgacga agctgtcctt catttttttc ttcattatat cctcgtactt
    23641 ggaaccgttg caagatatct ctgactactt tgattgcttg atcgatgaca ggatcttgga
    23701 tataaaaatc ttcgataggg actagatcat ggctattctt tttgtaaaaa ccggtggcta
    23761 actgtccatc gatacggcga acagggatct gtgctttatt acggtagccg aatggttctg
    23821 ccattccgac cgttggaagt acaggaactt ctggcatctt agcaatcttc gccattacat
    23881 gctctacttg tttttgtttg aagacaagct gttgttcata cttcaaatgg gctaaaggtg
    23941 cgatacctat gcgaagtaat gcattgtttt ctacaggctg acgatcaggt gattgtgtaa
    24001 taaatgtttc gacttttcca tatccaaact tattgcctgc ttttactact agtatttcta
    24061 cttcttctcc agggagtgca ttttcgataa ataatggata accatcgatt tttgctaccc
    24121 ccattccttc ataactcaag tcgacgattt cgactgtata tcgttcgttt ttctttacta
    24181 tttgctgttc tgtcatattt tgctccttta agcctatttt tcaatcctac tgaactctac
    24241 tataaatcag ctaattacac aactaaaacc ggcactgacc ttactacgtt cagcaccggc
    24301 ttttgattaa ttcttttgat taggtgtttc gtctgctatt tttccgtcac cgtcgatatc
    24361 ttcatccgtt aaacgttcga cttcttttac gaattctttg ctgacaacct ctaattcttc
    24421 ttcatctgta cctgtgattg cttcatcagg aatctgatcg gtattggcaa agaactcaat
    24481 gtgttgatga agattttgga aatgcatcgg tgcttccccg ccgtattcac catctaagtt
    24541 gatcattact ggtcgattga tatcatcttc tgtttcaacg aacaaactgc ttgttttggt
    24601 atagattatt cttggatcat cgacatgtcg accgccattc agcatgagtg ctgcaatatg
    24661 caagatctca aagatatttg ctgtcttcac aatgattaaa gaaaacttcc catcatccaa
    24721 tttggcatct ggcgcgatct gttcgaatcc tccaacagag ttcgtcagcc ctaggaaaaa
    24781 catcgaagca tttccgatat attccccttc atcatacttc aagcgcattt tgattggctt
    24841 tactcgaggg agcatctctg ctcctttcgc aagataagca agataaccaa aaatactctt
    24901 tagttctgat ggaacttcat aagtcaattc tgtcaaatag ccacctgcag cgatattgat
    24961 gaagtaactg ttatcagaaa ggccgatgtc catttttacg gtttggtgtt tttttatcac
    25021 ttctgctgct gctttaatat tatctctagg aatttttaat gctcgagcat agtcgttcgt
    25081 tgtaccagct gggatgatgg ccattttagg acggtgttca agcggagcga ttccattaac
    25141 cacttcgttg attgtgccat cgccaccagc tgccactact agatcaaaac ctagttctgc
    25201 gactctacat gcttcattct tggctgaatc tggttctggt gtagttgcat aggcgctggc
    25261 ttcaaatcct gcttcttcta atgcctgtag gatatccgcc aaattttttt tcaataattc
    25321 ttttcccgag gtggggttat aaattacgcg tgcttttttc attttcagcc tctatcgttt
    25381 cgctaattca tctttaagta gcttattcac gacaccagga tttgcttgtc ctttagttgc
    25441 tttcatgatt tgaccgacta ggaagccaac cgcacgatct tttccatttt tgaaatcatc
    25501 gacagattgt tggttgttat ccaaaatttc attaatgatt ggcagtagtt tgttcggatc
    25561 agataattgc acccaaccat ttttttcaac tacttcttgg gcttctccgc catttgtgat
    25621 caattcacgg aagacttttt tggcgatttt tgagctgatc gttccatcgg cgatcaaacg
    25681 aatcattcct gctaagttct caggtgtcaa ttttgtctca gctaattcca gtttctcact
    25741 gttcaagtaa gcagaaactt cacccatcaa ccagttagat gcttgcttgg catctgcacc
    25801 attttccaaa acagcttcaa aaaaatcaga catttctttt gtaagtgtca ataccattgc
    25861 gtcatactct ggaagtccaa actcacggat atagcgttcg cgacgagaag ctggcatctc
    25921 aggcaaacta gcttttactt tttgaatcca ttcgtcatcg atcacgaatt tcgggatatc
    25981 aggctctggg aagtaacgat aatcactaga cccttctttg acacgcatca aaactgtttt
    26041 attcgttgtt tcgtcaaaac ggcgtgtttc ttgttggatt tctcctcctg aaagaagaac
    26101 ttttgcttga cgtttttctt caaaagctaa accttttttc acgaaagata aagagttcaa
    26161 gtttttcaat tctgctttcg taccgaactc ttcttgtcca taagggcgaa gagaaatatt
    26221 ggcatcacag cgcatagagc cttcttccat tttcacatcg ctgacttctg taaattggat
    26281 aattgatcgc aatgcttcta gataagcgta tgcttcttct ggtgaacgca tatcagcttc
    26341 agaaacgatt tcgatcaaag gcgtgccttg tcggttcaaa tcaacgtaag aataaccgcc
    26401 aataccatgc atgttttttc cagcatcttc ttctaaatgg acacgttcga tccggatttt
    26461 tttcttttta ccttctactt cgatttcgat ccatccgtca tgaccgattg gttgatcaaa
    26521 ttgggaaatt tgatatgctt ttggattatc tgggtaaaag taatttttcc ggtcaaaatg
    26581 agtatcttta gagatttcac agtttaatgc caaagctgct ttcatcccga attccagcgc
    26641 agctttattc attactggca gcacgcctgg ataaccccag tcgatcacgt ttgtattgct
    26701 gtttggttct gcaccaaaat gagctggcgc tggagagaaa atttttgagt tggtttttaa
    26761 ctcgacgtgg acttctagtc caatgactgt ttcaaaattc attcgtcttt ccctcctaaa
    26821 atagctggtt gttgtttatg gaattctgtt gcttgttcaa acgcatatgc cgcttgatac
    26881 atcgtttttt catcaaaata attaccgatg atctgcaatc caactggtaa tccttctgat
    26941 aaacctgccg gtacagacat acctggaagt ccagccaagt tgacagggat cgttaagatg
    27001 tcactcatgt acattgtgat tggatcgtta atgttctcac cgattccgaa tgcaactgtt
    27061 ggtgaagatg gcccgatgat caagtcataa tctgcaaaga ctttttcaaa atctcgtttg
    27121 atcaatgtac ggacttgtcc tgcttttttg aagtaagcgt cataataacc cgcgcttaag
    27181 gagaatgtac ctaacatgat acggcgtttt acttcttcac cgaatccttc tgaacgtgag
    27241 ttgacatata catcatctaa tgatttcaca ttttcagagc gataaccgta gcggatacca
    27301 tcgaatcgtt gcaaattgga acttgcttct gatgaggcaa tgatataata aacagccaca
    27361 ccgtattttg aatgaggcaa gctgacttct tccacaacag cacctaatga acggaatgtt
    27421 tctgctgctt tcaatacagc ttcttttacg ccaggggcca caccttcgcc taagtattct
    27481 ttaggtaaag caatcttcat tcctttgatg tcgcctgtca gtccctctgc aaaatcagga
    27541 actgaaacgc ctgaagaagt accgtctttt tcgtcataac cgctgatagc tgtcaatgct
    27601 aatgcattat ctttcaccgt acgggtcatt ggtccgattt ggtcaagaga tgaagcaaag
    27661 gcaatcaaac caaaacgtga gacacggcca taagtaggtt tcatccctac gatgccgtta
    27721 aaagctgctg gttggcggat acttccccca gtatcactac ctaaagaaac tggaatttgt
    27781 ccagctgcaa ctgctgctgc agaaccacca gaagagccac caggtacttt tgttgggtcc
    27841 caagcatttt ttgttttctt gaaataagaa gtttctgtac ttccacccat agcaaattca
    27901 tccatgttta gcttaccaac agggatcata tctgcttgat agattttatc catgaccgtt
    27961 gcatcataaa ttggttcaaa attgtaaagg atcttagatg cagcggttgt caagatatct
    28021 tttgttacga tattatcctt gataccaatt ggaataccag caaggacgtt gctttcatca
    28081 atcccttttt catctaaagc ttttgcctgt tccaatgctt tttcttcgtt caatgtaatg
    28141 aatgcctcga cctcaggctc tgtttctttg attcgttcaa atgttgtttt tgtcaaatct
    28201 tgtacagtga tttctttcga tacaagcata tgatgcagtt cttctagaga acgattgtgt
    28261 aattctgtca ttatgcgcca gcctccccat tatcgatgat tgcgggtact ttgataaagc
    28321 cgtcttctgt ttccggcaca tttttcaata attcatcgcg gttccatcca gcttgcgccc
    28381 gatcttgtcg catcacgttt actgtttcaa ccacattcga cgtaaatgga acaccttccg
    28441 tatctacttc ttccagcatt tcaaccatat cgatgatttt acctaattgg tcggtaaaac
    28501 ttgcaagttc ttcatctgcg aacgcaagtt ttgctaattt ggcaacgtgt ttcacttgtt
    28561 cttcactaat cgccatacta ccccttcttt ctaaacgagt taaaaacttt gctctctatt
    28621 ttaacacaag agtgccgtgt ctgaaattgt ttattgaaat ttgtctgaaa aaactcattt
    28681 ttcattcttc tactgagcga cttttagcca atgcatctgc catttgatct tctgtccaaa
    28741 cttcgattcc taattcttgt gctttggtca gcttgctgcc agcatcttct cctgctacca
    28801 cgatatccgt ttttttcgat acgctaccag tcactttccc gccaagattt tcgatcgtct
    28861 cttttgcttc ttcacgagta aatcgtgtta gtttaccagt aaggactact gttttttctt
    28921 taaaaggaga ctcgacttct tgcaattggg catttcgaag ccctttgtat tcgaaattga
    28981 cgcctgcttg ttttaattca ttcatcaatt catggacttc ttcgttactg aaataagtga
    29041 ctacactgtc ggcaatgata tcaccgatcg tatcaagcgc aataatcgac tcatagtcac
    29101 ttttactcaa tgtttctaga tcaccgaaat gttctgctaa aatttttgct gctttcgctc
    29161 cgacatgtcg gattcctaac ccgaaaatca accgctcgac cgaattatct ttgctgttgt
    29221 cgattgctgt caaaatatta tttgctgatt tttcttttat tttgtccaac gtcaataact
    29281 cttcttctgt caatttgtaa agatcagcaa catctgctac tagtttttta tcatacatct
    29341 gttctagtac gcgcggcccc aacccatcga tattcatcgc atttcttgaa acaaagtggt
    29401 tcaaaccttc tttcatttga gcagggcatt taggattgat gcaccgtaag gctacttctt
    29461 catccaaatg gacaagttca cttccacaaa ctggacaatg tgtaggcaat tggtattctt
    29521 cgctgtcttt aggtcgttta tctaacacga cttgcgaaac ttctgggatg atgtctcccg
    29581 ctttataaat cagaactgta tctttcaagc ggatatcctt caacttaata taatcaccgt
    29641 tatgcaggct ggcacggctt actgtcgttc ctgctactcg gactggtgtc atgatagctg
    29701 ttggcgttac tacccctgtt cgaccgactg tccattcgat gttttcgatt agcgtttcaa
    29761 cttcttctgg cggaaacttg taagctgctg cccatctcgg tgctttgata gtaaaaccaa
    29821 gttgatcttg tagcgagaat tcattcactt tgatgacgat tccatcgatt tcatagggca
    29881 aatccacacg tttgtcatga tattcttcaa tgtatgacca cacttcatca atcgaatgac
    29941 atagacgttt ttcccgattc gtgtggaatc caattttttc tagctcttct agcgcatcat
    30001 actgggtttt tgcttgcata ggaccgaaat cagctactgt gtataaaaaa gtgtccagat
    30061 ttcttttcgc tgtgatttta gaatctaact gacgcaaaga accagctgcg gcgttccgag
    30121 gattcgcaaa gatatctttt ccctctgctt ctctgtcttg gttcaattgg acaaatgacc
    30181 gttttggcat gaaacattcg cctcttactt cgatgttcat tggttctttt aatttgattg
    30241 ggaccgaccg gacagttttt aggttttcag tgatgttttc tcctacagtt ccatccccgc
    30301 gagtcgcacc tctcacgaaa tttccatctt cataacgcaa agaaacggaa agtccatcta
    30361 tttttagttc acagcaatag tcaactacac gtcccactgc tttttgtaca cgttgatcaa
    30421 aagctatcag ctcttctttg ctgaaaacgt cgttcaaact gtaaagcgga atatcatgag
    30481 tgactttttc aaaaccttct aatacttttc cgcctactcg ttgagtggga gaatcagacg
    30541 tgatcaaatc aggatattgt tcctcgattg ctactaattc tgcgtattct ttatcataaa
    30601 catagtcttc cactgttggt ttatcttcta cgtagtattc gcgagaccat tggttcagtc
    30661 ttgtacgaag ttcttctgct cgtttagcag cttcgtcaat cgtcatttca tgttccatca
    30721 tttaccctcc actactaagc tttttcaatt ggcgcaaagg cagccaaaag acgttttact
    30781 ccttgacttg ggaaagccac atctagttct agatccttcg acgtcccgct tactcggacg
    30841 actgttccta gaccccattt tttgtgtttg actttatctc caggtttcca gctgttattt
    30901 tcccctccag tagcactttt agagggaaca accgctgtct ctggctgttt atagctatat
    30961 gctgtttttt tagcgaatac aggcgttttt ttaggcgtag gacgcatgcc ttcgatttcc
    31021 agtaactcct gatcgatttc ttctacaaaa cgagaaggtc ggttatattg cgtccgtcca
    31081 tataatgttc tggagaaagc atttgttaaa tacaacgctt cttctgctcg cgtgatcccc
    31141 acatatgcga gacggcgttc ttcctccagt tcgctttctt ccatcaatgc tcgagataaa
    31201 ggaaaaaccc cctcttctag accaatcagg aatacaactg gaaattctaa tcctttggct
    31261 gcatgcaaag tcatcaatgt cacttgggaa gcatcttctt ctaaattgtc aatgtcggaa
    31321 acaagtgcca gatcatttaa gaagaccgtt agtttttctt ctggtgcatc agcgtcttct
    31381 tcattttgct gttcgaattg tttgtcgaat tcttgtgtga ccgttaaaaa ttcctccaag
    31441 ttttcgatgc gtgcttgtgc ttctaatgta ttttggattt ttaagtcttc tagatatccg
    31501 ctacgatcca aaacctcttt cgtcaattct gtcactgtca agtatgggat catctgagtg
    31561 acttcttgga tcatctctcc aaatgcacct aattgctgtc ctgcttttcc accgatattt
    31621 gccagatcca cattttgcgc tgcttcaagc agtggccatt catgaagaga agcaaaactg
    31681 cgtagttttt cgatagatcc tggtccgatg cctcgtttgg gcgaattaac gatacgctca
    31741 aaactgattg aatcttgagg atttaccagc acattcaaat acgctaaaat atctttgatt
    31801 tctttacgat cgtagaactt gtgccctcca accattttat aaggaatatt tgctttcaac
    31861 agagtttctt ccattacacg agattgtgcg ttcgtccggt acaagatggc aaagtcgccg
    31921 taattccgat gattgcttcg aatctcttct tgcatccggt ctacgataaa acgggtttcg
    31981 tctcgttcat tatctgcacg gtagtaagtg atcttgtttc cttctttgtt ttctgtccac
    32041 aagttttttg gttttcgatt gctattgttt tcaatgactt ggtttgctgc gctaaggatg
    32101 tttttcgtgg agcgatagtt ttgttctagc aaaattactg cagcatctgg ataatctttt
    32161 tcaaaatcca agatgttctg catatctgca ccgcgccagc cgtaaatact ttgatctgca
    32221 tctcccacga cgcacaggtt cctaaatcta cctgccaata aattgactag cgtatactgt
    32281 gcgtgatttg tatcttggta ctcatctaca tgaatataat ggaatttgtt ttgataatac
    32341 gtgagtgaat caggatgttc ttcaaataat cgaatcgtat tcatgatcag gtcgtcaaag
    32401 tccatacatt gattatattg aagctctttt tggtaagcag cataacattt tgccgcaatc
    32461 tcttcgtaat aactgccttg catttttgca aaatcctgag gggtctgcag gctgtttttt
    32521 gcttgagaga ttgttcctaa tatacttcga ggatcatatt ttttcggatc aatgttcagt
    32581 tcttttagta tccgtttcat caaggtcagc tgttcagaag aatcgatgat tgtaaagttc
    32641 cggttatacc cgataaaatc aacatctctt cttaaaatac gcacacacat cgagtgaaaa
    32701 gtcgataccc agacatcttc gcctccagat gcgagaatcg cattgacacg ttctttcatt
    32761 tcttttgcag ccttattggt aaaagtaatc gctaggatgt tccaaggatt gacttctttt
    32821 tcctcaatca aataggcaat gcggtgtgtc agcactctcg tctttccact tcctgcacct
    32881 gccattagca gtaatggtcc gtcagtgtga agaacagctt ctttctgacg ggggttcatc
    32941 ccgtttaata attcagcttt ggatgacatt aacaacatcc tttcttttat caatcttgtt
    33001 aattatagca ttttcttggc tttcattaaa ctagctagtt caaaatcatt tgtttctttt
    33061 tatggatttt tccttgtcaa ttcgttgatt tcgcgctaaa ttaaaagaaa gcgaggcgtt
    33121 tgaatggaaa aaaaaggaaa aatcaagaaa ttagataaga ctcagatata ttttattcta
    33181 aaaggaatat ttgttggact gctgacagga atcgtcgtta gcctgtttcg attatctatc
    33241 gaaaagctaa gcgatttagt tcgaagtatc tatgaaatga gtcgggaaca gccgatttac
    33301 ttaattggcc tagctatttg ctgcatcctt gcagcatttt tcgtgggtta tctggtcaaa
    33361 aatgaaccgg atatcaaggg aagcgggatt ccacaagtag agggacagct tcgcggggaa
    33421 ttatcaatga actggttctc tgttttatgg aaaaagttca ttggcggtgt actttcagtt
    33481 ggtgcgggcc tttttctagg tagagaagga ccttctatac agcttggcgc atccattgga
    33541 caaggagctg gacaattgtt tcggagtcca tcttcagaag aaaagatttt aatttctagc
    33601 ggtgcaagta gcggacttgc agcagcattc aatgctccta tcgcaggatt actctttgtt
    33661 ttagaagaaa tccatcactc cttttctcca cttgtttggc tgacatcatt tgcttcagca
    33721 atcactgcta acttcgtctc tctttacttt ttcggcttga gacctgtttt atatctaggt
    33781 gaccttcctt ctttgccgtt gaaatattat ggttccttag tgatcttagg agtacttcta
    33841 ggcatcttag gttttattta tcagaatgtc ttgctggctt tgccaaaatt ttacaaccga
    33901 ttgcctttac cagcttattt tcacgggttc gttcctttct tgctgatttt gccaattggt
    33961 tatttatggc ctagtactct aggcggaggc aatcaaatcg ttttagcttt tggacatgct
    34021 tccttgccaa tcattatgat tatcggtttg tttgttcttc gattcgtttt ttccatgatt
    34081 tcttacggtg ggggtcttcc aggggggatt ttccttccga tattgacatt gggggcttta
    34141 atcggtagct tttatggaaa cattatggtt gatttcggga tggatccaat ctacatcaag
    34201 gattttgtcg ttattgccat ggctggttat ttcacagcga ttggaaaagc accgctgaca
    34261 gcaattattt tagtgacaga aatggttggc tctcttaatc atctgatgcc tttaggattg
    34321 gctgctcttg ttgcttatat cgtcaatgac cttctcggcg gtaatccaat ttacgaatca
    34381 ttattggaac gtctacttgg aaatactcag accgcctcac taaaaggtgc aaggacaact
    34441 tttgattttc cagtaacggc agagagttct ttagacggat taatggtacg agacttcaat
    34501 tggcctaaaa atatgctgct aatctctata cgcagaggaa atcaggaaat cttgactcac
    34561 ggtgatacga tcatgaatgt aggagatatt ttggttatct tgactgatga agcaaacttg
    34621 ccaagaatca agcaggaaat cgaggctaaa tcttctatca caaatttgaa gcaatcattt
    34681 taacgaacat ggaaaaacta ttttacaaca actattcatc tacactactt gattctatat
    34741 gattctataa aaaaagaaga ggctgggaaa a
//
LOCUS       DADVXE010000023        34673 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.023, whole genome shotgun sequence.
ACCESSION   DADVXE010000023 DADVXE010000000
VERSION     DADVXE010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34673
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.023"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="KB913_001236"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="KB913_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBB6819609.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="KB913_001237"
     CDS             complement(2020..2922)
                     /locus_tag="KB913_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6819610.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3611)
                     /locus_tag="KB913_001238"
     CDS             complement(2919..3611)
                     /locus_tag="KB913_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBB6819611.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="KB913_001239"
     CDS             complement(3654..4295)
                     /locus_tag="KB913_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6819612.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="KB913_001240"
     CDS             complement(4333..4647)
                     /locus_tag="KB913_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819613.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5987)
                     /locus_tag="KB913_001241"
                     /pseudo
     CDS             complement(4635..5987)
                     /locus_tag="KB913_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5984..6916)
                     /locus_tag="KB913_001242"
     CDS             complement(5984..6916)
                     /locus_tag="KB913_001242"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBB6819614.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="KB913_001243"
     CDS             complement(6913..7689)
                     /locus_tag="KB913_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBB6819615.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="KB913_001244"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="KB913_001244"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBB6819616.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="KB913_001245"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="KB913_001245"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBB6819617.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="KB913_001246"
     CDS             complement(12014..13294)
                     /locus_tag="KB913_001246"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBB6819618.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="KB913_001247"
     CDS             complement(13313..14239)
                     /locus_tag="KB913_001247"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBB6819619.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="KB913_001248"
     CDS             complement(14252..15535)
                     /locus_tag="KB913_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBB6819620.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="KB913_001249"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="KB913_001249"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBB6819621.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="KB913_001250"
     CDS             complement(16323..17234)
                     /locus_tag="KB913_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6819622.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="KB913_001251"
     CDS             complement(17231..17695)
                     /locus_tag="KB913_001251"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBB6819623.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="KB913_001252"
     CDS             complement(17700..18398)
                     /locus_tag="KB913_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6819624.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="KB913_001253"
     CDS             complement(18385..18771)
                     /locus_tag="KB913_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819625.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="KB913_001254"
     CDS             complement(18918..20588)
                     /locus_tag="KB913_001254"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBB6819626.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="KB913_001255"
     CDS             20771..21004
                     /locus_tag="KB913_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBB6819627.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="KB913_001256"
     CDS             complement(21103..21534)
                     /locus_tag="KB913_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBB6819628.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="KB913_001257"
     CDS             21613..22026
                     /locus_tag="KB913_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBB6819629.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="KB913_001258"
     CDS             complement(22064..23212)
                     /locus_tag="KB913_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6819630.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="KB913_001259"
     CDS             complement(23334..23930)
                     /locus_tag="KB913_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6819631.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="KB913_001260"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="KB913_001260"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBB6819632.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="KB913_001261"
     CDS             27160..27591
                     /locus_tag="KB913_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6819633.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="KB913_001262"
     CDS             complement(27636..28985)
                     /locus_tag="KB913_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6819634.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="KB913_001263"
     CDS             complement(29055..30218)
                     /locus_tag="KB913_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBB6819635.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="KB913_001264"
     CDS             30347..30670
                     /locus_tag="KB913_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819636.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="KB913_001265"
     CDS             complement(30853..32202)
                     /locus_tag="KB913_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6819637.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="KB913_001266"
     CDS             complement(32271..33224)
                     /locus_tag="KB913_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBB6819638.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="KB913_001267"
     CDS             complement(33326..34516)
                     /locus_tag="KB913_001267"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBB6819639.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9850 a         7595 c         6088 g        11140 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaac ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg
    34621 attatgagaa ttatttaacc acatttttta tttacagtat ctttttactt tca
//
LOCUS       DADVXE010000024        34520 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.024, whole genome shotgun sequence.
ACCESSION   DADVXE010000024 DADVXE010000000
VERSION     DADVXE010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.024"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            212..604
                     /locus_tag="KB913_001268"
     CDS             212..604
                     /locus_tag="KB913_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6819640.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="KB913_001269"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="KB913_001269"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBB6819641.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="KB913_001270"
     CDS             3165..4775
                     /locus_tag="KB913_001270"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBB6819642.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="KB913_001271"
     CDS             5067..5936
                     /locus_tag="KB913_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBB6819643.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="KB913_001272"
     CDS             6101..7372
                     /locus_tag="KB913_001272"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBB6819644.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="KB913_001273"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="KB913_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBB6819645.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="KB913_001274"
     CDS             8763..9026
                     /locus_tag="KB913_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBB6819646.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="KB913_001275"
     CDS             9471..9920
                     /locus_tag="KB913_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6819647.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="KB913_001276"
     CDS             9977..11395
                     /locus_tag="KB913_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6819648.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="KB913_001277"
     CDS             11395..12255
                     /locus_tag="KB913_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBB6819649.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="KB913_001278"
     CDS             12429..13202
                     /locus_tag="KB913_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6819650.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="KB913_001279"
     CDS             13349..13714
                     /locus_tag="KB913_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBB6819651.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="KB913_001280"
     CDS             complement(13862..15070)
                     /locus_tag="KB913_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6819652.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="KB913_001281"
     CDS             complement(15089..15367)
                     /locus_tag="KB913_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819653.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="KB913_001282"
     CDS             15521..16216
                     /locus_tag="KB913_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6819654.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="KB913_001283"
     CDS             complement(16658..17455)
                     /locus_tag="KB913_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBB6819655.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="KB913_001284"
     CDS             complement(17452..18636)
                     /locus_tag="KB913_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBB6819656.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="KB913_001285"
     CDS             complement(18661..19908)
                     /locus_tag="KB913_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBB6819657.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="KB913_001286"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="KB913_001286"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBB6819658.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="KB913_001287"
     CDS             21888..22202
                     /locus_tag="KB913_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBB6819659.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="KB913_001288"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="KB913_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBB6819660.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="KB913_001289"
     CDS             22887..23531
                     /locus_tag="KB913_001289"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBB6819661.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="KB913_001290"
     CDS             23546..23875
                     /locus_tag="KB913_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBB6819662.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="KB913_001291"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="KB913_001291"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBB6819663.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="KB913_001292"
     CDS             24863..25687
                     /locus_tag="KB913_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBB6819664.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="KB913_001293"
     CDS             25680..26027
                     /locus_tag="KB913_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBB6819665.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="KB913_001294"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="KB913_001294"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBB6819666.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="KB913_001295"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="KB913_001295"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBB6819667.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="KB913_001296"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="KB913_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBB6819668.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="KB913_001297"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="KB913_001297"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBB6819669.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="KB913_001298"
     CDS             31657..32451
                     /locus_tag="KB913_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6819670.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="KB913_001299"
     CDS             32441..34483
                     /locus_tag="KB913_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6819671.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
BASE COUNT        11101 a         6121 c         7249 g        10049 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat
//
LOCUS       DADVXE010000025        34422 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.025, whole genome shotgun sequence.
ACCESSION   DADVXE010000025 DADVXE010000000
VERSION     DADVXE010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.025"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            352..1041
                     /locus_tag="KB913_001300"
     CDS             352..1041
                     /locus_tag="KB913_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6819672.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1028..2236
                     /locus_tag="KB913_001301"
     CDS             1028..2236
                     /locus_tag="KB913_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6819673.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2530..3801
                     /gene="serS"
                     /locus_tag="KB913_001302"
     CDS             2530..3801
                     /gene="serS"
                     /locus_tag="KB913_001302"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBB6819674.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="KB913_001303"
     CDS             complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="KB913_001303"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBB6819675.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6339..7034)
                     /locus_tag="KB913_001304"
     CDS             complement(6339..7034)
                     /locus_tag="KB913_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBB6819676.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="KB913_001305"
     CDS             complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="KB913_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBB6819677.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8233..8424)
                     /locus_tag="KB913_001306"
     CDS             complement(8233..8424)
                     /locus_tag="KB913_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBB6819678.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8445..9335)
                     /locus_tag="KB913_001307"
     CDS             complement(8445..9335)
                     /locus_tag="KB913_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBB6819679.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9322..10089)
                     /locus_tag="KB913_001308"
     CDS             complement(9322..10089)
                     /locus_tag="KB913_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6819680.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="KB913_001309"
     CDS             complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="KB913_001309"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBB6819681.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="KB913_001310"
     CDS             complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="KB913_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBB6819682.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="KB913_001311"
     CDS             complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="KB913_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBB6819683.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14660..15043
                     /locus_tag="KB913_001312"
     CDS             14660..15043
                     /locus_tag="KB913_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819684.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15211..15969)
                     /locus_tag="KB913_001313"
     CDS             complement(15211..15969)
                     /locus_tag="KB913_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBB6819685.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(15987..16805)
                     /locus_tag="KB913_001314"
     CDS             complement(15987..16805)
                     /locus_tag="KB913_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBB6819686.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="KB913_001315"
     CDS             complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="KB913_001315"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBB6819687.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="KB913_001316"
     CDS             complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="KB913_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBB6819688.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            17933..19267
                     /gene="dnaA"
                     /locus_tag="KB913_001317"
     CDS             17933..19267
                     /gene="dnaA"
                     /locus_tag="KB913_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBB6819689.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19465..20595
                     /gene="dnaN"
                     /locus_tag="KB913_001318"
     CDS             19465..20595
                     /gene="dnaN"
                     /locus_tag="KB913_001318"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBB6819690.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            20824..21066
                     /gene="yaaA"
                     /locus_tag="KB913_001319"
     CDS             20824..21066
                     /gene="yaaA"
                     /locus_tag="KB913_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBB6819691.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21053..22177
                     /gene="recF"
                     /locus_tag="KB913_001320"
     CDS             21053..22177
                     /gene="recF"
                     /locus_tag="KB913_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBB6819692.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22174..24120
                     /gene="gyrB"
                     /locus_tag="KB913_001321"
     CDS             22174..24120
                     /gene="gyrB"
                     /locus_tag="KB913_001321"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBB6819693.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24140..26611
                     /gene="gyrA"
                     /locus_tag="KB913_001322"
     CDS             24140..26611
                     /gene="gyrA"
                     /locus_tag="KB913_001322"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBB6819694.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            26847..27146
                     /locus_tag="KB913_001323"
     CDS             26847..27146
                     /locus_tag="KB913_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBB6819695.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27196..27708
                     /gene="ssb"
                     /locus_tag="KB913_001324"
     CDS             27196..27708
                     /gene="ssb"
                     /locus_tag="KB913_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBB6819696.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27734..27970
                     /locus_tag="KB913_001325"
     CDS             27734..27970
                     /locus_tag="KB913_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBB6819697.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28113..30086
                     /locus_tag="KB913_001326"
     CDS             28113..30086
                     /locus_tag="KB913_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBB6819698.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30092..30544
                     /gene="rplI"
                     /locus_tag="KB913_001327"
     CDS             30092..30544
                     /gene="rplI"
                     /locus_tag="KB913_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBB6819699.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            30818..32185
                     /gene="dnaB"
                     /locus_tag="KB913_001328"
     CDS             30818..32185
                     /gene="dnaB"
                     /locus_tag="KB913_001328"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBB6819700.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            32965..34257
                     /locus_tag="KB913_001329"
     CDS             32965..34257
                     /locus_tag="KB913_001329"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBB6819701.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10505 a         6693 c         6817 g        10407 t
ORIGIN      
        1 tttccaacat gtcaacaact tattttttat tatttaataa gttattggtg ttcttttgaa
       61 caaataataa tatatcaaca tcacatgtga aagtcaataa gaaaatgctt atttatcaac
      121 atttctagct tacatgatca ttggttagtt ctggtccttt ttcgttcgtc tttataactc
      181 cgagagacgt aaaatccttt tgttttcagt ttaatgttca tgttcttgtc ttattcacac
      241 caactagatg tctcaccttc taaaattttc cttaacaaag tgctgctttt atctatttct
      301 gctttttttt gctagaataa tagtaacaat atgactctgg aggatttatt tatgaaaatt
      361 ttgattgctg acgatgataa agaaatcgtt gaattattaa gtatctatgt tcacaatgag
      421 gggtatgaag cagtaaaggc ttatgatggg aaagaagcat tatctaaaat cagaacaatc
      481 cctgatattg aattacttat tttagatatc atgatgcctg agatggatgg gatgcaagta
      541 gtgaaagagc tacgaaaaga atcccaaata ccaatcatta tgctgacagc aaaaactact
      601 gatatggata agatcaaagg actggtcgct ggtgcagatg attatgtgac caagccattt
      661 aatccgttag aagtaatggc tagagtaaag tctttattac ggcgtacaaa aatgcagatt
      721 gccccagatc agcctgatgt attagaagta aatgcattaa tcatcaataa agactctcat
      781 gaagttaaaa caatcgatgg gaaagaaatc cagttaacag ctttggaatt cggtatcctc
      841 tacttgcttg ctagtcatcc taatcgagta tttagcgcgg atgaaatttt tgagcgtgtt
      901 tggaaacaag aaagtattgt ctctgctaaa actgtcatgg ttcacgttag tcatttaaga
      961 gataagattg aagaagcaac tggtggtgaa aaagtcattc aaaccgtttg gggagtgggc
     1021 tataaaattg acgcaagata gtaaacgagc aactgaaaaa cgccgtcgga tcaatttgac
     1081 ttcaaaagaa atcagcgaat tgttagcgga aggaatcatc acgattatcc ttttgcttct
     1141 attaaatgtt tctattctgg ttgttatcag ttcggtgatc aacagttcac cttctttgac
     1201 gaatgcgatt tgggattcaa agaatatttt tgcagaacga ttgaacactg atttgttctg
     1261 gaacggccgg aattttatta ttcccttttt ctttctatta gatattggtg ttttgtattg
     1321 gcgcttgatt cgaagatatc gccaaatgca attgcggcat atcatcagcg aacttcacta
     1381 catcgcaaac ggaaattatg atcatcgtat cccttttgaa ctgagtggtg acttaagccg
     1441 agtggtaaca agtatcaatg gattggtgga tagtaccgta gcagcgattg aagacgaacg
     1501 taaaatcgaa aaatcaaaag atgaattgat cacgaatgtc agtcatgata tccgtacccc
     1561 actcacgtcc atcattggat acctaggact gatagaagat ggccagtatc actcagaaga
     1621 agatctttta aagtatacgc atactgctta tatcaaagca aagcagatga aatctttagt
     1681 ggacgactta tttgaataca ctaaggtacg ccagcctgct gtcccggtga atttttctgc
     1741 ctttgacatg atccagttga tcgaacagtt agcagctgat tttgagttgg aagcttctaa
     1801 aaaaaatatc caaatacttg ttcaatcaaa agtagactcc cttatcatgg atggcgatac
     1861 cgaaaaactt gtacgtgtct tcaataatct tttgacgaat gcgttgaaat acggaaaagg
     1921 agcaacgaag atcgtaatcg aagtagaacg tatcggttca gaagttgttg caacagtcaa
     1981 aaataacgga gcaatgatcc cacaacaggc aatcgataat ctattcgacc gtttttatcg
     2041 tgtagaagaa tctcgttcac aagcaactgg aggaactgga cttggtttag caatcgctca
     2101 aagcattgtg gctttgcacg gcggatacat ttatgcaaaa tcagataagc aatggacttc
     2161 tttcatcatg caccttccaa tcaagaaaaa tgaaaaatta cctattgata cacaggaagt
     2221 tattgacgaa agctgaaata ttcgctattc ttattacaat tattagaata aatgaaaaac
     2281 acagaaccca gtacacttta ttctttttca gagagctgat ggcaggtgta aatcagcaaa
     2341 ggataatttg gaagttccag ttcgtttacg tgccctttcg aaataagaaa ggtcggttca
     2401 acagccgtta tgtgttcaac aagtgcagct gacgctgaac ttgggtggta ccgcgaattt
     2461 cagactgatt cgtcccaaga ataatgggat ggatcagtct ttttttattt tcaaaaagga
     2521 ggaaatcata tgttagatgt aaaaatgatg cgacaaaata ttgaagaagt acaagaaaaa
     2581 ttgatgactc ggggcgtaaa aaaagaaaca ttagctgaat tcatggaact agatgaaaat
     2641 cgtcgtaagc tactagtcaa aagtgaagaa ttaaaaaaat atcgaaatga tgtttctgct
     2701 gagatcgccc aattgaagcg tgcaaaagaa gatgcttctg ctaaaatcgc tgaaatgaaa
     2761 gaagtcggtg gcaacatcaa agcattggat actgaaattg ctgaagtgga tgaaaaattg
     2821 aaacaaattg caactacttt gccaaacctt ccccatgatt ctgtgccagt tggaacagat
     2881 gaagaggaca atgtagaaat ccgtcgttgg agcgaaccac gtacatttgc ttttgaacca
     2941 aaaccacact gggaaattgc agaaaatctt gatattttag attttgaacg tggcgcaaaa
     3001 gtagccggta gccgttttgt ctattacaaa ggattaggtg ctcgattaga acgtgctgtc
     3061 tacaacttca tgcttgatca gcatatttac gaacacggct atactgaaat gatcactcct
     3121 tatatcgtca acagtaaagc gatgtttggt acgggacaat ttccaaaatt caaagaagat
     3181 gttttccaat tggagaatac tgatctaaca ttaatcccaa cagctgaagt accattaact
     3241 aactattata atgatgaaat tttagatggt gcagatttac ctatttattt cactgcacta
     3301 agccctgctt ttcgttctga agccggaagt gctggtcggg atacacgagg actgattcgt
     3361 cttcaccaat tcaataaagt agaaatggtc aaattttcgg atgtagagca ttcttacgaa
     3421 gaattggaaa aaatgacagc tgatgcagaa gatatcttga aaaaattgca tttgccttat
     3481 cgtgtgatgg ccttatcaac tggagacatg ggcttttctg cagctaaaac ttatgactta
     3541 gaagtatgga tacctgcaca agatacttat cgtgaaatca gttcttgttc taactgtgaa
     3601 gatttccaag cacgccgcgc aatgatccgt tatcgcgata atgatggaaa aatccactat
     3661 actcatactc tgaatggttc aggacttgca gttggccgta cagtagctgc cattttggaa
     3721 aactaccaaa atgaagatgg ttctgtcaca gttccagaag cgctcgttcc ttatatgggg
     3781 aatctgaaag ttattaaata aagaggctgt gaaaaagccg cttagtttcg agtattaaga
     3841 aaaattttgt gaaaatggct ttccacattt ttgcataaat tggacttaat accgagaaac
     3901 tggcttttga acaccattta tcgagaggtt gtgaaatcag cgaattaacc tgagtattag
     3961 agaaaaaaat ggaaaaatag tccctcatat tttaccgttt gttgaactaa taccgagggt
     4021 cagctgattg aacaccgttt agtggagagg tcgtaagcct accccccagc tcctagttac
     4081 aaggacaaat tcaaaaaaca gctcttcata ttttatgaat gttgtacttg tgattcggag
     4141 gtggcaaggg aacactgttt attcaaaaag aggctgggac agaagcgttt aactccaaga
     4201 aataagaaga aattcacgaa aattgctttt caaatttttg tgaatttctt cttatttccg
     4261 aaggagttgc ttctacttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct
     4321 ttacttttgt cccacgctct ttaatgtttt taagattcaa ctgaatagtt tggtgcttct
     4381 tttgtgattt gtacatcatg agggtgtgat tcttttaatc cactgccgct catttggata
     4441 aattgcgctt catcacgtaa ttgctgtaga ttggctgccc caacataacc cattcctgaa
     4501 cgcaaaccgc cgatcatttg gaaaataata tctgcaacac ttcctttata agcaacccga
     4561 ccttcgattc cttctggtac taatttattt gcttcattga cactaccttg gaagtaacgg
     4621 tcttttgaac ctttttccat cgcgcctaat gagcccatac ctcggtatgt tttgaatcga
     4681 cgtccttgga agatttcgaa ttcacctggt gattcatctg tccctgccaa catacttcct
     4741 agcatcactg catgtccgcc ggcagctaat gctttgacga tgtcaccaga atatttgatc
     4801 cctccgtctg caataatcgc tttgccatat tgacgagcaa ctgatgctgc atcataaata
     4861 gctgtgagct gaggtacacc tacaccggct accacacgtg tcgtacaaat cgatcctggt
     4921 ccgataccaa cttttacgac atctacacct gcatcatata aagcttttgt cgcttcagcc
     4981 gtcgcaacgt ttcctgcaat caatgttgca tctgcaaaag ttgaacggat ttcttgaatt
     5041 tttcggatca cacctgcact atgtccatga gctgtatcga tgatgattgc atctgcccct
     5101 gcttctaata aagcattcgc acgctcaaat gtatcgcttg ttacaccaac ggctgctgct
     5161 acaagcaatc gaccatgttc atcttttgct gcatttggaa attcgatcac tttctcgatg
     5221 tctttgatcg tgatcaatcc gcttaaacga ccttcgttat ctacgattgg taatttttcg
     5281 attttatgtt tttgcaaaat cttttctgca tcttttagag aggtacctac tggggcagtc
     5341 actaagttgt cttttgtcat cacatcagca atcggcatgt gataatctgt tacaaaacgc
     5401 atgtcgcggt ttgtaattat ccctaccaat tttctgtttt caagtgtttc aacgattggc
     5461 acaccactga tacgatattt gctcatcaat tcttctgcgt ctgctacaag atgctgtggc
     5521 gttaagaaga acggatcaat gattacgcca ctttcagaac gtttgacttt tcttacttca
     5581 tccgcttgct ggctgatcgt catgttttta tggatcacac ctagtccgcc ttgtcttgcc
     5641 atagcaatgg ccatcttgct gtcggtaaca gtatccatac ttgcactgat gattggaata
     5701 ttcaacttaa tatttttagc taattgtacg ctcatatcca cttcgtttgg taacacgtga
     5761 ctttctgctg gtatcaataa gacatcatca aaagtaaatc cttttttcgt gaactttgtt
     5821 tcccagttgg acatttttag taccactcct ctaatttagt ttatctatta aaataattga
     5881 ttttttcatt taagtcaatg atctacttgg aatcaagtta gctttctcat agaataccaa
     5941 tataaagcgt ttacatctgt gtgtattaaa agagattgta aaaaagctgt cctgcatcaa
     6001 gtaataagaa cagccaatca aaaacagctt ctcatgtttt tgaattggtt gggtttatta
     6061 ccgcagatgc aaacttttga acaccgttta gtggagaggc tgtgaaaaag ctgcttagtt
     6121 tcgagtagta agaaaaattt tgtgaaaatg gctttccaca tttttgcata aattggactt
     6181 aataccgaga aactggcttt tgaacaccgt ttatcgtaaa aagggactgt gacaagactt
     6241 ttgtcacagt cccttactat tatttaacta tggataaaca aaatgaggtt ctttactacc
     6301 cctagatatc tagcaaaata gctgatcttt ttgctagttt atcttcttgg gacggataaa
     6361 cttccaataa tcccgtattt tttcttcaag tagtaacgga ttgctaaagc agttgccccg
     6421 ataatgataa ctactactgg atctaatact ggattgataa ctggtggcaa tagtgttgtc
     6481 gcagaaaaca gtacgaccca aagaagtgtc gttccaccta ggataagcaa tgtcttaccc
     6541 attcctggtt tcttgcttcg atctgctccg ggatattcat attgatagat gtatttgtac
     6601 atcatataaa agacccagcc accgattgca gaacctagaa cgagtgtaga aaagccataa
     6661 gctggcgttg ttccacgtga aaacaatccg gtaatcgcaa tcatgatact taatagacca
     6721 agcaacagca acgtattatc taaccacatc aataaagggg tggatgaatt ttttacttct
     6781 gctggcttat tgatgattgc ttccgttctt tcagagactg tcccaaacaa ttgacgggct
     6841 gttcttccgc ctttttgttc tgcaactaaa gtaggcagaa tgtcatgaag ggcttttact
     6901 ttttcttctt cagacaaatt cgctgcttct aaagattttt tcaaatcaaa aatgtactgt
     6961 tgatttcttt tggttaattt tgtttctaaa ctattgtttt cttttacgat tgctcgtaat
     7021 tgttctggtt ccattatcta atagtcctcc ttagccgttc cttttctcaa cggtcgtcac
     7081 aaaagacatt ctaccatatt ctacagctag tttgatagcc cttttacaca ttaaagcgga
     7141 ataacattac gtcgccgtct tgtacgacat aatcttttcc ttctaatcga acacgtccag
     7201 cttcttttgc tgcatgcatg tttccgtaat gatccaagtc ttcaaaagag acagtttctg
     7261 cacggataaa tccgcgttcg aaatctgaat ggatgattcc tgctgcttgt ggtgctttga
     7321 ttcctttttt gaatgtccaa gcacgtactt cttgttcccc agcagtaaag taagtagcta
     7381 agcctaacaa atcataagca gcacggatca actgatccaa acctgattct tcgattccta
     7441 aagcttctaa aaattccgct ttgtcttctt catctaattc tgcgatttct tcttctgcac
     7501 gagcactgac cacgatcact tctgcatttt cttctgcagc aaagttgcgc acttcttgta
     7561 cataatgatt cgcgtctgca tctgctacgt catcttctga gacattggct acataaagaa
     7621 ttggttttgt cgtcaataaa aatagtgatt taacgatttt ttgttcttct tcagtaaatt
     7681 cgatcgttcg ggcagatttt ccttcttcca gtacaggttt gattttatcc agtacagcta
     7741 gttctgccac tgcatcttta tctttggttt tagcaacttt tgctacacga gtatagcgtt
     7801 tgttgataga ttctaagtct gctaacacta gttccaagtt gatcgtatca atatcttcta
     7861 gtggatcaac acgtccttct acgtgagtaa tattatcatc atcaaaacag cgaacaacgt
     7921 gacaaatagc gtctacttgg cggatatggc ttaagaattg atttcccaaa ccttctcctt
     7981 tacttgcgcc ttttacgatt ccagcaatat ctgtaaattc aaaagtcgtc ggaacagttt
     8041 ttttcggatg tacaagttct gttaagcgtt gcaaacgcca gtcaggtact tctaccatcc
     8101 ctacgttggg gtcgatcgtc gcaaagggat agtttgctgc ttctgctcct gcttttgtga
     8161 tcgcattaaa caaagttgat tttcctacgt tgggcaaccc aacaattcca gcagtcaatg
     8221 ccataaattt attcactctt tctctgcatt tttttcaatt acttttttta atttcttttc
     8281 aaaatctcga cgggtcatca tgacgatatg tccgcaattc atacatctga ttttgatatc
     8341 tgcgcccatt cgaatgactt cccagcgatt cgtctggcaa gcgtgaggtt ttttcatttc
     8401 aacgatatcg tgcaagtcgt acataaaaat agcctccttt ttgtttattc ttcatcaaat
     8461 tgaatattca agatatcaag aattcgagtc aaatcttttt gagaaagata ttcaatctcg
     8521 atcttacctt tcccattttt ttcttggata gctacacttg taccaaattt atccatcaaa
     8581 cgatcttcgc tttctcggat ataatatggt ttttcctttg ctagccttgg gatttttttc
     8641 ttttcttttc catcattttg atttaactca gaaacaagct gttccagttg gcggacagtt
     8701 aaattttcag ttactgcacg attggctaat ttcaagatca atgttttatt ttttaaacct
     8761 aacagcgtac gggcttgtcc catagataaa cgctgatctt gtaccatttc cttgacaaga
     8821 tccggtaaag aaagcaagcg caaataattg gcgatataag gtctgctctt tcctaaacga
     8881 ctagctactt ctgcttgtgt tagtttcagg tttttcatca gcatctcata tgcttctgct
     8941 tcttctaacg gattcagatc ttctcgctgc aagttttcca gcactgctac ttgcatcatc
     9001 gcttcttcgt caaagtctct aacgatagca gggatcgttt ctttttcagc tagtttggac
     9061 gctcgaaaac gtcgctcccc tgcaataatc tcatatcctt ttactgcgga acggcgtacg
     9121 atgatgggtt gaaagacacc tgattgttca atagaattag ctagttcctg caaagatact
     9181 tcttcaaatg ttttacgggg ctgatacgga tttggtcgca gctcattcaa tggtagctgg
     9241 acaacggtat catcttttac atccaccgtc tctaagtttt ctaaatcttg aaacagtgca
     9301 tcgattcctc ggcctaatcc tttacttttc ttcacgactt accacttcct ttgccaatgc
     9361 ttggtagact tcagctcctc gagaacgtgg atcgtagtcg atgatcggtt ttccatgact
     9421 aggtgcttct gataaacgaa tatttcttgg aatgatcgtt tcgtaaactt tttcgcggaa
     9481 gtatttacgt acttcttcta cgacttcatt tcccagattt gttcgtgcat catacattgt
     9541 cagtaagact ccctcgatct ctaattctgg attaaagtgt ttttggacta aacgaaccgt
     9601 attcagtaat tggcttaatc cttccaatgc gtaatactca cactgaacag gtatcaaaat
     9661 cgaatcactt gctgtaaatg aattgattgt cagatggcca agagaaggcg ggcaatcgat
     9721 caaaatataa tcatactgac tgcttacttc tgctaaagat ccttttaatc ttgattctct
     9781 tgccatcatt gacgtcaatt cgatctctgc tcctgctaat tggagagtcg caggcacaat
     9841 actcaaattt tcgtgttcag tgatcaaagt tgcctcatca attggcaatt cattgactag
     9901 aacatcatag atgtctcttg tcacatcagg ttttctgatc ccgacaccac tggtagcatt
     9961 tccttgtgca tccatatcca ctagcaatac ttttttgcca aggctagcaa gacaagcacc
    10021 tagattcacc gtcgtcgttg ttttgccgac gccacctttt tggttcgcaa cagatattat
    10081 ttgtgccatc tcttctcctc ctatttgatt ggctgcttat taggcagtcc gggctttctt
    10141 gggtatttct ttggggttgg tttctttttt tgaataacga tgatatgccg ttgatcagag
    10201 acattcggca aggtaaccgc ctcttctttg aggaatttac cacctaataa agcaatcgct
    10261 tgttttgctt ctgtcaattc ctcttcactt tttgctgctt tcaatgcata aaaatagcct
    10321 tcttgtttag ccaagggcaa acacaattcc gctaacacat tcaaacgagc aaccgcacga
    10381 gcagtgacaa ggtcaaatga tgcacgaaag tgaggatttt gcccaaatgt ttctgcccgg
    10441 tcatgatata aggaagcatc gattcctaat aatcgggtta actcagataa gaaggttatt
    10501 cgtttattca gagaatcaac gatcgttatc tgcagttctg gaaaggcaat ttttaaaggt
    10561 atgctaggaa accctgcccc cgaaccaaca tcgcataaag ataaaggttg cgtaaagtct
    10621 acttcaaatg ctaatgtaag tgaatcgtaa aaatgcttca gatatacgtc tttttcatcc
    10681 gtaatagctg taaggttcat cttttcgttc cattcgacta atgtccgata ataaatagcg
    10741 aattgattca tttgatgatc ggtaagctct atcccttttt ctgccaagga ttggcgaaat
    10801 tcttctggta tcataaatat tcctttcatt gtgaaacagc aattgtttca cagattctct
    10861 ccctacttta acgcaaaatc tctagacatg caatccttcc atatggattc ttaaaaattt
    10921 gaaaagtaag aaaagccgat agactttttc tttctagtat gactcataaa atatacacag
    10981 aagagagaac tagctttgag caatttctgc aaaaactagt tctctcttct atttattatt
    11041 acgtattacg ctggttcact gactttcgca atcttccctt gttcgatata gaccattagg
    11101 atacttaggt ctgcagggtt tacgccactg attcggctag cttgggcaat tgtttctggt
    11161 tggattttct gcaatttttg ttttgcttct gttgctaatc cgttgattgc tgcgtagtcg
    11221 atgttttctg gaatcttttt cgcttccatg cgttttaatt tttctacttt ttccatggct
    11281 tttttgatgt agccttcata tttgatttgg atttctactt gttcgatttc ttttcgtgtc
    11341 aattcttcat tttctggaat aaaccgtaga agttctgcat aagtaatctc aggacgtctt
    11401 aaaaagtcgc ttgctagtac accatctttt aatggtgccg cattaatcgt tgctaaaaag
    11461 tcttggactt cttctgttgg tttgattcgt acattcatca aacgtttgat ttcttgttca
    11521 actgcttctt ttttcttcaa ataattcttg tattgatctt cttttactaa gcctacacgg
    11581 tgacccattt ctgttaatcg caaatctgca ttatcatgac gtaaaagcag acggtattca
    11641 gcacgtgaag tcagcaaacg ataaggttcg ttcgttcctt ttgttaccaa atcatcgatc
    11701 atgacaccga tgtaaccgtc acttcgtttg atcactaaag gttcttttcc ctgaactttc
    11761 aaagctgcat tgataccggc aatcagccct tgtccagccg cttcttcata accgcttgta
    11821 ccatttgttt gtccagctgt ataaagattt tcaacgactt tagtttctaa tgtcggacgg
    11881 agctggtgtg gctctactac gtcatattcg atagcatatc ctgtacgcat catttctact
    11941 ttttctaatc cagcaataga atgaagcatg ttgacttgaa catcctctgg taaagaagta
    12001 gataaacctt gaacatagac ttcttccgta tttaagcctt ctggttccaa aaataattga
    12061 tgacgtggtt tgtctgcaaa acgcacgatc ttatcttcga tggatggaca atagcgagcg
    12121 cctacccctt caacgatccc tgtaaacatt ggggcacgat gtaagttgtc tcgaataatt
    12181 tggtgagtcg tctcacctgt ataggtcagc cagcaagatt cctgatctag tttataggca
    12241 ctatctggtg tgctgaagct aaaatgattc ggctctttgt caccaggctg ctcttctgta
    12301 acagaatagt cgatcgtact tgattttact cgaggcggtg ttcctgtttt gaaccgttcg
    12361 atagcaaagc caagttcttt tagatgattc gctagtccaa tagaaggttg agagttattc
    12421 ggacctgatg aatatttcaa ttcaccgata atgatttctc cgcgaagtgc tgttccggct
    12481 gtaataacaa ctgctttggc ccggtagctc gctcctgtgg acgtcactac tccatgacaa
    12541 acaccatctt cgacgatcag ttcttcgacg attccttgtc ttagcgtcaa atttggttct
    12601 ttttcgatcg tatgtttcat ttctgttgaa taagcatgtt tgtctgcttg tgctcgcaat
    12661 gctcggacag ctgggccttt tcctgtgttc aacatacgca tttggatata ggttttatcg
    12721 atattcttac ccatttctcc gcctaacgca tcgatttctc gaacgacaac gcctttagct
    12781 ggtccgccta cagaaggatt acatggcatg aatgctacca tgtccaaatt tattgtcagt
    12841 aataatgttt ttgatcccat acgtgcagca gcaagtgcag cttctgaacc ggcgtgtcct
    12901 gcgccaacaa cgatcacgtc atacgcatct gcttcataat gttccaatcg tttgttcctc
    12961 cttttatttt cctaaacaaa attgactgaa taattgagtg attagctcat cttgtacact
    13021 gtcgccgaca acttctccta gatagtccca gcaacgcgtc atatctattt gaacgagatc
    13081 cacaggcatt cctgaatcaa tacctgcaat gacttcttca agtgagaggg aagctttttc
    13141 taacaacgcg atatggcggg tattagaaac ataagtagcg tctctttctc ctgtttctcc
    13201 gctgaagaat aaatcagaaa tagctgattc caaacgatct agtccgtcgt ttttagctac
    13261 ggaaattgaa aaaactggtt cattttcgat caatttcttc aatttttctt gttccagctg
    13321 tgctggcaaa tctgttttat ttagaagaat gatccgtttc aatccacttg tcgcttccaa
    13381 taattgttca tcttctgctg tcagtggttc gctttggttt agaacaagta agatcaagtc
    13441 tgcttctgct aatgcttttc ggcttctttc gaccccgatc cgttccacca catcttctgt
    13501 ttcccgaatt ccagctgtat cgattagctt gagcggtacc ccccgaacat tgacatactc
    13561 ttcgattaca tctcgagtcg ttcctgcaat atccgtaacg attgcttttt cttctcttaa
    13621 caaatggttt aacaaacttg atttgccgac atttggccgg ccgatgattg ccgtacttaa
    13681 cccttcccgc agaaccttcc cttgcttgga tgtagcaagt agcgcttgga ttctttgttg
    13741 gatcatctgc gctttttcaa gcaataactt cgtagtcaat tcttcgacat catcatattc
    13801 tggataatca atatttactt ctacttgtgc taatgtctct aaaatctctt gtctcaatga
    13861 gcggatcaaa gcagacagat tgccgtctaa ctgattaaga gctagtccca ttgctttgtc
    13921 tgtttttgcc cgaatcaaat ccatcacagc ttctgcctgt gaaaggtcaa cacgaccatt
    13981 caagaatgct cgttttgtga attcgcctgg ctcagctaat cttgcacctt ctcttaacaa
    14041 tagctgcaaa atttgattga ctacaacgat cccaccgtga caattgattt ctactacatc
    14101 ttcccgcgta aatgtctttg gtgctctcat cacggagacc atgacttcat cgacaagctg
    14161 attgctcttg ggatcaacga tatgtccata atggatcgta tgacttggta cttctgataa
    14221 tcgtttgttt ccagattgat aaactttatc tgctagttgc acagcttgat cgccacttaa
    14281 acgaacgata ctgattgcac cttctccagg tggggtagaa attgccgcaa tcgtatcaaa
    14341 ttctaaagta atttcagcca ttttttcact tcctttttca ttttgcgcac aaaaaaagtg
    14401 cccactccac cctttatgca caataaacgg tgaacttcgc actttgactg cttgttcttg
    14461 attaaattct ggtcatagat tatcacactt gctataagga atcaagtgtt taaaacaatt
    14521 agatgaagtt gagcctgttc tgcttccatt accttatatt taattgtcct tggatgtctc
    14581 tttgcgttct ttggtttatt cgaagagaag atactgtata aacaaggctt tatctttctt
    14641 aaaaaaaacg gtacactaaa tggtagcgct atctaaacta tacacttttg aaaggagaaa
    14701 atatgtgagc ccgttcagat ctgctgcatt ggaagaagaa agtgaccctc ggatcaacga
    14761 tgtcgtttta tctacaggga atatcaacca gaaatatatc gtccgcgata tcgtttttgt
    14821 tgtggaatgc ttagaagctg atttgtttga cccatctttt cccaaagatg accttttctt
    14881 aacaacgaag aggaaattaa agacgaaggt acttgaatat ggtgcgaatg cagtaatcaa
    14941 ctgtcatttt gagtatcagc aaaaaaaacg cgacggaaag tattttctgg aactttttgc
    15001 ttatggaaca gtgatccaat ttatccaaac aacgattggt taaatgaaac agacaaaaaa
    15061 agcggatcaa aactgaagac agtttcgatc cgcttttttc tatcaaagtt agtgactact
    15121 tcatcgtata ctctgataag aatgatttct agtaaaatat acttggtttg aaaaactttg
    15181 tcaacgtgat ttattcaaaa agtaatggaa tcaataatat tttttagcag gttctactac
    15241 taaataacga taaggttcct caccttccga atgtgttttt acatgttcat ctttgcttaa
    15301 tgcagcatgg atttgtttac gttcaaatgc aggcattggt tctaagaaaa caggctgccc
    15361 tgtccgtttt actttttcag ccgtgcgatc agctaaacgc tgaatgatct cttggcgctt
    15421 ttcacggtaa ttgcctacat tgactactac agacagctta tttcttgcta aacgatggat
    15481 gaagacttgt gccagatatt gcaatgcatt cagtgttttt ccatgtttcc caatcagtat
    15541 gccttgcttt tgtgtttcta aatggaaaac aaccatatta tttgattctc tttccatttt
    15601 gacaagagct ggagcatcaa gctgttttga aatttcagta agataaactg ccaattccgt
    15661 taaagctgct tcatcaccta gctcacttac ttcttctgtt ttttcttcaa gaatcgtttc
    15721 gttgactacc tcgatctcag ctgttggttc ttcttccaaa atttcttcta cagtctgttc
    15781 tactgtttca gaaacttttt cgctgatact tggctggatc gaaagccgtg cattctttcg
    15841 acccattcct aggaaacctt tttttccttc ttccagtatt tcgatttcga cttggtcttt
    15901 ggccaaaccc aaatcagcca gacctagttg gacagcttcg tctattgttg cagcttcata
    15961 aatcggcatt agcattacct cccctattat ttccgttttt tcttaggatt cattgctttc
    16021 ttaagagcac gttctctttc gcggattctc cgtgcttctt cttcacgctc ttttcgaatt
    16081 ttgaaagggt tgttgatcag cagcgtttgt acaacttgga aggcattgga aactacccag
    16141 tataatgaaa gaccgctggc taaattgaca cccatcacta aaatcattac aggcatcacg
    16201 aaattcatga tcttcattga tgcattcgat tcaatttgac tcatgctaga taaatacgta
    16261 cttgcaaaag taaagattgc tgctaaaatc ggcaaaataa atgttggatc cgcgttccct
    16321 aagttcaacc ataagaaatg cccttgtttc aactctggta cacgtgaaat agattgccat
    16381 aacgccatca agattggcat ttgtactaat aaaggaagac aaccagcata tggattgacg
    16441 ccattttctg catataaacg ctgctgctct tctcttaact tactttgtgt ttccggatct
    16501 cttgaactat attgttgctg cagtgctttt aatttcggtt gtaattcttg cgttttacgc
    16561 atgctctttg tttggaaatg catcaacggc aataggatca cgcggatgat cagtgtaaat
    16621 aaaatgatcc ctatccctgc attaccaaat gacaacgcct tgatcgcctc agcaaagtaa
    16681 taaacaatat aacgatccca aattcctgta ctctgtgcgc tgacttcccc agttccgcaa
    16741 ccggataaga cgatgaccaa actaacgata ccggccatca aaagtaaacg tttgtatttc
    16801 ttcacttact cttttcctct ctgtcgatta tttttgcaag ttttaagacg tggactaaat
    16861 tggagcgaac ctcatcataa gtcaacccct tcacacttgg tctagcaatc acaataaaat
    16921 ccaactccgg atcaatttct tcttttatag aataaactgc tgctcggatt tttcgtttga
    16981 cttcattgcg gtttaccgcg ttgccgacct tttttcctac agataaacca actcgaaaat
    17041 gaggctgtcc cggtttttcc aaacggtaaa cgacgaattt gcggttagca aaagaatctc
    17101 ccgtatggaa cacggcttga aactctcgtt ctttttttac tcgatacgct tttctcatta
    17161 gttttctttc cttttctatc tctcacttac gctcataatc ataccataat tacgattgtc
    17221 ctttcatcat ttccctaaaa aagagtataa aaaaaaccac tgaaacccca gtggcctaag
    17281 ctgaaagaac ttttcttcct ttgcgacgac ggctagctaa cacacgacgt ccatttttag
    17341 tactcatacg tttacggaat ccgtgaactt tttgacgttt acgtttattt ggttggtatg
    17401 ttcttttcat atattccacc tccaaaatgt tcttatctat tttataaaca cagacatact
    17461 ttgatagtat aacgacaaag tagtgatttt gtcaatataa aatagaagat cgattgttaa
    17521 aacttatcca caagattatt tttttctatg ggaatcctat gtggaaaaag ttatgcacag
    17581 ggattatcca cagataataa aaggctggtt ttacacagaa aacacacgtg taaaaaaagt
    17641 aatccacaat caggcgattt cctgtgtatt ccgtctccta actattggta tatctgtatt
    17701 ttttatccac agacgcaaga ggaaatctat tggtttttac gagttttcca cctgtgcatt
    17761 agtggtgtgg aaaacttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    17821 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    17881 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    17941 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18001 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18061 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18121 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18181 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18241 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18301 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18361 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18421 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18481 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18541 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18601 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18661 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgccttgttt ctcgctttgc
    18721 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    18781 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    18841 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    18901 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    18961 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19021 ttatcacatc caattgaaag atctcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19081 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19141 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19201 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19261 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19321 aaaagttata cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19381 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19441 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19501 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19561 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19621 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19681 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19741 tttactttag aagttttaga aaataaacaa gtagcgatca cttctggaaa agcgaatttt
    19801 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    19861 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    19921 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    19981 ttattagctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20041 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20101 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20161 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatccaga taccaatcgt
    20221 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20281 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20341 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20401 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20461 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20521 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20581 gtacgtacaa attaacaatg attttcaatg ttcttgaaaa tttaattgaa aagaaataga
    20641 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttattttt
    20701 gtttaaatca ccttttttag attaaatcgt cttatatgga aaaatatatg gataaatttg
    20761 ttttattgcg aaaaaaaagg tataatagag tatactttta ataatgaaaa tgagggatgg
    20821 gcattgaaac aacaagtcat tctaaatacg gaattcatga cgttgggcca aatgttgaaa
    20881 gaagtcacag ttatcggtag tggcggacaa gcaaaatggt atttggcaga aaacactgtg
    20941 ttagtcgatg gcgaaccaga aaatcgtcgt ggacgcaaac tttatcccgg catgatggtt
    21001 gaagttccag aagtaggaac tttttttatg gtaaaaaaag gaaacgacga taatgaggct
    21061 gaataagctg tatttaaaaa attatcgaaa ttacgaagag ctgaacatcg aattttccaa
    21121 gaacctcgtc atctttttag gagaaaatgc gcaaggaaaa acgaatcttt tggaaagtat
    21181 ctacgtatta gctatgacgc gaagtcatcg gacaagtagt gagcaggaat tgattggctg
    21241 gactgacgat caggcgatga ttcaaggaga gatcacaaaa ggttcatcca ctcttccatt
    21301 agaaatctta ttatctaaaa aaggccgaaa aaccaagatc aaccatatcg aacagaaaaa
    21361 gttaagtact tacgtgggac aaatgaatgt cattttattt gcaccagaag atctttcttt
    21421 agtaaaaggc agcccgcaga tcaggcggaa gtttttagat atggaattag gccagatcaa
    21481 tccaatctat ctttatgatc ttgtccaata ccaagcaatt ttgaaacaaa gaaaccagta
    21541 cttgaagcaa ttgaatgaaa aaaaacaaac tgatttgctt tatttggata ttttgtccga
    21601 acaactagca gcgtttggca gcaaagtatt gaaagcaaga gcacagttcg tcaagcgatt
    21661 ggagttttgg gctaattctt tgcatcagca aatcacccat caaaaagagc agctggaaat
    21721 cgagtatctc accgcagtcg attctttaga aacacatacg caagagcaaa tccaagaaca
    21781 atttctcgca cttttgaacc aaaataaaaa gaaagacctt tttcggggaa caacgacagt
    21841 tggtcctcat cgtgacgatc tttccttttt tattaatcag aaaaatgtgc agacttatgg
    21901 atcgcaagga cagcaaagaa caactgcact aagtgtcaaa ttagcagaaa tcgatttgat
    21961 taaagaagag acaggggaat atccaatcct tttgttagat gatgtgatga gcgagctgga
    22021 tgataatcgt caactccatc tgctagaaac aatcgaagga aaagttcaaa cgttcttaac
    22081 aacaacgaca cttgaccatg taaaaaataa aatgactgtt gaacctgaga ttttttatgt
    22141 tcaacaaggg aaactaaaag gagaagaaac tgaatgacag aagaaagaag tttagtagaa
    22201 cgcgctaaag agtatgatgc cagtcagatt caagtacttg aaggacttga agccgttcgt
    22261 aaacgacctg gcatgtatat cggttcgact agttctgagg gtctgcatca ccttgtttgg
    22321 gaaattgtcg ataattcgat cgatgaagta ttagcaggtt ttgcaacgaa aatccatgtg
    22381 attattgaaa aagacaacag tatcaccgtt attgacgacg gtcgggggat acctgtagat
    22441 atccaggcaa aaactggacg tcctgcagtt gaaacggtct ttactgtttt acatgctgga
    22501 ggaaaattcg gcggtggtgg gtacaaagtt tctggtggac ttcacggagt aggatcttct
    22561 gttgtaaacg cgctttctac acagcttgat gtcaaagtat acaaagaagg aaatgtgtac
    22621 tatcaagaat atcgtcgtgg agctgtagtg gacgacttaa agattatcga acaaacggat
    22681 cgccatggaa caacggttca ctttacgcca gaccctgaaa tttttacaga gacaactgag
    22741 tttgattttt caaaattggc tacccggatc cgtgaacttg ctttcttgaa ccgcgggatg
    22801 cgtatatcga ttgaagacaa acgagaagaa gaaccagtca tcaatgaata ccattatgac
    22861 ggcgggatca aaagttatgt cgaatacttg aatgcaaaca aaaccgtgat ttttccagaa
    22921 cctgtatatt tggaaggtga acagcaagat atcgcagttg aagtctctat gcaatataca
    22981 gacggctacc attccaatat catgagtttt gccaacaata tccatacgta tgaaggtgga
    23041 acacatgaat caggattcaa gactgcttta actcgtgtga taaatgatta tgcccgaaaa
    23101 caaaagctga tgaaagaaaa tgacgacaac ttgaccggtg aagacgtgcg agaaggattg
    23161 acagctgtta tttctatcaa gcatcctgac cctcaattcg aaggacaaac aaaaacaaaa
    23221 ttgggcaatt ccgaagtacg gacagtcact gatcggttat ttagcgaaca tttcatgaaa
    23281 ttcttgctgg aaaacccaag tgtgggccgg caaattgttg aaaaaggatt actagcttcc
    23341 agagctcgtc tagcagcgaa acgtgcgcgt gaagtaacga gacgtaaagg tgctttagag
    23401 attagtaatc tgccaggaaa attagcggac tgctctagca acgatcctga aaaatgcgaa
    23461 ttgttcatcg tcgaaggaga ttcggccggc ggatcagcta agcaaggtcg taatcgagag
    23521 tttcaagcca tcttgcctat tcgtgggaaa atcttgaatg ttgaaaaagc aagcatggac
    23581 aagatcttgg caaatgaaga gatccggtct ttatttactg ctatgggtac agggtttgga
    23641 gaagattttg atgtatcgaa agctcgctac cacaaattag ttatcatgac tgatgccgat
    23701 gtcgacggcg cgcatatccg tacattgctg ctgactcttt tttatcgtta catgcgtcct
    23761 attgttgaag ctggatacgt ctatattgct cagccacctt tatacggggt aaaacaaggg
    23821 aagaatatta cgtatgtaca accaggaaaa aatgcagaag aagagttgaa acaagtcgtt
    23881 gcttcacttc ctgcctcacc aaaaccaagc gttcagcgtt ataaaggact tggagaaatg
    23941 gatgatcatc aactatggga aacaactatg gacccaagca atcggatgat ggcccgcgtc
    24001 agtgtggacg atgctattgc agcagatcag atatttgaaa tgttgatggg ggatcgagta
    24061 gaaccccgtc gtgcattcat cgaggaaaat gcacactatg tgaagaactt agatatttaa
    24121 tcatgaagga ggaaaaagaa tgagtgaaga aatcagagaa aacatccatg atgtcaatct
    24181 aaccagcgaa atgaaagact ccttcatcga ttatgcgatg agtgttattg tcgcacgtgc
    24241 acttcctgat gtcagagatg gtctgaaacc cgttcatcgc cgtattttat acggcatgaa
    24301 cgaattaggt gtaacaccgg ataaagccca taaaaaatct gccagaatcg tcggagatgt
    24361 catgggtaaa taccatcctc atggagacat tgcgatctat gagtcaatgg tacggatggc
    24421 acagccattc agctaccgtt atatgctagt ggatggtcat ggaaactttg gttctgttga
    24481 cggtgacggt gccgccgcta tgcgttatac cgaagcacgg atgagcaaaa tcgctacaga
    24541 aatgctgcgt gatatcaata agaacactgt tgatttccaa agcaactatg atgatacaga
    24601 aaaagaacca gttgtactac ctgctcgctt cccgaatctt ttagtgaacg gaacaacggg
    24661 gatcgccgta ggtatggcca cgaatatccc acctcataac ttgtctgagg tagtagcggc
    24721 tatcgatttg ctgatggata atcctgatgt gacgaccaat gaattgatgg aagtattacc
    24781 tggaccagat tttccaacag gtggtttggt tatggggaaa tcaggaatcc gaagagcgta
    24841 tgaaacaggt aagggttcta ttaccgtacg tgcaaaagtt gagattactg agatgccaaa
    24901 tggtaaagaa cggatcatcg tgacagaatt gccttatatg gtcaataaag caaaattgat
    24961 cgaacggatt tctgaactgc acagagacaa gcgtatcgaa gggatcacag atttgcggga
    25021 cgaatcttcc cgtgaaggta tgcggatcgt cattgacatc cgtcgtgacg ccagcgcatc
    25081 cgttatcttg aataacttat ataaattgac atccttgcaa aattcatttg gattcaatat
    25141 gttggcgatc gaaaaaggtg tgccgaaagt tttgagcttg aaacaaatcc ttgaaaacta
    25201 tatcgaacat caacgcgaag tcatcacacg acggacggtc tttgaaaaag aaaaagcaga
    25261 agcaagagca cacatcttag aaggtttgcg tattgctttg gatcatatcg atgaaatcat
    25321 tgcgattatc cgcgggtcta aatcagatga cgaggcaaaa gcaacaatga tcgaacggtt
    25381 cgatttatcc gatcgccagt ctcaagctat tttagatatg cgtttacgcc gattgaccgg
    25441 tttggaacgg gaaaaaatcg aaaatgaata ccaagaactc ttaaaactga ttgaagattt
    25501 aactgacatt ctggcaagac cagaacgtgt tacagaaatc atcaagaatg aattagcaga
    25561 cttgaatcaa cgatttggtg ataaacgacg cacagaatta ctagtcggtg aggtcttaag
    25621 tctggaagat gaagatttaa tcgaagaaga agaaatcgtt attacattga caaacaatgg
    25681 ttacatcaaa cgtttggcaa ataatgaatt cagagctcaa cgaaggggtg gacgtggtgt
    25741 ccaaggaatg ggtatccaca atgacgactt cgtcaaaaat ctggtttctt gttctaccca
    25801 tgatacattg ttattcttta cgaataacgg aaaagtgtat cgggcaaaag gatacgaaat
    25861 tccagaatac gggcgtacag ccaaaggaat cccaatcatc aatttactag gtatcgattc
    25921 gagtgaaagc atccaggcaa tcattgcggt gacgggagaa gcagaagaag gccactatct
    25981 cttctttacg acgcgtcaag gtacagtaaa acgtacttct gtcactgctt ttgctaacat
    26041 ccgaagtaat ggtctgatcg caattggttt gaaagaagac gatgagctcg tcaatgtgct
    26101 actgacagat ggtcaatcta atatcattat tggaacacat aacggctact ctgtcacttt
    26161 caaagaagaa gcagtccgcg atatgggacg tacagcttcc ggggtcagag ggatacgcct
    26221 gcgtgaggaa gattatgtcg ttggggcagc cttaatgaag gaaaatcaag aagtattagt
    26281 gatcacagaa aaaggttacg gaaaacggac aaaagtatcg gaatatccag tgaaaggccg
    26341 cggaggtaaa gggatcaaaa cggcgaacat cactgaaaaa aatggtccac tagctggatt
    26401 gaccactgtt tctggagatg aagacatcat gctgattaca gataaaggtg tcattatccg
    26461 tttcaacgta tcgactgttt ctcaaactgg acgttcaaca ttaggcgtac gtttgatgaa
    26521 gatggaagct gatacgaaag ttgtcacgat ggcagcagtc gaaccagaag ctgcagaaca
    26581 aacagttgaa gaacaaggat cagaagaata accatcaaga ctaagtgtgt aagctagcaa
    26641 gaataaccga ttaaaaaatc tggttattcc tgctggcttt tttgattagt tgaatttctc
    26701 ttaaaatatt cgaaactgtt cattctgtat tgcttttgac caaaatagag tgtataatta
    26761 gagcttgtga gtagtctaat taattagata actctccttg ctcttaggaa cctaagagcc
    26821 gaaagtccac agggaggtga atatcaatgg aaaacacgaa atatgaaatc atgtacatta
    26881 ttcgtccaaa cattgatgaa gaagcaaaaa ctgctttaat cgaacgtttc gatgcaatct
    26941 tgaaagataa cggagcagaa gttatcgaat caaaagattg ggaaaaacgc cgtttcgctt
    27001 atgaaatgaa cggttaccgt gaaggtatct atcacatcgt taaagtatct tctccatcat
    27061 cagcaaatgc tgtcaatgaa tttgaccgtc ttgctaaaat caacgacgat atcattcgtc
    27121 acatgattgt taaagaagaa gcttaattgt tgtttcatgt gaaacaatag aaaacgatga
    27181 gaggagatga ctattttgat taataatgtt gtattagttg gacgtctgac gaaagatcca
    27241 gatttgcgtt acacagcaag tggtacggca gtcgcaacat ttactttggc tgtgaatcgt
    27301 aattttacaa accaaagcgg caatcgcgag gctgatttta tcaactgtgt gatttggcgc
    27361 aaatcagcag aaactttagc aaactatgct cgtaaaggaa cacttttagg tgttactgga
    27421 cgtatccaaa ctcgttctta tgataatcag caaggacaac gtgtatacgt gacagaagta
    27481 gtagctgaca acttccaatt gctggaaagt cgttctgcat ctgaaaatcg ccaacaaagc
    27541 ggcggattcc aaagttctgg tcaatcagct ggcggatttg gcggaaacaa taactctaat
    27601 caaacatctc aatcatccaa cggtatgcct gatttcgacc gtgatacttc tgacccattc
    27661 ggctcaagtt caacgatcga catttcagac gatgatttac cattctaaac gaatttgata
    27721 ggagggaaat agaatggcac aacaaagaag aggcggacgt aaacgtcgta aagtagacta
    27781 cattgctgct aaccatattg aatatatcga ttataaagat atcgaattac taaaaagatt
    27841 tatttcagaa cgcggtaaaa tcttgccacg tcgtgtaact ggtacaggcg ctaaaaacca
    27901 acgtaaaatt actgttgcaa tcaaacgcgc tcgtatcatg ggcttgctac ctttcgttag
    27961 cgaagactaa taaatcctag gaattgaatg actgatcctt ttgatcagct attcaattcc
    28021 tttttttctg taaaaataac ctctattcgt ttagtcgctc gaatgacgaa agttatggta
    28081 aaatcaaatt agtcatatat gggaggaaaa ttatggaaaa taaaaacaat catttatccc
    28141 cgaaacctct cttccttatc ctgtttatat taatcgaagt attggtagtc ttaattttac
    28201 catttcgttt tgttagcgct tcggtcattc tattgatgaa tttatggggt gttcgctatt
    28261 ggttgaaaat gaaacgttgg cttattttaa ataaacgtga aaaaatccag caggcttcga
    28321 ctgtagctga aaccaatcta gcttatgtct cagaagtcat gcctgtagga gtgattgctt
    28381 atcagccatc aagccaaaaa atcgaatggc tcaatccatt agcattgaaa atcaaagatc
    28441 aaagtggatt aacagaggaa gaattgctag atactttttt tactgcaaaa gaaaaaaaga
    28501 aaaaccaagt ctatctagca gataaaacat ttcagtttga tatggataca gtaaagggtg
    28561 ttgtttattt taatgatatt acccaaaacc agttgttaaa actccatcag acgaacagtc
    28621 agccggtgat tggtatttta tctattgata actatgcaga tgccattgat aaattagatg
    28681 acaaagagat ttcttatttg aactctttcg tcactacact agtttctgac tggatgaatg
    28741 aataccatgt ctttttcaaa agaatcaacg cagaacggtt tttcttcgta gcacagatga
    28801 tcgatctgaa aaagatgatg gataaaaaat ttgatttgct ggatcgcttt cgagcagaag
    28861 ctgaaaaaca gagctcgcct atcaccctta gtatggggat tgcttatggc tcaagaaccc
    28921 tcgatgaaat cggtggagaa gctcagaata atttagatgt tgctttagtc cgtggaggcg
    28981 accaagttgt cgtgaaagag gtaaaagaag gagcaaaacc tgtttattat ggggggaaat
    29041 ctgctaagaa tgtcaaacgc acgcgtgttc gttctcgagc gatgagtacc gctttgcgtc
    29101 ggatttttga tgaaacaggc gatgtgttta tcatggggca caagtttccg gatatggatg
    29161 ctttaggctc tgcttttggt gtcagttgtc tggcacgctt caaccagaaa aaagcttaca
    29221 tcgttatcaa tgagaacgag atcattccag atgtagaacg gtgtcttgaa gaaatccata
    29281 agcatcctga attagaaatg caactaatct ctccagaacg tgccatagag ctgaaaaaag
    29341 aagaggacct cctcgtgatg gtggattacc ataaaccttc tctatcgatc tctcagggcc
    29401 tatatgagca atttgataag attgtgatca ttgatcacca tcgtcgtggg gaagagtttc
    29461 caagtaaacc tctgctgact tatattgaat cttcagcttc ttcagcttca gagctagttt
    29521 ctgagctgat ccaataccaa agcagcaaaa caaatcgctt agatcgtttt gaggccacat
    29581 tattgcttgc agggatggtt gtagatacaa atagtttcaa tgtccgtaca actgcacgaa
    29641 cttttgacgt tgccagctat ttaaggtctt gtggagcaga cgcatcctta gtacaatatt
    29701 tattgagctc ggatttagcg acatacttgg agatcagcaa tttgattgct ggaagcgact
    29761 atgtgacttc tgatattgtt gtggcggcag ggacagacga aaaagagtat aatagtgtta
    29821 tagcagcaaa aacagcagat acattgcttt cgatgatcaa tatcaatgca gctttcgtca
    29881 ttacaaagcg gacagacggc ttgattggga tcagtgccag aagtaccggc acgatcaacg
    29941 tccaaatcat catggaatcc ttaggtggcg gaggacactt cacaaacgca gctactcaac
    30001 tggaaaatac gacagttgag gaaacaaaac agaagctatt tgctgcaatc aaagaaaata
    30061 tgaatcaaat atatgataag gagtaatcca aatgaaagta atttttttac aagatgtaaa
    30121 aggaaaaggt aaaaaagggg acatcaaaga agttccagca ggttatgcac aaaattatct
    30181 aatcaaaaat aacttggcaa aagaagcaac gaaaagcagt atcagtcagt tagcaggaca
    30241 aaagaaagca caagaaaaac acgaagctga aatcttggaa gaagctaaaa agttaaaaga
    30301 attcttggaa aaagaagata ctgtagtcga attgaaggcg aaagcagggg aagacagccg
    30361 tttgtttggt tcgatccctt caaaacaaat tgctgaaggg ttaaacaaac aatacaaaat
    30421 caaattagat aaacgaaaaa tcgaattaga aaatccgatc cgttcactag gctacacaaa
    30481 cgtacctgtt aagcttcatc atgaggtgac ggctacgatc aaagttcatg tcgtacaaga
    30541 ataacaaatc ttgatagcga tgttcagctg gtaagtataa ccagaaggaa aaaagacaaa
    30601 ccgaaattta tctgagaaaa cagctgcagc aatgaaagca aaagctgcaa atcgatttca
    30661 gattgatttc ggtttctttt ttgggaacag caaaatagca taaagaaaac gagtataata
    30721 aaagagaact atttttttat tacactttcg gtacgaatga tgacttttct ctcattttct
    30781 tgtaaaatga agcaattgaa gacaaggagc gatacgtatg aatgaagtgt ggcaggatcg
    30841 aatcccaccg caaaatattg aagctgaaca agcggtttta ggctctgttt ttcttgacgc
    30901 agaaacgatc attgatgcca tggagtacat agagccaaaa gacttttatc gtcgtggcca
    30961 tcaaattatt tttgagacaa tgatcgagtt aaatgatcgt aatgaagcga ttgacgtggt
    31021 tactgtcaaa gaccggctgg aacaagccaa tttgttagaa gatgccggtg gtttaagtta
    31081 tctctcagac ttggcattag cagttccgac agcagcaaat atcgtctact atgcgaaaat
    31141 cgttgaagaa aaatcattgc tgcgtacatt gatccagaca gcaacaggaa tcgttacgaa
    31201 aggattcgag caaggagaag aagttcaaac aattttagat gatgccgaac gcagtatctt
    31261 ggaggtttcg gaaaaaagaa atcgaagcgg ctttttatct attgctgaag tactgaactc
    31321 cacgattgaa aatatcgatc gactagctca aaacaatgaa gaaatcacag gtctaccaac
    31381 tggctatcaa ggtctggata aaatgacagc aggtttccag cccgaagaac taatcattct
    31441 tgctgcacgt ccagcggtag gtaaaacagc gtttgcattg aatattgctc aaaatgtagg
    31501 aacaaaaaca gatcgttctg ttgcgatatt tagtttggaa atgggggcag aatctcttgt
    31561 aaatcggatg ctttgtgcag aaggttcgat tgaggccagc catttacgta caggtcagct
    31621 ttcggaagaa gaatggtcga atctgatcgt tgcgatgggg agtctttctc gagcaaatat
    31681 ttttatcgat gatacaccag ggatcaaaat ctctgaaatc cgtgcgaaat gtcggaaact
    31741 agcgcaagaa aaaggcaatc taggcttgat attgatcgat tatttgcagt tgattgaagg
    31801 taacggtaaa gagaaccgtc aacaagaagt atcagatatc tctcgccaac tgaaaaaact
    31861 ggcgaaagag ctgaaagtac ctgtcattgc tctttcacag ttatctcgtg gagtagaaca
    31921 gcgacaagac aaacgaccag tgctaagtga tattcgtgaa tccggatcaa ttgaacaaga
    31981 tgcggacatc gtagccttct tgtatcgaga tgattattat gaaagagaag gcggagatga
    32041 cgatgatgga aacgagccaa aaaatgacaa cgtcatcgaa gtcatcatcg agaagaaccg
    32101 aagcggtgca cgaggaacag ttgaactact gtttatcaaa gaatacaata agttttcgtc
    32161 gctttcgcca agagaagaat tttaaagaag aggttgtgag ccttgagcaa tcccgagagc
    32221 tctcgtaaga agatgcaagg agtaaccgca ggaacgacta gagtacttaa tttaaacaga
    32281 tctccaaagg gattgtgaca aaagtcttgt cacagtccct ttttccgaat aaacggtgtt
    32341 caatcagctg acccttggta ttagctcagc aaacgtcaaa atatgaggaa ctattttgac
    32401 gtttgtttct ctaatactca ggtcaaaacg ctgatcttac gacctctttt ccttaaacgg
    32461 tgttctcctg ccaactcctc ggtcacaagt cacaatatca tcaaacatga gaagcagttt
    32521 tttgaaattg ctccttgtga ctcagagtta aacggcaggc tcacaacctc tttcttaaac
    32581 ggtgttcaaa agcttgcatc tgcggtaata cgcccaatca aacgaaaaat atgagaagct
    32641 atttttgttt ggctgttctt attacttgat gcaggacagc tttttcacaa cctctgattc
    32701 acggtgttcc aaaagtagct tcttcgaaaa ataagtcgaa atttcacaaa aatttgagaa
    32761 gcaattttcg tacattcctt cttatttctt gaagctgacc acttctgtta caacctcttt
    32821 tttaataacc attctaaaaa gataaagttc gttttttaag cgtttttata aaataaaaat
    32881 aaaaatcatt cgattttatt tgaaatatgt atctattatt gatacaatgg ttcaggatta
    32941 aataatatag aacgaggtgt tcacatgtca tctgtagtag tagtaggtac gcaatggggc
    33001 gatgaaggga aaggaaaaat cacagacttt ctcagtgaaa atgctgaagt gattgcacgg
    33061 taccaaggtg gcgacaatgc agggcacaca attaagttta acggtgtgac ttataaactg
    33121 catttgattc cttctgggat tttttataaa gacaagatca gtgtgatcgg aaacggcgtt
    33181 gtagtcaatc ctaaatcatt ggttaaagaa ttagcttatt tacatgaaaa aggtgtagaa
    33241 acaagtaatt tgcgtatttc tgaccgcgcg cacgtaatct tgccttatca tatcaaattg
    33301 gaccaattac aagaagatgc taagggcgaa aataagattg gtacaacgat taaaggaatc
    33361 ggacctgcct atatggataa agcagctcgt gtaggtatcc gtattgcaga cttattagat
    33421 aaagaaattt ttgaagaacg tcttcgtttg aatctagatg acaaaaaccg tcaatttgta
    33481 aaaatgtttg attcagaacc acttgatttt gacgatattt ttgaagaata ttatgaatac
    33541 ggacaacaaa tcaaacaata cgtcacagat acttccgtta tcttgaatga tgctttggat
    33601 gcaggcaaac gcgtgttgtt tgaaggcgca caaggtgtaa tgctggatat cgaccaggga
    33661 acttatcctt ttgttacttc ttctaaccca gtagccggtg gggtaacaat cggaagcggt
    33721 gtagggcctt caaaaatcaa taaagttgtc ggcgtctgca aagcctatac gtcacgtgtc
    33781 ggtgatggac catttccaac tgaattattt gatgaaacag gagaacaaat ccgcgaagta
    33841 ggacgagaat acggtacgac aactggtcgt ccgcgtcgtg taggctggtt tgattctgta
    33901 gttatgcgcc attctaaacg agtttcaggt attaccaacc tatctttaaa ctcgatcgat
    33961 gtattaagtg gattggaaac agtaaaaatt tgtacggctt atgaattaga tggcgaacta
    34021 atctaccact atccagcaag cttgaaagag ttgaaccgct gcaaaccaat ctatgaagaa
    34081 ttgccaggct ggtcagaaga cattacagga tgcaaaacac ttgcagaact gccagaaaac
    34141 gcacgtaact atgtacgtcg tatctcagag cttgttggtg tacgtatctc aacattttct
    34201 gtcggacctg atagaacaca aacaaacatc ttagaaagcg tctgggcgca aatctaagga
    34261 taaaaacgac gactgaatca ggacgttctt accagagcga gtcgaagtgt ttatctatac
    34321 gataataata acttgaagag gtagtgaaag agacgtttag ccttattgcc gataggctgt
    34381 ctcttgaaca ctgtttattc agaataaggg actgtgacaa aa
//
LOCUS       DADVXE010000026        32533 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.026, whole genome shotgun sequence.
ACCESSION   DADVXE010000026 DADVXE010000000
VERSION     DADVXE010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.026"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            131..505
                     /locus_tag="KB913_001330"
     CDS             131..505
                     /locus_tag="KB913_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6819702.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="KB913_001331"
     CDS             complement(619..1248)
                     /locus_tag="KB913_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6819703.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="KB913_001332"
     tRNA            complement(1382..1454)
                     /locus_tag="KB913_001332"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="KB913_001333"
     tRNA            1668..1741
                     /locus_tag="KB913_001333"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="KB913_001334"
     CDS             complement(1879..2043)
                     /locus_tag="KB913_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819704.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="KB913_001335"
     CDS             2338..3666
                     /locus_tag="KB913_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBB6819705.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="KB913_001336"
     CDS             3868..4701
                     /locus_tag="KB913_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBB6819706.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="KB913_001337"
     CDS             4717..5454
                     /locus_tag="KB913_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBB6819707.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="KB913_001338"
     CDS             complement(5609..6577)
                     /locus_tag="KB913_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBB6819708.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="KB913_001339"
     CDS             6809..7642
                     /locus_tag="KB913_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBB6819709.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="KB913_001340"
     CDS             7676..8515
                     /locus_tag="KB913_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6819710.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="KB913_001341"
     CDS             8541..9101
                     /locus_tag="KB913_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6819711.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="KB913_001342"
     CDS             9300..11021
                     /locus_tag="KB913_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBB6819712.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="KB913_001343"
     CDS             11186..12328
                     /locus_tag="KB913_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6819713.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="KB913_001344"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="KB913_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBB6819714.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="KB913_001345"
     CDS             14128..14775
                     /locus_tag="KB913_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBB6819715.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKLLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="KB913_001346"
     CDS             15168..17813
                     /locus_tag="KB913_001346"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBB6819716.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="KB913_001347"
     CDS             18123..19436
                     /locus_tag="KB913_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBB6819717.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="KB913_001348"
     CDS             19426..20079
                     /locus_tag="KB913_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6819718.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20826
                     /gene="radC"
                     /locus_tag="KB913_001349"
     CDS             20134..20826
                     /gene="radC"
                     /locus_tag="KB913_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBB6819719.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20976..21176
                     /locus_tag="KB913_001350"
     CDS             20976..21176
                     /locus_tag="KB913_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6819720.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21430..23109)
                     /locus_tag="KB913_001351"
     CDS             complement(21430..23109)
                     /locus_tag="KB913_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBB6819721.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23111..23323)
                     /locus_tag="KB913_001352"
     CDS             complement(23111..23323)
                     /locus_tag="KB913_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBB6819722.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23716..25446
                     /gene="efrA"
                     /locus_tag="KB913_001353"
     CDS             23716..25446
                     /gene="efrA"
                     /locus_tag="KB913_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBB6819723.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25443..27203
                     /gene="efrB"
                     /locus_tag="KB913_001354"
     CDS             25443..27203
                     /gene="efrB"
                     /locus_tag="KB913_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBB6819724.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27298..27495
                     /locus_tag="KB913_001355"
     CDS             27298..27495
                     /locus_tag="KB913_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819725.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27648..28133
                     /locus_tag="KB913_001356"
     CDS             27648..28133
                     /locus_tag="KB913_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBB6819726.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="KB913_001357"
     CDS             complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="KB913_001357"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBB6819727.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29010..29537
                     /locus_tag="KB913_001358"
     CDS             29010..29537
                     /locus_tag="KB913_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819728.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            29628..30365
                     /locus_tag="KB913_001359"
     CDS             29628..30365
                     /locus_tag="KB913_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBB6819729.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30369..31286
                     /gene="miaA"
                     /locus_tag="KB913_001360"
     CDS             30369..31286
                     /gene="miaA"
                     /locus_tag="KB913_001360"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBB6819730.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31288..32517
                     /gene="hflX"
                     /locus_tag="KB913_001361"
     CDS             31288..32517
                     /gene="hflX"
                     /locus_tag="KB913_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBB6819731.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10771 a         5522 c         6874 g         9366 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaagt tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tctggtaatg ttattccatc gcagcaggat
    20701 atgaatttta ccaaaaggat acaaaagtgt ggagaaatga tggggatcac tgtactggac
    20761 cacttgatca tcggacgcaa acgatatttt agtttgagag aagaaggaat gatggaagag
    20821 aagtaagttg ctttcttgca aaaaaaatga agcaagtgta caattatatt gtaattttgt
    20881 ttgggaatag aagttgaaac atctgttgca cctctatcgt acacgagcaa tgttacaatt
    20941 taaattagtg cttttggcac gaggaggata ttattatgga aaacggaaca gtaaaatggt
    21001 tcaacgctga aaaaggattt ggatttatct cacgtgaaga tggaagcgac gtattcgttc
    21061 acttctcagc tatccaaggt gacggattca aaacattaga agaaggtcaa gcagtgactt
    21121 tcgacgttga agaatcagac cgcggcccac aagctgcaaa cgttgtaaaa gcttaatttt
    21181 atctgtaaat caaattgatg gtagacatca atttttacga gagaacaaag cgagtaacaa
    21241 aaatacctgc cacaagagac aatttctctt gtggcaggta tttttttgta tgaaaaagta
    21301 aataaattta agaggctatg aaagagccac cttgtatcaa ggaataagaa caaacaaaaa
    21361 tggcttctca tgtttttcat ttgttttctc ttatattcag gacaaggtgc tgatttcata
    21421 acctcttatt tattcttcat ctggtgtcat taccattggc aaaatcattg gatgtctttc
    21481 tgtacgttcg aataagaaag gctgaagcgc gccagtcatc gcttctttca atttatattc
    21541 tgaacagtca ggtccattca aacattctct taaagcgtgg aataagattc gctgagcttc
    21601 attgatcatt tctcctgatt ctcgcatgta gacaaatcca cgagagagaa tatctggacc
    21661 agccaagatt tcttttttct tgatatccac tgtcgcgaca gctaatacaa gaccttcttc
    21721 tgaaagcagg tgacggtcac gtaaaacgac attaccaata tcaccgatcc cgctaccatc
    21781 gatatacaca tctccagcca caaaatgccc agcaggacgc gcagaatcgc tagttaacgc
    21841 taaaacatcg ccattttcca tgatgaagca gttttctgca ggaacaccta catcttgtgc
    21901 tagagaagca tgtactttca acatgcggaa ttctccgtgg acaggaataa aatattttgg
    21961 cttcatcaaa cgaagcatta atttttgttc ttcttgtcca ccgtgaccgg aagtatggat
    22021 gttattgatt tttccgtgaa tcacttctgc accagcttca gacagcaaat tgatcaaatg
    22081 attgacactt gttgtattac caggaatagg tgaacttgaa aagatcactg tatcgtctgg
    22141 ctggatttgg atttgacggt gagtaccatt cgcgatgcgg ctcaacgcgg ccatcgcttc
    22201 tccttgagaa cctgtacata ggatcatcgt ttcattggca ggcaagcgat tgatttcgtg
    22261 tgcatctaca aatgtgccgt ctggaacttt gatatatcct aaacgttgac cgttgacgat
    22321 ggcattttcc atgcttcgtc cgaaaacagc gattttacga ccagttgcca cagcggcatc
    22381 tgctgcttgc tgcaaacgga agatgttaga agcaaagctg gcaaaaatga tacgtccttc
    22441 gatttttgaa aagatcttca aaatagaatg cccaatcgtt ttttctgatt tagtaaatgt
    22501 tggaatctca gcatttgtac tatcagataa aaggcacaag actccttctt ccccgatacg
    22561 agccatttta tgcaagtttg ctggttcgcc aacaggagtg aaatcgaatt tgaagtctcc
    22621 agtcgctacg atatttccag aaggtgtttt caccacgatc cctaatgcat ctgggatact
    22681 atgggtcgtt ctgaaaaagc tgacagaagt ctttctaaaa cggatgatcg tatcttcatt
    22741 gatctcatgg agctctgcat ctcgaagcaa gccatgctca tctaatttgt ttgtgatcaa
    22801 cgctaatgcg agaggaccag catagatagg aatatttgct tgtttcagca agtagggtat
    22861 tccgccgatg tggtcttcgt gcccgtgagt aatcaccaag gcttttactt tgtgtaagtt
    22921 ttgtatgatg tagctgtagt cgggaatgac atagtcaatt ccaagtaaat cgtcttccgg
    22981 gaatttgatc ccggcatcaa tcaaaatgat ttcatcttgg aattgtaccc catacgtatt
    23041 tttcccgatt tcacctaatc caccaatagc aaagacgcct gtctcgttat ttttgatgga
    23101 aagtttcata ttaaaactcc actaatgaga aatcagcatt ttctttttcg tactctagat
    23161 gacttccttc tagaagttga acgaattcaa tattgtatgg ggtattttct tccacacgtt
    23221 ggcgagcgtc tacatcgctt tttgcctcaa tgtaaagaga ttttgtttct tcccgtttag
    23281 ggttgcgtac ttttgtttct tgataataaa ctttatagat cattgttttg tctcctttat
    23341 ctgcgtaaag cagtgattta gctagttgat ttttttagac aacacaaaac gaggggacaa
    23401 gccacctggt ttttcatatg ctttgactag aatactggat tcgagtcaaa gagacaagcc
    23461 tcgtttttgc ttatctgttc ggatattttt tcaaccgtac cttctgtata aaaaatatac
    23521 aacaattaat tgttattcta gcataaaaca gcaaataagt atagaaatca actagattga
    23581 aagaaaaaat caatgtttat catcccgcta taatcataat gactttttta tgagagaagt
    23641 gttctattaa taggctcgtt gtgctatcat ttttagtaat gaaaatgtaa caaaagatta
    23701 aaaggagatg agaaagtgaa actaatgtgg cattatacca tgcgttataa gaaattcttg
    23761 tttttcaatt tcatatgcgt atttggtttt attttgattg aattaggact tcctacgatt
    23821 ttagcacgta tgatcgatgt aggaatccgc aatgatgatt ttgattatgt gaagcaacaa
    23881 gggatattta tgatcgttat tactgtaatc ggtattattt tgaatatctt gttaggttat
    23941 tttggttcga ggattacgac taatatcgta gcagatattc gagatgattt gttcgaaaag
    24001 atccaaagtt attcgcatca ggaatacgaa aatctaggcg tatcttcatt gatcactcgt
    24061 acaacaaacg atgcttatca gatcatgttg ttcctgcaaa atattttacg tatcggtttt
    24121 atggcaccaa tgatgttcat tgtcagtttg tacatggtca tgcgtacaag tgtgacactc
    24181 agtttgtatg tagtaggtgc attaccttta ctattattgg cagtcgtagc gattgctaag
    24241 gtgtctgaac cgttatctaa aaagcaacaa aaaaacttag ataaaatcaa cagtatcttg
    24301 cgggaaaatc tttcaggatt gcgtgtgatt cgtgcattcg tcaatgaaaa gtttgaagaa
    24361 aaacgttttg ctgtagtcaa tgagaattat gcttctagtt caaaaagctt attccgtttg
    24421 atggctgttg cacaaccggg tttttatttc ttatttaata tcgtaatggt attgatcatc
    24481 tggagcgggg cagtgcaaat cgatgcaggc gagcttcgtg taggagattt gattgcgttt
    24541 atcgagtata tattccatgc cttgttctca ttcatgttat ttgctagtgt gttcatgatg
    24601 tatccaagag cagctgtttc agctggacgt atccaagaag ccctagatgc caaaccttcg
    24661 attgtagaag atccaaatgg tatatctgat acaaaaacta aagggtatat cgaatttcaa
    24721 aatgtaacat ttgcttatcc aggccattcg caagagccag tgatacgaaa tgtcagtttt
    24781 acagcctctc caggagagac cgttgctttt attggaagta ccggtagcgg aaaatctacg
    24841 ttgatccaat tgatccctcg cttttatgat gtgagtgaag gaaagatctt gatcgatgga
    24901 gtagacgtga gagattatcg gctaagcaag ttgcgagata agattgggtt tattccgcaa
    24961 aaagcgctgc tatttactgg aacgattgca gataatttgc gatacgggaa agaagatgct
    25021 acgcaagaag aaatggaacg tgcagctgag attgctcaag cttcagaatt catttctcga
    25081 aaaccagatg gatttaatga acatttatca gaaggtggtt ccaatttttc aggtggacaa
    25141 aaacaacgat tggcaatagc cagagccatc atacgccgtc cggaaatcta tatttttgat
    25201 gacagctttt ctgcattaga ttatcaaacg gatgcgaagt tacgtgctcg tctgaaaaaa
    25261 gaaacgacag aatctactgt attgatcgta gcacaacgtg tgggaacgat catgcatgca
    25321 gataagatca tcgtattaaa tgaaggagaa gtcgtcggta tggggacgca tcgggagttg
    25381 ttggaaaaat gcccgattta ttatgatatt gccgcttctc aattatcaaa ggaggaatta
    25441 gcatgaaaaa aaccttttct tccttaaaac gtttagctcg atatatcaga ccgtatcgtg
    25501 agacttttct tttagtgatc ctatttacag ttctgacagt ggctttcaac gtggctttgc
    25561 catatgttac aggacttcct actacagaaa tcagccgtaa tattgccaat ggcgaatcaa
    25621 tcaatttttc ttatatattc aaatgtctca tttggatcac agttgttgga atagggtatt
    25681 gtatttcgca attactttct ggtgttttga tgacaaatgt cgttcaaagt gccatgcatg
    25741 atttgagaag agacatagaa gaaaaaatca atcgtcttcc ggtttcatat ttcgataaaa
    25801 accagcaagg aaatattttg tctcgtgtga cgaatgatgt agatgcagtc agcggtgctt
    25861 tacaacaagc ttttattggt atcgtaaatg cgatattggg aattacgttg gctgcagcaa
    25921 tgatgtttta tatccagccg atgatggcgc tgatctctat gatcatgatt ccaacatcga
    25981 tctggatctc aaaacgagtg atcaatgctt cgcagaaata ttttcaaagc atgcagaatt
    26041 ctcttggtga gctaaacggc tacgtccaag aaaatatgac aggttttagt gtattgaaag
    26101 tatatggacg cgaaaaagaa acattggaag gattcaaaaa agttaatcac agcttgaaat
    26161 actttgggtt tcgtgcagca ttcatttctg gcttgatgat gcctctagtt caattaactg
    26221 cctatgctac ttatattggt atggctgttc taggaagctt ttatgttatt actggggcga
    26281 tcgttgtcgg tcaactacaa gcattcatcc aatatatttg gcaaatcagt cagccaatgg
    26341 ggaacgtgac acaattgtct tcagttttgc aaagtgcatc agcggcaacg aaacgtgtat
    26401 tcgagatttt agatgagcca gaagaaaaag aaaacaaagt agatgcttca ctgccagaaa
    26461 cgattttagg agatgtgaca ttcgatcatg tcgattttgc atatgatccg aagaaaccat
    26521 taatccaaga tttgaatttt gaagtgaaag ctggtcaaac cgtagctgtg gtcggtccga
    26581 ccggtgccgg caagacgaca ttgatcaatc tattgatgcg tttttatgac gtagacaaag
    26641 gagcaataag gattgatgga atcgacacca aatcaatgag tcgcagtgat gtgcgttcgc
    26701 tatttggtat ggtcttgcaa gatgcatggc tttatcaagg aacgattgca gataatatcc
    26761 gcttcggaaa gcttgatgcg acagattatg aagtagttga tgctgcgaaa acagcaaacg
    26821 tagatcattt tatccgaacg atgccagatg gatatgatat ggccatcaat tctgagggag
    26881 acaatgtgtc tttaggacaa aaacagttgc tgacgattgc ccgagcagtg gtctccgatc
    26941 ctaaaatctt gattttagat gaagcaacaa gttcagtaga cacccgttta gaagcgttga
    27001 ttcaaaaagc aatggatcgc gtgatggagg gacggacaag tttcgtcatc gctcaccgtt
    27061 tatcgacaat ccgtgatgca gatctgattc tagtgatgga tcaaggtcag atcattgaaa
    27121 aaggaacgca tgagagttta ttggcacaag gtggatttta tgaaaaactg tataacagcc
    27181 aatttgctga ggaagcagaa taagtcatat aagaataaaa cagtttaaaa cttatttttt
    27241 gttctctatt cttgataatg gtaaagtaaa gttatcaaga aaagtgagga cacggagatg
    27301 gaacagtttt taaatgaaaa aattactgaa gccaaaagag aagttgatcg tttaacgcac
    27361 gtctgtcaga cgaagccttt tgattcagct gatttttttg aaaatgagtt tcaaatcgaa
    27421 cgcttggcag cacaaataga agtgtacgaa ttaattttaa aaaaagtaat agaagaaaat
    27481 atagatgtac aataaaaaca ggtaaaacgt cagttaccag atactgtaaa tagacatctg
    27541 gcctgagcag gttttacctg ttttttttct tatgaaataa atatatgcta tgataccttt
    27601 attcaatagg attagtttct acaaaaaatg aaaggagaaa aataaatatg gaacggttta
    27661 tagcatcaaa tgccacagtg attggtgatg tgacattgtc agaagatgtg acgatctggt
    27721 atcaagctgt tttacgcggg gacagtaatt ggataaaaat aggacaaaga acgaatatcc
    27781 aagatggtac aatcatccat gtcgatcatg atgcacctgt agatattgcg gagaatgtga
    27841 cggtaggaca tcagtgcatg ctacatggct gtacaatcga aaaaggggcg ctgatcggga
    27901 tggggaccac gatattgaat catgcggtta ttggtgagaa tagtttgatt ggtgctggat
    27961 cattagtaac agaaggaaaa gttattcctc ctaatgtctt ggcttttggt cgcccagcta
    28021 aagtgatccg tcctttgaca aaagaagaaa tacaaaaaaa caaagaaaac atccagcatt
    28081 atgtcgagat aggtcggatg catgcgcaag gaaaattcaa ggagcaaaga taggcagtag
    28141 catccataaa ataaaaaagg atggtcagtt tgagttgacc atcctttttt atttggttta
    28201 gataagagag cttaaaaaag cttcctttga aacagattaa tttaatgaag aactgttttc
    28261 catgacttca tcgatcaatc catatgcttt tgcttgttca gctgtcatat agttgtcacg
    28321 atctgtatct ttttcaatca cttcaagcgg ttgtccagtg cgttcagcta aaattttgtt
    28381 taagcgttcg cgtgtttgca aaatatggcg tgccgcaatt tcgatttcag ttgcttgccc
    28441 ttgagcgccg ccaagaggtt gatggatcat gatctcagca tttggtaaag caaatcgttt
    28501 accttttgta ccagctgtca gcaagaagct tcccattgaa gcagccatac ccataacaat
    28561 tgtttggaca tctgctttga caaagttcat tgtgtcgtaa atagccatac ctgctgtaac
    28621 tgaaccacca ggagaattga tataaagata gatatctttt tcagaatctt gagcgtctaa
    28681 gaaaagcaat tgggcgatga tcgaattagc aagatcatct gttacttggc cgcttaacat
    28741 gatgatacgg tctttcaata aacgtgagta gatatcgtaa gctctttcac ctcgtgaaga
    28801 ttgttcaatg actgtaggaa ttaaattcat aatagagttc ctccttgatt tcgtttagaa
    28861 atagtgtacc ataatttagt ttctaatacc taaaatgtag tatacatttt tggtcaaaaa
    28921 aggtcaaata aaaaacttag gcaaattagt cgcataaacc cgctttatgg tatgataagc
    28981 agagaaacaa aacaaggagg aacaacagat tgatagttgg tattactggc cttatcggag
    29041 tgctgacagg tgctgtagtt gtctatatcg gcatgatact gcaaatgcgt cacttggaaa
    29101 ataaagaaca gcgtagacgt gaattggaat tgaaagtcaa agaaatcgag acgctgaatc
    29161 aattaaataa aaagatcaac gagatcttgc aaaaacggac aacgctgatg gaagaatatg
    29221 tcagctttga tgcatttgat gattgttata tcacgattga cgattttgcg tatctccaat
    29281 cattttcagc gcaaaatagt ttttatctgc caaattatat tttagacgag ctatttaaga
    29341 atatctccca tcgaaaagtg attttatctc cagatgaaac aatgaagatt ggtggatatg
    29401 cttataaagg cggacgcgtg attttagaga attttacgga tagtctgact gaaatgatca
    29461 atgaaaaaaa agctcagttg aagactatga cgcgccagcc gattggtttc ttctcgaaag
    29521 atgatgtttg gagctgatat tttgaagcat tgccgttgca catgagagcg tggtaatgct
    29581 ttcttttttt cttaatgata caatagaact gaacggagtg aagaaagatg ttacaaatct
    29641 atgcccatcg cggaagcagc ggcacccacc cagaaaatac gcttcctgca tttgcagaag
    29701 ctgtacgagt aggtgcagat ggtatcgaac tagatgtcca tctaagcaaa gatggttatt
    29761 tgatcgttat gcacgacgaa gaagtggacc ggacgactaa cggtaaaggg ctgattcgag
    29821 aaaaaacatt ggaagaactc aaaaaattga atgcaggggg caaattcagc aaagaatttc
    29881 cagcagctaa agttcctgaa ttgagagaag tgttaggact gctcctccaa aaaaattacc
    29941 gagggatgct aatgattgaa attaaaactg atcagtatga atatcccggt atcgaagaaa
    30001 aattagccga aacattaaaa agtagagatt ggccttttca acatgcatat tgcagctttc
    30061 atttggattc tttggaaaaa atcgcattac tggaaccgga gatacagctg gacttattga
    30121 tgagtacttc tgataaaaag atccaactag cagcagaaac cccttatata gaaggagtac
    30181 atccaaaaaa tacttggttg ttcgaacatc cagtccaggc agctgatttt ccaaaagcaa
    30241 ttcgtgcatg gacgattaac gatgaagaag aaatggccaa atgtcaagaa ctcaaaatag
    30301 atggaataat aactgatttt ccggagaaag ctcttcggtg gaaacaatca acgaaaagta
    30361 ggtaaaatat ggaaaaagta ttagtgatcg tcggtccgac agcagtcggt aaaacagcgc
    30421 taagtgtgga actcgcacaa ctatttggag gagagatcat cagtggtgat tcattgcaaa
    30481 tctataaaaa tctggatatc ggtacagcaa aaatcaaaga agaagagatg aataatgttc
    30541 cgcatcattt gattgatgtg atcgaaccta ctcaacgtta ctcagccgct gattttcagc
    30601 attcaggtcg acaattgatt accgagattg cgaaccgagg gcacctacct atcatagctg
    30661 gtggtacggg tctctatatc caatcccttc tatatgatta tcagttagga gcgacagaag
    30721 aagcgaatcc tgagattaga aaaaagtatg aaacgttagc tgaaacaatt ggttcccaag
    30781 cattatggaa tcagttgaaa gaaaaagacc cggcagctgc tgagaaaatc cactggaaca
    30841 atcaacgcaa agtgataaga gctctggaag ttttagagac gacaggacat agtatcacgg
    30901 cacctaaaga agagccaaag caattgtatg attacctcat gattggatta gatacgaagc
    30961 gtagtattct ttatgaacga atcaatcaaa gagtcgattt gatgctagca gaaggtttag
    31021 tagcagaagc gcgtaaggtg tatgagcttg gagaagtcca ggccagtcaa ggtattggat
    31081 ataaagaatt tttcccttat tttgaaggga aagaaacatt ggaagaagca acagaacaag
    31141 tcaaactaca ttcgagaaga tacgcgaaac gtcagttgac gtggtttcgt aaccgtttgg
    31201 atgcacagtg gtttgatctt ataagtgagc caaatcaaaa aagtcagatt gagcaaacaa
    31261 tcaaaaaatg gctggaggcg gaataaaatg gaagaaaaag tgatcatcgt aggggtagaa
    31321 accgaagcaa accagcgtta cttttcagag tcaatggaag agctagttca gctgacgaat
    31381 accgcatcag gagaagtcgt attcacaatt acacaaaaga gaccacaagt ggatcggcaa
    31441 acgattatcg gtaaagggaa attacaagaa ttagttcaac aagcggatgc gcatgaagcg
    31501 gatttgatca tctttaatca tgagctaact ccgagacaga gccaactgat taccgatgct
    31561 gttggtcttc cggtaattga tcgcgtgcag cttatcttag atatttttgc gatgcgtgct
    31621 cgttcgaaag aagggaagct gcaggttgaa cttgctcagt tagaatacct gctgcctcgt
    31681 ttagtagggc aagggaaaac attatctcgt cttggcggtg ggatcggaac aagagggcca
    31741 ggtgaaacaa agttagaaac agaccgccga catatacgga ataaaatttt tgctgttaag
    31801 aaagaattga aagaagtaga agctcatcga gagcgcaatc gccaaaaaag aaaaaatagc
    31861 gagatttttc agattggact tattggctac acgaatgccg ggaagtcaac tatcttgaat
    31921 ctattgacac aagcggatac ttattcgaaa gatcaattgt ttgcaacgtt agatccattg
    31981 actaagagat ggcgttttgc tgaaggattt gagattactg taacggatac cgtcgggttc
    32041 atccaagacc tgcctacgca actgatcgat gctttccatt ctacattaga agaaagtcaa
    32101 aatatggatc ttttgctaca tgtagtcgat gctagttctc cagatcgtat tttacaggag
    32161 cagactgtct taaaattgat ggatgaactg aatatgaaag aaatgccgat actgactgtt
    32221 tacaataagg cagaccagat cgacccagcg atgttcacgc ctacgctatt cccaaatgta
    32281 ttgatttcta ctcagacgaa agaaggtaag atggcgttga tcgaagcaat caaacgtcag
    32341 ctgatggaac taatgacccc ttatacactt tctgtgccaa gcaacgaagg acagaaatta
    32401 agcgagttga gaagacaaac aatggttttg gacgaagcgt acatggaaga aacaaacgaa
    32461 tatgaagtta aagggtttgc aaaaaccaat tcaaaatggt taagaaaaaa ccaataaaat
    32521 tttatttttt taa
//
LOCUS       DADVXE010000027        32269 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.027, whole genome shotgun sequence.
ACCESSION   DADVXE010000027 DADVXE010000000
VERSION     DADVXE010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.027"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(73..1014)
                     /gene="ribF"
                     /locus_tag="KB913_001362"
     CDS             complement(73..1014)
                     /gene="ribF"
                     /locus_tag="KB913_001362"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBB6819732.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(1018..1941)
                     /gene="truB"
                     /locus_tag="KB913_001363"
     CDS             complement(1018..1941)
                     /gene="truB"
                     /locus_tag="KB913_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBB6819733.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(2309..4671)
                     /locus_tag="KB913_001364"
                     /pseudo
     CDS             complement(2309..4671)
                     /locus_tag="KB913_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            5119..5292
                     /locus_tag="KB913_001365"
     CDS             5119..5292
                     /locus_tag="KB913_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6819734.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(5449..5796)
                     /gene="rbfA"
                     /locus_tag="KB913_001366"
     CDS             complement(5449..5796)
                     /gene="rbfA"
                     /locus_tag="KB913_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBB6819735.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(5823..8129)
                     /gene="infB"
                     /locus_tag="KB913_001367"
     CDS             complement(5823..8129)
                     /gene="infB"
                     /locus_tag="KB913_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBB6819736.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(8142..8453)
                     /locus_tag="KB913_001368"
     CDS             complement(8142..8453)
                     /locus_tag="KB913_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBB6819737.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(8450..8743)
                     /locus_tag="KB913_001369"
     CDS             complement(8450..8743)
                     /locus_tag="KB913_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBB6819738.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(8765..9940)
                     /gene="nusA"
                     /locus_tag="KB913_001370"
     CDS             complement(8765..9940)
                     /gene="nusA"
                     /locus_tag="KB913_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBB6819739.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(9963..10436)
                     /gene="rimP"
                     /locus_tag="KB913_001371"
     CDS             complement(9963..10436)
                     /gene="rimP"
                     /locus_tag="KB913_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBB6819740.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(10581..14939)
                     /locus_tag="KB913_001372"
     CDS             complement(10581..14939)
                     /locus_tag="KB913_001372"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBB6819741.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(15151..16860)
                     /locus_tag="KB913_001373"
     CDS             complement(15151..16860)
                     /locus_tag="KB913_001373"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBB6819742.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(16928..18196)
                     /gene="rseP"
                     /locus_tag="KB913_001374"
     CDS             complement(16928..18196)
                     /gene="rseP"
                     /locus_tag="KB913_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBB6819743.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(18357..19157)
                     /locus_tag="KB913_001375"
     CDS             complement(18357..19157)
                     /locus_tag="KB913_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBB6819744.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(19154..19966)
                     /locus_tag="KB913_001376"
     CDS             complement(19154..19966)
                     /locus_tag="KB913_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBB6819745.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(20161..20718)
                     /gene="frr"
                     /locus_tag="KB913_001377"
     CDS             complement(20161..20718)
                     /gene="frr"
                     /locus_tag="KB913_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBB6819746.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(20721..21443)
                     /locus_tag="KB913_001378"
     CDS             complement(20721..21443)
                     /locus_tag="KB913_001378"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBB6819747.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(21579..22460)
                     /locus_tag="KB913_001379"
     CDS             complement(21579..22460)
                     /locus_tag="KB913_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBB6819748.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(22559..23341)
                     /gene="rpsB"
                     /locus_tag="KB913_001380"
     CDS             complement(22559..23341)
                     /gene="rpsB"
                     /locus_tag="KB913_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBB6819749.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            23700..24179
                     /locus_tag="KB913_001381"
     CDS             23700..24179
                     /locus_tag="KB913_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBB6819750.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            24396..25487
                     /gene="phnW"
                     /locus_tag="KB913_001382"
     CDS             24396..25487
                     /gene="phnW"
                     /locus_tag="KB913_001382"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBB6819751.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            25480..25608
                     /locus_tag="KB913_001383"
     CDS             25480..25608
                     /locus_tag="KB913_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBB6819752.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            25612..26157
                     /locus_tag="KB913_001384"
     CDS             25612..26157
                     /locus_tag="KB913_001384"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBB6819753.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(26611..28302)
                     /locus_tag="KB913_001385"
     CDS             complement(26611..28302)
                     /locus_tag="KB913_001385"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBB6819754.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(28722..29669)
                     /gene="arcC"
                     /locus_tag="KB913_001386"
     CDS             complement(28722..29669)
                     /gene="arcC"
                     /locus_tag="KB913_001386"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBB6819755.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(29784..30803)
                     /gene="argF"
                     /locus_tag="KB913_001387"
     CDS             complement(29784..30803)
                     /gene="argF"
                     /locus_tag="KB913_001387"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBB6819756.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(30894..32123)
                     /gene="arcA"
                     /locus_tag="KB913_001388"
     CDS             complement(30894..32123)
                     /gene="arcA"
                     /locus_tag="KB913_001388"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBB6819757.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         8599 a         6927 c         5728 g        11015 t
ORIGIN      
        1 ctgggcttat ttatcaccca ttttattgta attgctagtt atacataaac aagagatttt
       61 atgcataatg ttttattgct gagaaaaata ttcagctgtt gcttgttcat cctccttgag
      121 ttgttcaatc aattcctcta cactagaaaa tttcacttga tctcttaaaa attgattcca
      181 gcgtaccgcg acatgttcac catagatatc ttgattaaag tccaaaatat acaactctac
      241 agtcagctcc cgtccttcac cgaatgtatc attatgtcca attgaaccca tggctggata
      301 ccatgtttcc ccaattttta tttccgacac ataaacacct tctttaggca aatgaaccgt
      361 gctctttact ttgacatttg ctgtagggaa tcctagtagt ctgcctcgtg catcgccatg
      421 gacaactacc ccttctacct catatgtgca acctaatagt tttgctgctt cttttacttg
      481 tccgctgtct agtaatccac gaatacgggt agagctgatt ttttcacctt gttcttcttc
      541 tttagaaact gtgacgattt tgaatcttcc tttggcatat tcaggaaaat gagcgacatc
      601 tgcaatgtct tttggtccat acgtataatc aaaaccggaa acagcatatt ttgcatgtaa
      661 ccctacgatg tattgatcaa caaattcctg cggtgctaaa tgagcaaaag aagaagtaaa
      721 atcaacttca tataaataat ctatacccaa agcggccatt ttttcttctt tttgcttaag
      781 gctagtcaaa tatttcacgc tgctaggatc gatcttttta aagacaatag atggatgctg
      841 attgaaagtc atcaatgcta atttcaatcc ttctttttgt gcaatttcca tacctgtctt
      901 tatgactttc tggtgtccga tatgcacgcc gtcgaaaaat cccagcacta aaacgacatc
      961 gtcttctgga atttgttctg attggtaagg atgtctgatc ttgatgatat tcattcgtta
     1021 ttcctcattt ctcaatactt tactaggttt taatttgttt ttttctttcg ggtttggctg
     1081 ataaatactg acaacttttc ctttataaaa caaagcaatt tcttctgacg gcatttctgg
     1141 gagcgcaaat acagtataat caagtctcat accgtttttt actttctgcc atacttcatc
     1201 agtaatatct actcgtttga accgttccac tcctttttct attggcagca aacaatcatc
     1261 gattgtccca tttttcacag cttgagctac ttcttctaat gtcagagcat ccttctggga
     1321 cataccggca cttgctgttc gggtcagatc agacatgtgc gcagggtaac caagtttctt
     1381 gcctgtatct acagctaatg tgcggacata ggttcctttc ccgcattcta cttcgaagcg
     1441 ccaagaaatg gttcctgtca cttcgtctct tgtcaattca cttgtccgga taaaacggta
     1501 aatctgagcc tttctaacag gacgctccac tgtttcatta ttgcgggcat attcatataa
     1561 ccgcttaccg ttgactttta ccgctgagta cattggtggt atctgggtga tctcaccaat
     1621 aaatgaagcc atcacttcat ctattttttt ttcagataaa gacatatcta ctggttttgt
     1681 ttctacccgt tctccggatc gatcttccgt cgttgtactg aaacctagag ttatctcgcc
     1741 tacatagatt ttcccagaat ctgtcaaata ttcgataact tttgtggctt ttccaataca
     1801 aatgggcaac acaccgtcta cgtctgggtc aagcgtaccc ccatgtccga tttttttcgt
     1861 atgtaagatt tttcttaatt tgaatacgca atcatgactt gtcattccgc gttctttcca
     1921 taaaggtaat aacccgtcca tgtcttttct ccatttcatt tttgatttaa ctgaattatt
     1981 ataacacatt gcatcaatta ctgacgaatt tgacatcata atgaacggtt tttatttttc
     2041 ggcaataaaa acgtaacaaa attcatgctc acgtaaatag aaatcatgtt atgctttttt
     2101 aaaggaggga atagaatgga agattttttc tttgcaccat ttgattggat ttatgggtgg
     2161 cttacaggta aatagtttgg ttttcacttc ccaaaaacga aaaaaaagac tggccattct
     2221 tccagtcttt tttccgtttt ttttatttat tttttcagtt tcttaatcaa tgtaaaaaat
     2281 tctattttgc gggatcgatt ttatcatttt attggtcaag atttttccat ttccaatcca
     2341 atacttctgg cagatcaata ccattttcac gaatatagtt ttgatgttct tgtaatttct
     2401 gatccatttt tttcgcaaaa tcttctgctt gacttccttt gatttttaaa gctgcgtctt
     2461 ttgccaaatg ataacgatca agttcattta ctacacgcat gtcaaatggt gtcgtgatat
     2521 ctccattttc tttgtagcca tgaatcatta aatgatggtt atgacgatca aagaaaatcg
     2581 tgcggaccaa tgtttcataa ccgtggaaag caaataagat cggtttgtct tttgtaaaat
     2641 attgatcaaa ttcttcatcg ctcaacccac gcggatcttg acttggatga cgtaatttca
     2701 ataaatctac gacattgatg aaccgaattt ttagttttgg gaattcttcc agcagcaaag
     2761 ttacagctgc taatgcttct aagttagatt ccgttcctgc agcagcaatg accaattcag
     2821 gttcctcctc ttttgctgtc gaagcccaat caatgatttt caagccttca ttcactaaga
     2881 cggctgcttc ttctgctgag taaaattgag cacgcggatg tttggaagag atgatcaaat
     2941 tgattttttc tgacgagcgg aatgctttat ccatgactgc gagcaatgta tttgcatccg
     3001 caggcagata ttcacggatg aactccgcct tcttttctgc caaatgtgtc aatattcctg
     3061 gatcttggtg gctatatcca ttgtgatctt gctggaagac tgttgagctt gcaatgagat
     3121 ttagcgaagg ataatcattt cgccaagaaa ggtcatgtga tttccgcatc catttgaagt
     3181 gctgagtcaa catagagtca accactcgca agaatgattc gtaacttgca aaaaaccatg
     3241 ccgtccagtc agaacgtacc cttctaagaa cccttcatct tggtgttccg ataattgact
     3301 gtcgatgacg cgaccagatg gcgaaagcca ttcatcattt tctggttcga ttttttccat
     3361 ccattggcga tttgtcgttt tgaaaacttg attcaatcgg tttgattttg tttcatctgg
     3421 tccaaatata cggaaatttt ctggattttt ctcaatgatc tcgcgaacga atttaccaag
     3481 ttcggtcata tcttctgctt taacggagcc tggtttttca aattgcaaag tatatttttt
     3541 ccaatctggc ataataagcg gtcttggatc gattccacca ttggtgatag gattttttgc
     3601 cattctttgg tcaccagtag gcgcgatttc tctgatttct tctaaaatac gtccttgtgc
     3661 atcaaataat ttttctggtt cataggattt cagccaacgg agtaaagcat ctgcatgatc
     3721 catatgttct tgatctacag gaatcggtac ttggtgtgct cggaaggttc cttcaattgg
     3781 ttccccgtcc cattcttttg gaccggtcca tccttttggt gtgcgtacga tcaatactgg
     3841 ccattttggc atcacgacat ctgttgctgt cttcaggcga gcttcttttt ggatggattt
     3901 aattttctcg attgcttgat ccattttttc agccataaca ggatttaatt tttctgaatc
     3961 atttccttca ataaagaaag gttcccagcc aagtccgtta aagtaatttg ctaattctcc
     4021 atctgattta cgtgccaaga tcgttgggtt ggctattttt gcaccattta aatgaaggat
     4081 cggtaaaaca gctccatcta tcactggatt gataaagaca tttgagaacc agcttccagc
     4141 taaaggaccg gtttctgctt caccatcacc aatcacgaca gcagagatta cttcaggatt
     4201 gtctaataca gctccgactg catgtgaaag agagtatcca agctctccgc cttcatggat
     4261 agaacctggt gtttctggtg ctgcatgaga agcaatgcct ccaggaaatg aaaatcgttt
     4321 gaataatttt tgcattcctg tctcatcttc cgttacttct ggatagatct ctgtgtaact
     4381 tccatctaaa taagcattcg ataccatgac ttgtccgccg tgtcctggcc cttcaatata
     4441 aaacatgttc aaatcatatt tattgatgac tcggttcaaa tggacataaa taaaattttg
     4501 gccaggaatc gttccccaat gaccgattgg atgttttttg acatcttcgg gtttcagtgt
     4561 acgtctcagt aaggggttat ctttaagata aagttgccca acagaaagat aattagcagc
     4621 acgccaccaa gccgtcattt tatcaaagta ttctttacta gaataatcca tacataacac
     4681 tccttttcat tattactctt attctagcgc agatactccc aattgaaacc taataagcac
     4741 ttctgttcat ttgtttggat tttatatcta gccaaatgaa caggtataaa aaaccacgaa
     4801 atttttcctt tcgctgacgt tttttacatt gatccaaaaa acttgtcgtt atcacaatgg
     4861 ctgttccgca gttcatttcg ctcctcatca tgcataattt gctgaatgac gctgggccag
     4921 ttaacacatt gctggaaaac tggggctgga tcgagcaatt cctttcctga ttgatccgtt
     4981 ttatgtaaaa gtctctgtta tctttgtcaa tatgtgaatt ggtatcccag ctactatgct
     5041 aatttctaca gggattatcc aaaatttgga tcgtgaccaa atcgaagcgg cgtaatcgga
     5101 aatatcaata acttcaacgt gatttttctt ttaactgtca acggaccgac aaactcaaac
     5161 ttttatggtg caggttccac tgatcttcta gttacttggc tatacctgac tgtcactaaa
     5221 atagattaca atctagcttc cgttatcggt atcttgatct ttatctatat gcaaaaattt
     5281 atatactact agaaaaaaga aagtcgaatt ttttactttt ctttttctct tttttggtta
     5341 gctgacacgc cgcaagacta aagtcatgga actcttaggt aatacgtctt aatgaaaaca
     5401 aaaaaatccc gcaacccctg atttcacagg atttgcggga gtttttgatt agtctttgtt
     5461 caagtcgcga agcaattcat cgatatggtt gccatagaca actgattcat caagttcaaa
     5521 gaacaattca ggtgtcttat aaatacttag attgtgccct aactctcgac gaatcaatcc
     5581 tgatgcttta ttcaatccat cttgtgctgt tttcttatct gatgctaagt cagataaaat
     5641 gctgtaatag atcgttgctt gctgtaagtc ccccgtaact ttcacatctg tgatcgttac
     5701 gttctccaca cgagggtcac ggaccttttt gcgcaaaata tcattgactt cttttaagat
     5761 ttcttgaccg actcggcggt cacggtagtt agccataatg attggcctcc ttttatcagt
     5821 ttttagtcat ttttgacttc ttccatgata aatccttcaa ttacgtcatc tactttgatg
     5881 tcattgaatt tttcaatcat tgcaccacat tcataaccca ttttgacttc tttcacgtca
     5941 tctttgaatc gtttcagact tgcaagttgg ccttcataga ttacgattcc gtcacggatt
     6001 acacggacac cgctatctct acgaatatat ccttctgtta cataggcacc tgcaatcgta
     6061 ccaactttag aaactttgaa ggtttcacga acgatcattt gaccggtgat tttttcttca
     6121 aattcagggt ctagcatccc tttcatcgca gtttcgattt cttcgatggc tttatagatg
     6181 atacggtgaa gacgaatatc gacttcttca gtatcagctt gcacttttgc ctgcggtgta
     6241 ggacgaacgt tgaaaccgat gataatagcg ttgctggctg ctgctaaggt tacatcactt
     6301 tcattgattg ctccgacagc tgaatggacg atttttacac ggacaccttc cacatcaatc
     6361 ttcttcaatg atgcagccag tgcttctgct gaaccttgta catctgcttt gatgattacg
     6421 ttaacttctt tcaattcgcc ttctttcagg ctttcaaata agttatccaa agtcacacgg
     6481 cttgtggcag cacggttttc taataatgca cgtttcgcgc gttcttcacc cgctgcacgt
     6541 gctgtctttt cgtcttcgaa gactacgaaa cggtcacctg cttgaggtac atcattcaag
     6601 ccagtgattt ctactggcgt tgcaggtcct gcttctttat cgcgacggcc aagatcgttt
     6661 gtcattacac ggacacgtcc gtaagtatta ccgacaacga ttgggtcacc aacatgaagt
     6721 gttccttctt ggacaagtaa ggttgacaca ggacctttac ctttatcaag acgtgcttcg
     6781 atcactgttc cgattgcgcg ttgtgttgga tctgctttta aatcttctac ttctgcgact
     6841 aacaggatca tttccagcaa ttcttcgatg ttttggccga atttcgctga gatctcaaca
     6901 aagatcgttt ctccacccca tgcttcagga attaactcat actcacttaa ttcttgcata
     6961 acatgttgag ggtttgcacc tggtttatca attttattta cagcgacgat gattggaacg
     7021 cctgcagctt tggcatggtt gattgcttca actgtttgtg gcatgacgcc atcatctgca
     7081 gcaacaacta agatcgtgat atctgtgata cttgctccac gtgcacgcat acttgtaaag
     7141 gccgcatgtc ctggtgtatc caagaaagtg attggtttac catcaatatc gatctggtag
     7201 gcaccgatat gctgtgtgat tccgccggct tcgccgcttg ttacacgtga atggcgtaat
     7261 gtatccaata aagttgtttt cccatggtct acgtgtccca taatcgttac gactggcgga
     7321 cgtgagacta atttatctgg atcgacttct tctgcctcga agaatttatc gatatcagca
     7381 atgtcaactt ggactttttc ttgtggttcc atgccatagt ccgtcgctaa cagttcaatc
     7441 gtatctttat ccagtgcttg gttttgattg accatgacac caagcataaa taatttttta
     7501 atgatttctg ctggctcacg atgaattttt ttcgcaatat ctgctacgtt cataccttca
     7561 gtatactcta atacatctgg caattcacgg aatttgcgtg gtggtacagc tggtttagtt
     7621 gattgttgct gtttgccttt tttacctttt ttattataac gattacggtt attattatta
     7681 aatttgccgc gattgttatt gtttggtttg ttgttattgt tagtacggtt ttgattgccg
     7741 ccttggctcg ttccttgacg attttggctg ctggtatttc ccgtattatt ttggtttgtt
     7801 gttggttttt ttccttgatt cacttgaccg ctcccttgac cgcgatcttg ataactgcgg
     7861 ttatttttat ttttttgttg attgttcgtt gtttcttttt tacgttgatc gttcggctgt
     7921 tgattggctg gttttctgct tgcttgttgt gcagcttgtt gtttcgtgct tgggtttttg
     7981 aacgcttgtt gcaatttctt ctcatcattg ctagtaatcg cacccatatg gtttttcaca
     8041 tcgatgccaa gttgttgtgc tttttccacg acgtctttac tagatttttt gagttctttt
     8101 gctaattcat agattctttt gttgcccatg caatcacctt cctaaccttc aattagctcc
     8161 ttggtcttct tcgcaaatcc ggcatccatt attccgaata ccttgcgagg ttttccgatc
     8221 atctgcgtga tttctgcttc agaaaatagc tcaaagcaag gaacttcata atatgaactc
     8281 ttatctttta tcttttttct tgtattctcg cttgcatcgg ttgccacaaa caccaatttt
     8341 gctttttgtt tgcggatttc agcaatggtc agttcttcac ccgtgattag ttttcccgcg
     8401 cgcatcgcta gaccgatgag attcatggct ttttgccgat taactgtatt cattttccaa
     8461 ataactcttt acgtgctttt tggtgagtga catagtcaag aagttcttga taaaactcat
     8521 ctgttaatgt tgtttcgagt actcgatcga gaattttttt atcccaagct tgttgtactt
     8581 cttccggctc aagtgagaca tacgctcctc gtccaggcat ttttccagtt ggatcgatcg
     8641 atacttcccc ttcttttgaa cgggtgattc ggaccatctc ttttttaggt ttcatttcac
     8701 ctgaaaccac ggatttgcgt aaaggaattt tcctttgttt catctctttg cctccttact
     8761 aaagttaagc ttctggtttt tcttcgaccg tttcattgtt gaatgcaatt gtttcatatt
     8821 catcgtctgt taaatctgac tgaacgattg cttcatcatg cagttcttct gtttcttttt
     8881 gttgttcttg attttcataa aattccgtca tgtcagattc tgatttgata tcgattttat
     8941 ggttagtcaa tttagcagct aaacgtgcgt tttgtccgcg tttaccgatt gctagcgata
     9001 attggtagtc tggaacgaca actgtgcagg cctttggatt tgtctcatcg aagatcacat
     9061 ccatgacttg tgcaggattc aatgcatttg caatgaatac agctggatct tcattccatt
     9121 cgacgatatc catgttttcg ccttttaatt cattgacgat tgcttgaact cgttgtccct
     9181 ttggcccgac acatgtaccg actgcatcga tatttggatc atttgagcga actgccactt
     9241 ttgaacgatc gccagcttca cgggcgatgc tgacaatttc aacgattcca tcatagactt
     9301 ctggtacttc ttgctcaaat aagcggcgca ataggtctgg atggctgcgg ctaacaaata
     9361 cttgcggacc tttagacgta ttttctactc gggaaacata aactttgatt cgatcatgtg
     9421 gttgataaaa ttcatttggc atttgatctt gtttagaaag aactgcctca attttaccaa
     9481 gattgacata aatataacgt ttatcctggc gttcgacgat tccttgcatg atgtcttttt
     9541 cataagcact gaattcgtta taaataatcg ttctttctgc ttcacgtaca cgctgtaaaa
     9601 taacttgttt agccgtttgc gcagcgatcc gcccaaaatc ttttggtgtt acttcaaaac
     9661 ggatcgtatc accgatctca tatgctggat tgattaaaag tgcatctttc aatgagactt
     9721 ccaactgtga atccatcact tcttccgtta cttcttttac cgcatagaca tggatctttc
     9781 cttttttctg atcaaattcc acttcgacgt tttgtgcttg gccatagtga cgtttgtatg
     9841 cagaaaccaa tgctgcttct aaagcatcga tcacgatttc ttttgagatc cctttttcag
     9901 cttctaaagc gtctaacgca tttaacattt ctttactcat tttttctgat tcctctccgt
     9961 gattaaaatt ggatagctaa gcgagctttt gcaatatttt ttcggtcaaa agtcaattct
    10021 ttttctcgtg tttttatgcg tattttcaat gtaagctgtt cagcatcaaa tgattgaaga
    10081 aatccttcat attgtttttc gccatctact ggttggtata aggagacatg gacataatca
    10141 ccaagtgcct tttcatagtc gctttctttt ttcaatggcc gctctgctcc cggggaggat
    10201 acctccagga aataagcttg aggaatcgga tctggatctg ctgcatcaag tttttcactc
    10261 agtttctcac tgacaaaggc gcattcttcg atatcgatac cgccttcttt gtcaataaat
    10321 actcgtaaga accagctttt tccttctttt acaaattcga cttcgacaag ttcaaaattt
    10381 tgttcatcta aaatcggtgt caccatttct gtgactgttt caacgacgct actcaaaagt
    10441 ttcgcctcct taaaaaatta agtgcgtaat tccattaaaa agagtgagcg aaaaatccgc
    10501 tcactcacag ttagtatcat tacctataag aactatacca tactctgctt aaaattacaa
    10561 gcagacagga aaacagatgc ttatagcata tcgaataacg ataattgatt ttcatctggt
    10621 agatctttca atacgccatt gtcgttcata tattcgatca atgtttttga aactttaccg
    10681 cgggtggcaa gatcttcttt ggataaaaat ggaccgtctt ttcttgcttc aacgatttgt
    10741 tttgccacgt tggttcccaa acttgggaca gctctaaatg gtgcgatcaa cgtatcacct
    10801 tcaataacaa agttaacggc atccgattta tacaaatcaa tcattccaaa tttgaatcct
    10861 cgttccagca tttcattggc taactccagc actgtcagtt gattcttttc ttttacggaa
    10921 gcatctaatc ctttgtccgt gatttctttc attgcttgtt tcacagcatc ttttcctttg
    10981 cacatggaga ctagatcaaa gtcgtctgca cgtacagaaa agtatgcaca gtaatacaaa
    11041 atagggaaat aaaccttgaa ataagcgaca cgaagagcca tcaatacgta agctgcagca
    11101 tgggctttcg gaaacatata tttgattttt gaacaagaat cgatatacca gtcgggcaca
    11161 ttattttctt tcatcgccga tagataggtt tctcgcaatt catcagggat cttgttccat
    11221 tgtcctttac gaacagtttc catgatttta aatgccatcc cgctatctaa tccagcatgg
    11281 atcaaataaa ccataatatc atcacgacag ccgattactt ccgccagtgt cgcatctcct
    11341 cgtcgaatca attcttccgc atttcctaac catacgtctg taccatgaga tagtccggaa
    11401 atttgcagta gttctgcaaa agttgtagga tgcgtttctt ctagcatccc tcgaacaaaa
    11461 cgagtgccga attctggaat acctaatgtc cctgttttgg aataaatttg ttcctgactt
    11521 actccaagta cttcaggacc ggcaaatatc cgcatcactt ccgggtcatc cgtagggatc
    11581 gtttgtggat cgatccctga taaatcttga agcatccgaa taacagttgg gtcatcatgc
    11641 cctagaatat ctaatttcaa tacattatcg tgaatcgagt gaaaatcaaa atgagtcgtt
    11701 ttccattccg aattttgatc gtctgctgga tattggatcg gcgtaaaatc atagacatcc
    11761 atataatcgg gaataacgat gatcccccct ggatgctggc cggttgtccg tttgactcca
    11821 gtagcgcctt ttgctaatct gtcgacttct gcacttcgaa actgcagatt attgtccctt
    11881 tcgtatcctt ttacatagcc atatgctgtt ttgtcggcga ctgtaccaat cgttccggca
    11941 cggtaaacat agtcttcgcc aaacaatact ttcgtatagt tatgggcttc tgcttgataa
    12001 tcacctgaga agttcaaatc aatatcgggc actttgtctc catggaatcc taaaaatgtc
    12061 tcaaatggaa tatcatgacc gtctttgttt aagcgtgcac cacattttgg acattgtttt
    12121 tctggcatgt caaatccaga accatacgta ccatcttcaa aaaactcgga atattggcac
    12181 tctggacaat aataatgagg ggctaacgga ttaacttcag tgattcctgt catcgtcgca
    12241 acaaagctag agccaacaga gccacgtgaa cctactagat agccatcttc attactttta
    12301 tgcactagtt tttgggcgat cagataaata accgagaagc cattaccatt aatagaattc
    12361 aactcttttt ttaatcgttt ttgaatgatc tcaggtaacg gatctccgta catttgtttt
    12421 gcttttgtgt aactcaattc tgatatttca tcttctgaac ctggaatctt cggtgtataa
    12481 agttcatctt tgactggaat cacttcttcg cagatatctg cgattttatt cgtattttct
    12541 actacgatct ctttcgctgt ttcttcccct aaaaagtgaa atgcagttag catctcatcg
    12601 gttgttcgga aatggacatc cggcaaacta tgacgattca acggattcgc tccgcccata
    12661 gaattgatca aaatttttcg gtaaatggca tcttcttcgt tcagataatg tacattacct
    12721 gttgcaacaa cgattttatc caaacttttt ccgatttcta ccaaattttg gataatttct
    12781 tccaaatcat gttcattttt taccaattct tgctcgatca aaggcgcata gaccgctttt
    12841 ggcataactt caatataatc gtagaatttt gctcggtttc ttgcctcttc tacccctttt
    12901 tgcatcatgg cttcgaatat ttctccctta tcacaagctg agccgatcaa tagattttca
    12961 cgcatctttt tcaattggga gcgtggtatt cgtgggacgc gttcgaagta ttcgacattc
    13021 gacattgaaa tcagtttgaa caaatctttc agtcctgcct gattttttgc taaaatcgtt
    13081 acatggaaag gtcgagccct tttgtaagaa tctccttctc cgatatgctc atttagctga
    13141 tcatgataaa gcatgttatg attgtccatt gcctctttca caaagatcca tgctaagtga
    13201 ccagttgctt cagcatcata gattgctcgg tgatgctgtt ccaagctgac accaaatttt
    13261 ttagataaca cacctaatcc gaaacgtttg aattgaggat acagatatct agctaattcc
    13321 aacgtatcaa tgactggatt ggccgcttca ggaataccat accttgcgta gctagtattc
    13381 aagaacccca tatcaaaagc cgcgttgtgg gctaccaaaa ttgtatcttt tgaaaattca
    13441 aggaacatcc gcaatacttc ttcttccgac tttgatcctc gaaccattcc atccgtgata
    13501 ccagtcagat ctaccgttgt tcgtgacaaa ggatgtcctg gatcgataaa ttcatcaaag
    13561 ctttcgatca catttccttt atacattttg actgcggcta gctcgatgat cgtgtcatat
    13621 actgcagaca atcctgtcgt ttccacgtca aatacgacat atgtggcttc actcaatgct
    13681 tcatgtgcat cattataagc aattgggaca ccatcatcta cgacattcgc ttccacgccg
    13741 tataagattt tcacacctgc tttttttcca gcactatgtg cttccggaaa ggcttgcgca
    13801 ccaccgtggt ctgtaatggc gatagctcgg tgtccccatt tccctgcttg tgccacaaga
    13861 tcagagatgc tgtttgttgc atccatcgta ctcatattgc tatgaacatg aagctctact
    13921 cgtttttccc cttcaggagc ataatctttg cgaggtgtat gtttgacttc tatgatatct
    13981 tgcgcattca tgaccaaatc acggacaaac gtatcttctt gaatacttcc tcgtaccttt
    14041 aaccagctac cgacactgat cgcatcaaat acttgttcat ctttttcgcc gttcgagaat
    14101 tttttgacga taaatgatga agtataatct gtgattttca aagtcaagat cttgcgtttt
    14161 gaacgtagtt ctctgacttc tttgtcgaat acgtacccct caagtgtgac tcttcgttct
    14221 tcttcaacga tactgatcat tggtgtcgtt ggttcatcgg ctggaatatt tcgtcctagc
    14281 tggatgtgga tgggtccttc aagagctggc gattgctctt ttctttcctt tttcttttgt
    14341 tcgtggacaa ctagactttc agctgcttgc ttcataaagg cttctgcctg ttcttgtttg
    14401 cgttcttcaa aaagtttcaa tactcgttcc gcttgctgct catccacttc tggttcgata
    14461 cgaaattttg ggaatccgta actgacgaac aactcttcta ctaatggcaa gtattgttgc
    14521 ttcaaataag aaatagctcc tgtactgtcg attggcaaga tgactttacg atcttttatc
    14581 acaggtacct gcgttttcaa tacttgctgt gctagtggtg tatcgcattg ctgattttcc
    14641 aaagcttggg cccagtaatc ttgcaagagc tgttcatcga atgtctggtc atctgctaag
    14701 atattcagtt tgacttgtgc aatatcttta aaagcgatag tcagatgctg agtcaatgac
    14761 cgatatagca taataggcaa aattttggaa aaatgcagcg taaattccca taaacgcgat
    14821 ttacgatgga ccactacact atccatttca ccagcagtaa gcagtggatg atttttttct
    14881 gcttcctcta gttggatttg ttccaacagt ttttcaaata aatctcgttt ttctgacaaa
    14941 gatatacgcc ctttctgatg agaaacaatg caattgatcg catcttatcc tcttcttttt
    15001 cagtaccttt tagtatactc gttttttctg agttttacat taaaaaattg gaactgcgat
    15061 tcaaatcgca gttccaattt taaaagcgaa tcatcagatt gtcaaaaaca gctgattcag
    15121 ctatttttat tttctgtgtt ttaacgctta ttattcgcct tggttcaaga ggattggtaa
    15181 agtattcacc aattcttctt tacgtacttc aaccatttcg ccagttttct tgattttcac
    15241 ttctacgatt ccatccactg cttttttacc gacagtgatt ctgattggac agccaatcaa
    15301 atcagaatcc gcgaatttca ctcctgcgcg ttcatttctg tcatcaacca gtacttcata
    15361 gccagctttt gtcatcgctt cttctagttc attcgtcagg tttgtttggt attcgtcttt
    15421 tagattcatt tggacgatat gcaaatcaaa tggcgcaatt ccttttggcc agttgattcc
    15481 ttgttcatct gaatgttgtt ctacgattgc tgataataaa cgacttacac cgataccata
    15541 acagcccata atcacaaatt tttctcgtcc attttcgtct agtacagttg ctcccataga
    15601 ttcactgtaa cgagtgccga ttttgaagat atgtccgatt tcgattcctc gagtaaaggc
    15661 aagaacacca ttgttgtctg gtgaaggatc tccttcttgt acaaaacgaa gatcttcata
    15721 agaaagtaca gtgaaatcgc gttctggatt cacattttta tagtggaatc ctgtttcgtt
    15781 cgctccagta atggcattcg ctaaatcttg gacataacgg tctgcatata cttttacgtc
    15841 atctgaaaca ccgactggtc cgacagaacc aaactcagca cctagatatt tttgtgcttc
    15901 ttcttctgtt gcttcttcta aaaagtcagc agataaaaag tttttcagtt ttacgtcatt
    15961 gacttcatgg tctccgcgta ccaaaacaag gacaggttgt tcatccgcaa tgaacaatac
    16021 agacttgatg attttttgag gttcaacaga aaagaaatct gctacttcgt caattgattt
    16081 tacgttaggt gtagctactt tctccaattc aagctgtgtt tcatgcgatt tttttgatac
    16141 atagtagctt gtagccatct ccaagtttgc agcataatca ctttcagtcg aataacagat
    16201 cgtatcctcc ccgatttctg agatcgccat gaattctttt gagtctttcc cgcccattgc
    16261 gccaccgtct ccgataatcg agcgaaattc taagccacaa cgcttgaata cttcggtgta
    16321 ggctttttcg taatctttat atgtctcgtc caaactttct tccgttgcat ggaaagaata
    16381 cgcatctttc atgataaact ctcttccgcg aagcaaaccg aagcgaggtc gtttttcgtc
    16441 acgatattta ggttggattt gataaagatt taaaggtaat ttcttatatg aattgatttc
    16501 attacgcatc aaatcagtaa aagtttcttc gtgagttggt ccaaggatca tttttcgatc
    16561 attgcggtct ttgaaacgat acaagtttgg tccatatgtt tcgtaacgcc cggattcttc
    16621 ccaaagttct gctggcaaga tggcaggcat cagcatttct accgctccga ttttttcaaa
    16681 ttcttcccgc ataatgcgtt tcagtttttc caatacacga tttgctaatg gcagatatga
    16741 ataaataccc gctgatactt ggcggatata tccagctctt agcaagattt gatggcttaa
    16801 tacttctgca tcatttggaa cttcgcgtaa tgttggaatc aacatttttg attgtctcat
    16861 tctatatact cctttatttc ctcaaaatag ttatcgtttg ttattatacc ctatttgtca
    16921 actttttcta gaaaaagaat cgttgaatat cgttccatgt aactagcacc atcaacaaca
    16981 ttaaaaatcc aaagccagct aatgtcaata ttccttcttt ttcttgactt aatggtttcc
    17041 cgcgaatccc ttcaaaaata ttcaagacta atttcccgcc atctaaggca ggaatcggaa
    17101 gcagattgac gattccgaga ttcattgaaa gaagcgccat caaactaata acagttgtta
    17161 caccttgatt tgctgcttct gaagacaatt ggtacatcat gacaggtccg cctaatttat
    17221 ctaaactgaa acctgtaaat agtgatccta aggctttgaa aatttccaat gaaccgctga
    17281 aagcttgacg cgtccctcca atgatcttat ccataaaacc tgtattcatt ggggctttta
    17341 taccaagttg gccaactttt tcgccatttg actctacaga tttcggtgtc acgtcgacag
    17401 attgcacctg accttctcgt tcgatcttaa agtctaatgt tttatccgga tttttcgtaa
    17461 tgactgttgt cagatcattc catgaatgga tttcttttcc gtccacactg actacctcat
    17521 cattttcttt taagcctgct tctgccgcag ctccattagg catgatctct cctacgcgat
    17581 tagtgttcgt cacttgaaca ccaccttgca taaatgccag aatgatgaat aacaggattg
    17641 ccaaaataaa gttattcatg ggtccagcaa agttggtcag catacgctgc cacaatttag
    17701 ccgattggaa ctgtacgtct tttggcgcaa ttctgatttc tgttccgtcg ttttcaataa
    17761 tcgtcgcatc gtgatcaaca gggtaggtta ctacttctgt ttcgtctcca ttcacataac
    17821 cagtgatagt cagctcatct tctaaatcat aacggctcaa ttccatcggg atagcatttg
    17881 tcaattggat tttcttactt aaatttatct tctctacgat gccgtcagaa tttagtaaaa
    17941 gagaaagagg cattcctggt gccatttctg tttcatcatc cccattgcct gccattcgaa
    18001 cataaccgcc aataggtaat aggcgaagcg tatatgttgt cccgtctttt gcttgatgcc
    18061 cataaatttt cggacccata ccgatagcaa attcgcgaac gaggattcct gatcgtttcg
    18121 caaagaagaa atgaccaaac tcatgaacaa tcactaatat accaaaaacg atgataaatg
    18181 tcagaatcgt tttcatagct tttttctcct ttacttgttt tttgtgtttt ttataaaaca
    18241 acgataaaac actataattt taccatagta taccaaagac accaatagta tcaatataat
    18301 gaaaaataaa aacctgcgtc ttttatgaaa ttcacaaaga aacgcaggta tacttactaa
    18361 ataatgccaa ataaatgcat gataggaaat acaaacagca aactgtcgaa acggtctaag
    18421 attccaccat ggcctggtaa gatatttccc gagtctttca catcataatg acgtttgatt
    18481 gcagattcga ccaaatcacc aaattgtccg actgctgaaa aaataatcgt catcagaagc
    18541 atgacaaaca taccatgatt aaatagttct tttgctgggt atagcaataa ataaagaaat
    18601 gcgactacaa cagcactacc aataccaccg agcgcacctt caatcgtttt gttgggcgaa
    18661 atatcaggac ttaacttatg ctgaccataa cgtcgaccaa ccatatatgc tccgatatca
    18721 gttgcccaaa caataaatag accaaatatc aaaacagcca agctttctgt tcgtgcattg
    18781 acaaaattct ggaaacctat tcccacatac aagctgacaa gcacaggaaa acctgcttca
    18841 tcaatcgtat acgtattttt agaaataact gatgttccta aaagaatcat aactataaga
    18901 taaaataaca taaatgtact tacattctct ggaagaaaga aaaaccatct ttcttttggc
    18961 aaaacaagta acactgcacc aacggcggat aaaactcctt caaaacttaa gagtgtcaat
    19021 cctttcatcc gaaacagctc gtaaactcct attactgcta agattgctgc tgtaagctca
    19081 accgctatgc ctccgatcca tataatcgga ataaacaaga ctagcgccac ggctgctgtg
    19141 accacacgtt gtttcatgac tgatcccctt tctcatcttc tgtttttttt acaccgccga
    19201 atcgacggtc tcgattttga taagaggcga ttgcttcttc aagatgcgca ccatcaaaat
    19261 caggccaaag cgcttttgta aaatacagct cactatatgc gatctgccat aacagaaaat
    19321 tactaattcg ctcttctcca cttgtacgga tcatcagctc aggatcttgt aactctttag
    19381 gcaagaaacc tgtcattaaa tgcttagcaa tcaattcatc atcgatttct tctgcgtgta
    19441 tttctccttt tgctacttct tcggcaattt cttggacagc agtcacgatc tctgctctgc
    19501 ttccataatt caaagcaaaa ttcaatacca ttccagtatt gttttttgtt tgctcaattg
    19561 cacgtcttac agcatcttgc gtatgttctg gcaatacgtt ttcataaccc atgacatgaa
    19621 ctttgacatt ttctttaatc aattctggta cgaacgtatc aaagaagtcg acaggtagtt
    19681 gcatgagaaa acttacttca tcttttggtc gcttccagtt ttcagtcgaa aaggcataaa
    19741 gcgtcaacac tttcactcca agccttgatg ctttttttgt gactttcttt actgtttcca
    19801 tgccttcttt atggccagca actcgtggca aacgacggtt ttgcgcccaa cgaccattgc
    19861 cgtccatgat gatggcaatg tgctgaggaa ttggtccatc ggtattaaat tgaaattcgc
    19921 ttttttcttg aatatatttg tttttttgcg gaaaaaaacg taacattctt tttcctccta
    19981 tacttaaaag attcccacta tcttaagtat tatagcaata tctaactgtt tttcctatga
    20041 aatcattgtt tttttattta aaaactgaat aattttttct ttttttaatt tttaaataaa
    20101 agaaatataa ataaaaacag aggaagcgga atgatccgcc cctctgtttt tatgatttta
    20161 ttaaacttcc aataattctt tttctttatc agcagcgatc ttatctactt ctttgatgct
    20221 gttatctgtc aatgtttgta cgtctttttc taatccgcgc aaatcatctt cggtaatatc
    20281 accatttttt tgttgttttt tatattcatc gatcgcatca cgacggatgt tacgaatcgc
    20341 gatttttgca ttttctgctt cttttttaac atctttagct aattcttttc tgcgttcttc
    20401 tgtcagttgc gggataacta agcgaatgac atttccatca ttggttggac tgattccgat
    20461 atcacttgcc ataatagctt tttcaacatc ttgaagaatg ctcttgtcaa aaggtgtgat
    20521 cattaaaaca cgtgcttctg gaatttggat tgatgccatt tggttcaatg gtgttggcgc
    20581 accgtagtag ttcacagtaa tacggtccaa aaggctagcg ttcgcacggc ctgcgcggat
    20641 ttgcccaagt tcacgttgaa gattttgtgc tgcttttttc attttttctt ttgcttctgt
    20701 cataattgca tctgccattt ttatttcccc cttacagttg ttccgatatt ttcgcctaag
    20761 attgcacggc gaatatttcc gtgttcattt aaattgaaga caagcagtgg aatatcatta
    20821 tccatgctta gtgaacttgc agttgaatcc atgacttgta atcctttggc aataacttcc
    20881 agatgagtca gttcttcaaa ttttactgca tttgcatcta ctttcggatc agcagaataa
    20941 acaccgtcta cattgttttt agccatcagg ataacatctg cgccgatttc tgccgcgcgt
    21001 aatgctgctg ttgtgtctgt cgagaagtac gggttgccgg taccgcctgc aaagataacg
    21061 atccgtcctt tttctaaatg acgttctgct ttacggcgaa tatatggctc tgcgatttga
    21121 cgcatttcaa tcgaagtttg cacgcgtgtc ggtacaccca cgttttccaa cgtatcctgt
    21181 aaagctaagg cattcataac tgtagctaac atacccatgt aatcagcttg agcacgttcc
    21241 atgcccattt gtgctccgat ttgtccgcgc cagatatttc cgccgcccac aacgattgcc
    21301 atttcaacgc ccagctcgtg aacttctttg atttcttgga tgatttcttt gattactggt
    21361 ggtttgattc caaatcctgc gtccccagct aaagcttctc cactcaattt taagactaca
    21421 cgctgatatt tcggtgtgac catgttcatt cctccaatat tttctattgc cattttacca
    21481 tacttagatg atttcgacac tctaagactg gtttttcttg ttttgcttaa aaaaagggag
    21541 cgcacaaacc gtgcgttccc gtctgttatt caacagaatt attttttcac ttggctcata
    21601 acttcttcta caaagttatc ttcgcgtttt tcgatacctt cgccaacttc gaaacgtacg
    21661 aatgttttaa cagttgcgcc ttttgatgca acgtattttt caacagtcat atcaggatct
    21721 ttaacgaatg gttggtccac caaagcgatt tctgctttga atttcttcaa gcgtccttct
    21781 accatttttt caacgatatt cgctggtttg ccttcgttca atgcttgttc tgtaagaaca
    21841 gttttttcat gttctaattc agcttctgga atttgtgatt cgtttacata acgaggattg
    21901 atagctgcta cgtgcatagc tacgtctctt gcaactgttt cgtcagttgt tccatctaga
    21961 acagtcaata cggcaatacg tccgcccata tgcaagtatc caccaaatgc agcattgtcg
    22021 tctttttcta caacttcaaa gcgacggaag ctgatttttt ctccgataac ttgagttgct
    22081 tcgatcaagt cagattcaat tgtaccttta tctgttttga ttttcattgc agcttccatg
    22141 tctgctggtt tgttttcagc aacaagttct gcaatttctt ttactaaatc ttggaacatt
    22201 tcgtttttag aaacaaagtc tgtttctgag tttacttcaa cgattgctgc agtgttacct
    22261 ttcacagcaa ctgaagccaa tccttcagct gcaatgcggt catttttctt cgcagccttt
    22321 gccattcctt tttcacgtaa aagatcaact gctttttcca tgtcgccttc tacttcaact
    22381 aatgcttttt tcgcatccat cattcctacg ccagtcattt cgcgtagttc ttttaccatt
    22441 ttagctgtaa cgtctgccat gtttaactcc tcctgtgtgt ttttcttttt aaaaaaagct
    22501 gcttcaaagg agagtgaggc ttgtcgccca gcctttgaaa cagctccatc attcaaaatt
    22561 attctgctga agaattgtcg ccttcaacaa catctacgat ttcttcgatt gatgttgctg
    22621 tgttttcttc tgtgaaatct tcttcaacta cttgatcttc accttggttt ccttcgatga
    22681 aagcatcagc catttttgaa gtaatcaatt taacggcacg aattgcatcg tcgtttgaag
    22741 ggattactac gtcgatttca tctggatcgc agtttgtatc aaccatagct acgattggga
    22801 tatttaattt gtgtgcttct tgaacagcaa tacgttcttt acgtgggtca acgatgtaca
    22861 ttacatctgg gattcttggc atatcagcga taccgcctaa gaatttttca agacgttcac
    22921 gttctttgtt caaaccagca acttcttttt taggtagaac ttcaaaagtt ccatcttctt
    22981 ccattgcatt gatttgtttc aaacggctga tacgtttttg gatagtatcc cagtttgtca
    23041 atgttccgcc taaccaacga tggttaacga agtattgtcc tgcacgagtt gcttcttctt
    23101 tgattgcttc ttgtgcttgt ttttttgtac ctacgaataa tgctacgccg ccttcttcag
    23161 caacgctctt catgtaatca taagctgcat ctactaattt aactgttttt tgcaagtcaa
    23221 tgatgtagat tccgtttctt tctgtgaaga tatatttctt catttttgga ttccagcgac
    23281 gagtttggtg accaaagtgt acgccggctt ctagtaattg tttcatagaa attactgcca
    23341 tgtttgtttc ctccgatttg gttttatttt tcctcttctt atcttctacc ttgccggcaa
    23401 actttttcaa gcacctaccg acaatccaat aagaatgtgg atttgctgat gcataaagca
    23461 ccctcagcta ttatacagac aaaagatccg tatcgcaaga gcaaatatac ttttctgctc
    23521 aacattcaat agtttacctg aaagataaaa agaattcaag aaaaacagta gatttctctt
    23581 tgtttcttta ttatcctttt tccataaaat aattttaggt ataaaagacg aatattattg
    23641 ggcaatcctt cttttttttg ttatgataca tgtgaaatct ttcgtaaagg agaaagaaaa
    23701 tgcgcaaagc tcaaagacat ttgctgatta aacaagtcat tgaagaattc ccgatccgta
    23761 cgcaagaaga actattaaac aaacttgggc attatggcgt taccgccacg caggcaacga
    23821 tttctcgaga tatccgtgat ctaaaaatcg tgaaggcacc tgatgaaaat ggcgtttccc
    23881 gcttcgtatt gtttcgcgaa aaaggaactc ctgagactag gactgaggaa gaggatcggc
    23941 tggttcaaat gattgaagac attgtattga aagtcgaacg agtccacttt ttgacgatcg
    24001 tcaatacctt gccagacaat gctcatttat ttgcatctgt tttagatgag atcaaacctc
    24061 cctctattgt cagtacaatt gctggattcg atacgatcat ggtcatctcg gaaaatgagg
    24121 aggacgcaaa acgagtagaa gaatttcttc accatccaac tgaagtatca cttttttaat
    24181 cagagcacgt attcctaata tggaatgcgt gtttttttat tttcaatatt ttccttattg
    24241 aataaacctt tacactcttt acaaaaatac atcatttttt attcaaattt ttcaacacct
    24301 tgattgaatc acaataatca tcatttatat tggatgttaa caagagcagc ttcttgctct
    24361 ttgtgtattt caaaaaagaa atgaaaggaa atcatatgta taaattatta acttctggac
    24421 cattgacgac ttctgaaaca gtgaaaaatg ctatgctgat cgatcattgt acttgggatc
    24481 aagaatacaa agaaattaca caatggataa gaaaaaaatt attggatctt gctcaagtat
    24541 cggaaggaat atacacaacg gtcttaatgc aaggtagcag ctccttcggg gtagaatcgg
    24601 tattaagttc tgtgatcagg ccagaagata ctgtactgat ttgttcaaac ggcgcatata
    24661 gacaacgaat gatcaacatg tgcgaatgtc tgaaactgaa ctataccgtt tatgaggtat
    24721 cggaacatca aatcctccaa gctcatgtga ttacacagct gattgaagag aatccgtcta
    24781 tctccgcact agcaatggtc catagcgaga ctacttccgg tattttgaat aatttggaag
    24841 agattgctgc tgtcacacaa gaaagagatc ttttgtttat agtggacgcg atgtcaagct
    24901 ttggtgggat accgatttgt gtagccgaac tagggattga ttttttgatt tccagctcaa
    24961 acaaatgtat tcaaggtgtt ccaggctttt cttttgtact tgctaataaa gcggaactgg
    25021 aaaaacgaaa aaatgttagc cgaagtttgt cacttgatct atatgaccag taccgcgtga
    25081 tggaaaacga gaatggcaaa tggcgtttca cttcccctac ccatacggtt ttggcttttc
    25141 aacaagcgct gaaggaacta gaggcagaag gaggaatcga aactcgatat tcacgttatc
    25201 tcgccaataa tcatgtgcta cgacaaaaaa tgacagagat ggggttccag cctttcattc
    25261 aagaatatca ggggccattc atcacctctt ttctttaccc taaggactgg cgatttgatt
    25321 ttaatcattt ttatcagtat ttaaagcaaa atggatttgt gatctatccc gggaaaatca
    25381 gcgatcatga atgttttcgt atcggaaata ttggcgagat ctatccggaa gatattttgg
    25441 aactgacagc aattatcaaa gactataagg agaacgttaa tgattaaaac tgtaattttt
    25501 gattgggcag gaacaactgt ggactttggc tgtatggctc ctgtccacgc ttttagaaat
    25561 gcttttctag aaaaaggaat ccaactgact gacaaagaaa tccgctaacc gatgggaaaa
    25621 ttaaaatggg atcatatcca acagcttctt tccctccctt ctgtcaaaaa acaatggata
    25681 gctatttatg gacaactacc tcaggaaaaa gaggtggagg aattgtatca acaatttgaa
    25741 cattatctgt ttaaagattt ggtcaagcat tctaccttga aacccgacac attggaaacg
    25801 atcgaacggt tgagaaacgc tgggatcaat attggttcca cgaatggatt taatgctcct
    25861 atgatgacaa tcgtagcaga aaccgcaaaa aaagaaaggt attcaccaga cttcatggca
    25921 acttttgaag acgtcgaagg gtatggtcga ccgtttcctt atatgatcca taaaaacatg
    25981 cagtacttca aaaacaagtc ggttgatgaa gtaatcaaag tcggagatac ggtctcagat
    26041 atccaggaag ggaaaaatgc cggagtgttg acagtaggtg taattgaagg tagttcgcta
    26101 atggggattt cttatgatga gtaccaaaaa ttagagatgg ggaaaaagat cgtttaaaac
    26161 agtctgttgc tcttagattc caacaagccg gcgctgatat ttgtgtaaac aatttaaaag
    26221 agttaacaga atacattttg tacgctgaca tgaatccaga atgactttta tacaaaataa
    26281 gaggttgtga aaaagctgtc ctgtatcaag taataaaaac agccaagcaa aaatagctcc
    26341 tcatattttt cgtttggtta ggcttattac cgcagatgca agcttttgaa caccgtttat
    26401 tcgaaaaaaa aaagggagct gtgacacgac ttttgtcaca gtccccttat ttgcaaacaa
    26461 acagtgttta agagacaacc tctccactaa acggtgttca ttcagctgac tctcggtatt
    26521 tgctcaaaaa acgataaaat ttgaaaagct attttctctt ttgtttctct aatactcgga
    26581 tcagaacgct gatttcacat tctctttttc ttacatctta tctggtgcat gaagtcctag
    26641 caaacgaagg tcttctttca ataatacagt cactgcataa actagagcta agcgtgcttc
    26701 tttttgttca tcatcagcta aaatcttcgt atgagcatag tatttgttga atgcttgtgc
    26761 taatttgatt gcatgtttcg caatcactga cggttcgtat ttttccccag cagacaagac
    26821 cgtttcaggg tatttttgaa ctaatttaac cacttcccag ctggtatcgt cattcaatgc
    26881 atagtctgct gtttctgaag ggacaaatcc tgctttttcc aacaggctga ctgcacgagc
    26941 atgtgtatat tgcacataag gtccagtttc tccttcaaat cgaacaactt cttccaggtt
    27001 aaagtcaaat gtattcagtc gatcgttttt caaatcgtgg aaaatgactg ccccaacccc
    27061 aacttgttta gctacagcat ctttgttttc caaatcaggg tttttctcgc tgatttgttc
    27121 tttagcagat tggattgctt catttaatac ttcttctaat aagacgatct ttcctttacg
    27181 agttgataat tttttaccac cttgcgtgat caaaccaaat ggaatatggt gcatgtcgtc
    27241 agaccagtca aagcccattt ccttcaagac agctttcaac tgtttaaaat gatagctttg
    27301 ttcattccct actacatata gagattgttt gaagtcgtaa gtacgtttac ggtacaatgc
    27361 agcagctaag tcacgtgtaa tgtatagtgt cgcaccgtct gacttcttaa tcaacgctgg
    27421 attcaggtca taagcagata ggtcaacgat ctctgcacct ttatcctcgt tcagcaaatg
    27481 tttttcttct aaaagtttga cgatttcatc catcttgtca ttgtagaaag cttcaccgtt
    27541 caacgaatcg aaacgtactt ccagcagatc atagatttta ttgaattctt tcatcgattc
    27601 atcacggaac cattgccata attgaatagc ctctttatcg ccttcttcca gacgtttgaa
    27661 ccaagcacga gcttcttcat ttaattctgg ttctgtttca gctacttcat ggaattggac
    27721 gtataaacga agcaattcat tgattggttc tgctttaaca gcttcttctg taccccattt
    27781 tttgtaagcg acgatcagtt ttccaaactg tgttccccag tcacctaaat ggttgatgcg
    27841 gattggctga taaccgattt tttccataat gaaaccgatc gaattaccga taactgtcga
    27901 acgcaaatgt cccattgaga ttggtttggc aatattagga gaagacatgt cgattggtac
    27961 tgttccttga ttcccgatgt tgctatcccc ataatgttct ttttctttca ctactgtttg
    28021 caaaactttt ttgctgataa gttctttatt catgaaaaag ttcaagtaag gtccgacaac
    28081 ttcgattttt tcaaagttgg cagaatcgat tttttctgct aaatctgcag cgatttgctg
    28141 tggcgctttt cggtaaactt ttgctaatga aaaggctgga aatgcaacat ctccgtgttc
    28201 agctgatttt ggattttcta gtaattgctc gacttgttcc agtgttaaat catctttgac
    28261 agcgtcatag acagcttttg cgacaagatc tttattattc atctttattc ctcctaaagt
    28321 gttcccttga ttgttaaaca aaaaaaatct ctagcgacgg catacttagt atgccatcac
    28381 tagagacgag atttcccgcg gtaccactcc aattgtccta aaaaaggacc agctccatct
    28441 gatatcggta gacgaccgtc tgtttaaaac agaattctcc aagtgcgctt cgttgtatct
    28501 tcttcattcg gcttccacca cttccgaatt cgctagccaa gaatgataca agtactctct
    28561 tgttcaacaa atcttagtct tattaaactt tcttgaatta tatcagaaaa aaaaacgaaa
    28621 ggctagtcgt ttcataaaaa aacaatccag atggcctaaa ggagaagaaa taccacctgg
    28681 atagctataa atcatttcgt aaatacgaaa gacttaacaa attaatcagc tacgataatc
    28741 gttccttctt cagaagctaa aagattctcg atattttcta aagaagtgat gattgcctta
    28801 gcgtttggtt ttgcttcaac aaatgcaata gctgcttcta ctttcggaag catgcttcct
    28861 ggagcgaatt gcttttcatc aatgtattgt ttcatttctg aaacagtaac agtttctaat
    28921 ttcttttgat ctggtttttg gtaattgaca tacacattgt ctactcctgt caatacgatc
    28981 agcaaatccg catcgatgat ttcggctaat ttttctgaag caaaatcttt atcgattacg
    29041 gcttctcgtc cttctaatcc agtagctgtt tctacaacag gaatcccacc gccaccaaca
    29101 gagactgtga taactccttg atcgaccagc gtttcgatga cacgtgcttc tttaatcgag
    29161 atgggtttag gggaagcgac tacttttctc catccacgtc cagcatcttc tttgaatgtc
    29221 acagtggagt cagcattcat ttgttctttg gcttcttctt ccgtgtagaa tggaccgact
    29281 ggtttacttg gatttttgaa tgaaggatca ttttcatcca caataacttg agtgactaaa
    29341 gaaaccacat ctttatcgat ccctttttcc ttcagtactt cgcccatggc gttttgtaac
    29401 cagtaaccga tagatccttc tgtcattgca acacatgtat ctaaaggcat tgccggtgtt
    29461 ttctcagaat cagcagcttg ctgctgaatc aataggttac cgacttgcgg accatttccg
    29521 tgggagatga tcaattcatc tccttgttcg ataaatttca ctaaatactt tgctgtttcc
    29581 attaacgctt cttgttgggc ttttgcactt gcatccgtag acaagatggc attgccccct
    29641 aaagcgacaa ctacttttcg tttggccatt tcattcgtcc tttcttcagt tctaccgaat
    29701 tttctagata acaaaacgag ccagcgtttt gtgattttcc ctcaatgctg actcgttttt
    29761 tcgtgagatg aatgtggtta tgcttaaacg cgagggataa acaagttacc taatgttgct
    29821 gccatgatcg ctttgattga gtgcatacga ttttctgctt ggtcaaattg acgagcatat
    29881 ttgctgcgga agacttcatc tgttacttcc atttcagtga tgccaaagcg ttctttcatt
    29941 tgttcaccgt aaacagtgtt tgtatcatgg aaagctggca agcagtgcaa gaagatcaaa
    30001 cgatctgtgt tgtgtgtttt ttctaccatt tccatattga tttggtaagg tttcaacaat
    30061 ttgatacgtt cttcgaattt atcttcttca cccattgata cccatacatc agaataaagg
    30121 acgtctgctc cgtctacacc tttatcaaca tcgtcggtaa tcatcaattg tgcaccggat
    30181 ttttcagcaa agccttctgc cattttgacg atttcttctt caggttgtaa ttcttttggt
    30241 gcaacgatac gcatattcgc tcctaaaatt gcacctgtga ctaataaaga gttagccata
    30301 ttgtttcgac catctccgca gtaagcaaca gtgatacctt ctactgttcc aaagttttct
    30361 tggatagtta aaaagtcagc gatcatttgt gttggatgcc attcatcagt caagccattc
    30421 caaactggaa caccagagaa ttctgctagt tcctctacca ttttttgact gaatccacgg
    30481 aattcgattc cgtcaaacat acgtcctagt actttagctg tatcttctgt ggattctttt
    30541 ttacctaatt ggatatcatt tgcacctaga tattcaggat gtgcacctag atcgatcgct
    30601 gcagtagtaa atgcagaacg agtacgtgta gatgtttttt caaataaaag cgcaatattt
    30661 tttccttcta gatagtgatg tgggatacca cgttttttca agtctttcaa gtgttctgaa
    30721 aaatcgatca aatattgtaa ttcttctttt gtaaagtctt tttctgctaa taagcttctt
    30781 ccttggaata ctgattcttt catattaaac attctccttt agattgtttt tatttaagat
    30841 taaagaggaa atcccgacgg cagctgacag taagactgcc gtcaggaaac aaattacttc
    30901 aagtcttcac ggacaagtgg ttggctcatg cagcgtggac caccacgacc tcgtgacaat
    30961 tcacttgaat tgatttctaa cactttgatg ccatagctac gaagcaattc gttcgataca
    31021 taatttcggt tataagtgac tacaacacct ggagcgattg ccaatgtgtt tgatccatca
    31081 ttccattgtt ctcgaggtgc aacgatctca tctccattac cagttgggat cagtacaaga
    31141 tcatctaatc caagagcagc tttcatcgtt tcgtgtaagt tatctgaatg agtaatcttg
    31201 atatcatcac catctggttc gattgtaaag acatccatct taccgtcttt actttgaatt
    31261 gctggatgga tagtgaattt atcgtgatct accattgtaa atacggtatc caaatgcatc
    31321 attgcacggt tgttcggaat tttgattgcc aacacttttt caaatcctga attttttgcg
    31381 aataggtggc gtgctaattt ttctaaagct ttcgcattag ttcgttgaga aatcccaaca
    31441 gctactactt tatcgcttaa gatcaattcg tctccgcctt cgatatgatc tggattttca
    31501 cgatccaacc atacttcgat tcctttattt gcaaatcttg gatgatgttt caaaatatat
    31561 tctgtaaaca tcgattcacg acgacgtgct tcaaaagtca tcttattgac tgtcatccca
    31621 tttcccattg atgcggaagg gtcgcgtgta aagtacaagt ttggcattgg gtccatgtaa
    31681 aatggatagt catcgtctgc tgacagatca tatagactgc tagaacgtac ttcgatatct
    31741 tttgtacgaa ccccagccat gattttatct accatttctt gcgtttccat tgatagaagg
    31801 aactcatgaa gaccctctct tacagcattc gatgcaatat gagattcatc caacatttta
    31861 ttcaagaatt gttctttgac attgcctgcg tcaatcgctt ctgccgctaa tttttccaag
    31921 taaagagtct cgacgccttc attttgcaat gtcttcgcaa agttgtcatg ttcttcttga
    31981 gcaatcggaa gatatggaat atcatcgaac aacagacgat ccataatatc tggtgtcaaa
    32041 ttttccactt cttgtccagg ccgtttcagt aaaactgtct ttaatttccc tatttcagag
    32101 aaaacgtgaa taggtttatc catgttgtgt tgcctccttc tttttgatta catgtatagg
    32161 atatcctcct tttgtaatca ctttcataat tttgtctcat tcaaaatgag acattcctca
    32221 cattaatatt cgataattaa ataattaaac gtttttctat ttttaagcg
//
LOCUS       DADVXE010000028        30603 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.028, whole genome shotgun sequence.
ACCESSION   DADVXE010000028 DADVXE010000000
VERSION     DADVXE010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.028"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..1031)
                     /locus_tag="KB913_001389"
     CDS             complement(<1..1031)
                     /locus_tag="KB913_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6819758.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="KB913_001390"
     CDS             complement(1113..1802)
                     /locus_tag="KB913_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6819759.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="KB913_001391"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="KB913_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBB6819760.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /locus_tag="KB913_001392"
     CDS             complement(2329..2832)
                     /locus_tag="KB913_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBB6819761.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3036..3163)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="KB913_001393"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="KB913_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBB6819762.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="KB913_001394"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="KB913_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBB6819763.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="KB913_001395"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="KB913_001395"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBB6819764.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="KB913_001396"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="KB913_001396"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBB6819765.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7463)
                     /locus_tag="KB913_001397"
     CDS             complement(6444..7463)
                     /locus_tag="KB913_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBB6819766.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7636..8541)
                     /locus_tag="KB913_001398"
     CDS             complement(7636..8541)
                     /locus_tag="KB913_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6819767.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="KB913_001399"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="KB913_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBB6819768.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="KB913_001400"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="KB913_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBB6819769.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="KB913_001401"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="KB913_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6819770.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /locus_tag="KB913_001402"
     CDS             9754..10398
                     /locus_tag="KB913_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6819771.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="KB913_001403"
     CDS             complement(10454..10957)
                     /locus_tag="KB913_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBB6819772.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11554..12519
                     /locus_tag="KB913_001404"
     CDS             11554..12519
                     /locus_tag="KB913_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBB6819773.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12618..13790)
                     /locus_tag="KB913_001405"
     CDS             complement(12618..13790)
                     /locus_tag="KB913_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6819774.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13777..14922)
                     /locus_tag="KB913_001406"
     CDS             complement(13777..14922)
                     /locus_tag="KB913_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6819775.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14936..15868)
                     /locus_tag="KB913_001407"
     CDS             complement(14936..15868)
                     /locus_tag="KB913_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6819776.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15985..17064
                     /locus_tag="KB913_001408"
     CDS             15985..17064
                     /locus_tag="KB913_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6819777.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17061..17679
                     /locus_tag="KB913_001409"
                     /pseudo
     CDS             17061..17679
                     /locus_tag="KB913_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(17789..18016)
                     /locus_tag="KB913_001410"
     CDS             complement(17789..18016)
                     /locus_tag="KB913_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6819778.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18119..20707)
                     /locus_tag="KB913_001411"
     CDS             complement(18119..20707)
                     /locus_tag="KB913_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBB6819779.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20727..21386)
                     /locus_tag="KB913_001412"
     CDS             complement(20727..21386)
                     /locus_tag="KB913_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6819780.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="KB913_001413"
     CDS             complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="KB913_001413"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBB6819781.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22159..23025)
                     /locus_tag="KB913_001414"
     CDS             complement(22159..23025)
                     /locus_tag="KB913_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6819782.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23134..23775
                     /locus_tag="KB913_001415"
     CDS             23134..23775
                     /locus_tag="KB913_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBB6819783.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="KB913_001416"
     CDS             complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="KB913_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBB6819784.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25216..26115)
                     /locus_tag="KB913_001417"
     CDS             complement(25216..26115)
                     /locus_tag="KB913_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6819785.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26117..26914)
                     /locus_tag="KB913_001418"
     CDS             complement(26117..26914)
                     /locus_tag="KB913_001418"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBB6819786.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26892..27596)
                     /locus_tag="KB913_001419"
     CDS             complement(26892..27596)
                     /locus_tag="KB913_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBB6819787.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27727..28302
                     /locus_tag="KB913_001420"
     CDS             27727..28302
                     /locus_tag="KB913_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBB6819788.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28420..29097
                     /locus_tag="KB913_001421"
     CDS             28420..29097
                     /locus_tag="KB913_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBB6819789.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(29187..30482)
                     /locus_tag="KB913_001422"
     CDS             complement(29187..30482)
                     /locus_tag="KB913_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6819790.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT         9020 a         6444 c         5529 g         9610 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctag ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc tttttcattt tcctagactt
    11401 ctgctataat aaccaagaat taattttgta acagattttt ttgaaaaaac aagtttcttt
    11461 cattcaaaaa atagaaaaag cttgctaatt attggttaac cagcaaacag gagtattaaa
    11521 atatcttgtt ttattgaata gcaggaggaa atcatgaaat tccattatca tatattgatc
    11581 aatccatcgg caggcagcgg aaatggctat aaagtagcag aaagaatttt accggtatta
    11641 aaaaataagc atattgacta tacacttcat tatagtgaat acaaaggaca cgatgctgag
    11701 attgctgaaa ctttggcaaa agaaacattg attccttgga tagaagaaga acagaaaaca
    11761 atcgatactt tccccctttt gatcatcgta ggaggtgacg gcaccttaca tcaggtactt
    11821 gatactttct atcagatgga agtagaattc ccagttgctt atattccagc aggttctgga
    11881 aatgattttg ctcgaggggc aggccttcca aaaaatccca aaaaaggact tcagctgatt
    11941 ttagcagctc aatcaccaga aaaagtccac ataatggctt atgaagaaaa aataagtgaa
    12001 aaaaaaggaa tagctgttaa taatttcggt ataggattag atgcagctat cgtccatgcg
    12061 acaaatcatt cttccacaaa aaagcgattg aacaaataca acttaggatc attttcgtat
    12121 ttattctcta ttctccgtgc tttattcact caaaaaggat ttccaattct ggtagatgca
    12181 ggaggaaaac aattaagttt ttcaaacgca tttttatgta cagcaacgaa gcatcctttt
    12241 tttggcggag gaatcgcgat tgttccaact gctgatgcgt ctaaaccagt cattgatttt
    12301 gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc tcattctttt acttatacag
    12361 aaaaaacaat tgaaatcgaa atatttccat cactacacaa caaacagatt acgtatcgtt
    12421 tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa tggaaaaacg accttttgat
    12481 atcacaataa ccacaactaa acagttgttt tggtgttaat aaaagaggtt ttgtcagaag
    12541 ctacatctgg aacaccgttt attcggaaaa aaggactgtg acacgacttt tgtcacagtc
    12601 ctttttttac tatgcagtta attctttgcc caattgggtt gccatcgata gtttctttct
    12661 ttacccaaaa taaattggat cattgaaaac accgcagcaa aagcaactaa gacacaacca
    12721 ttgaaccaaa aagattctgc aaatgtttga ttgtaactga gtgtttcact gatcaagtta
    12781 ttattttgaa caaaccaata tgttggtgtg aatgccgcta ttttgctaac catttctggc
    12841 aagtattctg ctggtacaaa caccccaccg ataaagcaac tgcctgtgat aaaaatatct
    12901 ttgatcccac cgctggtttc tgagtttttt accaatgaag tgatacaagc cgaaaagcta
    12961 atgatcggca ataaaaacaa gaaagtattt aaaatatgat accataccgt tatatcccac
    13021 gaggtgtgga tcactaacag aaccattaga agtaagaagc cactgaacaa cagcagcgag
    13081 taactaatca aactaaaggt tactttgcga ttcaagtttc gtttggtaat gggcgcactc
    13141 tggtttcgtt tactgatctc tttgcgatta aacgctagat tgatgacgct gaaaccgcta
    13201 aaaatggata gaaacaaccc ataagacaag aaattaaagg ttgtgcccgt caacagcttt
    13261 ttcatccgct gactatatcc cgcacttagc tcaacttctc cagtaaccga gagtgccatt
    13321 tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt cttgaaacag aatcagtgtt
    13381 tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag aaaaggcatc tgggcgactc
    13441 tgtatcttga tcgtcgccat ctttcctact tcgacttgtt cggtaaagtc tgcaggcaga
    13501 tgtaagataa tgtttacacg attaaaataa agagcatcat cgatttcttt ttgtgaggtt
    13561 ccatccaatg taacgactgt ttccttgtca ttcaaatatt tacgaaggcc atcgactaca
    13621 ggcgactctt cttcactaat caaggcgatt ttcgcatctt gcagagaggt attttcaaca
    13681 tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga taattacacc tatcagtaaa
    13741 ttcgatttat ttgctttaag caatgtccaa atcgttttat aaagcgtcat aacgcacccc
    13801 tctttccatc caagcatttc ctaacgcaaa aaggaaaata aatccgatca accatagaag
    13861 attggtataa aaactagcca aatcagtgta gaaataaagt ttatacaaac tttcgctgat
    13921 caagttgacg agatttaatt gaccaacaat cggaatatga agatcaatcc aatacttcac
    13981 ttgttccgac cccatcatac cagcaaaaaa gctcatcgca atcgtcactg aaatcaagat
    14041 gctatccttt tgcaccagat tcatttttgg tatcaaatta ccaaccaatg tacctaacaa
    14101 aatcgcacac aacgacccca gagcggtaac aatcatcaac cattgccaac gttcaccaaa
    14161 gtctacttga tagataaaac gaaagacagc taacataata taaatctctg tcaaaacaat
    14221 cgtaaagctt gctgccaaat tagcgattga aactaacgat tgctttctag gaatcaagga
    14281 caagcgaata ccatttgacg attgatttgc ttgctgatcc tgtacattgc ggacccccca
    14341 catcgtcccg tagagaatcg ccattccaat cagagtgaag aaataaaaac ttttgaaact
    14401 catattacga cctgcatgaa cttcttgaaa agatacttct tgttcaaaaa cagtcatgat
    14461 gggcgcgaga tcaacgttct ccacttctgc cactttactc gaaattatac caatacgctg
    14521 taaaaattga tccatgacgt ttttcatcaa cgtctgactc attcctgctt gacccacatg
    14581 gagcgaaaca gatgaaccat caatgagata aaaaccagcc aaatcatctg catttagctt
    14641 ttcattcgct tctacttccg atagttcctg tacttcaaat aatggtttat cattgacttc
    14701 gacttgttct aagactgtgg taaaattttc cgaaagcgct gtttgatccg ctttgattac
    14761 aattccagta ttaatcgttt caagattgcc accttgatca atctcgccaa aggccgccat
    14821 aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa aacaacatgg atttatttcg
    14881 cagcagtatt tttgtgcgat atttataaaa atgccaaaac attatttccc ctcctctagt
    14941 ctctcaaatc cttgccagta atctctaaaa agacatcatt caaggacgct tctttggttg
    15001 ctatttttcc gtaactgatc ttttcttctt gtaagattgt aagaatcggc aacaatactg
    15061 tatttagttc agtagttgtt acttggagct gacctttttt ataagcgatt ccatcagaag
    15121 ctattgttcg ctgaatcgct gacaacacat tttctgggag taatgggatg tcgatcgtca
    15181 aacgatccgc cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct
    15241 gtccttgatc catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg
    15301 ttgtatagac aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat
    15361 tccgactttg ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt
    15421 gggcaatccc acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac
    15481 gaaacgaaac atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc
    15541 ttttctcttt ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta
    15601 gttcgtcaaa gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat
    15661 tttcaggagt cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag
    15721 aaagcataca gttgatggca gtcgatttcc cactgccgtt tggacctaac agacctaaga
    15781 cttctccttc ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt
    15841 tgactaattt atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat
    15901 ctgactataa taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca
    15961 tttgtcacaa tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt
    16021 ctactggtta tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc
    16081 tatttattga tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat
    16141 tggattttcc aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt
    16201 ctgccagcga cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg
    16261 ttaggttttt tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc
    16321 gtaattttgc tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt
    16381 gagaaaaagt acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa
    16441 caaaataaag cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa
    16501 cggaaccgaa ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt
    16561 ttacaaattg gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa
    16621 aatttaagtg ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc
    16681 catgagacat cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct
    16741 tctgttacga ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc
    16801 ttaatggtca tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt
    16861 gttttacatt ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc
    16921 agcccacaaa aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa
    16981 gaacaaaagg gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt
    17041 ttaccaaggg agggacacca atgataacag tagtcattat tgatgatgat ccatttgtga
    17101 cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat ccgtgtgtta ggcattggtc
    17161 attgtgccaa ggatgcgcga aacccatcgt cccgatgttt tgctgacgga catccgcatg
    17221 cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc
    17281 cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt
    17341 gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct
    17401 tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag
    17461 aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc
    17521 atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt
    17581 gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc
    17641 acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa
    17701 cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc
    17761 gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg
    17821 gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg
    17881 attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca
    17941 tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt
    18001 cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca tatcacactg
    18061 aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc
    18121 aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat
    18181 ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt
    18241 ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt
    18301 ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt
    18361 ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag
    18421 aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga
    18481 tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg
    18541 cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca
    18601 aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt
    18661 cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt
    18721 ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc actttatctt
    18781 cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg aatacattca
    18841 attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc
    18901 aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta
    18961 acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac
    19021 ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca atttgataag
    19081 catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc
    19141 cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct
    19201 gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag
    19261 gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa
    19321 tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca
    19381 aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc
    19441 ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg
    19501 ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat
    19561 ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt
    19621 tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag
    19681 cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct
    19741 tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg
    19801 aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt
    19861 gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga
    19921 tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg
    19981 gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc
    20041 gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt
    20101 tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca
    20161 aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac
    20221 gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca
    20281 tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga
    20341 ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga
    20401 ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt
    20461 cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc
    20521 cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct
    20581 ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat
    20641 tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg
    20701 gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct
    20761 aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca
    20821 gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc
    20881 tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa
    20941 agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt
    21001 gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc
    21061 aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa
    21121 gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc
    21181 tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct
    21241 ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta actttgtggc
    21301 aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc
    21361 ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact
    21421 ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta
    21481 gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc
    21541 aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc
    21601 ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca
    21661 tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta
    21721 cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca
    21781 ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc
    21841 tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt
    21901 gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt
    21961 atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg
    22021 tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca
    22081 ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt
    22141 ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa
    22201 taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg
    22261 ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg
    22321 tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt
    22381 ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg
    22441 acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga
    22501 gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa ccgcgttgaa
    22561 tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga
    22621 ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat
    22681 ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag
    22741 cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga
    22801 ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg
    22861 ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat
    22921 caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg
    22981 attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt
    23041 ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc
    23101 tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac
    23161 tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac
    23221 ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct
    23281 ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat
    23341 aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg
    23401 gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa
    23461 ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt
    23521 cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc
    23581 ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa
    23641 ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag
    23701 aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg
    23761 gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc
    23821 aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa
    23881 tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat
    23941 caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga
    24001 ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac
    24061 ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt
    24121 cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa
    24181 cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga
    24241 agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg
    24301 tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta
    24361 ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag
    24421 cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat
    24481 cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt
    24541 cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg
    24601 cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt
    24661 gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt
    24721 acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg
    24781 cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg
    24841 acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag
    24901 cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta
    24961 ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt
    25021 taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt
    25081 gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt
    25141 cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac
    25201 caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa
    25261 aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca
    25321 atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag
    25381 cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag
    25441 ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc
    25501 cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg
    25561 caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata
    25621 ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg
    25681 ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca catggattac
    25741 ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt
    25801 tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg
    25861 ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc
    25921 ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc
    25981 tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt
    26041 tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc
    26101 ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat
    26161 gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc
    26221 ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt
    26281 ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa
    26341 acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga
    26401 tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca
    26461 atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg
    26521 tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt
    26581 catccaaata actgatccga acatccagca agggataact aacactttgt tcccggttcg
    26641 ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta
    26701 aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga
    26761 acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat
    26821 ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct
    26881 ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct
    26941 ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac
    27001 cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca
    27061 gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta
    27121 taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt
    27181 tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga
    27241 taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc
    27301 atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac
    27361 atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc
    27421 cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt gacaaattca
    27481 atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc
    27541 aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct
    27601 gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt
    27661 actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc
    27721 gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac
    27781 gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt
    27841 tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc
    27901 gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca
    27961 acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt
    28021 tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa
    28081 accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact tttagctatt
    28141 gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca
    28201 tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct
    28261 gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca
    28321 aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta
    28381 gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt
    28441 gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa
    28501 gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat
    28561 ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa
    28621 cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt
    28681 caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat
    28741 gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg
    28801 aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa
    28861 aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc
    28921 tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc
    28981 acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat
    29041 acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc taattaaaaa
    29101 aggctctttg tcaaatgatg ttggtaaaga gaaatcttag aataatttgg acagaacaga
    29161 aagaagaaaa cctctttctg ttctgtttat ttggttaaaa atgttttgcc atgacgaatc
    29221 ataattcgta gtttgaaatt gtaaaagttg cgaaagccgt acgcattgcg ttttaatact
    29281 ttgatgtggt tgtttaagca ttccaatggt ccgtttgaat agctgtagtg aagcgcattt
    29341 tggatctgtg gcagaaactt tttaaacgtt cgtaaagtgg ttgtataggt ttctggcaga
    29401 ccgctaatgt ctctagttaa acaatcctca aatagtgact gatctctttt ctttaccgca
    29461 taaagaatgt cttggtataa ctgatagcct tggcgtaagt tgggacaagc agctaacagt
    29521 cgatcggcaa tctcactttc agtcaaataa tctttaaaac tggcacgcca aacccgtttt
    29581 tcatagttta actttgcttc ttctttttgt aggagtttcc aatagcgctt caattttttc
    29641 cctaaccctc gttgagagtg ggaatttcct ttaagtcgta ccgtggtttc tttcactcga
    29701 tgattcaaga aagttctgcc aatatgttgg acgatgtgga aacgatcgat gatcaactga
    29761 gcattcggga aaagcttttt caccaacgaa acataaggcg catacatatc aataacaatc
    29821 aattgaacgg cttcacgagt cgctaatgaa aaccgagaaa aatagcgttc taaataaggc
    29881 aagcgtcgat tttcgacaat atccaataat gcatggcttt gtccgtccat catgataaaa
    29941 ctcattgcac tggcaacact tcgaaccgat ttgaattcat caaagcataa gacctttggc
    30001 aaagtctgtt tgaaaggatt caatgggcgg tagaatcgct tcatgacacg atagaccgaa
    30061 gaagtggaaa tatttttctg acgagcgatt tccgtcatgg aagtattctc ttttaagcga
    30121 gcaatgacag accaacgaac tttttgacta atgaaacagt gtttttcagc aacagaggta
    30181 tccgctacga atgttctttg gcaagactta catttaaatc gttgtttctt cagctccaga
    30241 taagtgcgat actcagacac atcattcagt aacaaccgaa cggttgtcgt cccccaacga
    30301 atgatcctag aggggacgac acaaagacaa tgggaacact cttctggctt gtacagaaga
    30361 gttcctttgt aaatcaagca aatttgccct ttgtattttt ctttagttaa acaattttcc
    30421 tcgaaataga tatttaggtc tagaatattt agggtatctt tgataagctg agtatgagac
    30481 atcttgaatc ctcctatgaa ttggtagcca aattaattct aaaggatttc agggtgtctt
    30541 ttctatattt ttttatacaa aaaagatgtt ggtgaagttc accaacatca aaaagtatag
    30601 agc
//
LOCUS       DADVXE010000029        30016 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.029, whole genome shotgun sequence.
ACCESSION   DADVXE010000029 DADVXE010000000
VERSION     DADVXE010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.029"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(29..1261)
                     /locus_tag="KB913_001423"
     CDS             complement(29..1261)
                     /locus_tag="KB913_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBB6819791.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1516..2085
                     /locus_tag="KB913_001424"
     CDS             1516..2085
                     /locus_tag="KB913_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6819792.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2263..2703)
                     /locus_tag="KB913_001425"
     CDS             complement(2263..2703)
                     /locus_tag="KB913_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBB6819793.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2861..3625
                     /gene="map"
                     /locus_tag="KB913_001426"
     CDS             2861..3625
                     /gene="map"
                     /locus_tag="KB913_001426"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBB6819794.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3657..4580
                     /locus_tag="KB913_001427"
     CDS             3657..4580
                     /locus_tag="KB913_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBB6819795.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4805..5044)
                     /locus_tag="KB913_001428"
     CDS             complement(4805..5044)
                     /locus_tag="KB913_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6819796.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5049..5468)
                     /locus_tag="KB913_001429"
     CDS             complement(5049..5468)
                     /locus_tag="KB913_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6819797.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5695..6933)
                     /locus_tag="KB913_001430"
     CDS             complement(5695..6933)
                     /locus_tag="KB913_001430"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6819798.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7040..7675)
                     /locus_tag="KB913_001431"
     CDS             complement(7040..7675)
                     /locus_tag="KB913_001431"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6819799.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(8017..8652)
                     /locus_tag="KB913_001432"
     CDS             complement(8017..8652)
                     /locus_tag="KB913_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6819800.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9164..10306
                     /locus_tag="KB913_001433"
     CDS             9164..10306
                     /locus_tag="KB913_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBB6819801.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10299..10505
                     /locus_tag="KB913_001434"
     CDS             10299..10505
                     /locus_tag="KB913_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBB6819802.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10584..11777
                     /locus_tag="KB913_001435"
     CDS             10584..11777
                     /locus_tag="KB913_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6819803.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11982..13121
                     /locus_tag="KB913_001436"
     CDS             11982..13121
                     /locus_tag="KB913_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBB6819804.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13114..13914
                     /locus_tag="KB913_001437"
     CDS             13114..13914
                     /locus_tag="KB913_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6819805.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13914..14741
                     /locus_tag="KB913_001438"
     CDS             13914..14741
                     /locus_tag="KB913_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6819806.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14719..15453
                     /locus_tag="KB913_001439"
     CDS             14719..15453
                     /locus_tag="KB913_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6819807.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15553..16419
                     /gene="rfbA"
                     /locus_tag="KB913_001440"
     CDS             15553..16419
                     /gene="rfbA"
                     /locus_tag="KB913_001440"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBB6819808.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16433..17005
                     /gene="rfbC"
                     /locus_tag="KB913_001441"
     CDS             16433..17005
                     /gene="rfbC"
                     /locus_tag="KB913_001441"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBB6819809.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17027..18055
                     /gene="rfbB"
                     /locus_tag="KB913_001442"
     CDS             17027..18055
                     /gene="rfbB"
                     /locus_tag="KB913_001442"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBB6819810.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18153..19004
                     /gene="rfbD"
                     /locus_tag="KB913_001443"
     CDS             18153..19004
                     /gene="rfbD"
                     /locus_tag="KB913_001443"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBB6819811.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19038..21071
                     /locus_tag="KB913_001444"
     CDS             19038..21071
                     /locus_tag="KB913_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819812.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21115..22395
                     /locus_tag="KB913_001445"
     CDS             21115..22395
                     /locus_tag="KB913_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBB6819813.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22605..23411
                     /locus_tag="KB913_001446"
     CDS             22605..23411
                     /locus_tag="KB913_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6819814.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23423..24643
                     /locus_tag="KB913_001447"
     CDS             23423..24643
                     /locus_tag="KB913_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6819815.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24633..26219
                     /locus_tag="KB913_001448"
     CDS             24633..26219
                     /locus_tag="KB913_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6819816.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26258..28396
                     /locus_tag="KB913_001449"
     CDS             26258..28396
                     /locus_tag="KB913_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6819817.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28764..29747)
                     /locus_tag="KB913_001450"
     CDS             complement(28764..29747)
                     /locus_tag="KB913_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBB6819818.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
BASE COUNT         9589 a         5271 c         5965 g         9191 t
ORIGIN      
        1 tattttttgc atgtgtgcga aagtatactc aagcccaatc gccatttcgg aaaatcggta
       61 ctgtagagcc atcttcacgg attccgtcga tatccatctt gtcagatcct accatgaaat
      121 ctacgtgggt ttgacttcta ttcaatccag cttctgctaa ttcttcatcg gacatttctg
      181 taccgccttt cacactgaag gcataagcag aacctagtgc taagtgattc gatgcgtttt
      241 catcaaataa tgtattgaaa aagatgatgc cagattgaga aataggtgaa gggtcaggta
      301 caagtgcgac ttctcctaaa cgacgcgcac cttcatctgt atcaagcagt tttgctaaga
      361 catcttctcc ttgttcggca gaaaaatcaa caacttttcc atctttaaaa gtaaatttca
      421 tacccgagat gatggtgcca gcataactca gtggctttgt acttgaaatg taaccatcta
      481 ctcgatgact gtcaggtgct gtgaacactt cttccgtcgg catatttgcc atgaattttt
      541 ctccacgagc attatagctt ccagcgcctt cccaaagatg gtttttaggc aatccgataa
      601 tgatatctgt accgggagca gtatagtgaa gggcagaaaa ttgttctcga ttcaattctt
      661 ctgctttttt tgctaatttt tcatcatgct tcttccatgc taagacaggg tcttcttcat
      721 agacacgagt cgttttgaaa atctgatccc ataatgcctc aacttgtttt tcttctggca
      781 gttctgggaa gacttttgct gcccattgtt taccagccgc agccacgaca gtccaactga
      841 ctttatttgc ttgagttgcc ttgcgtaaat tcattagtgc tttgccattc gctgattgat
      901 aagacgctac tcgatggcta tctacaccag caaatgcatc gggatcggca gaaacaacgc
      961 tgatcctgct tgctcctttt tcaagccatt catccgcttg atcgatttta gattgtggta
     1021 cattctcaat acgatccgtt gcagcatgta aaagaaattc tctttggatc tggtcgtcag
     1081 tccattgaac gataacctca gcggctccta gtttataagc ttcttgtgtg atcaatcgag
     1141 caaggggtgc ctgttccacg ctgatctgta aaacaactgt gtgtcctttt tctgtggcta
     1201 cgccagtttc tgcaattaag cgtgcatatt tttttagaag ttcattaaaa tcagataaca
     1261 taataaaaat tcctcctcac cattttttct ggtaactatt agcatgatac catttaatta
     1321 tgattcaaac aatgaggctt taaataaaaa aaggaggtta tttttttaag gttaagtttc
     1381 atgatatatg ttactacttg ctatttcagc ttgtgaagaa aatcaaaaac taattttgca
     1441 tatcaaaaaa aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta
     1501 aggagattaa aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct
     1561 gcttatgaag tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac
     1621 aaaatgaatt gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga
     1681 caagctcttt ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat
     1741 acagggaata cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag
     1801 aagttgtatc gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc
     1861 tcttatactt actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa
     1921 gagcagatcg aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg
     1981 atgtcttcaa gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt
     2041 atagatgcta tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt
     2101 ccacaaatca gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca
     2161 gcgtatgcat ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat
     2221 acagattgaa taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag
     2281 ttctttagcg aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt
     2341 aacattttcg gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac
     2401 cgatttgcag aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc
     2461 caatagatcc aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc
     2521 atcatcgtat gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc
     2581 tacttgggta cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac
     2641 aatatcggcg atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc
     2701 catgatgtgc ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt
     2761 gaaaagaaaa taaaacctag agacacctgg ggaatgtcat ttggctaaat gtatgccgct
     2821 atgttaaaat gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc
     2881 acgtgaaatt gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct
     2941 gcgtgatttt ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta
     3001 tatcgagagt catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac
     3061 ttgtatcagt ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa
     3121 cggtgatttg gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg
     3181 ttgggcctat gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa
     3241 gaaagctttg tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg
     3301 tcatgctatc caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg
     3361 tcatggcgtt ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg
     3421 aaaagggttg cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg
     3481 aacttggaaa atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact
     3541 ttcttgccaa tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc
     3601 acaaggagaa gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga
     3661 aagtttggaa caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa
     3721 agcgcatcac tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct
     3781 tgtctttatt tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc
     3841 aagagactgt actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg
     3901 gtcctgcaat caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat
     3961 tagcggcttt atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag
     4021 cgtatggcgt agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca
     4081 ttgtcttgtt catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga
     4141 ttttggatgc tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa
     4201 ctttgaagtg gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa
     4261 ttgtccctaa tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg
     4321 tcggctggat gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga
     4381 tcagcggtta tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg
     4441 ctacgatcat cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc
     4501 atcaaatcaa aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat
     4561 tttctcataa aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat
     4621 ttgaaatttt atatctaatt ttcaattatc cgcataaaca ctatacattc aagcattttg
     4681 aagtatagaa aaacactcat cttaccacga atttaccacg attgaatgag ccttgatatg
     4741 accgtaaaac tactaaggga gatagcacga aactgtgtat ctcccgattt ttttatacag
     4801 ttgattactt cactccgatt tcaaatttca atattgcttt catcatgtct gtatgaattt
     4861 ctccttttag ttcttcatca acctgcataa tgattttacc actttcagag tggtaaaaag
     4921 gacgcaagca taatttagaa atataaccgt cataaaactt caaaatctct ttaactgcca
     4981 tttcatctcc gcttgacgct ttgcaaatca attcaaaaga gggatagcca taatctttac
     5041 tcatttcttt acttcctttc gctcaaaagc atttttaact tccttagtcc tctagttctt
     5101 ctactgcaaa tagcagaacg tgatacatgg tacagttctg aaatttctct gtcgttcatt
     5161 ccttgaaaat aacgtaataa aatcgcacta cgctgttttt ctgacagtct atgtaaaact
     5221 gtaccaagtg tttcatcaga tacataaatt gtaaagtgca agactttaaa tgatacacaa
     5281 tcataaaaac aggtatcaat cgttccacgt tcaacttgtt tcgtttcggc tatttcacaa
     5341 aacaatactt cacgtttaga atgtcttgca agctgtctgt ttcgactttt cactttgttc
     5401 ttaatgacaa tcagcattaa agaattgaac tgtaatctga cgatatgctc gaaagaagat
     5461 gtcctcataa tctcaccccc tttctgctaa tgctgaaata tataaacgga ataccgttta
     5521 taccctttag aaatacagaa aaatggtaag aaaaaagccc acacaaaaca tatatttgtg
     5581 cgagccttaa atactgcaat attactcttt cttttataac actatccttt tagcagattt
     5641 caaattttct tttatatatt gtttttagcc taacatacta tttaacccct tgtattatat
     5701 ctctaacttt tgaaaaattc tttttgaata tattgaaatc atgattgaag caatagaagc
     5761 tacaaacata acaacccatg tttcttgtat aaatacatcg aataaaatac cgtaaaccat
     5821 ttgtccaata ggttgaccgc acatagcaac tgctaccagc gtagccatta tctttcctac
     5881 taattgcggt ggtgtttgtg tctgaacaag agtgtaaatt tgaacaacaa acatagtaga
     5941 tacacccata gccacaaagc acatcactgt aactacccag taggaaacta ttgcaggcaa
     6001 ttctaaaaat agcgaaattc ccataagtaa aacagaaaca gaacaaataa gtaacaaggt
     6061 ataaaggttt tttagtttta actttgaagc aacaagagct gttaaaatac caccacataa
     6121 accacctaat gataatgctg attgtgaaaa accatatagt gtatctggca tttttaaaac
     6181 ttcagaaatt aagataggca gaccaacaat taaaacagca cttaaaacca aattgaaaat
     6241 gcaaaccaaa aagattacgg atataaaaat gggtttctcc tttttcaaaa aggtataact
     6301 atcttttaaa tcgtttttag caactgcaat tacacctact tcacgaggtc ttttttggtg
     6361 tggaatatgg ataaaaattt ccataatggc tgaaaaagta aaacatataa tactaacaat
     6421 taaaatggga ttgataccat aaaattgaaa aactactccg cttatagctg gtccgataaa
     6481 gtttgctaaa gtatttactt gatttattat agcattaccg acggtaagtt tatctgatga
     6541 taccaataga ggaatacttg cttgtaccgc tggttgatat gcaccagaaa taccataaag
     6601 taacatcaaa gcaacaataa acaaaggtat gataggaatt tttcccaatg acaaataaaa
     6661 tactaaaatt atgattgctg ttacaaaatc tagtatgacc ataatgtttc ttttatttgt
     6721 cctgtcagca ataataccac ctaccagcga caaaataacc ataggtaaaa aagagcaggc
     6781 tgtagcaata ccaaacaaag ctgatgaacc agtttctttt aacaaatagt acggtaatgc
     6841 aaatcgtagg atagcgtttc caaataaaga aattatctgt cctataacaa caagtataaa
     6901 atcacgatta aaaagttttt tttctgcttg cataaaatct ctccttttta tttaatcaaa
     6961 cagaccgtcg gtttatataa tggtttaaat aaactgctct tttatagagc agtctatcgt
     7021 atagggataa caaatacagt tatttacaaa actgtataaa tgcagaaatt gtttcttcgt
     7081 ctaataatgt gtctatgcct attccattta aaagggcatt gaatgtattg caacgttttt
     7141 ccataccctc tttatccgtc atttcaacta atgggttgag ccatacatta cttaatacca
     7201 tgataacttc tgcaatttca tgtgaatttt caatctccaa agacttatcc ttgatacctt
     7261 gttctaaaac gggttcaaca aattcaggta ctacaatttc atacatttgt tctatttgca
     7321 tagcaagaaa acgaggattg tttaatagtt gaggagaaac tgtcaataaa acgctttggt
     7381 tagaattgaa taccgctgtc ttaaatattt ctcttaactt ttctaaaccg tttaaactat
     7441 cgttatctct aattttagca aatattactg cattttcatt tccaattctt tgaaaaattg
     7501 cttttaaaat atcttccttt gaatcgaaat gatgataaat agcaccttta gaaagttttg
     7561 tttcattgat aatatcttgc aatgatgtgt tatcatatcc tttttcacaa aacatttttg
     7621 tagaaacatc taaaatgagt tttactgttt cttctggata tttatttcgt gccataactt
     7681 acctccaata caaaccgttg gtctgattaa agtatatctt agtattttat gcttgtcaat
     7741 ataaagactt gcaattttat aaaaatgcag aatgcaagcc tttttcattt attctacaat
     7801 cttccagttg ctttccttat gcggtgtcaa ttcatactgt gatacctgcg ttgcctttgc
     7861 ctgatttacc acaaatcaga ttttatccct ttcttcctct tgattgccca caacagaaaa
     7921 gaaaaagccc tgtcaagagc tttgccacca ttggtggtgc tttgcactct tgatcgggct
     7981 ttttgtttgc tgtatcttct cgcaagagga aaaaagttac tcgtcctcat catcaaaatt
     8041 gttattcctt aatacttctc gtaacagttc catatcttct tttgagttcg ggtttatcat
     8101 tttcacgact tgataaggtg tcttatactt atgtccctct atgctttccc caaacatatc
     8161 catactgtat aaatcatcat agcggtctaa taatttttga aacttcaaat gctggataaa
     8221 ttctttgatt gggtaaaggt cggacgcttc aatgcttttc ccgttgatat agtctgtaat
     8281 atattcccgt aacttttcta actcatattc cagccattct tcctcgctgt caaagaagtt
     8341 atcatagtgt ccatgtttca gttctgcatt tagacgttct tcggctctta aaaactgaca
     8401 gacttccttt tcagattgat tgacatactt ccattctccc gacaacaatt cattgggcgt
     8461 aacgtccagc acttccatta tcttttccag cgtttcatag gcaggatagt tcaaccctct
     8521 ttcaatcttg gaaaggctct gcatattgat accgattttg tccgcaagtt cctgttgttt
     8581 cattccccta aattttctta tggtctgtat attatttcct aaatggctta ttttcattgc
     8641 ataaccctcc atatctcgtt atatcttcgc tattataagt ctatcatgct taatatgatt
     8701 tgtaaaggca aaaaaagata ttgacaaata agcatataag aattactatg ttcttgtaat
     8761 cgaataagca caatagaatg aaatataaaa acattcaaaa agaaatacct atctgattaa
     8821 atccgtagat atgaatatcg gttgaaatgg aacttgttag aaaaggcaaa acagaacttg
     8881 ctgacaaagt atttctgaca cggtggcgga agcctctcag gcttaccgcc atgacacctt
     8941 gtgtcaaggg gaagaaatgc tttgtcggct ggcgagcctg cgagccttgt ctgtgccccc
     9001 gttatctaac aggggggcac tatttcacaa aagacaagtc aaaaaccata cacccccaaa
     9061 cctgtgagta gtaatgagag gttttaagaa gatagtacat atcacacttt ttgaaaggtg
     9121 gtttacaggt atttcaaggc tattgtggga ttggaggaat acaatgaaca atttagaatt
     9181 tgcacttgaa atgaagaaca aacgtcttgc cagcggtctt tcacaaggag aacttgcaag
     9241 tcttacccat gtatcaagat atagtatcaa ccgctttgag aacggaaaag ctaacgccag
     9301 caaggaaaca cagaacatta tcctgcgttg tctgaattac tatatctgcg ataagccttt
     9361 ttatctgctc gttgattatc tgtctgtccg ttttccaacg actgacgcat tggaagttat
     9421 ccgaaaggtg cttggcatga aagcagatta ttttatccat tatgactatg ggtattatgg
     9481 ctataaggag cattatgctt acggggaaat caaggtcatg gcttctgatg atgaacacat
     9541 gggcgtattt ttagaattaa aaggggcagg ctcacgcaac atggaatatg tcttacaggc
     9601 acagaacagg gactggtatt cattcttaaa ccgctgtctt gactgtggcg gtgttatccg
     9661 acgttttgac ttggcaatca atgatatgtg cggtctgctg gatattcctg tgctatctga
     9721 aaaatacaga aatggtggtg cggaatgtcg ctgtaaaaac tatgaaaatg tacaaggtgg
     9781 aaaattaagc ggaaaaaacc gtaatttagc aagtaccctt tatatcggct caaaggcaag
     9841 cacaaaatat ttctgcctgt atgaaaaaca aaaggaacag gcaacgaaaa agaaacatac
     9901 cgatattatc aaccgttttg aaattcgtct gcgtgacaaa aaggcggtac aggcagttga
     9961 agaactgtta ttgacgtata accctcatgg gctggtgttt tatctcatta ccgattttgt
    10021 ggaatttcct gactatccat tgtgggagat attcatttcc catgacagtt taccttttga
    10081 aatgaaccct gtacctgtca atatggaacg cactctgcaa tggctggaaa gacaggtcat
    10141 gccgtcaatc gtgatgatag aggaaatcga caggctgaca ggttcaaact acatgaaaat
    10201 gattgatgaa tgtacccacc tttctgaaaa acaggaaatg cttgtggaac agatgtgtac
    10261 ggacatatca gacgtaatcg aaagtgaggg ggtgttttat gagtaataca caggatattc
    10321 ccgtatggga aaaatacacc cttaccattg aagaagcgtc aaagtatttc cgcattggag
    10381 aaaacaagtt aagacgattg gcagaggaaa acaaggacgc tggctggctc attatgaatg
    10441 gcaaccgcat acagattaaa cgccgacagt ttgaaaaggt tattgataaa ttggacgcaa
    10501 tctaatgcaa atgagccttg tatgtgttat gatgaacaca agtcatatca aggctctttc
    10561 caacaaggaa aggagcagac accatgaaag aaaaaagacg ggataacaaa ggtcgtatcc
    10621 tgcatactgg agagagccaa cgaacagacg gaaaatactt atataaatat gtagacgcat
    10681 tgggaaacac aaaatatgtg tatgcttgga gattgacacc cacagacccg acaccaaagg
    10741 gaaaacggga aaaaccctca cttcgagaac tggaacagca gataagacgg gatattgagg
    10801 acggtatcga cagcacaggc aagaaaatga cgctttgcca actctatgcc aaacagaacg
    10861 cacagaggac aaatgtgaag aaaagcacac agaaacaacg ggaacaactc atgcggttat
    10921 taaaagagga caagttaggt gctaggagca ttgatacgat aaaaccctct gacgctaaag
    10981 aatgggcgtt acgcatgaaa gacaaaggct tttcctacaa taccattaac aaccataaac
    11041 gctcgttaaa agcgtcattc tacatagcca tacaagatga ttatgtgagg aaaaaccctt
    11101 ttgatttcaa gctaagtgaa gtcatagaaa atgataccaa agagaaagtc gcattgacag
    11161 aggaacagga gcaagcctta ttgtcattta ttaagacgga caacgtgtat cacaagcatt
    11221 atgatgatgt gctgatactg ttaaagacag gacttcgtat ctcggaactg tgcggactga
    11281 cagtagccga cattgatttc aagaatgaag ttgtgattat cgaccaccag ttactaaaga
    11341 gtaaggaaca gggctattat attgaaacgc ctaagacgaa aagcgggata aggcaagtgc
    11401 cattaagcaa agaaacgata caggcatttc aacgggttat caacagccga ccaaagataa
    11461 agtcgataga ggtagacgga cacagcggtt ttgtgtttat caatccgaaa ggtaatccaa
    11521 aagttgccat tgattataac gccttattta tccgtatggt aaagaaatac aacaagcacc
    11581 acaaggacaa tcccttgcca catattacac cgcatacgct acgccataca ttctgcacaa
    11641 ggctggcaag caagaacatg aacccgaaag atttacagta tatcatgggg cattcaaaca
    11701 tcagtatcac aatgaactgg tacgctcatg cgtccataga taccgcaaaa tcagaggttc
    11761 agcgtctaat cgcatagaag tatttaccac gattttaacc acgattgaca gggaaaatat
    11821 aagaagatag acctagatat gcgaggttta ccacaaaagc aaaatgcccg tagagccgat
    11881 aaaataaggc tttgcggaca tttgagaaga tataaaaaga tagtcaaaaa gacatatata
    11941 atttataata attatgactc ttaattaaag taggtgccca tatgcttgtt tcttttagta
    12001 tggttataag attttttctg acaattttat tatcactgat attaacacct gtattcaaaa
    12061 tcatttcagt acaaacaggt atggtcgaca aaccaaatga aagaagaata aataaagttc
    12121 caatgccttc agcgggcgga ctgcctatct ttatttcatt tgttatatcg actttattct
    12181 tattccgtaa aattatccct caatcgtata ttgtaccgat cttgattgct tctttagtaa
    12241 tcatagtcac aggagtgctc gatgataaat atgagctgac acctaaacaa aaaagtatag
    12301 ggatcttgat tgcttctctt attatttatt ttgtagcaga tatacgtatt gattccttca
    12361 cgcttccttt tattggatat atccaactag gctggcttag ttttcccgta acgatttttt
    12421 ggatcttcgg tatcacgaat gcggtcaatc tgattgacgg tttggatggg ctggcggcag
    12481 ggatttcatt gatcggttta attacgatag gaatcattgg atattttttc ctccatgctt
    12541 ctacagtgta tattccagtt gttattttct gtcttgtagc aagtattatc ggtttttttc
    12601 cttacaattt ttatccggca aagatttatt taggcgatac aggagctcta ttcctagggt
    12661 ttatgatggc cgtcctttca ctacaagggc tgaagaacgt gacttttgtt tcatcgattt
    12721 ctttgctgat cgtcatggga gtgccggtaa cagacacgtt ttttgctatc attaggagaa
    12781 aagcaaaccg tgtttctttt tctacagcag ataaaaaaca tcttcatcac cgactaatca
    12841 gtttaggctt tactcataaa ggtgctgtcc tgacgattta tgcgatggct ttgatgtttt
    12901 ctttcacagc tatggtcatg aattatactg gaagaatcgg aacgatcata ttgattattg
    12961 ccatgttgtt tgctgcaatt ttattatttg aattgattgg tctgatcaat gagaaacatc
    13021 agtttatttt aaaaacattg cgatttttag ggaataaaga gtaccgtacg caagtaaaac
    13081 agaaatattt gaagaaatgg aaccgtcata tagatgaata acaaattaaa ccagccgatc
    13141 cttattagta ttgtgacggc aaacagtgat aaaatttttc ggacactaga taattttatt
    13201 tcaactgtaa aagatgaaac agcagtaaaa atccgaattt ttgacaacaa ttcacttccc
    13261 gagtacaaaa aaagactaac agagtatagg aaatatccct acatcgatat ctattttcat
    13321 gatgaaaatt ccggatttgg ttatggacat aatcacaatc tgatagctag cgattctcgc
    13381 tatggcatta tttgtaaccc agatatttta gtggatgaag agacagttac agcattggtc
    13441 ttgttattga aagaacatcc ggaatgtgcg atgttagcac ctaagattct taatgaagat
    13501 ggaacaactc agcacctcat ccgtgagcag ctggctgttt ttgattacgt tttgcgcttt
    13561 gtgcctttca aatgggtcaa aaaaaagttt gacaaacgac tggctgtgtt tgaatgccga
    13621 ggattgccta ctgatgctaa tagttatgta cggatgatct caggtagttt tatggtagct
    13681 gatattgata aatttaaaga gataaagggg tttgatgagc gtttcttcat gtactttgaa
    13741 gacaacgact tgtgtttgag ttttgaaaaa gcaggttaca agttattgta cacacccttt
    13801 tatgcagtta tccattttta cgggaagggt gcgcatcgaa atgcaaaact gtttcgcgtg
    13861 tttttgactt ctatgatgaa atttttcaat aagtgggggt ggcgtttttt ctgatgaaac
    13921 cagaaatatt agtagtcgtt gtgctttatc agcaactatt cagtcaatct ccagcttatg
    13981 gaccattaag caaagcactt agcgaaaagc aaattcagct tattatttac gataatagtc
    14041 ctcaaaggca gcaaaatgag ctgtttgaaa aagaaaatat cgtttatcat catgatccgc
    14101 aaaatcctgg tttagcggtg gcttataatt ttgcgttgtc tcaagcagat gaaggaacac
    14161 gttgtctcgt cactctggat caggatacga ggctagtcga cgattatttt gaactattgc
    14221 gtaaagtaac ctttacagat gaatgtgttg ctgcagttcc gatgattttt tctgggagcc
    14281 gacaagtttc tcccctatat tcagatcgtt atatcaatcg tacagctcaa gcagtagaag
    14341 ttgaaggccc aacagctgaa cgaatcatgg caatcaattc aggtgttgcc tggtctgtca
    14401 aatttctaaa aaagattggc gggtttaatc ctgctttttc tttagatttt ttggatcatt
    14461 ggctgttttg gaaagtggat cagttggaaa aaactgtgga gatccttcct gtacgaatgg
    14521 aacatgatct ttcggtttta gactatgaaa aagtttcaag taatcgatac cgttctattt
    14581 tacaagcaga aaatcgattt tatcatgaat atgatcaaag gcatttatcc agtcaccgac
    14641 gacaattatt gttaagaaca gctaaacagt tcttgaccgt caaaaaccgg catatctggc
    14701 ggatgacttt gcgctcatat gttaagaatt ggaaggtgtg aattcgtgcg ttcggtttgt
    14761 atagctacct ttaatggagg cagatattta agagagcagt tagatagtat tttatctcag
    14821 ctttcagcag aagatgaagt agtcatttct gatgatgggt cagtagatga tacatgggat
    14881 atattaactg aatacgcaga aaaagataag cgaatccagc ttttttcggg gcctcgtcaa
    14941 ggattgatcg ctaattttgg ttatgcgatc cagcagacga aaggagatct aatctttttg
    15001 gcagaccaag atgatgtttg gttggagaca aaagtgaaaa agatcactga ctattttgag
    15061 cagaatccgg atcagctagt agtagtttct gatttaatca ttgtggacag cgagctgcaa
    15121 gagatccatg attcgtattt ttcgtttcga aattccaaag aaggatggct taataatgtg
    15181 ataagaagtc actatattgg tgctggtatg gctttccggt cttctttaaa acccgatatt
    15241 ttgccgatcc cgtcagaagt gccgatgcat gatatgtgga ttggtttgct gggaggaaag
    15301 aagactgggt tcctaagaga accgttaact ctgtaccgaa gacatgattt aaacgcgagt
    15361 gagattgaaa cacattctaa attacggcaa aaaatttctt ggcgtgttca tctgattacg
    15421 gcgttgatca aacgaaaatg gtttaaacgt tgataaaaga tgtttaaatc cttaatattt
    15481 ccatgacaaa tataacaatt gatgagataa taacaaagtg aaatttgaaa tcaaaaagga
    15541 gagcagatat ccatgaaggg aatcattctt gctgggggca gcggaacacg tctgtaccct
    15601 ttaacaaagg caacatcgaa acaattgatg ccgatttatg acaaaccaat gatttattat
    15661 ccaatgtcta ctctgatgtt ggcgggaatc aaagaaattc tgattatttc aacgccacaa
    15721 gatacaccac gtttcaagga attatttgga aacggaaatg atttaggact gcagatcgaa
    15781 tatgcagtac aagaaagtcc agatggattg gcacaagcgt ttatcattgg agaagaattt
    15841 attggagatg atagtgtctg cttggtatta ggggacaata tttactatgg tggcggtctg
    15901 tctaaaatgt tgcaacgagc agcttcaaaa gatacaggcg cgacagtatt tggctatcat
    15961 gtcaatgatc cagaacgctt tggtgtagta gaatttgatg agaatatgca agctttgtcg
    16021 attgaagaaa agcctgctca gccaaaatca aattacgctg taactggcct ttatttttat
    16081 gacaatgagg taatttctat cgctaaaggt atcaaacctt cagaacgtgg agaactagag
    16141 attacggatg tcaataaagc atatttggat aaaggaaaac tatccgtaga acttatggga
    16201 cgcggatttg cttggcttga tacaggaaca catgaatcat tgcttgaagc atctaccttt
    16261 atcgaaacaa ttgaaaaacg tcagaactta aaagtggctt gtttggaaga aattgcttac
    16321 cgtatgggct acatcgataa ggaacaattg ctggcccttg cacagccatt gaaaaaaaat
    16381 caatacggtc aatatttatt gaatttggcc gctgaataag gagtccttac agatgaaagt
    16441 aacagataca aaattaacag atgtcaaaat cgtagaaatg gacgtctttg gcgatcatcg
    16501 cggtttcttc acagaaagtt attcaaaagc aaaatttgca gaacatggat tgaaatatga
    16561 ctttgttcaa gacaaccatt cactatcagc tgaagctggt gtccttcggg ggcttcattt
    16621 ccaaaaagga gaagctgcac agacaaaatt gattcgggta gtcactggag cagttttaga
    16681 tgtagtagtg gatatccgca aaggtagccc gacttatggt caatgggacg gatttatctt
    16741 atctgaacat aatcatcgac agttgcttgt acctaaagga tatgcccatg gattcgttac
    16801 tttgacacca aatgtgaact tcctttataa gtgtgataat tactataatg cagaagcaga
    16861 tgggggcatc gcatttgatg atccagattt agcgattgat tggccaattg atccatcaag
    16921 agcgattatg tcggaaaaag atcaccgtca tccgacatta aaagaatttg aagcagaaaa
    16981 tccatttgtt tacggagaaa tctaagaatt aaggagaaat tttcttatga aaaacatcat
    17041 tgttaccgga ggtgccggat tcatcggctc taatttcgtt cattacgtgg taaacaatca
    17101 tccagaagtg catgtcactg ttttggataa actgacttat gcaggaaaca aagagaactt
    17161 ggctggactt cctagcgatc gcgtagaatt ggtcgtagga gatgttgcag atgcagaatt
    17221 agtggaccgt ctagtaaaag aagcggacgc agttgttcat tacgcggcag aatcccataa
    17281 cgataattca ttaaaagatc ctttcccatt tgtacaaacg aatatcattg gtacgtatac
    17341 acttttagaa gcttgccgca agtatgatgt acgctatcat cacgtatcta ctgacgaggt
    17401 ttacggcgat cttccattac gtgaagacct gccaggacat ggggaaggcg aaggagaaaa
    17461 attcactgcg gaaacaccat ataatccttc aagtccatat tcttctacaa aagctggttc
    17521 agatctgtta gtaaaagcat gggtgcgttc ttttggctta cgtgcaacca tttcaaactg
    17581 ttcaaacaac tatggtcctt atcagcatat tgaaaaattt attcctcgcc aagtaacgaa
    17641 tatcttaagc ggtattcgtc caaaattata tggcgaagga aagaatgttc gtgactggat
    17701 ccatacgaat gatcattctt cagcagtgtg gctgattttg acgaaaggca gaattggcga
    17761 aacctatctg atcggtgcag acggtgaaga agataataag accgtgatgg aattgatctt
    17821 agaaatgatg ggtcaaccaa aagatgcgta cgaccatgta aacgaccgtg caggacacga
    17881 cttgcgttat gcaatcgatt cgacaaaatt acgggaagag ttaggatgga agcctgagtt
    17941 tacgaacttc cgtgatgggt tggctgacac gatcaaatgg tacgaagaac atgaagactg
    18001 gtggaaaaaa gaaaaagagg ccgttgaagc agcatatgcc aaaaatggac aataatacag
    18061 agaaaatgtc actgtattaa tggaaaaaca catgtgaggc aggcgctcgc ctgtctcttt
    18121 tttaaaataa aaatcaagga gcggataatc atatgttttt attaactgga ggaaatgggc
    18181 aactaggtac agaattgcgc catttattag atgaaaaaaa tctgcaatat gtttcaacag
    18241 atgcaaaaga cttggatatc acagatgccg agaaaacaat ggcttacatc acagaattaa
    18301 aacctgatgt tattttccat tgtgcagctt acacagcagt agataaagca gaagaagaag
    18361 caaaagaatt agatgagaag atcaatgttg atggtacaag aaatgtagca cttgcagcaa
    18421 aagctgtgaa tgctcaattc gtctatatca gtacagacta tgttttcgat ggaaaaaaca
    18481 aaaatgtaga atacgaagta gacgaccaaa cgaatccact aaatgaatat ggtcgtacga
    18541 aattattagg cgaaaaagca gtagaagaga ttttagaaga ctattatatc atacgaactt
    18601 cttgggtttt cgggatctat ggacacaatt tcgtcttcac gatgcaacgc ctagcggaaa
    18661 cccgcgacaa actgactgta gtaaatgacc agtttgggcg accaacttgg acacgtactt
    18721 tggcagaatt tatggtatat gtcatcgaag aaaaagcacc atttggtatt tatcatttgt
    18781 cgaacgaaaa tagctgttct tggtatgaat tcgcaaaaga aatattgaaa gatacagatg
    18841 tagaagttgc acctgttacg tcagaagaat ttccgcaaaa agcaacacgt ccgcagtatt
    18901 cagtcatgag cctgaaaaag acagaagagt taggatttgt cataccaact tggcaagaag
    18961 cacttgcgca aatgctggaa gctgccaaaa aaatgaataa gtaatttcct tttatcaaat
    19021 agaatttgga gcatgatatg gaaaaacaaa caagaagtgc acgacgaaaa gaaaagccaa
    19081 aagcgaacca ggcagattcg aatttggtgc ttgacctgtt tctaaaactc cgctatctta
    19141 ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt aaacggaagt tcacttggtg
    19201 tttgggataa atatgtgtcg caaagagacg atgggaaaaa aactgatgtg atttttggac
    19261 agaatcggga agtgcggtca gacgaatggc tggtgcagac acctttttac ctctcacaag
    19321 ctgaagagga ctttccgttg gtgaacgagg attattcatt aaacggacaa aacatgatca
    19381 ttgcgtataa ttctcctgta aaggatatta cggttatcgg aaaaccattc aactggggat
    19441 tctttttcct cggaagagat cgaggacttt ccttttattg ggcgatgaaa ttagtcgtca
    19501 tggtcttgct tggattcgaa gtactgatga tattaacgaa gagaaaaaaa gctctatcgc
    19561 taatcggtgc atttgcgctg acattttctc cagcagtcca gtggtggttc atgcaacatg
    19621 tgggcgattt gattttcttt actttgggac tgatgactgc tttttatcat tatttctaca
    19681 atcatgataa aaaatggcta cgaacgttga tgatgctttt ggtggttatt ttcggtattg
    19741 ggtttatttt agtgatttac ccagcccatc aagtgatgct ggcgtacttg ctgatttttt
    19801 attttgttgg cctgcttatt tactatagca agaaagtttc atgggatctg ttggatgtag
    19861 tgttgattgg aggggcagtt ttatttattg gcggagtcat ggttcatttc tggctaacgt
    19921 caaaagacgc attgttagct tctttgaata ccttatatcc aggaaaacgg gtaagtactg
    19981 gaggaaagtg gacgattggc gaattttttt ctttccttac aaattggaaa attccttttg
    20041 aagatatcaa ctattcgaat aactctgaag tggccctgtt ctatcacttt tttccaactg
    20101 tattcctagc aagtccattt gtgttatttg gcaaaaaaga tagcgaacaa aagttactgg
    20161 gacgtatttt gatgattttt tgtctgtttt ctatcttttg gattaccgtt gggttgccaa
    20221 aatggctagc agaaatcact ctgctgtctt atgttcctcc attaagagcc atccttactt
    20281 ttagttttgc ggcttgttta ttatcgatct ggtttatcgc ttatatttgg agagaagatg
    20341 ttattcctat ttggtataaa ttcattttgt tggcagtaaa tgcatggtct tatttctatg
    20401 cgattacgca ttcgaaaatg gataattatt tttcggattt tgaaaccatc gcagttgctg
    20461 tgttgggaac agtgatttta gcttttgcat tatttggctg gagacgcttg ttttacctcg
    20521 cttttgccgc cttagttatc gtatctggct ttttcgtcaa tccagtcgta gaaggtacag
    20581 gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa aatcgatcaa caagatcctg
    20641 gtaaagtttg gttgtctgaa gatgaattat ataacttcac cccaacattg ggagtgaaat
    20701 ccttcaatac agtacgcttt tatccagata tagctgcatg gaagaaaatc gatccgaaag
    20761 aagaatacga gaagtattat aatcggtatg ctcatacaag agcttttatc gctaaggaag
    20821 atacaaagtt cattttagat cgtccagata tgttttcggt cacgttgaat tttgaagacg
    20881 cagaaaaatt agggatcgac tatgtgatca gtaaacgacc attaactgat tacaaccaat
    20941 tatatgaagc gcagttcacg cagctatatg gaccggataa agacggttat atgattttta
    21001 aagtagaata tccggattat ccagatgtac cacaaacaca aactcaggaa aatcagctag
    21061 tcgtacagta ataggctagc tgagaataat cctgaaatgt tagtagaaag gagagtggag
    21121 ataattcaag caatcgtaca aaaatttgtc aacaaaatga gtgtcggttt cttgcttttg
    21181 ttactgacgc tagtcttttt tgtttggaca gcagggttag gttttccagc aactttgttt
    21241 atatataaca atagttcatt acttatcgct tttagtgtgg ctattttgct cattttaaat
    21301 gtttataaag caaaaggcgt cgattttctt tatctaggtg ttgcgcttgc ccttttcatt
    21361 ttcttttctt actttcggga attaagaaat gagtctttat ttggagactt actgtttcct
    21421 ttgattattt tattttgttt agtaattaaa tggatcgagt ggacaaaatg ggatcgcggt
    21481 atttatctga ttgtcttttc ggtcttcctc ggaatcacgt tatatcgtgt atttacagag
    21541 atccaagtac cagaaggaca aagcatctgg gctccaggca attcgctttc tgatatttgg
    21601 atcaatacga atataatcgg aagttctttg atgactcttg ctttattgat cagtggattt
    21661 gccagttctt ttgaacgatg gtatgtacga atcatcggtg cagtagcagt tgttgcagct
    21721 tttctcggga tttgggtctg ccaatctaga ggtgcattag tcgcgttgat tgtttttgcg
    21781 atattggatc ttttacctaa atcgttgatg cgtgtcattc gtgcgccatt tattgcttac
    21841 acggttacga ttcttttagc tttgccgatt tcttatctgg cggctgtctc tgaaaaagtc
    21901 aatttgttta ccggtcgaga agatatttgg cataaattct atcagacgct aggagaaaaa
    21961 tctgaacaaa ttttactagg aatgaaaaca tttatcttcc aacgaggaaa ccaattttta
    22021 ggaaaccaca atagttataa ttctattttg aatatctatg gattgatagg atttgggatt
    22081 gctgctttgc tgcttatcct ttttattggt cgcttaacgt tgaaagcaga tttatccaac
    22141 gggcagatga cttttatctg ggcctttttt gcggtgatga tgcagtcatt tatggaggat
    22201 acattgactt catacccatg ggttccgatt atttatatcc tgttggctat ggccgttcat
    22261 cgatatgatg aaccagaagt tgcggaggaa ttctatgtta tggaagaggc atatgacgat
    22321 atgacttatg atgatacatc ttatgaggaa caaccagata gcgctcattc ttccaggatc
    22381 caacgctatc attgataggc acaaaatacg agagaggctg tgacaaccgt cgcagccttt
    22441 tttggtttat tgcaattgtc tagcatcttc tgtaaaatag aaacgttaga gaaaatcttg
    22501 tatcatagaa aattaagaaa gaaataagaa cgcagctcgg taccaaaaat atggtaaaat
    22561 ggcacttgac tgtaattcac tgaaaatcgc ttggaggaac acaaatgttt aaagatttgt
    22621 atttatttat gaaggacatt tatcagaaca gaaaattatt gctacagttt tcgatcaatg
    22681 acttcaaatc aagatatgca ggatcgtttt taggaatctt atgggcgttt atcaatccgc
    22741 tatttactgt attgatttat tggctggtat ttggtgttgg actgaaagca caaatgatcg
    22801 atgcaaaata cccatttatc gtatatttag ttaccgggat gattccctgg ttcttcttct
    22861 cagatgcatt tgcatcaact acggttgttt ttcgggaata tacttattta gtaaagaaag
    22921 tcgtattcaa tattcgtatc ttgcccacga cgaaaatcct atccaatctg tacacccact
    22981 tattcttcat tctgattggc atagctgtcg cgcttataaa tggtatatat ccttcagcaa
    23041 tgtctttaca gctgatttat tatttatttt gcatgtgtgc tttcttgaca ggattgactt
    23101 ggctgacggc atcgatccaa ccatttttac ctgatatcat gcaattaatt acgatcgtgc
    23161 tgcagttgat catgtggaca ttaccgatat tatggagccc taatcagttt gattcaggtc
    23221 ttgtaagcat attgaaatta aatccgctgt actatgttgt tcaaggttat cgtgagtcat
    23281 ttttaagtga agcttggttc tgggagcatg gaacatatac tttgtatttc tgggttttca
    23341 cgttagtaat gttcgtaatc ggctctgcag tgttccgtag attgaaacca catttttcag
    23401 atgtgctgta aggagaatag ctatgacaga atatgcaatt agactaaaag atatcacaaa
    23461 atcttataat atgtacgcaa aaccttcgga tcgatttcgt gaagccctca atccttttaa
    23521 gaaatcctat catgatgtat tttatgcgtt gaaaaacgtg aatgtagaaa taaaaaaagg
    23581 tgagatgatc ggtttcgtgg gagaaaacgg atcgggaaaa tctacaatgt tgaaaatcat
    23641 tacgggagta ctgacaccaa catccggcac gatggaaatc gaaggaaaaa tctcagcttt
    23701 gctagaacta ggatcaggat tcaatcctga gtattctggc tatgaaaata tctatttaaa
    23761 tggaatggtt ctaggatttt caagagaaga agtcgatgaa atggtcgatg atatcattga
    23821 atttgctgac atcggagacc atatttatca acctgtaaaa acttattcaa gcgggatgtt
    23881 cgttcgtcta gcttttgctg tagcaatcaa tgtgaatccc gatattttga ttgtggatga
    23941 agcattggca gtaggcgatc ttgaatttca actaaaatgt atggaaaaat ttacagaaat
    24001 caagaactcg ggaaagacga ttttattcgt ttctcatgat atcagttcga ttcgtcgttt
    24061 ttgtgatcgt tcctattggt tgaaaaacgg agaagtcgtc gaatatggcg atacgatgga
    24121 agtaacgacg aattatgaaa actttttaaa gaaaaaatca gttaaaacag tggatcggaa
    24181 taaaaaccaa gtagaacggt tcgccgctcc agatatcgtc gacgtgacga aagcggaatt
    24241 gttggataaa gacaaaaatc cggtggatat gctggaacaa ggagaaaaac tatacgttaa
    24301 agtaacttat gaagtaaaag atgatacaat caaaaatccg gttttaggaa ttgcgctacg
    24361 aacagtcgac aatttttatg tatgcggact taatactcta ctagatggta tcaagattcc
    24421 ttggaaaaaa ggagagaata tcttttatct ggagtatgaa aagttaggtt tgttagctgg
    24481 tgaatattat tttgacgttg cggtctttga agaaaatgca acggttcctt tggtatataa
    24541 gacaaagtac atgaacttgt ttgtcagcgg ttcttatatc ggagaaggca tcgtggtctt
    24601 agaccataaa tgggaagaag ggactcatag caatgaaata tgattttgaa atggacctag
    24661 atgaacaaag cagtgtggga aaaattgccg cacagatcaa accaggaagt aaagttttag
    24721 agtttggtcc cggaaacggc cgattaacga aacatttaat cggagcaaaa caatgtgaag
    24781 tgagcattgt tgagttagat aaggaattgt tcgattttgt cagcgaattt gctcaagatg
    24841 gattttatgg tgatatcgaa agttttgagt gggcaaacta ttatgctgga cagacatttg
    24901 attacgtctt gtttgcggat gttttagaac atttggtaga tcctggaaaa acattgaaga
    24961 aagtcagaga atttttgaat gaagaaggag agatcctgat tacattccct aacttggcgc
    25021 ataattctgt catgatcgat ttgttcaata accaattgcc gtgggcttct tatggtctcc
    25081 tagatgaaac ccataattct ttttatactc atgatggctt ccaaaaagtt tttgaaaaag
    25141 cgggattatt cattaatatt gaagattatt tgtacttagc tgtaggtgat acagaattaa
    25201 aatcaactta tgaagaattg ccggaagctg tacgctatga tttcaaaatg cgaccatttg
    25261 gtgaagtcta ccaatacttt ttctcattga tgaaacatcc agtagcacaa agttccattg
    25321 cagagccaca aaattctaat tatgtaaaag tgttagaagt aacccagcaa acgaaacaag
    25381 atgaaacaat ccaacaaata ccattcaata atttcacagg ggaaaatgag acactaagtt
    25441 tccccgtatc agaaacaaca gaaagaatgg tgtttcgctt cgcgcaacaa cctagcttta
    25501 tcgaattcag cgcagaagct gccggagaaa aactaacatt tatcgattcg aatgctgtag
    25561 tcaaaacagt aaatgattgt tatttgtttg atgggaaaga attaccagag ttcgttctaa
    25621 cggatatttc tgggaaagaa gtgactatcc attgtcacta tcgctttatc ggggaattga
    25681 caccaacaat gaaagaattg ttggaaacga ttcgtcccat ggctgaagtc acaaagcagc
    25741 tttctgagaa aaatgacgaa ttagaaagag aaaatcatca tcttcttgag gaaaatacaa
    25801 gactagacca tacgttaaaa acaaccacaa atcgctattg cacattgttg gaaagtgatg
    25861 aatggacaat aaaacataga ctaggacgac gtaagaaaga aacttcgaaa aaaatccaag
    25921 aaaaagaact ttctatatgt attgacgaga aaatctggga tgcagaaaca aaaatattaa
    25981 aaatcatcgg atggggaatc gctaattcgg atcgccagcc cttgtcctat aagttatcag
    26041 ctgaccaatc gccatttttc gaagcaattc ctgtttcacg agaagaagtc aatcaagcag
    26101 aacagctcgc aaaaggaaca gaagcgggat ttgagttacg aatcctttgc gagcaagaac
    26161 gttcattctt agtggaagca gtagctcaaa atggccaatc atggatcatt gaaatgtaaa
    26221 taatgattaa cttataaaga taaggagtaa acgaatcgtg caaaaaaaag aaattgccgt
    26281 atttatcgat caaatcactc gtgaacgggc cactggcgat ttgcttattg tgggctgggc
    26341 aattgatgaa gtgaccaaag aaatccctac gataaaggta gaaaaagaaa atgtgattgc
    26401 tgaagcaaca catgtcgtaa gattggatat caatcattta tataatcttg atgttaagac
    26461 ccaaagcggt tttaaggtac gtttatcagg gaaaatgaga ggaaaagcca tcttagactt
    26521 ccaaacagcg agacatcaaa atggcatagc tgtgaaatta aacggtaaat acccttatga
    26581 tgacggcatt gaatcttcat gggaaagaaa aaaaagatta ctgaaaaaag ggataaatta
    26641 tgcaaggact catggcgtaa aaaaagcgat ccgtcgggtc aaattggaat tgaagccagg
    26701 atcgatcgac tatgcagagt ggatcagtcg tcatgagaaa ccagatttga aagagcaaag
    26761 gaaagaagca caaggatttg cgtaccgtcc attgatttcc atacttatgc ctgtctataa
    26821 cgttgaaatc aaatggctcg aaaaatgcat tgattcggta ctggatcaaa cgtatgatca
    26881 ttgggaacta tgtatcagtg atgatgcttc tactgatcca gctatccgaa agtgtctgga
    26941 atcctatcaa gcaaaagatg atagaatcaa agtcgttttc cgaaaagaaa atggacacat
    27001 cagtctggca actaattctg cattggaaat agcagaagga gaatttatag cactcttaga
    27061 taatgatgat gaattaccgc catttgcatt atatgaagtg gcaaaagtgc taaacgtaca
    27121 tccagaactg gatgtgatct acagtgacga agataaaatc gatgcagatg gcaatcgctt
    27181 tgatccgcat ttcaaagcag actggtcgcc tgatacattg atgggaaata attatatctc
    27241 tcacttaggc gtatatcgaa caagcattgt taaagaactt ggcggtttcc gtaaaggcta
    27301 tgaaggttct caagattatg atttggtcct tcgtgtgaca gaacaaatcc ctgcagatca
    27361 tatttaccac attgaccgag tcttgtatca ttggcggacg atcccaggat caactgcaag
    27421 taatggcgaa gccaaaagtt atatctatga ttccggagtg aaagcattga cagatgccct
    27481 gtctagaaga aacatcaaag gaagcgtacg tcctggcaga atttctggat tttatgagat
    27541 tgcttatgac gtcttgcaag aggatttggt cagtgtgatc attccaacga agaatggcta
    27601 tgaagatcta aaaacttgtg tggattcgat catcgaaaaa acgtcttatt caaattatga
    27661 aatcattatt gcggataacg gaagtacaga tccaaaaatg caagaattat ttgcagaata
    27721 caagcatcag ctgaaagacc gctttatcgt agaattgatt gacattccat tcaattattc
    27781 tcgaattaac aatttagcag cagaaaaagc aaacggcaaa tactttttat tcttgaataa
    27841 cgatacagaa gtgattgagc cagattggat gacggtgatg gtttcttatg cacagtttga
    27901 tcgaatcggc tgtgtaggag caaaactgtt ttatccagat gatacaacgc agcatgcagg
    27961 agtattatta ggaatcggtg gtgttgcagg gcatgcattg aataactatg atcgaacaca
    28021 ttgtggttat ttcggccgat tggtcattga cgtcaattac ttagcagtca ctgcagcttg
    28081 tatgatggtc aaggcagctg acttcaatgc tgttaacggg tttgatgaaa cattagaagt
    28141 agcattcaac gatgttgact tgtgcttgaa agtttatgaa ctgggtcgtt acaatgtcta
    28201 tgcacatcaa gcagaattgt accatttcga atctaaatca agaggttatg aagatactcc
    28261 agaaaaacaa agacgttttg ctggtgaaat caaaaaaatg caagataaat ggccagcata
    28321 tattgcgcat gatccatttt acaatgataa tttaacaaaa gaaggaatcg gcgacttttc
    28381 gttgagacca gattaaacta taataaaaag ctgttatgtt gtgattcgct cgcacataac
    28441 ggctttttat agttttttgt caaaaaaagg cagaaggtgc cgactcaaaa aaataagtcg
    28501 aggttgggac agaagtgttt aactccgaga aataagaaga aattcacgaa aattgctttt
    28561 caaatttttg tgaatttcgg cttatttaag aagaagttgc ttctgctccc accgtttatt
    28621 cgtttttaaa gaatgagaca aaagtgtttc ttacttttgt cccacgctct tattcatgct
    28681 cagagcgcca atagatacaa aatcatagcc aaagtttcac gaaccctagc tgtcaaagaa
    28741 tcgatatttt attttaatat aggctatttt aaaataaatg gtttaaggta ttcctctaca
    28801 aaagccactc tatcaattat catgggttta aaataagaag tgatggagat aaccagattg
    28861 ttcttagcgt caatataaag aacatttcca ctattaccaa ttgctgaata tatttcgttc
    28921 tcagaatcta atacccacca taaatagcca tatctcatat tttgtaagtc ttctaaagca
    28981 ctggttctag gtttgaacat ctcgtttatc cacatgggtg gtacgatttg ttttccttta
    29041 tacatccctt tatttaggca taatacacca atttttgcca gatcacttgc cgataaacac
    29101 aaaccatatc ctgccgtccc gatatttagt ggatcacaaa accagacatt ggttttagga
    29161 gacttatcca ttgtaaactg cttatgttct tcagctgttt cagcataata attgacatgg
    29221 tttggtatcc ctataggatc aaatagatac ttattggcaa aatcaacagt tgttagctta
    29281 cttgtctgat acaacaagcc agttaatatg tgtaaacaga cagtttgata gttgaattcg
    29341 ccggttatac cttttcttcc tcccaataaa tctagtgatg tttttgtcca atcttcactt
    29401 gaacagactt ttgtccatgg atcgccttta catttgtagg gtgctttcat tgttagcaag
    29461 tgcttgattg taatagcgta aatagttttc tccccgcgtt tcactttata ctctggaaaa
    29521 taatctaata ctttatcatc gatacttttg attaatcctt gctctaaagc aatgccaatc
    29581 agcaaagata caatactttt cgttgctgac atgatatgac aagtatcgtc ttttttataa
    29641 ccattccatt catctgtata aacttctacc ccatccttat atgcgacaat ttgacatata
    29701 tttggttgtc gaaaaccaat aaaatcatgc aactcttgtt tattcataag atattacctc
    29761 actttcttct ataagcataa tgtcattaaa aatcgatttc aattttttcg attcttcacg
    29821 taatacaggt attcttatgg actagacagc gctttgggaa gatggattct ctgaaaaata
    29881 taaaggttca ctttatgagt ggataaaaaa agcagcaaat acttcgactt ctttaattta
    29941 ccaacattag tgaaaatcga ttcatctgga gatttgtaat ttagagtcct tgtcttgatt
    30001 agaggtgtat aaagct
//
LOCUS       DADVXE010000030        29161 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.030, whole genome shotgun sequence.
ACCESSION   DADVXE010000030 DADVXE010000000
VERSION     DADVXE010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29161
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.030"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..2131)
                     /locus_tag="KB913_001451"
     CDS             complement(<1..2131)
                     /locus_tag="KB913_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6819819.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWM"
     gene            complement(2128..2832)
                     /locus_tag="KB913_001452"
     CDS             complement(2128..2832)
                     /locus_tag="KB913_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6819820.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(2844..5153)
                     /locus_tag="KB913_001453"
     CDS             complement(2844..5153)
                     /locus_tag="KB913_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBB6819821.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(5348..5812)
                     /locus_tag="KB913_001454"
     CDS             complement(5348..5812)
                     /locus_tag="KB913_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819822.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(5812..6438)
                     /locus_tag="KB913_001455"
     CDS             complement(5812..6438)
                     /locus_tag="KB913_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6819823.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(6445..6810)
                     /locus_tag="KB913_001456"
     CDS             complement(6445..6810)
                     /locus_tag="KB913_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBB6819824.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(6800..7138)
                     /locus_tag="KB913_001457"
     CDS             complement(6800..7138)
                     /locus_tag="KB913_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819825.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(7128..7454)
                     /locus_tag="KB913_001458"
     CDS             complement(7128..7454)
                     /locus_tag="KB913_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBB6819826.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(7435..7713)
                     /locus_tag="KB913_001459"
     CDS             complement(7435..7713)
                     /locus_tag="KB913_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBB6819827.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            complement(7715..9079)
                     /locus_tag="KB913_001460"
     CDS             complement(7715..9079)
                     /locus_tag="KB913_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBB6819828.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(9092..9661)
                     /locus_tag="KB913_001461"
     CDS             complement(9092..9661)
                     /locus_tag="KB913_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBB6819829.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(9633..10820)
                     /locus_tag="KB913_001462"
     CDS             complement(9633..10820)
                     /locus_tag="KB913_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6819830.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(10884..12611)
                     /locus_tag="KB913_001463"
     CDS             complement(10884..12611)
                     /locus_tag="KB913_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBB6819831.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(12608..13060)
                     /locus_tag="KB913_001464"
     CDS             complement(12608..13060)
                     /locus_tag="KB913_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBB6819832.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(13172..13552)
                     /locus_tag="KB913_001465"
     CDS             complement(13172..13552)
                     /locus_tag="KB913_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBB6819833.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(13549..13935)
                     /locus_tag="KB913_001466"
     CDS             complement(13549..13935)
                     /locus_tag="KB913_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819834.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(13937..14215)
                     /locus_tag="KB913_001467"
     CDS             complement(13937..14215)
                     /locus_tag="KB913_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819835.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            14263..14991
                     /locus_tag="KB913_001468"
     CDS             14263..14991
                     /locus_tag="KB913_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HBB6819836.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(15122..15598)
                     /locus_tag="KB913_001469"
     CDS             complement(15122..15598)
                     /locus_tag="KB913_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HBB6819837.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(15558..15905)
                     /locus_tag="KB913_001470"
     CDS             complement(15558..15905)
                     /locus_tag="KB913_001470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819838.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            complement(15892..16077)
                     /locus_tag="KB913_001471"
     CDS             complement(15892..16077)
                     /locus_tag="KB913_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819839.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(16078..16350)
                     /locus_tag="KB913_001472"
     CDS             complement(16078..16350)
                     /locus_tag="KB913_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBB6819840.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(16347..16550)
                     /locus_tag="KB913_001473"
     CDS             complement(16347..16550)
                     /locus_tag="KB913_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819841.1"
                     /translation="MVKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            16675..16887
                     /locus_tag="KB913_001474"
     CDS             16675..16887
                     /locus_tag="KB913_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819842.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            complement(16920..17114)
                     /locus_tag="KB913_001475"
     CDS             complement(16920..17114)
                     /locus_tag="KB913_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819843.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(17127..17309)
                     /locus_tag="KB913_001476"
     CDS             complement(17127..17309)
                     /locus_tag="KB913_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819844.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            complement(17306..17446)
                     /locus_tag="KB913_001477"
     CDS             complement(17306..17446)
                     /locus_tag="KB913_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819845.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            complement(17936..18301)
                     /locus_tag="KB913_001478"
     CDS             complement(17936..18301)
                     /locus_tag="KB913_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819846.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            complement(18341..18643)
                     /locus_tag="KB913_001479"
     CDS             complement(18341..18643)
                     /locus_tag="KB913_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBB6819847.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            complement(18643..18942)
                     /locus_tag="KB913_001480"
     CDS             complement(18643..18942)
                     /locus_tag="KB913_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819848.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(18935..19099)
                     /locus_tag="KB913_001481"
     CDS             complement(18935..19099)
                     /locus_tag="KB913_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819849.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            complement(19105..19374)
                     /locus_tag="KB913_001482"
     CDS             complement(19105..19374)
                     /locus_tag="KB913_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819850.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            complement(19386..20135)
                     /locus_tag="KB913_001483"
     CDS             complement(19386..20135)
                     /locus_tag="KB913_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6819851.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            complement(20132..20824)
                     /locus_tag="KB913_001484"
     CDS             complement(20132..20824)
                     /locus_tag="KB913_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819852.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            complement(20830..21501)
                     /locus_tag="KB913_001485"
     CDS             complement(20830..21501)
                     /locus_tag="KB913_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBB6819853.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            complement(21494..21835)
                     /locus_tag="KB913_001486"
     CDS             complement(21494..21835)
                     /locus_tag="KB913_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819854.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            complement(22013..22711)
                     /locus_tag="KB913_001487"
     CDS             complement(22013..22711)
                     /locus_tag="KB913_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBB6819855.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            22798..23268
                     /locus_tag="KB913_001488"
     CDS             22798..23268
                     /locus_tag="KB913_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819856.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            complement(23311..23490)
                     /locus_tag="KB913_001489"
     CDS             complement(23311..23490)
                     /locus_tag="KB913_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819857.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(23477..23815)
                     /locus_tag="KB913_001490"
     CDS             complement(23477..23815)
                     /locus_tag="KB913_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBB6819858.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            complement(23831..24034)
                     /locus_tag="KB913_001491"
     CDS             complement(23831..24034)
                     /locus_tag="KB913_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6819859.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            complement(24049..24825)
                     /locus_tag="KB913_001492"
     CDS             complement(24049..24825)
                     /locus_tag="KB913_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBB6819860.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            25124..25444
                     /locus_tag="KB913_001493"
     CDS             25124..25444
                     /locus_tag="KB913_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6819861.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            25462..25893
                     /locus_tag="KB913_001494"
     CDS             25462..25893
                     /locus_tag="KB913_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBB6819862.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            26023..26484
                     /locus_tag="KB913_001495"
     CDS             26023..26484
                     /locus_tag="KB913_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBB6819863.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            26518..27153
                     /locus_tag="KB913_001496"
     CDS             26518..27153
                     /locus_tag="KB913_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBB6819864.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            27266..27901
                     /locus_tag="KB913_001497"
     CDS             27266..27901
                     /locus_tag="KB913_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819865.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            28200..>29161
                     /locus_tag="KB913_001498"
     CDS             28200..>29161
                     /locus_tag="KB913_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6819866.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHT"
BASE COUNT         8584 a         5832 c         4558 g        10187 t
ORIGIN      
        1 ccatccattg tccatttgta aatgtccaaa taagcaatcg aacttgtgca tctaagctcg
       61 ttattggttc tttaatacct gcagcattaa ataagttttg aacataaact tttccatccc
      121 atgttgctgg accaacaaga ggatatgaag aaccatccca ctgaactaat ccgtatgctg
      181 gtccacctat ttgaacagta tcaggatcaa aagttcctcc tgtttcttgt tgaatgttcc
      241 ccaatattcc acatgcagat tgtttcgtaa atccgttatt acacaaaata tcgtatattc
      301 tccaagctct cttttctgca tctgttttta attcatcagg atacccacca ggtgtttctc
      361 ctccgccaga tggaccgcca ttttgtcctg gtatcacttc tttacctcta acagtaagtt
      421 ttccctgaat atctaaatca ccgaaataat atgcttttcc gtttcctaat aacacaaatc
      481 ctttttctgc agttggagaa attaaaatgt attttccatc gccatttgta cgtattacca
      541 aagaattttc ctcaagaggt gtaggtgtta cagcatttgg aaatggattt cctgctgaat
      601 ctgttgttcc gatcgttcca atggattctt ttctattcca gaattccata ccttttttgg
      661 ttagctccat gatttttttg ttttcattcc aaatttgaag cgtgcctttt acaagtttta
      721 acacatcacc ataagcatta aaggaagttt cgaatacttc tgcatttatt gttcctactt
      781 tgatgaagtc agcaacaatt tctccttttg atgtgatagc aataccgaac gggccattta
      841 ctccgttgtc tgaataacct aagccattta aattccaacg ccacactcgc tttgcattcg
      901 ccacatttgg agtatccatg ataagaatct ctgatggagc tttttctgga cgaaaaacga
      961 catgcccacc agaattacca gtgatccatg ccgtcgcatt caacacattt tgaactaacg
     1021 tttctgttcg attgtcgatt ttctttttca attcttgtgc ttgagtattt actgccgaag
     1081 tgtacagtga taaatcatta cctaaaacaa tatccttata tttcccaagc gttgggaaat
     1141 aagtgtattc gaccatacgc tcttttatct cgatatctag ctctttcgcc ctaacatgag
     1201 cgacatcacc aaagtgtaaa gacgctagct cttgatacat gtcaccgtat tcgagtgtgt
     1261 gttccaacgc caccatactg actgtatgag tagcttttgg ctcatggata cgatcattgt
     1321 caaataaggt tttgccccat ttgatcaatt catcaactgt tttacaatct ccgttttcac
     1381 gtttggcaat acgtcgattc tcgttggtta ctccatcaat ttctaaataa ccatattcga
     1441 taggttcttt gtcttcatca taatcgttat caggaacacc gccaaccaaa tacaaactat
     1501 tgacaattga ttcttcatca atttcttctt cgattgcttc taaattgatg ccaaaatcaa
     1561 tccgaaaacc attatctgat ccaatctgtt ttaccagttt caaatcatag ttatccatat
     1621 caagttccgc gctagtcacg ccagtcaaat tttgattacc gttatttgaa ccaatgattg
     1681 cttcaactgg cgcgacttgt cttgctgtaa attggtgcgt tgtccctaca ttcgaaagat
     1741 agttaaattt ttgatcaaat gccaaactgt ttttaagatt ggtcatgatc tgagacccat
     1801 tgccgttatc cgtaaacgac ttgacaataa agttcttatt ggccataaaa ccaatatgcc
     1861 gagctgttac agaaacggag gtcaaattct ttttgacatt ataaatttca aaatattgcc
     1921 atgatccatc tggtaccttc gcttttataa aatttccttt ttttaaataa gagcgatact
     1981 gtccgcttct tgaatagtta ccataaaaac gatattggcc attcagcaca cgattgattt
     2041 ctggcaaatc ttcccaatca actaacgacg ctccgttcac gctcaaatca tctggcattt
     2101 ttttataagc ataaataaat tcttgcgtca cagatacaca ctcctattcc aaaaccgcac
     2161 ttctttaaat tttccggata tttttacctg attccattca ggctgcaata ctggccaatc
     2221 accacgcgta aataaattca aaccttcttg tattgctttt ccaagctgag tatcaaccac
     2281 gattgttgca gctaacgtat taagtattgt taggctttta tcaccgacag cgatcgttat
     2341 atctcctccg ttcgattcta tttccagata gggatgtgca atttcgtcac catgatcaaa
     2401 aatatccata acactagaat gaaaaatttt aggtgcttca ccgatttttc ttttgagtgg
     2461 ctgacaacga aaagtaacat cgaatgtata aaagaagccc cactcgtttt cgaaagggac
     2521 ttctttatcc atgctgcaga tagcctctag atacttgtct ggatcattat gtgtgattaa
     2581 ttggctttta ccagtgagcc atcgtttgac ttctctcagt ttcgaatgtg gaatagtgat
     2641 cccttctatt tccaaatcaa aaggttcata gtcatcaaac gtctccgtca attctccgct
     2701 tcggccctga atcgtgtaag tttcgtatcg cttgttcggc ataatatctg gaagctctgc
     2761 ctcaatgatg caattcatat caattactgc attccgattt ttccaaataa aatttggttc
     2821 atctggattc ataaattgtc gactcaaata ggaacacctc ccaaatcacg aatagcctgt
     2881 ttgtttgctt tagcaaattt acgattcata cgatctaact cagatggatt gtttgcatcg
     2941 actttgccaa tgtgtatatg ctgttcaatg ctacctccag aaactcttcc actgatccct
     3001 ttgcgttttt cttcgtctga taatggagta actgtggttt taccattctt ggcagtcagt
     3061 aactcaggtc cagcttcacc aacaatcgct tgtccattga ttagatgacc gccttgtgct
     3121 aaataaggca gttttgaaat agaaaatgat tttccaccta caccaggaac ccattttggt
     3181 atctttatat tattcaatcc accaataaat ccattgatca atccaatcat ggcattaata
     3241 ggagctttcc ctacagcaac aataccatcg aaaatacctc caaaaatatc aactagacct
     3301 tgccatgctt ttgaccaatt ccctgtaaat actccagtga taaaatctag aaaaccactg
     3361 aaaattcgtt ttccagcatt ataaaaatta ttgaaatttg ctataacacc atcgaaaaat
     3421 ccaccaaaat aaccacttaa aaaattaaat atttcaacag ctacatctga aacacctttg
     3481 aagaaagaat tcactccatc atgaaaccat ttaacgttat tatatgccca aattagtcca
     3541 gtaactaatg cgccaatagc tataactgct aatgcaaacc agcctcccga cattccaaat
     3601 aaaccagcaa gtccttgcca aactcctata aaacttttaa cttccccaac gatttttgta
     3661 acagatccca taagtgaacc aagaacgatt agtactggtc caactgctgc cgctatacca
     3721 gcaattgtta tgatccaatt ctttgtatct tgatctagag acccccacca tttagagaat
     3781 tcctgtaata aggaagttgc tttttcaaaa aaaggcaaaa ggcttacttg gactgcttca
     3841 cctacgtcag ccattgctaa ttttgcattg ttcatagctt gatcggcttg atcaattggg
     3901 tcgagagtag catcgaatgt gtctcctaca gctcccccac tttctccagc agtttttgct
     3961 aaatcttcca ggttcaaagt acctctacga attgcatcgg ccattctagg accgccttta
     4021 gtcccgaata cttctgctgc tgcattgatg gcttctgttt cagaacctgc attttttacc
     4081 ttgtcttgta gttcttctag tccttgactt aaagattttc cgtctttcgc ataagccact
     4141 gttgctttag ataaactact taaagctgcg cttgaatcaa caccagattg ctcaaattgt
     4201 ccaagtaaag tgaccccttc accaaagctc aaccctaatt gtttaatttg tggtgcgcca
     4261 tcaattgctt tttgcatcaa gtcgtctaca gattgaccag tattctgcga tgttttcgtt
     4321 gttacatcaa ggacagaatt caaatcatca tattctagtc cataagcatc aatagcttgt
     4381 cgagcagata ttgctgattg cgaaacatct gtatcattga tttcagcgta ctgtaggaga
     4441 taattggttg aatcttccag ttttttatcc atgaatccaa attgtgtatt tacctcacca
     4501 atagcttccc caaccgtttg taaaggtaaa tgagtatttg aaccaacgtt tttgaaagac
     4561 tgtgaaagtc tatcagcttg atcacctgtt gctccggttt ttgtaatgat ggtatcaagt
     4621 gcctcgtcaa cttcaccaaa tgctgcaagt cctgctgctc ctgccgctac aataggcgcg
     4681 gttactccaa cagacatttt ttcaccaacg ccttttactt tctcacctgt ttcttcgatt
     4741 ttctggagtt tttttgctgt atcaacagaa acgtcacctt gttctttaag tgcatcgttc
     4801 gtctgttcta atgctgtacg aagtttattt tctccggttt cagaattgag taattgttta
     4861 taaagttttt ctgattcagc agaatattca ccggtttctt tgacagattt ttcatattcc
     4921 tctctcagca tttgagatcg ttgttcagcc aatcctaatt gtttttctaa tttttgttta
     4981 gccgctcgca atttttctgt ttgagttgca tccttgtcca tcgcagacac ttggtttttg
     5041 tactcggcag cggctaagtt catttctttg ttgatttctt tgattgtttt cgaataactg
     5101 acttcgccat tcgttttaaa attaagaacg acatcagatt ctttaccagc catttatctt
     5161 agcgctcctt tctaccacca aggcgattta tccatagtta cagattgagg tggttcaaaa
     5221 tcggtgtttt gttgtaacca ctgtaaataa gatttgagcc acaagttagg tgtagacttt
     5281 aaaaagaaac tctcactcca attcaataga gtgagagcaa cgtaaatata aaaactccaa
     5341 ggagttccta tctcttccga ttctttttgt ttttctttct ttttgcttgc gctttttgaa
     5401 agtcttgtgg cttcttggat ttttttaggt cttccacctg aaatgtctgg ctagcaaaaa
     5461 tttccataca ggtactataa gcagacaaca cctctccact cattcccaaa aatttgaaaa
     5521 tagtttctgg atcttcctct aaaccaccag tacgcagcat ggcataaatc aaggcacgca
     5581 tgatttttag atcactaggc gataagttag cagaagaaat ttgtccttct tttttagata
     5641 gcatggcgtt catatcagat tcaaattgcg aataatctcc accatacaca tctgctataa
     5701 attccatcgt ttgcatagta aatgaaatag ggaattctgc gccttgaata attacaacag
     5761 cagaattttt taagtcttca acgtgaattc cataatcaga taaccgagcc attaacccgc
     5821 acctccaact ttagccaatg ttttccactg ttcttcatcg tatacaggtt gagcaatgaa
     5881 tttattaaat aattctagag aagctccgtc tctatttgaa tcaaaacttg catacatcac
     5941 attattgtat ttcagtccga tggaaaccag atttgcagtt acatcgtcaa tttttgtttc
     6001 ttcctctgca gtggcatact cttcgtcaat cacattggat agttgtgtat taggatacca
     6061 aactgctttt ttaccgccat tttcaatatt tccaataaat ccaaaggcga agtacggaaa
     6121 ttctcgtgcg gtatttttgc taaacgttac tccgctttta gcaactaatc ctttgatttc
     6181 atccatcact tctatcggaa tacccacgtg atccaacgca agttcatgtt ttgtttctcg
     6241 cgacacacga cgaaacattt tgctggatgc ccatttttct aatgctgttc cattcccttt
     6301 gacaccgatt tttgtggcaa ttggcaatcg taaaacttca ctataagtcg gtgcagttcc
     6361 aacagaatct ggcgttgcca tcatcgcaat taaaatgtcg tccaatcctt caaaataaaa
     6421 agtatcttgt tttcccaatt aaaatcaccc ttcccataaa tcaagtattt ttctagtcat
     6481 aatttcttca attttttctt tgttttgttc atacgtacca cttgcaaaat gttgggcacg
     6541 ttgatttgtt gtgccatttt cggcaaagcg ccagtaaaag gccgtctctt caaattgaac
     6601 tttcacttga tcgttttcaa ctactacttt tatttgatcg cgcatatgtt tcttttttaa
     6661 gagcgactta ggaatattag gaagcaactg ctttagataa aagttagctg cttcttctaa
     6721 agattccaac gataattttt tcggatcaac ttttgaaagg tttcctaaat aatccgatat
     6781 ttcagaaaaa ccattcttat tacttggcat tttccacaca cctcacatat gtgtaatagt
     6841 tggttacggt atcgtcgttc tcatcacctt gtatacctgt aaaatctgaa tatggaatgc
     6901 cagcattttg cagcgcttgt tcaataacaa ctaaatcctg ttctgttcca agtgtaaaaa
     6961 aagagacttg gtaataaggt aattttttat agactttacc ggatgccatt tttttgctgt
     7021 tactcacatt tgagtacaca atgtatggat acatcgtccc taatctggct ttgtctctga
     7081 acactgctaa ctttgttgat ttcagcgctg ttttcaattc atcaaagcta atcgacataa
     7141 gctaaactca actccatttc tcttgcatcg ggattcgtat aaatgcgagt aatgttatac
     7201 gttacagaat caattttgag cgcacttaat ttctctgtga tggatttatc ccatctgact
     7261 ttaattcgtc tgacaacgtc tgtcttggct tgctgtgata aatatttttc ttgagaagtc
     7321 acaccgagtt cttcatagaa tattagacgc ttaaattcgt aaattgtagt tggacgatcg
     7381 tttccgtctg ttcctgtttt gatgtctagc aattcggctt tccatctgag attattagtc
     7441 tgtctcttcg gcattttgaa tcgctccttg cacgataaat ggcgtcatgg cattcatagc
     7501 tttgtcgagt tcatcctctg aaactctata ttcataggca atgccggcaa ccatcaaaat
     7561 aagatattct tgttggccac cagttgctgt tttgacataa tcttttgcca tatttaaata
     7621 aaaagagagc aaagaatcat ccatgccctc ttcaaaatga atatgtgatt tgaatttttc
     7681 ctctaaagac aattctttag tttgctcttc catcttaacc accaactggt tttgtaattt
     7741 cgtagcgata tactgccggt tcaaatggag aataaaccaa ttgaccatct agcaagttgt
     7801 aaatttggaa tccaatttga tttttaccag agaatttttc aacaagtttt tgaatttcca
     7861 aggcaccaat aacttcttga attttaaatg cagaaaaatc gccaaaatat aaaactggcg
     7921 tgtctggttc acccttttta tctgctgcat ctgtccaatc cacaggatag ccaactaatt
     7981 ggtaaccaat tccaccttct gcttgtgtga atggccgcaa caaaggaaat ccatcatctg
     8041 ttttcatttt ttcaatggca gtcaaagcag ctcgattaat aataaagcgt ccctttttca
     8101 tcacttctgt cactggtgta tttttaaatt cgattaatgc atcatataat ttttgcccag
     8161 cacctgaagc agttagatct aaaggttttt taaatgctac agcctttttg gctaatgcac
     8221 caggattttc atttccagcg tcatcaccat tgaacatata attgatttct ttacgcacat
     8281 aagctttttt caattcttcc acaacaatat cttcaactgg aacaccagac atttttaata
     8341 attttttagt tactgttgcc aaagcatcga attcggcagg attaagcaaa atttcatcaa
     8401 actgaatagc tgtttcagca atatcagttg aacgctcttt cttgtttaca ttcgcatctg
     8461 ctttcttcac aagaattgga tatttgacat ctcctgatgt tcgcaccact gttccgtatt
     8521 tacgaagtaa attttcttct tgagcataag taataacttc agatgcaatt acttctggga
     8581 cagtaactga accgttgcca gcttcaatcc ctaaagctcg agcttctgct tcagaaatat
     8641 ttccagctac aaaattagca aatgcttttc gtagttgttg atctttttgt ttcttggtca
     8701 tttttgcacg tgcctccaat ccgttcttaa ttgatccaag taatccatct cgttgctgtt
     8761 gagtaatcat tccagaacga ttttctgaac tatcttcact gtctgaatct tcttcttgat
     8821 cgttgtcttc accagaacgg ctttcgtctg aatccgtact attcgattga tcatctgtat
     8881 tgtcgtctgt ttcatcagtt ccagaatctg cgcctaattc gtctttaatt ccgttcaatt
     8941 catcaataac actgtcaatt tcttctttca cggcttctaa atctgcttcg cgtaattctc
     9001 ctgattcaac tttttcacgt aattcagtca atcgttgctc acgacgtgcc ttcatttttt
     9061 tcaataattc tttatccatg tatttttcct cctacgcttc tagcgcttga ttaatttttt
     9121 tgattaattt ttttctttct tcgacgtttt tttctaattc atcacgactt cttaatgcag
     9181 cttctgtatc ttcgtatgct ggcaaaggca caatagaaac ctcgtataat tccacttcat
     9241 ggattgttcg aagcattggt tcagaattgt agtcccacgt ttcttcagtc ggcacaaaac
     9301 caaaactaca ttggttgatg tctcctcgtt ccatagattt aactaagtcc cttgctaccg
     9361 ttgtgtccgg taaatcaact tcgaatttca aaccacgttc atcttcttca aggcgaaggg
     9421 ttccgctttt agtacgtcct agcacattgg accaatcgtg attgaacaaa caacgaacat
     9481 ccgaattact aattgccttt gagaatgcac caggaacaat cacttcgctt aagtcatccc
     9541 ataaaagtgt ttgactgttg aatacagcag cgtagccgct aatggtcctc gtatgagttt
     9601 cttcatcgga acgtgttgaa agattggtga tgtcaatcgt gcgaatttcc ttcttcttca
     9661 tttccatcac ctcctttcaa gtcttgatca ttcgttggta aggaatcatc tgttgcattt
     9721 ttctggccaa tcctagataa gtcatttgaa atatagatag cttgtgtttc tggagtattc
     9781 tgtttaggaa aaccaagcat ttctgccacg ttatctggac ttgtaatccc ggtacgaacg
     9841 atgttgtagc caatatttgt ttttgttgag taaggaacaa aatccaaaat attaattttc
     9901 cattccactc tatagccaga attaggcata aaaaaaagag cggtgtaatg ttcgctcttg
     9961 tttttcaata ttggtttgat tgctttgttg tgcagataca tcatcgcttt ttcaatatct
    10021 gtcttcatca gcgattgata cgtatcaaca ttgattccta gaaattttcc taagtctttt
    10081 ttgtaaacac ctaaataatt caaaattgcc gcgtcatcaa caggactttt taatgtctcg
    10141 atggaatatc cttttcccaa aggaatcatc ttaacagaat gatcactctc attttgcgtt
    10201 ccttccagtt gatccaatat agctttgaca atttttgttt gggcgctatt atttggattg
    10261 atgtgggcgt ctagtttaag catgaacgca agtaaaccgc ctttagtata tttgtccgtc
    10321 aaaacttttt cagcgctcag aacgccttct agagtgtttc ttgcaagatc aattattcca
    10381 gcacctttta atgaatcagt tccgatgttc ttaatgtgtc gaatcatttg accaggtatt
    10441 ttttgaccat tcatttcaaa ttcttcttga agtcgttcat tgattttagt tgttacaccg
    10501 tacgccaaat gaagctgatc cctatccgtt aatgggaatg tctcaccatt gatcaataaa
    10561 gtatttgttt ccaatttggt aaattcgaat cctgtcaaat aatcattggg actcttcaaa
    10621 atatttagta agtgatgatc tttgacttcg ttgccgtcgg gaccaataac aattggtgtg
    10681 gccaatgcca cctgattaga tatgtcttga actaattcat aaacatcaga agattccatg
    10741 atagatgaat ccgtcacata tctttgacca taacgtgtgt agtgtccaaa aatatcctcg
    10801 atatatccac gtttttccat aaaagaatag actgcattcg ataaccgatc acgtaatttc
    10861 aatttttttc accgcctttc tatttatcta tagatggaac ttaggtaatc atctaactca
    10921 tctgaatcaa tatctgtcat ttgattcatc gtttccttat gaccacacaa aaacgccacg
    10981 aacccatcaa tctttttctt tgattgacgt ttacttggcg ctttttgtcc attgatgtta
    11041 gtaattgcta caacgttcaa agtgcaataa aggaataatg gattatcaaa ttgaattcgt
    11101 ttctcataaa acaaccgttc gacatcgtca aaaggagcat tcaatacttt aggatattga
    11161 gcaacttcaa cgcattccaa tcctaagttt tctaatttct caacaagttt gtcactcatc
    11221 gctggatcat aattcacttg ctgaatatca tataaattca tgcagtcctc tatgtactgc
    11281 aaaatctgat cttgatcaat catttttccg tcgcaaaatt caacgaaacc ttgttcagcc
    11341 aaatcactgt aaggaacatt atcttctttt tctcgaaact ctaaatcttc attcggaata
    11401 aaataaagtt gctttacttt aagaaccgct ttaccatctt catcccatgt tgggaagttt
    11461 aaagatacac aggtcaaatc tcgtgtacgt gataaatcta aaccgatata acatggttcg
    11521 ccacttaaat caccaagttc ttgtgtggta actaaacatg gctctacttg atcctgttca
    11581 aagaaattat ccgcgccgtt cacaaataca tccaagtgtt tcgttagaaa ttcagctttg
    11641 gaatgagctg accgttgcgc tgttttaaat gccgattcta aagcagataa atcgactgat
    11701 attccccagt taggattgca catttcccag acttttctat ccgtccaatc ataattttta
    11761 tttggctcat agattagaac aaagtttgaa tcattatcat cacgtttcaa cacttctttt
    11821 gcttcgcgat atacacgcat tccaacagac gacgaacctt tcccagcagt tgagatatta
    11881 aacatcaatg gctgtggtaa agatatctga gcagacttaa aattgtcata ctgttccatt
    11941 ttctcctgtt tatgcaattc atcgttcaat acaaaatatg gattggatcc ctcgatatta
    12001 tcaatattct tggtttgaac aataaattta tttgagtaag ccatatcttc atgaatatag
    12061 tcataagtaa tactagaaac agttcccttt ggccccctaa atattttagt tccttcaagt
    12121 aggattggat tgtttaagat tgtaactgca aaaggtttgg cagcatattg cgcttgagca
    12181 aaatcagatg cgcaagcata gcaatcaact gataacgccc cttctccgta cattgcatat
    12241 cctaatgaac cgacagcaat caatgtttta ccattctttt ttggaatctg gacataagcc
    12301 tcacgagtaa cgcgtacaat ttggcctttt tcattttctt taacccaacc ataaatccaa
    12361 gaataaataa atttttccca gggttctaaa agaaacggtt ttcccaccat ttctcctttt
    12421 gtgtgaacaa taaatgattc tacccaatcc atcatttcat tcgcgcgatc tacatcaaac
    12481 caaatatctt ttcttttttt ccactgatac cagcgatcta ttgctaaacg aacggtctta
    12541 ggatacttct taggtttctt tcttacttct tttgcaaata aatcagcata atttacacca
    12601 ggttcaatca tttttcagca cctgccttct tacgccattt atttctgtgc gctgctagtt
    12661 catctactgg ctttacttct gggcgtgtaa tttcttcatc ttttcttgcg gtcgatcctc
    12721 cagcaattag tctaccagtt tttgctttgt ttgttaatcc taataaatct agagctttca
    12781 tcttcttatc tgcccaagtt tctacttgtt gtgccaatgg atgttttgat tgattagtag
    12841 ctcctgattt attcgtgaat ttttgcgtct ccggaaatcc tttttccttc cacaataaat
    12901 atttgtgttg gtaaatttca aaaatatcca agtatgattc gattaatgga tcaagagtga
    12961 tggtgtacaa atcagacaaa ttcattattt ctaagatacg agctttttca gcacttactt
    13021 tttcatcaat aatcgcttta cgttgcgctt tagtcgtcat ttttgtatac accccccttt
    13081 gttttttgaa aaatttgacc taacgatgcg cgtgactccc cgctacccta tctccccacg
    13141 cgaaaaaatt ttgaaaatga ataggggggc ttcaattgaa atacgaagga aaaacttttt
    13201 tgtcttccgt ttcgttttca acaattggat gacattttga acataatagc atgagattgt
    13261 ttggatcaag cttaagcagt tcgttgtctt tgattggtac aatgtgatgg acgtgtgctc
    13321 tctttccaaa tatgaactga ccacaccgct gacaatgacc accttctctt tcataaataa
    13381 attgacgcat atctttccat gcttgcgttc gatagaatgg tttgttctca tgatgataaa
    13441 cagactttgc ttgctgcttc ttcttgcgtg atctgcttga tctcttgtgt tcagtacagt
    13501 agataccctt tgctattttg ttcgtgcatc cgtcaaactg acagtatttc attctacttc
    13561 acgaataaga tttatgatat cgccttttgc acggatagca ccaggaatat caataccatg
    13621 tttcttagca tatgcacgca attcttttgc agtcatattg tccagttcat ccgtatcttc
    13681 agtggactga tcattagtag cttcgtctcc atcaaaatta gcagcagtgt ttccatcgct
    13741 atcaagaatt tcactgctat gagctatgag ttcgccattg acagcaacaa atgatttgcc
    13801 atcactcaaa attccttttt cttcttttac ttcaaaattt ggttcttgat ctttcggaac
    13861 aactactgtc cttttctttt ctgaatccca atactctgtt ccactaatgg atgttctaat
    13921 tttgatcatt gccattttaa ttctctcctt tgtaatttgt acggattact tttgcgccca
    13981 ttcgctcata ccattcaatc gtttcctgca gattgggtag agtgtgtgac aataaagaaa
    14041 taactaacgt attcattcca gttctgtaat catcattctc cacttgcaca tgtgcatgat
    14101 taccattcca attttctctg tacggactat tctctgcttc aattgctttc ttataaactt
    14161 tagccaaact tgattctact tcaatactaa gtaccgcttc atgaaaatca ttcatttgtt
    14221 tactctccta tcagatattt tgtggtatga tttataaaaa agatgcgagg tgttttaatg
    14281 cttcaagaag ttaatattaa gtatcgtgat cgtcaaaata cagagacaat ttatttgcca
    14341 aatagttgtc cgcattgcgg aaatataatg actccgtatg tgtattttgg ggtttcatca
    14401 tatagtgcgt tcgataatga tagaatcttt ggcgtattag tacagtgtat aaatgatgag
    14461 tgcaacaaat tttatagttt acaatttata aatacgttta atgaagatga aggatattct
    14521 gaaaatattt taattaaaga ttattaccgt ccgccgatta aaatagattt accagaaaat
    14581 attgaaaaag tttctcctac atttgttgat atttatactc aagccacaca agctaaatct
    14641 gagcaattgg aacaaattgc tggagttggt tatagaaaag ctctagaatt tctaattaaa
    14701 gattatgcaa tatctaaaaa ttcagaggat gaagataaaa taaaaaaaat gttattaggt
    14761 aaaacaattg aaaattattt gaatgatttt cctaaactcc aaagattagc caaagctgct
    14821 acttggattg gtaatgatga aacgcactat gttcgtagac atactaataa agatgttcat
    14881 gatatggatg catttattaa atcagcagcg caatttatcg cggctgatta tgatgctgat
    14941 ttagctgatc aatttataaa tggaaataac tttatgccaa ctactaatta aaagaataaa
    15001 agagccacag ataccaatta ataaaacggt tgggatatct tggctctttc atattttttt
    15061 gacactaata gaatatcatg ctgctaacaa tgtttacgaa catttagtga acagtgtaat
    15121 tttagaataa agagagttgt tctttgtact tctcgctatt gtaaaaatca atttcgtttt
    15181 cttttttcaa tcggtcagct tgtctgtgtt catactcatc taaaaagttc aatgtctttc
    15241 taatttctgc atgtcgctgt ctgacatacg atgagctata cccaacagat tcagcaatat
    15301 cttctaagct catttgatca acatatttca tcttaacaat ttgattatcg ataccagaaa
    15361 agctatctat cagcaataac atttcttctt tttgctcgat caacaattcc aattcatttt
    15421 ctatcttttg gatattctct tctaaagaag aagttctcga attcttttcg atgcggacgt
    15481 ttgctaaatc accacagacc catcgattca attcaagctt acttttatta agattccact
    15541 ttaagtaaag aatctgctca tctagttctt ggtaatcttt taaccaatga aatctcacaa
    15601 acgccacccc ttatggtaga atagtattgc gctgctatct cgaaaggggt agctttttta
    15661 ttttttctta gccgttccat tctggattgc cttttgttcc aaacgtcgtt ttttcttctt
    15721 aatctttgat tttgtttttc ccatacaatt ctcctttccg aaaacacatt ttgttcgatt
    15781 tttaatacta aataaaagtt ggccagaatt tttcgttcgt ctttactcat ctttttttga
    15841 ataagattac tagcataaaa atagttagta ccacgaaaat gaacaggtaa atcaattacg
    15901 ttcaccttct tcatgccagt tatcagccac tagaatcttt gcgttagtgc cgccaccgtt
    15961 ttcttttttg tatttttcaa atgctttata agcagctgtt tttgatttat agatttttcc
    16021 ggaaccgact gggaacatcc atgtgccctc tgtgatagct aagatgtata ctttcattta
    16081 attcacccct ttaatcccca acactacata tccggacttc tgcatgtaat cagtaatata
    16141 agtgatctct gctttgtatg agtcaccagt gtaactaaat gttggtctcg ttagtccagg
    16201 taattcatgt ttaatgtatt ttttatattc acgtagtatt aactgatcac caactttgaa
    16261 gtcacgatca ttcttgcgga tctcgaattg tttgcgtccg ctcgtcactg cttcaaaata
    16321 ttctggtagt atttttagtt cgtggatcat tctgtttcct ccttcaaaat tcgctcatca
    16381 tcaaaaagtg aatctccaca aaatccttct cccaaatatt tatcgttcat gtataagtca
    16441 accaaatatt tgtgatctgc ttctcgatat tcattaatat taacgatctt tattttgtaa
    16501 acattacctt cgtcgctcac tatcttgaat tgttctctga ctttcaccac cgttcctcct
    16561 ctttttgaaa aaattttagt gtttttgtaa gaccccctaa atcagctttt ttatttgata
    16621 taatacttgt atcgattaat caaatcgaaa ttaaatttaa aaaggtgatt tatcatgaat
    16681 atcaacaatt tagtaaaact cgttgaacaa cgttttaaag aatcaggatt agaacaatta
    16741 aaaaaagata attctccaga attattttct aattttaccg aagacgacat tcctactctt
    16801 aaacaattaa aatattattc tgattattgg acgcaaactc gtgagaatga attaaattta
    16861 gaaaaactca ttattaaaaa gaaatagcaa ctccagccca cacggctggt tttttagttt
    16921 caacttccct ccttacgggt caaaatcatc ggttccggca taatctgatc atcctttagc
    16981 aacaaatcag gatatttttt ccttagcttc ttattgttcg tgtaagtttt caatagccat
    17041 tggttggctt cgcttttgct ttctccagaa aaataaattt tccctgtttg gatgcctgca
    17101 agttgaatca tcattttcac ctcaaatcaa attttttctg ctagatggag caaaagcaat
    17161 ccgacatcaa gaatcttttg acccattatt tcagctactt tgctcggctt aactccttga
    17221 gaaaagagca agcgtgcttg ctctatctct tcgtgagtcc aaataaattt ggcttcctca
    17281 aggataatta ctggatcagt tgctctcatt gttcctctgg aaaaatgatg tcattcttat
    17341 gcttggacca ggtatctgca tatggaacaa agtattgtct agctaattcg atttgatcaa
    17401 ttaaagcagt ttctgataat tcatggtctg cagcaatttc attcatacta tcgccttcat
    17461 ctaaacagat aagaccgttg acgttatcga tttttacatt tgtgactgct tgactttctc
    17521 cacgctcata atattctaca gttgatactg atacatcagc ttcggagttt aattgcagaa
    17581 tctgttactg ccgggataat ttaatattct tttcataatt cacctttttt cctactgaca
    17641 tcgaatattt ttcatgttat gattagccgt gaaaggagag ctatattatg tgtttacaca
    17701 tgatgtcctt agctcattcg gttctttgga agcttttttg gaaataactc tcaggttctt
    17761 gacgcaaatc tcatttattc tttgaaacaa aaaacttcca ttttccgaga gctttggatc
    17821 acttcaaaag agatttgcat ttatatttct gtgaccttga gtcgcgtaaa gaaccttaca
    17881 gcaatggcgg caattccact ttcaggaaac cgcctttttt cattgatatt ggtggttagc
    17941 ggactaccca ttttctttcg gcagtgccaa accacaaatg atctgtgttg atgtttaggt
    18001 agttgtatac cagataagct aaatccaaag tgcctgcatc ttcaagacga caatattcca
    18061 aaaattctcc catagctgga cataaaaatc ctggagctat catatcccaa cagttaatag
    18121 tgcaaagaaa ttcgtttagc ttctgaacgt tttctttggt ttcacgaatt acaacatact
    18181 ccaattcttc tccgctggca gagcattcca aaacttcaaa ttgattaaga aatggtagaa
    18241 catatgcttc aaacatcaac attccatctt tctgtttttg cacttgtttt gcatcaatca
    18301 tgtctatcct cctattcagt tatttcttcc attaatggaa ttatttcagg tcactggact
    18361 taacgaaaac accattgacc atctttccag tccgaccttt gatttcgtca taagcaaaat
    18421 ccaagcactc gtataaatcc atatcatttt gcattgccaa gatgatcaag gttactacta
    18481 catcgccaat tccgtctctt aaaccatgtt catcttttct agctagagaa gcggcaactt
    18541 ccccgatttc ttcgaccgtt tttaacattt gcttgctgaa atccgcttga tccaatccct
    18601 tatcttttgc ccactgctct actttcgcga ttagttcgtc cattatttct cctccacata
    18661 cctaaactgt cttccttttg aatcaatcca taagctccta gctctatccc aaataatatt
    18721 tttgctcaga ccagtaattt cagataactg tttagcggta cccgttacta gaattcgatc
    18781 accatgccag attgcaatct ttctcggcgt tctccgtttg ggcttttcag tccacattga
    18841 tttaccgagc ttttggactt ctgcaactat ttttttatct tcctgccaat cttctgaata
    18901 agtcaattcg ataattcgct gcattgccgc tttcttatcc atcccgacat tctcctttca
    18961 gtaatttgag tacttgatca agtgcgctct cacgtccgcc atgaaatgtg ttgagccact
    19021 tgtcttcgta cgacacactt tgtcttaaag cttcttgatg cattaattcg atctgtgctg
    19081 taaatgtctt taggtccatc ttgtttacac ctgctcaagt tcattaagat gtttttgcaa
    19141 gcctttaaca caatcaatga atagtaattt ggtatatgct aaatttctta attgcgttcc
    19201 atcgatatag agtgcgaaat agtatctgag tttactccaa ctcgaacgat cattcttaat
    19261 tccttcaatt ccagcttctt cgagttgatc atatacgtct ctcaggacgt ctaattcctc
    19321 gcccttttta taattcgcta tttcattaat tagttctaga taatcgatct tcatttttcc
    19381 acctcttaga atggtgcttt tgattgtcta ttagctcgtt ctagcgcttt tttcttgaga
    19441 taggcttctt ggtcgattgc ccattcagga agcttctctc gtcttcctgt gcgcttgtat
    19501 ccactgcttg cgttcttagg ttcacttttt tctttccttg cccaacttcg aatagttgcc
    19561 aaatagtttt tataagtctt accagatgat tcacaatact ctgacagtcg ttcgattcgc
    19621 tcttggtaat cattagggaa ttctgttttg agtttctcca tctgctcatc tgacaaaaga
    19681 acatttttat actctccgta tttatgacgg acgggcttag ccttcgattt tttcgaaggc
    19741 ggtaactctc ttatatattc ttttgtatta ttaaatgtat tattaataga tgtattatta
    19801 tctttgactt tttcgtcaat aggggtattg cgtttttcgt caatagggta ttgattaatt
    19861 cgtaggtacc tattgattat ttgattggta ccctctttgt aaatgatttc ccgattcaag
    19921 tatccaaact taatcaaatc acttacccat cgcgatatgg tctctttatt cacaccatat
    19981 aaatctgcaa agtactcatt gcctgcccaa caaaagcctc tttcattaca caaggccgtt
    20041 atctctccgt ataacaactt agtatttggt ttaagtcttt tgtcgtacct tacgttggct
    20101 ggtataatcg cataataact tcgatgttct gtcatttttc ccctccaata tttaactttt
    20161 tgattgtttt ctggtttaat ttgatccctt tgatttgata tttatttttg aaattaatca
    20221 cacctatttt gtgcttctct gtgtgatgga ttctgcagag tgctgcaaat gtgtactctg
    20281 catgatcaac ttctttgcgc tttcgtcttc ctagcgcttt gtcaaagtga tcgatgtcag
    20341 ctcctgtttt gccacagatg cagcagactc tttttgtgat gcatttgtag aagtaatatt
    20401 cttgattcgc aggtaaaatc tcatagcctt ctttgaaagg aatatgatgt tcaaagatga
    20461 aatctaagat gatatttgct aagacattgg catcactcac agttgtattc gattcgtctt
    20521 tcaggcttat tttgcgccct gtgacacctt caaaacgaaa gtagaagaat tccttccaga
    20581 agtccgttgg catgcctgta tcgataaaaa tatcgcctat cagcgcatag atgaagtttc
    20641 gttgctgtac ggtgaaacgt ctaggatcaa taaaacgaat ttcaatgact cgatcaccat
    20701 cgtagccgtc atacatcgtc tttagtcgat caatgttcac ttcctcattg atggttgcgc
    20761 ttatgtcttt tcctttgaac tttttcagaa ccgctgaata tgaatcgatt aatggtttaa
    20821 acactcatat cacttcttat ctaattcttt tctcttagct gctattgctc gctccatcaa
    20881 ggcacattgc tcatagctta actgttcaat agtttcaacg ttatcagcta agagccctaa
    20941 tttatctgtc tgctcattaa catattcgat taaggttttg gtcatatctt tacccatctg
    21001 ctcattgaaa gcttctagaa tcgtctctag catgtttaat ttctttgtat cgattctagg
    21061 tggtgttgga atatcttccc cttgaaatac atataatccc agtccgtgta gagccaatgc
    21121 tttcacaaag catcgcttca atgagttatt gatttgcatt gcatttggtt taacaactgg
    21181 ttggtttcga taatctaaaa caggaaataa ttcggtttcc gtgtgtcctt taaccgttac
    21241 tgagacagat acataagtcc cagtttcatc cataagaaaa ggtttatatt cctcaacaag
    21301 aaagtcttga tgagttccag aaacaaccct gtagtgtttg tactcattaa tagttaccgt
    21361 tgcctgtgga tcattctttt tcataatctc ccacgcgtga gcccaagata aataatcaaa
    21421 atttcctttt ttcttgagaa ttttatttaa cttacgacta aaaagttttt caaagttcgt
    21481 tgtccctttg atttcactca tcaaattctg cctccatttc agcaatgtat ttcttacctg
    21541 gtccgtaata agagatatca atcaagttat ctctgtcgta ctcttctagc gcatcaatca
    21601 agccatcttc gatgacgtaa atatattcag gtttattcga atgcttcgat agatggataa
    21661 gataaacatg atcccaaata gttacatggt tgcctaaatc atcttgatcc caagctagtt
    21721 cttcattcgt caaaagattt cgtctgattt ttcgaccact tgtttcctca attttcggct
    21781 tgccccaatc aggatcaatc aaatattgat ctagagtgga aagttctttt tccatatgct
    21841 aaaatctcct tatgatgtgt tttctttgtg actctttgct tgccggcgga gtcacttttt
    21901 tatttgttgc catgcttttt gcttgtcaat atgttgttgg cttaggatga ttggtttata
    21961 gtatttccac cagcaattag caattgccgt ccctattctt agcgcttcag ctctattcat
    22021 tgtcatcacc aaaaagtctc tgttgtctgt tcagttgatc aatttccata cggatcgcag
    22081 tttctggcaa ccacatttca ataaatgaaa cagcatcatc gaatctctta cgaggtaact
    22141 cgccatatct tgggattgaa aaggtacgtt taaattcaga ccaaaatttt gagaatactt
    22201 ttttgctgat ttcttcataa gctcggcttt cttttccccc tagaactccc ataactttca
    22261 tatttccttt ttgcttaatt tcaaactctt gttgtccgct aattcgcata gtatctttaa
    22321 gcatggaaac atctttttta acatctttca tttcttctaa ttgatagatc atcatatctt
    22381 caattgtttg aggaacagta ttcttgcgaa taacatcttc catttcgttg aatgcttcaa
    22441 tgtatttttg tttgaagtag atagctttct ttcctgtaaa ccccatagcc agcaagaaaa
    22501 atccatctct actaatgaag aaaactcgtc gatttctgcc atatgaatct ggttcattac
    22561 cttctacaaa catctgtcca aaattggaca catctttttt tagtgcatca atatctctta
    22621 aaacatgttg atgttttttc tcgaagcttt ctgccacttg taagctcgta gtcacagctt
    22681 ctttattttt caaaattact aattcttgca ttatttcttc tctccttttt ggtataattt
    22741 agttaaaaac tggtggtgtt tattttgaat ttttttcact taacaatttt tcaatggatg
    22801 tcaataataa gttttatatt gagtacgttt ttaacaggga taaaaataaa aggaatgcgc
    22861 cctcaactag aagttgaact taatgcttct tacttcgctg cagatatgat ttatacaaaa
    22921 gtaatcattt ctaactattc aacagaacca gctatgttag ttaatttaga actttcatcc
    22981 gctaacttaa accgcagatg gtcagctact ccatttaaga aattaattgc taaaggagga
    23041 tcagtcgatg ataatagaat atactctgaa gctgtaccgc taaatattcc tcctaaaagt
    23101 gctatatctt gttaccttgc atttgaagta gggaaaatta attttaataa actccttaat
    23161 caccaaacaa aaatgatatt tactctaaat agaacccaaa tccacaaaat tgttgatatc
    23221 aaaaatacaa acttcccaat agagaaatta gtgaaagaat taaactgagt aatagtaata
    23281 tacattctag tttctctttt ctattcattt ttagtcagcc ccctcggttg gctttttcgc
    23341 tctgtactca gcttcagctt catcaagccc cataaaaatc caaaccatgt aaacaatcgt
    23401 tcctatcaac gcttgcctgc ttccccaaag tcctaaagcg tagatgatta gcggtgcgct
    23461 gaacactagc gctctattaa attttcccat ccgcttgcct ccttaagatt tccgaaaaat
    23521 ttgtttctaa aaattcaagt gttttacttc ttaaaaatag atatgtgtct cttccttcaa
    23581 ctggataata gacaaatcca tttttgtttt tctcgatatc gataatattt ctatatcttg
    23641 ggttctttaa aactctagaa gtaaaccaat catattttct gttaatccgt tctagcactt
    23701 ctggcaacgt catccatcta ccagtatcat cagctttttt taactcctca taatccactt
    23761 gggagataat tacatagcct tctggaattg ggatttttgc ttctagatat tgcattagct
    23821 gttcctccct ttacaattcg tacatagtga taatcgaatc tataattctg tttgcttctg
    23881 cagaagtctt tttaccgttt aaaattaaag ataagtagct tttgctaatt ccaaatcttt
    23941 cagcaagcat ggtgtaagtt aagaactttg aactttcgac atattctttg attttttctc
    24001 tatctcgttg agtgatttct gcaatgtcag tcatactaaa actcctttct aaccaatttc
    24061 ctctaaatcc atttgagggt aatatccttc tttttttagt aattcgtaga taaatagacg
    24121 ccctttctgt gtccatttgg tattcattac aattttagtg ccaccatcgg ctttcgggat
    24181 ctcagttgta tgagattttg tgtatccttg gttcatgtgt tttttgcaca ataaccattg
    24241 gttaccgact tttttctgaa tacctagttt atgaagtaat ttattcatct gttgtggaga
    24301 catcccataa tctgctgcaa tctgactaat tgttactgaa tctgtagaag ataatatgct
    24361 atctaaatag gagattttag gttcgtactc tgcaatcttt tgttctgcga ttaatcttcc
    24421 agttctttct tcttttagtt gagttgctaa ttgaatgatt gtatctggat taagcaaagc
    24481 ttcttctact ttttctggag ttagataacc tccatgtttt ctaattgctg gcaacacttc
    24541 acttgttacc caacgtttaa attttttggc agagggaagt tttgatttta agattaaact
    24601 gtacaaacca gattcgttga tgattgtcat ctctcttgat tgacctgagg tcgtgattcg
    24661 cgaccccatc ttatcttcca aatctacatg ccgcgacaaa gcatctttag tgtttgaata
    24721 acccaaaaca ctcgcaacgt ctttgcctac aaaatatggt tcatcattta ctaaaattgt
    24781 ccgaacttcg ttttgttcga aattaaaaat ttgcggtgtg ttcatatttc tcattccttt
    24841 cttttatatt cgtaaacaaa tttaacaact tttttctaaa ttcaattgac agtatctgag
    24901 taatactcta tactaagagc ataattaaat aagacataaa aacattgatt ttaaagcttt
    24961 cttggcggtc tgcatttaca tatcaatagt gttttttgtt gtctttttag ttgttaaatc
    25021 tgtttacaag atatagtata gctcattact cagaattagt caaattattt ctgcgtattt
    25081 ttctaaactt tttttgtaaa catttagaaa ggttgtttta tcgatgaata cctatgaaat
    25141 aataaaagac ttggcgaaga ggaaaaagat atctatacgg cagttagaaa ttaattttgg
    25201 atattctaac ggttatctag caaagtggaa aaataatact cctaattcag atgaattaag
    25261 tcggattgct gactatttcg atgtctctgt agactacctt ctaggtagag aagaaagaga
    25321 aacccctaaa catgtggatt tatcagaaga cgatactgtt ttttcttttg atggaaaaga
    25381 aatatctaag gagacaatgc gtaaagcgat tgcaattgct aaagctttag aggaaaatga
    25441 atagttggag tgatggtttg tatgtatttg aaattgaaag aaatgttgag cgaatacaat
    25501 ttgaaagtag tttatatgga gatgaaagag cctggtttct actatccaaa acccagaatc
    25561 atttttttga atgaaaatct atacggtgaa actgcagaag cctttcattt atctcatgaa
    25621 cttgcacatt tcagcgcctc tcattttgaa ttttcagttt tgtacgatac ttctacaact
    25681 tttcactcaa aatttgaaac agaagcagat aaaatagcta ttctaatttt attaaatatc
    25741 tatattgaga acgaactgac tgatgaatct cagtttaatc tcgaaaaatt tatggagtat
    25801 tattctattc agaataagct cagatacact tgttatgctg tctgccaatg ctattttaag
    25861 aaaaaatatt cttacgcaag gcaatatgta tgaatacatc aagaattatt aaaaaaaccg
    25921 atttcagcaa aacattaaaa aagcccgtgc tgcaacacgg gctctttcct catatatgag
    25981 cttctacaaa aaaaatcata tcacagaaat gaggaagaaa aaatggaaaa agagatttta
    26041 ataaaatctc caggaaaaac cttgattaaa gtaactgatg attctatttc aattattaga
    26101 aaaggattta taaatttagt taatcaaggt attaaaggag aaaaaactat cccctttaaa
    26161 aatatatcag ccgtacaatt aaaaaaacca ggtatgagta atggttatat acaatttacc
    26221 ttgctaggcg gaaacgaaag tcgcggaggt atattagcgg ccacgaaaga tgaaaacacc
    26281 gttatgttta caaaaaaata ttggaatgaa atggaaaatt taaaaaaata tatagagaag
    26341 caacaatcta tattagataa taattccaaa gaaacacaaa tttcaagtgc agatgaaatt
    26401 aaaaagtata aagagttgtt agatgaaggg attattaatc aagaagaatt cgattttaag
    26461 aaaaaagaat tgcttggttt ataatattca atatcaaaag agaaagagga tctattaatg
    26521 gacggtatat ttggttttac tggtattgtt ttatttatta taggtttaat catgttaatt
    26581 gtaagattta tcaaaaaaac aaataagaaa acacctatga ttctccttat tatcgggatt
    26641 atttttacta ccgtaggttt ctcgctttcc tcatcaaacg aggcaaatga caataacaaa
    26701 caggaaagct catcatctga tactcaaact actacatcta acagcagcaa taaaagccta
    26761 actcaatttg aagaattttt agagacaaat aatcatgact ggggtgcttt cttagatagt
    26821 tattattcta ttactccagc tactgagcaa aatacagctt ttactaaata tattagtggt
    26881 aaaacatata cttttgaagg aactgttatc gaatcaatga ctactagaat agccattata
    26941 gcagacaaag agtacgatga taaaagttgg aatgatattt ctgcaacacc taaagtttca
    27001 tatgtaattt ttgcgaagga cttaaacaat gctgatacct ttacaaaggg cgataaagta
    27061 acttttacag gagaaattag ttcaagagga tcgaacatag aaaaatccta tgctcaatgg
    27121 gatatgatta atagtaaagt aagtaaaaaa taaatgaacc acgccccact aagagttaga
    27181 ttgtgcacaa taataaaacc tatacaaaag agtgccatca ggagtcacaa tgcttgtaaa
    27241 ggaaatgaca aaataggagg taactatgga taatagcaat gaaaaactaa ccaaaaaaga
    27301 atatcttgaa ttaatagttg aaggcggtat tggagcaatt ccttatattg gtggcgttgt
    27361 gcagtcactt tattttgggt ctaaaaacga gaagcgtttc aaacgcatcg agaaattcta
    27421 caaaaattta aacgaatcat tagaaaacat tcgcgatcaa attccagaag atgttttcaa
    27481 cttagagaac aaggaccaac tcattggaat attcgaaggg ataaatgacg aggtagaaaa
    27541 atcaaaggca caaaataaaa tagatatgta taaaaatctt tataagaatt gtttacttcg
    27601 aattaacaac gcttcatggg ataacgagga gtattatctt cttgtactga atcaattaac
    27661 atcgattgag attcaattgt tagcatgctt aatgagtcgt ggaaacgaaa atttcactgg
    27721 aaatatcagc atgtctggct attcacaaga gctaatagat ggtagcttaa atagattatc
    27781 tgattttggt ctgttagaaa aaacgattag ctccatagta ttaggtgatg tcggcaaaca
    27841 aaatatgggc tacaaaatat ctcatttagg aattcaattt attaactcaa ctcttactta
    27901 agttttcttt ctaatatgac atctagacct atcagcaatg caacaataaa aaaccagaca
    27961 taccaataat caacaaataa tctaaactct ggaagttcag ttattctttt aaaaatcact
    28021 ttaatcataa taaacacctc tgattggatg atctaataca catccaatta taccattaaa
    28081 acgacaaata gcacatcctt gcgccggcaa gcaaaaagga tgtgcaaaaa ataataaaac
    28141 ccaaacaatg ggcttcttta tagttcctat tgtatcagag aaagagagct gattcaatta
    28201 tggcaagatt agtcaaacgt ggaaatagtt ggcaatacga aatttcatac aaaaaagatg
    28261 acggaaaata cacgaagata agaaaatcag gatttaagac aaaaggagaa gcaaaagatg
    28321 ccgccaacga attagaatat aacttgaaca aaggccttaa aggggatcgc aaaaatctat
    28381 tattatcaga ttactttgag gattggatgc aactttataa agaaggaaca gtatctccta
    28441 tcacttatag aaaatacgaa gatacgttaa tgaacataaa gaaatatatg ccagcggtat
    28501 tgatttctga tttagataga gtgggatatc aacgcttttt aaataagtat gctaaagacc
    28561 atgtaaaatc taccgttatt aagtttaata accatattag agcgtcgttg aaagatgccg
    28621 tagaagaagg attaattccg tttgatccaa ctagaaaagc agtaatcaaa ggaaaagatt
    28681 cattgaagcc aaaagaagat aaatatttag attatgatca atttaaatct ttaatgaaac
    28741 tcgtagaaga aaacctttct gcgcagtact cttctcctat gctcgtgtta gttgctggtg
    28801 ccactggaat gcgatttgct gaacttctag gattaacatg ggaagatatc gatttcgaag
    28861 atcaaatcat cactattaat aaaacatgga attataaatt aaatgaatgg ggaaaaacaa
    28921 aaaacgaaac ttcaaatagg aaaatttcca ttgataaaca tacgattgat ctcttaaaaa
    28981 agtttaaaat caatcaaaaa gaattattcg agaattttga aatcaaaaac cctcataatt
    29041 ttgttttttt caacttaaaa aatggattag tttcatcaaa cgccgtcagc aaatatttgc
    29101 gcaaaaaatt aaaagaatta gggattgaaa agcaatttac tttgcatgga ctaaggcata
    29161 c
//
LOCUS       DADVXE010000031        29097 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.031, whole genome shotgun sequence.
ACCESSION   DADVXE010000031 DADVXE010000000
VERSION     DADVXE010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.031"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            279..1064
                     /locus_tag="KB913_001499"
     CDS             279..1064
                     /locus_tag="KB913_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6819867.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            1077..1928
                     /locus_tag="KB913_001500"
     CDS             1077..1928
                     /locus_tag="KB913_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBB6819868.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(2052..2504)
                     /locus_tag="KB913_001501"
     CDS             complement(2052..2504)
                     /locus_tag="KB913_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6819869.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(2969..3337)
                     /locus_tag="KB913_001502"
     CDS             complement(2969..3337)
                     /locus_tag="KB913_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBB6819870.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            3487..3969
                     /locus_tag="KB913_001503"
     CDS             3487..3969
                     /locus_tag="KB913_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBB6819871.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            4006..5016
                     /locus_tag="KB913_001504"
     CDS             4006..5016
                     /locus_tag="KB913_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBB6819872.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(5131..5844)
                     /locus_tag="KB913_001505"
     CDS             complement(5131..5844)
                     /locus_tag="KB913_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819873.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(6034..6624)
                     /locus_tag="KB913_001506"
     CDS             complement(6034..6624)
                     /locus_tag="KB913_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBB6819874.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            7108..7335
                     /locus_tag="KB913_001507"
     CDS             7108..7335
                     /locus_tag="KB913_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBB6819875.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            7351..8517
                     /locus_tag="KB913_001508"
     CDS             7351..8517
                     /locus_tag="KB913_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBB6819876.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            8751..9794
                     /gene="hrcA"
                     /locus_tag="KB913_001509"
     CDS             8751..9794
                     /gene="hrcA"
                     /locus_tag="KB913_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBB6819877.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            9888..10451
                     /gene="grpE"
                     /locus_tag="KB913_001510"
     CDS             9888..10451
                     /gene="grpE"
                     /locus_tag="KB913_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBB6819878.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            10502..12331
                     /gene="dnaK"
                     /locus_tag="KB913_001511"
     CDS             10502..12331
                     /gene="dnaK"
                     /locus_tag="KB913_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBB6819879.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            12482..13648
                     /gene="dnaJ"
                     /locus_tag="KB913_001512"
     CDS             12482..13648
                     /gene="dnaJ"
                     /locus_tag="KB913_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBB6819880.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(13730..14395)
                     /locus_tag="KB913_001513"
     CDS             complement(13730..14395)
                     /locus_tag="KB913_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6819881.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            14371..14544
                     /locus_tag="KB913_001514"
     CDS             14371..14544
                     /locus_tag="KB913_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819882.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(14589..15326)
                     /locus_tag="KB913_001515"
     CDS             complement(14589..15326)
                     /locus_tag="KB913_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6819883.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(15328..16830)
                     /locus_tag="KB913_001516"
     CDS             complement(15328..16830)
                     /locus_tag="KB913_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBB6819884.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            17089..19083
                     /gene="uvrB"
                     /locus_tag="KB913_001517"
     CDS             17089..19083
                     /gene="uvrB"
                     /locus_tag="KB913_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBB6819885.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            19093..21909
                     /gene="uvrA"
                     /locus_tag="KB913_001518"
     CDS             19093..21909
                     /gene="uvrA"
                     /locus_tag="KB913_001518"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBB6819886.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            22172..23437
                     /locus_tag="KB913_001519"
     CDS             22172..23437
                     /locus_tag="KB913_001519"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBB6819887.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            23441..24172
                     /locus_tag="KB913_001520"
     CDS             23441..24172
                     /locus_tag="KB913_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBB6819888.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            24307..25191
                     /gene="rapZ"
                     /locus_tag="KB913_001521"
     CDS             24307..25191
                     /gene="rapZ"
                     /locus_tag="KB913_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBB6819889.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            25188..26186
                     /locus_tag="KB913_001522"
     CDS             25188..26186
                     /locus_tag="KB913_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBB6819890.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            26220..27155
                     /gene="whiA"
                     /locus_tag="KB913_001523"
     CDS             26220..27155
                     /gene="whiA"
                     /locus_tag="KB913_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBB6819891.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            27698..28348
                     /locus_tag="KB913_001524"
     CDS             27698..28348
                     /locus_tag="KB913_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819892.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            28535..>29097
                     /locus_tag="KB913_001525"
     CDS             28535..>29097
                     /locus_tag="KB913_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HBB6819893.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT         9566 a         4897 c         6176 g         8458 t
ORIGIN      
        1 aaaggggctg tgacaaaagt cttgtcacag cctttttttc caaataaatg gtttttcaga
       61 agtagcttct tcggaaataa gccgaaattt cttgaagctg accacttctg tcacaacctc
      121 tttctttata gaaataaaag gacactagca attcatgaaa acgattgcta gagcgtatca
      181 tttgctttag actatatatc ttggtgtaca ctcactttaa ggcggaaata aaagttatcc
      241 gtaataacag gtttaggtat gaaaaaggag tgggtactat gtacaaggaa ttagaaaaca
      301 aagtcgcagt agtaactggt ggctcaaagg ggattggaac agcgattgct caacgattcg
      361 ggaaagaaaa aatgaatgta gttgtcaact ataactcgga taaagaagga gcagaaaaag
      421 cagtcaaagc aatcgaagag gcaggcggaa aagcagtctc tgtacaagca gatgtcagtt
      481 ctgaagaagg aatacagcgt ttacttgata cggctttaga aaattttggg acactggacg
      541 tttgggttaa taatgctggg atggaaaatc agcatccaac ccatgaactt agccttgaag
      601 attgggaaag agtgttaaaa gtcaatttga ctggcgtttt tatcggaacg aaagcggctt
      661 taaattactt tacagagaat aataaaaaag gaaatatcat caatatgtct tctgttcatg
      721 aacagatccc atggccaacg tttgctcatt acgctgcttc aaaaggcggg gtaaaattat
      781 ttaccgaaac ggtagcaatg gagtatgcac cgaagggaat cagaatcaat agtataggcc
      841 ctggtgctat ccgtacacct attaatgcgg caaaatttga tgatcctgaa caaaaagaac
      901 tcttggaaag tatgatccca ctaggacgcg taggtgaacc aaaagaaata gcggcgacag
      961 ctgcatggtt ggcttcagac gaatccagtt atgttacagg tattacacta tttgcagatg
     1021 gtgggatgac tttatatcct tctttccaag gtggaaaagg ataagggtga ataaaaatgg
     1081 gtttattgat tgcattgatc ccggcagttg gctgggggat ccagccactg attttgaaaa
     1141 agattggtgg cagaccaaca aatgagatat taggaactgg tattggagcg gtgcttgtcg
     1201 gcttactcgt tcaattattc gcttctccag ctggtatttc agtgactaca tttttgatta
     1261 gtttactttc tggtgcattt tgggttattg gacaaacagg acagtataca tctttcaact
     1321 tgattggtgt ttctaaaacg atgccaattt cgactgcatt acagttagtc ggaacctcgt
     1381 tgattggtgt cttcgctttt ggagaatggt ctggaagtat ggggaaaatc attggagcag
     1441 cagcaatcat tcttcttgta tttggttctg ctttaacggc aatcagtgat gatcctggaa
     1501 aaaaaggcgg tatcacaaaa ggaattagtc tattagcatc aacaagtatt ggttattggg
     1561 tatacagtgc attgcctaaa ctagttgatg caagcggact ttccattttc tttccgcaaa
     1621 tgatcggtgt ctttttaggg gcagtgattt atgtgatttt ccgtaaacca accgcatttt
     1681 ctgaagacaa gagttggaaa gcaacgatcg ttggagccat ctttagtgtg tcagcattgg
     1741 cttatatttt ttcagcaaat gaaaatgggg ttgctactgc atatatcatt acacagctaa
     1801 acgtagttat ctctacatta ggcggtatgt acatcctgca tgaaaataag acaccaaaag
     1861 aaaaaaaatt aacgattatc ggattattgc tgatcgtagt aggaagcatg gtcacggtct
     1921 ttatttgagg ataaagatgg taaaatttca tttattaaaa aaatatttgt ttgaaccaaa
     1981 cagtaagtac ttataaaaaa atagcgctag aatttccaac atctctggaa tttctagcgc
     2041 tttttaattg tttaagatac aagggaaata tctgtctgga tcaataattt ttcattgatc
     2101 cattgactaa agtttacgac ataattgaag ttaccaccga ttagtatctc cgcatgattg
     2161 tctttataaa gatcgtattg taaaagacgg tcttttttat ttgcgtaaac atcgttatgg
     2221 tactggacta attgttctcg gaattgattg attgctgtaa aatcacgata ttgaaggttg
     2281 aaacgcatcg tgattggtgc atttagcatg aatcgctgca tttcttttgc tgcttcctct
     2341 gcttgatctc cgtataggaa ctcaaaaaga ttacgttcag aaaatttcca ttgcccgcca
     2401 acctttgttc cttttagttt tccttcatga agataatttc tgatagaacg tgtagtaaca
     2461 cctaattgtt cggctaattc atttactgag taaaaatctt tcaatgttca ccctcctatg
     2521 tgaatggttc tactgactta gttgatattt gcttaatcac gaaatgtaga aagaacgatt
     2581 ttaattaagg tcattgtaaa aatcaagtca gaaaattcta acttttattt ctctaaagaa
     2641 attcgttctc tcctaaagtg atattatatt taaatatacc tgaaaataat gggcagtatt
     2701 atgaaagatc actgatattt tctcgtattt tttccttatt caaaagtttt gcaggaaaat
     2761 tgctgaaaaa ataattttac taagtagaaa attcaaagcc attcaatcag tgattttttt
     2821 cagcacaaga aagactcctt ataaaaatag cagatacttt gtcaattaag tgtttaacca
     2881 gggatgataa aaaggatagg attgaacaaa acctgtataa ggtgatgaat agtttcctcg
     2941 ccagtaaaag gtttattcgt ataaagcttt atcgccaaaa tttatcatga ccttttttat
     3001 cttcaatatt aaatgaaatc aattgttcaa tcaattccca gttgattaca cttttccaag
     3061 gaactttgat gacgttatcc gtatatacgt agcctgcttc ttggatattt ttttcaaggg
     3121 cacgaatcgc tgctttttcc ggtgcgatag aaaaatgatt tttagcaaaa ctaaatgcaa
     3181 taataaaggt accatggtca gtaaacatag gttggttcca ttttacagtt gtgtctagct
     3241 ggggatacgt ttctgttatc ttagcaaaaa ggtctttgat cttttgttga tgttcttttt
     3301 ctttgatttg attgatgatc ggctgaaatt tttccattct aaaacgcctc cattaagtgg
     3361 tttgatttat tttaccagaa aaacaatagt tatgtataaa aaacgaacaa aacacaagta
     3421 atgttgtaac cgctatattt atatgataag atgtctcaaa taataaaata gaaaagagac
     3481 ataaaaatga ttgacttggc aaagaaattc ttacacgaaa atatatattt tgagttgtat
     3541 catcatcgag ccatttatac aaatgaagat gctttggtaa taaagaaaga acaaggattt
     3601 acaggtacag agaccaaaag cttattctta aaagataaaa aagataataa ctacgtatat
     3661 ctgactttta ctacgaaaca aacggatttc aaagcattag ggaagatcgt cggtaaaagg
     3721 ctttctattg tttcatcaga acgcatggaa gaacaaacgg gacaaaagca gggcgctgtt
     3781 tctccgtttg gttatgaaaa acagattccg attattattg atgaagagct cttatcaaat
     3841 gaaaaacttg tttttgcacc aggtagacca gatcaaacga tggtcatcca aacggttgac
     3901 ttaaacaaaa tcatccagct acttgagatg ccgatatttt tgatgccggc aaacgaaaaa
     3961 aacaattaac caagtaaaat agtgcatact tggaggtgaa gcaacatgat aagttatcca
     4021 ttattagaaa gaaatgcaac gattggggtt actgcaccat cctcaggcgt atcagaggaa
     4081 caccattcgt tactcgaatc agctttaaag agaatggaag aaaaatcttt ccaagtagtt
     4141 actggaaaga cgctttggac gcaagataag gaaaaatcag gtccagcaag aaaacgagca
     4201 gatgaattca atcaaatgat gcaagatgaa aatatccaaa tgatctttcc gacttgggga
     4261 ggagaattat tgattgagat tctcgatttt gtcgattttg atgctctaca accaaaatgg
     4321 atagtaggtt attcagatat tagtacgttg ctacttgctg tcacattaaa aacagggata
     4381 gccactgcac atggaactaa ccttattgat ttaagaggag agtacttgga tgaaacgaca
     4441 gcaatgtggg aaagtgtact gaaaacaaga gaaggagaat cgattctaca gcaatcttct
     4501 gaaaagtatc aaaaagtgtg gccccatgag cattcatcat cttctgtttt ccatctcact
     4561 gaaccaacaa attggcaatc agtcagcgga gatgcagtaa ggatgaaggg acgattatta
     4621 ggtggttgta ttgatacgat caggcattta atcggtactc cttatggaga tgtccaatct
     4681 tttaaaagaa agtataatga tggaaagccg atcttgtggt ttctagaaaa ctgtgagcta
     4741 tcgtcagttg atttaagaag atcacttgtt cagatgaaac tggcaggctg gtttgatggc
     4801 agctcgggga tcatgttcgg tagaagtgcg gcagaggatt tgttagatta taaaatgaag
     4861 gatgtatacg aagatctgtc aaaggaatta aaactaccga tcttgtatga tattgattgt
     4921 ggtcatgtac cgccacaact gacattgatt aatggtgcct atgcagaagt agcggtagaa
     4981 gatagaaaag cgactgtttt gcaaacgttt atttaaaaaa ttttttcctg ccttggagtc
     5041 tatcaaagac caataaatct aaatagaaaa gaaagtgaaa gaagctgaca aaatgctgtc
     5101 agcttctttt tgtataacat attagaaagt ctaattatct ataactgtca catcgattaa
     5161 ctgtttcacg tcattgggat ttcctgtagg aatagctact acagatgcat tatcaatgat
     5221 ttcttgagtt gtttctctaa tgaacgctgg ataagatgtt tgatctgcag gcatttgcca
     5281 atgtgaagga actggataac tagtgattgt cccgtcatgg ttacttgaat acactaaaac
     5341 tccctggtaa ctgtatttcc cagtgagcat aaccacatct ttcggataga ctgcactccc
     5401 tgcatcataa ggggcgatag gtgttcctgc aggataatga ataacatgta attcgaaatc
     5461 acccgatgta tctctaaaag tattacctct aatagctagc caaacacgtg cgtactcaat
     5521 ttgtagatca gaatatcctg ctaacggatc tattgactga gaagactgtg aggaggttgt
     5581 gtctattgtt gaagaagaaa tatttgtctc aactgtacta ctagatgtag aagaagtatt
     5641 gggctctgag actttactgc ttgttgaaga tgtattcgtt tcagtagaag ctgatttctg
     5701 agtacttgat ttttcagctg aactggtttg tctgattgaa cttttgtctg tggtcgcaga
     5761 tggatcacta ttttctttac taggagacgt acatcctaca aggaataaag agaccaacaa
     5821 taaaataaaa cctaactttt tcatataaaa tacctcatta tttttttaat accagtatag
     5881 cataatcctg aatttttgaa tccgtaaaac cttgtctatg aatataaata gagtgtatct
     5941 tctttgataa atgtcagaaa aagtgtgaca aataatcatc agtaaaatta cttgtcacac
     6001 tattgataag gagtatttaa ttgaagagaa tgattaggag aaaggatctc cgtacttttt
     6061 atagtaatca tagaatccaa gtttgtatag acgaatcgtt ttttctctta tttcttctgt
     6121 ttcaaaatgg actgcttgaa gaatcaagtc tgtgaattct ataggagctg ttccattcgc
     6181 agtaatcaaa ttacgatctt tcacagcttg ttgttctata aaatcttctt tattctgata
     6241 attttccgat tctaaccaag gaaattgcgc atttccggtg tgtttgtaac cttgcaataa
     6301 tccgctctga gctaaataat caactgcccc acaaatagca gctactggta cgtctgtttt
     6361 taacaattta tcgattattt gatataaatg atgatttttt atgtcccatg aattgccacc
     6421 gatcataata aaaaggtcaa ctttttcagg tatttgttcg attaagtaat cgatttttgt
     6481 ttttaatcct ccaatggaag tgacctctga ttggatagaa gcagttttgt tttgccattt
     6541 ctcattttgg tttagtgtgc tagtaatata agcaccttcc caatcggcat attcctctaa
     6601 tagaaacgta atcgcagttt tcattttcaa gctctccttt actatctata acaaggacaa
     6661 cagttttaac ctacagacat tcattaaaat tgggtagcga cagcgaaaac aacaattctt
     6721 aagttttaga cagagtatac agatagtcaa cttaattaaa tacgaactaa ataaaaatga
     6781 caggtaatca tttttgttta ccagcattat aacattttgc atacatggat gacaaaagaa
     6841 ccaattccca cttgcttgag tacaatatta aaagaaactg gaaggcaaaa agtaattata
     6901 gaaacgaaaa ataaatcata tcgggcactc agacatgaaa acaaccctag agatatataa
     6961 ctaggtaacc agtttaatga aagaaaaaat catccaagaa gtcgattctt ggatttttta
     7021 gtggatttgt tcgccaaata cgtttagtat gcgtatatga gaggttgtaa gcaaagcgtt
     7081 gtggtctgag cacttaagga ggaatctgtg aaaatagctt ttcatatttt tgcagatttt
     7141 gacttaatgc cgaaggtcag ctttgcgatt accgtttatc gagaggctgt aaaagcaccg
     7201 tgtagctccg atgacaataa gcaagcattt ttagagctag gtttccttga ttctaaatat
     7261 gcggcttatt tcaatgagtt ggtgcttgaa cgcgatttta agaaggtcga aaacaggcac
     7321 gacttttcga cgtaaggaga aagaatttca atgatagaaa caataaatcc cgcagaaaac
     7381 aaggtttctg cgtacattca tatcccattt tgcgagcata tctgctatta ctgtgatttt
     7441 aataaagttt ttttagaagg gcagccagta gatgagtatg tggaaatgct gctgaatgaa
     7501 atgaaaataa tgctagaaag tcatccgaca gcgaatttag aaacacttta cgtagggggc
     7561 gggacaccaa cttctttatc tgctaaacaa cttgatcgac tgttatcagg tgctagagag
     7621 atcctgcctt ttcaaaatgg taatgagttt actgtagaag cgaatccagg tgatttgacc
     7681 cgtgaaaaac ttcaagtaat gaaaaactat ggcgtcaatc gtttatccat gggagtgcag
     7741 acatttgata atcgcttatt gaaaaaaatt ggacgtaaac acaccgcaga agatgtgtat
     7801 caaactatgc aatttttaga agcagaaaat tttaccaatg taagcatcga tttgatttat
     7861 gcattaccgg gacaaacact agaaggatat ctggatactt tggaaaaagc tttggctttg
     7921 gatctgcctc actattcttt gtactcattg atcctcgaaa acaaaacaat gttcatgaac
     7981 tgggtacgac aaggaagact cgaactgcct gatcaggaaa cggaaaccag aatgtttgaa
     8041 gagacgattg aagcaatgga aaagcatgga cgtcaccaat atgaaataag taactttggg
     8101 ctctccggac atgaatctca acataacctc atgtactgga acaatgccca ctattttggg
     8161 tttggagctg gtgctagcgg ttatcttgga gatattcgtt accgcaacaa aggaccaatc
     8221 caacactatt tacgcccatt acgagcaaat gaacgcccgg tattggaaga agaaaaattg
     8281 acacgaaaaa atcaaataga agaagaaatg ttcttaggac taagaaaaaa aacagggatt
     8341 actaaaaaac atttctatga tcgctatcaa aaaacaattg aatcggtgta cggtgatgtg
     8401 ctaagggaat tagagcaaga agggttactt gttaatgaag aagaccgtgt ttatttgaca
     8461 ccaagaggga cctttttggg gaacaatgtg tttgagcgct ttttgtttga aaaatagttt
     8521 aaagaatatt tgttttttat ctgaatttaa ataaaaaaag ttcaaaaata caataaagga
     8581 ctattgaaac gttgatataa ctggatttac atcaattatt tagaattagc actcttgtgt
     8641 ttagagtgct aaaaaatgga gtctttctct tgacaggaga agggcttctt gctatattta
     8701 taagtggatt agcacttaga atatatgagt gctaatgaga ggtgaggaag atgttaacaa
     8761 agcgacaaaa cgacatttta cgtctgatca tccaacacta tacgagtagt ggcgtgcccg
     8821 ttggttccaa aacattgatg tctgagggag tcaaggccag ctcagcaacg attcgcaatg
     8881 atatgaaagc attagaagat gaaggattgc tgttgaagac tcactcttct tctgggcgga
     8941 ttccatctgc tttaggctat cgttattacg tggatcattt gttaaaacct gctcgcgtag
     9001 cagaagatga tttgctgctg attcgtcagt ctctaggcag agaatttcat gaaatcaatg
     9061 agattattaa gcaatctgct gagatattat ctgagctgac aagctatacg actttttcat
     9121 tgggacctga aataaaagac cgccgactga ctggctttcg tatcgtaccc ttgaataatc
     9181 gacagattat tgctatcgtc gtaacagata tggggaatgt agaaagccaa gtgttcactc
     9241 ttcccgaata tatgggaagt caggaactag aaaaaatggt acagattgta aacgaccgtc
     9301 tagtcggaga tcctctgatg acggtgtacc ataaacttcg tacggagatt ccgatgattc
     9361 ttcataaata tttccaaacg acagaaggga tgtctcagtt atttgacacc gttcttggtc
     9421 atgtttttga agataaggtt tatgtcagtg gacaaatgaa tctcttggat tatgagcccc
     9481 gtcaagatct tgatcagttc aaatcgatgt tttcttttat gaaagactca gacggactta
     9541 cacaaatgat cactccgatg gatagcaata ttcatatcaa gattggtgct gaattaggca
     9601 atgatttatt gcagaatatg agtatgattc aagcaagtta cgagatagat ggtcatggaa
     9661 gaggtacaat agccttgtta gggcctacta gtatgcctta ttctcggatg ttcggtctag
     9721 tcgatgttta tcgaagagaa ctagcagcta aacttgctga ttactaccgt tcgcttgact
     9781 tgtcaaactc gtaatgtgaa taacgaagct atttgcagct gatcgttctc tctttcttag
     9841 taagagcaat caaacagctg actgaataat gaaaggaaga ctgtatcgtg aaagaaaatc
     9901 aagaagaact agataaagaa atgacagatg ctcagccaga accggaaatc gatgtcgaag
     9961 ctgcagaaga ttcgggtatt tcagaagctg aagcggaaga attcgaaaca gcgaaattaa
    10021 aagctgagtt agaagaaatg gaagataaat acttgcgggc tcgtgctgaa atcgcaaata
    10081 tggcaaatcg aggaaaaaat gagcgtgagc aattacaaaa ataccgttca caagatttag
    10141 ccaaaaaatt acttccatca attgacaacc tggaacgtgc attagccaca gaagtgtcag
    10201 atgatcaagg ggcaggtttg aaaaaaggcg tggaaatggt cttggaaagt ttgcgtaacg
    10261 cactggaaga agaaggaatt gaaaaaatcc ctgctaaagg agaagccttt gatcctaatc
    10321 ttcatcaagc agtacaaact gttccagcga ctgaagatac accagccgat acgattgtag
    10381 aagtactaca agaaggctac aaattacatg atcgcgtgtt aagaccaacc atggtcattg
    10441 ttgcacaata attgtgcgga tataaaactt acactttcaa ttaaagaagg agacgttaat
    10501 tatgagtaaa attatcggta ttgacttagg tacgactaac tctgcagtag cagtattgga
    10561 aggaaacgaa gcaaaaatca tcgctaaccc agaaggaaac cgtacaacac cttctgttgt
    10621 atcattcaaa aatggagaaa tccaagtagg ggaagttgca aaacgtcaag ctgtgacaaa
    10681 cccaaatacg atttcatcaa tcaaacgcca tatcggtgaa gcaggttaca aagtagatgt
    10741 agaaggtaaa tcatatacac cacaagaaat ctcagcaatg atccttcaat atatcaaagg
    10801 attcgcagaa gactatttag gtgaaaaagt cgaaaaagca gttatcactg tgccagctta
    10861 ctttaatgat gcacaacgtc aagcaacaaa agatgctggt aagatcgctg gtctagaagt
    10921 agaacgtatc gtcaatgaac caactgcagc tgctcttgcc tatggtttag ataaaacaga
    10981 tcgcgacgaa aaaatcttag tattcgacct tggtggcggt acttttgacg tatctatcct
    11041 tgaactagga gacggtgtct ttgatgtatt gtcaacagct ggcgacaacc atctaggtgg
    11101 ggacgacttt gataacaaaa tcatcgacta catggtagca gaattcaaaa aagaaaacag
    11161 cattgacttg tctcaagaca aaatggcttt acaacgcttg aaagacgctg ctgaaaaagc
    11221 gaaaaaagat ttatctggcg tatcaagcac acaaatcagc ttgccattta tcacagcagg
    11281 agaatctgga ccattgcatt tggaaatgac attgacacgt gcaaaatttg atgaattaac
    11341 agctgactta gtagaacgta caaaagtacc agtacgtcaa gcgctaaaag atgcaggttt
    11401 atcacaatca gaaatcgacg aagttatttt agtcggtgga tctactcgta tccctgcagt
    11461 tgtagaagca gtacgtaaag aaacaggaaa agaaccaaac aaatcagtta accctgatga
    11521 agtagttgct atgggtgctg ctatccaagg tggcgtgatc actggtgatg tgaaagatgt
    11581 tgttttactt gacgttacac cattgtcatt aggtatcgaa acaatgggtg gagtgttcac
    11641 taaattgatt gaccgcaata caacgattcc aacaagtaaa tcacaagtat tctcaactgc
    11701 ggcagataat caaccagcag tagacatcca tgtattacaa ggtgaacgcc caatggctgc
    11761 tgacaacaaa actctaggaa gattccaatt gacagatatt ccagcagctc ctcgtggtat
    11821 tccacaaatc gaagtaacat tcgatattga taaaaacggg attgtaaatg tatctgcgaa
    11881 agatctaggt acacaaaaag aacaaaaaat cacgatcaaa tcttcttcag gtctaacaga
    11941 cgaagaaatc gaacgtatgg taaaagatgc agaagcaaat gcagaagcag ataaagctcg
    12001 taaagaggaa gttgacctac gtaatgatgt agatgcattg ctattctctg tggacaaaac
    12061 attgaaagaa ttagaaggca aagtggacga agaagaagtg aaaaaagcag aaacagctcg
    12121 cgatgaattg aaagccgctg ttgaagcaaa caacatcgaa gaaatgaaaa ctaaacgcga
    12181 tgcattgaac gaaatcgttc aaaacttgac tgttaaacta tacgaacaag cggcacaaca
    12241 acaagctcaa gaaaacccag aagcagctca aggcggagca gatgatgtcg ttgatgctga
    12301 ttttgaagaa gtcgatggcg acgataaata atcagttcac tgaatttcga gagaaggcca
    12361 aagttgctac tttggctttt tcttttgaaa aatagtttga agtatcggtt tttgtttcaa
    12421 acaaaatatg atatgataac aagcgacgtg aaaatgatga gaaccaatag gaggaaagcc
    12481 tatggcaaca aaacgtgatt attatgaagt cttagggctc tcaaaaggag catcagaaga
    12541 tgaaataaag aaagcttatc gtaagctttc gaaaaaatac catcctgaca tcaataaaga
    12601 acctgatgcg gaagaaaaat tcaaagaagt atcagaagca tatgagattt taagtgaccc
    12661 gcaaaaacgc gctgcatatg accaatacgg gcatgcaggc acagatccaa attacggtgc
    12721 tggtggagct ggtggcggat ttggtggatt cggcggcttc tctggtggcg gcttcggtgg
    12781 ttttgaagat atcttcgact ctttctttgg aggaggcggt cggtcagtcg atccaaatgc
    12841 gcctcgtcaa ggtgctgatt tgcaatatac ggtcgacttg tcttttgaag aagcgatttt
    12901 tggtgtagaa aaagaaatca agtataatcg ggaagaaatc tgtcatactt gtggtgggaa
    12961 cggtgcaaaa ccaggcacac aaccaactac ttgtcataaa tgtcatggtg caggtacgat
    13021 taatgtagaa cgccaaacac cacttggacg agtgatgagc cgtcaaactt gtgatgtttg
    13081 tcatgggaca gggaaagaaa tcaaagaacc ttgtccaacc tgtcatggct caggacatga
    13141 gaagaaagca cattcagtta aagtgaatgt accagctggt gtagaagaag gacaacaaat
    13201 gcgtttagct ggtcaaggag aagctggaga aaacggcgga ccatttggtg atttgtatgt
    13261 ggtcttccgt gtagaagaaa gtgatatctt tgatcgtgaa ggttctgaaa tttactatga
    13321 attgccttta agttttgtac aagcagcttt gggggatgaa gtccaagtac caactgtcca
    13381 tggagatgtg aaattgaaga tccctgctgg aacacagaca ggtacgaact tccgtttacg
    13441 tggaaaaggc gctccgaagt tacgtggtgg tgcaacaggc gaccaacatg tcaaagtaaa
    13501 actgatcaca ccgaaaaatc taaatgaaca acaaagagaa gcattacgtg cattcgctga
    13561 agctggcggc atcaaagttg aagaacagca agaagacggt ttcttcgata agtttaaaga
    13621 tgcttttggc gggaaaaagc ggaagtagtt tttctagtaa aaacgctaag tcattaataa
    13681 ttaaaaacca gacgaacaat catatgttcg cctggttttt ttgtagttgt catgtttgta
    13741 ccaacaaaaa agccagcttt agaatatgat aatcgtcata gtttctaggg gtataaccag
    13801 tgagagaatg gaacttgttc aatcgatatt gcaaggtgtt tttatgaata aataattctt
    13861 ctgagcaatt tttgatgctt ccgttatttt tactgaagca tgccaaagtc ttcttgaaca
    13921 aatgtacttc ttcttctgtc aggcttttca aaatacgttt tacatataat gttcgttgat
    13981 ctgacgggat tgctggtaaa acgatcccga ggtctaaatc ttcaaaaaag cggatctcgt
    14041 tcacagattg atggaaagct atccattcgc aaacttgttt ggcatgaagg aaagattgcg
    14101 gtgtctcttg ctctgtataa caaagcgacc caattccaaa gtttagctgt aactgataca
    14161 ttttattaaa ctttgtctgg attttatcaa gcaatgatag caatgaggct ctggaaatcc
    14221 gattgactag gataatgatt tgttgtctat gtacagtgag caaagcctgt ccgtaataag
    14281 agaagaccct ttcgagcaac tccaataaag gattgatccg ttcttgacac aattgctgat
    14341 tgtcagaaag ttgtcccaca actacataat atggagaaga aaaatcaagc tcaattaagt
    14401 gagggtggta tcgactatgt acttgatatc atcaatgaac cgatggtact ttcttatgcg
    14461 atggaacagg tagagcgatt gcttgtttgt gcaggaaaac aagcgatgcg gctgatacga
    14521 ttaggtgaga aaataagaag ataaaaatac acggtccctt catggcgacc gtgcattttt
    14581 ggtttttatt aaatatttaa tactttattc aagaaatctt ttgtccgttc attttgcgga
    14641 ttttcaaaga tttgttgagg cgttccatct tctaaaaagt ttccgtcgtc aatgaacatg
    14701 acgcgattgg ccacttcttt agcgaacccc atttcgtgcg taacgataac catcgtcata
    14761 ccttgttctg ctaacttttt catgacgttc aagacatcac cgaccatttc aggatcgagt
    14821 gcagaagtag gctcatcaaa aagcatgatg tcagggttca tcgctagagc acgagcaata
    14881 gccacacgct gtttttgtcc accagaaagc atttcaggat acatatcttt tttatcttct
    14941 agaccaactg tctgcagtaa tttgattgct tttttctctg cttcttctct agattctttc
    15001 ttcaggtcca tcggtgctaa aatgatgttt tccaaaatag aaagatgagg gaataggtta
    15061 aagtgttgga ataccattcc gatatgttgt ctcaccaagt tgatatctgt gcttttatcc
    15121 atcaagtggg cgccgtcaat aataatttca ccgtcagaag gttcttctaa acgattcaag
    15181 caacgcaaga atgtactttt tcctgaacct gaagggccaa tgatacagac gacatctcct
    15241 tcgttgatgg atacattgat gtcgtttaat actgtgttat cgccgtattt tttgactaaa
    15301 tgctcaacta agattttttc tgccatctta cttcaccttc ttttctaaaa cttttgctaa
    15361 ttttgtcaat gctgtgatca aaatcaagta catgatcgca atgatcaagt aaacatacgt
    15421 actttgtgtt gtacgtgcaa caatgatctt accagtttgc agcaattcga ctacaccgat
    15481 tgcggaaatg atcgttgtgt cttttaatga gataacgaac tgattgacga atgatgggat
    15541 catgatgcgt atcgcttgcg gcaaaatgat tttttgcatt gtccgattat aagaaagacc
    15601 taaacttctg gaagcttcca tttgtccgac aggaacggcg ttgatcccgc ctcgaacaat
    15661 ctctgcgata taagcacttg cgttaagagt caaggtgata acaccagcaa ggaagtcagg
    15721 aatcgtaaat ccaacgatac caggcaaccc aaagaaaata aagaacgcaa gaaccatcat
    15781 tggaattcct cggatgatat cgacataaat actagcaatt gtgcgaagag cgcgtattgg
    15841 tgctacactg aataatccaa aaatcacacc gattactata gccaaagcaa aggagatcaa
    15901 agttaggaga attgttctcc aaagtccttt caacaatgct tgatagttgt tttggataag
    15961 tccaagaaat gttgattcat cagcagtgga agactcactg gaagtttctg aaccatccgc
    16021 tacatattct ttaataatct tatcgtattc gcctgttctt tttaattctt tcaatccttc
    16081 attgaacata ttaagaagct caggattttg tcctttttta acggcaaatg catattttcc
    16141 gccagattct tttttgatcg gtgtttccaa ttcttgtcct tgtttgatcg cataaccgat
    16201 taccggataa tcatccatca ttgcatcgat tgcgccaact tttaacccgt cgtacaattg
    16261 atcagcagca tcaaaatatt tgatagaata gccatattca gattcatggt cgcttaaaaa
    16321 ttcagcactt tcggtaccaa cttttgctcc gactgttttt cctttcaaat cttcataaga
    16381 cttgatcgaa gtatctcctt ttttgacagc taattggatc ccgctatcaa agtaagaatc
    16441 agaaaaatca tagcttttct ttcgttcatc tgttacagtc attccggcaa tcattccgtc
    16501 tgcttgtcct gattccaaag cttgcaaagc agcagagaaa ccacggtagt ccattcggat
    16561 gttaaatcct tgcagtttgg cgatgttttc catcaatttt acatcgatgc cttcgtactc
    16621 gccctttgcg ttttgaaatt caaatggagc aaaagcagag tcactggcaa ttacgtatac
    16681 gtcttttttg ggctctattt tttgcattgt ctcgcttgtg cttgactctg ccgttgtagt
    16741 gttgtcagct tgtgcaacat gaccaaacgc aagtgtcaca agtcctgtca ttaagaaaac
    16801 aaatgagtga aataaatgct ttcttttcat aatcaacctc ctaaatttcc aatattttat
    16861 tattataggc gaaaagtgct gaatcagaca agactgtaag ctcgaaaaaa tgaaaaaaat
    16921 gcgagtttct aacattttat gttataaaac ataacatgta taataagata aaaaagtggc
    16981 gaaagtatgt tcggtgtggt ataatttttt agtaaggaat gcctttgctt tccttttctt
    17041 tttattggtc gtaaaatgaa aaggaatgaa tgaaaaggag gacgaagaat gattgagaga
    17101 gatacctccc gacactttga gcttgtctcg aaataccaac cggctggtga tcagcctgaa
    17161 gcgattaacc aattagtgga tggcgtagtc ggcgggaaaa aagcacaaat cttattaggt
    17221 gcgactggaa cagggaaaac atatacgatt tccaatctta ttgagaaagt gaataaacca
    17281 acactgatta ttgcccataa caaaacattg gctggtcagc tgtacgggga attcaaggaa
    17341 tttttcccta acaatgctgt tgaatatttt gtttcttatt atgattatta tcagcctgaa
    17401 gcttatgtgc cttcaagcga tacgtatatc gaaaaagatt caagtgtaaa tgatgagatc
    17461 gacaaattac gacattcggc tactagttca ttattagaaa gaaatgatgt gatcgtcatt
    17521 gcatccgttt catgtatttt tggattaggc tcgccttttg agtaccaaaa acaagtagtt
    17581 tcgattcgac agggagcaga actagatcgc aatcagttga ttcgtgactt agtcagtatc
    17641 caattcgaaa gaaatgatat agattttcag cgcggtcgtt ttcgagtgcg cggtgatgtc
    17701 gtggagattt ttccggcttc aagagatgaa cgtgccttac gtgtggagtt ttttggagat
    17761 gaggtcgaac gtatccgaga agtcaatgca ctgacaggtg aagttttagg agaaacggaa
    17821 cacgtagcaa tcttcccggc gactcacttt gtgacgaatg atgaacatat ggagcatgcc
    17881 gtagcgaata tcaaagcgga attagaacag cgtttaactg tcttgcgaaa tgaaaacaaa
    17941 cttctggaag ctcaacgttt agaacagcga accaattacg atattgaaat gatgttagaa
    18001 atgggctaca cgtcgggaat tgaaaattat tctcggcata tggacggacg taaagaaggt
    18061 gaaccgcctt atacgctatt ggatttcttt cctgaagatt ttttgatcgt ggcggacgaa
    18121 tcgcacgtaa ccatgcctca aatcagagga atgtataatg gtgaccgagc gagaaaacag
    18181 atgctagtag attacggttt ccgtttgcca tctgctttag acaatcggcc acttcggtta
    18241 gaagagtttg aaaaacatgt caatcagatc atttatgtct ctgcgacgcc aggaccatat
    18301 gaacatgaac aaacagatac cgttatccaa caaatcatcc gtccgacagg gctgcttgac
    18361 ccagtgatcg aagttcgtcc aatcatggga caaatcgatg atctagtagg cgaaataaat
    18421 gaacgagtcg aaaaagacca gcgggtgttt gtaacgacat tgacgaaaaa aatggcagaa
    18481 gacctcacag attatttcaa agaattaggg atcaaagtca aatatttgca tagtgatatc
    18541 aaaacgctgg aacgaacaga aatcattcga gatcttcgat taggtgaatt tgatgtgtta
    18601 gttggaatca atttgcttcg tgaaggatta gacgtacctg aagtttccct tgttgctatc
    18661 ttggatgcgg ataaagaagg ctttttacgt agtgaacgtt ccttagtcca aacgattgga
    18721 cgagctgctc ggaatgaaga aggtaaagta atcatgtacg cagacaaagt aacagattct
    18781 atgcgtctag cgatggatga aacgtcaaga cgtcgtacga ttcagcagaa gtacaatgaa
    18841 gaacatggga tcgttccaaa aacgatcatt aaagaaatcc gagatttgat ttctattacg
    18901 aaagaatcgg aagatgatac aaaagaagcg gtacaagtct cgtacgaaga aatgacgaag
    18961 gaagaaaaag acacgttatt gatgaaatta gaaaaagaaa tgaaagatgc ggcaaaagct
    19021 ttggattttg aaacagccgc gaatgtgcga gatatgattt tagaattaaa agcttcaaag
    19081 taggaggaca acatggctaa cgataaaatt acgattcatg gtgcacgtgc ccataacttg
    19141 aaaaatatag atgtaacgat tccacgagat aaattcgtgg tcgttacagg tttgtccggt
    19201 tctggaaaaa gttccctagc atttgatacg ctgtacgctg aagggcagcg gagatacgta
    19261 gagagccttt ctgcttatgc tcgtcagttt ttaggacaaa tggataagcc ggacgtagat
    19321 agcatcgacg gattgagtcc ggcgatttct attgatcaga aaacaacaag taaaaatcct
    19381 cggtcgacag taggtactgt gacggaaatc aatgactatt tacgcttgtt gtttgcacgt
    19441 gtaggacatc cgatttgtcc caacgatcat atcgagatta ccagtcaatc agtagatcaa
    19501 atggcagatc aagtaatggc tttgcctgag cgcacaaaga tccaagtgtt ggcaccgatc
    19561 gtggtaaaga aaaaaggaca acataaaaaa atattcgaac gaatccaaaa agagggatac
    19621 gtccgcgttc gagtcgatgg tgagatctat gatttaagtg aagtgcctga gctggagaaa
    19681 aacaaaaaac atgatatcgc gatcgtcatc gaccggatca ttgtgaaaga agggattcgt
    19741 tctcgcctat ttgattcttt agaggcggcc ctgcgattag cagacggcta tgctctggtt
    19801 gacgtgatcg gtgaagaaga aatgttgttt agcgaacact atgcctgtcc ttattgcgga
    19861 tttactgttg gcgaactaga accaagactg ttctcattca atgcgccttt tggagcttgt
    19921 ccagactgtg atggtttagg tgtcaaatta gaagtcgatc aagatttagt gattccagat
    19981 agaacgaaga cacttagtca aggtgctatc gttccatgga atccaatcag ctctcagtat
    20041 tatcctcaaa tgttagcgca ggcttgtgaa agtttcggta tcgatttaga tacaccattc
    20101 gaagaattac cggaagagca tcaggagatc atcttgaatg ggacagatga tcttttccat
    20161 ttccattatg aaaatgattt tggtggcgtt cgcgatgtag aaacgacttt cgaaggggta
    20221 ttgaagaata tcgagcgtcg ttatcatgat acgaacagtg atttcacgcg tgagcaaatg
    20281 cgtctttata tgacagaatt aacttgtcag acatgtaaag gttatcgatt gaatccccaa
    20341 gctctatctg ttcaaatcaa tggaacgaat atcgggcaaa caaatgagtt gtctattcaa
    20401 aaagcagtag atttcttctc aaacttaacg ttatctgaac aagagaaagt aattgccaaa
    20461 ccgattttaa aagaagtaaa tgacagactt tcattcttgg aaaatgtggg actagactat
    20521 ctaactttga gtcgcgcttc cggaacatta tctgggggag aagcgcagcg aatcagattg
    20581 gctacacaaa ttggatcgaa tctttctgga gttttgtata ttttagatga accatcgatc
    20641 ggattgcatc aacgcgacaa cgatcgactg attggctcat taaagaaaat gcgtgatctt
    20701 ggcaacaccc tcgttgtagt cgaacatgat gaagatacga tgtgggcagc agattatttg
    20761 attgacgtcg gacctggggc cggagaacaa ggcggacaaa tcgtggctgc aggcactcct
    20821 gaagaagtag ctaatgatga aaattctttg acagggaaat atctttcagg gaaaaaatca
    20881 atccctgtac caaaagaacg ccgtaaaggt aatgggaaag caatcaagat cactggtgct
    20941 tcagaaaaca atctgaaaaa tattagtgtt gaatttccat taggagaatt tgtagcagtc
    21001 acaggtgtgt ctggttctgg aaagagtaca ttggtcaata gtatcttaaa gaaatcgtta
    21061 gcgcaaaaat taaataagaa ttctgctaag ccaggtaaat tcaagacaat ttccggctac
    21121 gaaagtatcg aaaagatcat cgatatcgat caaagcccaa tcggccggac gccgagaagt
    21181 aatccagcga cttatacaag tgtatttgat gatatccgtg ggttatttgc tcaaacgaac
    21241 gaggcaaaaa tgcggggtta taagaaaggg cgttttagtt tcaacgtaaa aggcggtcgt
    21301 tgtgaagctt gtcgcgggga tggaattatt aagatcgaaa tgcacttttt gcctgatgtc
    21361 tatgttcctt gtgaagtatg tcatggtaaa cgatataatt ctgaaacatt agaagtgcat
    21421 tacaaaggaa aaagcattgc tgatattttg gaaatgacag tagaggatgc tgtagaattc
    21481 ttcaagcaca ttccaaagat tcatcgcaaa ctgcaaacga ttgttgatgt tggcttaggt
    21541 tatgtgacga tggggcaacc agcaacgaca ttgtccggtg gtgaggcaca acggatgaaa
    21601 cttgccagtg aattgcacaa aatctctaat ggaaagaatt tctatatact agatgaacca
    21661 acgacaggac ttcatagcga tgacatcgcc cgcttgttgc atgtattaca aagattagta
    21721 gatgctggta acacagtttt agtgattgaa cacaatctag atgtaatcaa aacagcagat
    21781 tatatcattg atttaggacc agaaggtgga gaaggtggag gaacgatcct tgcgactgga
    21841 acaccagaag aaatcattaa cgtaaaagaa agttatacag gtcactattt gaaaaaaata
    21901 atggtataaa gaggatagat agctgagata gttaaaaaaa cataaaaaaa tgaatttttg
    21961 cttgttttat taatatcagt gttctagaat cattacatgg tagttctttc tacactgatt
    22021 ggtatagata aaaacttcct ataagttcaa tccgttcaaa aaagaattga gcaatcggag
    22081 gactttcctt tgattgcttt tttctttatg gtatgatatt ccttgtgtag ttggaaaaga
    22141 aaaacaagag attatgagta agtgagagat aatgatgaac agtattgaaa atgaagaatt
    22201 tatccctata ttattaggaa gcgacatgaa cgtttatggt atggcacgtt cttttaatga
    22261 agcatacggc aaaatctgcc aagcatatgc ttcggatcag ttagccccta cccgctacag
    22321 taaaattgtc aatgtagaag ttattccagg atttgataaa gaccctgtat ttatcgagac
    22381 gatgcttcgt ttggcaaaag aaagatattc tgataagagt aaaaaatatc ttttgattgc
    22441 ttgtggtgat ggatatgcag aattgatctc ccaacataaa caagagctgt cagaatattt
    22501 tatctgtcca tatattgatt attctttatt tgaaaggctg atcaataaag taagctttta
    22561 tgaagtttgt gaagaatatg atcttccgta tcctaaaaca ttgatcgtca gagaagaaat
    22621 gttagtaaat ggacatttgg aacaggaatt gccttttgaa ttcccagttg ctttgaaacc
    22681 tgcaaacagt gtggagtatc tttctgtcca atttgaagga agaaaaaaag cttttatttt
    22741 agagactaga gaagagttcg atttaatttt aggccggata tacgaagccg gttataaaag
    22801 tgaaatgatt gtacaagatt ttatcccggg tgatgatagt aatatgcgtg tgctaaatgc
    22861 gtatgtagat gaagatcatc aagttcggat gatgtgcctt ggtcatccac tattagaaga
    22921 tcctacacca gcatcgattg gtaattacgt tgtgatcatg ccagattata acgaaaaaat
    22981 ctatcaaacc attaaggcat ttttggaaaa aatcgaatat acaggctttg ccaatttcga
    23041 tatgaagtat gatcctagag atggagaata taaattattt gaaatcaatt tgagacaagg
    23101 tcgtagcagt ttctttgtga cattgaacgg cttgaatctg gctcgttttg tcacagaaga
    23161 tcgagtgttc aacaaaccct ttgttgaaac gacctatgga acgaatcaat cagataaagc
    23221 aagattatgg atgggtgtgc ccaaaaaaat ctttttagaa tatgctcggg aaaatgaaga
    23281 caaaaaacta gctgagcaaa tgatcaaaga aaatcgttac ggtactactg tattttatga
    23341 aaaagaccga tcaatcaagc gctggttgtt gatgaaatat atgttccata actatattcc
    23401 aagattcaaa aagtattttc atgtgaaaga aggctagttc atggagaatt ttttcagtat
    23461 tttaggcgga atgggcacga tggcgacaga aagttttgtt cgcttgatca accaccgaac
    23521 gaaagctaca aaagatcaag aatatttgaa ttatgtctta ttcaatcatg caacagttcc
    23581 tgatcgtaca gcttatattt tagatcgatc agaagaaaat ccaatgccgt ttctgctgga
    23641 tgatattgag aaacaaaatt tattgcgacc aaacttcatt gtgttgactt gtaacaccgc
    23701 acactacttt tttgaagagt tacaagcggc aacggatatt cctatcttgc atatgccaag
    23761 agaagcagca aatgaacttg tccgtcagca tacgacaggg agagtagcga ttctaggaac
    23821 agaaggaagt atgaaagctg gaatctatga acgcgaagtc aaaaatcttg gtttcgaaac
    23881 agtgattcct gatactgcgc ttcaagaaaa aatcaattac ctgatctatc atgagatcaa
    23941 ggaatcggat tatttgaatc aagagctcta ttacgaaatc ttagaggaag cggtagagcg
    24001 cctaaactgt gaaaaagtca tcctaggttg cacagaatta tctttgatgc atgaatttgc
    24061 tgaagataat cattacccag tgatcgatgc tcaatctatt ttagcggatc gaacgatcga
    24121 acgtgcatta gctgaaagaa gcgaggcatt ggatacagca tcggaaaagt aaaaaaattg
    24181 gatttggggc aaatatccta aaagatattt ggtccaaatc tttttgtaaa agaaaaagaa
    24241 aactggtaat gatacgcccg ggatgatata attttattat gcacaatgtg agaggggttc
    24301 gtaaatatga cagataattt gcaattagtc atcataacag gtatgagtgg tgcagggaaa
    24361 acagtagcta tccaaagttt tgaagatatg ggctattttt gtatcgataa tatgccgcct
    24421 cgattgattc caaaattctg ggaattgatc aaagaatcag gtaaagtcac aaaaatggct
    24481 ttaggagtgg atttgcgttc tcgttccttc tttgaagaaa tccaaaacat gctgatcgaa
    24541 atcgaaaata cgaacttcat cgacacttct atcttatttt tagatgcttc agacgaagaa
    24601 ctagtggctc gctacaaaga aacaagacga gcacatccaa tggcgatgga cggtttgatc
    24661 actgaaggga tacgtaaaga acgggcgata ctagacgact tgaaagccca agcttccgtg
    24721 atcattgata cgacaacatt gacaccacga caattacgtg aaaaaatcaa tgagtcattc
    24781 aaatcaaagg gagaccaagg atttcggatc gaatttgtat catttggttt taaatacggg
    24841 ttgccgatcg attcggatat tgtgatggat gtgcgttttt tgcccaaccc tcattatatc
    24901 ccggaactaa gaccattgac cggaaaagat cagccagtct atgattatgt gatgtccttt
    24961 gatgaaacgc aatcattcta ccataaattt ttggatcttc tggaaactgt attgcctgga
    25021 tacattaaag aaggaaaaag cagcttgaca gttgcaatcg gctgtacagg cggtcaacac
    25081 cgttctgtgg cattgactga acgtttggca aatgctttag ggaaaaacta taaagtcaat
    25141 gtgacacatc gggacaagga taaaaggaaa gagacggtga accggtcgtg aaaatgaaaa
    25201 cctaccggat aagaaaacca aagatcgtag tggtcggcgg tggcactggt ctgccagtta
    25261 tcctgaaaag tttacgaaat caaggagcag atatcacagc agtagtgact gttgcagatg
    25321 atggtggaag cagcggtgca atcagagaat cgatcgctat ggctcctcct ggtgacttga
    25381 gaaatgtctt agtggcgtta tcggatatgc cacaattcta tgaagatatt ttccaatacc
    25441 gtttcaaaaa ggaagatcag tttttagcca atcatacgat cggtaatctg atcattgccg
    25501 cagtttccga gatgcgggga agcacttatg aggcgattca attattagca aaaatgatgc
    25561 atgtagatgg acatgtttat ccttcttcag aaactccttt gaccttgcat gctgttttta
    25621 aagacggaac gactgcagta ggagaatcta aaatcgcgat caaccgtaaa accattgacc
    25681 gtgtgtatgt ctgcaacaca aatgataaaa gtgaagccaa agcggctcga aaagtcgttt
    25741 cagcaattat ggacgccgac atggtcgttt tgggacccgg aagtttattc accagtatcc
    25801 ttccaaattt agtgatacca gaaatcggcg aagcaatgct caagacaact gctgaaaccg
    25861 tctatatctg taatatcatg acccaaaaag gggaaacgga acatttcaca gatgccgatc
    25921 atatacgtgt tttacacaag catttgaatc agccttttat cgatacagta ttggtcaata
    25981 cggaaaaagt gcctgaagat tatatggacc cagagatcta tgatgagtat ctagtacaag
    26041 tcgcacacga cttcaacgga ttgagaaatg aaggatgtcg agtgatttcc accgactttt
    26101 tagaattgaa agatggtggt gtcttccacg atggagacaa agtagtagaa gaattgttcc
    26161 gtttagtttt cggttcaaaa tattaagcaa tttattgttg gagaaaggag gagaatagga
    26221 tgtcatttgc tgcagatgtg aagaaagaac taactggttt ggaagttcat cgagaacatg
    26281 cgaaagcgga attagctgct ttgctgcgaa tgaacggctc tttaggtatt gtgaaccagc
    26341 agtttatttt gaacgtccaa acagaaaatg ctgcaattgc cagacgtatc tattctcttt
    26401 tgaaagatca ttatcaggta cgaagtgagc tactcgttcg taaaaaaatg aaattaaaaa
    26461 agaacaatgt ctatatcgtc cggttgaagc aaggcacaaa agatgtgttg atggatcttg
    26521 atatcatgga tggtatgatg ttcaatggac acgtttcgga cgagattatg ggaaattcgc
    26581 aaaaaatgcg ttcttactta cgtggtgctt ttatggcctc aggttcagtc aataatccgg
    26641 aaacgagtcg ttatcatttg gaaatatttt ctatttatga acagcataac caagacattt
    26701 gcgatatgtt aaattattac ggtctacatg ctcgaacgct tgaacggcgc aatggctata
    26761 tttcgtattt aaaaggagca gaaaaaattg ctgatttctt aacattgatt ggtgcaacca
    26821 actcaatgct ccgatttgaa gatgttcgaa tcgtacggga tatgagaaat tcggtcaatc
    26881 gtctagtcaa ttgtgagaca gcaaatctga acaagacgat tgatgcggct tctaaacaaa
    26941 tcgaaaacat cgaattgatc gaagcaaagg tcggtctaca tgcccttcct gaaaaacttc
    27001 aggaaatcgc agaacttcgg cttcaacatc cagaggtcag cttgaaagaa ttaggggaaa
    27061 tgattccctc aggtgcaata tcaaaatcgg gaattaatca ccgaattcgc aaaataaatg
    27121 aatttgcgga aaaactgcgt gaagaagcag tttaatccaa agaaaaaact gatacatgaa
    27181 gcaggagatg cgaatgtatc agtttttttt aaaagctata cttgcttttc ttccgtcaaa
    27241 ctataattcc aactttactg gagtaacata atgttgaaag gcttctattg ttttttaata
    27301 caatcgtata aaaagcgggg agacaactga atgaagattt tagttttata cataaacttt
    27361 tgcttaatat agaagtcctg atatagatag gatcaagtat ttatctataa ctggagatta
    27421 attaaaaact ggaaggaact gctcgatcaa ccttgagaac tgtttttctt acttctggtc
    27481 aagattctcg tggttggtgg ataaggatgg ttgataagtt cattggatta gctagtcgaa
    27541 aacaaccagg tgtaattaat gtagaagttt taacaagggg atggagtgat ttattcagtg
    27601 ataatcataa gttcataaat agtaattggg atgtatggtt ggtatacgtt atacctgaac
    27661 ttgaactatc aagatttggt ttagaatttg agaatcgatg tttataaagg gagggcaaaa
    27721 aatgtgcttt tttacaactt ttactatcat tatgattgca gtacttttta tttttctaga
    27781 tatagcaaag cgaaatacag catttttatt atatcgggtt ttacttcgag caggtctcat
    27841 aacatttata tcgatcgttg gattttttct attcacagtt attgtattta tttggagaac
    27901 tacagcacca ccattgccag agattacata tggagaattt ccgtttagtc ttgaatatga
    27961 aatagatgag gaaagaattt tgattgaaga tacggtgatt gcagaattta taggaagttt
    28021 tagagggaat gtgacaactc aacctagacg aagttggagt ataaaacttt taaataatag
    28081 tggagagttg aaagcatttc attatgaatt cttaataata gaaagtgaag atgtaacaat
    28141 cactttaagt agtggctctg ctggatattt tatgaatgat ggtggaagca agccacagct
    28201 cacagtccgt gatcgtattg caggttttat gcatttttct cactatgact tagaagaagc
    28261 tcgtaaaata cttgcagaat atgggatcac attaatcaat tgggaatatg cgccaccgat
    28321 aagaaatttt ttcaatgatt attattagtc ttataaaaaa cagaatgtaa aatttatgtg
    28381 cgcgagtatt tagttttcca ttttttgttt gatagatata tagcattgtt gaagcatggg
    28441 atagtggtgc caattttatc aatgaggttg gtcaggcagt taacataatt ggtgatgcta
    28501 taaatccatt taattggaat tggaggaatt aggtgtggaa acagtgagat tatggatatt
    28561 catgaaaaat tttcgttcgg ctttgagata tgttattctg gaatcaaaat caggttatta
    28621 tctgattgac acagatcact atactttttg gggaggctac ctttttccga tttttaattg
    28681 gataatcccc cataaggtta tgaaaattaa cttgcctgca gaagaaataa atagattaat
    28741 actcaacaaa gatttacaaa ggaaaagaga gaaagaacat tctaatgttg cttggatagg
    28801 tccagcattt gcagtagtga cttcttcaat tgtcggtcct atgctagaga gtatttatag
    28861 tgatttttct attggaatac gttatttatt tgttacttta agtatagctg ttcttttgtg
    28921 cataaagggt tatgttagca agaagaataa agatatttta acactaatcg gtgtaaacaa
    28981 tttatctagt actaaaatta tactgtttcc tgaatctata aaagaaggat caaggttgtt
    29041 gataattttt ataatgctta tactgttttc tgttttattt ggggtgatgt ttataga
//
LOCUS       DADVXE010000032        28130 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.032, whole genome shotgun sequence.
ACCESSION   DADVXE010000032 DADVXE010000000
VERSION     DADVXE010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.032"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(97..576)
                     /locus_tag="KB913_001526"
     CDS             complement(97..576)
                     /locus_tag="KB913_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6819894.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(649..933)
                     /locus_tag="KB913_001527"
     CDS             complement(649..933)
                     /locus_tag="KB913_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819895.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(1011..1205)
                     /gene="ssrS"
                     /locus_tag="KB913_001528"
     ncRNA           complement(1011..1205)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KB913_001528"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(1277..2563)
                     /locus_tag="KB913_001529"
     CDS             complement(1277..2563)
                     /locus_tag="KB913_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBB6819896.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            2701..3372
                     /locus_tag="KB913_001530"
     CDS             2701..3372
                     /locus_tag="KB913_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBB6819897.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            3338..3826
                     /locus_tag="KB913_001531"
     CDS             3338..3826
                     /locus_tag="KB913_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBB6819898.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            3839..4786
                     /gene="prmA"
                     /locus_tag="KB913_001532"
     CDS             3839..4786
                     /gene="prmA"
                     /locus_tag="KB913_001532"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBB6819899.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            4787..5551
                     /locus_tag="KB913_001533"
     CDS             4787..5551
                     /locus_tag="KB913_001533"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBB6819900.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            5784..7997
                     /locus_tag="KB913_001534"
     CDS             5784..7997
                     /locus_tag="KB913_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBB6819901.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            8008..8454
                     /locus_tag="KB913_001535"
     CDS             8008..8454
                     /locus_tag="KB913_001535"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBB6819902.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            8625..9884
                     /locus_tag="KB913_001536"
     CDS             8625..9884
                     /locus_tag="KB913_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBB6819903.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(9973..10920)
                     /locus_tag="KB913_001537"
     CDS             complement(9973..10920)
                     /locus_tag="KB913_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6819904.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            11314..12606
                     /locus_tag="KB913_001538"
     CDS             11314..12606
                     /locus_tag="KB913_001538"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBB6819905.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            12621..14390
                     /gene="aspS"
                     /locus_tag="KB913_001539"
     CDS             12621..14390
                     /gene="aspS"
                     /locus_tag="KB913_001539"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBB6819906.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            14499..15374
                     /locus_tag="KB913_001540"
     CDS             14499..15374
                     /locus_tag="KB913_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6819907.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            15640..17523
                     /locus_tag="KB913_001541"
     CDS             15640..17523
                     /locus_tag="KB913_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBB6819908.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(17598..17882)
                     /locus_tag="KB913_001542"
     CDS             complement(17598..17882)
                     /locus_tag="KB913_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBB6819909.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(17872..18606)
                     /locus_tag="KB913_001543"
     CDS             complement(17872..18606)
                     /locus_tag="KB913_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBB6819910.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            18735..19358
                     /locus_tag="KB913_001544"
     CDS             18735..19358
                     /locus_tag="KB913_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBB6819911.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            19550..20671
                     /locus_tag="KB913_001545"
     CDS             19550..20671
                     /locus_tag="KB913_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBB6819912.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            20678..23806
                     /locus_tag="KB913_001546"
     CDS             20678..23806
                     /locus_tag="KB913_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBB6819913.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            23825..27019
                     /locus_tag="KB913_001547"
     CDS             23825..27019
                     /locus_tag="KB913_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBB6819914.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(27165..27872)
                     /locus_tag="KB913_001548"
     CDS             complement(27165..27872)
                     /locus_tag="KB913_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6819915.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT         9369 a         5021 c         5989 g         7751 t
ORIGIN      
        1 cattataaag accgatgagt gcttgccgcg tcttttgttt ttatcacggt tttttgtgca
       61 aaaaaacctg ccgatagttg gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc
      121 tggcaattgg ttttctaaat cagttcggac aacaagcaca tcgcaagctg cgtttctaat
      181 aacatattca gaaacagaac caataaataa acgttctaca gcattcaatc ctgtggctcc
      241 taacataatc aaatctactt gattatcttc tgggatttct ctggcaataa tttgttttgg
      301 tgagccatat tctacgacag aggttacatt attcaagcca gctttcttcg cattgctttc
      361 ataatctgcc aatgtttgct ttgccatttc agtagcttgt tctgcaagca ttccatcaaa
      421 ggatgaaacg gtttggaaag aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt
      481 atttcggata gctacattga ccgccttttt aaaagctaat tcagcttcat cagaaccatc
      541 tacggcaacc atgatttttt tgtattgttg taacataagc attcactcct caagtcaatc
      601 gtattgtact cttttattgt agaacacttt agggaaaaag agaattattt actgctttgg
      661 ttcagcaatt ttttttgcaa atcggatact gaaggtggca gaaacaataa ttacgatcag
      721 taaaaagacc aaggcaataa agcgttgatt gaaaaaagct gttaaaatac ccattacgcc
      781 taaaacagca tatgcagctc cgtaaaattg taggaatcct tgatttttat catttttgtt
      841 gatcaataca aaaaagatat cctgtttatt aaataaataa tagctaacga ataataatac
      901 taaagtggcg ataatcatta aaatcctaat catgaacaaa tcctccaaaa taagcaacaa
      961 atagaaaaag caatttgcca agagcaaatt gctttattct ttaaaagatg gtaatctccg
     1021 ttaatgccgt tgtttgtcct gtagtattga tcccgcgaat tcaagcaggt gggtcccatg
     1081 gtcgtagctt cgaactacca aatgataagg catgttacca gcagtgacac aagacgggtc
     1141 ccaagatatc aataaaaatg ttcggtcaac acacaaagag gacaattcga acatcacaga
     1201 tttcccacct ctatagtagc atatgaattt aaaaagagca atgagagagc tcgcagaaac
     1261 agaaccgttt tcttgtctag ttttttggag gatgcttttt ccactctttt atacggtaat
     1321 actgttgacc cagagcctgt tcatatttcc ctgtatcttt tggctgataa tactgagcat
     1381 tcttcagttt atctggtaaa tattgctgat tgacccaagc ctgatcaaaa tgatgaggat
     1441 actgataacc cacgccacgg ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat
     1501 gatcaggaac atctccagct ttgccctctc gaatatcagc aagtgctgca tctaatgcca
     1561 tgtaggcaga attggatttt ggcgacaagc aaagatcgac gacgacgtct gctagtggga
     1621 tacgtgcctc aggcaatccc aatttttcag cagctaatac agcgttcact gtacgagccg
     1681 cagcagcagg attacctaaa cctatatctt cataaccgat aaccatcaga cgccggcaaa
     1741 tacttgccag atcacctgcc tcaactaaac gggcgagata atgaagtgca gcatccacat
     1801 cacttccacg aatcgatttt tgaaaagccg aaataacgtc ataatgagca tctccatttt
     1861 tgtcatgggt aagagctttt ctttggacac attcttcaat gatcgacagt gtaagatgaa
     1921 tccttccttc tttatctgaa ggagtcgata gtgtagccag ttccagccca ttcaatgcac
     1981 tccgcaaatc gccgttcgtt gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga
     2041 ttgcttgttg tccaaggccg cgttctttat cccttaaagc atgttcgact gccaactgga
     2101 tgtcttgttc tgttaatggt ttgacttcaa agatctgtgt acggctgcgg atcgctggat
     2161 tgatggtaat ataaggattc tcagtagtcg ctccgatcaa gatgattcgg ccactttcta
     2221 aatgaggaag cagaaaatcc tgttttgttt tatctaatcg gtgtacttca tccaataaga
     2281 ggatcactgt accactcatt tttgcttctt ccgctacaac ttgtagatcc ttttttgaat
     2341 ctgtagcggc gtttagcatg cgaaatgcat aattagtaga gccggcgatc gcacttgcga
     2401 tactcgtttt tccagtacca ggaggtccat atagaatcat ggaagagagc atgcgagcat
     2461 cgaccatgcg gcgtatgatt tttccttccc cgactagatg ctgctgacca acgacttcat
     2521 cgatcgttcg aggtctcatg cgataagcca atggctgttg cataggattt tcctccttct
     2581 tgtttttacg tcccttaatt atatcatatt tagcaagatg cctagaaaga acagccttct
     2641 gttgttttgt tttcatagct tatccaacta atattgtgta tgataaagta ggtgagaaaa
     2701 atgacggata aacaaaagat agatgaattt ttttggaata aaacgacgcc agaagtggca
     2761 cgggatttat tggggatgta tttggagcat gacacaccag aaggaagatt agctggatat
     2821 attgtagacg cggaagcata cctaggtcca gaagacgagg ccgcccatag ctatggttta
     2881 agaagaacac cgcgtgtgcg ggcaatgtat gaaaaaccag gtacgatcta cctttacacg
     2941 atgcatactc atcggatttt gaacatcatt actcagccag aagggattcc tcaaggagta
     3001 atgatacgtg caatcgaacc cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga
     3061 aaaactggtc cagatatcag caacggtccg ggaaaattag tggaagcatt agcaattcct
     3121 caagaacttt atggtcagtc tatagcagat agttcgttac gcttagtttt tgagaaaaaa
     3181 aagacaccaa aaaagatcaa tgctttgcct agaatcggta tcccaaacaa aggtgtatgg
     3241 acagaaaagc cgttgcgttt tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa
     3301 aaccaaatcg agaaagattg gggttggagg aaagaaaatg aaaaagaagg atctattaac
     3361 atatttagat gaaataattg aaaaacaagt gacagactat gatgtagctt tagattggga
     3421 tacaaaaaat catacgatcg agatcgttgt tcgcttgttt gcagaaaata aagcacaatt
     3481 tgagattgat gatgcagaag ggatcgtttc gcaagaacca attatcgaat ttgaagacgg
     3541 cgtacttctt tttaatcctc agaaatctgt ttttgatgaa cgcaattatc tagcagtaat
     3601 cccttatgaa ggaaaaaaag ggttggcaaa atcagtagct gattctttag tggaatatct
     3661 aaatgaagta ttagctcaag ggcaaagcga tttgcttgat tttttggatg aagacgatga
     3721 cgaagctgta ttcgagcttc actgggataa tcagcaacta gcagaattag tagaagtaaa
     3781 acagcaaaat gaagcagata cttatttacc gtacccaagt tattaaggag tgacagatat
     3841 gaaatggaat gaagtaaaag tagaaactga aagtgaagca gtcgaagcag ttgctaatat
     3901 tttgatggag gcaggggcga gtggtgtcgc gattgaagat tctttagatg ttgaacattt
     3961 tcagtcggat caatatggtg agattttaga taaaaatgat tttacatcgc tgaaagaagg
     4021 cgcactagtc atggcttatt ttccggaaac gactttctta ccggaaatct tgccttttat
     4081 caaagatcgt atcacacaat tacctgagtt tggtctagct attggaaaaa ataaagtaac
     4141 agttagtgaa gtagaggaaa gcaactgggc aacagcctgg aagaaatact atcatccggt
     4201 gcgtattacg cgaatgctga cggttgcgcc aagctgggaa aactaccaga cagaagatcc
     4261 tctagaaaaa attatcacac tagatcctgg tatggcattt ggcacaggca ctcatcccac
     4321 gacttccttg acattgacag cactagaaac agtcttgcgt ggtggtgaaa cattgctaga
     4381 tgtgggaact gggtcgggcg tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt
     4441 ctatgccttt gatttagacg aagtagccgt tcgttcggcg aaagaaaata tggatatgaa
     4501 tgaaatagcc aaagatgtcc atgtatcagc taacgatctt ttgacaggaa tcgagattga
     4561 aagtgatgta atcgttgcga acattttagc agatatcatc ttattgatga tcccagatgc
     4621 ttggcgttta ctgaagcaaa caggcacgct gatcgtttca ggaatcattg aagagaagaa
     4681 gcaaatggtt ctggatgcca tgttagaaca agggtttatc gtggatcaaa ttttccagca
     4741 aaaagactgg tatgcaatta ttttgaaaaa accagaggtg gaatagatgc agcggtattt
     4801 tttaaaagaa tcatatgaat caaaagacta ttttgtttta gaaggggaaa actatcacca
     4861 cattgtacgg gttatgagga tggaacccga ggatgaagtt tttttggcat tcaatgatca
     4921 aatagccatt gttgcagaaa tcacggagat tactgaagag gctgtttatc tgaaagaaat
     4981 taaaaaagaa gaaaatcaaa aggaactgcc aagttcgatt accatagcga gtggctatcc
     5041 taaaggggaa aagctggatt ggatcgttca gaaatccact gaattaggag cgcaagcttt
     5101 tcttggtttc ccggcatcag cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg
     5161 acaacaacgg cttgaaaaga ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt
     5221 gccatcagta gagttattgg aaacgaaaca agatttattt gagcggctag atgattatga
     5281 cgtggtcttg gttgcttatg aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa
     5341 aattcttagt gaaacaaaac cagatagtcg aatcttagct gtctttggac cagaaggtgg
     5401 attatcccgc gatgaagtcg attattttgt agaacacaaa gggatacttt gtggattagg
     5461 accaagaatc cttcgtacag aaacagcacc tctttattta ttaagtgctg ctagctatca
     5521 atgggaatta atgaatcctt ctttcagcta acgttcttca ttaataaaag agtatcgaca
     5581 gaaagaattg aaaaaatagt caacaatttg tataatagaa acaattattt atacaatgga
     5641 tacgaaaaat cgtttgaaaa agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa
     5701 ctgcacggat tttgggacaa ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa
     5761 aaaagaaagg gggatcgatt cctgtgacaa aagaagaaat tttaacggga cccggtgtca
     5821 taaagctcgt tagtcaatac atgggtcccg aacatgtagc atttgttgag aaagcatgcg
     5881 aatacgcgac tgctgcacat gacggacagt ttagaaaatc aggcgaaccc tacattattc
     5941 atcctatcca agtcgcaggt atattagcag atttaaaaat ggatccccat acagtggcta
     6001 caggcttctt acatgatgtt gttgaagata cagaaatcac tttagaagat ctgagagaag
     6061 aatttggcga tgacgttgct atgttagtgg acggcgtaac caaattaggg aaaataaaat
     6121 ataaatccca cgaagagcag ctagcagaaa accaccgaaa gatgctgcta gcaatggctc
     6181 aagatttacg agttatcatg gtcaaattag ctgatagact acataacatg cgtacgttga
     6241 agcacctgcg agaagataag caaagaagga tcgctcagga aactttagaa atctatgcgc
     6301 ctcttgcaca tcgtctaggg atcagccgga tcaaatggga attagaagat acagcacttc
     6361 gttatctaaa tccaaaacag tattaccgta tcgtccactt gatgcagacg aagagagaag
     6421 aacgtgaaaa atacgtaagt ggtactgttg aagatattcg aatagcgaca gaagagctgg
     6481 ggatttttgc agaaatctat ggacggccaa aacacattta ttcaatctat cgtaaaatga
     6541 aagatcagaa aaagcagttc aacgaaattt atgacttgct agctattcga gtgatcgtag
     6601 attcaatcaa ggattgttat gctgtattag gagcaatcca cacaaaatgg aaaccaatgc
     6661 ccggcagatt taaggattat attgccatgc caaaagctaa tatgtaccaa tctttgcata
     6721 ctaccgtgat cggtccggca ggaaatccgg tagaaattca aatccgaaca caggaaatgc
     6781 atgaaatcgc tgaattcggg gttgctgcac actgggccta taaagaagga aaaaatgaaa
     6841 aagtagaacc agatggtatg acgaaacaat taagctggtt ccatgagata ctcgaacttc
     6901 aagacgaaag ctatgatgct tctgaattta tggaaggcgt aaaaggagat atctttagtg
     6961 ataaagtcta cgtcttcaca ccaaaaggag acgttactga gttaccaaaa ggatccggac
     7021 cattggactt tgcatacagt atccatacag atatcggtaa caaaaccact ggtgcaaaag
     7081 taaatggcaa aatggtgcag cttgattaca aattgaaaaa cggagatatc attgagatca
     7141 tgacttctcc aaattcattt ggcccaagtc gcgactggtt gaaattagtt gctactagca
     7201 aagcaagaaa taagatcaaa cgtttcttca aagcccaaga tcgagaagaa aatgtgatca
     7261 aaggccacga atccgtggtc aaatgtatta cagatctagg atttacgcct aaagatattt
     7321 tgacgaagaa caaactgcaa gaagcactcg atcgttttaa ttatcaaaca gaagatgatc
     7381 tctatgcagc tgtagggtat ggagaagtta gccccttgac gatggccaat cgtctgactg
     7441 aaaaagaacg taaagaacaa aaaatcgagc agcaaaagca agaagcagaa gaaatcatga
     7501 atcagccgaa aaaagaacct gacaaaatga aagtacgtca tgaaggtggc gttgtcattc
     7561 aaggggtaga aaacttacta attcgtatca gtcgctgctg taatccgatt cctggtgatg
     7621 atatcgttgg ttatatcact aaaggcagag ggatatccat tcatcgtcga gattgtccga
     7681 atgttcagcc tgacaaacca aatgtagcag aacgtttgat tgaagtcgaa tgggaagata
     7741 catcgaatac acgaaaagag tatgatgcag atttggaaat ttacggctat aatcgttcag
     7801 gcttattgaa tgatgtactt caaacagtca atgcgctaac gaaaaatctc aacagcgttg
     7861 aagcacggac gaataaagat aaaatggcga cgatccattt gacggttggt atccagaatt
     7921 tatcccacct aaagagtatc gtggataaaa tcaaagcagt acctgatgtc tacagtgtac
     7981 gccggacgaa tggataggag gacagatatg agagcagttg ttcaacgggt aagtaaagct
     8041 gctgtgtcag tcgatcagca agaaattgga aaaattggct acggcctact tgttttatta
     8101 ggcattcatg aaaccgatac gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa
     8161 atgcgtattt ttgaagatga acaaggaaaa atgaatatta gtgtagaaga tgtgggagga
     8221 caaattttaa gtatctctca attcacactg tttgcggata cgaaaaaagg aaatcgacca
     8281 agctttgtgg aagccgcacg accagaaaca gctattcctt tatacgaatc attcaatgaa
     8341 ggaatcagaa gtcgcggcat cacagtcgct accggacaat tcggagcaga tatgtcggtt
     8401 tctctcgtca atgatggacc tgtaacgatc attattgatt ctaaaaacaa ataaagtaat
     8461 ctggttttca ctagtaaaaa ctatgaaaca cgtcgcttaa gttagactga taaactctaa
     8521 cttaagtggc ttttttgtct gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt
     8581 aagcttaaat tatacaagtt attttttata ggaggttgct gaagatgaaa gaagtaccag
     8641 tagtagatat caaaatcaca gatttaaaaa aattgtatca aaaaggatac aacatgttgg
     8701 aggagttacg ccatgaagcg gacgctcccg tcgtcaaagc aaagattttc aataaagaag
     8761 ctatcacgat ctacggatca tcagcagcaa aagtatttta tgatccaagg aatttcaaac
     8821 gaaaaggtgc tatgccaaaa ttagtattga agacactttt tggtcaaggt ggagtacaga
     8881 ctttggatgg agctgctcat caccatcgga aaaatatttt tatggatcta atgacaccgg
     8941 aaagaatgga agattatcat cgtatcttag ataagaatct gacacaagca cttgaagcac
     9001 agcatggtca atttgaacta tttgatttaa gtaagatggt tttctttaca tctatttgcg
     9061 agtgggcagg tatcaattta tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat
     9121 atcaaatctc tatgatcagc ggaacgttta cttctccgat tgatcacata aaaggtgtcg
     9181 aaaatcgcaa aaaatcagaa aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc
     9241 ctgtggctgg aaaagaaaat gtggcattat atgcttttgc caatgccaca gatttagatg
     9301 gtcagctttt acctctggaa gtggcagctg ttgaattatt gaacatcatc cgtccaacgg
     9361 ttgctctaac tgtgtgggcg gcattgatgg gacatgcact tttcagtaga ccagatttgt
     9421 atcagcaatt aaaaaatgac ttttcgacgt tacaagatcc gtttattcaa gaaatgagac
     9481 gctattatcc tttcttccca atgctacctg cgatttcgct gaaagaagta gaagtagatg
     9541 gttatcgtat accagaaggc agttgggtta ttttagattt atatggaaca gaccatgatg
     9601 aacgaacagt tgaagcgcca gattccttta tgatcaaacg gtatgtaggg aaagcaaaag
     9661 atatttccta taaagaagaa tatgagatga ttgcacaagg cgggggaaat tttcgacaaa
     9721 tgcatcgctg tgcaggagaa tggatcactc ttcatagtct acgtgtgttt tccgatcagc
     9781 tagtaaataa gtttgagttc tctgtacctg aacaagattg gacgattcca ttcaatcagt
     9841 ttccgactta tccgaatagc cgagcgctac tttacaagaa ttagattagc ataaacttat
     9901 cgaaaaaaag gaagatcaaa cagtgctgat cttccttttt tcatattact ataaattgat
     9961 aaggtcaatt gatcaaaatc cacgaaatgc ttcatcaatg gtttgataat cttcattgga
    10021 taaatgcaaa tctaaagctt ggacattgtc agatacttgc tctggacgct tagctccagg
    10081 tataactaca gacactcgtg gattcttcat gtaccaagct aaaacaagtt gcgcaggagt
    10141 ggcttggtat cttttagcaa tggggcgaag tacatcgaca gcggttaaaa tttctctgaa
    10201 acgttctcct tggaaatctg gatttctttt tcgaggatct ccttcaccaa attgtttttc
    10261 ctcaccaagt tcatattttc ctgtcagcaa accggaagca agaggaaaat agggaacaaa
    10321 actgattttg tttttttcaa gataagggaa taattctttt tcagcctgcc gatggatcaa
    10381 actgtattta tcttctacta catcgacata tccatctgca ttcgcttctt tcaattgttc
    10441 taacgtgaag tttgacacac cgactgctcg gatttttcct gcttctttta attcgtgcaa
    10501 tgtagcaact gattcatttt ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc
    10561 gatgtaatca gtttgcagac gttttagtgc atcttccacc gattgtttga gaaactcagg
    10621 agaattatca aatgttcgcc ctttatttgg tacatgagca gcttttgtag cgatgacgac
    10681 acgtgagcga tcatattctt tttccttcag tacctcgcca atcagttctt cggaacggcc
    10741 gtttccgtaa gcataagcgg tatcgatcaa attgatcccg ctattcaaag ctgtacgaac
    10801 tacttgtttt cctgtctcat cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt
    10861 tgctcctaat ccaagctgtt ctgcgtagac ttgtgaatgt ccgattctta tttctgccat
    10921 agctgattcc tcctttttgt ctagtctaaa acaaaatacc aaaaagctga actaaaacgt
    10981 ttttgtgagg ggaaatagtc agatatctct tgactttgag actggttttt agtaggttat
    11041 aagtaatatc gaatgtcaat gaaagagcga gtaagttttt gaaactttac aagagaggat
    11101 catcgaggct gaaaatgatc taaagtttca ttagcctaaa gacactctgg agatggacga
    11161 gtgaaaagcc gtcccgcgta cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat
    11221 taggtggtac cgtgtatgaa tttcattcac ccttgttcat gatgaacaag ggtgattttt
    11281 ttatttacat agctaagaaa gggagagaaa actatgagtt tccaaagacc aaaaggaaca
    11341 aatgatattt tgccaggcga atcagaaaaa tggcagtttg tcgaagaaac agcacgttta
    11401 ttattcagag attatcagta taatgaaatg cgtacaccga tttttgaaca ctatgaagtg
    11461 atatcccgaa gtgtagggga tacaacggat atcgtttcaa aagagatgta tgatttttat
    11521 gacaaagggg aacgccatgt gacgcttcga ccagaaggta cagcaccaat cgttcgttct
    11581 tttgttgagc ataaattgtt cggcccagag tatgcgaaac cgttcaaaac tttttatatg
    11641 ggaccaatgt ttcgctacga acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc
    11701 ggagtagaag catttggatc agaaaaccct gcaactgatg tggagagcat ggtgatggca
    11761 cttgatttct tcaaacagtt ggggatcacg caaatccggc tagtcatcaa ttcattaggt
    11821 gataaagaaa cgcgtcaagc ctatcgtcaa gcattgatcg actatctttt accttttgaa
    11881 tcagagctga gtgaagactc taaacgccgc cttcatgaaa atccattacg cgtattggac
    11941 agtaaagaca aacgagatca aaaatttgtg gcagaagctc catctatctt agattatcta
    12001 agcgagcctg ctcaaaaaca ttttgatacc gttgtttcca tgctggatgc attggctgtt
    12061 ccttatgaaa tcgacagtaa tatggttcgc ggactagatt attacacaca tacgattttt
    12121 gaaatcatga gtgacgcacc aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt
    12181 tatgacaatc tagtggaaga actaggtggt ccttcaacac ctggcttcgg atttgcaatg
    12241 ggtatcgagc gattactctt gactatggag gcagaggaag tagttatccc tgcatttaat
    12301 gagttggatg cttacgtggt cgcactcgga gacgaaacaa atatcgaagc attgaaagtg
    12361 gtccaagcga ttcgaaactt tggtttttca gctgaccgcg acttcatgaa ccgtaaagca
    12421 aaagcgcaat ttaagacagc agataaagcg aatgccaaat tagtattggt gatcggtgaa
    12481 gatgagcttg ctagtcaaac gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt
    12541 tttccattag aagagatata tgaacatttt gatgaagtct atgatgaaat gactttattc
    12601 gagtaggagg aaaaaaataa atggcacaaa gaacgatcta ttgcggatta gtttccgaac
    12661 aacaattaga acaaacagtt acattaaaag gatgggtaca aaaaagacga gaccttgggg
    12721 gagtaatctt tatcgaccta cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg
    12781 aaatcaacaa agaagcatgg gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag
    12841 tgactgggga agttagaaga cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg
    12901 aattcgaagt gattgcaagt gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc
    12961 aaattgaaga tgatcaagca atcagtgacg aaatacgttt gaaatatcgt tatttggatc
    13021 tgcgtcgtcc aaaaatgact aaaaacatca aattaagaaa tgcgacaaca aaagcgattc
    13081 gtcattattt agatgataat gactttctcg atatcgaaac accttaccta gggaaatcta
    13141 caccagaagg cgcaagagac tacctagttc cttcacgtgt ccatgctgga catttctatg
    13201 cgttgccgca atctcctcaa ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt
    13261 attatcaaat cgttcgttgt ttccgcgatg aagatttacg tggagaccgt cagcctgaat
    13321 ttacgcaagt agatattgaa acaacgttct taacagcaga agaaatccaa acttacacag
    13381 agggattgat tgcgaaggta atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc
    13441 ctcgtatgac ctatgatgaa gcaatggctc gctacggcag cgacaaaccg gatacacgtt
    13501 ttgatatgga attgatcgat ctaagcgata cagtcaaaga agtagaattc aaagtcttcc
    13561 aaatggctct tgaaaacggc ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc
    13621 gctactcacg aaaagacatg gatcagttag gtcaatatgt aggacaattc ggagctaagg
    13681 ggcttgcatg gctgaaagta gaagaagacg gattgaaagg tccaattgct aaattcatgg
    13741 gagaagcaac agaagcaatc attaaagcaa cagatgcaaa accaggtgac ttgctgatgt
    13801 ttggcgcaga taaaagtgaa atcgtcgctg ctgcattagg tgctatccgg acacgtttag
    13861 gaaaagaatt aggactaatt gatgaatcga aattcaattt cttatgggta actgattggc
    13921 cacaatttga attttcagaa gaagaaggtc gatatgtctc tgctcaccat ccattcacga
    13981 tgccaaaaga agaagatatc ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag
    14041 cttatgatat cgtcttgaac ggttatgaac taggcggagg ttctatccgt attcatactc
    14101 gtgagcttca agaaaaagta ctagaaactc taggctttac aaaagaacaa atggaagaac
    14161 aatttggttt cttgttaaca gctttagatt acggattccc tccacatggc ggtattgcat
    14221 taggattgga ccgttttgca atgttattag ccggagaaga taatattcgt gaagtcattg
    14281 cctttcctaa aaacggaaaa gcagcagatg tgatgagtga tgcaccaagt atggtttcgc
    14341 ctttacaatt gttcgaattg aatattgatg taacgaatat agaagaatag ccgataaaaa
    14401 ggtaaaaagg atttgtcgaa tacgcttctt ttgacaacct tgatttaatt gaaaaacact
    14461 ttataatgaa gccataacat ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt
    14521 gggcttatca tgattacacg accaagcttt cggtatctat cgtttatgcg ttgatcgcat
    14581 cagtcgcatt gaatttcttt tatcagccag gacatattta ttcaagtggt attactggtc
    14641 tagctcagat tttgacgact ttgtcaaaat cactgatagg attcgaagta ccggtatcaa
    14701 caactttgta tttactgaat atacctttgt ttgtattggc gtggttaaaa atcgggaaga
    14761 agtttacaat tttcactttt atcacagtca ctttgacctc cctttgtatc catattttac
    14821 cggaaacagt cctatctacc gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg
    14881 gactaggtat tgggctagcg ttgagaaacg gcctatcatc gggcggtcta gatatcgtga
    14941 gtatcacgat tcgtaaaaaa acaggaaagt cgattggttc tatttcgatc tacttcaatg
    15001 cattgatcgt ttttgttgcc ggaattctat ttggctggca atatatgttt tacagtacgt
    15061 tgtctatttt cgtcagtgga aaagtaactg atgtcgttta tactaaacaa aagaagatgc
    15121 aggtaatgat cgtaacgaaa catccagaaa aagtagtaaa tgaaatccaa aactgtatgc
    15181 gtagagggat cacgatcatc aatgaagcag aaggtgctta taagcatgat aagcagacag
    15241 tattgatgac gatcgttaca cgatacgaac tgcctctact tagagaagca atgaaagctt
    15301 ctgatccaca agcttttgta agtattgcag aaaacgtcca gatacttggt cgtttctatg
    15361 aggatggcat ttagatcgag tttgacaaaa attcatgaaa tactgctgta gacagacgtt
    15421 cgtttgtctg cagttttttt ctaccatagt agaatcagca aagaaaaact gcttttttat
    15481 ttgaaatttt cttaaagttg aaaaaaagca tgtttatttt tttaaattta tgggatgata
    15541 gaaaaaaata gtagagaaag gacacgattc tacttgctat tttcacttaa tacccgtata
    15601 ttacgaatga aaaaagttta tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta
    15661 aaaaacagcc gctacatcac tgggtttgat gggctccgtt cattagctgt ggtgggtgtt
    15721 atcttctatc accttctgcc aactagtatg aaaggcggct atttgggcgt tccgattttt
    15781 ttcgtcgtat ctggttattt gatcacggat ctgctgcggc aggaatggga acaaaatgga
    15841 aaaatcaata tttggcaatt ttatgtcaga agaatgaaga gactctatcc ggcacttgtt
    15901 tttatgcttg tgacagcttc ggcttatatc actttgtttc agcgagggct gttaaacaat
    15961 cttcgaggag ttgtggtcag cagcttactg tatgtcaaca actggtggca aatcaataac
    16021 ggtttatctt atttcgatcg atttgctaat gagtcaccgt ttacgcatat ctggtcttta
    16081 gcagtagaag gtcaaaacta tttggtttgg ccgatcttgt ttgtattgtt gatggtattt
    16141 gttcgtaaaa gaaaatggat cttttatact gtgttaggta catccttcct ctccgccatc
    16201 ttgatgatga tcttgtatac accaggaggc gatccaaccc gtgtttatta cggtaccgac
    16261 actcgtctgt tttctatatg gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt
    16321 ttaaagaaaa acatcccgaa acaagcgaaa aatattctga atatcgctgg aggaatctcg
    16381 cttttggcac tgattctttg cttcttcttt ttagatgatc attacaattt catctattac
    16441 ggaggaatgc tcctagtgag tctgttatgc gtagtgctag ttgcagtgac agcacacccc
    16501 ggagcaagtt tgaatcgatg gctgacaaat ccagtattta cttggattgg caaacgaagc
    16561 tatggcattt atctgtatca gtttccagtt atgatttttt atgaagcaaa ggtgactgat
    16621 attgccgatc atgttttgtt gcatacttta gtggaaatca cattgattct aatcatcagt
    16681 gaactttctt atcgatatgt ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc
    16741 caagtgatga aaggatggtt cagcaaaccg atcatcagta agagcaaacc atgggttgtt
    16801 ccaggcacat tacttgtagc aattgcactc gttggtttcg ttacggcacc gaaaaacgct
    16861 gtaacagccg atcaaaaaca actgcaggca aaaatcgctg aaagtaaaaa attagcagaa
    16921 gaaaccagaa acaattcaga aaacaccact agttcggttg accaagcgat ccttgataag
    16981 tacgagttgt ccaaggcaca agggaataag gcacaaaaat tagaactaac ggcatttggt
    17041 gattcagtta tgttggatgc tgcaacggat ctacaagaac tttatccaaa agtagtggta
    17101 gatggagatg tcggacgaca attatatgcc agtgtaccgt acattgaaaa attaaaggaa
    17161 caagatttgt tgaaagacac tgttctgatc ggactaggaa cgaatggctc attctcggaa
    17221 gctcagtttg atagtgtgat ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc
    17281 cgagtaccga cgaagcgctg gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa
    17341 aaatacgaca atatgacgct gattgattgg tacagctaca gtaatgacca tagtgactgg
    17401 ttttatgatg atcaagtcca tccaaatcct gaagggatga cacattacat tcacttagtc
    17461 agcgaagcct tgctaggagg aagttcaagt acgaacagca gtgagacaaa cgtgacagaa
    17521 tgatagctac aaaaaacttc aggcaaaaac atttgttttt gcctgaagtt tttttatatt
    17581 taccgtgttt ttaacattca tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa
    17641 taacgttctt tttgttttcg ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg
    17701 cttcttgaag aaaatacttc tgcatggatc atcttaacag gtcttctttt ttgaagacga
    17761 gtatatttag caccagtacc attgttatgt tcctctaatc gtctagaaag atcggttgta
    17821 tatccaccat aaaatgtctg atctttacag aataatacgt aaaaataatg ttcatttgcc
    17881 atagagcatc tcacgaatct ctgcagtgta ttctccatcc atattgtaag tgatcaatgg
    17941 tggagcgact ttgaatccgt ctaatttgcc ttctttgatt ccttcaacta acaaaatatt
    18001 tgcctctttt ccaggttttg ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc
    18061 ttccatgacc tgaatgattt ctaagaaccg atcaggacga tggaccatag taaagcgtcc
    18121 atttgttttt agtagcttac ttgaaatatc gatcacttct tctaacgtcg tatgaatctc
    18181 atgacgggcg attgccaggt gtttattagg gttcgtttta tttgttggca gccctttgaa
    18241 ataaggtgga ttacagacga ctaagtcaca agaattatgt cgaacgacag ataagctgtc
    18301 tttcagatcg atggtgtgga cagtcatttg ttcatttaaa tggttaagcg cgatactacg
    18361 tcttgccatg tctgctagac gaggttgaag ttcgatagcg tcgatagccg cctgggttcg
    18421 tttacttaaa aaaagtccaa ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt
    18481 tttaggtaca cgggaaaagt gagcaagcag cacagcatct aaagaaaaag aaaacacttt
    18541 ggaactttgg ataatcttga tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg
    18601 aagcatggat tccctccaaa atgaaaaaaa tagtcgtctg tattatacta tttttattaa
    18661 aaagaaccaa ggtggcttgt caaacctcta ttttttatgc atactatgac cataagaagg
    18721 gaaaggaaga gactatgttt tatcgattta tgcgcggggt agttcgagta ctattagcct
    18781 tagttaatgg aaatgcccgc tatgagaata aagaagtttt accgcaagat gagaattaca
    18841 tactagttgc tccccatcgt acttggtggg acccattata tctggcggta gctgcagcac
    18901 ccaaggaatt cagctttatg gcaaaagaag aactgttcaa aaatccagtt ctgcgattta
    18961 tattaactcg atccaatgct tttccagtta aaagagaaaa tccaggacca agcgtcatta
    19021 aaacacctgt aaagattttg aaatcgacaa atttgagttt gatcatgttt cccagtggga
    19081 caagacatgc tacagaactt aaaggcggaa tggcattgat ttccagaatg tctaaagcga
    19141 aaatcgtgcc agctgtatat caaggtccgt tgacacttgg ggatctgttc aagcgtcaga
    19201 gagtgacagt gcgtttcggc gaaccaatcg acttatcaga tatcaagaaa acggataaag
    19261 aaggtatggc ggagatcgaa cgacgaacac aagcagcttt tgacaaattg gacaaagaag
    19321 tgaaccctga tttcaaatat gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc
    19381 ggtcttttga atctactgtc ctgttcagtt cagacttttt caatgaaaac gagggagaga
    19441 cgtcaagtct gccctctttt tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa
    19501 tggatcaaag tgttataata attagaagga cattttttga ggtgattgaa tgcgtttttt
    19561 acatacagcc gattggcata tcggaaaaaa actacaaggt tatgacttga ttgaagacca
    19621 gcgtcatgta ctatcttcta tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt
    19681 gattgccgga gacttatatg ataggagtgt cccagctgtt gatgccgtag aattatacaa
    19741 tgaattgatg gtcgattgga atttaaagga aaagatcccg atttttgcta tatcaggaaa
    19801 tcacgatagc agtacgagac tttcagcggg tacgccatgg ttcagttatt cgaactattt
    19861 tttgcgaaca cagctagcag aagcatttga accagtcgag tttaaaaacg tacaattttt
    19921 ctttcttcct tactttgaac caattgcagc gagattatat tttgaagatg acaatatccg
    19981 aacgatcaag caagcggtag ccaaggtgat agataaaatg caggagctat ttgattcaga
    20041 aaaaaaacaa gtattgatta gccatttttt tgtaatggga agtgtaaaat ctgattcgga
    20101 aacgaaaatc gaagtaggcg ggttggattc gatccctggt gaactactta caccgtttga
    20161 ttatgtagca ctaggacatt tgcataatca agctgctttg agacaggata atgctcgcta
    20221 tagcggttcc ccattgaaat tctctttatc tgagatcaac caaaaaaaag gcgtatggat
    20281 cgttgacctg acaacaggcc tggagttgaa ttttagggag atcgaacccc tgcatgatat
    20341 tgaagaaata acagcgagtt tcaaagaatt gctggatcct gccttttatc agtccgtcaa
    20401 tcgggagaat tacatctata tctatctcac tgatagaacg atcatcccga atatgatgaa
    20461 ccagcttcgg caaatatatc ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga
    20521 acaaacaaag cgcaaacgaa aagtactaga aatgaaagat cctcaaaaat tagcagaagc
    20581 attttttagt gaaatgacgg aagagcagct aactgcaaac caagaaaaat ggctcggaga
    20641 aacgttgcaa gaaatcatgg aaatggaatg atcaagaatg aaaccgaaaa aattacaact
    20701 taaaaatttt ggtcctttta tcaatgagac cgtagatttt tcacgtttga cagaagcacc
    20761 gctttttttg atcagcggga agacaggagc tggcaaaacg acgatttttg atgggatcac
    20821 cttcgcactt tttggtgaaa cttccggaag acttcgctct ggaaaagaga tgcgttcttt
    20881 gtttgctaca ccagacgaag aaacaagcgt gactttttct tttgaacatc agcagatgag
    20941 ctatgaaatc gaacgaaaac cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa
    21001 aaaacaggca gccaaagtaa cgttgaccat ttttgatggg aaaggaaaag aaataaaaca
    21061 aatcacaaaa cgtacagaag cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa
    21121 acagttttct caaatcgttt tactacccca aggagaattc cgtaattttt tggtttcatc
    21181 aagcagtgat aaagagactg ttttacgtca tttattcggt actcaatttt tccaacagtt
    21241 caatgagcga ttaaaagaaa aagcaaaaca acagcaacaa aaattggatc atttagagca
    21301 agagctgcat cttctgcaaa aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg
    21361 gtttgaagcc gttttagccc aatggacaaa ccatcaggca atactcgaaa aacaaatcac
    21421 ggaagaaaaa gaagctctaa cggaacttca ggaaaaacaa aagcaactag aaaattccta
    21481 ctatcgtttt gaaagcttga aaaaaagtta tgaagaaaaa acgatattaa taaacaagca
    21541 aaaggaatta gctgctcaaa aagacgaaat agaggaaaag aaacgatgga ttgggtatta
    21601 tgaatttacg caacgattag tcgaaccaat ccagcgccta caagaaataa aagttgaaaa
    21661 aatagaactg tcacaaaaaa gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa
    21721 ttatgaagag tggcaaaaaa atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga
    21781 agctgctcaa aaactgcaaa acaaacagat gatggtgcca attgtcgaat ccttacgtag
    21841 taaaaaacaa gacgcagaac aattaacaat ttcattggat aaagaagaat tgaatgccga
    21901 gaagctgtat caaaatctcg ctatctatca ggaaagaact cgaattcttc aagaaaattt
    21961 actggatcag gaaaaactgc aagaagatcg tcttgctttt ggacagttaa aatatctaga
    22021 tgaaaagcag caagaaatag aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat
    22081 aagagaagaa ctcaaaaaag caactgaaga aataacaaaa aatagtcagc tattgaaaga
    22141 acagacagaa caagcagaac agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct
    22201 tcagcttttt ttgcgtccag gggagccatg tcttgtttgt ggatcaacgg aacaccccat
    22261 acaacaatta aaacacgaac agccaaataa ggaagatatc ttaaaagtag aacaacaact
    22321 ggcagaagct gagtctgctg tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca
    22381 tgaaaataat cttcaacaac aattatcaga tttagaacaa aaaatcatgg caacgaatat
    22441 acaattggct gaacaagaag aacacttgca acaggctttg aaaaaggcat ttcctgagat
    22501 aacagaacaa aaaacaaaaa caactcttgt agtaatcgaa caatctttag atagacgaaa
    22561 aagcaagatg gccaatgcaa gaatagagct ggaagaaata agacaacaag cagaaaagct
    22621 cgaacaacaa ttagctgtct acaaacagca gcagacagaa aaaaataatc agctccagca
    22681 actgcaagga gaaatcaaaa gtttagaaca acaattgcaa gatacggata gtaactgttt
    22741 agaagaggag atacgacgac ttgaaaaaca gttagaagaa gactcgaatc aactagctgt
    22801 tgagcagaaa gcaggagtgc aattgttgca agatcttcat acgcttcgga cacagcttga
    22861 tcttcaacat gaacaaatag aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat
    22921 agctaaaaag ttagaaagcc agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc
    22981 acaacagcaa gcacaatata aagaaaacca acgtacagtt acttcttatc atgaagagca
    23041 attagtgaca gctgaccggc tgcgtcaatt agaaaatatc cagctaactg agacattccc
    23101 agatacagaa gagatcagcc aacagttaga agaaataaga cgtatgatcg aaataaagca
    23161 agaaaagata tacggtttac aagaacaaaa aattagtaat caaaaaatct acgatgaatg
    23221 tctttcgatt tatcacacaa gccagacgaa attagatgag cttacgcaat tacagcagct
    23281 ttcgcaaaca ttcaacggag aaaatcctaa gaagactagt ttggaacggt atgtgcttca
    23341 ggtttatctt caagaagtgt tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa
    23401 tcgttatcaa tttgagctag cggataccat tggcagttat cgagggaaaa ccggattaga
    23461 aatcaatatc tatgatgatc aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg
    23521 tgagagtttt attgcagcac tttctttagc attagctctt gccgatgtga tccagacaca
    23581 agctggtggt gtagcaatcg atgcattgtt tattgatgaa ggatttgggt cattagatga
    23641 agaagctttg gaaatggcaa tggaagcttt agaaacgatc gaaagtgaag gaagaatgat
    23701 cggcatcatt agtcatgtaa gagaattgaa agaacgagta ttacaacaaa taagaattga
    23761 tacagaaggt agcggacaaa gcaaaatacg ctatcaactt ggataaaaag ggagattggt
    23821 aactatgaaa tggagtattc cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga
    23881 aggccgagtg ttatcggttg tccctgacca agaagaaaac gtgtggcatg cagaagtctt
    23941 gggcagtgaa ttgtatatgg ttgatttgga tggtacagca aaagagatag attactgcca
    24001 atgtccctat tgggaggaac ataaatattg taagcataca gttgctgtgg aactttattt
    24061 acggtcgaaa aatctatctc gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa
    24121 agcaacaagt gagggagaaa tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa
    24181 tcctcaagcg gtgcaacctt tgattattga ataccaagta gaaacgattg agactaatca
    24241 gtatcaccca gagctttcta ttttggcact ttacttgcgt atcggttcat tggcatcacc
    24301 gaaaaaaaca tatatcgtaa aaaacatcta tgatttttta caagcttaca cagaaaaaga
    24361 aacttacact gttaataaac agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga
    24421 agatcaaaaa atactcacgc atcttgcagg aagtgctcag acgcatcaat tattaggtac
    24481 gaacggctta caagtcaaag gaaaactaga taaaagatat ctgcttctcc cagtagaaca
    24541 agcccgcttc ctgttagagc agatgaatca gactacacgt ttgcatctgc agataaatga
    24601 acaaaacgat caaggaatac aattttccga tcaaaacaaa cctttatcat tcaaagtgga
    24661 aaaatttgga gaagattatt tgctgcaagc attgaatgat tttgattttt tctttatgca
    24721 ttatcagtgg ggagttatcc aagggacatt ttattctctg acgaaatatc aacaaacggt
    24781 ttatcaaact tggaaacaat tgattcgccg attggagaaa ccagaagtag tgttcaagaa
    24841 aaaagaatta ccgtctttgt ttaaagagat tatccctctg ctgtcagaga tcggcgacgt
    24901 agctattgcc cctgcagtag aagaggaagt agcagatatc cccgtcgaat ttattttctt
    24961 tttccgaaaa gcaaaaggaa aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat
    25021 ctattcgact gacccgaagc atgaggtctc gacagaacag gcttttcagg tgttacgtga
    25081 cacagtagaa gagaaacgag tacttgatct attcagaatg tatcgctacc agaaaaatga
    25141 aactggttat gaacgtccat tgccaagcgg ggaagaacta tatgcctttt tccgcacaga
    25201 actatctgtc ttccgtcagt ttggtgaagt cagacttgga agaaaattgc gagagttgta
    25261 tttagatgcg cataaacatc aaccgaaaat cgaagtaacc gagaccggtt catggctcga
    25321 tattcgattc gatgtgacag ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt
    25381 gctgagaaat gatgcttttt atacattaga aaatggtcag gttctttctt ttgattcaga
    25441 agaatttcaa caaacaagcc aagtgttgca acaattacgg gaatcgatac gtacagaaga
    25501 aggaacgatc catgtaccta aaaatcaagg attgatcatt caaaatcaat tggaaaaaag
    25561 caatgctact tttagtgaat cgttccaaac gatggtacaa gatctcattc atccagaaag
    25621 ataccaggca cagcttccca aaggattgaa tgcaacgatg agagattatc aaaagcaagg
    25681 ttttcgatgg ttgaagatgt taggtcatta tcagtttggc ggtattttag ccgatgaaat
    25741 gggacttggg aaaacactac agacaattgc ctttttactt tcggaaaaag aagaacggaa
    25801 aagcttctct gctttgatcg tagcgcctgc gagcttaatt tacaactggc aggcagaggt
    25861 gagaaaattc gccccttctt taagtatcca agtaatcaat gggaataaaa aagaacgtga
    25921 agaattactg gctaaagaca cagatatccg agtgacttct tatgccagct taagacagga
    25981 tctagctaat tatcagtcgc aaaaaattga ttatttgatt cttgatgagg cacaaatggt
    26041 caaaaatagc agtacgaaaa ctgcacaagc attgagagaa ttagctgtac ctcagcggtt
    26101 tgcactgagt gggacaccaa tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac
    26161 gattatgcca ggatttttcc cgactaaaac aaaattcagg gaacttgccg cagaagaaat
    26221 tgcgcaaatg attcgaccgt ttattttacg gcgagataaa caaactgtgt tgaaagactt
    26281 gccggaaaaa acagagatga atctatattc tgcacttaca gaagaacaaa aaactgttta
    26341 tttagcttac ttgcgtcaaa tgcgtgaaga aatcacatca atggattctg aagcattcaa
    26401 gaaaaaccgg atcgggatac ttgctggtct gacaagactg cgacaaattt gctgcgatcc
    26461 tcgtctgttt attgaagatt accaaggcgg ttccggcaag ctcgaacaag taaaagatct
    26521 actggtagct gccaaagaga acaaacgaag agttttgctg ttttctcaat ttacagggat
    26581 gctgactatc ttgcaagaag agttagccga gctagggatc tcgacatttt atttaagagg
    26641 cagtacgaaa ccacaagatc ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga
    26701 tgtttttctg atttccttaa aggctggggg aactggattg aatctcacgg gagcagatac
    26761 ggtcatcttg tatgaccttt ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc
    26821 acatcggatc ggacaaaaaa atgtggtaga agtgtggcgt atgatctctg aaggaacgat
    26881 tgaggaacgc atggattcac tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca
    26941 aggtaatgaa gaacagttga cgaaactgac tgaagaagac atccgcatga ttttaagtgt
    27001 aggagaaatc gaggagtaag agactcgaaa aagcgttcag taatgggtaa gaaagccttt
    27061 ctaaagaagc gattgtttat ttgatttaaa aaatagcaag gaggctggga ttccatttta
    27121 tcccagcttc cttgctatca tttttttatt tctattttta aaggttatac aaagattgtc
    27181 ttcattgtct ctaacagctg atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt
    27241 tcaattttgc gttctcgatg gttgaaccaa agcgcttgcc agttagcact ttttgcacct
    27301 agaacatcat tgtcgtaatt atcgccaacg tataaggtct cttctggaag catatgaaat
    27361 tctttctcag ctagctgaaa aatctctttt tctggttttt ggaaacctgt tgcttgagaa
    27421 atgagcatat tgcgggaagg aatccaattg ttcaattgaa gttgcttcag tttttttgtc
    27481 tgatggtcag tcggcccatt tgtgataatt cctaatggga cattcttttc cttcaagaaa
    27541 tcgagggttt ttttgacctc ctcatgcaag cagatattat caagttcttc ctcgtaaatt
    27601 ttttgaaata agaggccatc ttcttccgta atatgagggt agtctaaatc ttttagtgat
    27661 tggctgatcc gatgtgctcg catatattct agtgtccaat ctcctgccat tacttttggg
    27721 aagttttcat cactatgatg gcggaaccgg atatatagtg gatgcatatc tgcatctgaa
    27781 acaagcggaa cgactctttt gaccgcgttt cgaaatggct gctgctgatc atacatcgta
    27841 tcatcaacat caaacacaac tgatttaatc aaaattttac acgcctttcg gttttcattg
    27901 attttttcac aaatccttga ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat
    27961 aaaggttttt cttactatat ttctatttcc ttgacagaat aaggttttta tatttcagtt
    28021 tttttcacta aaaatcgtga aacacgtcaa taagtttgat gaacaaatta atcattatgg
    28081 tagaagtcga ttgatttatt ttaatgcaat ctctgtggaa ttttcgaaag
//
LOCUS       DADVXE010000033        27809 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.033, whole genome shotgun sequence.
ACCESSION   DADVXE010000033 DADVXE010000000
VERSION     DADVXE010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.033"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(274..1218)
                     /locus_tag="KB913_001549"
     CDS             complement(274..1218)
                     /locus_tag="KB913_001549"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBB6819916.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1514..2458)
                     /locus_tag="KB913_001550"
     CDS             complement(1514..2458)
                     /locus_tag="KB913_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6819917.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2679..3893
                     /locus_tag="KB913_001551"
     CDS             2679..3893
                     /locus_tag="KB913_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6819918.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            3915..5930
                     /locus_tag="KB913_001552"
     CDS             3915..5930
                     /locus_tag="KB913_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBB6819919.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6013..7386)
                     /locus_tag="KB913_001553"
     CDS             complement(6013..7386)
                     /locus_tag="KB913_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBB6819920.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7412..7696)
                     /locus_tag="KB913_001554"
     CDS             complement(7412..7696)
                     /locus_tag="KB913_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6819921.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7698..9713)
                     /locus_tag="KB913_001555"
     CDS             complement(7698..9713)
                     /locus_tag="KB913_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6819922.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(9892..10197)
                     /locus_tag="KB913_001556"
     CDS             complement(9892..10197)
                     /locus_tag="KB913_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBB6819923.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10286..11317)
                     /locus_tag="KB913_001557"
     CDS             complement(10286..11317)
                     /locus_tag="KB913_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6819924.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11524..12399
                     /locus_tag="KB913_001558"
     CDS             11524..12399
                     /locus_tag="KB913_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6819925.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12551..13393)
                     /locus_tag="KB913_001559"
     CDS             complement(12551..13393)
                     /locus_tag="KB913_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6819926.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13485..15362)
                     /locus_tag="KB913_001560"
     CDS             complement(13485..15362)
                     /locus_tag="KB913_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6819927.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15359..16780)
                     /locus_tag="KB913_001561"
     CDS             complement(15359..16780)
                     /locus_tag="KB913_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6819928.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16783..20172)
                     /locus_tag="KB913_001562"
     CDS             complement(16783..20172)
                     /locus_tag="KB913_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBB6819929.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20429..21820
                     /locus_tag="KB913_001563"
     CDS             20429..21820
                     /locus_tag="KB913_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6819930.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(21893..22540)
                     /locus_tag="KB913_001564"
     CDS             complement(21893..22540)
                     /locus_tag="KB913_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBB6819931.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22548..23234)
                     /locus_tag="KB913_001565"
     CDS             complement(22548..23234)
                     /locus_tag="KB913_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6819932.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23240..24313)
                     /locus_tag="KB913_001566"
     CDS             complement(23240..24313)
                     /locus_tag="KB913_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6819933.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24535..25209
                     /locus_tag="KB913_001567"
     CDS             24535..25209
                     /locus_tag="KB913_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6819934.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25214..26554
                     /locus_tag="KB913_001568"
     CDS             25214..26554
                     /locus_tag="KB913_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6819935.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26703..27689)
                     /locus_tag="KB913_001569"
     CDS             complement(26703..27689)
                     /locus_tag="KB913_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBB6819936.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8111 a         5250 c         5047 g         9401 t
ORIGIN      
        1 gttaatcaaa tatgaacgaa ttagatatga atcattgtat ttgccgttgc ggaaggattt
       61 tttaattaac cacagataaa cattgataac gattcgctta ttgtaatcaa cagattaaat
      121 ttcatatgtt catatgtacg gatacatttt cggaccgatt aattttaacc attctattta
      181 tttgcttacc tattagatat caataaaaaa ctgcttaaca gctatttcag ctgttaagca
      241 gttttaggat ttttagttca tattcattgt ttcttataat acagtgttca atacttctct
      301 taaagcactt gttgatttgc tgaacattgc tttttcttct tcgttgattg ataattcaac
      361 aacttcacga acaccatttt cgtcaacgat tgatggcaca cctgtaaaga tatctttttc
      421 gtcgtattca ccagttaaat aagcagatac aggcaataca gcttgttcgt tattcaagat
      481 agcttttacg atacgtgcag tactcatacc aataccatag taagttgctt ttttacgatc
      541 aatgatctca taagcagcat tacggacttt atcagcaatc acatctaatt catcttgggc
      601 aatacgatgg tctttttcta caatttcaaa cactggttta ccaccgacag ttgtatgtga
      661 ccatgcagca acttctgaat caccatgttc acctaagata tagccgtgga cgctgcgtgg
      721 gtcaactttt aatttcaatg cgatttcttt acggaaacga gttgtatcca atgttgttcc
      781 agtaccgata acacgtgatg ttggcagacc agattcgttc caagcgatat atgtcaaaat
      841 atctactggg tttgaagcaa caacgataat accgtcgaat cctgatccca tgatttcttt
      901 tacgatttgg cgcatgattg acgcatttgt tttaactaaa tctaaacgag attgaccagg
      961 tttttggttg ataccagctg tgataacaac gatatcagca tctttacatt cttcatagcc
     1021 acctgaccat acagccacat tttcatcgcc ccaagccata ccatctaaaa ggtccaatgc
     1081 ttccccttct gctttttctt gattcacatc gatcaatact aattcattag agattccttg
     1141 gttgatcatt gcataagcga tacttgttcc aacaaaacct gtaccgacga ttactacttt
     1201 acgacttgtt tttttcatga ataaacagct ccttttcata actatttgtt actttcatga
     1261 aaagtatagt cttgtttatt cattttatca acatgttaat tataatagtt gttattataa
     1321 tttttgatgg aaacgaattc ctgaatacgc ataacagata aatgacaaat gtttacacct
     1381 atatcccctg ataatacaac caaaagttta gaactgaaaa taaatccaaa aaaattcgct
     1441 gcaacgatat aataagacag caatcgcacc taaaacaatt ttccttcata tgctttagtg
     1501 aaagattttc ttcttaatgt ttatttctcc attcattggg agtacatgtt gaatacttct
     1561 tgaataattt gaataaagaa gtcgtttgtt tatatccgat acgattagcg atttcttcca
     1621 acgaaaaact cgtttcttga atcagttcca acgcaaagtc gaattttttc tttagaacca
     1681 gttcttgaaa ggaagcatca aaatacattt tcaatttatt actaagatag accggattgt
     1741 agccaaaatg agctgctgtt tcttttaacg tacaagaagt aaaatgctta tcgatataat
     1801 ctaatactct aagcatctca ttttctgcgc atccatctgc tgatgaaaag ctttgttgtt
     1861 ctaataaatg agtcaattcg atcagtaata gtgatgtata gagatttaac gaacggatct
     1921 tatgactgta tgtatcaaaa taaatcaaca gcatattttc aatcaaatgc gtcaaacgac
     1981 ttgtttttcc gccgcgaaaa tgaatgaatt gtgtatgttc ccctttttct tttgatgcat
     2041 ttatcaaaaa agaagaaagt agattatttg tgcttgccaa atgattcaat atctctgtag
     2101 ataaggtttc ttcttttaat aagatgttga ttaaaatatc ctcttgccct gtgtattcga
     2161 ttctttgagt agcttcttta tcaatgatca ccacgtcact ttcttccatc tctatccttt
     2221 ctccattaat aatttgtaaa catgtaccgc tatacatata attgatttca acaaaatcat
     2281 gtgtatgctc gggaacttcc gcatatcgac ggtgtttact gatatgaata tttccctgtt
     2341 gaaatagatc ccctcggtgg atttttggcg gtgtctgaag atggtaagct aagtttaaat
     2401 cattgatatt cattccttgt tcacgctgca gagtttcgat tgattcttcg ttacgcaaaa
     2461 aaaatgtcta attcagctag ttccaattga ctccctcctt tttgtaagcg gtttctttcg
     2521 cttattagtt cacgctgtac tgctattata tgcaaagcta tttttggttt cataaagact
     2581 ttctatggtt gggacatgaa cttcctgtga ttccgctatt gagagaataa ccacttcata
     2641 ctatattttt gataagcgct tacaaaaatg aaaggaacat gcttatgaat aaaaagatga
     2701 tgaaattttc tctgctgtca gtctctctta ttttgacttc tgctggtgca gtcacgtctg
     2761 caattcccag tatgtcagct acttatgcca cgcgttcttt atctgctgtt gaattattaa
     2821 cgactgctcc ctcttttatg gtcactattt ttgttttgat tagtagtttt attgctagga
     2881 aaatcggaca aaaacaaact gtgatcatcg gattagtgat tgcatcgatt tgtggtatcc
     2941 tccccctctt ctcacaaagt tacagtattg tcttagcttc aagagctgga ctaggtattg
     3001 gctttggatt gatcaattct ttggcagtca gcatgattgc tgccttttat cacggagatg
     3061 aacgagcctc tatgattggt tttcaaagtg catttcaagg atttggtgca gctttaatga
     3121 catttgttgc aggacagcta gtacagttcg gttggcaata taccttttta gtctacgcca
     3181 tcagcttacc tattcttgtc ttgtttgttt tgtttgttcc tacacctgaa acaactgaac
     3241 ttcaatcgca tggcacagcc ccaacaagac aagtaatcaa aacgaatcct aaaatgatta
     3301 gttatggtat ttttctcttg ctggtcatcg tggtatataa tgctgtatcg attaaattag
     3361 ccacagtcct gacgacttat tctctaggaa acgaaactaa tgcagcgaat atcttaacaa
     3421 tcatgcaatt ggcaagtatg gctgccggag tttgttttgg ctggcttcag acaaaagcac
     3481 atcgctatat gcttacactt tctttactac tgatgggaat cggctttgta ttgattgcca
     3541 ctgtgataaa cctgtatgtg attgggtttg gtgcgatcct aacaggaatt tctttttcgt
     3601 tattcattcc ttacttattc aaccaagtaa gtatccaagc gcccaagtac gcggagagtt
     3661 tcaatacttc aatcttattg gttggcgcta atttaggtac tttcattgca ccatatggtt
     3721 tgctctttct ctcttttgct tctcttggga gtaaaacact tgctgttttc gtcaatggca
     3781 gtatcttgct gttgattagc gcgcttatta gccttctagt agtacacagg acgaatagaa
     3841 agacagtgat aagagtagat gaagaaataa aagaacaatt gacaacaaaa taaatttgat
     3901 ggaggtcgtg taaaatgaca aatgaaaaac ataaagatag atggctttgg tatcctggag
     3961 actttgagat ccgccatgga ctgctacaaa atttccaacg ggaagaacga ggttttgact
     4021 ggccagcgta ctggtacatg gatgattgcc atcggaacgt caagtttaag agatattact
     4081 ttcttgatca accttccatg tttaaagtga cgatccaagg agttgggtat gtagaaatta
     4141 atggacaaaa acatccatgt ggaaaatggc tgacttgtcc agctggtaaa gcaaaaattc
     4201 gtatctttgt aggacataca tcagggctac cagcgatgtt tatcgaggga gacgaagtaa
     4261 aatcagatat tggctggaca gcaagtaatt ttattgaaga atatccagct ggctggagtc
     4321 cgctttatgt cgatatcgca aaagatccaa atcaaatcta ttatcaaaaa gaatgcgtcc
     4381 atccagtcac tgaaacggag attggcggag gaatcttatt cgattttggg cgagcagtga
     4441 atggctgtgt agaactaata tctctggatg accatatcga atctatcact ctatgttatg
     4501 gagagtccga tgtagaagct atggatatcg attattgcta ctataagcaa ataggaatga
     4561 caagaaaaat gaaagctcgt aaacgcgctt ttcgctattt gtttatacca gaggtttcta
     4621 ctggaatggt tcaacttcaa gtttttcatg aatttttatc tctttcgaaa caagctgctt
     4681 tttcaagcga ttcttcttta ctgaatcaga tctggtcagt atcagaagaa gccttcaagt
     4741 tatgtagtga tttgtttttt atcgacggta tcaaacgaga tcgctggatt tggtctggag
     4801 atgcgtatca atcattcatg atcaatcaat atcttttttt tgacgaggaa atcaataaac
     4861 gaacgatatt agcattaaga ggacaaaatg aaatcaagca gcatatgaat actatcgttg
     4921 actattcgat cttgtggttg attggtatcg aaaaccacta tatgatgacg aaagactatg
     4981 aatttttacg catcgtctac cctaagatgc aatcattaat gagatacttg atggagcaaa
     5041 cgaatgaatt agggtttatt tatgggagag caaaagattg gatatttatt gattggtctg
     5101 aaatggataa agaaggaacg cttgctgcag aacaagtctt attactgaaa gcctatcatt
     5161 ccatgatcac ttgcggagat atcttagctg aaacatatgg agagaacgaa aattatcata
     5221 ctcatctcta tcaagaaaaa tatcaactat tgaaacaaaa cctatttgac tacttttggg
     5281 atgaagaact tggcgctttt atcgattgct atgaatctgg gagaagaaat gtgacgcgtc
     5341 atgcgaatat tttcgctgtt ttattcgatt ttgctaacaa agaccaacag caatcgatct
     5401 taaagaatgt cttattgaat gacactatca cacagattac tactccatat ttcaaattct
     5461 atgaacaaga tgctttatgc aaactcggac agacgaatat cgtctaccaa acgattcttg
     5521 attattgggg agggatgtta tctcatgatg cggtaacttt ctgggaagaa tacgacccta
     5581 ctcaaacagg aaatgaaaag tacagtatgt atggagatcc ttatggaaaa agcttatgcc
     5641 atgcatgggg agcaagccca atctatcttt taggacgcta ttttatcggt ttgtatccaa
     5701 caaagccagg ttatgaagaa tttatgatac aacctaatct agattcattt gaaacactga
     5761 attgtacgct acctatcaaa gatggaaaga tttcgcttga aaaaacaaaa gataagatcg
     5821 tgattacttc tgatagaaca ggcggaacag tgaaaatgaa tggtaaaagt tatcctcttc
     5881 tagcaaaaca gccacttgtc ttaacaagct attcaaaaat aaatgcataa aacaaaaaac
     5941 tgcttgcgac atatcagaag actttaaatc ttcttctgat attgtccaag caatttttat
     6001 tttgaagttt gcttaattct gttctttaga aacaatgttt gttctttttc cggcaaaaag
     6061 aaagctagat aatacgacaa gtaaaaagaa agcgatgatt ccaactgtca aggctatttg
     6121 accgtattct cctagtttcc caagtacaag tcctggtact agataatcag tatcggcaaa
     6181 tgtagaagaa gcgattttaa gatctcctaa tactggaagg ataaataatg gcagccaact
     6241 aatcaataag ctattgaaag cagaacctaa taccgcccct cttctaccgc cagtcgagtt
     6301 gccgaagaca ccagaagcag ctccgcagaa gaaatgtcct actaccccag gaatgataac
     6361 tgtagtttgc aagcctatca tagcaaacat ggatagtgtt cctacaaaga agctaacaaa
     6421 aaagccaatt aatacagcat taggtgcata tggaaaaacg ataggaacat ctaatgctgg
     6481 tttagaatcg ggtacgagtt ttttagcaat cccttggaat gctggaacga tttctgccaa
     6541 caccattcga accccttgaa ggacgataac aaacccagct gtgaatgttc cagcttggat
     6601 cagtgcaaag attacagcgt tgtctccatt gcttagttct ctttcaacaa atccaggacc
     6661 agctaacaaa gcaagtgcga catatacgat cgacatcaag agcatgatcg atacagtaga
     6721 atctcgcaaa aagctgaaac ttttaggaat ctttatgtcc tctgtagaac ggtctttgtt
     6781 tccaaaaaac tttccgatcc atccactaga agcataaccg atatttccgg tatgccctaa
     6841 cgcaacttga ttgtttccag tgatgttctt cataaacggt tgacaaagag caggcgtaat
     6901 agttaatagt gttccttcga agaccccgcc taataagatc atccacaaat ttgcagtaaa
     6961 ccccgcgctt actaaaatga ctgctgttag acaagaaaca taaagcattg cttgacctgt
     7021 aagaaaaatg aatttatatc ttgtgaatct agcaagtaaa atattcacga tcatccctac
     7081 tagcatgatc aaagcagtag gtgtaccgta ttgttgcaaa gcaatcgcca ctactgcttc
     7141 attgctagga actactcctt gagtatgcag agctgtttgg aacatcgaag caaaaggggt
     7201 tagtgaatta ctgattaaac cagcaccgcc gatcagtact aggaatccga caaatgtttt
     7261 gatagttcct tggatcactt ctgaaaattt cttcttctga agaacgagac caagcagtgc
     7321 aatcaaagaa acgaggatgg agggctgact gacgattgac acaaacaaat tcaacaattt
     7381 atccattgat agttcctccc ttgaatcatt tttattcttt tgacaagatc ttcgttactt
     7441 tttcttttac ttcttcgctg tcaatgatcg attgcaaagg tacgagcttt tcatcaggta
     7501 tagaagttag cgtatctttc aaagaatgct caatgaagaa ataatcagcc atatcgctag
     7561 atacacttcc aacatccgta tgacttactt caaactcgtc cacatctgct ccaagatctg
     7621 caagtgcttg tttgatgttc atctctacca taaaacttgt tcctaatcca ctttgacata
     7681 ctgcaaaaat tttcatatca ttcgtctcct tttcttatga tcgctaatat ttcttctttt
     7741 gttgatgcgt gtaataaatc ttgaagattt tgtttattag aaagtagctt tgttaaattt
     7801 gccaaagccc gaagatgtgc ctcattatcg atagcagcta aacagatgaa caaactaatg
     7861 ggatgggctg gattatcaag cagatccaca ggttgttgaa gtttcagcaa agacatccct
     7921 acttcgttta cgccatcttc tggacgagca tgaggtaatg cgatgtgatc gccaatatgg
     7981 ataaacgcac catactgctc cacgcgctcg atcatagctt tgatataact ttcttctatt
     8041 ttattttctg ataatagcgg ctgtgcggca aatgtgattg cttcttgcca gttttttggt
     8101 tgatccgata attggatcat ttcttctgtt aataattcag atagcatagg acgttgatcc
     8161 tccttctttt ctaaaagttt gttcatttta cgatttaata cttgatagag cttttcttcg
     8221 tctacgcctt cttttaattc gatataaggc agtagcgccg acaacaattc ttgggcagaa
     8281 ggcattgaaa atcctggtat cagccaatct ctttgtactt gattgatcag ctgatttttt
     8341 tccaagtcag tcatgattgg atgcagaaca tagagagact ttttcttatc agtaagtgtg
     8401 agaggtacag tagaaaaaat aatatcgtaa gaagtttcgt caacctcgtg taagcggtca
     8461 gctgaattag tctctgtaaa aaagatcatc gggaataatt gctgaagttc actttttaag
     8521 atcaatgaag agctaatgcc acttggacag acgatcacgg ctcttatttt tctatttctt
     8581 tcttctgcgt ccgcttttct gatctctccg ccaaatagta tagtgaaaaa accaatctct
     8641 tcttcaggga tgctcttccc tattcgtctt tctaacggaa gtaatgcttt tcttgtcatt
     8701 tcgtagatgg aagcatattg atgcttaatt tgatcgatca tcacattagg taaataaaaa
     8761 gaataggaaa tacgaaaata ggcagggacc aagtgataaa agacattcat caataattca
     8821 cgaaacgaag caaattctac ggccatcagg aattccatgc gatggatgac ttctgaagaa
     8881 cattccagca aaaaatcaag tgcaggctcc tggacatctc cttcaacgat cgatgctaag
     8941 caaagagaga aaaatataat ctccgaattt tgatgttcgg aatagccaag gccagtcaat
     9001 acttgtcgac taatgtcagt gactgcaaga gaagccaaca gttcagcatc ttttaccagt
     9061 tccatggatg tttttccaat tcgaatggtt gtcaaactca aataataagc taattcatcc
     9121 attcgatttg gtgcgaatcg aagatctgat agtgaaatcg ttttatctag caaatctcta
     9181 actttggcgt aataatcaat ggaaagggtt gcggttaaat acgtgagccc aaatcttcca
     9241 gcaagtgact gcatcaaacg agcagtgcga ttttttgctt ctcttcttaa tattgcttct
     9301 gaccctagca gcctaaaacc agttttccta gtatacgaca gctgacaatc ttccacttct
     9361 aattcatttc ttatcttttt gatatctgac aggactgtcc ctttagaaac ctgaagaaaa
     9421 tcttgaaaat gaaaaacaga aacagacgtt gcagtcgaat aaaccatcaa ataaagaaga
     9481 tctcttcgct cttgttcggt atacacagct tcaaatcgag taatatccaa aaatttttct
     9541 gcccagtcga ttgctcggaa tttctttata cggatacggg tatcatccac atattcggca
     9601 aaaggagtta attgtttgat cgcctcgctt gtatttactt cgatgatctc tgctgctttt
     9661 tctagactga tttctcttgg tgttttcagg agataactaa ttttgtagtt cacagcgctg
     9721 ttcacctcct acttatattc tagtatggta gcgcttttaa atcgaggggt gtttggtaca
     9781 acttacagtt ggattttttt tacgactgta ccgaacgatt tctatcgaat ggatacagaa
     9841 aaaaagcagg tgaccaaatg tctcctgctt ttatgaattg atttcgtccg atcaatgatg
     9901 atcatgttta ttttttgagg tcagttcttc aaatttttct ttgacatctt caaccgcttt
     9961 ttcgatatct ttttcaaagt gattgggctc attaggcttt gtttcctctt ctacagaatt
    10021 tgaaccagat aaagctgttt ctttattttc tgtttcacca gagtttgtgc cagctaatga
    10081 ttcttctttg tcttctgttt caccagaatt agttcctgct aaagccactt cttcttctgt
    10141 tttaggggcc attgaacctc ttaatcgttt gtgtttttca ccgtcataat ttgtcatgtt
    10201 ggttcctcct agtagttcta tactttttca tcgtacaata agacagttta tgcgtcaaaa
    10261 aacaaacccg attcttacaa atatgtcata tttttccttc tgattcttga atgcttttga
    10321 ttccttcttc caaaattttc atttgtaaga ttgtttcttc atctttgatg actttttctg
    10381 cgccattaac taatgtctcg taaatccctt cgtagacacg gctgtaatca ccaacctcgg
    10441 aaattacttt ttcttcatga taactccctt gttcatctat ataggtcaat acaccataat
    10501 gttcgggcaa atcgatacca aagtcttcat gatcaggcat gtaaaacatt ttcagatgtt
    10561 cttcttgtcg atcttttgtt tgtttcacga acatcccttt ttttccgtaa acgacgaaac
    10621 ttggacgttc tttgatgcgg aaataactgg attttatcga aattttcata tttccataga
    10681 aaaaatccag atcgaagtaa tcattcattc gtcctttccc taaaagttga cgtacatcat
    10741 agctgatatc atctggttcg ccgaaataag aaagaacttg atctactgta tgacaagcat
    10801 gtccatataa atagctgttc gcagtagaaa attcatgcgt attttctggt acttccggtc
    10861 tgaaataatc ataatgcatt tctacttcta aaatatcccc taattttccg ctttcgatta
    10921 ctttttggac tgtcaagaag tcagaatcga accgtctgtt ttggtaacat tggataaata
    10981 gacctttttc ttttgctaat gcaaataact cttctgcttc ctttgacgtt tctgcaaaag
    11041 gtttctctac tagtacattc ttaccatgtt cgagtgccat ttttccatat tcataatgaa
    11101 attgactagg tgtagtgatg acaactaatt ggatctcagg atcatcccaa agatcagaca
    11161 gctgatcagt atattcgatg tcttcgaatg ttttccacac tggttcagat ggggaaaaaa
    11221 tttttttgat attgattttg ttcgtaagtt ttcttgaaaa aggcaaatga tagcgatttg
    11281 tactctttcc attgccaaga taagcgattg taagcatgag tggtgcctcc ttttattgat
    11341 gttttcagta tatcctagaa aagcgcagaa agtatttata atagctattc tggtaaaaaa
    11401 gttcagaaaa acacttgtta tcattcggtt tggtgaaatt aatgttcaaa gtaaggataa
    11461 aaatcaaaaa gatagtagcg gaaccaagtg tttatcagta agatagaatt tggaggtcag
    11521 atcatgctta ttgaagaaaa actaacaaaa caagagttgt ttaccacgac agagaaacgg
    11581 attgtcgatt acatccgtag gaatatcgaa gctgcagtct acatgacgat tgaagaatta
    11641 gcaaaagcta cgtatacttc ccattcagct atcattcgtt tatgcaaaaa aatgggattc
    11701 agcggattta aagaattccg tttcgagctg gggcgggaag ttcatcaatt gattgctcag
    11761 ttcaatcaaa cgattgatcc taattttcct ttttcaagtg aagatagcac tcagcaaatt
    11821 gcaaagaaaa tggcggattt atcgatccag tcaataaaaa aagcacaatt gcagattgaa
    11881 catgaagatt tagatcaaat cggtaaagta ttgaacaagg cacagcgaat ctttcttttt
    11941 gcaaaaggtg attctcaaat cacggcaagg aaattccaga ataaaatggt caagttgaat
    12001 aagtttttga tcatggctga agaatacagt gattcttctt ggaatgcagc caatttgact
    12061 agcgaggatt gcgccatttt tattagctac agcggtcgca tccatcatta tgaacgaata
    12121 atgacctatt tgaagcatgt agaggcccct accttgctga ttaccggaaa tcagcattca
    12181 gaaatggcca aacaggctga tatgtgtctt gttatatcgc aggaggaata tgattttgct
    12241 aaagtagcga ctttctcctc tcaaattgcc ttcgattacg tattaaatac gttattctca
    12301 gtgatatatt ctcaaaattt tgaagagaat atccgcaact tgaaaaacaa acaagaattg
    12361 atgcaaaaag gccttcttaa agaatatcgg aaaacttaag aaaagatcct catttagtaa
    12421 taagaaagat agtgtttgat aggctctctt tgatatcatc ataaaaacag gctgaagttt
    12481 tctttttcaa acctcagcct gtttgtttac ggaacgattc gaatagatat attatagaaa
    12541 tgaggaatag ctaacttctg tttcttattt tgaacgattg acgaaaaaga tatataagaa
    12601 ggaggaaaat cagtatacat gcagctaaca atccatacag gaaaaatcgt ttgttctcgg
    12661 atactttctg tacttctttt tgaacttctt ttgcatgata aggaacccgg tgccctctga
    12721 caagtaagcg atgactgttg accatataag gtgtacaagt taggagtgtc acgaaatcct
    12781 gccctttttc gattctcaga tcttttgtat cagtcggttc taccgtcttg atctgatcga
    12841 cttgataagc gagtgtccgt ccattgattt cgatatagaa agaatcacct aaagtcagtt
    12901 tcggtaagtc tgtgaacaac tttgcttgag gcagtcctcg atggctggaa ataacggcat
    12961 gtgtattttc tccccccgta ggataagacg ttccttccaa taatgaggca cctttttcta
    13021 gcagcacagt attcgtttca tcaaaaattg gcaaatggac attgatctca gggatcgtca
    13081 aaataccgat cgtatgtttc tcaaaatagg ttctatcctt tttcgcaggt tcttttttct
    13141 tagtaaaggg atctgcacct ggatttccac cttcttttgc taattgctgg tttttctttg
    13201 tcatgttttc ttggatttta gccatgactt cttcattttc tttgaccgct tgttgctgat
    13261 aatgagagat gatctgctga tccagataat tattcagcgc gtcgctaaca aatggataag
    13321 ctagtatccc tattcctgag agaagcaaga aaagcatcag cagatctaga agtttccttt
    13381 tctttggttt catttgtgtt ctccttgtga tgactgtttg ataataaaag aaaaaggagc
    13441 atttgcgtaa tccgctgctc ctttttccaa ttcttgcaaa aagactaaat ctgactgtgc
    13501 ttgcgtctag caaagtacag tccagcaatc agtagaagga ctactcctgc accgatatac
    13561 acatagattc ccttaccgcc tgttgaagga agtgtacctt tgtgtttatt tggtattttt
    13621 tcaggagaaa tcaactgtcc tgctgttaca taagattgtt catcgatagt aaatgctaca
    13681 cggtttgtta atggaacata tttttctggc gctttcgttt cttccagata gtacgtgcca
    13741 tattttagac ctgtcacatc gattaaaccg ttacttgtgg ttgtaaaaac cgttgctgat
    13801 tctttcgccg atacccagct gacggctttt gtggatgggt cgatcgataa atatttcgct
    13861 gtgtcactat cttgatcacg aacgacgaat tctgctccag caagtgtttg gtctgatgta
    13921 acgtcaccat ctactttaac aaatcgtttg cccccagtaa cgacatcgac tgacggtggt
    13981 gtttgatcat ttgtatgccc gttatcgaca tttgcttggt tagaaaatcc tttggttgga
    14041 tctgcttttt cgttcaaatg catatagtaa acgaatttca atgtaccgcc aggagttaat
    14101 gaaggaatat aattcggatc aactgaaacc gtgaatccgt ctgtttgctc agtgacagaa
    14161 taatttactg ggtcgatttc tttatttcca tcatataagg cataagcata cgttcctgaa
    14221 gaatcattat caaatgttaa agcagcgtca tgagtatcga taagtttgaa tgttgtgtac
    14281 ttgttttgcg ttccttcttt atcagcgata cctaatggga tattgacaga aatctcatat
    14341 tgaatttttt caccgattgc gacatctttt ccattcaatt gaggtgttgt tttatcaact
    14401 ttagacgtat catttttgat ggtcttttct actggtgttt ggctatttgc caggatctca
    14461 aaaggcgtga ttgtttgctt ttcaatcatt tccgcattat caggagcttt tacttcttct
    14521 aaattatatt ttccaacttc taaatgatta acgatcaact ggcctttttc aatagatgcc
    14581 tcggcaaagt cattgttgcc gatgtcataa gaatgaccag taatgaaatg tttggctttg
    14641 gtttgatcag ttgtccaagt gtacaatcca tctgtgacac tttggatgta ttttttgacg
    14701 cttggtgttc cttcttcttt agaaataata aattctgctc catttagtgc ttcgttttcg
    14761 gcagtaccga tttttgtaac tttcaacgtt ccatcattac cgactgtatt tttagggtag
    14821 agatggatag tatctagttc ttctgtcccg tatttataag agccatctgc ttgtttgatc
    14881 atctcatata cagggaaagc taaaaccatg tttgcggcag ctgacactcc gtcttttggt
    14941 tcttctttga tcgtgtagac tgcatctttc ccattttgtt ttttaggtaa agataaagtg
    15001 acatttccat cagcatctgt cgttcctgaa gcaactggtg taccaggagt caaagactgg
    15061 actgcttgtt ttgctgcatc cacggacgct cctttatctc gttgcgcata aaattcttga
    15121 gtgacgttat aaactgaaaa tgaaatatcg gctaatcctt ggtattgatc gaattcgctc
    15181 atttctttcc cgctgttttg gattaaagga tcgggtaaat cagtcatttt ctttttatga
    15241 aggatgactt gagctgctgt ctcctctgca aacacttttt ttgcgccgaa gctgtttgtg
    15301 agtaatggta aaataaggaa aaggactcct aacataacgt ttattttttt atgatttttc
    15361 attttttcac tcctgttctt tttttgataa acaaccagat tgcaaagctt gcgaatacca
    15421 taccaacaac gcctaaaagt gtatttttcg tttcgtttgt ttttggaaga aatggacggc
    15481 tattttcttt tttattgact actttcaata tactgtccgc ctctttatcc tcagaaagaa
    15541 aagttgaaat ggtaaacgga atttctgttt cacttaaaat ataaccagaa ggtgcttcga
    15601 tctcttttaa tcgataactt cctgttttca acccggaaat tgaaaaagcg ccatttttat
    15661 cggaaatcag gtgaagcgca tctgattcgt tctttgtcca cttgtatccg ttggctgttt
    15721 gctggaggta atttcctgct ttgtttttaa taaggaatac tgcgccagct aatcgtttat
    15781 ctggtttatt tgtctcgatt ttgacaaatt gcttactccc tgtatataca gagactttct
    15841 ttgtactgac accaaaacca aaatccagtg ttccgttgtt gttgatttcc ttgttcgcct
    15901 gtgctgtact gcttagctgc atctgataag aaatggtcag tttttttcca gcatattttt
    15961 ccaacgaagg gatcgaaaat aaaacatcaa atccgtgagg tttcttgtgt atgacaaagc
    16021 cttctgtcag cttttctcca ttcgatgaaa tcgttaaact attaggtaaa aacgttaatg
    16081 cttcatccgc actatctgac aattcgaact tttgatagtc aaggatattt acaggaattg
    16141 tcgtatgcaa ggaataagtg attttttcac caatcgtaaa atcatttcta ggctcttcta
    16201 ataccttctc aaaaggtgga tcagggtagt cgttttcttc atttttagga tacaaatgga
    16261 tagttgaaag tttttgattg ttttgtccat gtacaggaag aacaactacc atattctctg
    16321 ccttttcttt gacgacttct ggtactttgg attcaatgaa aagatacgct ttatctcttt
    16381 tttcttgatc tttagcggcc agagaaaaag aagcgatacc atcttcgttg ttaagagttg
    16441 tagttgttgc ttctgcggta aacataccgg aagacgcacc gttttttgcg atctctgctt
    16501 gtgcttcttc taccgttttg cccttttccc gtagatggta aaaagaatct gtgacatcat
    16561 aaacttggaa tgtgacacca tttaatcctc gatacgtttg taataaagct ttttcttgtc
    16621 cgtcatttgg atgatttttc ggcagttgcc cgtttgggaa aagcaatttg tgtaaagtaa
    16681 tctgaaccat ttctgtttct gtttctgttg ctacctgagt aaaagctggt ttaaatagta
    16741 acaagaagag acacatacta agccaaccaa gttttttcat atttagctgc cccctctttc
    16801 ttttttcaaa aaaagatacc aaatagaaaa cgcacaacca atcatcccta ctagatagat
    16861 tcctaaacgg ccaattcctc ccgtttcagg taatggtact tttgcctgat tcgtgatgtc
    16921 taaagaaatc tggttgtttt tggctcctgg tgacagaaca gattcatgat cttgtccatc
    16981 cacttgaatt gacccatctt cgtgtataac tatagtaact ggctctttta gaccttggta
    17041 tccttctggt gtaaaagttt cggtcagcgt ataagttcca ggttttaaat tttcgaatag
    17101 aaaggtatct gtttcttgtc catcttttgg cgattctaag tccatttctg gtccctgcag
    17161 tctgaatttt gctcctttta atgtctgtcc gttgtcttct tttttgtgta ccgttagatc
    17221 aaacgctttt agtcgatttt gatgagtgag cgtccataca ttatttgtca tctcggtatt
    17281 ttttcccgtg taaatgattt ttccatattt atcgatttgg aattcataat ttcccggcga
    17341 agtatcatat ccggcaggac cagctgtttc aacgactcga tatttaccag gtgtgagtga
    17401 atcaaaactg gcaagacctt tttcattcgt tgtttggctg tcaattggct gataagtacc
    17461 atttgcttct tttttctgta gggaaaatgc tgctccttta agatttatct ctttgtccgt
    17521 cccttgcatc gcatacttac gtactgctac aggaacttca acaaaaggat tttcaatagt
    17581 caactggatc gtatcatcgg aagtagtgac tgtttttcca tcaatggtta ccgtaccatc
    17641 agaagcgatc ttgatttccc aagtagtctt tttgcttaat ccatgccctt ctggagcttt
    17701 tgtttctgtc agcgtatagg tcatttcttt ttgcaatttg acattttctg gaagagaata
    17761 ggttccgtcg ccatgatctg ttagtaaagt atcaatagaa tctcctgtta atttgaaaac
    17821 agcgccaata agatcctttt cacctgtaga ggaatttttc gttattttca agtttaacgg
    17881 tgtgaattgt ttagtatttt tccatgtcat tgcatctatt tgttgagaat cgtatcctgg
    17941 tacaggtaat tctttgattg tttggtaact gaatgcttga ccttgattat tgtattgagg
    18001 tagtgataat atctcttgat aactttctcc gctatttgca gataatttgt caatgtctgc
    18061 acgttcccac gtatttgttg tatctttagc tggtttaatg attcgaatat atccgttttt
    18121 ccaagctgca gcatttgtcg tatgttcccg ttgaatctca aaagtaactt gatctggacg
    18181 atcagctaga ttgttgtcaa attcttccca taactttttg atgtgaagac tgactccggg
    18241 agctttagca gatggtatac cgaattcagc taattcattg gtatcaatgt ttggctggaa
    18301 agttgtcctg ccgttcattt gataccagaa atttggatgg aagtcctcat tttctgtttg
    18361 gattctcact tggtaatgga tttggatttc ttggtctttt cctaaataga tctgattgct
    18421 cttgatggta tttccttcta tggaaataga tggagtgacc gttgtaggac ttgtccccac
    18481 actcttgact gaaagtgtac caggctgata aatgaatggt tctgcgattg gatcatttat
    18541 ttgtccattg cttacagttg ctgagatctg tacagctttt ttggctaggt attcagagat
    18601 atctgttgca tgatcagctg attcatagta aagatcgcct ttttcatctg atgaaaccat
    18661 ttgtcgcata cgagactcta cttctgcttt tgagagacca gctgccggat cgctttgaag
    18721 ttggatgcca agaccatgta tttcgattcc tcgttctttg agtgccatcg cttctccgat
    18781 ggttgcgata aacgtactgt cgattcttct ggatagattg ttttggtcag gtgcatcata
    18841 gattcttgag attagagaag tatttcccgg ccgatcttgc gtattagaaa actgagttcc
    18901 gtaataattg ctgcttgatt gtgcgtgtac ccgctgtact ttataggaaa atgttggtac
    18961 accatccgtc agcaaaacga tcactttttt atgtccattt ggaacggata gcatgcttcc
    19021 tgcatctctt agtgcttttt gtgtaaaagt accaccattt gtccgtgaag gtgtaatgga
    19081 ttttacttga tttttcactg aatcaaatga acccatctgt actgcaccgt tactgtagct
    19141 atatccttcg cttgagtagc cgacatatcc catattgatt ttgtctgtga taccgctatc
    19201 tgctaaagta tcgacaaaac gatcgacacc aatctttact tcaccgatcc gattattgtc
    19261 gttcatactt cctgaccagt ctacgaccaa tacgagatca agaggcgtga tatctttttg
    19321 tacatttcca cgagcattca aataaacatc aaacaatccg ggtgtacttg tttcctttgc
    19381 atactttcgt atcgcatagt ctgcttgatt accggttcct ccatattcga tatacgaatg
    19441 ggtccgatca ttaggatctc cattccaaga atttatacca tcccattgat ttgttccgtt
    19501 tttattgcct tgatgatcaa gaacatttgt atttcctgta ggttgccaac tggctttagg
    19561 ataagtgccc tgatcatctg ttgtatattc tgtaggaatc gtttgattag atggcacact
    19621 cacagctggc aaggataatg taggcaatgt aaatgggctg acagaatttt cgttttcttt
    19681 tgatgattct tcttctattt cgtctggctt tggtactgac acatctgtat ctttcttatt
    19741 ttctgtctca tcaataatgt catattcttt attatcgacg atcagcttgt ttgcctggct
    19801 gtggtaaagt gctggatcga ttggaaaact cagatcgata gtttgtttag tgtttgatga
    19861 gatttccaac gtaattttcc cgctatttac ctgataagca tagccatctc cttcttttct
    19921 ttccacatca cttaagtaat tttcgactag accaatttct ttttctatct tttcagcact
    19981 ggtgttattc gcatttagct tgatgttcag tgcttttttt ccagactgat ccgaaatgac
    20041 ttcagctgaa attgtttcta aaactgttgg atcatctgta gtgtctgcta ttgcagataa
    20101 tggcacaaag tttgataaac tcaatattat cagcatgaaa ataactttca gtttcttccc
    20161 tgtggtcgtc atttttcccc tcctttttct ttttttctgt tttgacgtga atagtgaaaa
    20221 ttattaaaat aaacaggcgt tacataattt tatttatttt aatatgataa ttattatacg
    20281 aagggcgcta aagggaatca caccaatttt cataccaatt ggtttcattt atgaagttga
    20341 ttccttcgat taatgagcgt ttcattgaaa gaaaagggtt gagggagaaa aacatatgat
    20401 caggttgttg gaaggaaact atagaaagat ggaaaaaatc attcgaattc tgtccatttc
    20461 tgacaagtgg atgactaaaa aagaacttgc caaacgaatt ggtagttcag aatctacatt
    20521 tgtaaggtat atcgaagaga tcaaaatccg ctggggaacg gatgtaacga ttcaatcttc
    20581 acaaaaattg gggtatcgtc ttgaacattt gaatgtacca gcttatttaa atgttctgat
    20641 ggaaatgtcg caaagttcta caaacagtcg tttattaaat gagattattg tcaatccggg
    20701 taaaacgatt gagtattatt gtgaaaaaat ttccatcagc cggtcttctt ttacacgtaa
    20761 gttgaaacaa tgcaatcaaa ttttagaaag ctatttatta aaagtgatcg ttgaccaagg
    20821 ttttcagtta actagcctta aaagtgagct ccagttgcgt atctttgtta cctttttctt
    20881 tttaagttac tacggaagac gcacgttgcc atttccaatc gaaaaaaaga agatcaaaga
    20941 aattatggtc aagaataatt gtcagatgaa tttgtttcag gaagaaagcc catatgagca
    21001 atctttcttt attatgtatt ttgttgtgca tctcatgaga gaatcccaag gaactccatt
    21061 tgaatggaaa gctggagact cttatgtaca gttgataaat atcgataaaa aagacttctt
    21121 aatcttgaaa aatctcttag gaaaattgaa gtacagcagc tatataaaag tagtgaacta
    21181 ttttgtcaat acgatttttt cagaattttc ggagaaagaa aaaaatgaaa tcagtgagca
    21241 gatacgaaaa aatatgtcct actgttcgtt ttcatccgct gattgcaaag aaaaaaacga
    21301 agaatatgtt gttcaattat taacgcaaat ttattttttc tcccgtattt tcccatacga
    21361 tacgactcat ttgacgatcc gtgcaactta ctttgcacag cagatgcaac accgccagat
    21421 acgtctatat gctggatttc gtgcagaact tcaattttat tccactctac tgaatcagaa
    21481 tctgatttat tatttatcta gctatatctt ttggatgctt atcggtaatc ctgaaattca
    21541 ccattatact tctgataaaa aaatactgat tatcagcgac ttaagtcttc gacatagtca
    21601 atatattgaa gaatatatca gtgatattct tgctgtgcat aaaattcact ctgagacaac
    21661 tgctattact gaagatcagc tgtcgaaata caatcttctc gagtatgatc tgatcgttac
    21721 gaatcaaccc attttgaatg cccatgttcc tcatatattg attgatgata gtgtgtcatt
    21781 cgcaaatgaa gaagaactca tccgcttatt cgagttatga ataatcaaaa aacagctatg
    21841 tataaaccac cctgataaaa atttcaggac aaatacacat agctgtttct ttttattgta
    21901 ttccttcagc aatccaacga gatttatagc gaaagtcttt taacaactct tcttttgtcc
    21961 aattatttgc aatgagatcc gtcaaagtgt tcattacgag ggtcatggaa aagtatagga
    22021 aactaactgc ttcttccgac gattgaatgg agaaatgatt gattcttaat aattccagcc
    22081 atttttcgtt cattggagaa tcagccgata gttctctacg tttggttgtc tgctgatcat
    22141 ttcgctgggt taacaagtat aacctttgcc aatagatact ttcgtgatct aagtcgcagc
    22201 accactctaa atatttttcg atccccaaaa agaaatgttg tttgttttcg ctaatgaatt
    22261 ttaagatatc ttgatggact atgtgagaac tgcttttgat cgtatacaaa taagcatctt
    22321 ccaaatcttg aaaatattta taaaaagcac cgcgcgacat ccccatcttg tcaacgattt
    22381 ctgagacttt gacttggctg atgtgctgtg agcaaaatat ctccagtaat aggtcatcga
    22441 ttctctgttt ctttgcgttc gataaattga aaaaagtttc ttttggcatc cacatctctc
    22501 ctttatctct gattatacgt ggatagccct tcattgtcat gaaggattca ttccttcttt
    22561 ttctcttctt ctgtcaagta cccatcttcc attcgataaa cgcgatcact ccattgaatc
    22621 atacggacat catgagtaac cataatagtc gctttttgtt tctcatgagc ttctttaact
    22681 agtaatttga cgacttcata tgcatgatct gtatccaaac tagctgttgg ttcgtctgct
    22741 aagatcaagc ttggctcatt atataaagcg cgagcaattg ccactctctg tctttctcca
    22801 ccagaaaggt ctttaggata actattttta agtgactgga tatctaaaga ttgcagcaag
    22861 gaatcgattt ttgttgaatc ttcttttttt gaagtaactt ggtcaactag ttcaaattgt
    22921 tcctttaccg ttaaaaaagg aatcaaatta gagctttgga gaataaatcc tatttcttta
    22981 aagcgtaaat ctgctcgttt tttttctgga agctcagtta gtgagtgacc gttgatcact
    23041 atttctccgg aagtcggtgt ttgcaatcct cctgaaatgg taaggaaagt acttttacct
    23101 gaaccagaag gaccaatgat gctgacgaat tctccttcct ttacataaaa atcaattgct
    23161 ttcaaagctg agacctttgt atgaccagaa ccaaatgttt tggtaacttt tttcatcgtt
    23221 aatatttttt tcatttttat taacctccta ttgctgtaat tgggtctact ttggttatcg
    23281 tacgtatcga aaacaatccg cctagcattg cgacaatgat caaaatccca ctatatagca
    23341 accattgtga ccaaaaaaca gcaaaaggca tcgcgcttgg taaaatcaga ctagtcaaat
    23401 aagcaaacaa aagagcaagc agaacgccta ccaccccaac aataaaggac tgtgctacta
    23461 aagatttagc gatgaagaaa tttttgatcc cttgtgcttt cattactcca aaaatagcag
    23521 tcttctgaag tgtcatcacg tacatgaaaa taccgaccac ggcagcaacc actaagaaca
    23581 aaaagtatat catcgcattt aaggtcatat tttgggcaga atagccagga atactttcaa
    23641 tgaatgtccc aatagttaat aactgtagac ccttcgatgc tttttctttc gaaattttag
    23701 ctgaatcctt tattacgatc ccattgatcg gctgttcttc ttcagaagca aacggctgtt
    23761 gtccatactt caaagcagtc cacgtatcta gggacgcata gatgacggga gaaactgtgt
    23821 aataagtttc aggaaagata ccgacaatcg tcaaaggatc gtcgtaactg ccaattttga
    23881 tcgtatctcc aattttatag cctgaatcag ccagattttg agagatgatg atttcattct
    23941 ttgttttaaa ttcatgccct ttcgtgagtt ttggtaataa aaatgcttct ttcgttgtgc
    24001 cgaaaactgt aacattttct ttgttttttc ctttgattgc tccgctgtac aatccgattg
    24061 gtgctttctc tcctccttca atgtatttca gatctcctct tgttaattgt gaagctgcaa
    24121 atacttgatt tgcatcctcc gacaaaacaa tctcttgtgc gtcccaatca tcgattgctt
    24181 ttttaaactc ttctgaaagt ccattcgcta gtcctgacaa catgaatacg acatacgcaa
    24241 tcaagaacat aataccgacg atcaagccat atcgtaattt agaatagcga atttctttga
    24301 tagctagaaa catttgtttt tcctccctat gatagattga tagtgacaaa atgtcacttg
    24361 ttgaatagtg taactctaaa gtgacaattt gtcacttgtg ttgttttttt cttatcaata
    24421 aattgtctaa gacatctttc gataaaacct taacatgagt cataaaaaat ttatttaagc
    24481 cttatttatg ctttccatga taaactaaag tgaccaaatc aatgaggtgg gaaaatgatt
    24541 aaactattag tagtagaaga cgataaagta ttatccaata atataaaaga aatactcgct
    24601 gcaatcggcg agataacaca agtttatgat ggtagtgaag gactgttcga gttggaaagt
    24661 ggagtttatg atcttgcaat cttggatttg atgatgccgg aaatgaatgg atatgaagtg
    24721 ttagcaaaaa tacggaaaga aaaaatacag actccagtat tgattttgac tgcaaaagat
    24781 agtttggaag ataagattga aggatttgaa cgaggtgcag atgattatct aacaaaacct
    24841 ttctatcgag aagaactgat catgcgcgtg aaagcattat tgaaacgctc gctaggtctc
    24901 tttgatgaaa atgttctgaa gtataaggat atcagttgtg atttaaaaag caatgaagtc
    24961 ttgtataaag aacaagtttt gcccatacaa ggaaaagagt ttgaattgct cgtttatttt
    25021 ttacaaaata agggaatcat tttgacaaaa gagcagatat ttgaccggat ctggggattt
    25081 gattctgata cgacgattac agttattgaa gtttatatga gcaacttacg aaaacatctg
    25141 cgaagtactg gattggataa agaaatcaaa accttacgta atgtcggtta tatactgcaa
    25201 agggtgtgat gcaatgaatg gagatattac acgaaagcaa cgtagtcgct tttttgcgac
    25261 aaatgtagca gcatttgctt ttatcttttt tcttttggga ttcattactt tacagatatt
    25321 aaaccaatct gcatacagag aaacagatct gtcattagag aaaataaatt ttgattctcg
    25381 aacagtacaa ttagagatac aaagatatca gcaaggcgat ccctttttaa acccgactca
    25441 aacggaacaa aacagaacaa acatggaaca gccattaatg gaaccatcaa atgaccgttt
    25501 taacactcaa gtgatcttgt ggtctaaaaa tggtgagata ttgaataaag cagctattgg
    25561 tgggcgtttc aaccaaatca aagaattaaa aatggatacg aaaaatctga ataccatcca
    25621 aaatattgaa ttaaatgaag acagtggctc atctgccctc tctttccgtt cgattacgaa
    25681 aaaagcggag acgaatcaag atggcgttgc ctacatccaa attttagaaa atacaaatca
    25741 aatcaagaat tcattagcga cttttcgcac gattatgatt ttgtgtatga ttgttttttg
    25801 gattctctct attggtatca gttattactt gtctagtcta agcatgcgcc ctattattct
    25861 ttcttggaga agacaaaaag aatttgttga gaatgcttct catgaattgc gcacaccgtt
    25921 aacgattatt caaaatagtt tggaacatct ttttaccaag cctaatcata ctattattga
    25981 agaatccgaa agcatcgctc aagcattgtc agagacgagg cgcctcactg gattgacttc
    26041 ggatttgctg acaatcgctc ggaatgattc tgatcagcag ctgctttcaa agcaaatgat
    26101 caatacacaa gaatatatcg aacaacttgt taaaccattt caagagatgg ccatcataga
    26161 tggaaaagag tttattctcc ataacgatgc aacattagaa gtaccaattg atgaaaaaaa
    26221 aatccatcaa gttttggtta ttttgctgga taatgcatta aaatatacga atccagaaga
    26281 taagatcatt ttggattcat ctgttaacca taaagaatgg ctgattcacg taaagaatac
    26341 tggcccttct atcagtgaag aagatcaagc aaggattttt gatcgatttt atcgggaaga
    26401 tcaatctcgg gcgaaagaga ctggcggata cgggcttggc ttggcaattg caaaacaggt
    26461 aatcgaacag catcatggac agatttctgt atccaattat cttccacaag gagtcgattt
    26521 taaagtccaa ttgccgttga agcctaaaaa ataatgctta tccctaaaaa agggctgtga
    26581 caaaaatctt gtcacagccc ttttttgttg cgaataaacg gtgttccaga agtagcttct
    26641 tcggaaataa gccgaaattt ctttaagctg accacttctg tcacaacctc tttagcttac
    26701 gcttacgatt ttttattgcg gtcttcaatg tgtacatcac cgcttgtgtc aatatccaat
    26761 tcttctcggc taacatcttc tgtcactttt tcaacatctt catgttcttc tttatgaatc
    26821 ccaacttctt cacgaataac tgtatgtttg cttacatcta cttgctcttc tttgattggg
    26881 atagtaatcg tgtcatcttc caatttttcg tctgttccct gtgaagattg atctgttact
    26941 ggtttgcgtt cgatgacgat ttcttcacgt ttgaccggta cttctaccgt ttcagtatcg
    27001 ttgaccacat gtttgtggat gtcgacttct ccagttgtca catcatgtgt atttacatct
    27061 aatttttctt cttttagttg aattgtatca tcatctagat ttggtttgcg atcgatgtct
    27121 tcagtcttgc ttgtacccat tgtatcagtc tcgccaggta cgtccatcgg atcagttcct
    27181 ggtgtcatat tcaatggatc cgttgtattt tgaaagcctg tcgtgccacc tacgtccatt
    27241 ggatctgttc cagtgccagt ttctaatcca gtccccattg tgcttgctgg gctaacagta
    27301 tcttgtgtat ccattgtatc ttctgttgtt tctggctgac gatagccttt tactgtgatg
    27361 acaaattttc catcagaaat atctcctcta tattgatata aaggatcatt ttctggtgta
    27421 gccgtctcag aatcataggt atcaaaagaa aaagtatctt ttattttttc ccataaagaa
    27481 cggtcttctt caccatccat ccgattttca tctgtttcaa catctatacc agacaatccg
    27541 tcaaatccta gtctagatgc tgcttcatca gtagtataaa taacgatatc atctcgttca
    27601 tacccttcgt tacgcaaccg ttcaattact gataatgctt cttccctcgt actatagctt
    27661 ccgatgaccg ttaaattttt ctcttccatg taaattcctc ctagcaaata gatttatgat
    27721 tggtatattg ttacttataa atttattcta taggagacga ttgttttcta caaatattta
    27781 gattggaatt tgattaaaac aatttaatt
//
LOCUS       DADVXE010000034        26766 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.034, whole genome shotgun sequence.
ACCESSION   DADVXE010000034 DADVXE010000000
VERSION     DADVXE010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.034"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(26..1957)
                     /locus_tag="KB913_001570"
     CDS             complement(26..1957)
                     /locus_tag="KB913_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6819937.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="KB913_001571"
     CDS             complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="KB913_001571"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBB6819938.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2886..3638)
                     /locus_tag="KB913_001572"
     CDS             complement(2886..3638)
                     /locus_tag="KB913_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6819939.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3797..4006)
                     /locus_tag="KB913_001573"
     CDS             complement(3797..4006)
                     /locus_tag="KB913_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819940.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4017..5344)
                     /locus_tag="KB913_001574"
                     /pseudo
     CDS             complement(4017..5344)
                     /locus_tag="KB913_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5480..5635
                     /locus_tag="KB913_001575"
     CDS             5480..5635
                     /locus_tag="KB913_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819941.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(5709..6296)
                     /locus_tag="KB913_001576"
     CDS             complement(5709..6296)
                     /locus_tag="KB913_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBB6819942.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6379..7629)
                     /gene="clpX"
                     /locus_tag="KB913_001577"
     CDS             complement(6379..7629)
                     /gene="clpX"
                     /locus_tag="KB913_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBB6819943.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALSAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7876..9165)
                     /locus_tag="KB913_001578"
     CDS             complement(7876..9165)
                     /locus_tag="KB913_001578"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBB6819944.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9319..10251)
                     /locus_tag="KB913_001579"
     CDS             complement(9319..10251)
                     /locus_tag="KB913_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819945.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10408..11067)
                     /locus_tag="KB913_001580"
     CDS             complement(10408..11067)
                     /locus_tag="KB913_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBB6819946.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11070..12095)
                     /gene="sppA"
                     /locus_tag="KB913_001581"
     CDS             complement(11070..12095)
                     /gene="sppA"
                     /locus_tag="KB913_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBB6819947.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12108..12398)
                     /locus_tag="KB913_001582"
     CDS             complement(12108..12398)
                     /locus_tag="KB913_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819948.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12807..14612
                     /gene="glmS"
                     /locus_tag="KB913_001583"
     CDS             12807..14612
                     /gene="glmS"
                     /locus_tag="KB913_001583"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBB6819949.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14684..16039)
                     /locus_tag="KB913_001584"
     CDS             complement(14684..16039)
                     /locus_tag="KB913_001584"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBB6819950.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16063..17232)
                     /locus_tag="KB913_001585"
     CDS             complement(16063..17232)
                     /locus_tag="KB913_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819951.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17229..18116)
                     /locus_tag="KB913_001586"
     CDS             complement(17229..18116)
                     /locus_tag="KB913_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBB6819952.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18305..21997)
                     /gene="nifJ"
                     /locus_tag="KB913_001587"
     CDS             complement(18305..21997)
                     /gene="nifJ"
                     /locus_tag="KB913_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBB6819953.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22196..22717
                     /locus_tag="KB913_001588"
     CDS             22196..22717
                     /locus_tag="KB913_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBB6819954.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(23416..23973)
                     /locus_tag="KB913_001589"
     CDS             complement(23416..23973)
                     /locus_tag="KB913_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819955.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(24152..24763)
                     /locus_tag="KB913_001590"
     CDS             complement(24152..24763)
                     /locus_tag="KB913_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819956.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(24876..25133)
                     /locus_tag="KB913_001591"
     CDS             complement(24876..25133)
                     /locus_tag="KB913_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819957.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(25730..26008)
                     /locus_tag="KB913_001592"
     CDS             complement(25730..26008)
                     /locus_tag="KB913_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819958.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(26042..26293)
                     /locus_tag="KB913_001593"
     CDS             complement(26042..26293)
                     /locus_tag="KB913_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819959.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         7558 a         5767 c         4584 g         8857 t
ORIGIN      
        1 aaacccagcc tcttcttttt tatttctatg cttctgctac tgcaggagct tttctcaata
       61 aaccataaat cacaccagat acgactgctc cgatagcaat aaacaccaaa tacatgaccg
      121 ggtgactcag taagaataca acgaaaatcc cgccgtgagg agccagtaat ttgattccga
      181 aagctccgac taatccgcca gttaaagcag aaccaataat aaaacttgga atggcacgaa
      241 tcgggtcagc tgctgcaaat ggaatcgatc cttccgtgac aaacgatagt cccatcacga
      301 tgttcgtcaa accagcatct tgatctgttt tgctgaattt attcttaaac aaacgtgtag
      361 caacgaaaat tgccaatgga ggtaccattc ctccagccat aacagaagcc atcacgacac
      421 ttccgccagt tgcaacagtc gtagctaaag ttgctgtacc aaacacataa gcggctttgt
      481 tgattggacc gcctaaatct gccgccatca ttccagctaa taatgcacca agtaaagcag
      541 cattcgaacc actcatactt gtcaagaaac cgttcaatgc atcattgatt gctttcatag
      601 ggacattgac cagcaacatc aagaaaccag taatcagtaa gccaaacact ggataaaaga
      661 ggatcgtttt aattccatcc aatgattttg gtaagttctt gaataattta cgtaaaaata
      721 cgatgacata accagctaag aatccaccaa tcagtgcacc taagaatcct gcaccgcctg
      781 tattagctaa tgcaccagca gcaaatccaa cgatcaaacc agggcggtca ccgatacttg
      841 aagcaataaa tcctgctaat accggcagca tgaaaccaaa tgcagcttgt ccgatttggt
      901 tgaaccagct agcagcttga ttgtaattcc ctagatttga taattgatca tgtggcacgc
      961 caataaattg gtcgatcatg aaagaaagcg caatagcgat tcctccacca ataacgaaag
     1021 gtaacatgtg tgatacgccg ttcatcaaat ctttgtaaat tctttgtccg atagtaccat
     1081 ccgcatttcc ttcttctgaa ctgctttctt ttccatcacc atggaatact ggtgcagtac
     1141 cactaagggc tagattgatc aactcttctg gtttacggat accatcactg acaggacgat
     1201 tgatcagttc ttttccgtca aagcgattca tctctacttt tttgtctgct gcaacgatta
     1261 caccttctgc acgggcgatg tcttcagcag tcaatcggtt tttgattcct tctgaaccgt
     1321 tcgtttcgac tttgatctcc acacccattt ctttcgcttt tttcttcaaa gcatcttctg
     1381 ccatgtaagt gtgagcgatc cctgttggac aagctgtaac ggcaacaacg aattttcttt
     1441 ctggatgagc agaagcttct gcagcttgtg tttcttgttc tgctttttct tctgcttctt
     1501 tttgctcttc agctgtttgg aacaagtctt ggacttcttc tggtgtattt gcttctttta
     1561 attttcctac gaaatctgca tcaatcagca atcgagatag tgctgctaat gcttgcaaat
     1621 gtgtgtcgtt tgcgccttct ggagctgcga tcatgaaaaa cagataagtt ggctgtccgt
     1681 ctaaggcttc ataatctact cctttttggc tttttgcgaa taaaactgtt gcttctttaa
     1741 ctgcactgtt tttcgcgtga ggcatggcga ttccatcacc aagacctgta gaagtttgtg
     1801 cttcgcgggc tagaattcct tctttatatg tttcgatatc ggaaatccgg ccggcatcaa
     1861 acattttttg gaccatttca tcgattgcgc cttttttatc agtcgcttgc aaatccatga
     1921 tcatcgcttc tttgaccatt aaatccttga tattcatgat tatcctcctt gaaactaatc
     1981 aatttttgtg atttcaactt ctggcagcaa ctcatcaatc aattcgcgag ctgccaagtc
     2041 atcagaaaaa gctgttgcgc ttccgcaagc aactccccat ttaaaggctt cgattggatc
     2101 tttcgtacgg ctgtaagccc caataaagcc agcaatcatt gaatcccctg cacctactga
     2161 atttttcaat gggcgaacta atacattcgt tttataagtt ccttgttccg tgaagagcaa
     2221 agcaccgtct ccagccattg agatcagcac attctgtgcc ccttcagcta gtaatttttt
     2281 cccatacgga atgatttctt ctacagattg gaaggttgtg ttgtaaagct cagctaattc
     2341 gtgattgttt ggtttgatca acaacggttt cttaacaagt gcatttttta ggtcatcacc
     2401 tgttgtatca atcacgaaat ctgcaccttt ttctcgaatg atatcaatca gttcttgata
     2461 aaatcctttt cgcaggctag ctggcgcgct tcctgacaat acgacgatat ctccttgtcc
     2521 tactgttcct aatgcttgct tcaactcatc gatttcttca tctgaaatag atgggcctaa
     2581 gccattgatc tcagtttcag tgtctgattt tagtttgata ttgattcttg tatcttcttt
     2641 tacggttgtg aacaaagact ggatttgttc tttttcaagc cacttcgaaa taaattcgcc
     2701 agtgaaccct cctaaaaacc ctagtgctgt agattgagaa tcgatccgtt tcaaaatacg
     2761 ggaaacattg atcccttttc ctccaggtaa cttgaagtct tccttcattc ggttcaaatc
     2821 gcctagtttt aacccatcta cgcgtacgat ataatcaatt gatggattaa gtgttactgt
     2881 gtaaatcatt gtattgcctc cttaattgtt gtcttttcac ggaattcatt aacgaattct
     2941 aatggacaac gctcggttat gatcgtggct gcttccaaag gtgcaacaga ggtgaaggac
     3001 aactggttga atttggtatg atcaatcaat acaaatgtct cttcggaatt tttcatggct
     3061 aaacgtttaa cagctgcctc ttctggatcc ggagtcgtga atccttgttc aagatgggca
     3121 ccgttcattc ccataaatgc tttattaaaa tgaaaatttt ttagttgttc tatcgcatta
     3181 gatcctaaaa cagcattagt tgccagcttt atcgttccac ctaaaataat ggtagcaagc
     3241 tccaaatcaa ctaaatttgc cgcatgttga acggaatttg tcactactgt gatctgtttt
     3301 ccttgcagaa aaggaatcat ttctaacgta gtagagccag cgtctaaata aatgacatct
     3361 tcgtcattaa tggtttcagc tgccgatttg gcgatttgct gtttttcgtg aacgtttttg
     3421 agtgattttt cactcatatt ctgctcaaaa ttcaataatt gctctttctt agctccgcca
     3481 tgaactcttt ctagaaaccc actattctcc agctcttgta aatcacgtct tatcgttgat
     3541 tcagaagcat tcaaaaggtt tacaagatct tgtgatttca cgattttctg ctgttcaagc
     3601 aagtctagga ttttttgtct gcgttcctct gtaagcattt tcacgatcac ctcaatacaa
     3661 ataatagcat attttttttc tactagcaat ataaatcagt caaaaacgtt cataaaaatt
     3721 ataaatcagt caaaaaaaaa taaaaaacca gtcagaaaga ctggtttttt atttttttgt
     3781 ctatcatcaa gccgttttat cgttttttat tttcgcttct tgtttttttc atataaacag
     3841 aagcaggttt tctttcctta tgaagaagat aataataaag tcccatcccg ccaaacatga
     3901 ccaaaaaacc gatgactgat cgaataggaa aattaggaac aaaaaagaga cagacggata
     3961 ataatgatgc cggaaccatt attcgataat agagttgttt atccattttc ttcacctcat
     4021 attttttgta aagtaatcaa ttgttctaat tctcggtaat ctaaaaattg cacacgcaga
     4081 tgctgctcac ctttcttgac atcgaattgg atacttcgcc gctttttctt tattcgtttg
     4141 aaggtaacat cagagagtct atgtttgatt tcctttaacg gtaattctga cagggattct
     4201 gaaggaacat agattcttaa ggataaaaga tactcttgat atttttcatc tgttacctct
     4261 acttctagat attccctaat ataataacaa taagcttcga ttccattatc caaagcaaca
     4321 gtcggatcga taactttata gcacatcatg cgtgatcgat tctcgtcaac ccaaggaaaa
     4381 tacgcctgag catttagtgt tccgcgaaca cgcctttctt tataatctcc ttgttggata
     4441 tcataacttt ttgttacaaa aaatgaagca ttctttttag gaacaggttg catttgtgca
     4501 ttctgatact ggacagattg gatcgtatgg tcagtgtaaa tgtattcaac gaatggcggt
     4561 ttcaataaac cgacaccatt gtcccaagca agatgatcaa acccaagctg gtccctaaaa
     4621 taggattgaa acatttgatt gtttggcttt tgccagttaa aggggtctcg ataaagctgg
     4681 atacatatga cttcgttttc taattccttc actttttcta cttgttggat gtcgagaaaa
     4741 atcggtttag ggatgatttg atgataatag cgactataat acatttccca acacgaagtg
     4801 aaacataaac cttggtaaaa aagatcgtat cctggaaatt ggttgcaatc gactactact
     4861 tccccgtttt gttgtttcat tttaggtaaa tgttcgattt catccttttt ctcaaacaat
     4921 agccgttgag agatctgttt tgtattgtga tagataaact cgctataagc tcgcatatag
     4981 gcgaacaccc catgagcaat catttttttc tgaatgaagt ctcgaatcaa aaattgcttt
     5041 tctttgaaaa cagagataga caatacattt tttatcaata attgattatc ttccaagcga
     5101 aaactacatt cgttctcgtc atttcctaca actaaccaac tttcgtctct taccgatgct
     5161 agcattattt tttcttgaag ctttcgaaga tcatacggat ccgcttgttg tgtgaaagag
     5221 cggataaatg ttggctggat caacagacgt gtcaaaatag cccaatcgct tatttcctgt
     5281 ttttttcttc ttcatttaag tctgtgagct ggatagtcat caataattta tcttcgccaa
     5341 tcattttctc acctctttca aatcttttta taatttaatt ataaccaatg ataaagaaaa
     5401 actaaaactt tatgtcttag aaaccaattt ggacgattac atgatagact aagtaaaaag
     5461 aaacaaagag gtgtttacaa tggggttgaa atttgaacgt acagataatt tagataaact
     5521 tttcgaatca tttgctgtcg atccggaaaa aacagttgca ccaaaagaag agatcgatcg
     5581 atttctaaaa ccacagccac aaaatgaaaa gaaaaaagac aagaaacaaa agtaagttaa
     5641 gctcaaaaaa agacttacca gccaaacttt tatgaaagag tttgactggt aagtcttttt
     5701 tattcttttt atgattcaat tgcttgttcg attgctgccc acgcttcttc ttttccctgt
     5761 tttgtaacgg aagaaaagag aataaacgtg tcattgcgat caaaatccaa cgcttttttg
     5821 atttcgctct catgcttgtt ccatttacca cgagggatct tatctgcctt agtggcaaca
     5881 acaattacag ggatatcata atacttcaaa aattgataca tctggatatc ttcttgagaa
     5941 ggcttatgac gcaaatctac taaagaaacg accgcacgta gctggtctct agtcgttaaa
     6001 tatgtctcga tcatctttcc ccattttgct cgctcagttt tggatacttt tgcataccca
     6061 tatcccggaa catcgacaaa atgtaatgcg ttctcgatca aataaaaatt caatgtctgg
     6121 gtctttcctg gcttaccgga agtacgggct aaattctttc gatcaatcaa tgtgttgata
     6181 aaagaagatt tccctacatt tgatcgtcct gccagagcta tttctggcaa ttgtgtatct
     6241 ggatattgtt ttggtgccac tgcacttatg ataatttcag cttgatggac tttcatggtc
     6301 tctctcctta acaaggtgat gaataaagca agcggctgtc gcaaaagcca aaatgacttt
     6361 tacggcagcc tcttttcatc aacccgcttt tttctctgaa tctttataga ttactgttgg
     6421 ctcaccagac aattcagctg cttcttttgt gataatcact ttttcgatgt tttcatttga
     6481 agggatatca aacatcacat ccatcatgat ttcttcaatg atggaacgaa gtcctcgagc
     6541 accggtattg cgttcgattg cttttttcgc aatggcactc aacgcttcag gttcgaattc
     6601 aagttcggta ttatctagag aaagaagttt ttgatattgt ttgactagcg catttttcgg
     6661 ctcagtcaag atccgtacca gatcatctgt tgtcaatttc tctaaagctg ccataacagg
     6721 taatcgtccg ataaactcag ggatcaatcc gaattttagt aaatcttcag gaatgatatg
     6781 ctgcatgaca ctttcgtctt cagaaagttt ttggttttgt gtaccaaatc caatcgtctt
     6841 ttcgcccata cgattcttca caatcgtttc gatgccatca aatgcaccac ctacgatgaa
     6901 caatatgttc gtcgtatcaa tctgaataaa ttcttgatgt ggatgtttac gtccgccctg
     6961 aggtggcaca cttgcaacag ttccttctag aattttcagc aaggcttgtt ggacaccttc
     7021 gccggaaacg tcacgagtaa tagatacatt ttcgctttta cgcgcaattt tatcgatctc
     7081 atcaatatag atgatccctt tttctgcaag ttccacattg taatcagcag attgaagcaa
     7141 tttaagcaaa atgttttcta catcttcccc cacataacca gcttctgtca aacttgtcgc
     7201 atctgcgatt gcaaaaggta cattcaatgt ttttgctaat gtttgtgcta aaaatgtttt
     7261 accagaccct gtaggtccga tcaagcagat attgcttttt tgcagttcaa catcatctgt
     7321 gttttcttgt gcttgctgat tgacacgttt atagtgattg tatacggcaa cagctaacga
     7381 gcgttttgcg cgatcttgtc caatcacgta gttattcaat acttcaagaa tttctagtgg
     7441 tttagggact tcagtgaatt cgcgtacagc ttcttcataa aattcttcat caatgatttc
     7501 tttacatagg tcgatacatt cattacagat gtagacccct ggaccagcta cgatcttttt
     7561 cacttcttct tgggttttcc cgcaaaaaga acagcgtacg gtctcattgc tacttggatt
     7621 gtcatacatg gtcttcaccc cttaacttgc aaaaagtatg caagaaacta tcaaagactt
     7681 tacagtcttt tactatcata acatagttta gtaaaaagaa aaagtgttta acaaaggatc
     7741 aactgaccta tacctttgca ttttttactc ttaacaaaaa ataaggaact gtgacaaaat
     7801 cgtgtcacag tcccttattt cgaataaaca attttctaga agtagcttct tcagaaatga
     7861 tttattactt gatttctatt ctttcgcttc tgtcgctgta cctgtgatca attcgattgc
     7921 ttttttcatt gtcacatcat gttccagcat atcttctgtc aacacgcgtt tgatttgttc
     7981 gattggcatg ttgtatgttt ctgataattc ttggatttct gcattgattt cttcttctgt
     8041 tgcttgaaga ttttcagcag ctgcaattgc ttcgatcaca agatttgttc ttgtgcgcat
     8101 ttctgcttca ccttcgaatt gtttatgcaa gtcttcttct gtagaaccag ttaattgata
     8161 gtacatttca ggagagatac cttgacgttg catgttgttc aagaattcgt ccattgaacg
     8221 atgtacttca tcatgaacca tcacgtgtgg caattcaacg atttctgcgt tttcaacagc
     8281 catacggatc gctgcttcat cttttgcatc gtccgctgct ttttcttttg tttctactaa
     8341 ttctttgcga tatttttctt tcaattcgtc taatgttgat acttcgtcat caacatcttt
     8401 tgcgaattcg tcatctaatt caggcacttc ttttgctttt acttcatgga ttgtcacttt
     8461 gaagactgct tcttttccag caagatcttc tgcttgataa tcttctggga aagttacatt
     8521 tacatctaga ctttcacctg atttatgacc aactaattga tcttcaaaac ctggaatgaa
     8581 tgagcctgaa cctaattcaa gtgagtaatt ttcgcctttt ccgccatcaa acgcttcgcc
     8641 atctacaaag ccttcgaagt cgattactac tgtatcgcca ttttcagctg cagcatcttc
     8701 tttgataact aattcagctt gtgcttcttg ttcacgtttg atacgtgcat ccacgtcagc
     8761 atctgttact tcacggtctt gtttttcaac aactagatct ttatattgtc ctaattttac
     8821 ttctggtttc actgttactt cagcagtgat tacccagtct tgaccttttt ccatgctttc
     8881 aacatcgatt tttggttgag aaacaggatc gatgccagct tctttgacag cagcttcata
     8941 agcttctggt aatacagcat tcaatgcatc ttcatataaa gcttcttcac cgtacatacg
     9001 gttgaatact tgacgagaaa ctttcccttt acggaatcca ggtacgttca agcttttttt
     9061 cactttatta aacgcagttg ttaatccttt ttggatttcg tcttgcgcaa tcgtaaattt
     9121 taaaacacca tcattcgtgc cttttttttc aaatgttgca gtcatttaat tccctccgag
     9181 tttagaaatt cattttatac atcaaaaacg tttcatgcat acctttaaat agtacactaa
     9241 ccctttcaaa ttgtaaacat attgaatgga tagaatcctt gtttttcata acatttttat
     9301 ctttttcact gataaaatct aatggaagaa gatcatttgc tgcaaaattt tttctctttt
     9361 ttttaaaaaa tcttgttttt catcttctgt accttcatac atcgtttttc ctgtacacgc
     9421 ctctacagtc agttgaaacc agcgcttcgg gtcttcgatg tatgtatcat agacaggata
     9481 aacaattgca gattgcaacg tgaattcttc ttttaacacg gaactaagca gcgcatcttc
     9541 attcccgtaa cgatctgaaa atacacataa ttgctggtaa cttgcctgct gctgcggctt
     9601 tggcagatct tttggtatga ctttgactaa cttttcttca atcgtcaaat agaaaacagg
     9661 atggcattcg ttcaattgcc taagtgtctc cagtaatttt gcccttgcta aaatatggac
     9721 ctctggcgat acaataagtt tactcgctgt ttggataaac tcatgataag gaagctgttc
     9781 gatctcatca atagacgcaa gctgacgtgc aggttccaac gaaggaagtt cctccgattt
     9841 attgtggagt gccttgatct tctgcctctc catttgtccg gataattctt ctgcaaattg
     9901 gattttttca atgacccgct gctcgaaagc ttcataaaaa tctgtacttg ctatcaattt
     9961 tctagcatat aaaaaatctt gtgtactgat taacaagtca aaataaaatt cagcaaactc
    10021 ctcattttga agatactgtt tttcatgcaa gagtgcttgc ttcaatgctt cttttttctc
    10081 gtccaactcg taaagacaaa aaacaagcag gctattagcc tcaaagcttt ctttcaactc
    10141 gtaagctcgt tgaaataatt cttttgcctg ctgatattgc tggtttgcta gtgcttgttg
    10201 tgccactcgc attaaattct catatttttc tggaaaatca atcggcttca cgcagtgtcc
    10261 tcctcttgct catattcagc tcatgttcaa tagtagcaaa acaaaaaaag catgacaatt
    10321 aaaaataact gaagcaccct ctaaaagcta gattttagat ctgactttta gaaggtgctt
    10381 tcaactgtta ctgcttttta ttgctcatca gctgttgact tcctggttga acgctttgat
    10441 cagattgatc gtaacaacac ttgtattagt gaaaaaatcg cccagatgtt gctttttctg
    10501 attaaagact gctggaagat accctaacat cagcaaagga aattttagaa tgaaccggca
    10561 agcaccttct ctaactaaaa cggttgacca gctaagttct tcttcatcaa agctgatgac
    10621 tcgaatacca aagatcattt tcccaatcgt ttggccatga ttgaatttcg tcaataaaat
    10681 aaaatacgct agataaataa gtaaggctgt gaatccgtag agactcagat aagaatctga
    10741 aaaattaagc caacctagat ttttggcaat accaagtgtt aaacgcgtaa tagctccgat
    10801 acacaaaaga tcgaccaaga aggcaaacat tcggataaaa aaacctgcat agaaatactt
    10861 aggaaaatca tttgcttttg gcggttcatt tcttgtgtcc gtatactttt tccatttacg
    10921 ttgtttcttt ttgatttctt cgggcgtcaa aggctctctt tcaaaagagc tcagtacctt
    10981 ttgggaaaag ttggagtcag gtcctacagc aggctgctgt tgcttatctt tttcttgttc
    11041 cttattttca tttgaaagct ctgacatgct tactcacctc cgtaataata cattgctttt
    11101 ggtgattccg ctgtccctag attctcaaga acggataaga tctgactagt ctcagaaggc
    11161 ttcaatccct ggaattctgc tagtttactt cctaaccatg tactagcaaa cccagatggc
    11221 gtggaagaat attctactag ttccgcatct tcaagctgtt gttcctttcg tatagctttt
    11281 aaagcatctt caggaaatcc caattcatcg actaaaccta cttcttttgc ttggacacca
    11341 tcataaatcc ttccatcagc aatttttttg acttcttctt cagatttatt ccgtccctcg
    11401 ctgacgattg ctacaaaacg actatatgcg ctgtcgatat atgcttgaag caccgcttct
    11461 tcttcttttg tctctggtcg cgttcctgaa cccatatctt tcaacgctcc gcttttaact
    11521 gttgtatctt ccacacccag tttttctaga agtcctgaat aattcaatcc tgacatgatc
    11581 acaccaattg agccggtcac tgtttcttct gttgcaaaga ttttatctgc ttgagcagaa
    11641 atatagtagc caccgctagc tgccatgttt ttcatgctga catacattgg gatatcatgt
    11701 tctttacgaa tcgtatccaa tttcttagcg atttccgcac tttcgtagac accgccacca
    11761 ggagaattta cttctaaaaa gatacctttg actgttggat cttcttcaat cgccttcagt
    11821 tgttccataa aatttttatg attgtaacct tcagaagcaa ataaacctga agaccctccc
    11881 gcagcaatcg ttccatctac tgataatttt acgatttttt gcgtactgtc tccctcttcc
    11941 aacacatttg gagctagttc ttcatcccca tataaccaac tgttcaatcc ctcaatttga
    12001 tcgttttcct gaggcttagt caaactagct gaaactaacg aaaccacaaa taatcctgca
    12061 gcaatcagaa ctgctgccca acgtctttta ttcattcttt ctcctttcta atacaagttt
    12121 tttatgacga tcacagtttc tgactgctca gaagtgtcga accgctctgc tttttcttcc
    12181 cgcgcatacc cggaaaacga ctcttttgtt aattcatctt ctaccgtaaa ctcacgagct
    12241 tgagcaactt ccaaggcatc aggtgcgatt tcttggatgc tatcccagcc agtatctaaa
    12301 aatattttcg tatcatctga tacaccagct gatgcttcga atttggacaa ttgttttttt
    12361 aacattccca gtgtcatgat ctcaattttt gaatccattt ttactcctcc tctatccgat
    12421 tactttctat tgtaccgaac tcctgaaaaa gatgatagat aaaaacccat tattttttga
    12481 cataaaaagg acatttgaca aagaatttga tatataccaa tttatttttt attctttttt
    12541 tgttgacaag aacattcgca aaaggttatg attttaaatg tttccagata aaaaacaaaa
    12601 aggaggatag ttataccttt taggatagcg ccaggtctgt gtaaacagat gacgaggaga
    12661 gggtttatcg aaagattcgg cggatggccc tagggactgc actctacaga aaatccacaa
    12721 aaaatgtctg caaagataaa acaaaaggat tttcctgcag ctggaagcat tcatacgaat
    12781 tcattataga aagtaggatg ttttttatgt gcggaattgt tggaatgatt ggattaaaaa
    12841 atgtaacacc aggattgatt gacggtctag aaaaattaga ataccgtggt tatgattcag
    12901 ctggtatctt tgtctcagat ggcacaactg attatctggt caaagcacaa ggcagaattc
    12961 aaaatttgaa aaacaaaata aatattgata ctacaggaaa tataggtatt ggtcatacac
    13021 gatgggcaac tcacgggcaa ccttctgaag aaaacgccca tccacatact tcccaaagtg
    13081 gacgcttcgt gctcgttcac aacggcgtaa tcgaaaactt tgaagaactt aaaattgctt
    13141 atttagcaaa tgaccacttt attggtgaga ccgatactga gattatcgct catctaattg
    13201 aaactttcgc gaaggatact acaacgcaag aggcgttttt aaaagctttg cgggtcatca
    13261 aaggttctta cgctttcgct ttgattgatc ggacagcacc tgatgttatt tacgtcgcta
    13321 aaaataaaag tccactatta atcggactcg gcgatggatt caatgtgatt gccagcgatg
    13381 caatggctat gcttgctcat acgaaggaat tcgttgagat tgaagatgaa gagatggtta
    13441 ccgtcacatc agaaaaagtt attattcaaa attttgcagg tgacatcgta gaacgttctt
    13501 cattcgaagc acaagtagat gcttcagata tcgagaaagg tacctatcct ttttatatgc
    13561 tgaaagaaat cgacgaacag cctattatca tgcgtcgtat cgctcaaaaa tacgtaacag
    13621 aagacaatcg tgtctctctt gatcaaaagc tggtcgatac attgtctgat agcgatcgaa
    13681 tctatatcgt tgcttgcgga actagttacc atgcggggtt agcaggtaaa cagactttgg
    13741 aaaaattgac acagattcct gttgaggttc atttagccag tgaatttggc tataacacac
    13801 ctcttctttc aaaaaaacca ttctttattt tcttgagtca aagtggcgaa acagcagaca
    13861 gccgccaagt gctggtaaaa atcaaccgtc tcggctaccc ttcacttacg attacaaatg
    13921 ttgctggttc tactctttcg cgggaagcat cctttacact gctattgcat gctggacccg
    13981 aaatcgcagt agcatcaacg aaagcttata ctgcacaaat agctgtacta actttattag
    14041 ccaaagctat cggtgataaa aaagaatttg aaacttctct tgtattcgat atcactcatg
    14101 aattgagttt agttgctaat gcgatggaat cggtcatcgc ccaaaaagat tatttagaag
    14161 agttggcaga agtatatctc agcgatacaa gaaatgcctt ttacattgga cgtggtgctg
    14221 actacaacgt ttctcttgaa gctgctttga aattgaaaga aatcagttat atccaggcag
    14281 aaggttttgc cgctggcgaa ttgaaacatg gaacgattgc tttgatcgaa gaaggaacac
    14341 cagtgatcgg aatcatcagt gaagaagtga ctggtgcgca tactcgagga aacctgaaag
    14401 aagtcgaaag ccgtggcgct aaaacactag ttattgtctc agagggatta gaaaaggaaa
    14461 gtgaccagct ggtgctacca actgtccacc cttatctaac tactctaacc acagtcgtac
    14521 cgactcaatt acttgcatat tacgcaacgc tattacgggg attcgacgtt gacaaaccac
    14581 gtaatttagc gaaatcagtg acagtagaat aataaaagaa caaggaccag tgtcagacat
    14641 ctgacactgg tccttgttct tttatttttt atgaaaatat ctcttaatcc agtccgattt
    14701 cttctttgac tactgccgcg attttatcga catagtaatt aactttctca tcagtaggcg
    14761 cttctgccat cactcgaagt aatggttctg taccggaagg acgaactagg attcttcctt
    14821 ctgatcccat ttcagcttct gcctcttcaa tcactttttt gattgccgga acatccatcg
    14881 caccgttttt atcacttacg cggatattca ctaatttttg cggatagatt gttacctctg
    14941 ctgcaagctc tgataatttc ttacctgtct gtttcatgat attcagtaac tgaattcctg
    15001 aaagcatccc atctccagtt gtgttaaaat ctaagaaaat catgtgccca gactgctcgc
    15061 cgccaaagtt ataatcgttt ttgcgcattt cttctacaac gtaacgatca ccaacttgtg
    15121 taacgacatc tttcaaaccg attccttcca ccgctttgtg gaatcctaag ttactcatga
    15181 cagtcgtaac gatcgtatct tttttcaatc gatttttttc tgccaagtat ttagcacaga
    15241 taaacatgat tttatcaccg tcgacaatgt ttccaagttc atccaccgca ataatacgat
    15301 cgccatcgcc atcgaaagct agtccagcat ctgctccttt ttcaacgacc atctcagcta
    15361 aacgttctgg atgggtagag cctacgccgt cattgatatt taacccgtct ggatttgtgc
    15421 ccattgtata aaaatctgtt tcaagatcgg caaacaaacg attaacactt gttgaagttg
    15481 ctccgtttgc tgcatcgaca caaatggtca aaccggaaag gtcaccgttg atcgtttgta
    15541 caaggaattg agaatatttc aataagcctt ctggaaattc ttctacagtt cccaatcctt
    15601 cagctgatgg acgaggcaat tcatccactt cagcatctaa taatgcttca atttctagct
    15661 cttggtcatc tactagttta aaaccatctg caccgaaaaa tttgattcca ttatcttgtg
    15721 ctggattatg agaagcagaa atcatgaccc ctgcgcttgc tttttgcaaa cgtgtcagat
    15781 aagcaacacc tggtgtagag atcacaccta gctggaacac ttcgataccc accgataaaa
    15841 gtcctgaaat cagcgcttct tctaacattt gacctgagat tcttgtatcc cgccctacta
    15901 acacgcgtgg gcgttttcct tcttcttcat gctggcttag gacataacct ccgcaccgtc
    15961 ccagcttaaa tgcaagttct ggcgtaagtt ccttgttggc ttcaccgcgt acgccgtctg
    16021 ttccaaaata tttacccata gttgtaaaat tactccttta acttaatttt ctgaggaatt
    16081 tgttctgctc atttgtgttg attcgcttgt ttctgatgtt tcttctgtac ttgtggtcga
    16141 gctgcttgtc ccagattccg aactggaaga aatggttgtt gtcgatggtt ccgttcctga
    16201 atcagcagat gaaatacttc tactcgtact tgtattttct tgtgtccgac tgctcgtcga
    16261 agcagagcta ctgcttgacg tttgcaacac gggtgtaatc tccacactaa ctgattcggg
    16321 cttgatactt aacccctctt ctactggtat ttcaatttta cgagttgttc gatgattgat
    16381 acctgagaca ttgatcggta cagcaatact gtcaccgatc gatgcaagca aatcgctaga
    16441 gccgcttact tctgcttcca gttttgaaaa actgaaatca tagctttcta ccccggcagc
    16501 tggtgttcct tgctgtatcc cataaagtcg taccgacttg cttggcttga tcgaatcagc
    16561 tctcactgtt acttgcactg gatcagagac gatacttaat acttcccctg ctgcattcag
    16621 cgcctgtatt gggacctcac tattaatccc atcatctgtg accatcgaag cgtccacatc
    16681 agctactact cgtttgattt ctgccaatgt tttgtcacct gtagtgatag agactttttt
    16741 aggactaacg gaagtatcat caagttcata tccagatggt gtgaacgttg aaggaatcaa
    16801 cgtttccaca tcgaaatctt ttattacctt tttctcaacc gttactgtaa tagtcgatgg
    16861 ttcgatcttt gctgtgacag cactgctcaa attttgaatt tttagcggaa cttcatgtgt
    16921 tccttcgccc agcttagtga tatctgctgt gacgcggaac atccgtgtat cttcgtttgc
    16981 ctctgcattc aactgaactc ggtttgcact ggaaagtttg acagtcactg cattttcata
    17041 tccatggata tagtagcgct ttgaatcata agaaatcttg atcggcaccc ccgtaactgt
    17101 ttgattatac gcttcatttc cagaaagcgt atttggaacg gactggccat ttgcattgaa
    17161 gtacagcgca atactgaaca gcaatgcaat aaaactgtaa agaatgcttg tccgtttctc
    17221 ttttgagatc atttgcgatc ccctccctta gtcataccgt ctaggaaaga ttgaatcacg
    17281 tttttcttgt tttttgtttt ctcttcagca attagttctc tacgcaagat tgccaaatat
    17341 tcttgctggg ataagccagc catcagttca ttatctaacg tgatgctgac gtccccggtt
    17401 tcttcagaga caacgatggt aatcgcgtca ctgacttcgc ttataccgac agctgcccgg
    17461 tgtcgagtcc cgaattcttt agggatcaac atactttctg atagaggaag ataggcgctt
    17521 gctactgcga tctttccttc ttttacaata actgcaccgt catgcagcgg tgtattagga
    17581 ataaagatat tgatcagcag ctccccagtg atatctgcat ctaaagcaat ccctgtctca
    17641 atatactcat ctaatccagt atgacgttcg atagtgatca acgcaccgat ttttcgcttg
    17701 gacatatatt ggatggcttt gtcaaaagac aagatcatct tctcatcttc ctgctgttcg
    17761 ctttttgatt gtttgaaaag cgaactgcgt ccaagatgtt ccagtcctct ccggatttcc
    17821 ggctgaaaaa tcacgatagc agctatcacc ccgtacgtaa tgacttggtt catcagccaa
    17881 gacaaggtgt gcagaccaat gatttccgct acgattcgga taacaataaa aatagctaca
    17941 cctttcagaa gctgaatcgc ttttgtgcct cgcagcagtt ggatcagttt gtatacaaga
    18001 taccagacaa ccagaatatc aagtatgttc accaaaaaat tcagagagaa caagtcaccg
    18061 gaaaacattt gctgccaata gtccaaatta aaaagttccc cgatttgaaa tgacataaaa
    18121 agcctctctt ctcttttgag atttcctctc tagtatatca tatgttttaa ttttagaggc
    18181 tgatatgctc gtatttttct tgagaaaaac gcataatttt caagaaaatt gcaagtatgc
    18241 gttttatttt tctctgcaat aaatattttt aaacttcaga gaattattca ttatattttt
    18301 tctgttattt ttcctttttt tcttttgtag cttgttccat ttttttacgt cgttctgctc
    18361 tggcagctct tctagcagct cttctttctt ctgcttcaag gtccgtcgtt ttttcttttc
    18421 tagtcttaac gggtacatcg atagattcct ctggttcaag tcgtttcttg attttttcta
    18481 attctcccgt cagtgcagca tagttgtaaa aacgtgtttt agcgtcgtgg acagtctttt
    18541 caaataaagc ttttgcaaga tttggatttg cgttatctag cgaggaaaag cgaacttgtt
    18601 tcctcatgaa atcaggcata gcagagaaat caggtttttt gtagtccaaa gtcattgggt
    18661 tcttgttttt ttcgaccatt gtagggttat atcgatataa tgaccaataa ccagaagaaa
    18721 cagcttcttt tgcttcttta agcgattctt tcattccgcc aagcaagcca tgtgtgatac
    18781 aaggcgtata ggcaataatc agagaaggac caggatactt ttctgcttct tcaaatgcct
    18841 tgatcgtttg catttgattg gcacctgaag caatttgcgc cacataaaca tttccatatg
    18901 tcatcgccat cattcctaga tctttctttg aagcatactt tccactagcc gaaaatttag
    18961 cgattgccga agctggtgtt gcttttgagg tttgaccgcc agtattggaa tagacttcgt
    19021 tatccaaaac aaggatattc acgtctgctc cgctggcaag tacatgatcg atcccgccaa
    19081 aaccaatgtc gtaagcccat ccgtctccac caatcatcca ttggctgttt tttacgaata
    19141 gatcctttct cttgtatata tcctccagtt cagggaaaat tgatcgttcg ctttcgatcg
    19201 cagcttgcag ttttgctgct ctttgctgcg ttccttcact ctcaaacatg tgtactaacc
    19261 agtcttccat caattctcgt agttcttctg atacttttgg caatacttct ttgattgaac
    19321 ttgccaaagc ctcgcgacga gtctgtgccg ctagaagcat accataacca aattcagcat
    19381 tatcttccaa taaagaattt gaccatgcag gcccttgacc acattcattg gtcgtataag
    19441 gagaagcagg agaagcaccg ccccaaatag aagaacagcc tgtcgcattc gcgatcatca
    19501 ttcgatcacc gaacatttgt gtcaataatt ttacataagg tgtttcgcca cagcctgagc
    19561 aagcgcccga gaattcaaga agcggttgat tgaattgtgt agacaagaca gtattctttc
    19621 ctttgactgg atttgctttt tgtcttaatg tcattgcaaa agcccaattc acagcttgtt
    19681 ctttctgttc ttcataaggc ttcatcacta aagctttttc ttttgcggga caagcctcta
    19741 cacacagacc acaacctgta cagtcttcca ctgaaacttg gatacggtat tttacgccgt
    19801 ctgcgcctcg catttctctc acgataaatc cttctggcgc ttcttccatt tcctcttcat
    19861 ctgctaaaaa tggacggatg gcagcatgag gacaaacaaa ggcacattca ttacacatcg
    19921 tacagcgatc actaatccac tcaggtactt ctaaagcgac gccccgcttt tccatagaag
    19981 ccgttcctaa aggcatttcg ccagttgtca ttccatttgc tacaagtgta ccaacagaga
    20041 gttgatttcc ttcctgtgca ttcactggtt caagtatttc ttgtatataa ccagtgttcc
    20101 ttttattgat tttttcaggc atctccaacg ttctccaatg gtctgggatc gcgacttgat
    20161 gaagcagttc ggtcgtccga tcgattgctt gtatgttttt ttctacgata gccattgatt
    20221 tatgtccata gcttttcagg gcttcttctt ttagcagcgg aagcacctca tcaaaaggaa
    20281 tgatgtcagc taatttaaaa aaagccgttt ccattgccgt attgatccgg cgtcccaaac
    20341 cgacttcttg ggccaatctc atggcattga tcgtatagaa tctaatgtta ttttcagcca
    20401 agtaacgttt taattttaag ggcagatgcg tttctaattg ttcgtcgctc caaagagtat
    20461 tcaataaaaa aatgccacct ggcttcaatc ctttgaccaa gtcatagcta tgcaggtaag
    20521 ctggtgtgtg acaggcaaca aggtccgcat gctcgacaag atacgctgaa cgtatcggcg
    20581 tatctccaaa acgaagatga gagacagtca gaccgccaga ttttttcgaa tcataataaa
    20641 aatagccttg cgcatattta tcggtgtgat ctccaataat cttgatagct gatttatttg
    20701 ctccaactgt tccgtcagat ccaaatcccc aaaacttggc ctggaatgtt tgcggttctg
    20761 tcaaatccag actttccttt ggttccaaag attgataagt cacatcatcc acgatcccta
    20821 tggtaaaccg ttttttgcgt atgcttgggt cttttttcaa ttcatcaaaa actgctgaga
    20881 tttggtcggg agtcacatct ttagacccca atccgtagcg accaccaata acagccgggc
    20941 gaagttcaga atcatataac gcactttgaa cgtctaataa gagaggttct ccacctgccc
    21001 ctggttcttt acttcgatca agaacagcaa ttgtttttac tgtatgaggc aacttttgca
    21061 cgaatgtttc cactggaaaa ggacgataaa gatggatatt caaaaaacct gttttccgtc
    21121 cgtttgcatt caagtaatca atcgtttgtt caatcgtctg tgcaactgat cccatagaaa
    21181 caatgacttc ttccgcatcg tctgctccgt aataagtcac caagtcataa gaagttcctc
    21241 gtaatcggtt gatctctttc atatattttt gaacgatttc aggtaattta tcataatagg
    21301 ggttgatcgt ttcccgttgt tgaaaatgga tgtctggatt ctggttcgta ccactaacag
    21361 tcggatgatt gggattcatc cctcgtttac gaaatgaagc taatttctcc tgattgatca
    21421 gaggagctaa ttcttcatat tccaaaactt cgattttttg aatctcgtga ctcgtacgga
    21481 atccatcaaa gaaattcaaa aaagggactt ctccttcaat agaagcaaga tgggcaacag
    21541 gtgctaaatc catcacttct tgtacactgc tttcagctaa catagcaaat cctgtttgtc
    21601 ttgcagccat cacgtctccg tgatctccga aaatattcaa cgcatttgtc gtcactgccc
    21661 gactagcaac gtggaaaaca cttggcagta gttccccagc aatcttgtac atattcggta
    21721 tcatcaaaag cagcccttgt gaagcggtat atgtagttgt cagtgcacca gttttcaatg
    21781 atccatggac cacaccagct gctcctgctt cggattgcat ttctactact tttactggtt
    21841 gaccgaatac gttttctttt cctgctgctg accattgatc tactaattca gccatggtcg
    21901 aactgggtgt tattggatat attgcagcaa tctcggtaaa tgcataagaa atatatgcgg
    21961 ctgccgtatt gccatccatt gttttcattt ttcgcatgat tcatcatcct tgttcatatt
    22021 ctctcttatt atctgttcca ttataacgta aaacatgcca tttttttctt ttatttataa
    22081 aaatatttta catgtatcta tttgaattgg tcatctaatt tttagacaaa cagtctaaat
    22141 cgttgccttt ttttgtcaga catgtataaa ctataagcga aagaggtgtt ttaacatgga
    22201 tatatcagtg attgatgcaa cgaaaacaaa tacacaaaaa ggaatccttt atggttcatc
    22261 gaatgctcct aaaaaaatgg tcgaattcat caacttagct tgtccgtatt gccgacaatg
    22321 gtttgaagaa tcttatgagc tattagaaga agcagtccaa agcgggcaat tgcagcgagt
    22381 gatcaaattg ttcgataaag aaaaagaaag cttacagcga gggaacgtga tgcaccggta
    22441 tctcacaatc agcgatggcc aaaaagcgat caaagagatc aaacaaatat tcgatactca
    22501 agacgagtgg aaacatcttt ctctccaaga agtagcggat tttgcagtag ataaactaaa
    22561 gctgacagaa caaaaagacg aacagctgag ccaagctgtc atcaacgaag ctgagcaagc
    22621 acatattcga tttgttccaa ctgtcatctt gggtaaagaa atctttgatg aatctatttc
    22681 aatagaggaa ttaaaagaat tgatccaaac aaaataaaaa aataaggagc gtgggacaaa
    22741 agtaaagaac acttttgtct cacgctctaa acacgtataa acggcggaag cagaagcaac
    22801 tccttcttat ttcttggagt taaacgcttc tgtcccagcc tccttattcc gaataaatgg
    22861 tgtccaaaag cttgcatctg ccagattatc tcatttctta tgacaagcta agcaaattat
    22921 ctccaccaaa taatttattc atatttttga cttgcgcata ctaactaatt cttaaatttt
    22981 catacaaaat ttctcaattt cccttaacga gtaatattta tgtacggtga ttctcactag
    23041 tatcccaatc actttttaag ttatcccgat ttcaattcta cttcaaaaat agttgctttt
    23101 atgtatgctg ttagttgatt agatggtcat ttgttgagct aggtcgttta ttttaaacaa
    23161 gttgtttctt tagcttatac ctatctcgtc taccaaacgc aagatggcaa acacaaatgc
    23221 atacgcatct gtatttgcca ctttgattcg tataaagcta acaactatta actcctctca
    23281 gctaatagtt gctctctttt ttattcagat tcatttttgc tgatcacagc ctagtatttc
    23341 aatggttttg aacactaaac caaattgttc cattacaaca ttcactggct gatgaaatgg
    23401 attagtagat ttcgattatt caaagcgatt ttctattggt ggatcgtgtt cccaactaat
    23461 aagacggatt ccaaacctat cgtacagatc ttctaaacca cttataaatt ttgcacctat
    23521 ttcaggtgtt ttattgcgtg gatattctat tgttacgcca ttaaatggat accaattagg
    23581 attaggctct ctttttttct gtacatctcc catagaatag ttagcacttt ctgggacata
    23641 atatattctt cgaccatcct ctaattcatc taataagata tttcgtgatc gtctatcact
    23701 tgctaaatgt agacgccacg tgcgatacca tgccatgcta cctgcatctg cagaaaatcc
    23761 atcaaataat gcaacaattg tatcttctat cacaatcctt tccccatcta cttcatattc
    23821 taatctaaaa tcaaactccc ctcgggtaat ttctggtctt ggtggcttag gacccaatat
    23881 tattctactt aaaaccgcat tcgttcccag atgaaacaca gctataacaa caataatgat
    23941 taatattttg tttctatttg ataaatttct cattattcgc acatcacctc tacattctca
    24001 catattagtt cgtaatactc ctttaatatc aaaatatcta ctggtcgtaa taatattcgc
    24061 tatgaattcc tactactcgt ataagaaagg ccaaatcatc agcttttact tgctgatgat
    24121 ttggcttgtt tctatttatc gtaattgttt tctaatcacc aaaattgtta acaatcggtt
    24181 cagatatttc ccagttgatt aaggtaattc cgtattgtgt caaaacttct tgcgcttctc
    24241 cgaaattaag tacagttctt atgtatccac tttctcctaa tataaagtct acctctcttt
    24301 taaaaccttc ctcgagattt ctaagggcta tatgtggttt taatgacatt gattgtacat
    24361 tttcccccat ataatattgc gcacttcctc gactaaaata gattcctaga tcgtccccaa
    24421 aaggtagatc ttctctacca ctagctaatc tacttctcca tcttcgttct cttttcatag
    24481 aacctgcgct gaactcacac ccgttaaact cagctatgac agtatcttca attatgttaa
    24541 tctgtccatc tagttcgtat tcaatcctaa atggaaattc tccataggtg atttccggtt
    24601 cgggtatttt aggtgagatt aatgcaaaga aaggaaatat taagcttggc aacatcaaaa
    24661 aaactcctcc tatgatcaca attcccgatg taatccaaaa tataatttgt acaattctca
    24721 ttgatccatt gtattccatt ttattccccc tattactatt catatccgcc tatctatatc
    24781 gatcttccaa tgcagagata attgcttcca taccttgatt ttttactgag ttacctatgc
    24841 gagatatcat tctccactaa ggtgcatcat attgtctatc taacatgatt aattctccaa
    24901 taggtgtata ctcctccaaa aacaacattt aatgcatctc cctcgacaac ataagctacc
    24961 atgtttgctg tatatgtgtt tgagtctaat tcataagcag ataaatttac tgtcgctgga
    25021 ttaaatataa tcgcattcgt atttatagct actgaatttg ctgcttcagc accacctttt
    25081 gaatgtccga tcattgtgat ttcaatagta ggatttacgt ggacagccct caccgtttac
    25141 cctgaccatt atagaaatcg cttacttttt tgaactacgc aacaaaggat acaatgctcc
    25201 taacttcact gtctccattt ttgtccacta aggaatataa aaaataggca ttaattcatt
    25261 taattcggtc acaacacgtt accttttaaa tcattatact gtatctcata cattattatc
    25321 aataaactat tataaaaatg caaaaaatgc tttatcaatc tattttgtaa ttggtcataa
    25381 tatcattgaa atcataccct gtatcgattt ttcctatgaa tctcgtctat ttgtgattga
    25441 cgaaaaagag gcaagacaga cactggaatg gtaattttac ccactatttt gctccaacta
    25501 tttgtaatcg tacccacttt tgaaataccg agatgatcat tttaattgat atgctgattc
    25561 ccaagcaaaa ccccaagaaa ttaaatgctc tatcgcatct agcttcttgg gttttgctta
    25621 tataaattcc aacatttaaa ttttttatgc tgttcggtct cagaaatgcc gtttttgctt
    25681 atatcacaat atcaagatgt caaattattc gtgttgccga tgactttgat taattttttt
    25741 caaattgttt attaagacta atgctgtctt tttgcagata ccaatgttcg aactttttaa
    25801 cattatcata tgatcctgca agttttaact tcttaccatt agatgttatc aaagttataa
    25861 ttaaccttgc ctttttccca ttaggatctt ttattttatg aattttctgc aggtaatctc
    25921 tcctaatggc agctattttt acctcatcag tgctgataaa ccattgatca tccacataca
    25981 tactgcctgt tatgttgtgt ttttccattt cttccgagaa cgaaaagttt aaggctcgtt
    26041 cttacttcca aagttgaatg agtccatgga ttggacttag tgtgagaatt gagaacaaca
    26101 ataagaatcc atatcctccc gcaaacatcc ctaaggctat actgtctctc catccataag
    26161 taggattaga agagaaaaga gtcaccgttt gtaataatat gaaaaggaat aatccagcac
    26221 aaacaccaaa gataacaact ccaaacattg aatttttata caatgaccat ttatttatag
    26281 gcttttcttt cattttactt ccccctactg ttctgttcac acggaatgaa ttcaaagttc
    26341 ataagccctc ctctttgaac atatgaatac gacttgctaa ctatacttta aaaaagcttg
    26401 ttttaagcgg ttataggcga gttgtaatct ctattcatct cattagcaaa taacttgccg
    26461 aaaagtctac tgaaattaaa gcagatagtg gaagaattat ttagccagga tagacactat
    26521 ttgtgaaaca catgtcttta cttttgaaat tctatgatga aaagccttgg aatacagtag
    26581 ctcttaattg gtaatacttt ttccattata aataacctct tttcatttta tatttatccc
    26641 ctctaaaaat aatatctaat ctaatatttt aaacttatat ttccctcgct gtgctaatag
    26701 agcattacta aataaataga aactagaaaa aagcattacg cctgccagaa taaaccaatt
    26761 atttgt
//
LOCUS       DADVXE010000035        26156 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.036, whole genome shotgun sequence.
ACCESSION   DADVXE010000035 DADVXE010000000
VERSION     DADVXE010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.036"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..186
                     /locus_tag="KB913_001594"
     CDS             <1..186
                     /locus_tag="KB913_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6819960.1"
                     /translation="DIYKKLASKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADF
                     YRKMQIINYQPLAETHA"
     gene            complement(830..1783)
                     /locus_tag="KB913_001595"
     CDS             complement(830..1783)
                     /locus_tag="KB913_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6819961.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(1806..2561)
                     /locus_tag="KB913_001596"
     CDS             complement(1806..2561)
                     /locus_tag="KB913_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6819962.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            complement(2558..3517)
                     /locus_tag="KB913_001597"
     CDS             complement(2558..3517)
                     /locus_tag="KB913_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBB6819963.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            complement(3510..4460)
                     /locus_tag="KB913_001598"
     CDS             complement(3510..4460)
                     /locus_tag="KB913_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBB6819964.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            4610..5062
                     /locus_tag="KB913_001599"
     CDS             4610..5062
                     /locus_tag="KB913_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBB6819965.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            complement(5151..7418)
                     /gene="gshAB"
                     /locus_tag="KB913_001600"
     CDS             complement(5151..7418)
                     /gene="gshAB"
                     /locus_tag="KB913_001600"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBB6819966.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(7605..8603)
                     /gene="ftsY"
                     /locus_tag="KB913_001601"
     CDS             complement(7605..8603)
                     /gene="ftsY"
                     /locus_tag="KB913_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBB6819967.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            complement(8614..9423)
                     /locus_tag="KB913_001602"
     CDS             complement(8614..9423)
                     /locus_tag="KB913_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6819968.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            complement(9432..13013)
                     /gene="smc"
                     /locus_tag="KB913_001603"
     CDS             complement(9432..13013)
                     /gene="smc"
                     /locus_tag="KB913_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBB6819969.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            complement(13033..13719)
                     /locus_tag="KB913_001604"
     CDS             complement(13033..13719)
                     /locus_tag="KB913_001604"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBB6819970.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            complement(14067..15848)
                     /locus_tag="KB913_001605"
     CDS             complement(14067..15848)
                     /locus_tag="KB913_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6819971.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            complement(15874..16788)
                     /locus_tag="KB913_001606"
     CDS             complement(15874..16788)
                     /locus_tag="KB913_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6819972.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            complement(16815..17777)
                     /locus_tag="KB913_001607"
     CDS             complement(16815..17777)
                     /locus_tag="KB913_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6819973.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            complement(17777..18721)
                     /locus_tag="KB913_001608"
     CDS             complement(17777..18721)
                     /locus_tag="KB913_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6819974.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            complement(18722..19726)
                     /locus_tag="KB913_001609"
     CDS             complement(18722..19726)
                     /locus_tag="KB913_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6819975.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            complement(19994..20236)
                     /gene="acpP"
                     /locus_tag="KB913_001610"
     CDS             complement(19994..20236)
                     /gene="acpP"
                     /locus_tag="KB913_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBB6819976.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            complement(20358..21359)
                     /gene="plsX"
                     /locus_tag="KB913_001611"
     CDS             complement(20358..21359)
                     /gene="plsX"
                     /locus_tag="KB913_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBB6819977.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            complement(21408..23444)
                     /gene="recG"
                     /locus_tag="KB913_001612"
     CDS             complement(21408..23444)
                     /gene="recG"
                     /locus_tag="KB913_001612"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBB6819978.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            complement(23561..25243)
                     /locus_tag="KB913_001613"
     CDS             complement(23561..25243)
                     /locus_tag="KB913_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBB6819979.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            complement(25295..25657)
                     /locus_tag="KB913_001614"
     CDS             complement(25295..25657)
                     /locus_tag="KB913_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6819980.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            25927..26115
                     /locus_tag="KB913_001615"
     CDS             25927..26115
                     /locus_tag="KB913_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBB6819981.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
BASE COUNT         7178 a         5698 c         4627 g         8653 t
ORIGIN      
        1 gatatttata aaaaattagc ttcaaaaaaa acgaatagtt ttggattgat attaagcgag
       61 tataaaatca aagcagaaga gagttatttc tatcaattac taaaacggtg gagtaagctt
      121 cccgccgatt tttatcgaaa aatgcagatc atcaactatc aaccgcttgc tgagacacat
      181 gcctaaatag aggttgtgaa atcagtgctt tgagctaata ccgaaggtca gctgattgaa
      241 cattgtttag aagagattgt gacaactgcg atttgctttg agtaataaga acgctggaca
      301 gaaaatagct tctcatattt tctagtctag tgggcttatt gccgagaagc agcagatgga
      361 acatcgttta gaagagattg tgacaactgc gatttgtttt gagtaataag aacgctggac
      421 agaaaatagc ttctcatatt ttctagtcta gtggacttat tgccgagaag cagcagatgg
      481 aacatcgttt aaagaagaga tcggtacaaa ataaaaatat ctaaatttaa gttttatcta
      541 agtttcgctt tgtacctttg attcaaatca aaggaggcga tcttgatgct gaaaaaatgg
      601 atcacactat tttttgccac tccccattct agaatcaacc cgtatgatgt agataatgaa
      661 ttcacgttga aaaaagattt ctcaaataaa taaaaaccat ccgtaaaatc atcaatacga
      721 ttttacggat ggtttttgat aacttctttg aggataggct cttgctattt aagaatgtaa
      781 gaaacattat tgttacatag tatgagagtt taatcctctg ttatttatgc tatttaaatg
      841 cttgattcac atcttcgatc atcagtttca ttgattctaa accgcccccg cttaaatacc
      901 agacatctgg ttcaagggag atgatctgct gatttttacc agcattcgtt tgtgctacca
      961 gttcattggc agaaatatca tctttgctgt cgtctccacc aatagctttt gttctgtcta
     1021 ctacaaataa gatatccgga tttttttcca gcacatattc ataagaaaca ctttgaccgt
     1081 gagtggatgc ttcgatttga tcatctgctt gttcaaagcc aaataaatca tggatgaaac
     1141 cgaatctaga accagatccg taggctgata attgcccttc attcacaagt gtgactagtg
     1201 cttttttgtc agtagcttct gctttctttt tcgtctgatc gattgcacta gataattcct
     1261 ctaattgagt tttagcttct tcttgcttac caaagatctc ccctaaagca gtgacatttt
     1321 gctggaaaga ttcccatgga tttttcgcat ctaaagaaag gaaaatggtc ggagcaattt
     1381 gacttagatc tttttgaaaa tctctttgtc ggccagaaat gatgattaga tctggctgaa
     1441 gctgattaat tttttctaag tctggttctt ttattccacc tgctgattct acttttttat
     1501 aggatgaaag atactcagga aggctgcttg tagctgctcc aactacctta tctccaacac
     1561 caagagcatc catcgtatct aaagaaccat tgtcgaatac gacgactttt tctggattat
     1621 ttggcacctc gatttggtct ccattactat ctgttatcgt caatgtagtt tcagtttgtg
     1681 tgctgctttt ttttgtgtct gcctgactgg tgttgttgct atttccacat gctgctaaac
     1741 caaatgatgc tagaatcaag atacctacta ctaatttttt catctcttct ctcctaatgt
     1801 tagttttaga aataaagaca gaatctgcgg ccttcaatct cacaaatccg tatgtccatt
     1861 tcgtataatt catccaatac atcttttttt atcatttctt gggtcgttcc ttgcgtaaat
     1921 aactgtccat ctttcattgc aacaatttcg tctgcataac ttgcagcaaa gttgatatca
     1981 tgaagaacaa taacaattgt tttcccgatt tcttgtacta aattttttaa aatctgcatg
     2041 atttgaaccg caaaattcat atctagattg ttcaaaggtt catccagtaa aatataatcc
     2101 gtgtcttgcg ctagcaccat tgcaatatac gcacgttgga gttgaccgcc tgaaagagtg
     2161 tcaatcgatt gatccgctat ttcttctaac ccaaggtgtt ccagtgattc ctgaacgatt
     2221 tcctcgtctt ttgtcgtcaa ttttcctttc gtataaggaa atcgtccaaa ttctactaat
     2281 tctttcacgg tgatttggac atttatttca ttcgattgtc gtaggatcga taattttttg
     2341 gctaattcat tggatttcca agcctttact tcgttatggt ctaaatagat ttcacctgta
     2401 tcttttggta tcaaacgact gatcatcgac aacaccgttg actttccagc accatttgga
     2461 ccgataaaag cagtcaactt cttttcagga atcgttaact gtacatcttt aaccactgat
     2521 tttccatggt acagtttatt gaccttttgt aaatcaatca taggatactc ttcctttcgc
     2581 gaatcaattt tgtgacaaaa taaattcctc cgacaaattc aacgacgaca ctcactgttg
     2641 tattccagcc gaaaatctgc tctactgcga gctgtcctcc tgtcagaaac agcatagcta
     2701 ccagaaagct tccgataaat agctgaccat gacgataagt agaaaagaca cgataactga
     2761 tatttgcgac aataaaccct aaaaaagtaa ctggacccac aagagccgtt gatgtccctg
     2821 tcaaaagact gacacaacat aaaatcaaaa attcaaaacg atctgtgtct atcccgaggt
     2881 ttactgcttg ttcatttccg agatggaaaa cgtctagcac atgtcgatat cgaaataaca
     2941 ggtaccagca gccgataatg atcaaagaag caggcaaaag atactgactc tggatattgc
     3001 caaagcttgc aaataatctg ccttgaagca aatcatattc attcggatcc atgatgactt
     3061 gtaaaaaggt actgacacta ccaaaaagcg tacctaaaat catccctgac atcagtaata
     3121 aaaaaagatt cgctctcatt tttttcaaaa gaaagaaaaa taacaataga ctcagcccga
     3181 ccatcagccc aacgttcaat aagaaaaaaa ctgtacctgt ctgctgaagc atcgtcactc
     3241 ctccgataaa gaagaaaagg accgtttgga caaggacata taacgactca agtcccaata
     3301 ctgaaggagt caaaaactgg ttatgcgtaa ttgtctgaaa gctgattgtg gcactgctga
     3361 cagctagcga gacaaggata aatgcaaaaa ttttcttact cctcaatgca catgcaaaat
     3421 gccagtttcc atatgtatgg atcgtcaagt acattcctgt aacaaataaa acaagaacaa
     3481 gcataccaat aaaaatagat ggcttttttt taagcatatc gtcgtcccct tatcagaaga
     3541 taaaggaaga tagccccacc gatgattcca acgatcacac tgactggtat ttcataagga
     3601 aaaatcaaca cgcgagcgac aagatcgcaa aatactaaga acaaactacc tgctaaagca
     3661 gttacgccaa ttgttttgtg cacttgatct ccatatattc tagagacaag attcggaatg
     3721 atcactccga taaaaggaat gcttcctacc atgatcaaca tgactgcact agccaatgat
     3781 actaagccaa tgcctaaaaa ctgcatcttc tggtaatcta ttcccagatt tactgcaaac
     3841 gattcgccca gaccaatgat cgtaaatcgg taagcaaata gccaaaccaa gagcaacaat
     3901 ggaacaacag catacaataa ctcataattt cctcgtatca cagtcgcaaa attcccttga
     3961 agccatgaag tcatattttg taccaactgg aattgataag caaaaaaagt agcaactgaa
     4021 ccaatgatat tccctaacat gactccaatc aacggaagca tcaattgatt tttctggagg
     4081 aacaatcgcg taagggataa aaaaagcaat gttcctgcaa aagcaaagca aaatgctgtc
     4141 aaggatcgga caatcaagga tgcaccaggt aggaaaatca tagccactaa aatacctaaa
     4201 cgcgcactat ccatcgtgcc cgcagtcgtt ggtgaaacaa atttattttg ggtcaaatgt
     4261 tgcatgatca acccacaaat actactggtc gctcccacaa ggatcaaaca aatcgttcgt
     4321 ggcaaacgag tcactagcaa gatttgtaag ctttgcccat ctaactggag cagttctgac
     4381 aattgtacat tcgatactcc gatgaacaat gaaatactac ttaaaataac taataatgct
     4441 actagtcgtc cgtagcgcat ccaatccacc tttctaattg agaatgattt tcattcttat
     4501 tttaagtgaa tcgttgaaca aaagcaaccg ctttttcata tgttttaggt attattggga
     4561 atatgctata atcgtaagaa agacaaagag aagaaggagg gtatttttta tggcacaaga
     4621 tgatgtaaaa agccatttgg ataagggact ttatggtaca cctttagtga accctgaaga
     4681 acagcataaa tatttaggga cattcaggga acgctgctat cttagtatga ctgttgctga
     4741 aatgatccaa ccaaaaaaca aagaaaactt tttaaaagaa ctcaaaaaac atccagatgc
     4801 ttccatactc ttgaatgggg ctctacccct ttctgtccaa aaccaatata tccagctagc
     4861 aacgaaaaac aatagccgtt tcactgtagt caacgattac gtcactgcaa atcctgagga
     4921 attcggattg ctcttaacag caaaagaagc agtaaatgaa cctgtgattg atatcgaaaa
     4981 aaaataccca gaagaaaact cttcgccagc tgaaaaagaa aaaccaaaaa agaaaaaaag
     5041 cttctgggat cgtttatttt aaaacgaaaa aacacataaa tttttacatg caaaaaaagc
     5101 ttttgatcag attgacatca aataggacaa tctgtcaaaa gctttttctt ttaaaatact
     5161 tcaggatata acaatttcaa tacattcatc gtcaatcttc tgccttttcc tgcaaaagga
     5221 taaacatgca tatgcatggc tggattgaaa tttgcttcga tgatcccata tgctttttta
     5281 tcagttgtag gatcgatttc tttatctggt ataatcaaat cgataccact aatcttagct
     5341 cctagtgctt ctaccgcaga aacggcgatt tttttgtaag cttcagaaaa ttcatcagtc
     5401 atatcgatcg aatcaccacc tgtactgata tttgagttct cccttagata aacaatttga
     5461 ttggcttggg gaactgattc gatcgtcaac ccttgttctt tcaacatcaa ttgttctaat
     5521 tcacctaatt ggatcaattc taaaggtgca cgatgattcg ttccacgcaa agggtcacta
     5581 tttttttctt caacaagttc tttcactgtt cggatactgt caccaataac attagcaggg
     5641 actcgcaaca tgatggcttg gacttctccg tcgatcacaa agaaacgata ttccgttccc
     5701 ggcataaatt cttctactaa aaccgaactg tcttcacgaa aagcaatggc taaacctgct
     5761 tgataatctt ccagactagc tccttccttg aaaatcgtga tacctaaccc gtaattggtt
     5821 gatttaggtt tgatcacaaa tgcctgctcg gcaaatctcg gataagcttt taccgcttct
     5881 tccatggatg aaaattctgc gcctcctggt acccggaacc cagcttcttt taagactttt
     5941 ttcgttactg ttttgttttc catgataagt gggacgatat agctgtcctt acttgtcatg
     6001 tttgcatttt tcacatattc tacatggtct tggaattgca gacgcaaaaa ttgatccgac
     6061 tcatctaata ctttgacttg gacacctttt tggatggcat cgaacataaa tatctgagta
     6121 gaaagttcca tttcgcgaaa accggccaac tgatagggac gttcatggct ttctttataa
     6181 tattgatgtc ccaatgccac agcaacttct tgctgactcg atagctgtgc ttcttgatag
     6241 agtttcgctg ctaacgtttg ttcaggatga tccatttgag tcaatgcttc ctctactaaa
     6301 taaagagaat ccaaccaatc caattcaacc agcatttgct tcattccttc aagaatttct
     6361 ctaccttctt gatgaaattc tgtttgatct gatggttgtt ctagtgctac tttgttattt
     6421 cgagtcgtac cttctgctac ccattggtca cagtcttctt tttcttctgt ccataacatg
     6481 tacatcagga ataattgtaa gaaccgaact tgctctggat tgatacccaa tcttgcataa
     6541 ggattcaaat cgatattccg caattcaata taacgaacac ctgttgttgc taaatctgcg
     6601 actttctttc cgcctcggaa acgaagcggt gtataaaatt ctttctcctc cgaaagtttc
     6661 ccttcttcga tcattcgctc gatatctgct aaatactgtt tcatagaagc ataggaaact
     6721 ttcacatttg gatgattcgt atagcccagc gcactgttgc gaatactgcg aacaggttct
     6781 tgcggatgtg attcatctaa aaagtagttc ttctcactca ttggtgaagc accgaataaa
     6841 taagtgatca tccagcgata gcgcataaag tttctcgctg ttttcaaata aagttctgtt
     6901 ttgaattcgg aaaaatcttg aaattcttcc tgatggctga acaatgttct tagcaactca
     6961 tcgccaaatt caaaattgaa atgaataccg cttaccatct gttttcgctt cccgtatttt
     7021 tttgctaaat aacgtcgata caagacatct tcgaaatttt ttaattttgc aataatgatc
     7081 tcttcgtctt tttccggtaa ggcaggtggc atacttaatg gccagatcat ctcttctttc
     7141 ggtatagaac gagcagtcac atcataaaca gcagcgagat actgaaataa ttcgggaata
     7201 gaatcggtaa caggggtgat catctctgtt tgtgtttcgc taaaatctgt ttggatatag
     7261 gggtgatagg atcgatcgcc aaagattgct ggatgatcgg tttttgctag atttcctgca
     7321 agatcaaccc gctgtccttc ccgttctata ccaaatcgag cttggtcgat aaaagggcgc
     7381 gcattgacat gcaataataa ttgcttaaaa ttcatcatta agtgacctcc aattcatatg
     7441 aatctaatta taatcaaaaa gtctaagaaa aagaacgaaa ttgtttgaga accgcttaca
     7501 aataagtata aaaatgaagg catcaaaaac acagctatgt taaaaacaat cattcaaaca
     7561 aggagctgca acttttgtca cagctcctgc tttttagaca tgggttattc ttcttttagt
     7621 aatcctttga acaatccaac gacaaaatca tttggatcaa acggctccaa gtcatcgatt
     7681 ccttcaccaa gaccgaccaa tttcactggt aaatgcaatt cattacggat agcaagtacg
     7741 ataccgccct ttgctgtacc atctaatttt gtcaaaacaa gaccggtcac atctgttgtt
     7801 tctttgaatt gttttgcttg aaccatcgcg ttttgaccag tggttgcatc taatacaaga
     7861 agtgtttctt ggggtgcttc tggtaattcc cgctggatta ctcgttttat tttttctaat
     7921 tcgttcatca agttcacttt attttgcagt cggcctgcag tatcaactag taaaacatct
     7981 gcctgctctg tctttgctct ttccaaagca tcgaatacga cagctgctgg atcgcctcct
     8041 gcattgccac gaacaacttc aacaccagcg cgttcgcccc agacaactaa ctggtcgatt
     8101 gctccagcgc ggaaggtatc tgctgctgcc atcaatactt ttttaccttc gtttttgaac
     8161 tgatgggcaa gtttaccaat acttgttgtt ttccctacac cattaacacc gacaaacaaa
     8221 ataactgtta gtccgtcttc ttggatattt agttcattta cttcattgat tccttccgct
     8281 tcatagagat ccacaagttt ctcgatgatc gcattttgga cttctgccga ttttttcgca
     8341 tttctgagtt tcacttcttg acgtaatgct tcggtgattc gtatcgctgt ttcaaaacct
     8401 acatctgcac cgataagtgt ttcttctaat tcttcaaaaa agtcttcatc gactgttcga
     8461 aaattggcaa acaactcatt catccgttca ccaaatgttt tacgcgtctt ttctaaaccc
     8521 ttgtcgtact tctcctgtac ttcaacttct tctgttttct cttcgccagt aaaagcacgc
     8581 ttgattttat caaaaaatcc catttgactc cccctactct aatacaaatt tttggatcac
     8641 tttggctacg ccattttctt cattgctggc tgtcacgaaa tctgctgctt ctttgacgaa
     8701 aggcacagca ttctccatcg ctacgcctag tccagcatat tggatcatcg gtaaatcatt
     8761 ttcctcatca ccgatcgcca tgatttcttc ttgtttcaaa ccaagatctt ttgccaataa
     8821 agaaatacca taagcttttg taacaccttt tggcataaat tccaaaagca tacttcttgt
     8881 tttgatgatc tcatacattt catggaattc tgctggtatt tctttgattt taggatctaa
     8941 ttcttcttgg tcataagcga ttactgcctt attaagcaca aattcatctg taatatcgct
     9001 tatatccgct ggttggaatt gcagcagctt attcaacaca ttgtacaagg attgcttcct
     9061 tggggcacta ggcagctgta aaaccacatt gtcagacaaa acatctagtg gcagatccaa
     9121 ttgctgagcc agtttgtata agcgttggat atctgatact tccatcactt tcttttccat
     9181 gatttcacca gtatcatttt tttgtaccaa accgccgttg aaagtgatgc tgtagtcacc
     9241 ttcatctacc agtcctaatt cttgcagata atgcgccatc gcagctaagg ggcgtcctgt
     9301 acatagaacg atcttgaccc cttgctgttt tgcttgtgct aatgcttgtt tattctcatc
     9361 tgaaatcagc ttttgttcat ttaataatgt accgtccaaa tcgattgcta ctaatttgat
     9421 cattttcgtt cctacacttt cgtttcgttg attttcgcct cttcattgat atcttccatc
     9481 cgtacagaaa cgatttttga tacaccggat tcctgcatcg tcactccgta cagtacatct
     9541 gctgcgacca tcgttccttt gcggtgtgtg actacgataa attgtgtgtc atcttggaaa
     9601 tcgctcaagt aacgaccaaa acgtttcacg ttggcttcat ctaacgctgc ttctacctca
     9661 tctaagatac aaaacggaac aggacagaca cggataatgg aaaagagcaa cgcgatggct
     9721 gtaagtgctc gttctcctcc agaaagcaaa cttagacttt gcagtttttt gccaggaggt
     9781 tgtacttcaa tctcaatacc tgttttcagc aaatcagttg gttccgtcag tactaattca
     9841 gctttaccgc cgccaaacat atttggaaag acaattttga attcttgacg gatagcttca
     9901 aatacttctt tgaatcttgt ccgcacttca tcatccatct catccatcgt ttcaaacaat
     9961 tggtttttcg ctgctaacag atcatctcgc tgtgttgcta agaatgtatg tctttcactg
    10021 acttgttcgt attgttcgat tgaatttaag tttactggtc ccagtttttc aatctgttct
    10081 tttaaggatg aaacctttgt tctactgtct tcgatatcgg ttgtttcttg atagtcttgg
    10141 gaagctttct caaatgtcag ctgatattct gactgcagat aggtcaaatg attatctaaa
    10201 atcatttcag ctcggtcttt ttggacttct aatttggatt gttccgacag tcgtgctttt
    10261 tgctcacgat tacgctctgc caagactgct tcaagcttat cgatctcctt ttgccttcta
    10321 tctcgctgct ctttggcttt tgccaactcg gcttttaatg tttctcgctg agcagataat
    10381 tcgttaattt gtttttccaa actttcttct gtgacttcat gatcagaaaa gtctgctgtc
    10441 aatgtcgcca actgcttttc tatcgcttct tgacgttcgg ttgcctctgc tttttggact
    10501 cgggcaccgc ggagctggat ctgcagatga ttaaactgct ctttcaagac agcaagatct
    10561 gcttgttctt gtgctttttg actttgtact tgtgctcttc tggcttccat ctggtcgctt
    10621 tcttgactta acgatttgat ttcttcgtcg attttttgtc gttgcgattc aagatctgtt
    10681 tgtttgtctt tcaattcgtt cgtttgcttt tcgtaatctt cgataaactg ctgcagttca
    10741 cgtgtctcaa aagttgagat ttgcttttct ttttcaaaac gttcaagttc atttatgatg
    10801 ttttgtagct gatttgtcgc ttcttgttct tcaaaacgta attgttcgcc tcgtgtacgc
    10861 aaaacttctt gttcttcggc taaacgagct gtttcttgtt gcagctcctg aacttttttt
    10921 tcttgtgctt ggagttgttt atctgcttct tcaaattcac tagtcaactg tttcaattct
    10981 tgattttgta caaacaaact gccttggttt cctcgtttat tcgctccacc tgtcatggat
    11041 cctccggcat tcatcacatc accttctaag gaaaccactc gatattgata gcggatcgtt
    11101 tgcgcgattg cattggcact agttaagtct ttggctaaaa ggatcgttcc tagcaggttt
    11161 tgaaccacag tttggatttg atcgggataa ctgacttgtt cactggcaat ccctataaac
    11221 ccttctacag ctgctgcttg tgtcaatata tgagccggta attgtcttgg tttgattgtc
    11281 gtcagtggaa ggaatgttgc tcttcctcct ctttgctgtt tcaaatacgt gatggcttgc
    11341 cgagcatctt tttcattttc aacgatgaca tgctgggctg ccccacctaa agctgcttcg
    11401 atagctaacg tgaaatctgc aggaacatcg atcagttcag ccactgctcc gacaataccc
    11461 gaaagctgct gtttatgctg caagaccaat cgaacccctt ggtaaaaacc aaaatagttt
    11521 tcttggattt cttgaaggct tttcttacga gcacgtagct gctggacttg attcattaat
    11581 tgatacattt taggctgttc ttttgctaat gcttcttgga actttttccc gttttgttgg
    11641 atcatttcta acttctcttt tgtttcagtt aaagatgatt ttagctgcgc ctgcttttgt
    11701 gtcaattctt ctttttgtaa gatcaatcgg tctactgatg cttctacttc cgattgcttg
    11761 gctaacgtct gcttgctttt tgctgtttct tgtatatatt gacgttctag atacttcagt
    11821 tcgtttccta cagctgcttg ttcttgcatc aaatcaacat attgatctct taattctgcc
    11881 aataattctt tcgttgattt ttggtatttt tctaattctt gctgtgtttt tatgagattt
    11941 gcttcagctt tttggatctc tgtttctttt tctgctgctg ctttcatcaa gctttcttga
    12001 agcttttcaa aatgtttaac ctttttttgt gcttctgcta atgaagtttg atattcttgc
    12061 gagctttttt gtgtatgctt tgtccgctcc tgcaaaacat ctttttgtcc ttctgtctgc
    12121 ttcagttttt ccgaaagatc taataatact tgctgatttt tttcgatcag acgatcggct
    12181 tgcgcatttt ctttacgctg cttcgccaaa atggattctt gttcttggat cgactcagat
    12241 agtttgccta attctagatt gaatttcgca agctgtgctt gtttgttgtc ccaatctttt
    12301 tttgctgtct tgatttcagc aaccatcaaa gagacatcgg tttgagtcag tgtttctttt
    12361 agccgtaaaa actcctttgc tgcctcactc tgggcggcca aaggagttaa ctgttcttcc
    12421 aattcgtgga tgatgtcttg gacgcggctg aggttgtctt ctgtttcaaa aagcttctgt
    12481 tctgctttct ttttccgctg cttgtatttc aagacaccag ctgcttcttc aaagatccca
    12541 cgacggtctt ccggtttact actgaaaatc gcttctactt ttccttgaga aatgattgag
    12601 aacgattctt ttcctaatcc agaatctaag aacaattctt ggatatcttt taatctgcag
    12661 ctttgtttat tgatgaaaaa ctcgctttcc ccagtccgtc gataacggcg ggttacactg
    12721 atctcattgt actccaatgg cagataatga tcactattgt ctaaaatcac tgtgacttct
    12781 gcaatattca gctgcttacg ggtatcggaa ccggcaaaga tgatatccgg catttttccg
    12841 cctcgcagac ttttagcaga ttgttctcct aatacccagc ggatagcctc tgtaatattg
    12901 ctttttccgc tgccatttgg tccaaccact gctgtgacgc tattttcaaa atcaatgact
    12961 gtcttgtctg caaatgattt aaaaccggct atttcaattc gtttcaaata caaagctttc
    13021 cctcacttac ttttacagtg ctgccaatgc attttccgcc gcagcttgtt ctgctaattt
    13081 tttcgatttc ccttgtccag tgccaatcaa ttgatcatct acataaactt cgatccaaaa
    13141 tactcgttca tgagctggac cttcttcatt gatcaatcgg tattcgattg atacatcacc
    13201 tgatttttgc aagacttctt gtagttttgt tttatgatcc atctcatgtg aaaaagcacc
    13261 tgctttgact ttaggaaaaa tcactttttc gatgaatgca tgggtcgtgt cgaatccctg
    13321 gtcaagatat aacgcgccta aaaaagcttc gaataggtcg caaagcaatg ctggtcgcgt
    13381 acgtcctcct gaattctctt ctcccttgcc caacaaaaca tattgatcaa agtgacattc
    13441 tttggcaaat ttcgacaagc tgtcttcgcg aacgatcgca gctcgtgttt ttgtcaattt
    13501 tccttctggc aaatgaggat ataaacggaa taaatactga gaaaccatca gttctaaaac
    13561 ggcatctcct aaaaattcaa gtcgctcatt atccgataat tgcagattgc gatgctcatt
    13621 cacataggat gaatgggtaa aagcttgttc aagcaaattt agatcgtgaa aaacgatgtt
    13681 atagttttct tttagttctt ttgtcagctg gttgtccatt ttccacattc cttttatgga
    13741 tattttttcg atacttcctt attatactgg ttttttgtca aatttgaaat ggttcggtca
    13801 aaaggtaagt aaagctttaa taatcctagt gattgacgag aagttgtgaa aaattcgttt
    13861 agtttcgagt atgaagaaaa aattttgtga aaatggcttt ccatattttt gcataaattt
    13921 gacttaatac cgagaaactg gactttgaac accgtttatt ggagaagtca tgaaatcagc
    13981 gccttgacct gaatattaga gaaataaaca gaaaaatatc aaaaaaccga aaaaggacat
    14041 cgcccttttt cggtcatttt tagtgattat gaacgtgaat ctgctgtaac agaaacattt
    14101 gcccatgggt ttggtacatc ataagaccaa tcccagtctt tgacacggtc gttgactggc
    14161 aatacttcat tacggaacaa cgttggaatc gcaaatgctt cttcaaatgc atattgttgc
    14221 catttttgat atgcttcttt ttggtactct tcatcaaatg ctttgcttga actgatatcg
    14281 ttgatcaatt ttgtattttc ttctgattca taacgagtgt agttgaacgc agcatttggt
    14341 ccccatagtc cacttggatt tggatcagtt cctgtattcc aagcagcttg gtaaacatca
    14401 atttcaggat catcgttttc taatttatca tagaaagaat tgaattcgat cagacgacct
    14461 gttgtgtatt ggacatccaa accaatttct ttccattgtt ggatatagta atctgccaat
    14521 ggttgcgctg tttccccacc ggacatcgaa gcaaagttga ttgttagttt atttccatct
    14581 ttgtcttctc ttaaaccatc gtcatccaca tctttgtagc cagcatcatc taatagtttt
    14641 ttcgctttgt ctagatcttg tgtgaatcct ttcatctcat catcatggta tgactggaat
    14701 actggaggaa tcaatgaagt cgcattgctt ctcaaacctg catagaaacg ttcacctact
    14761 gcattattat ctaatgcata gcccattgct tgacgtaatg atttatcagc catttttgaa
    14821 tctggattgt attccacact ctttgtatct gcattccatt tacctaactt gaatcctaga
    14881 taagtataag aagtttgttc acggcctaag tttgtatagc cagcaatttc tttataggta
    14941 tcgtaagtat ctgttggcat ttggaaaatc atatcatata atttagagtt caatgcttca
    15001 gttgcacttg ccatcggtac agatttcatc gtgatctttt tcaatttagg cgtaccattc
    15061 cagtagtgct cgtttggcaa gtattctact gattctcctg caacgatatt actcatgtaa
    15121 taagggccaa aagtcactgg atttttacgt acttgatcgc ttgattccat atctttgatt
    15181 gctacacctt ctaacgtatg ttttggtgct gcatatgacc agataccacc acccgattga
    15241 agcatgcttg ggtttacttc tttatattcg atttcaactg ttttgtcgtc tatttttttg
    15301 attccggaga ttgtgtcggc acttccatca tgatattctt ccatacctac gatgttacgg
    15361 aaagtgtcgt cataacggat accagtgtaa tctttattcc caatgatttc gtaagggaaa
    15421 atcacatcgt ccgccgttac atcttcacca tctgaccatt tgacgttgtc ttttactttg
    15481 attgtcgctt ttttcgtatc ttcatctaga tcaagcgttg cagctccgtc gtctgtgatt
    15541 ctgaaatcgt catcgtttgc aaatagcggt tcatgagaag gagccataaa agctgcatca
    15601 tatgaatctt ggtaaaactc ccactggaac aatcctttaa actgactgtc cgttgcgacc
    15661 gcagcttcta attcgccgtc ttcgattgca tcatcattat tttttgttgc aattggaaaa
    15721 gttaattcct ctttgttatt gccgttgcct ccagagttgt ttccagaggt atctgtacct
    15781 ccgcccccgc atgctgcaag aacgacagca gacatcagcg ctgcaaatcc aaaaatcgtt
    15841 ttcttcattc ctatttcccc cttcgcttct atactagcct aaccgttggc gcgcatctgc
    15901 agaacgcttg aatgcttgtc caacataatt gatactcaac atcaaaacta aaataaggat
    15961 tgatgcgggt aaccagatcc attgccgatt cactaagact tctccgttac ttgcataacc
    16021 gatcaatgta cctaaactag gtacatttgc cggcaagccg aaacctaaga aagtcaaagt
    16081 tgtctcgata ccgatgtttg ccgcaaagtt catcgtcaaa ttagtaatga ttaatgaact
    16141 tagattcggc atgatttcgc ggaacatgat tttaaaatca ttggttccca ttgtttttga
    16201 ggcactgaca taatctcttc ttgcttcaga taatgtcttg cttcggaata atcgggcttt
    16261 agctacccaa taaaatgcac tcatgatgaa tataaaggac cagacattgt atctggaaat
    16321 aatcgatacg aagacgataa tgatcagcat gatcggtaga atcatgataa aatcaacgat
    16381 ccgcatcaag atgttgtcaa tgatccctcc gtagtagcca gagatgatcc ctaatccaac
    16441 cccgatgatc gaagtaagga tcgtgatcgc aaatccgatc gtaacagagt ttctagcacc
    16501 tatgatcaat tgtcctaata catcacgtcc gccttcatct gctcccagaa tgaacttttg
    16561 tccttgtgtc gaaactgttc ctggtgcagc gtatttgtcg aagatactaa catacatcac
    16621 tttgtcttga tcggtcagca tcgcaccgat aaagatcact aataataaaa ccactagcaa
    16681 acctaatgaa aaaatagcaa ttttatcttt tttaaattct cgagcaatca ttcgtatccc
    16741 cataggagga atactttctt gaactgctgt attgtttttt tcactcatcg atccattctc
    16801 ctttctgatt ggttttattg aatccgaata cgcgggtcaa cgatactcat gatgatatct
    16861 gaaagtaatg tccccactag cgtcgcgatt cctaaaatca atactaagga tgtgatcacg
    16921 gtatagtccc gttggccgat ggaatcaata aatagttttc cgactcccgg ataaccaaaa
    16981 atcttttcga taactacaga accagcaatc aacgaagtga tttcataccc catttgagaa
    17041 gccatcggca acgctgcatt tcggaaaata tgtcgactga atactttatt cgtcggtacc
    17101 cctttggaac gggctgttct gacaaaatcg agcgatttcg aatcgattac ttcacttcgc
    17161 agatattgga ttgtgacggc agtcgccaaa aatgcttggg taattgatgg taacagaata
    17221 tatttcaaac ggtctatcca ttgagtgata aatccacctt gcaaacctag tgtttgtgat
    17281 ccacttgttg ggaaccagcc taaacgataa ccaaaaacaa atagcatgat caagccgaag
    17341 ataaataaag gaacagcaaa actaaagaag ttgtagatta cgacaatctt atccaagatt
    17401 gaattttgat accggccagc aagcatcccc agaggcacag caatcaaata agtaaggaca
    17461 actgtcaaga tcgatagata taaagtgttg atgatccgtt cgccgatcaa gtcagcaaca
    17521 gagcgtttgt ataagaaact ttgaccaaaa tcgccttgca aagcatttcc gatccaacgg
    17581 aagtactgga cataccatgg gtcattcaag ccagctgctt gtcgcatctg ttcgatcact
    17641 gccggatcct gatttggatt gatcaaaccg gtaaatggat cccccggcat cgcttgggct
    17701 aataagaaga tcagaacact taaaataata acttgcggga tcatcaataa aacacgtcgc
    17761 agaatcgttt tccacattag cttgcacctc catctttcaa cgccactttg tgtgtagttg
    17821 tgatcgtacg caaatcgtag actcgaccag tcgcatcata gtattctttt tggttttgga
    17881 tatactcttg ttctactctt cgtcgatttt ctttgtggct ttccctattt tctacatcga
    17941 tttgcggaat agctgaaagc agacgtttcg tatagatatg tcgcgggtca ttataaatgt
    18001 cttctcttgt accgatttct acaaatcgac ctttgtacat aattgcgata ttgtcgcaca
    18061 tgtgttttac tacacctaaa tcatgtgaaa tgaataaata gctgaggccg tattcttgct
    18121 ggattcgttt catgaaattc aatacttgcg cttgaacaga tagatccaga gcagatacag
    18181 gttcatcggc tacgatcagt tttggattgg tagcaacagc acgggctact cctagacgtt
    18241 gacgttgtcc gcctgaaaat tcatgaggat atttatatag cgcatcttcc ggcatcccaa
    18301 cgatatctag cagtcctttt acctttttct tttcttcttg atcgcttaac cgttcaaaat
    18361 ttcggatggg ttcagcaatg atatccaaca ctcgcttttt aggattcaaa ctggacattg
    18421 aatcttggaa gatcatctgc acatccttgt tataacccat ttttttgcgg ttgcttcgct
    18481 tcgttacatc ttttccttca tacatgattt gtccggctgt taccttttct aatcccacaa
    18541 cggcttttcc cgtagtagat tttccagagc cagactctcc cactaaacca tatgtctttc
    18601 ctttttcgat aataaaatcc acaccatcta cagcatatac atgatccgtt actcgattga
    18661 agaatccact gcgaataggg taatgaactt tcaggtcttt gattgtgatt aattctgtca
    18721 tctacacctc tcctttttcg tctctaaagt ggaaatgctt atagcaggag caacgtacca
    18781 agtggttcgg tgcgacttca tgaaggatag gctcttcttc atgatcgctt gctggtatcc
    18841 atggaatacg tggtgcaaac cgacaacctt tacgaggcat gtttttcaga gaaggaacga
    18901 caccttcgat cacatggagt tctgcatcat gatttccttc ttgtggtata gagttcagta
    18961 aagagcgtgt ataaggatgc ttaggatgat caaacagttc ttttacacct gctacttcaa
    19021 cgaactgtcc gccatacatc actgccactc gatcagccat ttctgctacg actcctaagt
    19081 catgagtgat caagatgatc cctgtttttg tttcttcctg aaggtctttc agtaaatcaa
    19141 gaatctgtgc ttggatggtt acatctaggg ctgtcgtcgg ttcatctgca atgacgattg
    19201 gaggtttgca ggcgattgcg attgcgatga tgacacgttg tctcataccg cctgatagtt
    19261 catggggata ttggcgtcca actctcgcag gattaggaat ccctacttgt tctagcaatt
    19321 ctagtgcacg agcttgacgc tgttctgcat tcatctttgt gtgataggaa agtccttctt
    19381 tgatctggtc ttcgattctc atgagaggat ttaatgcaga caacggatct tggaaaatca
    19441 ttccgatatc atttccgcgg attttattat agagcgtttc gttcaggtcg attaaattca
    19501 gatcgttata taaaatctca cctgtaattt ttgtgttatt aggatcaagt aatcccataa
    19561 tcgtagtagc caaggtactt ttcccgcacc cagattcccc aacgattgct aaaatctcgt
    19621 ttttgtctaa agtaaatgaa acgtcatcta ctgcatcgta atagtcatct ttgagtcgga
    19681 atcctgtatg taggttctga acttctaata attggttatc ggacaatcga atacccctct
    19741 ctgcttccta aatggaagtt tttcttaata aaaaaggaca ttacacagaa taaagcgttt
    19801 tataacaaag gttattctta tctttgtgta atgaattatt aataattata tagaaaatcg
    19861 ctttactttg caacataatt tctgtttatc gccagaatta tcagaaaaat gacttttacg
    19921 tgtcaaaaag attaaaaaaa gaaggataaa aagctgtatg cagcttttta tccttctttg
    19981 cttttatttg aaattattta agatggctgc tgatataatc tactgcgcca ccgactgttt
    20041 caatttgttc agcgtcttca tctgaaattt ccgtaccgaa ttcatcttca agctctaaaa
    20101 cgaattccat aatactaatt gaatcagctt ttaaatcatc tttgatgttc aattcatccg
    20161 tcactttatc ggtatctatc tcaaaatgat ttgaaataat tttcgctact ttgttaaata
    20221 cttcttcgcg agtcaacttt ttcacctcca agaatcatac acttgtcaat tacctacacc
    20281 atggctaatt ttactggcat ttttcaggaa tgtccacctt tttttcaatg gaacggattg
    20341 cttcagatat ccaaatacta ttcttcgctt ttttcaaatt gttcgactaa ttgtccaact
    20401 acatctgtct caagcattgt gtggatttgg cggatcgtat agcgaacagc atcggggcct
    20461 gttgctccat gagttttaat gactggtgct ttcaagccaa acaaaacggc accgccatgt
    20521 ttggaataat ccatttctgc tttcaaagaa cgtaagccgt cttttaaaag catagcgccc
    20581 atttttcctt tgatcccttc atttagaata gcagatttta atagattcat catattcatt
    20641 gctgttcctt caatagattt caaaacagcg ttgcctgtaa atccatctgt gaccactaca
    20701 tcagccacac cattgagtag ctcacgagct tctacgtttc caataaaatt caagcttgtt
    20761 tcattctgaa ggagttcata ggcttttttc gtcacttcac taccttttgt tgcttctgtt
    20821 ccgttgttta agagtgcgac acgaggacgt ccgatacctc ggactttacg tgcataaaaa
    20881 gaacctaaaa taccgtattg caacaaatgt tctggtttgt tttctgcgtt agcgccaaga
    20941 tccagcatat cgaaaccggc accttctttc cctactactg gcaaggtaga catcaagcca
    21001 gggcgttcga tatttttgat acgtcctacg atgaacaacc ctgctgctag tagcgcgcct
    21061 gtattccctg ctgaaaatac agcatctgct tcaccgtttt tcactgcttg tgcagcaagg
    21121 accattgatg cagtcttttt tcgtcgaatt gcttttactg gctcatcatc actattgatt
    21181 ttttcgtctg tatggataat cgtgatgttt ttttcatttg ttaagtattt cttgatttct
    21241 gcttcttttc cgtaaagtaa gaattctact tctggaaaat cttgctgcgc taaagccacg
    21301 ccttctacaa ttgcttgagg tgcgtgatct ccgcccattg catctacggc aattttcatt
    21361 gtttccactc ctttttccgt catcagtata aagtatagca cagtctgcta atcgaaataa
    21421 cgattatcct gattttctat ttggaggctt tgcgctaaag gctgatactc aggaagcatc
    21481 tgccaatcct ttatctgcca aagggctgca gcctcttctc tggctacctc caaaacattt
    21541 ccatccgtca ccaagtcagc aatcgcaaat tgaggcagac cagattgacg gaagccaaat
    21601 acttcaccag gaccacgtaa ttccagatct ttttcgctta gtacaaaacc attggtggtc
    21661 tctgtcatga ttttcatccg ttccacacct agttcatttt taggattagc aactaagata
    21721 cagtaggaag catcacttcc gcgtccaaca cgtccacgaa gttgatgcag ctgtgccaat
    21781 ccaaatcgat ccgcatccat gatcagcatg acggtcgcgt tcggcacgtt tacccctact
    21841 tcaattacag tagtcgaaac taatatctgc atctggttgt ctttgaaggc ttccatgatt
    21901 acttcttttt cctgattctt cattttacca tgtaacaagc caacttcata ttttggtgca
    21961 aatagttcac gaagtttttc atagatttcc actgcatttt ttacatctaa tgcttctgat
    22021 tcttcaatca gcggacagat gacatacatt tgatgtcctc ttgccagttc ttttttcgtc
    22081 caatccagta cactgtccaa ttgaggtgtt cttacccagc gtgtttcgat cgggatacgt
    22141 ccagctggaa gttcatcaat gatagataca tccatctcac catatgctgt aatagctaat
    22201 gttctaggaa tcggagtcgc tgtcataaat aagacatctg gtcgccagcc tttttcacga
    22261 agtactttcc gctggttcac gccaaaacgg tgctgctcat ccgtaataac tagacctaaa
    22321 ttctgaaatt cgactccatc ttggatcaat gcatgtgtgc cgatcacgat gttaatttcc
    22381 ccttgctcta gtttttcaag gagctcacga cgttcttttg ctttcgttga ccccgtaagc
    22441 aatgcgatgg ttacttcatt gggatcaaac agctgttgca agctttccat atgttgttgt
    22501 gccaagattt ctgtaggcac catcaacgca ccttggaaac ctgctgtaac ggtagcgtat
    22561 aacgcaatcg cggcaaccac tgtttttccg ctacctacat ctccctgcaa aagtcgctgc
    22621 atatgctgcg gactgcgaag atcccgacag atttcattcg ttacacgttt ttgtgcattt
    22681 gtcagttcaa aaggtagctt ttgagtaaat tctttcaatt tttggacatc ataaaggatc
    22741 tccaaaccat tcgtttctgc tttttctgct tttttcaatc cttgaagacg catttgaaat
    22801 aaaaagaact cttcaaaaac gacacgtcgt ttggcttgat ggttttcttc gtggtctttt
    22861 ggaaaatgca tacttcttac agcagaagct cggtcaagca gtcgatattt ctccacaagg
    22921 ttgtttggca gattttcttc aatcaatgtg ccgtattctt gaaacccttt tttgattaga
    22981 tcaactaatg tcgtttgacg aattgatttg ttgacgtgat atatcggcga aaagtcatcc
    23041 attgtttgag aacctaaaat cttcatcccg ttcaatgctt tacgctttgc atcccattta
    23101 ccgtatacgg cgatttcctc cgataaaatg actttttctt ttagataagg ttgattaaaa
    23161 aaagaaacgt tgaacacatc atgttcttgc atcatacgaa attgcaatcg gcttttttta
    23221 taaccaaatc gattcatcac aggaggcgag actacgattc ctttcaaagt aaccttttct
    23281 tgatcttgga tctcgtttag atttctttcc tgaatatctt cgtagcggaa aggataataa
    23341 gtcagtaagt cttcaatcgt ttggatgccc aagctggcaa gactagctgc tcttttttct
    23401 ccgactcctg ccagcatagt gattggatca tctaaagaac gcataaattt ttcctccctc
    23461 ccttaacaaa aaaaggactt ggtcagcgat catacctgat cactaaccga aggcctttta
    23521 tgaatgaata ctgtgttaga aagatattct gacacagaaa ttattcagca gaaaatagat
    23581 aaggatagac aggctgatct ccttggtgga tctcgatttc caaatcagga tgtttttctg
    23641 ttagtttctc agcaaattca tttgcttgtt caactgttcc ttcatcacct gccaagatcg
    23701 ttacgatctc tgtgtcctca ttgatcattt gttctagtgt acttaacgct gttgctgtga
    23761 tatctgggtt agagatcagg atttttccat cgatcatgcc caaaaagtct ccttctttga
    23821 tctctacacc gtcaattgag gtatctctga tcgcgtgagt gacttgaccg ctcacaacgc
    23881 tagacaacat ttctgtcatc gtttctttgt tttcttctaa agaagcttga tcattgaatg
    23941 aaagcatagc tgtcaatcct tgggaaatcg ttcttgaagg aacaactgct actgggatat
    24001 ctgctacttc tgctgcttga tcagctgcca tgaagatgtt cttattgttt ggcaagacaa
    24061 tcactttatc tgcgtttact tcttgaatcg ctttaacaat gtcttccgta cttggattca
    24121 ttgtttgccc accactgata acataattag cgcctaaact ttcaaacagc tcttggacgc
    24181 ctttaccagc agcgatcgct acgataccat acgggatacg tggtgtttct tttttcgcaa
    24241 actcgttcac ttcttcatcg tgttccaaaa tcgtctcatg ctgcaagcgc atgttgtcga
    24301 ctttgatttt gactaatgaa ccgaattttt gtccataatt caagacttct cctgggtttt
    24361 ctgtatgcac gtggactttg atgatctcgt catcattgac cacaagtaaa gaatctccta
    24421 taccatctaa atagttacgg aattcttcgt aatcgaatgt actatcgact gtaggtcctt
    24481 ctccgatttt taccatgatt tctgtacagt aaccaaaatg gatatcttct gtcgccattt
    24541 gaccttggac actgcgatga tgttctgcat tgaccatatc atccatttct gctggagaag
    24601 gttcatatgt ttcatccgct tggaattctc cattcaatgc acttaaaaag ccctcataaa
    24661 caaacagcag tccttgccct ccactgtcta cgacaccgac ttcttttagg actggaagca
    24721 agtctggagt tttagctaaa gcacgctttg ccccttttac aacagctgtc attacttcaa
    24781 cgacatcatc agtacttttt gctttctttt ctccagcttt cgctgcttct ctagctactg
    24841 tcaaaatcgt tccttctact ggtttcatta ctgctttata cgcagtttca actccatgag
    24901 tgaaggctgc agcaagatcg gaagcattta atgagacaac atctggaatt tgcttagaaa
    24961 atccacgaaa caattgagac aaaataacgc cggaatttcc gcgcgcaccc atcagcaatc
    25021 cttttgaaag cattgctgct aattctccta ctttttctga ggttgaatct actactgcct
    25081 tagctccact agtcatagat agattcatat ttgttcccgt atcgccatct ggcacaggga
    25141 atacatttaa tgaattgacg tattctgcat ttacttgcag acgattcgca cctgcctgga
    25201 ccatttcctg gaactggctt gcacttattt ctgttacact cacctagata atcctccttc
    25261 agatcgactg ctgagttacc agccagtctc ctgcctagtc tggcagtaca cgaacacctt
    25321 gtacaaagac attaactgaa ttggcagtta cgcctaataa tgcctctaga ttgtatttca
    25381 ctttttcttg gacgttgcgg gaaacttcag agattttcgt accatagctg ataatcgtat
    25441 aaacatctac agcaatacca ttatcttctt ggcggacaac tactcctctt gagtaatttt
    25501 ctttacgcaa aatctcagta atattatctt taatttgatt tttgctggcc attcctacaa
    25561 caccgaacac atctgtcgcg gcgccaccaa caactgttgc aattacatca ttggtaattt
    25621 caatggttcc agctgacgtt tgaattttta cagccatgaa tgagcctcct taacgggtaa
    25681 aaaactccca tttttcttct atcatatttt atcatagcgc aacttgaaat aaaaggcagt
    25741 tacccaaagt actcaaaaac cttgcaaaat ttcaggtata accttgttta atttacaatt
    25801 attcttctca attgtcaatt gtatctatga aaatgtactt gcaaatttcc attctatatg
    25861 atatgttagt ctggtatgag ctgaattatt ctattgctcc aaatcaaggc aaaggaggaa
    25921 attaccatgg caaaagtttg ttactttaca ggtcgcaaga caaaaagtgg aaacaaccgt
    25981 tcacacgcta tgaactcaac aaaacgtact gttaaaccta acttacaaaa agttcgcgtt
    26041 atggtcgacg gaaaacctaa aaaagtttgg gtgtcaactc gtgctttgaa atcaggaaaa
    26101 gttgaacgcg tttaattgaa tgatacttgg accgttcaga tagtgaacgg tttttt
//
LOCUS       DADVXE010000036        25592 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.037, whole genome shotgun sequence.
ACCESSION   DADVXE010000036 DADVXE010000000
VERSION     DADVXE010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.037"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            55..609
                     /locus_tag="KB913_001616"
     CDS             55..609
                     /locus_tag="KB913_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6819982.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(782..1255)
                     /locus_tag="KB913_001617"
     CDS             complement(782..1255)
                     /locus_tag="KB913_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6819983.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1267..1803
                     /locus_tag="KB913_001618"
     CDS             1267..1803
                     /locus_tag="KB913_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6819984.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            1843..2214
                     /locus_tag="KB913_001619"
     CDS             1843..2214
                     /locus_tag="KB913_001619"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6819985.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            2498..3769
                     /locus_tag="KB913_001620"
     CDS             2498..3769
                     /locus_tag="KB913_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBB6819986.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            4014..5039
                     /locus_tag="KB913_001621"
     CDS             4014..5039
                     /locus_tag="KB913_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6819987.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5333..6442
                     /locus_tag="KB913_001622"
     CDS             5333..6442
                     /locus_tag="KB913_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBB6819988.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            6525..7421
                     /locus_tag="KB913_001623"
                     /pseudo
     CDS             6525..7421
                     /locus_tag="KB913_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            7437..8261
                     /locus_tag="KB913_001624"
     CDS             7437..8261
                     /locus_tag="KB913_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6819989.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8293..9603
                     /locus_tag="KB913_001625"
     CDS             8293..9603
                     /locus_tag="KB913_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HBB6819990.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            9751..11010
                     /locus_tag="KB913_001626"
     CDS             9751..11010
                     /locus_tag="KB913_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6819991.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11020..11892
                     /locus_tag="KB913_001627"
     CDS             11020..11892
                     /locus_tag="KB913_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6819992.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            11904..12734
                     /locus_tag="KB913_001628"
     CDS             11904..12734
                     /locus_tag="KB913_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6819993.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            12774..14957
                     /locus_tag="KB913_001629"
     CDS             12774..14957
                     /locus_tag="KB913_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBB6819994.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15018..16238
                     /locus_tag="KB913_001630"
     CDS             15018..16238
                     /locus_tag="KB913_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HBB6819995.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16235..17695
                     /gene="gtfA"
                     /locus_tag="KB913_001631"
     CDS             16235..17695
                     /gene="gtfA"
                     /locus_tag="KB913_001631"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HBB6819996.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            17772..18878
                     /locus_tag="KB913_001632"
                     /pseudo
     CDS             17772..18878
                     /locus_tag="KB913_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19200..19409
                     /locus_tag="KB913_001633"
     CDS             19200..19409
                     /locus_tag="KB913_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBB6819997.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMASKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19402..19551
                     /locus_tag="KB913_001634"
     CDS             19402..19551
                     /locus_tag="KB913_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBB6819998.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            19705..20370
                     /locus_tag="KB913_001635"
     CDS             19705..20370
                     /locus_tag="KB913_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6819999.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(20654..21739)
                     /gene="xerS"
                     /locus_tag="KB913_001636"
     CDS             complement(20654..21739)
                     /gene="xerS"
                     /locus_tag="KB913_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBB6820000.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            22073..22306
                     /locus_tag="KB913_001637"
     CDS             22073..22306
                     /locus_tag="KB913_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HBB6820001.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            22303..22710
                     /locus_tag="KB913_001638"
     CDS             22303..22710
                     /locus_tag="KB913_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBB6820002.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(23847..24365)
                     /locus_tag="KB913_001639"
     CDS             complement(23847..24365)
                     /locus_tag="KB913_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBB6820003.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            25483..>25592
                     /locus_tag="KB913_001640"
     CDS             25483..>25592
                     /locus_tag="KB913_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6820004.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELT"
BASE COUNT         8718 a         3918 c         4780 g         8176 t
ORIGIN      
        1 gtaaaatata tacataatca ttaactcaga atatttttaa gaagggaaac aatagtgagc
       61 tataatgtac aaccgttaag gacaaatgaa gagatacaag attttcagtt ttggctaaga
      121 agaacaagta atccggaaag agatagtttt ttatttttgt ttggaatcaa taatgggtta
      181 cgtatgtcag atattatagg attaaaagtt ggagatatac gaggcaaaag taagcctatt
      241 attgttgaac ataaaacagg taagcgaaaa ccgattttta tagataattt gagagaagaa
      301 attttattat atactgaagg taaagaagaa aatgattggt tatttccgag tcggcaacaa
      361 ggtcgacata taacaaggga tcgtgtctat cagatatatg cagatatagc agaaaaatta
      421 ggacgagatg atataggaac acatacatta agaaaaactt ttgggtatca ctactacaag
      481 aaaactagag acattgctac cttaatgttt atttttaatc atagctcgca agcaattaca
      541 aaaaggtaca ttggtataac tgaagatgaa ataggagcat cacttcgtgg atttaaacta
      601 ggtgtataat ttaaaaattt ttataaacag taaagacaaa gattaaaagc tatttttatc
      661 tagaacgatt ttatttcata aagttcgcgg aataaaagct ggggttactg gtacttggta
      721 taggttcgtg ttatataaac taagtaatta aataacattt ttaggttgga aaaggatgaa
      781 attaaaaaaa gagaatcaat acggtctcaa aaacgcaaac gctgcggaat aagaaaaata
      841 ctgataactc aacgtttagc agactatcta atagggatag tctgcttttt tcgtttttga
      901 ccatactttt gaccttctgc aaacttcctt gcttttcctc tgtagaactc atgaaatctg
      961 caaaacgaat tgccgtttcc tctgtctgct ttttcgcgat atgggtgtat atatcatcca
     1021 tagtggtttt aatatctgta tgtccaagtc gaacatacac ttctttgaca gacgcaccag
     1081 attcaaagag cagactacaa tgggtatgac gaaaaccatg aagtgtgata tgttttaagt
     1141 tattctcttt aatgatgatt ttcaaattgt gatttacata gtctaaataa aggggcttat
     1201 tttcttctga tgaaaacaaa agttgttcac catcttttat aggtttgatt ctcattttta
     1261 gatattatgc ccgcacgtat tcatcacatt tctattgtga atcgctttat tcgaccgaca
     1321 tttgactttt atcataatat actcggttta aaattactaa tgaaaacaat taatcaagac
     1381 gatcatacca tgtatcacct gtttttttca gataatcacc accgtgtggg aactgaactg
     1441 actttttttg aagtacaaga agggaacaac cagttttttg gaaccaatac gattgaacga
     1501 acgatactaa aagttccttc cgaagcatca ttgcattttt gggaaatata ttttgaaaca
     1561 caaggcgttt gccattatgg aatcgaatca ttttctggac gacctatctt acgttttgaa
     1621 gggccagatg caacacgatt agctttagtt cccttacgcg aatttgaaga tattgatgat
     1681 tatttcccgt atgtcacaga ccagatccct acagagcatg ccattttagg aattgatgcc
     1741 attcaactac gcgtacaata ttccgatgcg actgaacgag agttattgtc ggtaggctgg
     1801 tagcacaaag aatacgtcag tttcttttcg ggtcatcaac gagtgacaat cttagaaaat
     1861 caagacactc agttctatca agaagttcag attattcaag atcgtgagaa tccagttgcc
     1921 attgaaggga ttggtagcgt ccatcatgtt gcgtttggcg tagaaaataa atctgattta
     1981 caacgcatcg acaaacaatt acaagagcgc aattttataa attcaggaat aaaagatcgt
     2041 gaattttttg tatcacttta ttatcgtgac ccaaatcaat tattgattga aattgctaca
     2101 ggggaaggaa acctagatgc aaaagcgtat gaaaatcaaa gtccacgctt tgaagaaatt
     2161 cctttatttt taccgcagta cttaaatttc attcgtgaac aagtggagca ataattagct
     2221 aatcaaatcc atgacgaaga gtaagaggtt gactcataag tcaaaaaata aagaaaaacg
     2281 catcaaatcc attctaaaga atgttgattt gatgcggttc ctatttttat aaactatcat
     2341 tttcgactaa taaaactact tatgagtcag cctctctttt tttcttgatt tttatacctc
     2401 tttctaggta aactaaacat ctgccaaaaa taccgtgtct cattgaaaca ttctcaacta
     2461 tttcaaaata aaggggagta ccaaatgaac gagtatattg aaattatcca cgcaagagaa
     2521 acaacttaaa aatgtcagtc tcaaaattcc caaaaataaa attagtattt ttaccagcgt
     2581 atctggttca ggaaaatcat cgattgtttt tgatactatt acccaagaag ctggtcgtca
     2641 actgaatgac acctatgata gttttacccg tttattttta cctaaataca gtcgtccaga
     2701 ggttgatgag attgataatc tttctacggc gattgtggtc aatcaaaaga agattggtgg
     2761 cagtgcgcgc tcaacgttag ggacgattac taacatcaat gcgttatttc gtgtgttgtt
     2821 ttcatgtttt gcaacaccta gtttaggata tgcaaatgct tattcattta atgatcctag
     2881 tggaatgtgt tctgtctgtc agggaatcgg taagacgatt gcatttttaa taggattgct
     2941 ttatttttcg gctattgata atgctgattt tgtattttct gatccattta ccgcagaagt
     3001 tttgtctgga attgaggaac aggcaaagaa tcatggttat tttgtattgg tgcataatgt
     3061 taattcagca gaagatgtta aaactattca gagaaattgg cgttttgagg ggttcattgt
     3121 tgttggtgta cgtgtaaaag aatttttgga attaaataac gtttttgatg gtcctgttgt
     3181 ttatattgat acgcatcttt caaaagagac attaagagaa cttgaacaac aaatgaatcg
     3241 tttatttgta aatacaaatg attaccaagc tagtacattg gcagtggaac atttgattca
     3301 ttatggtcat gagaaaatag cgtttctttc ttttgactac attgtaggtg aaccaagtgt
     3361 tattcaagaa cgacatcaag cttatatcga tacattaaag aaatatcatt taacctttaa
     3421 atcgcattgg atatataaca actctgaatt tgagcgaatt tatcaagaat tagctgaatt
     3481 tactgcaatt gttgttactg gagattattt agcggctaaa ttagtaaaat ttttaaaaaa
     3541 taagaataaa cgagtgatgg aacaattatc gattattgga tttgatgata ttacttttgc
     3601 agaattaatg gatcctgcgt tgacaacaat acgactaaat ccaggtaaca agggggcgat
     3661 tgcttttcac caactgattg gactggccaa acaagaagaa ataaaaaatc aagtactact
     3721 attagaggga gaattgattt ctcgagactc tgttcacaaa atcaaataaa aaagctctgt
     3781 gaaataagta tagttaacaa taaaatatcc gaacgataga gagaatgaac tgtgatctag
     3841 cagttcctcg tcgcaaattc actagaatta gcattattta ctctaaattg ttcggatatt
     3901 ttttcttgtt tttaattatg attacagtgc ctatttttaa cgaaatttgc ttattttcaa
     3961 aatgtatgat tatatgttag taaacacttt caaatatgaa aagaggagct attatggtag
     4021 gaattaggga tgttgcaaaa cgggcgggtg tgtccattgc aacagtatcg cgcgtgctaa
     4081 atgaggatcc gacactttca gtaaccgatg aaaccaaacg aaagattgca gaatcggtta
     4141 atttttatca ttatgtcaaa aaaagtcccg ttgcaaaaaa tttaacaaat attgcattaa
     4201 taacgacagt ttctgaagta gatgagttgg aagatcccta ttttcgaacg attcgcagag
     4261 ggattcaagt cgaagcagaa caaagcaaag tcaatttgaa gaaaattatt cgtttgtcag
     4321 aaacaccgtt ggagcaagac gatttgctaa aatgtcaagg tgtgttgatt attgggcagg
     4381 tgctatcttc tgtgattgaa gaagtatcag caattaattc gaatgtcgta gtgattgatg
     4441 accctagtat tgaagctgaa gtagatgcag tttatactga tttaacaaaa gcaacgaatc
     4501 agcatttaga tcgattgtat aaaaaaggac accgaaacat tgcgtttatc ggaggaggac
     4561 gtgttcgttt agatagccaa ggaaataaac acgtgtcaga tgatgattat cgaaaaatag
     4621 cctatgagac gtggatgaaa caaaaaggat tagaaaaata tagtcaaatt tatttagaag
     4681 gctggaccac acttgacgga atgcaggcag cagatttact tttgaaaaaa catgctaaag
     4741 ataagttgcc gactgctatc atggtaggaa atgatcctat tgctgtgggg gtttatcgtt
     4801 cacttcaaaa aaatggtcta catattccag aagatatttc gattgtgagt tttgataata
     4861 ttgaagttgc tgaattttta acacctgcat taaatacggt gaatgtgaat acagaagaaa
     4921 ttggaaaact agcagttcgc atggttaatg aacgaataaa agaagttaga aatgtttcga
     4981 tcaaagtgat tgtttctaat aatattattg ttagagaaag tgaaaaaaat atcgattaaa
     5041 aaagtaaaca tccaaaaaag ggtgtttact tttttgttta ctaatatttt tagtaaaaaa
     5101 tctcgacaaa acattaagta aacagttatg gtgttgttaa caaaaagaaa acgcattcaa
     5161 aacaggagga attaagatga aacatttcaa aaaaatagct ttaacaggga tagctgtttt
     5221 aactgggaca ttactcgcag catgtggtgg gggagatagt aattctaaag acgggcaagt
     5281 aactttaagc tatgcgagtt gagatactga ccaagctcca ggactaagaa aaatgttaga
     5341 tgaatttgaa aaacaaaatc ctgatatcaa agtagaaatg gagacaacgc cttgggatca
     5401 atattgggtt aaattagaag ctgcaacaac gggaggtaat atgccagatg tagtaaccat
     5461 gcactctagc gaatcctata aatatatgtc acagaatgct ttgatgggac ttgatgatgt
     5521 tatcaaagaa aatgatattg acatgggaaa ctttactgaa ggaattgctg atttctatac
     5581 gcttgaagac gaactatacg caatccctaa agatgcttct gtagtggggc tatggtacaa
     5641 caaagaatta tttgataatg caggtgtcga ttatccagat gaaacatgga catgggaaac
     5701 actcagacaa gctgcaattg atttaacaga tgaatcaaaa ggcatctatg gttttgcatc
     5761 acatattgga acagagactg gctactggcc atttatttat caaaatgggg gagaagtatt
     5821 tgccgatgac aatacaaaat caggtttgaa taccccagaa gcacaagaag ctttagcttt
     5881 ttatcgagat attgcacttg ttgatcatgc ttcaccaaca attacagaat tacaagatcc
     5941 tgataagtta agtcgttttc aatcaggtag attagcaatg atgattgaag gaaactggtt
     6001 tgcaccggga tttttgaaaa atgactatct agttgaaaat gttgcttctg ccgtgttacc
     6061 taagggaaaa gttaatgcaa caattacaaa tggacttggt tgggctgcca gtgcgagtac
     6121 aaaataccca gaagaagtga aaaaactaat ggcattttta gctagtgagg acgccaataa
     6181 aatccaagcg gaaacggggg catcaatccc agcactaaaa ggctttgaag acgagtgggc
     6241 tgcttcttca gatacaattg atttgagtgc ttttggaaaa atgttggagt atggagtccc
     6301 tcgtccatac aataaagatg gattacgagc tgaacaagca gaagttcaaa ttattaaccg
     6361 tattctgtct ggtgaagtaa ctgttgaaga tggaaccgct caaattgaaa aagaagtcaa
     6421 tgcgatattg agcggaaatt aaattagtta attatacaat atacaggcga aaggattcta
     6481 tttcgtctgt atattaatgg atgaatacca aaaaggggga tattatgaaa aatcgaattt
     6541 ttggaaaata tcgtaaagat caagtgatat ggggctatat ttttattttt ccaacggcat
     6601 taggattaat tttattaaat atatggccag caattcaaac agcaatttta agttttcaaa
     6661 aaacggtagg gttcggtgat actgaatggg tcggattaag aaattaccaa aaaatgtttg
     6721 cagacggtga agtttttcag tctttattaa acacattaat ttatgcagtg gtttcgatac
     6781 ctagtattgt tgtattatcc ttgttggtgg cagttttaat gaatagaaaa gttaaaggat
     6841 tgtcgattta tcggacaatt tattttctac cagtcgttgc tgcaccatcc gcagtcgcaa
     6901 tgatttggcg ctggatgttc aataatgatt atggactgat taataacatg ttggctaaaa
     6961 taggtctcga tggaccagca tggttaacgg atccatcgat tgcgatttat tctattatca
     7021 ttgtaggagt ttggagtgct attggttata acatggtgtt attactagcc ggcttataag
     7081 aaattcctaa agattattat gaagcagcgg aaattgatgg tgctagtcca atccagcagt
     7141 ttttcaacat tacgttacca ttagttacac caacattatt ttttgtagtt gtaacaacag
     7201 ttatcaatgc tttccaagta tttgatgtta tttttatgat gattactcct aatagtaccg
     7261 ccatgtttaa atcacaatca ttagcctatt tattctataa acattcattt attttaaatg
     7321 acaagggata tggttcggca atcgttatgt tccttttagt gattatatta attattactg
     7381 caattcaaat gaagttgcag aaaaagtggg taaactatta aggaggctat caaattatga
     7441 aaaataaatt tttttcaaat gcgccaatcc atatcatgct tattttaggt ggtattgcaa
     7501 tggcattacc ttttatttgg atgattttaa cttcagggaa aacgttggtt gaatctaccc
     7561 aaattccacc tacaattttc cctgagaaat ttcagctaag taactatcaa caagtacttg
     7621 atttattacc attcatggct ttttatatca atacattttt aatggttgtt ggacgagtga
     7681 ttggctcggt tttattttca gcaatggctg catatgcttg tgcgcgtcta agttttccag
     7741 ggaaaaatat ccttttcagc ttagtactta ttcaaatgat gattcccggt tccattttta
     7801 ttactccaca gtatttatta gcacaaaaat tgggtatttt aaatacaatt ccagcattaa
     7861 tattaccagg ggtagttagt gcgtttggta cgtttttatt aagacaattt ttcttaggtt
     7921 tacctgatga attggaggaa gcggcctatt tagaaggtgc caatatttgg acgatctttt
     7981 tcaaaattat gttgccgctt gctaaatcag gattggttgc acttggaata ttcacagcgt
     8041 tgtttgcatt taaagattta atgtggccat tgattgtcaa tacttcaatt gataagatgc
     8101 ctttagctcc gggattagca aacttacaag gacaatatgc cacgaacttc ccacaattaa
     8161 tggcaggttc gttattagca atttggccaa tagttgtgat attcatcgtt ttccaaagaa
     8221 aattcattga aggaattgct acaacaggta gtaaattata aaactattaa ttagtgattg
     8281 gagagtaagt acatgacaaa aattacattt attggtgcag gaagtactat ttttgcaaaa
     8341 aacgtattag gcgatgcgat gttaactcca agtctacaag atgcacatat tgcattgtac
     8401 gatattgatg aaaaacgact aaaagaatca aatttaatgc ttaaaaatat taataaaaat
     8461 tcgaatgaaa atcgtgctga tattgtttct tattatgatc gcaaagaagc gttaagagag
     8521 gctgattttg ttatcaatgc tattcaagtg ggtggttata aaccttcaac agtgattgat
     8581 tttgatattc ctaaaaaata tgggttgcga caaactattg gtgacaccat ggggattggt
     8641 gggattttta gaaccctacg gacactacca gtaatgttag actttgctaa agaaatggaa
     8701 gaagtttgtc caaatgcttg gttattgaac tatacaaatc cgatggcgat gttaaccatg
     8761 ggtgttttaa aagcgacgag tattaagact gttggtttat gtcatagcgt tcaagtatgc
     8821 gtaccagaat tgtttgagca tttaggaata gccgatcaat atgacttaaa tgactttcaa
     8881 tggaaaattg caggcattaa tcatatggca ttcttgttgg aaattacaaa aaatggggaa
     8941 gatttctatc caacaattcg tcagttagct gcagaaaaac caaatccaca tccagattct
     9001 gtacgttttg aattgttgaa acgttttggt tactatatta cagaatcaag tgaacacaat
     9061 gcagaatacc atccatactt tattaaatca aaatacccag aattgattga cgaattaggg
     9121 attccgttgg atgaatactt acgtcgttgt gaacaacaaa ttaatgattg ggaaagcatg
     9181 cgagaggaca ttgtaaataa tggggagtta acacatacga gaagccgtga atatgcttca
     9241 tatatcatgg attctattac gacaggaact ccgtcagtga ttgcaggaaa tgtcttaaat
     9301 aaaggcttaa tcacaaactt accgacagat gtttgtgtgg aagtaccttg tttagtcgat
     9361 aaaaatggcg tgcaaccaac ctatgtcggt gaattgccaa cacaattagc tgctttaaat
     9421 cggacgaata tcaatgttca agaactgaca gtagaagccg ctttaacact agataaatca
     9481 aaaatttatc aagcagcgta tttagatcca catctatcat ctgaattgtc tttaacagat
     9541 atcaaaaatt tagtggatga tttaatcgaa gcacatgggg actatttacc tgaatataat
     9601 taaaaagaag ctgaaagagt aaggaatttt caattcctta ctcttttctt agttaaattt
     9661 agtaaaaata ttgacaaaac acttagtaaa cagttacatt agtgttaaca aaaagaaaac
     9721 gcattcaaat tgtataagga ggagcataaa atgaagtggt ctaaaaaaat tattttagct
     9781 tgtatagcac taggagcaac gatctctttg actgcttgtg gaaaaaatca ggaagatgca
     9841 agcggtaagg tagaaataga gttttttaat caaaaaaaag aaatgactca aacgattcag
     9901 gagattgcta aagattttga agcaaaaaac cctgatattc atgtaaaagt tgtggatgta
     9961 ccgaatgctg gtgaagtaat taaaacacgt atgcttgcag gcgatgtacc agatgtcatt
    10021 aatctttatc ctcaaagtat agaattgaaa gaatgggcga aagctggtta tttagaggac
    10081 ttaaccgaag aaccgtattt agagaatatc aaaaatggat atgcacaacg ttttgctatt
    10141 gaggatcgtg tatatagcat accattaacc gctaatgtct atggttttta ctataacaaa
    10201 actgcttttg aggaaatggg gattcaagca ccagaaactt gggcagaatt tgaaaaaata
    10261 gtagctgaga ttaaagatca aaacaaagta ccgtttgcga ttgcaggagc agaaggctgg
    10321 actttaaatg gttatcacca actagctata gcgactgctg ctggtggtga agaggaagcg
    10381 aacaatgttt ggcgtttctc agaagttaat ggaattaatg ctgaaagcaa agaaatgcaa
    10441 aaagatttta atcgattaga tttgttaaga gaaccaaaag ctttgcaaaa caactggcaa
    10501 ggtgccggtt ataacgatac agtagttact tttacaaaag gtgatgcgtt gattatgccg
    10561 aatggttcat gggcaatgcc gatgattcat tcacaaaatc cagattttga agtaggaact
    10621 tttccttttc cagcagatga agcaggtcaa agtctaacga ttggcgcagg agacctagcc
    10681 ttatcagttt ctgcaacttc tcaacataaa gaagaagcca aacgttttgt agaatatatg
    10741 acaacacctg aagcgatgca gaaatattat gatgtagatg gtgcaccgtg tgctgttgag
    10801 ggcgttatcg agaatactca ggattcacca ttaagtggtt taactgaact tgcttttact
    10861 gatcgtcatt tagtttggtt agccaaagat tggaatagtg aaaatgattt ttatacctta
    10921 acaacaaatt atttacacaa tggcaatcaa aaagccatga ttaacgcatt aaatgctttc
    10981 tttaatccaa tgaaagctga cggaaggtag gaaaataaaa tgaaaataaa agaaatttta
    11041 aatcgttact gggcaatcat ttttgtagca attccaatta ttttgcagat gatttttttc
    11101 tactttccaa tggttcaagg tgctttttac agtttaacta attggactgg tctgacttat
    11161 aattttgatt ttgtgggttt gaacaattat aagattcttt tttctgatcc gaagtttatc
    11221 aaatcgattg gcttcacttt aattgtgacg ctttgcatga ttgctggaca aattggtttt
    11281 ggtattttga ttgcgcgggc gttgaacgca aatattaaag ggaaaacatt ctttagagca
    11341 tggttctttt ttccagcggt cttatcgggc gtggttgttt ctttagtatt taaacaaatt
    11401 tttaactatg gtttaccaaa aattggtagt atgttaggca ttgaattttt acaaaccagt
    11461 cttttaggaa caacatgggg agcgattttt gcagtaattt ttgttttact ttggcaagga
    11521 attgccatgc cagtcatcat tttcttagcg ggttttcaaa gtattccaca agaaattatt
    11581 gaagctgcta gaatggatgg ggcgaatgat aagcaaattt tttggaatat tgaaatcacc
    11641 tacttattac caagtatttc aatggtattt attatggcat taaaaggtgg cttaacagca
    11701 tttgatcaaa tttttgcttt aactggtggt ggaccaagcg atgccacaac atctttgggg
    11761 ttacttgttt ataattatgc ttttaaaaac aatcagtttg gttatgcgaa tgctattgct
    11821 ttagtcttat ttatcttaat tgggattgtt tcactggcac aattaaaatt atcgaaaaaa
    11881 tttgaaatct aggaggtttc ccaatgaaaa catcaaaaga aaaaaatatt tctaaatact
    11941 tgcttttatt attagggggc ttcatgattt tagttccctt agtttcaacg ctattcggtt
    12001 catttaaaac aacacccgat attatgaata atttctttcg ttttcctaat ccagcgactt
    12061 tggaaaattt ccgaagattg ttagcggatg gaattggtca ttacttttgg aattcggcaa
    12121 tcatcacaat cattgcagta gttgctgtga cagcaattat tcctatggct gcttattcac
    12181 tagcaagaaa aatgactcgt gggaaagcat acggattgat gtatttattt ttaattttag
    12241 gaatttttgt tcctttccaa gtaattatga ttccgattac cgttatgatg agtaaaattg
    12301 gtttagcaaa tatgtgggga ttaatcttac tctatctcac ttatgccgta ccacagacac
    12361 tatttttata tgttggtttt attaaactaa atgtgcctat cagtctggat gaggctgctg
    12421 aaattgatgg ggctagtcac tttacaactt atttcaaaat tgttttccca atgttaaaac
    12481 caatgcatgc gacgactatt attcttaatg ctctatggtt ttggaatgat ttcatgctac
    12541 cattattaat tttaaatcgt gattctaata tgtggacact accattgttt caatataatt
    12601 atacgggaca atattttaac gactatggtc caagttttgc ttcctataca gtaggaattg
    12661 tcacgattac actagtttat cttgctttcc aaagaagtat tatagctgga atgagcaatg
    12721 gagcagtgaa ataaccaata aattattctc attataaagg agttcataaa cttatgatta
    12781 tatttgacaa tcacacacaa acatttcatt tacaaaataa aaaaattagc tatctattag
    12841 gaatcgaaga aaataattat ttaacgcatc tttattttgg aaaaaagatt acgcactatt
    12901 ctggtgggta tcgctacccc cgaacagatc gttccttctc acccaacaat gcaaatgcgc
    12961 aagatcgttt attatcttta gacacattac cattagaatt tccaggatat ggacatggtg
    13021 attttagaga accggcgcat aatattaaat taggaaacgg tagtcgtgta aatgattttc
    13081 gttatgatag ctacgaaatt caaaaaggaa agcccagctt agcgggattg ccagccttat
    13141 atacggaaga tgatgatgaa gctgaaacgc tgattattca attgaaagac gcgattagtg
    13201 gattgacttt acagttgttc tacacaattt atcaaaatca cagtgtaatt attcgttcta
    13261 cgcaattagt aaataatagt gatgaaacag tggagattaa ccgcttagct agtcaatcaa
    13321 ttgattttcc aaatcgtcca ctcgagttaa ttcatttaaa tggtacctgg gcaagagaac
    13381 gtcaaatgac tagagaaaaa attcatacag ggataaaagt attagatagt aaacgcggat
    13441 caagcagcca tcaacaaaat ccgtttgttg ctttagtaga tgccaaaaca gatgaatttc
    13501 aaggagaggc atatggattt aatttagttt atagcggtaa tcacgaaacg gtgattcaaa
    13561 aagatccatt tgaccaaaca cgggtcatta tgggaattaa ttcatttaat tttggttggc
    13621 aactaaaaac tggcgactca tttcaaacgc cagaagtcgt gatggtttat agtaatgaag
    13681 gtctgaatac gttatcacag acgtatcatg aattgtataa tcaccgttta attcgtggaa
    13741 actatcgttt aaaagaacgt cccacgttaa tcaacaactg ggaagcaacg tattttgatt
    13801 ttaacgaaga aaaaatcatg aatattgtcg atgatgcgaa gaacttgggc attgaaatgt
    13861 ttgttttaga tgatggttgg tttggcggtc gtgaaaatga cttcacttca ttaggtgatt
    13921 gggttgaaac agaaggcaaa cttgcttgtg gtttggaaaa tttagccaag caagtgcatg
    13981 ataacgggat gaaatttggg atttggtttg aaccggaaat gatttctgaa gatagtgaac
    14041 tatttcgagc acatccagat tgggcattgg gtattccagg tcgtgaccgc tcaattagtc
    14101 gaaatcaata tgttcttgat ttttcaagac aagatgttcg tgataatatc tatcaacaaa
    14161 tgacggcgat ttttgatcgt gtaccgattg attatgtgaa gtgggatatg aatcgaaata
    14221 tgacagaagt ctattctgtc ttgttggact caacgatgca aggtgaagtg gctcatcgtt
    14281 atatgttagg gttatatgaa tttttagaaa agttaacaac gaattatcca actattttat
    14341 ttgaaagttg ttcgggtgga ggcggtcgtt ttgatgcagg tttcttgtat tacatgccac
    14401 aaacttggac gagcgacaat accgatgccg tggctcgtct gaaaattcaa tatggaacca
    14461 gcttagtgta tccaatttca agtatgggtg cgcatgtttc agcagtccca aatcatcaaa
    14521 caggaagaga aacgagttta actattcgtg gcaatgctgc gatggctggt gtttttggtt
    14581 atgagctaga tctaacgcaa ttaacttctg aagaaaaagc agaaattaaa gaacaagttg
    14641 ccttttataa aaagcatcgc caacttttgc aatatggaac tttttatcgc ttggaaagtc
    14701 cgtttgaagg caatgatact gcatggatgt ttgtctcaaa agaccaaaca gaagccatgg
    14761 tcttttattt ccgagtatta gcagaagctg cgcatccatt agtcacattg aaattagcag
    14821 gattagcaga agaagcaact tatcaaatgg aagatgtaac atttgctggc gatgaattga
    14881 tgaatctcgg tttttatatt gactcagaac tacatggtga ttatgcgaca caacgctttt
    14941 atttgaaaca gatatagtag cttgaattta caatataagt gcaacaccaa aagagactca
    15001 ttccaaacga agaaaatatg ttttatttac acgcatttac taaaaagcag cctgatttga
    15061 attgggaaaa tgaagaagta cgtgaagaaa tctatgcaat gattaactat tggttagata
    15121 aaggactagg cggatttaga atcgatgcga tattaaacat caaaaaaaaa ctagagtatg
    15181 gcatctttga atctgatgga gaagatgggt tagccttcat tgggccctgg attcttaatc
    15241 agtcgggcat tgaagtgtgg ttaaaagaaa tgagagagcg gacatttaaa ccacataata
    15301 gtatgacggt agcagaagcc gatgttccta atgaacgttt agatgaatat attggtgaag
    15361 atggctatta ttcgatggtt tttgatttta gttatacgga tattgatgta cctgaaactg
    15421 gtgaatggtt taaagatagc caatggacat ggacggatat gcgtaccaat atttttacga
    15481 atcaattagt tacgcaagat aaaggttggg gcgccttata tttagaaaac cacgatcaac
    15541 cacgttcaat taataaatat attccagaag aatggatcaa tgattatagt aaaaaaatgt
    15601 tggcgacgct ttttatgtta ctaagaggta ccccttttat ttatcaagga caagaactag
    15661 gaatgaccaa catagaaatg gcatcattag aagattttga tgatgtagct acgcattctc
    15721 agtataaacg ggcattagaa tatggattgg caccagagca agcattgaaa gctgtcaata
    15781 aacgaagtcg ggataattct cgcacaccta tgcaatggaa tacgcaaaaa aatgccagat
    15841 tctcaacttc tgataatgta tggttaaaag taaatcctaa ttatccagaa ctcaatgcag
    15901 aagctcagtt aaccaatcaa cagtcggtat tcaattatta tcatcaatta attaaattaa
    15961 gaaaaaatag tgtatacaaa gacgtgctaa tctacggaca atttctacca gtgaaagata
    16021 aaaatgaaca tattttgctt tatgaacgcc aattagaaga taaaatcgta ttagttatct
    16081 taaacgttac agcaacagaa caagaatatt atgtagatga acagtaccaa caagtattaa
    16141 tcaataatta tgaagatgtt ttattagatc aaagtcgaaa attgcgttta cgaccgtttg
    16201 aaagtattgt attagctaat tatggaggac aattatgaaa attaaaaacg aagcaatgct
    16261 catcacctat gcagatagtt taggaaaaaa catgggcgaa ttaaaacaag tcttagacaa
    16321 acatttacaa ggtgttattg gtggtgtaca tctgttgcct ttttttccat cgacaggtga
    16381 tcgaggcttt gcgccgagtg attatacgac agttgatcca gctcttggaa catgggaaga
    16441 tgtggaagca ttaggtgaag attattattt gatgtttgat tttatgatta atcacatttc
    16501 tcgtgaatca aaatttttcc aagatttcaa aaaaaaccat gagcagtcac catacaaaga
    16561 aatgtttatc cgtattcatg aatttttccc agaaaatcga ccaacacaag aagatattga
    16621 tttaatctac aagcgtaaag acaaagcgcc gtttcaaacg gtagaatttg cggatggtac
    16681 gacagaagag gtttggaata cctttgggga agaacaaatt gatttagatg tgaccaaaga
    16741 agttgtgaaa gaatttattc gagaaaccat caaagatatg gcgaaccatg gctgttcttt
    16801 aattcgatta gatgcgtttg cttatgcgat taaaaaatta gataccaatg atttcttcgt
    16861 ggaaccagat atttgggaac ttttagacga agtgcgtcaa gaagcagcga aatatgacgt
    16921 cgaattatta ccagaaatcc atgagcatta ttccattcaa atgaaaattg ccaatcatga
    16981 ttattatatc tatgacttcg ccttgccaat ggtcactctg tattcacttt atagtggaaa
    17041 atcagaacgt ttagccaatt ggttgaaaat gagtccgatg aagcagttta caacattgga
    17101 tacgcatgat ggaattggtg ttgtggacgc tcgtgattta ttaacagatg aagaattgga
    17161 ttacacctct gaggaattgt ataaagtcgg ggcgaatgtg aagaaggtct attcaagtgc
    17221 caattacaat aatttagata tttatcaaat taacagcacc tattatagtg cattaggcga
    17281 taatgaccgt agctatctgt tagcacgtgc gattcaagta tttgcgccag ggattccaca
    17341 aatttattac gttgggttat tagcaggaaa aaatgatatt gaactgttgg aagcaacgaa
    17401 agaagggcgt aatattaatc gtcattacta tgatttagcc gaaattgaag aagaagtgca
    17461 acggccagtg attcaacaat tatttgcact tttaaaattt agaaatgaat ctgcggcgtt
    17521 tgatttggat ggaacgattg aagtagcaac gccatcagaa tcagaaatag tgattacacg
    17581 taaaaataaa aacggtagtg atagtgcaac attaacggct aacttggata cgaaagaatt
    17641 tatcattgag tctaaagata taaaaatttt cactagtgtt gcattaaaat tttaacctat
    17701 tccatagaac aaaaaatcct ttatactagc acttggatga cttatccaag accaataaaa
    17761 aggactcata catggataag tataaaacaa atacagcatt taataaatgg ttttctgcca
    17821 taaaattagg aaaactttct gtcaactccc aaaaatgtat ttttgattac aattcgtatc
    17881 gtaaaaaact gtcttttgaa gctgtgctca agctctttct ctacgcagtt aatgaagaaa
    17941 aagaaagttt gcgtgatttg agtacagctc ttatcgaccg atcgctccaa ctagaaaccg
    18001 atgtgtcatc gattagtcat acccaattgt ctcgagcatt taatgcactt gaacctaaag
    18061 tgttagaaga aatttttcaa caactgttag aaaaagttca acatcaaatc aaaccaacca
    18121 agcgaaatca tctgtatctg attgattcca gtacgttttc gcttagttta aaacgtcata
    18181 agtgggcgac tttccgtcaa acaaaatcag gtgtcaagtt acacttaaac tattgttata
    18241 tggacgatac tacgatgtat ccaactgatt ttaccttaac aaatgcccat gaacatgatc
    18301 tcaatcaact accagtattg gtgaatcaac cagaggcaac ttacgtgttt gatcgtgggt
    18361 attaggactt tgaaaagatg gatcagatgc attgggatgg ctatttcttc gtcactcgga
    18421 ttaaaaaaaa caccaaagtt cacgtgatag atactctgga aacatcgcca gaaacagaaa
    18481 ttctacgaga cgagctggtt cgtttaggat ctaaaaccta tctaaccgcc aatttccgac
    18541 tagtcactgt tcaagataag aacggacgtg tgtttcaatt tatcaccaat cgaatggacg
    18601 tctcttcaaa agaaatctct gatatgtatc acgctcgttg gcaaatcgaa ttgtttttca
    18661 agcacatcaa acaacacatg accattaaaa ccttcttttc tcaaagtgaa aaaggcgtgc
    18721 agaatcaatt gattttaacg atgatttccg ctctcctcac gtttctcatc aaattggaga
    18781 cgaaaacgga aaaatcagtg ttccaaatca aacgattctt tcgttattta ctgtttcagc
    18841 cctttgaatg ttgtctagaa aaattaattc ccacatgaga aaaaagaaat ttggctcgtt
    18901 acttttggtt ttcagttgaa taacagataa aaaattttct ggaaaaagtc atcctctgcg
    18961 tcagcacagt tttttttgac ttattttcag aggaaatagt tttcagaata ttctaaaatg
    19021 ttttatgcaa cactagtgat attttttaga attagatttc taatgtgcat tttttgagta
    19081 ttaaggagca agtatacaaa gatttataaa gctgattaaa tttgaataaa aatatgcagg
    19141 aacgctacta tttttagtag tgttcttttt tatatttgaa taaaaaatgt ggtggttaaa
    19201 tggtggttat aacaaaaaat gaattaatga aattaggtta tgggaagtat cagtctgaga
    19261 gaatcatacg acaggcaaaa gcaattatgg cttcaaaaag ctatacctat tacgaaaata
    19321 gaagattagg actagtacct gttgaatctg tagaagaagt tttaggtatg aagatagagg
    19381 tagaggagga ttttcagaat catggttaat tttaaaaaag ataaaaatgg gaaatatcat
    19441 tttactgcta gtttgggatt cgacaaacga acagggaaaa gagtacaaaa aaacgtagag
    19501 gggttaaaac agttaaagaa gaaaaaaagc gtataccgaa cttgtttcta attatggaaa
    19561 agaagcagaa acttctcaaa gtactatgtt gtttgaggag tttttttata aattattcct
    19621 accttattat caagggaaag tagaagaaag aacatataaa aatcggttat ctacaatcaa
    19681 aaaaactttt cttatttctt taaaatggag ttaagagaaa tacgtccaat tgacattcaa
    19741 aagtggcaaa ataatttatt gagcaaatat aaaaattctt atgtaagaaa catgtatggg
    19801 atttttcaga tgtcattaga tcgagcagtt gttttgggac tacttgaaaa aaatcctgca
    19861 aaagttattg gaaatgtgaa gaaaaggaaa actacagttg atttttggac aaaagaagaa
    19921 tttacaaaag ttatttcaac tttttatatt gatgatttgt accaacattt tggttttatt
    19981 tgtatgtggt tactttttat gaccgttatg cgtttgggag aagccactgc attaacttgg
    20041 aaagatattg attttgaaaa taaaaacttg cgtgtgaata aaacactcta ttataagaga
    20101 gccaaaacct atgagtttgt agaacccgaa acggcttcta gtattcgtac aatcgaacta
    20161 gacgacaata caattacctt tttaaaagct tggaaggagc gtcaagtttc aataggaggc
    20221 atgtcgtttg tactttctta taatggaaca cctactcaga aatatacaat ccgtcatatt
    20281 atgagaagac atgcaacgat cgttggtgtt catataatcc gcatacacgg attaaggcat
    20341 agtcatgctt ctttgcttat atcacaataa aaagatgcac ttcgaattaa agaaaggtta
    20401 aaacatgctg atgtacaaac gactttagga acttatggtc atttgtatct aaattcattg
    20461 agagagataa caaatgatcc cacagattat atccaaacta atttttctaa aatcaaaccg
    20521 acacctattt acgataataa aaaataaatg ataaacaaaa gtaggatcac accaaaagaa
    20581 acacactaga aaaactataa tacaggcttt tctagcgtgt tgtttcttat ttccgcctat
    20641 ttatacatta tactcataaa gcatttaatg catcgatcgt agccgcattg tctatatggg
    20701 tatataaagt tgttgtattg gtacttgaat gtcccaattg ttgggcagtt aataccaatg
    20761 aatttgtctg ttggtagagt ctagtagcta atgtatgacg cagtttgtga gggctgactt
    20821 gaattctaaa gccttttgaa tattttgcta ccatccgttc gattgcaata ccggatatac
    20881 gcttggcttc tccttggtaa attgctagaa ataaagcttt ttcgttttct gttactttat
    20941 atcgttcttt ccgaatagct agataattag ctaaatattc cattgcgaat gctgctatat
    21001 tgacagcatc tcttttattt ccttttctag ttactaccac attattctta tctaaagata
    21061 ggtcatctaa attaatattt ataacctcgg agagtctcaa tccagatcct aaaatcagtg
    21121 cattgatcgc caggtctctt tctacatctc gttgataata gatcaaagct cgtttactca
    21181 aagtattttt atattcattg gcaatataat ctagataatt ttgtgtatcc ttatctagaa
    21241 ataatttttt ctcaatggca ttggcacgtg cagctaacgt agttttatct gtgatggttg
    21301 ctacttgatc cataggatta ttgtctaagt atggttttcc tagaggatta ttggaacttt
    21361 tcgaaagata tttaaataga acctttaatg ccgtgatatt tctattgata gtagaagtag
    21421 atagacctaa gttattatta tctttgagct tagtttttgt tgtctctttt tttacatttt
    21481 cttttgtgcg acgtttcaaa tgagatttgt acaagtttag gtcataggca gttaactgtc
    21541 ttatcgaggt gatagaagta tcaggaacga tagactcact cagaagccat tcataaaaga
    21601 gcttataatt ttttagatat tctaaagtgg ttcgaggtga ttgatcttta tcctcacgat
    21661 cttgaacaaa atcttttata taatcgggca tatgaagtat gattgtatct attttttgat
    21721 atatttctgt atttttcatg tcattcatcc tttcaataag taggggagaa gagtatctct
    21781 ataattggac tataccaatt atagaatgtt ttgtcaattg gtatgctcta aaatttatta
    21841 atttgtttca aaaaaagcat ataaacaggt atacgtttaa taatttaaaa taaatggtat
    21901 acataaatag ggaaggaaat agaagggagc aatctaaatt ttttgaattt tcttaattaa
    21961 ttatatagaa agaacaatct ttctatagag ttagacatga gagggactat gcttgattta
    22021 aaatcaacaa gcgtatatac tgtatataca aagaaaaagg agggagaaga ctatggcaat
    22081 taaagaaaga aaatttaggg aagtggggaa ctcagtagta ttaactattt caaaggagtt
    22141 tcttaaagaa aatgggttaa atcccggaga tacggttttt ttagatgaag aaaaacttcg
    22201 agcggcaatt acaaaaaaac aagccttatc tgatgaaatt gatttagcaa tatctcaagc
    22261 attaactgaa tatgatacta cttttagaga gcttgtcgat aaatgagtat tcattaccta
    22321 gaagccaaag atattataaa aatgaatgta atccaaataa aaaaatactc tcctaatgaa
    22381 ccccttggtg taaaggatgc gaatgcttta gaaatgtgtg tagggcaact tcgagcctca
    22441 gcttttggtg aagaggttta tccttcgatt tatgaaaaag cagctatcct acttatacaa
    22501 ttgataaaga aacatccttt tcacaatgca aataaacgta ctgctttctt agctactttt
    22561 gtctttttga aaatcaatgg acagctttta gctattgatc aaaaagatgc tgtaaattta
    22621 gcggtatata ttgctacgta tgataaggat ttcgatcaac taaaatatga agtgatcaac
    22681 actataaaga cacatacgca gcccatttaa ggagttactg tatgtgtctt tatagggtta
    22741 ttagctgcta tagcgaaata attgaagtaa attacaaata gctataattc aaatccaact
    22801 atatagaaaa cgtaaatttt ctatatagtt ggattaagat aacgactatt tattttatca
    22861 tatttttact ataccctata cttttacttg gtatatttat gaataatcgc aaatttaccc
    22921 ctatactact agtttgtaag ttagattaat aaaaatacta aagttatttg ttcttttatt
    22981 aaatacacct acaacttata aattgatggt atttagataa cacgaaagaa taaaaataac
    23041 agctgatagt aaagtttgtt gacgattgct actcaatcga aagtgagtta gtgcgtatga
    23101 acttgcttct gaaaacttat gaaatgaaag accttttaca tcttgcagaa atcgttactg
    23161 ggattaaact aagcaataaa aactaatgtt cccctcattc tttgaacttc tactatttga
    23221 tttatttatt ctgataaatg acgatttcac cttcaggatc ttcaaatccc gtatagaatt
    23281 tatttaagat ctcttcagta tcagtaatag gataggcgat aggccacata ccctttgatg
    23341 gttagaataa actgctcaaa atctgtatcg tatgttggct ttagcatatt aacaaaggct
    23401 atctccaaat tataaaccat aagcgttgaa tcgttcttaa caatttcaat tcttcctaac
    23461 ccaaagtcag aagatataat taccggactt gccttaccct tcatgtgggt tgttgagatt
    23521 ccatatttaa agggaattgt cggtactatc ggcggtctga aaaacatccc aaaaataaaa
    23581 aaatctttcc cctgctagtc tcctaagtcc ctttgtagcg gatatggcac cataatctca
    23641 ttttatcgaa gtgagtcatg gtttatctgt tggccaacca aaattgatac aatctaacga
    23701 tgcaccctct acggcattct aggggagtgc acttgcattc acccaataaa aaccggcagt
    23761 tagcaaagaa cttatgtagt cgtatgttct tactgttaac atacaagagg tctcctttcc
    23821 acaattgctt agcagtaaac gggaatttac aaagctaatc tcttccattt tcttatcttt
    23881 gttctaaaag tcccaaatgg agcaactgta tttacatgaa taaatttata tacttcccat
    23941 acagccgttt tggttgcctc gtctgcccat tttcttttgt gtgcagtgaa tagatcttca
    24001 tcactcattg aatcaatcat catgttaata tcatcaatat tacgattgag aatttcctct
    24061 aattctttca atggtagatg tgcataggta tttgtaaacc acttatataa ctctcctaac
    24121 tgattccatt taaattgatc agaaggcgtt ttaacagata atccatttct ttcatcattt
    24181 tcccatttta gaattaaatt cgtccaacca acttgatatg ctaaattttc agcaggtgtt
    24241 ctatccactt cctcaactct tttatccttc aattcttcag gaatagtttc aaattctaaa
    24301 atatatttag tataagtcct atttatttct ttttttaatt cttctttatt tttatatgtt
    24361 ctcattatat tacctccata aattcctaat tgtctccttt aattcatcta taatttcatc
    24421 cacgatattt taatccgttc tacaatgcat atctgatatg cattgactgt ctaactcata
    24481 tgtgaatgat ttataaaata tcccaacgtc tcatctaaag aaatgttgat cgtcagcaag
    24541 gagctaaaaa atacgaatat atttcttttg tagtaaaatc ggactggttt gcatatcatt
    24601 ttcttcgtaa atatcaaaat catgttaact actatcaatt actaataaaa actaccactt
    24661 taagcgttaa gaactgttaa gtttagttaa gtgaggatag ttcacaaaat ccattgttaa
    24721 acttcacgaa agtggtaaaa ctcaaaatgc tttatatagg attacagcat cgctctttct
    24781 tcgattgcgc gttgggtaaa aaatattatg aagtaaaaat tgacgatgac acgttcctta
    24841 cggctcatca gatgaaacag ctacaaaaac gaaatgatca actcgaagaa aatttaattc
    24901 taaaaaagcg attgccatat tcacgcctcg ctcgacgaac tattaaaggt caagatttac
    24961 ctgaagatca tcctttttag gaaattgaag ctttttatgt tgcacaatgc atttataata
    25021 ctacaatgat gttttcacca gatattcttc tagggtgcgg tgtaatgaaa cagatacact
    25081 tgcaaaagaa aattcaccgc gaatttacta aaattatgaa taattatgtt aatcttccga
    25141 aatttttttc caaaattaag ggatcaagct ggtgttatag attgtttaag gttggcaaaa
    25201 aaataacttc tttttaaaca attatagaaa accgatactc tgttaagttg gttgacacgg
    25261 tgtcgatttt tatgactttc ttattctgaa acttcactaa cggacagtac ctaaaaagtc
    25321 tatagtatgg acgtttacga gtactatttt atcaaaaatg ctgctcattt caacttatat
    25381 gttttagtga actaccccca cttagcttgg ataggctaca attaactaga cagaaaaatt
    25441 aaggtgtgta gactagaaga aaacatacca ggaggaattt ttatgtctaa gagaacacga
    25501 agaacttttt cacaagaatt caagcaacaa atcgtcaatc tttacttagc tggaaagcca
    25561 cgtgtagaaa tcattcgaga atatgaacta ac
//
LOCUS       DADVXE010000037        24259 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.038, whole genome shotgun sequence.
ACCESSION   DADVXE010000037 DADVXE010000000
VERSION     DADVXE010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.038"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(44..1339)
                     /gene="purB"
                     /locus_tag="KB913_001641"
     CDS             complement(44..1339)
                     /gene="purB"
                     /locus_tag="KB913_001641"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBB6820005.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1352..2476)
                     /gene="purK"
                     /locus_tag="KB913_001642"
     CDS             complement(1352..2476)
                     /gene="purK"
                     /locus_tag="KB913_001642"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBB6820006.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2469..2957)
                     /gene="purE"
                     /locus_tag="KB913_001643"
     CDS             complement(2469..2957)
                     /gene="purE"
                     /locus_tag="KB913_001643"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBB6820007.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3373..4680)
                     /locus_tag="KB913_001644"
     CDS             complement(3373..4680)
                     /locus_tag="KB913_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBB6820008.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4683..5264)
                     /locus_tag="KB913_001645"
     CDS             complement(4683..5264)
                     /locus_tag="KB913_001645"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBB6820009.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5380..5477)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5836..7128)
                     /locus_tag="KB913_001646"
     CDS             complement(5836..7128)
                     /locus_tag="KB913_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6820010.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7125..7748)
                     /locus_tag="KB913_001647"
     CDS             complement(7125..7748)
                     /locus_tag="KB913_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820011.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7751..8587)
                     /locus_tag="KB913_001648"
     CDS             complement(7751..8587)
                     /locus_tag="KB913_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6820012.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8604..9491)
                     /locus_tag="KB913_001649"
     CDS             complement(8604..9491)
                     /locus_tag="KB913_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6820013.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9507..10790)
                     /locus_tag="KB913_001650"
     CDS             complement(9507..10790)
                     /locus_tag="KB913_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6820014.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11473..12156)
                     /locus_tag="KB913_001651"
     CDS             complement(11473..12156)
                     /locus_tag="KB913_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBB6820015.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12174..12791)
                     /locus_tag="KB913_001652"
     CDS             complement(12174..12791)
                     /locus_tag="KB913_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBB6820016.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12801..13625)
                     /locus_tag="KB913_001653"
     CDS             complement(12801..13625)
                     /locus_tag="KB913_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBB6820017.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13618..14178)
                     /locus_tag="KB913_001654"
     CDS             complement(13618..14178)
                     /locus_tag="KB913_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820018.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14352..15308
                     /locus_tag="KB913_001655"
     CDS             14352..15308
                     /locus_tag="KB913_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6820019.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15613..16569)
                     /locus_tag="KB913_001656"
     CDS             complement(15613..16569)
                     /locus_tag="KB913_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBB6820020.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16673..17275
                     /locus_tag="KB913_001657"
     CDS             16673..17275
                     /locus_tag="KB913_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6820021.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17363..18862)
                     /locus_tag="KB913_001658"
     CDS             complement(17363..18862)
                     /locus_tag="KB913_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBB6820022.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18878..19402)
                     /locus_tag="KB913_001659"
     CDS             complement(18878..19402)
                     /locus_tag="KB913_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBB6820023.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19700..20449
                     /locus_tag="KB913_001660"
     CDS             19700..20449
                     /locus_tag="KB913_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6820024.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20440..21225
                     /locus_tag="KB913_001661"
     CDS             20440..21225
                     /locus_tag="KB913_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBB6820025.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21194..21910
                     /locus_tag="KB913_001662"
     CDS             21194..21910
                     /locus_tag="KB913_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6820026.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22012..23046)
                     /locus_tag="KB913_001663"
     CDS             complement(22012..23046)
                     /locus_tag="KB913_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBB6820027.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23050..24108)
                     /locus_tag="KB913_001664"
     CDS             complement(23050..24108)
                     /locus_tag="KB913_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBB6820028.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7188 a         5222 c         4225 g         7624 t
ORIGIN      
        1 ttttgctatt ctattttaat tgaattttgc aactcactct tctttattcc aaacctactc
       61 gtttgaatat cacgtcaacg tttttcaaat gatgatgata atcaaaggca tcgtctattt
      121 cttctttaga taataccgat gtgatggttg gatcttcttc taacagcggg cggaactgca
      181 cttggttgtc ccaagcgtac gcagtttttg gctgaacaag atcataagct tcttctcttg
      241 tcattccctt atcgatcaat ttcagcataa cgcgctggct ataaatcaaa ccaaatgttg
      301 cagacatatt ccgcttcatg ttttcaggaa agaccgttag atttttaacg atattgccaa
      361 aacgatttaa catgtaattc aataaaatcg tggtatcagg caagatgatt cgttctgctg
      421 aagaatgaga aatatctctt tcatgccata atgtgacatt ttcataggca gtgaccatgt
      481 gtccgcgcac cactctggct agaccagcca tattttctga accgatcgga ttccttttgt
      541 gcggcatagc agaagaacct ttttgacctt tcgcaaaaaa ttcttctact tcacgtgttt
      601 cggatttttg caatccgcgt atctctgttg caaaacgttc aatacttgta gcaataagcg
      661 ccatcgctga gaaatattca gcatgtagat cccgagggag aacttgagta gagatttctt
      721 gtggacggat ccccaattgt ttacatacat actcttcaat aaatggcggg atatttgcga
      781 acgttcccac tgctcctgag atttttcctg cttctactcc ttttgccgca tgttcaaatc
      841 gttcgatgtt ccgtttcatt tctgaatacc atgtggcaag tttcaatcca aaagtagttg
      901 gttcagcatg gacaccgtgt gtccgaccca tcatcactgt atatttgtgt tcttttgctt
      961 tttcgccaat gatttccgta aaacgtttca agtcttcccg taaaatatca tttgcttgct
     1021 tgatgagata gccataagca gtatctacga catccgtact tgttagacca taatggaccc
     1081 attttctttc ttctcccaat gtttcagaaa ccgctcgtgt aaacgcaacg acatcatggc
     1141 gtgttaattt ttcgatttcc aagatccgat cgatatcaaa tgatgcatgc tcacgaattt
     1201 ttttcacatc ttcttgcggg atttcaccaa gttctgccca agcttcatct gctaaaatct
     1261 cgacttcgag ccacgcacgg tatttgttct cttccgtcca gatattcccc atttcagggc
     1321 gtgtataacg ttctaacatg ttttttctcc tctaatccca aatattcgtt tgtttgattt
     1381 cttccagcgt ttgctggatg tcttctgtca agatagtgat atgtcccatc ttgcgacctt
     1441 tttttgcttg tttttttcca tagaaatgga attgccagtc tggcttattc tcaatcaagc
     1501 gatagctttc cagcagttgt tctcccaaaa cattgaccat tactgcattg cttatcaaac
     1561 gtactttttc tcctaatggc caaccacaaa tacctcgaat atgggcatcg aactgactca
     1621 tagaacaagc ttcaatagaa taatgtccag aattgtgagg acgaggagct aattcattca
     1681 catatagccc gcctgttttt gttaaaaaca tttctacccc taaaacacct gaaaggctca
     1741 ctgcttctgc aatcacacgg gcaatacgct cagcctcctc gatcacatcc tgatcaatcg
     1801 cggctggagc aatcgtttca tgaagaatat tgttgtggtg gatgttttcc acgaccggaa
     1861 aagtcgtgaa atctccttga ccatttcctg ccaccatgat cgaaatctct ttttcaaacg
     1921 ggatccatgc ttctaaaaca caggttcctt ctcttaaaag gtccatggca ggagctagat
     1981 ccgcccgact tttcaaaaca tactgcccct tgccatcata gccgcctcga gtggttttca
     2041 aaacacaagg atagccgatc ccgtcaatcg catcttggat atccgtcgga ctgacgatcg
     2101 ttgcataagg agcaatcacg atgttattcg tttccaaaaa agatttttct aacaggcggt
     2161 cttgcgtaat cgcaagcaag tctgtccctt gaggaataaa tgacatgggt aaaatcgcat
     2221 ttaacgcctc tacactgacg ttttcgaatt cataggtaat gacatctgtt cttctggcaa
     2281 gctctttcag cgcaaaggtg tcatcataga cactttcaat gtgccaatct gcaacttgtg
     2341 cggctggaca atcgctcaca ggatccagca cacctacttt aaagcccatt tcttttgcac
     2401 taatcgccat catacgacct aattgaccgc caccgacgat cccgatcgtt gaaccaggca
     2461 acaaaggttt aaccaagttg atcactactt tctataacag ttttagccaa cattgaacgt
     2521 ctttcagcca atttagcctc caattctaaa tcatacatgg aaagcatctg tatcgcaagt
     2581 agtccagcat taattgctcc cgcttttccg attgctgtag tagctacagg tactcctcca
     2641 ggcatttgga caatcgaaag aagcgaatcc aaaccattta atgttcgtga ttggaccggt
     2701 acaccgataa ccggcaaagt tgtttttgat gcgaccatac ccggcagatg cgcggctccc
     2761 cctgctcctg caataatgat tttgattcct ttttttcgag cgttttgtgc atattcaaac
     2821 atcaaatctg gggttcgatg agcagaaacg accttttttt cataagacac accgaattca
     2881 tccaatattt gacatgcttc tttcattgtt tcccaatctg aagtactccc cataatcaca
     2941 gagatttttg ctgtcattgt ttttcctccc agtttttcta cattcatatt ttaacaatca
     3001 ctttttttga tgtcaaagaa atttcgaatg ttaacaaaga aaaacatttt attgttcgtg
     3061 tttattaaag ataaaaaaaa ggaatgtgac aaaagttagg tcacattcct ttttatggat
     3121 aaacggtgtt ctcctgccaa ctcctcggtc acaaggaaca atattcaaca aacatgagaa
     3181 gctttttttt gaaattgttc cttgtgactc ggagatgaac ggcaggctca cgacctcttc
     3241 cttcaacggt gttcaatcag ctgaccctcg gtattagctc aaacaaacgg caaaatacga
     3301 ggaactattt ttccgtttgt ttctctaaca atcaggtcaa aacgctgatt tcacaacctt
     3361 tcttttgctc tattacttct tgaaggcttc ttccaatatt tcttcatctt ttttcaatcc
     3421 attaaagatc aaattcaata tgatagccgt aatgctactc attacgatgc catttccagt
     3481 gaacatttgc aatgtttgcg gcatttgact gaataatgtc ggcgtaacat tgaaacccag
     3541 cccaaatcca acagaaacag caacaatcaa tagattttta tcattgctga aatcaacttc
     3601 caacagcata cggattcctt ggactgccac catcccgaac atgactaaca ttcctccacc
     3661 aagtaccggc tcagggatga tttgtgctaa cgcaccgatt ttagggaata atcctaaaac
     3721 aatcaagaag aatgcagaga aatagatggg ttttcttgtt ttgattcccg aaagttgaac
     3781 caatccgaca ttttgagaaa agccagtata agggaatgta ttgaaaatac cgcctaagat
     3841 aacggcaagt ccttctgcac gatatccctt tttcaattct tcttctccaa catttttccc
     3901 agtaatgtca ccaagtgcaa aatatacacc tgttgattct accatgctga ccatggaaat
     3961 gatgatcatt agtaaaatcg accatacgtc gaaagttggt ttaccaaaat aaaagggttg
     4021 tggaacatgg aacaacggcg catctccaat cgcgctcaga tcaatcattc ccatgaaagc
     4081 agctaagatg cttcctccga ctaaaccaat caataccgcg attgaacgaa tgaacccttt
     4141 tgccagcatt tgcacgccta caattaggag aatcgtcaca aatgcaagta gcagatttgt
     4201 tttgtcacca aaatcagctg ctgttgcatt acctccaccc attttctcga ttgctacagg
     4261 aatcaaagtc aaaccaataa cggtgataac cgttcctgtt actataggag ggaatagttt
     4321 tttaatttta gaaaagacac cagaaactaa cacaacaaag atcccagaag cgataataga
     4381 tccgtagata gctcctactc cttcattggt tccgatcaag atcagtggag ctactgcttg
     4441 gatcgcacat cctaaaacga caggcaagcc aattccgaaa aatcggttaa ctgtcaattg
     4501 caataatgtc gctaatccac acataaagat atcaattgaa atcaaataag tcatctgttc
     4561 ttgattaaag cctagtcctg taccgatcaa aagaggcacc gctactgctc ctgcatacat
     4621 cgctagcaga tgctgcagcc ctaaaaccgc agcttttcca ttttgtgttt ctttttccac
     4681 gattatgcgt cctcctcaag aaactcaact tgtccattcg tcaaggaagc aatacgcgca
     4741 agagaaacga ctctcaatcc catttcttca agtaactgac gtccatcttg gaaagacttt
     4801 tcgatgacga tcccgattcc ttctacttgc gctccagctt gctggcataa ttcgatcaat
     4861 ccttttgccg cttgtccgtt tgccaagaaa tcgtcgataa tcaatacttt gtcttctgaa
     4921 gataaaaatt tacgagaaat agaaatcgta cttgtcactt gtttcgtaaa agaataaaca
     4981 gaagctgtca ataattcttc atccatcgtc aaactttttg cttttctagc gaagatcatt
     5041 ggaacatcta attctcttgc agcaaataaa gctggtgcga tcccagaagc ttcaatggtc
     5101 acaactttcg tgattccttg ttctttaaat acttctgcaa accgttttcc catttgttcc
     5161 atcaatacag ggtctacttg gtgagtgacg aagctgtcga cttttaatac gccctcgcct
     5221 aatatacgtc cgtctttttg aatacgttca actaattctt tcactttatt tgctccttta
     5281 tcatttatta ataccgaaat aaccgctttt gtgcaaaaac ctactatgtt tctgttaaag
     5341 aaaaacaccc tccactttat cataagaaaa gaagggtgaa atagccaatc ttttacttat
     5401 agtccagcat ttacggtact ggctagaaac tgtcatccat attatgacga tatataagta
     5461 ggtatgtaaa actaataata gtgtaaattc attttcttgc aactgttttg cacgtgaagg
     5521 cagtttgcca tatttgaata aaaaatgttg tttcaaatat tgaaaacagt ctaacactac
     5581 tttctgaaac tgacaacgtg gtttacttat ttttttgtaa aatctaatga tttttaatgc
     5641 attattcctt tttgttcggg tttaaatagt tatttttatt ttctcctatc taaaaaagca
     5701 gcccacataa aaagaaggca tgacaaaaag catgtcatag cccctttttc cgaataaata
     5761 gtgttcaaaa gacagcctat cggcaataag gcaagatttt ataaactacg ggaagtaatt
     5821 tccgtaaatc tattcttatt cttttaagct gacaagctcg tcaatcacta ctgcttttcc
     5881 tgaagcaata gaatgatttg ctgcgattcc tgtcaaaatc gacaaaatac catctacgtg
     5941 agttgctgcc cgattccacg gatcttcttc tttttcttca ccaaatagat catctaataa
     6001 acgcggatct cctccgccat gtccgcccgc ttcttgttcg acgattacct catatggctc
     6061 accgaacatc ggatagacat ggatggactg aagaacggct gctccttcat cctttttatc
     6121 tccacctgca ttgatgtaag acttttcgat cactttcatt tcgatccgtc ctttgctgcc
     6181 attgaaagaa acattgaatc cttcccacgg catatacgcg tttagcgaat acgtcaaaat
     6241 cgcaccagtt tcatatttga ccgttacgcc tagtgtatct tcaatagaga tatcatcgga
     6301 aaatacactg cggtcacgaa tatatccact gtctttttct gcttctaaat acatttctcg
     6361 caattcctca ttggctgaca ggtctatagc aaatggatca gctttagcta gttcgcttcc
     6421 atagcatcga ctgtaaaata tttctactcc gcgtttctcc gcattatgca tcccataaaa
     6481 gtttaatcca ccgaatgcaa ataccttttg gggacggctg ttcaaccaaa aattcactag
     6541 atcaaaatga tgggtagatt tatgaacaag aagcccgccg ctattgtgct tatttcgatg
     6601 ccatcttctg aaataatctg ccccgtgttg cgtatttaac agccattcga agtggataga
     6661 aaacacatca ccaatcacat cactttctat cagttccttt atcttcgtgt gatacggtgc
     6721 ataacgataa ttaaaagtga ctcgcaggct tcttcccgtc tgtttttgga ccgttattat
     6781 ttcttgagct ttttcctcat cgatagtcag aggtttttcg caaataacat catatccttt
     6841 tttcattgca cgaatgatat aatcatgatg cgttcgatct actgacgtaa taatgacttc
     6901 agccggccgt acgtcatcca gtagttgctc aaattgtgat ggcatacatg tctttacttt
     6961 tttctgtcca tacttgttca caagtatccg atttgcataa tccatccttg tttgagatac
     7021 atcacaaaaa ccgactagtt cacaagtttg atgatacgta gaggcaattg cctcataaaa
     7081 aaaacgcgct ctcccaccaa gtccgacttg tacatatttt ttcttcattt aaagtcattc
     7141 tccttttctt ttaagcaaaa tactgtgaca aatggcagcc ctggatacag taatgcagtg
     7201 agtaaaaaat catgctgtat acaccagaac agtccataca aaaggcataa ataccacaga
     7261 aaccccttga cgttttttga caacagccag atattccttt tgatcaaata aacaagacta
     7321 tctgctttat cttctttgca gatatcaatt agcgtactaa aaaaactatg ggatacaaaa
     7381 agcaacagac acaatagaaa aggaatcaga taccaagctc caatctttcc cactaataaa
     7441 taccaatcaa ctgcaaaaat aatgacaaac agctgaaaca acgtaatgat gaaacacatc
     7501 cgtttgattt ttcctttcct ccaacatacc tttttttctg ccaagtaatg gacagataga
     7561 taataagaag gatacatcat caaaaaataa atcagataga caacacgagc agacagcact
     7621 aatcctaaag tgaacaaaca tcctagaact aaagcgaaaa gagcattact gataagactg
     7681 gttaaaaaaa tccgacagac atagtagttg agcttgtaaa gaaacatctc ttctattggc
     7741 tttttcatat tcagcccttc agaccgcttg tactgatccc ctggacaaga tatttattga
     7801 agaataagaa aatcagaaaa accggtagca gcgacaacgt agacatcgca aacatactcg
     7861 cgtaagtcgt actagatcca gcgtctgcaa ataatttgat ggcaatcgat accgtgtaag
     7921 atctcggctt gtttaaataa atcaatggtc ccatgaagtc gtcccatttc caataaaact
     7981 ggatgatgat cgtcgtgatg atcgaaggtt tcagcaaagg aaaaataatt ttggtaaaga
     8041 cactatactt gctgcatccg tcaataatcg ctgattcatc taactctttg gggatgctga
     8101 ccatgaattg catgatctgg taaatgaaaa atgcttgtcc aaaaaaatgt ggtaaaatca
     8161 gcggcacata cgtcccaacc aaattcagcc gattgtaaat aataaactgc ggaatcaaaa
     8221 tcacttgtgc aggaatcatc atcgttacta acatgacgac gaaccagaat ctttttcctt
     8281 tgaaatcgat tctcgataat gcgtaagcaa tacaagtcga gctcagaact gtccctatcg
     8341 tcgaaactgc agagatgaca aacgaattcc taaagaaagt aaaaaatgaa attccagcaa
     8401 accccgccca tccttttgcg taattttccc attgaaaagt ctctggaatc aaattcagcg
     8461 aaccactcat aatctcttga tccgttttaa aagaacctgc gatcatccat aagaccggat
     8521 aaatcatgac tagacctaat agcaaaataa aaccgtattg aaaccatttc gttactgtat
     8581 tattcatttc ttcctcctct cattcacaca acgacccatt tttttgatga tttgaaaatc
     8641 agaaaggtga cagctcccat aatcaacagc atgatccacg aaatagcact agcatacccc
     8701 atagaattaa aagaaaaagc ttggttatac acataaagag cataaaagtt cgtggcatca
     8761 ttcggaccac cttgggtaat gataaatgcc tgcgtaaaag tcataaacgc cgcgattgtc
     8821 tgcataacca agttatacaa aatgatcggc gaaagaagag gtaacgtgat cttgtaaaac
     8881 gtctgccatt tgttcgctcc atcgatctct gccgcttcat aatacgagcc tgggatctct
     8941 ttgatacctg cagcaaagat gatcattgcc gaaccgaatt gccaagcaga catcaaaaca
     9001 agagggatca tgaccagttt ttgatcgcta aaccaggaaa gcgcaggtgc gcctaatcgt
     9061 tccaggaaaa tattcactaa cccgttttta gaaaacaact cccgccaaac tagagcgata
     9121 gaaatactgc caccgatcaa actaggcaca taatacaaag aacgaaagaa agtcgttcct
     9181 ttgatattcc tcgttaaaag ataagcaatc aatagaccaa agatcagttt cacaggtaca
     9241 gatgcaaata catagagaaa agtgactcgg atggagttca aaaaacgggc atcactcagc
     9301 atctttatat aattatccaa gccgatccat gagactggat ttcccaaacg ataatcggtg
     9361 aacgaataat aaagtgacaa gatcatcggt atcactgtta tcaatagaaa tcctaggatg
     9421 aatggagaag caaatacgta accgaccaca ttgtcttgat ccaagaaccg ttttagtttt
     9481 tcttttttca tgccttcctc ctgctgctat cctagaatgt ttgacgcaaa ctcataaaga
     9541 ctctctgctg cttcttctgc tgttacttct tcataaatga ctttttcaac taaaagattg
     9601 tattggtctt gaatttccgg attcaaagca ctatcaaaga cattcacttc gccgttgtcc
     9661 atatcggaaa tcatttctaa ataatcaaat gtcgcttgca aagttgcatc atctgcacga
     9721 gcgagctgtt ctcgaatatt cgacatgatt ggtacaccac gttctccttt taaaatttca
     9781 ttggcttctt cactgttttg aaagaaatca ataaacttag cagcttcttc tttatgggct
     9841 gagctttttg ccatactcag catttgcgaa gaacgtaaag ggataccaga ttctccatct
     9901 gcttttctgc gaggtggatt aatcaactga atctccatat cttcaggagc ccctgacaat
     9961 atttctgtca actggttact tgatagaaac accattgccg cttctctatc cctaaccgcc
    10021 tgaaaagaca gatccgtcgt acttgcagct ccaccacctg gttctggatg ggcccctttg
    10081 tctaccagat ttttacgcag ctggaaaaaa tctgttagat agtctggatt ttcaaatccc
    10141 aagctgttag atagatcttc ccgattataa aaattcaatc ctttctcaac ttgtggtatt
    10201 tgaataatac agccagctat aaaatcttcg aatcttgaaa tagcatagat tcctaattct
    10261 tcagtgattt gatagctgat ttgttcaaat tcatcccatg tccaatttga agctggttca
    10321 gggatattta attgttcaaa tatattttta ttgtaagcaa tcgcaaacga attcaccccg
    10381 ttagacagtc caactaattg cccgtcgtaa gtcgtcgttg ctaaatagga ttcatctgca
    10441 ttagaaatat caattatccc ttgctccaca tattcatcta atggttcaat ctgattgatg
    10501 tattgaggaa attgattgtt cagttggaaa atgtcccaga tatcatctga tgctgctagt
    10561 gtacctaatt ttgtgtaata tccttcataa tcataaaatt cataatcgat cgtcacatgg
    10621 ggattttttt cttcataaag ctcgattact tttactgttg catcgtgtcg gacttgcgaa
    10681 ccccaccaag ccatgttcag cgtgattttt ttgtcatctt cttgcccaca agccgtcaag
    10741 aagaataaca taacacttaa agctaagatg attctcattc ttttcttcat tctctgcacc
    10801 tctacttcca ttgttatttt tcaatatact gtatttttat acagaacata tttattaaac
    10861 gatctttttc aaggggaata aaaaccaaga cttgccttat cgttctgcct aggatgaaca
    10921 actcaatact ttcaagaaaa attagatagt gctgattctt ctttcatcgc taaaaacact
    10981 tcttgcttca atgatgggag gataattacg caaagaaaaa aggatatcag acaactgccc
    11041 aatatccttg acatagctaa ataagcatgc ttcttcgtgt gcgctcttcc ctaaaaaaca
    11101 gaaaaataac tagtaattct gtatgaaatt aggtacaata tacacgtcga tgcacaagca
    11161 ttgactatgg caacttgatt ggtcagttcc cgctgacttt tcaagccccg acaatttagc
    11221 tgctactaaa ttgtcgggtg ccttttttag tttttattcg tttttcattc tatagaaagc
    11281 gcttcaataa atcaagacat ttttttgtta gaatgctaat aataacaaaa ggttttaact
    11341 cttcttatgt acattacagg taaaaaaaca aaaaaatttc tctttttttt gaattctgaa
    11401 caaatagtac tggagtacaa aagacgagga agagccacta tctgctcttc ctcgtctttt
    11461 gattctcacc tgttattcat gattcttttt ctcagtttcc cgatattttt ccattttacg
    11521 actaaaaagc tctccgctac ttggtggcgt atatgtgatg gcatttgctc ctgcttgaat
    11581 ggtctcagca atactttctt ccgttggacc acctgtcgca atgataggaa gttcaggata
    11641 ttttttacga aaatggcgta ctgcttctgc agtttcttta cctgcactga tattgataat
    11701 cgaaatacca gctgctaact tttcatctat ttctgtatat ttcgacgtta ccgtactgat
    11761 aactggaata tcaactactc gacaaacttc ttttactgtc tctaaaggcg taggaccgtt
    11821 caaaacgacc cctaacgaac cttgcgcttc tgcgaacatg ctcatgtagg aagaacgagc
    11881 accttgtgtc aaaccaccac ctacaccgga gaaaactgga atgtcagctg cctcaataat
    11941 gcttttagta atcgctggat gaggtgtaaa aggatacaca gcaattactg cattcgcatt
    12001 tgtattacgt atgatcgcaa tatccgtagt aaagatgatc gaacggatca attttccaaa
    12061 tatcttgatc ccgcttgctt ctaaaatgat ttccggtact cttacgatat cttttctcaa
    12121 ttccgtcatg atttctggcg taaattgttc tgccatcagc cacttctcct ttgctatctc
    12181 cggtcatact gattcaattg atacgtctcg atgacctgga tgattttttg cgcataaccg
    12241 gggtctgtcg cataacctgc atcttgcaat gcttgtgcgg cttcctgata gttggtggcc
    12301 gtaatcactt tttcatacag cgcaggattc caatctactc cttggacgaa cagttgtgta
    12361 tggtcatcca tggactgttc ccatgaatca tacactttga agtctccttg gatagttatc
    12421 cattcttcgt taacaaattc ctttgtttcc aggcttactt tcttctgatc cccataagcc
    12481 ttgatcccga aaagattatt gtatttgcta gccaaggtac tttttcccca atttgattct
    12541 aatatagctt gtcctaaaat gatactagga agcactccat aaccatcttg tagttcttgg
    12601 gcatgcggaa caagccgttc aataaattgc tgatgggatt gcgcttcatt ttcttgctga
    12661 ttatcagtaa aaggagaaga cagattcttc aaggaaaaaa caaaggctaa gagtatcact
    12721 gctacaccgg caaccactgc tggccaacgg atattcttgc gcttttgctt tttccacttt
    12781 tttttcgcca tgatcaattc ctacttttca tttaattcat tcagatattc ttctagcgtc
    12841 aattggtgtt tggtgatata ctcagcgttt tctttaccga cataacgtaa gtgccaaggt
    12901 tcatatgtga tcttagttat atcttcgtgt ccttttggat aacgaacgat aaatccatac
    12961 tgcgcagcat tatctgcgat ccatttagct ccaggctgat ctccgtaact tgcatccaat
    13021 acagtagaag gataactgtt gtaccagttt tgatcgacga catcgactgc cagacctgtg
    13081 tggtgttcgc tgtatcctgg ctccgtaatc gtttctttag taatctttgt cgcctcctct
    13141 tctgatacac cttgacgact catcacatct tggacatttt gttcgaaaac ttgttgttgg
    13201 gatgatacag accggtaagc tgagaccatc actaatggaa atccagctgc ttcagcagcc
    13261 ttggcaaatg cttcatattc tggagcaatg cgtttgtcga tcaagtatcc gttacttaat
    13321 gatgccaatt gagtagactc atcaatttct ttttctaatt tgtgatctgg accaaccaaa
    13381 actagcttcc aatcgtctgt tttaacatct ggcaattgtt tggacgtacg atcttttgtt
    13441 tctttgtcct ttaccttgct gctggttgtt tgactgttct tttctttact agcagttgtt
    13501 ttggtgcttg ttcgttcgac tgcttgattg ccggcttgaa catgcgaatc atcatcgcta
    13561 aaaataacat agcccattgc tgcgatcata atcacaactg ctccaaatcc taaaaattta
    13621 ttcacttgaa aaatcctttc gttgttcttc acgttcccca ttcgcctcat gaacgtaagt
    13681 ttcttccaga ttttcattca cccaatcgag aagttcgatt ttttctcctt cgatctgttt
    13741 ttgaacatct gctggcagac gaaaattcaa aatatcatca tagccccatt catcatattg
    13801 aatacttact ttcaagtcaa ggtatctacc agcctgctga ttatttttca aagggatcag
    13861 ctcgactttt gctgctttgc tgctaagcca tttttgcgcg atgcgtgttt tgatttgctt
    13921 gtactctgca acggcaacgt ttcgtttttc gggaaaaata atcgtttgac gcaaaatctt
    13981 ttgcgttagc atccattcat aatcagtgaa aagatttttt actttctgca tcgcttcaga
    14041 tggcagattt ttctcgccat ctttccattt ttgccattgt tctggactga tcagcaagta
    14101 ttcatctaaa aaattttttt cagtttcaaa ctgttctaat aatacactca taataagatc
    14161 aatatatact tgatgcacgt ttatcccctc cttttaacta ttctacttaa gttttgatca
    14221 aaaagcacct cttaaatcgc tgctttcatt ttttttaatg tttcaagtcc tctcctcttt
    14281 attcttcgtg atttttgtta taataataga cagacaagaa actcaatcca actatgaagg
    14341 agcgttttca gatgaaaaaa tatcaatggg gaatcgttgg tcttggtacc atcgcacatg
    14401 agtttgccga aagcttcaat caagagacga gcgaactaac agcagttgct tccagaactt
    14461 cagaaaaagc ggaaaacttc gctcaccgtt acaatattcc aaaagcttac ggaagctatc
    14521 aagaaatgtt agacgatgct gaaatcgaca tcgtgtacat tgctgtacca aatagacagc
    14581 atatcgacca tatcttggca gcattggaag caggcaaaca cgttctatgt gaaaaagcca
    14641 tcacgatgaa taaaaaagaa ctggctgacg ctatgcgctt agcagaagaa aagaatttga
    14701 tcttagcaga agcgatgaca atcttcaaca tgccacttta tcagcagtta cgctcaataa
    14761 tggatacagg aaaactgggg gctttaaaaa tgatccaagc acctttcggc agttacaaag
    14821 aaccagaccc taaaaaccgg ttcttcaatc cagaattagc tggaggagct ctgttggata
    14881 tcggtacgta tgctgtatct ttcgctcgtt tctttttgag ctctcaacct gaagtagttg
    14941 cctctacaat ggttcctttt gaaacaggcg tggacgaaca atccgtcact atcttgcgta
    15001 acaaagaaaa tgaacttgct gctgtcagct tgacttttca ggcaaaaatg ccaaaagtcg
    15061 gtatcgttgc ctttgagaac ggttatgtga cgattgctga ttacccgcgt gctgatcgtg
    15121 cggagatctt atttacagat ggtacaaagg aattcatcga aagcgggaat acatctgaag
    15181 caatgaatta cgaaataaag aatatggtac acatgattga aggtgacttg cccaatcgct
    15241 ctctcttctt gacaaaagat gtcatcgaaa tcttggatca aatgcaagtt ctatggaaaa
    15301 atatgtaatt ttaaaaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    15361 acaaaaatag ctcctcctat ttttcgtttg gctggactta ttaccgcaga ggaaagcttt
    15421 tgaacaccgt ttaagaaaga ggttgtgagc ctaccgttca gctccgagtc acaaggagca
    15481 atttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg aggagttgac
    15541 aggagaacac cgtttaaaga agaggttgtg aaatcagctt tttgacctga atattagctg
    15601 aattcacaac ctctattttt ggattttttg ttgggagaat tctgccttga tttcaataaa
    15661 acttttaaaa gactgcaaaa actggaacaa ttctgctcga tcctcgaatt cagggcgact
    15721 agtcggcaga ggcatttgcc gatacaatac ataaacttct tcaatacgtg ttaaaatttg
    15781 tctgccatca tttgactctg aaaatgtttc tgcagtataa atcaataaac catagatatg
    15841 ttttccataa taagctggtt gctggattct ctctagattt tccagcatgt ctttaatcac
    15901 attggcctgt gctcttctca tagagaagta agtttcgtag tatagcggct gtctgagcca
    15961 gtagttttct tgatgttctc tggcatcttc ttggctttcg cgaatgaatg tcagtaaatg
    16021 ttcgcatttg atctgcacat cttctttatt ttctgataaa agaaattctg ccatttgtct
    16081 caaaatattt cgaaattctt tttcgatctg tatttggttt tccttcagct gcttcgtacg
    16141 atctggcatg taaacatttg caagcaaagc aaatactaat ccaatcgcca ttaatcccgc
    16201 ttcattgccg atcagctgcc aagacatgtt ttcctccact aaataatgag tgaccaaaac
    16261 cgaatttact actatccctt cggttaattt gaagcgagag gcaagcggga tgaacaggaa
    16321 taaaaaaaga ctgaagccaa aaatagtata cccaacagca aaaaaactga acagtgctgt
    16381 tgccgtagct aatataaagg ctgcgattcg attcatgccc gtacgcaatg tagagcgctt
    16441 ggtatttcct acacttaata atgcaatgat ccctgcagct ggccaataca acagcgataa
    16501 gctacccgct gtgaccatcg aaaagaagac actgatcact gttttgactg ttcgcattcc
    16561 tatacgcatt tacttccccc ttttttattt taattatact tgaataatga aaaactagct
    16621 atcagacaaa agtttaggta tgatagtaaa aagaccaaaa aggagaatct ctatgcaatt
    16681 tggccgtttt cgactaggta tgcgtacgat caaaagtgcc ttagctgttt ttttatgtat
    16741 cttgtttttt catttgactc aacgaggaat cccgatgatt gctgcattat ctgctgtttt
    16801 ttctttgcgt caggacttga ctacaaccgt ttcttttgga aagtctagga tcatcggcaa
    16861 tacattaggt ggtacattag ctatcattta tttttttgtc aaaagctatt ttcacaatga
    16921 ttttttggta gaattgatct tgcttcctat tctagttatt attgtgatcg tcgtgtcaga
    16981 tggtattaac aataattccg gtatcatttc cgcaatagct acgttgttgc tgattgcgtt
    17041 gagcatccct caaggcgaat ccgctttgta tgctatccaa cgtgtactag atacttttat
    17101 agggacattc attgcaatcg gtatcaattt ctttcttcgt cctcctgaaa cagaaaagaa
    17161 ggaagaacta tcagaagatt tggtcgaact ccaaaagaaa gaacgattgc taagaacaaa
    17221 tttacaagag atagaagcta agatccaaaa acaaaagaaa aatagcgagg actaattttc
    17281 ttttgcaata aaataaaaaa atggagagaa gaactttaaa aagtcttcct ccatttttga
    17341 ttgaacggtg aagtgtacta ctttattctt ccttcatcga gttttgttct gcctcttttg
    17401 gcgcttcata catatttact tggctagtag tcccacgtgt cgacaaattc tctacgattt
    17461 ccttcaagtc aagtcctgtt gtcgctttta gtgtttcttg agtagaagaa agcaaatttg
    17521 tggcataatt tgtcactcgg ttcgctccac tggtttctcc tgaactgctt cctgtatcga
    17581 caacagagat tttttcgata tttcctagcg gctgtgctgc ttcgcgcatc aattgcggta
    17641 gcatatcgat aaccatactc aagacagctg cttcgccata ttccttgaag gcattggcga
    17701 tcttttgttt tgcttcggct tctgcttttc cttttgctag tgctgcttcg gcttctgctt
    17761 gtccagctaa acgtgtctta ttggcttccg cttctgccag tgcttccaca cggaatcgtt
    17821 ctgcttcggc ttcagtcact tctttgactt tttgagcttg tgcttcttgt tctttagcgt
    17881 accgatcggc atctgctttt ttcttcactt ccgaatcata ttgcttttca cgacgtgtga
    17941 tttctttttc ttccagttcg atttgttttt gacgttctac gattttaatc tgcatttcct
    18001 gttcgattac ttgttgttgt gctcgggcac tttctaaatt gtaggcttgg tctgcttttg
    18061 ctttagcaac atcttgttct tgtttgtagg ttgctaattt cagttctttt tcttttaatg
    18121 attctgcgat ctctgtttgt cgctgtaatt cagctgcttg tgattctttt tctgcttgag
    18181 cttttttgat acgcgtttct tttagagctt ccgcttctgc tatatctgca tctcttttga
    18241 cttgggcgat tcttggtttc cctaaagagt caagataacc gtttttgtct ctgacctctt
    18301 tgatagtgaa agaaacgatg atcaacccca tttttgcaag gtctacagaa gcgacttctt
    18361 gtacgctttg actgaactta tcgcgatttt gatagatttc ttctacagtc atagaaccaa
    18421 gaatcgagcg caagtgtcct tctaatactt ctcttgcttc attttccagt tcttctcttg
    18481 tcttgcctaa aaactgttct gctgctgtag caatctcttc tacagatgaa ccgattttga
    18541 tgatcgaagt accatcacac atcaccggta cgccttgttc cgtatacact tcaggggtgg
    18601 agacgtccaa tttactcgat aatagactga tccgattcga acgttgaaaa actggcaaga
    18661 cgaatgcgcc acctccacgc acaattttga ttttgttatt gctttcatca atgtgcacat
    18721 ttttgcttcc taaataactt ccactgatga tcaacgcttc atccggtttt gctgtctggt
    18781 acttcgctac aaagacgatc agcaacatca gtaaaatcaa agctgcgatt gcgatcgcga
    18841 taaaaacaac tggtatttcc atttaacaca cgctccttta agcttttatc atgctttcat
    18901 aaggcatgac ataacagatt ctttccttga tctcaatgat caatactttc gttccccgct
    18961 cagctgtctg ttcttggggg ctgtaaaaac aagctggacg actaatggaa ccggtaacac
    19021 ttttcaactg aatttctccc atacctcgta cagggatcgg tgtgatcaca acagctactt
    19081 gtccttccag agttttttca gaagacgaca tcgttgattc ggcatgtttc atcggcatca
    19141 atatatagaa attaagcaaa aataccaaca ctatcgatat gcctccacta gcaataaata
    19201 aaaataaaga tgattgatct gttaaacgct cacctagaaa accaaataag cttgtgaaag
    19261 ttaaccaagg gataataagc atcggatcaa gcgggccatc aaaatcgaat acatctccaa
    19321 aaataatcaa taggactgcc aatcctgcac aaatcagcaa tgtataccaa taaatcgtct
    19381 caagtgcgat tccccctatc atatacacgc ctccttccat ttctacgtct atcataccaa
    19441 tgtttgaaaa ttctgtatag cttcttttac cgactcagtg gtgtttttta taggaaggtt
    19501 gtgtttatcg ttgacaattt gttaaatttt tgttttcatg ttaaaatttt cacaataaat
    19561 tctttcgagg tagcctatgt ttcctttttt taagaaaaaa ccattaaagc tccagaacac
    19621 gatcatcctt gtcgtttgtt tctccacatt cgtttctttg attgtttctg ccatattgat
    19681 caggaatttt attctttcga tgaaccgatc tagtgtgtca gataaaatct ctagcattgc
    19741 taaaatcgtt gccaatgata aactcatcca aaaaaagctg cagactggtg acccgacaca
    19801 tgcgattcaa ggaataacaa atgaaatcat gattgcatcg aatttagatt ttatcgttgt
    19861 catggaccct gaaggcattc gatattctca cgcagaccca agttacatcg gtcttccttt
    19921 ctcaagtcat gaagatgtga aaaaagtgat tggaggacaa gaatttttct ctgaaaaaga
    19981 aggaatgtta gggttcggct tccgctattt cgtccctatt tattatgatc aagagattat
    20041 tggtgcagtt tgtgttggct taacaaacaa cacgattgac aatcaagtca aagatggaca
    20101 aaaaatgatt gttttttcat tgattattgg acttagcgta ggcatcatag gcgccgtttt
    20161 tcttgcccaa aaaatgaaaa aagtactgct tggacttgaa ccacaagaaa tagcagaaca
    20221 gttaagtgaa aaaacgatta tcgaaaatga agtagatgaa ggaatcttag ccatctcttc
    20281 tgataaaact atcctcttga tcaatacacc tgcaaaaaac attttctacc aaacagagca
    20341 gctattggat ttcgaagtag gaaaaaaatc agtgataatc tatatgacgt tttgtttaaa
    20401 gagacgattg agcatcaaac gaccgttcgg actcaatcca tgtatttaaa tgggatagaa
    20461 actatttcta gcgttacacc tctttttagc aatgaccgtt ttttaggagc agtcgcaact
    20521 ttacgaaatc gatcagaagt aatgaaatta atggaggagc ttggggggac gaaacaatat
    20581 ataaactcca tgagagctca aacccatgaa ttcatgaata aacttcatgt catttctggt
    20641 ttgattgatt tgaagaagta tgaagaagtc acccatttta tccagcagct aaatcaaaat
    20701 tataaaaaag agattggcca agtctcaagt ctgatcaaag tacctgcaat tgccggtttt
    20761 ttattaggca aaataaacga agccaaagaa caatctgttg aaatgctgtt agaaagcgat
    20821 tcttttatcc ctaaaatgga gatggatgac tccatccatt cacttttgca agtgttaggg
    20881 aacttacttg ataatgcaaa agaagccgtg ctacaaaaac atgaaagaaa cggacaggtc
    20941 cggattcatt taaactatga cacagaagct gaagtattca tcgtgaccgt ctgcgatgac
    21001 ggtgtcggga tatcagaaga aatctcagaa aaaatattta cgctaggttt ttcgacgaag
    21061 ggaatcaatc gtgggtttgg attgaatctc atccattcaa tcgtcaaacg ccacggtgga
    21121 tttttagaat tttccaaaca aacaaatggc ggtacaatcg tctatctaga attaccaaaa
    21181 aaggaagatc aaaatgatga caaatgtcct gataatcgaa gatgatccaa tggttgcaga
    21241 attgaatcgt acttttgtgg aaagcatccc taatatgaac gtaatcgaaa gtttcagaaa
    21301 tgtagaagaa ggaaaaaaat atttcagaca aaaaaacgca gatctgctgc tgcttgatgt
    21361 atacatgcct ggcgaaagtg gtatccattt tttatcttgg cttagacagc aaggaaatga
    21421 tatcccagtg attttgatca ctgctgcaga tgatatcgaa accataaaga atgtgatccg
    21481 ctacggtgcc ttagattatt tgatcaaacc gttcactttg caacgttttc agctggcgat
    21541 cgaaaagtat cttgctttct ctcagacaat ccaaacgact gaaaaagccg atcagaaatt
    21601 gatcgatcaa gtattcaacc acaccactcc cattcacgaa ataccatcat tcatcgattt
    21661 gcctaaaggt ctgtcaaaac tgactttaaa aaaaataagt gcatttattc taaaagaaga
    21721 tactattttt tcaacaaaag aactggctca aaaaagctca ctgtcacgta tatccgtcaa
    21781 gaaatatttg aattttttag tagaacaaga tatattgaac gaaagaatca aatatttgga
    21841 aatcggccgg ccgctaacct gttatgaatt gacaaagaat gggcggaaaa agctcacaga
    21901 ttactgttga gtcatcgaat tatcccatac aaaatagtcc aagtatacag aagtaacaac
    21961 tgtttacttg gactattttt aaacatttta ttgacgaata tccatgtttt cttatcttaa
    22021 ttgacgggct ttaggaagag atacctcatt tttcgttttt ccagtttcta ttatttcacg
    22081 aaagttctcg aaacttgtcg aaatcatatt tgataatgcc tcatctgtat ttgaacctac
    22141 atgcggggtt acaagaactc tagggtacat ttctactaat tgctggatag cagggtctgg
    22201 aatcgtctcc catggcttga aggatcggaa aaaaacctct gtttcatttg caaaaacatc
    22261 ggttgcaaaa ccagctaaat gattgctttt caaagctctt aaaatagctt cattatcttg
    22321 aagctctcca cgggctgtat taatcaagat gctacctttt ttcatttgag ctaaaaatcc
    22381 ttcattgatc atttgatcgt tttcacctgg gatatgaggt acatgaatac tgacaatatc
    22441 gcttttggct aataactctt caagcgagtg gaacgtcaat acttttttag cagcttctgt
    22501 ctgatgaata tcgtagccga tcactttggc tcctagtccc ttaaacaaaa cagcttccgt
    22561 caaccctatc ctgcctgttc ctatgatccc tactgtgcaa tttctgattt cacgactaaa
    22621 catttgctca tccactcgaa aatctttgaa agatgttcgg atcgtcgtat acgcagtatt
    22681 tctcaaaagc atcatggcaa aagtcaaaga taactctgct atcgcatttg gcgaatacga
    22741 tggtacacgg gctactgtca taccaaaatc agctgccgct tgtagatcga tatgattgac
    22801 tcccacagtc cgtgtaaaaa cataacgaat cccatattcc tgcatttttg caagattggt
    22861 ctcatctgct atacaatttc ccctcaacaa tacagcatca tggtcctttg ctgacacgat
    22921 attgtcatgt gtcaacagtt cttcataaag actgagatca taatggtaaa tattcaattt
    22981 ttcaaaaaaa tctatctcgt tcggacgaac accgtaacat gcgattctca tactttcttc
    23041 ctccatttct tatgaaaata aacctatgcc atgaatcatt tgtaatacaa cgatccatac
    23101 aggtgtcagt accacagcaa aaatagttga cagtaaggat gcattggagg ctaaaagtgc
    23161 ctccctatca aaactgatag cataggctgc tgccactgtt gcagctggtg tagccatcat
    23221 gataacgatt gttgccagtg cttcaaaatt gactggtaga atattcgttg ccgtcaaaac
    23281 tgctagaatc acgatattca atgcaggtac aaataccact ttgactagac tgtaatacca
    23341 tgaagttttt tcagatgcag cttttttgaa gcttacttca cctaatgttg cgccgattgc
    23401 tagccacgcc aatggtgaac ttaaaccagc taaataatcc atcggctgaa atagccacgg
    23461 tgcagtctgg tcaattcgca aaaacgctac ttggcttatc tctccttctg cacctgtaac
    23521 tgacacttgt ggcagatacc cttggaacag ccaaatgaaa aggccggcaa aagtagcgat
    23581 aatgattgga ttgacgaaca tcgctttgat atttttagct tccatcttca agccactcat
    23641 ttttatgtat ccataagaat acaaaaagat tcggtagcca atattgaaaa ttgaggaata
    23701 catcacgccg acaggaccat aaatcgcact gacgataggc gttccgaaaa aggtcgtaga
    23761 accaaagatc gtcaggacac gcaacgttgt ttgcttatcc cctttatagc ttaagaaaaa
    23821 aggttttgaa actagaataa gaataatata aataactaat ccccaaatca agacattgat
    23881 tccttgcatc agtaattctg tattgatatc ttgcatgaaa gctcgaaatg ccagtgctgg
    23941 caaagccact gttaagacga ctttcgatag aatttttcca acagattcag aaaaaatccc
    24001 cttttttcta caaacaaacc ctaataatat aataaaaact gttgaagtga ttgcactgac
    24061 aatcgacata tctgtcaaag tcgatcgaaa aatgtcaaat aagttcatct ttctcctcct
    24121 aattatgttc atttattcac aataaaaaaa gcttttattt tgctaatacg tattaacatt
    24181 tttaatttta tctttacatt gttacttatt gaacaatagg aaattaaaga aacttttgaa
    24241 acttatgtaa agtgatttt
//
LOCUS       DADVXE010000038        23828 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.039, whole genome shotgun sequence.
ACCESSION   DADVXE010000038 DADVXE010000000
VERSION     DADVXE010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.039"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(53..787)
                     /locus_tag="KB913_001665"
     CDS             complement(53..787)
                     /locus_tag="KB913_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBB6820029.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="KB913_001666"
     CDS             1114..1524
                     /locus_tag="KB913_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBB6820030.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="KB913_001667"
     CDS             1517..2218
                     /locus_tag="KB913_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBB6820031.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="KB913_001668"
     CDS             2218..3804
                     /locus_tag="KB913_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820032.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="KB913_001669"
     CDS             3823..4044
                     /locus_tag="KB913_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBB6820033.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="KB913_001670"
     CDS             4041..4802
                     /locus_tag="KB913_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBB6820034.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="KB913_001671"
     CDS             5182..5691
                     /locus_tag="KB913_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBB6820035.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="KB913_001672"
     CDS             complement(5766..6305)
                     /locus_tag="KB913_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBB6820036.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="KB913_001673"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="KB913_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBB6820037.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="KB913_001674"
     CDS             7318..8169
                     /locus_tag="KB913_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBB6820038.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="KB913_001675"
     CDS             8197..8832
                     /locus_tag="KB913_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBB6820039.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="KB913_001676"
     CDS             8852..9625
                     /locus_tag="KB913_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6820040.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="KB913_001677"
     CDS             10033..10830
                     /locus_tag="KB913_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBB6820041.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="KB913_001678"
     CDS             10808..11221
                     /locus_tag="KB913_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6820042.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="KB913_001679"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="KB913_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBB6820043.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="KB913_001680"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="KB913_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBB6820044.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="KB913_001681"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="KB913_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBB6820045.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="KB913_001682"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="KB913_001682"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBB6820046.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="KB913_001683"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="KB913_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBB6820047.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="KB913_001684"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="KB913_001684"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBB6820048.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGVFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="KB913_001685"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="KB913_001685"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBB6820049.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="KB913_001686"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="KB913_001686"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBB6820050.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="KB913_001687"
     CDS             21905..22483
                     /locus_tag="KB913_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6820051.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="KB913_001688"
     CDS             22535..23017
                     /locus_tag="KB913_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBB6820052.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="KB913_001689"
     CDS             23134..23508
                     /locus_tag="KB913_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820053.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7780 a         4286 c         5115 g         6647 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggtat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagttt
//
LOCUS       DADVXE010000039        23732 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.040, whole genome shotgun sequence.
ACCESSION   DADVXE010000039 DADVXE010000000
VERSION     DADVXE010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.040"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(105..680)
                     /locus_tag="KB913_001690"
     CDS             complement(105..680)
                     /locus_tag="KB913_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6820054.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(685..1659)
                     /locus_tag="KB913_001691"
     CDS             complement(685..1659)
                     /locus_tag="KB913_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HBB6820055.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1683..1727)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1942..2910
                     /locus_tag="KB913_001692"
     CDS             1942..2910
                     /locus_tag="KB913_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6820056.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            3007..3300
                     /locus_tag="KB913_001693"
     CDS             3007..3300
                     /locus_tag="KB913_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBB6820057.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3418..3654
                     /gene="secG"
                     /locus_tag="KB913_001694"
     CDS             3418..3654
                     /gene="secG"
                     /locus_tag="KB913_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBB6820058.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3757..4512
                     /locus_tag="KB913_001695"
     CDS             3757..4512
                     /locus_tag="KB913_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6820059.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4515..6872
                     /gene="rnr"
                     /locus_tag="KB913_001696"
     CDS             4515..6872
                     /gene="rnr"
                     /locus_tag="KB913_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBB6820060.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6894..7358
                     /gene="smpB"
                     /locus_tag="KB913_001697"
     CDS             6894..7358
                     /gene="smpB"
                     /locus_tag="KB913_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBB6820061.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7660..8379
                     /gene="atpB"
                     /locus_tag="KB913_001698"
     CDS             7660..8379
                     /gene="atpB"
                     /locus_tag="KB913_001698"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBB6820062.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8432..8647
                     /gene="atpE"
                     /locus_tag="KB913_001699"
     CDS             8432..8647
                     /gene="atpE"
                     /locus_tag="KB913_001699"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBB6820063.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8738..9262
                     /gene="atpF"
                     /locus_tag="KB913_001700"
     CDS             8738..9262
                     /gene="atpF"
                     /locus_tag="KB913_001700"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBB6820064.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9249..9791
                     /locus_tag="KB913_001701"
     CDS             9249..9791
                     /locus_tag="KB913_001701"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBB6820065.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9814..11370
                     /locus_tag="KB913_001702"
     CDS             9814..11370
                     /locus_tag="KB913_001702"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBB6820066.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11384..12286
                     /locus_tag="KB913_001703"
     CDS             11384..12286
                     /locus_tag="KB913_001703"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBB6820067.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12309..13715
                     /gene="atpD"
                     /locus_tag="KB913_001704"
     CDS             12309..13715
                     /gene="atpD"
                     /locus_tag="KB913_001704"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBB6820068.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13729..14151
                     /locus_tag="KB913_001705"
     CDS             13729..14151
                     /locus_tag="KB913_001705"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBB6820069.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14620..14850
                     /locus_tag="KB913_001706"
     CDS             14620..14850
                     /locus_tag="KB913_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBB6820070.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14947..16248
                     /gene="murA"
                     /locus_tag="KB913_001707"
     CDS             14947..16248
                     /gene="murA"
                     /locus_tag="KB913_001707"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBB6820071.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16261..16437
                     /locus_tag="KB913_001708"
     CDS             16261..16437
                     /locus_tag="KB913_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBB6820072.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16572..16868
                     /gene="yidD"
                     /locus_tag="KB913_001709"
     CDS             16572..16868
                     /gene="yidD"
                     /locus_tag="KB913_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBB6820073.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16932..17399
                     /locus_tag="KB913_001710"
     CDS             16932..17399
                     /locus_tag="KB913_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6820074.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17484..18368
                     /locus_tag="KB913_001711"
     CDS             17484..18368
                     /locus_tag="KB913_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6820075.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18482..18718
                     /locus_tag="KB913_001712"
     CDS             18482..18718
                     /locus_tag="KB913_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBB6820076.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18806..18886
                     /locus_tag="KB913_001713"
     tRNA            18806..18886
                     /locus_tag="KB913_001713"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18840..18842,aa:Tyr,seq:gta)
     gene            18893..18964
                     /locus_tag="KB913_001714"
     tRNA            18893..18964
                     /locus_tag="KB913_001714"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18925..18927,aa:Gln,seq:ttg)
     gene            19090..19260
                     /locus_tag="KB913_001715"
     CDS             19090..19260
                     /locus_tag="KB913_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820077.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            19480..20187
                     /locus_tag="KB913_001716"
     CDS             19480..20187
                     /locus_tag="KB913_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6820078.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(20246..20890)
                     /locus_tag="KB913_001717"
     CDS             complement(20246..20890)
                     /locus_tag="KB913_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBB6820079.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            21017..21304
                     /locus_tag="KB913_001718"
     CDS             21017..21304
                     /locus_tag="KB913_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820080.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            21412..21732
                     /locus_tag="KB913_001719"
     CDS             21412..21732
                     /locus_tag="KB913_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6820081.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            22050..23126
                     /locus_tag="KB913_001720"
     CDS             22050..23126
                     /locus_tag="KB913_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBB6820082.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            23123..23732
                     /locus_tag="KB913_001721"
                     /pseudo
     CDS             23123..23732
                     /locus_tag="KB913_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
BASE COUNT         7842 a         4142 c         5106 g         6642 t
ORIGIN      
        1 aatctgagcc agaatgtggt tcattctgac tcagatttga ttttgcacaa ctcatcagtc
       61 cttattgaca aagagcctta ttttgctaat ccagctctgt ttattcagcc tatttttctt
      121 tttgaatata tcaagcgttg tggcaacata gtgatgacta atgaaacaac gacgatagac
      181 aacaaacgat caaggtagtc tgtacctgcc tgtaccaaga tcacacttgt tgtctgactt
      241 aaacctaacc catgtaatag ctgaacgatc atactggatc ctgaggaggt gatcccgcca
      301 aataactgaa cggtaatgat cgaagaaacg atcgttccag gtaccgacaa aatcaaagcg
      361 agtaataaca gtttcaagct gtttttatct ttgccgagat atcttggcaa aatcaatcca
      421 gcaagcaagc ctgtgagaat ttggattggc gaataataca gagaaaaaat atctgtagtc
      481 actccactta aaataccgct ggacaatcct gtcagcattc caggtacagg cccaagcaat
      541 gcaccagcaa aaatcgttcc gatagaatcg agatagattg gcaaacgaag ccataaagca
      601 atcgttcctc caatataatt gatcccaata cacaaagcca tcactgtaag tacgcgagtt
      661 gccattttgt ttttattcat tttgttagcc catctttaac ctttccaaat ctttcataat
      721 cgtttcttct tgtgcattta aaagaacggt taaaaacttt cggaaaaaaa gacgagtatc
      781 tacttttgtc ataattttac tgttagcagg tttctgccaa aattcataac gatcaaccaa
      841 tgtttgtcca cgacttattc cttgagtttc cacagcagtg aagcttttga aaccttcaca
      901 gatggcctcc tcgataaaat aagcaacagc taacggatca ttgatgacac atcctaaaat
      961 tctttcttgt ttccagtgga agtcaaaata aaaacgagtg atcgctttta gatactctcc
     1021 ctcttcagga ttcatttgac agcagtattc gaggatagtc ggtgtcaaga cgatttctct
     1081 tgtcacatct aacccaacca tttctatcgt ttgtttgaga ttctcgaata cataagaagc
     1141 tgcttcagga tcacaccagt aattgtattc agcaactggc gaacagttac catggctttt
     1201 gtaagttcca cccatcgaga caaaacgttc catatgtttc ccaatatttg ggttgacttt
     1261 caaagcagaa gcgatattgg tcaaaggacc caaagcaatg actgatgtat ttgtcttttc
     1321 tttgaaataa tcagccaaaa aatcaacggc atggagaggt tctgcctgtt ttctcaagat
     1381 catcgggaaa tttgtttccc ctaaaccatc cataccatga gtgtcttgtg cactgatgaa
     1441 aggttgcttc aaaggttttt ccattccttg ataaacagga atgtctaaac gatcacagcg
     1501 ttccaggcat ttcagcacat tctgcgtacc tatatctgca gggacattcc cacaaactac
     1561 ggtaatagca actacttcga tatcagggga tttgacagct aatgataaag ctaaagtgtc
     1621 gtcgatccct ggatcgcaat caataattac ttttcgcatt atttccaatc tcctttcttt
     1681 agagatactt agttttttat tctgggaagt ttccgaacca gtccaagacg agcgtcttga
     1741 ttataatgca cgaaattagt atactggctt ttattgcgaa tgtaaatgct ctcttacaag
     1801 taaatctatt gaggagaact ttaagtaaat gatacaatga aaaagaaatg gaatttacgt
     1861 gtgccgaaaa taaagaatcc tatggatcgg tacattggat aatagataga ttatagtttg
     1921 gcagaaagcg gcgggtgtac aatggttatt ttttatttca ttcttattct gataattata
     1981 gggatcagtt accattttct ttcttatttt tatgcaaaga aattagtaag agcgggagta
     2041 cagagaggat atgactggta tgaagacact ggtcatcgtt tgatggaccc tgctgcagtc
     2101 acgtcagtag aaaaaaaacg acaaaaatta gaagaagagt gtgaaagctt ttgggagcag
     2161 ggaacaccca aaacaatcaa aagttatgac gggttgaaac tagctggtca gatgttcatc
     2221 catccaaata agcagaataa atgggtcatt tgcgtacatg attaccgaag cacagggaaa
     2281 agagacatgt ctcatatagg taaaagatat gcagagaaag gattcaacgt tcttgtacct
     2341 gatttacgtg cgcacggaga aagtgaagga gaaatcatcg gaatgggatg gctagatcgg
     2401 ctagatttaa ttgcctggat ccaactcatc ttagatgaac agccgaatgc gtccattatt
     2461 ttacacggcg gatcaatggg agcttctacg atcatgatgg caagtggtga aaaacttcca
     2521 tcagcggtca aaggatttat tttagacagc ggatatgttt ctgtttatgc agaattccga
     2581 tatatgttaa gtaaaatcac tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat
     2641 tatgcccaga aatacgccgg ttactcctta aagcaagcat cagctacgag acagcttggc
     2701 agcaatcatc tgcctttatt agtcatccat ggtgaaagag atcattttgt ccctacagaa
     2761 gcagcgtaca cgattcaaaa tgctacggca ggggataaag cactgctgct tgttccggaa
     2821 gcagaacact tggaagcatc gatgaaagat ccgaaaacct attggacagt gattttttca
     2881 tttattgaac aaagaataac gatgaattaa ttttctcttc ttttttgtaa gtaattcgag
     2941 gataaataat tgtttataga tcaggagact gctaaaataa ggtaggaata aaaaaatatc
     3001 agttatttga ggagtgcggc atatggaaat caaagaagaa aaaatcgtct tgctttattc
     3061 aatgatgaac aacaagagat cggagaaatg acatggtcag atgcgggccc agacatcatg
     3121 atcgttgacc atacatttgt agatccagca tatcgtggtc aaaagttagc tgaaaagcta
     3181 gtgtatactg gagtagaatt agcaagacga gacgggaaaa agatcattcc tttatgccct
     3241 tatgcaaaaa aagagtttga aaagaaacca gaatatcaag acgtcttacg tcagtcataa
     3301 gaataacagc tgaaagtttt gaactttcag ctgttattcc atttatatag agttgtcacg
     3361 gacttttatc tatgataaag ttaaagagac gatatctttt gggaaggagg ctgcgatatg
     3421 tataatttaa ttttgggaat cgtgatcgtt ttatcgattg ttatggtcat tgcgattatg
     3481 atgcagccaa gcaagcaaaa tagtgcagcg agtgcattta ccggcggtgc ggatcaacta
     3541 ttcggcaaac aaaaagctcg cggctttgaa gctgtcatgc agcgatcaac tgcagttatg
     3601 ggagctatct ggatgatctt attatttgtc ctagcatatt tatcttcgaa gtagttgaat
     3661 aagcctctcg caaaacggcg ggcggctttt tttattgcaa agagaacgct taagaagaag
     3721 ttatgaaaga aactatggta aaatgaggcg aaagaggtga gacgagtgag acaattacca
     3781 aaaccccttt atgcaaaaca tggaaagcga gcggttttgc tgcttcacgc ttactcagga
     3841 agtccaaacg atgttcgaat gctcgcacga tttttggaaa aagcagatta tacagtttat
     3901 gcgccgcttt ttaaaggaca cggaacaatg gagccatatg atatcttgca agaaaaagca
     3961 gaaagctggt gggcagacac taaaaaagcc atccattttt tacagtctga gcagttttct
     4021 gatattgccg tattaggatt atcaatgggc ggcatctttg ctgtacgagc actagaagaa
     4081 gaatcagtga ttggcggcgg ttttttctgt tcgcctttgt ctcctgtaaa aacaaacgtg
     4141 cctgaaaact ttgaaaaata cgtacgtcaa gtgctgaaga cagcaggtaa atcagagaaa
     4201 gaaatcaatg aaaaagcagt tgcttaccgc tcgttagctg aacaacaatt aatggatata
     4261 caagatcagg cagcaatcgt agaaagtagg ttgtcagata tccaacagcc gatattttta
     4321 gctcaagctg ggaaagatga aatgatcgac cctaatggcg tatttgaaac tgcacgcaag
     4381 ttgagccgtc agcgagtgac acttcaatgg tatcctgaaa gtggtcatgt gattacagtt
     4441 ggtacagcaa gacgcgaatt agaaaaagac gtcttggaat ttttagaaaa attaccttgg
     4501 aatgaggaat aaatatgaca aaagaaacga taaaagagaa aattctcttt ttcatggaaa
     4561 gcagtcgcaa acgcagtttt tctatggaag aaatcgctga aggtttaggg ttccaaaaaa
     4621 gcgatgattt taaattacta gtacaaacga ttgctcaaat ggaaagagaa cagagtatag
     4681 ttttcaataa aaaaggaaaa gtgaaacttc ctttaaaacc aatcctgatc gaaggaacat
     4741 ttcgagcaaa tgaacgagga tttggatttg taacgattga tcccgaagaa gatgacatct
     4801 atatcccaaa agaagcgact ggttttgcaa tggatggaga caccgtagca atcgatatca
     4861 tgaagcgagc aaatacagat atggatcgcg gagcagaggg gaaagtagtc gagattcgag
     4921 accgggcgac tactcagtta gcaggggaat tcgttgctta ttcagaagaa gaaatacaag
     4981 aaacagatct ttacggcgtt gttatcccga aagatagaaa gctcaaccaa tttaaagtat
     5041 atgcagcagc agagggagtt cgtccagttg acggaagtat tgtgctgatc gaactgaccc
     5101 attaccctga aaaagggtat gcgactagtt tagaagggat aatcaagcaa gtgattggtc
     5161 ataagaatga ccctggcatg gatatcctct caattgtcgt ggctaatggt atccctacga
     5221 aatttcctga tgatgtattg tctgaagcag atgaagttcc agatcaaatc agcgaaaagg
     5281 atataactgg acgtagagat ttaagaaatc agctcattgt tacgattgat ggagaagatg
     5341 caaaagatct agatgatgca gttacggtta aaaaattaga taacggtaat tattttcttg
     5401 gagtacacat tgcagatgtt tcttactatg tgacacaagg cagtcaattg gacagagaag
     5461 catatgaaag agggacaagt gtatatttga ctgatcgagt aattccgatg atcccgcaac
     5521 gtttatcgaa tggtatctgt tcactgaatc cccatgttcc aaggctgacc atgagttgcg
     5581 aaatggagat tgatccaaat ggacaagtag tctctcatga tattttccca agtgtgatcc
     5641 aaacaacaga acggatgacc tacacagctg tcaatcaaat cttagaagat caagacgaag
     5701 aaacgatgca acgctatgct cagctcgtac ctatgttcca agaaatgggt gaattgcacc
     5761 gaatccttga aacgatgcga atcaaacgtg gcgcgatttc ttttgaggat cgcgaagcga
     5821 aaatccttgt tgatgctgaa ggacacccaa atgacatcca gctaagaagc agaggaattg
     5881 gtgaacgctt gatcgaatct ttcatgcttg cggccaatga aacggtagct gaacattata
     5941 ataaattaaa tctgccgttt atttaccgaa tccatgaaca gccaaaagaa gaaaaaatgc
     6001 agcgcttctt tgattttgct tcagctttgg gcattctggt ccgaggaacg aaaggaacga
     6061 tcacaccaaa agatttacag catgtgatcg aaggagtaga agacaaacca gaagctgcag
     6121 ttatcaatac tatgttgcta agaagcatgc aacaagcacg ctattcagaa gacaattttg
     6181 ggcattatgg cttagcggca gattactaca cacactttac atctcctatt cgacgctatc
     6241 ccgatctaat cgtccatcgt ctgatccgtt cttacagtga agataaaagt gaaagcaatc
     6301 aaagttcgtg ggctgcggaa cttcctgaaa ttgcagatca tagttctaag atggaacgtc
     6361 gtgcagtaga aacagaacgt gaagtagatt ccatgaagaa agcagaattc atgatggaca
     6421 aagtgggaga agaattcgat gggatcatca gctctgttgt gaaattcggc ctgtttatcg
     6481 aactgccgaa tacagtagag ggattgatcc atatcaatga attgaaacag gactacttcc
     6541 attttgttga aaatcattta gctcttgtag gtgaaagaac tggtctgact tttaaaatcg
     6601 gacagaaagt gcgagtaaaa gtagtcaaag ctgatccaga tgaacgagca gtagattttg
     6661 aacttgtttc cgcagaagag gttacagcgt tggaacggcc aaaaacacga aatggaaaat
     6721 caggaaaacg cgaaggaaaa caagcaggaa aacgcccaga aagaaatggc aagaagaaca
     6781 aacgatatag cgatagtaag caaacgttcg gtaagaaaaa agggaagaag ccattttaca
     6841 aaggtgttaa aaagaagaaa aagaaaaaat aaaatgagtt ggaggaaaca gctatgccaa
     6901 aaggcgaggg aaaattaatt gcacaaaaca agaaagctcg ccatgattat tcgatcatcg
     6961 acacgatgga agcagggatg gtcttgcaag gaaccgagat caagtcgata cgaaacagcc
     7021 ggatcaatct aaaagatgga tttattcgcg tccgcaacgg agaagctttc ttgcataatg
     7081 ttcatatcag tccttatgaa caaggaaata tttttaatca tgatccgttg cgcacgagaa
     7141 agttattatt acacaaaaaa caaatcatcc ggcttgaaaa tgaattgaaa aatactggaa
     7201 tcactgttgt tcctttaaaa gtctatattc gtaacggcta tgccaaggta ttgattggtc
     7261 tggcgaaagg gaaaaaatct tatgataaac gggaagattt gaaacgaaaa gatatcgatc
     7321 gacaaattga tcgaacatta aaaaatttct ctagataatt tcattatcct ttttcgcata
     7381 ttcggtgctt ttgcttttac ttaatgataa aatttgttag catttaatct gataaaacat
     7441 gattatcata ggttttttct tagatcagga gcaccgtgta taaagaaaaa ttcgcttcgt
     7501 ttttgactga aataaaaaag tgtctaattt tcatgaaaat gttttgaatt ttctgtttca
     7561 tggtggtatg ataccgtgtg gttagaaacc gattggaaaa aaccagatac gcacatgaat
     7621 tgattttatg tgaatttcgg ggaaaagagg tgaaatggat tggatgaacg ctcgctaacg
     7681 ttccacattg gaccaatttg gtttgatggt acagtttgta taatggtgtt actgacctgt
     7741 ttgattgttt tcttcttagc ttactttttt acaagaaatc ttaagttgaa accaacaggc
     7801 aaacaaaatg cgatagaatg ggtcattgat tttagtcgag gaatcgtaac agataatctg
     7861 cctagaaaag aattgagcaa tttccatttg ttggcattta cattgttttt atttgttttt
     7921 gttgcaaaca acatcggttt agtaacaaaa atcgttttac ctaacgaaac aacactttgg
     7981 aaaagcccga cagcagaccc gtttgttact ttaactttgg catttataat gatcttactt
     8041 actcacttat tcggggtgaa aaagttaggc ttcaaaggat atttcgtaaa ttcgttcttg
     8101 aaaccctata gttttatgtt tccgatgaaa ctgattgaag aatttacaaa cttattaaca
     8161 cttgctttac gtctttatgg gaatatttat gcgggggaag ttttgctaac cttgattgca
     8221 aaaatgatga caagcttagg ctggttctca ttaccattag caattccatt agagatggtc
     8281 tggatcgcgt tctccttgtt tattgggagc atccaagcat ttgtctttgt cactttgtca
     8341 atggtttata tgagccataa gattgaagta gaagaataat actcggttaa aaaacaaact
     8401 actatttatc tattttagga ggaaaacaat tatgaattat atcgcagcag caatcgcaat
     8461 catgggagca gcaatcggag ccggttatgg taacggtcaa gttatctcta aaacaatcga
     8521 atcaatggct cgccaacctg aaatgtctgg tcaattccgt acaacaatgt ttatcggggt
     8581 agctctagtt gaagctgttc ctatcttagg ggtagttatc gccttgattc tagtttttgc
     8641 cgtttaattg aatcagtatt aaggcagaaa caacatcgtt tgttactgct tttttacatg
     8701 gaaactagaa atactccaaa gaaaggaagg ctcgcctatg ctgaatcaat tggcaattgc
     8761 agaagttggc aatgcgatgt taggtaatat catcgttgtc agcggctcat ttttgatact
     8821 actggctctc ttgaagcact ttgcttgggg accaatcagc gatattttga aaaaacgtga
     8881 agacaagatc gccaatgatt tagattctgc agaacaatct cgcatcaact cagcgaaaat
     8941 ggaacaagaa cgcgaacaac aattgttagc ctctcgttct gatgcagctg atatcatcaa
     9001 aaatgcgaaa gaaagtggag aattaagccg ccaaaatatt ttgaaggatg ctcaagaaga
     9061 agcagctcgt ctaaaaagca aagcccaagc tgatatcact gtagaacgtg attcagcgct
     9121 gaactctgta aaagacgacg ttgcagaact ctctcttcaa atcgcggaaa aaatcttgaa
     9181 caaagaatta tctccagaaa tgcatgaatc attaatcaat caatacattg aaggtctagg
     9241 ttcttcaaat gaaactagat aaatatacag taggaagacg ttacgggaaa gctttatttg
     9301 aactggcgat cgattcaaat caagcagaag aaatctatca agatctcgta agtttacgtc
     9361 aaatctatga acaagtacct ggattaggga atatgttaag tgatgttcgt ctagaacctc
     9421 atgaaaaacg agaaatcatg gacaagcttg tcagcggtta tgatgggatc gttaaaaact
     9481 ttttagaagt tgtttatgag tataaccgaa tggatgacct tttgttcatg atcgaagaat
     9541 atgaacgtcg atatgatgaa catcaagggt tactattggg aagtgtcaca acagcagtcc
     9601 cactttcaga cgaacaacga atacaattag aaaagaatgt tgcaaaaaca atggactatc
     9661 aatcagttga attaaaacaa atcgttgatt cttctattat tggtggcgcg attgttgaag
     9721 ccaaccatcg agtaatcgac ggaagcattc gcacgcaatt agaaaaaatg cgtaatcaat
     9781 taaacagata gtacaaagag gtaggtgaat cgaatggcca tcaaagcaga agaaattagt
     9841 gccttgatta aagaacaaat tgaaaattat caaaacgtgc tttcagtcga agaaatcggt
     9901 accgtaactt atgtaggtga cgggatcgct cgtgcacatg gtttagaaaa cgcgatgagt
     9961 ggtgagttgc ttgaattttc aaacggctca tacggaatgg cgcaaaactt agagtcaaat
    10021 gatgtaggta tcattatcct tggcgatttc gagtccattc gtgaaggaga taaagtaaaa
    10081 cgaacaggta agatcatgga agttccagtt ggagaggcct tgatcggtcg ggtagtcaat
    10141 ccgctaggtc aaccaatcga cggactaggt gaaatcgtta ctgacaaagc tcgtccagta
    10201 gaagcgatgg caccaggtgt tatgcaacgt aaatctgtta acgaaccaat gcaaacaggg
    10261 ctaaaagcga tcgacgccct tgtgccaatc ggacgcggac aacgtgaatt agtcatcggt
    10321 gaccgtaaaa cagggaaaac ttctattgcg atcgatacga tcatcaacca aaaaggtcaa
    10381 gatatgatct gtatctatgt agcaatcgga caaaaagatt ctacagttcg tacacaagtt
    10441 gaaacattga aaaaatatgg cgcaatggat tacacaatcg ttgtgaatgc cggtgcgtct
    10501 caaccagcac cattgcttta tatcgcacca tatgctggta ctgcaatggg tgaagaattc
    10561 atgtacaacg gtaaacatgt attgatcatt tttgatgatc tttcaaaaca agctgttgct
    10621 tatcgtgaac tttccttgct acttcgccgt ccaccaggtc gtgaagctta tcctggggat
    10681 gttttctact tgcactcacg tttattagaa cgtgcagcaa aattaagtga tgatttaggt
    10741 ggcggttcaa tgactgcctt accatttgtt gaaacacaag ctggagatat ctctgcttat
    10801 atcccaacaa acgttatttc gatcactgat ggacaaatct tcttagaaag cgacttgttc
    10861 tacgcaggta ctcgtccagc ggttgatgcc ggactatctg tatctcgtgt aggaggttct
    10921 gcgcaaatca aagcaatgaa aaaagttgct gggactttac gcctagactt agcaagttac
    10981 cgtgaattag aagcatttac acaattcggt tctgacttgg atgcagcaac acaagcaaaa
    11041 ctaaatcgtg gacgccgtac agtagaaatc ttgaaacaaa aattgcatgc accgctagct
    11101 gttgaaaaac aagtagtgat tttgtatgct ttgacacatg gattcttaga tagtatccct
    11161 gtagacagta ttttagactt cgaacatgaa ttattcgaat atctggatac caatcattca
    11221 gatatctttg aaacaatccg tacaacaaaa gatcttccag aagaagaagc gttgaacagt
    11281 gcgattcagg aatataaaga catgttctta gctacaaaag gaagtaattc ctctacagaa
    11341 gataaattga aatccattca aaatgcatag tgaggtgaga tgaatgggtg cttcattaaa
    11401 tgaaatcaag acacgtatcg cttcaacgaa aaaaacgagc caaatcacgc gggcaatgca
    11461 gatggtgtct gcttctaagt tgacaaaatc tgaagcttct tcacagaagt ttcaggttta
    11521 tgcaacaaaa gtaagagaaa tcgttacgca tttgactgct actcagttaa atgatattgc
    11581 ctcagaaaat cctagagggg atatcaatta caacagcatg ctgctcagcc gtcctgtgaa
    11641 gaaaactggt tatatcgtca tcactgcaga tggcggttta gtcggtggat ataacagctc
    11701 gatattgaaa caaacgatgt ctattttaga agaagaccac caatcacccg atgattacgt
    11761 gatgatcgca attggcggaa ctggtgcaga cttctttaaa gcacgcggta tcaatctagc
    11821 atatgagctg cgcaatctat ctgatcagcc aagctttgat gaagtccgca aaattgtaaa
    11881 tatggcaaca actatgttcc aaaacgaagt attcgatgaa ttatacgtat gttataacca
    11941 tcatatcaat tcgctaacta gtcagtttcg tgtagaaaaa atgctgccaa tctcagactt
    12001 agatccagaa gaagcaacga ctttcgaaca agaatatatt tttgaacctt caaaagaaga
    12061 aatcttgtct cagttattgc ctcagtatgc tgaaagtttg atctacggtg cgatcgttga
    12121 cgccaaaaca gcagaacatg ctgctggtat gacagcaatg aaaacagcaa ctgataatgc
    12181 tgctaatatc attgatgagc tgacggtttc ttataaccgt gcaagacaag gggctattac
    12241 ccaagaaatt accgaaattg ttgccggagc ttcggcacta gaatagtatt gagattggag
    12301 gaaaaaagat gagttcaggc aagattgttc aagtaatcgg tcccgttgtc gacgtggaat
    12361 tttctttaga ccaatcctta ccagatatca acaacgcatt agttgtttat aaaaatgacg
    12421 aaaataaatc aaaagttgtt cttgaagcag cgttagaatt aggggacgga gtgatccgga
    12481 ccattgcgat ggaatcaaca gatggtttac aaagaggaat ggaagtcatt gatacaggca
    12541 aagcaatctc tgttcctgta ggtaaagaaa cattaggtcg cgtattcaac gtactaggag
    12601 atacgatcga tttagaaaca cctttcccag aagatgcgga aagaagcgaa attcataaaa
    12661 aagcaccagc ctttgacgaa ttaagtacaa gtacagaaat tttggaaaca gggatcaaag
    12721 ttatcgattt gcttgcccca tatttaaaag gtgggaaagt cggactattc ggtggtgccg
    12781 gtgttggtaa aaccgtactg atccaagaac tgatccataa tatcgcccaa gaacatggtg
    12841 gtatttctgt atttaccggt gtaggtgaac gtactcgtga aggtaatgac ttgtattatg
    12901 aaatgaaaga ttcaggagtt atcgaaaaaa cagccatggt gttcggacaa atgaacgaac
    12961 caccaggtgc acgtatgcgt gttgctttga ctggtttgac gattgcggaa tatttccgtg
    13021 atgtagaagg tcaagatgta ctgttgttta tcgacaacat tttccgtttc actcaagctg
    13081 gatctgaagt atcagccttg ttaggacgga tgccttctgc ggttggttat caaccaacat
    13141 tggcaacaga aatgggtcaa ttgcaagaac gtatcacatc tacgaaaaaa ggttcgatca
    13201 catcgatcca agcaatctat gtgccagccg atgactacac tgacccggcg ccggcaacag
    13261 cattcgccca tttggatgcg acaaccaact tggaacgtaa attaacagaa caagggattt
    13321 atccagcggt agatccattg gcttcttctt caagtgcttt agcacctgaa atcgtgggag
    13381 aagaacatta taaagtagca acagaagtcc aacacgtatt gcaacgatat cgtgaattac
    13441 aagatatcat tgctatctta ggtatggatg aattatccga tcaagaaaaa gtgttagttt
    13501 ctcgtgcccg cagagtccaa ttcttcttgt cacaaaactt taacgtggct gaacaattta
    13561 ctggtcttcc aggttcatat gtccctgtag aagaaacagt gaaaggattc cgcgaaatct
    13621 tggaaggcaa atacgatgat cttcctgaag aagctttccg aagtgttggc cgaatcgaag
    13681 acgtcgtaga aaaagcgaaa acactaggct actagaaagg ggtgccccat ggatcaatat
    13741 ttaacagtaa atgtggtaac tcctgccggt ttggtctatg atcaccatgc agctatcgtc
    13801 gttgcacgta cgacagctgg tgagcttggg attttgccta aacatgcacc aatcatcgtt
    13861 ccattgacga ttgatgaagt tcgtgtaaaa cgaacagatt cagataccca cgtcgattgg
    13921 atcgctgtta atggcggaat catggaagtt cgtgataatg ttgtttcaat cgttgctgat
    13981 agtgcggaac gtgaacgtga tatcgatgta tctcgtgcgg aacgtgcaaa acaacgcgca
    14041 gaacgccaaa tcgaagaagc aaaagcaaaa caagatacga acgaattgaa acgggcaact
    14101 gttgcgttgc accgagcaat caatcgtatc aaagtatcta agcactcata aaatgagatg
    14161 cggatgttta tccgtgttta agaacagtaa aaagaggtta tgacagaagt ggtcagcttc
    14221 aagacataag aaggaattta cgaaaattgc ttctcaaatt tttgtgaaat ctcagcttat
    14281 ttttcgaaga agctacttct ggaacaccgt atatcagagg ttgtgaaatc agcgttttgt
    14341 cctgagtatt agagaaacaa atggaaaata gttcctcata ttttgccgtt ttttgagcta
    14401 ataccgaggg tcagatgatt gaacaccgtt tatttggaat aagggactgc gacaagactt
    14461 ttgtctcagt cccttttttt gcatattttt agcatttatt tcctaaaaaa tgtaagggga
    14521 ttcctatatt tttaagtata cttgtttttc cttttataca ttttatggta ttatcatttt
    14581 attagttatt ataaaacaat cgttagaaag gacgtcatta tgcaagtata cggaattgat
    14641 gcggtgcttc gaatcgtgag tcatttggcg tttatctact tagccttctg gtctttacgt
    14701 tcgttacgca ttgaaacttt tttcagacca atgcataata cgcaaattag aatggcaatc
    14761 gtactttttt caattttttt agggtacact gcaagtaatt ttttcttaga ggttatcgct
    14821 ttatgccgaa atcttttcgt tagcctgtaa attttaaaaa aaggtactat tttaaaagca
    14881 aggatgttat aatagaaaag attttgagta agtgtatgct cattggaatt ttttggaggg
    14941 aacaacatgg aagagatcat cgtaagaggt ggcaatcaat taaatggaac agtaagaatt
    15001 gaaggagcta aaaatgctgt tttgcctatt ttagctgcta gtttgttagc agaagaaggt
    15061 attacgacat tagacaacgt tccgattctt tctgatgtct tcactatgaa tcaagtgatt
    15121 cgtcacttaa acgtagatgt agattttgat gaacaaaaga atcaagtaac aatcgacgct
    15181 tcaagacaat tagaaatcga agcgccttat gagtatgtta gtcaaatgcg tgcttcaatc
    15241 gttgtgatgg gtccgctact tgccagaaat ggacatgcaa aagtagctat gcctggtgga
    15301 tgtgcgattg gtaaacgacc aatcgatttg catttaaaag gatttcaagc tttaggagca
    15361 aaaattattc aaaaaaacgg ctatatcgaa gcaattgcgg atgaattgat cggtaacacg
    15421 atttatttag atttccctag tgtaggtgct actcaaaata tcatgatggc tgccgtaaaa
    15481 gcaaaaggaa caaccatcat tgaaaacgta gctcgcgaac cagaaatcgt tgatttagca
    15541 aacattttga ataaaatggg cgctcaagtc tatggagctg gtactgaaac aatgcgtatt
    15601 gaaggcgtgg atcatttaca tgcagtcaac cactcaatcg tacaagatcg tatcgaagca
    15661 ggtaccttta tggttgctgc tgcaatgaca caaggcaatg tgctgattgc agatgctatc
    15721 tctgaacata accgcccatt gatttctaaa ttgatcgaaa tgggtgcaga aatcattgaa
    15781 gaagaaggcg gagtccgtgt catcggacca aaacatatct tacctacaga tgtaaaaacg
    15841 atgcctcatc ctggtttccc tacagatatg caagctcaaa tgacagctat ccaattagtt
    15901 gcagaaggta caagtgtggt gactgaaaca gtgtttgaaa atcgtttcca acatttagaa
    15961 gagatgcgcc gtatgaacgc tcatgtcaaa atcgacggaa atgtagcaat catggatgga
    16021 aaccatgaat tgcaaggtgc agaagtatat gcaacagact tgcgggcagc agcagcatta
    16081 gttttagctg gcttgaaagc aaatggaatc acacgtgtgc gtaacttgaa ttatctagac
    16141 cgtggatatt ataatttcca tatcaaacta cagcaattag gtgcagacgt cgaacgtgta
    16201 gacatggatc aaacttctgc tgaaaaaaca gcacaaacga ttgcttaagg aagtggctga
    16261 atgagtaacc aacgatatat cttattaact ttgataaaga ttttagtggt gatcttattg
    16321 cttatccttc tttttgtggc cggaacgatg atcggatatg gtgtcatcgg tggcggcaat
    16381 ccatttaaag tattccagcc aagtttgtgg attcatattc gagacttttt tcattgataa
    16441 ataagaatca cagtggttct agtcgatatg aagtgagcca tgaagcagaa catgataaaa
    16501 gaaaacagaa gggaacgttg acgttagtcg cgatcccttt ttttagtaaa agaaaagaag
    16561 gaatctaatt gatgaagaag atattgattt atttagttag aggatatcag cgctttattt
    16621 cgcctgcatt tccacctagc tgccgttatt acccaacctg ttccaattat atgataaaag
    16681 caattcaaac ccatggtgcg ctaaaaggga cggtaatggg gactgcacgg atcttacgct
    16741 gtcatccttt tgtcaaaggc ggtatcgatt atgtaccatt gacattccga ttaacgcgaa
    16801 ataagaaaga taaaaaagaa ccagattata aaaaggttgt gaaaaatacg ggtagcactg
    16861 agcgataaag aaaaagagga aatttattgt caaagtaaca actccgcaac tacttatatg
    16921 ggggacaaaa aatgatcgaa gaactaaaca agaaagattt accatggtcc ttgttattag
    16981 atgcagatcc tgataaagaa aaagttcaag tatatgtttc cagagggagt ggctggatat
    17041 ggaaagaaaa agaaaaaaca ataggtgtac tgatctatgt ggcaagggaa aaagaatacg
    17101 aaatcgtcaa tgtagcagta accccaacgt atcaaggaaa ggggattggc ggaaaattac
    17161 ttgagacagc ttttcagaag ctttcacagc tagcttcaaa ccaaactcgg atcattatac
    17221 gtactggcac tactagtagc gctgcgttac acctctatca aaaaatgggc tatgtggaga
    17281 ttggtcgagt caaagactat tttatccatc attactctga gcccattttt gaaaatggag
    17341 atcaattaag ggatcaagtg attttagcaa ttcacttacc taaaaatagc tttaactaat
    17401 aaactttcaa ttcgagaaaa tgctttcaaa tgctaaatag atacattaca atagctttag
    17461 caaacaaaaa ggagaatatt tttatgggaa tattagtttt tgattttggt ggatcggctg
    17521 tcaaatatgg ttgttgggat ggcaaagaga ttaaaggtaa gggacaattt gcaacgcctg
    17581 aatcttggga agaaatgaaa acgcaattat ttcaagttta taaaaaaata ctcgtttctt
    17641 ttgaagtcga aggaattgga atcagctctc ctggagtagt gaataatgag aaacaggtga
    17701 ttgagggaat cagtgcgatt ccttatattc atggatttaa tattttccga gatttggaaa
    17761 ctctgtttca actcccagta acgattgaaa atgacgccaa ctgtgccgga atggctgaat
    17821 tttatgaagg tgctgcccgt gattatcaag atgttgcttt tgttgtggca ggaactggga
    17881 ttggcggggc gttgttcacg aaaggacaaa taaataaagg ggcacatctt tacggtggag
    17941 aatttgggtt gatgttctta gatggcgata agacattcag taaacttggt acagcggtac
    18001 agatggcttg gcgttattgt gaacgcaaag gtctcgataa aaatgcttat accggaaaag
    18061 atgtctttga attagcagaa actggagatg caatagcaaa agaagaagtt gagagttttt
    18121 atacgtatct tacaaaggga ttattcagta ttcaattttc gtttgatcca gaagtgatcg
    18181 tattaggcgg cggggtttct gcaaaagaag ggctcattga tgagatcaaa agccgaatga
    18241 agaagctgac agaacaattc gatctgcatg atttcgaacc gcagatttta ttatgtgagt
    18301 acagaaacga tgctaatctt ataggtgcag cagcaaacta tctcgctgta cgtcaaggag
    18361 agaattaaga gctttagaga aggtgcagct tgcataaaag aagagaatga aatgaatagg
    18421 agatttttac ctaaggaatg ttttatttgc tgcagtatga taaaatatct gagaggtgaa
    18481 aatgatgtca aaaaaaaata aagatattga agtgcgtata gaagaagtga aaaaagatat
    18541 caaaggtaag aattatgaag tcactcagtt atttataggg aaaaaaatga ttggtgagat
    18601 cttagcctat gggccaaaag aatatgaaat tttctttggt gaagaagatt ttggaaaaga
    18661 aaaaagtctt gaaaatgcga tagaaacagt gattcgacac tggaatctgc acgaataaaa
    18721 aaatatcaaa aaaactttca ataaagggtt gcaaaaatct ggaaaattag gtattataac
    18781 taagtcaggt tgatacaaac ctttcggagg agtagcgaag tggctaaacg cgacggactg
    18841 taaatccgtt ccttagggtt cagtggttcg aatccactct cctccatttc attggggtat
    18901 agccaagcgg taaggcaagg gactttgact ccctcatgcg ttggttcgaa tccagctacc
    18961 ccagtatacc acaatcgtaa gctctcgtta gttcgagagc tctttttttt tgctttgcta
    19021 ccttgttcct tgaagattct gctgaattaa gatagagtta agttaactac aagaattgga
    19081 gggatccaca tgaaatggaa agaaaaagta gacgaagcag ctgaaaagtt atatgatttg
    19141 gtcaaatcag aaaaatacaa tattgaagtg aatattccga aaaaaggcgg aaaagcggtc
    19201 caggtaaaat caaaacgccc aacgaatcat acaaaaaaat ggatggctaa aaaccgctaa
    19261 taataacaaa agatccataa gtcggcattt tcatcgattt tagggtcttt tgttattttc
    19321 taggttgaac atatctaaaa aattgtttct gacaatagga gtagggagaa cgatgtgtgt
    19381 ctaaatcctc tgttgatgga tagaaacctt tatctttttc agttgtgaat caggtatata
    19441 ccagttataa tagaagaaac gaaaggacgg gtgtacgtta tgtcgaatca attacctgta
    19501 tatatacaga ttcatgacca attaaaaaat gaaatcgaac aaggtatatg gaaagtcgga
    19561 gaccgtcttc cttcagaaag agaattagca gtgaaattca atgtcagccg tatgacgttg
    19621 agacaagcaa ttcaaaactt ggcagatgaa ggaatcttag aaagaaagat cggttcgggt
    19681 acgtatgttg cgcgagaaaa agtacaagaa aaaatgtctg gtgcaacaag ttttacagaa
    19741 attatggaat cacaaaatcg agtaccgtct agtcggacaa tctcttattt cttgacttcg
    19801 ccaagctcaa gtgaaatgga aaaactaaac ttgagtaaag atgacacgat cttgcgaatg
    19861 gaacgtattc gtttcgcaga tgatgtccct atttgttttg aagttgccag tgttccacaa
    19921 aagctgatcg atggctacag caaagcagag attactgaat cgttgtatcg cacgctagaa
    19981 gaaaaaggcg ggaaaaagat cggtccagcg aatcaaacga ttactgctgt gttggcttct
    20041 gagaaaattg ctgactattt agaggtaaaa cgaagagatg cagttcttcg tttgcgccag
    20101 atttcttatt ttgaagacgg tacgccgttt gagtatgtgc gtacgcaata cgtaggaaat
    20161 cgttttgagt tttatttgga aaaataaaaa acaggtgatc cctgattcct tattagaaat
    20221 aaaagagaat cagaatcacc tgtttttata tatgatcagt tatcagttgc tcgtgataag
    20281 aaacagaacc ctcttcaaat tggacttgtc cgttcagcag ctcaatgatg gattctttaa
    20341 agtggttagc acttttttca tctacagcac agatgacgct aacttgatca gtatattgga
    20401 tttcttttat aaaaaaatgt tggagttcaa gataattctg taattttcct agttgcggat
    20461 acgtgatcat cacagagatc tcctgttgca aggtaccttc tacgattcca atgtcagaca
    20521 atgcttgaga gaccgcatga gtgtatgctc gtattaatcc gcctgtgccg agtttcgttc
    20581 ctccaaaata tcgagtgact actgcagcta cattgatcag ttgatttttt ttgaggactt
    20641 ccaacatcgg tacgcccgcc gttccacttg gttctccatc atcgctgctt cgctggattt
    20701 catttttttc tccaatgatg aaggcgctgc agttatggtt cgctttccaa tgttcttttt
    20761 ttatttcttg aatgaaattt tttgcttggt cctctgattc tattcgtcta agagaacaga
    20821 taaagcgtga ttttttgatc tcaatctcac tttgtccatt ttcttttatt gtacgatagc
    20881 gctcgatcat cttgtcacct ctttttttca ttttctttat tcagtataaa taaagttcta
    20941 ggttgtttca acactgtaac ggttgcgcaa ttgctgtagt atgcgataat aaagacaaag
    21001 gcaggtggat ctggggatgc aggaacgaat gaaaaagtac gatgcaatta cgcattattt
    21061 gaagaacaat ggcggctctc aagtaacgtt gacctttacc caatttgacg aactgctgtt
    21121 tcccagtaac ggacttccca aaacagcaag ggaaagtaca gattggtggg caaatgatta
    21181 taaacaccct gaaaaaggtg cctatggctg gataaatgca ggctatgaag tagttgtcat
    21241 caatttggac aaagaatatg tcgtgttcaa taaattagtg aaatctagtt ggctatttga
    21301 ttaaataaac cgcgtttaga aaacgttgac aaatttcttt ctttttatat aataaagtaa
    21361 cagacgcgaa gaaaacgttt gcgtagtttg ttttaaaaag gagagaaaaa tatggctaaa
    21421 aaaacaatca tgcttgtatg ttcggctggt atgagcacaa gtttactagt aacaaaaatg
    21481 caaaaagctg ctgaagcaaa aggaatcgac tctgatattt tcgctgtgtc cgcttctgac
    21541 gcagataaca atcttgcaaa taaagacgtg gatgtgttgt tattaggccc acaagttcgc
    21601 tttatgaaag ctgattttga gaaacgtctg gaaccaaaag gcattccttt agatgtcatc
    21661 aatatggctg attatggtat gatgaatggc gaaaaagtgt tagatcaagc aatcgcgctc
    21721 ataggtgaat aaatagaaca gtataactat cgaacaagcg atccaaaaaa tagatcgctt
    21781 gttttttcgt atattttttt agggcgaata atatgaatca tttttggggt agaaggcttc
    21841 tgacgagaga tattaaagca atagactgtg aggaggtaaa tttaccaaat tatgagaaga
    21901 tcgcagcagt ggaacgtttg ggcaactgga ttctttgtca tcgctgtgga atgaggacgt
    21961 ccgtcattgt tggacagctt gcagattacg gttatttttg tacacattgt ctatatttag
    22021 ggtgatgcga cactcaacaa gatttatatt tgtttgatca gcctgaagca aaacctcgag
    22081 aagtcgtctt tttttggaca ggacagctta ctgaaaaaca aacggaaatc gcaaagagaa
    22141 tactttgcca ttcagaaaaa agacatcatc ttatttgggc tgtaacaggt gcagggaaaa
    22201 cagagatgct ttatcctatt ttagtggaaa ctttaaaagc tggaggaaga gtagcgattt
    22261 gtacaccgcg agtcgatgtt tgtaatgaat tgtttttacg ctatcgttat gtttttccag
    22321 aagaaaaaat cacgttgctc catgggaata cagcaacggc ttataccttt acttcttttg
    22381 ttatctgtac gattcatcag ctataccgtt tttatcggtc ctttgattta atagtgatcg
    22441 atgagatcga tgcgtttcct tataacgggg atgctgggct agctcacgct gtgcaaacag
    22501 caatcagatc aaacggccga ttcatctact taagtgccac gcctgatgag aagttactaa
    22561 aggaaatcaa gcagacattt gagctccaca aacttgcctt gcgctttcat cggcgcttgc
    22621 ttcctgaacc cgtgcttgtt ttcatgaata attggcgaca aaaatgtgga aacaaaaaga
    22681 aaatcaactc tttggtgcgg atcattcagc aactaatcaa agaaaaccgt atccttttat
    22741 tttgtccaag tattacgatg atgcatcgtt taaaaatcac actgcaagaa gcttttccag
    22801 aatatgagat aacagatgtt tcttcacaag acgatcaacg ggcaaagaaa gttcagaaaa
    22861 tgcgagaagc aatatacgag atactgttaa ccacaatgat cctagaaaga ggagtcacat
    22921 ttgaaagaat ctctgtcatc gttttaggag cagatcatcc agtttttact aaatcctctt
    22981 tggtgcaaat cgcaggaaga gctgatcgta aaggtcctta tacgaacagt cgagtctatt
    23041 ttttctatga agaaaaaact tcagctattc gaaaagcctg tcaggaaatc aaagaaatga
    23101 acgaagaagg gaagcagatg ctgtgagatg tagttgctgc ggtaaagaca tcattcaaaa
    23161 tttaacattc agcgagatca tcggagtgtc gaaatctaga cttcctcaga catgttcagt
    23221 ttgccgcgca caattccatt tattagaagc aaaaggttgt gcaggttgtc aaaaaccaat
    23281 ccatttgaaa tacgaggaga cgaaaaagaa agcaaatact agtttcgttt actgcaacga
    23341 ctgtcaagaa tggaagaaga aatatcctgc atatgatttt caacaccgcg ccttttttac
    23401 gtacgatgaa aagatgcagg cttggatcaa tcggtacaag tttatgggag atatccgatt
    23461 agcagggact tttgcatata aatggactca gataaaaaaa agattacccg gcatatattt
    23521 attgtccaat acctttatct gaaaaaaggt ggctagaaag aggattcaat caagtaagcg
    23581 agatgttgaa agcagcaaaa attccttttc agatgctgct caaaagagag caacatctgc
    23641 ttgctcaagc aaaaaacacg cgaaaggaaa gattggagat gcctcagcct tttgagcttg
    23701 ccgtacctct ttctaagata caacataaaa aa
//
LOCUS       DADVXE010000040        22716 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.041, whole genome shotgun sequence.
ACCESSION   DADVXE010000040 DADVXE010000000
VERSION     DADVXE010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22716
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.041"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            148..1887
                     /gene="yfcC"
                     /locus_tag="KB913_001722"
     CDS             148..1887
                     /gene="yfcC"
                     /locus_tag="KB913_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBB6820083.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2044..3228
                     /gene="iadA"
                     /locus_tag="KB913_001723"
     CDS             2044..3228
                     /gene="iadA"
                     /locus_tag="KB913_001723"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBB6820084.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3339..3542
                     /locus_tag="KB913_001724"
     CDS             3339..3542
                     /locus_tag="KB913_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBB6820085.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3643..4305)
                     /locus_tag="KB913_001725"
     CDS             complement(3643..4305)
                     /locus_tag="KB913_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820086.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4318..5820)
                     /locus_tag="KB913_001726"
     CDS             complement(4318..5820)
                     /locus_tag="KB913_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6820087.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6368..8047
                     /locus_tag="KB913_001727"
     CDS             6368..8047
                     /locus_tag="KB913_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBB6820088.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8174..8653
                     /locus_tag="KB913_001728"
     CDS             8174..8653
                     /locus_tag="KB913_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBB6820089.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8872..9552
                     /locus_tag="KB913_001729"
     CDS             8872..9552
                     /locus_tag="KB913_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBB6820090.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9560..10891
                     /locus_tag="KB913_001730"
     CDS             9560..10891
                     /locus_tag="KB913_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6820091.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10906..11868
                     /locus_tag="KB913_001731"
     CDS             10906..11868
                     /locus_tag="KB913_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBB6820092.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            11979..12317
                     /locus_tag="KB913_001732"
     CDS             11979..12317
                     /locus_tag="KB913_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBB6820093.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12396..13103
                     /locus_tag="KB913_001733"
     CDS             12396..13103
                     /locus_tag="KB913_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBB6820094.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(13206..14687)
                     /locus_tag="KB913_001734"
     CDS             complement(13206..14687)
                     /locus_tag="KB913_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820095.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            14996..15532
                     /locus_tag="KB913_001735"
     CDS             14996..15532
                     /locus_tag="KB913_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6820096.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            15610..16980
                     /locus_tag="KB913_001736"
     CDS             15610..16980
                     /locus_tag="KB913_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBB6820097.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            17047..17382
                     /locus_tag="KB913_001737"
     CDS             17047..17382
                     /locus_tag="KB913_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820098.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(17463..18320)
                     /locus_tag="KB913_001738"
     CDS             complement(17463..18320)
                     /locus_tag="KB913_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820099.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            18426..18941
                     /gene="tadA"
                     /locus_tag="KB913_001739"
     CDS             18426..18941
                     /gene="tadA"
                     /locus_tag="KB913_001739"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBB6820100.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            18964..19048
                     /gene="ffs"
                     /locus_tag="KB913_001740"
     ncRNA           18964..19048
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KB913_001740"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            19258..20643
                     /locus_tag="KB913_001741"
     CDS             19258..20643
                     /locus_tag="KB913_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6820101.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSCLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            20680..21357
                     /locus_tag="KB913_001742"
     CDS             20680..21357
                     /locus_tag="KB913_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBB6820102.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            21365..22129
                     /locus_tag="KB913_001743"
     CDS             21365..22129
                     /locus_tag="KB913_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBB6820103.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            22131..>22716
                     /locus_tag="KB913_001744"
     CDS             22131..>22716
                     /locus_tag="KB913_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBB6820104.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLL"
BASE COUNT         7389 a         3819 c         4852 g         6656 t
ORIGIN      
        1 tcatacatag gagaaaaaaa acaaaataga aaaaagtgat tttctaataa attattcatg
       61 tggaaatgtc atttttactg tataattcat ttgattatcc attttttatt catcaaaatt
      121 actgaaaaaa gaaaggaaga aataaatttg aagaaaacaa attcttcagg aaaaccgaaa
      181 cgcgacttca ctaaattatc gacaccccat acgtatgtca ttatttttgg tgtagtcatc
      241 tttgcatgga tactgacttt tgtcgttcca gcaggaaagt tcagcacgca agatattgaa
      301 tacaaagatg caaatggcga aacaagtact cgtactgttt tacgtcaaga ttccttccgt
      361 tatgcttacg agctggataa gtcgtatgtg tttgatcaat tagaagaact gcaagatcat
      421 ccagcagaac gtgaaaaact ggatgttccg gaaaaaggat tggaaaaagt cattgctgac
      481 ggagaaaaaa atcttacgca ggaaaaacta gatgaaatct ccttgacaga tgatgtgctt
      541 tacgatcagt acggcgaaaa tatctatgat acttctaaaa aattgcataa aacagccaaa
      601 atatggggaa cagatgattt tggcggcttt ggtttcttaa attttgtttt tgaaggacta
      661 gtatctggag ataagtatgg atctgctgta gggatcgctg cattgatcct tgttgttgga
      721 ggtgcttttg gtattattat gcgtaccgga gcgatcgacg caggtatcta tgcgtttatc
      781 agtaaaacta agggactgga gcgtttagct ttaccgctat tattctttgc tttttcattc
      841 ggtggcgcta cattcgggat ggcagaagag gtaattccat tctcaatggt gatggttcca
      901 tttgtcattg cgttaggata tgactcgatc gtagcagtaa ccgtgactta tgtcgcatct
      961 caagtcggaa atgcgacctc ttggatgagc ccgtttagcg tagcggtggc tcaagggatt
     1021 gctggaatcc ccgtgttgtc tggtgcgaca ttccgattga ttatgtgggt agttgttact
     1081 gcattagccg ctggttatat gatgatatat gcagaaaaaa tccgtaaaaa accagaaagt
     1141 tcgttgactt acaaatcaga tgattatttc cgttctcata tcaaaaagac atctgatgaa
     1201 aataaaaaat tcatgcttgg gcataaattg atcttattag agatgttagt tgtccttgtc
     1261 tggatcgttt ggggcgtgac tcaaaaaggc tattacattc cagaaatcgc ttctcaattc
     1321 tttgtgatgg gattagttgc tggaatcatt gctgttcttt tcaaattaga tggaatgaaa
     1381 gtcaatgaca tcgcttcttc tttccaatct ggtgcagctg atttagctgg tacagcaatc
     1441 gtagtaggta tggccaaagg gattcttctt gtcttgggag gatctgatgc atctgttcct
     1501 tcagctttga atacgatttt gcatgggatc gggacggcgt tgaccggtgt tccagctgtc
     1561 attggtgctt gggcgatgta catcttccaa agtttgttca acttggttgt tacatcaaat
     1621 tcaggacaag cagctttgac tatgccaatc atggctccac tggcagattt agtaggtgta
     1681 tccagacaag tagcagttct tgcttatcag cttggttcag gttttatgga cgcttttaca
     1741 cccgtatcag ccagcttgat tggtgtgcta ggtgttgcac ggatcgaatg ggcaaaatgg
     1801 gcaagattcc aaatcaagat gcaaggattc ctgtttgttt taggaactat tttcatcatg
     1861 attgccattg caataggtct gcagtagtac tggagacctg taaataaaaa agtaatccaa
     1921 acagtagata aggactccaa gaaccgtcat tttacggtaa aatcaaagga gtaaagatcc
     1981 tatcgtttgg attatttttt aagatcctat catcagttat acttaaagaa agaggaaaaa
     2041 tgtatgaaaa tcattcgaca aattgaagtg tttgcaccag attacttagg aaaaatggat
     2101 gtactgattg ccggtgggaa gattttggct gtagaagaac agctagaagg cggctacgaa
     2161 ggagtggaag tagaagaact ttcaggtgag ggaaaagtac taaccccggg tttcattgac
     2221 tgtcatttcc atattttagg tggaggagga gaaggcggtt atcaaaatcg aacgccagaa
     2281 gtcacattga gccaattgac tacagctggt gtaacgacag ttgtcggttg tttgggaaca
     2341 gacggagaag gtagagatat gactgcgttg atcagcaaag cgaaaggtct ggaagcagaa
     2401 ggaatctcca cttatgtata cgaaggttcg taccgattgc cggtaaaaac agtaacagat
     2461 tctatcatca aagacttttt gacaattgat aaaattatcg gaatcggaga aatcgcagta
     2521 tccgatcacc gttcttctca gccaagtttt gaagagttcg ctcgtgcagt agcagatgct
     2581 cgtgtaggag gcatgttatc cggaaaagct gggatcatca atgtccactt aggcggagga
     2641 aaaagaaagc tagagctatt gacacgaatc gtagaagaaa cagaaattcc gatcacacaa
     2701 tttttgccta ctcatgcaaa tcgcacacca gaattatttg aagcttgcgt ggcatttgcc
     2761 aaacgtggtg gcacgattga cttcactgct agcgaagatc ctgatttttg ggagaagaca
     2821 gatggtgaag ttcgcttcag caaagcactg aaacgattga tcgaggaaga tgtttcttta
     2881 gataatttca cgatgacctc agatggacaa ggaagcttgc cttattttga tgaaaacaat
     2941 catttcctag ggttaggagt aggaagtgcc aaggcattgc tagtagggat caaagaagct
     3001 gtgcaaaaag aaagtatccc tttggaaatc gccttacgag ctataaccag taatccagca
     3061 cgtatattga aattggataa aaaaggaaaa atcgaaattg gtgctgatgc agatctgtgt
     3121 atcttggata aagaaacgct tgatattgat acagttatcg ctaaaggaga aataatggtc
     3181 caagaaaaag aagtcaaagt atgggggact ttcgaaaaaa gtttttaatc aacagctcta
     3241 actatctttt ttagaaaacg agcgttctgt ttgtctgtat ctgttgttga tgttaccctg
     3301 aaggtagatc aataaacaaa ctaagaggag gaagcacaat ggcagattta aaaggacgtt
     3361 ctaaagatat gaaagataaa gtagtcggtg aaggaaaaga agcatacggc aaagcaacag
     3421 acgacaagag caaagaaaca gaagggaaag cacaatcact aggtgctgac atcaaagaaa
     3481 aagctcgaaa tttaggcgac gaagtcaaag acaagttttc tcgaaaagac gaaaaaaaat
     3541 aaaaaccact tattactaat tgaatcaagc aaataaaaaa tccgaaccat atctgcgaga
     3601 cagatatggt tcggattttt tatttgatca ttatcctgtt ttttaaactt cgattttttg
     3661 aaatttttta ttttttagtt caaagacttc atcacagctt tttgctactt caatctcatg
     3721 agtcacgatg ataatacagc gattttgttc atgggcgatt tcttggaaaa gtttgacgat
     3781 atcttgtgaa gttgtttcat ctagatttcc agtaggctca tccgctacga ttagttgatg
     3841 ttcacagcag atagcacgaa cgatagcgac tcgctgctgc tgacctcccg aaagtttggt
     3901 cacctgtttt tttgctaata tttcatcaat tcctacacga gccagtcgat ctaaagcaac
     3961 ttgtcgataa ttctcttgct tggtcttagt gatttccatt gctgctatga cgttgtctag
     4021 agccgataaa taaggaagca agttgtaagc ttggaaaata atcgagacat catttttacg
     4081 ataacttctt aacccgattt tgttcagtga acgatcttga tagtatacct ttccttcttt
     4141 tggtgcatct agtccagaaa taagcgaaag aaaagtcgtt tttccagaac cacttgctcc
     4201 taaaatagcg tacatttttc cagcttcgaa attcagttct acatctttat aaagcgcatc
     4261 ttgcggatct tgataccaaa atcccaattg ttctgtccgt aacatcaaat tcctccttta
     4321 gtttaatagg atttttcttg ggtttaatct taatatccct atagaagcta aaaagacaga
     4381 aaacagactg attccaaatg ctactccggc taatagtccc aattgtgcag gtttgacatt
     4441 gatttccaat tcgctgactt gatcagaaac agcaaatgga ttattcgtgg ttccttgttg
     4501 accatcgcgt tgaccgcctt gttcttgtct gttacctggc atttgtccac cgccaggagc
     4561 ttgctggttt tgtgtcgtgg tttctgtctg ttggtcaagt agctgctgtc ccacggcatt
     4621 cgcgacgacg tttccgctaa gcgaagcaac tcctaatgca agaatcatac aaatagccac
     4681 ttcggtaaac aattggagaa tgattttact tctggattct cctaaagata gcaagacgcc
     4741 taactcatgc cgacgctccc gaatggtaat cataatgatc agagtaagta tgataatacc
     4801 ggctacagcc actagtaaaa caacattttt agaaaaactt gccacgttgt ttaaaggttc
     4861 caacattgac tgatacatgg aatcatttga ttgtaagcta aatgtatctg tgtcgatcag
     4921 cttctcagct tctttgagaa actcatccat tttatctgga tcagatagag tgtaaatagc
     4981 agaatctatc gtgttatcgt cagatgtccc atttagttca tttgcaaaag tgtaagaagt
     5041 gtaaagtgta ttcgacggat tcatgaagtt gaatttcata cccatactgc cgcttgtttc
     5101 gctggattca taaattcctt tgatcgtcat ttcataagtg gtatcttcat cttcagtact
     5161 cgtgattgtg aaagtatctc cgactgccag gtcatttgtt tctgctagag tagaatcaat
     5221 gactacattg tttgtgcctt tgtcgctgtc atctattcct tcaccatccg tgatttttgc
     5281 tgttccatca gaaaaattac tattttgtgc agttgctgac acaccactga tttgaaagtc
     5341 tgcttgagtc atttgcggat tcccgcccat tcctccagca ggttcaccgc ctgcatcagt
     5401 agtttctgaa ctgtcttcac ttgaatcaga actagtgatg gcagttattc catcttttgc
     5461 catagctgag gcggaacttt caaaggaata actctttaca ttatctaatt cagctatttt
     5521 ttccgcgtcc gttaaggaaa ctggtgtaag agaaaaactg cctggatctg gacgttcttc
     5581 agtggtagaa ccgcttgaag aagtttgttc ctgtttttta aatgaagctt ctcgattggc
     5641 acttaaagtc actgttgctc caacttcttt ttgtgcttga ttcgctgctt cttctgcagc
     5701 gcttcgaatc gtgaggccag ctagcacaaa aataagaatg gctgtgaaca cggcaaacaa
     5761 taacaatgaa cgtccccatt ttacttttgt acttttccat gcacgtttca taaaattcat
     5821 attttgcatc cctcctagta gatgcatttg ataatagaca acctatctta aagctagctt
     5881 aaatcttatg ctgtttgcac accatcaaca tgaggttctg tatatataaa aagtcactat
     5941 agttattgca aaaaatgtgg taaaatgaaa aaagtatgtt tcaaaccgac gaagaagaaa
     6001 tgaaagagga atagcaaaag aaatcctaga tgctacagag ggatttttac gtgcatagtt
     6061 gttctaacaa ttgctgatac tagcgattta gtttatttgt tgtataataa tggggaacag
     6121 ctgaatactt atataagtat tctggctata gcgtttcgca aaagatccat tttgttaatg
     6181 aagtatatcc aaaataaaat gcccatccaa ctgtcagaac gcggatgtgc tggtaatttt
     6241 cctgctgatt ctccataagt tgagaaatag tgattttgca tatgcttcat tggaatggct
     6301 catatattta gataaagaag aaaatcgaca tctttaaact tggatgtcat aagaagaggt
     6361 gaagtttgtg agtaccatta aaattatccc attaggcggc gttcgtgaaa atggaaaaaa
     6421 catgtatgtc gcagaagtgg gcgaggatat ttttatttta gattgtgggc taaaatatcc
     6481 tgaaaatgag ttgttgggga tcgacgtcgt aatccctgat tttacgtatt tagaagaaaa
     6541 cattgatcgt gtagctggtg tctttttaac acatggacat gcagatgcga tcggggcact
     6601 tccttacttg ttgtcaaaaa tttctgtacc agtattcggg acagagttga cgatcgagtt
     6661 agcaaaattg aatgtcagtc gtaatgaagc agccaaagga tttaaggatt tccatgtggt
     6721 agatgagcat acagaaatag actttggtga aacagtagtg agctttttcc gtaccactca
     6781 tacgatacca gattcagtgg ggatcaatct gaaaacaaaa gaaggtagta tcgtttatac
     6841 gggagatttt aaatttgacc aaacggctat cccaatgtat caaacagatt atgcacgatt
     6901 ggcggaaatc ggcaaagaag gagtcttagc cttactaagt gaatcggcaa atgcagaaaa
     6961 tcctcagcct gtagcttctg aagcccaaat agcagatgaa gtatttgata cgatcaaata
     7021 ttgggaaggg cgtatcatcg tcgcttgtgt agcaagtaat ttgcaacgag tgcaacaagt
     7081 attggatgca gcagaaaaag cacaacgaaa agttgtcttg actggtcaag atttcgaacg
     7141 aattattcgc acagcgatgc gtttagaaaa acttcaatta ccaagtgaag atctgcttgt
     7201 tacgttgaaa gacatgaaaa actatgatcc agaagaactg atcattttag aaactggccg
     7261 aatgggtgaa cccatcaagt ctctgcaaaa aatggcaaac ggtacacacc gtaatgtcaa
     7321 gattgaagaa ggagatttgg tttatatcac tactacgcca agcatcgcga tggaaaccat
     7381 cgtggcgaaa acggaagata tcatttatcg agctggtgga acagtgaagt tgatctctga
     7441 gaatatgcgc gtttctggcc atgccaatcc taatgacttg caattaatga tcaatttgat
     7501 gaaaccaaca tattttgtgc cagttcaagg agagtatcgt gaattagctg ctcatgcaga
     7561 tttggctcat gcagtaggga tgccatacaa aaatatctat attactggac gcggagacgt
     7621 gctggaatat aagaacaagc gtatgagtgt tgcaggaact acaagtgcag aaaatgtaat
     7681 gattgatgga ttaggcatag gtgatatcgg aaacattgtt ttacgtgatc gaaaaatctt
     7741 gtcagaagac gggattttcg tagcggttgt cactatcagt cggcgagaaa agaaaatcat
     7801 ttcaaaacct caaattactt cacggggatt cgtttacgta aaagctagcc gtgatctgat
     7861 gaaagaaagc agcaatatga ttgaaacaat cgttgagaaa catttagaaa gcaatgattt
     7921 tgagtggagc aaattaaagc aagacatccg agatcaatta ggccgttact tatttgaaca
     7981 aacaaaacgc cgcccagtga tcttgccagt cattatggaa gctactcaac gtcgaaataa
     8041 aaaataaaca aaaagagtaa gatgaacctc tctatagagt gctcgtcttg ctcttttttt
     8101 gcgaaaaaca aataattttt gaatacagca tccctcgctt tataataaac gatagaataa
     8161 agggagtgaa tcaatgatga gtcaaacaaa agtcgaacgt tatttagaag aacaaaagat
     8221 cagctatcaa ccacttgatt ttagtcatgt ggtagaagaa tctttcacag aagaactaca
     8281 aaaaagaggg attgatccag ctttgatatg taaaactctc gtagtgaaag gaaacaaaac
     8341 tggggtgatc atcgcattga ttcctttgaa cgatcactta gattacaaaa aaacgagaca
     8401 agtgacgaaa gatcgtaaag ttggttttcc tggaatggat tttgtattaa tgcatacagg
     8461 atatccccac ggagcaaaca cccctattgg aataaaactc gcacatcctg attattgttt
     8521 tttagcagac agttctttaa aagaaaaaga agaagtaatt gtgtcaagcg gtgaaatcgg
     8581 gagaagcctt cggataaaag tagccgattt agaaaagatc gtccatccta tttacgctga
     8641 tttaattagt taagggacga gaagagaagc taagcagagc agagacctca aacttgagat
     8701 tatatctgct tggtacttgg tgcatcctgt attatctgtt acaattgctt tgtacatact
     8761 gtactatcaa tccaatgaaa atatatttag cagctatatt ttttcattga tgtgcaagtg
     8821 atgaaatcgt ttttaataaa aaagatacag agaaaacgcg aggtgtaaaa tatgaaaatt
     8881 acgtatcatg gacattcctg tttaacaatt gaaatggaaa atggccaacg cgtgatgatt
     8941 gacccgttta ttacaggaaa tccattgaca gacttaactg cagaagaagt aaagacagat
     9001 tggttgctga ttactcatgg tcatagtgac cacataggag atatgattcc tattgcaaaa
     9061 gaaaatcaag ccacaattat cagtattgtt gagattgctg attatgcgaa cagcagagga
     9121 gtagattcat tcggtatgaa tatcggtgga aaacatgcgt ttccattcgg cgtggtaaaa
     9181 ttcgtacatg cacagcatag ttcaagctat gaagtagacg gtatcgttca gtatatgggc
     9241 gagcctagcg gaattattat tcaagcagaa ggaaaaacga tttatcatgc aggggatact
     9301 gcttatttca gtgatctagg attgcttgca gaagaattcg atattgatgt cgctttcttg
     9361 ccgattggcg ataactatac gatggggcca gaagatgcag caaaggctgc gcaaacaatt
     9421 cgtgccaaga aagtagttcc aatccattac aatactttcc ctgtcattga acaagatccc
     9481 gaatcttttg tagagttact ggaagatagt gaaggaaaaa taatgagcgt ctcggaaacg
     9541 ctggaagtgt aggcagaaaa tggcgacaaa acatgatttg attttagaat atattgaaag
     9601 tttacctgtt ggcaatcgaa tttctgtaag aagcatcgca aaagaattga atgtcagtga
     9661 aggaacagcg taccgtgcaa tcaaagatgc agaaaatgtc ggactagttt caacaattca
     9721 acgagtaggg accatccgta tcgaacgcaa attaaaaaaa catattgaac gtttgacatt
     9781 tggcgaggtc gtcaggatca ttgaagggga cgttttaggc ggggcggcag gattagacaa
     9841 ggtcttgaat aaattcgtca tcggcgcgat gactaaacat gccatggaac gctatattac
     9901 gccaggatca ctaatgatcg tcggcaaccg ggcggaagtc caaaaattag cattggaaga
     9961 tggcgccgca gtattgatca caggaggatt caatacgact gctgagattg caaagctagc
    10021 tgatgatctt gaaatgccga tcttacgcac ctcttatgat acatttacag tcgcaaccat
    10081 gatcaaccga gcgttaagcg accaattgat caaaaaagat atcatgcttg tcagtgatat
    10141 ctatatgcca gctgaaaaga ctcattattt gcagcagaca gatacgattt ctgattatca
    10201 gcgtttgtca gaagaaacgc agcattcgcg ttttccagtc gtcaaccgcc atcatcgttt
    10261 gatggggatt gttacggcaa aagatgtttt agggaaatcg ccaaaccaga tcatcgatcg
    10321 ggtgatgacg aaagaaccaa tcagtgtaaa gaaaacaatg agtattgcct ctgttagcca
    10381 tcaaatgatc tgggatgggc tagaagtcat gccggtcgtt tccgatgact tgacattgga
    10441 aggcttgatt acccggcaag atgtaatgaa agcgatgcag cttgtccagc gacaaccgca
    10501 gattgcagat acgatttcgg atcagatatc tggaaatatc catacgattg atactgaccg
    10561 tgaaggaaat cgtttggaaa accctaagtt caaattcgta gtagcaccac aaatggtcaa
    10621 tggcgttgga accatttctt ttggcgtact tagcgaaatc atttctgatg tcgcacaaaa
    10681 aacaatggtg atgaaccaaa aacgaaatat cttgattgaa caagtgaacc tacattattt
    10741 gcggctgatc caattggaaa gcgaattaga cattcgtcca cgtgtattgg aaatcggcag
    10801 acgttccgct aaactggata tcgaagtgtt tattgaaaac accatcgttt ccaaagcaat
    10861 cgttgtttgt caagtaatgg aacgttctta gaaagcagga gtgaaatgac agtacagcaa
    10921 gaaatagtag atacaataaa aaaatacgat aaaatcatta tccacaggca tttgcgccct
    10981 gatcctgatg cattaggatc acaagtagga ttagccgaac tattacggga aagtttccca
    11041 gaaaaagaaa tacgtcaagt aggtgaaacg attgaagggc ttcgcttttt agcagaaatg
    11101 caagaagttg aagatgtctt ctaccaagga gcgctagtca tcgtgactga tacagctaat
    11161 tcacccagaa tcagtgatca aagatatcag ttggcagaaa aactgatcaa aatcgaccat
    11221 catcccaatg atgaccctta tggagatctt gtgtgggtaa atacaaaagc aagtagctgt
    11281 agtgagatga ttgcagaatt tgctttgatg tttcctgaat ctttaaagat gaacgttaag
    11341 gctgcacggt tactttatgc aggaatcgtc ggagatacag ggcgcttttt gtatccctcc
    11401 acgacgtccc gtacattaga gattgcttcg atattgagaa attatccatt tgatgcaagt
    11461 gctttgaaca gagagattga acaaatgccg atgaaagtcg ctaaactttc cggttatctt
    11521 tatcaaaata tccaggtgga tgaaaatggt gcaggaagaa taatccttcc gcaagaaatt
    11581 cttgataaat atggaatcga tgattcagag acagcttcga tcgtttcact tcctggagtg
    11641 attgacgaag tgctggcttg ggggattttt gttcagcagc cttcagggta ttaccgcgta
    11701 cgtttacgtt ctaaggggcc gatcatcaat gaattggcta aacgccatca tggaggaggc
    11761 catccattag caagtggtgc gaatgcaaaa gatttagcag aagtagagga aatctataaa
    11821 gagatccaag atatatgcca atcgtataag agcagaaaaa cagaatgata cttcgttcga
    11881 aaacgtgcct tttgtagtaa aaatcacaaa tgtatctttt caagatcttc tttttccgtt
    11941 acaatagtgc tcactaaaga ttttaaagga gaaagaagat gacattacca aattgcccag
    12001 aatgtggctc agagtacaca tatgaagatc gaggcttgtt gatttgccca gaatgcggga
    12061 acgaatggaa caaagaagaa caagaaactg tcatagaaga cggattagtg gtattagatg
    12121 caaatggaaa ccgtctgtta gagggcgata gcgtgacagt gattaaagac ttgaaagtaa
    12181 aaggtgcgtc aggtgccatt aaacaaggaa caaaagtcaa gaacatccgt ttagtagaag
    12241 gcgatcataa tatcgattgc aaggtagaag gatttggacc gatgaaactg aaatcggaat
    12301 ttgtgaaaaa gaattaaaga atattcaagg tcttttcaca ttcttttcct actactaatg
    12361 ataaaataaa gtaaacgaaa aggagtgaaa cgaaaatgta tggttatgga atgtatggtt
    12421 ttttagatcc gacatttctt ttggtcattc ttggattagt tatttccgga attgcgtcag
    12481 cgtacgtcaa tagtactttc cgaaaatacg atcaagtgag aagcaaaaac aatgtgactg
    12541 gtacacaagc agcacaatat atattacaaa gtcaacagat aaataatgtc ggtgttcaac
    12601 aaattgccgg agatctcaca gataactaca attcaggtaa taagatgttg agtttgtctc
    12661 aagcaactgc acagtctact tcagttgctg cgataggtgt agcagctcat gaatgcggac
    12721 atgcggtaca agatgcttcg ggttatgtcc cattgaagat tcgtgcagca cttgttccag
    12781 cagctaactt tggttcgatg atttcgttcc ccttgattat ggtaggtgta ttgcttagct
    12841 ggaactctac gttaatcaat atcgggattt tcgctttttc tttagcatta cttttccaat
    12901 tggtgacatt accagtcgaa tttaacgcgt ctcggcgagc aatccaaatt ttgagtgaag
    12961 gcggactact gacggaagaa gaagtaccga tggcaagaca cgtattattt gcagcagcac
    13021 tgacttatgt tgcagcagcg ctttcgacat tcctgcagct gttgcgcttg atcttattgt
    13081 tcggcggcaa ccgaagagat taaaataaag aagttgtgaa atcagcgctt tgatctgagc
    13141 taataccgag agttagctga ttgaatacca tttatttgga ataagaggat gtgacaagaa
    13201 ttttgtcaca tcctctttgt tttgttctca taaccttttt tcatatacag ttcatgaacc
    13261 gcttttatta acttgccaaa taacactgta ttgtgcgttg tatccagata gaaagtctcc
    13321 gtttcatctg aaattttctc atgctgatct gtaatgatca aatcagcatg ttctgaatat
    13381 gcggtaattt taacagcatc tttgcgaaat aactgctgca aatggctttg aagatgataa
    13441 tttcctgtaa actgtttggt tatctgcaaa tggatgagta actgctcttt cgtttctgtt
    13501 tgtagtaagt gttggatcaa ttgactaagg tattgactga tttggtttct ttccccattt
    13561 tttgaaaaaa ttgtatcgat tttttctctt aatttctttt cctgtataaa agaactagaa
    13621 tgattggacg tggcttctgg aaagcaaagt gtagaaaaac tactgctgga ttcacccaac
    13681 agttcgaaaa aaacaactgc caacacaaga aaataaaaat aaattggtat tttattttct
    13741 aaatggttga gaggaaactg ttgagttaag taagtcatca attgaccgac ttgtcgacaa
    13801 ataaggtttt tgcttgtgga aaataaaaaa ccaatctcct gtttttgtcg aaaagagatt
    13861 tgatttggaa aaaaacaata gaaaaaataa ttaaagtagg ctctctctgt ttctgtctct
    13921 tcacaagggc gactcactga aaaagaagta aagtattctg aataatcatg tgtatgctgc
    13981 aataagtcca tcaattcagt gatttcagaa gaagtttttg gaaaatatgc ctgttgtttg
    14041 tttcgtaata tgaataaagt taacagcaag tagatatttt tttcttgttt tgaaattttt
    14101 tctatttgct catctgtact gttcattttt agtgcattta attcaagtga ggaaaatggc
    14161 caatcgttac ctccaaatgt atctgaaaga aaaaagtaaa gatagagacg gatagataac
    14221 tcatttcctt caagagtaca gcaatttttt acagatagga tccgtaaatg gaattttatt
    14281 aaggaatgat tgagctgttt tgtcagtttt tcgagatagg agggcgatat ataaagttgt
    14341 tcaagtaaat atttttttgg tacagcagtt tgtggataat tgattagtaa catcaaatag
    14401 ttaaaacgat tggattcttt taggtagcat aattttaact tagaaaaaac agctaacttt
    14461 ttagtttgat cggtttcttt ggtttggatc tctcctttat gattagaata aataaattca
    14521 tcaatcaata aaaattgctt gagtgataca tttatttttc ggatcagttc tttgattgtc
    14581 cgttttggaa tatgtaagtc attggataat tcttgtaaag aacaattatt tttttgaatg
    14641 accatttgta gaacaagtaa ctcttttttt cttgcttcaa ttagcataaa tacctccttt
    14701 ttattctgtt tttgtatata gttagacaaa aactgtgagt ggaaagtcat ttcagtctgt
    14761 gttattctca cagagtgtcg ccttcttttt tatataacgt tatttaattt ttttgttacc
    14821 ttgtttattc tattgtttat ttcctagggt attttgtcaa gatattcttg tttttaaggc
    14881 ggaaaaattg atttttaatg gatataacta aatatgtttt gataattatc aataatattt
    14941 ttagaattat ttatgttatt tatttatggg tagatgaaaa gagacggagg taagaatgat
    15001 ggggagagta acaaattata gtaaagaata tttgctgttc aaaagtatgg tatacgtgga
    15061 agaatatgga atgaagtcaa ttactgcaag agagttagca gagttctgcg gttgttctac
    15121 atacccgatt tatacacatt tcaaatcaat cagcgggtta aaagagaaga tattagaaga
    15181 aatcactgtt tattttgaaa actacttagc tgaatgcagt tccgatgatg ttttaagcat
    15241 tgtctactta ttgaaagatt ttttttctat ccatgaaagt attcgtgaaa tcattgcaaa
    15301 atctgattta gacatggatt cgctatttaa gcggccattt ttctcatatg tcaaaggtca
    15361 cacgaagatc aaagaagaaa agtcgcttga attggtatgg cttaatgcat tgggaagttt
    15421 gcgctcagat gattcttctc aagattttct tgaaatgatg aacgctgttt gggataaaaa
    15481 cgaggtgacg gatgaatact tggaaaatat cttaaaggaa cagtcacctt aggcagcaac
    15541 atgaaaaagt agatcagcca cctttatttt tcgtaaaaaa gattgtaaaa tgtctaacga
    15601 aacattggaa tgaaggagga agcgacaacg ttaccacagc aatttatcaa aaaatatcgt
    15661 cttcttttag gcgaagaagc atccgatttt ttttctgcgc ttgaacaagg aagcgtgaaa
    15721 aaaggatttc ggtggaatcc actaaaaccg gcaggattgg acatggtcca aacttaccat
    15781 agcgaagaat tacaacccgc tccctacagc aatgagggat ttcttggcac tgtcaatgga
    15841 aagtctttcc tccatcaagc tgggtatgaa tatagccaag aaccaagtgc aatgatcgtt
    15901 ggaacagctg ctgcagcaaa acccggtgaa aaagttttgg atttgtgtgc ggctcccggt
    15961 ggtaaatcaa cccaattagc tgctcaaatg aaggggaaag ggttattagt gacgaatgag
    16021 atctttccga aacgtgcgaa gattttatca gaaaatatag aacgatgggg agtttcgaac
    16081 gcaatagtga caaatcatgc acccgcagaa cttgtccctc atttttcggg cttttttgat
    16141 cggatcgtgg ttgatgctcc ttgttcagga gaaggaatgt tccgaaaaga tccaaatgca
    16201 ataaaagagt ggacagaaga atctccgcta tactgtcaaa aacgtcagca agagattttg
    16261 tcttcagcaa taaaaatgct aaaaaataaa ggacaactga tttattcgac ttgtacgttt
    16321 gcaccagaag aaaatgaaga gatcattagc tggcttgtag aaaattatcc agtaacgatt
    16381 gaggagattc ctttgactca atccgttagt tcaggacgtt ctgaatgggg aagcgtagct
    16441 ggtttggaaa aaacaatacg tatatggcct cataaagatc agggtgaagg acattttgtt
    16501 gcaaagctga cttttcatgg acaaaatcag atgcataaag aaaagaagac acgaaaaaaa
    16561 agtaaagtgc aaatgacaaa agagcaggaa aaactctgga cggagttttc aaatgatttt
    16621 cattatgaag ctactggaag acttttagtg ttcaacgacc atctttggga agttcctgag
    16681 ttagcccctt ctctcgatgg tttaaaagtc gtacgtacag gtttgcattt aggagatttc
    16741 aaaaagaatc gatttgaacc tagctatgca ttagcgcttg ctacaaaaaa gatagagaat
    16801 ataccttgct tgccgatcac tcaaaaggaa tggcaatctt acacagcagg agaaacattt
    16861 caacgtgatg ggaatcaagg atgggttttg ctagtattag ataagatacc tgtcggattt
    16921 gggaaacaag taaaaggaac agtaaagaac tttttcccta aaggattgag atttcactga
    16981 gtggattagt tcgtttattt ttttgtctat gctatgatgg agatagataa aaaggagctg
    17041 atacttatga aaacatcaac aaaagtaaca atcggattaa gcgtagcagc cgctgccagt
    17101 gtagcgacag cagtcgttgt atcgggaaaa gtaatggaaa agatccatca tatgactact
    17161 cggacgaaag taaaaaaatt cgtctatgac aaatttgatg gaaatgaaaa attactagaa
    17221 atcgtagatg gtctttcaga tagtgacttg gattctttga tgggaatgtt agcaaaaatc
    17281 aaatcaggaa aaaagaaaat ctctgtttat ggtgattcaa tcaaagattc aaccgaagat
    17341 gtaaaagacc ggctaatgca ttttgttgaa aaaatgatgt aagagaaact agcttttgaa
    17401 cactattcat tcgaaataag gggttgtgac aaaattattg tcacaacccc tttaatctat
    17461 ctttaattat gttcatgaag caataaaaga tagcaaaaca gtaaatcgtt ggcttttttt
    17521 agattgaaac cagactgttc ttgaaatttt tcgattcgat attttagagt attacgatga
    17581 agaaacagtg tttttgcagc agagctgaca ttgcctaatt cattccataa ttcttgaatg
    17641 atcacttcca tttcattttg tttgatcagt tctatgtaac ttttgatcaa cttactatct
    17701 tttacagtat cttttgtata gtaatgtaaa gccacatctt gcatagaaaa agtacggctg
    17761 tgagtataaa gattgttttg ctctgttaaa aaaatttttc tttcttcagc aaacaaaggg
    17821 acgaggtcgg tgccaggtga atggaaagaa ccaacgaata cagacgttgt cgtatcaaaa
    17881 tcagcatcta aagatagaaa aataccgttg atttcagtag catcaagata atcacggttt
    17941 atttgttcga ctaagagcgc atctgtgtct gtataaaaaa agaaatcagc agaatagcga
    18001 aataattcca aaatagtatc ttgccattct ttttttaaga attctccttt tgattcgacg
    18061 tgaagctgga tcaaacgaaa gcttttttct tgaacacaag aagcatcttt aaaaagatag
    18121 tgataccatg ggtgtttttt ttgatcgttg attacaggga ataacgcttt caaaaggctg
    18181 gtttcttgtt gagataatga atcttgtttg atccagataa aagcatcatc aattgcaaaa
    18241 gaaaggatat ccgcttctga tgctggagag ttttttttct gtgcttgtgg gtaaagagca
    18301 agtaatttat ccattttcat cttgttcacc tcttgtattt attttaccat agaaaaaaag
    18361 ttagttacag cctttttatc atatgctaaa gtaaaacaag aaaaaacaaa ggcagggaag
    18421 ggtaattggt aaatacaaat cttgatgcag tagaaaaaga aaaatggatg cgccttgcat
    18481 tggcagaagc aaagaaagca gaaatgcttc atgaagttcc gattggagca gtggttgtat
    18541 tggatggaaa agtgattgga agaggatata accttagaga aaccacgcaa gatgctacta
    18601 cacatgcaga aatgcttgca atcaaggaag cctgtgaaaa agtgggaagc tggcgcttgg
    18661 aagatgctgc actttttgtt accttagagc cttgtcctat gtgcagcggc gcgatgattt
    18721 tgtctcgtgt agcagaagtt tatttcggcg cgtatgatcc aaaaggcgga acagccggta
    18781 ccttgatgaa tcttttggag gacgagcggt ttaaccacca agcatatgta gaaggtggca
    18841 ttttagaaga cgaatgtggg atgattttga ctgacttttt ccgaaagctc cgccagcgaa
    18901 aaaagaaatt aaaaaaagac tggtcaacga atgaaaaata aggtatacta ttctttgccg
    18961 aaaggctagg acaatggtgg gcttgtgaag cgtgtcaggt ctggaaggaa gcagcactaa
    19021 gcaggttccg ccatgtgtct gattataatg aaacgacaac agactttcgg gtctgttttt
    19081 tttattttta tagtactgta aaaatgaatg ttcctgattt tttagccaga ctgatttatc
    19141 gaatattgta cttatacaat ttgcttcaag gcaggaaaaa ctctgaaata gagcttgttt
    19201 caatggaaga aaaagctgcc tatggtatga taaagataaa gagaggcgag agggtacatg
    19261 gaaaaaatag tgattttaca tacgaatgat ctgcattctc atttagaaaa ttggccaagg
    19321 atcagaaggt ttttggatca acgtaaacga gaaaacgaaa agaaagaaaa aacgacaacg
    19381 attgcagtag atctaggtga ttttgtggat cgttggcatc cattgtcaga agcaacgaat
    19441 ggacaggaaa atatcttgct gatgaatgaa gttggttatg atgcagcgac gataggaaac
    19501 aatgaaggcg taggaaattc caaagaagag ttgaatcatt tatacgatca tgctgagttt
    19561 gatatcatcc tggataactt attcgataaa aatacgctcc agccaccggc atggacgaaa
    19621 ccatataaaa tcattacaac gaaacaccag acgaaaatcg gactaattgc atttactgct
    19681 ccatttccgc ttacttataa tccgaatggc tgggacatac ggaatcctta tgatattttg
    19741 ccagaattag tcgaagattt acgttcacaa gtggatgttt tagttttgat gagtcatctc
    19801 gggattcagg atgatttcca aattgcaaaa gaaataccag caattgatgt tattttagga
    19861 tcgcacaccc atcatttatt cagagaaggt cacgtaatca atgatgtcca aatagcagcc
    19921 gctggaaagt acgggcagta tgtcggtgaa gtccatttaa ccatcgatga agagaaaaaa
    19981 atccttaagc attcagccaa agccatccct accgaaacaa tgacagcttt tacagaagat
    20041 gaacaagaaa taaatagttg tctagaacgt gggcatgaat tattaaaaga aaaagaagta
    20101 gcagatttgc cattttctct gagtctagat atcttcaatg agcattcgtt tatccaagta
    20161 gcctttgagg cggtgaaaga acgaggaaag acggaagcag caatattaaa cagtggtctg
    20221 tttttaactg aaattccaaa agggcgggtc aatcaggatc agcttcacac tgcgttgccg
    20281 catccgatgc acttgttaaa tgtcacattg ggtggaaatg atctgatccg cttagtttta
    20341 gaaatagaaa aaaatcgtaa ctttttacgt aactatccta tgaagggaat gggatttcgc
    20401 ggtaagattt ttgggcagat ggtctataat ggaatcacat atgattctat taaccatcaa
    20461 gtcttttgga agaacaagcc aatcgatctg aataaaaatt atacttttac taccgtagat
    20521 catttgatgt ttgttccatt ttttccaacg attgagattg ctggaaaaaa tgaatttttg
    20581 ttccctgaat ttatccgaag tgtggtagga gattacttga aagctcacta cccaatcaaa
    20641 taaaaacaag gtataataaa aaagataggt ggtgaacgca tgtctgcaaa acaaaatgaa
    20701 cagcagaacg ttgagcataa aacagaaatt gctaagaaaa aatcatcagc tgaacaggaa
    20761 acaacagtca ccgaagaact gacagctgct ttggaagaaa tcgttgagga gcctaaagca
    20821 gaaaaagtca aaggcgagct agtgacactg ttagatgaca gtaatttttt gataggtgaa
    20881 agacattatc ggcttgtgtc cgattatcgt gaaggattta atgcagaaaa gcttggagaa
    20941 cgttacagtg atgtactagc ccgatatgat tatatcgtag gagattgggg ttatgaacaa
    21001 ctacgcctaa aaggattttt ccaagcggat aatcgacggg cgcatccaga tcagcgaatc
    21061 gattccttgg aagactatct ttacgaatat tgcaattttg gttgtgcgta ttttgtcatc
    21121 gagagaatcg gcggtaaaaa agaaaagaca actcagcgcc gaaaaaagaa aaaaaaccat
    21181 aatcgtgcgt atatcgatga gaaaaaagga ccagtcgcat ctaatcgcaa aaaaccggtt
    21241 attaaaaatc gaaaaacaga gtcagcaaaa acctctgaaa aagtaaaaaa acaagaacaa
    21301 cctaaacaag tagaaaaaac aaaaacagca tttacgatca gaaaaaggga agagtagtgg
    21361 atgaatggac tataaaggat atttaattga tttagacgga acgatttatc gtgggacaca
    21421 acccataccg gccggtaaac gatttgtgga agaattgcaa aaaagaaaat tacctttctt
    21481 gtttgttacc aataacacga ctaagtcacc agaaacagta gctaatcgtc tagcagatga
    21541 gtttgacatt catgtagctc cagagacagt ctacacagct actttggcaa caatcgattt
    21601 tatgaaagca gatggaaaag ggaaaaaagt ctatgttatc ggagaagcag gattgattga
    21661 cttgatttta gctgccggat ttacatggga agaagaggct cctgactatg tagtggtagg
    21721 cttagataat tatctgacct atgaaaaagt agttaaagca acacttgcta ttcaaaaagg
    21781 tgctactttc attggaacga acccagataa gaatatacct actgaacgcg gccttcttcc
    21841 tggagcaggg tcagtcatct cttttgtaga gacagcaacc caaacgccgc cgatctacat
    21901 cggaaaacca gaagccatca ttatggataa agccgttgaa gtattagggc tgcaaaaaga
    21961 agaagtaatc atggttggag ataactatga aacagatatc caagctggga tacgcaataa
    22021 tatagatact ttgctcgttt tatcaggttt tacaaaagaa gaagatgtac ctgggttgcc
    22081 tatcccagct acctatgtga aacaatcact ggatgaatgg agcttctaat atgaaaaatt
    22141 cgagatggca gtggatggaa tatgctggat tgttcagcct atttctgaca ctgatcagtc
    22201 tggcagttgg tgtgacgatc aactttcgac cactatacgt atttgatatc ggacatttgc
    22261 aaattttgga ttatacttct ttagatcaag agacgttact gaaaaatttt gatcacctaa
    22321 tgaattatct caataatccc ttcaaaacca tcctcagctt gccagatttc ccagtttctg
    22381 ctagcggagc ccatcacttt tatgaagtga aaattttgtt tttagtggat tatgctgtgt
    22441 ttttcatcac tttgatcccg agtattttgt ttatcaaata tttgcaaaag aatgatcggc
    22501 tttggcggtt gattcgtccg tttcaaatcg gcatgttact gccagttgtt ttcggttttt
    22561 tcatgatgat aggatttgat cgctttttta tcctttttca tgaaacgttt ttcaacaacg
    22621 atgactggtt attcgatccc gttactgatc caatcatcaa tgtacttcca gaagaatttt
    22681 tcatgcatag ctttatctta ttttttgtat tattag
//
LOCUS       DADVXE010000041        22521 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.042, whole genome shotgun sequence.
ACCESSION   DADVXE010000041 DADVXE010000000
VERSION     DADVXE010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22521
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.042"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(85..537)
                     /locus_tag="KB913_001745"
     CDS             complement(85..537)
                     /locus_tag="KB913_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBB6820105.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(550..960)
                     /locus_tag="KB913_001746"
     CDS             complement(550..960)
                     /locus_tag="KB913_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6820106.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1235..1447
                     /locus_tag="KB913_001747"
     CDS             1235..1447
                     /locus_tag="KB913_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6820107.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1450..1662
                     /locus_tag="KB913_001748"
     CDS             1450..1662
                     /locus_tag="KB913_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820108.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            1802..1957
                     /locus_tag="KB913_001749"
     CDS             1802..1957
                     /locus_tag="KB913_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820109.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(1954..2178)
                     /locus_tag="KB913_001750"
     CDS             complement(1954..2178)
                     /locus_tag="KB913_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBB6820110.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2256..2444
                     /locus_tag="KB913_001751"
     CDS             2256..2444
                     /locus_tag="KB913_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820111.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2770..3105
                     /locus_tag="KB913_001752"
     CDS             2770..3105
                     /locus_tag="KB913_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820112.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3338..4279
                     /locus_tag="KB913_001753"
     CDS             3338..4279
                     /locus_tag="KB913_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBB6820113.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4281..5171
                     /locus_tag="KB913_001754"
     CDS             4281..5171
                     /locus_tag="KB913_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBB6820114.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5214..6014
                     /locus_tag="KB913_001755"
     CDS             5214..6014
                     /locus_tag="KB913_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBB6820115.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            6029..6880
                     /locus_tag="KB913_001756"
     CDS             6029..6880
                     /locus_tag="KB913_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6820116.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            7081..7542
                     /locus_tag="KB913_001757"
     CDS             7081..7542
                     /locus_tag="KB913_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6820117.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7568..8020
                     /locus_tag="KB913_001758"
     CDS             7568..8020
                     /locus_tag="KB913_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820118.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            8126..8320
                     /locus_tag="KB913_001759"
     CDS             8126..8320
                     /locus_tag="KB913_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820119.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNGFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            8351..8737
                     /locus_tag="KB913_001760"
     CDS             8351..8737
                     /locus_tag="KB913_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820120.1"
                     /translation="MKKLHQLISEKESELQNLEDSLGLGFPIVEQAKMTQISHLRLEL
                     EDLRQIEKSIQLNDNQKIVLEWLKSETILTREAPILSVNAFSDKNLLGKLPDKVRKAY
                     KLLACKQEYEVLSAFAQWGLEQEEAE"
     gene            8734..8937
                     /locus_tag="KB913_001761"
     CDS             8734..8937
                     /locus_tag="KB913_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBB6820121.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASNAIRKFGISILNDDRKWEEMR"
     gene            8934..9230
                     /locus_tag="KB913_001762"
     CDS             8934..9230
                     /locus_tag="KB913_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820122.1"
                     /translation="MKIKDGFYASSHGIGGLMLDMPIKNPKTRQKSKFKIGDMVRCKA
                     EEFIYPFRGYVEHVYNHSAIIHIENTMECDKWLAKSKDNLAVARLVDMELINDK"
     gene            9306..9722
                     /locus_tag="KB913_001763"
     CDS             9306..9722
                     /locus_tag="KB913_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBB6820123.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            9983..10120
                     /locus_tag="KB913_001764"
     CDS             9983..10120
                     /locus_tag="KB913_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820124.1"
                     /translation="MDKEIKVTVKLDLTELKELLNKASDQVEQLQETLDEIANFKIQV
                     S"
     gene            10530..10760
                     /locus_tag="KB913_001765"
     CDS             10530..10760
                     /locus_tag="KB913_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820125.1"
                     /translation="MRNYWYISLTNEYPRTIDDCSVRVVRSVQIKKKYSIVEMTREAT
                     PKEIDKCKLLYCGHGFYDEPNIQNNINKNLRD"
     gene            10919..11752
                     /locus_tag="KB913_001766"
     CDS             10919..11752
                     /locus_tag="KB913_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HBB6820126.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELKSNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPKRNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11745..13160
                     /locus_tag="KB913_001767"
     CDS             11745..13160
                     /locus_tag="KB913_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBB6820127.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPENMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTTVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13172..14701
                     /locus_tag="KB913_001768"
     CDS             13172..14701
                     /locus_tag="KB913_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6820128.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEYMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKDPTAKAEYVTKKLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14619..15671
                     /locus_tag="KB913_001769"
     CDS             14619..15671
                     /locus_tag="KB913_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBB6820129.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15673..15990
                     /locus_tag="KB913_001770"
     CDS             15673..15990
                     /locus_tag="KB913_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820130.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            16117..16740
                     /locus_tag="KB913_001771"
     CDS             16117..16740
                     /locus_tag="KB913_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBB6820131.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            16755..17645
                     /locus_tag="KB913_001772"
     CDS             16755..17645
                     /locus_tag="KB913_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HBB6820132.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17668..17883
                     /locus_tag="KB913_001773"
     CDS             17668..17883
                     /locus_tag="KB913_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820133.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            17895..18236
                     /locus_tag="KB913_001774"
     CDS             17895..18236
                     /locus_tag="KB913_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820134.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18236..18607
                     /locus_tag="KB913_001775"
     CDS             18236..18607
                     /locus_tag="KB913_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820135.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18600..18995
                     /locus_tag="KB913_001776"
     CDS             18600..18995
                     /locus_tag="KB913_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBB6820136.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            18997..19374
                     /locus_tag="KB913_001777"
     CDS             18997..19374
                     /locus_tag="KB913_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820137.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19375..19983
                     /locus_tag="KB913_001778"
     CDS             19375..19983
                     /locus_tag="KB913_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6820138.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            19983..20324
                     /locus_tag="KB913_001779"
     CDS             19983..20324
                     /locus_tag="KB913_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820139.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGPVVEEAAEVMEG
                     MQNAVDGKSVSEALSRAYSFIADILFEGQFTGEDYRQGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            20566..>22521
                     /locus_tag="KB913_001780"
     CDS             20566..>22521
                     /locus_tag="KB913_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBB6820140.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKY"
BASE COUNT         8149 a         3281 c         4660 g         6431 t
ORIGIN      
        1 ctcctcattt ctttgatata attattgtag agtttactca gaaatgagga aagagtccat
       61 gtgaaagcat gggctttttt atttttaatg ttgtaatact aaatgttcaa gattatgagg
      121 aagccctaaa tattcaataa tttggaactg actcatatca gataaatctt gttcatctat
      181 tgttctagtt aacatttcaa ttgcaaacat attagcttca gcttctatac cataaatcat
      241 acaactaagg ttgtttgctc taaaagctgc tgtgcaaata cctttatgga gtctaacgtg
      301 ggctatttca tgccataata caaatctttt catagaaggt gataggtttt gattaattaa
      361 tatcacataa catcttttat tgtgtatcgt ttgtcctaat gttttattcc ctaaatcagt
      421 ttcaattaaa tctatatcag aatatttgat tattttatat ggattaatcg catcagatcc
      481 aaactctaca aataattttt ctatttcttc taatatccag tatttgttta aatgcatacc
      541 aaagcccacc tattgacgat attttttagg agtgaatttt ttctttgctt taactttggt
      601 taaggcaagt gcaagttgaa tggcatcgta taatttttcc ttatcttcat cgtctaaagg
      661 ttcaccataa taatttgttt cagcatctga attcaagcct tcaagtaatt tttcagcttg
      721 taaagcaata tcttgtttat ctttttctgt taaatcataa taatggcgtt tatcagtacg
      781 tcctaaaaga taatcagttg atacattaaa gtaatctgca actttttgta ttttatctcc
      841 agatggagta cttttattcc atctagacat gcttccattt ccgaaattta actttctttc
      901 aagttctgcc aacgtcattg aacgttcttt taataagatt tttatacggt ctaatagcat
      961 aggatatgca ttcctttcaa aataccgaca aaaaaagtat ttttctgcaa attatctatt
     1021 tacaaataga gaatttgcag ttatactagt tttgtaagca agatatttac ggcatacaaa
     1081 gactaaaagc aataaactaa tagtctcccc agacatcagt aagctcgctt tttgtgcgct
     1141 gtattttgta tgcttacata atagcatatt tgcagttttt gtcaaactta ttagacaaaa
     1201 atattagaaa atattcgata agggggtatg aagcatgact ttaaaacagc aagtattaat
     1261 tgctttagta aagaaaggtt ggagtcaaag agagttagct cgacgaatgg gtatatcaat
     1321 tacttattta cgagatatct tcatcgaaaa aagaaaacct aaggaacgtt taaaacaaat
     1381 cgaagaactt ttggatatca agttagaagt agattctaat gatcagccat cagaacagga
     1441 ggcgtaaaaa tggtacaacg tttgagcaaa gcggagttta aagagaaata taagtattct
     1501 gaaagtactt atcaaagaag aatgaaggaa tttaaaaaat cacgttttag tgaggggtat
     1561 aacgcagtta cttccaaaga aataacaatt gatgtcgatt tatatgaaca gtttagaaca
     1621 tggcgttcta aaaatcgatt tagagttaga gctgtttgtt aatagctaaa aaatctaaat
     1681 tcaccacttc tgaaaagagg agttgctgct ctcctttcaa gtttgccaaa gtccacgttt
     1741 tttcattttg gcaactcctc ttcttggagg tggtgacggc gagagacgaa ggagggatga
     1801 catgaaggaa gaatcaaaaa tagggatttt gaatgagaac aattacacaa gattaattat
     1861 tgaaacagaa gaagggaaaa aagtagcaga agttacattg accgatgcaa ctcctgctga
     1921 cggttatcgt attcgattaa ctcctaaata tgattaacct tttggtgggt gtggatcgtt
     1981 tccgtgacta tcacggcttt gaatttttcc atctctgcca tgaataaata gctcagatcc
     2041 ttgattttta gaaatctctc tagcgatttt tactgcttct gattttgtat tagtatgtgc
     2101 agtcgcttta gaatttccag cacctttgac attccaacca ccattggaat taggtacaac
     2161 atgttgattt tttcccatag ttttcacctc catttctata gaaatatttt atcaaataga
     2221 aatggagaaa ttcaataaac gaaaggagaa gtgatatggc atataccttg caacaagaac
     2281 atcaaattct cggtttgatt aaacaacgca ggaaacaatt acaagatgac cgtgcagcgc
     2341 ttagaaaagc cgatgagcta tcagataggc aagctgaact aattgcttct gaacttgagg
     2401 atttgagaat gctagaaata aaaaataggg agattagatt atgaagaaga cagacacact
     2461 ttttatagga ttcattttgg ggttattagt gattgtagcg caccaaagta ttatcggggg
     2521 aagcttgttc gcagcattga tggttttaat caatctgctt gattcaaaag aaaggagcaa
     2581 ctatggcacg agaagaagcg ctaaaaatcg gtaaagtgat tgctgataat cggtggggaa
     2641 atagccgccc tattatttta agcaagcaac atatcgaaaa gcaaaaagca tggcaacaaa
     2701 taaaaaagtg actctgccag ccagcaaaga gtcacataca aatttataaa actaggagaa
     2761 ttatatcaca tgaataagaa aattgaaaat cttatcgaag aattgaaacg tgaatgccaa
     2821 aagcaaggtg tttctattat ttgtacagcc caaaaagaag gggaacttaa aagtctcgtt
     2881 tatggtgaga caacagaaat tttactttgt cttgctatgc aagaagaaca tttagatgaa
     2941 aatctcccat tgtcagcaca tattatgcgt agaattgctg tggatgctta cgaacaagcg
     3001 aaaaatgaag aagaaaatca accttcaaat catacttttg ttattaataa caaggaagat
     3061 ttagctgatg tgatgactcg tattctcaag ggggaatttc aatgatgaat gaaaaaacaa
     3121 ttgatctact cattatttta tttttcacgt tagtgattgt agcgaaaagt tatgtaatct
     3181 ttggcttgtt attcgcaatt accatgcttg tgctttgcgt gttagcaagc agaaaagagg
     3241 ttaaacatga acgagttagc aaatcttgac aactatttaa ctgatcctga ttatgctaaa
     3301 ccaccatatg aagcaccaat tgatgaggag gatgaagatg agtaaatcta ccttagaaat
     3361 gagccatcaa gaatggcttg aagaccgtaa gaaaggcatc ggaggttcgg atgttggaac
     3421 aattttagga ttgaataaat ggaaatctcc ttatcaacta tggctagaaa aaacaggaca
     3481 agtagtactt gaagaatcag gaagtgagcc cgcttattgg ggtaatgttt tagaagaagt
     3541 ggttgctaaa gagtttcagg aacgtacagg caaaaaagta cgcagaagaa accaagtatt
     3601 tgaacatcca ttacatccat ttttaagagc aaatattgat cgggaagtag tgggagaaaa
     3661 tgccattctg gaatgcaaaa cagctaatca atttctcggt aaagaatggg aaggcgaaga
     3721 ggtaccgctt agctatctct gtcaagttca acattacatg aacgttctaa acaaagacta
     3781 ttgttacatc gctgtcttaa tcggtggtca aaaatttatc tggaagcgga ttgaacgaga
     3841 tcaagagctg atcgatacaa tcactgaaca attagtagag ttttgggaaa caaacgttct
     3901 tggaggtatc gagccaatta ttgatggtag tcaagcgaca gctgatttct tgaaagagaa
     3961 gtatgcagat gttgaagacg ttcaaacgac gttaccaatt catttcgatg aactagttga
     4021 acagaaaaac gaactcaaac ggactaagaa agaaattgaa tcagctatcc gtcaagtaga
     4081 caacgagatt atcagcgagc taggtaaacg tgaagccagt atcggtatca ctcaaaaaaa
     4141 catcatcagt tggaaatttg tccgtacgag acgtatgaac tcgaagaaac tagcagagaa
     4201 atatccagat gtcgcaaatg atgaagagat ttataacgtt actgaatcaa gaaggctaac
     4261 cgaaagggag atcaaataat atggcaacaa atgaatcgtt aaaaaatcaa ttggcagcaa
     4321 agccacagaa acaagttgca ccaggtcaat taggacttaa agctttgatg aatacaccaa
     4381 caatgagaaa gaagttcgaa gaggtgcttc atgacaatgc taatgctttt atgtcgaatg
     4441 ttatgactct tgtatctaat gacagttatc ttgcagatag tgaaccgatg tctatcatga
     4501 gtggtgcgtt aactgctgca acattaaatc ttgggctaga taagaattta ggttatgcat
     4561 atttagttcc attcaatagt aaaaacaagc aaacaggaaa atgggaaaag aaagctcaat
     4621 tcatgcttgg ctataaagga tatatccaat tagcccaacg atcaggtaaa tacaaagcat
     4681 taaatgtgat cgaagtttac gaaggagaac taaaaagctg gaaccgactg acagaagagt
     4741 ttgagtttga tccaaatggt agaacgtctg atgaagtcat tggatatgtt ggctatttcg
     4801 agttactgaa tggattcaaa aaaactgtct attggaccaa acaagaaatc gaagctcatc
     4861 ggattgctaa caataaagat cgcgataaga caaagttaag tggtgtgtgg gcatctgatt
     4921 acaatgcaat ggcacgaaaa actgttttga gaaatcttct ttctaaatgg ggaatcttgt
     4981 ccatcgaaat gcaagaagcc accacatcgg atgagagagt ccaaagggtt caagaagacg
     5041 gcagcattat tgctgaaaca gaagttgaag aagatattcc tgaaagaaaa gaagcagagg
     5101 ttatatctga agaaaatgaa gatgtacaaa ctggattatt tgatgcatct aatccgccgt
     5161 taaacaaata atgagggagc tttctccctt gcttttctag aggagaaata cgaatgaaca
     5221 caggatatgt caaattacat cgaaaagtga tgaattcatt cgtttggacc aatccttata
     5281 tgtataaatt atggaacttg tgtttgatga aagcgagtca tgagaatcgc aagatacttt
     5341 ttaatggaaa agagatacaa gtgaacagcg gagaattcgt cacagggcgc gatgctatca
     5401 catctgagat gaacgaaggc gtgaaacgtg aacatcaagt gaacagcggt tctgtatgga
     5461 gatggctaaa acaatttgaa aaaaacggaa tgttgaacat caaatcaact acgaaataca
     5521 gcgttatatc aataaaaaac tggtctttgt accaaagcag tgaacaacaa atgaacatca
     5581 aacgcacaac aagtgaacaa caagtgcaca caaacaagaa tgaaaagaat tataagaatg
     5641 aaaagaataa taaaacatca tcgtcgcaac cacgcaaaaa gcgtgtttac gacaccgact
     5701 cagtttacta cattctcgcg gaggagttat tcaaacagat ttgtcagaat caggaaatca
     5761 aaaagccgaa tctgcaaagt tgggcagata acattcggaa aatgatcgag atcgacaagc
     5821 ggaccgaaaa ccaggtacgg ggaatgattg aatggagtca gcacaatgtg ttttgggcat
     5881 cgaatatttt atctgctaaa aaattgcgag aaaaatacga cacaatggca gcgcaagcca
     5941 atcgtgatta taaaacaaaa caaactaaaa cgcttgaata cgagaaattt agcacagatg
     6001 agttgcctat ttgagaggag gcgtaggcat ggaaactgtt ggggaaatca tggaaaagct
     6061 gatacagaaa gtgcttgtcc aacgtggcga atgtcctgaa tgcggacagc ctttgtatgg
     6121 atggcgtacg aagaaccctg atggctcaga acgttgtaag ccaacctgta tgcaatgtgg
     6181 gtataaagca ttgcgagttc aggaagactt acaaacagaa cgaatttaca acgagagcct
     6241 gaaagcaaga gcaatcaatt ttttcaaagg tggttctgtt gtgcctaatc aagcgttgtt
     6301 tgattgcaca ttgcagaatt atcaaattgt cgatcaagaa acaagacaag cggttgaagt
     6361 aaccaaacgc tttgttaatt cagtcttgtt aggaaatcca agtcaccttg ttttaactgg
     6421 aaaacaagga acaggtaaaa gtcacctagc gatggcagcg gcttgggaag tcttgaagcg
     6481 atcaaactac gataaaaaaa tcttatttat cgggttacag gaaatgctgg atcaaatcaa
     6541 attttcgtac aacaatcctg aactcagaaa aacgattgag ggatcgttga ttgcagatat
     6601 caaaacagcg gatttagtca tcattgatga tatcggttca gaactaggaa aagatgcatc
     6661 agatagtcga gcgtttggca taaacacgct aaattcgttc ttggatgcac gacagaacct
     6721 agcaacgatt atcacaacga acttgcttgg tgaagaactg aaaaaagctt acggtacgag
     6781 aacaatatca agaatgtttg tcaactctga tggatttacg atggtatttt ctcaaacagc
     6841 agacaagcgc ataaaaccag tcaaaggagc gatcgcatga atttgactaa acaagaaaaa
     6901 agaatctgtc gtcagataat gttgcaaatt ataggtgatc gtgacatgga cgaattatct
     6961 caacaagaga gtcgaatggt tcggaagata agtaagctaa ttatttatcg ggatacagaa
     7021 agatttctca ctgttttagg taacgtctac gagaatccag agttattgga ggtagagtaa
     7081 ttgccaaaaa tattagatgc atgttgcggt agtagattgt tctggtttga taagaacaat
     7141 tctgacgtaa catttatgga ttgtcgtcag cagtatgaag aattatcaac aggtcatgtg
     7201 atcaatgttg atccagatgt ggtcgcagac tttcgcgata tgccttttga agatgatgtg
     7261 ttcgatatgg ttgtatttga cccgccacac ttaagacatg tcggcgaaaa ctcatggctt
     7321 gccaaaaaat atggaaaatt agacgaactt tggccagaag acatcaggca aggttttgca
     7381 gagtgtatgc gagttttacg accttcagga acattaattt ttaagtggaa cgaggaacag
     7441 ataccacttt ctgatgtgtt agaggctatt ggagaacagc cattgtttgg taataaacga
     7501 agcaaaacac attggcttgt gtttatgaaa aaattcagct aacggaggaa acaaaggagg
     7561 aaaagtaatg aagattgtat taaataaatg ttttggtggc tttgggttga gccatgaagc
     7621 aaaaatggaa atttttaaaa gaaaaaatat tgaagtattc ccatacatca ataactttag
     7681 ctatgactca gatgatgaat acacgagata cacaggccaa aagctaggtt cgatggattt
     7741 tatctactat ttcaaaaaag acccgaaaat cgacaaagtt acaggaattt atagcgaaat
     7801 tgaccgactg tacggaattg ctgatgattc cagtttttca agtgattcaa acagaggtga
     7861 taaggacctc gttgctgttg tcgaaaaact aggaagtgag gccagtggac catatgcaag
     7921 tcttaaagtc gttgatatac ccgatggggc tgagtgggaa ataagtgatt atgacggcgt
     7981 tgaaactgca cattatggtt ttcaaacagg tagtatttag tccactaatg acaactaaag
     8041 aggaggcaga aggatgagtg aagatgaata ctttgaacag tagtctatta acgacagaga
     8101 tttttaactg gaaaggggtg tagtcatgga cgcatcggaa gtagtaaata aaattaatag
     8161 tctcaaagag gttttcggag acgtcgaagt agtgataaac gcacaaggct atgacaacgg
     8221 attttttaag cagattaccg acattagcat tcagcaagga atggaagacg aagatggaaa
     8281 ctttatcgat gaagtagcca ttttagtgac ttgcgagtaa gtaattgaca gctaaagagg
     8341 aggcagaagg atgaaaaaat tgcaccaact catatctgag aaagaaagcg aactccaaaa
     8401 tttagaagat agtttgggat tggggtttcc aattgttgag caagctaaaa tgactcaaat
     8461 cagtcatcta cgacttgaat tggaagattt aagacaaata gaaaaatcaa ttcaactcaa
     8521 cgacaaccag aaaatcgtgt tggagtggtt gaaaagcgag acaattttaa ctagagaagc
     8581 accaatatta tctgttaatg ctttttctga taaaaattta ctaggaaaat tacctgataa
     8641 agtacgcaaa gcttataaac tattggcttg taaacaagaa tatgaagtcc tatcagcatt
     8701 cgctcaatgg ggattagaac aggaggaagc ggaatgaaca acagacatcg cagaataaca
     8761 aaactaagaa aacaggaact gaatgtacta aagacaaagt ttgaaaaaga atatggaatt
     8821 tcagcagaag aaacatataa agtggcaagt cagtttgttg ctgatgcgag taatgctatt
     8881 cgtaagtttg ggatttcgat attaaatgat gatcgtaaat gggaggaaat gagatgaaaa
     8941 taaaagacgg attttacgct agtagtcatg gtatcggcgg tttaatgcta gacatgccga
     9001 taaagaaccc taaaacacgt cagaaatcaa aattcaaaat cggtgacatg gtccgatgta
     9061 aagcagaaga gttcatctat ccgtttcgtg gatatgtaga gcatgtctat aatcattcag
     9121 caatcattca cattgaaaac acgatggaat gcgataagtg gttagcgaaa agcaaagata
     9181 atttagcagt ggctcgtttg gtggatatgg aactaatcaa tgacaaataa aaaagccgga
     9241 tcgctccgac tgattcaata aatccaacac atttattata tcacataaag gagcggtttg
     9301 acttgatgca attgttacga gaggtagatt tcaaacagac aagatgtaat gcgagagatg
     9361 tgctgaagaa ctttcggcgt ttggagcgga tggcaggtcg ctctttgata gatattaagt
     9421 cgccgattat tacggatatg ccgaaggcac cgaagcacgg caataaggca gaagacgcga
     9481 tcattcagat gatggatata gaagcggaga gagacgcaat actagcggct ttgatggctc
     9541 ttagtctgat tagccgtcag atactctact acagcttctg tgacgtaaac aagcactcta
     9601 attatgaaat agggcaattg atacgaggat acggagagaa gaatgtagag aagttgaaat
     9661 ccatcgcatt aatcgaattt gcagaagcat acaaaaaagg cgtgttagtt cagtatcgtt
     9721 gattttgtag ggtttttgta gggatagtgt agggtttttg agcggtttaa cgtgatatta
     9781 tggtagtgtc gaaagattag tgataggtct gagacaaaat aaaatgtaag ggaggaaatc
     9841 tccctcatcg ttttaactta agcttcgata gacagcaacg gaaatattaa gaataaggat
     9901 gtgaatttca actccttcta aattgttctt attatctatc atccgttgtt gtctattaat
     9961 ttatgcatcg gaggaaaaac gaatggataa agaaatcaaa gtaactgtca aattagattt
    10021 gactgaacta aaagaactgc tcaacaaggc tagtgaccaa gtcgaacagt tacaagaaac
    10081 tttagatgaa attgctaatt ttaaaatcca agtttcttag cagtatattt tttagcagct
    10141 gcactcataa aatcatacca agtatcagaa aaatataact taactaaata attaaaaaag
    10201 gtgggtaaat agaaatgacg gcgttaataa tttcaatttt tgcgctctgt cttaatgtct
    10261 atatgattgg atttaaaaat ggacaaaata aaaaatagta gcagccgaga ataattttat
    10321 agtgtcactg tggcggaaat agaagacgca aaggtggagg taggaagcgt atggcgcact
    10381 atcgggacct tgtacaaaac tagaaaggac tagtacgtgt gtggtgcgag ccctagggag
    10441 gaacaggata accgcctgtg tgtaggttgc tattacatat tagatcactc tttgagtggt
    10501 ctttttattt acataaagga ggctacataa tgagaaacta ctggtatata tcgctaacta
    10561 atgaatatcc tcgaaccatt gatgattgtt cagtgcgtgt tgtgcgttct gtccaaatca
    10621 aaaagaagta ctccattgtt gaaatgacca gagaagctac gccaaaagag attgataaat
    10681 gcaaacttct ttattgcggt catggtttct atgatgaacc aaacattcaa aataatatta
    10741 acaagaattt gagggattag aatgcaagaa atggcttaaa aatctccaat caggacaaat
    10801 caagttagac aaagtttccg atttaaagat attgattgaa gctgatttaa tgctaaaaga
    10861 tattgaaaat tagaaaacaa aactcaacct aagaagattg cgaggtggtg tgtattgaat
    10921 ggcaagacaa cgtgatccaa gacgtgatga agccaaaaga atttggttag aatccaacgg
    10981 agaaaagcag ttaaaggaaa ttgcatctga attaaatgtt tcagattctc aggttagaaa
    11041 atggaaatcg caagacaaat ggagcgctga attgaaaagt aacgttacca atggcaaaag
    11101 taacgttact aatcaaggtg gcgctcctat tggtaatcaa aatgctaaag gtaacaaagg
    11161 aaacagcaga gcatcaccgc caaagagaaa taagaatgct cttaaaactg gtgagtatga
    11221 aacaatattt tttgacacgt taaccgataa tgagaaggac atctattcta gtttgaatga
    11281 tgatccttct tttgctttgt ccgaagaaat acgacttctt aaaataagac aacttcgaat
    11341 gatgaaaaga atccaacaag ctgaagctgg actaaatgat gaagaagtcg aacgattgca
    11401 gcagctaaga aagattaaaa ctccgattga aaaaaatggt aaaaagctag aaatcaagcg
    11461 tgaggttatg caagatgtgc agattagcag aaaaaaacat cgcaaaattg atgatattct
    11521 ttcaattgaa gattcattga ctcggattag caaccagtta gctaaagcca tcaagcaaat
    11581 gaatgaactt tatatgaatg aatacagaac tgatttaatt aaagctcaga ctgataagat
    11641 ccaagctgag acaaatgaaa ttggcggaaa taattcaggt gaagaaatag aagaatggaa
    11701 acaggcagtt ttaaatgccg caaacaaacg ggcggtgaaa gaaaatgaat aatgaattta
    11761 ttccttttgc tgatattggt tctgccattg attattacta tgataaacca gtagcttttt
    11821 gccaagatat tttgcatttg aatcctgatg aatggcaaga aaatgtttta aatgatttag
    11881 ctgaattttc aaaggtttct gttcgttctg gtcaaggagt tggaaaaaca gcattagaag
    11941 caggagcaat actttggttc ttaacgtgtc gaccctacgc taaagtaata gcaacagctc
    12001 cgacaatgaa gcaactttac gatgtacttt gggcagaggt agctaaatgg ttaaatgata
    12061 gcttgatcaa aaacttactg aagtggacaa agaccaaaat ttatatggtt ggtgattcag
    12121 agcgttggtt tgctacggct agaacagcga ctaaaccaga aaatatgcaa ggttttcacg
    12181 aggaccatat gttgattgtg gtagatgaag cttctggtgt gtctgatcca attatggaag
    12241 ctattcttgg tacgctatca ggttttgata ataagctgtt gatgtgtgga aaccctaata
    12301 atattgaagg tgtcttttac gattcccaca attcagaccg tgataaatac agagttcata
    12361 aagtatcaag ctatgatagt aaacgtacaa acaaagacaa tatagaaatg attcttaaaa
    12421 aatatggaaa agaaagtgat gttgctcgtg tccgtatttt tggagaattt cccaaaggtg
    12481 cgttggattc atttatcagt cttgaaacgg ttgaattggc tacagaaaaa caaattagtg
    12541 attctttagt caataaaaca acggttgctc atattggtgt tgacgtagct cgatatggtg
    12601 atgattctac gattctcttt cctagaattg ctaccagggc attggagtat gagaagtatt
    12661 caaaacgtag cactatggaa acaacaggat atgtcatcaa catggccaag aatctaatga
    12721 gtcaatatcc gagtattgat aaagtgatga ttaaagtcga tgacactggt gtcggaggtg
    12781 gtgtaaccga ccgcctagaa gaacttatag aagacaagca ttatcctttt gaggtgtttg
    12841 gagtgaataa cggttcaaca tcagaagacg atttttacga taatttaggt actcaactat
    12901 ggggaaacat caaggaaatg ttagaagaaa atatgacagc aaatcttaac ggagaacagc
    12961 ctgttattga attgccttct gatagttcgt taatcaaaga attaagtact cgcaaattca
    13021 aaatgacaag tagaagtcgt atacgtttag aaagtaaaga tgatatgaaa aagcgaaata
    13081 ttggtagtcc cgatattgct gacgcactgg ctttagcgtt ttatgagcca ccaagtcact
    13141 atcaatttat tcaattttag gaggtgagtt tttgattagt acagtattat ctttagagag
    13201 atataagaag ctacgtgtta aatatgcaac acaaattgaa gatggaatgt ttgatccgaa
    13261 tggttttata gaatatatga aaccattttt tgctgatcgc gaaagaaaat atctagctta
    13321 tactagcgaa aagaatgaaa tagacaatag accaaagcct aacactgata ttgtaaaagt
    13381 taataataaa cttcatgctg gtatgtattc aattgtcgta gaccaagcag tcaatcattt
    13441 tactggtata cctatcaaat gggattacga tgtatcggaa caaaaaagaa cactcattca
    13501 aagattaaaa gataaattct taaaaaatga tatagaactt ccaacagttc cagaagcttt
    13561 taacaaatta acaagcaatc ttgattccat gagattcgca atgcttgatt ctgaaactgc
    13621 aacttttcaa ggagcttgtg gagtagcttt ccgattgtta gagcctgtgg aagaagatga
    13681 tggttggaag ttaagagcaa gtaatattga accttggaga gcagaaagat atggaaatgc
    13741 cggaatctat atcaaagaaa agtatgactc ttaccagaaa aaattttttc aagaaatgaa
    13801 agttatgaca agaaataaaa ttctgacata tgcttgctat ggtgatttga attttgttac
    13861 aagcggaacg ttcaaaaaaa ttgatgagac cgataaccct ttggggacga ttaccttggc
    13921 agaatttaaa aataatacga atcgttattg tgattttgaa gtagctgagg aaattggaga
    13981 tgcaattgat cgtgctttgt ctgatcaaca aaacgaaatc gaacaattta agcttgcgta
    14041 catgcttgtt actggcacaa caatgagcaa aggcactgct aaagaaatga tgaatcagct
    14101 agggattatc aacttaaaag accctactgc aaaagctgaa tatgtcacaa aaaaattagc
    14161 aaaagatttc aatgaatatc atatggatct attgaaaaaa cagttttaca ccatttgtaa
    14221 agcaatcgat tttaacgatg aggtgtttaa atcaaacagt tctggagaag ctcgcaagtg
    14281 gcaaatcatt agcctagaag cgaaaacaaa tactaaagag caatatttta gagaaggatt
    14341 gaaagaatgc gcagaaacaa ttgctgcttt tcttaagttt catgacaaag tagaaattga
    14401 gcctgaaaaa attattttta ctttctctag atctttgcca actgatttaa gttatttagc
    14461 tgaagcttta cctaaacttg caccatacgt atccaaacga actattcaga gccaaattcc
    14521 atttgtaaca gatgttgatt atgaaaatga aatgatggaa ttggaaagtg gaagtgctta
    14581 tccagatagt gaatacaatt ttggcggagg tggcaatagt gacgatagaa acgaagtatt
    14641 ggaccaaacg tcgagaactg gaggatcaag caaggctcaa acaagaaaat cagacactta
    14701 aaaaattaac tagtgtattt cctgaagcac tgaaagagat acaagcaaaa ctattatcac
    14761 aagctgactt acacaatatc acttatccag aaatgatgga gttttacagt acaagtaatc
    14821 agaaaaaata tcgtgaatat gtggaaaaaa attataagtc attaaaaatg tatgatgcaa
    14881 aatacaaaga gtttatcgat gaattttttc caccatttga ctatgcaaaa gtcaatcgct
    14941 tattacaaat acgatcagat gtatttaaaa ttcttgcaga atatgcgatg gatgcagatg
    15001 tgaatcaata tttttctgat cgcttagagg aaattcttca aagaacatat tcttctaatg
    15061 ctaatgtttt tgttcaactt ttaaacgttg atataccaaa ttatttacca gaaaatgaaa
    15121 ttaaacatta tttgaactat ccatggtcag gaaagacatt ttcaagaaga ctttggggaa
    15181 atatttcatc gcttgaacag aaactctcta atgctattgt aaaaagtgtt gctagtggag
    15241 aaggcgttat acacgcatta aacaccatga gattagactc agaaatttgt gacatgttta
    15301 agttagaaga atcaaagtat aacaaagcga tagaaaatct cgttcgaacg gagtatgcaa
    15361 aatttgcaca agatggtatt gaaaaatcat atttagaaac aggtattgag gaatacaacg
    15421 tattgactgc aaaagatgag agagtttgcc ggatttgtgg aggaaaggca agtaagaatc
    15481 cctataaact gaaagatgct gtcataggtg aaaatcgagc acctttccat agtcgttgta
    15541 gatgtacgga tgttcctaat ttaccaaaat taggaaagga tattgatgaa gaatatgacc
    15601 gtttatttgg cgatttatta gatgagtttg cacatgattc ttttggaatt aatttgaaac
    15661 ggaggaagta gaatgaaaga tttttttgaa gcagtactaa caattaatgt aaatgctgat
    15721 attgcagaag cctacaaaac agctattgag tctgagaacc atcctaatgg cttgagagac
    15781 cattggaatg gcaattatgc ctacgtggtt attggcgatc aaactgttaa ttatcaagat
    15841 aatactccag ttgataagaa taccgttaat ttaacgattc aattattatc tcattcatta
    15901 ccaaatttaa aagaaacagt tgattggtat gaaaagatgg gatgtattgt tgttagaact
    15961 gactacaaag aaggaaagtc tagtaattag gcttttttat tttgtccgaa atgacgttaa
    16021 actagcgcaa tactgggctt ggttgaatgg tggggcgcaa ctattaaaac tcaaagcaat
    16081 gcggggcgtg aaaacgaatc gtggggcgaa aggagaatga gcatgaaaca caaatcatta
    16141 atgccaatga atttgcaata ctttgccgaa ggtgacgatc aaaagttttc ttttgatgac
    16201 ttcaaatctt ttgtggaatc caatgaagaa gctcaaaaat ttattcagtc acaatctcaa
    16261 agtgttgccg acaaacaatt ggaagcttgg aaacaaaata acttagataa aattaaacag
    16321 gataccatca aggaatatga ggaatctaag aaaaacaagt cacctgagca aattcaactg
    16381 gaaaaactac aagctgaatt tgaagcagaa aaagcgttgc gtgtgacaag tgataataaa
    16441 gcatttgttg cagaacaaat tgctggatta gaactagatg gagagttaaa agagtctatt
    16501 tctcaattta tgctaaataa tcttgttagt tcggatacag atttcactaa gaatgctgtt
    16561 gaaggtttta caagtgtttt gaatgcaatt aatgagaaac atgcagatgc attaaaagaa
    16621 ctacaaatga agtctgcatt tggtggaact caacaatcga ataaccaggt tcagcagaac
    16681 aatgaaacat taacaaatcc agaagaacaa ttaggacaaa ttcttcaaca atttaactag
    16741 gagagtgaaa aattatgaaa aaaacatctt taaataattt agagtatttg gatatttcac
    16801 cagcgattaa tgctatgcaa gtaccaaata cacctttttt aagctattta cttggtgctg
    16861 gaaaaacaga gccagcaaac tcgacagaaa ttaaatggcg tgaatatgat atcaacaacg
    16921 atgattcttc tgaaaaactt gagggcggag aatatccaga tgctgaatca ggtcgaactt
    16981 ggtttaacaa ctatactgaa atttttagaa aatcaacctc tgtatctggt acattagatg
    17041 ctattaatgt gaatggagtc ggaaatgaat taactaatca agtagcacta cgtggtatgg
    17101 aaatgaaaat tgatttgaac cgaaaattga ttactggtgt aaaagctgat gaaaatggtt
    17161 ctaaaggtcg tcgaatgaat gggattttga acttgatcaa ttcagcaaat aaggcagaaa
    17221 cagccactgc gggtgcagta acaagaaaag atatcgatac tttatttaaa ttgatgtatg
    17281 aaaaaggtta tatgggagaa aaactatgct tgatttctcc agatatgcag gagttaatga
    17341 ctgatgagtt agatggaaaa tcaacaaaaa ttgttcagtt cggggaaaga gtaacttttg
    17401 gattgcaaat tggaaatatc gtgtctaatt acggtacagg tattgctcta ctagaaccat
    17461 cattgccaaa aggaacaatt gccgcaatcg atactaatta tgtgaaacta cgtccattac
    17521 gtgaatggag agcagaagaa cttgcaaaaa caacggattc tagacgtatc ggtcttgtag
    17581 gtgaatactc tcttgaatac aatgcttcaa actctggggc aattttaaat ttaaagtctg
    17641 aataaaaggg agttagtact cccttttttg ataggaggaa ttacagtggt aaaaaaagat
    17701 gaaactaaaa aagatgaagt cgtgaaatat agagtaggta aaactaaaaa ttttgttggg
    17761 tttgttcatc ctaaaactcg tagatttatc acagcagatt caaataacga atttatcatt
    17821 tctatagatg ataaagaagc aattgcaatt ttggaagatg caattgatgt taatgaaatt
    17881 taggaagtga tctgatggat gaatcgctaa aaacggaaat cattgagtct acaaaagaag
    17941 attttccaga tttgagtgaa gaacgcataa ctaatttatt agaaataatt ttgctagaaa
    18001 ttgaatcata caacacttgt aaaaatgata tttcatggga aaagttaaaa agcgtgatta
    18061 gtgaagtgtt gtataaaata ataaaaaatg aatcagaaaa aacagtatct tcagttagac
    18121 gtggcgatac aacgattagt tatgcttcaa caacaaatga tgttagtgag ttacttctag
    18181 gctatggtga tttgatacga agagttattg gttgtggagg attggagttt ttttaatgaa
    18241 tgaagcagat attttagaaa ctacttatga agatagttgt attattgaaa gactgacgga
    18301 cattgaagat tctaatacaa atattactat tcaagattac aaaaaagtat atgataatcc
    18361 tatttcttgc gctctttcac aaggtcaaat cgatggacta gcagtcatag aagatggaga
    18421 gatggtaaat gtttcaactg acacatataa attatttgtt catcctaaga ttaaactaaa
    18481 aaaaggagat cgaataacaa taactcaaaa ggccagtggc ttaatttttt ctctatttgc
    18541 tactaagcct ttttactatc ctagtcattg tgaagtgaat ttgataggaa gtgagaaaaa
    18601 tgggtaatct caaatatgaa tcaaatgcag aaaagatcat tgagaatttt aaaaatatga
    18661 ctgtaattgc tcaaaaagaa ggaatatcct tcgttaacga ttcaatgaat aaagtcgtta
    18721 gtttagctaa accattaact cctgtaaaat caggtaattt aaggcgagga tatcgtgtag
    18781 taaaagctag aaaactatca agcggtcgaa ttgttggagc agttataaac aatgaacatt
    18841 attttaaata tgtagaagaa ggtcatagga ctaaaaatgg tggctttgtc aaagggaaat
    18901 tcatgttaac tcgtgcaacg aatcttgcaa atatgtctta tattcctcga agatttaaac
    18961 aaatggcaat aaaaatcgtt aagaaaggaa agtaacatga aagatgaaat cattgctgca
    19021 atcagtagca aattaaaaga aatctatcct gatgggacaa tatatcttga ttcagttatg
    19081 cagtcaacta aagattttta tttcgtttta tcagtaatgg aatctggaac tgaaaatgta
    19141 ggaattgata ttcaaaatgt ttctttctta attgatattg cattgattga taataaacct
    19201 aatagaaatt taattaatga attagtctca cgttgtggga ctttttttaa tacgattaca
    19261 atcgatgagc aaatattatt tccaaaagcc tatttacctg atgaagcaga tggtgttcaa
    19321 catattcgtt ttacattaga atttccacaa tatattgaat ggagtgaaag ataaatggga
    19381 gaaaaaagaa gtaaaaccgg aattatttct gtcgaaaaac ctacttggtt tcctttggaa
    19441 gatgagacag ggaattttcc ggtatatggt actgcgttgc caatgggaac agcagtaagt
    19501 atcaaaccaa cagctaatta tgaaacaaca caagattatg gggattcagt ggttcaagat
    19561 caatttacag cttttggtgg tgcagaagtt gaactggaag caaatggata tactcataaa
    19621 gttttatcta caattactgg agggaaaatt gttaaaggtg gtgccttgcg ttctggagaa
    19681 gatattgcgc aagatggtgc gtttgcatat agacgtaaaa aatcgaatgg gaaataccgt
    19741 tatacggtct tttataaagg acagtttgct ctagattcag atgaaacatc aacgattgaa
    19801 ggaagtaaag taagttttac tcatccaact tggaagggtt catttgtaga tgtaccagga
    19861 cttggatata tgtattcagt tgatgaagat gatgaaggcg tggataaagc aatgatcgga
    19921 aattggttta caaaagtagc aattccaatt gaagaagcag aactttcagg aggtacagaa
    19981 taatgtcaaa atatcaaaca acgattaaat taacgaaaaa agatgaagaa ggtaaatatg
    20041 agcaagtaca atttaaatct gctgaatttc taccaggccc agtcgtagaa gaagcagcag
    20101 aagtaatgga gggaatgcaa aatgctgtag atggaaaatc agtatcagaa gcattaagtc
    20161 gagcttattc atttattgca gatattttgt ttgaaggaca gtttactggt gaagattatc
    20221 gtcaagggat cgatgctcga gaaattgctt cgttgacagg taagttatta aaatctgtta
    20281 ctgcaggctt tgatgaaact tatacagaaa cgaaaaaaaa gtaagcgaag ctctcaaata
    20341 tccttttttt aaacattcga ttacttatcg agaattagat ttaaagacgc aattactcga
    20401 agcaggttgg acgttaccag aaattgaacg tactgacttt gacgagttaa tgcgtctttt
    20461 tgcttttcga gatgcagtaa aagagcatga ggatgttgag tactacgata acttcaccca
    20521 attttaggag gtgatacttt gaataacgat gacctaattc tgaagatgat actagatgaa
    20581 tctggtttta ctgccggtat gaataatgct gtcaaaaagt tgaactcttt tgatgaaaca
    20641 atcgaaagaa aaagtagaaa tagtggcagt tcattaggta gtatttggaa aatatttgct
    20701 ggaagttttc tagctagcgg agtaactaga atcgtaggag ctggctttga tctaatcaag
    20761 ggttccataa gtggagcggt tgatcgagta gatacgatga ataacgctct acgaaatttc
    20821 caaaatatgg gatttagtaa ttcagaaatt atgaagaata tcggaaagaa tgggctttta
    20881 tctcaaggta ttcaaggact tcctactgct ttgaatgatg cgataagtca tgttcaactt
    20941 cttgcttctt ctacaggtga tttaactcgt tcaactcaaa tatttaaagc tttaaatgat
    21001 ggaattcttg gtttcggtgg ttcaactgat caagttaatg aagctgttat tcaattatct
    21061 caaagtttct caaacggaaa agtagacgca caaacttgga actcaatgat caacgctcaa
    21121 cttggaccta ctctttctgc tattgctaaa aagatgggaa ttacaatggg agatctgaaa
    21181 gaaggtttat ctcaaggtaa gatttctgtt gaagaattcc aaaatcaatt aatagaaatg
    21241 gataccaaag gtggcggagg acttaaatca ttaagtcaaa tcgctaaaga ttctactaag
    21301 ggaattaaaa cctctataca aaatgcaaaa acagctgtta cacgtggtgt tggtgaggta
    21361 atagaaggat taaataaagc attagtagat tcagatttag gtggatttaa gggaattatt
    21421 gataaagtgg gcagttcaat ggaatcgttc ttaaaagtaa ttgctgcaaa tattcctaca
    21481 gcagtatcat ttttaagtaa tttatttaac gaaattcaaa aatttggttc tgctttgaaa
    21541 ttcatgatgc cctttcttgt tcctgcagct accgcttttg gagcgttcat gtttcaactt
    21601 aaaggtatac cagcaataat aaaaagcttc aataatttta agaatgccat aattggcgtt
    21661 ggaaattcat taaagattat gggggcaata gctgctgcta attcatttgt tttaattatt
    21721 ggtgcagtcg ttggtgcaat agctgttttc ggttacttta tggcaaccaa tgaagagctt
    21781 agaaacaagg ttatatctat ttggaatgat gtgaaagatt ccgtaattgg tgtattaaaa
    21841 aatataaagg actggggaat tgatacttgg aattctgcta aagaaatggc atcaaatgca
    21901 gttgagggtg tcaaagatgc ttggtcagga acaaaggaat ggttttctaa cacctggaaa
    21961 ggtattaagg atggggccac aggtttattt gataaaacag tagagacttc aagaaatgca
    22021 gtcgatagtg taaaaaatgc atggtctaat atgaagaaat ggttttctga tacttggcaa
    22081 agtataaaag attcagccag agaaaaatgg aatggaatca aaggttctat tatgtcagtt
    22141 gctggtccat tgattacagg tataaagaat gcatttttac atgttacttt ttatctagag
    22201 accttatgga ataatttagt tgagattggt aaaaacgtct ttgagatttt aaaaaatgtt
    22261 atacttgcgc cggttttgtt tattacctcc atgatttctg gtggatggga agaaacaaaa
    22321 aataatatga ttgctgtttg gaataatatt aaagaaagtg ccataaatat ttgggaatct
    22381 ataaagaata tatttgtaag ttattttaca aatatttatt ttgctgcact caatatttgg
    22441 acagggttca agcttacatt gataaatatt tggaatgaag tggtaaatca agctaaatcg
    22501 atttggttaa acataaagta t
//
LOCUS       DADVXE010000042        22324 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.043, whole genome shotgun sequence.
ACCESSION   DADVXE010000042 DADVXE010000000
VERSION     DADVXE010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.043"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            5..403
                     /locus_tag="KB913_001781"
     CDS             5..403
                     /locus_tag="KB913_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBB6820141.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1081
                     /locus_tag="KB913_001782"
                     /pseudo
     CDS             387..1081
                     /locus_tag="KB913_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
     gene            complement(1675..2562)
                     /locus_tag="KB913_001783"
     CDS             complement(1675..2562)
                     /locus_tag="KB913_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBB6820142.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2747..3586
                     /locus_tag="KB913_001784"
     CDS             2747..3586
                     /locus_tag="KB913_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6820143.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3782..4756
                     /gene="sgrA"
                     /locus_tag="KB913_001785"
     CDS             3782..4756
                     /gene="sgrA"
                     /locus_tag="KB913_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBB6820144.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5054..5410
                     /locus_tag="KB913_001786"
     CDS             5054..5410
                     /locus_tag="KB913_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820145.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5413..6570
                     /locus_tag="KB913_001787"
     CDS             5413..6570
                     /locus_tag="KB913_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820146.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6596..7036)
                     /locus_tag="KB913_001788"
     CDS             complement(6596..7036)
                     /locus_tag="KB913_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBB6820147.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7196..7702
                     /locus_tag="KB913_001789"
     CDS             7196..7702
                     /locus_tag="KB913_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6820148.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7870..9783
                     /locus_tag="KB913_001790"
     CDS             7870..9783
                     /locus_tag="KB913_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBB6820149.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9788..10789
                     /locus_tag="KB913_001791"
     CDS             9788..10789
                     /locus_tag="KB913_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6820150.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10991..11197)
                     /locus_tag="KB913_001792"
     CDS             complement(10991..11197)
                     /locus_tag="KB913_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBB6820151.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11843..12691)
                     /locus_tag="KB913_001793"
     CDS             complement(11843..12691)
                     /locus_tag="KB913_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6820152.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12690..13757
                     /gene="gnd"
                     /locus_tag="KB913_001794"
     CDS             12690..13757
                     /gene="gnd"
                     /locus_tag="KB913_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBB6820153.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13759..14760
                     /locus_tag="KB913_001795"
     CDS             13759..14760
                     /locus_tag="KB913_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBB6820154.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14757..15041
                     /locus_tag="KB913_001796"
     CDS             14757..15041
                     /locus_tag="KB913_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBB6820155.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15074..15871
                     /locus_tag="KB913_001797"
     CDS             15074..15871
                     /locus_tag="KB913_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6820156.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15885..16718
                     /locus_tag="KB913_001798"
     CDS             15885..16718
                     /locus_tag="KB913_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6820157.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16736..17593
                     /locus_tag="KB913_001799"
     CDS             16736..17593
                     /locus_tag="KB913_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6820158.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17615..18124
                     /locus_tag="KB913_001800"
     CDS             17615..18124
                     /locus_tag="KB913_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6820159.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18161..18562
                     /locus_tag="KB913_001801"
     CDS             18161..18562
                     /locus_tag="KB913_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820160.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18674..19027
                     /locus_tag="KB913_001802"
     CDS             18674..19027
                     /locus_tag="KB913_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820161.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19061..19504
                     /locus_tag="KB913_001803"
     CDS             19061..19504
                     /locus_tag="KB913_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBB6820162.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19521..20606
                     /gene="uxuA"
                     /locus_tag="KB913_001804"
     CDS             19521..20606
                     /gene="uxuA"
                     /locus_tag="KB913_001804"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6820163.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20599..21312
                     /locus_tag="KB913_001805"
     CDS             20599..21312
                     /locus_tag="KB913_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6820164.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(21519..21668)
                     /locus_tag="KB913_001806"
     CDS             complement(21519..21668)
                     /locus_tag="KB913_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820165.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            22064..22264
                     /locus_tag="KB913_001807"
     CDS             22064..22264
                     /locus_tag="KB913_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6820166.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7689 a         3430 c         4623 g         6582 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcagcgata acgttaggta aagagctact
      961 agatcaagta ttagagatgc cctcgattga taaagcagtg aggggcttcc aagaagattg
     1021 ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa aaggtcgctg attacttctg
     1081 aatcaatttc tccataaaat aaacgatagc cttctcgaaa actcgaggag gctatctgac
     1141 gattcaatat tcattaattt aaagtttggg tgactattac taactattac ttatttctca
     1201 tttaaacgat gtattcccta acctctaata catccttgta actctgaagt tacgccagtt
     1261 ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata aaaatatctt tcgtgtttct
     1321 ctagtataac agaataagaa gaacaagtcc agaagggata tttttagtct tttttaaaat
     1381 aacttttcag tcgagtttga gtttatgata gttgtttttg aagcgatacg gcaagtgaaa
     1441 aaatagggaa gcatgaaaga atctacttaa tggcgcattg attcatgtga tagaaataaa
     1501 aaactttttt aaattatatc ctcatgattg taacaaatcc agtgatttgt tttggtacaa
     1561 ataaaaaaag gccccgatga agttgtggca aaagtggttt gcctcaaaaa taagaaggaa
     1621 tttccaaaaa tcacttctca aattttgcca catccccaat tgggtcaaat ttgtttattt
     1681 gaatatattt tttacataag gatctttaat agttacattg tcttttttca tcactttacg
     1741 gattgtttta tccatgaatt ccgtatcaag agtttttgct tcggtagcaa ttttttctag
     1801 ctcagatttg tatttgtctt tattagaacc tttatcctgt ttttttacca tttttactag
     1861 ataatagctt tgctgataag tcgttggatc tgttacagga atgatatcag aaacttcccc
     1921 gttttttagt ttaaatgctg ctttttttac ttcagtagga atctctggat tggttgaatc
     1981 aaaattcatt tttccatcag tttcctttaa tgttttattt tttccataag cttgaacaag
     2041 cttggagaaa ttttctcctt catttgcttc tttttttgct ttatctgctt cttctttagt
     2101 cgaaaataga atgatctgtg tactaacttc tggatagaat tctttccaag cagtgtctag
     2161 atctttatct gttaatttta cattggcttt caaaccgtat tggaaagcca gcatctgttt
     2221 aaagagtttc ttatatgtct cttctgtttg gccaactgct tttaattgtt ccttgtagtt
     2281 tggaccgagt tttttgattt gttcattata ttcttttgtt acttcctttg aagaaatctc
     2341 ttttccgtat acatcatcaa atgctttgaa gacaatcatt ttttttaata gtgtttgatt
     2401 atttgattta acttttgggt tatcataaaa atcctgaact gtaagtgttc cacctttaaa
     2461 cgttgcaatc gtttcattgg acttgctaca acctgagaat agtaaaattg cacatgctga
     2521 aaggcacata attagtagtt gttttttcaa aaaatttccc atcctttcct tattaaaaac
     2581 agtctaacag aagaattagg gagacagtct ttcattttcg taaggttgct gtagatattc
     2641 ttagttcgta aaaatctatt ctctctatga tggagaacat ttacatagtt ttcacgagac
     2701 aagaaagaaa agggttgtta aacttaatat aaaggaggga tgaaagatga tcaggattat
     2761 tcggttgatt ggatctgttt taatagtctt tgttggtttt gttttaggaa ttcttgtcaa
     2821 taatgcactt gcggatatgt ttattggaaa tagtgaatgg attggagcaa ttgccggtac
     2881 ggtcggacat ttagctgttt ttttactagc tttatttctt gctagtaagg tcgaaggaaa
     2941 aagaatagaa gattatggtg tttctgttcg aggaaaagac tgggggtatt tagcgggagg
     3001 tctcgttgtt ggaattggag tgtttctgct tattactagt ccattatatt tgacgggggc
     3061 gtatcggtta gattcaggaa acgcaaacat tgtgccgctg ataacgagtt ttattttatt
     3121 tattgcagtg ggggcatcag aagagctttt attccgtggc ttttttcagc atcagatgct
     3181 tagatttggt ccgttaatag caatgattgg atctgctgca ttatttgctc ttttgcacgg
     3241 attgaatcct aacatgacat ttctggcagt tttcaatatc tttttagcag gttgcttttt
     3301 cagcgcactt atctacagta caggaagttt atttacggct attggtgctc atattacttg
     3361 gaattggaca caaggagcta ttttgggtat accagtcagc ggaacgcaag aacaaggttt
     3421 tttctccact ctgatccaat cgcaaaatac aataattact gggggaaact ttggggctga
     3481 agcatctata tcaactacat tattcttgtt agtcttgatt gttggtttgt tactctatgc
     3541 atataaaaca aagcggatga agaaatacac tgctgtttat caataaaaga tgaagaaagc
     3601 aaggctgata tcggtcttgc ttttttaagt ctgtcattga ttaaacgaaa aagtaaacaa
     3661 attcaagcga atacacgaca tcttttgtta gattttcaca actgactgtc gtgttctcat
     3721 cattttcatt ttatataatt cctttatcaa atagaaggta attatatgga gagtgataga
     3781 aatgaagaaa acagcgaccg tattatttgt tattcttggg ctgagtataa ttgcagcaat
     3841 gattggaatc agtacttctg caaatgaacg ggcaaatgag aatctttcat ttactgtgaa
     3901 aactgatcgg attgtttatg acatgacaca acaagtcatt actattccag tcaaaccaaa
     3961 caaaagcgtg aatgctagtg atgtacatgc tgttctaaca tatggttggg atggtaatgg
     4021 aagttcagaa aaagttattg gggaagttta tttaaaagac gtacaatgga ccgctggtat
     4081 tgagtataca ataatgattt ctgcagaact atcgattgat gagatcaaga gtaaagataa
     4141 agttgatttg attgtttttt atgatggaca gatgacgatc acggagaatt tgaaaccaag
     4201 cagttggaca gttgttggac cgccaagcag tacggatagc acaagtagtg aaagcagtac
     4261 agaaaacacg agcggtgaaa gcagtacaga gagtacgagc agtgaaatta gcacagaaaa
     4321 cacgagcagc gaaagcagta cggagagtac gagtagtgaa agtagcacag gaagcacgag
     4381 cagcgaaagc agtacggaga gtacgagtag tgaaagtagc acaggaagca tgagtagtga
     4441 gagtagcaca ggaagcacga gcagcgaaag cagcacagga aaagtaaata atgaacttga
     4501 tttggtacct atcataccaa ctaaggaaca aaagagaaat gcagggagca acctaaaaag
     4561 tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat catcaagaaa aagcgaaaga
     4621 aacagataat agaaaaagcg atttaccaga aactggtagt agaaccttga acaagctaat
     4681 tacatggatg ggtgtgttac tcattttgat tgtaggagca agctattttc gttctctctt
     4741 ccatcgagtg aaataaagaa taaaagcaac agatctaaaa ttgaataaaa cgatagattt
     4801 ttgagtgaat atttcattcg agagtgctgt attgcctggc gaagttgtag ctttgccaga
     4861 tctatttttg tttactaaca tatttgagaa acaggaaata acaggaacac aaatggaaaa
     4921 taagagcaag aataattgac aatgcacact gcgcatggta gtatctctga aaaatcagta
     4981 acgaatctat ttgtacgtta ttcatgtagc tgtcggaata agtctaaata atagataaaa
     5041 aggagtatgt actttgtttg aagaatttat tgatatcaat gaaaggcaag tatatcaatt
     5101 tttgaactat tgttatgaaa gagacgagaa attatatgtg gtgaaggata tcgctttaga
     5161 tctaaactac accctggcta agatgaattc ggtgattcaa caagcagaat cgttttgcga
     5221 aaggtatcca gaatataaat tatcttttct ttcagaaaac aagatgataa aagtcgagtt
     5281 ttcttctcag tttttactga gtaaagttta ttctatactt ttagagggaa cgattggtta
     5341 tattttactg gattcacttt acaaaggtac ttatcaatcc ttagaaaatc ttagtcaaaa
     5401 aattatataa gtttgcgtac gattcaaaga aaattaagag aacttaatac tattttgaaa
     5461 aactatcatt tatcttgcag cttgaaaaaa ggtaatccga tagaaggaga agaataccgt
     5521 atccgatact tttttcactt gatgtattgg cagtcattcg acgaaaatca ttctgatata
     5581 ttatcaagta taaaaaataa acgtcaacta ttagaaaaat ttgcgaaaca tgcgccatat
     5641 acgcgtagta tagatagaaa gaaatggatc agcctactaa gaatttcgtt gcaacgaatg
     5701 aaacaaggcc actcgattac gtatgtccca gaagagatga acaaatttgt gcatccattg
     5761 ataacaaaag aagagtttac gcattacata ctagagcctt tttttgaagc aaacttctgg
     5821 tcgatgaatc acatcactcc aacagagcaa gcttaccttt attttatgtt tggtgtaatg
     5881 aacacctatt tggaagaaga tttgttggat actccagata aagtacaaga aagttggggc
     5941 tggattgaat cgtctattgt agaaaatttt gaaaaaaact tcaagatttg ttttacaact
     6001 tcagaaaaaa attatctata tgtcaatttg gcaatgatcc atttgtattc aagggttttt
     6061 gggacaaaaa agaaggtgga tgcttttgga aaatcagcag aagacagaga ttttcagcat
     6121 atatttccag tgatgtatcc aatcatgcaa cagtttttta gtggggtagc tcgcagaatt
     6181 ccagagctta atacttatta tgaaaagaac agacggttga tttttcaata ctgtatgtta
     6241 gtcagggata tttttataaa acacgaacaa cctgtcatat tctatattca atcaaagtat
     6301 ggtaaaacac aggaattatg ggcaaagaaa aggatattat ctatgactga acgcccaata
     6361 aaatatagtg catccgctga tcagttacct gatattgtca ttagcgatta tcctatcgac
     6421 aaaaaggcat atgatcaaac gaatacacag atattttact ggaatggaca acctacaaaa
     6481 aatgattggg cgcgtctgaa agctgaaatc ataaaaatca ggaatgagaa aaatagatcc
     6541 atattggaaa aattggattt cgttaattaa gaaaagcaga ttgtttatgc caaaattaag
     6601 acattgcaaa aagattattt tctttaaaat cgacaagatg accagaaagc aagagttcgt
     6661 tgagctcttg ctttctttta gttttagaaa ggaacatcct gattttatct tcgctaaatc
     6721 cagtcaaaag ttttgcagat tggtcgtaga taatcggttt tttcaataaa gaaggggatg
     6781 tacgaatctc aatatatagt tcactcaaac tgagttcatc tattctgtga acaagatttt
     6841 tataactaat agaatgagta gagagcattt cggtcacgcc gttgtttgtc aattttagta
     6901 agtggataaa ttcatttttg gttagtggtt gacgaattaa gttctgttcg ataaacggta
     6961 tatcatggac gataagccaa cgttttgcgc gtcttgaaga cgagcagcca gaacctgtat
     7021 acaatttaat catcatacat tcctccaata gctaagtatt tatgaaataa taacatgaag
     7081 aaatagtcga aaagtgccat ttagaggtgt aaaataagaa aatgttgtca cgtataatgg
     7141 aactagctag ataagaaata ctattaaatc aagaaaaaag aaagaaggca caagtatgtc
     7201 aaacacagcc gacgcaatag tagtgatcga tttacaaaaa ggggtatgtt ttgattcttc
     7261 gccgatacac gaattagaaa cagtgacagc attagtgaat aaaagaatca aaacatacga
     7321 aacgattggg aaaccagtta ttttcgttca acacgaagat gctcaattag tgccacaaac
     7381 aaaaccatgg gagctattgt cggaattatc tattcctgag cacagttatt ttgtgagaaa
     7441 aacccatgcg aattcatttt ataagactaa tttgagtgtt ttattaactg aattggactg
     7501 tcattcgatc gaattatgtg gggcacaagc agagtattgt atagatacga ctgtgaagtt
     7561 tgctcatgga ttaggatacc agcttatgat gtgtagagga gcaacgacaa cttatgataa
     7621 tccttttatg aaagcaaagg aaacaatcgc tttttacgag aaaatttggg ataaacgatt
     7681 tctgacattt ttggagcaat aagttgtttc ttcgtttaaa aaaagcagaa tggatactgg
     7741 tttatccatt ctgctttatt acgtaaaatg agaaaataat cctgttctat ttttatggga
     7801 taaaccattt attttttgta taaaaaatgt ttgcgtttac atataattct cctagaaaca
     7861 taaaaaggag tgaatagctt gagaacaaaa caagtattaa agggagcgtt ggtcatctta
     7921 tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg gagagagcat ttcttccgaa
     7981 tcggaatctc gggaggtaga aaccacagaa actactgatg ctggaaatga aacgaaatcg
     8041 agtacttcac aaacagaaac aaatactgaa acaacggttg agacatctgt tactagcaca
     8101 gatcaagaaa cgaccgctac cacagataac caacaaacag aagaagcaac agctacaaaa
     8161 atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca aagagaatgg gacagaaaat
     8221 gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat atttgaatta cttcggtaaa
     8281 cagatgacag aaatacttaa tggaccaaca gaagacatca agtcaaaatt aatagagtta
     8341 ttagtcactg agcttgctgt taatgattat ggtgtagata aagagattat caaacatctg
     8401 attgctactt atctattgta cgatatcgct tttgcaaaaa acagtgtgtt gatgtcgatg
     8461 cttggaggta cagatgatgg gacaacgcct acagaaaaca caggcttcta tccaaataca
     8521 aaacaacttc atcaaactgt actaaacaaa caagatggca aaatgatgga tgtatatgca
     8581 tattatgtcg atcaaggttc agataaaaca gtcatgatcc atggcggatt tcgagggaat
     8641 tggaataacg ggatcgttac agaagaatac aatgattttt ataaggccgg gtataattta
     8701 ttatttgttg attccagagc gactggtaat agcggaggcg attatgtgac ctatggacaa
     8761 tatgagtcag atgacgtcct ttactggata aatcaagaag ttcgagagcg gccatctcaa
     8821 aagattttac tttatggtgg ttcgatggga gcagctacga tgatgtctgt attagcgaaa
     8881 gatattcctg tcaatgtcaa aggaattatt gaaaattgcg gatttgcatc aattgatgaa
     8941 caactacgtt ttacgtacag ccagacagta gcccccgcac taccggatgc cataaaaaat
     9001 cagttagaca tcattgggga tcaagagcat gaagatttat ttatgggcct tttgaaacaa
     9061 tactattttg atcaggagat gcatttggat acaaaagctg ctctacctac gattggaatg
     9121 tcagattcat tgcctaaatt gattatccat ggaacagcag atgatgtagt acctgtgtct
     9181 aacgcgcaaa aattatatga gttatcagga gggtataaag atcttttatt agtagaagga
     9241 gcagggcatg gaaaggcaca ggaagttgac catgctgcct acacgaaaca tgtaacggac
     9301 tttttgaaag tagtgttcca tgatcagata aacgtaaagt atgtggatga aaacaataaa
     9361 agtctactca aagaccagga cgaaatccag ctttacggag cttatggaga aaattatatg
     9421 acagagcaaa agacattcga aggatacgaa ttagcaaatg ttgaaggacc gactgaaggg
     9481 atttttaatg agacgatacc aactattatt ttctattaca aaaaaatccc agtagctcca
     9541 ccaaaaaagc aagatccgac agagaatgca gacaataagg gaaagaatga acctcgagag
     9601 gatcaatcaa gtgatgatac gcaaccgatt cagatgacag tgaaagtaca aaaaaagaca
     9661 gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga aacattcgct tctcatttat
     9721 tcaggtggat ttttatctgt tagcacgatt atcacatgga tttggcgaag aaagagaggg
     9781 taaatgaatg aaatggttca agcgaatagt gattgcagta ccagttatca tcgtagttat
     9841 tttagtcact gtatttttga ttaatcaaat cacaccaaag ccgattagct tgcttgttag
     9901 aaaacaattt gacacaagtg aaaaagaaca agtatatgcc cgaccagatg atttccagca
     9961 aaaaatcgaa caaatcgata taaaaaaaga aatatcctat ccttcaaagt acaaaaataa
    10021 taatatggat atctacacac cgaaagtgga aaagaaaaaa ttaccgattc ttttctggat
    10081 gcatggaggc gcatatgtag gaggggataa aaatgattgt cgtgattatt tggaatatct
    10141 atgttcagac acgcagcaaa tcatcgtaaa tatagattat gaacgatcac cggaagcaaa
    10201 acatcctaca ccagttatcc aattgaacga agccattcaa gcagctaaaa aagagataaa
    10261 agatcaagca gattggtcga atatttcgat tggtggaaat tcggcaggtg cacaaattag
    10321 tggagaatat ttgttagcac ttcaaaatga agaaattaaa aaagctgatc atcttgatcc
    10381 gactttggag aacaagcaga ttacgaagtt tatttctttg tctggtctgt tggatccttc
    10441 tgcacttact caagtaagtg ataaaatctc tagctttctt tatgaaaaat gtggatgggc
    10501 ttactttgat aataaggact ttgaacaatc agagaaggtc aaaagtttag ccttggtcag
    10561 acatgcggat cgttggacgc aaaacacatt cttaacggat ggaaatacaa atacgtttac
    10621 gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg ggggtgaaag tcacaaaagt
    10681 agattatgcg gagaaaaatg ctgttttgaa ccatgaatat cagtttgatt tcagcaataa
    10741 acaagcgcaa gaaacatatc aaaagttagt aatgtttttc aaggagtaaa gtcttatgat
    10801 gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca aggagcaatt tcaataaaca
    10861 agcttttcat ggtttatgaa tattgtaact tgtgactgag gagttagaga tggcaagggg
    10921 caccttttat tcgaaatttg ggaatatcac acgattattg tcacgatctc ttttacgtaa
    10981 attttataag tcagatttgt tgttttgatc gtttaaaaaa agcaacaaat ccgaagcctg
    11041 cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa gaatgctggt tccactaata
    11101 ttccgttgtt attgatataa ggctgggaac aaagatgaat agcaaataaa atcaatgcac
    11161 tagcgaaaaa aagcaaagaa atatggatag ctttcataag cagcacctcc ttttttataa
    11221 ttgtatgata aatagattaa gaatctataa atgtgacaag tttgttagga tgtgaataaa
    11281 atgatcatct agcgaacttg aaacaaagat ggctaatgat aagcaattaa tgattcagca
    11341 atcagatagg tacaaagttt accatcatac gtctagacca ataatagaaa atatgggaat
    11401 ataatagaaa agatttagga tacccccaaa agaatttccc caaaaattcg atgtatccta
    11461 aactttttta ttttacataa caatcatatc aactgtgaaa taaaattaca aatgataacc
    11521 taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt aattcaccaa aatttttttt
    11581 aattttttag aaaataagaa acaaaaataa taaaaaaaag aaaagataaa ttttttacta
    11641 ctgtatacta actttgttat cgcatctaac aagtaactcg aataatacca atacaacctt
    11701 ctccaaagat gcgatgacat acgttctaac ccaccgacta ttgatgttct gtaccaccct
    11761 tgcagaacca aaaaagccac taccaaatat ttggtagtgg ctttttttgt tttatggatt
    11821 tttcgctttt tctgttatgg tgctattctt tgatttcaga aatagtatgt cgaactttag
    11881 cgatagaacg acgtgattct ttttcgttgt aaaacatcaa aatcacatat agagagtcca
    11941 aaatgcttag ttgagaaata cgggaagcta aagcttcaga tcggaattct gtttcttcag
    12001 aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga agaattagct tggctagtaa
    12061 taacgattgt ttttgctcca gtttttctta cggtttcagc aatatggatt gtttcttttg
    12121 attgccctgt gtgagaaatc aaaacagcac agtctttttc cgtcaataaa gaagcttcca
    12181 tcaattgaat atggtaatcc gtgctgtgag aagttgcgat aggggaacgc aaaaatttat
    12241 gataagcgtc agttgctaca atctctgaac cgccaacacc gaaaaaatag acacgtttag
    12301 attcattgat aatagtagcc gcttttttta gatccttttg ttgtaacaac ttttttgtgt
    12361 catttaaagt tgaaatacta gactcgaaca ccttttgcgc catagtgagc tcagtatctg
    12421 ttttctgaat attttcgtgg atagaaatag cagatagatc attttcttgg atcaacatgg
    12481 ccattttaaa atctttaaat ccattataac caagtttttt tgtaaattga aaaaaagtag
    12541 agtcagcaat gcccagttca cttgctaaat tgctaatagg actatgactt actttgcttg
    12601 gattttctaa aatataatcg gcgatagcct gttcttttgg gctgaagtcg ttgtacattg
    12661 ttttgatttg tagtcttatg gagacgctca tgagaattcc tcattttcat aataagatta
    12721 tcattttttc cgttctcatt aatgttaaag atacaaggag agtaggaaaa aatcaaacaa
    12781 aaaatatttt tgtaaaatct atttacaaaa aaattttttt gtataatgag ggtataagaa
    12841 atggaggcgc tatcatggaa attggtgtaa ttggtttggg aaaaatggga ttgaatttag
    12901 ctttaaactt aaaagagcac catcacaaag tacaaggact cgacatttca agtacagctg
    12961 ttagtcaggc aagagaaaat gacattcctg cttatcaaga gatctctgaa tttctagcta
    13021 cttttgagca gaaaaaaatc atctggttaa tgcttcctgc tggagagata accgaaaaca
    13081 tgttaagaaa actttttcca aaactcggac caggagacat tattattgaa ggcggaaact
    13141 cttattataa agattcaatc cgtcgagcag aagagtttca gaaaaatgaa atcggttact
    13201 tggattgtgg gacttctgga ggaatcgaag gagcacgaca tcaagcctgc ttaatgattg
    13261 gaggagataa agaaactttt ctatccgtgg aacaattatt caaagatgta gcaattgaaa
    13321 gaggatatct gtatgctggt gcatccggaa gcggacactt cttgaaaatg atccataatg
    13381 gaatcgaata tggaatgatg caagcaatcg gtgaaggatt ccaacttgta caaaaaagtg
    13441 agtatgcttt tgacttggaa caagtcgcac gtgtttggaa tcatggttcg gtgattcgcg
    13501 gctggctgat ggaaatcatg gaagatcagt taaacgaaca tcccaattta agtaattatc
    13561 ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt tgaaacagcg ctagaaatgg
    13621 ctgttccagt tccagtaatt gcaactagtt tgttcatgag gaatctttca caggaagaag
    13681 atagtttttc agcaaaagta gtttcagcac taagaaatgg gtttggcgga catgaaatag
    13741 ttgaaaaggg tgagtaaaat gccagattat catatagcaa tcgttaattc cagcagtttc
    13801 ggaagagtct ttccacacca cttggaaaga ttaaagtcag ttggagacgt tcatttcttt
    13861 actgttgatc aagagattcc aggaaaagaa ctagcggagt tacttaaagg attcaatatc
    13921 attattgcaa gtgttacgcc attttttcga cgagattttt ttgaaaacaa agatgaactg
    13981 ctattgattt cccgacatgg tattggttac aacaatattg atttaaaagc agcaaaagaa
    14041 caccagacaa tcgtatctat catacctgct ttaattgaac gaaatgctgt agcagaaaat
    14101 aatataacta atttgttgtc catgcttcga cgcacgacac aagcacaagc aagagtcaag
    14161 gacgatcgat gggaagatcg ggcggagttc gtcggtagga cgctgtttaa caaaacagtt
    14221 ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg aaattttgcg taacggtttt
    14281 cgctgtgatg ttctagctta tgatccttac aaatcagatt tatacatcga aagctttggt
    14341 gcaaaaaaag tagaacttca agaattactg gaacaatcag atatcatttg tttatgtgcg
    14401 aatttgacag aagagaacta tcacatgatt tctgataaag aagtcgatca gatgaaagaa
    14461 aatgtttatc tatctaatag tgcaagaggc gctctagttg atgaagaagc gatgattaat
    14521 ggtctgaaaa gcggaaagat cgcaggatat gccacagatg ttttagaaga agaaccggga
    14581 cgtcaagatc atccgtattt agcgtttgaa caagtagtga ttacgccaca tatatcggcc
    14641 tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg tcagagatgt cgaacagatc
    14701 agtcagcacc ttcttcctga acgttctgtc cagacaaaga gcaactatat aaaaggatga
    14761 tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc tcaattttat ttatatgaag
    14821 aaggtggtat ttcaaaagtt tctgatctct tgaaatcata cggcgcgaaa agagtactgg
    14881 tcacccacgg aacggtatca tgggaaaagg cgctacctaa attagtattt ttgaatgacg
    14941 aaacgattca atttttttat catcgttatt ctggagaatg tagttatgct gaagccagac
    15001 gaatagctac aatcatcaaa aaaatgaaat cgatttcgta gttggcgttg gcggaggaaa
    15061 actgaccgat ctagtgggtt atagtgccaa tcttgcaaga atcgatttcg gagtcatccc
    15121 tactttagct agtaattgtg ctccatggac acctcttgct gtcatgtata aggagaatgg
    15181 acaagcagaa gggaaaacag aacactttta cagacaagct gcttttttta taacagatcc
    15241 ccaattagtg attgattccc ctgttccata tttcattgcc gggttagcag atacactagc
    15301 aaaatggtat gaatctgagc tcatcttaga acaagatttt ttgcaagatg aatcattttt
    15361 gaagctagca caagatactg cgaagatctg caaagaagag attttgaatc attctgctaa
    15421 agcaatccaa gatatggcac aaagaaaact gacatcggag ttcaaacagc tttcagagat
    15481 tatctttgct gttgctggtt tagttggagg attaggagat aaatacgcaa gaaatgcggc
    15541 agcacatgct atgcatgacg ctatcagtaa atatattccg gaaagccatc gttttctaca
    15601 tggagaaaaa gtagcgtatg ggattttcta tcaactggca ctagaaggtc gctgggaaaa
    15661 aatagacgag ttatatcctt tgtatcggga attagaactg ccggtttctc tagaacaaat
    15721 gggattattt ccgaaagata aacagataat agataaaatg gctgaattta ttgattcgaa
    15781 agagaaagtg catttgattc ctatagaggt aacacagaaa tcactgatac agtcaatgat
    15841 ggaactggaa ggttatatca gaaagatctg aaggaggagg acacatggaa acattaagtg
    15901 tagtacaaag tttgttgatt gctttatggg tagccgcggt tatgtcccgc tggttaggtg
    15961 gaggagccac gttgacctta cgtttttctc ctttgatgac tggattagtc gtcgggttga
    16021 tcatggggga agttgcacaa gcgatgattg ttacagccgc tttgcaaatg atttatatgg
    16081 gggttttttc tccaggagga tcaatgccag ctgaaccatc tattgcagca gctatcgcag
    16141 taccagtcgc attattaggg gatctgtcgc cagaagcagc gattgccgtt gcggtgccag
    16201 tcggattgct cggaagttac ttgtatcagt ttcgtttttt catcaatact tttttaggta
    16261 aatatacaga caaagctgta gaagatttga atacaaaagc tatggcccga tcaattattc
    16321 tttatccaac ggttgcctca tttttattat tcgttccgct tgttttcatt gctttatatt
    16381 taggggcgcc attgatcgct gatgtaatca aagctttaga gggaacagtc gttatccaca
    16441 ttcttgaagt agtaggtgga gggttagcgg caatcggtat cgcgacaact gtatacgtta
    16501 tcggtcgaaa agattatctg gtctttttct tccttgctta ttttatgagt gttgttttga
    16561 aatctttaga tattacgatg gttacttatg ccatttttgg gattattatc gctttgatct
    16621 ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac aagcaataac aattcagcat
    16681 cttttgatga cgaagatgac tatgatgacg gattttaatt taggaggaat gggaaatggc
    16741 tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag atgtaacaaa
    16801 agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac gttacttggc
    16861 gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag atgaagactc
    16921 tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa gctggggtgg
    16981 cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag aagagtatga
    17041 agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg gattgatggg
    17101 ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata tttttatcgc
    17161 aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc cttttatctg
    17221 ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt tcactatggg
    17281 ccgtaatgct acaggcctaa tgcaaaacac tggtgttcag acagcgattg aaatgctatc
    17341 agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag tagaatcttc
    17401 attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg atcaaatcgt
    17461 gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata cgaaaaaagg
    17521 attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc tagcaggaat
    17581 cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt tagcgcgtgt
    17641 ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa gtggagtgaa
    17701 ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag atctttacaa
    17761 aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga aagctaaatt
    17821 ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa aaacagtcca
    17881 aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata ttggagggat
    17941 tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt taaataaatc
    18001 agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata tttattttca
    18061 agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt ttgatttgtc
    18121 ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga acgagctgtt
    18181 tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa aaaagagtaa
    18241 acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag atgtgacagt
    18301 cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag atatcgaaaa
    18361 agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag gaagttattt
    18421 catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat tgtccttcat
    18481 tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc ctcatcacgt
    18541 attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga gctacttttt
    18601 cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc gaaatacttc
    18661 atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg tagcgtatgc
    18721 gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat cgggtatgaa
    18781 aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc tacagttttc
    18841 gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt tgaaagaaaa
    18901 aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct atttgaccaa
    18961 aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta ttgctctttt
    19021 tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa tcatgatcgt
    19081 tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg tcgggacatc
    19141 gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat tcggagagaa
    19201 ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat ttgttgatct
    19261 aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga ctgaagaaaa
    19321 gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag aagcaatcaa
    19381 tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca aacaaggaaa
    19441 agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg aggacgattt
    19501 ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa aaaggggatt
    19561 cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt ggaactttgc
    19621 tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg aaagcatctg
    19681 ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac gatgcaatca
    19741 aggcagggac agatgaacga gattactata ttgataacta tatacgaaca atcaaaaact
    19801 tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt ggatgggcga
    19861 aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac gatcagaaaa
    19921 tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag tcaaagggat
    19981 tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg gaaaaactgt
    20041 atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta gaaaaagtga
    20101 ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat ccgccatggg
    20161 aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa attctaaatg
    20221 cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg gcaaatccgg
    20281 aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt gtccacttca
    20341 gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc tctacagaag
    20401 gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc gacggtccta
    20461 tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga tatggcctgt
    20521 atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata agtaaggaaa
    20581 aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat ggatggcctt
    20641 ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca aaagtatgat
    20701 tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat ggcgataaga
    20761 gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg agaagcaatc
    20821 aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa aaaaggagca
    20881 gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc ttcgtctaat
    20941 acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt gtttgatcaa
    21001 atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt tttgaaagct
    21061 tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc gattgcaggg
    21121 atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca tttgataggg
    21181 ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata tgaatccaat
    21241 aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga aagtaaaggg
    21301 ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc ctgcacgact
    21361 gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt atttgtagtg
    21421 aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat gcgtttaaag
    21481 agaagaacga gaatcgtcca tatgagggtt tccactcctt atgcagattt ttttaattct
    21541 tgcactgctt gttcgatcgt aacacctgtc gctacatgat tggtattttc tttgtcaaaa
    21601 acgacaaata gattcaaatc tgtatccaag gttactcgat attgtatatc tttgttatag
    21661 aatgtcatag ccattctcct ttctttaaat acttgctgaa aggcaacgaa cgcgttgata
    21721 acgaaattcc atttataagt ataccaccaa ttgaaaggtt ttcatagtta agaaatttta
    21781 aagtcaaaag ttgcagataa aagcaaataa acaagaaaac aaaaagtgaa tcaatcgcgg
    21841 ttattcaact ttttcttcga ttcgaagaca atagaagaca atgaatttta tatttcattg
    21901 cattatcctt gtgttattag aaaaagcatg atatattaaa tgagtaatct attttgaaac
    21961 gtaatttgag cgatatatct acatagataa aactcctttt gcctatcaaa tatttattgc
    22021 aacgaaaaaa cgtacattga tacgtatcag gaggaattta tttatgaata acggtacagt
    22081 aaaatggttc aacgcagaca aaggttttgg ctttatcact ggtgaagatg gaaatgatgt
    22141 atttgcacat ttttcagcta tccaaggtga cggcttcaaa actttagaag aaggccaagc
    22201 agtgtcttac gatgttgaag atggtcaacg tggccctcaa gcaacaaaca ttgttaaagc
    22261 ttaataaaaa ttgactttta accgtctttt cgaaagaaaa gacggttttt ttgtacgaaa
    22321 aaat
//
LOCUS       DADVXE010000043        22174 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.044, whole genome shotgun sequence.
ACCESSION   DADVXE010000043 DADVXE010000000
VERSION     DADVXE010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.044"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            240..2075
                     /gene="tdc"
                     /locus_tag="KB913_001808"
     CDS             240..2075
                     /gene="tdc"
                     /locus_tag="KB913_001808"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBB6820167.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            2380..3858
                     /locus_tag="KB913_001809"
     CDS             2380..3858
                     /locus_tag="KB913_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6820168.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            3824..5155
                     /locus_tag="KB913_001810"
     CDS             3824..5155
                     /locus_tag="KB913_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6820169.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            5269..7821
                     /locus_tag="KB913_001811"
     CDS             5269..7821
                     /locus_tag="KB913_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBB6820170.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(7828..9267)
                     /locus_tag="KB913_001812"
     CDS             complement(7828..9267)
                     /locus_tag="KB913_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820171.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            9613..9975
                     /locus_tag="KB913_001813"
     CDS             9613..9975
                     /locus_tag="KB913_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBB6820172.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(10162..11019)
                     /locus_tag="KB913_001814"
     CDS             complement(10162..11019)
                     /locus_tag="KB913_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6820173.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            11139..12050
                     /locus_tag="KB913_001815"
     CDS             11139..12050
                     /locus_tag="KB913_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBB6820174.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            12057..13708
                     /gene="mdcA"
                     /locus_tag="KB913_001816"
                     /pseudo
     CDS             12057..13708
                     /gene="mdcA"
                     /locus_tag="KB913_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
     gene            13810..14109
                     /locus_tag="KB913_001817"
     CDS             13810..14109
                     /locus_tag="KB913_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBB6820175.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            14099..15775
                     /gene="mdcD"
                     /locus_tag="KB913_001818"
     CDS             14099..15775
                     /gene="mdcD"
                     /locus_tag="KB913_001818"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBB6820176.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            15779..16372
                     /locus_tag="KB913_001819"
     CDS             15779..16372
                     /locus_tag="KB913_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBB6820177.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            16396..17472
                     /locus_tag="KB913_001820"
     CDS             16396..17472
                     /locus_tag="KB913_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBB6820178.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            17497..18366
                     /gene="mdcB"
                     /locus_tag="KB913_001821"
     CDS             17497..18366
                     /gene="mdcB"
                     /locus_tag="KB913_001821"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBB6820179.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            18477..19241
                     /locus_tag="KB913_001822"
     CDS             18477..19241
                     /locus_tag="KB913_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBB6820180.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            19730..21823
                     /locus_tag="KB913_001823"
     CDS             19730..21823
                     /locus_tag="KB913_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6820181.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            21848..22150
                     /locus_tag="KB913_001824"
     CDS             21848..22150
                     /locus_tag="KB913_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6820182.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
BASE COUNT         7178 a         3788 c         4725 g         6483 t
ORIGIN      
        1 tgtttgttcg ctttttttag gttatctatt ttagaagact gatttattga aaaattgttc
       61 gcttttttgc gttgaattat cagaaaaatc cgactttatt tatttttgtt tgtaaaaatc
      121 tacgtggatt tgatgttata aaaaaaaaat tctcattttt ggcgctatag tgaagaggtg
      181 ttacagataa acacatgtat ctgcaagaca ttgaccaaca aaatatggag ggaagaaaaa
      241 tgaaagatat ggatatcaag gccgtcttta taggcgacaa agctgaaaat ggaccagttt
      301 ataaaatgtt gttgaacaag atggtagatg aacatcttgg atggagagaa aattatattc
      361 cttcagatat gcctgcaatt agcgaaggag ataagctcac tccagattat ctagccaccc
      421 gcgaccatat gatagaggtc ttggatgaag tcagtcagcg attacgcgca ggatcgatcc
      481 catggcattc agcaggccgt tactggggac aaatgaatgc tgaaacattg atgcctgctt
      541 tattagctta caactatgcg atgctgtgga acccaaataa tgttgcattg gaatcttcta
      601 tggcaacttc gcaaatggaa gcagaagtag gacaggattt tgcttcatta ttcaatatga
      661 cagacggatg gggacacatt gcagcagatg gttctattgc taatcttgaa ggattatggt
      721 acgcccgttg catcaaatcg attcctttag ctgtcaagga agtgctgcct gaaaaagtga
      781 aaaaaatgtc tgagtgggaa cttttgaatt tatctgttga agaaattttg gaaatgaccg
      841 aaagctttac ggacgaagaa atggatgagg tcaaagcagc ttcttcccgt agcggaaaaa
      901 atatccaaag attagggaaa tggctggtcc ctcaaacaaa acactattct tggatgaagg
      961 cgttagatat ttgcggagtc ggcttagatc agatggttgc tatcccagtt caagaggatt
     1021 atcgaatgga tattaatgct ttggaaaaaa caattcgtga attagctgga caaaaaatcc
     1081 caattctagg tgtggttgct gtcgtaggaa cgacagaaga aggtcaagta gacagtgtag
     1141 ataaaatcgt ccaattaaga gaaaggttaa aagatgaagg gatctatttc tatttacatg
     1201 ttgatgccgc atatggcggc tatgcgcgtt cactgtttct aaacgaagca ggagaatttg
     1261 tgccgtatgc ttccttagct gaattctttg aagaacatca tgttttccac cactgcgtaa
     1321 cgattgacaa agaggtatat gaagggttca gagctatttc agaagcggat tctgtcacga
     1381 tagatcctca taagatgggc tatgtccctt atgctgctgg aggaatcgta atcaaacata
     1441 aaaatatgag aaatatcatt tcttatttcg cgccatatgt gtttgaaaaa tcagtaaagg
     1501 ctccagatat gttaggagct tatattttgg aaggatcaaa agctggagca accgccgccg
     1561 cagtctggac agcacatcgt gtattgccat tgaatgtgac cggatatggt caattgattg
     1621 gggcttcaat cgaggcagct caaagattca gagaatttct cgatcatctg acttttactg
     1681 ttaaaggaaa aacaatcgaa gtctatccat tgaatcatcc tgattttaat atggtcaatt
     1741 gggtattcaa agaacaaggc tgtacagatt tgaacgctat caatgaatta aatgaaaaaa
     1801 tgttcgatcg gtcttcttat atggatggcg atgtttatgg tgaacggttt attacttctc
     1861 atactacatt tacacaagaa gattacggtg attctccgat tcgttttgtt gaaagaatgg
     1921 gtctaacgaa agaagaatgg aaaaaagaac agaaaatcac tctgctacgt gcggctatca
     1981 tgactcctta tttgaatgat gatcgaattt tcaattttta tacaaaaaaa atcgccaaag
     2041 caatggaaaa gaaactaaac gaaatcatcc aatagaactg atttttgtgt gaaagaataa
     2101 caagagacat atggagaaca gacaattatt tgcttcatca aaacaattgt atttccccct
     2161 gtttttcata tattcctcgc caagatattc ttttttataa aacgttctat aagttggatc
     2221 gttcgtttca tgtatcaaac ccagttcact aagatcgttc aatggatgtt tcggtgatac
     2281 tgggttttgt actgaatcga tgaaaccttg tcatttctgt tcttgaacaa aaataaaaga
     2341 aaacaaaaac atatgtcgct attgaaagaa ggaataaaga tgaaagatac tggttcatca
     2401 aagcaaatca cgaccatgac ctttatcgga atgacctgcg cccttgtagc aagtgtacga
     2461 aatattccag atgtagcagc aacgagctgg acgatgattt tttacatgct ggttgcagta
     2521 ttattgtacg cttttccaat ctcattgatc tctggtgaat ttgctggaat gtttccccaa
     2581 aaaggtggtc cagaactttg ggtatcgaat gctctaggaa aaaaatgggg gttcgttgtc
     2641 tcatggctgt tatgggtcca aatgtttcct gggatggtga tggtcgcttc agcactcgct
     2701 ccgttgtttg gtaatattat cgataatgtg ccgcttggtt tgaacagcaa atttacatta
     2761 gttgtcattt tagtcgttta ttggatcatc acttttttga atttgaaatt tgatatggca
     2821 aaaatcggcg gaaaagtcgg tgtttggtta ggattgtacg tgcctttgac gatgatgctc
     2881 ttattagggt ttgctgcgtg gatcaaagtt gggatcgtac caaccggaac attaggcagt
     2941 ttttcatggg acaaattaat accagatact acgactgcat cctcatttgt ttattttgcg
     3001 ccgatcatgt ttatttttac tggtatcgaa atgtcctctg tgtatatcac tcgattggaa
     3061 aatccagtta aaacgtatat tcgcggagta tttgccgcgt taatttttat atttttcgtc
     3121 aatattttga atgctttagt tgtagcaaat gtcgtaccaa aaggacaaat ggaattgaat
     3181 aatatcgcgc aatctatttc gatttattgc caaattcttg gtttgccaca tcttattgtg
     3241 aatctgttta gtttacttgt cttcattggt gtagcagtcc aattatctgc ttgggcctca
     3301 ggaccagcaa agacagtgac agaaagtgct agaaaaggtg cgtatccacc aaaattcaat
     3361 ttttggaaga cgaatcaatt tgacgtatcc aaatccgtta ttttgactca gtctgtcatt
     3421 atctcaatct ttgcactttt ttatttgctg attcctggcg tcaatcaagc atttttgatg
     3481 ctcgtaaatt caactactgt tatctactgt atcgtctatg tcatcatggg gatcgcagtt
     3541 ttgagattgc gttatacaca tgcaaagttg aatcgaccat ttagaattgg aaaaaaagag
     3601 aaaaagagca atcttggagt ttggactgtc gttattgttt tatttgcggc aatcggattt
     3661 tctgtcggac tgacgatgaa agctggaaca tggatcaatc taattgcagt cacagccatc
     3721 agtgtcattt tgtttgtagt accactctgt attgaaaaaa taaagaaacc ttcttgggaa
     3781 caggaagtcg ccatgctgct tgaaaaagaa aaaggtgaac ttgatggaaa aaccggcaat
     3841 gaaacggact ctaactaatc gaaatatcca gttaatcgca ttaggtggcg caattggaac
     3901 aggattattt ttaggttcag caaaggcaat tgcatcagca gggccagctg ttattctcgt
     3961 ttatttgata tgcggtttgg ctatttatgg tttgatgcgg gccatgggtg atttattttt
     4021 agcaaatagt acatttaact ctatcagtga tttcgttgac tattatttag gcaaaaagtg
     4081 ggcatttttt gtcaattgga cttattggct ttgctggctt ggagctggac ttgcggaatt
     4141 aacagcaata ggattgtata tccatttctg gtttgtacat gtaccagctt tgataagcgg
     4201 aggtagcgca ctaatgatct taatggcagt caaccttgtt gcagtcaagt ggtttggtga
     4261 attggaatct tttttctcaa tcatcaagat cttggggatt ttccttttta tcttattggg
     4321 tataggattg agtgtctcag attttcatac ccagtctatc ggaatcaaag aaaattttgg
     4381 acagatcgat gaattactac cgtttggctt tgctggaatg gtagtctcat ttcctatggt
     4441 tttattcagt tttgctggaa ttgaaatgat cggcttaacc gttggcgaga caagtgatcc
     4501 gcaaaagaat ttgaaaaaag caatcaactg tctgccttgg cgtattctct ttttctatat
     4561 aggaacgatt ttgtcgattt tatttgttgt tccatggcat tgtttagatt taaaagaaag
     4621 tcctttagtg actatgctgc aagtgatcca ttgccaaggc ggagcagcaa ttgtcaatct
     4681 aatgattttg gttgcttctt tgtcctcagc aaatagtgca gtctacagta ctagcaggat
     4741 tttatatcaa acagcaaaag aaaaaagttt gccccattgg ttttgtgcgc tttctaagaa
     4801 aggcgtacct ttacacggta ttttaattac aggaatgtta ttttttgccg gtctttgtct
     4861 acattttttt gtagctgata gtcgattgtt ttttcagctt ttggcaggca tgacaacgag
     4921 ttgttttcta tttgtgtggt cttcgatctt gtgtgcacat gttcaattta ttaaagaaaa
     4981 gaaacggaac actacacaaa gatataaaga tcttgctttg ttggtgtttt ttacttcaat
     5041 tgctttcagc ttgttattcg aaagcacgac acgctttatt ccttttttat tggttatctg
     5101 gtttgtattc ttaaattttg tatataaaag aataagcaat agaaatatca gttaggccca
     5161 gatacatttt gcaaaacgaa ttatttcaga cccccctgaa ataatcgata cgcctgaaaa
     5221 aacttccctg cgtataataa cagtatcaat taaacaggag gggataggat gaactggtac
     5281 agattgacgg tagaagatgt attgaaaaac tatcaaacat caacagaagg cttgtcgcaa
     5341 gaagaacgac agaaacgcct gactgatcaa ggatataatg aaataaaagc aaggcagcag
     5401 acaaaacgat ggaaaaaaat agcaaagcat tttactgatc tgctgatgat cgtgttgatc
     5461 attgcctctt ttttgaaatt tgcttctagt gaatatattg aaggaagtat tattttattc
     5521 gtagtgatcg tcaatggact cgttagttac tggcaagaaa gaaaagcgga agaatcattg
     5581 aatggtttga agcagctgat gggacaagaa gcgatagtac tatcaaacgg gatgcaagaa
     5641 aaaatccctg cgaaagaact ggtaaaagga gatgtcattg tcttacgtgc cggagatgtc
     5701 gttccagcag atatccgatt aatcgaagca catgatttat tagtggaaga atcgattttg
     5761 acgggagaat cagaagcatc tgaaaaaagt catgccgttt tgacagaaga agaatcgatc
     5821 ggcgaccaga aaaatatggg tttttcagga acgcttgtac aatctggttc tgcagtcggt
     5881 gtcgttgtag aaacaggaaa cacgacagaa atcggtaaaa tcaatcaagc attgcaatcg
     5941 gtcgaacaac aaacgacgcc tctgattaaa aaaatcaacc gattaaacaa acaaattttt
     6001 caaggcattc tttgtttgag cctattctta gttattttta cgacatttcg atatggtatg
     6061 gattggcata tccttctttc ggctacgatt gctttggtgg tgtcaatggt acccgaagga
     6121 ttgccagctg ttttgaccat gattctatcc gttggagtac atgaaatggc aaaagaaaag
     6181 gcgatcatca aaggacttcc ttcggtagaa acattaggtt ctatgacagt gatctgttca
     6241 gataagacag gaacattgac aaaaaatgaa atgacagttg tggatgtagc tgcaaaagaa
     6301 gaagcctgcg tgttgtccat tatgaaaaac tgtcaggaat taaaaacaaa agaagaacag
     6361 aaaacagaaa atttaagtgg caatccgaca gaagttgcgc tgattcgaca cacagaaaca
     6421 gccaatctac ctttgaaaaa aatagaagca aagattccgt tcagttctga atacaaatat
     6481 atggcaacga tgcatgcgga ggaaaaagga gcggtgattt acgtcaaagg tgcaccagaa
     6541 gtattatttg ctaaatcaac tctttcttct gcagaacaag aagcatggag tcagacagct
     6601 gcagaatttg cgagaaaagg tcagcgtgtt ttaggatttg cttataaaaa agtagattcg
     6661 aaacaggaac tcacgcatga gactttaacc caattaactt ttgcagggat cgccggattg
     6721 atcgatccgc caaaagaaag tgcagtcaaa gctgtaaagg aatgccaaca agcagggatc
     6781 tcagtgaaaa tgattacagg ggatcacaaa gacacagcaa aagcgattgc ggaacaaatt
     6841 ggcttaaaac atactgccaa agttttagaa gggatcgatt tggatcttat gtctgatgaa
     6901 gagttgattc agcaagtgcc aatagtcgat gtctttgctc gaacgacacc agaacataaa
     6961 ctgcgaattg ttaaagcttt gcagaaaaat ggagaaatcg tcggaatgac cggagacggc
     7021 gtaaatgatg cacctgcttt gaaaagatcc gatgtaggaa ttgctatggg aatcaaaggt
     7081 agtgaagtaa gcaaacaggc agctgatatg gttttaggag atgataattt ccatacgatt
     7141 gcaaaagccg taaaagaggg ccggcggatt ttggataatt tgcaaaaaac catcaatttc
     7201 ttcttgccaa ctgcattagc tcaaggattg atcttgattt gggcacttat gctgaatcgc
     7261 ccgctacctt tgtccccagt acagatttta tgggtcaata tggtaacgac aatcacttta
     7321 tcttatgcac tagggttcga gtcgccagat ccagaaatca tgaagcgccc accaagagat
     7381 ccaaagcaag gaatcctatc tggttatcat ttgtttcgga tcatctatgt ctccctactg
     7441 atcatggttc ctgcctattt attggctatg cagtttgaag ggcaaagctt acagcaaacc
     7501 attcttctgc aaaatatcgt cttagctcaa gctgtttaca tgatcaattg cagagagttg
     7561 tccaagccgt cattgaacca aggtcttttg caaaacaaag cgctttttct ttcattaggt
     7621 atccttgctt tattgcaagg gatggttatt tttctaccag tcggccagca gctgatcggt
     7681 acagtaagtt taacgatgac acaacagtta ttgattggag caaatgtgat tcttctattc
     7741 ttagttgtag aaatagaaaa agggatcatg aacaaactgt ttcgcaaaaa agaaaaaaca
     7801 gctagagaat acagtcgcta gccgttacta taaaaaagtt ttgaaagtga gttcagtcaa
     7861 acgattgagc tcatttttcg ttggaataga agaaatgtat acaataggga tatctagaga
     7921 atctagaggg aaattggaaa tcaagatatc tgttttttca aaagaaatag tggaaagatc
     7981 ggttagttcg ataggtaaga agcagacacg ttttcctaag taatctttta attcctgctg
     8041 caagaacgcc ttccatgaag gttctccttg gaaaataaaa tagacattga acaaattcgg
     8101 tttgatagaa aaaatcgttt gttggatcag tagagacaag agttggagaa agtaatttgg
     8161 ttcattgatt tctatttctt tttttagatc gttcagtaaa ttctctttct gttgatacaa
     8221 gtgtgcatat tgctgatcat atgtttctaa aaaacgatgg tattgacggt ccaatgcttc
     8281 aatcaatatc ggcgattcat gatattttaa tatgaggaga gccaagttat cagtcagaga
     8341 tgtttttttt agttgatcaa gagacagctc tgaagctagt tcctctacaa acgtttcgag
     8401 gacctctaaa aatggagaat gatgcaggca gcgagcggtt tcttgtccat agttattgtt
     8461 gtaattccaa ctttccagaa agcagaaaga agcaaaagaa agctcagtgt ctttaagata
     8521 aataccttcc gttaaataca attttttcaa tgcagagtca tacagggagg agagtgtgct
     8581 gttggtatgg atagaagaat ctaatcggca attcgctttt atacggatcg tattgataaa
     8641 gaaccaacat gttccgaaaa tctcttctgt ttcaaccgct agttcagttt gactgaggtt
     8701 tcttaaaaat tgaaaataat gggattcatg gatcgaataa tcctcgaaaa aatagttgtt
     8761 atgagtgaaa ggaatcagca atcgatgata aaaagtacga atcgcacgct cttttccaag
     8821 aatacaagct gtatatttcg tcaaatcgat ctgcaagtcg taacttgcta aacgctgatt
     8881 gattttagtc acatgtcttt tcaatgtccc ataagaaagc ccatggtcgg ctagaaaatc
     8941 agggacagca actttttttg taaaaagcag atttttcagc agttcgacac tgactgattg
     9001 tttgaaaaaa atctcccaaa ggtcatttgt taataaattt tgctggtttt gcaaactgat
     9061 tcctgcttga tcgctgatga tgtcccagcc ttcgggcagc tgagagcgaa tagattgaag
     9121 gtcagaaaaa atcgttcgtt cggttgtccc tatgatttca gctaattcat ttacggttat
     9181 ctttgtatga ttcagcaatt gttctactaa agaaacatga cgtcgaatat ctttttcggt
     9241 aatgattttt ttcattagtg aatacatcaa tcagactccc ttctattcta agaatacgga
     9301 gaaaataaac ggtggtcaag tttcaactga tttttcaatc attgtttatt tttctggagc
     9361 atttactgat gataagaatt tcatcatgaa cttgaaaaat gataccacta aaatcaaaaa
     9421 ataggtgggc aaacaataat aaacatttta atagtagatg gtagcaagac caacacaggc
     9481 ggattgaaca tttaagagtt gataaaaaag aaaaatatcg aagtatttga ttagcaacta
     9541 cttgtattca tttttctatt cttacgtggt atctttgaat aaagcgaatc aataagaaag
     9601 agatggaagc agatgctaac gaaaaaagaa ctaatcgatc acatcaatga aacatacaat
     9661 ttgtctccag aatatatttt taaaaaattt cctgattatt gcgtattcag acatcaaaaa
     9721 agcaaaaaat ggtttggggt cctgatgtct gttccagaag aaaaaatcta tgatgatgca
     9781 agtgaccata ggatcatcaa tattcttgat ttgaaggtcg atcctgaact tggcggaatt
     9841 ttgcgaggaa aagaggggta ttttccagcc tatcacatga ataaagaaca ttggatctct
     9901 attgatctac gtaaaataga aaagctagat gaactagcag atttgattga tggaagtttt
     9961 aaatcaacgc aatgaatgtc taggacaata gagaagaggt tgtgacagaa atgtttagct
    10021 tcaagaaata agaaggaatt tacgaaaatt gcttctcaaa tttttgggaa atttcggctt
    10081 attttctaag aaattacttc tggaacaccg tttgttcgaa aaaagagctg cgacaagaat
    10141 tttgtcccag ctcttttttt tttattttcc taaataaaat tcccgcatcg tttttgcaat
    10201 cattttgatc aaaggatgat cttctgtgaa gctagaagat aaataaattg ttcgtgtcaa
    10261 gggcaaatct ttgatttccc gcaagacgaa aggatcattt ttatcgtaag accaagaaac
    10321 ttttgggaaa aagctaacag ctaatccttg cttgacaata gaacgtaatg tcgcaggatc
    10381 atctgtcgtc gaactgatcg tcaattcgat acttttcgct tcaagtgctg catccagtgt
    10441 atgacggaag gcgttgctct ttgacagcat caagatgggg gtgcgttgga tatcttctaa
    10501 ttgcagatgt tcttttttag caagaggatg tttcttagga atggcgacat aaacaggttc
    10561 tttcatgata ggaatattgg tcatgccagg cttcatctcc gaagtgatgt acagtacagg
    10621 atcggtaata tcatctggta aatgatgttg catgatcgtt aattggatat caggatgctt
    10681 ttccataaaa attcggacca agttcggaat agaaacagag gctacctcta aatacaatat
    10741 gacggaagta acgatcttct cattgaccga agacaataat ttgattcctt cttctaatgt
    10801 gtctaatgtc ttgactgcat atggataaaa ttcttctgca taaacggtcg tctcaatgtt
    10861 tctgccgcta tggtaaaaca aagggacacc taattcgttt tccaaatgtt tgatcgcacg
    10921 gctcaaggca ggttgagaaa taaataattc tttggctgct tgggtaacat tttttgtttc
    10981 gaatactttt ttaaaatact gcagatgaag caatttcata attatccatc ccatccatac
    11041 ctttttgtta tggttttttc tttttttggc attttttatt atagcagaaa ttgactaaga
    11101 tagcagtgga aaaagtaagt gctgaggagg cgaggctcat gagtacaggt ttcttatttc
    11161 ctggacaagg cagtcagaag ttagggatgt tagcggatat ccctgaaatg tacatggaac
    11221 gtttagaaaa tgtgacgggg tatcggttag ttgataaaga agaaaactat caagatacgg
    11281 tttttatcca gctagcatta ctgacaaaag cagtatttta tttagatgaa atggaaaaaa
    11341 acggtattca gcctgatatt gcagcaggac attcgattgg tgctttttgt gcagctgttg
    11401 cttgtcgatc tttgagattt gagaatgcag cggaactagt ctatcaccgc gcagtcttaa
    11461 tgaaagaagc ttatccaagc ggttatgcaa tgggcgtagt agtaggtgtg acgagaagcg
    11521 aagctgagga aattgtagca aaaacatttg atcctgacca tccagtttat ctgtcaaatg
    11581 aaaattgtcc gatgcaacat acgttatctg ggagtatcga aggtttatcc gttacgttgg
    11641 cagaagccaa acggcaccaa gcgcaaacag cgaagctgct gaaagtccct gtgccatctc
    11701 actgtctctt gatgaatgat acggtcaaga aattcaagcc gtatatgcag tctgtccatc
    11761 tatctgatgc tagatgtttg tatataaaaa atacggatgg aagagccact caggacgcag
    11821 aagagattcg taaagatttg ttggaaaacc tagctttccc tgtgcagtgg aaccaaatga
    11881 tggacttggc aaaagaatta ggaatggatc tgacgattga atttcccccc ggcaatactt
    11941 tgacaaagct gattcataca aaatttggtg tagataaagg gatccgtacg atcaatctag
    12001 accaacatgg tattgatgac gccacgtttc tatatcaaaa atggagatga ctaattatgg
    12061 aaaaaccaaa ccgcaactgg gcttctaaac gcgaaaaaaa agcgcagcga ttggaaaaaa
    12121 tcagcaactt gctcaatggc aagtatgtag aaactgaaaa aatcgtagaa gtaatggaaa
    12181 aactgattgc tcccggcgac aaagttgtat tagaaggcga caatcaaaaa caagcaagtt
    12241 ttctttcaga aagtcttgaa aaagtagatg cagaaaaagt gaatgatctg catttgatca
    12301 tgtctagtat ctcacgacca gaacatttga atatttttga aaaaggaatc gcaagcaaga
    12361 tcgatttctc ttatgctggt gcacaaagct tgcgtgtcgc ccaaatgatt gaagacggca
    12421 caatgaaatt aggtgatatc catacttatt tggaacttta tggacgctta ttcatcgatt
    12481 tgattccaaa tgttgtttta gtagctgcag ataaagcaga taaagacggc aacttgtaca
    12541 caggtttcaa tacggaagaa acaccaacaa tcatcgaagc tgcagctttc aaagatggta
    12601 tcgtgatcgt tcaagttaac gaagttgtcg attctttacc acgtgtagat atccctggtg
    12661 actgggtaga cgttgtcgtg aaagcagata aaccttatca attagaagct ttattcacac
    12721 gagatcctca aaacatcaca gaattgcaaa ttctaatggc aatgatggca atcaaaggaa
    12781 tctacgcaga acacggcgta caatctttga atcacggtat tggattcaat acagcagcta
    12841 tcgaattgtt actgccaact tatggtgaat cactagggtt aaaagggaaa atcgcgaaga
    12901 actgggtatt gaacccacat ccaacgatga ttccagccat cgaatcaggt tgggttgaaa
    12961 gcatccatag ttttggtggc gaagttggta tggaaaaata tattgctgct cgcccagatg
    13021 tcttttttgt cggtaaagac ggcacgatgc gcagtaaccg aacattatca caagctgcag
    13081 gacaatatgc catcgatatg tttatcggtt caaccttgca attagattac gaaggaaact
    13141 cttctaccgt aacaaaagga cgtttatctg gttttggcgg tgcgcctaac atgggacata
    13201 atcctggcgg tcgtcgtcat tctacaccag catggcaatc acttcgcgac aatgatgatc
    13261 cattagggaa aggccaaaaa ttagttgttc aaatggttga aacatatggt tcaaataaaa
    13321 aaccagtctt tgtcgaagaa ttagatgcac tagctgttca aaaacaagca ggcttagcca
    13381 atgcaatgca ccagtgatga tttatagcga agatactaca catatcgtga cagaagaagg
    13441 aattgcttat ttgtacaaag caaaaacaaa agaagaacga caagcagcaa ttgcagcaat
    13501 tggcggtgtt acacctcttg gaatgactag cacgaaagaa tcactagata gcttgcgtgc
    13561 agccggcatc gtgaaattac cagaagatct aggcatcaaa cgtagtgaag cgaaacgttc
    13621 attattagct gcacaaacca tcgatgattt gatcgaatgg tcagatggcc tgtatgaacc
    13681 accaatgaaa ttcagaactt ggtcataaaa ttggcgagaa aaaccttttg tcgccattta
    13741 cccagatgga agaagaaaga cgaataagca gaacgtgtat gctctgtttt acaaaaaggg
    13801 gagagatcca tggaacaatt agcttataaa tatccaacga aacagccgat caataagaaa
    13861 atccatgtag gagtggtcgg ttcaggagat ttggaaatct tgatgtttcc aacagaaaaa
    13921 acagaatcta ctgtaaaaat ttgtacagga agcgatggct tcggcgaagt atggaacaat
    13981 gtattaacga gattttttga tcgttatcca atttcagcag atatcgtgat caatgacttc
    14041 ggtgctacac caggagttgt gtacctacga ttgacgcaag caatggagga actttcagat
    14101 gaaaaatagt tttgtagaat taaacgccag agaacgagtg aacgctctac ttgacaatgg
    14161 acgtgaattg attgatccat tcgatcaaat catcgcgcca agtttaccag cacaaggaat
    14221 cgtccctgaa agtgatgacg ggatcgttgt cagccgtggc acgatcaatg gcaaacaagc
    14281 agtagtaatc gctatggaag gaaaattcca aggtggcggt atcggtgaag tttccggtgc
    14341 aaaaatcgtt gctgcacttg aacatgtgtt agaagaaaat aaaaaaggaa atgagatctt
    14401 tccagtcatt gtactagata caggtggtgt tcgtttgcaa gaagcaaact acggactgtt
    14461 atctatttca gaaatcggaa atgtaatcat tgctctaaaa caatatgtac cagtcatcgg
    14521 tttgattcca ggacgtgtag gatcatttgg cggtatgtcg attacttcag cattaatgag
    14581 ttatttaatc gcaacaaaaa aagcgagagt cggtttgaat ggaccagaag ttattgaaca
    14641 agaagcaggc gttcgagaat ttgattctag tgacaaagac ttgatttgga atacattagg
    14701 atctcgtcaa cgggtagaat caaaaatcat tgatgaatta gtgactgata gtgtagaagc
    14761 aatcaaagct gctgtcatcg cagcaatgga cgaacgaaaa gacacgcatc gcagtgaaag
    14821 ctcagcattt tatttatcat tacttgattc tttagatctt tcaaaaccaa tggccattga
    14881 cgattacaat gaagcaattg ctaaccatca agcaaaatca attgacttac cagaagtagc
    14941 agaaggaaat gaaccagctg cagcaagtgt tggttacgat tggtttgcgg cactaactgg
    15001 catgaaaaat ccaacttctt ctattagtac tgtgtattat ggtaaatcaa gtaaattcat
    15061 agaagaagcc atcgtgacat caatcgtacc tgatcctaaa aacccgatgt accgtgtacg
    15121 aaacggtgaa gttggtttag ttgaaggttt ccgcatggga caaattttgg atcacgttta
    15181 cgaagaagat aaagacaaaa aagtgaaacg gccaatcatc gttgtgatcg atgtaccaag
    15241 ccaagcatac ggctataacg aagaattgat cggtatccat gtggctttgg ctaatagtgc
    15301 tgctgcttat gcaaaactcc gtcaagctgg acatccagtt attggattga ttgcaggaaa
    15361 tgctatttca ggtgcatttt tagcacatgg attacaatca agccgcttga ttgctttaaa
    15421 caataaagaa attaccgtcc aagcgatgtc taaagaaagt gctgcacgtg tgacaaaacg
    15481 ttcggttgct gaaatcgaag cagctgctga aaaagttcca gctatcgctt acgatatcaa
    15541 taattataca aaactaggag cgatctatca tttcctagaa gatatcaccg accaagctgc
    15601 ttcagaacaa aatgtcagca aagtcatcga agcaatcaat gaagccattc aagatgtccg
    15661 caatacaaat gacacgatgc tgacaaatcg atacacaaac gaaacagcca aaacattcgg
    15721 acgtgtcgaa acaaataaag tccgtgccaa aatggacgaa gaatgggatg cataaaaaat
    15781 gattcaagca catgatattg tcctttttga taaacatgaa atagaagggt tcaccttgcc
    15841 tgaatgggtc gttctaactg aaaagatgtt cggaacagtt cgtcgtgcgt cgacggatca
    15901 cgcagaaata ctaccgattg gtttacgtgg acctgcccgc aatcagagat ggtcaacaga
    15961 aatctcaaaa catgccgtca aacaagtcat tcatccgtgg gacatcatcg aacaagaatc
    16021 gtatagacaa gagaaaatca tggattatcc tgtttatcag caatttcatg ctgctagaaa
    16081 catattatca ggatgtaaat ggggaatcgg cggcagctta ggatttgaat tatcgactgg
    16141 gattccggca gtaaaagaaa ccagtgattt tgatttgctg ctgtacgcaa attcaccgat
    16201 tgaattgcca attcaggtaa ttcaatcgca tcctgctttt tttgagcaat tcgataccca
    16261 agtagtgact cggcaaggcg gtttttcact aaaagagtat ttgagagagc cagagaaaaa
    16321 aattctattg aaaacagtcg aaggacctaa attaaccaaa gaactttggt aataaagaaa
    16381 aagagagaga aagagatgtt tgaaaacaaa aaaatcaaaa tcaacgtaag tgacttccag
    16441 aaagtatcag ctgtaacggc tgttatgatg caaacgatat tgagctttgc tttggcaaac
    16501 agccacagcg caacaaatac agcttttctt ggtacctttt acgtcatcgt taaatacaca
    16561 gcaccaatgt ttatttttgc aattgtttat aatatggtaa aaacaagtca gcatttgtct
    16621 tattgggaat ttttgaaaga aaagtttttt gaactagtcg ttccgtatct tctatggacg
    16681 acggcttatc tttggctatt tccagcagtc caacaacaaa ctccgtatac ggatactgca
    16741 agctttttac tgaaatatgt cacaggtgat ggagcgcctc atttatggta taccgttatg
    16801 atgctgcaga tccaattgtt catgccgttt tttgtttggc tcggttacaa agtatttgct
    16861 aataaaaaat atgtatggcc agtattgatt ggttcaacga ttttatatgt cgcatggtat
    16921 ctgttctatc aaacacaagt attgactggg ccttatcatg acagctggta cttattagat
    16981 cggtttgttg ctagtttcat gatttatggg gtagccgcat ttgtttatca cgaaaaagtc
    17041 tatcaatatt tggacagagt acgttatctt ttcttacctg ttgccttagt tatcgcgttc
    17101 ttttctgtcc gttcattgct cgcacatcca ggagacttga gctttgcgaa tgcaccttac
    17161 ttgaatacga tccaaagttt atacagttta gtcatcatct ttgctgtctt cataggcgct
    17221 tccaaaatga ttgtaaacga ttcgccaaaa ttgccattgt tcaaatggtt gtctgtttat
    17281 gcttatcgta cgtatttagc caatgtattt gttttccaag tactgttatt attgtttaaa
    17341 gatagttggc tgcagttacc ttcaggagtc atgattcttg tagcttatct aatgacggca
    17401 agttgtgcat ttgctttaag ctggttactt catatcattt gggtagctat caaaaaaggt
    17461 ttcagcaagt aatagtagga agaaggagtg agtgtcatga taaatgacga acgaaaaaaa
    17521 gcagtgactc agcaactcgc tgcgttggta gaggaagcat tgatcgcaga agtaacatta
    17581 agtccaaaac ctggattagt ggatgcactg gatgcgggtg cacattccga tatggactat
    17641 gctttatttc ttaagtctgc taagacgcta actccttttt ttgaagaaat ggctcaaata
    17701 gcatggcatc atgctattga tcaggagtta agagaaagaa ttgctgagat tgggcgaaaa
    17761 gcggaaaagg caatgctgat tgctacaaat ggcatcaata cccataaagg agcgatttgg
    17821 gcaatggggc tattgatcag tgtcattgca caaaaaatca gtatggaaca gcctttttct
    17881 ttatcgaaaa tacttgatga tgtcagcaag cttgctgctt ttcctgatac aaaatatcgt
    17941 cataaaaaaa ccactcatgg tcatagggtg aagcaaaaat atggcgtaaa tggtgcatat
    18001 gaagaagcga tattagggta tccgcatatc aggcttgcaa ttcaagcagc taaggagcta
    18061 gataatgatt catatgtaca gaaacaaatg catatgttgt tagttttgat gagttcgcta
    18121 gatgacacat gcgtattgca tcgcagtgat cagaaaacgt tagtggaaat gcaaaaactt
    18181 gctcatgctg ctagtcaaag tgctttacca aatcgtccat ttacagcact gttgcacttt
    18241 tgtcaggaaa accaaatctc tcctggagga agcgcagatc tcttgtctgc aagcttgttc
    18301 atgctgaaga tagaggaatt atggactgcc gacacataca tttgtccgat gttactcaat
    18361 gactaaataa gacaaaattg ctaaaaaaac agtttatgca tctggttatt gactcttcct
    18421 tttagcaagg ctatcataaa aatagttttt tgtaataaaa gataacgagg aagacaatga
    18481 aaaaaatcaa ttatttagca atcattttgt tagtgggcct atgtttgttt gctctgccga
    18541 cccaaggatt cgctgtcgcg ggtggtcatg gtggaggtac atctagcggt cgaagttcgg
    18601 gcagaggttc atttggtggt cgttcatatg ggggcagtta ttttggcagt cgttcttacg
    18661 gcagagattc ttatgggtat tatggtccag gtacaggtcc ttctagttat gagcaaacgg
    18721 gatttcttgc attagctgtt ttgtcagtag gaggggtttc tgctttttct atcgtcaaga
    18781 ataaaagaca aaagaaaagg ctgaaagcgg agatattgtc ccgcatgtca ggaacggcta
    18841 aagaaaagaa agcacagttt ctggaaatcc aaaagatatt catgaagatc caatccgctt
    18901 gggaagaaga aactcctgaa aaagccagaa gctgttatac agacaagctg tttgccgaac
    18961 atcagaaagt tctgcaaaaa aacaaagcag acggtgtaag aaatcatact aaaaaaataa
    19021 ctattcagga agtaggaaat tatcgacaga tccacgaaaa tagttttgcc atccgaattg
    19081 atttcagatg ctgtgattat tcagtcgatc gaaaagatgg gcgattgatc tcaggaagta
    19141 agacacaacg acagtatttt tctcagatat ggtattttga tttttctgag aaagaaaaaa
    19201 gatggcaagc cgattttatt cagccgatta tgctggattg acaggaaata tttatgaacg
    19261 gagttgtgac aaaagccttg tcgcagctcc tttttctgaa taaacggtgt gccagagata
    19321 gcctatcggc aataaggcac gattttgtaa aatatgggaa gcgatttttc aaaatcgctt
    19381 cttatcgctc aaggctgaac atctctgtca caacctctcc actaaatggt gtttaaaagc
    19441 ttgcatctgc gataataaga acaaccaaac gaaaaatagg aagcactatt ttagtttagt
    19501 tgttcttatt acttgatgca ggacagcttt ttcacaacct cttttttgta tagatgggca
    19561 aaatttttgt aataataggc gtatgtcttt ttcgttgagg agatgaaaaa gcatatggct
    19621 tattttttgt ttgctttgct tactttcttt ccacttcaag tggcagaaat atctactttt
    19681 tattatgtaa gcggaaccat atacttgaaa tcagaaggag atcatttcta tgaaaacaag
    19741 aacaattgaa atacttcaca gaatcatgac agcccaatat ccagtaaaag caaaacatct
    19801 agcaagtgag ttcaatgtca gtcagcggac gatccgtcag gaagttcttg aagcgaatat
    19861 ctggttgagc agtaaaaagc ttccggagat ccgtacaatt cgcaacaaag gttttttgtt
    19921 gaagctggaa aaggaaaagc aagctcgatt agaaactgaa ataaaagatg tgaaagacgg
    19981 ctttttgaat cggcgcgaac gtatttttga tctagtttta gccgttgctt acagccgaat
    20041 cccgatccat ctaaacaaaa aagaagaaga atttcaaatc tctaaaagta cattagatga
    20101 agatatgaga cggttacgag caacactggt cagttatggg atagagatcg tcagttatgg
    20161 aaagcaagga ctggtttata aaggttcaga acgatctatc cgtacgatga tctatgattt
    20221 tatcaatcag aatctgggaa tgaccgactt ctttatgaat caagatgcac aattaacacc
    20281 ggctcaaaaa atctttctcc attattttcc tttggtggaa atcaaaaaaa tacaggagat
    20341 ctattccaat aagttgttga aacaagaaga tgatatttat aaaaaacaaa tcctgctttt
    20401 tacattgatc tggatccagc gaatcaggaa acatgaattt atctctgcca ttaattggaa
    20461 aaatacagaa ataaaagaca gtagcttttc tgcatttatt gaccacatga tcgaggaatt
    20521 tcaattggac aatgtcccgc aagtagaaag aaattatctt cgtttcacta ttgagacgtt
    20581 caatgctaga gatatctcca attcaatcga gtgggtacaa gctcaattac taacgatcca
    20641 attgatccaa tttgtagaga acgagacaca cgtacctttc catctaaagg aagaagcttt
    20701 attcgaaaat ctctataagc acatggctgc actgattgta agaatcaaga atcatatcca
    20761 agtcatgaat ccattgaaag aaaacatccg aacaaattat ttcccaatct accgcgcagt
    20821 cactcatttt gttcctacga tcgaagaagt aattggtggc aagatactgg aggacgagat
    20881 agcttttctt gtcatccact tttcgacgat cgccagtgta atcaagcgag acttgaatta
    20941 tgtttataaa tcagtcgttg tctgtaacca tgggatggct actggaaatc tgttagcaga
    21001 gaatctgaaa gaaaagtttc ctcagatcga gattactgca gttttaagtt caaaagaaat
    21061 cgaattagta gataaattgg atgtcaatct ggttttcagc acctttcaat tgaattatcg
    21121 aaataagccg cttttagttg tcgatccgat tttaactgag acgaatatct tggttataga
    21181 agactttttg aaaagaaatg aagaactaca gcggttagag cctaacagtc atgaatcgac
    21241 ggagttattc actcaaataa tagatgtcat gaaagaaagt ggtggccgag tagatcgaat
    21301 catctatggc aagttagaaa aattattcga aacaaacaat ttagaaatca acaaaaggga
    21361 gatccagcct atgttaaaag atattttgac ggacagcaat atcatgatca aagaaaaagc
    21421 cactacttgg gaggaatcga ttgaactagc tgctagacca ttggttaaag aaaacattgt
    21481 cgaagagcgc tatgtcgaag cgatgattcg tgcagtgaat gattacggac cgtatatcgt
    21541 gattggcaaa cacatggcac tagcccatgc ccgaccagaa gatggggtca ataaattagg
    21601 agtcagcgta gctacgattg agcaaccaat cgatttcggt aatcctgaaa tggatccagt
    21661 aaagattatt ttttgtttgg cagcagtaga ctcctactcg catctgaaca tcatgaaaga
    21721 actaattgaa ttgatcaaca acgaagagaa gttggatcga ttgattgaat gcacaaatat
    21781 cgaagatttc aaacaactgc ttttttcagt agttgagaaa taataaatga tacgggggag
    21841 aacaaagatg aacaaattga acattttatt cgtatgcggt gcaggtttag gaagtagttt
    21901 tgcagcacag atgtctgctg aggatgtttt gaacaaatta ggagtagaag ccaaactgga
    21961 ccattgtgat atttcttccg cagtttccat gaaaccagat gtgatcatca cagcagaaaa
    22021 ttttcgttcg cagttcgaaa agttcgcagt tgatcctaaa acggcgatga tctatttgaa
    22081 aaatattgtt tcaaaaaatg aaattgaaga aaaaatcacc ccagttctgc aagataaggg
    22141 agttatctaa atacaaaaag aaaagagggt aaaa
//
LOCUS       DADVXE010000044        21813 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.045, whole genome shotgun sequence.
ACCESSION   DADVXE010000044 DADVXE010000000
VERSION     DADVXE010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.045"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(530..2026)
                     /gene="lysS"
                     /locus_tag="KB913_001825"
     CDS             complement(530..2026)
                     /gene="lysS"
                     /locus_tag="KB913_001825"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBB6820183.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="KB913_001826"
     CDS             complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="KB913_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBB6820184.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="KB913_001827"
     CDS             complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="KB913_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBB6820185.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="KB913_001828"
     CDS             complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="KB913_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBB6820186.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="KB913_001829"
     CDS             complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="KB913_001829"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBB6820187.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="KB913_001830"
     CDS             complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="KB913_001830"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBB6820188.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8557..9027)
                     /locus_tag="KB913_001831"
     CDS             complement(8557..9027)
                     /locus_tag="KB913_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBB6820189.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9073..9498)
                     /locus_tag="KB913_001832"
     CDS             complement(9073..9498)
                     /locus_tag="KB913_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBB6820190.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9565..9834)
                     /locus_tag="KB913_001833"
     CDS             complement(9565..9834)
                     /locus_tag="KB913_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBB6820191.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9845..11440)
                     /locus_tag="KB913_001834"
     CDS             complement(9845..11440)
                     /locus_tag="KB913_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6820192.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="KB913_001835"
     CDS             complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="KB913_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBB6820193.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14993..15553)
                     /locus_tag="KB913_001836"
     CDS             complement(14993..15553)
                     /locus_tag="KB913_001836"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBB6820194.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15906..16880
                     /locus_tag="KB913_001837"
     CDS             15906..16880
                     /locus_tag="KB913_001837"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBB6820195.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17050..18450
                     /locus_tag="KB913_001838"
     CDS             17050..18450
                     /locus_tag="KB913_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBB6820196.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18528..19250)
                     /locus_tag="KB913_001839"
     CDS             complement(18528..19250)
                     /locus_tag="KB913_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6820197.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19329..19835)
                     /locus_tag="KB913_001840"
     CDS             complement(19329..19835)
                     /locus_tag="KB913_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBB6820198.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19958..21757
                     /locus_tag="KB913_001841"
     CDS             19958..21757
                     /locus_tag="KB913_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBB6820199.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
BASE COUNT         6053 a         4752 c         3911 g         7097 t
ORIGIN      
        1 gagtgtttcc cgattcattt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcggc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataactt ttttgttatg tttttgaata aatattttct tctgtctttt
      301 ggacaagtaa taatatacca actaaattta gcttggtcaa cgaatttttt gtattttttc
      361 aagttttttt caataaacga ttattcataa cttttctttc tttatcgttc gttttcgtct
      421 tctttaatgt ctagaatagt cggcattagc ttttgaactt tcgttattat ttattccttt
      481 ctacacagca aaagctgcct aaggaattcc ttagacagct tttattcgat tatctcattg
      541 ttgggaatag caaaacatcc cgaattgatt gtgcatcagt tagcaacatt actaatctgt
      601 cgatcccgat gcctagacca ccagttggcg gcataccgta ttctaaggct tccaagaagt
      661 cttcgtctac accgtgagct tcgtcatttc ctagttcacg ttctttttct tgcgcttcga
      721 atctttctct ttgatcaatt ggatcgttca gttctgtaaa ggcattagca aattcgcgcc
      781 ccactatgaa tagttcgaat cgatctgtga atcgaggatc ttctggattt ttcttcgcta
      841 aaggcgaaac ttcgactgga tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa
      901 caaatgtttc aaagaattca ttgataacat gtccgacacc catagcttcg gttacttcta
      961 cattgtgttt ttcggctaaa gctaatgctt cttccaatgt catttcttgc cagaagtcta
     1021 caccagtttg ttctttgatt gcatctacca tatggatgcg tttaaagtca ctttctaagt
     1081 cgacagcttg tccatcatat gtgatttttg ctgttcctag tactttttca gctgcgttac
     1141 ggataatacc ttctgtcaga ttcattacat cattgaaatc agtatatgct gtgtatgctt
     1201 ctaacatcgt aaattctgga ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc
     1261 cgatttcata aactttttcc attccgccaa caattagtcg ttttaaatga agttctagcg
     1321 caatacgcaa atataaatca atgtccagtg cattatgatg cgtgataaat gggcgtgcgg
     1381 cagctccacc tgcctcattg tgcaatactg gtgtttctac ttcaatatag ccattgccat
     1441 ctaaatagcg acggatttcg ctgataattt ggcttcgttt cataaatcgg tcaaagcttt
     1501 cgcgattact gattaaatcc aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc
     1561 catggtattt atctggcagt ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt
     1621 tgatagaaac ttcgcctgtg tctgttttca tgatttgtcc agttacacca aagaaatctc
     1681 caaggtctgc atgtttgaat acttcatagg cctcatcacc tacttggtct tttcttacat
     1741 aaatttgaat ttggccttca cgatcttgta gatgcgcaaa tccagctttc ccttttcctc
     1801 ggcgagtcat catacgacca gctacactag cggtcaatcc catttctgct agttcttctt
     1861 ttgttcttgg atcaaatagt tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt
     1921 ttccaaatgg atcgattcca tcttcacgca attgttccat tttttgacga cgtacaagca
     1981 tttgatcatt taaatcttct acttgatgtt gttgttcctg tgtcacaaaa gttcctccat
     2041 tctcatgtta atctctttcc tataatgcca atgaaacaca aaaaaagcaa gccgaacttg
     2101 gaatttcggc ttgaaaattc acgaaaaact tagaaatcac aacgtttgtt tcaatagtac
     2161 tttttccgct ttttctacaa attgatccag caggtcattg atttcttgct gtttttctgt
     2221 ctgattgatt gctactttca ctttcgctgc tcgaggaatc ccttttaaat aataagccgc
     2281 atgtgttctg aattctctac aagctacttt ttctcctttg agatctgcta agcgttgtaa
     2341 atgaagttta gctgtagcaa ttttttcggc tggtgttggt tcaggaatca gttcccctgt
     2401 ttcgagataa tgctgtgtgc ggtgaatcat ccatggattg cccagcgctg cacgaccaat
     2461 catcacaccg tctgcaccga catagtcaag catccatttt gcatcttctg gcgttttgac
     2521 atccccgttc cccataaatg gaatcgtcaa atgttttttc acttctttca atacttccca
     2581 gtccgctttt ccttcataca tctgaacccg tgtacgtcca tgcatagcga tggcacttgc
     2641 tccagctgat tgtgctgcta atgcattttc tacagcaaag acgtgctctt catcccaacc
     2701 aatacgcatc ttgattgtta ctgggatatt tactgctgaa gaaacagctt ggaccatttc
     2761 gtatactttc tcaggatcta aaagccattt tgctcctgct tctgctttga ttactttatt
     2821 tactggacag cccatattga tatctattat atcggcagct gtgttttctt cgacaaattg
     2881 agcagcttca actagactat ctttatttcc gccaaatatc tgtaaactta atggatgttc
     2941 tgtttcttca atgtggagca tctctaaagt ttttttgttt ctgaaatgaa taccttggtc
     3001 actgatcatt tcacatacga ctaagcccgc accaaattct ttgacagtga ctcgaaatgc
     3061 tgaatttgtt attccagcca tcggtgcaac aacgacacga ttagggattt ccacattgcc
     3121 aattttccat gtgtgttcca cttaaatccc tcctaaggct tctttcttca atccatctaa
     3181 ttcttcttcg ctatacttgt atttgttatt acagaaagaa caaaccgctt ctgcaccgtg
     3241 atcttcgtct atcattgctt ggatttcttc tgcacctaac gcgataattg cttctgcaaa
     3301 tttttctttt gaacagtcac atttgaattg aacaggcatt ttttccaaaa tgttcaattc
     3361 ttctgtacca agcaatcctt tcaatatttc ttctggtgtc tgtccttcat ctaagagggt
     3421 agagattctt ggtgtcgttt ttaattgttc ttcgatcttg ctgattgttt cttcatcggc
     3481 acctggcatg atttggatca tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac
     3541 caatacactc agtccaacag ctgaagggat ttgttctgag atagcaagat agtaagtaaa
     3601 atcttcagcg atttctccag aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc
     3661 taagtctttt gtgacagtaa acattccttg tgttccaact gctccccgca catcgatttt
     3721 accttcacta tttagaggaa gactgagatg cggatttttg atgtaacctt tcacatctcc
     3781 ctttccattt gcatctacta caattcctgt tgctggacca tcgccttgga ttcgaacagt
     3841 tagtttgtct tctcctttga gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc
     3901 caaagcagct gaggaggtgt gccaagtatc atgacgtctt tgtgcctccg ctacggtatt
     3961 tgttgcttga acggcgtatg ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata
     4021 atctttcatt tgttatgtac tcctttttcc gtttttaaac tcatagtgaa tcatactagc
     4081 aactactgct tttttcaact ttggaatgct tcttttaaaa ataattcaga atcatctaga
     4141 aaacaggaca tcaccctatt tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg
     4201 ttccggtttt cgggagtcat atcagatcaa ttgacctata tttttttatt tgtattgatc
     4261 gtctgaatga ttatcttctg attgttgaga atctgaatca tgttctgctt tattttcctc
     4321 attcagttca tgttttgctt cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc
     4381 tttttcttcc aaagcacgtt ttgcttcttc aaaagttttc gcttcttttt cgcttggata
     4441 atcatttgac tcagtacctt caggcatcac accgtgttca aacaatgact tgattgcttt
     4501 ggcatccaat gtttcgaatt ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg
     4561 agcttcgatg atttctcgag ctttatcatg agcttccatc aagatttttc gtacttcttg
     4621 atcaatctcg aaagcgactt gttccgagta agcttttgtt tgaccatagt cgcggccaac
     4681 aaacacttga tggtttcctt catattgaac aggacctaaa cgatcactca ttccatattc
     4741 tgttaccatg cttcgtgcta gagctgtcgc ttgctcaaag tcattggaag caccagttga
     4801 ttggacattg aagatgattt cttcagctgt acgtccacca agtaagccta cgatttgttc
     4861 aaacatatct tctttcgtca tcaagaactg atcttctttt ggtaaagcga tcatatatcc
     4921 gccggcgcgt ccgcgaggga tgatcgttac tttgtggacg acccgagcgc gactcaatac
     4981 taatccgaca atcgtatgac cagcttcgtg ataagcaacc atttcgcgtt cttttttgct
     5041 gattacgcga tcttttttag ctggacctgc aatcacgcga tcttccgctt catcgatatc
     5101 agaagcatcg attttctttt tatttcttct agcagctact aacgctgctt cattcaagac
     5161 attttctaaa tctgctccgg caaaacctgg tgtctgttga gccacaactt tcaagtcaac
     5221 gtcatctgcc atcggtttat tccgtgcatg gactcgcaag attgcttcac gaccttttac
     5281 atctggacgt ccaactaaaa tctggcggtc aaaacggcct ggacgtagta acgctgggtc
     5341 tagtacatca gaacggttgg ttgcagcaat gacgattact ccttcatttc cgtcgaagcc
     5401 atccatttct acaagcaatt ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat
     5461 accggcacca cgttgacgac ctaccgcatc aatttcatca atgaaaatga tagctggtgc
     5521 gtttttcttc gctgtttcaa acaaatcacg aacacgactt gctccaacac cgacaaacat
     5581 ttctacgaaa tcagaacccg agatcgagta aaacggtact ccagcttctc cggcaacagc
     5641 ttttgctaat aaggttttac ctgttcctgg aggtccttct aaaagtacac ctgccgggat
     5701 acgggcacct aattcaacaa atcggcgagg atctttcaga aattcaacaa cttcaactag
     5761 ttcttgtttt tcttcttccg cacccgctac atcagaaaaa cgtacgcgat tagctttttt
     5821 gtctgcttct ttggcttttg atttaccaaa gttcatgaca cggccgccac cgccaccgcc
     5881 gccgccttgt tgtcccatca tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa
     5941 gctaagcaat agggaaaccc atataccgct gcttgattct tcttttactg ttgtagcaac
     6001 tttgttttct tttgccagtt ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat
     6061 tgttgtgaaa tgggtagtag tcgtatctgt tgaacctaag atagctaacc caccgctgtt
     6121 agcgacggtc tgctgttctt tgtattcacc agtgatctta tatacaccat ttgcaggctg
     6181 cacttcaaat tctttgatct tgcctgcttg tagttgttct gtgaattttg agtactcgat
     6241 atctgacgat cgctggccgt tattaccaaa aatgaaataa acgaccatta ccatcgctaa
     6301 gattacgagg acataataca aggcattttt catcatgccg ttgttctttt tgttcatagt
     6361 tgccctccct aagcgtcaat ttaatttaac agttttttat caatcctgac cattctattg
     6421 taccataatt taattgagat acagcattaa tttgattgat aaacactagg tttcaataca
     6481 ccgatgtacg gaaggttacg atatgcttct gcataatcca agccataacc gaccacaaat
     6541 tcatttggta cgttgaagcc aacataatct gcttcgatat ttactactct tccttcaggt
     6601 ttgtcaagta gtgtaacaat tttgactgat tttgctttgc ggtatttgaa aagatccact
     6661 aaataagcaa gtgttcttcc gctgtcaatg atatcttcaa cgatcaacag atcgcgacct
     6721 tctacattcg tatctaagtc tttgacgatt tttacttccc ctgacgagac tgttgcattc
     6781 ccgtagcttg aaacatccat gaaatccaat tccaaatacg tatcgataga acgaacgata
     6841 tctgccatga atggtaccgc tccttttaag acacctacta ctaggggatt ggtgttttgg
     6901 taaatttctg ttaactcttt gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag
     6961 atcaaaattc tctcaatatc cttttccaac atcaggttct ccttccaatt gcttcttttt
     7021 gatatttgta aagaagtatg tagtgtattt tatcagtttc ttcacgaata ctcaaatatg
     7081 aaaaggcaaa aggtatcaag ctatatatat ttcttttggc atctgtaatg atccaagcat
     7141 gctgcctttg tgaattaggt actttctgat cgataaaata tctagatact ttttttgtga
     7201 gattctctgt taatttaatg cggtctcctg cttttctttt ttcgacatac agttgcacat
     7261 cagcaggaat ccaaatgtca tgagaaaata gagaccatga atctgttgct ttgatgtccc
     7321 ctgcattttc aggtttgacc agaccaatcc attctgtttc attcaaatat attccttgtt
     7381 ctggaatcag caacaagcgc tggtcttctg tctggctagt tgcttgtttt tcttttttag
     7441 agagtacaac aaaatgatac tctcttttca gtatccaatt attgccaata ctgagttgcc
     7501 attggctttt tttctgttgc cactggtcta aaatcgactc catttgttgt tctttcaaaa
     7561 taattcctgt ttttgagaat gctttgtcga aaaaggagta aaaaaaatag tatcgttcag
     7621 catctgtcat ttcttcaatc atttctgcag aaaatcgaaa ttgttcctcc cactgttcga
     7681 cttccttttc gatcaactgt cccatatatt tttgaatgac ttggtctgcc cattggatct
     7741 gttgcgaaaa ttgctggaaa tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa
     7801 ctaccaaatg acgaagccga tttctctgga tatctaacaa ttggtttgtc tgatcctcaa
     7861 agtaaacaag ctgcgattcc gctgcataag tatataggtc ttctttgcta aaactcagca
     7921 acggacgaat cagtctgccc gtagcaaatg gttgtacttc tttgattcca gaaaaagtat
     7981 ttaactgtcc cccacgaacg attttcatta acaccgtctc gatttgatca tctccgtgat
     8041 gagcagtcat caacgtgtca tattgtcctt cttccatcac gcgagtgaat tcttgataac
     8101 gaaagttacg agcttctgtt tctatggcgg atttggctgg atcttcccaa atacttacat
     8161 ataaagggag attcttctct tcacaatatg agcgaagata ggcagcttct tctgctgatt
     8221 cttctcttaa ttggtgattg atgtggacga tacctaaaga aaaaccgatt tggcgttgca
     8281 cttgtaaaag taaatggagc aaaaccatcg aatcaacacc acctgatacc gctgctaaaa
     8341 ttctcgatcc ttgttgccag aatccttgtt cattcccgtg ccgaataaat gactgctgta
     8401 atagcggtgc ttttttcccg cctttttcaa cgttcatcct ttccacaccc tttcttccta
     8461 aaaaaaagag agcgggaaaa cgtctaaaac gacaattaac ctgccctctg ttgatactat
     8521 gacccaaata gtcgcactat cattatttgc ggctttttag ctgcgacgtc cgccacggcc
     8581 accgcgcttt ccttctgtgt ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa
     8641 aaatgaactc atcaatgaat cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa
     8701 agattttttc tgtgctggac gatttcggtt gtcacgggga tctttttgtt gatatttttt
     8761 aggacggctt tcttctccag attcagcagg ttgttcctgc gctttccgga tagatagtcc
     8821 gatttttcca tcatcattta ctgaaataac tttaactgtt acttcatctc ctacacttaa
     8881 aacatcatgg atgtctttta catagccatt tgacacttcg ctaatatgaa ctagacccgt
     8941 ttttccagca cctagatcaa taaacgcacc aaaatttgtg attcctgata cttttccttg
     9001 cagttttgct cctacctcga ttgacataaa aaaaatgttc ctcctaatta tttccctttt
     9061 ttatattcct gcttattttg cagttgtaga actagttgat tgatctgttt catttgtcga
     9121 gctgtctgta tttgattcta atataggata aactttttca ccgtcttttg agtaaaagaa
     9181 tttgcttctg gcaagtttag ctacatactc atcatctttc agcaatgaaa catcttggtg
     9241 cagctgatca acgtctgcgt tgacttcttt catttcagta tttgcttcga ctctcaattc
     9301 gttcaattga tgcatccttt gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat
     9361 gaccaaagca ccaacaaaaa ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg
     9421 ttgttgctga aattcagcat actttttctt tgcatattcc gtatctagcg cagcgatttt
     9481 attgcttttt ttcgtcactt ggattcgctc caatcttttt gattgtcttt ttcattatac
     9541 caatatcgtg aaagcttgtc taatctattt ctctagtgtt tctgtgcgat tttcagaaat
     9601 aatttcgtac attttttgtg catcttcttt tttggttgat tcatgtaatt ccgtaatttt
     9661 cacttccaac gttttgttgc caaactggac tttcaaaata tcgcctactt tgacatcact
     9721 ggaagatttc gccaatttac cgttgatttg aattcttcct ttatcagcta cttcttttgc
     9781 tactgatcgt cttttgatga ttcgggaaat ttttaaaaat ttatctaatc gcatatctta
     9841 ttcctcactt tttaattttt ttatttaatc gcaggatttt cttaccaaaa ggcaacatta
     9901 gccattctcg tactgtaaac agacgaagac gaatcactgc ataaatgaac acagaagccc
     9961 cgatcccaac tcctatcacg ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa
    10021 atactatatt caatacacca taatacagca gcagtactac tgtcatacaa agaaggctga
    10081 acatcaactt ccgtccaaaa tgccgttctt tccaaaaagc atttagctct tttgtttcaa
    10141 ttcgaacaaa ataccaaagc gtcacaccta atcctaaaag ggtagacagg cttgcacctg
    10201 ctgttcctaa taaaccggtc agaaaagaag tagtcaatcc ttttaccaat agtccccatc
    10261 ctgcgccttt taaagaaggg cgaaacgagt tcttgctttg agcaatactt tgataagctt
    10321 ggatgactgc agtgaaagca atggaaaaaa caaataatac aagcgctgca tttcccgcat
    10381 aatctttaaa caacgcataa ttgatataag ggagcagcaa ggctaatccc aaagacgcag
    10441 ctaatgctaa agcggtcgtc aatctaagat agattttggc tgtctgtaaa aactgacgat
    10501 agatccggtt ggtcaaatga cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg
    10561 caatcactaa acctaattgt actaaaggct gacctcgatc atagacccct tttgctatct
    10621 tcgcaccgta ttctgacagt ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga
    10681 tcagctggaa aaagataagc aatccactat aaatcgaaac cagtccgcct tctaccagaa
    10741 aacgccggat caagggcttt gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg
    10801 ctcctccatg aatcttttgt tcatagtagt gaaggatccc atatgcgcat aaaccgccaa
    10861 aaacagctcc actcattgct gccgtccctg tttggtacac cgtccatcca agctttctaa
    10921 aagcaaacgc actacagaca atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa
    10981 cagcagttgg ttccatcaag aatcttcctt ggaaattccc tcgataaaaa gatagaccag
    11041 gcatcagcaa aaaggtaaag gaaactactt ggatcagcgg tttcaattgt atgtctccca
    11101 tcatccaagc aatccagctg ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc
    11161 aaaatactaa gggataaaga ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt
    11221 ctgcaacgta ctttgatatg aactgcggaa gaccggataa agctaaagtc attgctatcc
    11281 cataaattgg ataaacttgc tgataaacat aaaaaccttc gtcgccgact aagttttgga
    11341 ggggaattcg gtaaagggca cttaatactt ttgctatgaa agaagcaatc gtcaatacaa
    11401 atgctccttg catgacgcgc cgcatttctt tatgatccaa atcattgctc cttcctacgc
    11461 tgacagatat ttttgctcac gcaacgcttt gacaaacttt tggatttcct gaagccatac
    11521 tgcttcttcc atttggttgg ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc
    11581 tagactggct tttagttttg tcgctgtcag tgcttcgaat aactgttcca cactatagcg
    11641 ttttgttcca actttactta gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc
    11701 taggagcgct cgatcgccat ccattttgat ctgcccaatt gtcaagagat gtgctacttc
    11761 ttctggatat tctccaaaac ggtcgagcag atcatcttct agttcatcta gcatttcttg
    11821 cgaatcaagt tcacgaattc gtttatagat ctcgattttc tgccgttgat ctgccacgta
    11881 tgtttcaggt agatacgcat cgacaccgag gtcgatctca acagtggtct tctccacttg
    11941 actattcttt ccttgtttac gagaaacagc ttcgcttagc atttgagaat acatatcgaa
    12001 accgactgca tcaataaatc catgctgctg agcacctaag agattacctg caccgcgaat
    12061 ggaaagatcc cgcatcgcaa tcttgaatcc agatcccagt tctgtaaaat ctttgattgc
    12121 ctgaagacgt ttttcactga cttcgttaag gatcttctgc tgctcataca taaagtaagc
    12181 atatgcgaca cggctgcttc ttcctacccg ccctcgcaat tggtataacg tggataatcc
    12241 catataatca gcgttctcaa cgaacaacgt atttgcgttc gggatatcta ctcctgtttc
    12301 aatgatggtt gtagtgacaa gaacatcata ttgaccttca ataaattcaa aaagcgtatt
    12361 ttctaattgc gcctctgtca tttgcccatg agcataaccg atccgtgctt ccggaacgag
    12421 ttcttggatt tcttctactt tttgttcgat cgtttctacc cgattatata aatagaatac
    12481 ttgtccacct cgtcccattt ctcgatggat tgcttcgcga atagccccag gatttttttc
    12541 cataacatac gtttggatcg gataacgatt cgcaggcggt gtttcgatta ctgaaagatc
    12601 ccgcacgcct aacatcgaca tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa
    12661 aacatccact tgtgcacgta actgtttcaa tcgttcctta tgttttacac caaaacgttg
    12721 ttcttcgtca atgatcagta gacccaaatc gctaaattca atatcttttg acaaaattcg
    12781 gtgggttcct acaacaatat caacttgacc tgtacgcagt tgttcgatgg tttctttttg
    12841 ttgctttctt gttctgaaac gacttaatag cccgatattt acggggaaac cttcaaatct
    12901 ttccagcatc gtttcatagt gctgctgtgc caagatcgtt gttggaacta aaaaggctac
    12961 ttgtttgctt tcctttatcg ctttaaaggc cgctcgaagc gctacttctg ttttcccata
    13021 accaacatca cctacgagta gtcgatccat tggtttttct ttttccatat cccgtttgat
    13081 ctccgctgca cttctcaact ggtcatcagt ttcagagtag gggaaggcat tttcgaattc
    13141 tttttggtag gcgtcatcag gtccaaaagc atatcctttt tctgactctc ttgcggcata
    13201 taatttgatt agatcgtcag cgatatcctc gatttttgaa gagacttttc gcttggtttt
    13261 cgtccattca cttccgccta gcttattgat gcgaggcgct ttggcttcag aggcgacata
    13321 tttttggatc agattcagtt gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa
    13381 aatagtcata tagtcttggt gaacgccatc tacttctagc gtttccatcc caatgtattt
    13441 cccgatacca tgattggcat ggacaacgta atctcctgct tttaactcat tatagctttt
    13501 caatcgctct gcgtttgtta ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa
    13561 aatttctttt tctgtgatag ctactatttt ttcttgagga agttcaaaac cagcctgcaa
    13621 agctccttca actaattgta cctgtcctct gatcaatgca tttttttctg tttctactac
    13681 taatatgtct tcatctcgaa gcatttgttc tgctttgcgt attctgtcct ttgtcggaat
    13741 aaagatcaca acagtctgtt tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg
    13801 catttgtccg aagaactgtt gcatcgtccg atattgaaaa ttatggattg cttggaaacg
    13861 aagatttccc atcccttttt ggaagagtga gaaaaaggtt gtggtgaact tttccttctg
    13921 cacgattttt tgtatatctg ctgaaaatgt ctgctcagaa aacacccgca attcgctgat
    13981 tttttgagtc tgccattctg ccgcttccct ttcgatttcc cgatttgttt ccatgattcg
    14041 ctgataatca tcaacgacta gtaaactatt tgaagggaaa taatccaaga tcgtcacaga
    14101 ttcttggtaa agaagatctg agtagaattt tgcttcttct gtcgggacac ctgcttgcca
    14161 gcttgaagtc agctgaccga agtaatcttg caaaaactcg cggtctgctt cttctgtggt
    14221 cgcagcaagc cgtttttcta gcattttttg catttgctct attccatgtt ctagatcctc
    14281 tggtccgtag acttgttcac tcgttgggga aacccagatt tcttccgttt tttcgattga
    14341 gcgttgtgtt tctgcttcaa aataccgcat agaatctatc tctacatcaa atagttctac
    14401 acgaacagga taggttgtcg ttaacgggta aatatcgata atgcttcctc gaatactgaa
    14461 ttctcccggt tttgcgacca tctcttctcg tacatagccc atcaaagtca attggcgagg
    14521 aagattttcc acgtctatct catcaccaat atgccaattc aattgcgcct gtagccaagt
    14581 tttcttattc ggcagtcgtt tgtgcaaaga tgcgactggc aacaaataga tacctgcttt
    14641 tttttcttga agtgcgttaa gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa
    14701 ggccatttca gcagaaagca cttcatccac tggaaataaa tggatctgat cttgcggaat
    14761 cacatgttgc agatcttctg ctaactgatt cgcataatac aaatttggca tcagaataat
    14821 catgttttta tttgttttct taaacgctcg agcaaataga agtgttttcg ctgagcccgc
    14881 taatcctgtg attagttgtc taggcatttt ttcttctaaa ttgctgaccc attcttttac
    14941 ttgcggatct tttccgacta attgaataat atccattcct tttcctcctt cctcaattga
    15001 atcgattcat cgcatccacg aacgaatgcc cttctatgag atattcgact gctttaacag
    15061 attgacacat gctttcttct atcaaaggct gattttcttt gctgaaagga ctaagcacat
    15121 gctggactac tgtttttttc ccttctggcc tgccgattcc caccttgatt cgatcaaaga
    15181 cattcgtatt caaatgggaa ataatacttt tgataccgtt atgcccgccg gcacttccct
    15241 tttgacggag ccggattttt cccactgcca gatccaaatc atcgtagatt acgactaatt
    15301 cctctggata aatcccaaaa taagtcatta gtgggccgac tgcacgacca gattcattca
    15361 tgaatgtttg tggtttgact aaaaggatct tttctccatt atgaaaaaat tcggcaactt
    15421 ctgcttcgaa cggatttttt ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga
    15481 ccataaagcc gatattgtgt tttgtatatt ggtatttggt acctgggttt cctaacccga
    15541 cgatcatttt catttttgtt ttccacctaa ttctaaaaag cagcacaaaa ggctggactg
    15601 ctaattagcg gtccagtcca tcgagctttt ttctttttta cacttgtcaa tgcatagtat
    15661 aacacaaaac aaggcgtttc ggctaaaaga gaatcgttaa taaatgataa agaaattaaa
    15721 aatttcttca aagtttaatg aaataattga tatataaaaa tagtgaaata acgcacatgt
    15781 aagcttttac atataataca accttgttat ctgttatatt ttatagccaa atagcgtgac
    15841 atggggcttg agaaatgtta gcataagcat gggaaaaaac aaatcaatgg aaggattgat
    15901 actaaatgac tgcagctgca gaaaaaaaag atcatcaaaa agttattctt gttggagacg
    15961 gcgccgtagg ttctagctat gcctttgctc tagttactca aaatatcgct caagaagtag
    16021 gtattgtgga tatcaatact gctaaaactg aaggagacgc aattgacttg tctcacgctt
    16081 tggcatttac ttcacctaaa aaaatctatt ctgctactta cgcagacgca catgatgctg
    16141 acttagttgt tattacagct ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag
    16201 taaacaaaaa cctaaaaatc aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta
    16261 acggtatctt tttagttgcc gctaacccag tagatatttt gacttactca acttggaaat
    16321 tctcaggttt ccctaaagaa cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt
    16381 tccgtcaagc acttgcggaa ttagttgacg ttgatgcacg taacgtccat gcttacatct
    16441 taggtgaaca cggagattca gaattcccag tttggtcaca tgcaaatgtt gccggcttgc
    16501 aaatctatga atgggtaaaa aacaacccag aaatcgatga agaagctatg gttaacctat
    16561 tctttggcgt acgtgacgct gcttacacaa ttatcgagaa aaaaggcgct actttctatg
    16621 gtatcgcagt agcattagca cgtatcactc gtgccatctt agatgatgaa aatgctgttc
    16681 ttcctttatc agtattcatg aatggcgaat atggattgaa cgacatctac attggtgcac
    16741 ctgctgttat caaccgtcaa ggtatccaaa aagtaatcga aattccttta agtgacagcg
    16801 agcaagaccg tatggctgct tctgctaagc aattaaaaga aattctagat gaagcttttg
    16861 ctaaactaga cgctgaataa tctttgaaca tgacggaaaa catctattcg gtgttttccg
    16921 tttttttatt ttatcaccct tatggtttct aaattttttc ataaagtaga gataaccttc
    16981 gtcttttcct ctaaattatg ctatcatgag accgttccac cctaaacttt tacttaagga
    17041 gttgtcgata tgacaagatc ttcgcatcga aaaaaatcga aacatgttgc tttgctttca
    17101 gttcttggtg ttctcttagt gctgatcagc ttttatacct atcgcagtac atactacaca
    17161 aagcattttt tgccgaatac agaaataaat ggaataaatg tcagcaatct aacagtcgaa
    17221 aaagcaaatg aaaaattaaa agaagcttat tctgataaaa aactggctat taaagaagat
    17281 ggaaaagtct ggcaggaagt accaaaatcc gagctcggct acaaagatga tttcacttcg
    17341 gagctttctc cgatcctaaa tgaacaaaac ggatggactt ggggaatgac ttatgtctca
    17401 gcggcagaaa aacaagaaat agatcctgtc agtcaaaacc accaaaaact agacactacc
    17461 gttcagacat tgacaactaa gctgactgat ttgaacaaag accggacacc tactactgat
    17521 gcaacgatcg aaaaagcagg tgactctttc gttatcaagc ctgaagtcaa tggaaatacg
    17581 atcgacgtcg atgctgcggt caaacaatta aaaagtgcgg taaactctgg taaagataca
    17641 attgaattga ctgaattcaa agaaaaacca aaagtaacat ctgaagacag ctcactgaaa
    17701 gaacaactcg catccatgaa tgctatcgca aatgtaaaag ctacttacag tataaacggt
    17761 gagactttcc agatcccatc aagtgatatt atgagttggc tgacctacaa tgatggaaaa
    17821 gtcgatttag atacagaaca agtacgtcaa tatgtaacag atttaggcac aaagtataac
    17881 acaagtacga atgacacaaa atttaaaagt acaaaaagag gagaagttac ggtcccagtt
    17941 ggcacttaca gttggacgat ccaaacagac agtgagacag aagcattgaa aaaagcgatt
    18001 ctggcaggcc aagattttac tcgttcaccc attgtgcaag gtggcacaac cgctgatcat
    18061 ccattgatcg aagatacgta tatcgaagtt gatctggaga accagcatat gtggtattac
    18121 aaagacggaa aagtggccct tgaaacagat atcgtttccg gaaagccaac tacacctaca
    18181 cctgctggag tcttctatgt ttggaataaa gaagaagatg caactttaaa aggaacaaat
    18241 gacgatggaa caccttacga gagtccggta aactactgga tgccgattga ctggacaggt
    18301 gttggtatcc acgattcaga ctggcaacct gaatacggtg gagacttatg gaaaacccgc
    18361 ggttcacacg gctgcatcaa caccccacca agtgtaatga aggaattatt cgggatggtc
    18421 gaaaaaggaa cgcctgtatt ggtcttctaa caaaaataat atataaaaag aaagcacccg
    18481 tacgattggt acaggtgctt tctttttatt atctaacaat gtgctactta catttcagca
    18541 gcagtaaaga cttctgaaac atcatcatcg tcttctagct tatctactag acgttccaat
    18601 tgctcttttt gttcctcatt taaatcaatc gtcgtttgtg gaatcatcgt caattctgct
    18661 tgcgccaaag tgaactcttt ttccaactca tctcgtacag cagcaaaatc ttctggtgca
    18721 gtataaatct cgaatacttc aggagaagtt tgcagatctt ctgcccccgc ctctaataca
    18781 tcctcaaaca tcgtctcttc atcaacagtc aacccatcgc gttcaatagc gatatatcct
    18841 ttgcggtcaa acaagtaact gactgaaccc gtttctccca gtgatccacc gtttcgagta
    18901 aaagctactc ggacatttgt cgctgtccga ttacggttat ctgtcaatgc atggactaag
    18961 attcctactc cacccggacc atatccttca tacgtgattt catcgtaatt cgtttcatct
    19021 acggcactcg tagccttttt aatcgcccgt tccacattgt cgttaggcat atttgcagct
    19081 tttgctttgt ccacaacaag ccgcaaagct ggattcatag atggatcagg accgcctgct
    19141 ttagctgcca tataaatttc acgagaaagt ttctgaaaga ctttccctcg ttttgcatct
    19201 tgggcatttt ttcttccttg gatattatgc catttactat gtcctgacat gatttttcct
    19261 cccttgttct tttgagaata cacttctatt ctagtactat ttcacaaaaa aacaaagcca
    19321 cagccaatct ataaacgctt cttgaatgcc gcaaaaagca cacataatat cacagcagtc
    19381 agagcaccga tcgaatccaa catgacatct tggaacatag gtgttcgtcc accggtcatc
    19441 atctgatgga attcgtccaa acctgcgtac cctgttgctg aaagccaagc aaggatcgct
    19501 gtcagccacc aaatttttag cttggggaaa acacctaaaa acaagctgcc tcccaaaata
    19561 aaataggtac cgaaatgtgc gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc
    19621 agatggttga tactcaccat acttccacca taattaaaac gtatacccgc taatgtgtct
    19681 ttaaatggct gattaggcag ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa
    19741 gtttgagaag aactgtaaaa taagattata acgactatca gtgcgattac taaataaata
    19801 tttccgtttt tcatttgttt ttttgaagaa ttcataagtc acctctgtat tttatcttag
    19861 actttttttg aagaaacaac aatcattttc atagagactt cttccataaa aaagtgctat
    19921 acttaatttt gtattacaat atgaagggag ttttttcatg agttattcat taaattggaa
    19981 tctagattct attttttccg gaggcagtca ttctgatgct ttgaaccaac ggatgaagca
    20041 attggaagac caaatgaacg agtattatca ccgcgtaaca aaatggtcac ctagttctga
    20101 caatgcagag cagttaaacg ctattcttca attgcaagaa acgattacga atggttttac
    20161 ccaatgcagc agctatatta ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa
    20221 ggtcttatca ggcaagcttt acgcaatgct gcctcgtctg caatcagccg aaactgtatt
    20281 gtcaaagaaa tttgcagaaa tatctgacaa tgattggaat cagatgcttt ctcaatcttc
    20341 gtttgaaaca attgcttttc gtttaaacga gattcgtcgt gatggctcac aattattatc
    20401 agaagctgaa gaaaacatta taaatacgct ttctttagat ggtctaaatg cttggagcag
    20461 tcattatgat acgattgtag ccagcatttc gattcccttc gaacaagatg gacaagtagt
    20521 cgaattatct gctggacaag ccttcaataa gatgatgggc gatccagatc caaaagtcag
    20581 agaaacactt ttcgcagcat gggaagaagc ctggaaagaa aaggcacccc tcttcacgga
    20641 tactttgaat catttagatg gttttagact ttctgactat gaacttcatg gtgtcacaga
    20701 ttttctacaa aaaccattag agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg
    20761 ggatacaatc cagaaaaaca aacaacccct tgttaattac ttgactagaa aagctaatct
    20821 tttcggtaaa gaaaaaatgg aatggcaaga tcaagatgca cctattattt taggcgattt
    20881 gaaagaaaaa acctttagtt ttgacgaagc agcagcattt attatcgaaa actttaacaa
    20941 attcagtcca aaaatggcta aatttgccca atctgctttt gaaaagagct ggatcgaagc
    21001 agaagatcgt cctgggaaac gtcctggtgg ttattgtact gagttaccag aaacaaaaga
    21061 atcaaggatc tttatgacct acagtaattc tgttaatgag gttgcgacac ttgctcatga
    21121 actaggacat gctttccata gcagcacgat gtgggattta ccttctttaa atcgcgaata
    21181 tgccatgaat gtcgcagaaa cagcaagtac attcgcagaa ttgatcgtag ccgatgctac
    21241 attaaaagtc gcaaaaacaa aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa
    21301 tgctttagct atgttcatga atatccattc ccgattcatt tttgaaaatc gattctatga
    21361 agcacggcaa gaaggattag tctcagaaga taagatcaca gagatgatgg ttgaggcgca
    21421 aaaagaaggc tatcaaggag ctttagctac ttaccatcca tatttctggg ctgcaaaatt
    21481 gcatttcttt attgatgacg taccgtttta taacttccca tacacatttg gctacctctt
    21541 tagtttgggc atctatgctt acgccaacca aaagggagca aattttgaag aagaatatat
    21601 ccatttacta cgcgatactg cctcaatgac gacggaagat cttgcgaaga aacatttgaa
    21661 tgtcgatctt acccaaccag atttttggca agcaggtatc gacatggtga ctgaagatat
    21721 ccaaacgttc atggaattga cagaagaatt tatctgattt ctattttatc acaataaaaa
    21781 aagagttagt ccagaatggg ctaactcttt ttg
//
LOCUS       DADVXE010000045        21423 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.046, whole genome shotgun sequence.
ACCESSION   DADVXE010000045 DADVXE010000000
VERSION     DADVXE010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.046"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            299..1960
                     /locus_tag="KB913_001842"
     CDS             299..1960
                     /locus_tag="KB913_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6820200.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2392)
                     /locus_tag="KB913_001843"
     CDS             complement(2030..2392)
                     /locus_tag="KB913_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBB6820201.1"
                     /translation="MKEQSNEKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFL
                     WSLPFLIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLII
                     AGILIALSAIFMLFSLLG"
     gene            2460..3401
                     /locus_tag="KB913_001844"
     CDS             2460..3401
                     /locus_tag="KB913_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6820202.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3402..4445
                     /locus_tag="KB913_001845"
     CDS             3402..4445
                     /locus_tag="KB913_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6820203.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4451..5521
                     /locus_tag="KB913_001846"
     CDS             4451..5521
                     /locus_tag="KB913_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820204.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5511..6464
                     /locus_tag="KB913_001847"
     CDS             5511..6464
                     /locus_tag="KB913_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6820205.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6476..7486
                     /locus_tag="KB913_001848"
     CDS             6476..7486
                     /locus_tag="KB913_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6820206.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7771..8592)
                     /locus_tag="KB913_001849"
     CDS             complement(7771..8592)
                     /locus_tag="KB913_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6820207.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8689..8967)
                     /locus_tag="KB913_001850"
     CDS             complement(8689..8967)
                     /locus_tag="KB913_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820208.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9235..11244
                     /gene="metG"
                     /locus_tag="KB913_001851"
     CDS             9235..11244
                     /gene="metG"
                     /locus_tag="KB913_001851"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBB6820209.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11723..12310)
                     /locus_tag="KB913_001852"
     CDS             complement(11723..12310)
                     /locus_tag="KB913_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820210.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12485..13807
                     /locus_tag="KB913_001853"
     CDS             12485..13807
                     /locus_tag="KB913_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6820211.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13962..14738
                     /locus_tag="KB913_001854"
     CDS             13962..14738
                     /locus_tag="KB913_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBB6820212.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14731..15300
                     /gene="rnmV"
                     /locus_tag="KB913_001855"
     CDS             14731..15300
                     /gene="rnmV"
                     /locus_tag="KB913_001855"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBB6820213.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15293..16177
                     /gene="rsmA"
                     /locus_tag="KB913_001856"
     CDS             15293..16177
                     /gene="rsmA"
                     /locus_tag="KB913_001856"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBB6820214.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16628..17257
                     /locus_tag="KB913_001857"
     CDS             16628..17257
                     /locus_tag="KB913_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820215.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17381..18490)
                     /gene="ugpC"
                     /locus_tag="KB913_001858"
     CDS             complement(17381..18490)
                     /gene="ugpC"
                     /locus_tag="KB913_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBB6820216.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18699..19121
                     /gene="mgsA"
                     /locus_tag="KB913_001859"
     CDS             18699..19121
                     /gene="mgsA"
                     /locus_tag="KB913_001859"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBB6820217.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19444..19968
                     /locus_tag="KB913_001860"
     CDS             19444..19968
                     /locus_tag="KB913_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBB6820218.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKIWLFVK"
     gene            complement(20018..21319)
                     /locus_tag="KB913_001861"
     CDS             complement(20018..21319)
                     /locus_tag="KB913_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6820219.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         6914 a         3852 c         4370 g         6287 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgtggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt tttcatttga ttgctccttt atttttggtt
     2401 cattatctaa taatgtagcg aaacatctgt cagaagtcaa aagctagggg gaaacattag
     2461 tgaatagtta tatcaaatat gtattaaaac gtgtcttttt catgatcatc acgctttggt
     2521 taattgcaac aatcaccttt ttcttgatgc aattgctgcc gggcacgcca tatacgaatc
     2581 aggaacgttt gagtcctgaa acaatcgaga tgctaaataa acaagtcggt ttggataaac
     2641 cagttatcgt acaatatggg atttatcttt ctaatttgct tcaaggagat tttggaattt
     2701 ccttccaatt taaaaaccag ccagtcgcac atttgttagc tggaagaatc ggaccatcct
     2761 tgcagttagg gttacaggca attatctttg gaacagtcct agggacgatt ttaggaacga
     2821 tctctgccat gaagcaaaat acatgggcag atacatcttc tacactcgta gcgatattag
     2881 gtcgttccat tccaaacttt gtatttgctg ttttattaca atatatcttt gcaatcaaat
     2941 tacaagtttt gccaatcgca aaatgggatg gctttgtgta cacaatctta ccaacaattg
     3001 cgttggccat gtcgccgctt gctgactctg ctcggtttat ccgtacggaa atggtggaag
     3061 tactgcatag tgattatgtg gaattagcaa aagcaaaagg attgagccgt tgggaaatcg
     3121 cctttaaaca tggtcttcga aatagtttga ttccattgat gactttatta ggaccgttag
     3181 ctgtagcatt gatgaccgga tcactggtgg tagaaaatat ctttgctatt cctggtatcg
     3241 gggaacaatt cgttaagtca atcacaacaa atgattatcc tacgatcatg gctgtaacga
     3301 tcctttactc atttatgctg atttttgtta ttttgatcgt ggatctattg tacggtctag
     3361 ttgatccaag aattcgtgtt tcagaaggga gccgaggata aatggaaatg ataccaaagc
     3421 gttatgaaac agttgcagat atccctgcgg atgaatttct tccattacaa aaaaataccg
     3481 aagaagaacg tgaacagatt actgcacctt ctttgaattt tatccaagat tcatggcgcc
     3541 gtttaaagaa aaacaaagct gccgttattt caatggtttt actattggtc atcattttga
     3601 tctctgtgat cacaatcttt gtttctcctc atgatccaac tgcccaaaac gtggcttata
     3661 tcaatttgcc tcctcgtatt ccgggaatca atatcgatgg attgaatgga aaagcaatgg
     3721 ttggtggtga acttgttgat aaatatgctc aagcaaacgt cccttcaaac gtaaatttct
     3781 ttttaggaac agacggtttg ggacgtgatg tattaagccg cttatttatg ggaatgagaa
     3841 tctcgttgct gatcgcattt attgctgcat tactagatgt aacgattggt gtagcttacg
     3901 ggttggtttc tggtttgtta ggcggacgtg tcgataacgt gatgcaacgt tttttggaaa
     3961 tcttatcagg aattccaaac ctcgttgtca tgattttgat gttggtcgtt tttgaaccag
     4021 gaattttttc aatcgtggct gctatggcca tcacaaactg gataccaatg gcacgtatcg
     4081 ttcgtgcaca aacaatgaaa ttaaaagatc aagaatatgt tttagctgga ttgacattag
     4141 gtgaatcaag aatgaaaatt gcattcaaac atattttgcc gaatatctct agtgtcatta
     4201 ttattcaaat gatgtttagt attccatctg ctattttctt cgaagccttt ttaagcttta
     4261 tcggtttagg tcttacgcct ccgtcagctt cattaggaac gatgttgagc gaagggtaca
     4321 agacattcct gtatctgcct tatctattat ggattccggc agtaacttta tcggttatca
     4381 tgattggctt taacttactt gctgatggat tgcgtgatgc ctttgatcct aaaatgaaag
     4441 agtgaagacg atgacgaaaa ttttagaagt gaaagactta gaaatctctt ttgatacgta
     4501 tgctggaaag gtacgagcga ttcgcggtgt caattttcat ttgaataaag gagaaacatt
     4561 ggcgatcgtt ggggaatctg gaagtggaaa atcagtgacg accagaagca tcatgcgctt
     4621 gctgtcaagc aacgccaata tagatgctgg tcaaatcctc tttaaaggta acgatatcgt
     4681 tggaaaatca gaaagagaga tgcaaaaaat ccgtggtaaa gaaatagcga tgattttcca
     4741 agatccaatg acctctttag atccgacgat gcccattggg aagcaagtcg ctgagtccct
     4801 tagaaagcat aataaagttt caaaaaaaga gggacaaaaa gctgcattag aattgcttaa
     4861 attagttgga atacccgaag ctgagaaacg tatcaacagt tatccgcatc agttctcagg
     4921 aggtcagcgt caacggatcg tgatcgcgat tgcactggta tgttatccgg aaatcctgat
     4981 tgctgatgaa cctacaacag cgcttgatgt gactattcaa gcacagattt tggagctgct
     5041 gaaagaaatt cagacaaaaa tcgatacatc aattatcttt atcactcatg accttggtgt
     5101 agtagcgaat gtcgctgatc gtgtcgctgt catgtatgga ggaagaatcg ttgaagttgg
     5161 aacatcggaa gaaattttct acaacccgca acatccctat acttggggac tgcttggttc
     5221 aatgccgaca ttagatagtg cgaacgatcg attgtatgct attcctggtt ctccaccgga
     5281 tttattgaac ccgccaaaag gagacgcatt ctatccaaga aatgaattcg cgatgaaaat
     5341 cgatgcagaa caagaaccac cattttttga actatcaaaa acacacaagg cagcaacttg
     5401 gctacttgct ccgcaggcac ccaaagtgac accgccagaa gaaatccaac gtcgctgggc
     5461 tatctttaaa gagaaacaaa aacatactta cggtcaagga ggaattgctg atgccaaata
     5521 aactacttga agttaaagga ttgaaacagt atttcaatgt aggaaaaaag aatgaagtac
     5581 atgctgtaaa tgacatcagc tttcacattt atgaaggaga aacattcggt ttagttggag
     5641 aatctggaag cggaaaatcc actactggcc gtacgatcat tcgcttgaat gaacctactg
     5701 atggtgagat attattcgac ggtcaagata taacgaagat caaagataaa aaaggtttga
     5761 cgaaattccg gcatgatgtt cagatgatct ttcaagatcc atacgcttcg ttgaatcctc
     5821 gtatgaaagt cagagatatc attgccgaag gaattgatgt taatggacta gctaaatcat
     5881 ctgaagagcg tgcaaaaaaa gtcgatgatc tattgagaac tgttggattg aatccaagcc
     5941 acggtactcg ttatcctcat gaattttcag gtgggcaacg ccagcgtatt ggtattgcac
     6001 gagcattggc agtaaaaccg cgttttatca tttgtgatga accaatttct gcactagatg
     6061 tgtcgatcca agcccaagtg gtcaatttgt tgcaagatct ccaaaaagaa catcaattga
     6121 cctatctatt tattgcacat gatttgtcga tggttaaaca tattagtgac cgaatcggtg
     6181 taatgcataa cggcttgtta ttagagatgg gaacaagtga tgaaatctat aatcacggtg
     6241 ttcatcctta tacagaaagt ttgttatctg ctattcctct accagatcca gaccatgaga
     6301 gaaaacgcag aagaatcaaa tatcaacctg aaccagatga cggacaagta cgtcaacttc
     6361 gtgaaatcgc accagaacat tttgtctatg caactgagca ggaagtccca tattacgcaa
     6421 aaaaactaaa acgacaaaag gaatctcttc tggttgctaa ctaggaggga catagatgct
     6481 aaaagctttt aaattccgta tgtatccgac agaagaacaa aaacagcaat tgattcgtac
     6541 ttttggatgt gctcgattta cctataacca tttgctgaaa aagcggcaga aaagttggca
     6601 acaaacagga gtagccaatt tttcgctcac acccgctaca ttaaaaaaag aatacccatt
     6661 cttaaaagaa gtagacagtc ttgctttagc aaatgcacag cttaatttgg atcgggcttt
     6721 tcgcaattat ttcaagggac gtgccagctt cccaaagctt aaaacgaaaa aaagtatgtg
     6781 gcaatcttat acgaccaaca accaaacccg tacgatctat ctggaaaatg gctacttaaa
     6841 gttaccaaaa caaaaagaac taatcaagat aaatcagcat cggccagttg aaggatcgat
     6901 tcgctccgct acgatttctg ctcgatataa tgaagaattt tatgtcgcac tactttgtga
     6961 tgtttcgcca gtaaaaaaag aatctttagc taaatggatc gggatcgcct atcatccgaa
     7021 gacattgatc caaacatctc gacctctaga agtaacttta ccaaaatttc accagacaga
     7081 agaaaagctg caacatgcac agcggaaatt gaatgtgaaa gtccgctccg ctcaccatag
     7141 aaagatcagg ttagatcagg caagcaatta tcagaaacaa aagagaaaag taatggatct
     7201 ttatctgaaa caaaagaacc agcgagaaga ttatcttgaa caattatctg ggaaattggt
     7261 caaacaatat gactacttat ttgtagaatc ttttccaaaa gaagaggcac atgctgattt
     7321 ttctattcac gactggcata aattaataac aaaattgcgt tataagtccc aatggtataa
     7381 taaaaaattt cttttgatca ataccgacgg agcagaagaa agcaattccg taagaaagag
     7441 ccaagtagta gaaaaaatgg gcagacattc ggttatcaag ggataaaaaa tgaatgaaac
     7501 tgataggagc gttagggtta gccttgttaa taaaaagtct taatgacttt tgtttctagg
     7561 aatttttctt ttgaagaaaa gctcactaat tatgacaaac caataaaaca atagcagaaa
     7621 aagttcgtac gagctttttc tgctattgtt aattttttat tcagaaagtt tacgaataca
     7681 tcaaaattct gaaacaaaaa acgtaactca caaagagttg tttttgcgtt ttttcttgaa
     7741 tgattaggtc tgaatctttt gctcacaacc ttattcatgg tgccccggct tgagctgata
     7801 gatttttgaa ggacggccga ttcctacagg acgttcaccg atctcatcga aatattggag
     7861 catagctttc ttaaaattgg aatgatcgat cgttttataa tcgatcccta agaatttagc
     7921 aaatactttt cgagcttccg taatcgtgaa atctttacct aaaacttgta gaacttgcgg
     7981 ctcgtgttcc attttattga ctacacggtt gaatgctttc aagatgattt gactatggtc
     8041 aaaagccaaa gtatctttgc cagaagactc tccagtgact aaatcaagcg agatagccac
     8101 ttctccgcta gataaatgga tcttgttact atgacgttct agtgtgaacc agcgtacttc
     8161 cttggcatca tctccggcga ttagcggttc ttctccaata aaggctaagt agctgactgt
     8221 gacgacccag cctcgcggat ctcgattagg cgtactgaat gtatgcagtt gctcaatatt
     8281 ttcttttgaa ataaccacac cagtttcttc ctttgtttct cttaagacgc tttctccagt
     8341 tgactcatcc ttttggacaa agccaccagg caatgcccat gaatttcgat aaggatgccc
     8401 ttttctttgg atcaacaaaa ctttcagctg atcttcttct ttgttatagc acatcagtac
     8461 gatatcgaca gtcaaagagg gcttgtcata ttctggacgt tcctgttttt gataccagtt
     8521 aagaaattct tcttcacttg ctttatgttc ataatataat ttttcttctt ctttagaagc
     8581 aaaacggttc atctgaccac ctccattgac agtaaaagta ctttttacct tattgtagca
     8641 gactctgaaa aaaaaccaag gatttacttg aaaaatctag gttatcattt aaatatgaaa
     8701 aataaatgga agtatgagat tgaataaaaa gaaaagcaga taaaacggca atactttata
     8761 ccgctcttca cgaatggcaa agaagccaca aataacgata tatacgtcaa tgataaaacg
     8821 caaaatccaa gctgctgtca taaaactgtt caaatgccca tggaggttaa aataaccata
     8881 catacgaata taaaaatagc tgaatattaa atgtgctaat gaaagaaaag caatactaag
     8941 tgtaaaaaaa agatgtttct tctgcatgat tgttccagtc ccttactaag atagatagtc
     9001 tttattatac cacgtgtgag gggagaaata aaaagccgtt ttttagtaga tatgaaacaa
     9061 aacaaaaacc cgcatttatt caacctattc atccttttaa aggatagatt gaacgtagat
     9121 agaagtcgtt tatccagtct ttttcatttt gaaaaaaagc taacagcatg ctttttttat
     9181 ggtatactag caaggaaacg aattcgcatc atgcgataaa ggaggaagag ccccgtggca
     9241 gaaaaggaaa ctttttatat cactacgcca atctattatc caagcggcaa acttcatatc
     9301 ggcaactcgt atactacgat tgcatgtgac gcaattgctc gttataaacg gttgatgggc
     9361 tttgatgtgt tttatctcac tggagtggat gaacatggtc aaaaaatcga aacaaaagca
     9421 gaagaactag gtgtaaaacc gcaagaatat gtagataaaa tggcggctga tgtcaagaaa
     9481 ttatggaaaa cgcttgatat cagttatgat aaattcattc gcacgacaga tgattaccat
     9541 aaagcagctg ttcaaaaaat atttgatcgt ttattagaac agggagatat ttacttaggt
     9601 gaatatgaag gctggtactc tgtttctgac gaagaattct ttacagaaac acaacttgca
     9661 gaagtgtaca aagatgacga aggtaacgtg atcggtggta aagcgccaag tggacacgaa
     9721 gtagaattgg taaaagaaga atcatacttc ttccgcatga gcaaatacgc agaccgtcta
     9781 ttggaatact atgaagaaca tcccgaattc atccagccag aatctcgtaa aaacgaaatg
     9841 atcaacaact ttatcaaacc aggattagag gatcttgcag tttcacgaac aacttttact
     9901 tggggagtac cagtcaagag tgatccgaaa catgtggtgt atgtatggat cgatgcatta
     9961 tccaattata ttactgcact aggatatggc tccgaagatg aaagtctatt cgaaaaatac
    10021 tggcctgcag atgttcagat ggtcggtaaa gaaatcgttc gctttcatac gatctattgg
    10081 ccaatcatgc tgatggccct tgatttgcct ctacctaaaa aagtatttgg gcatggctgg
    10141 ctattgatga aagacggaaa aatgtctaaa tcaaaaggaa atgtcgttta tcctgaaatg
    10201 cttgtggaac gttatggttt agatgcactc cgttattatt tgcttcgtgc tgttccgttt
    10261 gggtcagatg gtgtctttac gccagaagat tttgtttccc gtgtcaatta tgatctggca
    10321 aatgatctag ggaacttatt gaatcgaacg attgctatga tcaacaaata ttgtgatgga
    10381 ctcgttcctg actatgcctc acttgtcact ccatttgata gtgaactgtc tacgacggct
    10441 gctaacgttg tcggacgtta ccatgatgca atggaaaaaa tggaattcaa tacagcattg
    10501 gctgaaatct gggtgctgat ttctcgtgca aacaaataca ttgatgaaac agaaccatgg
    10561 gtattagcaa aagacgaaga aaagaaagct gaattgaata gtgtcatgat ccatttagct
    10621 gaatctttgc gtatcgcagc gatattactt cagccaatca tgacagaaac gccagagaag
    10681 atcttcaatc aactaggatt ggactctgaa acaatgaatc ttgaaggatt acactttggc
    10741 gaatttcctt caggaacaaa agtagttgca aaaggtacac caatcttccc acgtttagat
    10801 atggaagaag aagttgcttt tattcaagaa aaaatgtctg aaggtactca aacaaacgaa
    10861 gatacagtca aatgggatcc agaagaaaca gaacttgttt caacgaaaga aaaacaaatc
    10921 aaatttgatg tatttgaaaa agtagaacta aaagtagcag aagtcatcaa ctgtcaaaaa
    10981 gtagaagggg cagataagtt gctgcaattc cgactagatg ctggagacag ccaagaccgt
    11041 caaatcttgt caggaatcgc tgaattttat cctgatccaa gcgaattgat cgggaaaaaa
    11101 gtcgtcattg tagcaaatct gaaaccacga aagatgcgtg gacaaatcag tcaaggaatg
    11161 atcctttctg cagaagcacc agatggctct ttacaagtaa tcgaagcacc aaaatccatg
    11221 ccaaatggct cagaaatcgc atagaaattc aaagggggta tgacactagt tgtgtcatac
    11281 cccctttttc cgaaatttga gaagcaattt tcgtaaattc cttcttatta cttgaagcca
    11341 atcatataat acagaaacag agaactatcc aaaataaatc ctagaaaaag aagtacgagc
    11401 ttcgctgatt tttgttaatt tagaataata ctaataggaa tcgtaaaaac agaaaaaaag
    11461 cataatgata aagggtcggg cagattttaa ttgattcatc tggtactctt ttttattgtc
    11521 cttacattca taaagtttga atgcaatgac tttattacat ctatatttat atctaacagt
    11581 agcgttgatg tgttaattat aagttctatc actttatgtt caattagttt gtgctcttat
    11641 atgtgtgatt gaaaatatag ataaaaaaac aatcatcggc tttgacttcg atgattgttt
    11701 tctttatttt gtaaaaatcc tatcacttga ttttatggta accttttatt tttgtcttca
    11761 aacggcttgg taagagagca gtaagcagtg caaatgggat cgaaaagaca taccagaaaa
    11821 tcgtacgtcc gataccataa tgttgataga gctttgtcaa catcacgtgt aacaagatca
    11881 accctaaaag caaggagcca gctataaacc aatgattatc ccaatgcatg acttcactaa
    11941 gtgccatcac tccaaaagga tagaaataaa aatagatccc gactaaggtc atccgccagt
    12001 tctttgtaaa tgttccgata ttcaataaaa agaaaatcgc tgaaagcaaa ataccgatag
    12061 gcggaaaaag cccaaccaaa aaggaataca acatccccca caagatcatc acaggacctt
    12121 tgatcaatgc aacgattgcg atgaacaaag tcagcaatat tagtttttgt gataacgttg
    12181 caacagtcat taatccaaat aaaattaatg tgaaccaatg ccaatgggac tgctgttgtt
    12241 ctttacggga aaaatcgacc cggttggata aataatctgc taatttcgga taagaacgct
    12301 taaaatccat aaactgttcc tccttcgtgg aaaaggtagg tttagtatac gaaaaataaa
    12361 aaagaaatac atccgtctta agagggagtt tttcactgaa agtggagaaa aaagaatggt
    12421 aaattaaaat attctcagtt atactgaaaa ttataccaaa tttcaaagaa gaaagaggat
    12481 gggaatgaaa ggcaaactaa aacgagaaat caatctgttt ggcgcattag ctaccgttat
    12541 gggaaccgtg atcggtgcag gcgtcttctt caaaactgct gctgttactg ctagtactca
    12601 gtctacaagt ttgacattgc tagcttggct tttgggtggt ttcttaacga tctgtgctgg
    12661 attgacagtg gctgaattag ctacagcaat cccggaaact ggtggagctg taaaatatat
    12721 tgaagctgcg tatggaaaat tgcccagctt tttattagga tgggcgcaaa gcttgattta
    12781 ctttcctgct aatattgctg cattatcgat tatctttgcg acacaattga cgaacttatt
    12841 acaattatct accgattatc ttttgttgat tgcagtgatc accgctgttt ctgtgacagg
    12901 gttgaatttg ttagggacaa aagtcggtgc ttctgtacaa tcagtgacgt tgattgttaa
    12961 attaatacca attgctgtga ttgtcatatg gggattattg accccaggac aaggaactgt
    13021 ccagttattt ccaatcgaag ctggaaaaga tgttactttt gtcgaaggat tgagcagtgc
    13081 gttgttagca acgttgtttg cttatgacgg ctggttaggt gtcggtgcaa tggcagggga
    13141 aatgaaacgg ccggaaaaag atttgcctaa agcaattatt cttggtttga gttttgtaac
    13201 agtcgtttat ctattgatca attttgtttt tttgaaaact ttgccgattg atcatcttgc
    13261 cggtaatttg aatgcagctt ctgaagcatc agacgtcatt tttggaggaa tcggtggaaa
    13321 gctggtcact attgggatct tgatctcggt atacggtgca ttgaacggtt atacactaac
    13381 tgggatccgc gtgccttatg cgatggcttt agaagacgag ctacctttca gtaaacagct
    13441 gacaaagctt tcaaagaagt ttacggttcc ttatgttcct gcggttttcc agttagcagt
    13501 agcttgtatt atgatgagcc ttggttcttt cgacttttta acagacatgt tgatttttgt
    13561 gatgtggcta ttcagtttac tgatttttat cggtgtcttt attttaagaa aaaaagcgcc
    13621 ggaattgcca cgtccatata aagtaccact ttatccaatc gttccgatta ttgcgattct
    13681 cggtgctatt ttcattttag gtatgacgat gatgacgcaa acgaaattag cattgatcgg
    13741 tataggtgtt accttgatag gtatcccagt ctattatcaa aaaaagaaaa aacgctcaga
    13801 agagtaaaat atttcaacaa cagacagaaa aagtacgaac taggtcctct agatcttcgt
    13861 gctttttcta tttcaataaa acaagttctt ctattttgat ttttgctact tctgcaagta
    13921 gtgcttatgt gctaaagtaa gaatgaaaag gagagataaa catgatattt gattctcata
    13981 cccatttaaa tgctgaacag ttcaatgaag atattccaga aacgattcag cgagcacaag
    14041 aaatgggggt aacgaaaatg gcggtcgtgg gcttcgatac gccaacgatt gaaaagtctt
    14101 tgcaattaag ccatgactat ccaaatatat acagtattat cggctggcat ccgacagagg
    14161 ctggcagtta tacgaaagaa atcgaaaata aattacaaga acaattgact ttaccaaagg
    14221 ttgtagcatt aggggaaatt ggcttggatt atcattggat ggaagacccg aaagaagtcc
    14281 aagataaagt atttcgcaga cagattgcta tcgcaaaaga aatgaaccta ccaatcagta
    14341 ttcatactag agaagcactt gaagacacgt atcaaatcct aaaagaagaa gatgttcgag
    14401 atatcggtgg aatcatgcat agtttcagtg gtgattatga atgggcaaaa cgatttcttg
    14461 acttagggat gcatatttca tttagcggtg tcgtcacttt caaaaaagca ttagacgtcc
    14521 aagaggctgc agcaaatgta ccaatcgaac gattacttgt ggaaacagat gccccttatc
    14581 tggcaccagt tccttttaga ggaaagcgaa atgaaccagg ctatactcgt tatacagtag
    14641 aaaagattgc tgaacttcgg aatcttccga cagaagaagt ggctgcccaa acatggacaa
    14701 atgcgcaccg attatttggt ctaagcgaac atggataaga tgaagatcca agagattata
    14761 gtcgttgaag gaaaagacga tacaagaagg ctgcgggaag tagttgatgc agatacgata
    14821 gaaacaatag ggtctgcaat caatgaagag atcctgatgc aaattgaaca tgcccaagag
    14881 actcgtggag tgatcgtttt taccgatcct gatttttcag gagaaaaaat aagaaaaatc
    14941 attatggaag ctgttcctca ggcaaaacat gcttttttgc cgcgcacaca agctaaacca
    15001 aagaaaaagg gaagccttgg tgtcgagcat gcaagtgatg ctgctatttt agaagcattg
    15061 aaaaaggtcg tgacgccaga catttcccaa acggctgttt ctgaaatcac tagacaagac
    15121 cttttagact atggtttaat agctggggca caagcaaaag aaaaacgaga aaaactaggt
    15181 gacgagttgc gcatcggtta cacgaacggc aaacaattgg aaaaacgttt gaagatgttt
    15241 cgtattacgc cgaaagaact cgcccaagca atgaaaatag tggaggaaca acatgagtga
    15301 atatcgtgaa attgcgacac cctctagaac aaaagagatt ttattgaaac atggtttttc
    15361 atttaaaaaa agtttaggac aaaattttct gactgaacca aatattttaa ggaaaatcgt
    15421 agaaactgcg caaatagatg aacatacgaa cgtgatcgaa gttggaccag gaatcggtgc
    15481 attgacggaa caattagcca agcatgcaaa acaagtcgta gcatttgaga tcgatgatcg
    15541 tttgatccct gtattggctg atacgatgca accctatgac aatgtgacta ttgtacatca
    15601 agatatttta aagaccgatt tgtcaacagc tgttagagaa acatttcatg aggagcttcc
    15661 gttaaaagtc gtagcgaatt taccttacta tattacgaca ccgatcatga tgcattttct
    15721 tgaatcagat ttggttgtgg atgaactagt cgtcatgatg caaaaagaag tagctgatcg
    15781 tatctctgct gaaccaggaa cgaaagctta tggttcatta tcgattgctg ttcaatatta
    15841 tatggaagcc agtttagcat tcatcgtacc aaaaacagta tttgtccctc agccaaatgt
    15901 agattcagcg attttgaaac tgacaagaag agatataccg gcagtcgaag tgacagacga
    15961 aaaagcattt ttccgattga caaaagcggc atttcagcaa agaagaaaaa cgctttggaa
    16021 taacttgcag cattcgtatg gcaaagatga ccagacaaaa gcatggttag caaaaagctt
    16081 ggaaacagct ggaatcgatc caaaacgtcg tggggagact ttgtcattac aagaattcgc
    16141 cgcattaagc aatgcgatgt cagaaaatat gcagtaaaaa aagaggttgt gacagaagtt
    16201 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa acaaaaatag ttcctcatgt
    16261 ttttcgtttg tttgggctta ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga
    16321 ggttgtgggc ctgccgttta actctaagtc acaaggaaca atttcaaaaa acagcttctc
    16381 atgtttttga gttagttggt cttattactt gatgcaagct tttgaccact attatgccga
    16441 acaaggagat gtgacacaaa ttttgtcaca tctcctattt ttgtttcttg atcaaaaaat
    16501 tcttatactt gatactcaca ctcattttgt atggatttag aaaagaatat gtgtcttgac
    16561 agttattagt aagtgagtta tactaagtcg acatttatgt gtcaagacat attaggagag
    16621 agaaaaaatg agaaaaaatt cagttcgaaa actaacgatt tctgctttat tgattgggat
    16681 gggggtcatt atcccaatgg tcatgcctaa aatcatgatt ccaccagctt cctttacttt
    16741 ggcgtctcat gtgccattat ttattgcgat gttttttaca ccaggagttg cagtggctgt
    16801 tgcgctaggt acgacatttg gtttcttttt aacaacgccg gttatcatcg cattgcgagc
    16861 attgtcacat cttgtgtttg cgttgattgg ggcttggtac ttgcaaaagc atccgagtat
    16921 cgttttaaaa aatggacagt ttacttttgc taattggcgt ttccaagggt tcaattttgt
    16981 gatcggtgtg attcattctt tagcagaaat gctagtagtc agcatctttt actttattgg
    17041 taatatgcct gaaacatatt attctcaagg atatttttat acagtattca tcttgatggg
    17101 gattggtggg cttatccaca gtttagttga ttataatatt gcttatttta tagcaggaac
    17161 actcagcaaa tattttgata tccccgtatt tacggcagca aaaaaagaaa atcggaaaga
    17221 gtcgattcaa gggtacgcga agaaaacgac atattagaca tgatctctca aaaaaaaaac
    17281 tctcatctag taatggataa taaatcctct aagatgagag ttttttgtcc taaaaagagc
    17341 tgcaccaaca tcttctggca cagctctaac agggggcaat ttatggaagt ttgatgactt
    17401 gttctgtttc tttatcaaag aagtggcctt tgctgatgtt gaaggcaagg tcgactattt
    17461 cgcctggttt atggaaatct cttgcatcta cttttgagat gaactcagta gaaccagttt
    17521 ttgtgtaaag catcgtttca gctccaagta attcggaaac gacaacttct gatttcacta
    17581 cggcttcagg tgaagcttca agggctactt gttcactgtg gatgtcttct ggacgaatac
    17641 cgaagataac ttcttttcct tcataacctt tttcaactaa tactttgttt tttccttcag
    17701 gaatacgaag cttaagccca tgtccatctg tgataacacc atttttcaat gtcacattaa
    17761 agaagttcat ggcaggagat ccaataaagc cggcaacgaa catattgacg ggtgtatcat
    17821 aaacttcttt cggtgtaccg atttgttgga taaatccgtc tttcatgata acgattcggt
    17881 cagccatagt cattgcttct gtctgatcgt gagtaacata gatggtcgtt gtttcaagac
    17941 gctggtgaag tttggcaatc tcagcacgca tggctacacg taatttagca tctaaatttg
    18001 ataatggctc atccattaag aagacttttg catcccgaac gattgcccgt cccaatgcca
    18061 cacgttggcg ttgtccacca gataaagcag ctggttttcg tttcaagtat tctgtcagac
    18121 ctaagatctc tgctgcattg tccacacgtt ttttgatgtc tgctttatca tatttacgta
    18181 atttcaagcc aaaagccata ttatcaaaaa cagtcatatg aggatacaat gcgtagtttt
    18241 ggaaaaccat ggcaatatca cggtctttag gtgccacgtc attcatgact tttccgccga
    18301 tatttagttc tccttcagag atatcttcca gtcccgcgat cattcgcaaa gtagttgact
    18361 ttccacaacc ggaaggacca acaaaaacga taaattcacg gtctttgatt gatagattaa
    18421 aatcagttac agaataattt tctgcattgt catatttttt atatacgttt ttcagagcca
    18481 tttctaccat aatacgttcc acactttctt ttttagtttt attaactatt taaagtataa
    18541 atgaaagcgt taactaactt caatgtcatg ttgaacaaga attttttctt ttttttgtca
    18601 atgtgctagt tttaagcttt aataaatatc cataagaaat aaaaactgat acactggagt
    18661 aaataagtat gttaacaata tcaaaaggag tgtctcttat gaaaatcgct ttgatcgctc
    18721 atgaccgaaa aaaacctatg atggtgaaat tagcaacagc gtataaaaca atattggaaa
    18781 aacatgaact ttttgctacc gggacgactg ggcagaggat cacggaagca accggcttgc
    18841 cgatccatcg gtttaaatcc ggaccgttag gcggggatca gcaaattgga gccatgattt
    18901 cggaggatca gttagatttg gtgatttttc ttcgagaccc gctggctgca cagccccatg
    18961 aaccagatgt aacagcactt atccgtttat ctgatgtcta tgagattccg ttagctacga
    19021 atatcggaac agctgaggtg ctactaagag gactggaagc cggcttccta gattttcgaa
    19081 gaatcgtcca tgaaatagac aagcatccac tttcattttg atggataagc gtatggaaaa
    19141 ataacgttta atgttcgcct atatgtagct ataaaagcta aacaaactga taatatgcga
    19201 tataatacga acgtattgga taatataaac aataatatta gtttttcgta tttgcagtaa
    19261 atgtgaaaat atgctatagt ttctgtggga aaagatccca aaaataatac agagtagaaa
    19321 ataaagcgtt aagtgctaag aggatgggat gttgcctctt ggacgaagga cgtaatgttc
    19381 gcggttttat tttcgcattc gctgcatgat acgatgtagc agctcttaaa ggagatgcta
    19441 aaaatgaaga aacaccggtt agacgcacgt atgattgcta ttatgggctt attgattgca
    19501 ttgatggtca ctttgtcccg actggtagca atcgagaccc catttattaa aatcagtgtc
    19561 acatttattc cacaagtgat catgggcatt ctttttggtc ctttttggtc agggataggc
    19621 gcagttttag ctgatttagt aggaatggcc ctcttctcga aatctgcatt ctttattgga
    19681 tttacattga atgcatttat tgaaggagca atctacggat tctttttcta tcgaaaagag
    19741 atcacttgga aaaatgccat tctggctacg cttagtgtca cgctgatcat caacttattt
    19801 ttgacaccat tatggcttgc gttgatgtac catgtgccat tgttcagctg ggtcgtttgg
    19861 gcgccccgcc tgttaaaaac agtaatatgg ttaccgattc aatcaattgc catttattac
    19921 gtaggacgta gtattcctta caaaaaaatt tggctctttg tcaaatagga ctgatagagt
    19981 gagataagaa catctaaggt agaattcctt ttctacttta gatgtttttt gattcatagg
    20041 taatcagatt atttagtaag aaaattctgg tcttcatttt ccgaaagctt cgaaagccat
    20101 aagcgactcg tttcaatgct ttgatgtggg tatgcagatt ttctattttg gcatttgaat
    20161 aaggcaattc gagggctaaa cgaatgccgg attcatagtt tataaaagct ttttttatag
    20221 aatgcagttc ttttggaacg gaattgggca tcgttcttac aagtttaaag aaagtgtccg
    20281 cctctttgtc gtgaaacgct tgaagaattt cttgatagta aaaataggcg attcgtaatt
    20341 cgtcagagat cgaaagcaga cgatccacca cttcactttc ggtgagatac gcccaaccaa
    20401 aattgcgcca tttggtccat ttgtcataaa caagcttgtc ctgtcgtttg atcagaagcc
    20461 gagacaacgc ctttaattgt cgataatatt tggcttgtgt tggatcgttt cgatcaaagc
    20521 ttttcatgat tcgtacgcga atatcctcaa atttacgaat gagatgtttg acaatgtgaa
    20581 aacgatccac aacgagtttt gcctttggaa aacattcctt tatcagagag gcataagaaa
    20641 cattcatgtc cgtcacgatg acctttacct tcaatcgtgc gcgtcgttca aattgcataa
    20701 aataagaaac gagagccttt ttcttccgtg aaggaagaat atccagtaat tttccagtat
    20761 cgccatccat acaagaaaag gagtagggac cgacttgatt tttcagtgaa cgaaattcat
    20821 ccattaataa acaacgcggt aaccaatttc tttttacttt tgtcatgggg atcagagaag
    20881 cgagtgtccg agaaacggtc gaccaagaaa cgccgcaatg cttagcaatt gtcgtcattg
    20941 cttgtttttc agttagctct tctaaaattt tatagcgcac ttgtttagcg ataaagcagt
    21001 ttctatcgac aatgtaggta ttcgccgtaa aataggtgtg gcagccacga cagtggtagc
    21061 gttgtttcgc taaagcaaga taagtcagtt ggttcgcaca tttattaagt tgaatgagcg
    21121 attttttctt tccgttctta acgatcatgc cttcatgatt catctgttta cacaaaggac
    21181 agcgacgaat ttctttactt aacgtcgcag aaacaacaag actcttgata ttcttaatgc
    21241 tcttcgattc cacatttgtg atgaaaatgt ttttatcttt gattccaagt agtagtttga
    21301 tatgatgaag atcaggcata cagaacgctc ctttgattgt gttgtggtga ttcaattcta
    21361 acggagcttc tgtatgtttt gttttttcat gctcaaaagg gaccgataga atgattttct
    21421 atc
//
LOCUS       DADVXE010000046        21391 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.047, whole genome shotgun sequence.
ACCESSION   DADVXE010000046 DADVXE010000000
VERSION     DADVXE010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.047"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            72..773
                     /locus_tag="KB913_001862"
     CDS             72..773
                     /locus_tag="KB913_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6820220.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1382..2398)
                     /gene="tsaD"
                     /locus_tag="KB913_001863"
     CDS             complement(1382..2398)
                     /gene="tsaD"
                     /locus_tag="KB913_001863"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBB6820221.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2395..2859)
                     /gene="rimI"
                     /locus_tag="KB913_001864"
     CDS             complement(2395..2859)
                     /gene="rimI"
                     /locus_tag="KB913_001864"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBB6820222.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2866..3408)
                     /gene="rimI"
                     /locus_tag="KB913_001865"
     CDS             complement(2866..3408)
                     /gene="rimI"
                     /locus_tag="KB913_001865"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBB6820223.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3392..4114)
                     /gene="tsaB"
                     /locus_tag="KB913_001866"
     CDS             complement(3392..4114)
                     /gene="tsaB"
                     /locus_tag="KB913_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBB6820224.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(4305..5285)
                     /locus_tag="KB913_001867"
     CDS             complement(4305..5285)
                     /locus_tag="KB913_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6820225.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5309..6793)
                     /gene="galT"
                     /locus_tag="KB913_001868"
     CDS             complement(5309..6793)
                     /gene="galT"
                     /locus_tag="KB913_001868"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBB6820226.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6805..7794)
                     /gene="galE"
                     /locus_tag="KB913_001869"
     CDS             complement(6805..7794)
                     /gene="galE"
                     /locus_tag="KB913_001869"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBB6820227.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            8042..8209
                     /locus_tag="KB913_001870"
     CDS             8042..8209
                     /locus_tag="KB913_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBB6820228.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(8271..10082)
                     /locus_tag="KB913_001871"
     CDS             complement(8271..10082)
                     /locus_tag="KB913_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBB6820229.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(10079..10444)
                     /locus_tag="KB913_001872"
     CDS             complement(10079..10444)
                     /locus_tag="KB913_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBB6820230.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(10607..11002)
                     /locus_tag="KB913_001873"
     CDS             complement(10607..11002)
                     /locus_tag="KB913_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6820231.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(11020..11982)
                     /locus_tag="KB913_001874"
     CDS             complement(11020..11982)
                     /locus_tag="KB913_001874"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBB6820232.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(11982..12194)
                     /locus_tag="KB913_001875"
     CDS             complement(11982..12194)
                     /locus_tag="KB913_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBB6820233.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(12215..12913)
                     /locus_tag="KB913_001876"
     CDS             complement(12215..12913)
                     /locus_tag="KB913_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBB6820234.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(12933..13475)
                     /locus_tag="KB913_001877"
     CDS             complement(12933..13475)
                     /locus_tag="KB913_001877"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBB6820235.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(13607..14611)
                     /locus_tag="KB913_001878"
     CDS             complement(13607..14611)
                     /locus_tag="KB913_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBB6820236.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(14608..15597)
                     /locus_tag="KB913_001879"
     CDS             complement(14608..15597)
                     /locus_tag="KB913_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBB6820237.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(15594..16400)
                     /locus_tag="KB913_001880"
     CDS             complement(15594..16400)
                     /locus_tag="KB913_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820238.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            16566..17522
                     /locus_tag="KB913_001881"
     CDS             16566..17522
                     /locus_tag="KB913_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6820239.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(17599..18117)
                     /locus_tag="KB913_001882"
     CDS             complement(17599..18117)
                     /locus_tag="KB913_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6820240.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(18205..18354)
                     /gene="rpmG"
                     /locus_tag="KB913_001883"
     CDS             complement(18205..18354)
                     /gene="rpmG"
                     /locus_tag="KB913_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6820241.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            18582..19028
                     /locus_tag="KB913_001884"
     CDS             18582..19028
                     /locus_tag="KB913_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBB6820242.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(19223..21118)
                     /gene="asnB"
                     /locus_tag="KB913_001885"
     CDS             complement(19223..21118)
                     /gene="asnB"
                     /locus_tag="KB913_001885"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBB6820243.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         6432 a         4546 c         3693 g         6720 t
ORIGIN      
        1 tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa atatagtgaa caataaggag
       61 aggacttttt aatgcgtgtt aataaaatcg attttcactt ttcaaaactc agatatcaac
      121 ctgattttga acatttctcg gatgaagagt tccaacagat caaggaacat actgttcttc
      181 gttcttataa aaaaggacag atccttttcg acgatggtga tcccagacaa cggttgtata
      241 tcttgaccaa aggactcgtt cgtttagaac gttatgatga aagtgcaact tattactact
      301 atgactatgt gaatacaaat aacctttttc ctatgtcagg aatgtttgga gaagagacct
      361 acacttatac agctcaagcg atgactgata ttgaaacatt ctaccttcct gtttcctact
      421 atgaaaaatt agcacgaaaa aatcccgaac agttgatcta tatgatacaa aaaatttcta
      481 aagtagttga aatacatgaa ttgcgtatcc aaatcggatt gacctctagc gcctttgacc
      541 gggtaaaaca aaatttattc attttgaaag aagaattggg cgtaccaaca aaagatggtc
      601 atatcaccat tccttatccg atcaccttaa aagaattagc agtgaatagc ggcacgacac
      661 gtgaaactgc tggacaagta atcaaacaac tacgtgattc cgggctgtta gattatgaca
      721 aaaagcgttt tactttctgt aagacagcta ctactccagc tatgagagaa taacgcgaac
      781 aaaaataagc agtgaccctg ataaatatca gggtcactgc ttattttcct ccctaaaact
      841 tctgaaagat ccggcagttt tagatcactg gacaagactc aaagattttc tatgtgtgtt
      901 tcagttatgt aatattcact gtttgcaaaa aatactgtta gattaactag atgaagcgtc
      961 ttgtcctcat ccgatctaga ttattcgata ttcctcgaca ataaacgatt actcagtgag
     1021 ggcaatcaga ggaacggata atgataaata agctgtaaaa aatagcaaaa taacaataat
     1081 gattaaaagt atgtaaaaaa tagggctttg acaaaaacgt gtcacagccc tatttcgatt
     1141 aaacggtgtg tacctgtcaa ctcttcggtc acaagtcata atgttcataa acatgaggag
     1201 ctgttttttg aaattgttcc ttgtgaatca gagttaaacg acaggcttac gaactcttga
     1261 ttaaacggcg ttcaaaagct tgcatacgcg gtaataagaa cagccaggtc aaaaacatga
     1321 gaagccgttt ttcctgggct gttcttatta cttgatgcag ggcagctttt tcacaacctc
     1381 tttattcaga taaaaccaag cttggatcag cattcaactg atagctagca aaatttcttt
     1441 tttgcatttc cacatgtgct gctgctccaa tcattgcagc attatctcca caaagtcgaa
     1501 gagggggaat cactagttct acctcaggga gtttagctgc caaagcatcc tgcaatcctt
     1561 cacgcaaccc ttgattggcc gctacacctc cagctataat cagttgcttg actggataat
     1621 tttgacaagc tcgaagtgtt ttagtaatca atacatcgat cacacttgct tgaaagctag
     1681 ctgctaaatc atttttgtct agatcttctc cacgctgttg tgcattatgc accaaattga
     1741 taaatgcact ttttaatccg ctaaaactga aatcataatt atcttcatgg atcatcgctc
     1801 gcggaaaatg gtaattatct tttccctgat gagctagctg atcgatttct tttccgcttg
     1861 ggtaagaaag acctaatact cttccaactt tgtcataagc ttctcctgct gcgtcatctc
     1921 ttgtctcccc aatgatttca tatgatccat cttcttgcat atagactaat tctgtatgtc
     1981 ctccgctaac aagaagtgcc atcaatggaa actggaatgg tttaaccaga cgggctgcat
     2041 agatatgccc tgccatatgg tttacaggaa taagcggcaa ttggtgtgcc caagcaaaag
     2101 ccttagctgc agaaatacca atcagcaacg agccgacaag tcctggtcca taagtgacag
     2161 cgactgccga taaatcttct gccgacacac cagcttctac cagtgcatct tccaagcata
     2221 aggtgatttg ttctacgtga tggcggctag ctacttcagg tactacgcca ccaaaacgtt
     2281 tatgactgtt tatttgagaa gcaacgatgt tagataagat ctctgttcca tttctaacga
     2341 ccgctacact cgtttcatca caacttgatt caatcgccag aatcaattct tcattcattt
     2401 catcgtctcc gtttttaact ttctgctcat aatgatcgca tcttccgtcg gattgcgata
     2461 atatgatttc cgtttaccta atatacgaaa cttttctgat tcataaagtt ttcttgctgc
     2521 ttcattagat agacgtactt ctaaaaaaac atgcagcgaa tcttttattt gttccgtaat
     2581 cagtaattgt aacaaatgcc gtgcatgccc ttttccttgt tctgaaactg caacagcaat
     2641 atttgtgatc tcgacttcat ctattacttt cgagtatcca ataaagccac agatctggtt
     2701 atcttcagct aaaagcagat aatcagagtg aggctgttgg atgtctgcca aaaactgcat
     2761 tttcgtccaa ggtgaaccat gtggataagc attttcgcta atcatccata cgcattctgc
     2821 caagtacgct tcatcaaaat ctttttttct gcaaatcaac taatctcact cattttctaa
     2881 aagttttatc atatccaacg catcttcttt tgtttcagtg taatatcttt ttttgatcgt
     2941 tgttgcttga aaccccaatt tccgataaag tctttgtgca tcttgattac tcatacgcac
     3001 ttctaatgac atcgtctcac agcgattcat tatagcaaag ttctcgattt cgtcaataag
     3061 cagcgaaccg attcgtttac gctgatatgc cggtcgaacg gcaatattcg tgatatggca
     3121 atctaaaccg aacgctcttg aaccgataaa accaatcatt cttccattat caaagatacc
     3181 tagatataga tgaggaagcg gtgacttcaa ttctgatata aaggcacttt ttgtccatgg
     3241 caattcgcca ttatagactt ctcgttcgac atccagcagc tctttgatat cttctgtagt
     3301 caattctctt agtacgtaac gacgatcgat ttgttcgact gttttttctg tataaatcat
     3361 tttatcttga aaaaagcttc tggcatacgc tctaaatttt ttcaacataa ctttcgtctc
     3421 caggtgtgtg cgtctccaac catttttctt ctgcttctac tcgttttaaa tagcgaggaa
     3481 gaaaagcttg tttctctgca actggttcaa ctaaagcacc taattgagcc acagttacac
     3541 cacttggaat atcccatgct ggaactgtat taatcatcgc actaggcaat atttccttta
     3601 tttcagagaa gaatttgtga caatcactcc cgacgaaata aatagcttca ttcagctttt
     3661 gtagttgtgt gaacaaatca gaagcagaaa tatgtacatc ttcaagtaca gtttctaatc
     3721 tattttcttt ccagcggtat gccccagcgt atacattttt tcttcgagca tcaaacatgg
     3781 gcacaataat attatccaca ccgatgcaat tagccgcgat ggttttcaga ctagatactc
     3841 ctactagctc tttatctaat gtataagcaa tcgtttttgc tgtcgttaca cctatacgaa
     3901 gccctgtata agaaccggga ccatcagaaa ccgcgattcg gtcaatgtct tttggactta
     3961 tttgaagatc tgcaaacaat tggtcgattg caggcatcag tgttacactg tggttgcgtt
     4021 tgatatttgt ttgtatttgt ccaagaattt gttcgtcttc taccacaccg atcgccaaag
     4081 tttggtttgc agtatctatt cctaatgtaa tcatatattt gatcctttct gctatgacat
     4141 tctcgccttc cattgtagca tactttttta ttctgaggat gaaaatacca aaggcaaaac
     4201 tagtacaata atacatgatt atctgctggc gggcaaattt tgccccttcc tgaaacacaa
     4261 aaaagctgcg gtatcactcc attttcccac agcttttcca tcttttattt cgttgattct
     4321 cgaataatca actctgtttc cacaataatc tttcttgaaa ccggtgcttt ggaattactt
     4381 aattgaagaa tcgtctccac tgctagctct cccatccatt cggtataaac ttttacagta
     4441 gaaagcgagg gcgttacata tttcgctaca ctgacatcat tgaagcccat cacagaaata
     4501 tcttctggta ccactaaacc tttttcttga atcgctttca gtgcgccaat cgctaatgca
     4561 tcattagctg caaaaagcgc atcaggaaca tgcggattcg tttttaaata ttgcttcact
     4621 gcttgatatc ctgactcgac agaaaaatct gcttcgataa ttggaccttc gtcgtagcct
     4681 ttttctgcca aaacttgttg aaatgccata attctgggat cttttagccg ctgatggttt
     4741 ttcttcgtat attctgttcc agcaagcata gcgatatgtt gcgctttatg ggagacaaag
     4801 tgttcaatga ctttttgaac acttgactta aagtcgacaa ctagagagtc gattccttga
     4861 gaagtgccgt cagaatctac caaaagcaag gcattttggg atcctttcat ttctaataac
     4921 tgagcttcgt cgaattttcc tagtgcgatc gttccatctg ccggaagatc actaatggaa
     4981 tcccacgttt ctttcaataa agtaacgttt gcttcttctg cctttttttc gattcctagg
     5041 cgaatagata aataataaag atcttcaagc tcttccgtat cgtcgtacca ctggatcagg
     5101 cgaagcgttt gcttagtatt tgctgcattt ttacgatgtt tcgtataatt taagcgttct
     5161 gctgcttcaa aaattttttg ctttgtggct aagccaacgg aaagatcagg atcatagttg
     5221 agaactcttg aaacagtagc aggagaaact cctgccaact gcgcaatgtc tttaattgtt
     5281 gccatttgtc tctcctcctt ttttacgttt ataaaatcgc agtaaatcgt tcaaacgctg
     5341 cctgtccttt ttcatctcgc ttgaatactc cagcgtcttc cagtacacgt gcaaaaacct
     5401 gacctacaga tttttgtacg acatcggtga ccgtatcttt cgtcaaatca ggatgttctt
     5461 tttttaattg ttctgcccac ggacgatgat attcagccat ctggttttct tctcctaata
     5521 agaaatgctc tacttctact agttctggtt tcaaacgagg tggtaaaaca gcaagcccca
     5581 ttacttcgat caacccaatg ttctcctttt tgatatgttg gacatcttta tgtggatgaa
     5641 aaatcccatc aggatgttct tctgaaacat tgttgtctcg aaggacaagg tccaactcaa
     5701 agtaattgtc ccttcttcgt gcaattggcg taatcgtatg gtgtggtgta ccatctgctg
     5761 aaaaagctct gatagatact gtttcatccg aatatgcttt ccatttttcc aatactgagt
     5821 tagctgcttc aataagcaag tttttctctg ttgattgcaa acggatcaca gacatcggcc
     5881 atttcacgac tcctgcgatg acttgcggat aatcttctag tttgataagt ttttctatcg
     5941 gtgcttttgc cataggaaat tcatgacgtc ctgcctgata atgatcatga gaaagaatcg
     6001 atcctccaac aattggtaag tcagcattcg aaccaacaaa gtaatgaggc aagacttcag
     6061 taatccgaag cagtctagca aatgtttcct ttgtgatttt catcgggcgg tgttgttctg
     6121 ataaaatgat cgaatgttca ttgtaataag cataagggga atattggaat ccccagcttt
     6181 caccgtctag attcattcga ataatccggt gattggtgcg ggctggatag ttcaagcgac
     6241 ctctatatcc ttcgttttcc atgcaaagca tgcaggtagg atagtctact tttaccgcct
     6301 cgcgttctgc tgcgatttgt tttggatctt tttctggctt agataaattg attgtgattt
     6361 ccagttcacc atactccgac tctgccggaa atttgatgtt ttttgcgatg gctcttgttt
     6421 tgatgtagtc atttttctta cttaaattaa agaaatactc agttgcttcc tctgggcttt
     6481 tcgaatagtg ctgtgcaaag aatgcattga cgactgaagg tggcggtgtg agaaaatcca
     6541 ttaattgcgc ttcaaaaatc tcttgttctg ctggcaattc tgaaagaaca ccattttctc
     6601 ttgccttagc gacaagctga tccaataagt ctacagattc ttccttaact ggtcttactt
     6661 caatgctttc tagagcatct tctcctacca tccctaaaag acgattctgt aaatataagc
     6721 ggtccatttc catccatccg ccagcttcga tcgcaagtgt ggcaaaatca caaatcgttt
     6781 gactgattga catatctcat tcccctattc ttcataacca tttggatggc tgacatgcca
     6841 atcccatgct gttttgataa tcgctttgat atctgtgtat tcaggtttcc agcccagaat
     6901 ctctctcgct ttttcacttg aagcgactaa tcggctagga tctccagctc ttcttggtgc
     6961 tatttctgct ggaatttctt ttcctgtcac ttctctagct gcttctagca tttccttgac
     7021 tgagtatcct ttgctgctgc ctaaattgaa gaagttgctt tcatttcctt ctttcaagta
     7081 ttccaaagct aaaatatgtg cagcaatcaa atcttctact tgaacataat ctctgataca
     7141 tgttccatct ggtgtatcat aatcgtctcc ataaacagcc aaggcttttc tttgaccaag
     7201 agctacttgt aaaatgattg ggacaagatg cgtttctggt gtatgatctt ctccgataga
     7261 tgcatctgct tttgctccgg ctacattgaa gtagcgcaaa gcgacatagc gcatgccata
     7321 tgcttggtca caccacttca tcattttttc catcatcaat ttactttcac catacggatt
     7381 tttaggatta gctggtgtat cttctgtgat tggagactct ttcggctctc cataagttgc
     7441 tgcagtagaa gagaatacga ttttattcac gttgaactcg tgcatgactt caagtaagat
     7501 ttgcataccg tatacgttgt tgttgaaata catcaatggt ttttcgacag attctcctac
     7561 taaagagctt gcagcaaaat ggattactcc ttcaatcggt tccttttcaa atacggaacg
     7621 tagaaattct ttatcccgga tgtctccttc ataaaaatga gcatctggat gtactgcttg
     7681 tttgtgacct gtgagcaaat tatctaccac agctacttga tacccctttt gaactagctg
     7741 gtctacagcg tgcgaaccga tataaccggc tccgcctagt actaaaattg tcataaaaaa
     7801 cactcctttg attagtaaaa ttgtgtttgt tgattctata taatttaaaa aacgaagttt
     7861 acttttatgg tgaaaacaaa caaagtaaaa tttcgtaaat tcatatggta aatttataat
     7921 aaaacattta gtaaacattt tcaagggttt tttgcaaagg tttacaaaca aacgtaaaac
     7981 tagccttttt ttctcttttg ttccataata gatataacaa ataataaatg aggtggattc
     8041 aatgaaaaaa tttgtatctg gaatattagt aggaagtctg gcaacagccg ctgccgttgc
     8101 tggtttggtt gcttctgtga aaaaaacagt gatcgatcca attgacgaaa aagaagcaat
     8161 gatcgaagaa aaccgtaaaa aagcaatgcg taaacgcgtt tctcgttaat aattatttaa
     8221 aaatacgcat gaagactttc taaaaaacag ataagtcatc atgcgtattt ttatttgtca
     8281 gtcaatataa gttgtgctat tttatctgcc tgtctcagat tccatggatc tgtataaggt
     8341 ctagctactg ctgcagttag ccaatccaca ccttcaacag gtattccata gcaataaaag
     8401 tcagactgga tttcccctga agcatcaatc acgcgattcg tacctcgctc aacatctata
     8461 gcttctgaat gataacttcc tgtattatct gaaaatgaaa aagggcgaac aagtttgttt
     8521 tccttcaaat tttttatgac aggattactt gaacgagaaa agcttgtttg tggcaatcga
     8581 gcttcaatca aatagcgact gctgatttct ttatcttgta gagaaataac atagcggttg
     8641 tgcttttgct gaatatcaaa tggcggttcg atcaaatgaa aaatacccgc atctatcagt
     8701 gctgctaatt ctttcgtccg aatgattggc ggaccgatcg ttaaaaagct atttagatga
     8761 gtaaaccatc cccatagtat ttctttgtat tccttagcag aaaaaacgtg ccattcaata
     8821 gcctgccgga ttggatcacg ccagtctttt aatgcatcaa atgttgaagc aaatgctcct
     8881 gtgcaattgc ctttttccgc ttcttttatc tgcccttcaa taaatattcg gctagcttct
     8941 gaaaagggct cattctgata ggcaagagga gtttctaaat acgaccaatc ccatctataa
     9001 gggattagtg ctggatgctt tccgagacac tcctctgaag agagggagag aaaatcatgc
     9061 tcaaaatttt tctttggaat cggcaagtga tattcttcga tgattttctt gtaataaaac
     9121 aactcaacgt cttttttcag atagtcaaaa aatgtttcgc cagtcaaaaa tcccgactga
     9181 tgccattgct ccaggttttc ttttgttagt aaccgtggcc atgccattgc tccgccttgc
     9241 ttttgatttc ttcctcgagg gtaataaggg agcccccttc ttgatccact gtatacaatc
     9301 ggttccttgc ctgatggatg atagaccagt tttccctttt cgttctcgaa gcgccctcct
     9361 cttgatactg taaacaatcc gacataatca aaaaaactta agcctagacc tcttaaaaag
     9421 acattttctt taggcggtat cttcgaaaga tctacatctg caggattaga aggaagctga
     9481 tacagtaaaa catttttctt tgcgtagtct acccacactc tttcttcttc tgtctcatca
     9541 ttttcccagt gaccgcttgc taaaacaagc tgatcgatag aatagctttg ctgatctgtc
     9601 tgtaaaagat aaccatcttt tcttttgctt acttttttta ctaaagaata aacaaactga
     9661 atagaagctg gaaattcttc ttgcaacttt gagaaaaacc agcgttgata gagtccgtat
     9721 aaacatcgag tagattgctg atctttttcc agacgattga tttcttctat aattagttgc
     9781 ttatttttgg ttaccgtctg ttcgatataa tctgtagcag gtcctttact ccattgaaac
     9841 aagttgggtc cctgtgttac caatcctcca ctggacaatg tttcatctgt aaaaagcgtc
     9901 acttgttgag aaacagaatt cattaataac tccggtggct gattcaaccg ccaaactcga
     9961 cctccaggac cattgggatc gaaaagaaaa agttcaagag aatgtctgtc ctgattatta
    10021 tggagaatcc tttctgctac acttaatcct ctaggtccgg caccaatgat ccctattttc
    10081 atttgcatgc ctccatttcg ataaattttt tcaataaaac agcatggttc tgatgttcat
    10141 tttttgcacc ataaacaaaa gtaatgactg gatgttcttt cataagttga ctgagtttaa
    10201 aaatagcttg cttcttttct tcttcgaaaa tcaattcttg ctggtatttc tttgcaaatg
    10261 aagcaaatcg ttctggtaca tggtcaaaag ttttgcgtgc ttcattacta ggtgcaattt
    10321 ctttcaacca cagatctaac tgcgcttttt cttttgaaat tcctcgtggc cagaatctat
    10381 ccacgagtat tctatagcca tcctcttttt cagcatcaag gtaaacacgt tttaatttga
    10441 tcatagttgt ttccttcttt ctaccttttc gcttagctta tatatgtaga taatagcaca
    10501 aaataaaaaa aatgaacggc acaactatcc attgcgccgt tcatgtgatc ttggtcaaaa
    10561 tctaatgatt gattcggttt ttaaagctgt catacaatca tctgttttat acttttttac
    10621 ttttgatttt tccagaccat ccgtcatatc cacccttaag taaataaatc tcttgataac
    10681 ctgctttacg taatttattt gctgtacgga tgctcaaact tttcttttga tcgtaaatat
    10741 agacaggctg gtcttttcga atagatccta atgaatcttt caaaacagtg taagggatgt
    10801 ttcttgcacc taaaatatgc ccagcatcaa acacatcttt ttcgcgaaca tcgattactt
    10861 gtgcttttct cattccttct cgaaattctt cttctgtcaa agtcgttgct gaacgtttgg
    10921 ccattactcg tagatagact tcccaaagga tgattgcaag cacaatcaat agcaaaatga
    10981 tattaattac ccataaaacc atgtaatgcc tccgtttttt taagcaaatt tcaaggctaa
    11041 tgaggcagca ccaatgacac cagcttcatt accaagctct gctaatttga tttttgttga
    11101 ttctcttact tgcgggaaag taaattcttt aaaatatttc tctacacggc tacgtaaaaa
    11161 ttctcctgct gccgatactc ctccacctaa cacgatactt gacggattta atgtattccc
    11221 caagtttccg caagctaaac ctaagtagaa gcatacgcga tcaacaacca tcaatgcaaa
    11281 cggatcgtct tcttgagcca tttcaaagat atctttactt gttacttctt ctccgttgtc
    11341 tagcattgct ttcagttttg aatcccctgc gtattcttct gccaagaaac gacctaggcg
    11401 taccacacct gtagcgctag atacagtttc taaacatccg cgtttaccgc aagtacattc
    11461 gaacccttca ggatccacag tgatatgtcc gatttctcct ccagctccgc tcacgccgtg
    11521 aatcaaattt ccgccagcaa cgatacctcc gccaacacct gttcctagag taacgaatac
    11581 aacgtctgga tcgttttctc cagcaccttt ccatcgttca cctaaagcag caacattcgc
    11641 gtcattatcg atagcgaatt tgattcctgt tcctgcctcg atcagttttt tcacaaattg
    11701 aacttctgtc cagtttaagt tatacgcacc aataaccgtt ccagcttcgc tgtccacgct
    11761 tcctggggta cccatgccga ttccgataaa gtcttcggct ttcatattat ataaattcaa
    11821 acgatgattg attgattcaa tgatttcagg aacgatatgc ttaccatcat ccaaaatatt
    11881 ggtatcgatg ctccattttt gctgaatctc tccttctggt gttaaaattg caaattttgc
    11941 tgttgttcca cctaaatcaa tcccaataat cttcttgtcc attacaaatt tcctttcttt
    12001 cggctttctt caattcggtg ctctcttttt aatatgcgcc acgctgtcat gtatgtatca
    12061 tgatcaatca aacggctatc atacagatta cgcaattcga tagtcattaa ttcaatgtca
    12121 tagatgcgtg cacccacata gataaagatg ccaaattttt tgaacagctg ctgtacatca
    12181 tataagctct ccatctttaa gcacttcctt catattatac aagtaaacca tattttttta
    12241 aacccagtaa aatacatatt acaaaaagaa atacaaaaac tagtgtagaa agaatccttt
    12301 ggtgtatcga atagcttgtc tgttgtttcg gtagacccaa aacattccct aacactaatc
    12361 cgccaattag cccaccgaca tgtccccaaa catctacaga ggtatccaga agaccaaaaa
    12421 caaatgtcaa cacaataaat aaaagaaaat gtctgactag ctgctggatc gctgggttat
    12481 gtttaaaatg aaaccctaag ataaacaacg caccgaacaa accgaatatc gaagtacttg
    12541 caccaccaga cagaacattc gcttcgttaa aagcaaagct tgctgtattt cccattatcc
    12601 cgctgaacat ataaatcaag aaaaaacgcc aatggccata gattgcctcg atttgctgcc
    12661 ccataaaata cagtatcagt gagttcatta cgaaatgcat cagtccaaaa tggatgaaga
    12721 ttggtgtcac taaacgccac cattcattga agtgaacaag ataaggacca tacattccgg
    12781 cataataagg gatctcaagt cgcggaaata attccatcat gaggaagacc gctgtctgta
    12841 tccctaaaaa agcataggtc cataacggtc gtcttaacca tgcacgcaat tttatttgct
    12901 gttgataatt catgaaaacc tcccatttca ttttagtcaa taaacaattg ttggatcttc
    12961 tgatcaaagc tctccggttg ccattgttca ttcaattgtt cacgaaaaac aaggctacat
    13021 gtttttttat gaaaattatt taaataccgg tcgtaataac caccgccaaa accgattcga
    13081 taaccggctc tattgtagat aatacctggt acaatgagga gatcgatcat ctccggcaaa
    13141 tagagcttct ctgattgtgg ctcaagaaca ccaaaactcg aacgtacaag aacggactgt
    13201 tcatccattt cataaaacgc catctgacgt ttcggcaaag ttttaggtac aactattttc
    13261 ttttgttctt tttctgctcg ttggataacc ggctgtgtat ccagttcaaa ttcattcgat
    13321 aaagtcgtcc ctatcacttt tgctgacttc cagtactcgc tggcgaatag ctgtttatag
    13381 attcgctgtt ctttttcctt tttcttgcca cttttggcca gatttttcag cttttcgatt
    13441 cctttccggc gtaatcttac tttcaattgg tccaaaaact cacccttcct tctctcataa
    13501 aatggtatag gaaaaaaaga aaaatagcaa tcgaactttc aaataaatgc ataaatagaa
    13561 taaaaagaag acctagaaat gattggcctt ccttttttaa tgaatttcaa ctgttcagcg
    13621 cgtgtttttg tctgataaaa agtgcataca gaaaatatgg cgcaccaaaa agggcaatca
    13681 aaattcctgt aggtacttcc ccacttggta gaatcactct agcaaccata tctgcactaa
    13741 gcagaaaaat ggaaccgaac aaaccgctca gaacaaaggt ccagttattt tctttacgta
    13801 cgactagctt cgcagcatga ggagctagta gtcctacaaa agataaacta cctgtcaccg
    13861 ctacactacc gcttgccaaa gcaacagcta acaacaaaag gattttttga cttttagcca
    13921 cgttaaggcc taatccttgc gcgcgttctt gaccaaatga tagcaataca atcctctgtg
    13981 cataaagtcc tcctagcgga attaagataa ccgcccatgg aagcaatgcc caaacataag
    14041 gccagctcgc accccagatt gatcccgcta accatgcatt cacaaatcca taattttcct
    14101 tagataattg gatcgtgcat agcaatgtta atgcagaaag gccggcatta acggcaatac
    14161 cggacaataa gattcgattc atacccaaaa agccatttcg atcataggcc gcaagataga
    14221 cacagcaagc agctaaaaca ccacctagaa aggctacaac tagcaataga aacggcagcg
    14281 aatagtgcga aaagaaacct aaataaagca tcactaaaaa tcctgctccg gcattaatgc
    14341 ccaatatact agaatctgcc aattcatttc ttgttactcc ttgcaagata taaccagaaa
    14401 cgccaagaca agctcctgct aataaactga tcagtaatcg aggaactcga aattctctaa
    14461 caatcagcgc caaagaagat gattctttcc ctatgaacgt ggcaaaaagc tgatccaggt
    14521 aaataaaagg cgtaccaatc attaaactac ctatagacag gatgacaagt acaaaaagca
    14581 agaaatagaa cgtccaatat atttttttca ccgttgttcc ctccttactt gtatcagtaa
    14641 aaacggaacg ccaatcaatg caatgactaa tccaaaaggt gtttcaaaag ggggattgat
    14701 catcctcgct gtaaaatccg ccaacataac caatccaccg ccaactaaaa aagagacagg
    14761 tagaacataa cgatagtccg ttccaaccat tccgcgaaca actggcggaa ccaacagccc
    14821 aataaatgaa acaggtccga ctaacgaaac ggcaatggct gctaacactg caactagaca
    14881 gaaaacaatc aaccgcgttc gtttaggatg acttccaaga gctaatgcat gtgtttcact
    14941 caaatgaatc aaagatattg cttttcctaa tgaaaaagaa accaaaacag caagtatata
    15001 taaaggaaac aatactgcta attgtttcca tgtgatattg gcagctccgc ctacaaacca
    15061 aaaagcaaga tcctgctgca gattaaagaa ttgggtaagt gcttggctga tagcagtaaa
    15121 aaaagaacta atagctacgc cagctaaaat cagctgtaaa ggattcatgc ccattttcga
    15181 aaactgcaaa aaaccaaata cgagcaaagt tacagcaaaa gaacctgcca atgacattag
    15241 aaacacagaa aaatcagaag ctttaggcca aaaagcaaaa ctaagggcca ttgccaacga
    15301 agcacccgcg ttgattccta gtaagcctga atctgctaaa ggatttcttg tcactccttg
    15361 catcaatgca ccgctcaatg caaaacaact ccctacaaga aatgctcccg ccacacgagg
    15421 caaacgaata tttcgtatga tttggtgact ttgttttgat ctatcaaaat caaacaacgc
    15481 ctgccaaaaa tctgcttttt ccacagtcgc tgcgccattt gaaagagcaa caaaaaaaat
    15541 aatcaaaaga acaaaacaga ccaaaagcag gagtctattt ttcttcatag tcctcataat
    15601 tgatcctcct gctcttttgg caacaaatca taggttagaa aaactggttt atttgttctt
    15661 ggaagcgtga caatcgttgc atcaatctca aatatttttt tcatacactc ttttgtgatc
    15721 acttcttcag gtgtaccttc tgtgatcaac ttaccgtttt tcattgctaa taaataatct
    15781 gaaaaacgtg aagcatgatt aatgtcatga atcgacatca agatcgttgt ttgtttcatt
    15841 tgattgattt cagtcaataa ctgtaggatc tctaattggt gtgccggatc taaaaatgtt
    15901 gtcggttcat ccaagatcaa gatatctgtt tcctgagcaa gcgccatagc gatccagaca
    15961 cgctgggttt gtccaccaga cagcgttgcg atatcccgca tacgaaatcc agctagacct
    16021 gtagcatcca acgcccactc aattgcttca tgatcttgcg tgtccatgcc actgaacagt
    16081 ttttgataag ggtatcgtcc gtaagatact acttcttcta ctgtcatacc tgtagggtgt
    16141 tcactagttt gtgctaataa tgcaattttt tttgcaagtt cttttgaact gtatgtagag
    16201 atatcagagt tattgacaat gatctttcct gatttcacag gtagtatacg ggtaaaactt
    16261 ttcaataaag tagattttcc acttccattt ggcccaatca aactagtgat tttcccttca
    16321 ggaatcgtaa cagacatgtt ttcaatgatt tttttgtttt cgtagccggc tgcaatgtca
    16381 gctgctctta atctcgtcat ttcacccatc ctttcgctga aaatcattct caattatgac
    16441 gctgtttcaa catttcgtca agcgctactt tcatatctat agccaaatga agcggttgac
    16501 agcgttcgaa atatcaggaa taataaccaa tgagaaagat tctcaattat gttaggagga
    16561 aagaaatgaa attaaaaaca aaagtattca cattatctag catattgctg ctggctggag
    16621 tactgagcgc ttgctccccc tcttcagata aagaaacagc tacaactgcc aattcgacga
    16681 cttcatccaa tagtactcat acagtcacag atacacttgg acataaagta gagattccaa
    16741 acgcgcccaa acggatcatc ggcagttact tagaagacta tctgattgca ctaggggaaa
    16801 aacctatcgc ccagtggact gttggcagtg gttccattca agattatctg caagatgatt
    16861 taaaggatgt cccaacgatt tcttatgacc ttccttatga gaaagtgtta agctttgagc
    16921 ctgatttgct gttgatttct tcttccgcta ctgtcgaagg cgggaaatac gaacaatata
    16981 gcaaaatcgc gccaacttat gttgtaaaaa acggaacaga tgtcacatgg gaagaacaac
    17041 taaaagatgt cggcaaagct ttggcaaaag aaaaagaggc agaaaaaatc atttccgatt
    17101 atcaaaaatc catcaagaaa actcgagaag aactagcaga taaaatcgag aacaagacag
    17161 ctgcagtgtt gtgggtgacc aacaactcag cctttatggt cagcaaaaat cggtcaagtg
    17221 gaagaatcgt atacgacgat ctggaatttg gtgttcctga tctagtggaa gaggtctcca
    17281 aaaaagccac ttctgactgg tctgctgttt cctctgaaaa gctagctgaa ttagatgctg
    17341 actacatcat ccttgtgaac agtgacaaag atgctgccat gttcaatgaa ccaagctgga
    17401 agaatctaaa agcagtgaca gacaatcatg tactgcaatt cggacctgaa tctagttggc
    17461 tatataacgg acctattgcc agtcaggaaa tggtcaatga tatcaaagaa aaactaaatt
    17521 gattttaact aaaaaaagca tcttcacgat tagtcgtgag atgctttttt tcttattaac
    17581 aaactagacg catagatttt attcttcttt tgaagcaacc ctatttttta ctctttccca
    17641 tttttgaaaa cgatgggcat atagattttc ttgatccgtt atcccctcat actcctctat
    17701 aagggcgaag tctgaaaaat caatattccc aatatacgta tcgccttcaa acgtgctatc
    17761 gatcaatgtt cgccagatcc gaccagtgta aggaagaagt tcttgaaaaa tccgactacc
    17821 acccgaaaca tagatatctt ctgagatcgt ttgactatac gacaaaagtt catcgatcga
    17881 atgcattact tccgcatttt ctttcgtgcg aaaatttggt tgcgttgtca acacgatgat
    17941 atggcgataa ggaagtgaaa gatcccccat tccttcatag gtctttcttc ccatcactaa
    18001 aattcgatcc attgtatgtt cgcgaaagaa acgcatatca tttggcaatc gccatggtaa
    18061 caaaccattt ttgccgatca gaccattttt atcttgtgcc cacatggaaa taaacatatt
    18121 atccgctcct tatgatttta gatgttttga gataaaaaaa gtctcaattc tttgaccagc
    18181 aaggaattga gaactttaaa aacattattt tgtttcacgg tgcaaagtaa ctttgcgttc
    18241 gcgtgggcaa tatttttgtt tttccaaacg atcaggattg ttacgtttgt ttttgcttgt
    18301 tagatagtta cgttctttac aagaagtaca ctctaaagtg atgtttacgc gcatgttttt
    18361 ccctcccatt tttacaagaa tcctctaaga tgactctcag acttgattat cttaccatga
    18421 ttttttctag attgctagtg tttttcacga ttttgttaag taaaactact tgacgataaa
    18481 tacaacggtt ttacttctca aacaaaatct ttttcttttt gtataaatac ccttacactt
    18541 gtttatatag attatgtttt ttaataaagg gggatactaa tatgccatgg aacatgaagg
    18601 actttcctgc atcaatgaaa aacttagata aattgacaag aaaaaaagca atcgacatcg
    18661 caaatgcatt attagatgaa gggtaccctg ataaccgtgc gatcccaatt gccattgatc
    18721 aagcaaaaaa atggtatgaa gatgctagtg aatcagaaaa acgaactttc gaaaaagaaa
    18781 aaaatccaag caagacggat gaacacgata cgaatcctcg tgctggaaaa ctgcttgatt
    18841 cagatgtgat cgtagaatat gaggaagaac aatggatcgt gaaatctaaa ggggcaaaaa
    18901 aggcaagcaa ccattttgat acaaaaaaag aagcaatcga aaaaggaaag caagtagcac
    18961 aaaacaaaga atcaactttg ttcatttata aaaaagatgg gacaaaagaa aaagaaatcg
    19021 attattgaac atatgtaaag gggttgtgac gaaaatcgtg tcacaacccc cttatgttcg
    19081 aaacaatggt gttcctctgc caactccgaa ccataagtca taatatctat aaaacgggaa
    19141 gagctgtttt ttgaaattgt ttcttatcac tcagtgttaa acggtaggag aaaacctctt
    19201 ttttattgat atttgatttt catcaaacag tcacatagtc gattgcttct gcttgcggaa
    19261 tcgtttcatc tacaaagtag actttatacc atgtcaagaa actgaagatt gtccagattt
    19321 ttctttgctc ttctttacgt ccttcgtgat ggtcatctag caacttcatg attttttctt
    19381 gatcaaaaaa ttcttttgca aaatctgctt cgaataatgc tttgacttgt tcgtagccgt
    19441 gttcttcttt caaccaagct ttgattggca cagggaatcc taatttcaca cgattcgacc
    19501 attcttccgg aagatgtttg ttcgcagctt gtctgaaaat atcttttgtg ttgttttgat
    19561 tcaataaaaa cttacttggt atttgttgag ccaatttcat gacttcgata tccaataaag
    19621 gtactcggac ttccaaagaa cttgccatag aaagtttatc tgcctttaac aagatatctt
    19681 ttggcatcca ttgatgaaga tcgacatatt gcatcttatt gacttcatct ttgattcctt
    19741 ctgttttctc gtaatgaaca gtcatgattt catccacaga tggtgctgtt tgatattttg
    19801 gtgttaacac ttctgatgct tctgattctt cgaacactcg agcatgaccg ataaaatatt
    19861 cttttgcagg agcaagtgat tcatataaat ggatccgtcc atggaagttt ttcatttttc
    19921 cgattttacg tcctaaatta tagcgtgttc cttttggtaa ttttttcaat ccttgagcaa
    19981 tcacacggat gaattttgaa ttcgtatgga atccatacgt ttggtatccc gcaaacagtt
    20041 catccgcccc ttctccagat tggactaccc gcacactttg tgaagcaaga tttgctaaaa
    20101 agtacaaagg tacgcaagaa ggatttgaat caggttcatc taagtgatac tggatcaaag
    20161 ggaatgcttt gaacgacatg tctccgtcga tcactgctgc tgtattatct aagtccaata
    20221 gttcggttag ttttctggct tcaatcgctt cattataggt tttatcatca aacccgattg
    20281 agaaagaatg atctggtttc aatacagagg ttacataact ggaatcaacc ccgctggata
    20341 agaaagaacc aacttctaca tcactgaccg tatgtgcttc aatagaagct tgaacggttt
    20401 cgtcgatttt ttcgatccat tcttgtcggg aatgcgtttc ttttgtttca aaatctgcat
    20461 cccaatattg ctgaatgtct atttttccat ctttatacgt ataataatgg ccttcaggca
    20521 aacgatagac atctttgaag aatgtttcgc cgtttaatgg agaatattgg aaagtcatat
    20581 aaggtttcaa cgcttctttg ttcaattctt tgttaaaatc aggatgaggc agaaaacttt
    20641 tgatttctga accaaacata aatgttccgt tcatttctgc ataataatat ggtttgatcc
    20701 caaagtggtc tcttgcaccg aataactcat tcttttcatt atcccaaata gcaaaagcaa
    20761 acattccgcg gatcttttgc aataattctg ttccccattc ttcgtaacca tgcaaaagga
    20821 cttctgtatc tgcatgtgtt tgaaaaacgt ggccagctgc aatcaattct tctctcaaag
    20881 gctggtaatt atagatttcg ccattaaaaa taatgatctt tgtccgatct tcattgtaaa
    20941 taggctgagt accgccctct aagtcaataa tacttaatct tctgaatcct aaagcaacat
    21001 gtttatcgat atattctcct gaactattag gtccacggtg aacgattcga tccatcattg
    21061 tattaataat tgtttttttg ttgtccttgt cgttaacaaa acctacaata ccgcacattt
    21121 aactttcaca tcctaatata aaattactgt ttatttcatt catatgcatc ttatcataga
    21181 ataaatagcg gacgaatatt ttctctctta caatttcgtc acgtgaaaac aaaagatgaa
    21241 agtttctgtt tttacagaaa ataaagtccc aatatctaat ttaccatgtt ttcttttttg
    21301 aggctacctt attctcttcg tgttaaaaaa atattagtgg atgctatttc caaaaaaacc
    21361 agcaaaaaaa gacacgacct aaagatcgtg t
//
LOCUS       DADVXE010000047        20886 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.048, whole genome shotgun sequence.
ACCESSION   DADVXE010000047 DADVXE010000000
VERSION     DADVXE010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.048"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            112..306
                     /locus_tag="KB913_001886"
     CDS             112..306
                     /locus_tag="KB913_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820244.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            575..874
                     /locus_tag="KB913_001887"
     CDS             575..874
                     /locus_tag="KB913_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820245.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(971..1405)
                     /locus_tag="KB913_001888"
     CDS             complement(971..1405)
                     /locus_tag="KB913_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6820246.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1637..2347)
                     /locus_tag="KB913_001889"
     CDS             complement(1637..2347)
                     /locus_tag="KB913_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBB6820247.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2337..3197)
                     /locus_tag="KB913_001890"
     CDS             complement(2337..3197)
                     /locus_tag="KB913_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBB6820248.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3202..3840)
                     /locus_tag="KB913_001891"
     CDS             complement(3202..3840)
                     /locus_tag="KB913_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBB6820249.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3855..4154)
                     /locus_tag="KB913_001892"
     CDS             complement(3855..4154)
                     /locus_tag="KB913_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6820250.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4197..5681)
                     /locus_tag="KB913_001893"
     CDS             complement(4197..5681)
                     /locus_tag="KB913_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBB6820251.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5701..6162)
                     /locus_tag="KB913_001894"
     CDS             complement(5701..6162)
                     /locus_tag="KB913_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6820252.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="KB913_001895"
     CDS             complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="KB913_001895"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBB6820253.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7465..8235
                     /locus_tag="KB913_001896"
     CDS             7465..8235
                     /locus_tag="KB913_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6820254.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8508..9335)
                     /locus_tag="KB913_001897"
     CDS             complement(8508..9335)
                     /locus_tag="KB913_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6820255.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9903..11138
                     /locus_tag="KB913_001898"
     CDS             9903..11138
                     /locus_tag="KB913_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBB6820256.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12137..12397)
                     /locus_tag="KB913_001899"
     CDS             complement(12137..12397)
                     /locus_tag="KB913_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBB6820257.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12424..13725)
                     /locus_tag="KB913_001900"
     CDS             complement(12424..13725)
                     /locus_tag="KB913_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6820258.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14017..14475)
                     /locus_tag="KB913_001901"
     CDS             complement(14017..14475)
                     /locus_tag="KB913_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6820259.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14488..15819)
                     /locus_tag="KB913_001902"
     CDS             complement(14488..15819)
                     /locus_tag="KB913_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBB6820260.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15830..17272)
                     /locus_tag="KB913_001903"
     CDS             complement(15830..17272)
                     /locus_tag="KB913_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6820261.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17259..18023)
                     /locus_tag="KB913_001904"
     CDS             complement(17259..18023)
                     /locus_tag="KB913_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBB6820262.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18127..19002)
                     /locus_tag="KB913_001905"
     CDS             complement(18127..19002)
                     /locus_tag="KB913_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6820263.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19257..19341)
                     /locus_tag="KB913_001906"
     tRNA            complement(19257..19341)
                     /locus_tag="KB913_001906"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19305..19307),aa:Leu,seq:caa)
     gene            complement(19359..19430)
                     /locus_tag="KB913_001907"
     tRNA            complement(19359..19430)
                     /locus_tag="KB913_001907"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19396..19398),aa:Gln,seq:ttg)
     gene            complement(19440..19512)
                     /locus_tag="KB913_001908"
     tRNA            complement(19440..19512)
                     /locus_tag="KB913_001908"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19477..19479),aa:His,seq:gtg)
     gene            complement(19574..19658)
                     /locus_tag="KB913_001909"
     tRNA            complement(19574..19658)
                     /locus_tag="KB913_001909"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19622..19624),aa:Leu,seq:caa)
     gene            complement(19679..19749)
                     /locus_tag="KB913_001910"
     tRNA            complement(19679..19749)
                     /locus_tag="KB913_001910"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19715..19717),aa:Cys,seq:gca)
     gene            complement(19795..19866)
                     /locus_tag="KB913_001911"
     tRNA            complement(19795..19866)
                     /locus_tag="KB913_001911"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19832..19834),aa:Gln,seq:ttg)
     gene            complement(19878..19950)
                     /locus_tag="KB913_001912"
     tRNA            complement(19878..19950)
                     /locus_tag="KB913_001912"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19915..19917),aa:His,seq:gtg)
     gene            complement(19953..20026)
                     /locus_tag="KB913_001913"
     tRNA            complement(19953..20026)
                     /locus_tag="KB913_001913"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19992..19994),aa:Trp,seq:cca)
     gene            complement(20033..20113)
                     /locus_tag="KB913_001914"
     tRNA            complement(20033..20113)
                     /locus_tag="KB913_001914"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20077..20079),aa:Tyr,seq:gta)
     gene            complement(20115..20190)
                     /locus_tag="KB913_001915"
     tRNA            complement(20115..20190)
                     /locus_tag="KB913_001915"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20155..20157),aa:Phe,seq:gaa)
     gene            complement(20226..20298)
                     /locus_tag="KB913_001916"
     tRNA            complement(20226..20298)
                     /locus_tag="KB913_001916"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20263..20265),aa:Asp,seq:gtc)
     gene            complement(20308..20380)
                     /locus_tag="KB913_001917"
     tRNA            complement(20308..20380)
                     /locus_tag="KB913_001917"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20345..20347),aa:Val,seq:tac)
     gene            complement(20396..20467)
                     /locus_tag="KB913_001918"
     tRNA            complement(20396..20467)
                     /locus_tag="KB913_001918"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20432..20434),aa:Glu,seq:ttc)
     gene            complement(20482..20571)
                     /locus_tag="KB913_001919"
     tRNA            complement(20482..20571)
                     /locus_tag="KB913_001919"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20535..20537),aa:Ser,seq:gga)
     gene            complement(20611..20684)
                     /locus_tag="KB913_001920"
     tRNA            complement(20611..20684)
                     /locus_tag="KB913_001920"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20648..20650),aa:Asn,seq:gtt)
     gene            complement(20694..20809)
                     /gene="rrf"
                     /locus_tag="KB913_001921"
     rRNA            complement(20694..20809)
                     /gene="rrf"
                     /locus_tag="KB913_001921"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6580 a         4385 c         3325 g         6596 t
ORIGIN      
        1 aaaactttca aattgattct ttttatttat cataaagata tagatacata atcattttca
       61 cttacatata tttgaatatt aactaaaaac agcaagaaag aagaggatca aatgtattat
      121 gtagaagtaa aaacaaaagg cgtcaaaaac aaacaatatg tgaaaggtat cagtaacgaa
      181 tatcctttac ttggttcatg gaaagaagct gctccttttt ccaaaccatg tgccataaaa
      241 ataaagaacg agctagaaaa agaactgact tgtggtaaag ctgttgtaga tatcatcgaa
      301 aagtaaatcc aatgtataga aaggaagatc acacatgaaa agcgacgtac aaattgctaa
      361 gattatagaa ttagaagaag aagacgcagt gttgacaatt gaaaaaaaat aaatgtttgt
      421 ataccatatg attatttcaa tatgtatcct ggaattggag atctcgtaga gctatatcaa
      481 gatgaatcaa atatacttgt cattcatcat gaaatataga gacttataaa attgtttatt
      541 tttataatgt atcagtatag aaaggaaata aaacatggat tatactgttg aatttgacag
      601 tgaactactt aagcaatttc cacaagaaga acatttcatg tataaagaag caatttccca
      661 caaagtgaca gagtatttgg agcataattt ttttcgtata aagccagtgc gtactcgttc
      721 ggcaaaagga atatacgaga tgaaagtcaa aattaataaa aaaaattatc gcatagcatt
      781 tgctttaaaa aaaaatcatg tgttcatttt ttatattagt tcgaatttgc aaaaaattgt
      841 atttgataaa gaggtgagta aaaaaataaa atagctgagc attggaggat agattgagtg
      901 atactaagtc tatcctcttg tttttctaaa gaactaagct agaatttttt cttttgtacg
      961 ttattatatg ttatttgtca ttaccaaaaa gcaccttttt tcttctagta tctatgacat
     1021 aagaaatacc acccatttcc tttacttgaa caaatcctac tgattcataa aatttttttg
     1081 ttttctcagt atcatctgtc aataattcga tttggactgg tccataacta gtgatcttct
     1141 ccaaagcttc attcaaaagc actttgccta ttccttggcg ctgatacctc ggatgaatga
     1201 ggatatcttg aataaatgcg atcgtcgcaa aatcagtgat ccaacgaacg attccgataa
     1261 tcttcccttc cccattacgc tttatcagag attcagattg ttcaaatgct ctagctaacc
     1321 ttgcagtgtc ttttgtgtaa ttcgtccaac caacgctctt atataattca gaaatctcat
     1381 cgatcataag ggaatcaata ttcatttttt tcttcctttc ttatacaatt ctccctctaa
     1441 taatacagtt ctttgactat ttaatctatc acatataact ctcctgtaaa gattctctcg
     1501 attccttaaa attcctcttt ccttttagaa tgcatacttt ttgataaata aaaaggttgt
     1561 gataaatttt cttcacaacc tctgtttctc tctatcaagt gttatctttt aattttctac
     1621 ccttacccta gcatctctat tgcccgtagt atgcatactt tccatgtttg cgaaaataat
     1681 gtttatctag taaatattgc gggatttcac atatattggg gttgatcagc tcgttttctt
     1741 tggccatcag acaaatttca tctaagatca aactgttttc tactgctttc ataggtgaat
     1801 ccccccatgt gaacggtcca tgtccataga caagtactcc agggacttcg tttggatcta
     1861 attttctttc cttaaacgtc tcgacaatca cattccctgt atgaacttcg taagcttctc
     1921 ttacttcttc tttcgttaat tggcgtgtac aaggaacctt accataaaaa gcatcagcat
     1981 gagtcgtgcc ataagctggc aaatcgcgtc ctgcttgcgc ccacatgacg gagtgcgtgg
     2041 aatgagtatg agtaatagca gttatatctt caaaagtttg atacaaaaca acatgtgtgg
     2101 ggagatctga agatggtttt aagctatctt cttctattat atttcccgac aaatctgtta
     2161 ccaccatttg atctgcttgc atgcattcat atctgacacc gcttggctta atgacgatga
     2221 ctcctagctc acggtccact tcactcacat tgccccaagt caatttgact aatccgtatc
     2281 gcggcaatgc cagatttgct tcaaggacac gttgcttcat tgctgcaatt ttttcttcac
     2341 aagacatcat agccagcctc cttcaattta gaacttaagt agtcttttgc ctgctggatt
     2401 tctcttcgaa agtcttggct tttttcactc cacatttcaa tcagaaatgt tccatcataa
     2461 tctagacgtt tcaaatgtct taataatcca agaaaatcaa cacaaccgct accaaaagga
     2521 acatcacgaa actggcctga atattctttt gttacagggt aagtatcttt taagtggata
     2581 gcagtgatat aatcgatccc tttctcaagt tctcgagccg gattattttc cggccatgcg
     2641 gacaaattgc ctaggtctgg atatacttgt agaaaaggtg aatgaatctg ttctttgatt
     2701 tctaaaaatt ttgaaatgga gttcataaat ggatcatcca tgatttccac ggaaagaatg
     2761 atgccatatt tagaagcttc ctttacgctt tcttttattc cttcgataaa gtcttctctg
     2821 gaattcattg atttctcttc ataataaaca tcgtatccag ctatttggat tactttgacg
     2881 cttagattat gcgccaaatg gattgctttt ttcattagtt gtttcgctgc ttttttcttt
     2941 tctggatcag cagaaccaaa cggaaatcgc cgatgcgcac ttaaacaaat cgaatggata
     3001 cgtacaccgg agctgaacat ctcttctctc agctcagcta tcttttcttc agaccaatct
     3061 aatcgtgcta accgctcatc cgtctcatca atcgacatct cgataaaatc gaagtccatt
     3121 tcttttacaa gggaaaaacg ttctttccat gaaatatctt tgggtaacgc tttttcataa
     3181 atcccaattt gagccatttc cttaccccca gatacgaatg atctcatctt tgaagttttg
     3241 tgcggccttc atcggatcat ttgctgctgt aataccacga ccagtgataa aggtatacac
     3301 atcgatccct tcaaataagt gtaatgtgtg tggatttaat ccaccagtta cagaaacatt
     3361 aaagcctagt tcaatcagtt ttttgatctt cgataaatct ttttcacccc aagtttcacc
     3421 agataacagc gcatcacggc tttgatggta gattacctgc cggataccga tgttatgcca
     3481 atccatggct tgttcaaaag tccaattgcc gtagagttct acttgcaatt cacctatttc
     3541 tttttgtgct gcctccatag ttggaatcgt tgcacaacaa atgactgtca tccagtctgc
     3601 tcctgctttt gcaacattac tcgccactgt tcctccagcg tctgcacatt tcgtatcagc
     3661 gactagtttt ttatctggga acatactgcg aatacagcga atcgcttttt gtccttcctg
     3721 taagcaaaga attgtgccca cttcaataat atctactaca tcaccaactt tcataacatc
     3781 tcctaatgca tgttctaagt cattgtgatc taacgcaatt tgcaaattcg gcctgctcat
     3841 cttagttcct tcctttactt gtttttttgg taccactttg tttcagcaaa tttttcactg
     3901 atttctttga ctgacatcac atttttgata ccgataactg taactccttt tttctctgcc
     3961 tgagtaaaca tattcaaaaa attgactggc gtaaaaacta catcgtattg gccagctgaa
     4021 ctttttccct ctgaaatggc acaatgatgg attttggtaa ttggtacgtt tagttctttc
     4081 attgcttttt ccacacttct catcatcatc aagcttgttc ctgatccatt tgcacacgat
     4141 actaaaattc tcatcttaat ccctccatta tgagtgttgt ctaatcagat tttcttttat
     4201 actctctgct tttctgcata tgtgtcatag tcttctacaa tcaaaaaata accatcagga
     4261 tttttccgat attgtaactg cggaatagcc aataaaccaa tgacaactac ggcaattcca
     4321 gcataaccta ggactttcat gattactgta aacaatggcc aagctgttgc ccagtcgaac
     4381 atcccgatat aaccaccgta tgttgacatc ccaatccatg tagcgaataa tgctgaaccg
     4441 cctacttgta tgattcctga aagaaacggg aacaggcaag cggctttgaa tccacctcgg
     4501 ttattggcat aaactgctat aacggcatta tcaaagaaca acggaatgaa accggctatg
     4561 acgatcgttg gtgatttcaa taaaatcagt aaaccaatca tcaaaaactg tcccaaagca
     4621 ccaaacaaga acccaatcgt taccgcattt ggcgaaccaa agccaaaagt agcagctacg
     4681 tcaattcctg gaacagctcc tggtaaaatc gtgtttgaga ttccttggaa agattgagtt
     4741 agttcatcga cgaatgtccg aacacctaat tgcaagatcg ccagatatac cgcaaaattt
     4801 aaagaagtcg tcataatgta gaataagaaa ctctgccctt cttgcatgaa ttgcgcttga
     4861 atcaaataat ctttgcctag tacaatcaga atgatcccaa agaaaaatag catgagtaac
     4921 gaagtagcaa ccatattctc attgaaaatc gacaagaatc ctggtaattt gatatcttca
     4981 atttttttgt cttgcttgat tgatctattt ttcttttcat cccgcttttt catccactca
     5041 gctaattttg caaatataaa gattccgaac atttgctgat gtgccactgc aaatccggca
     5101 ccttctgtca attcctgcgt gattcctact gttaagttag aagctactgt ccaataacaa
     5161 cctaaaatca gtcccataaa aatcaatgct tgtatcctac ctagatcagg aaagcaaaac
     5221 agtaaaatcc aaaaagcggt agctgcttgt tgaacctgaa cgtttccggt agtgaaaacg
     5281 gaacgcagtt tcgtatattt ctgaaaacgg actaataaga tatttaaaac aaatgcaatc
     5341 agtaataaaa tcatcacatc tccaaaggta cggccaaatg tctccattaa tccagcatcc
     5401 acagcatttt gtccaaaata aggatctgta accatggcat ccaaattgaa ccgttccttt
     5461 agtccaacca agattggccg aaaattattg accaaaccac cagagccaac agtcaaaata
     5521 aagtaaccga ccgttgcctt taagaatcca gcgatgcatt catgaagcgg gcgtttcagc
     5581 aaaatatagc ctaataacac gataaaacca atcaggtatg ctggctgcgt caagatattt
     5641 gttgcaaaat acgtccaaat gcttaacaaa aattccccca tcttttttct cctctatcaa
     5701 ttaattatat tctgccatca caacttggta atcatcgatg gagttcgtag agatgagacg
     5761 ctcaaccaat ccatctgtca ttaataattc ggataatttt tggatatttt ctagatgttc
     5821 ttctggatct tttgctgcga gtgtaaaaaa caaactagcc gttttctcct cattctcccc
     5881 ttcactttca aaacggattg gctgtttcaa cttggtaaat gaaatagctg ttccaaaaac
     5941 accatcactt ttttctgaag aatgcggcat tgctacttga ggtgcgatca caatataagg
     6001 accgtatttt tctacacaat ggatgatctc ctccacatac gtttcatcaa taatttcctt
     6061 atcgatcaat acaagacagc tttcggcgat agcttcacgc caatccgtga tttctttatc
     6121 tgggtaatga atcaattgat ggtcaaaaaa gtatttcagc aagaaactcc ccttctttct
     6181 tataaaaacg acggaaacgg tgtatcattt tcaatcgaga agacatcttc aaatcctcga
     6241 taaaaattaa actcaagatc atctttgttt gtcggataga tgaatttccc gcctacttgc
     6301 cagatataag gtttaaatcc atacttcagg cgatcctttt tgaatttcca aatttcagtg
     6361 atctcttttg gatcagccat aaaattagac caaatatcgt agtggacagg aatcactact
     6421 tttgcattca atgactccgc catgcgcagc atatcaacag aagtaacttt gtctgttatc
     6481 cctcgtgggt tttcaccata ggcccctaaa cagacatcga ttttgtgttc attaccatgt
     6541 ttggcaaata aattggagta atgtgaatct cctgcatgat aaagattccc tcctgatgtt
     6601 tcgaataaat agtttactgc aatttgatcc atctcctgag gcatttttcc ttttaatacc
     6661 tcttctggat cttcacaagt gaccaacgct gtccgatcaa acgcttctaa agctactaca
     6721 ttgatgtctt tgattttgac tgcatcacct ggctttactg taatcgtttt ttcttcagga
     6781 attccccatt tttgccacgt gcgaaccact tcttttggcc caatgaatgt tgcttcagga
     6841 caattttgat gaactgctgc ggctgtatgg atatctagat gatcggaatg gatatgtgta
     6901 acgattaaag cgtctacatt ttttatcgca aaaggatcga ttacgaaagg ctgagtacgt
     6961 aaattaggct gcatattttg aacgccactc atacgcatca tctgatggcc ttttttcatc
     7021 atgccattcc catgactacg ttttcccgtc ccacaccata gatcacataa aatattcgtt
     7081 ccttcatgac ttttcagcca aattcccgta cagcccagcc accacatagc aaaagttcca
     7141 ggatccacta cttctgtttc gatttcttca ttcaagtatg tgccccactc aggaaatgtt
     7201 tctactaacc acttttcttt tgttacttca ttgacagttt tactcatttg cttgctcccc
     7261 ccatatcgtt gttccaactt acaagtaaat attaatgtgt atcagcatcc atgaaaaccc
     7321 ttttatatga ccgtttgttt tttatatgat tttctttcag taatcaatga ttgtttcagt
     7381 ataataaaga cagatatgaa tgtttaaatg aacaactagt caaataaatc catggatcaa
     7441 gatgtccctc aggaggcaaa agtcatgaaa aactcacttg tcaatattga aaaacgtcaa
     7501 aaagaaattt tggaactgct tcagcagact gaacaactat caactttcga attagctgaa
     7561 tcccttgatg tatctattag tacgatacga agagatttaa atttattaga agaaaaaaac
     7621 gagatcatac gcaattacgg ttattgttct tataattaca aaaaccagac tgattttgat
     7681 caatctggtc ctgaaaggat taaacaagcg attgccagag aagctagtaa atacattaac
     7741 gattatgata cgctgtttat caattctagc tcgactgcgt tgaaaacact ggattttctt
     7801 caatctaacc atttgacagt cattacaaac aacgtgaaaa tcaattactc tccgcacaaa
     7861 gataattgta gttatatttt aactggtgga gagatgcgct ttccaaaaga agcactagtg
     7921 ggcgacatcg cattaaatac gatttcttca gtcaatgcag acatttgtat cattggctgt
     7981 agcggagtcg atgtagtaca tggggtcaca acaaagatat taaatgaatc aacgatcaac
     8041 gaaatgatgg tcaacaagac aatcaaatgt aagattttag tcgctgatca tcgaaaaatc
     8101 ggactgacat caaagttcaa gattgctgat atttcagtct ttgattattt gatcactgat
     8161 aaattttgtt ctgaaaaagt attagaggag atcagaaata cggggataaa aaccattcaa
     8221 gtagattcat tttaagaacc aggacgtaaa tatgtaaata ggattatcaa aaaaatgaat
     8281 aacaaattta tcgataaatg aaaaacacgc tacgctcaaa ttgataaagg aatcccaaga
     8341 tgtatccatc caatcgatac catcataatc tattgcttct tttataaccg ttatatgttg
     8401 cctaaatagg aatcaaacaa tatcgaaaaa aggaggtatg acaaaagtca cacctccttt
     8461 tttcgaataa acggtattca aatcagaaca ctgatttcac aaccacttta tttcaggtcg
     8521 ttttcaatca cctttaccgc gtaatcattt ccgttgaaac gcgctatttt ttttgcgtcc
     8581 atatatcttt ctaaataatc atcttctcct aattgcttat ggcaagaagc aatttcataa
     8641 agcaagtatt ccaatgcata agtcgattta tgtttcttat tatactcaat acccttctca
     8701 cataattgga ttgctttatc ataatcctcg attttacggt aataggtggc gatatcataa
     8761 tatacaatgc agaccatcag attatcaaaa tcagtctcac tcaatatttt aagtgtacgc
     8821 tccacataaa ctttcgcaaa atctaattct ccttttgaca agtagatcat tgccacgttt
     8881 gcagctgctt gtaagtgatg gatatctgtt tcggtcgttt gttccaacac ttgattaaaa
     8941 taaaataatg ctgcatctgg ttttttcgca taaagatgat caagcagtcc ttgataaaat
     9001 aaaatttgat ttaaaagatc agaattactt actttttcct gatcgatcgt ttgtaaaatt
     9061 ttataagatt cttggtattt tgatacagaa ttcaatgatt gaatctcatt tatttttttc
     9121 ctgattttgt cttcttctgt ttctactaat atatcggaga tctcgacatt cagctttttg
     9181 caaagcgcac ttaagatatt gatgcctggc gacatattct tgttttcgat attgctgaca
     9241 gttgcttgtt cacaaatgcc ttctgctaat tgtacttgtg ttaacccctt tttctttcgg
     9301 tattctttta gtaatgctcc atctacttta atcaaaacaa tttccttccc tttaaaaaat
     9361 tatttctcct ttatatcata cacaaaaaaa agttctaaac aaccaaaaat gtttagaaca
     9421 gaataaaaat tttaatttta aaataatatt caaattaaac aactggcgta tctgctcctt
     9481 gatttctttt tgtgttatct gaataattat cgtttacagt tataacacat agtgaaaatt
     9541 gtcatggcga gaaagtctaa gaatattttt aaacataact atttctttct tacgtgtgta
     9601 taatgacgac agcacaccta tcaattaata taattatttt atttttttat gttctcatgt
     9661 ttatttttaa tgacacaact tctcgtattt atctggcaca acatataaat cgatcaaaaa
     9721 attgttgcgt gtttttttga aaattggagt ttcaacttga ttacaaaatt taaatttaga
     9781 agttgtgaaa acagcgagag acagtttaat attcaaaata tacataggct actcgaacgc
     9841 tgtgtttttt agtatactag taagaaacga agggatagac tcattccaat aaggaggatt
     9901 tcatgaagac aattcttttt gctcctgcag tattcaattt agctgagaca acacgaatga
     9961 ttgaggttgc caaagctatg aaagaccgtt attactgtgt attctttggc ttttctaaaa
    10021 cttttgctcc tttgatcaca gaaagtggct ttgagtatca tttactagcg ccgatcctta
    10081 cgaaaaaaca agaagaacaa atcataaaat ttgaccagtt gcgtacactt aaaaaccctt
    10141 ttaccaaaga aatggttgcc tctcgtatca ctagtgaaca gagtctgatt gctaagtttg
    10201 agcctcgact gattgtgaca ggttcgaatg tgacaatttt tttatcggcc cgcaataaaa
    10261 agattccttt agtatatgtt aaaccctatg ctttgagtga accttttttt caatcagagc
    10321 atgcgctgat gccccacgag ttacgtttct tcggcccttt aagcaatccc ctttggcact
    10381 ggacaaaaaa gcgtatagta aatacccgat ggatccccaa tgccttcaaa cacgctgcac
    10441 aaaaagaaat gcttccttta ccaaaaacaa gtttacaaat gatggatgct gatctaaatc
    10501 tcatcacaac gcctaaacta tttttggaag aagaacagct gccggaaaat tatcgaatcg
    10561 ttggtccaat ttttgctaag ctcagtactt ccttgcctga agaagtgcta acttttatac
    10621 agcgaaagca acaagaaaga aaacgtatta tctatttcgc aatgggtagt tcaggcaatc
    10681 cgcgtatgtt acgcaaaatt ttgttcttct tacaaaaaca accggatcta gcggttattg
    10741 cacctattga ctatctgctt gatgacattc aatctgactc agaagatctt ttaataacag
    10801 aatatctgtc tagtcatctt ttgcatgaat tcattgattt ttcttttatc cacggcgggg
    10861 aagggaccgt ccaaactgcc tgtgaatccg gcaaaccgtt tatcggtgtg gggatgcaat
    10921 ttgagcaaag ctgtaatatt gactattgtg taaaatacgg aaacgcaatc gccctcacaa
    10981 aaccagtgac tgaaagaaaa ctgcagattg ctctgcgcga agtttcttca cccaagattc
    11041 gtcagcaggc acgcacgctg caagccgttt ttccaataaa tggtccacaa caagcaattc
    11101 aagaaatcga aaccttcctg agcaaccacc caatatagtt tcaagtagaa aaagcttttt
    11161 taatagagac tcatcagtaa tttcgctatt cgagacccag acagtgaaaa tacaaaaaaa
    11221 gtaaatagtg gattgaaaag ttagagttac ttaaattacg gtgtctaaaa aacacaaaat
    11281 catccttaaa ataaaagatc tgacgctatc caaatgagca taggtagcgt ctgccattta
    11341 ttcttagtca aattctttga cacctttctc tggttggatc atctcaacgt ttcttcaaaa
    11401 gaaagaccat aataattagg caaatacatt ttcttaaaat gtgtcatata gatctagaag
    11461 catcgctttg tagagatttg tgccgctagt cccctcaaca attactaaat caaatgtagg
    11521 atttaccact ttatctttga taatcaacct ccctcttctg ttgagacaat gatctcgcaa
    11581 tccgatgcat actcctatat aaactgccag caatccccac atattgagta gatcatgtca
    11641 gaatgttcta tgtcgtcagc aacgatacac taaaagtcac gttcaccatg actgattgct
    11701 attcccagca caattatttc tatacacgtt tcatgatttg aataaacact cacatcatac
    11761 atattaccat tcatacacca tactgcagcc cctactatat ggttgtaagc tcccaaatct
    11821 atatttgact tgatcacttt ggtagtagat ctactaattc taaatccatt gctgataaaa
    11881 tttccatttt ttcctccttc tttctgccaa aacagttaaa acaataataa tctttatgta
    11941 aaaaagggct gtgacaaaag ccttgtcaca gtcccatatt ccgaataaac ggtggtcaaa
    12001 agcttgcatc tgcggtaata agttcaacca aacgaaaaat aagccaacat ttcacaaaaa
    12061 tttaagaagc aattttcgta aatttcttct tatttcttga agctaaccac ttctgttaca
    12121 accactttta gaacatttaa agcttcgatg tgacaaacca tctatgctgc tcgatcataa
    12181 aattgatagc aaaaattcca caaagtacat atgtccccca tgaaaacaaa acattcatat
    12241 gcggtacaat gatctttgga agaatcacga tcaaaaatga tgccagtgcc caaatccatc
    12301 gattgatttg aatatgatat gtagctagca tattcaatat aaggtgacta gccgttaata
    12361 aaaagataaa aacaaaaaat aaaatcagcc aatacattgt ttcccacctt ctaaaaacca
    12421 aacttagaca gtctggactt cgttttctcc acgactttgt tcatctgaca gcatcttttt
    12481 atcataagct tttacaaatg gataatagat aataaatgct atcaatgtgt tgatcatgat
    12541 caagataaca acacgccagt catttcctgc tgaaagataa ccgccgattg gagctggtaa
    12601 tgtccatgtt ggcaaaacag taaatctatt gaccatttct aatttgactg caaaataact
    12661 gataatagtc aaaactaaag gaactaagtt gaacgggatg aacatgtaag gattcaacat
    12721 cataggagct ccaaaaatta tgggctcatt gatattgaag ataccaggaa taatagaaaa
    12781 acgaccaacc tctttcaaga attttgattt acagaagaat ataaacaaaa cagataccac
    12841 gatcgttgct cctgcaccac caattgttac cgtccattga taaaactgtt caggagcgat
    12901 atagggtaat tgggtggcag ctgtaccatc tgccaatgcc tttgcattct catccaacat
    12961 gatcagccac attggacgaa caacagcccc tacaatactc atgccatgga taccaaatga
    13021 ccacaacaaa tggatcaaaa acattggtag taaaacacca agcaaattat tccctaaaat
    13081 attggttaaa ggctcgaata acgataataa ggcagcgttt acatcaaagc ccgcgacgct
    13141 tcgaatcagc caagtaattg ttaaaatgac tgcacctgga atcaatgcct caaaactacg
    13201 ggcaacagca ggtggcactt gttctggcat tttgatagta atatttcgat ttttaaagaa
    13261 acgatatact tccactgcaa aaatcataga taagatcccc gcaaacatcc cagatgctcc
    13321 caaagaactc ataggtaaga cccagccaag aggtgcctct tcaggagtta aaacgtttac
    13381 aggaacttgt aacataaaga acgttcctaa agataatata ccacctgtca cactatctaa
    13441 tccatatgat ttagctagat ccgaacccat aacaaaagtt gcataaatag ccatcaatcc
    13501 catcgtcatc ctaaagggta aaacaatcgt tgccgaataa ggggcaataa attcattcca
    13561 tccaggaaac ggtaaattga taaagaccat aaaaaatgtc ccaatcaaaa tcaatgacaa
    13621 tgttgaaaca accccattac gaattgctaa taaatgacgc tgtgtaccaa tttttgccat
    13681 tggtgggaca agtttctctt cgacccattt catcagcttt tccactaaaa ccactccttt
    13741 tcaataaaat atgaaccatt cattgcatga caacgcaaag aatgttcata actaattata
    13801 taattaagaa attttatttc aatatattct cttaaataat caaatttatt tttaagaatc
    13861 ctgaaaataa gttttctaaa tcataggagc aacaaaaaaa ttcgataatt aacaaaaatc
    13921 aaaatgatta aatctagtga ttgaaacata tcatttcaaa aaaattttgt aaattcaccc
    13981 ataaatatca ccctatttaa cttttttcat cgtacactaa aattcaaaac aactatcttt
    14041 aatctttact tcttggtttt gttttaataa atttccttca aaaatgcctg gagaaactac
    14101 aatgatcacc gtatcttttt gtgcttgctc caacttcttc aaatctataa tagctaacag
    14161 tgtcccttct tttacctcct ggttactttc aacccgtatc tgaaacggac ttccttcgag
    14221 ttcaactgta tctaaaccca tatggatcag tatttttctg ccagattcac tttcgatcgt
    14281 tatggcatgt cgggtaggaa atatattatc gattattcct ttaactggcg catggatata
    14341 tccatcatga ttcgttatag cgtatccaac tcctatcatt tttgaagaaa agacctcgtc
    14401 ttttactgct gttaatggaa taatttgacc actagctaca gcttttagaa tgtttcttgt
    14461 tttaaagaaa tgcacttttt atcacctcta ctttaatgct ggccaatatt ttttgtttac
    14521 tttgatcatt tcatctagta ttttttttgc gactctggca tttggtacgg tttgattcaa
    14581 tgtaaatgct tgtaaagctt tttgataaga accttcaaag taagcatcta ctagtaactt
    14641 ctctactgca acttgtgcct ccatcaatcc tttatgaaaa tcactgattg gttttcttag
    14701 tgtaattggc tccacaccag ttgcaccaac atatgccggt atttcaacaa ctgcatctga
    14761 ccgtagattc ggaatcgccc cttgattagg aacgattagc ataaagcgac gacgatcatc
    14821 attcaacaag gaaatagcta tatcgacgat atattgtcca tgctccccaa aattaaagtt
    14881 caatacttct tccacaatac cgcggcgtat tttatcagcc atttctttgg tatttttctc
    14941 tcgtccatcc atgaccatat tagcacgtgt atactctttg tcagtatgct caacgaccat
    15001 atcaggatat aagtaatact ctaagtaatt attcgggata ttacttggaa aatttttcgt
    15061 gatgactgac atcatttgaa aggttttttg ccaagtttta tctcctatat taaaatcggc
    15121 gacttgcatt tcttttgtta ttagtttttc aataatctct ggcataattt ctcgttgcaa
    15181 ttctttatca taaatcgatg tataccagcc aaagtggttt aaaccataat acgtaacgat
    15241 ccaattctta cgatcataac cgtaattcac tgcaatcgtt tcttcaattg aaatagtcat
    15301 atcacaggca ttaatcattt ttacattcgg atatttacga cgaacagctt cagaaacgat
    15361 cgactctgga tttgtataat tcaaaatcca tgctttgggg gcatagtctt gtatatgatc
    15421 gacaatttcc aataaacctt tgattgagcg catcccataa gcaaatcctc cgagtccaca
    15481 cgtttcttgt cctactaatc catgtttaag tggaatcttt tcgtcctttt ctcgcatctc
    15541 caatcctcca acacgaattt gtgagaaaac aaaatcgcat cctgtaaaag caagctttgg
    15601 atcatccgtt gcacgaatgc gaatatttga aaaacctttt cttttcagca taaatttaac
    15661 aatcaagtac atatccatat ttctttcttc atcaatatca tataaacgta tttcagataa
    15721 tggcaaccgt ttttcattgt tcaaaatggc ttgaacgatt cctggtgtat acgtactccc
    15781 gcctccagct atagtgataa tctgtttttt catcatcatc ttttcctttc tattcttcta
    15841 ataatttatt gaattctgcc ataacataag tcacttctaa gccgatgata atttgataat
    15901 ttttttcagt tggtttaatg atcccgctta tccctaattg cttgattcgc tgttcctcga
    15961 ccatggtggg atccactacc tctacccgta ggcgtgtatt acaactatag acatccagga
    16021 tattggcttt tcctccaaac gcttgtagca tttttgttgc catatattca taatttttac
    16081 ttgctaaccc taactctgtt tcttctaagg ttacttcatt gccaaactct gccttagctt
    16141 cacgtcctaa tgtctgaatg tttctcttat tgatcaaata ataaaaagta acgtaataca
    16201 aggcaaaaaa gaaaattccg attggaagaa tcaaaatagc attggtagcg attcgaaaat
    16261 tgatgagata atcaacaata catgctccga atgtaaaacc aattcgtata ttgaataagt
    16321 aacagacaat ccctgctaaa ccggcaaaaa gtgcatggat cacgtacaac ataggagaaa
    16381 gaaacatgaa actaaattca acaggctcag tgatatttgc aataaatgaa gttcctgcac
    16441 cgcttcccat gattcctttg accatctctt tattttcttt ataagctgct ttatagatag
    16501 ctagacatat agctggtata ccaaacatca ttactacaaa aaaaactgat aaaaacagtc
    16561 cagcctgagg atctccgttg ataaagcgtg tcatctctcc tctgaaaact tccttgctag
    16621 gagatgtata gcttcctaaa tcgtaataaa tatacgtatt caacacatgg tgcagtccaa
    16681 aggggatcag caaacgattc aaaaacataa atatccccac acctaatgct cccatatcaa
    16741 cgagcagttt tgcaaaatta tcaatcccaa tttggatgag cggccagata aagcccaaaa
    16801 aaacagctgc gattgtttgt agaatcatca ccatagtcaa tgggaatttt tcgcccgcaa
    16861 aataagaaaa aactactggt aatttttgtt ctttaaagcg attatacgtc catgccgcta
    16921 ctaaaccgga aataattcca ccaaaaatcc ccatattcac ttctgggtcc ataatttcta
    16981 agcctttttt caaggtagca atcgctaaaa aaccagtaag tgcaggtatt cctttgtcct
    17041 tatttttgac aaaaccgatt gcaactccta tagcaaataa gatatccaag tttccaaaaa
    17101 cggcatttcc agctgcacca attactggga tgttcagcat atcgtcagct gataaacgca
    17161 tgatcaatcc cgctaatggc atcgctgcaa ctggaagtag catcgctctt ccaagcttct
    17221 gcacatttga tttaacattc atttttattc ctcctctatt aaatatcctc atatgttact
    17281 aactcaatca aaggatcatt tttcactttt tgagcaaatg ctgaatgaat taaaaattcg
    17341 acttggtggg tacgaggata cacaaaactt gaaccattta acaattcctg atccaaatac
    17401 gctgcgtgac acatgacttc gatcgtttta tcttctctca atatcatgag taaacttgcc
    17461 aaatattctt ccacactcgt attgatttgt cgtttttttt catcagtttc tcctacgaca
    17521 tcgaaacaag gctcaaaata atcgacatga cgaacttcat cttttcgttc aaagttgctc
    17581 cgaaccggca aatcatattt ttttgctaat gtaacaacta cctcctgatt ttcatccaaa
    17641 gtatgagtat gatgatgact gtctaaatga gttggtatga tccccgcatg ataaattttt
    17701 tgaatctgag cattccattc ctgatacagt tgatctttgt caatgttaaa tggatgctga
    17761 taataagata aggatctgaa ctctccgctt tcgataagag tatcgacagt tttgaggagt
    17821 ggtttgccac acgtcaatgt taaatggact cctacaccta gcctaggcat ttcctttctt
    17881 agtttcacag catgctcgaa acccggcata tttgccatca atgtagttga tgtcaaaatt
    17941 cctcgctgat aagcatccat aatcccataa ttcacaccat ggctatagcc aaaatcatcc
    18001 gaattaaaaa tcacttttcc catttcattc tccttctttt ttctactaaa ataggcgcaa
    18061 ccaaataatc atagtccatt tactatgtgt catttggttg cgcctataga tagttacgcc
    18121 cttattttaa tagattcttg ctagatgaat tgccaaatag atgatttcat tttcttgaat
    18181 ggcaagttga aattgctgtt cgatgatatc tttaatcttt agtgctgtac aatacgcttt
    18241 gctatgttta aatgtttcag taaaaaaacc aatattttct actggcgttt cttcctgata
    18301 aatcaagcgt ttaaccagga atttgatatg aaccattaag cgatgataag tcagtgattc
    18361 tttatcataa acgtttgaat aggatttttc tagatgggac aaaatcgtgg tcgtcatttc
    18421 tactattttt aagctcttta aactattagg ctctcctagc tcagcattaa tgatatgcat
    18481 agtgatgaat cctacttcat ttgaccctaa ctcggtttga tatcgatgat tgattcgctc
    18541 gaccacttct actgctatat catattcatt tggataaagg aatctcattt ctggcaacat
    18601 aattgctgtg acatctctat cttctctttt tcgttgaata gcaaaataaa tatgatctgt
    18661 caatgtaata tagatatttg aatctaatgg agaggagatc ctagctgtta tcagttcaat
    18721 cacttcttcc gcaaaatcca taaattcgat tggaatctgc gagactatct cactgaatcg
    18781 tttgatcttt tctttagaat ctaatacaaa taatttgtca gcatcctcaa catcaaatgg
    18841 cttactcact ttagcagaaa agccaatccc tttccccatc gcaatttttt ctattccatc
    18901 gtcatcgatc aatacagcat tatgattcag ctttttcatc acatacaccg ttaattcacc
    18961 tcctctatat gataaaacaa aacaacttgc agactccttc atacatattt ttgtctccaa
    19021 acaattttta aagacaaaaa acgacctaag aaagaaccct ttcttaggtc gtgcctaatt
    19081 gaatagtagc accctacata atttacaaaa atagtttaac acataataaa agcgttatca
    19141 atatcttttt tactcgtttt atgataatac ttgtatcgaa ttgatttgga ggtaattaca
    19201 taaaaacaaa aaaaatatag caactctcta taagaaagtt gctatattga taattatacc
    19261 ggcggccggg gtcgaaccgg cacgtcctca acggacactg gattttgagt ccagcgcgtc
    19321 tgccaattcc gccacgccgg caaatttaaa aataataact ggggtagctg gattcgaacc
    19381 aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca agaataaagg
    19441 gcgaatgatg ggaatcgaac ccacgaatgc cggagccaca atccggtgcg ttaaccactt
    19501 cgccacattc gccatcataa aagatgttat ttaatttctc aataaaaaac taagatgaag
    19561 acatcttagt caataccggc ggccggggtc gaaccggcac gccctcaacg ggcactggat
    19621 tttgagtcca gcgcgtctgc caattccgcc acgccggcaa gttgatttat tagtactaag
    19681 gcggtaaccg gatttgaacc ggtgatgaag gttttgcaga cctctgcctt accacttggc
    19741 tataccgcca ttatactatt atcaatctat aaaataaaga ataaattata gaaactgggg
    19801 tagctggatt cgaaccaacg catgagggag tcaaagtccc ttgccttacc gcttggctat
    19861 accccaagaa taaaaagggc gaatgatggg aatcgaaccc acgaatgccg gagccacaat
    19921 ccggtgcgtt aaccacttcg ccacattcgc catggcaggg gcagcaggaa ttgaacccac
    19981 actaacggtt ttggagaccg ctgttctacc tttaaactat gcccctataa aatggaggag
    20041 agtggattcg aaccactgaa ccctaaggaa cggatttaca gtccgtcgcg tttagccact
    20101 tcgctactcc tccatggtgg cgcgggacag aatcgaactg ccgacacacg gagcttcaat
    20161 ccgttgctct accaactgag ctaccgcgcc atattttaaa attattaatt gaataacaag
    20221 aacgacggtt ccgacgggaa tcgaacccgc gatctcctgc gtgacaggca ggcatgttaa
    20281 cccctacacc acggaaccag ttcattatgg aggttaacgg gatcgaaccg ctgaccctct
    20341 gcttgtaagg cagatgctct cccagctgag ctaaacctcc aacattcaat taaaatgacc
    20401 cgtacgggat tcgaacccgt gttaccgccg tgaaagggcg gtgtcttaac cgcttgacca
    20461 acgggccagg taaatttgct acggagagta agggattcga acccttgaga cagtttggca
    20521 ccatctacat gatttccaat catgctcctt cggcctctcg gacaactctc cagagtgaaa
    20581 gaagctcaat actctttctc aaaatgagaa ctccggcagt aggactcgaa cctacgacat
    20641 catgattaac agtcatgcgc tactaccaac tgagctatgc cggaataaca tcagcgtggc
    20701 gacgtcctac tctcacaagg ggcaacccct cactacaatc ggcgctaaga agcttaactt
    20761 ctgtgttcgg catggttaca ggtgtatcct tctcgctatc gccaccacac tgtggtgtta
    20821 tcttttattg agtaaatttt gttcactcaa aactggattt gaagtcacat aagttttttt
    20881 ccgagt
//
LOCUS       DADVXE010000048        19751 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.049, whole genome shotgun sequence.
ACCESSION   DADVXE010000048 DADVXE010000000
VERSION     DADVXE010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19751
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.049"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            6..305
                     /locus_tag="KB913_001922"
     CDS             6..305
                     /locus_tag="KB913_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6820264.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="KB913_001923"
     CDS             378..1739
                     /locus_tag="KB913_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBB6820265.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="KB913_001924"
     CDS             1761..2021
                     /locus_tag="KB913_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820266.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="KB913_001925"
     CDS             2035..2787
                     /locus_tag="KB913_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBB6820267.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="KB913_001926"
     CDS             complement(2881..3486)
                     /locus_tag="KB913_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6820268.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="KB913_001927"
     CDS             complement(3539..4513)
                     /locus_tag="KB913_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBB6820269.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="KB913_001928"
     CDS             complement(4891..5610)
                     /locus_tag="KB913_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6820270.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="KB913_001929"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="KB913_001929"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBB6820271.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="KB913_001930"
     CDS             7161..8558
                     /locus_tag="KB913_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6820272.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="KB913_001931"
     CDS             8639..9079
                     /locus_tag="KB913_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6820273.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="KB913_001932"
     CDS             9227..9553
                     /locus_tag="KB913_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6820274.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="KB913_001933"
     CDS             9554..10303
                     /locus_tag="KB913_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820275.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="KB913_001934"
     CDS             complement(10383..10838)
                     /locus_tag="KB913_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBB6820276.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="KB913_001935"
     CDS             complement(11265..11540)
                     /locus_tag="KB913_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820277.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="KB913_001936"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="KB913_001936"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBB6820278.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="KB913_001937"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="KB913_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBB6820279.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="KB913_001938"
     CDS             14770..17436
                     /locus_tag="KB913_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6820280.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="KB913_001939"
     CDS             17800..18552
                     /locus_tag="KB913_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6820281.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="KB913_001940"
     CDS             complement(18574..19728)
                     /locus_tag="KB913_001940"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBB6820282.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
BASE COUNT         6290 a         3468 c         4053 g         5940 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagctg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga t
//
LOCUS       DADVXE010000049        19634 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.050, whole genome shotgun sequence.
ACCESSION   DADVXE010000049 DADVXE010000000
VERSION     DADVXE010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.050"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="KB913_001941"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="KB913_001941"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBB6820283.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="KB913_001942"
     CDS             complement(1172..1867)
                     /locus_tag="KB913_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBB6820284.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="KB913_001943"
     CDS             complement(1880..2596)
                     /locus_tag="KB913_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBB6820285.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3534
                     /locus_tag="KB913_001944"
     CDS             2926..3534
                     /locus_tag="KB913_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBB6820286.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3859..4182
                     /locus_tag="KB913_001945"
     CDS             3859..4182
                     /locus_tag="KB913_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBB6820287.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4364..5734
                     /locus_tag="KB913_001946"
     CDS             4364..5734
                     /locus_tag="KB913_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBB6820288.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5864..7165)
                     /locus_tag="KB913_001947"
     CDS             complement(5864..7165)
                     /locus_tag="KB913_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBB6820289.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7519..9477)
                     /locus_tag="KB913_001948"
     CDS             complement(7519..9477)
                     /locus_tag="KB913_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBB6820290.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9654..9920)
                     /locus_tag="KB913_001949"
     CDS             complement(9654..9920)
                     /locus_tag="KB913_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6820291.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="KB913_001950"
     CDS             complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="KB913_001950"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBB6820292.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="KB913_001951"
     CDS             complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="KB913_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBB6820293.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13264..13827
                     /locus_tag="KB913_001952"
     CDS             13264..13827
                     /locus_tag="KB913_001952"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBB6820294.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14080..14601)
                     /locus_tag="KB913_001953"
     CDS             complement(14080..14601)
                     /locus_tag="KB913_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBB6820295.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14604..15446)
                     /locus_tag="KB913_001954"
     CDS             complement(14604..15446)
                     /locus_tag="KB913_001954"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBB6820296.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15439..16164)
                     /locus_tag="KB913_001955"
     CDS             complement(15439..16164)
                     /locus_tag="KB913_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBB6820297.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16340..16636
                     /locus_tag="KB913_001956"
     CDS             16340..16636
                     /locus_tag="KB913_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820298.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17204..18796
                     /locus_tag="KB913_001957"
     CDS             17204..18796
                     /locus_tag="KB913_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBB6820299.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18809..19549
                     /locus_tag="KB913_001958"
     CDS             18809..19549
                     /locus_tag="KB913_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6820300.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5620 a         4028 c         3725 g         6261 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcaaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 gaaagcacag gtgaaggtgg cgaaccagaa gtgatcggtt caacagaaga ataatactga
     3541 aacaatcagg tggtgttaga agcggcgggt cagcagcttt taacacgcct tttttatttc
     3601 taatcgttta ttttcatatg gggcttccac ttttgtaaat ggctttacaa acgaaaaatc
     3661 ctaatttacc aagcttttcc tcgcatactt ttatcgtacc tttataaaaa tttatacttt
     3721 gaaaaaaagt attcaattat tgttgcattt ttcctgattc tttattagaa tgaaccctcg
     3781 ttgaagtaag tatttctagt ttatcctagg attaattata aaaataaaac attcgttgat
     3841 tcgaaggagg ttaaacagat gtttgaaagt tttgatagca gccgcaaccg ttacgcttca
     3901 gttggtgtcg tatcaagttt gccagatgaa ttgattgaca gtatatggtt tattattgac
     3961 ctagatctta agggagtcat tccattagaa aatatattaa cctttgattt gatcgaaaat
     4021 cgtggaaaag tgacgatgca tttttctcaa gcaggaagca atgtggaaat ggatattgat
     4081 ttgccgtttg cctattcgaa ccaatttcct gctcaagtat acgcctatga tgacggtacg
     4141 agagaaacga tccttttacc aagtgagatt agacaatatt aaggtgatag ataaacgtgg
     4201 atgtccctta ttttacagac caggccaagt tgttgattct ttgactcaat tcttggcttc
     4261 tttttatgga gtttcataaa ttatcattga tttctaattg gtattctcag gataaacgct
     4321 atatactact aactaaattt taaagatata aggagtttaa aagatgcgcg atttaacaaa
     4381 aggaagcccc gctaaactga ttttgatgtt cactgttcct ttactgatcg gaaatgtttt
     4441 tcagcagttc tacaatatga tcgatatgat catcgtgggt cagacgctag gtaaaaatgc
     4501 gctggcagcg gttggtgcaa ctggaagcct gacatttttg atcattggct ttgcccaagg
     4561 tttaacagct ggtttagcca ttattaccgc acaacgttac ggtgcaaaag attatcgggg
     4621 tctgaagaaa agttttgctg ctagtgttgt cattagtctt gtcgtcactg tgattttaac
     4681 tgtcctaagt ctcctgttta ttcgtccgat gcttcaattg atgcaaactc ctcctgaaat
     4741 acttgatcaa gcacaaacat ttatttcaat tattttatta gggatctttg catcagtcag
     4801 tttcaatttg ctttctaatg tcattcgcgc acttggtgac agccgcacac cactattctt
     4861 tctgatcatt gcggtcatca tcaacgtcgt acttgatttg atctttatta tctattttgg
     4921 catgggtgtg gaaggtgcag ctattgctac agtaatcgca caagtttctt ccagcgtact
     4981 gtgtctagtg tatatcaaga aaaaaatgcc tttgttacag ttacgcaaaa aagatttcaa
     5041 atttgaaaaa gaagagtttg ctgtacacct aaatgctgct ttgccaatgg cgtttcaatc
     5101 ttcgatcatc gctgttggtg ctatcgtgtt acaagcagca ctaaatagtc tagggacaga
     5161 tgtcgtagct gctcaagccg ctgctggtcg tatcgaccaa tttgcaaatc agccgatgat
     5221 gtcatttggt attgcaatgg caactttcac tgcacaaaac tatggtgcga aagaatatgg
     5281 ccgaatcttg caaggggtac gtcaaacttt actgatgagt gtcggattta gtctcttagc
     5341 aggtgctatc gtcattttct tcggtcattt ctttgttcaa ttgtttgtta gcccatcaga
     5401 aacacgtgta tttgaattag cacaaaccta cttcaatatc aatgggtctc tttactggat
     5461 cttagcagtc ctgttcattt tacgctacac acttcaaggg cttggacaaa gcaagatccc
     5521 tacgatcgcc ggtatgatgg aattgcttat gcgttctttt gcagctatcg ttcttacagg
     5581 aatgtgggga tacccaggag cagcagcagc ttctccttta gcttggatcg gttctgttgc
     5641 cgtgttgctt tactcttata tgcgttcgat gaaacaattg aaacacatgg gtgaagagga
     5701 acatttcaca ttagaacatg cagaagcaag atagccttga ttaaaagaaa tcgttgcggc
     5761 taaaaatgaa aacttttatt gaaaatatct tcttcgttta ccgaaaacag gttttttaga
     5821 taacaaaaag gctgtgacaa aaaatgtcac agcctttttt cttttattct gtttttcttt
     5881 ccgtggactc tactttgaaa taatcgatat gtgcatgctg gtattctaat accgtgaaac
     5941 ggaatgatgc aatctcaatg attgttcctg cttttatttc tttatatcgg ctagaagcaa
     6001 agcccgcaag tgtagtaaaa ttcgtttctt caaactctgg aatctctaca tgaaaataac
     6061 gctggaaatc atctaatgtt agtttgccgg agatgatata agagccatct gactgttccg
     6121 ctatcaatgc ttcgtccaaa tctgtctcat ctcggatttc cccgacgatt tcttctaaaa
     6181 tatcttcaat cgtcactaag ccgcttgtcc ctccgtattc atcttttaag atagcaatat
     6241 gcttaccctt ttttcgcatg atcgtcaata atttttttat agggatcgtt tcagttgtta
     6301 cgatcggctc ttcaatcaac tgttctactg tcagctggtc atctttataa gattgcttga
     6361 tcaaatctgg caaggtgaca taacctaaaa cattgtcttt tgattctaag ataaccggat
     6421 agcgagtatg tccttgttca atcgaagctt ttatcgcttc tttgacggtt tctgaagctt
     6481 cgaatacttg catggacgta cggtctactt gtatatcttt tgccaaggta tcatcaaatt
     6541 caaacacgtt ttccaaataa taatattctt ctttggtcaa ctctcctttt tcataagaat
     6601 tcaatgcgac taatgtcagc tcttcttgag acaatgtctc ttctccttca gatacgagac
     6661 gcacacctaa tagcttccct agccctgcag ctgaatgatt caatacccaa ataaaaggaa
     6721 acattacttt ataaaaataa tgaagtggtt taactacgaa caagacgacc ttctccgtat
     6781 tgacgatact atagctctta ggaagcagtt cgccaataac cacatcgata tacgtaacta
     6841 aaataaatcc cagcgccaca gagattgtac tgctaatagc cgaactaaaa ggtagtttac
     6901 cgatcactgg ttctagtaaa gccgcgacag atccttcacc gacccacccg atgatcaaac
     6961 cggttagcgt aattcctaat tgactagctg ataaatagtt atctaaatgg tgtgtaacat
     7021 gaagagctag cttggcgttc tttacatttt ccttttctag ttgttccaat cttgatcgtc
     7081 tgattttcac taaagcaaat tcacttgcta caaaaaatga agtaattgca atcatcaaaa
     7141 ataaaataat gaaattgata accatattct cccgcctttc tctttttcta ttgtaccctt
     7201 tttctacaaa aagattgaaa ataatgcgta ttcatattta ggaataaaaa aggagatgcg
     7261 gcatttttca gccacatctc cttatcactt caaaatcatt gcgttacttg ttgctaaaca
     7321 gctttttcat gacctctgat aaaaacggta ttcaaaagct tgcatctacg gcattaagcc
     7381 caaacagatg aaaaacatga gaagctgttt ttatctgctc gttcttactg cttgttgcag
     7441 tacagctttt tcatgacctc tgataaacgg tgttcaagta gctgacattc gacattagtt
     7501 caggtcaaag cgctactttc acaaccgctc tttcaaccat gttttccgag tatttccaat
     7561 gataagcgga acagtttcat gttttacttc gctgtactct agcccaaacc atgtttctgg
     7621 cgaggtagcg atttttttga ttgccagttt tgcctgcatg atttgacgtt gccattttcc
     7681 tagagttgtc acattggaaa ctacttcatc aatcaggaca aattggaaat cgccaacttc
     7741 tcgccctggt gtcagagagt atctttgtgg ctgttttggc aaacggcctt gtttcatcaa
     7801 atcatggatg acttggcgaa catatacgtt gatttcctgt tggaccctga aacctaagaa
     7861 cagattcact tggacaataa aatcagtgtc catcatatct acttgatatt ctttcgtata
     7921 tggctcatcc gtcacttcca catgaacaaa ccaatagact cgtgctcttt taggccgttt
     7981 atctaaaatc gaatagatga actgtcggcc aactttatct tcagccatat caggaaccaa
     8041 gaagaccaca tttgtctgat agattggtaa agaagtatca tcacgtaatt ctctaagctg
     8101 cgggatataa tctctcaaag acacatcctc ggttgacgat tcgcgaataa tgttcccttg
     8161 ttcccaaata aacatcacga ctaagatgat caaaccaatc agaacggcta caaaaccgcc
     8221 tcggaagaat ttgacaacac ttgagataaa gaaaacgact tctatcgcac cgaagaaaaa
     8281 ggtaactaaa tatgcaagcc aacgagaatg cccattttgg ataagataaa agtaaagcag
     8341 tgctgttgtc atcaacatcg tcacagtgat cgatagaccg taagcagctt ccatatgatg
     8401 agacgttcgg aatgtgacaa ccactagaga acaggcgatc cataaaatca gattgactgc
     8461 tgggatatac atttgcccga tactgttccc aggatacatg atctttaacc gaggcagcag
     8521 tttcaacttg attgcttctg aaactagcgt aaacgaacct gtaatcaatg cttgcgaagc
     8581 aatgactgca gcgactgttg caaaagcaac gccgatcacg atccaacttt gaggcatcat
     8641 ttggaagaat ggattcaggt tcttgatttg ctgtgcttca gggttttgat aaacattcaa
     8701 caaccacgca gcctgcccaa aataattgat aaccaaacaa attttgacgt aaggccagct
     8761 cagacgaata tttcgtttgc cgacatgtcc aagatcggaa taaagcgcct ctgcacctgt
     8821 cgtagccagg aaaatatttc caagaatgaa caagcctaat ttgttatctg cactaaaaag
     8881 cagctggata gcataataag gattcagtgc acggataact gtccagtctt gactgaagtt
     8941 cattaatccc attacgccta aaaaagtaaa ccaagcgaac atgattggtc cgaatgcttt
     9001 tccgacaata tctgtaccaa agcgttggac catgaataaa acaaaaataa taactaaagt
     9061 gataatgacg atcacgttct ggttattacc gaaccggtca aaaaactgcg gaattcctcg
     9121 caagccttca atcgcagtcg ttaccgtcac agcaggggtc aataccccat ctgctagtaa
     9181 ggcagctcct ccgatcattg caggaatgat caaatatttc ccaccttttc ggacaagtgt
     9241 gtagagtgag aaaattccac cttcaccatg gttatctgca ttcaatgcaa tcacgacata
     9301 tttgattgtt gtcagtagag tcaatgtcca aaaaatcaat gagactgatc cgataacaaa
     9361 atcaggattg attcctgaca atccgccatt atcttcaaca atcgatttca taacgtaaag
     9421 cggacttgtc ccgatgtctc cgtagacgac tcccatcgct acaagcaggc cagccattga
     9481 tatctttttg gtattgtgcg ttgttgccac gtttttccct catttcttgt tatatggata
     9541 tcctttaggt aagcttgaat gatagatgat attcttatcc atgacacccg ctttcctaaa
     9601 ttgcttctaa ttatccaagt aacacactga agtgtcaact tatttgaata aaattattct
     9661 ttctttggac gttctctgat acgtcttgcc acaaatgaat aaagagcaag gcaaaaaatt
     9721 gcacccaata atgctggtat caaataaaaa ccgccgagtt ccggtcccag tggtcctagt
     9781 aaaaattcgc cgagccaact acctaaaaaa ccgataatga tatttccaga tacgcctccc
     9841 gggacttcct ttcctaaaat tgcgccagct atcaaaccta atataccgcc gataaataac
     9901 gaccataaaa aattcagcat ctcctttccc tcctttatcc atatttctca cttttatttt
     9961 acgctttatt cagaaggact ccaaaaatat gcgccaagaa actccagaaa aaaagaagtt
    10021 gtaacaaaag tgttcagctt atttccgtag aagctgcttc tggaacaccg tgaatcagag
    10081 gttgtgaaat cagcggtttg acctgagtat tagagaaaca aacggaaaaa tagttcctca
    10141 tattttgccg ttttttgagc taatatcgag ggacagctga ttgaacatcg tttattggag
    10201 aggttgtaaa aaagctgttc tgcatcaagt aataagaaca gccaagtaaa aacagctcct
    10261 aatgttttta acttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    10321 cgaaaaaaaa ggactgtgac acggcttttg tcacagtccc cttttttcga ataattattg
    10381 tccccctgtc accttcacga tcacaagtac attattccta tgaattaaat tatttttctt
    10441 catttttcgt tgaaccatct tcgttcaaca ttgcttttct tgacagattt acgcgtcctt
    10501 gtttatcgat ttcagttact ttcacaagga tctcatcacc tagtttaaca acatcttcga
    10561 ctttattgac acgatcgttt gctaattggg aaatatggac aagtccatct tttcctttga
    10621 tcaagttgac gaatgcaccg aatttttcga tacggacaac tttccctaga taaacttcac
    10681 caactttgac ttctttggtc aaatcttcga tgatcttgat agcttttttg atcatttctg
    10741 catcagctga agcaatactt acttttccat cttgatcgat atcgattttc acaccagttt
    10801 catcgatgat tccgttgatc gtatcgccgc ctttaccgat aacatctttg attttagcag
    10861 gttcgatctg gatcatttcg atttttggtg catattggct taattcttca cgtggagcag
    10921 caatcgttga agtcaattct tctaagattt ccatacgtgc ttgttttgct tgagttaatg
    10981 cttcagttag gatttgttct gtgattcctt gaatcttgat atccatctgt aaagcagtga
    11041 taccatcttt tgtaccggca actttaaagt ccatatcgcc aagatgatct tccagccctt
    11101 ggatatcagt taggatcgta tagttttcac catcagaaac aagtcccatc gcaataccgg
    11161 cgactggcgc tttgattggt acacctgcat ccatcaatgc taatgtgcca gcacagatac
    11221 ttgcttggga agaagaacca tttgattcca atacttctgc tactaaacgg atcgtataag
    11281 gaaattcttc ttctgaaggg attacttgtg ctaacgcacg ttcacctaat gcgccatgtc
    11341 cgatttcccg acgccctgga gagcctgcac gtcctgtaga accaacagaa aattgaggga
    11401 aattgtagtg gtggatgaat cgtttgctga cttccacccc taaaccatca atgatttggt
    11461 gctctcctag aggtgcgagt gtacaagctg ataaagcttg tgtttgtcct cgtgtgaaca
    11521 aacctgatcc atgtacacgt ggcaataagc tgacctctga tgacaatgga cggatttcat
    11581 ccaatttacg cccgtcagga cggatcttat cgatggtgat caattcacgt acgacatctt
    11641 tttcaagatc ttctgtgatt tgtttaactt ctttcaacaa gtgatcttca tcttcatgac
    11701 ctgcaaattt ctcagcataa gcttcgcgga tatcgatctt cacctgctcg atattatctt
    11761 cgcgagcaag tttttcttca gtcattactg ctgctttcat tgtagcgtaa gaagcatcaa
    11821 agatttcttt tttcaatact tcatcaactt gcagtaaagt cacttccatt ttttctttcc
    11881 ctactgcttg aacgatttct tcttggaaag caactaactc tttgatagcg tcaaaaccaa
    11941 acagcaatgc accaagcatg tcttcttctg aaacttcttt cgcgccgctt tcaaccatat
    12001 tgatggcttg tttcgttccg gcaacagtca attcgatatc tgtttgttct gcttgttcta
    12061 ctgttggatt caagacgtac tcgccattta cacgaccaac ttctacgcct gcgattgggc
    12121 cgtcaaatgg gatatctgag attgatagtg ctaaagaaga acctagcatt gctgccatag
    12181 ctggcgagca gtctgtttct acactcatca cgatgttcgt tacttggact tcattacgga
    12241 agccttctgc aaacatcggg cgaattggac ggtcgatcaa acgggcagtc aatgttgctt
    12301 ccgtacttgg acggccttct cgtttgatga aacctccagg gattttccct gctgcataca
    12361 ttttttcttc ataattgatc gttaatggga aaaagtctgt atcttttgct tctttagagg
    12421 ccacagctgc acttaagact actgtatctc cataacggac taaaacggct ccgtttgctt
    12481 gttttgctag ctgaccgact tcgatttgta agggacggcc gccccatgtc gttttgaata
    12541 cttgtttttc tgacataact tctccttttc cttctcgtga aagcaagacg ctactaaaca
    12601 aatgaaaact gccgaaagcc gtcttttgag cagctttcat ttggttagta ggagtccatc
    12661 tagcttgatc acggaatttt acttaattga tatacgagta aaaaaagtga gattcatgtg
    12721 aatcccactc tttttgacta aaattaacga cgcaagccta aacgtttgat caattcgcgg
    12781 taacgttgaa cgtcagtttt acgtaagtaa gctaacaagt tacggcggtg accaactttt
    12841 ttcattaggc cgcggtatga atgatggtct tttttgtgca cgcgtgcatg ttcattcaag
    12901 tggttgattt cttcagttaa tacagcgatt tgtacttctg gagaaccagt atccccttca
    12961 tggcgagcgt attcgttgat gatttcattc ttgcgttctt ttgaaattgc catttctttc
    13021 acctctttcg attattcccc tgcgactgag taaaacgttg gtgattcgct taaccaagtg
    13081 gcaggtcatg tgcctagagc acacagctat actttacctg aaaccgggtt gaaaatcaag
    13141 tagttaatca ttaagaaaag gtagttttca aacaatctta ctactacttt tccatttttg
    13201 tggtaaacta taatgcgaaa atagacttga aacacagtct tttaagaaag gggtacatat
    13261 tccatgatta caatggatga tatcattcgt gaaggaaatc cgaccttacg cgaagttgca
    13321 aaagaagttt ctcttccatt aagcgaagaa gatatctctt taggaaaaga gatgcttgag
    13381 ttcttaaaaa acagccaaga tccaatcaaa gctgaagaac tacacttacg aggcggtgtt
    13441 ggcttagctg ctcctcaatt agatatttct aaaagaatca ttgctgttca cgtaccaagt
    13501 cctgacccag aggcagatgg accttctcta agtactgtta tgtataatcc taaaattttg
    13561 agccattctg ttcaagatgc ttgtttaggg gaaggtgaag gctgtttatc tgttgatcga
    13621 gaagtaccag gatatgttgt tcgccatgcc aaaatcactg tgtcttatta tgatatgaat
    13681 ggtgaaaaac acaagattcg tttgaagaat tatgaatcga tcgtcgttca acatgagatc
    13741 gaccatatca acggtgtgat gttctatgac cacatcaacg atcaaaatcc atttgcacta
    13801 aaagaaggcg tattggtgat cgagtagaga attggcaggt tccttcgata ctatgctaca
    13861 agaaagcttt ataaaaaagg ggagtgctca aaagctgcac ttcccttttt tatgtttctc
    13921 cactaatcga aatttagata gacatctaga aatcgcaatt ccaaaaaatt ctgtgtattg
    13981 gatacgcatc ttttcttatt ttttcttatt tcttccatat gggtgtttat ctcagagatg
    14041 atagaatagt ttctaggata aaaagtagca gctacgatgt tatccttcgt agaggattcc
    14101 tgcttcagct agtttttgtt tgatgttttt cagcatatgc ttttctgggt agcggatcgt
    14161 atgcagatgg atgccgcctg ttaattcgga taacaaagta gcattacttt tttgataacg
    14221 tctcataaag gaatcgatat cttgtggcgt tttgatgtgc aaagttcctg ctaactcacc
    14281 gtaaagggga tgttccacaa ttacatcaat gatttcacca ccattttcaa cgattagtct
    14341 cagttcttct tctgtttgat cttttccatg ctggacagcg attttactga tgtgcccagt
    14401 attggtttct tctgtttcga ggatataacc tcttgctgtt gccacgatac ttttacctgc
    14461 agctcgtagt aaagcaatat cgcctacaat gatctgacgg ctgactccaa aagttttcgc
    14521 aaacttgcta gcactcactg gtttttctgt atttgccaag gtttgcatga tttgttttcg
    14581 ccgtgtctct ccttcgatca cacttattcc tccttcattt tgttttggta ttcgcgcgag
    14641 tgtttcatca aatcaacata cgtgtctgtt attgtttcct tatatccctt atttttcagc
    14701 agactaacaa ctttatccaa tacttgctgc tctctttttg catcataaac tgcttggttt
    14761 tcttcttttt tcacttgtcc tattttagtt accgtatcca ttcttttttc taataaagca
    14821 accaactctc gatcgatcat atcgatctta tgacgtaatg tttcaagaga ctcttctgtt
    14881 agttcttcct ctactgtctt gatgatacga gcaggatttc ctgcaatcac tacattgtcg
    14941 ggaaaagatt tggtcacaac cgaacctgcg ccgactacta cgttgtcccc tagagtgaca
    15001 cccggcgtga cgataactcc tccgcctaac caaacattat taccgatttt aatgggtttt
    15061 gcgtactcca gaccgctgtt acgtttcact ggatgtagtg gatgcgtcgc cgtgtaaagc
    15121 tggacattcg gagcgaacat gcagttatca ccgatttcaa tcgtgctgac atctaaaaat
    15181 gtacaattga aatttgcata aaaattctcc ccaacaaata tattatatcc gtaatcaaaa
    15241 ttgataactg gctccatata gatttttttc cctgtacggc caaaagtctc tttcaacaat
    15301 tgggatcgca gttccgctga ttctgcttgg ttgatgattt ggctttgact tcttgcaaac
    15361 atacggtcgg caaccagctc aggatcattg gcaaaataaa gctcgcctgc aatcattttt
    15421 tctttttcgg ttttgaattc agtcataatc tgctcctaat tcttgtattt ttttgaaaac
    15481 aaccgctccg tcttcttgaa taaacgtata aggctccgct aaataaacag gcgtttgatt
    15541 gattactaag attttggctg acggctggcg aaactgtacc agatcacaaa acggatgaac
    15601 ttgaaaactc gttccaacaa tgacgatcag ctctgcttgg ctgacggcat aagccgcctg
    15661 ctccatgact ccatcttgaa acccttcacc atataacacg atgtctgggc gtatttgtcc
    15721 tccgcatgct tgatgtttgt cgctgtgaag atattctttc cagtctaccg tttgttgaca
    15781 ttttcgacaa tgacattgat acagactccc atgaaaattg acgagttgcg ggcttttagc
    15841 ctttgcgtgc aaaccgtcga tgttttggga aacaacccaa acattttttt ctttcgctag
    15901 atgtgctatt tccaaatgaa tgatattggg ttttgcttca ggatgataaa tctttttgac
    15961 aaattgatag aatttatccg gttcattcac cattgcttga tgactcagca agtattccgg
    16021 ctgctccatc ccgtggtaga ttcctgacaa agatcgatag tctggcactc cagaaggtgt
    16081 ggatacccct gcaccggtca aaaatgtaat ttgctgataa gctaatatct cttttgctgc
    16141 ttcgtctact gttaattgtt tcatgttttg tcacctcact ttccattata gcccatactc
    16201 gaacaaattt attgttgaaa agtcagaaaa atgggaataa aaaagtgtta tgggcatttg
    16261 agcaatttat cacaatgttc actgacaaaa gaatgaaaac gtgttacaat actgctgtat
    16321 aaaagtgagg tgaatcgata tgttaccatt ctttatttat tggggcgtta ttctggcttg
    16381 tatcgcctgg ttagcgttaa gcgtttattt ctctgttttt tatcttgtac gcaaagaaaa
    16441 tggaaatctt tgggcttttg ctttattcaa cgtgattgcc gcaattgttt tagccattac
    16501 attagccgta tatcgaacat ggggctgggg aatcacccaa tactcaagtt tgatttatct
    16561 aatattagcc atttatggcg tcgttgttct tttgcaagcg atcctaggac gtgagccaaa
    16621 gaaagcggca gcttaaatga tcgagatgga actggacaca ggaaattttc tgttctagtt
    16681 ctttttttat tgtattacat acatttttgt gtataattat actatcgttt gcaatggata
    16741 gatgattcac attttgattg ttttttcggt aaaagtaaag atttctatat ttatcagtat
    16801 tttttcaaaa accagcagtt atagattgac aaagcctctc gagtatcgta aacttttttt
    16861 gtataaataa ctgaatacga gatgcctcaa tcaatgaggt agaggtcgcg agaatcatta
    16921 accctgtgga gtgaagcaaa catggagaag caggaatagg gaggatcgcc gaaatgtgca
    16981 cttttttgct tggagtgtat gttgggacgc aagttaagag cttgcggact gtcttagcag
    17041 tgatgctaag ttgcgctatg ttttgtgaga ggtttatcac cttatggaat tttagcggcc
    17101 tttttatatc tataaatcgg tcgcttttta ttttttcaga taaagcttta ccgcatttca
    17161 tctagaccgc tcgtgtatca tataatcaga aagggagaaa aaaatgaaaa aaaatatggt
    17221 ttcagttgcc gtactatttg cttttgtctt ctcactattc agtgtgggat ctctggcaaa
    17281 tgcagatgaa aaaacaccga gcgatgagtt tcgcgtaggt atggaggctg ggtatgcacc
    17341 cttcaactgg tctcaacaaa cagatgagaa taatgccttg ccaattcaag gccaaaatag
    17401 ttacgccggc ggttatgatg ttcaaatcgc taaaaaagta gcagatggtt tagggaaaaa
    17461 attagtcatc gtccaaacga aatgggatgg tctggctcct gcccttcaat caggcaagat
    17521 cgacgcgatc atcgccggaa tgagccctac tgctgaacga cgaaaagaaa ttgattttac
    17581 cgatccttat tacgaatcac aattagtagt agtagttcaa aaagatagca aatatgcaaa
    17641 agcaaaaagt ttagcagatc tttctggagc aaagatcact gctcagttaa atacattcca
    17701 ctatactgtg atcgatcaga taccagatgt gcagaaacaa caagcaatgg ataatttctc
    17761 agcaatgaga acagctttag cttctggaat gatcgatggt tatgtcagcg aacgtccgga
    17821 aggtgtaacg gcaactagtg tgaacaaaga cttggaaatg cttgaattca gcggtgcaga
    17881 tggcttccag acaaacccgg aagatgttca gatttctgtt ggtatgcgta aaggcgaccc
    17941 ggatatccaa aaagtaaacc agattctttc tggcatctct aacgatgaac gaaccaaaat
    18001 tatggaccaa gcagtcaaag atcagcctgc tgcaactgat agtgaagaaa aacctggcat
    18061 catttctgat ttcactacga tttggaaaca atacggcaat atgttcttac gaggtgctgg
    18121 acttaccttg ttcatcgcat tgatcgggac agttgtcggt actacacttg gattactgat
    18181 tggtgtcttc cgttcggtac ctgaatcagg aaatgcactg actcgcttct tccaaaaaat
    18241 cggaaatgca cttctttcta tctatgtcga agtattccgc ggaacaccga tgatggtaca
    18301 agcaatggtc atcttctacg gtctggcact cgcttttggc atttcattga accgaacgat
    18361 tgccgctttg tttattgtct ctctcaatac tggagcttac atgacagaga tcgttcgtgg
    18421 ggggattttt gcagtagatg aagggcagtt cgaagctgcg caagccattg gtatgaccca
    18481 tggccaaacg atgagaaaag ttgttattcc acaagtttta cggaatatct tgccagcaac
    18541 aggaaatgag tttgttatca atatcaaaga tacagcagtt ttaagtgtaa tcggcgtagc
    18601 tgatttgttc ttccaaggaa actctgcttc cggtgcgaat ttccaattct tccaaacatt
    18661 tacgatcgtc gggatcatct acttagtcat gacctttacg atcaccagaa tcctgcgggc
    18721 ggtagaaaag aaaatcgatg gtccttcagc ttataccaag cttgaagaaa tcgacaattc
    18781 aaatttgcag gaataaggag gaagaatcat gaatgaaaaa attattgaaa tcaaacatct
    18841 aagaaaaagc ttcggtgaaa atgaagtatt gaaagatatc agcgtaacag tcaataaagg
    18901 tgaagttgtg acgatcatcg gttcttccgg ttctggtaaa tctactttct tgcgctgtat
    18961 caatttactg gaaaaaccaa caggcggcga gatcatttat aatggagaaa atgtattagc
    19021 tcctaaatat aatttaccta aatatcgaac gaatctaggt atggttttcc aatccttcaa
    19081 cctgttcaac aatatgaatg tcttggaaaa ctgtatgtct ggtcaaacaa ctgtcctgaa
    19141 acgagataaa gaaactgcca aaaaagtagc aatcgaaaat ctggaaaaag ttggtatgga
    19201 tcgttatatc gaagccaaac cagcacaatt atctggtgga cagaaacagc gtgtcgcaat
    19261 tgctcgggca ttatcaatga atccagatgt attgctattc gacgaaccta cttcggcgtt
    19321 agaccctgaa atggttggcg aagtgcttaa tacgatcaaa gacttagcac atactggctt
    19381 gacaatgctt atcgtgacgc atgagatgga atttgcaaaa gatgtatctg accgtgtcat
    19441 ttttatggat aaaggtgtga ttgcagaaga aggtacacca gaagatatct ttgtccatcc
    19501 gaaagaagaa cgtacaaaag aattcctttc acgtatttta aatgcttagg atcaatagct
    19561 gattgggaca aagagctgcg gtgtttaccg cagttctttt ttatgaatta ctcataaaag
    19621 gtaaatttct gaaa
//
LOCUS       DADVXE010000050        19565 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.051, whole genome shotgun sequence.
ACCESSION   DADVXE010000050 DADVXE010000000
VERSION     DADVXE010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19565
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.051"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(541..1566)
                     /locus_tag="KB913_001959"
     CDS             complement(541..1566)
                     /locus_tag="KB913_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6820301.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            1841..3526
                     /locus_tag="KB913_001960"
     CDS             1841..3526
                     /locus_tag="KB913_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBB6820302.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            3540..4823
                     /locus_tag="KB913_001961"
     CDS             3540..4823
                     /locus_tag="KB913_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBB6820303.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            4893..5762
                     /locus_tag="KB913_001962"
     CDS             4893..5762
                     /locus_tag="KB913_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6820304.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            5759..6595
                     /locus_tag="KB913_001963"
     CDS             5759..6595
                     /locus_tag="KB913_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6820305.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            6621..7688
                     /locus_tag="KB913_001964"
     CDS             6621..7688
                     /locus_tag="KB913_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBB6820306.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            7685..8512
                     /locus_tag="KB913_001965"
     CDS             7685..8512
                     /locus_tag="KB913_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBB6820307.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            8557..9582
                     /locus_tag="KB913_001966"
     CDS             8557..9582
                     /locus_tag="KB913_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6820308.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            9579..11762
                     /locus_tag="KB913_001967"
     CDS             9579..11762
                     /locus_tag="KB913_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBB6820309.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            11762..12892
                     /locus_tag="KB913_001968"
     CDS             11762..12892
                     /locus_tag="KB913_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6820310.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            12889..13566
                     /gene="pgmB"
                     /locus_tag="KB913_001969"
     CDS             12889..13566
                     /gene="pgmB"
                     /locus_tag="KB913_001969"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBB6820311.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            13650..14177
                     /gene="msrA"
                     /locus_tag="KB913_001970"
     CDS             13650..14177
                     /gene="msrA"
                     /locus_tag="KB913_001970"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6820312.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(14378..15064)
                     /locus_tag="KB913_001971"
     CDS             complement(14378..15064)
                     /locus_tag="KB913_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBB6820313.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            15144..16682
                     /locus_tag="KB913_001972"
     CDS             15144..16682
                     /locus_tag="KB913_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBB6820314.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            16802..17269
                     /locus_tag="KB913_001973"
     CDS             16802..17269
                     /locus_tag="KB913_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBB6820315.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            17788..18231
                     /gene="rplM"
                     /locus_tag="KB913_001974"
     CDS             17788..18231
                     /gene="rplM"
                     /locus_tag="KB913_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBB6820316.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            18247..18639
                     /gene="rpsI"
                     /locus_tag="KB913_001975"
     CDS             18247..18639
                     /gene="rpsI"
                     /locus_tag="KB913_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBB6820317.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(18727..>19565)
                     /locus_tag="KB913_001976"
     CDS             complement(18727..>19565)
                     /locus_tag="KB913_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6820318.1"
                     /translation="ISDELTKKSKEYANIKIIKGYVRSMFDIAEILNYIEFNRTTKII
                     QSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLLTFHDYTLFMITLYL
                     GDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTVIQVPEVVMTLLSEW
                     KSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRINSIKRRHPDLVHLS
                     PHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIVDKAVFEAFQRGLNK
                     CD"
BASE COUNT         6336 a         3532 c         4150 g         5547 t
ORIGIN      
        1 gtctaaaata atttgtctaa ctagaagaaa agtgggaaag gatcttaaca acatcggttc
       61 gtatccaatt aaggtatcgg aacgatcatc ttccaagaga agtcaatcaa caaaagtaaa
      121 gatagatcat tttttgaatg caaaataaat tgatgggaag atagagcggt tatttttaat
      181 attttgctag ctattattga ataattcctc gaataaaaca aaaccagtag acatgtctgt
      241 tattctattt atgttttaga gataagtatc cccaaataac atggattgaa ataagggtaa
      301 atgtgtttaa aaaaacgaac tataaaaact tatacacaac gtggttaaaa atagtttttt
      361 cttccctgtg gaaaaaatag tttaacacaa acattatagt tatccacagc tatctaaaac
      421 agatggaaaa taagaaaaat tcgctaaaat accgggaggg ggtaacgagg gatgagtgat
      481 tgaaaaaaga acagagtaac tgacttatcc tcagtgtttc tgttctttta taattctgtt
      541 ctacatttct tgttgttgga tcgaatctgt gagagtaatc tcggttgaaa gaatgattct
      601 tttttcttca gggtattggt ggtggattag ttggaataaa agttctgtgg ctttgattcc
      661 taactgattt gtcggaatgt ctatccgagt caactgtggc gaaaataggg aggacaataa
      721 gggatcactg aatcctgcga tcgaaagatc atcaggtatc tgctttccag attgttctgc
      781 cactttgtaa atactcaatg attttaatgc atcggtagaa aaaatcgcag ttggtctttc
      841 tcgtagcttc attaaatcat tcattgctgc catgctatct tctaagcgaa agccgccgtc
      901 tataatccat tcattacgga tatctaggtg gtgatcaaat aagcattgac ggtaaccatt
      961 gagacgatca ttggatacat aaacttctgt cggagcatgg agacagccga tatgacggtg
     1021 tccattcttg atcagtgttt ccaccaaatc gtaactatcc tggaaattat ccgtgtccac
     1081 tgagtagatg ttcgtgtagt cgtttccgac ttttccgatt accacaatag gaatattgta
     1141 ttgatccaat tcaaaaagaa gtgtttcatc catcgtagag cttaaaataa taattcctcg
     1201 gatcattttt tcttggatct ttttcgcgca tttttctagc tcttcttctg gtgtttttgc
     1261 cgtttgtaga atcaagtcga agttattttg ttcagaaacg gcagaaatgg attgaataac
     1321 atctgaaaaa aaaggattgc cataggtcgt atgagaagta cgatgagata atgctagaat
     1381 cgcgtcaaaa ccatttcctg acagtcctct tgcaattttg ctcggttcat aattcaattc
     1441 tttgattgct tgaagtacac ttgcttttgc tttatcagag atatttggct ggttatttaa
     1501 tactctggag acagttgatt ttgagacatt agcttttttc gcaatgtcat aaatagtagg
     1561 tttcaatttt atatgcacct cctttttggg agcgttttag aataattcca tagtacaata
     1621 gacattcttt tttgtctatg attttgaaaa tttaggaata gcttgcatga tcatgagaga
     1681 ccatattttt ttaagaagct attaattatt gatacataag ctttcttatt tgtatttttg
     1741 tgtatatcaa aattatttaa aaaaatgcta ttgacagtaa gcgttttcca taatatgatc
     1801 aaatcgttgg gaacgctccc aaaaaagaaa ggggaatccg atgtatacaa aacttttaca
     1861 agcgatttat cgcgactcag atttgtctga gaaaaccgcc tctatgattg aacaaaaagt
     1921 cagtgtttat cagcagaaga aaggccaggc aggcaaactg cattgggacg aagaagatat
     1981 tttcttgatt acttatgggg atcaattttt tgaagagcag caaccaactt tgcgtacatt
     2041 taagaaattt tatcaaaagt atttggcaga tacatttaga gttgtacatt tcttgccatt
     2101 tttcccatat acatctgatg atggtttctc cgttgtaaat tatcaggcaa tcaacgaccg
     2161 tttgggcaca tgggaagata tagaagaaat gagaagcgaa acacggttaa tgttcgactt
     2221 tgtctgcaat catatgtctg ccgaaagtac ttggtttcag gaatatttaa acttgaatga
     2281 tacgtacaaa gattttttta ttgatttgcc actggataca gatacaagca gcgtgactag
     2341 accaaggacc agcccgttac ttacaacgtt cattgacaaa aacgggaaag aaaaacacgt
     2401 atggacgact tttagcgaag atcaagtaga cttgaatttt aaaaatccag aagttttatt
     2461 gaaaatgatc gatattcttt tgttttactt agaaaaaggc gcttcattta ttcgcttgga
     2521 cgctgtggga tttttatgga aagaactagg aacttcttgt atacacctgc cagaaacgca
     2581 taaaatcatc caattattcc gtgcaatcgc tgatgaagca gctccaggaa cggtattgat
     2641 cactgagaca aatgtgccac acaaagataa tatcagttat tttgggaatg gcgagaatga
     2701 agcacagatg gtctatcagt tttcgctacc acctttgacc cttcaagcga ttcgttcggg
     2761 taatacaagt aagttgaaag aatggttaaa aaccatcgat ttcgcatcga aaaaaacaac
     2821 tttttttaat tttttagcct cccatgacgg tatcggattg aatccggtac gaggtattct
     2881 gccggaaaaa acgatccttg aattagtgga acagctgaag aaagagggta cccgagtaaa
     2941 ctacaagaaa aacccagatg gaacgaccag tccatatgag ataaacgcta cgtatctaga
     3001 tgcgttaagt tctccaacag atacgacgga atggagaagc aaacgctttt tagctgctca
     3061 ttcatttttg gtaacgttac caggcgtgcc ggcaatttat attcaaagtg tgctgggaag
     3121 tcgaaatgat tacaaaggcg tagaaaaaac aggagagaat cgaaaaatca atcggcaaaa
     3181 atttttgtta gcagatattg agaaagagtt gcagacagat ccattaagaa cagcagtata
     3241 tggtgaattg acccagatgc tatctattcg aaaaaaagaa aaagccttcc atccgaatag
     3301 tttgatttac ttactggact cagcagattc ttttatcagt tttattcgcg aagcgaagga
     3361 agagaaagtc ttagttatcc ataatttttc caatcaatca gcaggttatc ttttaccaaa
     3421 aggagattac ctagacctgt tttctggaca aattatccat tgcagtcaag aacgaaagtt
     3481 gatattccag ccgtatgaat atatgtggct gaaaataata aaataagagg tggaaaaaaa
     3541 tgaaaaaaat tattgttact acctgtctgc tagctactgg atttcttctt actgcttgtg
     3601 gtgaaagtca aagctctaac gaatcacaac agacaacgat tcaattcatg cactcttctg
     3661 tcgaacagga acgattaagt gtgatcaatg aactggttgc tgattttgaa aaagaaaatc
     3721 cagacatcaa aatcaagcaa gtgccggtag aagaatcagc gttcaataca aaaatcgtta
     3781 cgttagctcg ttccggtaaa ttaccagaag taatggaagt cagtcaggat tttgctaaag
     3841 tgatggataa agatgaactg attgatcaga cggcagtcca aaacgttatc gaggaagctg
     3901 gagaagataa ttattatgac ggagccaaaa accttgttcg ttcagaagat ggaaaaagct
     3961 atattgctgc accaattagc ggctgggttc aaggtatttg gtatgacaaa gaaaaattat
     4021 cagaagctgg tttttcagaa ccagaaaatt gggatgatat tttaaaaatt gctcaacatt
     4081 tcacagataa agagaataaa caatatggaa ttgctatgcc tactgctgaa ggaacaatga
     4141 gtgagcaagc gttctctcaa tttgctttgt caaatggagc aaatgttttg gatgatgaag
     4201 gcgaggtaac gatcgatacg gaaaagatga gagaagcatt gtcgttttat caaaacttat
     4261 cccaatacac gatgccaggc tctaatgatg tgacagaaat caaagatgct ttcatgaatg
     4321 gaacagcacc aatggcaatc tattcaactt acattttgcc ttctgtttat gaagcgggga
     4381 actcagaaaa tatcggtttt gctatcccaa cacaaaaaga tcaagctgtc tatggcacag
     4441 tatctggatt gacgatttct tctggtctag acgagaaaca aaaagaggct gctgaagcat
     4501 tcacagcttt cttatctcaa ccgaaaaaca tggaaaagtg ggtcttgatg tctcctggtg
     4561 gtgctcaacc agtgaataaa caagtagtcg aactggatgg ttacaaagaa aatgaagtca
     4621 tcaagtcttt tggcgagctg ccatctgaga ttgctagtgc ttttgatgaa gtacaagtct
     4681 ttggactagt cggggaaaag aatttcacga aaatgggaga tatcacaagc tcaggtgtga
     4741 tcggaaaagc agtgaaccaa gtaactgtcg gaaacgaaga tgtcgatcaa gctttagctg
     4801 acgcacaaaa aaatacgaaa taacaagaag ttctgccaat ggtgttcgaa aaaagtagat
     4861 agctattggc agattatcag ggggaggttt caatgaatcg tccaaggaaa cattctgact
     4921 taaaattagc catgggactt ttagcaccaa gcatgctttt attagctgtt ttagtgctga
     4981 ttccaatgct ttccaatatt cagatcagtt ttttcgatat gccgctgaat cctaactcag
     5041 acgccgtttt tatcggatta agcaattatc ttgaaatttt aagtgatagt gaattttatc
     5101 gttctttagg tttaacagtt gcttacacat tcttagttgt agcaggcagt acagctttag
     5161 gattagccgt agctattttg cttaaccgca agttcagatt taggaaaacg gtgcgttcac
     5221 tgattttatt aagttatgtt acgccatcta tttctttgat ttttgcttgg aaatatatgt
     5281 tcaataatag ttatggaatc gtcaatgatc tgttagtaga taggttgcag cttttcaacg
     5341 aagcaccgct gtggttcgac cagccagttg ctagcttctt tatggtcgtt ttgtttgcta
     5401 tctggagata ctatccgtat gcgtttattt catttttggc tattttgcaa acagtcgaca
     5461 aaacgcttta tgaagcagct gaaatggacg gtgcaaatgc ttggcagaag ttcaagatcg
     5521 tgacactgcc ggcaatcaaa ccagtactag caactgtgat tgttttacga tctatctgga
     5581 tgttctatat gtttacagat gtctatctac tgacgaataa agtcaatatc ttaggcgttt
     5641 atttgtatca gacagccttt gcgttcaatg atcttggaaa agcagcagct atatcgattc
     5701 tattgttcat cattattgca gcggtcgtct tgctctcacg aaagaaggtg gacttgaaat
     5761 gaaaaataaa aagagcagga aaatcttatt ttacgcgacg attttgttgc tattagctgt
     5821 caatttgttt ccatttttga tcatgctgat gacatcattc aaggattcac aagaagcaat
     5881 tgcaacgaca caaactattt ttccgaaaga atggactttt gaacattatc aggatatttt
     5941 caatgctgag atttttccat tcatcatgta tttcaaaaat agtttagtga tctccttgat
     6001 agcctccgta actgcagtag tgattgggat cagcggggca tacgctttgt caaaactacg
     6061 cttcaaagct cgctcgaaaa tcaatgctag cttttacacc gtttatatgt tttccggtat
     6121 tttgatcgtt gttccattat ttaaaatcat ttccggtcta ggtttgtatg ataccaatac
     6181 agcactgatt atcacgatgg tcgttcaaac acttcctact gcgatattca tgctaaaaag
     6241 ttattttgac acgattccga ctgatattga agaagcagca atgatcgatg gtcttagccg
     6301 gatccagatc attattcgga tcattatacc attggctatt tctggaatca tttctgtctt
     6361 cgtttattgc tttatggttt cgtggaatga ttatttattt gcttcgattt tcctgtcgac
     6421 ctccgaaaaa tttactttac caatcggttt gaacacatta ttcagtacac cagactacat
     6481 ttggggacga atgatggccg cttcattggt gaccgcttta ccagtcatca ttatgtatgc
     6541 gttatctgaa cgatttatta aaggtgattt agtcgaaggc ggcgtaaaag gataaaaaga
     6601 aaagaaagag gaaagaaaag atgaaaaaat tagttgcatt agaaccaaga atagccggat
     6661 tcaaagatta cgaagaccgt gagatcgaaa agaacgaagt acgtatccga gtaattttcg
     6721 ctactccaaa accaggaaca gaaattgtcg actttagagg attaagtcca tttatcgatg
     6781 aagaattttc agaagaatgg cgcctattct tgccaagaga agaaggaagc caacgcggtg
     6841 tggtatttgg cgaatttcaa ttaggaaata tgattgtcgg tacgatcgaa gaaacgggca
     6901 gtttggtgac agagtatcaa aaaggagagt tagtctgcac ttatggaccc attcgtgaaa
     6961 cgctgattac aaacggtgtt gataattata aactacgtaa acttgatcgg ttggatcaat
     7021 ggaaaaatgc agtatgttac gatcctgctc aattcgcttt aggtggtatc cgggaagcac
     7081 atgttcgagc aggtgatgct gtagcaatct tcggtttagg cgctatcggg caaattgcga
     7141 ttcaattagc taaaaaagca ggtgctacta ccatcgttgg gatcgatccc atagcgcagc
     7201 gtagagaatt agcagaaaaa tacggtgccg attacacgct agatcctatg aaagcagatg
     7261 tcggttttcg tctaaaggaa ttgacagata aacgtggagt agattcagtt attgaaacga
     7321 gtggcagtgc tgccgcatta caagcttctt taagagggat cggctatggc gggatcattt
     7381 cttatgttgc ctttgctaaa ccttttccag ctgggtttaa tcttggtcgc gaagcacatt
     7441 tcaataatgc aaaaatcgtc tttgctcgag catctagtga accaaaccca gattacccaa
     7501 gatggaaccg taaacgaatc gaggacacat gttgggaatt attgatgaac ggttacttgg
     7561 attgtgaaga aatcattgat ccagttgtgc catttgcaga aagcgcagaa gcttacatgc
     7621 gttatgtaga ccagcaccca gaagaaagta tcaaaatggg cgttcaagtc cgaggaggag
     7681 aacaatgaaa ttcggtacgc aagatcaagc atttttccca agagacattt tagaaaaatt
     7741 tagatttatc aaagactgtg gatttgaaga atacgaaatc gacggtaagt tgttaataga
     7801 aaatatcgac acagtcaaac aggcaatcaa agaaacaggg atcccagtag tgacagcttg
     7861 taacggctac gatgggtgga tcggtgactt tatcgaagaa cggcgtctta atggtgtacg
     7921 tcaaattgct gagattttgc gtgcactaag cgaggttgga ggcaaaggaa tcgttatccc
     7981 agcagcttgg ggaatgttca cttatcgatt accgccgatg gtttcacccc gaagcaaaga
     8041 aggagactat aaagcagtca gcgaatcact tcgttattta gataaagtag ccgaagaaac
     8101 aggtacggtt atttatttgg agcctttgaa ccgataccaa gaccatatga tcaatttgtt
     8161 agcggatgcg cgtcattaca ttgactctaa tcaattgaaa catgtgcaga tcatcgctga
     8221 tttttatcat atgaatattg aagaagatga tatttcaaaa gcattgacta cgcaaaaaga
     8281 gtatgtgggt catatccatt tagcagataa tcatcgctac caaccaggat ctggcgcaat
     8341 tgattttact cgccattttc aaacgctact tcaaaatgag tatgaaggtt atatggtata
     8401 tgaatgtcgt ttgcgaggag aaaatgaagt gaaaatttat caggaatcat tgcaatactt
     8461 gaaaaactgt ctggaaacag cgcgtcattt aaatgattta gagaaagaat agagaaagaa
     8521 taacaataag taaataagca aaggagggag aaataaatga agaaagtagc aatcataggc
     8581 gctggacaag tagcagaaaa agtacatgct gcttattatc aaaaaagatc agatgtctta
     8641 gaattggccg ctgtggttga tccagtcagc cagcgagcag aagacttttg ccgacgtaca
     8701 ggattttctc atgcgtatac atcagttaca caaatgctga atgagatttc tcccgatatc
     8761 gtgagtgtct gtacacccaa tcgctttcac ttcgaacatg tattggctgc cctcgaagct
     8821 aatgcttcag tgatgtgcga gaaaccacca gctatgacag ctgatcaagc aagaaagatg
     8881 gcagagacag ccgataaaaa cgggcagatt ttggcttatg gattccagca tcgtttttct
     8941 gacgaagcaa caatgatcaa gaatcatctt gatgttctcg gggatattta ttacgtagaa
     9001 gcgaatgcgc ttcgtcggtc tggtgttcca ggctggggaa cgtttatcga caaagaactt
     9061 caaggaggcg ggcctttgat cgattatggc attcacatgc ttgatacagc gatgtatatt
     9121 actggatttc ctaaagtaaa aagcgttcgg gcgtacagct tccaaaaaat tggtacgaaa
     9181 aaaaattcag ggaaattcgg gaaatgggat ccaagcaaat tcacagtaga agatgcaatt
     9241 tttggcacac tggaattaga aaacggcaag atcatccaac tgaatacttc gtttgctttg
     9301 aatatcagag aagacaaact gaatgtggct ttttgtggcg atcaggcagg tgctaatctg
     9361 tatccaggcg aactattcga agatgtagat ggaaagctgg tttccttaca aaagaccacg
     9421 ccagttaatg acccacatga actaagtatg gctcattttg tgaatcgggc gctcggtgac
     9481 cagactcaga tgattgcaga tggctggcaa ggatatgtca tccagaatct ggtggaaaat
     9541 ttatatcgtt cggcagaaac aggagaagtt attaccttat gaaagtagaa gaaaaacagt
     9601 ttgatttaga gtatatcaat aagtatgcga gtcagatgac cattggaaat ggattttttg
     9661 gtatcagagg aagccaggag gaagactatc ggaatcaagt aaggggaatg tttgcagctg
     9721 gtgtatataa ccgaccttta ggagcagaat cagccgagtt agtgaatctc ccagatgtca
     9781 tcagatggga aataaaaatc gacggtgaac atttttctct tgagacgatg aaagttcttg
     9841 catacgagcg ggcactagat ttagaaatgg gagagcttaa acgctatgcg ctcattgaaa
     9901 ctgctcaagg aaaaaaagtg gaagtcatta cttgtcgtgt tgctgatcaa aataatctcc
     9961 atcaggcagc cctgaaagtg gtcatcaagc cgttgaccga agactgccaa gtagatgtga
    10021 aaacgggtat cgatggacag caaaccaatt ttggtacaca gcagttggtt gaaaaagaac
    10081 tgcgagtatt tggtgacgat ttgatcagtg catcctacca gacaacagaa agtaaaattg
    10141 atattgggat tgcagctaaa ttcaataaag caggtgtatt ccaagcaaaa aatcgccgga
    10201 tcaccgcttc cttttcagaa aagatcagaa aaaatacgtc ctttacgctg gagaagatca
    10261 tcgtgctctc tacctctctt cagcaaacag acccgtttaa gaaaagtatt gcccaagccc
    10321 agaaaagcgt tagttataca gaaattttag agcagtcgat gtcttattgg acagattttt
    10381 ggcatcagca tcggataacg atccaaggcg attcttcttt cgatcagtta gcgatggact
    10441 tcgctgctta ccatttacag attatgactc cccgcaatga tccaagtgtt agtgtagggg
    10501 cgaagggact aactggcgaa ggttataaag ggcatgtttt ctgggatacg gaaattttta
    10561 tcctgccttt ctttttatat cagtttcctg aagtagcaaa gaatttgctg ctgtaccgtt
    10621 atgatcgatt agaaggcgca cggcaaaaag caagagatta tcactatcaa ggtgcacttt
    10681 tcccatggga aagcgcacac actggtcagg aagagacacc caaatttgct gcattgaata
    10741 tcaaaaccgg aacaagacaa gaagttgctt cagctgccgc agaacatcat atcagtgcag
    10801 accttgctta tgccgttcaa gagtatgtcc aagcaacaga ggatcaatcg tttttagaaa
    10861 caaagggaaa aacgctcatt catgaaacag cagctttttg gctgagcaga gctgtaaaag
    10921 tcgatgatca tttagagata cacagagtca ttggtccaga tgaatacaca gaatatatcg
    10981 acaataatgc atatacgaac tatctggcgc attataatgt ggccttagct gttaaatatc
    11041 aagctggcga tccgcttttt ttgaaagaat gtcaaaattt tttagataag ttatatttgc
    11101 cagtgcctaa caaagaacag ctgattccgc aagatgacac gtatctcagt aagccagtta
    11161 ttgatttgac cacttacaaa gaacgtcctg gcagccagtc tattttactt gattatgccc
    11221 gtagcgaagt aaatgaactc caagtcagca agcaagcaga tcttgtcatg ctgttatact
    11281 tattacctga gtatttttct caaccaatcg tttctaagaa tttgcattac tatgaaaaca
    11341 aaacaatcca cgactcatcg ttgagtaaag cgattcacgc catagaggct tgccgtatcc
    11401 aagaaatgga atgggcgtat catttattcc aagaagcgtg cctgattgat ttaggaccag
    11461 atccgcattc atcagatgac ggaattcatg ctgcttcatt aggagcacta tggctagcag
    11521 ttatatttgg tttttcaggt attacagtaa cgaatggaac tctttctatt tctccaagac
    11581 ttccttcagc atgggaaaaa atttcttttc cttttatttg gaaaaatcac aggttgctat
    11641 ttgttttgac aaaaaaacaa atagtaataa aaaaagagac gaaagaaaca ttacctattt
    11701 ttgtcaatgg agaccaatac cagctggaaa aagaactgat cttggaacgg aggggaaaat
    11761 aatgcgtatt ctgattgcgc cagattcttt caaagaaagt ctgacagcct tagaggcagc
    11821 acaagccatt caatcaggtt ttcaagaagt ttttgttcag gctgaatatg atctgctacc
    11881 tataggcgat ggaggagaag gaacggtttc atcattagca gacagtttaa ggttgaagcg
    11941 gcaaacagca gtcgttacta atgcatttgg caaaaacaaa gaaatccagt acgcttcaga
    12001 cggtcaaact gcgatttttg aaatggcaga aatcgtcgga ttgaaagatg tcccactaaa
    12061 ccaacaacag ccacttaggt tatccacgcg aggagtagga gaactgatac gacaattgtt
    12121 gcaacaaggt gttcgacaca tcatcatcgg cgttggcgga agtagtacca acgatggcgg
    12181 catcggcatg gcagaaggtc taggttatgc tttttacgat caagataatc aaaaagtaga
    12241 agcactggga gaaaatctag gtaaaattgc tacagttgat aaaacgaacg tgcctattga
    12301 gctgattaaa gccaaaatca ctgtcattac tgatgttact aatcttttat gcggaaaaga
    12361 aggcgcttct tttgttttcg gaccacaaaa aggcttgaaa gaaaatgaat tagcagtggc
    12421 tgaccaagcc atgcatgatt tttatatgag atttgcccct caagtaatcg aggcatcggg
    12481 cagtagtgct ggtggtggaa tgggtgcagg actgttagca tttgcttcag ggaaaatagt
    12541 ctctggcatc gactacgtat tggatttact ggagttcgat aaacgggtac agcaagcaga
    12601 cctcgtaatc gtaggcgaag gacgtctaga tggacaaagt ctaaaaggaa aagcgccagt
    12661 tgggattgct agaagagtac cagagggcgt tcctgtgata gctatttgcg gaagtgttgg
    12721 taaaggaagc gaaaaagcag cagatgttgg catttcggcc gtttttccga tccttcctgc
    12781 agctgtgcct ttacaagaag ctttacagca agccactgat aatcttcatc gcacagctaa
    12841 aaacatcgca tctttacttc aagtcgttca ttttcaagga ggtaatcgat gaaaatcaaa
    12901 gcagcactat tcgatttaga tggcgttctt gtagacacag ctcgttatca ttacgaagcg
    12961 tggctggttt tagctaacca gctgtccatt ccattcactg agaaagaaaa cgagcaactg
    13021 aaaggaatat ccagaaccga gtcactagag cgattgctgt catttggaaa aatggaacag
    13081 aaattctcag aaaaagagaa atcagccttt gctgagcaaa aaaacaatct atatcttcaa
    13141 gcgattcaaa aaatggatga aacatccgtt ttgcctggtg caatagctgt tcttgagtac
    13201 ttgaaaaaaa caaacatcaa gatcggattg ggatcagcaa gcaaaaatgc acgcctcatt
    13261 ttagaaaaaa cgaatttgac aagttatttt gatgtcctta ttgacggcac gcaagtatca
    13321 aaagcaaaac ctgatccaga agtttttctc aaaggagcac agcaattgaa tgtaccgcca
    13381 aatgcatgct tggtcattga agattcagaa gctggttgtc aagcagcttt ggctggtaac
    13441 atgcatgtat tgggaatagg tgaaaacata aatcttcctt ctgctgaata tgtgattcct
    13501 gatttaaccg tttttgatca agtacgttcg ttttggcatt tatcagaagc cgtatcacgt
    13561 atataatagt ttccgttttt tctgtcacaa gcaaaacgtt atcctccttt tggaaatcaa
    13621 ggtatgatga gaaaaaaggg ggattttata tgacaaaaaa agcagttttc gcaggcggat
    13681 gcttttggtg tatggtcaaa ccatttgaag agcagccagg gatcatttct gtgacatccg
    13741 gttatactgg cgggcatgta ccaaatccaa cttatgaaca agtaacaaca ggcacaacag
    13801 ggcatacaga agcagtagag atcgaatatg atccagaagt tatttcttat gatcagttgg
    13861 tggaaatcta ttggcagcaa accgatccga ctgacgcatt aggacagttc gctgatcgcg
    13921 gtgattctta tcgtccagtg atctactata atgatgaaga agaacgaaat attgcagagc
    13981 gttcaaaaca agcattgcaa gacagcgggc gattcgataa gccaatcgtg acaaaaatcg
    14041 aaccaagaag cgaattttat cctgcagaag attaccatca ggattattac aagaaaaaca
    14101 agctccatta caatctttat cgagaaggtt ctggacgtgc aggtttcctt cgtcgacatt
    14161 ggggcgtcaa gaaataagaa gccgaaaaag ctacttatgg aacaccgtat atcagaggtt
    14221 gtaaaaccag cattttgagc taatactgag ggtcagctga ttgaacacca tttagtggag
    14281 aggttgtgaa cctgtcgcct agctccaagt cacaaggatt tggtaagaga acactatata
    14341 tcagaggttg tgacaagtcg tttgtcacaa ccttttttca atacctaaga tgaaggacaa
    14401 tcagcaacgc actgctcaaa aaaggaatga aaggcagctt ttccaacttt tttttatgac
    14461 agataaagta aacagaaaaa acggatattc caaacagact agcaagaaac aagatctgaa
    14521 gcaactcttc tagagacaag ccaccactcc aagaaagcat caacagagta tcgccagctc
    14581 cgagatagga ttgaccatag cgaaggcaca caccgcctac gataaacgtt aacagcacac
    14641 tttgccattg gaagacgccg gcctgcaacc aaaaaatcca taaaattgcc caagaacaga
    14701 atagcgtgtg agaatggacc atgaagtaaa ataaatccat caacgaaaat agcaaagccg
    14761 aaagcatcca tatgaacgtc gaaaaatttc ttgcggaaga aaaagtaaag aaccaggcaa
    14821 aaagaccacc acataaggct tctgccaaca aatagtagaa gggcaaccga cacctgcaat
    14881 agcggcagcg aaatcgttgg acgatgatcg agagaatcgg aatcaattca taccaagaaa
    14941 gcgaacgaca gcatttgaca caatgagatc taggataaat aatagagtga cctaacggaa
    15001 tccgctgggc ggttaaacat aaaaatgatc cgatacagca accaatgata aaataaagta
    15061 acacgccatc tccccctttt caaaaccaag atacgcaagc ttaaactaaa tttttgtaca
    15121 tacataaaat ttgaggtgaa aaaatgaacg tttcaatcgg attagatatc ggaaccacac
    15181 aaaccaaagc agttgctttc acagatgaag cccaagaagc agcatccgct tattttcgct
    15241 accctttgat ccaagaaaca caagggatgg cagaacaaga tcaggaattg atctttcaag
    15301 gtgtctgcac cgttataaaa gaagtaatta aacagttgcc ttcagacaca atcattcaat
    15361 ttgtctcctt ctcctctgcg atgcatggcc tgatattgtt ggatgaagag aaaacaccgt
    15421 tatctcgaat gatcacttgg gcagataacc gagcagcgga cgaagcagaa aaactgaaat
    15481 ataccgtgct tggcaaagaa ttttatcggc agactgggac gccgattcat ccaatgacac
    15541 cattgaacaa aatcaagtgg ctgcaaaaca gccaacctga attattcaaa aaaactgctt
    15601 attttgtcgg tatcaaagac tatatctttt atagattgtt tggcgaactg atcagcgact
    15661 acggaacagc ttcaggaact ggatattttg atatccatga attccaatgg gcagaagaag
    15721 tgcttgacta cttgaacatt cgaatagagc aattgccgca agtctttcct tccacctatc
    15781 aagtaacagg tctaccatca aaaacagcag cagaactagg tttgccaaat gatatatcat
    15841 ttgttttggg aggggcagac gggccgcttt ctaatctagg gttaggtgct tttggtgata
    15901 cgatcgccgc tttgaccgta ggaacgagcg gagcacttcg ttttattact actcagcctc
    15961 agttccatcc agaaatggag acgttttgtt atgttctgga tcagaaacat tgggtagtgg
    16021 gaggagcgac tagcaatggt gctggcatct ttgattgggc agggcataca tttttacagg
    16081 aagtcgttca atctgctaaa gaaaaaggag aaaatccata tgatgcactg ctttcggcta
    16141 tcgcttttgt gccagcgggt gccaatggtc tgatttttca tccctattta cttggtgagc
    16201 gagcaccgct ttgggacgca gatgcgtttg gcagttttat cggtttacag cggcaacata
    16261 cagaaaaaga aatgatgaag gcgattctag aagggatctg tctcaacctt tatcggattt
    16321 taaaaggagt ttgccaggaa aatcagctca cagagatccg tgctacaggc gggtttgctc
    16381 aatctccgat ttttcgtcag atgatggctg atgtactggg ttacccgctt gttttcccta
    16441 ctgtcacaga agcatccgca ttaggagctg tgattttagg ctggagaagc atcggaaaga
    16501 tccaaagtat cagtgaagca caggaattga tagaattgaa agagcaagtt ggagtacaag
    16561 aaactgatca taaaaaatat cagaaaatct atccattatt tgtttcgaca caaaagcatt
    16621 tagcacagac ttatcagcaa tttgctcaac tgcgagaaga attagctgat tctgaaaaat
    16681 gattggcttt acggataaaa aagcgaactg aaaatcgttc tcaggtaaat gattttgttg
    16741 tacttttcat tgaaagtcta ctattatttt aagtgtaaga aaatgttagg aggcaagaaa
    16801 gatgaaattc caacaaacca aagaagtatt aaatcaatta gttgcagatc taagccaaat
    16861 gtctgttgtt gttcaccaaa cacattggta catgagagga ccaggtttcc ttacattgca
    16921 cccaatgatg gatgagttca tggatgattt gaacgctcag ttagatgaag tatccgaacg
    16981 cttgatcaca ttagacggtt caccttattc tacattgcgt gaatttgcag ataacacaaa
    17041 aatccctgat gaaattggcc gctgggatcg tactattcca gaacgtttgg aaacacttgt
    17101 tgcaggctat cgttatctag cagatcttta ccaaaaagga atcgaagttt ctggagaaga
    17161 aggcgacgat ccaacacaag atatctttat cgaattcaaa acagccacag aaaaacgtat
    17221 ctggatgatc caagctcatt tgggcaaagc gccagagatc gacgcgtaaa aactgttgtt
    17281 gaacttgacc gaaaaagagg ttgtgaaatc agcgttttga cctgagtatt agagaaacaa
    17341 acgtcaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagctgat
    17401 tgaacaccgt ttaccaagag gttgtaagcc tgccgttcag ctccgagtca caagaaacaa
    17461 ttttaaaaaa cagcttctta tgttttatgg atattgtgac ttgtgaccga ggagttggca
    17521 ggagaacacc gtttattcaa aataaggggt tgtgacaaga cttttgtcac agcctctttt
    17581 tgtttttcat tttgacagga aacgaccctt ttatataaaa gaaagaaaag aagtaaagtt
    17641 tcatataaat ttttcaatca agcagaaaaa cgttgacatt gactagatta gcgggtaata
    17701 tgttaaatgg tattgtttgc cccacaaaga gccccggaaa ctcgaagtgt atgtcaaaca
    17761 tcagaactta aattggagga aaataacgtg cgtacaacat atatggccaa accaggcgaa
    17821 gtagaacgta aatggtatgt agtagacgca actgatgttc cattgggacg tctttcaaca
    17881 gttgttgcat ctgtactacg tggtaaaaat aaaccaactt tcacacctca tttggatact
    17941 ggcgatttcg tcatcgtcat caatgcagac aaagtgaaat taacaggtaa aaaagcgact
    18001 gacaaaattt attaccgtca cagcaactac ccaggaggat tgaaatcaat cactgctggc
    18061 gaattgcgtg ctaaaaattc tcgtcgtttg atcgaaactt ctgtaaaagg tatgcttcct
    18121 aaaaacactt taggccgcaa acaatttaca aaattgaacg tatacggtgg agcagaacat
    18181 ccacatgcag cacaacaacc agaagtttta gacatcacaa acttaatcta ataggaggga
    18241 atttcattgg cacaagttca atatatcggc acaggccgtc gtaaaaacgc agttgctcgc
    18301 gtacgtctag taccaggaac tggcaaaatt actgtaaata aaaaagatgt tgaagaatac
    18361 attccacatg ctgacttgcg tgaagtaatc aatcaacctt tcgctgttac tgaaacaaaa
    18421 ggcgcatatg acgtatttgt taacgtaaac ggcggaggat acgctggaca atcaggagct
    18481 atccgtcatg gtatcgctcg tgcattgcta gaagttgatc ctgacttccg tttagctctt
    18541 aaacgtgctg gcttacttac tcgtgacgca cgtatggtcg aacgtaaaaa accaggtctt
    18601 aagaaagcac gtaaagcttc acaattctca aaacgttaat atcctttata tatcaacgtt
    18661 tctggcactt ttcaattatt tggaaagtgc ttcttttgtt tttaagaaca catttaagaa
    18721 cacatatcaa tcacacttat tcaatcctct ctgaaaagct tcaaaaacag ccttatcaac
    18781 tatatctggt gtgttcacat atatctttgt tgtagaaata tctgagtgtg ttaaagcatt
    18841 tgaaatttga ttcatatctg ctccaccttg tctagctata gttgcataag tatgacggag
    18901 tttgtgtgga gataaatgaa ctaagtcagg atgccttctt ttaattgaat tgattcgata
    18961 gtttaggtaa tcggcatgaa caggacaatt tacttctcca gatggtttag tataagtaaa
    19021 gagatactga tctaacgttt gcttaatttt taatttcaac aattgatcag cttgtaccga
    19081 tttccattca cttagcaatg tcattacaac ttctggtact tgaatgacgg tatcttttcg
    19141 accttttgta aacttttttc tttgatattt atctaaagta tgtttaagac ggaccgtttg
    19201 tttttcaaaa tcaatatatt tccattgcaa agcgtaagtc tcactttttc tatcaccaag
    19261 atacagggta atcataaaaa gtgtgtaatc atgaaaagta agtaaatgat tattaaaatc
    19321 atcatttact gcttctatcc aattagtaag ttcttttgat gatagtgctt gcttaccttc
    19381 ttgtattctt ttttcttcta aagcattttt tttaggtgca gtgatacttt gaataatttt
    19441 agtagttcga ttaaattcga tataatttag tatttctgca atatcgaaca tggaacgaac
    19501 atatcctttt atgattttta tatttgcata ttctttcgat tttttggtta attcatctga
    19561 tatta
//
LOCUS       DADVXE010000051        19086 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.052, whole genome shotgun sequence.
ACCESSION   DADVXE010000051 DADVXE010000000
VERSION     DADVXE010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.052"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(387..1853)
                     /locus_tag="KB913_001977"
     CDS             complement(387..1853)
                     /locus_tag="KB913_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6820319.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="KB913_001978"
     CDS             complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="KB913_001978"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBB6820320.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            complement(4753..5112)
                     /locus_tag="KB913_001979"
     CDS             complement(4753..5112)
                     /locus_tag="KB913_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBB6820321.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(5142..5483)
                     /locus_tag="KB913_001980"
     CDS             complement(5142..5483)
                     /locus_tag="KB913_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820322.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(5480..6154)
                     /locus_tag="KB913_001981"
     CDS             complement(5480..6154)
                     /locus_tag="KB913_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6820323.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="KB913_001982"
     CDS             complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="KB913_001982"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBB6820324.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(8668..9858)
                     /locus_tag="KB913_001983"
     CDS             complement(8668..9858)
                     /locus_tag="KB913_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6820325.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(9879..10406)
                     /locus_tag="KB913_001984"
     CDS             complement(9879..10406)
                     /locus_tag="KB913_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBB6820326.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(10453..13242)
                     /locus_tag="KB913_001985"
     CDS             complement(10453..13242)
                     /locus_tag="KB913_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBB6820327.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(13389..13589)
                     /locus_tag="KB913_001986"
     CDS             complement(13389..13589)
                     /locus_tag="KB913_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6820328.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(14042..14362)
                     /locus_tag="KB913_001987"
     CDS             complement(14042..14362)
                     /locus_tag="KB913_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820329.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(14865..15983)
                     /locus_tag="KB913_001988"
     CDS             complement(14865..15983)
                     /locus_tag="KB913_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820330.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            16454..17761
                     /locus_tag="KB913_001989"
     CDS             16454..17761
                     /locus_tag="KB913_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBB6820331.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            17882..19081
                     /locus_tag="KB913_001990"
     CDS             17882..19081
                     /locus_tag="KB913_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBB6820332.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
BASE COUNT         5470 a         4026 c         3323 g         6267 t
ORIGIN      
        1 aataaatggt gttcaatcag ctgaccttca gcattagctc aaaaagcggc aaaatatgag
       61 gagctatttt tccgtttgtt tctctaatac tcaggtcaaa tcgctgattt tacaacctct
      121 tccttaaacg gtgttccaaa gcttgcatct gcggtaataa gcccagccaa acgaaaaata
      181 tgaggggcta tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac
      241 ctctgattca cggtgttcca gaagtagctt cttcgaaaaa caagccgaaa cttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttgt aacaagtatt tctattttaa ggctgaacca ctgtttctgg ttcagtgatt
      421 tctttgtttt tgtctcgacg agcaattgct ggcaagatca tacctaataa gatcaagacg
      481 attggtgtga tgatattcgt aaataattgg aaccaccatg ctttaggatc agcagtataa
      541 tctacttttg gcaccattcc taggatacat gcaaacgcag tgaaggcaaa gcaccaagca
      601 ccaaagataa aaccgatttt tggattttta acaaatttat attcagaatt gaatttctta
      661 taagctttat tcaacatcat atatgccaag aacacccata ggtaacgcat tggcatgaca
      721 actgagttca agttcgtcaa ccattttact aattcattca tatctttgat accaaaaatc
      781 ggcaacaaaa taatgattcc tactagtata cctgtcagaa gataaccatt caccaatgta
      841 cctttacgat tacgtttacg tagccagttt ggtacaaatt ctggatccgc atctgctaac
      901 aagattttta gtggtgcatc aattgaaaag gctaatgcgg agatttgtcc aatcatgttt
      961 gtcaatgcgt aaatgatcat caatgagtta ccgataccat agtaattacc taaaatttga
     1021 aaagcactgt atgccccatt tgccatcaag tctttaggaa tattatcact agcaaacagc
     1081 atacccattg cgactgagcc taatacagca caaatcccta ccattgctgc taagaagatc
     1141 atccctttag gaaattcctt tgcaggattt cttgtagagt tgacataagg ggatattttt
     1201 tccgcccctc caactgcaaa tactagcatc gaaacggttg tgaaataact gaaatcaaat
     1261 gttggaatat atgttttcac ttgattcata tgtggtgtgg caaattccat cgttggattg
     1321 atgaacggtg ccgttacagc taaaagaata aataagatcg acatgacgaa catcgctgtt
     1381 ccggccagtc cgccaatcac tttcaaagta gaaagtcctt ttgttgataa atataaaaag
     1441 gcaagaaata taataagtga aataactgct accatttgta ctgacatcgt atttacgata
     1501 tttccatttc cttggactgc ccaaccacca gcaatcagaa ttgcttgagg cttttgtgcc
     1561 aaataaggaa tatggacgac ccagtaagtc caagcggcat agtatgccag tcgtttatta
     1621 gatgtcgtat tttcgaccca tgaactgacg cctcctttac tatccttgaa ggctgatcct
     1681 aattgtccaa cgatcaatgc gtatggaata aaataaatgg ccaaaatcaa tagccaagag
     1741 gtgacaactg atactccttg ctgagcatag ttattaacta cattccccat gccccaaacc
     1801 atgttaaatg caattaacgc aacagtaaac cagcgtaatt gtttgttgtt cattcgttct
     1861 ctcctttatg ataaaaattt gttatccaga tgtaatcata ttcaattttt aacaaactta
     1921 caagacagtg ttattttatg tgtgtattct tttatttaat acacatcgtt ttttcatatt
     1981 ttttccatca aaaaaataag ttattttctt ttatttcatt gaccttattg aatttcaagc
     2041 tattttgaat tttctgcaaa attaaaaaca ttagttattt tataatccta tctattttct
     2101 ttacattttt cattaagaaa aggatataaa aaaaagagga cgttcattcg tcctcttttt
     2161 ttacatgcaa gcttcgcatg gcattcaaaa cagctaatac tgtcacccca acatctgcaa
     2221 atactgcatc tcccattgat gcaaaaccaa aagcacctaa ggcaagtacc aaaattttta
     2281 tcccaatagc aaagacaatg ttttgtttga cgattttcaa tgttttcttt gctaaatgga
     2341 ttgcttctgc aatcttcgat ggttgatcat tcatgatgac tacatctgct gcttcaattg
     2401 cagcatcgct tcccaatcca cccattgcga ttcctacatc tgctcttgct agcaccggtg
     2461 catcgttgat tccatctccg acaaatgcgg tctttttatt gtttctttgt aagatttcct
     2521 ctaaccgctg cactttatct tcaggaagca attcgctata tatcttgtcc acgcctactt
     2581 gcttcccgat atgatcagca atttttttcg agtcgcccgt caacatgact gtgttcttca
     2641 caccagcctg ttttaattga accaatgcgt ctacggcatc ttctttcaag gtatctgcaa
     2701 taacaagata accactgtaa ctttgatcga tcgctagata aagcaatgta ccgatttctt
     2761 gacttaaagg aaaagagatt tcaaatcttt ccatcaattt gtgattacct gctaatactt
     2821 gtttgccatc aacttcagct aagatccctt cacctgcaaa ttcctggata ttagttgttg
     2881 gtaaaagcgg acctgcgtag ccttctaaaa cagattgagc aatcggatgt gtagaaaact
     2941 gttctgcact cgcaatatat tgcatgaatt tctttggatc gatttttgta tcgatcgtct
     3001 ggatcgaaaa gtcacctttc gttaatgtgc cggttttatc gaataccact gtctcggttt
     3061 gcgcaagcaa ctccaagtaa tttgaacctt ttactaatac accgatttta cttgcgcctc
     3121 cgataccgcc aaagaaacta agtggcacgg aaatcactaa tgcacatgga catgagatca
     3181 ctaaaaatgt caatgctcga tagatccatt cagaaaacgc cgctccagaa acaacaagtg
     3241 gaggtaaaac agctaataaa acggccaatc ctacaacgac tggtgtgtaa tagcgcgcga
     3301 atttagtaat gaaattttca gctggtgctt ttttactgct ggcattttct actaattcta
     3361 ataatttgct gatagtagaa ttttcataag atttttctac ttgaactaaa aatggtttat
     3421 ttttattgat aaatccgctt aatactgttt caccaacata tacagattta gggactgatt
     3481 ctcctgtaag tgctgacgta tcgactaatg attctccttc gatgatcgtt ccatctaacg
     3541 gtacacgttc accaggcttc acaagtacaa actgaccgat ctgcacgtct tcagggttca
     3601 cggtcatcaa tccttccgtc gtctgcacgt gagctgtttc tggacggatc gccatcaatt
     3661 cgcgaatcga ttttcttgaa tgactgactg ccaatccttg gaaatactcg ccgatttgat
     3721 aaaatagcat cactgctacg gcttctggat attcaccgat caacatagcg ccaatcgtag
     3781 caacagacat aagaaaattc tcatcaaaga tttttccttt gacgatattc atcactgcct
     3841 tcttcactac atcatatcct atcagcagat aaatcaataa ataccctatc aagcgaattg
     3901 gttcattaaa atcaaataat agcaataaag cgatacctgc aagggaaaat aaaatccgga
     3961 acagcgtatt tctctctttt tcatttccat gttcagatac tttttcctta tctatttctg
     4021 ttactttgac atctggttct aattccttca ctactttttt tgtttcttgt tcaatcgtag
     4081 ccaaatgatc ttcctctgcg tcaatcgtta gttttccaga agtgaagttt accgttgctt
     4141 ccttgactcc attgatcttc tgaactcctt tttcgatttt cattgcacag ttcgcacaat
     4201 ctaaaccttc taatctgtaa cttttcattt taatgacctc ctcgcctcaa catatgaaca
     4261 tctcttcata actaattata aatgaatggt tattcatatg tcaaggtatc cgaaagaaaa
     4321 aatgaaaaac atctgcatcg gaaaatttct tccatacaga tgttttggct tattctttct
     4381 ttttctcttc gatcattgcc cctgctctta tccaacccgc acttgccttc ttgatcttga
     4441 caggatagca actaagtttg aagcctgttg ctggcaattt gtctaaattc attaattttt
     4501 cgataggaca atatcttttt tcaatccctg caaaatgtcc ttcccagata ttcgaagctc
     4561 cactacgctt tcaaaaatat agaaagagtt ctttaatgaa aattatttca actttccata
     4621 aacagtaatc ccatataaat aaaagacgta aaagtcacat gggagaactt atacaggaaa
     4681 acacatagag tcaggtgaaa tacatgtatc ccacctgact ctatgcgttt tctaaccttt
     4741 attattctct ttttatacaa tttctgcacc gaatggcatc aacgccaatc gagcaagttt
     4801 gaaagattgc ttggcaaaag gtatccctat gatcgtgata catagaagga tgccgctgac
     4861 gacatgtgcg agagcaattg gtaggcctga aacgatcagc cagatgatat taacgatcaa
     4921 tgacatgcca gactggtgat aaattacttc tttgccaaaa ggcgcaaaag aaagggaggc
     4981 gatcttaaaa cattgcatac cgattgggat acctatgatc gtgatacacc aaagtatccc
     5041 cgctgctaac cagctaagac caccgattag tccgccgaat ataaaccaga tgacatttcc
     5101 taaacaactc attgtatttc tccttctatt actgtttttg attaaaactg ggcaaaaatt
     5161 gattttattc ttcttttttt agcttccagc atcaagtatt ctgcaaattt tttttggatt
     5221 tcttccgtat tttcttttgt tactaatgtg tgttggatta gttttcctga tggtcgctga
     5281 tccacccgtt cttctgactg ttgcacgtcc gcttgcgcaa atccgataat ccgtttttct
     5341 tttgttacag caacgagcaa tagtttattc ttatcattta ggtcagctgc cgtttttgct
     5401 tttacgaatg attctggatg atcagtaatc agctgattga tttgaggtaa atcttctttt
     5461 actgcccacc gtatttccat catttctcac ttttctttcg ctcattttta tctccactaa
     5521 aaaaatcgac tgcggcaatt gcatctatcc agctttgtgc aatgatctca tgtccgccaa
     5581 tcgttgggtg gaccccatct tctcttgtat atttcgaaaa accataagca atccctaaag
     5641 cattgaatat gccatctaaa ggaaccagca atgcgccata ttccttagca agtttacgaa
     5701 caatttggat tttagggtct aagtctttac gccagccatg acggtcgtcg gttataggaa
     5761 gtacaaacgg ctccatcaag atgatgttgc agatttccgc tgtttgaagt tcatttagta
     5821 attttcgata aacggattca aattgctgcg cagatttctc agttccgaat atagcctgat
     5881 cgctagtatt atgccaggta tcattgattc cgatcaaaat cgatacatag tcaggttgta
     5941 aagctaaaca atcttcttgc cagcgtactt gcagatctgc aattttgtct cctcctatcc
     6001 cacggttcat gcattcaaat ttcatcgttg gatattggga gattagtttt ccggcaatca
     6061 aaagtggata acctttacct agatcagttg cttctgctcg gtctcttcct gcgtctgtaa
     6121 tgctgtcacc gataaataat atacgttttt tcatttgtca aaaactcctt tttgaataaa
     6181 acgatgattt tcttccttat attatcccat aagccctatc aagacgaaag agaaaatata
     6241 tgtataaaaa atgacaccag cctagtccct tcaatcaatt gaatgaacgc tcatcaagtg
     6301 tctagttttt tatacttttt ttcttaacgt gccggattcc ccttgattcc ttcgttgttt
     6361 ggtccagaga aatcgatcac acctaagctt ccgtcaatca gaccactgat gacgccatca
     6421 gaacatatat ttataggctc atctaagact tccagtaaat gttcttttac taatatctct
     6481 tctagattgc ttgggataga ttggtcataa ctttatctgg tccgatgatt tcaaggatga
     6541 attaaactta catatggatc attgcatgct gaaaatacgg acctactcca tcttcgaatg
     6601 ttactattag tttgttttca ggtactagat gctgctttat ttcaacagca gaagcatcat
     6661 caaatcagat ttccatttga ataaccttct ttgtatatgt ttgattgatt gcgatttcgt
     6721 tatagaacct tgtgaatcaa atagcaattt cttttgcttt cttctcttgt ctgctggaaa
     6781 cttcctttat cccgtatttt aaaaaaagaa ctgcgagagt tcgcagttct tttttttaaa
     6841 taaacgttgc tctccggcca actcctcggt cacaagtcac aatagtcatc aaacatgaaa
     6901 aactgttttt tgaaattact ccttgtgact cggagctgaa cggcaggcgc acaacctctt
     6961 gatataaacg gtgttcaatc agctgaccct cgatattagc taaaaaaacg gtaaaatatg
     7021 agaagctatt tttccgtttt gtttctctaa tactcaggtc aaggcactga tttcacaacc
     7081 tcttccttaa acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgcaaaaa
     7141 tgtggaaagc catttccaca aaatttttct taatactcga aactaaacag ctttttcaca
     7201 acctctccac taaacggtat tcaaaagctt acatctgcgg taataagtcc cgccaattca
     7261 aaaacatgaa cagctgtttt tgcttggctg ttctaattac ttgatgcaga acagcttttt
     7321 catcacctct tatggataaa ttcggttcaa caaacgtggg aatggaatag cttcacgtac
     7381 atggtcgata ccagcaatcc aagtgactgt tcgttcaagg cctagaccaa aaccagagtg
     7441 cggaacagaa ccgtatttac gtagatcaag ataccatgaa tattcttttt catccaaacc
     7501 gtgattacgg atttgttcta gcaagaaatc atagtctgtt gcccgttcgc ttccgccaat
     7561 aatttcaccg taaccttctg gtgcgatcat atctgcacaa attaccacgt cttctcttgt
     7621 tggatgtggt ttcatgtaga atggcttgat ggcttttgga tagtttagga taaagacagg
     7681 ctgttcgaat gaattcgcaa tgaacgtttc atgaggtgaa ccaaagtctt cgccccattc
     7741 gatgtcatca aatccatttt tcttcagtaa ttcgattgca tcatcgtaag taatacgagg
     7801 gaatggcaat tttgtataag tttttaagac ttctttgtct cgtcctagta catctaatgc
     7861 atattcgcaa tgatctaaaa cattttgtac taagaatgct acatattgtt cctgtacttc
     7921 taaactttct tcttgatgag tgaaagccat ttctggttcg atcatccaga attcgatcaa
     7981 atgacgtcgt gtttttgatt tttcagcacg gaaagtcgga ccgaatgaaa agacttttcc
     8041 gaaagccata gcagcagctt ccatgtataa ttggccactt tgagataaat aagctttttg
     8101 atcaaagtaa tttgtttcga atagatccgt agtgccttct ggtgcagaac cagtcaagat
     8161 cggcggatcg attttgacaa aatgatgttg attaaagaat tcatacgttg cacgaatgat
     8221 ttcatttctg atctgcataa tcgcatgttg tcttgaagaa cgcagccata aatgacgatg
     8281 atccatcaag aaatctgttc cgtgttcttt tggtgtgatc ggataatcgt ggctctcgct
     8341 taccacttcc acatttgtaa ttccgatttc ataaccaaat tttgaacgac tgtcttcacg
     8401 gatttctcca gttactaaca cggatgtttc ttggtgtaga tttttagctg tttggaaaac
     8461 ttcttccgac acttcgcttt ttacaactac accttggaaa aaggctgttc cgtctcttaa
     8521 ttgtaaaaat gcgatttttc cgcttgatcg cttatttgcg acccaagcgc cgattgttac
     8581 tgtttctccc acatggtttt tcgaatcgat gatttgaatt tgttccacgt atgactctcc
     8641 ttttatattc cttgaatttc ttcaggatta attttgactt ttactctcaa taaattgctt
     8701 gattctgcgt accgcttctt ctaacgtagc gcgatcagtg gcataactca tgcggacatt
     8761 ttctggtgcc ccaaagcctt cgccagtcac aagcgctacc cctgtttctt ctaaaagatc
     8821 ttctacccat tgtgtgacat tttcatactt acacatgcgt agcgtttctt ttacattagg
     8881 aaaaagatag aaagctcctt gcggcttttc aagagaaaca cccggcagtt ctgccacaag
     8941 cggatataac gtattcaggc gttcttcaaa ggcgttccgc atttcttcta ctgtatcttg
     9001 ctcacctttc aatgcttcaa cagctgcata ttgactgact gctgtcggat tgctagttga
     9061 ttgggaagca acagcgatca ttccattgat gatcacagga tttcccaccg cataaccaat
     9121 gcgccagcct gtcatcgcat atgttttaga cacgccgttg atgatgatgg tctgattttt
     9181 gattgcttct gaaatcgttg caattggagt aaactcattg ccattataaa ctaaacggcc
     9241 ataaatatca tcagcaacta tcaaaatatc attttttact gcccattcac cgattgcctg
     9301 cagttcattc ttgctataaa tcattccagt cggattcgat ggagaattga tgattacggc
     9361 ttttgttttt tctgaacgtg cttgttctag ctgttcaaca gtaactttcc agctattgga
     9421 ttcttcccct ttcacaaaga caggaagtcc ttctgccagt tttacttgct caccgtaact
     9481 gacccagtaa ggcacaggaa tgatgacttc atcttgcggg tcaaggatcg tttggaaaag
     9541 ggtatacaaa gcaaatttcg ctccgtctgt tacgactgtt tgtgaaggtt catagacaag
     9601 tccatagttt ttcttcagat aatcaacgat tgcctgtcga agctctggga ttcctgctgt
     9661 tggtgtataa tagctagctt tcccattgcg gattgcttcg attgctgctt cttggatgtt
     9721 ttctggtgtc gcaaaatccg gttctcccac agtcaaactc agcacatctc tgccttttgc
     9781 ttttaatgcc ttggcctttg ccgcagctgc caaagtgaca gacggttcta atcgttttgt
     9841 tctttttgat aactccatcc cattcattcc tttacctttt aaattccctt gattgtcttg
     9901 acttcatctc cagattcaaa gccaatcagg taataattca gtttcccatt tgtttctttt
     9961 cctactactt cccacacagg ctgatcatca tacatcccta aagcagcttt ttcgatttgg
    10021 atttcaggat gggccgcagc aattgtctgt tttgcttcgt tttcagtcag tccctttgtt
    10081 tgatccaata cttttacttt ttcaccagat ttaggaatga taacggcgat ttcttttcct
    10141 ttatcatttg tacctgtcag tgaaaagtat gtcttctttc gagtaaacca ataaaaatga
    10201 tcggtttcct caagatttgc atatttcttt gcgatttcta ctgcttcttt cttcgcctgc
    10261 accgccggac gactggaacg caagtaaaaa atcgagctga tcacgatgac cgctaataaa
    10321 aatacgatca agccaagtaa cacgcgatta atcgtttttt cctttgtctg ttttttcttc
    10381 aagggtcgtc gctcctttat cttcattcct tttcattata gcagatttta attatgaaaa
    10441 aagacagctc ctctaacttc cttcttcatt tttctttaag aattcatgga tatcctgata
    10501 gatttcctcc atagctagct ctttgatcgg tacttttttc ggtaatgcat ggatgatccg
    10561 tgcgccatat tttgcagtga ctagtcttcg atccaaaata agcaatacgc cacgatctgt
    10621 ctccgtcctt atcaagcgac ctaatgcttg gcgtaacttc aaagctgctt taggtacgga
    10681 ttcctggtaa aaaggattga tcccctctga ttctaaataa gcgttcctag ctttgaccat
    10741 cgggcgaagc ggattatcga agggtaaacg tgtgactaca acgatctgca aagcatctcc
    10801 aggcaaatct acaccttccc aaaagctgtc agcgccaaac aatacgcttt tttctgacaa
    10861 aatgaagcgt ttcaaaagct tctcccggct tccaccaaac ccttgagcta gtatttctcg
    10921 tcctttttct agcatagaca gatgcatttt ctgatagacc ttctgcaaaa catcatgaga
    10981 agtgaataac acaagtattg gccgatcttc ttgttcgatc agacctgtaa gtgctgtctc
    11041 taaataatcg atatatgctt gattgctgac ttgatggacg gcaggtgcct cttttggcac
    11101 atagatcctt gcctgtttct cataatcata aggagaggca atcactttaa gaggtgctgc
    11161 ttcaatgcca agcctcttag agagatagtg tcgattaggg ccgatcttca gcgttcctcc
    11221 aatataaaga atacgatcat atcgaggata ccaaacagtc gacggcaaca tagccgcttg
    11281 aaaatcatgg agatgaaaaa tcatctgctg cgctgtgttc ccaggaacga accaatggat
    11341 caaatgatct cgccagtctt ccagccattg atccatcagc aagtattgct tgtctaattg
    11401 atcaaatagg ctatataaac ttgctaaatc gatccgcatc tggtttgtcc agctttcttg
    11461 gataatctca aaagtcagac gcatttgtga ctgtagctgc tggatctcct gataaaaaag
    11521 ctgcaggtga tcaatggctg tcccagattc cagtggcagc tgatccaaca tctcttttgt
    11581 catcatgact tcttctggat actgtccgtt aggttgcttg ccgctcacta aactcattaa
    11641 tccttctgcc atacaaatct gtgcttcgca tagcgcagaa agttcttctc gataaatcga
    11701 taaccagcgt aaggcttcat gttctttcgg taaatagctt tgtattcggt caaacagctg
    11761 atttggttct tctaattgct ggatttgttt atggaaatag ttaatactta atcgtttgtc
    11821 atttactttt tcagcgattt ccggcaaatg atgtacttca tcgatcaaca aaaatggact
    11881 agctggaagc aatggttctt ttcgctgtgt ttcttgtact aaaaacgcat gattgacaat
    11941 caaaaaatta ctttgcctga ttttcttttg caagaaacga acaaagtctt gttcgtaaaa
    12001 tgactgattt cttgctaaaa atccaatacc tctgtgcgcg atatctgcaa agaatgaatg
    12061 gttcaaattt gttaaatgta attcatccaa atcaccagtc ttcgtttgcg tcagccaaac
    12121 taagaccgcc atttgataca aagcatattg tttttgttct ggcggttcca caagtgtgcc
    12181 tttaaaacgc tgcaaatcaa tatagtggcg atagcttttg ataattacag gttgtatggg
    12241 ctgatctagc aattgattca gcaatggaat gtctttttct atgatctgct gctgcaaaac
    12301 tagcgaaacg gtactgatga cagcgggttt ttcaggtgta gccaaataac tcaatggcag
    12361 cagataaccg attgttttac ccattcctgt agctgcttcg atcatcaaat cttttgattc
    12421 atcttttgtg aaatggtcgt agaccgcatt catcagtctg ttctgttctt ttcgatacat
    12481 cagtgtttta ccaaacattt tttcttttgc ttgttttttt cttggatatg tccgctcgcc
    12541 ataatggacg gatgtgaata gttccacttc ttttttctgc aaagctagcc catcgacgat
    12601 ttctaatgag ggatcaagtg gctctggttt ttctttcatt tcttcaatca catgataaat
    12661 gaaacgactc gtatccatac ctgtgtgtct acttaatcgc gcaatctgct ctaacgtgat
    12721 gattggcaat tttctcatcc gttcttcgat cagcaaaaga agttgacctg tcacttcggc
    12781 atcactatct gcctgatgag gattctcatg aataaatcca aggctttctg acaaatcagc
    12841 taagcgaaag cttggttccg tcggcaagaa aatttgtgca agttctactg tatcgatgcc
    12901 tggtatcttc aaactaggaa gtccgcatcg catgagttca tggttcaaaa aattataatc
    12961 aaaataaata ttatgcgcga caaatatggt gtctgccaaa agattgtaaa tcgtttgggc
    13021 gacatcttcg aaataaggcg ctttttggac gcgttgattc gtgatccctg ttaaatgctg
    13081 gatttgtttt gaaatcttcc gccctggatg aatatcgatc gaaaaacgtg aagtgatccg
    13141 acctgattca atcatgacgc agccaaattg gatgatccga tcttcttttg gattcgtccc
    13201 agtcgtttcg atatcaacga ctgcataagt tcttggtttc aaaatatctt cctcttctcc
    13261 tgcctctaat gttcttttga aattatacta caaagtgcag aaaaatactc tcatcgcttt
    13321 ttaaagaaaa tagacaaaaa cgcccagaca cgcaaatgtc tgggcgttta ttttttagta
    13381 taggttaatt aagctttagt aacgtttgtt gcttgaggtc cgcgttggcc ttcttcaaca
    13441 tcgaaagtta ctgcttggcc ttcttctaaa gttttgaatc cgtcgccttg gatagctgag
    13501 aaatgaacga atacatcgtt tccgttttct gcagtgatga atccaaatcc tttttctgag
    13561 ttaaaccatt ttactgtacc tgtttccata ataaaaatcc tccttgtgta tcaacacata
    13621 ttttgcaatt acttgaatgg tgtatatctg gaagatgttt atttgaaaca agctaccaca
    13681 gattaccgaa caaaaactac tcctatagta tatcataccg tttacaaaaa agctagagtt
    13741 tttcgacttt ttttattaaa aaaagttttc tcagcgatta cataaagtga aaaaccgaac
    13801 ttttttttaa aataaacgac atattgttca gttggtgttt ttttgctctg atgttctttt
    13861 ttaaactaaa aaaattattc tttctgacta cttatcggtt ctgtttcaac ggtcgaggct
    13921 ggggaagatt ctttagtagg tctgatgttc tcatggtatt tctgatagcc tatgacagtt
    13981 accagaagaa caaggcaaac caatacgacc aacgagatta gtttttcttt tttgctcata
    14041 tctatacctc ataaataaca ggatgatgtc catcatattt ctgagtatga gtaaaagcaa
    14101 aagctgcagc tgtagaatgt aagaaatgcc agcaactttc ataatcacag gtcggacagt
    14161 accaaaagta accaaatctt ggctgcaaag accgttcttc tgtttcagga atcgcagaat
    14221 caagatctgg tgtctgtaca taaacatttt tgtacagacg tgtgcctgta ataggaaacc
    14281 gctgtgtttc ttcagcaaaa actggctgac ttgttaaact tagggataga gacagcaaac
    14341 accataacag tctttttttc ataaagacct ccttatcgat aagtttttcc caattaaaat
    14401 catatctcaa gaacgcccgt tattcacatt ttgttcataa atgatgtttt ttgtatcata
    14461 atcgtcaaaa agaggtcgtg accacgtcac aacctctttt ttaaacggtg ttccagaagt
    14521 agcttcttcg gaaataagcc gaaatttcac aaaaatttga gaaataattt ttgtcaatct
    14581 cttcttattt cttgaagctg accacttctg tcacaacctc ttccttaaac ggtgttcaaa
    14641 agcttgcatc tgcggtaata agcccaccaa acaaaaaata tgaagagcta tttttgcttg
    14701 ctgttcttat tacttgatgc agaacagctt tttcacaacc tctcatacac ggtgtttaat
    14761 cagctgacct tcggtattag ctcaaaaaac ggcaaaatat gtgaaactat ttttccgttt
    14821 gtttctctaa tactcaggtc aaaacactga tttcacaacc tcttttaata acgaagaatc
    14881 gctgtcagac tcttttcatc tggcgcatct ttttgatcca aaataaacac ttttccgcca
    14941 ttaatgatca catcatctgc taatgcattc aacacttgac gccgatcata ttctgtttca
    15001 ggatcttcac cgaaaccatc agctaagttt gacgtagcga taaataaatg tgacactttt
    15061 ccttctttcg cagctggaac gatatcaact aactgatcga tgaatttctt atctaagagt
    15121 ttattgtatt cttttgattc ttgagctgcg agttcacttg acagcttctt cgccccttct
    15181 tcgatatctc taaaggatag ctgcgcagga gaagcagaaa tcgcaacgtc tgcacaataa
    15241 tagggatttt tagcaatttt tttgaacatc gtctgatttt ctggtagagc aaataaataa
    15301 atcggccatt gttctggatt ttcgaaagaa tccttcaagt acgtatcaac tgcttggtaa
    15361 tagttgaccc aatcgatctc tacttcttca tcttttggat ttacgccatg gaaagttact
    15421 ccatctcggg ctccgcctcc tccattagaa gagaagttca aaccgccacc tgtcagttca
    15481 gatcccaatg cagtaacgac atcaaccggt gccccttctg gtagagatac ttcttttact
    15541 tgtttgttgc tgacttcata caatttcatg gagtcgcggt tcaatcccaa taaataataa
    15601 gaatagttga actgcccatt tttgataata gccagtaaat aaggaagatc acttacatag
    15661 tattgatcgt ctaccgggat actcaaacga tggatatagg tttggtcagc agttataatg
    15721 accgctacac tcgtagttgc actacgccaa aacgaaggat ctcctaacaa attttcaatt
    15781 ttttcttgga acggggacca gtcatgttcg gaatattttt tctcaaaacg tttctttgct
    15841 tctttcgcaa aatttttgaa tttgatctga tctttttcca catcttgatg ggcgacatgc
    15901 gtattcagca tgatcgtgac gaatggtcct ttagcgcctt ctgaagtcaa ttgtgacaat
    15961 aattctttat ccttttttgc cataaacgta cccctcctaa aaaaatcatt cctttgtttc
    16021 tatctaaagt ctaccacaac actatttttc catacaataa aacgtatcta aaaaaataaa
    16081 acggtttcta cggttttaaa tttagctatt tttttaagtt atcttcataa tttcctcaat
    16141 tatttagccc cagtcttcaa ctattcttca tgaaatgctg ataaactaag aaaaagaata
    16201 aaagaggtgg atcttatgca tttgattatg attttcagtt tattaagtat tatcagttta
    16261 tttgctttca gcgcttcccg cttattagat gcggaaacac agcctattcc tgtaaaagta
    16321 cgtaaaaacg accgctaacc ttccataacg tgcgttctta tcctaaagtt ttttcagaaa
    16381 cattgaaact ctctcccctc tctgataaaa ttttaatttg tagcgaaaca aattaattac
    16441 aaggagatcg gatatgtcca taaaaaaaac acgtctagtc ctattattgg ctagtctcat
    16501 tctttgcctt gcttcttttc taccagctgt tgctgtgcaa gctgaagata ctttcaaagt
    16561 aaatgcaaaa gcagcctttg ctgtagatgc gcaaagcggt aagattcttt atgatcaaga
    16621 tggagaaaaa accatgggga tcgcttcaat cacaaaaatc atcggtcttt acatcgtcct
    16681 tgatcaagta aaagaaggga aactatcatg ggatgataaa gtttcaattt cagattatgc
    16741 agaaaatttg agtgtcaccc cagatttatc aaatgttcct ttgcataaag aaaacaccta
    16801 caccgttaaa gaattattcg actctgcaat catccagtca gccaacgctt caatggttgc
    16861 cttggcagaa aaaatctctg gcagcgaagc aaaattcact gaacgaatga aagaacaatt
    16921 gaaagattgg ggtatcaaag atgcaacgat cgttaatgca tcaggactga ataactctta
    16981 tcttggcgaa aaccgaccag aaggtactgg agaaaacgac gaaaatcaaa tgtctgctca
    17041 agatgtggct atcgttgccc gtcatttgat cttggatttt ccagaaatac tggatgtatc
    17101 tagcactacg acacaaatgt ttggcgaaaa cacgcaatca ccagtagaaa tggtcaactg
    17161 gaactggatg ctcccaggat tcgtgaatta taaagaaggc gtggacggat taaaaactgg
    17221 tacgactgaa cttgcaggag cctgtttcgt cggtacgatc actaaaaacg atcaacgaat
    17281 catcactgtc gtattgaatg cagacggcca tgcggaaaac ccaagtgccc gtttcaatga
    17341 aacagctcgc ttaatggatt attgctacga caattggtca gaaaaagagc ttggaaaagc
    17401 caatgcaagt atccctagtc taaaaaccat tgatgtaaaa gacggaaaag aatcaacagt
    17461 gcccgttgtg cttaaaagtc ctgtaaaagt atgggtacgg aacgatatgg atactggaaa
    17521 attaacaatc acaccaactc ttgacaaaaa acaagtcact gacaatgaga tccaagcacc
    17581 tatggataaa ggaacaaaaa tcggtaccgc aacgatcacc ttggcagaag ataaattagg
    17641 ttatcttgaa gacaacaacg cgccatccac agaaatcatc acggataaaa ccgtagaaaa
    17701 agcaaatatt ttcgttattg gctggcgacg cgtcgcagaa tttttcggta acttgtttta
    17761 attgaacaaa aagaaaaaag catctttcca tgtggaagat gtttttttgc tttttctagt
    17821 ttaaataaca gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt
    17881 tatgaatcta accagagatc tgattttttt ggttctctat cttattgggg tattctccat
    17941 cgtttattgg cgaaaacaga aaaaggatcc ttccttgttc ttttacagca gtacatggac
    18001 gtttgcggta atcttgactt attttgtcgt gttggaaatt ttttattcga ccttttattt
    18061 tttgattccc ttagtgtttt tcagtatctt tgccttttcc tatttttcag aaaagcgaag
    18121 gctgttgaat ggtcttttat tcaatatttt cctcattagt tttggtatct acttgtttgt
    18181 cttgctatac gaaacacaaa atatttttct tggcggactg attgccttga tcacgatccc
    18241 gttactgctt gtctttctat tcggcattta tggattgatc gtttttcttt tttggaacgg
    18301 tgtcacagtt ttacgtagag agtcgcattc attagctaat cttttaacgt tgatactagc
    18361 catttttctt acattgtttc ttgtttttga ctttttcttg ttaaaatatt taccacaatg
    18421 gataaatgct ttgtttttct gcatcccatt gatcttgatc tatctattta tcgtattcta
    18481 caactttttg actgtctcat tcttgtatca gttcaaccgc cctcgataca accaagactt
    18541 catcgttgtg ttaggcgccg ggttgatcaa tggagaaaca gtttctcctc ttcttgccaa
    18601 gcgaatcaat aaggcgattg ctttttattg ggcacaaagc cgtgcgacat taaatccgcc
    18661 tatcctatta atgtcgggtg gacagggagc agacgaaaaa gtaccagaag caatggcgat
    18721 gaaacaatat gccatggaac aaggaattcc tgaaagagat attcttgtcg aaaccaattc
    18781 gacaaccact ttggagaata tgcgctattc aaaggaaatc atggatcagc aaatgaaagg
    18841 tccctatcgc gcgatcttca gttccaacaa ttaccacatt ttcagagctg gtctctatgc
    18901 acgacaagcg aaactgaagg caaatggcat tggggcaaaa acagctttct attacttgcc
    18961 taacgcgttt ttaagagaat acatcgccat cttgatgatg aacaaaaaaa gacatatgat
    19021 catttgcgga ttgcttttcg caggttccgc attcttatca ctgatcactt tacttttcta
    19081 aaaaaa
//
LOCUS       DADVXE010000052        18049 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.053, whole genome shotgun sequence.
ACCESSION   DADVXE010000052 DADVXE010000000
VERSION     DADVXE010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.053"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(57..1793)
                     /locus_tag="KB913_001991"
     CDS             complement(57..1793)
                     /locus_tag="KB913_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBB6820333.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(1790..2494)
                     /locus_tag="KB913_001992"
     CDS             complement(1790..2494)
                     /locus_tag="KB913_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6820334.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            2625..3128
                     /locus_tag="KB913_001993"
     CDS             2625..3128
                     /locus_tag="KB913_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBB6820335.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            3088..3426
                     /locus_tag="KB913_001994"
     CDS             3088..3426
                     /locus_tag="KB913_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBB6820336.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            3447..4865
                     /gene="ffh"
                     /locus_tag="KB913_001995"
     CDS             3447..4865
                     /gene="ffh"
                     /locus_tag="KB913_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBB6820337.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            4977..5555
                     /locus_tag="KB913_001996"
     CDS             4977..5555
                     /locus_tag="KB913_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBB6820338.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            5559..6080
                     /locus_tag="KB913_001997"
     CDS             5559..6080
                     /locus_tag="KB913_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6820339.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(6159..6713)
                     /locus_tag="KB913_001998"
     CDS             complement(6159..6713)
                     /locus_tag="KB913_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBB6820340.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            6966..7241
                     /gene="rpsP"
                     /locus_tag="KB913_001999"
     CDS             6966..7241
                     /gene="rpsP"
                     /locus_tag="KB913_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBB6820341.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            7253..7504
                     /locus_tag="KB913_002000"
     CDS             7253..7504
                     /locus_tag="KB913_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBB6820342.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            7629..8420
                     /locus_tag="KB913_002001"
     CDS             7629..8420
                     /locus_tag="KB913_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820343.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            8590..9111
                     /gene="rimM"
                     /locus_tag="KB913_002002"
     CDS             8590..9111
                     /gene="rimM"
                     /locus_tag="KB913_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBB6820344.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            9101..9862
                     /gene="trmD"
                     /locus_tag="KB913_002003"
     CDS             9101..9862
                     /gene="trmD"
                     /locus_tag="KB913_002003"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBB6820345.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            9998..10345
                     /gene="rplS"
                     /locus_tag="KB913_002004"
     CDS             9998..10345
                     /gene="rplS"
                     /locus_tag="KB913_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBB6820346.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            10718..11380
                     /locus_tag="KB913_002005"
     CDS             10718..11380
                     /locus_tag="KB913_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820347.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            11459..14686
                     /gene="fss3"
                     /locus_tag="KB913_002006"
     CDS             11459..14686
                     /gene="fss3"
                     /locus_tag="KB913_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBB6820348.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            14800..15114
                     /locus_tag="KB913_002007"
     CDS             14800..15114
                     /locus_tag="KB913_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6820349.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            15127..15501
                     /locus_tag="KB913_002008"
     CDS             15127..15501
                     /locus_tag="KB913_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6820350.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            15511..15855
                     /locus_tag="KB913_002009"
     CDS             15511..15855
                     /locus_tag="KB913_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBB6820351.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            15926..17278
                     /locus_tag="KB913_002010"
     CDS             15926..17278
                     /locus_tag="KB913_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBB6820352.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            17338..>18049
                     /locus_tag="KB913_002011"
     CDS             17338..>18049
                     /locus_tag="KB913_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBB6820353.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGML"
BASE COUNT         6029 a         3231 c         3842 g         4947 t
ORIGIN      
        1 tctttcgaag caggatgagt catccaactt taaaacgcac gagcagttgc tcttttttac
       61 attttcggaa tggtaacggt gaaagtcgaa cctgttccaa gatgactgtc tacagtaatc
      121 gtaccattaa ggagttgcac gtagtctttt acaatcgcta accctaatcc ggtcccgcct
      181 gaatgtcggc ttcgcgcctt gtctacgcgg taaaaacgct caaagatccg ttcctgatcc
      241 tcaatgtcga tacctatacc aaagtcttgg acagaaaacg atagatcatc tgttgcctga
      301 tagcggataa taatctcgct gtcgcttttt gaatattgga cagcattttc aattagattt
      361 ttgataattg gataaaggat atctgtttta gtagtaaatg gttcgttctt tccaatcaat
      421 cgaatcgtca accgtttctt ttcgatgatt ggctgataat tttgaacgat ttgctggaaa
      481 taaggttctg tataaattgt ctggatctcg taagaattct cgccatcttt tgacagctgg
      541 atgatttccc gaatcagttt atctaaccgg atcgcatctt tttgcatgat ctcaagaaaa
      601 gaagtcagag tttgcgggtc atcttttgca ccatccagta aagtctcggt aaaaccaatc
      661 agtgaagtca caggagtttt taattcgtga gagacgttgc caacgaaatc cttttgtagc
      721 ttttctaaac gtcgcacttt cgttaagtca tacgccaccc ctagaatctg tccggtacct
      781 tctgaattag taaagtagcg caaactcaag tctaatgtct gccgaccttc tgtaagggtg
      841 atctcctgat ggatcagcgg atgctcagga gtcacttgat gaatcagctg aatgagtttt
      901 ggctcttgaa tgacttctgt gtaccgctgt tcaggttgat agcttaccac gtttaaatgt
      961 agctgcatct ttggattaag cagtagtaaa cgagaatcag catcatcaat caggaatacg
     1021 ccaatcatca gttcgttcag taacgtatat aattgctctt ctgtggtagt acacgcccga
     1081 tacatcttac tcatttgttc gctcaacgca ttaatcgtct gatacaattc ttcccattga
     1141 tcgggtgttt gcatgattac ttccgcctga ttaggatttt gcaccatttt ttttagtacg
     1201 ggcagcacgg ttttcaatgg ctggtttttt tgatagatca gataatagat cattcctgca
     1261 agaacaagga agaaagacag aaagaagaaa aagacccaac ggcgaaaact ctcagttctc
     1321 ggtaaaaaac cgcttgtcgg ttctgcgata cgtaaaatgg cttctaactg gccacttttt
     1381 ttgactggta atgcgacata taaaagatcc tcattcaaag tagtactttt gcgcaaagcg
     1441 ctacctaggt tcccaccatt caatacggct ttgatttcgg gacgggagtt tcgctgttca
     1501 ttcaatgttt cattgtttgt gtcaaataag atctttccag tagcatccat taaagtaatc
     1561 cgttcgttcg actgatggac gaattcttcc aaagcagttt tgttttgcgc tgcttggagg
     1621 ttttcgacat ctaattgccg gatcagcagt tgtgcttttt ttgtcaggta gctttcttgc
     1681 tgttccacga tctgctgttg aaaataatgg gaaatcaatt gccagccacc aaaaaacaaa
     1741 ctaactaaaa gaataagaaa gaagagacgt tcataaattt ttttccattt catcgtttgg
     1801 gttcctgaaa cttatagcca aatcctctaa tagtcaccaa gtactttggg tgttttggat
     1861 ctcgctcgat tttttctcgc aaatgactaa cgtgtacatc tacgattcgg ctttgtcctg
     1921 cgaagtcaaa attccaaatg cggtctagca atgtgtctcg gtcgatcaca cggtcttttc
     1981 gtttcatgaa ataaacaagt aattcaaatt ctttcggtgt tagttcaatc agatggtcgt
     2041 ctacggtcac ttgataattg gtcaaatcag cagtgatttg tccaatcgat agatattcag
     2101 gctcagcttc atcttttgat tgcttacgag gttcaattcg tctgaatatt gctttcatac
     2161 gggctaatac ttcgcgagga ctaaatggtt tggtcaaata gtcgtcagca cctatttcta
     2221 ggccaatgat ccgatccact tggtcatctt tagccgtcag catcaaaatc ggtgtttcat
     2281 ttttttcttg acgcagccgc tgagtgatct ccatgccatc catcgttgga agcatcacat
     2341 ctaaaatgat gaaatcaaat gattgttcta atgctaattc taatccttcg cctccatctg
     2401 tggcactggt taccttgtag ccttcttttt ccaaattgaa cgtcaagagc gttacaatag
     2461 aaggttcatc atcaacaact agtatttttt tcattcaaat ctcctttaaa taggtttcat
     2521 tctgtttata ttttagcata gaatcagtac aaagggctat tttacaaaag aaataaatgg
     2581 tataatagga aggcactttg ctgaatagaa aggaagagca gtcaatgatt ggaatcagtg
     2641 catgtttagg cggtctggcc tgtcgctatg atggacagaa aaaagaagta ccagaattga
     2701 tggaactagt tgaaactgga gaagctgtca tggtctgtcc agaagtgatc ggcggattac
     2761 caattcctag agatcccgct gaaatcattg gtggaaatgg attcgatgtg tggaaagatc
     2821 aagcaaaagt atggacgaca agcggcgaag atgtaacgga agcgtacaaa aatggcgcga
     2881 tcaaagccta tcaaaaattg caggaaaaac acattgatct agtcatcatg aaggaaaaaa
     2941 gcccttcatg cggaacccat tcgatttatg acggaagttt ttccggaata aaaaaaaatg
     3001 gtgccggagt ggctactgct tattttattc agcaaaaaat gactgtgctc tctgatgaag
     3061 aatggctgaa aactagaggt gagcagaatg gaaatcgaaa agaccaatcg aatgaacgcg
     3121 ctctttgaat tttattcgac cttattgaca gaaaaacaaa tgaactacat ggaattatat
     3181 tatgcagatg atttttcatt aggtgagatc gcggaagaat acgaagtaag ccgacaagca
     3241 gtatatgaca atatcaagcg gacaagcaag atcttggagg attatgaaaa aaaactccat
     3301 cttttttcta attatattgt tcgagaacag gtattggaaa atatgactgc atatattaca
     3361 gataagtacc cggaagataa aaaactactt gaatatgtac agcaaattca agcaatcgaa
     3421 gaataaataa aaggaatgaa gaaaatatgg catttgaaag cttaactgaa cgtctccagc
     3481 aggcgatggg aaaaataaga aaaaaaggaa aagtatcaga agctgacgta aaagaaatga
     3541 tgcgggaaat ccgccttgcc ttactagaag ccgatgttaa cttgcaagta gtcaaagatt
     3601 ttactaagcg cgtacgcgaa cgtgcggtag gggcagaagt gctggaaagt ttatcacctg
     3661 cacaacaaat cgtaaaaatc gttgatgaag aattgacgat cacacttggt tctgaaacag
     3721 cagagttaaa taaatcacca aaaataccaa ctgttatcat gatggctggt cttcaagggg
     3781 caggtaaaac gacctttact ggtaaattag ccaattattt aaagaaaaat gaaaatgctc
     3841 gtccgctcct aatcgcaggg gacgtatatc gaccagctgc gatcgaccaa ttgaaagtat
     3901 taggtcaaca gctagacgtt cctgtatttg atatgggaac tgaagtcagc ccggtagaga
     3961 tcgtccgtca agggatggag ttagcaaaag aaaagaaaaa cgactatgta ttgatcgata
     4021 cggcaggacg tctgcatatc gatgaaacat tgatggatga gttgaaacaa atcaaagaat
     4081 tgacgcaacc aaatgagatt ttgcttgttg tcgatgccat gactggtcaa gatgccgtca
     4141 acgtagctga tagcttcaac cagcaattag gtattacagg ggtcgtcatc actaaacttg
     4201 atggggatac tcgaggcggg gcagcactat cgatccgctc agtgacaggc gcaccaatca
     4261 aattcatcgg ttctggtgaa aaattgactg acttagaagt attccaccca gatcgtatgg
     4321 ctagccgtat ccttggtatg ggggatatgc tgacattgat tgaaaaagcg cagcaagact
     4381 acgacgagaa aaaagcggaa gaacttgcac agaaaatgcg ggaaaattca ttcgatttca
     4441 atgactttat tgaacagctt gatcaagtga tgggtatggg cccactggaa gatctaatca
     4501 aaatgatccc aggaatgaat caagtccctg gaatcgaaaa cgtcaaggta gatccaaaag
     4561 atgttgaacg caaaaaagcg atggtttatt ctatgacgcc agcagaaaga gcaaatcctg
     4621 atctgttgaa cccaagccgt cgtcgccgaa ttgctgccgg ttctggaaac agtgttgttg
     4681 aagtgaatcg aatgatcaaa caattcaagg aatcaagaaa aatgatgcag caaatgtcca
     4741 aaggggatat gaacatccca ggtatggacc aaatgtttgg ttcaggcgtc aaaggaaaac
     4801 taggcaaaat ggcgatgaat cgaatgatca agaaaaataa gaagaaaaag aaaaaacgga
     4861 aataagatga aaaaaacagc ttcggtacag actgaaaatg tctactgccg gagcttttct
     4921 atcagcaatt tttattcttt actaatacaa ttactctaaa cgaagaggtg gcacagatga
     4981 gatgtccgtg gagtgaacaa acagaaagta tgcggcaata tcatgatact gtctggggtg
     5041 ttcctgaata tgatgaccaa aagctgttcc gaaaattgat gcttgatatt aatcaagccg
     5101 gattgagctg gcagacgatt ttaaataaaa gtgaagcatt cgatgaagca tatgatcgat
     5161 tcgatatcaa aaaagtcgca aattatggag aaacaaaaat cagtgaacta atggaaaaca
     5221 aaggaattat tcgtaaccga agaaaaatcg aagcagccgt ccaaaacgcc aaagcagtct
     5281 tgaaaattca agaagaaatc ggcagttttt cagagtatct ttggtcgttt tctaatggaa
     5341 aaatcgttga ttcttcttat cattcacaag aagaagtccc aacaacaagt cctctttcag
     5401 atgaattagc aaaagatcta aagaaaagag gatttaaatt tatcggaagc acaacaatct
     5461 atgctttttt agaagctgtc gggatcatca atgatcacct tgacagttgt ttccgcaaag
     5521 aagaggtcgt acgtatcggc agaaagggcg aataaagcat gcgaaaaatc atattttatg
     5581 gtgctataag tttagatggc tatttggcaa cgaaaacgga tgatcttcaa tggctttttg
     5641 acactccaac aggtaagcaa actacttatg aagcttttta tgaaacaatc gatacgacca
     5701 tcatgggcag aaaaacttat caggaagcaa aaaaatattt ggagaccgaa gcaatttatc
     5761 cagagaaaaa gaatttcgtt ttttccaccc acgcacaatt acaattgcca gatgctgagg
     5821 tcgtaaacga agatcctgtt gcttttctaa aaaatctaca aatgacagaa ggaaaagata
     5881 tctgggttgt gggtggcggt cgattgatca aaccgctatt ggaacatcaa atgattgatg
     5941 aatggtatat ccagattacc cctgtattat taggggacgg gattccttta ttccaaaaag
     6001 gaacatatga agcgcgtttt gaaatgctag acacgacacg attcggtgaa tttatcgaat
     6061 tgcattatgt acgaaagtag aagtaaataa aataaaaaag gcaactatat gcagaaatgt
     6121 cctgtacata gttgcctttt ttattaccgt tatgcttttt actctgttaa tttgttagaa
     6181 aaatctagat acgcatctaa aatcgtttgg aagaaactta atgttccttc aacgatatta
     6241 ccattttcat caattagatt cgcaacgttt ccgatatatg cttccggttg ctgcaaggtt
     6301 ggcacattca aaaagacaag tgattggcgt agatggtggt ttgcgccaaa gccgccgatc
     6361 ccacctggtg atgcagtaac gactaaacct ggtttatgat cccaaacact gtgtccataa
     6421 ggtcttgagc ctacatctaa agcatttttc aatactgctg gcacagaacg gttgtattca
     6481 ggagtaacga aaacgacacc gtctagtccc ctcacttcct cacgaaaacg agtccattca
     6541 gcaggagcct gttctggagt ttcgagatcc tcattgtaaa atggcagatc atcgattttt
     6601 acaaatacac tttcgtaccc ttcaggaagc aatttcgcaa aagcttctgc tacttttttg
     6661 ttgtaagaat cttttcttaa actaccaata aaaaatccaa ttttttttgt catacgattt
     6721 ttcctccttc aaactatcta taataatctt acaaaagata agtaactgga gcaaataaaa
     6781 acacttactg acaaaagcta catagaagat agattactta tttttaacaa aaaagaagtc
     6841 taaaatcttc tattttctaa aaaaaatcga atttaatcaa gctgtaaaga aaaaaagctt
     6901 tacagggtaa aaaaaaactg ttacactaca tcttgtgaat aaaacaatgg aggtggaaat
     6961 aaataatggc agttaaaatc cgtttaaaac gtatgggttc taaaaagagt ccgttttacc
     7021 gtatcgtcgt agctgattca cgttctcctc gtgatggacg tttcatcgaa actgtaggta
     7081 cttacaatcc tttgaaagac cctgcagaag tagttttaaa agaagactta gttcttgact
     7141 ggttatcaaa aggtgcacaa ccttctgaca ctgtacgtaa catcctttca aaagaaggcg
     7201 ttatgcaaaa acaccacgaa gctaaattct caaagaaata aggtgaccgg atatgaaaga
     7261 tttaagcgac ttagtcttaa caatcgttcg tccgctagtc acttatcctg atcaagtcaa
     7321 gttagacgtc gtagagtcga aagactttta cgagtacaat ctaacagtgg ctcctgaaga
     7381 tattggccgt atcattggaa aacaagggcg tgttgctaaa gcaatccgca caatcgttta
     7441 cggtgttcgg atcaatgcac cgaaaaaagt gcgtttgaat atcatcgatg ataaggaaaa
     7501 gtaaataaac gtgctgtact cgaattttcg agtgcagctt ttttgttttt tttattaatt
     7561 gaagaaatga ttatttggca aaacaagcaa gaaagcgtat ccttatagga ggagggagtg
     7621 aacagccaat gagaaagaaa atgttattta ttccatttgc tctattgtta agcgcttgta
     7681 gttcggttac tcaagaatca gacaatacac atctatcaag cagtatatct gaaactgtta
     7741 ccagtccaga aaaaagtagt accaaaacgg cttccaccac tgaacaaaca atggctacct
     7801 caaataatga gaaaaagact gctttagacc agttgaaaga acaacagcca aatgttccca
     7861 tgcctctaga tgtaccagtc tcttcaggct atctcaatat cgcagcgaca catacaaagc
     7921 aaggttattc tattttatat tacagaacag atcgtcccct cgggttgaat gctgacgaat
     7981 tgaatcaaga aacgcctatt gcaacctatc tatatcaata tgggtttgct tctagtcaag
     8041 aaacaatcca agttttgcag ccatttgaga tcgacacaaa tggtcagcaa gtggacttag
     8101 gttctcgaat cacagggtat cagcaaggtg cagcaggttc aagttttctt gaatggcaag
     8161 aaggaaactg gcgtattcga atccgtggga ataatataga aggccaagat cccttactat
     8221 tagctaaaga aatcgtagct tatttggaag aaaacagtct accagcacct gaacaatttg
     8281 gtaaaattac tgttgatatg ggtgatacga cgaatcgagc cgtagaagta agctggcaag
     8341 aaccgaaaaa tgcctatacg atcactcatc aagatcctat gtctgcgttg aagatggcag
     8401 tttctatgaa gaggttgtga aatcagcgcg ctgatctgag cccatcattt aactccaagt
     8461 cacaggaagt aatcaaaaat agcacgccgc atttttgcat aattttggct taatacctta
     8521 aaagaaaact agaattgcct cttcacacat gctaaaataa aacagacaaa aaagaaatgg
     8581 ggatataagt tgactgaata cttgaatgta ggaaaaatcg taaacacaca aggtatcaaa
     8641 ggcgaagtcc gtgttatctc aacaacggat ttcccagaag aacgttacaa aaaaggaacg
     8701 gtgctaacac tattccaaga cggaaaagca cctgtggaat taacagtcaa aagtcatcgc
     8761 aaacataaaa attttgactt attgagtttt gaaggacatc cttctatcaa tgatgtggaa
     8821 aaatatcggg atggcatatt aaaagtgtca aaagacaact ctgtagatct agctgaaaat
     8881 gaattctatt accatgagat catcggtctg catgtattag aagatggaac tgagttaggt
     8941 aaagtaaaag aaatcttgtc accaggtgcc aatgatgttt gggtcgttca acgtccgaaa
     9001 aaagctgata tattgcttcc atatatcgct tctgtcgtca aagaagtcga tttagaagct
     9061 ggagtggtcc gtgtagaaat tccagaagga ctgattgacg atgaagattg atgtattgac
     9121 tttatttcca agaatgtttg aaggtcctat gggggaatcc atcatcggta aggctgtaga
     9181 taaaggatta ttagatatca atatctctaa cttccgcgat tattcagata acaaacatca
     9241 gacagtagat gattatccat acggcggtgg agcaggtatg ctgctcaaag tccagcccat
     9301 ctatgataac atccaagcca ttgaaaaagc tgcaccggat gtcaaaaaaa gagtaattct
     9361 tcttgaccca gctggtaaac gattcgatca gaaaatggca gaagaatttt cacaagaaga
     9421 acacttagta ttcatttgtg gtcattatga gggatatgat gaacgtatcc gcacattagt
     9481 gacagatgaa gtttccttag gagattatgt ccttactggg ggagaattag gtgcgatggt
     9541 catgatcgat gcaacagttc ggcttttgcc agatgtgtta gggaatcaga cttcagctca
     9601 aacggattct tattcaaccg gtttattgga acatccccaa tatactcgcc cggcagaata
     9661 taaagggatg aaagtaccag aagtattgac aaatggaaat cataaattga ttgaagaatg
     9721 gcaattaaaa gaatcactaa gaaggaccta tcaacgtcgg cctgatcttt tggaaacact
     9781 tgaatggaca cctcaaatga cgaaattttt agaagaaatc aagaaagaag aacaagaaaa
     9841 aacagcagat gaagccaagt gactttttct aaaatcttct ttacagtagg ttgataatat
     9901 gttagtattt tatggtgagt gcaaaagcac ttaactatta cgatattccg ctgtgagaaa
     9961 agctcataag aatatttgga ataaggagaa gaaaaccatg aatccattaa tcgaagaatt
    10021 aacaaaagaa caattacgtt ctgacatccc agcgttccgc cctggtgaca ctgtgcgtgt
    10081 tcacgcaaaa gttgttgaag gtactcgtga acgtatccag ttatttgaag gtgttgttat
    10141 caaacgccgc ggtgctggaa tcagcgaaac ttatacagta cgtaaagttt ctaacggagt
    10201 gggcgttgaa cgtacattcc cattgcatac accacgtgtt gcaaaaatcg aagtagttcg
    10261 ctacggtaaa gtacgtcgtg caaaattgta ctacctacgt gcattacacg gaaaagctgc
    10321 tcgtatcaaa gaaatcagaa gataaacacg gaaaacttcc ttggaaatct gaaatttgtg
    10381 aaaagtcctt gtatatcaag ggctttttct tttttctcta tcacagtttt aagccatttt
    10441 tggctgtttt ggaccatttt tcaatcatat tcccttaaaa attgtcctag attgtccgac
    10501 attgactatc agtgtcgtca aaatagggca aaatttagta gtcagcttga cgacaaatat
    10561 aatacgaaaa ataccaaaac atttaccgaa tttagcaact tttgaaccca agtttctcaa
    10621 agggtcagct attagcaaaa aagacaaaac atgtactttt ctactaaaaa gttgatgtga
    10681 taggcttcta tctaaataac tattaggagt ttttatcgtg aagcaaaatg atggacgtat
    10741 catttggaaa aatcaaagtg agttaaaact gattttaaca attaatgaat tcatcgaaaa
    10801 acacggaatt acatctagcc gtcaatacca gaaaaagcta tcagaaaatc caaattctgc
    10861 accaagtatg tggttcatta acaaaaaata tggatcatgg gagaatttat tgattagtat
    10921 aggacgagaa aatactgggt atggaaaatg ggctagaatg tcagaacaag aattattgga
    10981 aatagtagaa gcctttatta agtgcgagaa gataacctct caacgaatgt acgaacaaaa
    11041 atcagtaggg aagaatattc cttcacttag taccattaaa aagatgttag gagatatacg
    11101 tccacttttt aaagaaaaaa atgatggatc tcgatttact gatttcgaac tgctgttaga
    11161 actaaaaaat gaaataatcc gattaaaact acaggatgat ttatcaatga caaagtttcg
    11221 aaaactagtt caatccccaa aactaccatc agttgataca attatgaaaa gaacgaacaa
    11281 aaattgggag gaattgatgg cagagattgg atttgattat cgaagaatca aaatttataa
    11341 gcagagaaac aacctatcca agacaaagaa aactaaatag tatcactcta aatcagacgt
    11401 tcaaaattaa aatttggacg tcttttttat tacccaaaaa cgaaaggaga tttattttat
    11461 gaaaaagcca agatttaaga attggcgttt gctcgcaaca ctgagtctat tatgccaaac
    11521 aattggtgga tcgcttggcc caacgattgc ctttgctgat gaaattactc atccacaaac
    11581 ggtaactgtg gaattggatt tggctcacca gtatgctgtc gaaggtacat ttagcgatgg
    11641 tcgtcccatg tcagaagtta ccgttccgca ctatgcagtt tacaatggtg tgaagcaaga
    11701 tattttctgt attgagccag gggtgccgat ttacaatgag ttcactcctg gttatgagaa
    11761 aaatccattg cctgatatgt cggagaaagc gaaattagtt tccgttttat ggaaggaagc
    11821 tggtacggat gtggatacac atattgtggc ccagaagatg atttggcaag aagttaatgg
    11881 ctacacgctt cactcaatta aacgttctga tggtagtgca gtaaatatcg cagccattga
    11941 gtcaaaaatc aatcaagcca ttgcggatta tcaaaagaaa ccaagcttcc ataactccac
    12001 agtgaaaacc gtgttaggtc aatcgactac tgtgacagat acgaacggct tgaatttatc
    12061 ggagtttgat gaagttgtcg agaatatcgc aaatattgat tatcgtgtga acggcaatca
    12121 actagtgatt actccaaatg ccaattcaaa agagagtggt gaattaaccc taaagaagtc
    12181 agctaataca ggaacaccgg tagcttataa aatggctggt caacaaactt tgatggcggg
    12241 ggcaattgat aagcccaata cctacacaat caaaattgat gtggaaactg agggttcttt
    12301 gaagattaaa aaagtcgata aagaaacagg aaatgttgta ccgggaaccg ttttccattt
    12361 agactttgga aaaacattac ctgcaaaaga cgtgaccacc gataaagaag gcattgcgac
    12421 attggatgag attcctcatg gcgcgaaagt aaccattact gaaaaatcag tgccagctcc
    12481 ttatacgatt gacactacac caatcaccgc aaccattaaa tctggtgaga ctatttctgt
    12541 gacttcaaaa aatactcgcg aaaaaggtca aatcattttg aataaaatgg gggtggaaac
    12601 aggaactgat ctttggaacg acaaatactc attagccgga aatacgtttg ccattcgcaa
    12661 agacagtcca accggtgaaa ttgtccaaga aatgaccacg gatgaaaaag gtcatgcgga
    12721 aacaccaaaa gagattgcca atgcgttgga attgggaacc tattatgtga ccgaaaccaa
    12781 agctagtaat ggctttgtga atacctttaa accagtaaaa gtcgaattga actatgtcaa
    12841 tcaaaccgtg gctcttgtta ccagtaacgt aaaagggcaa aaccaagaaa tcactggtga
    12901 aaccactttg acaaaagaag acaaagatac cggtaatgaa actcaaggta aagctgagtt
    12961 taaaggagct gaatatactc tctttactgc aaaagatggt caagcggtca aatggagtga
    13021 ggcttttaaa ccagagttag tgaagggaac gaaagcttct gatgaaacgg tgactttgac
    13081 tttagatgaa aagaatcaag ttgctgttaa acacttagcg attaatgagt attactggca
    13141 agaaaccaaa gcacctgaag gatatacctt ggatgaaaca aagtaccctg tttccatcaa
    13201 aaaggtggat gataacgaaa aaaatgccgt gattacccga gatgttacgg caaaagaaca
    13261 agtcattcgc tttggctttg atttctttaa atttgctgga tcagctgctg ggactgccga
    13321 aactggcttc aatgatctga cctttaaagt atcgccattg gaaggaacca gtgagattac
    13381 aggtgccgaa gatgaagcaa ttacagctta taacgagcaa ctaggttttg atggctatgg
    13441 caagtttgaa aatcttcctt atggggatta tttacttgaa gaagtagagg ctccagaagg
    13501 atttcaaaaa attacgccat tagaaatccg ttctactttt aaagaaaata aagcggatta
    13561 cactaagagt gaatacattt ttacgattac cgaaaaagga caaaaacaac caattaaaac
    13621 ggtgaccgtt ccttacgaga aactgacgaa taaagcattt tctgttagct tgaatcgttt
    13681 gatgctctat gatttacctg aagaagaaga tagcttaact tctcttggga cttggaaaga
    13741 cggaggcaaa gaattgacag accttgattc taccgagcta gttgataaat tgagctataa
    13801 cttgcatgaa atcaaagaag actggtatgt ggtagcgcaa gccattgatg tggaagcgac
    13861 aaaagctgcc caagaaaaag atgaaaaagc caaaccagtg gtaattgccg aaacaaccgc
    13921 aacgttggcg aataaagaga aaacaggaac ttggaaaatt ttgcataaat taaccgcaga
    13981 acaagttttg gataaaacca tcgtcttatt caactatgtg tatgaaaaca agaaacccta
    14041 tgaagcaggt gatgatccag tagcgaaaga tgctagcttg aacaatcaag cccaaactgt
    14101 caattgtacg gtggaacgcc atgtttccat ccaaacaaaa gcccacctag aagatggttc
    14161 gcaaaccttt actcatgggg atgtggtgga tatgttcgat gatgtgtcga ttacccatga
    14221 tgtactggat ggctcaaaag aagcttttga aacaattctg tatgcattac ttccggataa
    14281 tacgaccaaa gaaatttgga aatctggcaa aattgattat gaagtgaatg acaaagaatt
    14341 cactaaaacc gtacttgcgg aaaaagtgga cacaagtaaa tatccagaag gtacaagttt
    14401 taccttcaaa gaaattaact atggcaaaga cggaaacatc aatgggaaac acaatgagga
    14461 tctaaaagaa aaaactcaaa ctttaacacc taaaaaagtt ccgacaacac caagtgcacc
    14521 agaacaaccg gaaataccaa ctgttccaag tgactctcaa gaatctagtc ctacagtaaa
    14581 gacattccca caaacagggg agaaaaattc taatgttctg ctgtttattg ggtttacctt
    14641 gatctttgcg actgctgggt attatttctg gaatcgccga aactaaggtg atgtgatgaa
    14701 acaactaaat aggaaaaacc aacgtgcgcg accgcctcct aaaaaaagtg gtcgcgctat
    14761 ttttgtatcc aaaactaaaa atgaaaagag gaaaagaaga tggaattgaa atttgttgtg
    14821 ccagatatgg ccgaaacctt tggaaagata aggtatgccg gcgaaggcga agttttaact
    14881 gaaggatatg ggcggaatac tacagtaatt ggtcgtagtt atcatttgta ttccagtaag
    14941 caacgagccg atgatattga agtggtggta gctgcggaag ccggcgaaaa ggattttgat
    15001 caagatcaac cactaaaagc cgtgaatccc catttggttg ccaaaggcta tgagattgag
    15061 aatcgtgggt ttaccgacta cgtgttgtat gtcgatgatt tagtgaaagc ataggaggaa
    15121 aagaagatga gattaacaga aggtattgtt gtagattcag gactaacgtt tgggaaatta
    15181 cgattttccg cattacgccg agaagtacgg aagcaaaatg aggatggaac ggttagtaac
    15241 gaggtaaaag aacggactta taatttgaaa tcctctgcgc aaggtcgaat gatccaagtt
    15301 agtatcccag caaatgtacc cttacgcgag tttgcctatg acgcagaggt agagttggtc
    15361 aatccaatca tggatacggt cgccaattat gttttccgag aaggaactac tgtcaattgg
    15421 ttcattaagg ccgatgattt agtcttgaaa cgacaaccag atcagggaaa ttctacaaac
    15481 caaaatgaag gaaagaaata ggtgaagcgt atggaaatta atgttgaaca tattttagat
    15541 tgtctcgatc aatatggaaa aggtgagcta acggaggaac aactcactaa agcattaacc
    15601 tatgatgaaa aaatgtttct gattatgcat caagggttac tggaagtagg taacgatgtc
    15661 gaagaagatt ttgatgtact gaattggtta ggggaagaag agtccttctt tatggttatc
    15721 gaagtaaatg aaagtctatg tcgagaagcc gaaaccgtat tggaagaaat tggtgtggaa
    15781 atgccggatg ccattgaagt ttttttaaag caactagtgg aaacgaaaca actccctata
    15841 gcagtaaatg actagcataa ctgcttgaaa ttggatcaat gaaatcctat gaagcttttt
    15901 tcgattggag gtggaaacca taaaaatgta caaagggcat cgtatacggg caggagatca
    15961 gcacttggtt tatcactttg ttcttggctg gctactcgct ctgttcatcg gttggatgag
    16021 cgtcttttat tttcaagagc ttagacaatt tgatatttct aagctatcac tttctactat
    16081 agaaatcgtt cgttctataa aagatttaat ctatttgcta ggaagtctcg ttctttcagg
    16141 aagcacgatg ttgctttata tacacttttt tcaggatcat tggcgcagtt tgtggcatcg
    16201 acaaaagcta gcccggatga ttctagaaaa tcattggtac gaagtaaaac aaactcagag
    16261 tgaaggattt ttcaaagacc tcaatagtag tcgaaccaaa gagacaatca gttacttccc
    16321 caaaatctat taccgtatga aggatggttt actttctatt cgcgttcaaa tttcactggg
    16381 aaaatatcaa gatcagcttt taaagctgga aaagaagtta gaaagtggtc tatattgtga
    16441 actagtagaa aaggaactca aagactccta tgtggagtac actttactgt atgatataat
    16501 tgccaatcga attgggatag acgaagtagt ggcagaaagt ggggctttgc gattgatgaa
    16561 aaatcaagta tgggcttatg attctttacc tcatatgtta atcgctggcg gcacaggtgg
    16621 tgggaagact tactttttac tcactatcat cgaggcttta ttaaaatctg atgccgagct
    16681 ttttgttctt gatcccaaaa atgcggactt agccgattta ggtacggtaa tgcctcatgt
    16741 ctattcccaa aaggaggaaa tttctgcttg tgtggaagat ttctatgagc gcatgatgac
    16801 tcgtagcaag gcaatgaaag aaatgcccaa ctacaaaaca ggagagaatt atgcgtttct
    16861 tggacttcca ccaaactttt taatctttga tgaatacgtg gtttatatgg aaatgttaac
    16921 gacgaaggaa agtgcggtga ttttgaataa gctcaaacaa atcgtgatgt taggtcgtca
    16981 atctggtttc tttctgattc tagcttgtca aagaccggat gcgaaatatt taggagacgg
    17041 gattcgcgat caatttaatt tccgggtggc tttgggtcgt atgagtgaac tgggatattc
    17101 catgatgttt ggcgaggttg ataaaaaatt ctttatgaag cgtatcaaag gtcgaggcta
    17161 tgtagatacg ggagggagtg tgattagtga gttttatacg ccacttgtac caaaaggata
    17221 tgatttctta agggaaatta gcgacattgg tggattaaac gttaatacgg aaggataaaa
    17281 taatagtatg tagcctagga gtgtcaagaa tcctgggctt tttttacgag gtgatttatg
    17341 acatttttag atttattcgc tgggattggt ggcttttgct taggtatgga acaagcgggt
    17401 caccagtgta tcggcttttg tgaaattgat gattttgctc gccagagtta taaggcaatc
    17461 catgatacaa gtaaggaggt ggaaatgcat gacatcacaa gtgtatcaga cgagtttatt
    17521 caatctctcg gaccagtgga tatcctttgc ggtggatttc cgtgccaagc tttttcaatt
    17581 gcgggaaagc ggcaaggatt ttccgatact cgaggtactt tattctttga aatcgctcgg
    17641 ttcgccgcta ttctccaacc taagttttta ttccttgaga acgtccgggg attactcaat
    17701 cacgaaggag gggctacgtt cgagacgatc ctccgaacgc tggatggatt ggggtatgat
    17761 gtggaatggc aagtgcttaa ctcaaaggcc tacgttcccc aaaaccgtga gcggatcttc
    17821 cttatcggac attctcgaga cgcatgtacc gaacaagtat ttcctatcat tggatcgtct
    17881 ccaacatctg atcaaaacat cagaaactta ttaaatatca acccttccaa tcgaggaatg
    17941 gggggacaag tctatgggtc agatgacgta gcgcctacct tgaccggtga tgaaggaatc
    18001 aaaatcgcat tgccggtaga tgatggaatt tctgtagcgg gtatgttac
//
LOCUS       DADVXE010000053        17098 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.054, whole genome shotgun sequence.
ACCESSION   DADVXE010000053 DADVXE010000000
VERSION     DADVXE010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17098
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.054"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(429..1043)
                     /locus_tag="KB913_002012"
     CDS             complement(429..1043)
                     /locus_tag="KB913_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6820354.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1649..2026)
                     /locus_tag="KB913_002013"
     CDS             complement(1649..2026)
                     /locus_tag="KB913_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820355.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2326..3207)
                     /gene="galU"
                     /locus_tag="KB913_002014"
     CDS             complement(2326..3207)
                     /gene="galU"
                     /locus_tag="KB913_002014"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBB6820356.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(3250..4269)
                     /locus_tag="KB913_002015"
     CDS             complement(3250..4269)
                     /locus_tag="KB913_002015"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBB6820357.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(4902..5906)
                     /locus_tag="KB913_002016"
     CDS             complement(4902..5906)
                     /locus_tag="KB913_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6820358.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(5919..6968)
                     /locus_tag="KB913_002017"
     CDS             complement(5919..6968)
                     /locus_tag="KB913_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6820359.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(6985..7806)
                     /locus_tag="KB913_002018"
     CDS             complement(6985..7806)
                     /locus_tag="KB913_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6820360.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(7793..8572)
                     /locus_tag="KB913_002019"
     CDS             complement(7793..8572)
                     /locus_tag="KB913_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6820361.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(8589..9059)
                     /locus_tag="KB913_002020"
     CDS             complement(8589..9059)
                     /locus_tag="KB913_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6820362.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(9071..9490)
                     /locus_tag="KB913_002021"
     CDS             complement(9071..9490)
                     /locus_tag="KB913_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBB6820363.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(9571..12348)
                     /locus_tag="KB913_002022"
     CDS             complement(9571..12348)
                     /locus_tag="KB913_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6820364.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            12539..12763
                     /locus_tag="KB913_002023"
     CDS             12539..12763
                     /locus_tag="KB913_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820365.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            13542..15257
                     /locus_tag="KB913_002024"
     CDS             13542..15257
                     /locus_tag="KB913_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820366.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            15260..17023
                     /locus_tag="KB913_002025"
     CDS             15260..17023
                     /locus_tag="KB913_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820367.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
BASE COUNT         5054 a         3501 c         2907 g         5636 t
ORIGIN      
        1 ttatttctat tagaaaaagg tatcctgttg gacaattttg ttatatcagg taaacttcat
       61 tgcaataatg ataacaaatg tactataatt actttgtaaa gagttttggg gaagactctt
      121 tcatcaacgt gtattaagag acaagaaaga atccatatgg attctttctt gtctcttttt
      181 ccactacttt ttatttttct gacactacat attcttataa ctcatttctc ataactgtga
      241 aacaacttat aaaaataaca aactttaaac aaaacaagct taaaatcaaa gatgatccat
      301 cttaaaataa ctaaaacaaa aaaagtagtc gttgttaatc ctcattaata atcgttttct
      361 ttttttcaaa cgctccattt ttatgtggaa cattattttt ttaaggaact ttgtcaacat
      421 gtggataact attttccact tgtgtcctgg actagctgtt ttgctgtaaa atacaaaact
      481 tgctgcagca aaaagatcgt tgcaagagag gctgttccgc agatcgctgg atctagattt
      541 ggcaaagtca agactgcatc atgtaaattg gcgtggttgt ccaaaaccaa atcagcaaat
      601 tcaaataatc gcaaaccact gctatgttgc gatttgatac ttcgtgacaa atcaaatcca
      661 gtaacaatga ttaatggatg accattttct ttgatccact gagctagttc gatgattgcc
      721 gggtttcttc cttcattcga aagaagaaga aaaatgtctt ctgatttgac agaaagctga
      781 tcaataattg cctgtcctgc accttctagc gtttcataga cacctccggc tggattttca
      841 atcaatatac ttggtacaag atccggggtt tgatcccaaa attcaaatgc tacaccactt
      901 agtgtgcggc tagcatatat ctgcaatcta ccaccttgat taatttgttt cgcgatccaa
      961 gtgccagctt gaagcatcag cggctcttct atccttaatt tctcttccaa ttggtgataa
     1021 tagtcaaaat aacataaact catttatctc tcccgcctag ctatacttga catgaataga
     1081 aacagctgcc taatctaagg aagtacataa aaaaacagta gttagacagt aacacatgtg
     1141 gtctttgctg tttcaaacac aaaaaaggca ttgaacgaat acgcccaata ccttgacata
     1201 gcaaataaaa caacgtgcag accatggaaa atatctacat aggggtagaa ttttcaccct
     1261 agattaggta caataaatta ggtcgatgca ctgcattgac tatggcaaaa tgatcggtca
     1321 gggtgtatgt gtgtgactgg tcattccctg attcttagcg ccaactaagg gtcagggagc
     1381 ctttttttat tcagctgttt ctatctgaat ttattgtaag taatctctta tccaagtgca
     1441 agcaagaaaa tacaaaaaaa cattggtatg atttatatat atataaataa cataaaaaaa
     1501 ggaatggctt atcccgatac aacaagcatt cctttaaaaa agattctttt atataagtga
     1561 aaaaagcttt tttccaccaa ttaaataaat ctctcatctc aatagtttat ccattatttt
     1621 atcttttttt gcgtatacct actaaatatt accgtcttct tctcgttctt ctactttgtt
     1681 cgagagaatc tgtactagaa aaagtagttg tatgtctacc ttttctgcct atccgagact
     1741 ttcttttcat atatgggata taaatgatta gatacagtac agcaaaaaat aaagcaaata
     1801 cgcaagcttc ccaactacct aacgccaatt caaccatcaa ggtagcaacc ccaacggatg
     1861 ctgcatacca gataaaaatc agaaacgttt ctttttttct gaccatgcga aacatgataa
     1921 atagactaat aagcaatagt ggcaacacaa atatccaatt gcttccttcc atcagccact
     1981 tgagtatatc aagcagcgac tgtgcaacag cgactaattt tcccatagtg aacacacacc
     2041 tttttttata attaaaaaat tcgccttttt attctactat gaatcttctg gcttggcttt
     2101 catttctctt atgtaatcat tttcttttat acaacttaaa aaaaaattaa accattagca
     2161 taatattttc tgaatctatt cacgaaagtc tttttctatc tttcgttttc cacgactcaa
     2221 ctgatctaga gtcaaaaaac taaaacgaca gttgcgcaaa tgacgcacaa gctgccgctt
     2281 taataacaaa tagcctttca ttctcagcag gccacttatt tccagttaac tttctgttct
     2341 tagcttttta ctcaactgga taatatatgc acttaatgaa gtcccaattt ccgaatgttg
     2401 aagtccatat tcaatatttg tcttcatata tcctaactta tcgcctacgt cgtatctttt
     2461 tcctttaaac tctctcgcat agaccgcctc tgtctggtta agagtctgaa gtgcatccgt
     2521 tagctgtatc tcgtttcctg ctcctggttc ttgagtttct aatatctcaa atattttagg
     2581 agtcagtaga taacgtccga taatggctaa attacttggt gcttttccca tttcaggttt
     2641 ttctacaaac ccttttactc tgcaacgacc cttttcgcta tctgttttag gatcaataat
     2701 tccgtattta gatgtttcat tttctggtac acgcatgacg gcaacagcgg aagcttgtgt
     2761 ttcttcataa tccatcatca attgttgagt caatgggata tcatctttca tcaaatcatc
     2821 ccccagcatg acgacaaacg gttcatttcc tataaatgct tttgcttgaa gcacggcatc
     2881 ccccagtcct cttggatgag attgacggat gaagtgaaga ttgacttgag tcgtttcttc
     2941 aactaaagcg agtaattctg ttttttcctt ttcccgcaaa ttgttttcca attcgatatt
     3001 tgcatcaaag tgatcttcaa tgggtctttt ttcttttccc gttacgatca agatgtcttc
     3061 gattcccgaa tccaatgctt cttccacaat aaactggatc gttggtttat ccacgattgg
     3121 aagcatttct tttgccatgg cttttgttgc cggcaaaaaa cgtgttccta gcccagcggc
     3181 aggaatgact gcttttttga ccttcacttg ctgttcctcc taaacgacga ttaactattg
     3241 atcatctatt taacgaagag aaaattcatt ctccattttt ccgtcacgta acatgatttc
     3301 ttttgctgct tttttgatat cttctccatt atacaaaaca ttatagattg tttgagtaat
     3361 tggcatctca acacctagct gttgagctag ctctactgct gcttttgtcg ttgccacacc
     3421 ctcaacgacc attcccatgt tttctagaac ttcttccagc ttatgtccct gtcctaacaa
     3481 gttaccggca cgccaattgc gagaatgaac acttgtacaa gtaacgatca agtcccccac
     3541 accactcaaa ccgataaatg tcagaggatt ggcacccatc gcgacaccaa gacggctgat
     3601 ttctgccaat cctcgagtca tgattgctgc ttttgcatca tctccgaatc ctaatccatg
     3661 gatagcgccg gcaccaattg caatgatatt tttcagtgct gcaccagttt ctacgccaat
     3721 cacatcatta tttgtataaa tcctgaaata atcattcatg aacagttttt gtacataggc
     3781 tgctgctttt tgatcaatac ttgcagctgt aattgttgtg atatcatgta ctgccacttc
     3841 ctcagcatgg ctaggaccag ataatacaac aattgcctgt cttttttctt ctggaatttc
     3901 ttcagccaaa acttctgaga ttcgtttatg cgtatcttgt tctagtcctt tacttgcatg
     3961 tataatgatt ggcttagtat tcattttacc aataagttcc tgtgcgactg aacgaatcgc
     4021 ttttgttgga acaacaaata aaatagcatc tgcgttatcc actgcttctg ccaattcttt
     4081 atatccgata atcgattctg ggatcgtcaa atcaggtaaa aaatgctgat ttgtatgata
     4141 cttattgatt tcatcaatct gttcaggtac atttccccaa atacggacat catgcccgtt
     4201 ttctgccaat gtttgtgcta aagcagtgcc ccaagatcca ggaccaagaa ctgcgatttt
     4261 ttgtttcatg gatattcctc caaataaata attgataatt tccattatag tatacatttc
     4321 ttaaagttgg gactaatttc cattgttttt aagtgtttgt ttacttcttt tatcgttttt
     4381 acttgaaata atcaatgata tgttacaata gtctacattt tatttttaca ctcgttatgc
     4441 tttgcttgtt cctaagagga agcagttttg acaatgttac taccagcatt actattagga
     4501 ggttaggaaa cttctcctag tgagtattga tttaaaatac ataagagaca gattgaacat
     4561 ttctaaatct gtcaggtcct gcaacggaca gattgtctct gttgacggtt gacataggaa
     4621 cttttgtttt agtcaacatt ctggatacaa aacgctatgt aaactggcgc aactcgttgt
     4681 acttggactt ttactacgga tccatgcaac aactaaatag tactattgca taacaaaaaa
     4741 tggttggcac ccacatgtcc cattaaacag attataagtt gaactgtaga taatgcaaaa
     4801 aatgtgtttt ataacgtaat tgatgccaat attttaaaaa aataaaggga gcagttatcg
     4861 ctgctctctt tattttttat attcttttta tccagtctat cctaataatc aaactgacga
     4921 tagtagcggc gtatctctaa tggatggcag ttcaactgct ccacatgagc atcgatgcgt
     4981 tgtgtcacta catgcatcaa taagaaagac aaaacacgtc cgcgatattt ttcactgata
     5041 ccttctactg gatagtcttt tgtgtctatc aatgtataat tgctgcaaat ttttggcaaa
     5101 agtttagcca cacgttcaga taacactctc tgttcatctt cgcctaaaaa taatgtgact
     5161 ggggttgttt cttctacgat ctctaacgtc ccgtgaagaa actcggcagc atggatagat
     5221 ttcgatggaa gccagctttg ttcttcccag taacacatgg catatgaata aacagctccc
     5281 cattgattcc ctgctccaat aaaataatgc atactatcac gtcgatgttt ttctgcaaat
     5341 gataagccaa atgcatctgc ttttttctct gcttccacta accctgttgg taaataacgt
     5401 tcgagctgtt catagtattc tgaataagct tcgaattctc cattcaaata catcaatcga
     5461 tctgctgcca taaaaaattt gatttgttct gttccaggag ctggataagt gaccacaaaa
     5521 tcgcatagct gagacaactt actgttcgct ttatcgataa atccaatcag tgtcgctcct
     5581 actttcttga tttgttctac tgctttcact acttcttgag ttgtaccggt aacagaggac
     5641 aaaataacga tagaatcttt tgttaatctt ttgtttccag tagtgtaata ttctgcagca
     5701 tgctgtacaa agacaggcaa gttgcttttc ccattcatat aagtgacagc ttgcatcgag
     5761 gaagcatacg ttccaccgat tcctagataa tagacagcgt caaatttttc cgcataaagt
     5821 ttatcgatga tttcttctac ttgcggacgt aaagctagtg cgccttttat tgctttgatt
     5881 tgttcttctt cattgaattt cagcatgatt tccacctctt ataatttact tttcaagact
     5941 gtatcaaagt cttcaaaaat ctttttgttc aagtcaatac ctttagctac tgcggtttta
     6001 taagcgaata gttgaaacgg aacgacaagc gctaatacag acagatattc atcacattct
     6061 attgctaatc caagtgtttt ctcgtttctt gctttttttg tggtaatggt gagagtctct
     6121 ccaacgtacc gactcatata tctttgcaac ttttgcgaac gttccttatt tacactttcc
     6181 ccttcaataa agaatagcaa atgcgaagca tctgcctcca ggtatgggcc gtgcatataa
     6241 gcttctaact caaatccttg tgacggaacg cggattgttt cagtcaattt cgtctctgct
     6301 tctttagctg ttccccagtt tggaccatat ccaatggtga cgaaacgctg tgctaaacga
     6361 aataaacttt gatatccatc aaaaaattct tccgtttttt gaataatcgc tggtaaatgg
     6421 ttgattattt tgcgcaactg ttgcatgtag tcttgttcta tttttttgct gattttattt
     6481 ttacttattc caattcctat ccctaagagt agtaactgta aaacagtcgc agaatagcct
     6541 tttgtaacga agcctactga ttctaccccg gcacctaaat caataatttg tgcagcttct
     6601 aaagcaagtg gactttgcac gtcatttgtg atagcaacaa caggtaaccc ttgtttttgt
     6661 atcattttta ctgcttcaac agtagaagca cttttcccgc tttgtgacac agcaatcaca
     6721 gtatcgattg aaggagaaag ttttccataa ttgaaaaaat aaaaaggttc ttgaatatcg
     6781 acagtaagat caccataaga ttccaatgct ggcttcgctg ctaaacaagc gttataagat
     6841 gaacccgttg ctaagatcag taaattcact gtttttttca tatgttctct tgtcgaaaaa
     6901 tcattctttt tcaagatcgt acttagtact tccttttctt catagatata atcttgcatc
     6961 gtaaacattt tctctgctcc ttttttaaaa aatccctatc cacgaaccaa aaattccaaa
     7021 gaaagctagt ccgatcaaga tcgttaatgg tttcacttct ttcttcaata gataaaacac
     7081 tatgccaaat gctccaagac ataagatatt tggaacgata tcatcaaaaa tactttgaac
     7141 agtcacagca ttttctcctg aaccgatttt taaaggaata ttgatggtga tcatcgtggc
     7201 agtcattgct ccaacgacca tcagtccaat aatagacgcg cctaatgtca aactttccat
     7261 cataccgttt gcctggatct ttttcaaaaa acccgttcct aagcgatatc cccaacctgt
     7321 tgctagatag cgaaacagaa tgtgcggaat attgaaaatc aaaatgaaca agatagggcc
     7381 taaaatattt ccttgcatgg ctaaagaggt acccacacct gtggcaatca atcgcaaagt
     7441 tccccaaaag aaagaatctc ctaaccctgc aagaggtccc atcaaagatg ttttgatact
     7501 atcgatcgca gtcacatcaa attcaggatc atccttattt tcttcctcca ttgcagccgt
     7561 gattcctaaa atcagtgtaa cgatatgtgg ggtcgtgtta aaaaactcta gatgccgttt
     7621 caaagctgct gccatttctt ctttcgactg atataacttt ttcaaaatcg gaatcattgc
     7681 ataaacataa gccatattca tctgacgttc ataattccaa gaaaactcca tttgaaaaga
     7741 acgccaaaat acgtgattta gctctttttt cgttattttg ctgtttttga tctcagaatt
     7801 cttcatcttc ttctacctcc cctgcagttg tttgaagtgg tagttgacgg acattcataa
     7861 tattgactac cacaactgct aaaatcgcac caaaaatagc tactccggtc acaggaatct
     7921 ctaagtaaga agctatagca aaacctaaga aaaaatatgg tgcaacttgt ttgttgatca
     7981 gcaaacgagc aagcatcgca aaaccaagag ctggaatcaa ccctgtagct actgacaacc
     8041 ccttttgaac gaagtcagga atcatattta atagatttcc gatcgtattg cttcccacca
     8101 tataagaaac cattaccaca acaccaagca tcaaggaaag accgataccg gcaagcaagt
     8161 gcatatgctc gactccttta taatttcctt cttctgcata attgtctgct ttatggttca
     8221 taattggaat caaaagccct aagtaaatat ttttcaatat caatgtcaac gtagcaatcg
     8281 gcaaacctag taaaagcgcg gtttctgtac cggctccagc tgtaatagca aaagccgtcc
     8341 ctaaaatccc accggtcaca acatcaggtg gaatcgaagc acctactgag aacgatccga
     8401 taaatgctaa ctctaaagtt gcgcccataa tgatcccagt ttttacatca cctaacacga
     8461 ttcctgtaaa cagccccgtc acaatcggac gagaaagcaa cgatgtccct agtgcatatt
     8521 ctgattgtgc gacaaatgca acaattccta ataagactgc ttgtacaatc attgaggttc
     8581 ttcctttctt acaaaacttc tcttacatcc acttttttat ctgctggtac ttgacggatt
     8641 tctacttcta tttgtttgtc aattaatcgt ttcaagcgtt cctcctcttc tggtaaaata
     8701 tttaccgctt ttccgatgct gcgagtacca ggttttgcct tgatccctcc taagttgatg
     8761 gttttgattt ctggatacgc ttctgccagc ttatatgcat cctcgatcga ttccactacg
     8821 atgaataact tatatttatc tgtcaccccg cttttcaacg cggcaatcga gtcatcaatt
     8881 gatttgatca ctagtttgac tccttgtggc ttggctaatt tgatcgttgt ctttcgtatc
     8941 tcattcgtag gtacatcatc attagcaatc aaaatacagt ctgcgcctat tgtttgtgtc
     9001 catgaaaaag ctacttgtcc gtgtaataac cgatggtcga ctcttgtcaa tacaatcatt
     9061 tttcttcctc ctaaaattcg tcttcttcta ttttctgatt gagccgctcg ttacaaaact
     9121 ggatcatttt ttttgaatca gttagcacct gctggatcaa aacagttgtc tctacttcag
     9181 cgtccaaccg agatactagc tcaatcaata gtggcaaatt caatccggca acgagataga
     9241 catgatcccg attgatatat tgtaagaatt cgttgttgac acttccgcca aaaagatccg
     9301 tcagaacaat gatttcttta tctttgtacc tcataaaaag ctgccttact gtttccgcta
     9361 aatcaaaatt ctcatcagta tagcaatcga atacagtaat agaatgattt ttcccataga
     9421 tcagctctaa tgaatctaat atccctgaag caaattttcc atgggaagct aagataattt
     9481 ctctatccac tttttcatct cctcttttca cttacacata ctaaaaaagc aagttgcatg
     9541 ccaaaattag tggcaacaac ttgcttatgt tcaaaattct tcttctatcg agagaaactc
     9601 tgtatcttca ctcaaaatat catagatata ggcaatctca gaattgggga tcatgacact
     9661 ataatgctct tcaatgacac taaacgcaga tttaatagca gataaccctt ctttttgaca
     9721 ctgcttccat ttctctaatc cttgataggt ttcgattggc atttgtcgga tcaatcgttc
     9781 aatgagacag ctcacatgga catacaacgc taattttttg ggattgctga tgcttcgatt
     9841 caactgcacc tctaattctc tcataaaatg atcgatttct cccatcacct tctctgtatc
     9901 tagaatagtc acggaatcca gtactttttc caatgaaaaa ttacgaatga tgcgctgatt
     9961 gaatatttcc ttctctgaag cattcatagt agtgtccaac cattcagcta gtacagacat
    10021 cttttccccc gagatgaggt cttctaatga aagatagtcg atattggtga tatcaggatc
    10081 tgtggtgcca atcattccta cgacttcgta tatggaaaat aatgggtcac tgtttttctt
    10141 atcttttaat tgctgatatt catatgggat gattttcaac tgacaagccg taggtaagct
    10201 tttttctagc agttcactta agtggaccgc cgtaccgatt ccagtgaagc aagtagtaat
    10261 gagtgctttg ggtttgtttt cctctggata gagcagtcgc cattctggct ggatctgtcg
    10321 aacagtctct tctgctatct cttctaatga tacatttttt tgcaggcatt cccctactgt
    10381 gattgctaaa ggtgtcgtca cattattcaa aatcaaaagc ggtacggata actgtttttt
    10441 aaaaaactga tggatttctt tcagagatcc catgtctact aatatgatca atccatttga
    10501 aacatcgctg ttttcgcaat aatcaaggat ttctgaagca atctgctgtg gtgtgacatc
    10561 tagtggcata tcaaatgatt caaatagatc ctcttgtaat aaacgattta ctacatttgc
    10621 catactgcta gcagttgcat aaccgtgagc agcaatcatc gcttttggca gtcgtttttc
    10681 ttttgaccat ttcgcttttt ttagatagat cgtcagtaaa atccgatcca tacttgtgtc
    10741 ttcaatatct aatttgatct tacttaattc cagaattcgt tggacatagt gataactaga
    10801 tggataagac tgagaaactt gttgttctaa ttctttgatt agttggataa tatcatgttc
    10861 ttccggtaac catttgatag tgcttcgctg atagagatag taactcaagg catagacact
    10921 gtttccatcg aatttgattt gataggcagt ttccatttgt cgaaaggtct ctcggataga
    10981 ttgtgtccaa taaaccagca gctcgtgttt ttcttgtcta ctggtctcaa acagcaaaaa
    11041 atcaaataat tgaatcactt cttgctttaa ttttccttcg caagaatata gcagacagtt
    11101 atttttcttg aaatcaatta ggatttgctc aaaactttta acgattcgct gctgttcggg
    11161 ctgttgcttc tccattaatt gctctaaggt ctggtcttgc gtaatataga ttccttgctg
    11221 tgctgtattt ttagtaatag gctgcgcaag tagttctttt tgcaaatgat ggatcgtgac
    11281 atggatttca ggctgttcac gctgttcagc atatgctttt gctgctgaaa ctttgacgat
    11341 atttttcagc tctcctatgt ttccggataa tttctgactt gttaaaagtg acaaagctgg
    11401 tccactgact gacaaagggc tccccatttt tctttgttct tcgagaaaaa aagagtaaat
    11461 cagttctagc cgttcattac gactacgctg attaagtgca ggtagttcga ttcggatagg
    11521 tattcttcga atgaaagttg ttaagaaatg actagtaatc tcttcagtcg tagcaaaaaa
    11581 gagacgtgtt ttgatccggc gtgacaaatt aggttctccc atacgataaa tcacaccttg
    11641 atcaagatag gtgaacagtt tttcctgacc ttctggtgtt aagcgatgta cctcgtctaa
    11701 aaacaagatc ccaccatctg ctgcttcaaa agcccctttt ttattttctt ctgcaccagt
    11761 gtacgctccc ttaacatgtc caaacaaatt gctagtcaaa agttcaggat tatctgcata
    11821 ttgtgcacaa ttaaaagtga tgaatggtgc agaatcttct agcagatcat gaagcagaca
    11881 atactgatag accaaattaa ctaaataact tttacctgtg ccactttcgc ctgtaatcaa
    11941 aagtggtaat ccgccatctg gatagtaaag agctgttttg atttgttcga tactttcttt
    12001 caaactggcg tcgtatccga tcataaaaga gaataagtct tttggttgcg cgaaaaaagg
    12061 ctgttcctct ttgagatcat cgatagaaaa ataaaaattc gtgcgtaact taaaaaattg
    12121 tttttcaaaa gcttctttgt ggaaataaat cactggtcga gaattgattt tgactagtag
    12181 ttgctcatca tttaactggt tcaaataatg actgactgtg tttcttttta ccccaaaatg
    12241 atcagctaac ctttgtgctg taaagacctc gttcatatgt tctaaatcga aaaaggctgt
    12301 ctggttctct aagtaacata aaatttcctt cttcaacaac ttattcaccc ctcctccatc
    12361 atagaaaacg gattcatttt gtcaataaaa tctttaataa agaattgaaa aatatatctt
    12421 attatagaca gcagcctact tatcccttat aatttttatt ctaaaaaacg tacagttcct
    12481 tccagttttt atactggaat ttcaacatat gaaagaataa ggaggctatg actattcaat
    12541 gaaatcggat aaatataaaa acaggaaaca tacttcctgg aaaacttttc gagaaatcat
    12601 cggatcttat ctcgctgtag ttgtattttt gcctttgctt tatatggcta tgacagaaca
    12661 aactcgtttt attggcgtag atacgcaata tatagccgaa acaggatttt tattcatctt
    12721 tatcttgatt tttgcgttct ataaatcctt ccatacaaaa taagattcac agatttcaac
    12781 tttcctgtct gtttttagct attacaaatc cttatatgtg gtataacaac aatttattgg
    12841 cataatgagg aaaaacgagt tatgatgctt tcagagagta aagaggtact gttgtcacca
    12901 tcctttttat tgattacgta caccactctt agttttttcc cattgattac gaaaacaagg
    12961 tagaaacatt gatgttccta ccttgttttc tttttttatt ttcagatcaa aatctcaagt
    13021 ggcttttgac ttgatgtcgg gaggttgtct tcgttccatc aaacctgata gaatctgcgc
    13081 caaaccatag ttttctccac tattatttat tcctctaaga tagtacccac aataaacgaa
    13141 taaatatttt tctcattttc atactccttc tttgaaaatc aattagattt ctctcaaccc
    13201 acttttttac aaaaattacg tagcaaaaaa gattgcaaga acaaattaaa aaagaagtaa
    13261 atagagtttc atctataaac atttacttga tatatttttt atgcagaatt catttataga
    13321 aaaattaagt aaaatagacg ttcctatgaa tgaagagact ggcatgtttt ctcattttct
    13381 tttttttaaa aaaaatagtc tattcaattt ctaaagcttc ttcataataa aactttcatt
    13441 tatgaaaagg cttgttctct tttcattcta aatttcctaa gctacaatgt ggtagtactt
    13501 gttttttcaa ttgtggacaa ataaataata ggaggaatca tatgattcag ttattacgtt
    13561 atgcaaaaga ctatcgtaag caaatcattt tgggcccgtt cttcaaattt cttgaagctg
    13621 tcttcgaact tgtcctgcct ttaatgatgg cttccttgat cgataatgga ctaaaaatga
    13681 atgaccgagg aaaaatcatt gaaatgggct tatggatggt cgctatgtct gtgattggtc
    13741 tgatttgtgc tatcatttgc caatactatg cttcagtagc ttcacaagga tttggtacag
    13801 agttacgtaa tcagctaatc aaaaaaatca atactttctc tcacaacgag ttgaatcatt
    13861 ttggaacaga taccttgatc acccgaatga caaacgacat caatcagctt cagctagctt
    13921 tagcaatggt cattcgttta ttgatcagag caccgttttt aagtatcggg tcagtggtca
    13981 tggcttttgt gatcgactgg gaagtaggtc tgtttttctt agcattattg cctattttct
    14041 caatcatttt attttttatc atcaaaaaaa ccgttcctct ctaccaaaaa gtgcaagaaa
    14101 aactagatca gctcaatgaa cacgttagtc agaatcttag cggtgttcgt gtcatccgcg
    14161 catttgcgca gacaaaaaaa gaaacagaga agttcgataa aagcacaaat gatctagcga
    14221 acaattattt acgtgtttcc aatatctctg ccctattatc acctgctaca accttgatca
    14281 tgaatgtcgg gatcatctgt ttgctgacag ttggcgggat caaagtaaat attggtagct
    14341 tgcaacaagg acaagttctt gctttgatca attatatgaa tcaaatgctt ttggcactga
    14401 tcgttgtttc aaacctcgtc gtgatcttca cacgtgccga agcttcagga aatcgggtga
    14461 aagaggtgct agacacagaa aattcgattc ttgaagctga ggtcagtact actcccgatt
    14521 tttcttctga agcaattatc gcttttgacc atgttgactt ccgttatact cctgattctg
    14581 gtctttctct ccaaaatatt acatttcagc tgaagcgaaa tacagtcctt ggaatcattg
    14641 gtccaaccgg aagcgggaaa acgactttga cacaattgat tccgcgtttc tatgatgtca
    14701 gttccggtac agttataatg gacggaatgg atgttcgttc ttggcagctg gatcatctcc
    14761 gtcagcaaat tgctcttgtt ccccaaactt ctgtactatt taccgggact attcgtgaaa
    14821 accttcaatg gggtaagaaa gacgccacag aaaaagaatg ttgggaagct ctgaaaatcg
    14881 ctcaggcaga agaatttgtc cgtcagcttc caaatggttt agatacaaaa gtcatggaaa
    14941 atgggaaaaa tttctctggc ggacaaaaac agcgactgac gattgcaaga gctttgattg
    15001 ccaagccagc attactgatt ttagatgact ctttaagtgc gttggattat caaacagact
    15061 tggatttgcg taaggcgcta cagacttatc ttggcagtac agtgattatt atctcccaac
    15121 gtgtccgctc tattcaagaa gcacatcata tcttagtgat ggatcaaggt aagattgctg
    15181 ctcagggtac ccatgaagaa ttacttgctc aatcagcaga atatcaggaa atcgtcgcat
    15241 cacaggagga agaatagtta tgaaagtaaa aaaattatcc ttgcagacgc tccgccgatt
    15301 cattccttac cttactgcct atgcaaaaga catttggcta gctgtgatac taggaatcat
    15361 caatgggatt gcaacagttg tgatgacgtt acaaattggt caaagtatcg atcaaatgat
    15421 tggagaagga caggtccgct tcaatcgact gttccattta cttattctat tcggtggtat
    15481 cgttttaatc aacgtagtca gtcaatggct catccaagtg ttaagcaatc ggttagctta
    15541 cttatccgtt gcaaaattaa gaaaagatgc atttgctcat ctgaatcgat tgccacttcg
    15601 ttattatgat caaaactccc acggaaatat cgtcagtcga tttacaaatg atatggacaa
    15661 tatttccatt gcaatttctg cggccttcaa tcaattattt tctggagtgg caatcatcat
    15721 tctttcgttt atttttatga tgcgtctaag tccacttctg acattggtcg ttctttgttc
    15781 tacaccaatt attttccttg tgagttggat cgttgctcgt gcttcacaaa caaatttcga
    15841 tagacagcaa aggattattg gggatatctc gggctttgtg accgaacgaa tcggtaacca
    15901 gaaaatcgtg aaagcttttc agcaagaaga agctagtcaa cagcaatttg aactgctaaa
    15961 tgctgatcta tatgaaaaag gacaacgggc acaattttct tcttccttga caaacccgtc
    16021 ttctcgtttt gtagatcacc ttgcttattt atcgattggt ttagttggcg gcctattggc
    16081 attgaagagt ggttcgtcaa tcactgttgg tgtgatttcc agctttacga tctactcaag
    16141 tcagttttct aaaccattta tcgaactttc tggaatcacg acacaactgc aaaccgcttt
    16201 ttctggtcta gaacgagcat ttgatttgat cgatcagcca gaagaaaagc ctgatttgcc
    16261 agatgcctat gccttggaac ccaaaaatat caaaggaaaa gtctcttttg atcatgtttc
    16321 tttttcttat gaccccaagc agcgtttgat cgaagatttc aattttactg cttatccagg
    16381 tcaaaccatt gctatagtag gaaaaacagg ggccggaaaa tccacacttg ttaatttgct
    16441 gatgcgtttt tatgacacaa caaaaggaac aattacagtc gatgaccatg acatccgctc
    16501 tatccaacgt gatacattac gtaaaagttt tggaatggtg ttacaagata cttggctatt
    16561 tgacagtaca ttgcgagaaa atcttcgttt tgggaatccg gaagcaagtg acgcagaaat
    16621 caatgatgcc ctaaaagcct cttatatgta tgaatttgta gaacgtttgc cggaaaaatt
    16681 agatactaag attggcggtc aagggttaaa gatatcagat ggacaacgcc aactgttgac
    16741 gattgctcga acgatgatca gtaatccccc tatgttgatc ttagatgaag ctaccagctc
    16801 agtcgataca ttgacagaga aaaaaatcca acaagccttc ttagcaatga tggaaggaaa
    16861 aaccagtttt gtgattgccc atcgcctgtc cacaatcaaa aatgcggacc agatattagt
    16921 gatggatcag ggagctattg tcgaaatggg cacccatgat gagctgcttc aaaaagatgg
    16981 ttattaccga cggctctatc aagcacaatt cacagcacaa taaaaacaag cagtcttctg
    17041 ggatgggaag actgcttgtt ttttatttag cgtggatcgc taaacttctt aaaatttt
//
LOCUS       DADVXE010000054        16716 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.055, whole genome shotgun sequence.
ACCESSION   DADVXE010000054 DADVXE010000000
VERSION     DADVXE010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16716
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.055"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(253..1464)
                     /locus_tag="KB913_002026"
     CDS             complement(253..1464)
                     /locus_tag="KB913_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6820368.1"
                     /translation="MSEVTGYLEQVDNETYRLRAVLGYKPDGSAKRKSKTIKASSKRA
                     AYKELNIWLEQFEGMTDDSLDLFNITFGEFYRKIWLSEAEKNLEPKSYHNYKRMIENR
                     FLDKFDFIPLIDIKPYMIKKIVVNAQRINTKDPGRNSDKPLSRNTKLRMLYAVNNLFL
                     MAKNEYGAIKENPVENVKIPKEKGVKKNIEEPYSEEEIHAMLKAAFEESIEIKTLIVL
                     AFITGARQGEIAALEEKDIDFDKQEIRFHQRISEVDGKSDIRLLPGLKNDDDEKIVTG
                     PAYLFDMLDELIKENKKIRWKLNIKKLKHYFIFDTKQDGTLPRGSYLYKKFKRFTKRH
                     NLRHIRFHDIRHTSATYLLSDPNMTPKELQKRLGHRDFNTTMNVYGHVLRKEKDTATT
                     AFENLLKKDIK"
     gene            complement(1583..2218)
                     /locus_tag="KB913_002027"
     CDS             complement(1583..2218)
                     /locus_tag="KB913_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBB6820369.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWVLIVLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTTKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAKNNVLQAQTGYFGTETVSIALHN"
     gene            complement(2354..3007)
                     /locus_tag="KB913_002028"
     CDS             complement(2354..3007)
                     /locus_tag="KB913_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820370.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETKISKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQVTAEPSPTVISSSQSTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFFKYGIQ"
     gene            complement(3110..3316)
                     /locus_tag="KB913_002029"
     CDS             complement(3110..3316)
                     /locus_tag="KB913_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HBB6820371.1"
                     /translation="MPSYVVLQVVLKEKFIGKGSQNLSELENTINRQCSKGYRLHTIS
                     TTNGGSKGFGGGDRIQATLVFESL"
     gene            complement(3392..4138)
                     /locus_tag="KB913_002030"
     CDS             complement(3392..4138)
                     /locus_tag="KB913_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004564412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820372.1"
                     /translation="MKQTTQQRLNQLMSERNLKQVDILNMSLPLQKETGIKMSKSHLS
                     QYVNGKSSPDQHKLYLLAKTLNVSEAWLLGYDVPKEDKKNNIPSIETIYNQLEKPRQT
                     KVYNFAEQQLEEQNRGNVVHFPKKEKLPTIKNSASAANPTELVYGDTVVEEEEFERVP
                     NNADFAVPIIGDSMEPVIRNGQFVFVKEQPDVEDGEIAIVEIDGDGVTCKEVYKDYES
                     QTIILRSINELYEDRVVSPEQIRIIGKVVF"
     gene            4298..4522
                     /locus_tag="KB913_002031"
     CDS             4298..4522
                     /locus_tag="KB913_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HBB6820373.1"
                     /translation="MSFDYSKLSGRIVEKYGTQYNFSIALGLSERSLSLKLNNRVPWK
                     STELQKAIELLDIPKEEIGEYFFNLEVQNV"
     gene            4546..5307
                     /locus_tag="KB913_002032"
     CDS             4546..5307
                     /locus_tag="KB913_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBB6820374.1"
                     /translation="MNTQKFENNLFELEVKTENGESLFNAETVARSLGFVETKNGKEY
                     VRWRTVNGYLKKYLSQEVAKNDFISEPMVYKLAFKANNVLAEKFQDWLATEVLPQIRK
                     HGMYATDELLNNPDLLIEVATKLKEERTLRLIAEQRVNELQPKADYYDRILNNKGLVT
                     VSTIAKNYGMSAVSFNKLLHELGIQFNQSGTWLLYSKFQDKGYTHIEPFDYEDKNGNR
                     QVKTRMKWTQKGHIFLYETLKKNNYLPMIEREQTA"
     gene            5319..5576
                     /locus_tag="KB913_002033"
     CDS             5319..5576
                     /locus_tag="KB913_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820375.1"
                     /translation="MNEEMSQTIKVQKMIDDLTHAIDSQADKIIKELQGQKVWDAKML
                     FKTIKFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            5668..5919
                     /locus_tag="KB913_002034"
     CDS             5668..5919
                     /locus_tag="KB913_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820376.1"
                     /translation="MEQLALVNLSDLKASLAESEIANEVWDTKQAAEYLKTTTRTLTK
                     DAESGKIPAAKVGREWRFSSIALYQYLKGGKTWVNSTEH"
     gene            5895..6068
                     /locus_tag="KB913_002035"
     CDS             5895..6068
                     /locus_tag="KB913_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820377.1"
                     /translation="MGKFNRALVFSAPLIVYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYRAKKPTEGAD"
     gene            complement(6182..6589)
                     /locus_tag="KB913_002036"
     CDS             complement(6182..6589)
                     /locus_tag="KB913_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820378.1"
                     /translation="MSFDNTITISIILALVALISPSITAVINNKHVESMKDKEIELQK
                     HDSKTQTIQTTFSTFLNNVGICIGSNTDKNISAVKASGYAVLPYIQNEDIEVMKIFLS
                     RFGYGNTDAEQKSLETYLIDKVLPILNKSLEKL"
     gene            6750..6974
                     /locus_tag="KB913_002037"
     CDS             6750..6974
                     /locus_tag="KB913_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820379.1"
                     /translation="MISVKGLGDEIFEAMMSKAQQDIKEKIISAAAQGQTSCTVRSRG
                     TTPSFLLALEDEGILNIKRRDGSVRLFWQF"
     gene            6984..7178
                     /locus_tag="KB913_002038"
     CDS             6984..7178
                     /locus_tag="KB913_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820380.1"
                     /translation="MKDFDSLGARQQPPNEASPVGVDWQENPLYPGDTCYLTEEGYVP
                     VDAILEYVQQHYPKIELGGI"
     gene            7181..8203
                     /locus_tag="KB913_002039"
     CDS             7181..8203
                     /locus_tag="KB913_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBB6820381.1"
                     /translation="MANDLTQTTQRSLDEQVISNLGRLQEQGLEMPPGYSPQNALKSA
                     FFELTNNTGGNLLQMAANNQEMKTSISNALLDMVIQGLSPAKKQCYFIKYGNKVQLMR
                     SYFGTMAVLDRVTGGADITPVVVRQGDEFEVAMDGPNMVVKKHETKFENLDNEIIAAY
                     VVIKLTNGKETTTVMTKKQIDQSWAKSKMKDSGPQKEFPEEMAKRTVINRAAKTLINT
                     SNDNDLLVQAAKDTLENEFDNDRKDITPQTEKVATLEQKFFSNKKITEPIQKEPDPIV
                     IPDDIQNEVTRVADVPAHPEIEQAHLIENEDINPIQEELIDIPDFGREEGVEDVSEFE
                     DDEYPF"
     gene            8166..8981
                     /locus_tag="KB913_002040"
     CDS             8166..8981
                     /locus_tag="KB913_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HBB6820382.1"
                     /translation="MSQNLKTTSTLSDENYYSNEADWQYMSTSQYKSFLKCEAAALAK
                     LKGDWAPTSDPKALLVGNYVHSYFESKEVHEAFKEENKSKMFSSRKPYGLLKDFQIAE
                     QMIERLKQEEAFMNIYQGEKETIVTGELFGTTWKGKIDCLNVEDEYFVDIKTTKDMHE
                     RKWNENYGSRETFIVNFGYVLQMAIYQELLLQQYGKMFMPIIAAVSKQTPSEAKLITI
                     DQDKMSYELIMLKENIERIVKVKNGEERPIPCGTCEYCRGNLSITGFTSMDDL"
     gene            8999..9781
                     /locus_tag="KB913_002041"
     CDS             8999..9781
                     /locus_tag="KB913_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820383.1"
                     /translation="MNLGYIKLYRKVTSSFVWTNSDMFKLWILCLMKASHEDRKFLFN
                     GQEVRLTSGQFVTGAHAIAKEYNEGVPSDKAIAWRTLWRWLKKFENEELLTIQSNARY
                     SVITIINWSDYQSSDKPVTSDGQSSDKPVTTNKNDKNDKNDKNNNPRNSRKTREYADD
                     DPNKKLAILLLKLIRKNRSLKEPDLNKWANTIRLTIEADKRTGKEVQDMIVWATNHDF
                     WSTVISSPTSLRKNFDTMVGQKNKRKQQNISNDELPETGEDW"
     gene            9781..10629
                     /locus_tag="KB913_002042"
     CDS             9781..10629
                     /locus_tag="KB913_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6820384.1"
                     /translation="MNKKLSAMAAPYGGLKTADHNCPKCGDPLYIWKTKNKDGTDRCG
                     PTCINKICGYREMVTKNQKEAIQKANEAMKKDAINRMLNSSMITDDAIWTFDFDGYKV
                     VDQETAQIKAMAQEWAKKIVNGSTIHAVITGRTGAGKTHLGAAVIKEVMRASNYKIAC
                     SFISYRELLEQLKFAMNDPEARKAVTGSLMAEIKKSDFVVIDDLGAELGRMEENNQAT
                     PYDVDVLTSLTEARLNKATIFTTNLSSKQLKHAYGERVFSRVMNGTKGNIAVFKTTTD
                     KRRNPV"
     gene            10626..10868
                     /locus_tag="KB913_002043"
     CDS             10626..10868
                     /locus_tag="KB913_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820385.1"
                     /translation="MTFVVKKMCYLDSRGRGEASVEFAKHHTTKEEADLVASVCGGEV
                     VEVIKPKRRFSKPKTKPVKKECCCPKSNQAWMRGAK"
     gene            11011..11379
                     /locus_tag="KB913_002044"
     CDS             11011..11379
                     /locus_tag="KB913_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBB6820386.1"
                     /translation="MATRSKYGNKKHEVDGITFDSITEAEYYDLALWQAQANGWKVKL
                     QERFELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQ
                     YQVPLILAKKYRNTFKEERF"
     gene            11394..11555
                     /locus_tag="KB913_002045"
     CDS             11394..11555
                     /locus_tag="KB913_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBB6820387.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            11552..11878
                     /locus_tag="KB913_002046"
     CDS             11552..11878
                     /locus_tag="KB913_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820388.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            11875..12690
                     /locus_tag="KB913_002047"
     CDS             11875..12690
                     /locus_tag="KB913_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBB6820389.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            12829..13140
                     /locus_tag="KB913_002048"
     CDS             12829..13140
                     /locus_tag="KB913_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBB6820390.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEGS
                     K"
     gene            13164..13382
                     /locus_tag="KB913_002049"
     CDS             13164..13382
                     /locus_tag="KB913_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820391.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            13379..13795
                     /locus_tag="KB913_002050"
     CDS             13379..13795
                     /locus_tag="KB913_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HBB6820392.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVIGNIYENSELLEVE"
     gene            13792..14130
                     /locus_tag="KB913_002051"
     CDS             13792..14130
                     /locus_tag="KB913_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820393.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMYGNSESAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            14127..14357
                     /locus_tag="KB913_002052"
     CDS             14127..14357
                     /locus_tag="KB913_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820394.1"
                     /translation="MKYEIPLSEADVQSIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            14364..14567
                     /locus_tag="KB913_002053"
     CDS             14364..14567
                     /locus_tag="KB913_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBB6820395.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASDAIRKFGISILSDDRKWEEKE"
     gene            14564..14860
                     /locus_tag="KB913_002054"
     CDS             14564..14860
                     /locus_tag="KB913_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820396.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWTAKSKENLAVVRLVDMELINDK"
     gene            14937..15350
                     /locus_tag="KB913_002055"
     CDS             14937..15350
                     /locus_tag="KB913_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBB6820397.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDALIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            15363..15749
                     /locus_tag="KB913_002056"
     CDS             15363..15749
                     /locus_tag="KB913_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820398.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
     gene            16300..16527
                     /locus_tag="KB913_002057"
     CDS             16300..16527
                     /locus_tag="KB913_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820399.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMLREAT
                     PKEIDQYKLVLIGIGWFKDEHIQTNMKRWLR"
     gene            16524..>16716
                     /locus_tag="KB913_002058"
     CDS             16524..>16716
                     /locus_tag="KB913_002058"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820400.1"
                     /translation="MKLYYVEKANCWVVEGCLSKYATDIISTQFSELGLKVIFCGEFV
                     SVKEAVLPMTAKSRRSRGSS"
BASE COUNT         5666 a         2726 c         3485 g         4839 t
ORIGIN      
        1 aataaaaaaa gaacagcgta aatgttttcg aaatgctttc gcaccaacat ttacctgttc
       61 cgtgggtttg gcacccaatg ggccgtgagg ggctcgaacc cgcgacccgc tgattaagag
      121 ttcgttattt aatggtattt taaatgaaga taagcgaatt tacagcattt ttaaatgctt
      181 atataccgca aattatccca agtttttgta tatcctaccc gagtttatac ccgaaaatat
      241 aattttttag tgttatttta tatctttttt taataggttt tcaaacgctg tagttgctgt
      301 atctttttct ttgcgtaaga catggccata aacattcatt gtagtattaa aatctcggtg
      361 tcccaatcgt ttttgaagct cttttggagt catattagga tcgctaagca aataggtagc
      421 tgatgtatgt ctaatgtcgt gaaaacgaat gtgacgcaaa ttgtgacgtt tggtgaatcg
      481 tttgaacttc ttatacagat aacttccacg tggcaaagtt ccatcttgtt ttgtatcaaa
      541 tataaaatag tgttttaatt tctttatatt taatttccaa cgaatctttt tattctcttt
      601 gattaattca tctaacatat caaatagata agcaggaccg gttactattt tttcatcatc
      661 atcatttttc aaacctggca gcaaccgaat atctgatttt ccatccactt ctgaaatccg
      721 ctgatgaaat cttatttctt gtttgtcaaa gtcaatatct ttttcttcta aagctgcaat
      781 ttctccttgt cttgctcctg taataaatgc tagaacaatt aaagttttaa tttctatgct
      841 ttcctcaaat gctgctttta gcattgcatg aatttcttct tccgaataag gttcttcgat
      901 attctttttt acgccttttt cttttggtat ttttacattt tccacaggat tttctttaat
      961 tgctccgtac tcatttttag ccatcaaaaa taagttgtta acggcgtata acatacgaag
     1021 ctttgtattt cttgataaag gtttatcaga gtttctccca ggatcttttg tattgattct
     1081 ttgagcatta acaacaattt tctttatcat gtatggtttg atatcgatta gagggataaa
     1141 atcaaattta tcaagaaatc tattctcgat cattcgctta tagttatgat aagactttgg
     1201 ctctaaattt ttttcggcct ctgaaagcca tatttttcta taaaattcac caaaagttat
     1261 attgaacaaa tccaacgaat catcggtcat tccttcgaat tgctctaacc agatgttcaa
     1321 ttctttatat gccgctcttt tactacttgc ttttatagtt ttgctttttc tttttgccga
     1381 gccatcaggt ttgtatccta atacagctct tagtctatat gtttcgttgt ctacttgttc
     1441 taagtatcct gttacttctg acataattga atcagctctc tttctctgat acaataggta
     1501 ctataaagaa gcctatcgta taggtttgtt tctttcttag aacacgctcg ctttggtcgg
     1561 tggggcgtgt tttttatact aattagttgt gaagagcaat tgaaactgtc tctgttccaa
     1621 agtaacctgt ttgtgcttgc aatacattat tttttgcatt tgcttgggct tcagagatat
     1681 caaaaactat tttaccagtt tgttgcatat caggatttaa gctttccata aagaaagagt
     1741 tagtgatatt accattttca tcttgatttg ccgacataga tgcagccgaa tcagcttcga
     1801 aagtttttcc atctgctttt aatttgaaga atgagctatc aacagtcaca gccttatcac
     1861 ctgcattttt tacagataag tcaactacta agaaagtgtc ttttgcgtta gtaggaagta
     1921 cagatgggcc aacttgtttt actacttcaa cggagtttac tttgtattcc attttcccta
     1981 cagcaacgtc atcaccgatt ttataagtct tttcttcttt tgttgtagtt tcttttgtag
     2041 tttctttatt agtacttgtt gatgttgcag tagctgaatc tttgttttca ccgccactta
     2101 gagcaccacc aataccaaaa aacaaaagta ctattaatac ccaaaaccat acccgtttat
     2161 aaaacggttt tttaacctta tacattttcc catcttgacc cataactttt tttgccattt
     2221 aaatattcct catttcttgt tataatatat ttgtgatctc agaaatgagg tatgagtccg
     2281 tgttgcagca cgggcttttt tatttataac ttttttagag attataggca aaatagtagg
     2341 gcataaaaat atattattga attccgtatt taaaaaatcc taattgaact tcaccggaag
     2401 tcttttgctg tgttgtacgc aatgcttctt cttcagacat tccattctgt actttccatg
     2461 caacaggcga catcccgtat ttgttaacaa aatcagtaag tgataaagtg tcagcgtctt
     2521 gctgagcgct tgtttgttgg tcttctggat tttgttgaga tgctgcttgt tgttctttct
     2581 gatcttgact gataatattg ccagcatcat ctgtagtcaa tccattttca taaagggcca
     2641 cgccgaaagc ttcccactct ttgttggacc aatttgcacg atcagctgga gttgactgta
     2701 aagtgcgttg tttcatctgt tcatatgttt cttcttgagg tgcggtttgg attgtactct
     2761 gactggagct tataactgtt gggctaggtt ccgccgtaac ttggttggag cttgtaactg
     2821 ttgaactaga atctgtttta gatgtagatt tgctagtaga tgaactggtt tcagttgttt
     2881 cttttgtttt acttattttt gtttcttggt tagaagtggc atctgttgat tcagcttttt
     2941 tattatttga acaagctgaa agtagcagag cagtacttaa caacaacata acgctaactt
     3001 ttttcatttt atactcctct tttctttgat acaataagtt gtaaagaagc ctactatagg
     3061 tttaacatcc cacgtccaca aactttggtc ggtgggcgtg tttttttgtt tatagacttt
     3121 cgaaaactaa agtagcttgg attctatcgc caccaccgaa acctttacta ccaccgtttg
     3181 tagtggaaat agtgtgtaat cgataacctt tagaacactg tctatttata gtgttttcaa
     3241 gttctgatag gttttgcgac ccttttccta taaacttttc ttttaataca acttgcaata
     3301 caacgtaact tggcatattc ttttccttct ttctactatg ataataaata ctaaccccta
     3361 gccggagcgc caactacgac tggggtattt tttagaatac gactttcccg attattctaa
     3421 tctgttccgg tgagacgact ctatcttcat ataattcgtt tatagagcgt agaataatcg
     3481 tttgactctc ataatcctta tatacttctt tacacgtcac accgtcacca tctatttcaa
     3541 cgatagcaat ctcaccgtct tccacgtctg gctgttcctt aacaaataca aattgtccat
     3601 tcctgataac tggttccatt gaatcgccta taataggaac agcaaaatca gcattgtttg
     3661 gaactctttc aaattcttct tcctctacaa ctgtatcgcc ataaactaat tcagtcgggt
     3721 tggcggcaga agctgaattt ttgattgtcg gaagtttttc ctttttagga aagtgcacca
     3781 cgtttcctcg attttgctct tcgagttgct gttcagcaaa gttgtagact tttgtttgtc
     3841 ttggtttttc taattgattg tagattgttt caatggatgg aatgttattt ttcttatctt
     3901 ctttaggaac atcgtaacca agcaaccatg cctcactcac atttaaagtt ttagccaaca
     3961 aataaagctt gtgttggtcg ggcgatgact taccattgac atattgcgat agatgacttt
     4021 ttgacatttt tattccagtt tctttttgca aaggtaaaga catattcaaa atatcaactt
     4081 gctttaaatt tctttcagac attaactgat taagtcgttg ctgagtcgtt tgcttcatct
     4141 tatacctcct ttctgatact tattatatac cttattgaac ataagttcaa taaaaaagtt
     4201 aaattaattt gaacttttat gttgacaatg ttttatgcag gagttatact ttggttacaa
     4261 agttcaaaac atttgaacta gaaaggagcg aactaatatg agttttgatt attctaagtt
     4321 gtcgggaaga attgttgaga aatatggaac gcaatacaat ttttcaatcg ctttaggttt
     4381 gtcggaaaga agtttgtcat taaagttgaa taaccgagta ccatggaaaa gcaccgaact
     4441 tcaaaaagcc attgaattgc tagatattcc aaaagaagaa attggcgaat atttttttaa
     4501 tttagaagtt caaaatgtct gaacttaaga aaggaattcg aaaaaatgaa cacacaaaaa
     4561 tttgaaaaca atctatttga attagaagtt aagacggaaa atggtgaatc gttatttaat
     4621 gctgaaacag tagcaagaag tttgggtttc gtggaaacaa aaaacggtaa agaatatgtt
     4681 cggtggagaa ctgtcaatgg atatttaaaa aaataccttt cgcaagaagt tgcgaaaaac
     4741 gactttatca gtgagccaat ggtttacaaa ttagccttta aagcaaacaa cgtacttgct
     4801 gaaaaattcc aagactggtt agcaacggaa gtcctacctc aaatccgaaa acacggcatg
     4861 tacgcaacag atgaactact taacaatcca gacttgctga ttgaagtagc aaccaaactc
     4921 aaagaagaac gcacgttacg attgatagct gaacaacgag taaatgaatt acaaccgaag
     4981 gcagactatt acgaccgaat cttgaacaac aaaggattag ttacagttag tacgattgct
     5041 aagaactacg gtatgagcgc tgtatcgttt aataaattgc tacatgaatt aggtatccag
     5101 ttcaatcaaa gtggcacatg gctgctatac agtaagttcc aagacaaagg atacacgcat
     5161 attgagccat ttgattatga agataaaaac ggcaatcggc aagtaaaaac aaggatgaaa
     5221 tggacgcaaa aaggacacat cttcttatat gaaacattga agaagaataa ttacttaccg
     5281 atgattgaac gtgaacaaac agcataggag gtaacactat gaacgaggaa atgagccaaa
     5341 caatcaaggt acaaaaaatg atagatgatc taacacatgc aattgatagc caagccgata
     5401 aaatcatcaa ggaattgcaa ggacaaaaag tttgggatgc aaaaatgctt ttcaagacta
     5461 tcaaatttga aatgaatcca acaaaaagaa agctcgccga tgtgttggaa gaaaagttgg
     5521 cttccgctat caacgagcaa gaattactat ttgaaaccga tacttttaac agctgatgtt
     5581 ttatagatga cagtttcatc cgaatctata tcattataga ttcgattatt gcaatgtacg
     5641 aattataaat acaggaggaa ataaccaatg gagcaactag ctttagttaa cctctcagac
     5701 cttaaagctt ctttggcaga atctgagatt gcaaatgaag tgtgggatac aaagcaagct
     5761 gcggaatatt taaaaaccac aacacgcacg ctgactaaag atgccgaatc tggaaagatt
     5821 ccagcagcga aagttggcag agagtggagg tttagtagta tcgctttgta tcagtatcta
     5881 aaaggaggaa aaacatgggt aaattcaaca gagcactagt gttcagcgca cccctaatcg
     5941 tctatgcttt aggactttgg ggaagcagac aagcattaat cggcacgatc gtttacatgg
     6001 tttggatttt tatggggctt gatgaagctg agtacagagc gaaaaagccc accgaggggg
     6061 ctgactaaag tgtggttctg tttattaggt gtttatctcg tggccgtttt agtaaataac
     6121 tacatgagaa aacgtggcga atactggtat acatcctatg cggttctagt atgtctaatg
     6181 cttacaattt ttctaatgat ttattcaaaa taggtaatac tttgtcaatc aaataagttt
     6241 caagagattt ttgttctgca tcagtgttgc cgtaaccaaa acggcttaag aaaattttca
     6301 taacctctat atcttcattt tgaatatatg gcaggactgc ataacctgat gcttttacag
     6361 cagatatatt tttatcagtg ttactaccaa tacaaatacc cacattgttg agaaatgttg
     6421 agaaagttgt ttgtattgtt tgggtttttg aatcgtgttt ttgtaattca atttctttat
     6481 ccttcatcga ttcaacatgc ttattattta taaccgctgt aatcgaaggg gatataagag
     6541 ctactaaagc taggataatc gaaattgtga tcgtgttatc gaaactcatt ttttcaccat
     6601 ccagttttta aaccattata tcaaaaagga gagaagaaat aatgcaagaa ttagtaattt
     6661 tgaaaaataa aaaaagacac gaacgccagc aagcatgatc gtgtccaaaa gaaaaatctt
     6721 ttaaaccatt ataacacagg aggaaataaa tgatctcagt taaagggtta ggcgatgaaa
     6781 tattcgaagc aatgatgagc aaagcacaac aggacatcaa agaaaaaatc atttctgctg
     6841 cagcgcaagg acaaactagc tgcactgttc gatcgagagg aacgacacca agttttcttt
     6901 tggcgctaga agatgaaggc attttgaata tcaaacgaag agatggcagc gtcagattgt
     6961 tttggcaatt ttaggaggcc gtgatgaaag attttgattc tttaggcgcc agacagcaac
     7021 caccaaatga agctagtcct gttggagttg attggcaaga aaatccgtta tatccaggtg
     7081 atacttgcta tctaacagaa gaaggctatg taccagtaga cgcaattcta gagtacgtcc
     7141 agcaacatta tccaaagatt gaattaggag gaatttagga atggcaaatg atttaacaca
     7201 aacaacacaa cgttcattag atgagcaggt aatcagtaat cttggacggt tacaagaaca
     7261 aggtttagaa atgccaccag gatatagtcc acaaaatgcg ttaaaaagtg cttttttcga
     7321 actcactaac aatacaggag gaaacttgtt gcagatggct gcaaacaatc aagaaatgaa
     7381 aacctccatt tctaatgcac ttttagacat ggttattcaa gggttatctc cagcaaaaaa
     7441 acaatgctat ttcattaaat acggaaacaa ggttcagcta atgcgttcat attttggaac
     7501 aatggcggtc cttgatcgtg taactggagg ggcagatatt acgcctgtag tcgttcgaca
     7561 aggtgatgag tttgaagttg caatggatgg accaaacatg gttgtcaaaa agcatgaaac
     7621 aaaattcgag aatttagaca atgaaatcat tgcagcctat gtagtcatca agttaacaaa
     7681 tggtaaagag accacaacag tcatgacgaa aaagcaaatc gatcaaagtt gggctaagtc
     7741 aaaaatgaaa gattctggac cgcaaaagga atttccagaa gaaatggcta aacggacagt
     7801 aatcaatcgg gcagctaaaa cattgatcaa cacaagcaac gacaacgatt tattagttca
     7861 agctgcaaaa gatacgttag aaaatgaatt tgacaatgat cggaaagata taacgccaca
     7921 aacagaaaaa gtggctactc tcgaacaaaa attcttttca aacaaaaaga ttactgaacc
     7981 aatacaaaaa gaaccagatc cgattgtgat tccagatgat atccaaaatg aagtaactcg
     8041 agttgctgat gtacctgccc atccagaaat agagcaagca catttgatcg aaaatgagga
     8101 tatcaatcca attcaagaag aattgataga tattccagac tttggacgcg aggaaggtgt
     8161 agaagatgtc tcagaatttg aagacgacga gtaccctttc tgatgagaat tattactcca
     8221 atgaagctga ctggcagtac atgtcaacat cacaatataa gtccttttta aaatgtgaag
     8281 ccgcagcctt agcaaagttg aaaggcgatt gggcaccgac gtcggatccc aaagccttac
     8341 tcgtaggaaa ctacgtacat tcttattttg aatcaaaaga agtacatgaa gcgttcaaag
     8401 aagaaaataa atccaaaatg ttttctagta ggaagccgta tggattgttg aaagatttcc
     8461 aaattgctga acaaatgatt gaacgactta agcaagaaga agcattcatg aacatttatc
     8521 aaggtgagaa agaaacgatc gtgactgggg aactatttgg aacgacatgg aaaggcaaga
     8581 ttgattgctt gaatgttgag gatgagtatt ttgttgatat caaaacaacc aaagacatgc
     8641 atgagcggaa atggaacgaa aactacggat caagagaaac gttcattgtc aattttggtt
     8701 acgtacttca aatggcaatc tatcaagagc ttcttttaca gcaatacgga aagatgttca
     8761 tgccaatcat cgctgcggta tcgaagcaaa cgcctagtga ggcgaagttg ataacgattg
     8821 atcaagataa gatgagctac gagctaatca tgctaaaaga aaatattgaa agaattgtca
     8881 aagtgaaaaa tggcgaagaa aggccgatac cttgcggtac gtgcgagtat tgtcgaggta
     8941 acctttcaat tactggattc actagcatgg acgatcttta aaaggaggtg ctttgcgaat
     9001 gaatctagga tacatcaagt tataccgtaa agtgactagt tcattcgttt ggaccaattc
     9061 cgatatgttc aagctatgga tattgtgttt aatgaaggct agtcatgaag atagaaaatt
     9121 tttatttaac ggtcaagaag tacgtttgac aagcggacaa ttcgtcacag gagcccatgc
     9181 aatagcaaaa gagtacaacg aaggagtccc gagtgacaaa gcaattgcat ggcgaacgct
     9241 atggagatgg cttaagaaat ttgaaaatga agaattattg acaatccaat cgaacgctag
     9301 atatagcgtt ataacaataa taaattggtc tgactatcaa tcgagtgaca agccagtgac
     9361 aagcgacgga caatcgagtg acaagccagt gacaacaaac aagaatgata agaatgataa
     9421 gaatgataag aataataatc ctcgcaactc tcgaaaaaca cgagagtatg cagatgacga
     9481 tccaaataaa aaattggcca ttcttttatt aaaactcatt cgaaagaatc gtagtctcaa
     9541 agaacccgat ttgaacaaat gggccaatac gattcgtttg acgattgaag ctgacaaacg
     9601 aactggaaaa gaagttcaag acatgattgt ttgggctact aaccatgatt tttggtccac
     9661 agtcatttca tcgccaacta gcttaagaaa aaatttcgat acaatggtgg gtcaaaaaaa
     9721 taaaagaaag caacaaaata tttctaatga tgagttacca gaaacaggtg aggattggta
     9781 atgaataaaa aactaagtgc aatggctgca ccttacggcg gattaaaaac agcagatcat
     9841 aattgcccga aatgtggtga tccattgtat atctggaaaa caaaaaataa agatggtact
     9901 gatcgatgcg gtcctacatg tatcaataag atttgtggtt atcgagaaat ggtaactaaa
     9961 aatcaaaaag aagctatcca aaaagcgaat gaagcaatga aaaaggacgc tatcaatcga
    10021 atgcttaaca gttcaatgat tacagatgat gccatatgga ccttcgattt tgatggatac
    10081 aaagtagttg atcaggaaac agcacaaata aaagcgatgg ctcaagaatg ggctaaaaaa
    10141 attgtaaatg gtagcacgat tcatgcagtg ataaccggta gaacaggagc cggcaaaacc
    10201 catctaggcg ctgcagtgat taaagaagtc atgagggcat ctaattataa aattgcttgt
    10261 tcatttatca gttatcgaga acttttagaa cagttgaaat ttgcaatgaa tgatccagaa
    10321 gcaagaaaag ccgtaacagg ttcgctgatg gctgagataa agaaatcaga tttcgtggta
    10381 atcgacgatt tgggtgcaga actaggaaga atggaagaaa acaaccaggc aacgccttat
    10441 gatgttgatg ttctcacatc gctcacagaa gctcgtctaa acaaagctac gatattcaca
    10501 accaatttat catcgaagca attaaaacac gcgtacggtg agcgagtgtt ctctcgtgta
    10561 atgaatggaa cgaaagggaa catagctgta ttcaaaacaa cgacagacaa aaggaggaat
    10621 ccagtttgac ctttgtagtg aaaaaaatgt gctacttaga tagccgaggg cgaggagaag
    10681 ctagtgtcga gtttgctaaa caccacacga ctaaagaaga ggctgacctt gttgcaagtg
    10741 tttgtggcgg cgaagtagtc gaagttatta aacccaaaag acgattttca aaacctaaga
    10801 caaagccagt gaaaaaagag tgttgttgtc cgaaaagtaa ccaagcatgg atgagaggtg
    10861 caaaatgact tgtttaaaat gcaacgatga aacagttatt tggtataaga cattgcttgg
    10921 atggtcaact tgtgaacctt gtccaatatg caatgaaaat ggacgacgtt cgaaagaacg
    10981 actcgaaaga ctaaagaagg agtatagcaa atggcaacaa gaagcaaata cggaaacaaa
    11041 aagcacgaag tagacggcat cacttttgat tctatcacgg aagcagagta ttacgatcta
    11101 gccttgtggc aagcacaggc gaatggttgg aaagtgaagc tccaggaaag gtttgagctg
    11161 atgccgaagt ttgaactaga gggcaagaag tatcgcaaga tcgagtatat tcccgacttc
    11221 acattttaca aaagcggcaa gctggtcaaa gtcgtagatg ttaaggggat gcagacaaaa
    11281 gactttaaga tcaaggcaaa gttgttctgt catcaatatc aagtgccgtt gatattagcc
    11341 aaaaaatatc ggaatacgtt caaggaagag cgtttttaac gaggtggtcc atcatgacaa
    11401 cagaagaagt gattcaaatg cgaattcgaa gccttcggcg tgagattgac gatctggaac
    11461 gaacaaaggc agtgatggtc aatgaaacgg ctagaaaggc aatcgatttg cacatagaga
    11521 atttaagaag ggaaatccgt agattggagg aatgagcgtg gataaggaag cggcttggcg
    11581 aaaattaatg ttgctgattc aagatgagaa ctggcaagaa gatgaagcag tggttgctga
    11641 agttcagcgt ctaggaaaga ttgctaacgg acgtatacga aaaaagccag acaaaagaaa
    11701 acagcgcaaa gggaaaatcg tcgttgtttt acacgaaggc aaaattttga tgcaaggaac
    11761 agctagtgag ctgtctgcag aaactggata tacgcgtggg actattcgaa cgtacgcttg
    11821 gcgaaatcac accgatcgaa aagggcacga atataagtat ttggaggaag aaaaatgaac
    11881 gaaaacaaat taatcaaatt gggtgtagca ggagcagtaa tcgtaggtat tggagttatc
    11941 ggaggattta agttcttcga aaaaatcgat aatggatatg tgggtgtgcg ctattcaatg
    12001 aacggcggta tcaaagatga agcactgacg caaggtgtga aatttgtagg gattgacaaa
    12061 gtgatccaat atccaattcg cttgcaaact atccaatcaa aaaatatttc agtatctaca
    12121 agcgacggca aaaagacaac gattgatatc aaatatgact acaaagttga ttcaactaaa
    12181 gcagcaaaaa tgtacaagga atttgggaat atcacttcgg aagatatcga aagtggatgg
    12241 ttaaaatcta agcttcaaaa ggtcgctcgt gaagtttatg cgaaatatag tctgcttgat
    12301 gtcctttcag gagattcctc taaagttgaa gctgaggtat taacgaactt tgctaaatca
    12361 gttgaatcta aagggtttga agtcgaagac gtaacacttg gtgttccaga tgtcgataaa
    12421 gaaacacaaa aatcaatcga tgcgatcatt cgagctggtc aagaaaatga aaaagcgaag
    12481 ctagacgcag aaactgcaaa aactcaagct gatagtgaag cttacaagaa aacaaaagct
    12541 gcagaagcag aggcagaatc taatcgcaaa gtcgccgaat cagtaacaga caatttgatt
    12601 cgttatgaag aagctcaagc tcgcaaaaag catggatggg taacagtaaa tggagcagat
    12661 actgtagtta cggatgaagc aggcaaataa tatgggattc tttatggcta aaattctctt
    12721 gttcttaggt ttagtaggag cagcatatct cgtgtatgcg ctcctttccc aaactgatga
    12781 caaagaagat gacaacaacg atgaaatgaa attttaggag gagaaataat ggacgaacta
    12841 atcacaaaag tagagcagtg ggctaaagac aagggactgg atcaagcaga tccaaaagca
    12901 cagtttttga aagtagctga ggaattcggg gaaatagctt cggcgatggc aagaagtaat
    12961 gatgaactat ttaaagatag cgtaggagac gttatcgtca cgctgattat cctttccatg
    13021 caaaaaggga caaacgtaca agagtgttta gaaatggcat acaacgaaat caaaggacgc
    13081 acagggaaaa tggtagatgg tgtattcgtg aagtcgagtg atttggaggg cagcaaatga
    13141 taaaaaagct cattcaattc agcatggatt tatatgatat cgaatcagga gcaacactat
    13201 ctgtggaatc ggaccatcta atcataaatt ttggtggaaa gcgccagatt attttgtggg
    13261 tagttgatga tgtactgttt ccagaaattg ttcatgattt cgaagaatca aaagcggttg
    13321 agtttgaaat agtgaaaaaa gtaatggaat tgattgaaaa atacgaggag gacagcgaat
    13381 gataccgaag tttagagcgt gggataaacg aaagaacgta atgagagatg tagccgtctt
    13441 gcattttact aaaaacggca aaacaaactt tattgaatat tggataaatc ctaccgaatt
    13501 gaaatcatat cacgtgcgaa acatcgacct catgcaatcc acaggaatga aagataagaa
    13561 tggtgtggat atatttgaag gggatatagt attagtcagc gtgcgaaatg gcttcgatta
    13621 cttagataat aaagtttgta ttgtcaaaaa ttcaatagat tattccggat tagtttgtgc
    13681 cactgttgat gaagacttag agtatcaaat ttttaacaca gagctgtttg aagaatacac
    13741 gtatgaagtc atcggaaata tatacgagaa tagcgagtta ttggaggtag agtgattatc
    13801 ttagctactg actacatcga ttctttaaaa gatgaaaatg ggaatgtccc agcattgcta
    13861 aattgtggaa ttaaaagcaa gaatagaatc attttgttac ggatatcggc tgatttagca
    13921 aaatatcttt atctgagcaa gacagcagta tattacactg cggctacacg ttatcagtac
    13981 aagggaaaaa caatcagtca ggattattat gatcgtttaa tcagtcctga tatgtatggg
    14041 aattcagaat cagcaattaa gctgtttggc gcaatagaga tatatgccga tgattttcca
    14101 aatttatggt tgaaggagga agcggaatga aatacgaaat accactaagt gaagcagacg
    14161 tccagtcaat tattaacggt cgggaggtta ataaaaaact tcctgatggt actgaattag
    14221 tcatcagaca aagttatttg aaagatatgg cagctccagt attaattgat cgttttaacg
    14281 tgactgattc tgtggtagag aaccacttga aagaatttcg atcaagtata aacgacactt
    14341 tcagattagg gagttgattg acaatgaaca ccagacaccg cagagtagca aaactaagaa
    14401 aacaggaact gaatgtacta aagacaaagt ttgaaaaaga atatggaatt tcagcagaag
    14461 aaacatataa agtggcaagt cagtgtgttg ctgatgcaag tgatgctatt cgtaagtttg
    14521 gaatttcgat attaagtgat gatcgtaaat gggaggaaaa agaatgaaac taaaagacgg
    14581 attttacgct agcagtcacg gtatcggcgg tttaatgcta gatatgccga caaagaatcc
    14641 taaaacacgt aagaaaccaa aagtcaaagt cggtgacatg gtccgctgtg aagcagagga
    14701 gttcatttat ccatttcgtg gatatgtaga acacgtctat aatcactcag cgatcattcg
    14761 cattgaaaac acgatggaat gtgataaatg gacagctaaa agcaaagaga atttagcagt
    14821 agtgagattg gtggatatgg aactaatcaa tgacaaataa aaaagccgga tcgctccgac
    14881 taacataata aaacagacaa gtttattata tcacataaaa ggagcagttt gaattgatgc
    14941 aattgttacg agaggtagat ttcaaacaga caagatgtaa tgcgagagat gtgctgaaga
    15001 actttcggcg tttggagcgg atggcaggtc gctctttgat agatattaag tcgccgatta
    15061 ttacggatat gccgaaggca ccgaagcacg gcaataaggc agaggatgca ttgattcaga
    15121 tgatggatat agaagcggag agagacgcga ttttagcggc tttgatggct cttagtctga
    15181 ttagtcgtca gatactctac tacagttttt gtgtgccaga cagcttctca aactacagaa
    15241 ttagccgtga agtgggttat tcagaaagaa gtatacaacg gatgaaatcg gaagctctaa
    15301 tagagtttgc agaagcatat aaacacggaa gaataattgc ttataaatag ggggaccata
    15361 taatgtggaa agattatgta tcgttgaaag agttgaaaaa agatcttgtt ttcaaaagaa
    15421 ttgtagaatg gtcagagagt gaattaattt tagaagatgg aaccaaaatg gaagttgtat
    15481 gtagcgaatc agattgctgc gcatgggccg aaggtgaatt caaaaatgta aagcttgatg
    15541 cagtgattac agatataaag atttttgata aaggtaaccg tctctataat ggtgacggac
    15601 atacctctta tgctgaagtc gttgtttatc ataatcgtaa tgagatcgct aaagcagaat
    15661 gcacagcgaa tgatgggaat ggcggctact attatagtgt ttgtgcttta aaggtcaaag
    15721 acaaactttg tatagtgact gacgcataaa aaaatggcgg ttttttggcg gaatgatggc
    15781 ggtttttagc catttatcag tgatattatg gtagtgtcga aagattagtg ataggtctga
    15841 gacaaaataa taataaaagg aacatcgttt tattattgtt tcacaattaa gcttcgatag
    15901 acagcaacgg aaatattaag aataaggatg tgaattttaa ctccttctaa attgttctta
    15961 ttatctatca tccgttgctg tttattgtta catacagatc gcttaggcgg tctttttatt
    16021 ttggccgaaa acctacattt tcgatggccg attattggag gaggaatagc atgttcaaac
    16081 tatctgaaat cattaagaag tccgacgttg agaaattaga gatgttaaaa aagaagttga
    16141 agaaatagca gtctcttcgt gaggctgttt tattttgctc acaaaaatag accactatcg
    16201 ggtaatagtg gtcaggaatt aaatgaaaaa gatgttaggg ttgttagcta agtataacat
    16261 cataacgctt acaaaacaat gcaagaagga taaattatta tgagaactta ctggtatgtg
    16321 tcattaaaca ataaatatcc gaagccaatg aaaggacagc ataggcgtgt agtcatgtct
    16381 gttcaaatga aggcgaagta ttcgattgta gaaatgctaa gagaagctac accaaaagag
    16441 attgatcagt ataagttggt tcttattggc attggttggt ttaaggatga acatattcaa
    16501 acaaacatga agaggtggtt gagatgaagt tatattatgt tgaaaaagca aattgttggg
    16561 tggttgaagg ctgtctgtca aagtacgcta cagatattat atctactcaa ttttcagagt
    16621 tgggattgaa ggttatcttt tgtggtgagt ttgtcagtgt gaaagaagcg gtattgccaa
    16681 tgacagcaaa gagcagacgc tcgcgtggtt caagtt
//
LOCUS       DADVXE010000055        16692 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.056, whole genome shotgun sequence.
ACCESSION   DADVXE010000055 DADVXE010000000
VERSION     DADVXE010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16692
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.056"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            127..270
                     /locus_tag="KB913_002059"
     CDS             127..270
                     /locus_tag="KB913_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBB6820401.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            848..2431
                     /locus_tag="KB913_002060"
     CDS             848..2431
                     /locus_tag="KB913_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6820402.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIVLVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(2868..4052)
                     /locus_tag="KB913_002061"
     CDS             complement(2868..4052)
                     /locus_tag="KB913_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBB6820403.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(4077..5084)
                     /locus_tag="KB913_002062"
     CDS             complement(4077..5084)
                     /locus_tag="KB913_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6820404.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            complement(5256..5615)
                     /locus_tag="KB913_002063"
     CDS             complement(5256..5615)
                     /locus_tag="KB913_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820405.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            complement(5587..5958)
                     /locus_tag="KB913_002064"
     CDS             complement(5587..5958)
                     /locus_tag="KB913_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBB6820406.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            complement(5975..6277)
                     /locus_tag="KB913_002065"
     CDS             complement(5975..6277)
                     /locus_tag="KB913_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820407.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            complement(6294..6764)
                     /locus_tag="KB913_002066"
     CDS             complement(6294..6764)
                     /locus_tag="KB913_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBB6820408.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            complement(6739..7017)
                     /locus_tag="KB913_002067"
     CDS             complement(6739..7017)
                     /locus_tag="KB913_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBB6820409.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            complement(7014..8063)
                     /locus_tag="KB913_002068"
     CDS             complement(7014..8063)
                     /locus_tag="KB913_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBB6820410.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            complement(8020..8949)
                     /gene="tadA"
                     /locus_tag="KB913_002069"
     CDS             complement(8020..8949)
                     /gene="tadA"
                     /locus_tag="KB913_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBB6820411.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            9081..10835
                     /gene="ade"
                     /locus_tag="KB913_002070"
     CDS             9081..10835
                     /gene="ade"
                     /locus_tag="KB913_002070"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBB6820412.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            complement(10933..11595)
                     /gene="trmB"
                     /locus_tag="KB913_002071"
     CDS             complement(10933..11595)
                     /gene="trmB"
                     /locus_tag="KB913_002071"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBB6820413.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(11665..12447)
                     /locus_tag="KB913_002072"
     CDS             complement(11665..12447)
                     /locus_tag="KB913_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBB6820414.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            complement(12651..13862)
                     /locus_tag="KB913_002073"
     CDS             complement(12651..13862)
                     /locus_tag="KB913_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6820415.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            complement(13855..14592)
                     /locus_tag="KB913_002074"
     CDS             complement(13855..14592)
                     /locus_tag="KB913_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820416.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            14730..15164
                     /locus_tag="KB913_002075"
     CDS             14730..15164
                     /locus_tag="KB913_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBB6820417.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            15157..15501
                     /locus_tag="KB913_002076"
     CDS             15157..15501
                     /locus_tag="KB913_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBB6820418.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            15681..16691
                     /locus_tag="KB913_002077"
     CDS             15681..16691
                     /locus_tag="KB913_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6820419.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
BASE COUNT         5323 a         3417 c         2940 g         5012 t
ORIGIN      
        1 tttaaaataa agggaaaaca gtcaatgagt tcaagtaaaa taaaaaaaag tgaacaccag
       61 ggcgattagt cgccctggtg tggtttaaaa cgacctaagc atgccaaagc ttattggttc
      121 gtcaatgtgg aagtttccga tgaatctgat acgaaaaaat atgaagtatc gatggcggat
      181 accgatttta tcgccaaact aaaattttat ttcgggttcg ggtaccgcga gaaggcaagt
      241 gctacattcg gtaaatcatt caagaattga tgaaaggcta ccgcttgcca ttgcaaccac
      301 aacgatactc ctgaacgcga tgttggtgag atttccaaag agaagagctg tttaatgcaa
      361 cggtattaag caaatggcaa aaggaagtca tgtagacaaa gttttttatc aaacaccata
      421 tgatttcgcc tgaacgctgg tttagctcag aatacaatga tgtggtccac gagacattac
      481 cctcagtcag ataaaaaaag ctctctgaca gaattacaca tcgataaata ttaagtaaat
      541 gtcagcgcta gttgaacttt ctgacacttt caggtacact ggaaaagaca actacacgaa
      601 ggagggaaaa tactatgatg cgcatgacta aaataacaag taatgaaaat taccaacgat
      661 accatatcgc atttagccat gcaattggtt ttacagttgc tgttgacggg acaagtttgt
      721 ccaaaacagt tgaattcacg taaaatcaat ggccatctca aggtattttt ctcatgataa
      781 tctgagttta aataacacag gccatggata accatggcct ttttgagtgg tctcaaggag
      841 agagatcatg atcatacaag caatttctat taaaaaaaca atcggcggga atccattatt
      901 tgaggattta tcctgtcaaa ttgaagctgg tgaaaaaatt gtcttagtcg gtatcaacgg
      961 aactggcaaa tcaacctttt tacaaatctt gaccggcaga gaaggtgtcg acagcggtgt
     1021 tatcagtcgc aaaaaaggct taaagatcgg gacggtcgaa caagaactta cagtttccga
     1081 agcgaccgtc aaccactact tgctccattc tgccgctgag atacaggacc tcaaacagca
     1141 aatgagtcgc tacgaagcat tgatgacaga accagataca aacttagaga agtgtctggc
     1201 ccgttacggt gagctgcagc atcgctttga agaactaggc ggttacgtat tagaagaccg
     1261 gattgcagcg atcttgcaag gcttagggat tccacaccgt caggaagcac ggttaacaga
     1321 acttagcgga ggcgaacgag ttaaagtcgc tttagccaaa attttagcag ccgatgccga
     1381 tttactttta ctcgatgaac cgaccaatca tttagatctt aacagtattc gctggttgga
     1441 aaactattta cagaatacaa aaaaatcggt tctggtcgtt tctcatgatc ggcaatttct
     1501 cgatcaagtc accacaaaaa catgggaact ggaagaaggt gcattgattg agtatcccgg
     1561 aaactacagc cgttttcgag tcttgaaaga agctcgcttg gctgagctga caaaaaatta
     1621 cgaactgcag caaaaagaag tccagcggtt gaaagtcatg attcgtcgtt ttcgtcagtg
     1681 ggcacatgaa ggagacaatg agtccttctt caaaaaagcc aaagaactgg aacgccgcct
     1741 ggcgaaactg acactcgtca aaccgccacc tcccccgaaa aatcggctgc aaagcttgtc
     1801 taatggtgga aaatctggca aagaagtttt catcattcaa aacttgcacc agcagtacgc
     1861 tgatcaagta ctattcaaag acagcagttt tgcagtctat cgtggagatc atttagccat
     1921 catcggcgac aatggtgcag gaaaatcaac cttactcaaa ttattactcg gtgaggaaaa
     1981 gccttacggt ggcaccatca aattaggtag tagcttgcaa atcggttatt tgccgcagca
     2041 gctgcagttt gccgatcccg atagccgttt gctggcttac gccatcacat tgactggaaa
     2101 cgaagaagtc gctcgacggc aattagccaa aagtggcttt tatcaaagcg atgtgggtaa
     2161 acggatcaaa gatttatccg gtggtgaaaa aatccgtttg gcgttgctga aactcttttt
     2221 agaaaaaatc aacgtcctga ttttggatga accaaccaat cacctcgaca gctatgctcg
     2281 agaagaaatt gaagaaatgc tgcaagacta tcaaggaacg ctcctagcag tcagccatga
     2341 ccgctacttt ttgcagcaac acttccaaga agcactcgtt attgatcagg agcagatcag
     2401 ccgccagccg ctcggccaac tgattgacta ggacgttttt tcgcaacaaa aaacttgatt
     2461 ttcatacctg tgctttcacg attcaggcaa agtacaggtg gaaaatcaag tttttattat
     2521 tcgatcaatg aatgtttcgg atcggttttc tagctaaaca taaagcgaag aataaagtcg
     2581 acagcccacg aggctgatct aaaaatgttt tttcttttta catatgtaat gtcccttata
     2641 aagatgaatg aaaataaaat attgggattt tcctgaaaat caataaataa aatgccagtc
     2701 ttttcccttt tgaccacttt tccaagcaaa attccctaag aagatcctgt aaaaaagaag
     2761 ggaaattgaa gttaaattac cattttgcgg tcttctccgc aaaaaaaaca catgcaagaa
     2821 ttccctcttg catgcgtttc atcttttatc ctaacgaatg ctttggctta gccgcgcaga
     2881 cgctccacat cacgggcaat cattagttcc tcatctgttg ggatcactaa tactcttact
     2941 tttgattctt ttgtagagat atctacttct tcaccacgca attcattcaa cgctggatcg
     3001 atttcacaac caaaccaaga catacctttg atgatttcac tacgtacatg tccgtcattc
     3061 tcgccgatac cagcagtaaa gacaattgca tcaacaccat tcatcgttgt cacataaccg
     3121 ccgatgtatt ttcggatgcg gtccacgaaa atgtcataag ctaaacgaat atgttctttt
     3181 tcatagttct tttcaagatc acgcatatca ctagacaatc ctgttaggcc tagcagacca
     3241 gatttcttgt tcaaaacatt gatcatttca tcaatatcaa tctctaattt ttccattaaa
     3301 tatgggagaa cagctggatc gatatcacct gaacgtgtac ccattgtcac cccagctaat
     3361 ggtgtgaatc ccatagaagt atccatggat ttacctccat cgactgctgt gatcgataca
     3421 ccatttccta agtggcaagt gatgattttt agttcttcga tcggtttgtt caataatttt
     3481 gccgcacgtt ccgacacata acgatgactt gtgccatgga agccatattt tcttactttg
     3541 aaatcttcat aataagacac cggtaagcta tataaataat tttgctttgg cattgttgag
     3601 tggaaagatg tatcgaatac agccacactc aaaatgtcag gtaaaatctt tttaaacgct
     3661 ttgatcccca ttaagtttgc aggattatgc aaaggagcaa attctgctaa ttcagcaatg
     3721 cggtccatta ctttctcatc gatcactact gaatccccat aagtttctcc tccgtgaaca
     3781 acacggtgcc ctactccggt gatttcatca taagagctta aaatttgcag ttcaatcaac
     3841 tgatctaaca gcatttttac tgctacttcg tggttttcga tatccatgat ttgttcgaat
     3901 ttttgattat cgccgtactt gatggtaaaa atagaatctt gtaaaccgat acgttcgacg
     3961 atccctttcg caactacggt ttcttctggc atttgatata attgccattt caaacttgaa
     4021 ctcccagcat tgattgcaat tgttttagac atatgactct ccttctcgtt gaatgattac
     4081 agagcagatg atttccagtt tttaaactcg ttgaaaaatt ccgtcacctt ctctggttct
     4141 tttaatgaag caagtttcac aagcaagact tcttttactt gttgtgcttg tggtcctttt
     4201 ttctgtaaga tcaaaatact tttttgcgat tgtttattac ggaacaattc atctggcaat
     4261 tgaatcattc cttgaagata accttcttct ttaaaccatt ttttgatttc ttcactttga
     4321 tccgtttcta aaaatccact cggcatcaaa aacaaaccaa aaccatccgg cttcacatat
     4381 ttcattgatt gctctagcaa taaatgatgt gcataactat ggccttcttc ggtacttgtt
     4441 aaaaactctt ttgctttttc gtcattcgga taataaccga ttggcaaatc gctgattgca
     4501 aaatcgacag gatctattaa taattcctgc aacccgtctt gatgaaagta ttgaacattt
     4561 gcttgtgtca aatcacttgt agaagctgcg acagccaaca atgtatcatc aatatccaca
     4621 ccaattcctt ctgtttggta ccccgcattc gataggttta aaagaactgt taataacaag
     4681 ttgcccattc ctgccgcaat atccagaatc ttaaccggtg cttttttatt tgtgtatagt
     4741 tgttcaataa gaaaaacaaa taaaaaaccg atactatcag gagtgagttg atggttcgcc
     4801 tgcaaatgtt ctgtctggct gcccttcaat aaaagtaatt gagacagtct gcgccattct
     4861 tctggctcga aagaaagttt cttcaactct tcataaagag ctgtgatccg ttgcgttgtc
     4921 tcttttgtcg gcactccatc caccacacgt acttgataat catctattaa attttctgca
     4981 ttttcgacat aggcttctaa aaaggaagtt cccaatgcat tctgtaaaag ctgaatagct
     5041 tccaggtttt gattaaaccc ttgttccatt ttttctggta acatggtgca cctcatttct
     5101 agatatatta taacaatttt ttcacctgtt taattctatc gaacaattga caaaatttca
     5161 atcgttttca ctgtttttta tttgtgaaac ggcaaacatt tttttattaa aaacagtgtt
     5221 ataacagaaa agagggcgtt ttcacgaaca ttccatcatt ctgtactagt atctgtatca
     5281 ttttttactt cttctgtgaa ccgaaagata aacggtgaga cttccacctc taagaatagg
     5341 gactgttgta cccactgata tgttacagat ccagttgtgt agtaaaaaac tccttccgaa
     5401 ctttcggcaa gcgtagactg ttccgataaa gccatctgct tcattatttt tgctatataa
     5461 taatttttga ttcgtatatt aagatccatt gacaaacggt agctttctaa tgctgccatc
     5521 aataaaaacg tacataaaag aaataaaagc aagacagaaa ataaaataga gcccttataa
     5581 cattttctac tgatcgtttt ttgtccatat ggcatatcca tcttctccat tttcaaagtg
     5641 tacataaaaa gaaattgtgt gttctttttc caataattga agctcagtga tacttgttaa
     5701 cataggttga tgtccgccgg aagttcttct tttacgtatc attgcctgat atctttcgat
     5761 gatatactgt ttatcctcga tcgtgtagtg cagttgctga tttttcacag agacattgtg
     5821 actgctcttg agttcttctt ctaattgtgc taaaaatatt agccactctt tttgatcttt
     5881 acgctgcaaa aattcactta cttggatggt ttgctgaatc aaaagattga atgtgagcaa
     5941 tagactgctc aatatcatca gtccaattag acattcaatc agcgtaaatg ctggaattac
     6001 ttgttttttc aatactgatc gcttctttct ccatattgac aaacactttt tcgattactc
     6061 cattattatc gacaatttgg atatcgtatg ggatcatttc ttcccttcgc tctggtcttt
     6121 tgtgatacat ccgctgcgtc ttgatatctt cataaatcat tcgaataaat agcagttcct
     6181 ccccactttt cttttctgcc tgaagcaaaa acagctggcc aaagctcact aagtagacac
     6241 agacagaagc gatcataagc gctgtaaggg actccaacaa aacaaatcct gttttattca
     6301 attctttttg tatagcgacc actccctatc tggaattgat acgtaatcgt ccgctctttt
     6361 tcttcccaat aaaattgata agcttttagt gaactttcat tcccggttct agcagcaaaa
     6421 gtaatagaag catggcgttt caaggtaatc tcatcaggaa tatctaatac ttcccaattt
     6481 attttatctg gattcggaac atgaaaaatg atttgattct cttcactatt ccaataaaag
     6541 cctgtttgga tctgattcac aatagcgatt ttttgcgtag aatagattcg tttttcaaat
     6601 tggccgaaaa attgatagac tgccaattca ttcttccatg cagaaaatgc gagaactgga
     6661 aaagaaagga tcgttgtaag taataaaatc agtaagagtg attcaaacaa cgtatatcct
     6721 gatgctaaaa ccttaccttc aaggccgctg atagatttct gcatgttctc gtttgatata
     6781 gccttcattc aacaattcct ccacagtagg aactcttcca ttattttgaa gcgcatagag
     6841 ctctttttgt gtgtctacca actggatgat cgcttcacga ctttcttggt ctacatgatt
     6901 cctataacgc gacaaattag ggacgaacaa caacactaat acactgatga tcagtaagac
     6961 gattagcatt tcgatcaatg taaaaccgct ataataagat atttttctct ttttcatggc
     7021 aaaacctcct ctatgcttcc gtaaacaggt aataaaacag cggcataaac taataaaatc
     7081 aaagccgcta cgcccaaaaa aatgattggc tgaataaaat gcatccagtg atgaagacgt
     7141 ttgaaaagct gttttcttgt ccattcgctg taaaaaatca gttctttacc taaacttccc
     7201 tttgcctctc cctgtaaaac aattttactg aattcttctg atagaaaacg ataattctgg
     7261 aactgctcag ccaatgacat acctgcctcc aatccttgaa tcaacttaga ggcaagatgc
     7321 tgaatcagac tttcttgttt cgtttccttt aagcagacta tgatttgcct taattcgaaa
     7381 ccttcatgaa aaagctttcc aatctctagt gacaaataag ccgattgata caaggaatat
     7441 atcggtccaa tcaataattg tctgcttatc cattcactct gatcaacagg agacaacttc
     7501 atcagacgat accttactag taaagccaat agagtaaccg ctaggatgaa tagtagaaca
     7561 taccaatgaa agacttgtat cagctgaata ccccaatgct cttgcatgac cattcctgaa
     7621 ccaataagct gaggcaaaac gaacaaccgc atactaaaca agatacctag caaaaaggtg
     7681 agcaatagca tcggatatgc aagcagcttt ttcaaatcat tgcgaaatcc ttcaacaagc
     7741 cgaaactgtt tggcaatttc caacaaagtt gtcggcagat tcccatgacg ttcagctaac
     7801 tcgatctgta ccagttgctc tgctccatat cctatttgcg aaagtacctc actaaacgct
     7861 tgcccttcct ttagctgatg ttggatattt gccaaaataa caggtggaaa cgaacggatc
     7921 gtgagtaata aataaaggga ttcttgcaga ctaaaaccag ataaaagcag ttctcccatg
     7981 gtttgtgcaa actggttttg ctggcttctt gttaatcctt tagaatagtt ctgactgcca
     8041 aatattttcc tgagcttctt cataactttc ctcccatgat ttttttactg attcttcctc
     8101 cataaattga taactccata aaacagaagg atggtgattg gcatcttcca aaagttcttg
     8161 ataaatgaca ccagctaaac attcagatag ctcttctttt ttctttgtca gttcatggat
     8221 tctgaccaat gtaccttcaa gattgcgtgc atgtacggtt gcaaaaaccc ggtgccctgt
     8281 tagtgctgct cttaccgcag catgtgcagt tgattcatct cttatctcgc caatgattag
     8341 caagtctgga cgatgccgta atgcgagtct caaaagtgta tcataagtct gtgctatttt
     8401 cggattgatc tgtagctgca gaaaaaacgg ttcttctatc tctacaggat cttcgatagt
     8461 aatcacttgc aatttttctt ccaaagccaa ccgatacatt agagaagtct tgcctgatcc
     8521 gactggtccg ctgaaaaggt ataatccacg tctgacggtt ttctgtaaaa tagttgcaaa
     8581 atctcgagaa ctaaagcaac gatggggtgt ttcaaaagta ccgtataata gccgaatcac
     8641 taaactctct cgttgaaggt aatctcctac agaagacaac cgcagacgaa cttcctgttt
     8701 ttctaaagaa taagtaaatg cacctaactg agcttttctt ttttctccga tatccatctg
     8761 tcccaaatac ttaaatcttg agatcagttg ctgtccatct gccgaagaga ctttcttcca
     8821 gaatgttcgt ttttttccat agcgaaaata gatgtaaaat acttctgaag ctggcaatat
     8881 atatacgtct tgggcatgtt tggcaaaact ttcacttatc atttgatccg ataatcgttt
     8941 tatttccatt attctcccct ccacaaaaaa catacgtctt tttgatcttt ttgtttcaaa
     9001 taaaatgaat ttacaaaaaa atattggcaa aaaccgaatt tatgttatac ttataaaaat
     9061 ttatcttggg aggcactcca ttggaaacaa cattaaggaa atatatcgaa gtagcaagta
     9121 aaaaaaagcc tgctgaccta gtgatcaagc atgctaagat cgtcaacgtc tttacgaaag
     9181 aaatcatgga aaaagatgta gcaatctgcg aaggaatgat cgtaggaatc ggtgaatacg
     9241 aaggaaaaag cgtacataat gctaatgggc aatatctagt gccaggattc atcgatggcc
     9301 atgtgcatat cgaaagctca cttttatcac caagcgaatt ttcaaaagta tccttgcttc
     9361 atggagttac tactgtagtg acagatcccc atgaaatagg aaacattgct gggagtacag
     9421 gtcttgagtt tatgatagaa gatgcaagac aaacactcat gaatatcttt tttatgctac
     9481 cttcttgtgt acctgtaacc ccttttgaga ccaatggtgc aaatttaaat gcaaaaaaat
     9541 tagccccttt tttacaaaaa cccgaagttt taggcttagc tgaagtcatg aactatcaag
     9601 cagtagcaaa taatgaaaca gacatcctag aaaagatcca attgatgcac cagcataaga
     9661 aaaaaattga cgggcatgca gctggtatcg gcatggaaga gttaaatgtt tatcctgcag
     9721 caggtattcg gacggatcat gaagctacaa ctgcaaaaga agctaaagaa cgtttggatc
     9781 ttggtatgta tttaatggtt cgagaaggga ccgttgcaaa agatctggca tcgctactac
     9841 cggcgatcac acctgaaaat tcaagaagat gcttctttgt caccgatgat aaactgatca
     9901 atgatttagt aaaagaagga tcaatcgatc atatcgtccg tcaagctatt gcacttggaa
     9961 tcgatccatt acaagccatt cagatggcaa cattgaatgc agcagaatgt tttgatttga
    10021 aaacactagg tgcgattgcc cctgggtatc aagctgattt cttcttaaca gacgatctta
    10081 ccaagctgcc aattcatgaa gttttctata agggaacatt agttgttcaa tctgggcaac
    10141 tccaagacca tttatttgct gatcattcaa attcatatac gtgttgtctg ccaaaactaa
    10201 acgctcaacc attaaatcca cattcgttag agctgcttct ttcttcttca caagcccatg
    10261 tgatcgaaat tatcccgaat agtctagtga ctaaagattt ggtagaaaaa gtggaccgac
    10321 aaggcgaacg attcattcct tcaatcgaaa aagaccaatt aaagattgcg gtgatcgagc
    10381 gtcaccatca aacgggaaac attggattag gcatagtgaa aggatttcag ctgaaacaag
    10441 gagcgatagc gacaacgatt gcccatgact cgcataatct agttgtcgtt gggacaaacg
    10501 acgaggatat gctgtatgct gctaatcttt tgattcaaaa aggtggcggg atgaccgttg
    10561 tcaacaatca gcaggaaata gcttgtgttt ctcttcctat aggcggaatc atgacacagg
    10621 aacctttttc gatcgtctat gaacagttga atgaattaat aactaaagca catcaactag
    10681 gagcagctaa aacctttgat ccttttttga cactttcttt cttaacatta tctgtcatac
    10741 ccgaattgaa gatcaccgac aaaggattat tttcattttc tcgcttccaa ttgattccac
    10801 cttgtggaaa aaccgatgaa ataaatacat tttaaatcaa ataaatccca gaaaatacat
    10861 tacatctgta atgttcattt tctgggattt atttatggat attaatgttt ttatgaaagc
    10921 agaaagttag tttcacagac ttttcttttt ggtcttatct tgaaattgag cttctactcg
    10981 ataaatacgt tgaccttttg aagaaaattt ttcttcatac tccgtcataa tattgccttc
    11041 aaattgactt tgatgtaaat ctaaccatac ctgtttgagg atcatgccat attgagaaaa
    11101 acttgccaga gaatactcaa acaatccttg attatctgtt ttgaaatgga tttctccatt
    11161 tggacgaaga atctgttcat ctacagcaag aaaagtctta tatgtcaatc gccgtttttc
    11221 atgacgtttt tttggccatg gatcggaaaa attcagatag atttgatcta cttcgctgtc
    11281 agcgaaatac tctgtcaacg ctgatccatc cacatgtaga agtttcaggt taggaagcgg
    11341 ttgttcgatc aacttgtcta gtgcaatcga aacaacactg acctgcattt ctactccaat
    11401 ataattgatt tcaggatggg cttttgccat tccagtgatg aactggcctt tccccatacc
    11461 aatctcaatg tggattggat gatcgttttc aaacaattca ttccattttc ccttccacaa
    11521 tgttggatca ctaattacaa aattcgggtg agccgctaac atttccgctg ctcccggacg
    11581 atttcggaca cgcattattt atctccattc ctttcctcta attaaaaagg tctggccaaa
    11641 tctccgcaga gtttgggcca aacctcagcc actgaaaatt cgttttaatt gtaaaatttc
    11701 ttcgttcatc cgtcgatgat cttcacgttt gcaatatctg gtgatttctt ggagcaaatt
    11761 catggccgca taccaatgaa atttttcaag catttcgtca gtcgggcgta tgccataact
    11821 gatcagccac tgattccagc tagacagtgg cacataattt cctaaaatcg ttgcaatatc
    11881 caccgcaggg tctgcaaaca tgattgaatc ccaatcgact agatataaat aatttttaca
    11941 tactaaccaa ttacgatggt ttacatctcc gtgtactact gataagtttt ccttatctat
    12001 tgacgggatc tgctcacgaa gaaaacgatg gacaatttgc agaaattgat ttttctggag
    12061 ttcttccggt aattcttttt catatttttg cagcatcttc tccggcgtca tgacacgacc
    12121 accgatacgg gtcagcatgg ttttaagaga atttgaatga tgtaaatggt acaaaacatc
    12181 aatcacgtcg tttctttgac caatctcatt aggagtcagc aagcgacctt ccagccactc
    12241 ttgtgctgtc aaagtatcgc cattccccgt tcgttttgtc caaacaagtt ttggtgtaat
    12301 tccttccctt gaaagagcag ccaacatcgg agtcgtgttt cgtttaataa agactttgtc
    12361 ctcatcacgc atgcctatgt atgtttttcc tgtgtcgcct ttgatgggac gtaaccgcca
    12421 ctcttggtct aactgaaact ccatcatgca ttctcccgtc ctcttactct ttgttttgca
    12481 gtacttatta ttctagtcgc ctgaacacta cacgtcaagc acatatacgt tctttttcat
    12541 ttaattgcca ttcaaaaaac cagcttttct caaaaaaaat agaacgaaca gcattcttac
    12601 tgtcaacgct ctatttttca ttctcatttt taccctacac agctttgttt tcagtctgac
    12661 atcttcttca aacgagttgg tacatatagt ttaacaaaga gcatagtaac aatcaaataa
    12721 gccgctagcg gaacccatcg ctgctgccca tctaatacga ctgcagcaat caaaccaaaa
    12781 ataaccgacg cgataattaa tacccatgtg agtagatact gaatcgcctg cttcttctga
    12841 ttcttatgga ttggataaag ctgaacgaga accatatagc ggaactggtt cgctaaaggt
    12901 aacagttgga aaccgatcaa atataaaaat aagaaaccga taatcagact aaaataaaag
    12961 tcgactactc cggcaatcaa taacccacct ataattacta atcggaaata aagaccacta
    13021 aaatcagaac ctcttgccaa tcttcttgca aacaagtaaa gataagtgtt ttttgattct
    13081 cttttaatat gagtcaatat aggatccaaa tagcgtcttc ttttgatctt tgccgtaatt
    13141 tcaggaacat ctgtgaataa attgataaat tgatagatct gatgcaacct atgttcttct
    13201 acatgcacca ttttctccca atccaatcct ttttcttgtt gcttccacaa aaaccagtaa
    13261 tatagacttg cctgtactaa tgcacctgct attcctgccc atattagcca ataaaatgat
    13321 agaaacaaaa agatcagaga agaaaaaaac cagcctaatt tccaataacg aataacttgt
    13381 tgatctagtc gaaacaattc tgctctcttg atttgcagat gactgaattt caaactccat
    13441 aatatgatca gatagacgaa aaacatcgaa aaggattgct ccgtactaac caccactaat
    13501 ggcatggcca atccgcatgc caatatcaaa aagatcaacg gaaaaatgca agaatagcga
    13561 aaagctcgtt ccaaataggt ttgcatttct ttttctttag gaagtaaaaa aacaatatct
    13621 gctgcctctg caaaagtagc catcttaccc acgaataaac agagcatcca aaatacagag
    13681 attatgagcc ctccaattgc aaacggtggc tgcagggttt tcaaccaatt agaataatat
    13741 aatcccacac cgccaatcaa gaaaagacaa actaaaacaa aatgatcgtt caatacataa
    13801 cgcatatatt tcatcatttt cttttgatgt cttgctaaac gtttttgaaa aaaactactc
    13861 atgtgcctgc tcctttgtta aagcaatata gatttcgtcc aaagaagaat ccggcagctg
    13921 aaattctttt ctcaacatct caagagaacc gtctgctcgt atctctccgt tatgtaagac
    13981 cacaaaacga tcacaatatt tttctgcagt agctaaaata tgcgtagaca tcaaaatacc
    14041 ggctccttct tttttcattt ctaccatcaa ttcaagcaat gcattgatag ctagtggatc
    14101 caagcctaaa aatggttcgt cgatgatata taaagaaggc tcgatcaaaa aggcgcataa
    14161 gatcatcact ttctgtttca ttccctttga aaaattagct gggaaccagt caagacgatt
    14221 agataaccga aaagtctcca acaacttttc tgctcttttc attgctatat ccataggtat
    14281 atcgtaggcc atcgcagtga cttcgatatg ttctctcaat gtcaattctt catataaaga
    14341 aggagtctct ggaatatacc caatttgttt gcgatattct tccgtatttt tctttaagga
    14401 tagatgattg atttctatcg ttccttttga agcttccagc agaccgataa tgtgcttgat
    14461 ggtcgtactt ttccctgctc cgttcagtcc aatcaaccct actatctctc caggctgtac
    14521 atcgaaactg atatctttta acacagggag atgtccgtac ccccctgtga catgatcgat
    14581 aattaaactc attctttttc ctccgccatt tatttttatt tattatacca cgaagaaaat
    14641 gacggtattt tgtttttttc cttacaatag ctttaactta tggtaaagtt aagctgaagt
    14701 atttattctt tatagaaagg atgttttata tggaaaactg tattttttgc aaaatcatca
    14761 atcaagaaat cccaagctat aaaatatatg aagacgacaa ggtctatgct tttttagaca
    14821 tctctcaagc aacgaaagga cacacattag ttgtgcctaa acgtcatgta gcagatattt
    14881 ttgaatatga tcccgaactt gcaggagagg ttttttcgcg tgtgcctaag attgctcaag
    14941 cattggaaaa agcttttcca gaaatgaaag gtcttaatat cttgaataac aaccgtgaac
    15001 tagcctatca atctgttttt cattcacata tccatttagt ccctcgctac agcaaagagg
    15061 atgatttttc tattcacttt gtcaatcatc aagatagtta tggatcggaa gaactaaaag
    15121 ctattcaaga aacaatcgta aagcaggtgt cctgcgatga ttaaaaactt tttcaaagga
    15181 ctgttatttg gagctgctgc tggcactgtc ggaggtctgt tattggcgcc caggagcggg
    15241 aatgaaacaa gaaagaaact gatcgaagaa ttggaagaag caacaactct gacaaatgat
    15301 ttaaataaca gcctgaatca ttttaaaagc gcattgatcg aaacaaaaga aacagctgaa
    15361 tctgtgattc ctgctttcca agaagcaatc aaaaaagata tcgaagattt taaattccaa
    15421 gccgaaccac gtatcacaca aatcaatgaa caagtagaaa aactaaaagc tgatctgcca
    15481 gagtatcctg aacaaatata ataatgatta ttttctcaac agatttaact atataagtga
    15541 gaaaagtttg cgtatttcct aggaatgtga tgaaattttg aattttgttt gaaactacca
    15601 cgacaacgtt tttaaaggaa atgggatatg gtatagttaa tatataaaaa taataactaa
    15661 ttacaggagt gcaaatttta atgaaaaaaa aatcaattat tttggcagct actagtgcgt
    15721 tggctgtttt aactctagca gcttgttcag gcgatactaa taaagatatc gcaacgatga
    15781 aaggcggaac gatcactgta tctgatttct atgatgaagc aaaacttgaa tcatcgaacc
    15841 aatccttagt acaacggatg atcatttata aagtattcaa taacaaatat ggcgataaag
    15901 taaccgataa gcaagtggat gcagaatacg acaaacaagc gaaatcatta ggtgatactt
    15961 ttgaatcaca attagaagct gctggatata cgaaagatac ttataaagaa tatattcgta
    16021 acaatttagc ttttgaagct ggcttgaaag ctcacgtaga tattacagat gacgatttga
    16081 aaactgcttg gaaatctttc catccagaag tagaagcaca aatcatcaaa ttatcaagtg
    16141 aagatgaagc aaaagatgtg aaaaaatcag cggatgatgg agatgatttc tctaaattag
    16201 ccaaagacaa atcaactgat acagagacaa aagaagatgg cggtaaagtt aaattcgact
    16261 caacgacaac aactattcct gcagaagtaa aagaagcagc tttcaaattg aaagacggtg
    16321 agatctccga tgttattact acaacaaatc ctacttctta tgcgacagaa tactacgttg
    16381 tcaaaatggt gaaaaaccaa aataaaggca atgacatgga taaatacaaa gatcaactaa
    16441 aagatatcgc tactgaaact aaactaagtg acaatgcatt cacaactaaa gtaatcggtg
    16501 aagaattaaa agatgcaaat gtaaaaatca aagatgatgc ctttgaaaat gtgttgagtg
    16561 cattcacaac aacttcatca agtacgaaag actcaagtga aactacagct tcaacaaaga
    16621 gttctgacac aaaatcaact gattcaacaa aagaatcttc aactgaagaa acaactgatt
    16681 catcaaaata aa
//
LOCUS       DADVXE010000056        16392 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.057, whole genome shotgun sequence.
ACCESSION   DADVXE010000056 DADVXE010000000
VERSION     DADVXE010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.057"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(51..1598)
                     /locus_tag="KB913_002078"
     CDS             complement(51..1598)
                     /locus_tag="KB913_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBB6820420.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="KB913_002079"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="KB913_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBB6820421.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="KB913_002080"
     CDS             complement(2043..2237)
                     /locus_tag="KB913_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820422.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            complement(2463..3665)
                     /locus_tag="KB913_002081"
     CDS             complement(2463..3665)
                     /locus_tag="KB913_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6820423.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(3668..3862)
                     /locus_tag="KB913_002082"
     CDS             complement(3668..3862)
                     /locus_tag="KB913_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBB6820424.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(3909..4757)
                     /locus_tag="KB913_002083"
     CDS             complement(3909..4757)
                     /locus_tag="KB913_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HBB6820425.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(4962..5312)
                     /locus_tag="KB913_002084"
     CDS             complement(4962..5312)
                     /locus_tag="KB913_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820426.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            5907..6353
                     /locus_tag="KB913_002085"
     CDS             5907..6353
                     /locus_tag="KB913_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBB6820427.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            6977..7969
                     /locus_tag="KB913_002086"
     CDS             6977..7969
                     /locus_tag="KB913_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6820428.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            7985..8869
                     /locus_tag="KB913_002087"
     CDS             7985..8869
                     /locus_tag="KB913_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6820429.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            8918..10525
                     /locus_tag="KB913_002088"
     CDS             8918..10525
                     /locus_tag="KB913_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6820430.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            10526..12010
                     /locus_tag="KB913_002089"
     CDS             10526..12010
                     /locus_tag="KB913_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HBB6820431.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            12187..13179
                     /locus_tag="KB913_002090"
     CDS             12187..13179
                     /locus_tag="KB913_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6820432.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            13231..14100
                     /locus_tag="KB913_002091"
     CDS             13231..14100
                     /locus_tag="KB913_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6820433.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(14520..16085)
                     /gene="guaA"
                     /locus_tag="KB913_002092"
     CDS             complement(14520..16085)
                     /gene="guaA"
                     /locus_tag="KB913_002092"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBB6820434.1"
                     /translation="MSSPTRFDEEPKIIVLDYGSQYNQLITRRIREFGVFSELMSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGK
                     VKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCP
                     IASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGK
                     FGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(16140..>16392)
                     /locus_tag="KB913_002093"
     CDS             complement(16140..>16392)
                     /locus_tag="KB913_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6820435.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVSHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         4956 a         2866 c         3325 g         5245 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga aaacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agtaaggtac tgttctatgg ggcgcttacg ttgaaaaacg ttgatttatc
     2341 ggcattcccc atccatatta tatttacgtc ttattcccac tcaatatgag tagcctcgta
     2401 aagaagctat tatatcagtg ctttttcagc ctattcctca ttttggtagg gaaatggtag
     2461 ggttagattt ttactgcttg atttccatta aagtttgcaa ctttagattt tgttgcacag
     2521 gtaaatttaa tgtttcctgt catttgttct gcaattcctt catcattacg gctccataga
     2581 tgagcgtagt gctttaaagt gatttcaggg ctagaatggc ctaaccgttg cgacacgacc
     2641 agaatgtctg cgttaaactc attgattagg tagctaacat gagaatgacg taatcctttt
     2701 ccttgtatta ggggtacctt agctagtttg gcataacgct gaataattcg ttgaacagtt
     2761 gaacgataga gtgggaggtc agtgtagcta agaataaatt gttctacacc atgatttttt
     2821 tgaataactt tccacttttt tagcacttca attgtatcat cgtccagaga aatgatccgc
     2881 aagccgcttt cagtttttgt gtaaggtttc cgaataaaat ctttttgatt tgtcatttcc
     2941 aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca cgtcattcca attaagtgct
     3001 aatccttcgc ttacacgaac accagtcatg taatatagcc agatcattaa aaaacacata
     3061 tgttcgtaga aatcatcttt ataaattttt gccaaaactt cttcaaattc ttcttttgtc
     3121 cagtaaggaa cgattgattt tccttttgga attgcttttg ttcttttgga aatattctca
     3181 ttcagaaatt gcagggtgac cgcatagtct aatgatttac gaaacatacc gtacataagt
     3241 gaactgtatg cttgtgagta tccgctatcg ttcaataacc aaattcgata attttcacaa
     3301 tctcgcacat tgatttcacg aagcttctta tcaccgaaaa attcagtaat ctgaatcaat
     3361 ccacactcac gagaactcca agtacttttt tgtacgctag ctttgtagtg tggaacgtaa
     3421 gactgctcca taaattcttt gtaagttaaa tcataattcg caaatccatt tacaaccatg
     3481 tattcatttt ttatacgcat gacttctttg tgtgcttcac gagctgatga gaatcgtttt
     3541 cctagagaat cttttgttcc tttcttctgg atcctctttc cagtcacttg atctgttcct
     3601 aactcaacta gataagaaaa gcgaccattt ttatcttgat acacacaagg gtattttgtt
     3661 ttcatagtta ttcctcctgt gaaagaggaa cacctataat ttcttcaatt acttgtcggg
     3721 gtactacccc aactctttta ttattataat atggatatcc ctgatttacc attcttgttt
     3781 ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa tcctagagcc tctaaatctt
     3841 ttcgacaaat tgtatttttc attgtataaa ctcactttca aagaaaacac tatcattggg
     3901 taatagtgtt atttctttat ttttgtataa tgaacggtac tttcttgaaa atccatcact
     3961 tgttcaggac ttcccaactc atttaaagct aaagcattgt aaaaaaatgg acgtctaact
     4021 atatattcgc ttgtatatag tatatcttga ttcgtggaat catagggttt ctttaccatc
     4081 tttttggtga cagttggtag tttgagattc cgggacttga aaaaagcttt tttcttatgc
     4141 tctttcaatt ccagctcttt atcgaaatat ttgctgatat agcgcccgcg attttcgata
     4201 ctgtctacat cgatcttgtt gatcttaacg aaaccctgac cccaaatcgt agttaaccgg
     4261 ttaaatgaga taaaggggaa atcaaacaag ataatatggt agtggattgc accgcgttgc
     4321 tgcttttccc acgtggcgag atactttaaa tttgcttttt tagttttata gaggtcataa
     4381 ttcagtcgtt tgataaattt tttaaattca ttatttgcat actcaatgtc ttgaatgttt
     4441 tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa aattcgtgtc tacaaggcgg
     4501 gcaatctcaa atcgcatact ttgataatgt ttctgtttgc gttttaaact gtcatattgt
     4561 ccttgagcgg ataattcatc atagtttttt cttttttcaa gagtaatatc attttcataa
     4621 atccaagcta atttttgttt tcgttccaga tttacttcgt tttcgatcgt tttacgtttg
     4681 ggagtaatga ttgcttcata atcataaatt tcaatatacg tgggagtttc aatgattttc
     4741 tgattataag cttgcaaaaa tcatcactcc ttgttgcgta ttcgattgtc aaagaaccag
     4801 tcattttctc ctgatgttga tctataaatc aagttaaggg ggaaggcctg cgtagcagcc
     4861 cttctagcct atggggtgtt gggcggtctt aacggacaga aacggctctg tgggcgctgc
     4921 cccgccgttt cgtcctaacc acccaacact ccatagtata gttagttttg tgtagtggta
     4981 ccttgttttc tgggaatcaa agttgccgta tcagcggttg ccgataaccc ataactgaca
     5041 aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat tggtaaatgt aattatggct
     5101 aaaccttgtt gggtaagttc ttccggcgtg atcacaggat gttcagattt gactttgaca
     5161 ctgatttttt cgtagcgaag ttttggtagg atacattcgt agctccaacc tagaatttcg
     5221 ccctcctttt gccagcgagt gacattgacg acttggtatt ctttttcgag tgtttctttt
     5281 ggtaaactga gatcggtaat ttttattggc atcacaattc tcctttttta tacgaaagtt
     5341 tatacgattt gattaaaaaa tatagatggc catctacgac ttgtattata tacgagaact
     5401 tatacgtagt caagagattt tctaaaaaaa tatatacgat tttttatacg agtgttataa
     5461 tgaaaaaaat gataaggagg aatttgaata tgtttggttt agtacaacct aataaagtga
     5521 aggtgggcca acgaatcaaa gaaataaaag acggaatgtc tctctctttt acagaattag
     5581 ggaatcgatt aggtttaaaa aagccgacga tcagttccta cgttcaaggc tatgcgttgg
     5641 ctcctaagag tgtgatcaac caattatcta gtatcagcgg aaaacctgtc ggctggtttt
     5701 attttgggca tgtggaagaa tatatccgag agtatttgtt tctcattggt cagaaaaaaa
     5761 tagtggacga ttatcctgaa atcattgaga aaataaagca agaattttat acgggcgagt
     5821 tcaaaaatcc tgcttgggag aatgagctag gctatccttt ggaggaattt atccaagaat
     5881 gttttgtaga atattcgagt gaaatcatga aggactatgt cgtacagatt acgaaagagg
     5941 tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa agcaaaagaa gaagctgtca
     6001 cgattctttc atctgggatc attgactata tcgagatgag tggtgagatc aagtatggag
     6061 agaaagatcg cattgcgaaa atggtgaaag aatcaataaa aacctttgat gtgaaacaag
     6121 acctgacatt taatgattcc tatttgattg gaaagttgat caatattctt ggtacagatg
     6181 aagatacgga gctgtttctt tcttctttat caatgatatt tactgataag catttttcca
     6241 ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc gatgcgacca gcgttaatca
     6301 aactctatcg ggagaaaaca ccagatgaat tttatgattg gtttgagaag taaaataaga
     6361 aaagtggctt agattacaag ttggtgaaaa aatttttttc agcataacat cagtaatcta
     6421 taaaggggtt gttgattata ctgtagaagt taagtactca agagattttt tgtacgtaaa
     6481 caaagcaaaa aagggtgcag tttcactaga aaatgtactc ttttttgtga tttttcttag
     6541 ttatagagtt tttttgaaac tttaaaaatg agaaaacata ttgattttaa agagtgtaga
     6601 catagcttct tttgctaaat agattaaact tactggtgag tggtcttgaa catactttta
     6661 aatcacattt tactgagttt tattggattt tataattcat tggaaacctc gtacttaatc
     6721 tgtttttatc tatcgactag aatctgtata tattccagct atcaatgagg ccgcagaaaa
     6781 gggtgcttaa aaataatctg ttgtttaaaa tattattatc agaatactta gatacaaaat
     6841 tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg atatggtaat ctataaacga
     6901 aaatagtggt aacgtttcca aaatgcatct tcgttaaatt tttatttttt taaacgaaaa
     6961 tggaaacgtt tctaaaatgt attgggagga gattgaattg gaaaagacat tgggaccagg
     7021 tggtgagata agggcggtac aacgggataa aaaaaatatt tcgaagtggg aaaaattaaa
     7081 gaaacagttg cggcgtgata agtggatgta cttgttgctc ttaccaggta tcatcatgac
     7141 gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt gcatttaaag actataatcc
     7201 tatgctagga attttggaaa gtccttgggt aggactagat cactttaggg aatttatcag
     7261 ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa attagtattt atggtttatt
     7321 gttaggtttt tttccaccaa ttattttagc actgagcttg aatcaaatta tcaataaaaa
     7381 aataaaacag aaaatccagt tgattctata tgcgccgaat tttatctcag tagttattat
     7441 tgtggggatg ctgtttttgt tcctatccgc aaatggacct attaatgggt tagtagaaaa
     7501 ggttacgggg caaccaatta tgttcatgtc taatccagct tatttcagaa cgatttatat
     7561 tttatcggga atttggcaag gaatcggctg gtcatccatt ctttacaccg caacgctggc
     7621 gggagtcagt accgatttat atgaggcagc aaatatcgat ggggcaaata ttttacaaaa
     7681 gatttggcat atcgatttgc ctgcattgag gcctgtgatg gtgatcagct tcatcttggc
     7741 cgccggcggt attatgaatg taggatatga aaaagcctac ttgatgcaaa cttcaatgaa
     7801 catccctgcc tcagaaatca tttccactta tgtatacaaa gtcggcttgc aatcaggtga
     7861 ttatgcctac tctgctgctg ttggtctgtt caatatgatt attaatgtcg ttttattact
     7921 gattgtcaac aatataacca agcggctaaa cgatggtcaa ggcttgtaat gaaaggagaa
     7981 aattatgaat agtgctttat caaaaatcga ccgtcaaatc ttatggttga atcgagtgat
     8041 tgtaactttt ttagtcgtca tcaccattgt tccgctgatt tatgtactgg tagcttcttt
     8101 tatggaccca gctactttga tcaataaagg tataagcttc aatccgaaag attggacaat
     8161 acagggatat caacgggtat ttgcagatga ttccatttta cgcggttttg taaattcgtt
     8221 gttttactct tttagcttca gcttattgac tgtatttatt acgatgatca ctgcgtatcc
     8281 tttgtctcga cctaacttgg cggggaaaaa gattattatg actttttttg tcattacaat
     8341 gttcgtgggt ggtggcttga tacctaccta tttattggta aagaacttgg gcatgttaga
     8401 tagtgtatgg gcgattatcg taccaggtgc tataaatgtg tggaatatta tcttagcccg
     8461 tacctatttt agtgctttgc caaaagaact ttctgaagct gctactatcg atggcgccaa
     8521 tgacttgcaa atactgttca aagtcatgct tccattagcg aaaccaatta tgttcgtatt
     8581 gtttttatat gcctttgttg ggcaatggaa ctcatacttt gatgccatga tttacatcaa
     8641 agatcccgac ttacagccgt tgcaactcgt attaagaaat attttgatcc aaaaccaacc
     8701 ttcacaagac atggtgggag ccaatactgc catggcagaa atgaaacaaa ttgctgagtt
     8761 gatcaaatac gcaacgatcg tcatttctag tctgccatta atcataatgt atcctttctt
     8821 ccaaaaatat tttgataaag gtgttttagt tggttctgtt aaagggtaag tattgttcac
     8881 tatttgtatg aataaaaatt ataaaggaga ttttaagatg aaagcaaaat ggatgctgcc
     8941 aatcgttttt acttccgtac taattttggg ggcttgtgga ggctcaaaag aaaagagtaa
     9001 atcaagccct gattatgaac tagaaaatgt ctcttttcca ttgaaagaaa aagtatcttt
     9061 aaaaatgatg tctcaaagtg cccctttggc tcccaatgat cctaatgaca aattgatttt
     9121 ccaacgatta gaagaagaga ccaatctcca tattgattgg acaaactaca gtagtgattt
     9181 tgccgaaaaa agaaatttgg atatcgctag tggtgattta ccagatgcca tcttcaacgc
     9241 cgctgcaggt gactatgatt tattaaactg ggcggaaagt ggcgttattg taccgattga
     9301 agatttgatc gaagattata tgccaaatct gaagaaaatt tttgatgaaa accccgaata
     9361 ccgacaaatg tctactgcac ctgatggtca catttactct atgccttgga ttgaagaatt
     9421 aggcgaagga aaagagtcga ttcatacagt aaatgggatg gcttggatca acaaggagtg
     9481 gttggataat ttgggtcttg aaatgccgca aaccactgat cagttgatga ctgtgttgga
     9541 ggctttcaag acgcaagatc caaatggtaa tggtgaagca gatgaaattc cttttagctt
     9601 tattaacaat ggaggaaacg aagacttaaa atttttaatg ggggcattcg gtctaggtga
     9661 taatgatgac cacttagtcg ttgataacga tggtcaggta caatttactg ctaacaaaga
     9721 agggtataaa gaagccatca aatatttcaa tgaaatgaat aataaaggtc ttattgataa
     9781 agaggctttc gaacaagatt ggaatacgta tgttgccaaa gggaaagaac ataagtatgg
     9841 cgtgtacttt acttgggata aagcaaatat cacgggtgca gatgatagtt atgacgtctt
     9901 gccagtctta gcgggaccag atggaacgaa acatgttact cgtacgaatg gcatgggttt
     9961 ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac ttggaactta cagctaggtg
    10021 gatagataaa atgtatgaac cgttacagtc tgtccaaaat aactggggaa cctacggtga
    10081 tgaagcacag gcgaatattt ttgaattaaa ggatggtatg ttaaaacatt tgcctttaga
    10141 ggggacagca ccgggggaac taagacaaaa aaccgaagct ggaggaccat tagcagttct
    10201 tgattcttat tacggcacag tcactactat gccagatgat gcgaagtggc gtttagattt
    10261 gatgcatgac acgtatttgc catatattac agaagacaat atctatccac gtgtcttttt
    10321 agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg gatatgtggg attacatcta
    10381 tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat gaagaatggg aagaatacct
    10441 tgctgaattg gaacgtgtag gtttggaaga atggattcaa ataaaacaaa ctggctatga
    10501 taattttttg aagggagcac aataagtgtt agtagaagaa acggcgattt tggataaagc
    10561 aaatcgattt attgaaatga tgcgaggaaa agttaaccct cagtatcgac aaaactatca
    10621 tttttccgca cccatcgggt ggataaatga ccccaatggg tttatatatt acaaagggca
    10681 ttaccatctc ttctatcaat actatcctta cgatagtcga tgggggccca tgcattgggg
    10741 gcatgcgcgc agtagtgatt tggtccattg ggaagatcta ccagtagcgt tagccccaga
    10801 tcaaccttat gacagcggcg ggtgtttctc aggaagtgca attgaaagag acggaaaact
    10861 atatttattt tatacaggct gtcaagaaat tgatggtatt agccatcagc atcaatgttt
    10921 ggcggtctct gaagatggta ttcattttag caaatacagt ggtaatcctg tggtagcaga
    10981 aaaacagcta ggtgaaaatg ggctaataca agaatttcgt gatcctaaag taattgttca
    11041 caacgatggt tactatatgg tagtagctac taaatctaca cagtctactg gtagaatagt
    11101 gatgtttcaa tcgtcagatt tgtatacttg gcacttttac tctgtgctgc tagaagggac
    11161 ttcagagcaa ggaataatgt gggaatgtcc tgatttattc catttagacg gacgagatgt
    11221 cttaatcatg tctccgatac aaatcaagaa gaacggactg gaatatcata atatcagttc
    11281 taccatggct tgtattggtg aggtaaactg ggaaacaggt cagatgatag ttgataattt
    11341 ccatgaaatg gattttggaa tggattttta tgcaccacaa acaacaagag atcctaatgg
    11401 tggacgggtg atgattgctt ggatgcagat gtgggatcgt acattgccta cacatgagtt
    11461 aggccatctt tgggcaggct ctatgagttt gccccgagag ttaagagtga aaaaaaatcg
    11521 attggtacaa aaacccatct caactgtata tagtcattta gtttatcaac aaggcagtga
    11581 aaatattgca gtgactgaca catcagtcgt atttcgaaac gcgctgtctg attcttcata
    11641 tttacatcta gtcgcagatt tggagaaagc tgaagttttt acaattgaat tactgcggtc
    11701 taagacggat tgtctcaaac tagcctatga cactgctaca caggtttttg aattggatcg
    11761 tcagaaacta ggaagagagc ttacaggggc ggaagaagac cctctgaatg tacgaaaagt
    11821 tgaagtacct ttgattgata atcagctcgt tcttgagatt tttagagata cctcatcaat
    11881 tgaagtcttt attaatgggt tagaagttat gacggctact ttctatgagc tggaaaaagc
    11941 tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt caagcttttg aaacagcgag
    12001 tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt atttaatagg ttttgaagga
    12061 taatgttttt agaaaagaac agatagctag atttcccatg gatttgctat tagtattttg
    12121 aaaaaattag taatttatga caaaattcat tatactaaac ttgtgcagaa atgtgaggga
    12181 tcaactatga aagcaacaat gaaagatgtc gcaaaattag caggtgttgg agtaggaact
    12241 gtttcccggg tattgaataa cggttctgtt aaagcttcta ctagagaaaa agttgaagca
    12301 gcaatgacag agttaaacta tcaaccagat ttttatgccc gggggttaaa gatgaagcat
    12361 acgaacacgg ttgctttgat tctacccacg gtatggcatc cattttttgg cgaatttgcc
    12421 taccatgtag aaacagcatt agaaagacaa aactacaagc tttatttgtg taactccagt
    12481 ggtaatagtg aaaaagaaca agaatatatc cagatggtca gccaaaataa agtagacggc
    12541 atcattggaa ttacttattc agatatcgat gaatacattt cgagtaatct gccttttgtt
    12601 agtattgacc gttatttcac tgaagaggtg atttatgtga ccgctgacaa tgcggccggt
    12661 ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc agaatgtagc atatatcggt
    12721 gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa aatattttga aatcgagtgc
    12781 cgtcaactgg ggatttccta taaagcgtta gatatgttag aacctttaga ccatctctca
    12841 gaacgtgtaa caaatttttt gttagagaat cccgatatcg atgggatttt tacgatcaac
    12901 gatccaatgg cattagctgt cattgatatg cttgaaaaaa tagggaaaaa cgtaccagag
    12961 gatgtccaag ttatcggatt tgatggtcaa aagatgacag aaggagatcc ttatctagtc
    13021 tcaacgattg cccaacctac aaagcaaatg gcggaagtgg cagtggcaaa attaattgct
    13081 gtcattaatg gagagacagt agaaaaacgt accgtattgc cgattgaatt tggcgaaggt
    13141 gacacaacga aacctttagt gagaaacgat tttgcttagt gcaaatacgt ttcttttttt
    13201 gaaaatgagt gaatgaaagg tgtagataaa atgttatatg gtggaataga agccggtgga
    13261 acaaagtttg tctgtgggat tggtaatgaa caattacaag tgatagaacg gaaaagtttt
    13321 cctaccacaa caccagaaga aacgatggag caagtgtttg atttctttga taagtacaaa
    13381 ggaaatatcg catcaattgg tgtaggagca tttgggccta ttgatattca aatcgaatca
    13441 agaacttacg gatatatcac caacacaccg aagttagctt ggcaaaatta tcattttgta
    13501 ggagctttgg aaaacgcctt gtcggttccc atctattgga ctaccgatgt aaatgctgct
    13561 tgttatggag aatatatggc agggtatgga aaaggtaaaa atagtgttct gtattacacc
    13621 gttggtacag gtgttggtgg tggtgctgta gtggatggga aaatagtcgc aggttttagt
    13681 catcctgaaa tgggacatat gctcttacaa cgtcataatg aagatcaatt tgaaggaatc
    13741 tgtccttttc atcatgattg tttggaaggg ttagcatcag gacctgcgat tgaaaaacgc
    13801 tttggaagaa aagcccagac tatctcattt gatcatcctt attggacgat tgaggcagat
    13861 tatcttgctc agtgtgtgta taacacaacg ttactatatg caccggaagt aataatttta
    13921 ggcgggggtg taatgaaaca gccgcaacta ctcgagttga ttcgccaatc gtttaaagaa
    13981 aaaatgggtt cctacgtgga tacgcctact ctcgaagaat atctactaac tccaaggctt
    14041 gctgacaatg cgggcttgat tggctgccta gctttagcaa taaagaaact caatcattag
    14101 aatagtattt attagaacta ttcataacat accggaagtt taaaagggta ttctgaaact
    14161 taaatagtct caattcattc ttctttcttg agaatctgag tagagacttt tattctgttt
    14221 caaattaata taattacgaa atgatattga gtacaagaaa gttcttttta ccagatcttt
    14281 taaatcgaaa aatctgatat atatatttat agtactaaaa atctgattag ataaaaagct
    14341 aattcaatag gaaaataaag gtagtgaata aaagcaaagc ccttgttagt agttaatcta
    14401 acaagggctt tggtagggaa aatggtagga aaccatctta ttttttacga aaatcaggaa
    14461 ctttagtaat tgaataatgt tgatttatag gtattcctca tccatattat gttggctctt
    14521 tattcccact ccactgttgc aggtggtttg ctggtaatat catacacgat acggttaacg
    14581 tgtgcgactt catttacgat acggacactg attttttgca agacttccca agggatacgg
    14641 gcaaagtcag cggtcatgcc gtcaatagaa gtgacagcac ggatacctac agtgtagtca
    14701 tacgtacggc catctcccat aaccccaaca gagcgaatgc ctggtaggac ggtgaagtat
    14761 tgccagatgt cgcgatctaa accggcattg gcgatttctt cgcgcaagat agcgtctgat
    14821 tcacggacga tttctaattt ttcttctgtc aattcaccaa ggacacgaat acctaagcct
    14881 ggtccaggga atggttggcg ccaaacgatg ctgtcaggca tgcctaattg ggtacctaat
    14941 tcacgtactt cgtctttgaa caatgtgttc aatggctcga tcagcttgaa ttgcatgtct
    15001 tcaggtaatc cacctacatt gtgatgtgat ttgatggttt gggcagtttc agttcctgat
    15061 tcgatcacat cggtataaag ggttccttgt gcaaggaaag aaacgccttc ttcaccggca
    15121 agtttggttg cttcatcatc gaagacatat acaaattcat ttccaatgat tttacgtttt
    15181 tcttctggat cagacacgcc agcaagtttt gataagaaac gttctttggc atcgactttt
    15241 ataatgttca agccaaattt tccgccaaga ctttccataa cttgttctgc ttcaccttta
    15301 cgcaacaata cgtgatcaac gaagatacat gttaattgat cgccgatcgc tttttgtaaa
    15361 agaacaccaa caacagagga atctactccg cctgaaaggc ctaataaaac ttttttgtca
    15421 ccgacttgtt cacgaatttt tgcgatctcc atgtcgatga agttatccat tgtccagtca
    15481 ccagtacatt ggcagacatc tagtgtaaaa tggcgcaaca agtcatttcc atattcggaa
    15541 tggcgaactt ctgcatggaa ttggattccg tacattttgc gttctgcatt ttggatcgat
    15601 gcgatggggc aatctttgct ggtagcaacg acatcgaaat cagtcggtgc ttgggtaact
    15661 aggtcaccat gactcatcca aacggtttgt ttttcaggag tgttttggaa aagggccgct
    15721 tctgcagaag tgatttccaa ttctgctttt ccgtattcac ggtttttggc tggtttaact
    15781 tttccgccta atttataagt aatcaactgc ataccgtaac agattcctaa aactgggatc
    15841 cccaaatcaa aaatcttttc atcaatacca aaggccttct catcataaac actgtttggt
    15901 ccgccagaaa ggatgattcc tttagggttc attgccttta cttcttctgc ggtaatgcgg
    15961 tggctcatca actctgagaa aacaccgaac tcacgaatac ggcgagtgat cagttggtta
    16021 tactgactac cgtaatcaag tacgataatt tttggctctt cgtcaaatcg tgttggtgaa
    16081 gacaaatttg aataaaactt agtccgatat gcggcgcgtt ctgtgcgccg catatttttt
    16141 tagttttcaa agatcagacc ttgttgtaaa tagatccgtg cccgaaagtt ataaaagttg
    16201 cgataaccaa acgcaattcg tttaatcagc ttgatcttgt tattcagccc ctcagtgacg
    16261 ccgtttgagt gggacacctt aaaggcattt gaaatacccg attggtagcg atggaagatc
    16321 gtgaatttct ttttaaacga ctgaggtaac gtagatgaaa ttgttttaag ggtttcttga
    16381 aagccttccg ta
//
LOCUS       DADVXE010000057        16308 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.058, whole genome shotgun sequence.
ACCESSION   DADVXE010000057 DADVXE010000000
VERSION     DADVXE010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.058"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            44..1195
                     /locus_tag="KB913_002094"
     CDS             44..1195
                     /locus_tag="KB913_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBB6820436.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVFLLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(1304..3343)
                     /locus_tag="KB913_002095"
     CDS             complement(1304..3343)
                     /locus_tag="KB913_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBB6820437.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDQYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGEKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKDDDDSATKRASELLQYLNQNYQ"
     gene            complement(3401..3958)
                     /locus_tag="KB913_002096"
                     /pseudo
     CDS             complement(3401..3958)
                     /locus_tag="KB913_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            complement(4497..4703)
                     /locus_tag="KB913_002097"
     CDS             complement(4497..4703)
                     /locus_tag="KB913_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820438.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(4719..5333)
                     /locus_tag="KB913_002098"
     CDS             complement(4719..5333)
                     /locus_tag="KB913_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBB6820439.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(5480..6163)
                     /locus_tag="KB913_002099"
     CDS             complement(5480..6163)
                     /locus_tag="KB913_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBB6820440.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(6272..6730)
                     /locus_tag="KB913_002100"
     CDS             complement(6272..6730)
                     /locus_tag="KB913_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBB6820441.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(6814..8577)
                     /locus_tag="KB913_002101"
     CDS             complement(6814..8577)
                     /locus_tag="KB913_002101"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBB6820442.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(8798..10258)
                     /locus_tag="KB913_002102"
     CDS             complement(8798..10258)
                     /locus_tag="KB913_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820443.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(10466..11392)
                     /gene="glsA"
                     /locus_tag="KB913_002103"
     CDS             complement(10466..11392)
                     /gene="glsA"
                     /locus_tag="KB913_002103"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBB6820444.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(11415..12842)
                     /locus_tag="KB913_002104"
     CDS             complement(11415..12842)
                     /locus_tag="KB913_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6820445.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(12873..14087)
                     /locus_tag="KB913_002105"
     CDS             complement(12873..14087)
                     /locus_tag="KB913_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBB6820446.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(14428..14670)
                     /locus_tag="KB913_002106"
     CDS             complement(14428..14670)
                     /locus_tag="KB913_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6820447.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(14702..15259)
                     /locus_tag="KB913_002107"
     CDS             complement(14702..15259)
                     /locus_tag="KB913_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6820448.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(15272..15460)
                     /locus_tag="KB913_002108"
     CDS             complement(15272..15460)
                     /locus_tag="KB913_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBB6820449.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(15473..16039)
                     /gene="amaP"
                     /locus_tag="KB913_002109"
     CDS             complement(15473..16039)
                     /gene="amaP"
                     /locus_tag="KB913_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBB6820450.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         4635 a         3318 c         2757 g         5598 t
ORIGIN      
        1 tatgctaagt tcgggctata ttttatacaa aggaatgatg agaatggaat ttattggtat
       61 tttatgcctg atattgattt caacaacgat tggctcacat atctcgcgga gattaggtat
      121 cccagcagtg attggacaat tacttgttgg tgttttgcta ggccaagctg gattgaattg
      181 ggtcaaacct gatattctag tccatgactt ttcggagatt ggtgtgttct tattaatgtt
      241 tttagctggt ctggaaagtg atttatctct tttgaaaaaa tatttccgac ctggtatgtt
      301 cgttgctttg cttgggatca tcttcccggt tgtttttggc tggttgacag gcaaagcatt
      361 ccaagtttcg ggaaatgaag cgattttctt tgggattatt cttgcggcaa cttctgtcag
      421 tatttcagta gaagtattaa aagaactaaa cgtagtgaat acaaaagaag gatcaacaat
      481 tttgggtgct tctgtggtag atgacatttt agtcgtttta gttctaagtt tcagcctatc
      541 ttttctaacg ggggaagctt ctagcaatgc ttctttaccg cttgttttga ttgaacagct
      601 aatttatttt gtttttattt tcttattagt caaatggatt gcgcctttcc tactttcatt
      661 tgcagaaaaa gtgtacgcaa attcttctat tatcatcgta tcgctagtta tttgtttagg
      721 aatgtcttac gtagcggatc ttgttgggct tagctctgtc attggtgctt tttttgctgg
      781 gatagctgtc agtcagacaa aggttaaaga agaagtatac cacaatgtag aggctttagg
      841 atatgcagta tttataccag tattttttgt cagtgtagga ttagaagttg atttttctga
      901 ctttagtgaa caactactct ttatttctat attgacgctt gtagcgattt tgaccaaatt
      961 gcttggaggt tattttggtg ctcagattgc cggtttttct caacatagtt cattgatggt
     1021 cggtgctggt atgatttcgc gtggagaaat ggctttgatc attttacaaa ttggacagca
     1081 aagtcaattg atcgaaccac agtactattc acctttagtt atcgtgattt tattaagtac
     1141 acttatttct ccacttgttc tcaaatattt tacaaaaaaa gtttatgaag tgtgagtaaa
     1201 tcaaaaagaa gttgtgaaag agacatcgtg aaaaccgttt atttgaaaaa aggactgtga
     1261 cgataacgcc acagtccttt tactgtactt aaaaagcaat tttttattga taattttggt
     1321 tgaggtattg caatagttcc gatgctcgtt tggttgctga atcatcatca tctttatttt
     1381 ccaacatgct gaccatcata taaccttggt tatcaagatt gaaagcaaac aagaaactgt
     1441 tctcttgccc ctttacatcc tgtttttctt tgatttccgc tgtaccagtt ttcgctgcca
     1501 acggaatccc taaagcagaa agagaatgtg ctgtaccatt tacatcttgc acaacttctc
     1561 tcagatctgg cacgatcgtt tgtactgctg tttcgctgat gacattcttc ttatcttttg
     1621 tctctttatc tgcaatcaat ttaggataga caagtgtgcc attgttggta aaaacagaat
     1681 acattgctgc ttgctggata ggagtaatta gaagttcgcc ctgtccatat ccagtatcag
     1741 ctagcaagat atctgagtta aagctatctt cattagaaat ttgtgctgga ttcatactaa
     1801 ttggcaaatc aaggtcttca ccaaaaatga atttatctaa gcctgtacga aattttttct
     1861 cacccatttt caacgtttct tgtgccgcat atatattatc ggaatagatc aaagcagttt
     1921 ttaagtctac ttgtgataca tcactactga cacgcgttgt tttaaaagat ccccaagaac
     1981 tgtctttttg ccatttaagc ccgttgatcg tcaacacttc atttggatcg atagtgccgt
     2041 tgtcgagacc gattgctgct gtaattattt taaacgtaga tccaggagca taacctgtcg
     2101 caaatcggct gatgaatgga tgttcaggat tttcttcata agctttgtaa tcttcttgtg
     2161 agatcccgtt tgtcattttg tttggatcat agcttggaga gctagcaagc gcaagaagat
     2221 caccggtttt tggcgttgtc gcaacagttg atccagcttt tcctcctaga ctgtcaaaag
     2281 ctgttttttg tgccttcgca tcgattgtca atttgatatc tttgccattt tgaacttcat
     2341 gttcgatcag aacttttttc tctacaccgt ctgcatctgt aatgcttaat ttctcacctg
     2401 ttgtcccacg aagatcctta tcaaaagcca tctccaaacc tgagcgaccg atttttccat
     2461 tactgcttaa ttctggattc ttatcaatat cttctgctgt gatatctccc acgtaaccaa
     2521 tcagctgagc agctgcttca cccaaaggat aatatctgcc gtctacttct tgaatggtag
     2581 ctccagctgg aagttctggc gttgctccat caatgatttt caatgggaca aagtaatcgg
     2641 gttgtaccca gctttgtgaa atcgcctgat tgatagcatc ttctgttaag tcgaaggagg
     2701 aagcaatcgc tttgatattg gctgtttttt cgcctccatc tccaagttta cttggaacga
     2761 ctcctaattg ttttagtttg cctgttgttg ctaatggttc accatttcga tctataatat
     2821 tccctcttgc tgcttcttgt gtggtcaggc ttactttgtc atttccttcc atttctggaa
     2881 aaaccaagtt gggttgccag ttgatcgtgg tttgaccatc atttctgtct aatgttcctt
     2941 tataagaaag atctttcaat tcacctaatg aggtattcat ctttgcttta tatgaaaaac
     3001 tgtaagtaga atcgtctttt ttatctactt ttagattcga tatctgaagt cctttgacat
     3061 cagcagcacc gtatatattc tggtattgat ctaagatctc tttttcagat aatgcacttt
     3121 tatttgccgc cttttttgat gtcatttctg cagctttgtt ataatctccc ttgttcaaag
     3181 cttggacaaa ttgctcaact gtcttttctc cagcttctac tgcttgggtt tcttgatagt
     3241 gctggtagta aaaataaccg ccacccgcag ctgctattaa gatcactgcg ccggcaatat
     3301 aagcgcctgt tcgatttttg ccgtgcttgt cacttctttt cattttttcc tccttctctt
     3361 gcttgtcatt cctttatttc actatttata cctgtttatt ctaacatatg tctttgagga
     3421 aatccatacc acaatccaga agcacacttt ctggaaggtt cgtttggata ctaccaagta
     3481 atttcccaac cgctttgggt agcttgaata ttgaagttac gtctttcagc tgctgagaga
     3541 tagctttgat cacttgctgc tgccttctga tcctcccgaa gtctccttct ttgtcttccc
     3601 gaaatcgagc atactggagt aaagtattac catccatcac ttgctctcct ttgtttatat
     3661 atacgccatc taaatctaga gatttttctg catcgatctt gactccacca ggaaacagtt
     3721 cattaacgca atcgataaaa tcttgaaatg tgatacttgc ataataggga gcttcaaatt
     3781 tgaaattttc ctttaatgtt tgatttaata aatcaactcc cccataagag taagctgcat
     3841 ttatcttatt cattccgtaa cctggaatat cgacatatga atctctcatg atagagatca
     3901 gttttgcttg ttgtgttttc tggttgtatt gtgcaaccag aagtgaatcc gagcgacctc
     3961 caccaatcga tcttttttca ccgcatctcc tcctcacaca gcaatccact tgtcaggtga
     4021 ggagcgagtt tgtctcatca aataagtcag tcacaaaaat ataaagaaaa ggtcagaaac
     4081 cttttcgaac aagaattctg acctagcatc atctcatcgt ccgagtttta gcactataca
     4141 acgtaaagaa aacattctta gctattggaa aaagccttaa tccaacagtt tctgttttac
     4201 ccattggcga ctttcgacgt ttctgggcaa cagcctatgt ttgtatagga gcctcaccta
     4261 acaaggttat tactatattc tatttacgag ttcatgatag acttttccta atgattaggc
     4321 aatggaattt gaaatgaaat agtgaaattt aacaatcttt aatatttttt agaaaaaaat
     4381 aacaaataag ttgaaagaat cccgttgcaa attctttcag ttgcaccagg attctttgat
     4441 aattttttag ttttatgtgt ttttttatat gttttttcac ttttcggaat aaatatttat
     4501 ttgttaaagt aattaaacaa tccgctaatc gtttgatctg gcatttctat ttccttacca
     4561 tctaaagtaa cagtagtaac gacaaaatgg tcttgcaatg gcggaacttc taagtactgc
     4621 ccttgcagaa aatcattcac tgtttcatat tcttttttca tttcttttga atctgtcgat
     4681 ggtttatagc ttatttttaa cataactagt gctccttttt attcgggacg tgcaatcgtg
     4741 aaaatttctc ctattgctgc ataatcattt cctgccaaac ggcttacagc attcaatttt
     4801 cttggatcga tccttcctgt cttatcatca tagactgttt catttaaatg atatttctgt
     4861 acttctagca aaaataaatc agctgttact ttatttttat tccgtatctc gacatgttca
     4921 tataaggatg tttcaaaacg aacttttgct tctgtcaatg ctggtactga aatgattact
     4981 gaatcagtta aagtcaagtc agtcaggtac agttcgcttt cctcattagg cagattggct
     5041 gctgttttat ttacttcttc tacgttgtcc tcatcaagga tatggataac agcttctctt
     5101 gtctcaagaa tattctttgc tgtgtctttt actgcatctt gttttctctg gatcgccaag
     5161 gataagatgg gtcgattcga actgacgata ttgaagtaac tgaagggtgc gatattcact
     5221 atatcttttg ctgatttagt cgttactact gctactggtc tagggatgac tgaaccaatc
     5281 agcaacttgt aattttcacg ttctgtcaat tctgaaggac tccgttcaaa catggtttcg
     5341 ccttctttct ataaaattcg ttaaaaagca gatcttgaag acaaaatgaa aagtaatgct
     5401 tttttcatct tcttagaatc tgctttaaac tatctatcaa tttttctttt ttgtcaagaa
     5461 tctgtgccgt gcgtgttttt tagttatttg ctttacttgc ggcttcgaca tatcttttag
     5521 tgatcaattg cggacgggtg ataatagatc caactacgac tgaaaaagca cctaattcat
     5581 atgctttctc tacttgttca ggagagtcag tatgtccttc cataattact gggatatcga
     5641 cttgttctat gatttgattc aataaatcaa aatcaggtgt ctgcgtcttt cgtgaatatt
     5701 ctgtatagcc tgctaaagtc gtagacaaaa gatcaaaacc atcttcttgc gcttgaagcg
     5761 cttcctcaaa agtcgaaata tctgccatag ctaaccgacc gtgttcgtga atcatttgga
     5821 caagttcagc agttgttttt tctgtcggac gtttacgaga agttgcatcc agtgcaatga
     5881 tttctgcttg cgtctccaaa agttcttcca cttctttttc tgtcgcagta ataaacactt
     5941 ctgacccatc gtaatctctt ttgataatcc ctattaccgg taaatcaacg attcgcttga
     6001 tttcattgat atcttctgtc gtatttgctc gaataccaac tgctccgcct tcttttgcag
     6061 ccaaagccat tctccccata ataaaagaac tgtgtagcgg ctcgttttcc aaagcttgac
     6121 aagaaacgac gactccgcct ttgatttgtt ccagtgtatc cacaatatct cctccagtaa
     6181 tgttatataa aaatacagct tcatataaaa atgtaaccct tttctattca ggagacaata
     6241 atgagctatt tctttcagca gacctttctt actaaaagaa aattacttca aattcttcgt
     6301 atacgaccag cttctcttct gtaaattcta tgttcaacgc ttctttataa gcatgtttaa
     6361 aaaactcagc atggactttc cgccaataag ctaatgtccg atccccttct ccttctttcc
     6421 aagcatgctc tttcgtgact tcactaaaag gcaagatggt cacatttata tttttgatga
     6481 tacaaactgg ttcatttttt ccattcagga ccacgtctaa ttgaccaact tttggtaaag
     6541 gctcattctc ttgtttatac agatcgtaac cacttgatgt accagtcttt atctttttta
     6601 caactagttc gctcaactcg tctgccattt tttctgtatc cccaaatgaa aagaaaccta
     6661 atttttctga ttgataacta ggatattttt cttggaactt tttgacatat tcttctactt
     6721 gctgatacat aacatccacc cctttgcttt ttataatgaa aaaaccatcc agatactagt
     6781 ataaacaatt atctggatgg tgagcataat gaattattga atattcaaga cacgcagact
     6841 atcttcaacg atttgttttg gtgttaaatg ataacgttca taaagctgcc ctacaggaac
     6901 gctatccgtg aattctttct ctgcaccaaa atttaatacg ttcattgaag aatcaccata
     6961 ataacgactg atattttcgc caaatcctcc tgacaaacta ccatcttcta atgtgatgac
     7021 taattcgtgt gtttctttta atttatctaa tgtttctacg tcattttctg tgatcgttcc
     7081 tggattgatc aacgttgctt cgattccttt ttttctaaaa gcttttactg tttcttttcc
     7141 taattcaaga aaaccgccta aagctaaaat tgctactttt cctccattat ttactgtttg
     7201 ataggctgga atactataat catttgcgat agctgtacca tgttctacac catgtgtagg
     7261 aattcggatt gctacaggct gcgctgtttg ttcgaacgcc caatctagca tagagatcat
     7321 atcctctttt gttgctggag caagatattt gatgttcggg atacttgata agtaaggaat
     7381 gtcaaatgtt ccttggtgtg ttcggtcact agctgagatc gttccgccac cgactaaaat
     7441 aatcactgga ttctcgttga tcgctaaatc atgtgataat tgatcatatg cccgttgcaa
     7501 gaaagtactt gattggaaga cgactggacg tactccctga gaagccaaag cagaagcgaa
     7561 agtgatagag tgctgttcag cgatccccac gtcaaaataa tgatctggat gtttttcttg
     7621 gaatgttttc agtccaaagg cgcctggtat cgctgcattg actgcggcaa taggagctgt
     7681 acttgtttgc attttcttat ccaaataatc catgatgatc atattaaatg tttctccaga
     7741 agttacttgc tttgcctccc cggtggacag atcaaatggt acatgccaat gatatttcat
     7801 tttattatcg attgccggct gataaccgcg acctttttcc gtatggacgt gaagtacaat
     7861 cggatgatca atatctttta cttcttcaaa taaacggatc accgtttcca gatcgtttcc
     7921 attatccacg taacgataat caaatcccat tgctttaaat aggttattgc tgcttttacc
     7981 gttggtttga cgaagctcag ctaagttttt atataaactg ccatgattct catcaataga
     8041 catctcatta tcgtttacta atacgattag attggattgt aaaacaccac cattgttcaa
     8101 tccttcaaaa gctaagccac cacttaggga gccgtcaccg ataaatgcta ccacatttcc
     8161 tgattctttc ttcagatctc tcgctttagc taaacctgtt gctaagctga tagatgtaga
     8221 tgtgtgcccc actgtaaaat agtcatgttt actttcatgt tggttggaat atccgctcac
     8281 ttcacggtaa tgtccttttt caaaaccatt ttttcgacca gttaaaagct tatgaccata
     8341 agactgatgg gaaacatccc aaacgatttt atcctttggt gaatcaaata cataatgaaa
     8401 cgcaatcgtt aattctacta cacctagatt cggaccaacg tgcccaccta catcgctgtc
     8461 cttttgcaag attttttggc gcatctcttc tgccaactgt ttcatttcct caacagataa
     8521 ttttttgaca tctgcggggc tattgattgc atccaataca tgtaatactg tactcataat
     8581 acattctctc ctccgtacta tcttctttta atgaaaatag atttgttaca ctttatctat
     8641 tctactactt agagttgact ctaagtcaat agcattttaa aaaaatttca gagaaagctt
     8701 gttatataag tagatcttcg cacgaatcag gactcaaata aaaaccttct acagacaatt
     8761 aaaaagcttt gtagaaggtc tcctaattaa ggtctcatca agaaatatgt ttttttaata
     8821 ggtgaagttc ctgagcaata tgatacaaat ggatgtttgc accttttaat gagattggat
     8881 agatctttgt cttttcagtt tctaatccat tttgatagct agcagcatcg cacaaaacca
     8941 ctcttttttt cgcacataga cattcatcag gcaattcttc taatgaacga aataaaatag
     9001 gatttatttc agcgatgcct tcttccgcat acaaatgaaa ttgggttcga taaaaaaatt
     9061 gtttgactga actttctgaa acaacaaaaa tttctatttc ctgtctcccc gcttgttcac
     9121 tgttgatcaa agaaagactt ttgacgaatt ttcgaatgaa attttcattc catcttagtt
     9181 ggatttgatt tttctttttc cactcttcca atatttctac aatttttccg tacagaagtt
     9241 gttctttttc tgatagaaga tagatccttt ccggtaaaaa tacttgtcca tctgcccaca
     9301 acgtacggac aaattgtaaa aaggattgct tgaaaataaa attttctgca tcgtcgattt
     9361 cagcgatact aataatctgt aaaatcaatt cattcagtga taggtcattg agaacaaaat
     9421 ttttataaac aacttcgaaa tcttttctta acagctccat gttctcattg gtataatttc
     9481 tactgttgaa caaagaaaaa atataataga catcttcttc ttgtaagtct agaattcctt
     9541 tttgctcttc caatccttga cagactaatt gaaataacgg cttcgtttct gcgcttttct
     9601 tatcttcttc tttcagtcca aggggaaatg cctttcttcc gattgcgatc tctattcctc
     9661 gtatgataaa ggacttttca tcttccgaat atcttctttt aaaaaaatga gtctctacat
     9721 aatcaatcaa ctcgttacaa gcttcttcta catacggatt tttattttca tagccttccc
     9781 aattgacata acgtactaaa gctagcaaga tgttccgcga gtcaaattct gggataatga
     9841 tttctttatt tttcaaataa tcattttctt taaaaaaatc caatacgatt tttttgattg
     9901 tatatacttt gctcaaagaa ataaattcaa gatcagccag ttctgtactc gtgaatatac
     9961 cattaaaata ataacttaaa aactttaaaa aataagattg accgtacaga aactgtgtga
    10021 gctcagaaag agcaatacca tgtttgaata cgagtttata cttatgcttc tctcttactt
    10081 gttcttttat acaatattct agacactcgg ctagactttc tagatcgtga aggatcgttg
    10141 gtgtagtcac ccttagagaa atagctgttt gttcgatgtc tatttcttgg aattcaaata
    10201 attgttcaca cagatacact tttctaaata tatttcgctc gatgtaattt tccagcattc
    10261 ctgatacacg cctccagttt ttcttatgat tttatttaat catatctgta aatcgtattt
    10321 ttgtttcctt tttatttaga aaagcccttt caaaaaccaa taaaaaaaga aactgggaca
    10381 aaagtcaaac aagctcacaa tttcagcctc attgtaggta gctttgagcc gtttggactt
    10441 ttaccccagc ctctttcaag aatggttatt caaagatgtc agcgtctagt tctttgacta
    10501 catctttcaa caattggata ccagctgcgc tgttaccaaa tggatctagt gccgggctga
    10561 agacacctat gccgtaacga tttggcacag ctgccatcaa cccgccgcct acaccgcttt
    10621 ttgcaggtac accaacatgg acggaaaact ctcctgattc atcatacaaa ccagcagttg
    10681 tcataattga tttgacgatt gtagcacttt cttcagtaat gatttgtttg ccattccaag
    10741 gagcaattcc tttatttgcc agcacagcag ctaattttgc tatgcctgta gcggtgacat
    10801 tgagggagca ttgtctgaaa taagcatcga gtatctccgg tacgtctcct tcgatcattt
    10861 gattaccttt catatagtaa gcaagagagc gattgatatc acctgttctt gattcagaat
    10921 gatagatttc ttcattcaat gtgatattag gatcatcaca gatctctttc ataaatgaca
    10981 agattcgctc aaatttttca tctgcatctt taccggcaat caacgaggtt gttgcaatcg
    11041 ctcctgcatt aacaaaagga ttcattggat gtttgcgatg attgatttcc atattcatga
    11101 tagaattgaa ggcaaaaccg gttggttccg tgttgattgt ttgaaagact ttttctattc
    11161 cgttgtcttt gattgctaat aacaatacgg gaacttttga catgctttcg atggcaaagc
    11221 gcacatcggc gtctcctccc tcaatcagtt gttttgtatc caaatcataa atcgccatac
    11281 ctaattgttt gggatccact tcagctaatg ctggaatgta atccgccact tgtcctgttt
    11341 gataatagtg gaaatttttt ccaatcaatt gttctaattc ttttacttcc atttgaataa
    11401 ccagctttca ttttttattt ttctgcatgc tggaatttat gacggcatgc gtagatcgta
    11461 aatggaataa ctaagacgat aagataagaa acaatcagaa tcgtttcata aatcccatgc
    11521 tgtccagctg cgatactagc aggtggaaca aatgagatac aaaaagcaaa aagtgaagtc
    11581 aaaagaccta aacaagcaac gattactttt acaacttttc cgcctggaac ctgataggct
    11641 ctttcaagac tgtcatcttt aaaaaccagc ttcaaatagc ccgcgaaaaa cataaagtac
    11701 aacatcaggt agattacaac agtcaatgac atcgctgcaa gaaatgaaag attattcccc
    11761 ccgccgctta atgtaaagac ggctgcccag attgttgcaa cgatcccatt tgcgatcatc
    11821 aaatgagcag gaacaccgtg tgtgttttct tttgcaaaat attcaggaag taatccttct
    11881 tctgctgcta cgtgaagtgc ttttgaagga gaggttaccc aagaagcaat ttctccgatg
    11941 acacctaaac aaacaagaat cgcaagaatt ttcgcaatcc atgcaagatt tggatcaatg
    12001 tgtcttaata ggaattctaa cgattgaatc acccctgtat taagagacaa accatgttga
    12061 ggtactgtag tagcgacggt caatccgcca aaagtatcta aaatgattgc cagaataacc
    12121 aatacaaaca ttgctaatgg ataatccttt ttagggtttt ccatttcatt tgcatgactg
    12181 gcagatgttt ctacgcccat atatgctaaa ataaaggaaa caaaaacaac cagcgtaggc
    12241 aatttcgaaa aatcaggaat caatgttttc atagacagta tcgtttgtag tggagcgcct
    12301 gaagcgacat aatggatccc taagccaaac aagactaatg ctggcaacaa gataccagct
    12361 acaaaaccga tccgagcaat caatgaagtg tatttggttc cttttaactg tgagagtaaa
    12421 atagcccaga aaataatcaa taggattgcc aatttcagat atttattgtt ttgtatagca
    12481 ccaatacccg ttgcatagga taatgcacca gttaagaaat acagcatggt caagtagcca
    12541 actgttatct caaaccattg gaaaaagatt gcggcaaaac cgaatcgttt tcccaatgtg
    12601 cgactgaccc aagtatagac accgcctttt tcccatcctt tcaccgttgc catctctgct
    12661 gcgcacaatg ccacagggat aaaccatagc aaaccgccta ataacaagaa aaatactaag
    12721 ctgaagcctg aggtcgcgaa tgtgggatat tcatataatg aaacgaccat tgagatggtc
    12781 atagccaaaa agccaaagaa cgttaatttt tttgcaggaa ttttcgtttt gctttgttgc
    12841 atgaatcttc ctcttttcta tttgaatttg tttcaattga gtttgttgcc aaagaagaaa
    12901 aagtccaatc cttcttcttg ttcttctttt gtagtagtga tcgttgtaaa gtgcatcgcc
    12961 gattttaaaa tcactgttgt cagcacatag gcatacacgg cagtaatgat gacaccaatc
    13021 acttgaatcc ctaagaagta ccagctgctt ggattcgtta gtaaatggct gttagatgca
    13081 aagatcccta tcagaatcgt acctgtgaat ccgcccatgc catgaacacc ccacacatca
    13141 agtgcatcat cccattgttt ctttttacga aaatcaacag cagcatgaca gacgataccc
    13201 gcaatgatcc caatcagcat ggcacttttt gcttctacat aaccggcaca aggcgtaatg
    13261 gctgccaatc cagcaacgga tcctgttagt acgtcgacaa aatcaaagcc atttcctttt
    13321 acttttgcaa tgatcagcca agtaatcatc gcaaatgcaa gagcgatgaa tgttgaacca
    13381 aatgcattga ctgcttgttc atctgctcga agtgcaccac cggaattaaa accgaaccag
    13441 ccaaaccaaa gcagtcctgt accgatagca gctgccataa gactgctatg ctgacttctt
    13501 tctcctaaag gaatctttct ttgaccaagt gtgaggatac atgctaaaga gccgaatcca
    13561 gctgtcgtgt ggatgactgc tccaccagcg aaatctctaa atcccatctg atccaaaaat
    13621 ccgccacccc atatccagtg gcaaacaggg aaataaatca gcagattcca aaaaataaca
    13681 agtataatat agccttttaa attcaatctc cctgcaaaag ctcctgtcat caaaggaacg
    13741 gtaatcacga taaacatcag ttggtaaaga aagaacatta aaaatggaat cgttgcacca
    13801 tgaaacatgt tggggaagct tgtaacatgt ctcatcaaaa agaaatctgc cgggtttcca
    13861 ataacaccgc cgatatcccg tccaaaggcc aatccgaatc caccaaatac ccacataatc
    13921 gttgttatcc caacggagag aaaagattga gacatgatcg ttagtatatt attcttccgt
    13981 gctaatccgc cgtaaaaaaa agctagacca ggagtcatca ggcaaaccat tgctgtacat
    14041 aaaatcatga atgctgtatc tcctgtattg ataggtaatg tattcatttt tttcgcctcc
    14101 tttctacgat tacgagtata aaagaaggtg tagttgtttt tttcttctgt ttttttgaat
    14161 taatacttgc atttataaaa gacagacaat taataaaagc ttgatgtgtt gtgctctttt
    14221 tcgtttttca cacaaataaa gacaaaaaat aaacggtctt ctttttatag aaaaccgttt
    14281 attttcgtct ttttttattt ttaaagatat tttttcataa ggaataaaga atacttcata
    14341 taaaatatat aaaaaagaac cgcagcgagt gtcgctacgg ttctcaaatt tgttcttcat
    14401 ttcaacataa gtttttcttc aatttgctta taatttacgt gcaaagaatg aaacgactaa
    14461 tactaaaatg attgcaccga tcaatgatgg aatgatagcc attcctgcaa ttgttggtcc
    14521 ccaagttcct agtaaagctt gtccaattgc tgaacctact aaaccagcaa tgatgtttgc
    14581 gatgatcccc attgatgatc ctttattcgt gattgctcct gcaattgctc caatgatacc
    14641 gccgacgatt aatgcccaaa taaatcccat tttaaattcc tcctaactga cttcttactt
    14701 cttattgtac acgtggttcg ttattttctt tgactttttg tgcacctttg cctacagcag
    14761 attttgcttt atctgtttgg cgtgaagcaa attgtcctgt ggattttgct gcttctgtta
    14821 ctttgtcttg tactgtttct tgatcttttt ggtattcttc ttgtgttttg atgtctgcaa
    14881 cattcacatt cacttcgata acatctaaat gtgtcatatt gtttacttca gtactgatca
    14941 attctttgat ttggttgtaa atatcttcga tgtctttacc gtattctacg atcacatcta
    15001 gatccacagc tacttgtttc ttacctactt ctgtattgat acctgctgtt acgttatctg
    15061 tgttgactaa tttttcagcc atatttgaga aaaatccgcc atctaatgtc aatagaccat
    15121 ctacatcttt caatgcataa ccgatgattt tttggatgac tttgtcttca taagtcaatt
    15181 caccattcat catgcggttt tctccttttt catttgccaa aactgatcca tttgttgtat
    15241 tcatgttttt gttttccatc tttgtttcct cctatgattt aaaaaattga tcaactattc
    15301 ctgactgttt caaataaaaa ccgattcctg cgccaattgc tgtcatgatt atgatcaaca
    15361 atgtcttgaa aaatccaatc gttaaccata aaacagctag cagtagtcca agacccccaa
    15421 agataatagg gagcttgtat gctgaaaata gttctttcat tatttggccc tcctattcca
    15481 ctcgagagtg cttgtagtct cttgtatctt cttgttcttc ataaccgctg tatgtgactg
    15541 ccactttgac cgtttctttt gttccgagta ctttagttac ttcttcttcg atatcttgca
    15601 tcaatacacc tgttttccct actaatgaag aagttcgttt caagtctccg ttgacatgga
    15661 tatggattcg atttttcgtt gaacgtatcc gtactttagg tgaatgaatg aactcttctt
    15721 cgtgtaaatg ggaacgtacc aacccttcga tcgctttttt gtcgattgtt agtttgccat
    15781 cttcccgttt cataacgaaa gttcctcttg actttggata gaaaagaacg actagcaaga
    15841 tgataatagc aagaacggca aatactacag ctgcccagaa aatatattgt tgcatgtagt
    15901 aattcgttaa agtaaagaag cgaaatcgtt ccaattgttc aggcataata tacggcgcat
    15961 tgatcaacgc aatcgctaga aatactgaaa gtagcagtaa actcatgata acaccgatta
    16021 tttttaaccc cttattcatt ttccacctcc tataaactta tttttaccct gtaaataact
    16081 ctaccgacaa tcacagtata gatagcgaac agttagcata gcatcagtaa ataaagcgct
    16141 accaaacatt gctggatcat aacggcgttt tattgccagt ctgatactga aataacaatt
    16201 gcttacttat tctctattta cttttgattg ctggctatac ttaaaggata ttattcaaga
    16261 ttaaaaattg caaagattat gctcagttat tattacaaga ttctattt
//
LOCUS       DADVXE010000058        16257 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.059, whole genome shotgun sequence.
ACCESSION   DADVXE010000058 DADVXE010000000
VERSION     DADVXE010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.059"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            79..1506
                     /locus_tag="KB913_002110"
     CDS             79..1506
                     /locus_tag="KB913_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820451.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1598..1963)
                     /locus_tag="KB913_002111"
     CDS             complement(1598..1963)
                     /locus_tag="KB913_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBB6820452.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1960..2325)
                     /locus_tag="KB913_002112"
     CDS             complement(1960..2325)
                     /locus_tag="KB913_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBB6820453.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2517..2765)
                     /locus_tag="KB913_002113"
     CDS             complement(2517..2765)
                     /locus_tag="KB913_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820454.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2764..2892
                     /locus_tag="KB913_002114"
     CDS             2764..2892
                     /locus_tag="KB913_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBB6820455.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2949..4643
                     /locus_tag="KB913_002115"
     CDS             2949..4643
                     /locus_tag="KB913_002115"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBB6820456.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4647..4766
                     /locus_tag="KB913_002116"
                     /pseudo
     CDS             4647..4766
                     /locus_tag="KB913_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4743..4916
                     /locus_tag="KB913_002117"
     CDS             4743..4916
                     /locus_tag="KB913_002117"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820457.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            5294..6427
                     /locus_tag="KB913_002118"
     CDS             5294..6427
                     /locus_tag="KB913_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBB6820458.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6458..6778
                     /locus_tag="KB913_002119"
     CDS             6458..6778
                     /locus_tag="KB913_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBB6820459.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6807..7271)
                     /locus_tag="KB913_002120"
     CDS             complement(6807..7271)
                     /locus_tag="KB913_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6820460.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7403..8656)
                     /locus_tag="KB913_002121"
     CDS             complement(7403..8656)
                     /locus_tag="KB913_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6820461.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8685..9002)
                     /locus_tag="KB913_002122"
     CDS             complement(8685..9002)
                     /locus_tag="KB913_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6820462.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9028..9348)
                     /locus_tag="KB913_002123"
     CDS             complement(9028..9348)
                     /locus_tag="KB913_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6820463.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9812..11227)
                     /locus_tag="KB913_002124"
     CDS             complement(9812..11227)
                     /locus_tag="KB913_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6820464.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11244..12560)
                     /locus_tag="KB913_002125"
     CDS             complement(11244..12560)
                     /locus_tag="KB913_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6820465.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12710..13408)
                     /locus_tag="KB913_002126"
     CDS             complement(12710..13408)
                     /locus_tag="KB913_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBB6820466.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(13697..14653)
                     /locus_tag="KB913_002127"
     CDS             complement(13697..14653)
                     /locus_tag="KB913_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6820467.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(14766..15599)
                     /gene="msrA"
                     /locus_tag="KB913_002128"
     CDS             complement(14766..15599)
                     /gene="msrA"
                     /locus_tag="KB913_002128"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6820468.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(15774..>16257)
                     /locus_tag="KB913_002129"
     CDS             complement(15774..>16257)
                     /locus_tag="KB913_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820469.1"
                     /translation="VSSKKNFNQKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIA
                     SLENKEHIIKHEAKIGSQWVNLPYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEIN
                     HQPVKEQVNANGLVQISGVKGVADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR
                     "
BASE COUNT         5061 a         3277 c         2762 g         5157 t
ORIGIN      
        1 taactgatga tttcaaaaag aaaacatgtc ataatatttc ccatattgtg caaaaaaata
       61 caaggcggag gctctactat gattgaagaa tatattgaga aaaatatttt aagacagctg
      121 tttttatgtg ggcaattcta tgtaaataaa gaagtcaatc tagaaaagct ctccaatctc
      181 ctgcatgttt gcaaaaccac tttactcaat gatatcaata acataaaaaa agaatttgaa
      241 gaacagatcg cttatacaca tcgggaaaag gaccgttaca ctttatattt ttcagaacat
      301 atacctcgat gcaagatcat gcagcaattg tctcaaaatt cgttgttttt aaaaacttgt
      361 ctgctttatt tggaagaaga tgaacctgat tatcttcaat taactgaatg tgaattcatc
      421 tctgtcagca aagcttattc attaaaaaaa caagtattag cttattttaa tgactgcggg
      481 atcgaaatcg accgctactc ccctcgattc actgaaatgg aaagacgtct gctgcttctt
      541 aatgtgtcgt atcgtttagg cggttttaat tcttgggagc tacctgaatc gttttttgaa
      601 cgtgccgatc gtttcattga atccgtaacg gaaaatagtg gcagatttta tgataaagaa
      661 aataaagaaa tcttatcgat tggttttgct atcagtttcc tacgccagca agtgtgtgct
      721 gtgacaatag attcaaaatt tatcgaagaa atcaaaaaac gtcctattta caattatgtc
      781 gaatcagcat gggaaaacac tgatttccaa acctattata aaaaagaaga attcgccttt
      841 attttgacac tattcaatct ttgtaattat ggtttccatt cttatcagtt gattgcggaa
      901 gactttcaac agctacacca agtgtttatt gacaatactc ccgaaataaa agaactagtt
      961 gctacctttg aatctcactt caatcaagaa ttattcggaa accaaccgtt cgaacgtgcg
     1021 ctgattcatc tgatgcgttc ggcttgggat aactatcaat tattcatgcc agaaaaattt
     1081 tatcttttaa atgaggaaca gacaaattta tataaagaag tccagacaat tttttccagc
     1141 tggtccagcc agttacctta tgatctacgg ttgaatccta attgcatgcg ggcttttgtg
     1201 atcgaattga gcggaattct ccgtctgaca aaagaacatc tgactatcta tatcgtcaca
     1261 aattcggatg ttcattatct gatttatcgg gaagccttgg aagctgtaac tactttcgat
     1321 tttcaagttg caccaacaat ttattcaagt atatctgata taaagaagta tgcgcagcag
     1381 tcctcaaacc gggtattatg tgaacgtaca ttatatacac cagatgcggt ccaatatgaa
     1441 aatattattc ctatttcgat caatacgatc gatcgagcta tcatttcagc tgtgcaaaac
     1501 aaataagggg ctgtgacaaa aatcatgtca cagcctctta tttgttgaag atgcccattt
     1561 ctgtaacaat ctcttgatac acgtcaggct cacaacctca cttattttgg acatctacgg
     1621 gtccgatctc tttatttaaa aaataagaaa tgatggttcg gataactacc aacgccgcta
     1681 gttggaaaat atcctgcaag gtaggtttga taatcgattc gatgatccca gctgaaacaa
     1741 gaatttccaa acttagaagt atatagcctc ccaacatctt tttaatagca ttgttctcgc
     1801 tgactcggtc gctttgcact tttgtatgga caaataaata tttcaaaaaa tccttgattg
     1861 atagacaaac accccaaacc aataaacaga tagcaaagat atcaagtccc agtacaagtt
     1921 tttcgaaata tggaagaaga aactgcatca actctgtcgt catcctacct ctcctcttct
     1981 ttgtttttct ttgtcttcta tttcctgatt caagaaataa gaaatgactg ttcgaatgat
     2041 aataataagt gcaagcttca aaatatctgt ccaagtcggc ttgataactg actcgatgat
     2101 atcagcaacg actagtactt ccaagcttaa caaaatataa cttgctagca gttttcttgt
     2161 atctgcatta cgagtattac gttctgcata gtttttcttg acatgagacc aatcaaaaag
     2221 tttgaataga acaagaacga tcccgacaat taagataccg atagaacaaa tatttaaaat
     2281 agcaatgatc cattctagaa attcaattaa atttgagcga aacatatacg ctacctactt
     2341 tcttttaatt tgttcctatt cttttattgt aaaagaaagt taccttgttc gtctatttaa
     2401 aagttgttct aatgataacg gttcgcttaa atttttcttt ttcactctcc catttttctc
     2461 cctccatcca taaatcgtgg aagtatccaa aacaacgtag caagttaaaa taaggcttag
     2521 tccgtcatca gcttttcaaa gaagcactgt ctcggtgctt tttttgtacc caaatttcta
     2581 aaaatagaac catacacctc ctcaaatctt ttcttcttac ctaccctatt tttatttaca
     2641 ggaaaatcag acacttcttc ttttttgtca aaatttcctt tttcttctcg tcctatcatt
     2701 tggcattcta ataaaaacga actatccttg gatatagaaa gagaaaacaa ggaggcgttt
     2761 ttcatgagta aaaaattaat caaagtcggc atcggtttag gtttgcttgc ccttggcgct
     2821 gcatatctag gaaaaaagac aggactattc gaagatgaca gtcatttata tgatgaattc
     2881 gaatcaatct agcatcctat ttagttgaat cactacggac atacttggaa gacattggag
     2941 gaatcacaat gagaaaaagt aaagcaataa tgattggtgc cggtattgcc aatatggcag
     3001 cggctgttta tttgattcaa gaaggcaaat ggaaagggga tcagatcacc ttttattcat
     3061 tggatgatca cggttcaaat gatggtgcac cgaccgacac tgtagtggat gaatattgga
     3121 ataaaaacca tccattagaa aaccaaaaag gctatattgc tcgaggcggt cgcatgctta
     3181 attaccgtac ctatgtagat ttgatggatc tgttaagtcg aataccttct gttactgagc
     3241 cagggatgac tgctgaagaa gatacgagag attttgatgc aaaacaccga acctttgaca
     3301 aagcacgttt gatggaaggt ggcaaaggaa tcattgatgg cggaaaactg ggattcaata
     3361 ataaagaccg tattcttctg actaaactga ttgctatgcc tgattcagaa gaagaaaaac
     3421 tagacaatat cactatcgaa gaatatttca aagatgatcc acactttttt gaaacaaact
     3481 tctggtttat gtgggaaaca acatttgctt tcagaacacg tagttctgct caagaattgc
     3541 gtcgctatat gcatcaaatg atttatgaat tcactcaaat cgaacatcta gtgggcgtca
     3601 atcgaacacg ttacaatcaa tacgaaagta ttatgcttcc tttgatcgag tacttgaaag
     3661 aacaaggatg caaaatcatt ttgaaccgcc gtgtcactga ctgggaattc aaagaaacac
     3721 cgatgcaaga tgaaatcact gtgactggtt tgaaaattac caatacactg actcaagaag
     3781 aagaatacgt tgtggtcgat gaagatacag cagttatttt cactaatggg tccattacag
     3841 attcagctac tttaggagat tacgaaacac cagctgtaga aaatatggat tatggtgcag
     3901 cttctagtct ctggaaaaaa gccagtgaac gtttctacaa cttgggaaat cctgacaaat
     3961 tctttgctga tcgagatgca agcgaatggg tcagctttac cctgacgacg aaaaaccatt
     4021 tgttgttgaa tgaaatcacc cgtatcacga ctcaagaacc aggaaatgcc ttgaattcat
     4081 ttatttcaac cacaccgatc acgccgttag gccaaaaaga tgtcaatatg tctattgtcg
     4141 tgcatcatca accgcatttt acgtctcaga aaccaaatga aacagttatt tggggttatt
     4201 tcctttatcc aagacgacgt ggcgaatttg tggataaaca gtatattaaa atgaatggaa
     4261 aagaaatgct agaagaactg attggacaac tttcaaaagt agatcctgga ccagtgaata
     4321 ttcgtgaaaa agaaacagaa attttcgaca gcgtaataaa taatatccct gtctatatgc
     4381 cttatgcttc cgcgttgttc aataatcgtg ccaaaagcga tcgaccaaaa gtcattccta
     4441 aacattcgac caatctggcc tttacaggag aatttgtcga gcagccttat cagatgatct
     4501 ttactgaaca aagtgctgta cgttctggag aaatcgctgc tttccatttt gcgggtattc
     4561 ctatgtcccg tcttgtcaaa acaccgcgtt acgacaaaga tattcctact ctagctcgtg
     4621 ccgcaaaaaa aatgtttgaa taatcaagag gttgtgaaaa agctgccctg catcaagtaa
     4681 taagaacaac caggctaaaa cagcttctta tgtttttgat ttggttggac ttattaccgc
     4741 agatgcaagc ttttgaacac cgtttaccaa gaggttatga aaaagctgcc ctgcatcaag
     4801 taataagagc agccaagcta aaacagcttc ttatgttttt gacttggtta gacttattac
     4861 cgcagatgca agcttttgaa caccgtttac caagaggtta tgaaaaaggc gtttagtttc
     4921 gagtatgaag aaaaattttg tgaaaatggt tcctcacgtt tttgcataaa tttgacttaa
     4981 taccgagaaa ctgatccctt ctgtcataac ctctttttat ttatgtctgt ttctttttga
     5041 aaacaactat tttttcaacg tttactctct tgccaatcca acatcatcta acggatacaa
     5101 ctatttcaat gattaccatt acactaaaaa atcggaaaca cacctctccg aacacaaata
     5161 cataagacta tagaatgttt catttaagaa aaaaagcgtt tcattatcaa aaaggtaaga
     5221 tctcctttaa aatgaaatta tctgtagtac taataatgca gacaatttta tgaatctgaa
     5281 aggagcatct ccaatgaaag cagtcacttg gcaaggaaaa cagaaaatgg aaatcagaaa
     5341 cgtagatgat ccaaaaatat tagaaccaac agatgcaatc atccgtatca cagcaacagc
     5401 catttgcggc tccgatctgc atctttacca tcatggtgaa gcagttttgg aaaaagggta
     5461 tgttgtagga cacgaaccaa tgggaatcgt tgaagaagtg ggatctcaag ttcaaacatt
     5521 gaaaaaaggg caacgtgtgg ttatcccttt taatattagt tgtggtcatt gtcatttctg
     5581 cctgaatcac atggaaagcc aatgtgatga atcaaatcca gatcagttat atggcgggct
     5641 tttcggattt ggcaagttga acggtaatca ttggggtggt caagcggaat atctaagagt
     5701 tccttatgca gactctactt catttgttgt accagataat gatcttcctg atgaaaaagt
     5761 tttatttcta tcagatattt tgcccacagc ttattggagc gttgaaaacg caggagtaaa
     5821 aaaaggcgat acagttgtga ttctaggttc tggtccagtc ggtctattcg ctcaaaaatt
     5881 cgctgttatg gctggagcag agcgcgtaat cgcagtagat ccagtacagc accgtctaga
     5941 taaagcggct aattacaatg gggttgaaac ttatttctta gaagacacgg cacaagctgg
     6001 aacagaattg tatgaactgg ctaaaggtgg cgcagatgtc attatcgatt gtgtaggaat
     6061 ggacggatta gagcctgtca aagaaaaagc gaaaaattta gtaagcttac aaagcggcac
     6121 aatctctcca ttacagatgg catcgcaagc tgtcaaaaaa tttggaacag tccaagtaac
     6181 tggtgtttat atgactccag cttcttctta cccgctgcaa gaatttttta tgcgggatat
     6241 cgctgtcaag catggacagg caccaattat ccatctaatg ccaaaaattt acgcaatgat
     6301 tgcagaagga ctattcgatc ctacacaaat cattactcat tcgctgccac tatcagaagc
     6361 agcacaagca tatgagatct ttgacaaaaa agaagataaa aatataaaag ttgttttgaa
     6421 accttgaatt cagtaaaaaa tacaggtgat tttctttatg cccaaaatca aacgaaatac
     6481 ccatgagatc gaaataggaa aagaagaaga tatcgaaata cgaggacgtc gcttccgctt
     6541 ctatttccaa aatcgttaca cattgatctc actggctgtc gatttattaa ccgggatttt
     6601 ctatattttt ggaagccttg cttccttaac taaaatcccc gatcgatatg gcacctattt
     6661 ttatttggct ggtgctattt tcttgacgat tcgtcctatt ctcagaatcg taaggaacat
     6721 ttttatttac gacgaaaaaa aagcaatgaa gagaacaagc aaaaaaaaag aggcatgaga
     6781 atttttcaaa tctcatgcct cttttttcac cctatcgtat cactttgata cagacgagcg
     6841 gtcgtcccac tttcttcctt gaccattgtc aaaaatgtcc actcgtatcg ttcataaaac
     6901 gtggtatgat ctgtaattaa gtaaagtttt tcgtacccaa gttgatgcat ttcttttctg
     6961 atttccgcta atatccgctt ggctatcccc tgcttacgct tttccggttc aacaaacagg
     7021 gcacaaagat ttggtgtcag atcagggcgg ttatggaagt cgttttcaat gacgcccgct
     7081 cctccgacga tggtttcttt ttcatctaag accacatacc attgaggaat actttcctta
     7141 ttagcgattc cagtacgaat actttcctca tacacaacag caggaactcc ccattttgat
     7201 gaaaaccaat tcgcgctttg ttttactaat tctgggtgtt ctcttaattt gatccagtta
     7261 tatgtaacca atgtttaaac ctccgactaa aataaaacgt ttacaaaaat tatacaagtc
     7321 tttatgaaaa ttagcaatga caacaatagt gatgtaaaaa aaaaaacgga aaacaatcac
     7381 ttgttctccg ttttttgatt aatcaagcat ctaaagcttc ttttcttctt tcttggatcg
     7441 tagctacctt gacgaacggt agatagatca aaatagaaag aaccaaattg acagcggcta
     7501 gtacaccacc tgcaatactt tttgttgcca atacaccgcc aataattggt ggagttaccc
     7561 atggaggcat aacggtagct gctggcacta aacctgtaga agtcgcaaag taagcaacac
     7621 taactaagac cattggtgtc aaaataaatg gaatgaacat gatcgggttc aacacgatag
     7681 gtaacccaaa catcgttggt tcattaatat tgaagacacc tggcgcaatc gacaagtttg
     7741 ttacaaccat atatggtttg tttttacgtc ctactaaata aatagctaac agtaaaccta
     7801 aagttgcacc tgttcctcct aagttgacaa agctgtcaaa gaaaggtttg ttcacgataa
     7861 acggtgcgct atgtccagct gcgattgcat taacgtttgc ttcaatggct ggcgcattga
     7921 ttgtttgcat caaaggatcg accatattcg ctccgtgtaa accaaagaac cataagaatg
     7981 gtgtgataaa tgcaagcagt aaggcagatg gataagagtt tgcaagtccc ataaatggtt
     8041 cttggaccac tgtatagaaa gaacctacga tatcatcaac accgaatgca gcaaaaattg
     8101 cagcaactaa agcaaacgca gagatagtga tcattgctgg tagtaatgaa gcaaatgctt
     8161 ttgcaactgc cggtggcaca ccatcaggca ttttgatgat caatttttca tttccgctta
     8221 aacgtacaaa gatttctgtt gaaataatcc caacaataat agcaataaac aaaccgtttg
     8281 agctcatacc taatgctccg cctaaagcga agaaagagcc taaagaaatc acacctgcgg
     8341 aaacaccgtc ttttcggtag ccgttagcta aatgataagc aagcaagaaa gcaatcaaga
     8401 cagaaagaat ggcaaatgta ccgttccaag cagcagcccc gaatcctttc catgattcac
     8461 caccaaaaat tgagttcatc aattcttgga acccgggaat cggtaagtta ttgatcatta
     8521 ctgctaatgc tcctaagatc attaacggca tactcaccat aaatgagtcc cgaatcgcaa
     8581 ctaaatgccg ttgtgcacca atttttgatg ctacaggtat aaaatgtttc tccataaatg
     8641 caacaaattt atccataaat cttccctctt ttctttactg tagattacgc gttcaatcga
     8701 cgatacagat caatgatctc ttttgctaaa tctgtaaaag ctatagatgt catcagatga
     8761 tcttgactgt ggaccgtcaa aagcgtgact tcaacgtgat ttccttgtgc ttcttgtgtc
     8821 agcatctctg tttgagagtg atgtgcttgg actaaagatt cctctgcatc tttgattttt
     8881 tcatctgcta aagtgaaatc accttttttc gcagcagcaa tcgcttccat tgcatcgctt
     8941 tttgcatttc cgccaaacat gatcagaccc atgatggctt ctagattttt ttgatcttcc
     9001 atttattgta tcctccgata atttttatta tttgtttatt agtttttctg cttggtcgag
     9061 tactttttca ccattcatca tgccatagtc agccatattg attacatcta aaggaatgcc
     9121 tttaggtgct agcttttcag caaattgatt ttgcataaag cgtacttgcg gtcctaaaag
     9181 taaaacgtct acatttttag attctagttg attatccgca tctgaagcag atacagcaaa
     9241 gatgtctgct tccattcctt ttgcttctgc tgccttttgc atttttgtga ctaggagact
     9301 tgtactcatt ccagctgaac atacaagcat gattgttttc ttttccattt taaacacgtt
     9361 cctttctata cttacacttg tatataagca agtagcgtgc caactttaaa agcgctttaa
     9421 aaagttgata tcatcacatt taaggtctat accaagttgc atacacacta aaaaagaaag
     9481 cgcacactaa acacacaaat taatttttat tacctttttt cttttaacgt gcacaaaaaa
     9541 agttgtgaca caaaacttgt cacaactttt ttcaaataaa cggtattcaa aagcttgcat
     9601 ctgcggtaat aagtccaacc aagttaaaaa cataagatgt tgtttttact ttgctattct
     9661 tattacttga tgcaggacag ctttttcaca acctctcaat aaacggtgtt caatcagctg
     9721 accctgggta ttagctcaaa acgctggatt cacaacctct tttatttcaa ataaccagta
     9781 aatacaatga acatctacaa aaaacttcta tttatttata gatttcgtca ggcaaatcca
     9841 attctctctt atcaatcaaa gtctgatacc acgaagcaga ttttttcaat gttctgcttc
     9901 gttcatcgtt caattcgatt cgaactaatc catatcgatt cttaaatgca ttcattggtg
     9961 acacacagtc agtgaatgcc cataacatat agccttcgca atttgcgcct tcttctgttg
    10021 ctttgatcaa gtaatgcaaa tgctgtccga taaattcgat acggtaatca tcttgcacga
    10081 ttcctttctc atccatatac tgttcttcat attctcttcc cataccgttt tctgttatca
    10141 gccaagggat attatgataa ttttctttta gatacatggc tatatcatac atgattttcg
    10201 gatagatttc ccatcccctg gaattattca ttttcttccc aggtaaatca aagacttcat
    10261 aatatcgttc aggatggaaa ggtgtctctt cattccattg ataacgaggg gcgcgaacgc
    10321 gtttaggata atattgattg attccaagga aatctactgt atgatgctga atcgtttcta
    10381 aatcctctgt tgcaggatcg aaataaatcg attgtttttg acacaactcc aggaactctt
    10441 ctgtgtagta tccttttacc atcggatcaa aaaatactcg attataaaac aaatcataca
    10501 tataagcagc tttttggtct tctggagaat tggatcgagc atagaccatt tcaggattta
    10561 aaatacagcc aatccttcca ccataatttc cgctgcggta aatctctact gctttagccg
    10621 ttgctaaaac tttatgataa ttccacatca tccacttttt tgtgttttgt tcatgcggcc
    10681 agcgaacagc atccaaatag caacgcgttt ggggaacgat tggttcgttg aatgtaaacc
    10741 agttttttac cctatcaccg taacgatcaa aggcaatttg agcatactta gcataaaaat
    10801 caactacttt tcttgaagac cagccatcat atttttccaa aagaaaagct gggacttcat
    10861 aatgttccaa acaaatcatc ggttctacgt ctgcttcgat caaagagtcg atcatttcac
    10921 ttatatgctg agcatattct tcatctacta tacagttctc ataatcagta aaaaaacgag
    10981 cccaattgat agaagtccga taatgtgtca gatggatgga tttcatcaga tccacatcct
    11041 gctggtattg ttccataaaa ttagttgcta cggctgggcc atacccatta tgccaaacaa
    11101 aatgttcatt tttataccag ctatctataa acgaatcctg tccttctttt tttcctttcc
    11161 aaccttccgt ttgccaagca gaagatgcag caccaagaat aaaatttttt ggaatagtaa
    11221 ttttcatgat ttcctcctgt tttttagatc ccatcatttt ccacacgatt tgctactttt
    11281 acaaatggca gatagatcaa aatagaaaca ataatacaaa caagttgcgt aataactgca
    11341 ccgatatttc ctgctgttgc cagataagca ttgacgatcg gcggcattgg ccaagggacc
    11401 attacaactg ctttcgccgc aaatcctaaa gcggttgcaa aataaccaat cgttccagtg
    11461 ataagaggcg ttaagataaa cggaatagct aaaattggat tcagcatgat cggcatacca
    11521 aaaataactg gttcattgat gttgaagatc ccaggagcaa gggataactt ggtgatttgt
    11581 ttcatatctt cccgttttcc aactaacaat actgcaatca gtaaaccgat cgtgactcca
    11641 gacccgccca tactcatata catatcccaa aatggcatag taataatgtt cggtacttct
    11701 tttccagctt caaaagcttc cgtatttaca gcaattgccg ctaaaagcaa cggttcccgt
    11761 atcggcttca ccatttgatt tccatggata ccaatcaccc aaaagacttg cgcaataaac
    11821 atcaatagca aaatacccgg taacccttgt acgacacctt ctaatgggcg ttgtacgaca
    11881 ttgtaaatga tatcataaag gtacattcct gtaagttctt tgatgataaa tcccgcagcc
    11941 gcgatacccg atacagtcag aatcgtcggg aataaagcag aaaaactagc agaaacattc
    12001 gttggcacgg tatcaggcat tctcagctgt agtttcttct gtttcctcaa ccagcaataa
    12061 agttcaatag aaaggatgga gaccaacatt cccaaaaata accctttcgt atctgtatat
    12121 tgtttagcca atacgttttc tactataaca gtctgatttt cattcactaa ttcataaaca
    12181 gttggattaa cagataaata agacatcact gcgatgatac cagggaatac accatccact
    12241 ttattcagct tggctaattc gatccctatc agaaaaacag catagatggt caagaaactt
    12301 agtgtgacat agctgatggc agatgcgata ggctttaatt cttctaaaaa acgcaagaaa
    12361 cttatctgtg ctaagccatt ttccgagtca aagaccattg ctgaaaacaa tgtgccaaaa
    12421 gcacccgtaa taattaccgg aatcaatgca gcaaatgcgt tttttatcac catgatatac
    12481 cttaaattat tgattctcgt tgccacgttc cctaaaacat tggctaattt atccataaaa
    12541 ctcattccag atcccctcat tcctgcttct tctccttgac gtcatctctt tttgtctatt
    12601 agtcagcgct tacatttcga tgaacagaaa ctatttactc ctctttttta ccaaatataa
    12661 aacaaaaatt catctgatgt atttatcata aaatacatca gatgaactgt caattagttt
    12721 ctttttctcc tattattttc tgtaattctc tccgatttat tgccatatgg acagtcattg
    12781 catcaaacgc agcaagtgca ttccgccttt cgatggcctg aacgatctct gtatgaatat
    12841 cgatcgtctc gattttcaga tgctggatat cataattttt attaaacaaa gcaattgatt
    12901 cattaatgat tgggataata tgcagcaagg ctacgtttcc gctagcttct gcaatcatcg
    12961 tatgaaaatc gatgtctaat tgaacatgtt cttgtgtgcc ttctcgaaaa gaagtttcaa
    13021 tcttttgcgt taattttttc atttggacga tttgattctt cgttgcatat tccgctgcca
    13081 aacctgccat cttaggctcc aataaatatc tcagttcaaa taagtctcgt atcatccgat
    13141 cctgatcttc aatcaaagaa aaaccgagtg ggtcattggc aatccctcgc ttatcactga
    13201 caaatgtccc cgctccttgc cgaacttcaa ggatattcct ggaagctaga gcccgcacag
    13261 cttctcgcac cgtgcttcgc cccacctcta aataatcgga caattcatat tcattcggca
    13321 gtttatctcc tacttgcaac tgcatttcct ttaaatatct aaggatcttg tcagtagtta
    13381 cttctactag ggttttattt tcttccaaac cacatacctc cttttcatct gatgtatttt
    13441 ttcgtaatta ttataacacg tttgaatcat ctgatgattt tttgtataca aaattgatta
    13501 atccgttcat agacatacaa acgaagaaga tatttaccat aaaaaagact aggataaaat
    13561 tcactcctag ccttcgatca tttttatttt gaacgacaaa aaatatgatg ttcaataaca
    13621 gacgatcttc attcgattct tgatgtcatc ttttgttttt tttaatatat ggataaaaag
    13681 tttgattaca tcgtttctat tctagaattt ggtcgattct caattcttct tctggtgaga
    13741 aatctaaatt atccatcatt cgaacacttt cttgtaactg acttaaccga cttgctccga
    13801 ccagtacact tgtaacagat ttttgtcgca aattccatgc aagggccatt tgcgctaatg
    13861 attgtcctcg tgatacggcg attgtttgca gtgctttgat tttttccaga gttgatccaa
    13921 cttgttcttc tgaaaggaat ggtatttcct tacgatgtgc tctagaatct tcaggaatac
    13981 catgtagata acgatttgtc agcaaccctt gagcaagcgg actgaacgtg attgccccta
    14041 gcccttcttc ttctaatact ggagatagat cgtcttctag tagtgcacga gaaaacatat
    14101 tgtagcgcat ctgatgaata atgaacggtg cttcctttct ttttaaaatt tcagtcattt
    14161 tttttgtatc ttctccatta tagttggata taccaatata taatgctttt ccttgtctta
    14221 caagttgcat caaagcttct gctgtttctt ccaaaggtgt atcagggtct gggcgatgat
    14281 gatagaagat gtcaacataa tctagcccca ttctttggag actttggtca caacttgaaa
    14341 tgatggattt acgagagccc cattccccat atggcccttc ccacatatga taacctgctt
    14401 tgctagaaat aatcagttca tcacggtagg cttgaaaatc ttctctaaaa atacgcccaa
    14461 agtttttctc tgcagctcca gcagggcctc cataattatt cgcaaggtcg aaatgggtaa
    14521 ttcccatgtc gaatgcgcct cttaaaatct ctctttgatt atggatagga tcataatcac
    14581 caaaattttg ccataatccg agagataaaa tcggtaattt caaacctgaa tgaccggatt
    14641 tacgatattc cattttttca taacgtgcac tatctgcaat atacaatttt tctcctcctc
    14701 atcaaatctt tttaaaacgc tttctttttt ctatttttag tttactacat tttaaagaaa
    14761 aggagttaat caaaatgatt ttttcgtata tttttttgcc atttgttttt tactcgttga
    14821 tagatcagaa attgattacg tgcttgctgg atttttttat aacgtttcgg ttgttttttg
    14881 taaaattgct gatgatagtt ttctgctggc caaaacgtac cggctggttc gatttttgtg
    14941 acgattggtt ggtggaaagt tcctgaactg tctagtttct gttttgattg ttccgctaat
    15001 tctttttgtc gttcgacttg ataaaaaatc actggacgat attgcttccc tctatcttga
    15061 aattgtccaa atgtatctgt gggatcagta atttgccaat agattgtcag caactcgcta
    15121 taacttattt ctcttgtgtc ataaatgatc tccacagctt ccacatgacc tgtgtaacca
    15181 ccacttactt gatcataatt tggtttttca acatgtccgc ccgtgtatcc tgacaaaaca
    15241 gataggatcc cttttttcga ttcaaacggc tcgaccatac accagaaaca tccccctgca
    15301 aatactgcac gttcttgata gtcagcatct tgcatggcat gcttggaaaa gtcatatttt
    15361 tgctccttat caaatccttc cgtaatcaat aaataaaagt ccattacatc aggcgtcaga
    15421 ttcattcgga tagctaatgg acgtagtgtt gcttctagtt ttgataactg ttctttaacg
    15481 gatatatttt ctcttatgtc attctttgtc tgaatcaata cttttcgttc ccaatctcgt
    15541 gtattcggat tcaaaatcag attataaagt gtttgaatga atatttgttc ctcatccata
    15601 gattctcctc ctttccgaag aagacaagct agtgacttta gctgtaattt atcataaagt
    15661 gaggaaataa gcgattactt catcccccta cagatttttc gtataaaaaa gagagaatcc
    15721 ttatcgacag attctccttt ttaatcaatt tattttataa atgaaaagtt aatttacctt
    15781 ttatggaaaa ctattttaaa aaataaacat aaatatgcag ttaatgtaac aagataagaa
    15841 ataatagtcg ttactgtata acttgtgctt actttaatat cagcaactcc tttgactccg
    15901 cttatttgta ccaatccatt agcattcacc tgctccttta caggttgatg atttatttct
    15961 acattcgttc ctaaataagc atatacagga agtgtgatta cttggctctt ctcattagtt
    16021 actctatata tgatagaact accagttgtt ttataaggaa ggtttaccca ttgactgcca
    16081 atctttgctt cgtgttttat tatatgctcc ttattctcca atgaagcgat aggagaataa
    16141 tcatataaaa aataatccat tcctttagtg gtatacgcct ctactgtttc tttgtttaca
    16201 acaatatgtc ccggctgaga aattattttt tgattgaaat tttttttact agaaaca
//
LOCUS       DADVXE010000059        16178 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.060, whole genome shotgun sequence.
ACCESSION   DADVXE010000059 DADVXE010000000
VERSION     DADVXE010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16178
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.060"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            395..1834
                     /locus_tag="KB913_002130"
     CDS             395..1834
                     /locus_tag="KB913_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6820470.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            2129..2347
                     /locus_tag="KB913_002131"
                     /pseudo
     CDS             2129..2347
                     /locus_tag="KB913_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2596..2811
                     /locus_tag="KB913_002132"
     CDS             2596..2811
                     /locus_tag="KB913_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820471.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(3028..3284)
                     /locus_tag="KB913_002133"
                     /pseudo
     CDS             complement(3028..3284)
                     /locus_tag="KB913_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3471..4382)
                     /locus_tag="KB913_002134"
     CDS             complement(3471..4382)
                     /locus_tag="KB913_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6820472.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(4401..5405)
                     /locus_tag="KB913_002135"
     CDS             complement(4401..5405)
                     /locus_tag="KB913_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBB6820473.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(5402..7525)
                     /locus_tag="KB913_002136"
     CDS             complement(5402..7525)
                     /locus_tag="KB913_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6820474.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(7530..9977)
                     /locus_tag="KB913_002137"
     CDS             complement(7530..9977)
                     /locus_tag="KB913_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6820475.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(9964..10353)
                     /locus_tag="KB913_002138"
     CDS             complement(9964..10353)
                     /locus_tag="KB913_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6820476.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(10413..10916)
                     /locus_tag="KB913_002139"
     CDS             complement(10413..10916)
                     /locus_tag="KB913_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBB6820477.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(10929..11153)
                     /locus_tag="KB913_002140"
     CDS             complement(10929..11153)
                     /locus_tag="KB913_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820478.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(11257..13167)
                     /gene="ltrA"
                     /locus_tag="KB913_002141"
     CDS             complement(11257..13167)
                     /gene="ltrA"
                     /locus_tag="KB913_002141"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBB6820479.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(13913..14050)
                     /locus_tag="KB913_002142"
     CDS             complement(13913..14050)
                     /locus_tag="KB913_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBB6820480.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(14047..15231)
                     /locus_tag="KB913_002143"
     CDS             complement(14047..15231)
                     /locus_tag="KB913_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBB6820481.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(15490..15780)
                     /locus_tag="KB913_002144"
     CDS             complement(15490..15780)
                     /locus_tag="KB913_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820482.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(15770..>16178)
                     /locus_tag="KB913_002145"
     CDS             complement(15770..>16178)
                     /locus_tag="KB913_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBB6820483.1"
                     /translation="RVYEVTGTAPTLSTKQGGTKIMIRKNETEYQEVKPEDSVNLAFP
                     NSTSRRGRLGKQSVHTLLTGDQQAIVTDQYQIRKLTPRECWRLQGFPDWAFDRDSQVN
                     SDSQLYKQAGNSVTVPVIFDIARRLKELDVHGL"
BASE COUNT         4556 a         3443 c         2818 g         5361 t
ORIGIN      
        1 actattgata tttagtataa tcctatggaa ttgaatatca tagcaatgta tttgaaaagc
       61 aaattggaaa acaaataggt gcaacaccat aaatatgaaa aaattgggaa aaagtagaat
      121 ggaaatttgc ttacgtctca cgagatagct cacactatta atctgaagaa caatgaagtc
      181 gacttttaga aattgctaga agaaagtaaa gcgaattatc actagttact atagagtaag
      241 ttcaaataaa gcatctccaa cttacatggt tacatgagga tatcaaatcg aaattactca
      301 agcttcctat ggctagagtc gcgagaagtt gttgggcagt agacataggt tatattgttc
      361 ttagctacac gatcattaga aaggaaatcc tattatgtat agttatcaag aagatgcaaa
      421 agtccaaaaa aatcgctggt ggattttgat tgctatatct atgtttacct tcatgtccac
      481 attggatggc agtattgtca atattgcact acctaccatc tcagatgata tgggcatacc
      541 aatgaatcaa gcggaatggg tagtgtccgt ttatctgatg attgtctgtt cttgtttgtt
      601 gctgtttggt aaaattggcg atagccgtgg gaaaatcaaa gtatttcgga ttggtacgct
      661 gatctttgtc ttgggatcgc tgttgtgtgg gttcaatcat tcgctaggta ttttattgtt
      721 cgcacgggtg gtacaagcca ttggtgctag tatgactatg gctacaaatg ccggaatcat
      781 cacggaagtc tttcccatac atgaacgtgg tcgggcattg ggagcaatag gtgcgtttgt
      841 ttcattaggc tcgattgctg gaccaggtct tggcggcttg attttgtccc aattttcttg
      901 ggcgtacatt ttttggatca atgtaccggt gggaatcgta acgatgttga ttgctgaaaa
      961 attcttacca aaagatatca ccatgagcgg ccatacaatc gatggagggg gctttgctgc
     1021 cattgcggct acgattatca gcttttttgg agcaatcttt ttggggcaag aaagtggctt
     1081 tttccatcca gtcccccttg tactgttcgt aatttcagtg attgcctttg tcagcttttt
     1141 aaaagttgaa aagaaagcag cctctccatt gatttctttc ggtattttta agaacaagat
     1201 ttttaccatg agcttgatta cagccttgtt gattttttct tccaacttct ttgtcaatgt
     1261 agtgattcct ttttatctgc aaaatgctcg cgggttgagt cctagctatg ctgggctgtt
     1321 gatgatggtc tttcctttga tgatggtcgt cggggcgcct ttaagcggct acctgaccga
     1381 ccgggttggc ccggagattt tggtattagt aggcttgggc ttattgtcgg taacccaggt
     1441 catgtatatg tttttgtcag tggactctcc tttgtggcta tacattgtcg ctactgccat
     1501 catgggtgcc ggcaatgcct tgttccagtc ccccaataat acgatggtta tgagctcggt
     1561 cactatcgaa aacttgggac tggcaggctc gatgaattcc tttgcccgaa atttggggat
     1621 ggtcagcggg atttcgcttt ctacgacggt cttatatcaa gcgatgtctg ctaagatggg
     1681 ccagcaagta actaactata tcgcaaatcg gccggatgtc tttttatatg gaatgaagat
     1741 taccttttta ggcagctttg ttttgtgttt tgttgccttt ttcctgacta tctggcgtat
     1801 caaaaaacaa ggaggtattc agaaaaatgt ctgaaaaaac cactgttgaa gaatttttgg
     1861 aggcctgcgt atgggtgagt gggatttcca tggatgatgg aagatgaagt gaacttctaa
     1921 aagccgaaaa actcaagtat tatcttcaaa atactagtgc tcaatgagat gcttgatttg
     1981 atcacaagaa gactgcgaaa gccgctggca accgcaagct aggtatccca ccgatggact
     2041 acgttttaga ggctactggt tatgaatacg gagccaacgc tctcatctgc ataagaatac
     2101 atcacccaga ttatgtaaag attttcgata cttctgtcaa aaaatcatta agatagataa
     2161 atgatttccg tctagtcaaa ttggttcaga atgtagacac acagatggta agaagtcact
     2221 cacaattcga gaatggactt gtcctatttg ccgtatacat cataatcgaa acgtcaacga
     2281 tagtatcaat attttgacca agggctatga atacaagcat tgccttagaa aacatcaaga
     2341 accttaggaa caacggggat agcttggtta ataagagata ccgctgttta ggcttgcaag
     2401 tatactcttt tatcaagaat tccgtggctt tagtcatgag aggcttaata ctatgaaaat
     2461 tttctttagc atttttgatt taggttcctt ttctaattat aataagatga ccactacagt
     2521 aacctactga aatatataaa cagccactgt agtaccattt tcaaagtagt ctatgagagg
     2581 agaatcttca ttcttatgaa cgctggaatt gcggatatga atttaataaa aaaaaccctt
     2641 aatgatttta cttccaattc aatatcaaaa ggtactggta tcaatttaag cacaataaaa
     2701 aagctgaaaa gtggtgaaag atcagtggaa aagctgaatc ttttagatgc tataaaaata
     2761 acggaatttg ctatgaaaaa tggaaaagct gagattgaaa tatggagata attatcgtct
     2821 agtgaattac ttgccactta gctgaattta acgatccttg gtgcttgaag ggggagattc
     2881 ttgggaatag agcatacttg caagcctatg tctttactaa caacgatatc tcttattaac
     2941 caagctatcc ccgtagttct aaggctttta cttttatcta agcaataatc gtattcaaag
     3001 gaaatttttg acccttagaa agtctcattt tatcagacgt gagcttaggc attgctgaat
     3061 tttgttaatt cggttttagg ttgtgctttg agcataatat gaaagtattc tttatcacga
     3121 tttcattcat ctaaggtaat gtgatgtgat tctgaaattc tttcaaaggc agtttttgca
     3181 taagctgaca ttacatcatc aatgacatgt ttacaatgtt tcactactaa aataaggggg
     3241 taaccaagaa gaaaaactga atgattattt gtatctaatt ccatggtata tcaaccattt
     3301 cctatataga ctgattatga catggattaa aataaaaagg cactatgtct taattgtcgg
     3361 ttttcgagtt accgaatggc attcatcacc cacctataga ggatgggcga cttctgcctg
     3421 aaataagtta cactacttat aacttctaat aaaattagat tgagtcatta ttatttaaca
     3481 tcaacgattt tccagtttcc atttttttgt aatactaatt tgtactgaaa gtagctagtg
     3541 gtttttgata cattatcaag gtattttatc tttgtactca ctagaaaatt ttttccgttt
     3601 tgtagataaa ctggattctc taactccgaa aactttaagt caatattgat tggtcgcatc
     3661 gcaccatttt caacataata ctccaattct ttttcagaag ctgatggata aagtttaaaa
     3721 aatgtttcta aaaaatcggt gatttcttcc gttgttttgg catcaatttc tgaatcgttt
     3781 tctacttgtt ttgcttcata ttttgccttg tctggctttc caatcattgt tggcaaacta
     3841 gttactaaat gattcctgtt ttcatcttca aagattgtca ctcgatatgc agaagaaatt
     3901 gattgcgtct tttttccctc tgtaatatgt tgctccacta aaaatgaaac gacaaattct
     3961 tccgagtgtt tttcaacatc tagaattttt acagattgaa cttcggaact cgtgggaata
     4021 tctgctcgaa ccatatcttg gattaaagcg agaccgtttt ctgtaaggta ctgttcgaga
     4081 ttactcattc tcttttcaat tgcttctttg ttatttttcc atgaaaaata ttctttcgca
     4141 aaatcctctg taaaactttc aacgccagaa gtattcacta ccttctcttt tataaccact
     4201 ttttcatgag ttgtatgttg atcaatggcg gtgaaatttt tataaacgcc aaaagcaaga
     4261 ctacaagaca ataaaagcca aagggcaagc accatttttc gatgcttacc cacggataca
     4321 actcgttctt ttttcttttt tgggctcttt tccttttgat tccgttcaat ttttatcttc
     4381 attctttttc ctcttttctc ttatttgtat cggccagctc cgataagatg ctgccgccaa
     4441 tagttttccg ttagattcgt ccaccccact ggatctcctg catgaaacat gcgattctcc
     4501 cctgcgtaaa tgcccacatg ggtcacataa gtaccggcat cataggttga atgaaagaaa
     4561 actaaatcac ctggtttggc atcttttaga tcaatatgag tcatggcatc atattgatcc
     4621 tgagccaccc gaggaagttt caggtcaact ttggcataac accattgggt caagccacta
     4681 caatcaaacc ccgtttctgg acttgagcca ccaaacacat aggccgttcc ttcatactta
     4741 aatgcctcat caaaaatttc ttggactatt ttgtcatcaa actgagttgt agttaggtat
     4801 tgcttcacta ataaacagta aaacatattg ccataattat accgccaccc accattttcc
     4861 ttaatcgcga ttgggttggg gtaatcgact ttttgaccac ctgatttttc ctttgaaaaa
     4921 gattcagcta aagcaaaact atgcttcttc ccgtttttcc cgacatgatc tagatacccg
     4981 ccaccatagt tataggcctg aataatacta tcttgatcac accctagttc tttggaacgc
     5041 ttaaccaaag acgcaaaata gagacagcct tgtttgatgg atgcctcggt acttaatgaa
     5101 ttaggtggta atccggctga ctcagaactt tgcataacgt cttccattgt gccaccagat
     5161 tccacttgaa taatcgccaa aagaattgga atatactctg ttatatccga ttctttggca
     5221 tacttttcca ccattgcacg gtgtttcaat acttcttctg agacactagt tccgccagga
     5281 gaagtgccag aactaccatt tccctcactg tcttcaccaa acaacaaacc cacacacatc
     5341 aaaataccca taaaagagat ggtcagaaaa gttaatgaaa taacacccac tttcttcaag
     5401 ttcatttttt ctcacctgac cttgattttg gacgatggtt cattcttttt tgtacttttt
     5461 gattggtctg ctttggcaga gtggacctct gtttcacttg ttggaaagaa tttttcttac
     5521 ttgctgattg gcttttccct tttgaaatga tttcttgact agttagtttt cgtttgattt
     5581 cgggattcag atttgctctc acaatccgct ttggtgcttc ttttttcagc atcatatctt
     5641 tctgaggttg agctgcttta tctattggaa tattcgccct tctttttccc tgacgatttg
     5701 ttgcttcact cagtatcttg cgtttttcgt ccattttcgc atttcttcgt tgtcgttgtt
     5761 tttctcgcaa atccactcga tccgcttttt cttggaacag tccgcgcttg aattcttctg
     5821 gtgctttttt cgacttttcg attcctttat ggagattgta tttcaaattc gttggcgtat
     5881 tccttacctg atcctttact tgtttagtct tatctttcac caaagcttgg gtatccaaaa
     5941 ctttgccgat ttttctccca gccaaattca ttcgggattg tttcttatta tttgaaactg
     6001 gattctcctt agttaagtca gatagtattt cgtgatcgtt cggtaatcgt gaattctttc
     6061 gtagagaaga accggatggc ttaaatttgg attttgattg ttcctttgcc aacttatttc
     6121 cgactgctgc accaccacca aaagccaaag ctcgtcccac atttcgattg agttgccgca
     6181 attttcgatt cattaacatt tgcggttttc gcatgacgcg tcttcccatt gactggctat
     6241 cattactctg gaggttgaac atactcataa tgtcgcccaa tttgaaatag ataccggcaa
     6301 aggtcacaat ttgcagaaaa gcaaccatga aaaatggata ggttgccgaa atattgaaaa
     6361 acatcgtgga gatgctaaat gcagtcgtaa tcaccaaagt aacacccgct cgcatcataa
     6421 tcgtattgaa taaacgaata atcgccttct ttcctaaact ttcataagtc ggcaacatgg
     6481 acaataagaa actaattggc agaaacatcg caaagataat gaagagaatt tgcgagaaca
     6541 acataatccc tgttagaaga aaaacaaaga aggaaatgcc aatattgaac aataccaaaa
     6601 agaccacggt ccctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattgt
     6661 cttcaatctc tgccttgacc gcttcttccc gatctttgcc tttgttttca tctggactca
     6721 cagatagaat cttgttgacc cggtcttcac caatttcttc tatgttggaa tcatcaaatt
     6781 gcagtagtaa ccaaggttgt tggacttgaa tcgaaaacaa actatcccga atcaaatcca
     6841 cactatcttt tccttggctt tctgaattgg gtacaacgat ctcggttcca agggtaaggg
     6901 ccgcttcact aacatctgag ctaaagtcat tgatttttgt gatataggta ggcgcataag
     6961 caatgaacga acccgatagt agaaaaatca tcacaaaatt aatcacggct cgaactgctt
     7021 tcgtggtttc tcgttttaat aatccggtat acgccacata cacccccaga gctaaaatca
     7081 tcaataatag aaacccaaaa taaaatccgg aggtctggag tccattttca gtaataccag
     7141 ccaatgtttg gatattcttt ccaatacttt cagccgtatc cgaaatgaaa tctaatttgt
     7201 aagcctcttg aaccacataa cccgtggcgt tcgacaaata caaactcacc gtccaaatga
     7261 aattagtaat ggcataaaga ccatacatca cgcttttccc taagccatca ccccaattcc
     7321 aaggcaacca atcccaagag ctatccacaa agaaatctag ttgatagttg ttcagtgaat
     7381 atttggaata tagatttcct gcttcaactg tatcatcaac tagccctgtc gcctcggcta
     7441 ccgtaccaac taaactcaat agaactatca gagtgagtat gctaataaaa acgattccca
     7501 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac aggtggacgg
     7561 gtatcaaagg catggaagag ttcttcaaag actggatgta cctgaaccac gcctacccga
     7621 ccatacaaat cctgcatcaa gcattggcca ttttccaaat ctcgtaggcg tttttgattg
     7681 ctttcatctt ctcgatccaa gccaaagaat tccaaggttt tcttgatttc atgaatatcg
     7741 gtactgcgaa acgcaaactt caacccgata ttattcttca agcgttcatc cagtaaatca
     7801 tcactatttt gcgtgacaaa gtaaaccccg gcattcatag cccgcccagc acgaacgagc
     7861 ttattcgata atgttttccc ttgcgctact tgaagaaaac tccacgcctc atctaagtct
     7921 acaattttga agatttctcg attactatgg ataaagtcca aggcaaaagt ggaaatgacg
     7981 attagcatgg aaacactaag caattccatg gtggtatatt cttcaaaagt ggtttctgca
     8041 tctggtaaaa ccaaatccgc tacttgaatg atatttaact gcctatctaa actaatcgac
     8101 tgggtaatcg aaccatctga gaaaagcaaa tgggcaaaat cataatcggt aaaggactcg
     8161 atgtgatccg cgatattttc cgcaactggt gagccttctt ttcgaagctc attaattact
     8221 tgtaataatc cccgttgatt gctttgggta accgtccgaa tggccttacg caacactgga
     8281 aacttctccc catctcgact agaaattcct gttaaaaagg tcagaatatc aattgctaga
     8341 ctttcagaat ccttcttttt ctccataatc acataaggat caagtaatcc ttgatttttt
     8401 ggcttactag ttaagttgag aatattgatt tcatccgcaa tttctggcaa ggtttctttc
     8461 cagccacccc gttccccttt tggatcgaca atcacagctt gtccaccaaa aaggacggcg
     8521 taataaacta agagattgtt actaaaggac tttccgccac cgagtgaacc gaggaatgcc
     8581 gctgctagcg cattggtaac tgaatccttg accccttgtg aggccaatgc cggtttcagg
     8641 taaacattgc gccccgtatc tacgttataa ccaaagtaaa tgccttccaa ctcccctaac
     8701 atctgagtgg cgccaaaacc aagtccggcg agaaaatcag acgtaacata ctggatataa
     8761 tcattcatgt atcgcttact agaaggtaag aattcttcat gtagccccat catatcgcca
     8821 aaaggccgga ctagttttac attggtatca tcataaaaat ctagcacttc atcacaccgg
     8881 cgctttagtt catctactga ttcggcactt actcgaacca catagctcag tttgtacatg
     8941 gattctttgg actgatccaa ggtagtttcc aattcatcta cggaatccaa tgcatctaag
     9001 acattggaat ttgtttcatt gtcagattga taggcatggt tgtccaagtc ttttaattcc
     9061 tttttcttat tgcgaacggt agcaagtgcc tttttgttcg tcacaatctc cacattcata
     9121 ctagtgtcaa ttgggaatgt aaattgttgt tgctggtaat agaaaagttc tgaggaggga
     9181 aactccattt cccccacaat tgtattaatt gttaagtacg ctacatatga ttcatgattc
     9241 tcatgttcca tgcataagta ccggggcttt tcttcaatca aacaacgact gggacgtaat
     9301 aagtcgtaac gtttcaccaa agtttccgac ttcagctttt tctttggtag ctgaaattca
     9361 tattcttcaa atggtgtacc cttttcgcca tagatatgtt caatcaaata catcagatca
     9421 ctcggtgtga ctcgtctgac tttaaatctt cgagccaatt tactttccat tagtttttca
     9481 agcttggtat atcggcgaat ttcttcattg gataaggaaa caaaatcgcc catcaaatga
     9541 tgattcactc catagacaaa ttcttgaaag ccggagaaga aagatttctt gagattcttt
     9601 agattgacct cttcatctgt cgcaatcagt ttgaagccaa taaaaaagcg ataatcaatc
     9661 tgactatcgc caatcatgga tactaatgcc tctgtctgta aatcaattcg ttgtttcgct
     9721 acttctgtta atcgcccggt aatttccttt tttgatcgtt cttgcgtggc acgaatacta
     9781 ctttctgtgg caatttgtaa ggcatgaatc ttgccttcac gattttgcgc aatcaattga
     9841 cgaaagttat cgtggacttg atatttctgt tcaggtgaca aaaaggagta attgtaaggt
     9901 attaactcat agtaggcaaa acattctccc tcttgattaa agacaagatt attttcaata
     9961 tacttaatcg ggtacatagt tcacactcct taccagagta atgggttcgt cccatcgttt
    10021 cttctgttct ttgactttct ttcctgcgaa agtgacctta aatcgtaagt gatagctaat
    10081 aaaagatcgt aaaaatccca atggtttctt accgtcaaac gttttttgcg acatgaacca
    10141 agtaactgcc accggtatac ctaagtattt taaaaaggcc ccctctatca tagatagtgg
    10201 aggcacatgg gcaaatacga tgacaaacag caaggataaa acaaaccaag ccatctggtt
    10261 aaaagtcaca ggaaaaggca gttgaaagtc attaattgca taaatgacct tttcaactgc
    10321 ccaaatactg gtgtagcttt ttattttctt catcaaatca ttcctttaaa aagaaggata
    10381 gtttagaaat caactaccct tcaataattt tgttaatatg gatactcaaa aacacctcga
    10441 ctcgttacca aataattgcc tccaatctcc aagtctctac cacacgcatc aaaatcaata
    10501 tacgtcttca agtgttctgg tacttctcca aaatcaccag cttctacaat caagaaatat
    10561 gctacatcac tcatatcatc gcaatctgga taatagataa tatcatccac atgctctacc
    10621 atctcctcaa aagaattgaa gaaagcatgt tgaatctcag aagcaacttc accaactggc
    10681 gttccttcaa gttcctccgc taagccacac aaccgattaa tttcctcaat tggcgtatac
    10741 tcatcaatct caaagggaag ttcataatca tgaattgcat attcctcgta ttcgtcattt
    10801 aacccaattc gttctttcac ttcatcaaaa tcgacaggtg gggtaaacca cgcccccacc
    10861 aattcacctt cgttatattt cccgaggttc gcaatataaa cacgcatctg ttccatcgtg
    10921 cttccccctt acgcaccgac aattcggtta aacaaactga gtaagacatc cttcacccca
    10981 gaagcattaa agaccaatcc gaccgcaatc aaagcaatca ccaaaaagcc aatcagtttg
    11041 gaaaactccc gcttaaatcc taaaaacaaa ccaatgacca caattgccag taagactaag
    11101 gattgggcat tggttaaaaa ccattgatat atggataggt aagttcctga tattataaat
    11161 atctcaaact tttcccccca ttcacacgga gcgtgcgact ttcaccgcac tccgcgttcc
    11221 atcgtgttta tattgaaaag tatttatgta gtagacctat atcaagttta attcttgatt
    11281 gccagctaat actctatatt tatttagtct tatgagctgg actttattta gcttcaatag
    11341 agctatatat ttttgtattg tttcttctgt tttagcgtgt attagacggt gtaccgcctc
    11401 ttttaccaaa ataagatttt tataatcgtc atttccacca gctccagttg gtacaatatg
    11461 atgacaatgt atttcattag cttgttgaaa ttcttccaga gttatagcac attttccatg
    11521 ttgagcagaa aatagcgaaa ttcgattgtc tgcgtattct attgtgcgat tttccaaaga
    11581 taatttcatt aactggtaca tcagtaattt atcaacactt agattggtgt ggataaattt
    11641 tcttccctct agagtgtagc aattcgctaa atacaccttt gccattggtt ttctgtgttg
    11701 gatatatcca acagggaaaa taggttcgcc ctcgccagca acataccgaa gcattttaga
    11761 tttaccatat cttgttgcct cctttgtcgt aagttgtctg cctgtttttc tcaatctgcc
    11821 ccttttgttt gtacctaatc tgttagtgaa gatagccatt acagctctat tcagtttcat
    11881 acaatccaga tttacattcg ttgcaatctg ataataattt tgcataccta ataccattga
    11941 attataaagt cttgtttctt ctaattccgt tttccctttt gagggagaag caattttctt
    12001 tgcctgtgat accagcttgt ctttttggtt tttgaattgt ttatcactta tatgtgattt
    12061 aacaactaac ttctttcttc tcggtatcat tttaatcttg aaaccaagaa agtcggagta
    12121 tctttttcta acatttacaa ttcttgtttt ttcttgtgat acttccaatt ttaatcgttg
    12181 ttcaatccat tgagtgattg ctattttggc tttttcagca ctttccttgt agcggcagaa
    12241 aactctaaaa tcatctgcat aacgaaccat atacatttcc tttaactttg ttttcttcat
    12301 ttctttgtaa gcgttgcttt tacatgggct accgctttta ttgatatgaa ccacatagtt
    12361 ttttgtaaca ggattttcct gccattggct ttctacccaa tggtctaact cattaagaac
    12421 aatgtttgct agtagtgggg atattattcc cccttgcgga gttcctttct ctggatatgt
    12481 tattgtaccg ttagtcattt tgattggagc ttttaatatc ctttttaaaa tgaatatcaa
    12541 gtgcttgtcc cgtattccca tagcccatat ctgttttatc agcttggaat ggttcacgtt
    12601 gtcaaagaaa cccttaatat caaattcaat cacataatgt agctggctga tttgtaggcg
    12661 gttataggtt gcttttattg cattttcaac tgacctatta ggtctaaaac catagctgtt
    12721 ttcactaaat ttagcttcgc agattggttc taatacttgt tttatacatt gttgtataag
    12781 cctgtcccac atacaaggaa tacctagagg tctggtttta ccatttggtt ttggtatttc
    12841 ttttcgcctc actggcttag gtcgataccc atgtggactg cctgcaacaa tgtatcttac
    12901 ttttttgaca actgtttctg ctggcaattt gccaatatct ttaattattg taccgtctgt
    12961 tcctgctgtt ttactgcctg catttgcttt gatatttcga tatgccagta atatattttc
    13021 tctcgatagg ataatatcca taagatgagt gaaaatatct ccattcttac ttttggcata
    13081 taaatcatca aaggtgtttt gcatttcgta atattcagcg tgtcttaaat cttctacaca
    13141 caatgtttca tttttatttt taggcataag gcttcactcc tttacttgaa attgagtgag
    13201 cttttttatc ttactcgtaa tccttattga aacaacataa tacttttcta atatatacac
    13261 gacttgaggg cattcctcca ttctcattac aagaatttct taggttcgcc ctctgctttt
    13321 cagcattagt tcaactgctt attgttcttc gtcagtttat tctcttgatg agaacccaat
    13381 acctttcctc gttccgataa tcttatctat acatatatat ccttaggtca ctagctataa
    13441 gcctgctggc ttgataccgc ctgtaacgtt atatggcatt tcataaccta tattcttact
    13501 ttgccacacc agctacgatt tctcgtacct ttgcatttct acaaagttca aatttagacc
    13561 cgtacattcg ctgtttcgtc agttccttat agaacattct aaccatagat attttataga
    13621 cccccgacct gttggatacg ctacccacct ctggatagtt ttcgatagaa gatatatgtt
    13681 catcaactat tacggtatct ttcagccgtc tttaccgagc ttcaaacatt ctgagtttcc
    13741 tcatacaatg cttgtcggag gctcagggca ggcgtttcag agcgttactt catcattcca
    13801 cctgtcagat tatcagttct cctaataacc aaactttttc gttcttttat tagtgcctta
    13861 gcttttcact aaggaacgag tcgcacataa attttgtccg aaattcatct tgtcactttc
    13921 ctttcttttc cattgctcga tccgctgctg cacttgcatt catcaagcac atcacagtaa
    13981 caccaagcat actgccacca aataccaaaa aaatatcttt tacaattccc atgacgattc
    14041 ctcttttcat ataatcaaat tttcaattgc catactttgt tgctccaaaa tctttttatg
    14101 tcggtctgat aagcgtgcat tctgtaccat atcctggata taggttgtcc gattcaatcg
    14161 atccaactcc ttagccattt tccacgtagg ggcgacttgt cggcctagcc aattcaaggt
    14221 tcgttcaatg gtatacggtt ttggctcgga agttaattga atctctttcc gattccgtcc
    14281 aataaaacgc ccccattgtt cattcaaggg ccagttggtt cgccttttac cttctacttt
    14341 atccgcaaat cgcaagtaac gattgataat ggaaaacgtg gtgctctcaa tgctacgacc
    14401 ttttaacaaa tcttgaatcg catgaaaagc acggtcattt ttcagtcgaa tctcaaaacg
    14461 atttttcgtc tcagtttggt ctaatggaat ccctaacttg atatattgtt catagtcttt
    14521 ttcatacaaa cagaaataaa cctcactctt gagactgccg atatataagg tattgcccat
    14581 gccgtccttt tcatcagcct ttaaaagttc cccggaacga taacttttaa aggtacgaaa
    14641 caaggagata cattcttcct tctgacattt tttcgttagc tcaggtatat ccaatagccc
    14701 cactcgatca ttgattgcca agtccaagcg tttcatcacg ccaccggcct ttagacaatc
    14761 ctcgaaaaag tcgtaccagc tacgcttttg agcgagtaaa aaagtttcaa attgtcggca
    14821 acctcgcccc tttaattcta aaagcacacc tttatcttct tcatgagaca acatcaccac
    14881 aatatcaccc atgacatact gttcttgata ggagtaaaag gcataatctt catggagcat
    14941 atactcaaat ttcaaatgga gaatttcttg aataattttt cgtgcatccg ttgtgggaaa
    15001 gcgaatcctt acatagtcaa acagtaacgt caaaggcaaa tcgggattaa agctttccag
    15061 ttggtcaaaa attttcctca tggtttttat agatgcggtt acgccaccat tttctatctg
    15121 atttaagtac ggccgactaa gtccacaagc cgtagccaat ttattttgtg aaacgccgta
    15181 ttcgttgcgt cggtctttta atagccgata atctaaattc cgttgtgcca agttctcacc
    15241 tccaaattca aggtgttaac tttttcaaat gagttaacac ctatacaaat tacttactat
    15301 ctttgataca acaagcattc ttaatggttg cttacttatt ttttgtgttt ttgtaccccc
    15361 ctgttagata cgggggtgag acatcatggt cggctaacgc cgtccatgaa caggcacagc
    15421 accacggagg atttctgctt cgcgaatcct ccgcggtcag cgcctaacag tcagttgtgt
    15481 tggtttaggt tactcatctg taataccatt tacttccaac tctgctttca tttctaacaa
    15541 gtattgacga atatctggtt cttttgcttg gtccgcaatc cgctcaaatt ctgcaattac
    15601 ttgatttatt tcaattcgag catccgtctc ctcattcatt aaatatggat cgccagcgac
    15661 tttgacacca ttcttgcgaa tatcaaattt taaccgtcgc aattgttctt ctaattctgg
    15721 gtctgactga atctttccaa tcacccaata aatttctcca atcaactcat cataaaccat
    15781 gtacatccaa ctcttttaat cttctggcaa tatcaaaaat gaccggaact gttacagagt
    15841 ttccggcttg cttatacaac tgactatctg aattgacttg agaatctcga tcaaaagccc
    15901 aatcgggaaa gccctgaagt cgccaacact ctctaggtgt tagcttccga atttgatact
    15961 gatccgtgac gatcgcttgt tggtctcctg ttagtaaggt atgaacactc tgttttccca
    16021 gacgacctcg gcgacttgtg gaattaggaa aagccagatt cacactgtct tctggcttca
    16081 cctcttgata ttctgtttca ttttttcgaa tcatgatttt tgtaccacct tgtttcgttg
    16141 acaaggtggg ggcggttcca gtaacttcat aaactcga
//
LOCUS       DADVXE010000060        16087 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.061, whole genome shotgun sequence.
ACCESSION   DADVXE010000060 DADVXE010000000
VERSION     DADVXE010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.061"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..1180
                     /locus_tag="KB913_002146"
     CDS             <1..1180
                     /locus_tag="KB913_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6820484.1"
                     /translation="AQFIKGKLDDSPSYCEHCRSVRIIRNGSYTTRTQILKVKEKLTI
                     LELKRTRFLCHDCGRTFSAKTDLVDEHHQLTKELKQAILMELYENQSRKLIAKKYFVS
                     DGTVTRILREATKHYQSRMNFLPTVLCMDEFKSMKSVSGSMSFICVDGTTHQLFTILE
                     DRRLYKLTQYFLHFPRKARLKVKYLVMDMNASYCQLLKTVFPNAEIVTDRFHIVQHIN
                     RSFNQLRVQIMNRFRTSHSENQKKYRRLKRYWKLLLKDSTTWEPLKRHYHRLFKRPIS
                     QTEIVDELLSYNEELRTAYHFCQLLRYYFVKRGTEGFQETLKTISSTLPQSFKKKFTI
                     FHCYQSGISNAFKVSHSNGVTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN
                     "
     gene            complement(1563..2291)
                     /locus_tag="KB913_002147"
     CDS             complement(1563..2291)
                     /locus_tag="KB913_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HBB6820485.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(2269..3843)
                     /locus_tag="KB913_002148"
     CDS             complement(2269..3843)
                     /locus_tag="KB913_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6820486.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            4072..5010
                     /locus_tag="KB913_002149"
     CDS             4072..5010
                     /locus_tag="KB913_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6820487.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            5022..5933
                     /locus_tag="KB913_002150"
     CDS             5022..5933
                     /locus_tag="KB913_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6820488.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            5957..7429
                     /locus_tag="KB913_002151"
     CDS             5957..7429
                     /locus_tag="KB913_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6820489.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            7480..8091
                     /locus_tag="KB913_002152"
     CDS             7480..8091
                     /locus_tag="KB913_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6820490.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            8121..10034
                     /locus_tag="KB913_002153"
     CDS             8121..10034
                     /locus_tag="KB913_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HBB6820491.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            10162..13143
                     /locus_tag="KB913_002154"
     CDS             10162..13143
                     /locus_tag="KB913_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HBB6820492.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            13140..14801
                     /locus_tag="KB913_002155"
     CDS             13140..14801
                     /locus_tag="KB913_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HBB6820493.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            14841..15773
                     /locus_tag="KB913_002156"
     CDS             14841..15773
                     /locus_tag="KB913_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBB6820494.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         5212 a         2606 c         3222 g         5047 t
ORIGIN      
        1 agcgcagttt attaaaggaa aattggatga ctctccttcc tattgtgaac actgtcgatc
       61 ggttcgtatt atccgcaacg gttcctatac gacacgcact cagatattga aagtcaaaga
      121 aaagttaact attttagaat taaaacgtac ccgttttctc tgccatgatt gtggaaggac
      181 cttttctgcg aaaacggact tagttgatga acatcatcaa ctaacaaagg aactgaagca
      241 ggcaattctc atggaactgt acgaaaatca atcacgtaaa ctaatcgcta agaagtactt
      301 cgtctcggat gggacggtga cacggatctt gcgtgaagca acgaagcatt accagtcacg
      361 tatgaacttc cttccgacgg tgttgtgtat ggatgagttc aaatcaatga agtctgtttc
      421 tggttccatg agttttattt gtgttgatgg gacaacccat cagctattta cgatccttga
      481 agatcgcaga ctttacaaac taactcaata cttcctgcac tttcctagaa aagcccgttt
      541 aaaggtcaag tacctagtga tggacatgaa tgccagctat tgtcagttgc ttaaaacagt
      601 ctttccaaat gcggagatcg taactgaccg ctttcatatt gtccaacaca tcaatcgcag
      661 cttcaatcaa ttacgtgtcc agatcatgaa tcgttttcga acctcacact ctgaaaatca
      721 gaagaagtac cgtcggctca agcgatattg gaaactctta ctcaaagatt ccacgacatg
      781 ggagccactc aaacggcatt atcatcgact gtttaaacga ccaattagtc aaacagaaat
      841 cgttgatgag ctgttaagct acaacgaaga attgcgaact gcgtatcatt tttgtcaatt
      901 attacgctat tatttcgtta aacgaggtac ggaaggcttt caagaaaccc ttaaaacaat
      961 ttcatctacg ttacctcagt cgtttaaaaa gaaattcacg atcttccatt gctaccaatc
     1021 gggtatttca aatgccttta aggtgtccca ctcaaacggc gtcactgagg ggctgaataa
     1081 caagatcaag ctgattaaac gaattgcgtt tggttatcgc aacttttata actttcgggc
     1141 acggatctat ttacaacaag gtctgatctt tgaaaactaa aaaaatatgc ggcgcacaga
     1201 acgcgccgca tatcggacta agttttattc aaatttgtct tcaccaacac gatttgacga
     1261 agagcctatt taaataacta catccattta ttctatcttc taaaatagcc tttttcattt
     1321 cagttaaata gttcagcgcc atttttgcac tcgacttgca tagtagtttt ttccatattc
     1381 ctcaacctca gcgggggttg aagacataag gaaaatccta tgcgttatgc tcaactggat
     1441 ctgattaaat attctaatgt atttttctct accatcatta aatggttaat agccaaaaat
     1501 caccactttt caatggctcc ttgttgtata agtataacta gaagatgaac acgtctgaga
     1561 aattatagaa gctttttacg gtaattactg gggctgtgtc cagtagtttt tttgaagaga
     1621 acagaaaaat agctcacgtg atctattcct actttttgac taatttcatc aatagataag
     1681 aatgtgtctt tcagtagagc acttgctctt ttgattcgaa agtctagcaa gtaatcatga
     1741 aaggaataac ctgtttcttt tttgaaggcc cgtcctaaat aagcgggatg gtaatggaat
     1801 tgtgtagcta catctttgag cgtaagcttt tcactataat tgttttgaac gtaatcaatc
     1861 acttgttgaa ttgactcatt aaaagaatca tcagttagag agttttgatt agctgctgat
     1921 ttacgcattt tttcttcttg tactaactta actaaataag gaaaatcaat gggtttcgtt
     1981 atgtaacttt taatagataa atcaatcccc ttttttgcat actgaaaatt ttggtgggca
     2041 ctaatgacaa tactagtaaa gtagcgattg gatgtttgtt gcaaagattc gattaattcg
     2101 agtccagaaa ttttccccat cgtaatatct gtgataagta aatcaaagcg ctggttttgc
     2161 aggtttttaa atgcttcgtc tccgtctgtg tagcagtgat cgataatgat gtcggggact
     2221 ttcttcaaaa gataatgcct tatgccttct acaattgtac aatcatcgtc aacaattgca
     2281 attctcaaca tgcatattcc cccctttttg tattttgata gtaatcgttg ttccgacgtg
     2341 tagttggctt tctataacaa aacgtgtatc tccaggatag agatgcttta tacgtcgaaa
     2401 agaatttgag atgccgatat tctcactata aggaatatca tcattaagtt tttgttgaat
     2461 atgctccagc ttgtcttggt ccattccttt cccattttca acgattttta acacataatg
     2521 gttggttgtt tcagttgcat agacagtcaa acgattttcc ttttttgatg aatcgaagcc
     2581 gtgtttaata taattttcaa caaatggctg taaagaaagt tttggtaaca ttaattgatc
     2641 aatatgatca atcagctgat agtcaaagtt atgtcgataa cgacgttgat gtagttgcaa
     2701 ggagaggtcg atattaatta attcctcttt caaatcaatt atgtcgggct gatatgtatt
     2761 attgcgatac aacttgctca ataaatatat actgtcgctg atttcttcgt catcattcaa
     2821 tatggcagtc attcgaataa attccaaatt attaaataga aaatgaggct cgatttgata
     2881 ttgaagtgct gcatactttg cttcttgctt caaccaatta ttttcataaa gtgttttttg
     2941 atatgtagca ttatctaaat aaaactgatt gatatgcata gcgatttctt tcaaatcacc
     3001 gactttgttt tcgatattga ttgacttgta gtctcctgta gatgaatgat ttaaggaagt
     3061 aatgatttcc tgatactgct ggatatagtt acgaaaactt ctatttaata attgatgaat
     3121 agcaagaata aacaaactca ttaataagaa aatcatgatt gccagaccta ataaggtttg
     3181 tgacgaataa tttggatttt catatacttg taatgtgtgg ttaccgatag ctatctgttg
     3241 cgtttttttc catttagaag gcgagatgtc ttcagataaa ttgacggaat caataccatt
     3301 agacaaagaa taattgtaat gtgttggaaa gagactcttt tttagcgcgt tgatcgaaac
     3361 gtctagaatc aatgtagcat cgggcatgtc ctcactaatg aaacttaatg aacgaataaa
     3421 agaaattttt tcgttttttg taggtgcgta ggcacttaag tatttttcgt aatctaatga
     3481 gatagatata tttttaactt catcatcttg cacaagtttt tttaagttat ctactaaata
     3541 ggtaggggag cgatcctttg acaaaatatc ttccatgtat tcagcaggtg atgagaggta
     3601 gtagtcatta aggttttctt ggaaatcata attttgatag atctctgtca cgataccgga
     3661 gagaatacga ttatatgttt ccatatagtg ggtgatttgc tgaatgtttt gcaggttttg
     3721 atttttttct ttttcaatca cattgatata ggaaaagaac aatgtgaaac aggcaagtaa
     3781 agtaataaaa aaaatcaata tgtatgtaaa acgcataata acttttgata aatcgttttt
     3841 cattcaaagt cctcattttg ataatctcta attttatgaa tcattatagc acatattaca
     3901 agtgatgtaa acgctttgca aacagggcta cttatgattg tgaatacagt ttccgtttaa
     3961 aaactattct attgtagagg tttaataaac taaaaataat gtataaaaaa ttaatgtaag
     4021 cgattaacca agtgggtata atcaaggaaa cgctgagaga ggagagacaa aatgaagcta
     4081 aagaaagggt tattaggaaa tctaaaaaaa aaccgagcat tgtttattat gcttttacca
     4141 ggtgcgttat ggttatttat attttgctat ataccaatgt ttggagttgt aatcgctttt
     4201 aaagatttca gaatttcatc aaggggattc tttacaagtt tgttcaacag tccttgggtt
     4261 ggctgggaaa atttcaaata tctctttgct tcgcaagatg cttggatcat tactcgcaat
     4321 acggttgttt ataacgttgt aggtattttg ctaagtactt tttgtacagt gtcattagca
     4381 atcattctga gccaaatggc gaacaaacgg ttattgaaaa agatgcagac atttatgatt
     4441 tttcctaatt ttttatcatg ggtagtcatc agttactttg tttacgcatt tttgagtacg
     4501 gataaaggat taattaatat tttactaagc aattttggtg tggaacccat aaattggtat
     4561 agtgaaccga agtactggcc ttttattatt gtttttacga gtttatggaa aggcgtaggc
     4621 tatggatcca tcatttatta cgcgtcaatt atggggatcg atactagtta ttatgaagct
     4681 gctttagttg atggtgccag taaatggcaa cagataagga atgtagtctt gccacattta
     4741 agatcgatta ttgtcattat gttgattttg tctgttggta gtatttttcg agctgatttt
     4801 ggattgtttt atcaattgcc aagaaattcg ggggctcttt atgatgtgac gaatgtatta
     4861 gatacttatg tctaccgtgg attaatgaat agcggagata tcggaatgtc tacggcagcg
     4921 ggattatatc agtcatcagt tggctttgtc ttgattttga ttactaataa gatagtcaac
     4981 aagttagatc ctagttcagc actattttag gaggaatcaa aatgatatca aaattaaaac
     5041 ggcagatgta cttttcgctg ccagtcgaac ggtttttcac aatattacta atcttattta
     5101 ctcttagctg tatttttccc tttattttcg taatcgtcat ttcattaaca gatgaaaaag
     5161 cattacaact caacggttac gaattattgc cggctcaatg gagcactgat gcatatcaat
     5221 acttaataca agatggcgga cagttacttc ggtcattagg cgttacaatt atgattacag
     5281 tgattggaac gttgattact gtttttatga cgggaaccta tgcttatgtt ttatcaagag
     5341 cctctttccc ttaccggaag ttctttactt tttatctttt ttttaccatg ttatttgcgg
     5401 gagggatggt tccttcttac ttagtgatga cgaagatgct tggcttaaaa aatacaattt
     5461 gggctttgat tctacctctt gcttttagcc catacaatgt cattatttta aggacattct
     5521 ttaagaagtc gattccagaa tcgattatcg aatccgctaa aatggatggc tgtagtgagt
     5581 ttcgagtttt tttccaaatc gttttgcctt tagcgatccc aggggttgca acaataggtt
     5641 tattttcaag cttaggttat tggaatgact ggttcaacgc attgctgtat attgacacca
     5701 acaaattgat tccattgcaa tatttgttaa tgaagattca aaattcaatg gaattcttag
     5761 caaataataa tgacattaca ttagcgcagc aacaagcaat tcaaaatagc cttcctcaag
     5821 aatcaacacg aatggcaatg gtcgtagtag ctactttacc gattgcaatt gtttatccgt
     5881 tcttccaaaa atactttgtt caaggattga cgatcggtgg agtgaaagaa taaaaaagaa
     5941 taggagatgt taaaagatga aaaagaacat gcagaaatat ttgattggtg gtgcttctgt
     6001 actaaccctt ggcctattag gtgcttgtgg tagcagtaat ggcgaagcaa ataatgaaac
     6061 aggaaccaca aaagttactt ggtatcaggt tggagaagaa cccaaagatt ttgatgaggt
     6121 catgacaaaa gtcaacgaaa aattaaagga agaaatcaat gtagagttgg atatgcggct
     6181 gattccggac ggggattatc agcaaaagct tggtgtgatg atcaattcag gagaagaata
     6241 tgatatttgt ttcgtcaatg gcacagatta tgtgaattat gggaacaaag gtgctttcat
     6301 tagtctcaac gatcatttgg ataaagagtt gaaagattat gcagctgaat tgaatgaagg
     6361 atttattgaa ggtggggcaa ttaatggcga aacttatgga ttgccagtca ataacgatat
     6421 tgccacaacg gaatattgga cctttaataa agatttggta gatcaatacc aattggatgt
     6481 agagaatgtt gaaggtgtag aaacattggc tccagtatta gaaaagtttg cagaaaaaaa
     6541 tactgatacg aatattacgc caatcggtat gacccgtacc agtgtctgta ttccttatga
     6601 caatattatc ggtggtggtg taccgctagc ggttgcattt gaaggcgata cacaaacagt
     6661 tgttaatact tatgagactc cagaaatgat gacttatttg aaggctatgc atgagtttta
     6721 taaaaaagga tatattttga aagatgcagc cactgttacg acagatccat ttcgaattga
     6781 tagtaaaaac tggtttttag gtcgtaactc aagtggttat caaccattag cacaaaaaaa
     6841 attagaagct ctagcgggac atggattaat tttaaaacca gctggaaaag cttttaaaac
     6901 gactggattt gcaagagtgg caatgcatgc ggtatctgct tcaagtaaac atccggaagc
     6961 agccttgaaa ttgttgaatt atgtgaatac caatcaagaa gtagcggatt taatggttta
     7021 tggaattgaa ggaaaacact atgatcgcaa tgaagatggt tcgattactt taacaaactc
     7081 tgatgattat tatcaaggcg cttgggcatt ggtaaatact tatctagttt caaaaacttc
     7141 accgattaca gaagaaagta aaaaactaga agaagaaagt aaaaagtttc aaaatgaagc
     7201 accgatgtct cctattttag gtttctcttt tgacgcttct gattttcgaa cagaaattgc
     7261 aagtgtacaa aatatcgtgt cacaatatga agtactttta agctcgggaa cagttgaccc
     7321 tgaacaatat gtaccagagt tgttagaaaa actagaaaaa gctggattgg ataaaattca
     7381 ggcatctgct caagaacaat acgatgaatg gcgaaaatct aacaaataat tttttactaa
     7441 atgaaaagaa tagactaagc agttagtggg gggattcaaa tgaacgaaaa caaatggacc
     7501 aaaggattta attgggtttt tcaattgttg ttactaaact ttacttattt tatactaatt
     7561 tgtttaggat ttggaatttt aggttttttc cctgctacga tagctttgat tgctggcgtt
     7621 gtgaatcgaa aaaaatatgg cttgcaagag tctgtgaagt tcatgagtaa aatctataag
     7681 aaaaattttg ttagatataa tctatattgc tggtcagcaa ctttgttgtt ggccggcaat
     7741 attactacga tctggctttg ttggcagcaa agcgcaccat tgttttattt attaagtaca
     7801 ttattatcgg taattacact gttcctagtc tttgcaatgt tgaattgggt cgtgatcaaa
     7861 agtcttgggt tgtggatgat gggagaccga ctgattgact atttgctttt cacagcaacg
     7921 atgttgccaa cggtagtcat gcaaggcttg gtgcttggaa tttatttccg aatattgatg
     7981 attttgcctg tgatttttct gtttggcgga acagctgtaa cggtaatatt gattagtaaa
     8041 ttaactgaaa gagcgttagc aaagttgcct tgtcagatac aatcgcacta attttttcac
     8101 aaaaaggagt atttctttct atgaagttaa ctgataaaca agtagctaat atagccttta
     8161 tccagcaact tgagattcca ttgacacaaa aagatgaaga acaaatagac ttgattttta
     8221 ctgacacaaa ggctaatgtg cgacaaatca agattactaa aaatgagcag caacgaattt
     8281 gcttgtctta ttcacatgaa gacttgctgt atcgaggatt gtttatctgc cttccacgtt
     8341 ttttagctca aggaggagag atgccataca ttgaagaaac ctcgatcatt gagaccagtt
     8401 attcattaga tgcttctcgt aatggcgtga tgaataaaga gactctaaaa aaattcattt
     8461 cttacttagc gttgatgggg tacaacacat tgtatattta cacagaagat acctatgaag
     8521 tagaagacct tccatatttt ggttaccttc gcggagcgta tacaaaagaa gaagtgaatg
     8581 aaattgttga atttgcttct ggttttggca tagaagtagt tccatcgatc cagacccttg
     8641 ctcacttgac ccaatttttg aagtggtatg ctcaacaaga actgatggat gatcaaaata
     8701 ctctactgat cggtgaagaa aaggtttatg cggcaatcga aaagatgatt attgcctgca
     8761 aagaaatgta tcagacagag cgtattcatt tgggaatgga tgaagcctat caagcaggtc
     8821 tgggacgata tttaagcctg tatgggtatt gtgatcggac aactttaatg attcaacata
     8881 tggaccgtgt gttatcaatt gttgataaat ataagatgaa accaatgatt tggagtgatt
     8941 tcatttataa gctattagat gaaaccggta aagataggta ttacaatcct gattttaaac
     9001 tcaaagcatt agcagctaaa ggattaccag caggattaac ctatgttcat tgggactatg
     9061 gttcagatga agtttcctcc tatgagaaag taattgataa ccatttgaaa ttttgtgaca
     9121 ttgatcatta cgttttagct agtggtgccc atatctgggg gagactagcc ccgaatcatg
     9181 ggaaaacaga agcaattgtt tctgcagctg taaaagcttc taaaaataaa ggtgtacgtt
     9241 ctgtgatgtt aactacttgg ggagatgaag ggcaggaaac agagcattgg cattccttaa
     9301 ttggggcatt aaaattagca gattatgtct attctgaaga agagtggaat gattttgagg
     9361 aaatctacga tcgtttatta ggaacaggta gttatcaatt aatgtccgaa ttacgatatt
     9421 tcgatgaagt ggataccatt acaaataaca acttacaaat ggcttccgtg agtaaactgc
     9481 tactttggca agatccgtta gttggtatat atgactttca tgtagccgct cataacaaaa
     9541 ttgccactag aacaattggt acttattatc atgagttagc tcagaaatta gatatgaata
     9601 aaaattggaa tccaaaacaa ccaattttaa caactattcg tcaacgatat atacttttag
     9661 ctgaaatttt agcacaaaag gcagaactag gcatctattt acaacactgc tgtctggtag
     9721 aagaccttgc aggattaatg gaattagcga atcggtgtga agcactagcc aatcgagtaa
     9781 atgaattggc atctattcat gaaataattt ggtatcaaac atacaaaacc tatggttggg
     9841 aagtattaga acaacgatat gctgcattag ctcatcgtct gaaaaccgtt gcgcgtcgta
     9901 ttaaaaatca tcttcagggg caagatgccc tagaggagct tttggaagaa cgattaccgt
     9961 tttgtcaata tcaagtgccg cttgaaattt ctggctttaa ttatcggcaa agctcggtgt
    10021 caggctacaa ttaacgaagg aatcttcccg ttgaacggac cacttgctca tctaatggga
    10081 aagtggttcg ttttctattc ataagtagct taccactaac tcttttatta agaagagaaa
    10141 aaaagtagga agtgagaaaa tatgttatcg gactattatc aaaatctgtc agttataagt
    10201 gtcaatacag aaccattacg taattattat attccttatg caagtaaaga agaagcaaaa
    10261 caagagttag aaagggaaaa aacgagccag tttatcgatc tcaatggtac atgggatttt
    10321 cagtattatc cttctgtcca acagttaccg gaaaattttt ttcaagaggc ctttactgaa
    10381 agctatgata gaatttctgt tcctggagtt tggcaaacag agggatttga cttacctcag
    10441 tatatcaatg tatcttatcc aattcctttt gatccgcctt atgtacctaa tgatacccct
    10501 tgtggtgtat atcggcgtca gtttcaaatt gagcaaacag atgcacgctt ttacttaaat
    10561 ctagaaggag cagatagtaa ttgttttgtt tggataaata gaaactttgt aggctatgac
    10621 caagtgagtc atagtacatc tgaatttgat gtgaccaagt atttacaggt tggggttaat
    10681 gaaattcaaa ttctagtgat gaagtggtgt gatggtacct actttgaaga tcaggataag
    10741 tggcgaatga gcggtctatt tcgtccagtg tatcttcttc aacgaccaac tatgcatctg
    10801 acaagttatc aactacggac gttgactgat cctaaaaaag gaagcggaac attaatggtt
    10861 tcttttcaac gatttactcc tattgaagta tcgttaccta tttcttacga attattccat
    10921 cctgatggac gtctcatagc gaaaggggag tgttactcgg aacaacaaat aaatttggat
    10981 gttgaagatt gccttttttg gacagcagaa acgcctaaat tatatacatt acttttaaca
    11041 tgtaatggtg aatattttaa agaaaaagtt ggctttcgag cactgacgat caagaatcgt
    11101 aagttattgc tgaacggaac acctattaaa ttatatggag tcaactatca tgacgtgaat
    11161 cagcaaggca cgccagtgat gacccgagag cagttacgtg cagatttgtt attaatgaaa
    11221 aaattaaatg tgaatactgt acgaacggca cattacccta aatcaccaga tttttatgaa
    11281 ttggcggatg agattggtct gtatgtaatc aatgaagcag atttggagtg tcatggtgtg
    11341 gttaatctat atgatactga agcgaattat caactaattg ctaatgatcc gacattcgaa
    11401 aagccgatta tggaccgagt gatccgttct attcttcctt atcaaaatcg aagctctatc
    11461 attatgtggt ctatggggaa tgaatctggt tatggagtaa attttgaaaa agctcaagct
    11521 ttagcacgga aattggatga ttcacggttg attcataatg aacgctcgat tgaaccagtt
    11581 attgaccaag tgaatgattt tagtaacttg gatgttatta gtcaaatgta tcccccactg
    11641 gaagatgttc atcgtcattg tcaaagaagt gatactgaaa aacctttttt tatgtgtgaa
    11701 tatagccacg ctatgggcaa cggtcctgga gatcttaaaa cgtacttcga tttgattcaa
    11761 cagtatgatt cctttcttgg cggttgtgtc tgggagtgga ctgatcatgc aatcaataga
    11821 ggaactttag aaacgccatc ttatttatac ggtggtgatt ttggtgaaaa atatcacgac
    11881 ggcaattttt gcgtagatgg tttattgacc ccagatcggc aattaacagt aggtgcattg
    11941 gagtaccgta atattcattc gcctattcaa ctgattgctg tagatgagga gctgcaagaa
    12001 gtaaccttga gcaatataac tgcttttaca gccggttcag catttaacct ttctcttgaa
    12061 tggtatatag atggaaaaaa aacagtttat gaagtaatga atcctttcat acttgagcct
    12121 ggcaaaagtt gttcattgcc catcacagta cctacaacga ttcatggtgc tcatacggtt
    12181 gctgtttcgc tatctgttta taaaaatgat gagctttatg gacagcaaca gctctttctt
    12241 aaaaaagaaa aaatgagatt gccaagaact gctcatcata atgatgcacc acaaatttca
    12301 gtaaaaggca cagagctgat aatcaaagga gaatccttta tttatatata tcaattagca
    12361 aaagctgcgt tcacttctgt aaagatcaat caaaaggaac ttttggaacg tcctactcaa
    12421 ttttcaattt ggcgtgcacc aacggataat gatcgtaact tagtaaacaa atggaaagca
    12481 gctggatatg ctgaaatgtc tttagaaatc agaaaaaaag actggaaatt cgtagatgat
    12541 catctcctga tcgaaacgtc ttatcgagga gttattccag gattacagcc aatttttaca
    12601 atgcacatac agttgaaaat aaatggtgca ggcgtaatca accaaaaagt atcagtggag
    12661 aaaaatccga tttttccaga tttccctcgc tttgggatgg actggccgtt gaatgatact
    12721 ttttcgaagg tttcttattg tggctatggg ccgtatgaaa gttatcctga taagcactat
    12781 gctgcgatgt ttggtattta tgagatggag attgaggaat ttgatcagcc atatatcaaa
    12841 ccacaagaat atggtaaccg ctggcaatgt gattgggtat caatcaaaaa tcatcaagga
    12901 tctaccatga cggtttatgg aaactctaat ttttctgctc tgccttatag tcaagctcaa
    12961 ttaaccgaaa agtcacacca ttatgaatta ataaaagaaa atagaacttg gttcaattta
    13021 agttataaac aaaatggtat cggctcacac agttgcggtc cttatttaga agatcgtttc
    13081 cgttttatgg aagatacttt tgactggaat atagtgatta ctttcaaagg agaaaataga
    13141 tgaaagaaac aaagatcaat caagtcaaaa aaaaattatc tcgttatcaa gaagttgttt
    13201 atcgaaacca ttgcttaaaa tggtcaaaaa ataagctgaa tgttcgtttt aatggattat
    13261 tttatcgttt cgaacagtta gaagaagtct ggaaaccggt aacgaatttc caatcatgtc
    13321 ctgtacagct cataaatgat ccaaaagaaa catacgattt atgtataaca cacctttata
    13381 accagcattt gaaaaatgac ggattttatt taaaggttac taatgacaat caacttacga
    13441 ttgaatcagc aaaccttcga gggtttcaat atgctatgga agccttatta gagagttttt
    13501 tttcggtagg agatcaatta ttattaccgg aattgattct gaaacatgaa ccatcagtga
    13561 aaattcgagg aatcattgaa gggttttatg gtatcccctg gacacatgaa atgcgcctct
    13621 ctcttttttc atatatgaaa gataaccaat tgaatacttt tatgtatgcc cctaaagatg
    13681 atgaattatt acgtaaaaaa tggcgtgaac tctacgatgc gcaagaatta gacaaattta
    13741 aggagctttt atctgctgct gaggctagca atatcgattt ttggtactta attagtcctg
    13801 gaaatgatat tgatattacg tgtgaagaag acattcaagt tcttctgaaa aagttagaac
    13861 aactgattga gcttggcgta tttcaatttg gtctattaat ggatgatatt gactatcaat
    13921 taaaaggtgc tgctaaacgc cgttttcgag agccagcatt cgctcatgcc tatttagtga
    13981 atcgagtaga ggaatatctt agcactcggt tgtccaatca tgaattagtc atttgtccta
    14041 cagaatatga taatcgtcat ggttctcgct atttagcaac gttaagtcaa gaaataccag
    14101 aacaattacc gttcttttgg actggcccaa gcacgttagc ggcgtcaatt tctacagaag
    14161 agctgcagga aatggcttct gtctatcaac ggccgatgct gatttgggat aatattccgg
    14221 taaatgatta tttagaggat aaagaactat tgttcatgag tccatatgag aatcgaacac
    14281 cgaatctttc taaggagaga taccaggtta caggagtagt ttcgaatcca atggctcaat
    14341 tagaagcttc aaagtttacg atcaatagta tggctaatta cttatggaac tgtgagcgtt
    14401 ttgatccttt ggaaacttgg acgtcagtcg ttgaaaaagt agttggaagt aaactacaac
    14461 cagcttatct taccttaacc aatgcttttc caaatcatta cacaagcagt ctgctttcag
    14521 atgaagaatt actgctagcc aaagacccag aatgggtcac aaaagaaatg gctgctttag
    14581 tccaagcagt aaaatggatc cagcaagaac aacatacatc tagattgaga acagaattgg
    14641 agccttggtt acaagcaatc acagaaagtt ggactttctg gcaagaatgg caattaaaaa
    14701 aagatccaaa agaagcagaa gaatggttgg ctaagaaaaa aacacaccgc ataggacgtg
    14761 atttagtaac tgcccattta gagcaaatta tcaaaagtta gatatcttaa aaaataaaaa
    14821 gcaagaaaaa ggagaacaaa atggtcaaga gattaattag tgcaaactac agtgatgtca
    14881 agaaaatgac gtcaaaagag ttgaagcaat ccatcaaagc gagtgaagga cgggtgattg
    14941 tttgtgaaac ggttgctaat actcttccac aatctggaga aattacgaat gcagaagttg
    15001 cgtcagcatt tggtgcagat ttgattcttt taaatggttt cgattgttat cgtcctgcag
    15061 tttttggact accaaatgtg acgattgaga aggtttttga tctacagcaa acgattgaaa
    15121 acccgattcc taaattaaaa gaactagtcg gtcgtcctgt gggaattaat ttagaaccca
    15181 ttgcccctaa aacaaatatg atgagtgaga aagtagaaat cagccaagga agagcaagct
    15241 ctgttgaaac gatacaaaaa gcagaagaac taggagtcga ttttatttgc tttaccggta
    15301 atccaggcac tggagtaacc aatttagaaa ttactaaatc cgtaaaaatg gcaaaaaagt
    15361 atttttcggg attgattatt gctgggaaaa tgcatagcgc cggctcagaa gagccagttg
    15421 tgaataaaga ggcgattatt tcttatgcgg aagcaggcgc agatatttta ctagttcctt
    15481 cagtagggtc tatcccaggc tttttagagc aagacctaat tgaagcggtt cggttggcaa
    15541 aaaaatatga tttgttaacg atgtctgcaa tcggtactag tcaggaaagt gcccgaccag
    15601 aaacattgcg gcaattagcc attatgaata aaagttgtgg tgttgattta caacatattg
    15661 gagatgctgg atacggggga ttggcaccag cagaaaatat tttcgaaacc tcggttgcaa
    15721 ttagaggaat gcgacatacc atcaactgcg ttagccgctc gatcaatcgc taacaaaatt
    15781 aaataaaaaa tggttaaatt gattatttaa gtgggaacat acttgagata tcagctaact
    15841 tctgtcactt taaaaaaggg actgtgacag aagtgaaaat agacaaaaaa tatccgaaca
    15901 agagactagg atagcagaaa aactatcgtt ttgcaacgag gaccaactgg accgtaggag
    15961 caattctctt attgttcgga tatttcgctt gttcaaggac ttatgtctgt agtgcccttt
    16021 tttggtagga aaaatggtag ggaaccatat catttttaat gaaaatcaag catttcaaaa
    16081 gttgaaa
//
LOCUS       DADVXE010000061        15721 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.062, whole genome shotgun sequence.
ACCESSION   DADVXE010000061 DADVXE010000000
VERSION     DADVXE010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.062"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..295
                     /locus_tag="KB913_002157"
     CDS             <1..295
                     /locus_tag="KB913_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820495.1"
                     /translation="RRTAVSRAYYSAFKKSDEYLKENYDIIYNGSSGKGSHQTVWNLF
                     STVKELNTLGIHNSGYRMLEKRKCADYIPNETITKTDMALMNREAEKIINKLT"
     gene            complement(331..630)
                     /locus_tag="KB913_002158"
     CDS             complement(331..630)
                     /locus_tag="KB913_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820496.1"
                     /translation="MLFNETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(636..866)
                     /locus_tag="KB913_002159"
     CDS             complement(636..866)
                     /locus_tag="KB913_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820497.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(1302..1868)
                     /locus_tag="KB913_002160"
     CDS             complement(1302..1868)
                     /locus_tag="KB913_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6820498.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1868..2824)
                     /locus_tag="KB913_002161"
     CDS             complement(1868..2824)
                     /locus_tag="KB913_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBB6820499.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2824..3480)
                     /locus_tag="KB913_002162"
     CDS             complement(2824..3480)
                     /locus_tag="KB913_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBB6820500.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3850..5868
                     /locus_tag="KB913_002163"
     CDS             3850..5868
                     /locus_tag="KB913_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6820501.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5938..6144
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6295..8709
                     /locus_tag="KB913_002164"
     CDS             6295..8709
                     /locus_tag="KB913_002164"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBB6820502.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            9057..10610
                     /locus_tag="KB913_002165"
     CDS             9057..10610
                     /locus_tag="KB913_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBB6820503.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10991..12775)
                     /locus_tag="KB913_002166"
     CDS             complement(10991..12775)
                     /locus_tag="KB913_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820504.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12790..14511)
                     /locus_tag="KB913_002167"
     CDS             complement(12790..14511)
                     /locus_tag="KB913_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820505.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            14611..15372
                     /locus_tag="KB913_002168"
     CDS             14611..15372
                     /locus_tag="KB913_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6820506.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         5138 a         2858 c         3083 g         4642 t
ORIGIN      
        1 tagaagaact gctgtttcaa gagcatacta cagtgctttt aaaaaatctg atgagtattt
       61 gaaagaaaat tatgatatta tttataatgg aagtagcgga aaaggaagcc accaaaccgt
      121 ttggaatttg ttttcaacag ttaaggaatt gaatacctta ggaatacata atagtgggta
      181 tagaatgtta gagaaaagaa aatgtgctga ctatattcct aatgaaacca ttacgaaaac
      241 agatatggcg ctgatgaatc gagaagcaga aaaaataata aacaaactca cctaatgaat
      301 ttcaagcgag tttgtttgtt atttttttat ttaatctttg tatctttctg gatcaacgaa
      361 agtatacttt atatagtcat aacgccgatg atcgctacgt gcgtccggca cgtcagtcac
      421 gatatcaaac aaaaagtata cacccttctt cattctagtt ttcgcagcag gaattttgaa
      481 atagttctta ttagaatagt agagattgat taataagcta tcttcgattg ctaaaaagaa
      541 aacttctgaa ttccatactt tataaaaatc tttgataaat ctattcgaag ggtcaaattt
      601 aaaccataat tgtgtctcat taaaaagcat aaccattact ccgatctgtt tttaaaatta
      661 gtttctacct ctaatatata tcgagttttt attttgcctt cagagaatac tgtttctttt
      721 tttgcagtta caggttgttt attttcggaa aaagctaata tagctaagat tgaaacatcc
      781 atctggaatt tatctttttt actgctttga tcataaaagt ctgcatattc atcactgata
      841 ttttttctaa taaattcttc catcataaaa atcacctcaa aacgattata cgaacttacg
      901 ttcttgttgt aaagcgatat ttgaggggca aaaaaggggc ataatttgac tgatattaag
      961 ttagctattg atatatgaat gacatacaaa aatataaaat cttttaaaaa tgcttatata
     1021 tcaatgtttt tgccattctt ttatatatct gttatatgtc aaaaaaatgt gttcaatttc
     1081 aatttgtatt tgaataaaga ggttgtgaaa aagctgtcct gcatcaagta ataagaacag
     1141 ccaatcaaaa acagcttctc atgtttttga tttggttgga cttattaccg cagatataag
     1201 cttttgagca ccgtgaataa agaggttatg aaatcaacgc tctaacctga gtattagaga
     1261 aaaaaacgca aaacatatca tttatgtttt gcgtttttta tttatctttt tttctcaata
     1321 caatataaaa taggcggctg gttcttttgg ttgataaacc gataattcag cacattatat
     1381 gtttcctgtg gcagtttgga acaaaaagaa tcaaccatat ccagttcttt ttctccacct
     1441 tcatgaccat agtagacgac aaggatcaat cgtccgcgag gcacaagtcg tttcaatatt
     1501 tcttccatag ctgtgcgtgt agtctctggc atagtgatga ttgctttatc actttttggg
     1561 agatacccta gattgaaaat ccctgctttg agattttgtt gttcagctat cacttctcct
     1621 aacgtttcgt ggccttgtag aaacaatgag acacgttctt ctaactgacg ctgttctagc
     1681 ctttcacgag tagcatcgat tgcttgttgc tggatatcaa aactatagac atgaccagtt
     1741 tttccgatgt gttctgctag aaaaaccgta tcgtggccat tgcccatcgt tgcatctacg
     1801 acgtgatccc ctggttgcaa gatttcttgc agtaatgtat ggctgaaatg caaagcagtt
     1861 tgcaacatca gacgctcacc tttttccgta catcatattt tccttggaag ctatctctgc
     1921 gaagaagttc ttcatcaatt gcattcaaga cttcccattt tttcaagctc cacattggtc
     1981 caatcaagga atcccacggc gcatcccctg tcaaacgatg gatgatgatc tcttttggta
     2041 tcatttccag ctggtcgcaa atgacattga catagtcagg acggctcatt aattgaaggc
     2101 gaccttcatg atagtcccgc aacattctcg ttttgcgcat cagatgcatc aaatggagct
     2161 tgattccttg gatatctgaa tctaaaatgg tgcgtctgac attttctttc atcatttcta
     2221 aactttcgcc tggtaatccg ttgatcaaat gcgtacaaac acggatatta tgtttgcgta
     2281 atttagccac gccatctaaa taagtttgat aatcatgtgc tcggttgatc agttttgaag
     2341 tttcttcaaa agttgtttgc aatccaagtt ctacccataa atacatccgc tcgttcagtt
     2401 cagcaaggta atcaactact tcatctggca gacaatccgg tcgtgtaccg actgataatc
     2461 ctacgacacc tggtaaattg actacttgct caaatcgttc tttgattatt tcaactggcg
     2521 catgggtgtt tgtaaaattt tggaaataaa cgatgtattg ttggacatga ggccattttt
     2581 gatgcatcat gtcgatttct ttctggaatt ggattggaag agggtcttca ggtgcaacga
     2641 tcatgtctcc cgaaccagat acactgcaaa aagtacaacc gccatgggca acagtcccat
     2701 ctcgattcgg acagtcaaat cctccatcga tcggcacctt gaaaattttc ccgccaaact
     2761 catttcgtaa agcgtaattc caagaatgat atcttttatt tccttctgaa taaggaaaag
     2821 tcattaaaag tccttctttc tgtaagagtt atctatttgt tttctttttt ctctatacac
     2881 tggataagtc aggcacagcc aagaaagact gagtaagtaa ccgccgatga tatcagtagg
     2941 aaaatgaacg cccagataaa tgcggcttat cccgacactt actataataa acatcatcag
     3001 caattgaagc aatgtgcgta aggttctttt ttgaacaaaa gctggaagca gaaatagtaa
     3061 agaaccgtaa agaatcatac tgcctgctgc atgtccacta gggaaactgt aacttgtttc
     3121 aactactaag tgcgccaatg aaggacgctc tcgcatgaaa aatagtttga tcaccgggtt
     3181 gatgattcca gcaattacaa taaatccaga aacgaaccaa aatgtttctg cccttttttt
     3241 cttataccac atccataaag ccgcacaagc aaataaaatg atgacggtaa gaggattacc
     3301 gaatttagtc ataaagagtt ggtagctgtt cagatcagga taagaagctc tgacaatgcc
     3361 tgtaaaccac tgatcgaaac cagaaagcca cgacagatgg aactttacga tccagcccaa
     3421 aatgaaaaac aggacaagaa agaagctacc agccacctga aatgatgttt tatatttcat
     3481 acaattcctc ctttgaagca atgacttatt atagcatttt tggtccagcg aaaaaaacgg
     3541 taaagagata aaaccaatgt atgattcctc tttgaataac caatattctt ataaaaaaaa
     3601 taactgtaat cggaaagaca ttttttggta atgcaaatga aatgttaggg aaataaaatc
     3661 agtgtttttc gaaatccttt taaacaagaa cgtagacgta ggaagaactt gaaaatgaac
     3721 agaagttgtt cattacggta aattacaata tgattacaaa aaacaacaaa gctcttaaat
     3781 aacttttaat aaatattaag agaagttata attattaata atagataaat tgaagttgga
     3841 ggatagaaga tggaaaacat tgcaagaaaa gaacggagac gtttagaaca gaccaaacgt
     3901 tttcgaaaag caaaacgagg ggcagcaatc gtgggaactg cgatggtagg ctgttctgtc
     3961 gctgccccat tagtacagcc ggttcctgtt caagcggatg aaacacctgt tcagttcggc
     4021 gcaagaatca atacagcggc atttatcaca gaaattgcta cttatgctca accaatcgct
     4081 caagccaacg atctatatgc atcagtgatg atcgcacaag cagttgtaga aagcggttgg
     4141 ggcagtagtg cgttatctca agcaccttat tataatcttt ttgggataaa aggcagctat
     4201 caaggacaaa ccgtctacat ggatacgctt gaatttttaa ataatcaatg ggtaaataaa
     4261 aaggagcctt tccgacaata tccttctttt gctgaatctt tcaatgacaa tgcctatgta
     4321 cttagaaata cttcatttgg caacggttat tactatgccg gtacttggaa gagcaacacg
     4381 aaatcctata cagatgcgac agcttgtttg acagggcgtt atgcgactga tcctggttac
     4441 gcaggcaaat taaataatat catcgcaact tacggattga cccaatatga tacaccagct
     4501 agcggaaacg caggcggtgg agcgactaca ggtggcaata atactggaag tgcaggtagt
     4561 actggcggtt caagcaattc tggtaataca aactcaggtt cagcaacttc gaccacttat
     4621 actgtccaat ctggtgattc tgtttgggga atctcaaata aattcggtat cacaatggat
     4681 caattgatcc aatggaacaa catccaaaac aatttcattt atccaggaca aaaactgaca
     4741 atcaaaggta gccaggaaaa tggctcttcg acgaataatt ccggtaacaa taccaattct
     4801 tcaggaaatg ctggtacatc aaacggagga caaacaactg gtgcgaaata cactgttcaa
     4861 tctggtgatt ctgtttggaa gatctcaaat gatcacggaa ttacgatggc tcaattgatt
     4921 gaatggaaca atatcaagaa caatttcgtt tatccaggac aacagctaat cgtatcaaat
     4981 ggcggttctt ctaatgctgg agcaaatact ggctcaaata ctgggaatac aagtggctct
     5041 agttcgtcca gctcaagttc ttctaataca gcttcaggaa cgaaatatac agttaaagcc
     5101 ggagactctg tttggagcgt ctcaaataaa tacggaatta cgatggctca gctaatccaa
     5161 tggaacaata tccaaaataa ctttatctac ccaggacaac aactgactgt ttcaaacagt
     5221 ggatcaacaa acagcacgtc aggtaataca ggttcgtcaa ccaatacaaa taacagcagt
     5281 tcagttaata ctggcagcag ttcgtctcaa ggcacttata ccgtgaaagc aggtgaatct
     5341 gtttggagcg tggcaaataa aaacggcatc acgatggatc agttaatcga atggaataat
     5401 atcaaaaaca acttcattta tccaggacag caattgatcg ttaaaggtgg aacttcggca
     5461 aatacaaata caggttcaac tacttctgca gcgaaaccaa atacaccgaa tacgtctgct
     5521 acgacaagta catcatccac tggtaatacg atgtataccg tgaaagcggg cgagtcagtt
     5581 tggagcgtag cgaacaaaca tcatatcacg atggatcagt taatcgaatg gaataatatc
     5641 aaaaataatt tcatctatcc aggacagcaa gtgattgtga agaaaggttc atctcaatca
     5701 acaaaccaac aatcagttac tggttcgaaa acctatactg tgaaatctgg agaatctgtt
     5761 tggagtgttg ctgacagtca tggaattaca atggctcaac taatcgaatg gaacaatatt
     5821 aagaacaact ttatttatcc aggtcaaacg ttgattgtag ctaaataaaa tagctgttcg
     5881 aagaaataac gattgaattc cacaaaaata tttgttacta taaggctact taaatatgac
     5941 aacacttgaa aaggaagtag taaaaagact gaagtttcag agagcgcatg gctggtgaga
     6001 atgtgcacgg atgcttttga actcgccttt gagttgccct tgctgaatac ccgagtaagc
     6061 aagcggcggt gacggccgtt acaacgttcg aggccttttc actaaggtaa aattaggtgg
     6121 taccgcgtag attacgtcct ataaaaagag caatcttttt ataggatttt tttatttctt
     6181 ttgtgaagtt tgagaaaaca aagcaaaagg aaataaaaat aaacagattc tgccggtttt
     6241 ttcgttatat ttataataga aacaagtgtt ttcaatagaa caggaggaca gcaaatgagt
     6301 tacaatcata aagaaattga gaaaaaatgg caaaaatact gggcaaaaac gaatactttc
     6361 aacacccatg atgatcctga aaagccaaaa ttttacgcac tggatatgtt tccctatcca
     6421 tccggtcaag ggctacatgt agggcatcct gaaggttata cggcaacgga tatcctttca
     6481 cgtgtgaaaa gaagtcaagg atacaacgtg ctgcatccaa tggggtggga tgcattcggt
     6541 ctgcctgctg aacaatatgc gctagataca ggaaacgatc cagctgagtt tacccaaaaa
     6601 aatatcgaaa cattccgacg ccaaatcaat tctttaggat ttagttatga ctggaatcgc
     6661 gaagtgaata caactgatcc ggagtattat aaatggacac aatggatctt tacgaagctt
     6721 tatgaaaaag gtctagctta tgaagcagaa gtagcggtaa actgggtacc tgaattagga
     6781 acagttattt caaatgaaga agtgatcgat gggaaaagtg aacgtggtgg ctatgatgta
     6841 gtcagaaaac caatgcgcca atggatgctg aaaatcactg cttatgctga tcgcttattg
     6901 gatgatctag aattagttga ttggccagaa agcattaaag aaatgcaaag aaattggatc
     6961 ggtcgttcag taggagcaaa tattgaattt aaagtggctg gtacggataa atcctatacc
     7021 gtatttacga cacgaccaga tactctattc ggtgcaactt actcggttct tgcacctgaa
     7081 ctagatcttg ttagagaaat tacgacccct gaacaaaaag ctgctgtaga agcttatatc
     7141 gaagagacag ctaaaaaatc agatctaaag agaacggatc ttgcaaaaga aaaaacagga
     7201 gtatttactg gtgcttatgc aatcaatcca gttaatggca aggaaatccc aatctggatc
     7261 gccgattatg tattatcttc atacggcaca ggagccatca tggctgttcc agcacatgat
     7321 gaacgtgact ttgaattcgc tcaaactttc ggactagaaa ttcttccagt tatcgaaggt
     7381 ggagatgttg aaaaagctgc ttacacagaa gatggtacgc acatcaactc tgaatttcta
     7441 gacggcatga acaaacaaga agcaatcgat aaaatgaatg aatggctaga agaaaatggc
     7501 gtagggaaaa aagaagtcag ctatcgctta cgtgactggc tattctcccg tcaacgttac
     7561 tggggtgaac caatcccaat catccattgg gaggacggaa cagtcacagc tgtcccagaa
     7621 gaagagctac cattacggtt gcctaagaca aaaaacatca agccaagcgg tactggagaa
     7681 tctccattag caaatatcga ggagtgggtc aatgtcgttg atcctgtaac aggtaaaaaa
     7741 ggccgtcgcg aaacgaatac aatgccacaa tgggcaggaa gctcatggta ttacctgcgt
     7801 tatatcgacc ctcataacaa aaaagaacta gcagattatg aaaagttgaa gcgttggcta
     7861 ccagttgaca tctacattgg tggagcagaa catgcggtac ttcatttact atatgcacga
     7921 ttctggcata aattcttata cgatatcggt gttgttccta caaaagaacc attccaaaaa
     7981 ctatacaatc aaggaatgat cttaggcgaa aacaacgaaa aaatgtcaaa atctcgtggt
     8041 aatgtagtca atcctgatga tgtggtcgaa acttacggtg cagatacact gcgcatgtac
     8101 gaaatgttca tggggccatt agatgcttcg attgcttgga gcgaaaatgg cttagaagga
     8161 agccgtaaat tcttggatcg tgtatggcgt ttgatcgttg atgagaacaa taaaatgcgt
     8221 gaccgtatca ctacattgaa tgatggcaag cttgataaag tgtatcatca aacagtgaaa
     8281 aaagtgacag aagactatga aaatcttcat ttcaatacag caatctccca attgatggtc
     8341 tttatcaatg aagcctataa agtggacgct ctgccttatg aatatatcga aggatttgtt
     8401 caactactcg caccgattgc tcctcacatg ggtgaagaac tatgggcaat ccttggaaat
     8461 gatggtggta tttcttacgc accatggcca acatacgatg aagcagcact tgttgaagac
     8521 gaagtagaag ttgttttcca agtaaacggt aaagttcgtg cgaaaagcaa tgttccccga
     8581 gacttaggaa aagatgagct agaaaaagca gcattagcca atgaaatagt gcaagaatat
     8641 attgaaggca aaacagtcag aaaagttatt gcggtaccaa acaagttagt caatatcgtt
     8701 gctaattaat tggctctttg tcaataagga ctgatgagtt gtgcaaaatc aaatctgggc
     8761 cagaatgaac ttcattctgt ctcagatttt ttgttatttc aaattgatta attgattgat
     8821 caaaaaggtt ttgattttca tgttctcaaa cacgttcaat gtctttttct tctgaatggt
     8881 cttgtaagag atctctgtaa tcatcaaatt tttgtctatt aatcttagta ttttttgatg
     8941 tataaactac ctgaaattga gagtacatac caaattcata aattttttat tagtgggact
     9001 agtgattgta tggattttga cgcataatga atgaagtatg agaaaaggag agacaaatgg
     9061 atcaagaact atttattatc gaagtattat cagctaaaca aaaaattatc gagaaagcga
     9121 aaaaaagagc gaaaagaata atgttcaagc ttttaagctt agtatttttc tctggtttgc
     9181 tttttttcgg agctgtatcg ttcctatatc gccatatgag tgcagtagtc cgttcagctg
     9241 aagggatgca aaaattaaat aatttgtatc acttttcgtg gggagttggc ggaataacaa
     9301 ttgttgtgct tattgttttt cttctactta tttggctccg ttaccatcaa ttgtcgcgtc
     9361 atttcgatca atggcttagt caaagagcac aacagttttt acataataaa ccaacttctc
     9421 aagatgatga ctatctttat tttgagaaga cttcgacgag tcaagctttt cggatacaaa
     9481 aaagtgattg ccagttattg ctgagatcac ttgatgattt acctatctac ttaggcgaaa
     9541 gcaaatcaaa attcggaatg aacacattcc atattttttt actagaaaac gaacccagat
     9601 gggaaaaaag ccagtcttcg cctggtggat acctgacaac taagatgagt acattagtca
     9661 ctggtttttt cctcattctt ttagctggaa caatctatta tgggagatac actcagccaa
     9721 aaatgtcttc tcatataaat gctgcttctc acatgacaat gaactcaact aacgatacgc
     9781 atatacaaaa gacaaatgaa gggttgttag ctgatcctaa gcaaaaggta aatttgacaa
     9841 cacaaaagat aaatgatctc aaacttgata cagagacgca ctctctctat atgacaacag
     9901 atagtggtgc taattgggta tttgtgccga ttgattcgca atggttgcgt tttggcgaat
     9961 acaccctgac aacggggctg attcctgaag gttattggat ggacaacaca tatgatattt
    10021 ccgccgattt ctcatggttt atctattctt ctggggatga tgtacgtctg ctgacttcaa
    10081 gagataatgg taaaacatgg caaacgtcta ttatcaccca atcagttcag ccgatacgtt
    10141 atcgaaaagc ggtattttat ggcaacgatg gtctatttat ctgtacatca gccagtggga
    10201 tgtctgcaga aactttgtac atttacacta ctatggatgg cggaatcact tggataaaaa
    10261 gtggaagtac aatgatcaat cagccagtac aaaatgtcag cttcgttaca acttctttag
    10321 gttttgtttc gacacgtgaa agtttgtttt atacaaacaa cggaggacgc tcattcaaag
    10381 aatcagttct gtcgattccg gaaaactatc agacaggggg gatagatctt tttcaatcac
    10441 caaatgaagt tactcaaata agcgcgaata cgttagagac aaaattttat ttgttgaaaa
    10501 aaggaccaat cgatgcaggg aaaatgtttg cctgcctctt ccgttcaact gataacgggg
    10561 aaacatggca attcgttcag caactatcgc aagtagaaca aggagattaa agaagagaga
    10621 ttgtgagcct gacgttcagc accgagtcac aagaaacaaa ttcaaaaaac agcttctcat
    10681 atttgttgaa tagtgtaact cgtgattcgg agttgacaag agcaacaaga agcgattttg
    10741 aagtatagct tctcgtattt tacaagatcg tgtcttattg ccgataggtt gtctcttgaa
    10801 caccgtttat tcgtaaaaag ggattgtgac aagtcttttg tcactactta ccgaacgaaa
    10861 ctgaaggagc tatccaaaaa gtatcattag tattattctt tgtgtttcta gtggcaccac
    10921 tagtacattt aaaaaagcta tcgatcatgg actaatcata catgatcgat agctttttag
    10981 ataatgtttg ttacgctatc tgaaattgac tattataaag actggcataa agcgttggtg
    11041 attggagtag ttcagaatgt gttccttttt cgacgatatc gccattcttc attacaagga
    11101 tcatgtctgc attttcaatc gttgacaaac ggtgtgcaat cacaaaactt gtcctatctt
    11161 ttgtcacagc ttccattgct tgctgaatca atgcttctgt tcgtgtatct acgctagaag
    11221 ttgcttcatc taaaataacg acaggaggat tcgctagaat gactcgagca attgtcaata
    11281 attgttgctg tccttgagat aacgtgccgt tttcgctaga aatgatcgta tcatatccgt
    11341 ctggcagtgt tcgaataaag tgatcacatt gtgcgatttc agccgcttcg ataatttgtt
    11401 ctcttgtggc atccattttc ccgtaggcga tattatcagc taccgttcct tcaaacagcc
    11461 aggtattttg taaaaccatc ccaaaagaac gacgtagttc tccacgtgaa agcttggtaa
    11521 tatcaagacc gtcgaattcg atctttcctt tattcagttc ataaaaacgc atcagcagat
    11581 tgactaaagt cgtttttcct gcaccagttg gaccaacgat cgctaccgtt tgttttggct
    11641 ttactgaaaa atcgacttga ttcatcaata ttttatctga tgtgtaacca aactgtacat
    11701 ttttgaaagc tatttttcct ttcggttgtt ctaaaagtct tgcatctgga aggtctggaa
    11761 tttcatctgt ttcatctaat atctcaaata tcctatcgat tgctgccatt gcggattgga
    11821 tcgagttgat cacataagaa gcggtagaaa ttggttcaga aatctgattg atgtactgaa
    11881 gataagcttg taagaagccg atcgtcacac cacctgatag aacaagcata gcaccgaata
    11941 ccgcacttat gatgaaggcg agttgattaa tgaaacgaat ggccggatag atagcacagt
    12001 tcataaattg agcacgttta aaagcgttgt attgcttttt atttacttcg tgtatagcag
    12061 cttctgcatg agcttgctga ttgaatgttt tgaccactag attaccagct aagatttctt
    12121 ccattcgatt atttaaaaca cccagttcat actgattctg ttcagaaatc tgtttgtttt
    12181 tgttcgcaat cttagttgta acaattgaac tgccaacgat cagcaataag acgagcaaag
    12241 taagcttgct ttcgatataa aacagcatca gaccagcagc agctattgtt acgacagaag
    12301 taaaaaattg attgatacct gtcaataaca cttgagaaag ttgattgaga ccggtagttg
    12361 tccgactaat gatgtcacct acttgatgat tgtcaaaaaa cgacatcggt aatgttttga
    12421 atttttttgt gatttctttt cgcaccctca atgtgatctt ttcgcttaac gctgccattg
    12481 tccgttcctg aataaatgaa gtgatgctgc ttaagactga acagccgatc agcaataaga
    12541 cagggaacaa caatgcttgt ttgatatcac tgaaagaaag ctgtccaata cctgtttttc
    12601 ttatttctga taagagatca tcgatcccga ttcccatgat caagggcatg gctacgacta
    12661 ataggttccc gaataaactg catagaaaca atccgtaaaa atatttatgt tcaggtttga
    12721 tcattttcca aaaacgtatc aaagcacgcg tgttcaacgt ttttttcttt tccatcgtat
    12781 cccttctttc tatattcctt gtgattttgc aaactcctga taagtttggc aattagacag
    12841 tagttcttca tgagtacctt gtccaacgat ttttccttca tctaaaacaa tgatgttatc
    12901 tgcttgttgg attgtactga ggcgttgagc aacaatcacg agagttttct ccgacatgtg
    12961 tttatgaagg gctgctctta atgctgcatc tgttttatag tctaaagcgg agaaactatc
    13021 atcgaataca tagatctctg ctggtttgat caacgctcga gcaatacata tccgctgttt
    13081 ctggccccct gaataattag aaccgccttg agcaacaaag ctgtccaatc cgtcaggaag
    13141 ggtgtccact agttcttcta attgagcgat cttgatcgct ttagacaact cttctgttga
    13201 ggcatattca tttcccatct gcaagttgct taaaattgtc ccgctgaata agaaagcctt
    13261 ctgagggaca taactgatgt gggagcggat ctgttcttga gtcatttgag taagaggaat
    13321 accaccaagg gttacttttc ctatcgtagg gtcactaagt ctcaagagaa gtttcgccaa
    13381 actacttttt ccagatccgg tcccgccaac gatcgctgtt gtttttcctt taggtattgt
    13441 gaaatcaata tcttctagaa ctggatcaga gatttcagta tatttaaatg tgacatgttc
    13501 aaaagcagct gcatttgtct gatcaaaggt tggttcagct actgttttga tcgtctcttc
    13561 ctcaatttcg atctctgctt gcagtatttc ttctatccgt cgtaatgagg caaacgattt
    13621 agggataatg accaatacca tagctgcgat catcaagtaa gcaagtgtca gcatagagta
    13681 ttcgactaca gcagtcacga caccgatttg taatgctcct tctgctacaa gatttccgcc
    13741 aaaccacaaa atagaagcat aaacgattcc catgagcaaa aaagcaattg gagtgaccca
    13801 agcaaatatt cggttcactt tgatcatttg attagcatag tcagcaaagc tcttattcgt
    13861 tcgcttttct tcatatgatt gattatcaaa ggcacggatc atattaatcc cagtaaagaa
    13921 ttctctcaat gtgatggtga tccgatccat ttttggctgg atactcaaag ataaaggtgc
    13981 ccctcgtttc atcagtcgat aaacaatcca tacataaaaa acaacagaga tcaatgtaac
    14041 ccatgttagt aatagagaat aacgaaacat catgagaatg gtgaaaacgc aaataaccgg
    14101 tgctggtaag atcatttggc aaaataaaac aatcatttgc tggacattat cgacatcatt
    14161 cgtcattctt gtcaaaagag atccagaact aaaacgactg atatccttca ttgacagctg
    14221 ttggaattta cggaaatatt tctcccgcgt ttggaatcca aacctagcgg aagccaatgc
    14281 tgaaaagtaa ctagaggcaa ctgcagcgat tgttcctaga aacgctacaa gcagcatttc
    14341 aactccaatt ttttttataa ctgaggcttc gccacttgct atacctgtgt cgatcagctt
    14401 tgctactaat tttggtacac ctaatgtacc ggcgatttct aaacagatca tcacaaaggt
    14461 aaggagagcg agtcctttgt ttttctgtaa gaatgttttt aagatagaca tattattcct
    14521 ccttttttcc tgatactttt cgattctata ccttcaagta acttgaaggt caatagaaaa
    14581 aagaataaac tgaaaaagag gtgagaaaaa atgaaaaaaa tgtatacgat tggccaagta
    14641 tcggaactat ttgatttgcc aaaatcaacg atccgctatt gggatgaaca aggattaatc
    14701 cgttcaagta gacaagaaga gaatgattat cgattgtttg atatcgatga tatttttatg
    14761 ctttatgata tcgtttttta tagaaaatta gatataccga tcaaacagat gaagaattta
    14821 tatggaaaaa cattgacgga gttatatgag acacttgatg aaacagaaag aagaatccat
    14881 aaagaactgg tggtgatgaa acaaaaacaa aaagagataa gggagcaaaa aaaacagttg
    14941 aaattgatga tcgatacaaa cgaggaagaa tttcctgtag aagagatccc ttttgactgt
    15001 atgatctcaa cggagtttga agatattgtg gaaatcaaaa aatttctacc taactattca
    15061 agctttggga tgatgagtat gccagcttcc agttcacaga cgatgtatgg attttttatc
    15121 gaccctagtg aagtacattt atttactcaa gacgtgattt gggagaaaaa agatacggct
    15181 gtttatcgtc gattcttatt gaaatccgag atgaaccatg cggaacgtaa taatatttta
    15241 gaaatcagag aaagaatgta tgaaaaagga tggaaaacag gagaagtgat cggccagtat
    15301 ctattgacga atacggatga aaacaatatc agaactgaat attatcatgc atggatagaa
    15361 atgaaaaaat aggaaatatg tgtttaagat aactcgaaaa tgatggttgt tttagttata
    15421 aagaaaaatt ttctggttcg attacgggtt taatgtgggg gattattagt cgtggataga
    15481 tagaatttta gttttttaga ggaaatatgt ctttaaaaat ggaatggttg caattcttag
    15541 cgatatatac gatgtaattg tcctcttaaa aaagtatgga aaaataattg tattgggtgt
    15601 tatgtataat tcatggtgaa ctgagactaa tgagaagaaa aattcatatt gttatgagtg
    15661 agattgtatc agatgagaat gataaattaa ataggtgcat aaaagcatta cacttaaaat
    15721 a
//
LOCUS       DADVXE010000062        15642 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.063, whole genome shotgun sequence.
ACCESSION   DADVXE010000062 DADVXE010000000
VERSION     DADVXE010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.063"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(96..1139)
                     /locus_tag="KB913_002169"
     CDS             complement(96..1139)
                     /locus_tag="KB913_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBB6820507.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1516..2481)
                     /locus_tag="KB913_002170"
     CDS             complement(1516..2481)
                     /locus_tag="KB913_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBB6820508.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            2715..3560
                     /locus_tag="KB913_002171"
     CDS             2715..3560
                     /locus_tag="KB913_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6820509.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            3751..4938
                     /locus_tag="KB913_002172"
     CDS             3751..4938
                     /locus_tag="KB913_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBB6820510.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            4944..5300
                     /locus_tag="KB913_002173"
     CDS             4944..5300
                     /locus_tag="KB913_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBB6820511.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            5302..5640
                     /locus_tag="KB913_002174"
     CDS             5302..5640
                     /locus_tag="KB913_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBB6820512.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    5716..5972
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6035..7069
                     /locus_tag="KB913_002175"
     CDS             6035..7069
                     /locus_tag="KB913_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6820513.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            7062..7748
                     /locus_tag="KB913_002176"
     CDS             7062..7748
                     /locus_tag="KB913_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6820514.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            7772..8620
                     /locus_tag="KB913_002177"
     CDS             7772..8620
                     /locus_tag="KB913_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBB6820515.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            8817..9590
                     /gene="sufC"
                     /locus_tag="KB913_002178"
     CDS             8817..9590
                     /gene="sufC"
                     /locus_tag="KB913_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBB6820516.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            9603..10889
                     /gene="sufD"
                     /locus_tag="KB913_002179"
     CDS             9603..10889
                     /gene="sufD"
                     /locus_tag="KB913_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBB6820517.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            10886..12121
                     /locus_tag="KB913_002180"
     CDS             10886..12121
                     /locus_tag="KB913_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6820518.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            12108..12578
                     /locus_tag="KB913_002181"
     CDS             12108..12578
                     /locus_tag="KB913_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBB6820519.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            12583..13974
                     /gene="sufB"
                     /locus_tag="KB913_002182"
     CDS             12583..13974
                     /gene="sufB"
                     /locus_tag="KB913_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBB6820520.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(14072..15214)
                     /locus_tag="KB913_002183"
     CDS             complement(14072..15214)
                     /locus_tag="KB913_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6820521.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(15265..>15642)
                     /locus_tag="KB913_002184"
     CDS             complement(15265..>15642)
                     /locus_tag="KB913_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6820522.1"
                     /translation="NEILANNINPLIEEYANQRHSISKELFFKRANSKLQDKIRNGDF
                     KYGEKERMIDSLKQLLDEMDLAYKDISKYSSVEDFFYKITKNQFETEKFISDLSKKYN
                     FPYEKNSIIAKFLTDNHDKFKNN"
BASE COUNT         5101 a         2896 c         3311 g         4334 t
ORIGIN      
        1 attgttgttg ttagaaggat atctgcaaaa ttaaaaacag ttgtgattcg gacattgttc
       61 catgcgagaa tcacaactgt tttttcatgt tcattctaaa ctttgatcag ccaaataaat
      121 agtaaagcca tcactgtttg gagaagcccg acagctaatc cataagataa gaagcgtgta
      181 ccttctttca tgaattttgc aaagtctaaa cgcagaccaa ttgccgctaa agcagtgatc
      241 tcaaaccagc tgctgataaa atgtgccgat tggtcaataa ctacaggtaa agaaaacaag
      301 ctgttgacca aacaaaagat cacaaaccct aatacatacc aaggaagcgg taattttcgt
      361 tttttctgcg tatcagttgg cgtttcaaac agagctggtt gtttcttgtg catgaatttt
      421 tcaaacagat agacaacaac aacgagcatc ataatacgta gaatcttaaa tagcatggcg
      481 aattcgacaa cagaattgtc aagtaagctt gccccagcga ctacttgacc aacagattgg
      541 agtgtaccac ccaaaagtgc acttttttca atgagatttc caccaaacaa ctgtaatcca
      601 agaaaaggga gagtcaacat catcacagta cccagtagat tgactagtgt gatgatctgt
      661 cctttttctt cctctttcgc atggatggaa ggggcgattg aagcaatagc agaagaacca
      721 caaacagcgt ttcctccagc catcatcaaa gaagaagtat cgctgaattg cagtttttta
      781 ccaatcaagt aagcaccgat gatagtgact gacatttgca gtaacacaaa aacaattcct
      841 tttacaccaa tttgagcaat cgtttgagct gtgacagttg cacctagtaa aaaaacagag
      901 aattctaata gtttgctttc agcaaatttt gtgccgattg ctagaacagg ctgtttaaaa
      961 aaagtatttc ctaataaaat acccaataaa atagcaatag tcgctccacc taactgtggc
     1021 agataaatag caagaagcct gctgaaggca gcgatggcaa aagaaagcag taaaccgggt
     1081 aagatttcgc ggaccgctga atcctttaca gattttattg gatgtgacaa tgatttcatt
     1141 tgatcggttc ctttcgtcaa taaatactaa aagcatactc gaacatagta gcactaaacc
     1201 agtattttga caaaagaaca agaggtcgtg acaaaagtct tgtacgacct cttgtttcga
     1261 ataaacggtg ttccagaagt agcttctacg gaaataagcc gaaatttcac aaaaatttga
     1321 gaagcaattt tcgtaaattc cttcttattt cttgaagctg accacttctt ttacgacctc
     1381 ttggtaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaaccag tacaaaaaca
     1441 tgaacagctg tttttgtttg gccgttctta ttacttgatg cagaacagct ttttcacaac
     1501 ctattgaatc gattattaag cgattttttt agaaacaaat tttccatgtt tgctatgttc
     1561 tttaattaag aaacgtacgt aatgagcaag aacgtagaag acaactacac ttgcaaacag
     1621 acattccgca acttttaaga aatccaatac gctactatag atacctaaac tgttgaagta
     1681 atgaacagta gtaaatatag ctgttgcaga gataacaagc gggaatgtaa aggctgcata
     1741 gcttggataa aaacgaagct tgaacaaacg tggaagcata gacagcacaa cgaaatacaa
     1801 tacttgagat aaagcgaaca atgctacgac aagataaaaa ttaggttcag caaagttttt
     1861 aagataacct gttaggcaaa gagaaccagg tgctgcaacg atcgtaatca gcggacgtgt
     1921 cggatgagcc atatttctta cgaaaaagac acgtttgatg atgatcggca ataagaacgc
     1981 atagcagatc aatgaaatcc aaaagaaaat ttttccaata agtgggaaga agttcccggc
     2041 agttacagtg atgaccccaa atccaacgta aatgataaac cagcttggat aaattgcttc
     2101 aattgaaaga tcagctttga taacatggtg ataattgaaa taaaagacaa ggatcacttg
     2161 gaagataaca gcgcacagcc aaatgaattt gacaattggt gcaatacttt catatgaaac
     2221 aaaataagta caaataacca tgagtgacat cgtaaaagtt ggtgaaacgg aggcgatgat
     2281 tggatcatgc aacgtttgtt tcgtgtgttc gaataagata aacaatttaa caaaaatgaa
     2341 tatcataaga atcatagaga taccgccagt tagattgcct aaagcaacat ggtgatagtc
     2401 tttaaacaga tttccaaggg aagctaaccc aaggatcaac ccgcagatcg ggatcggaat
     2461 aattttcaaa aagttcttca tatataatat tctccttttt atttaataga ttttagtacc
     2521 aagatgaacg aatacattgt aaaatgaata ggaatgtatg attacgagca agcagacagc
     2581 tgattgtctt catctaagtt actagttgga tcagcaactg ttttgttgta catttctatt
     2641 atagatggtt ttttgtatat ttaaatcaaa tagtttttat agtaattatc ataaaaagtt
     2701 atggaagtgg tgccatgttt aagttattaa cgacttttcg agcagtatat gaaacaagaa
     2761 atttttccag agcagcagaa gtactgtttt tatctcaacc agcagtctcg aatcaaatca
     2821 aacagttgga gcgggaattg aatatcgatc tttttcaacg taacggaaga aaagagatgc
     2881 ttccaactaa gcaagccgac ttattatatg aacggacact ggttttgtta gaagaatggg
     2941 aagaaactca gcaaaaattg ctcaatgaac aaaatgaaga agaagtatgt cggatcgttg
     3001 cttcccacac ctttgctgtc tatcttttgc ctcagttgat gaaacatctg atcaaaaggt
     3061 ttcctaaagt gcattttgag atcgaaatca cgaattctca tgaatcatta gaacaagtag
     3121 cgaaacatga atccgatttt ggttttatcg aaaagccatt agagacttcc ggcgtacaaa
     3181 gatactcttt gatggaagac cagctagtca tcgctgggga cccaaaaagc aaattgtggc
     3241 ttgtaagaga agcaaactct ggtgtttttc attacacgca gcgttatttt gaagagatga
     3301 atatccaaga taagaagatg atcgtgaaaa gtaacgatgt aattgttgcg ttgctgaagg
     3361 aaggaatcgg tcgctcgatt ttgtctaagc gctctgttcc agaaaatgtg ccaatgactc
     3421 cgttgaattt ccatcgatat ttttatttca tccaacgaac caatctggtt tctgatcagc
     3481 tgctagagat tgccgaagag atccttcgat acaatgaaag cacagaaact tctcacagcg
     3541 aggagaatct cagctggtag ataattgcat gtatcaaaaa aagttctatg atacactaaa
     3601 gataagcagt aggcttttgt actgcatttg ctcaagcaac tgcacaaacg gaaagttaat
     3661 ttttcccaaa tgtctatgga aagactttcc attatctaac tggaccgcta taataatcag
     3721 cagtatggtt tttaagaaaa gggatgaaac atggaaaaaa aattaaaagc ttcgaacgat
     3781 aatcgtattg attatggcgt gattttacca gtctttctgt tatgtttgat tggtctgctc
     3841 tcattatatg tagcacttag ccatgatccg aacaatccag cagtcttgaa aggcgtaggg
     3901 atgcaagttg tctggtattt agttggagcg gcagcaatcg ttgtcatcat gcatttgaat
     3961 tccaaatgga tctggaaact gactccttac ctttatggtt tggggttagt ggtaatggga
     4021 ctcttgctca aattctatga tcagaattta gctgcttcaa cagggtctaa aaactggttt
     4081 cgattcggtg cgtttacttt ccagccagca gagttgatga agattgcgta catcttgatg
     4141 atggcactga tcgtaactaa acataatacg caagtaaaag aacggacgat gaaatcggac
     4201 ttttggctga ttgggaagct cttgatcgtg acaataccgg ttttagcatt gatcatggcc
     4261 caagatgact ttggaacgat gcttgtcttt cttgcgatct ttggcgggat tttcctgatg
     4321 tctggaatct cttggcgcat catcgcacct gtagtaatct tggcagtagt cgttggagca
     4381 ggaacgatct tcttggttac gactgaaggc ggaagagact tgctttataa agttggattc
     4441 aaatcttatc agtttgcacg tattgattca tggctggacc ctttccatga tacgtcagga
     4501 atgagttatc agccggccca aggacttttg gcaattggta ccggtggctt gtttggtaaa
     4561 ggattcaacg taagcaatat ctatgtgcct gttcgtgagt ccgatatgat ttttaccgtt
     4621 atcggtgaaa acttcggctt tatcggtggt gcattcgtca ttttcttgta ttttatttta
     4681 atctatcgta tgattcgggt gtgtttcgat acgaataatg aattttacgc ctatatcgca
     4741 agcggtttga tcatgatgct gctgttccat gtctttgaga atattggagc aaatatcgga
     4801 ttacttcctt taacagggat cccattgcct ttcattagtc agggaggatc ctcgatttta
     4861 gggaacatga tcggtatcgg gttgatatta tcgatgagat accaaaatga agcacctgca
     4921 agatcttcaa ggaggtaaga aaattgtaca ccttttactg gtacccgaaa tgttcaacat
     4981 gcaaaaaagc caaagcgtgg ttagaccagc atggcgttag ttatcaaacc gttgatatga
     5041 tcaaagaagt accgaaggcc tcaacgattg agacttggct agaaacgagt caagtaccaa
     5101 tccgtcgcct gttcaacaca agcgggatga aatatcggga acttggactg aaagatcaag
     5161 taggcgagtt tacggcttca aaagcgagcc aagtcttatc gacagatggt atgctgatca
     5221 agcgaccact gatcttacga gaggaccagc ttgttgcaat tggattcaat gaaaaaattt
     5281 atgaaggaga actgatataa aatggcaggc aagcatttga agaaaaagga caacctttgg
     5341 atcttattta atggaaaaga atactgtgtt ggtttgacaa atgaagcgca agaagaactt
     5401 ggagacatca cgtttgccaa tctgccaaaa gcaggacaat cgctaaaaaa agatgaacct
     5461 ctgatcgaag ttgaagcgga aaaagcggtc aatgaatttg ccagcccgct aacgggtaca
     5521 gtttcttctg ttaatgataa aatcggtgaa gatatcaata tcttgaatga ttcagatgaa
     5581 atgaatgcgt ggatcttaag tttcaaagat gttgatccaa aagaatttga cgaattataa
     5641 aatcagaaaa tcacttgaaa aaagttgaca ctgattcttc cagttgctat aatcataagc
     5701 aatcctatat gaaacgagaa agctttgaaa agaagagtac atgtcacgga cgtttgaaga
     5761 gagccctgtt tgctgaaaat gggtaacgaa aatgagatgg aagatggtct tagagcagag
     5821 taagcgagcg taagcaaact tactacggga gtgcccgtta cagcgcgaca gtatacggaa
     5881 agaagctaag tccaagtact ggaagaggct gttattgcga agtaacggta aatcaaggtg
     5941 gtaacacgga agttcaagct ttcgtccttt tgcttaaggc aagagggcga aggctttttt
     6001 gtttgaaaaa ttataagaga aagatgtgaa tggcatgtca ttaatccaac taacgaatgt
     6061 caaaaagaca ttcaatggga aaaacggaaa catccaagcc gtcaatgacg tttcactaaa
     6121 cgttgaaaaa ggggatattt atggaatcgt cggctattct ggcgcaggaa aaagtacatt
     6181 agtccgtctc ctgaatggac ttgagcttcc cacgagcggc gaagtgatcg taaacgatca
     6241 agatattaca aaattaaaaa acaaagaatt acgtacattc cgaaagaaaa tcggtatgat
     6301 cttccagcat ttcaacctgt tatggtcaag aactgtactt gaaaatatcc agctgccgct
     6361 ggaattagct ggcgtaccaa agagcaaacg taaagaacgg gcagaagaac tgttgcgttt
     6421 agtcgggtta gaaggacgcg gacaagcata tccttcacaa ctttccggcg gacagaaaca
     6481 acgcgtcggt atcgcacgag cattggcaaa tgatcctgag atcctgcttt gtgatgaggc
     6541 tactagcgca ttggacccgc aaacaacaga agaagtatta gacttattgt tagcgatcaa
     6601 taagaaattg aatttgacca tcgtcttgat cacacatgaa atgaatgtga tccgcaaaat
     6661 ctgcaacaaa gtcgctgtga tggagttggg gaaagtcgta gaagaaggag acgtattgac
     6721 tgtcttcaga caaccgaaaa aagaagtaac caaacgcttt gtacaacaag acatcgaacc
     6781 agaagctgat tcgacagaac tattagctga actcatcaaa gaaaatccaa gcggccgttt
     6841 ggcaactttg acctttagcg aaagaaatgc caacgagcca gtcatttccc aagcgattcg
     6901 acgctataac atcgatgtca acgttgtgta tggaaagatc aaacaagtga aagaaggttc
     6961 ctttggttca ttgactgtct tgatgactgg tgaaaccaaa gaattagatc aagcagaagt
     7021 gttcatcaaa gaacaaggag taggaattga ggtgatccat cgtggataaa agcttttcag
     7081 aaacatatct agattttaaa caaatcaacc cggaaacgat gaatcaggct atccttgata
     7141 cactatatat gacattaatc tcaatggtct tagtgacgat catcggatta gttttgggat
     7201 tgatccttta ctctattgga cgcaaaaaca aaccgtatgc tcgaatcatt tatggaatcg
     7261 tatcgatcat cagtaatatt ttccggtcaa cgccatttat gatcctgatg gttttgatca
     7321 ttccatttac taaagcaatc gtaggcacta tgctaggtgc gcaagcagcc attccagctc
     7381 ttgttttatc cgcagcacca ttttatgccc gtctagtaga gattgctttt cgtgaagtca
     7441 gccctggtgt actggaagca gcagatgcaa tgggagcaag ttactgggaa atcatctgga
     7501 aggtcttgat acctgaaagt attcccgcat tgatttctgg attaacagtt acaacgatct
     7561 cgatgatcgg atttactgcg atggccggcg cgatcggcgc aggtggactt ggaggtcttg
     7621 cttggcagga aggctaccag cgtggtaatc taacagtgac attcgttgcg actttaatta
     7681 ttttactaat cgtatttatc gttcaaggaa tcggtgattt cttaactaag aaaacagaca
     7741 aaagataata ggatataggg ggatgtagga tatgaaaaag aaaatttttg gatttgcagc
     7801 agcgcttttg ctgactgtag gattagcagc atgcggtaac aacagcgaca gcaaagattc
     7861 agcaaataaa gcagacgaca cgacattgaa agtcggcgct tcaccgacac cgcacgcaga
     7921 gattttggaa catgtgaaac cattattgaa agatgaagga atcgatcttg aaatcgtcaa
     7981 attcgatgac tatgtattac cgaaccaatc tttggaagaa ggcgacattg atgccaatta
     8041 cttccagcat attccttatt tgaacaaaga aatcaaagaa aaaggatatg actttgtcaa
     8101 tgccggtgct gtccacatcg aaccaatggg cttgtactct aaaaaagtca aagatgtttc
     8161 cgaattaaaa gatggtgcaa caatcattac ttcaaattct gaatcagact ggggacgcat
     8221 catcacaatt ctacaagatg ctggcttagt caaagtcaaa gatggagtag atctggaaac
     8281 agcaacattc gatgatattg aagaaaaccc taagaacttg aagttcaacc atacgatcga
     8341 cccatcactt ttagcttcta cgtaccaaaa tgatgaaggt gacctagttg caatcaacgc
     8401 aaacttcgct tacggcgcag ggttgaatcc attagaagat gccgtattgc ttgaaaagga
     8461 caactctcct tacgtgaata ttattgcgac tcgtaaaggt gatgaagaca gtgacaaaat
     8521 caaaaaactg attgaagtgc ttcaccgcaa agaagtccaa gaatggatca cagacaaatg
     8581 gggcggctct gttaaaccag taaaggctga tgcaaaataa ggtatggaac aaaaaagatg
     8641 agaaataagt ctgtaatggc ttatttctca tcttttttat acctattcta atttagaaat
     8701 caaaattgtt taataataaa taaaagatat ttgattttag taaggaaggt cattgcgctt
     8761 cattctcaat tagtctaaaa tgagtgagaa cgaaagagaa tttgggggta taatgcatgt
     8821 ctgtcttaga aataaaaaat ctacatgtgt cgatcgagga aaaagaaatc cttaaaggcg
     8881 taaacctaac aatgaaaacc ggagaaatcc atgccatcat gggacctaac ggcacaggaa
     8941 aatctacctt atctgccgct atcatgggca atccaaacta tgaagtaaca gaaggcgaaa
     9001 ttttgtttga cgggaaaaat gttttagact tggaagtaga tgaacgtgcg cgacttggct
     9061 tatttttagc tatgcaatat ccaagtgaga taccaggtat cacgaatgcg gaattcatgc
     9121 gtgcagcgat caatgcgaaa cgtgatgaaa acgacaaaat ttctgttatg gcatttttga
     9181 aaaagttaga tgaaaaaatg gctttactaa atatgccaga agaaatggct gaacgttatc
     9241 tgaacgaagg tttttctggc ggagaaaaga aacggaatga gatcctgcaa ttgttgatgt
     9301 tagaacctac atttgcaatt ttagacgaaa tcgattcagg tctggatatc gatgctttga
     9361 aagtcgttgc taaaggagta aatgaaatgc gcggagacaa tttcggtgca ttgatcatca
     9421 cccactatca acgattattg aactatatca cacctgatgt cgttcacatc atgatggaag
     9481 gccgagtagt catgacaggg aatgctgacc tagctaaacg tctggaagca gaaggctacg
     9541 ctggtatcag taaagaatta ggaatcgact ataaagaaga agaagcgtaa gggggagcaa
     9601 gaatgaaaga aaaaaactgg ctcgattatc ttgacgcggt aaatgatttt tctttaagta
     9661 aaggcgaacc tgattggatg agaaccttcc gtcaagacgc actagcgaaa gcagatgaac
     9721 tgccattgcc gcatatcgat cgggtgaaat tccatcgctg gtcgttattt gatgtgaaag
     9781 aaacacaaac catcagtgaa acaggcacga ttccggcatt tgatgcaatg aaagacaatc
     9841 ctgtgcttgt ccaacaaggt tcatggacga tttttgaaca actgcctgtg gaattagcag
     9901 aaaaaggagt catttttacc gacttgttca ctgcaatgat cgaatatcca gaactagtcc
     9961 aagaatatta tatgaaaaaa gcagtaaaca tgaacgaaga ccaattgact gcactccatg
    10021 tagcttttat gaacagcggt attttcctgt atgtgcctaa aaatgtcgtg atcgatgaac
    10081 cactcgagtc cttattcatt caagatggcg catccgatga gcacttcttc aagcatgtgt
    10141 tgatcgtggc agatgaacat agtgaatttt cttatctgga acgtttccag acaaccaaag
    10201 aacaagtagc aaaatcatca ggtaatatca tcgtggaagt catcgctaaa gctggttcaa
    10261 aaatcaaata ttcagccgta gatcaattag gagaaaatat tacttcttat atgaatcgcc
    10321 gtgggcacat tttacgagat gcttctgtcg actgggcaat tggtgtcatg aatgacggtc
    10381 atgtgatcgc tgactttgac tcagatttag caggagaagg tgcacacgca gaagtcaaaa
    10441 tcgtggcaat cagctcgggc agacaaatcc aaggaatcga tacacgagta accaataaag
    10501 cccctcatac gatcgggcat attttgcaac acggagtgat ccgagaaaaa ggaacattga
    10561 cctttaatgg tatcggccac atcttgaaag gggcaaaagg tgcagatgcc caacaagaaa
    10621 gtcgtgtctt gatgctttct gataaagcac gtggtgatgc gaatcctatt cttttgatcg
    10681 atgaaaacga agtaactgct ggacatgctg ccagtgtagg acgagttgat ccagaagaaa
    10741 tgtactatct gatgagtaga ggattgcata aagaagaagc agagcgctta gtgattcgag
    10801 gattcctcgg ttctgtctta acagcaatcc ctgtagaaca agttcggaaa gaattagtcg
    10861 aagtaatcga agggaagttg aatggatgat cgatgctaaa aagctacgca atgattttcc
    10921 tatcttattt caagacgtca atgatgaacc tttagtttat ctggataatg cagcgacgac
    10981 ccaaaagcca aaacaagtac tccaggcatt agcgtactat tacgaacacg ataacgccaa
    11041 tgttcatcgc ggtgtccata cgttagcaga acgcgcgacc catgattatg aacaagcaag
    11101 agaaaaagta cgggcgttca tccatgcaaa agaaacagca gaagtgctgt ttactcgtgg
    11161 tacgacgaca agcttgaatt gggtagccag aaccttcggc gaccgctata tcaaagcagg
    11221 agacgagata gtgctctctt acatggaaca tcattctaat gttatcccgt ggcagcagtt
    11281 ggcaaaacga acaggtgctg tcttgaaata tatcgaacta acagaagaag gcttcctgga
    11341 tatggaggat gcagcgaaaa agattacgga caaaaccaaa atcgtctcca ttgctcatgt
    11401 atccaatgtc ttaggtgtct tcaatcctgt tcaagaatta gctgaacttg tccatgaaaa
    11461 cggcggggtc atcgtagtag atggtgctca atctgccccg cacatggcca ttgatgtcca
    11521 agcactagac tgtgatttct ttgctttcag cggacacaaa atgtgcggac caacaggtat
    11581 tggtgtttta tatggtaaac gaaaatggtt agaagaaatg gaacctgttg aatttggtgg
    11641 cgaaatgatc gattttgtcg aattatacga cagtacatgg aaagaactac cttggaaatt
    11701 cgaagcaggg acaccaaata tcgccggcgc tatcgcatta ggccatgcaa tcgattattt
    11761 gcaaaaactc ggtatggaca atatccatcg atatgaagaa gaactagccg cttatgtgtt
    11821 gccaaaatta caagcaattg atggattgac tgtttatggt ccacaagacc cgaattttcg
    11881 gacaggagtc gttgcattca atttggatgg gttacatccc catgatgtcg cgacagcttt
    11941 agacatggaa ggggtagccg tcagagcagg tcatcattgt gcgcaaccgc tattgaagta
    12001 ccttgaagta tcagcgactg ctcgcgcgag cttttatttc tacaacacaa cgcaagacgc
    12061 cgaccgttta gttgaagcaa tcatggcaac aaaggagttt ttccaacatg ggactatcta
    12121 aattagacaa tttataccgt caagtgatct tggatcattc ttcccatccg catcatcgtg
    12181 gaagcttgac tgactcgaca agcaagatcg aattgaacaa ccccacatgt ggagatgtga
    12241 tcgaattgca agtcgatgta aaagacggaa tcatcaaaaa tatcgccttt gacggcagtg
    12301 gctgctccat cagtacggca agtgcctcga tgatgacaga cgccgtcatc ggaaaatcaa
    12361 tagaagaagc agaacattta actgtagact ttctacagct tgtccaagga aaagaagtca
    12421 aagatcccga ccaattaggc gatgctgcta tgcttggtgg tgtagctaaa tttcccgctc
    12481 ggatcaaatg tgcgacactt gcctggaaag cactaggaaa agcaatggaa aacgatggta
    12541 ccgcagcttt ccatcattac cacaaggaag aggagtgaga acatgggcgt accagaatta
    12601 gaagaatata aattcgggtt tcacgatgat gtcgaaccgg ttttcagtac aggagaaggc
    12661 ttgacagaag aagtgatccg tgagatgtca agaatcaaag gcgaaccaga atggatgctt
    12721 gaattccgtc tgaaatctct agaaacattt aacaaaatgc caatgcaaac atggggcccc
    12781 gacctttcag acatcgattt cgatgccatc aaatattacc aaaaaccaag tgacaaaccc
    12841 gctcgtgact gggaagacgt accagaaaaa atcaaagata catttgaaaa gattggtata
    12901 ccagaagctg aacgagctta tctagccggt gcttccgcac aatatgaatc agaagtcgtg
    12961 taccataata tgaaagatga attcgaaaag ttaggaatcg tctttactga cactgactct
    13021 gctttgaaag aataccctga attattcaaa gagtactttt caaaacttgt accgccaacc
    13081 gacaacaaat tagcagcgct gaattcagcc gtatggtcag gtgggacctt tatttacgtg
    13141 ccaaaaggcg tcaaagtcga tgttccatta caaacgtact tccggatcaa tgcggaaaac
    13201 acggggcaat tcgaacgtac gctgatcatt gttgacgaag gagcaagcat ccactatgtc
    13261 gaaggttgta cggcacctac ttattcaagt aacagcctgc atgccgccat cgtagaaatc
    13321 tttacaagaa aagatgcgta ttgccgttac acaacgatcc aaaactggtc agacaatgtg
    13381 tacaacttag taaccaaacg agcaaaagca tacgaaggcg caaccgttga atggatcgac
    13441 ggaaacctag gtgcaaaaac aacgatgaaa tacccaagtg tttacttaga tggaaaaggt
    13501 gcacgaggca ccatgctctc catcgccttt gcaggagcaa accaaatcca agatacgggt
    13561 gcaaaaatga tccacaatgc accaaataca tctagctcta tcgtctctaa atcaatttca
    13621 aaagacggcg gagaagtaaa ctatcgagga caagtaacct ttgccaaaaa cagtgcgggt
    13681 tcgatctctc atatcgaatg tgacacgatc atcatggacg aatggtcgaa atccgatacg
    13741 atcccattca atgagatcca caacagccaa gtctctttag aacacgaagc caaagtctca
    13801 aaaatctcag aagaacaact ctactatctg atgagccgag gcctgaccga atctgaagca
    13861 actgaaatga tcgtcatggg ctttgttgaa ccattcacca aagaacttcc aatggaatat
    13921 gcagtcgaac tcaatcgatt gatcagttat gagatggaag ggtctgtagg ttaataacta
    13981 tttcattgct cgaaacgttg atattaaagc gtttcgagcg tttttttatt tgtattttaa
    14041 tggttggcta cgtttttggc tacgtttgga attattcgcc cataaatttt gcaaatcggt
    14101 caccagtttt cttaacagat tgtggtgtga catgagcata gatattcatg gtagttttaa
    14161 tatctttatg acctaatcgt tcctgtactt cttttatcga cgcaccactt tcaaacaata
    14221 agctacagtg ggtatgccta aatccatgtg gagtaatttg aggctccatc ggtgtctttt
    14281 tgtaaatcca gtctaaccaa tcgtttacta cttgggggta gtacaacttg tttgtgtttg
    14341 tagtgaaaag aaactgtttt ggtgaattcg tgttatagcc atataagatc attattttca
    14401 tttgttcttg ttgccaaata cgcagttgtt taagtgtaaa atcatcaagc tgaatcgttc
    14461 ttgatgaatt tttagtttta ggtacttgta gaactacttg attaaactcg tcttgagcga
    14521 tagttttacc aattgttatt gttttattga aatagtctat atcttcccat tgaagcgcca
    14581 atgcttcgct tttacgcatt cctgtataag ctaataaacg gaaaaaagtg tacagtttaa
    14641 ctgaattatt ttctttagta ttctgtaaaa acagttgtaa ttgatctttc gtgtaaaact
    14701 tcaagggttg ttcttcttca atttttcttg gaagcaatgt tttagacata ggattatcct
    14761 tacagacttc cattgctact ccaaatttaa atatttgagc agttgttttt ctcaagaaac
    14821 catattgttt taatgttttg tgccattcat tcacctgttt ttggcaatag ctaacactta
    14881 ttttatccaa tcgtaattcc ccaaaagcag gtaatatatg gtttttgcaa aaacgttgag
    14941 caacggcaac agaagacggt tttactcttg ttctgtagtt atcaatccat aattcataca
    15001 actcttgaaa agttgtaaca ttgattttaa actcttgttt ttctttaaag tctacaagta
    15061 gtctattaag tgctgtttgc gcctcagctt ttgatttgaa tcttctacgc tttgtacgta
    15121 tatcttttcc agtcttggga tctttcccta aataagtttc aaatccccaa tatttttcgc
    15181 cattttgtaa tttataacta aaaaatgttg ccatttgatt ctctccttac ttcattattg
    15241 caggtagaga agttatttga agaatcaatt atttttaaat ttatcgtgat tatcagttaa
    15301 aaattttgcg attatactat ttttctcata tgggaaattg tattttttac taagatctga
    15361 aataaatttt tctgtttcaa attggttttt agtaatttta taaaagaaat cctcgacaga
    15421 tgaatacttt gaaatatctt tataggctaa gtccatttcg tctaatagct gttttaaaga
    15481 atcaatcatt ctttcttttt caccgtattt gaaatcacca tttcttatct tgtcttgaag
    15541 tttactgttg gctcttttga aaaatagctc tttagagata gagtgtcttt ggttagcgta
    15601 ctcttcaatc agaggattga tattattagc aagtatctca tt
//
LOCUS       DADVXE010000063        15604 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.064, whole genome shotgun sequence.
ACCESSION   DADVXE010000063 DADVXE010000000
VERSION     DADVXE010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.064"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..173)
                     /locus_tag="KB913_002185"
     CDS             complement(<1..173)
                     /locus_tag="KB913_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6820523.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="KB913_002186"
     CDS             complement(593..1714)
                     /locus_tag="KB913_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HBB6820524.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="KB913_002187"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="KB913_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBB6820525.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="KB913_002188"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="KB913_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBB6820526.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="KB913_002189"
     CDS             complement(4304..5215)
                     /locus_tag="KB913_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6820527.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="KB913_002190"
     CDS             complement(5232..6239)
                     /locus_tag="KB913_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBB6820528.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="KB913_002191"
     CDS             complement(6236..8365)
                     /locus_tag="KB913_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6820529.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8513)
                     /locus_tag="KB913_002192"
                     /pseudo
     CDS             complement(8370..8513)
                     /locus_tag="KB913_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(8666..9853)
                     /locus_tag="KB913_002193"
     CDS             complement(8666..9853)
                     /locus_tag="KB913_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBB6820530.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
     gene            complement(9946..12291)
                     /locus_tag="KB913_002194"
     CDS             complement(9946..12291)
                     /locus_tag="KB913_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6820531.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLENGITSI"
     gene            complement(12278..12667)
                     /locus_tag="KB913_002195"
     CDS             complement(12278..12667)
                     /locus_tag="KB913_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6820532.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            complement(12717..13613)
                     /locus_tag="KB913_002196"
     CDS             complement(12717..13613)
                     /locus_tag="KB913_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6820533.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            complement(13616..15463)
                     /locus_tag="KB913_002197"
     CDS             complement(13616..15463)
                     /locus_tag="KB913_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBB6820534.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
BASE COUNT         4705 a         3224 c         2583 g         5092 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg ttttcagtca agtccacaat cttgtgtaaa
     8521 agttcaacct catcaaaagc acaatgtttt gcgttgtgaa cctaactgcc atgcctttct
     8581 ttctgaggag agaggtcagg agcagtagcg cagcgactct tgatgtctct cctcagaaag
     8641 aagagactcg cacaggttca tggtgctaaa tgttattcga attaaattct aaatattttc
     8701 gtggagaagc cagccactca gtgtcttttt ccatcaaaag tgttccaatt atccgagtga
     8761 tggaattgat atttggaaaa atccgaatca ctcgttctct ccggcgaatc tcttcgttca
     8821 accgttccaa cacattggtt gtacgaatcc ttcggcggat attttcagga aaagacaaaa
     8881 tttgaatagc atcttcaaag ccgttttcta aaatgtcgca agcagcactt aattttgaat
     8941 cacaaccata tttttccaag aagtgctctt ttctttcacg tgtcaattca agttcagagg
     9001 ctttaaagat actcttcaac tcgtctttta catcagaaga aactttcttt ggcagcttat
     9061 caaaaatatt tctcaaaaag tgggcttggc atctttgcca gctcgcacct aaaaagttct
     9121 tgcgaacagc cttaactaac cctttgtgtg catcagaaat gaccagtttt acaccgaaca
     9181 aacctcgttg aacgaacgat tgaaaaacgg tatcccaatt atcttccgat tcgccgtctt
     9241 gaacatcaaa accaagaatc gtacgtcgtc catcagaatc aatgccgata ccaatatata
     9301 caccttttga gacaatacga tgattttccc ttactttcat atacagggca tcacacatga
     9361 aaaatggata ttccgagcct tctaggctcc ggtttctcca ctcaaaaaca aatggatcca
     9421 actgtttcat cagatttgaa acgaatgatt tagaaacagt cgcaccatcc gttagcagtt
     9481 caactgtttt agttactttg cgagtggaga caccagaaat gaccatttca atcatggcag
     9541 cgatcaaagc tttttcgctt cgctgatatc tttcaaagat agtaggacta aacttaccgt
     9601 ctctggttcg tggaacatga agttctaacg taccaattcg agttgtaaac gaacgatcgt
     9661 agtaaccatt tctttgtgat tgccgttctt ctgaacgttc ataggcattt gcctgaatat
     9721 attgatttcg ttgttcttcc atcagctgat taaacatgat agtcataagt gtttttgcgg
     9781 tatcattcgc accgctttcg tttataattg cttgaatttc ttcgctttca aaagtaaaat
     9841 gtacttgagt cattgatatc agtcctattc gagtatgttt tctgcaaaaa acattgtact
     9901 cctaactgag atcaatggct tttttgatgc ttcactttta cacaattata tggacgtaat
     9961 cccgttttcc aaatctcgca ggcgtttttg attgctttga tcctcctgat ccaaaccaaa
    10021 gaattccaag gttttcttga tttcatgaat atcggtactg cgaaaagcaa acttcaaccc
    10081 gatattattt tttaaacgtt catctaataa atcgtcgcta ttttgagtga cgaaatagac
    10141 cccagcattc atggcccgac cagcacgaac aagcttattc gataacgttt ttccttgagc
    10201 cacttgaaga aaactccaag cctcatccaa atcgacaatt ttgaagattt ctcggttact
    10261 atggataaag tccaaggcaa aagtggaaat gacgattagc atcgaaacac taagcaattc
    10321 catggtggta tattcttcaa aagtcgtttc tgcatccggt aaaaccaaat ccgccacttg
    10381 aatgatattt agctgtttat ctaaactaat cgattgggta atcgagccgt ctgagaaaag
    10441 caaatgagca aaatcataat cggtaaagga ctcgatatga tcggcgatat tttccgcgat
    10501 tggtgacccg tcttttcgca attcgttaat aacttgtaat aacccccgtt gatcactttg
    10561 agtcaccgtt cgaatggctt tacgtaacac aggaaacttc tccccgtctc gacttgaaat
    10621 tcctgttaaa aaagtcagaa tatcaattgc taaactttcc gagtctttct ttttcttcat
    10681 aatcacataa ggatcaagca gaccttgatt ttctgactta ctcgtcaagt tgaggatact
    10741 gatttcatcc gcaatttctg gcaaggtttc tttccaccct cctcgctccc cttttggatc
    10801 gacaatcaca gcttgaccac cgaacaaaac agcatagtag actaagagat tgttactaaa
    10861 ggatttacct ccaccaagag aacccaggaa agcggcggcc agcgcattgg ttactgaacc
    10921 cttgactcct tgtgaagcca atgccggttt caggtaaaca ttacgacctg tatccacatt
    10981 gtagccaaag taaatccctt ctaattctcc tagcatctga gtagccccaa aaccaagccc
    11041 cgccaaaaaa tcagacgtaa catactgaat atagtcgttc atatatcgtt tacttgaggg
    11101 taagaattct tcatgtagcc ccatcatatc gccaaagggc cggactagtt ttacattggt
    11161 atcatcataa aaatcgagca cttcatcaca gcgtcgcttt agttcatcca ctgattcggc
    11221 actcactcga accacataac tcagtttgta catagattct tttgactgat ccaaggtggt
    11281 ttccaattca tccacggaat ccaaagcatc taagacattg gaattcgttt cattgtcaga
    11341 ttggtaagca tgattgtcta aatctttcag ttcttttttc ttattacgaa cggtagctaa
    11401 agccttttta ttcgtcacaa tctctacatt catacttgtg tcgattggga atgtaaattg
    11461 ttgttgctgg taatagaaaa gttctgagga aggaaattcc atctccccca caattgtatt
    11521 aattgttaaa tacgctacgt acgactcatg attctcatgt tccatccgta agcaccttgg
    11581 tttttcttca attaaacaac gatttggacg taataagtca taacgtttca ccagtgtttc
    11641 tgattttagc tttttctttg gtagctgaaa ttcgtattct tcaaacggta tccctttttc
    11701 gccataaata tgttcaatca aatacgtcag gtcactcggt gtgactcgcc tgactttaaa
    11761 tcttcgagcc aatttgcttt ccattaattt ttcaagctta gaatagcagc gaatttcttc
    11821 attggataag gaaacaaaat cgcccatcaa atgatgattc actccataga caaattcttg
    11881 aagcccagaa aagaaagatt tcttgagact ctttagattg acttcttcat ctgtcgcaat
    11941 tagtttaaag ccaataaaaa agcgataatc aatctgacta tcgccaatca tggatactaa
    12001 tgcatctgtc tgtatatcaa ttcgttgttt cgctacttct ttgagtctac cggtaatttc
    12061 tttttttgat cgttcttgtg tggcgcgaat actactttct gtggcaattt gtaacgcatg
    12121 gatcttgcct tcacgatttt gcgcaattag ttggcgaaag ttatcatgca cttgaaattt
    12181 ctgttcgggt gacaaaaagg agtaattgta aggcactaat tcatagtagg caaaacactc
    12241 gccttcttgg ttaaagacga gattattttc aatatactta atcggataca tagttcacac
    12301 tccttacaag agtactgggt tcatcccatc gtttcttctg ttctttgact ttctttcctg
    12361 caaaagtcac cttaaatcgc aagtgatagc tgataaagga tcgtaaaaat cccagtggtt
    12421 tcttgccatc aaacgtcttt tgcgacataa accaagtgac agccaccggt atgcctaagt
    12481 attttaaaaa gacctcctct atcatagata gtggaggcac atgggcaaat acgatgacaa
    12541 acagtaaaga taaaacgaac caagccattt ggttaaaagt cacaggaaaa ggcaactgaa
    12601 aatcattgat tgcgtaaatg actttttcaa ctgcccagat actggtatag ctttttattt
    12661 ttttcatttt tcctcctaaa aagggcggac ataataatat gtctcaccct ctagtgttat
    12721 tctacaattt gtttaaaacc atagcgtttc gctctatttg taaaagcatc ctcgccacct
    12781 tccatcacag tacatattct tggcttgata ttgggttcat ctaccgaccc gcactgatca
    12841 gccgatattt cttttgaatc tcccatgcta atcaaccatt ctgaatcacc attaactggg
    12901 atatttgcat tatgagttac aattaaaatt tgtctgtttt ccttttttgt aatgatactt
    12961 cttacgatta agttattaat taattgacta tccaaatcat cttcaggctg atccaatatg
    13021 agtggtgaat ttccatacgc caaaatcata gaaagaattg cagatgtctt ttgaccagca
    13081 ctagcattcg ataaactaac tttttttcca tttagttcaa gtcggataac tactaaatca
    13141 tttggcttaa gggtttgtaa ttcaagaact tgtgcatcat tcaattttct tatagaattg
    13201 attaattttt tatctgaaaa aatactactt tccccactaa ctcttatatc aagtatgtca
    13261 ttatatatat cttgattagt aatggaattt tttgtcagct tatcaataag agatccaaac
    13321 tcactgtcaa aagtgtcctc cttattaata caagctctga gctctttaac ataattattg
    13381 aaatccctat ttggttgaat agtagcctct attcctgtaa tatcagaaaa aatttcgcgc
    13441 gaggaactac ttctctcaga atagagattt tgatatgatt tattcattct tgacattgct
    13501 gagtcaacct caacttggta atctttaagc tttatttctt gttgaataat ttcttccaat
    13561 cgctcttcag tttttgataa agattgatat aaagaatcaa ggttttgtaa catttttaat
    13621 tcatcttgag ataactcttc actaagtttt tgatacctct ttgatacctc tttgaaacct
    13681 cattatagtt aactttccaa tctgatttat tcagctctgc tctataacta tcaatttcat
    13741 ctgacatttc attaattatt gtttgaatct tagcccgatt ggtcactaaa ttcttaatca
    13801 attctccgcg gtgttcatca atttcgtctg taacttttat accattgcca aagtcaattt
    13861 tgtcaacact atcagttaga tttttgggaa tttccttaag tgcctccaca tcacgtttca
    13921 gttccctata aatatctgtc tcttttgaat actcatcata aacatcttta taactcttat
    13981 gagatagctt ttctacttgt ttttttaaat cttcaatttc aagctctacc ttcgccttat
    14041 cttgtatttc ttttttcaca gaaacaatat cccaatttaa ttttcttatt tcgtttacac
    14101 atgtttcaat ctcattttta tactctgaaa tcaaatcaga gttatatcca tctagtaatt
    14161 ctagtatact agtttgattt tttgaaattt cataaatttg tttttgagag tatatactca
    14221 ccttatcgga aatcattctc aaccgttctg tttctttttc aaccagacca ttctcttgtg
    14281 taaattcata aatagaatgt ctatcctgtg ttcttattat ttgatatttt gtccccttat
    14341 agaaaatatt cagtttcaca attgtatcct tcaaaaatat tccagagcca ttatgttcaa
    14401 tttgtgcaaa gttctgataa tcactttgta tttcagaaaa ttgatcaagt tctgcttcct
    14461 ttccaaggac atagaccaag aatcttgtaa tacaagattt gcctgttcct cttcctccaa
    14521 taattgaagt taaattatcg ctgaattcga ctacaacttc ttttgtgcta agagtggtcc
    14581 cagaaaagct taatttttcc aataaaactt cattttcatt aatggagaaa ttagaaaaat
    14641 cagaatgaac tcgagtttcg cctagcatta aagcatcgcg aagtgatccc aagtcaggtt
    14701 cgtccttcat ttttatatag gaatatcttg tgcctattcc ccaaagtcca tgttttgaat
    14761 ttcctttcga gtgtgggtta tcagaaaagc taagaaatgt catattattt ttttctgcct
    14821 caacaactga tttataccaa gattccaaag tatcttttcc aactctacca tcatatctgg
    14881 cattcacact atcatagata gtgtcacgct tagatgaggg aatcatttgt gagcgatttt
    14941 caaaaaattc tttttgaacc gtctgtactg catatatatt ttctgattca aatatctttc
    15001 ctagatttcc aaattttgct gaagaaattc cattaaactc atctatatgt gcaggaataa
    15061 cgagcaagcc ctcgtgctca gcaaaatcaa taacttctaa aactgatttc attgagcaag
    15121 ctgcagcgct ggcccaatcc tctcttttta tacccatctt ggttaagaaa tcagagatat
    15181 catttgtaca tgcactttta tcaaatagga ctagtaaatg agttccattt tctccacacg
    15241 ttaattccac tccaggaaaa aaatctaagc cattttcgat agccactttc ttatattcat
    15301 caatattttc ccctgtattg tgatcagtta atgcaacaca atcgagtcct ttgtttaaac
    15361 attcttctac ccattcctta gcagtaacct ttttatcctg aaagcactga ctcgcagttg
    15421 aatgaatatg aagatcacat ttgtaccact tattgccaac cattagtaac acccctatca
    15481 acaaatattt tctatttcag tatatcaaat agaaaagtaa aagtacgata gaaatttctg
    15541 gtcaattcta acaaatgatt tacattagtt caaaaacccc tcgactcgta accaaataat
    15601 tccc
//
LOCUS       DADVXE010000064        15399 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.065, whole genome shotgun sequence.
ACCESSION   DADVXE010000064 DADVXE010000000
VERSION     DADVXE010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.065"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            138..2198
                     /locus_tag="KB913_002198"
     CDS             138..2198
                     /locus_tag="KB913_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBB6820535.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2281..2850
                     /locus_tag="KB913_002199"
     CDS             2281..2850
                     /locus_tag="KB913_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6820536.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKSDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(3025..3831)
                     /locus_tag="KB913_002200"
     CDS             complement(3025..3831)
                     /locus_tag="KB913_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820537.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3969..5483
                     /locus_tag="KB913_002201"
     CDS             3969..5483
                     /locus_tag="KB913_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBB6820538.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5886..6869)
                     /locus_tag="KB913_002202"
     CDS             complement(5886..6869)
                     /locus_tag="KB913_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBB6820539.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6874..7521)
                     /locus_tag="KB913_002203"
     CDS             complement(6874..7521)
                     /locus_tag="KB913_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6820540.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7606..8238)
                     /locus_tag="KB913_002204"
     CDS             complement(7606..8238)
                     /locus_tag="KB913_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6820541.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8254..8805)
                     /gene="coaC"
                     /locus_tag="KB913_002205"
     CDS             complement(8254..8805)
                     /gene="coaC"
                     /locus_tag="KB913_002205"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBB6820542.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8802..9539)
                     /locus_tag="KB913_002206"
     CDS             complement(8802..9539)
                     /locus_tag="KB913_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBB6820543.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9536..10525)
                     /locus_tag="KB913_002207"
     CDS             complement(9536..10525)
                     /locus_tag="KB913_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBB6820544.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10783..11325
                     /locus_tag="KB913_002208"
     CDS             10783..11325
                     /locus_tag="KB913_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6820545.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11342..12427
                     /locus_tag="KB913_002209"
     CDS             11342..12427
                     /locus_tag="KB913_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820546.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12439..13245
                     /locus_tag="KB913_002210"
     CDS             12439..13245
                     /locus_tag="KB913_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6820547.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13246..14073
                     /locus_tag="KB913_002211"
     CDS             13246..14073
                     /locus_tag="KB913_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6820548.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14070..15143
                     /locus_tag="KB913_002212"
     CDS             14070..15143
                     /locus_tag="KB913_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6820549.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
BASE COUNT         4951 a         2781 c         3137 g         4530 t
ORIGIN      
        1 ttttcttgaa acaataaaaa atcaaaaaaa atactctcct aatagtccat cttcttttga
       61 ttttatttat ataatgaaat catcttatga aaattactac ttcatgttta gacaagagta
      121 gggaggacta agaataaatg tgttcaaaaa gacgttcaaa acaactaaat aaacacgctt
      181 gtcgtttaga taaggaacgg tcgtgttctg aaaaacacta cgttaagttt atgatgcgca
      241 cgatgctgat cagtttatct gtaggtgtct atatgcatgt acccgttcag gcaacgacac
      301 aaaccatcaa ggtcgtacgt acctctgttt ctgagaccac tgattcccct atcactatta
      361 ctcatacttt cactgatgca aatggaaaac agctacttcc tgcattgact tcctataata
      421 aagtcagtta tcctccaacg ataaaccact actggttaat tcctaacaaa acattatgga
      481 catcggaaac cggaagcagt gtgccgcttt ctatcttttc cgatatgact gatcctacaa
      541 aaggtgatca gttaaaacag atcactgata ttttgaatca tgctttgaca gatataaagg
      601 acggtggaag cgcacaagtt tcttatgtat atgaaaaaga ttattcacag tttgaaagaa
      661 agaaaatcga tgttctggca gggacaaaag tttcgatatc tgatctggta gaaaggctga
      721 agaacgcaga tggaacacaa ggagatatgt ccaaagtaat ttcaaacaat gggaatatcg
      781 tggatacgac taatacagga acatctacta tttccttgtc ctattttgat ccaattgctt
      841 taaaaacaat gactgcatct gctgtgatcc atgttcgtgc tgatcaaaca gctatcaaag
      901 gaaaagatct tcacttaaga acaggagaga gttacgcccc taaagatctt gttgaatatg
      961 taacaaaaag cgatggaact tcaggaaata aagaagaaat caaaatgaac gggacagtag
     1021 atactacaac tccgggagaa tatcccgttg tattaactta tatagactcg aaaacatcaa
     1081 atgtggcaga aacaacagct gtagtttatg tagaagcatc tgctgcttca tcgactgtca
     1141 tcactcattt tatagatagt caaacaaata aagaacttca agcagaaaca catatgagta
     1201 gtgtaaatcg tattcctgat ttgcgcctac ctgctgaatt ttctgatcga gtgccaaata
     1261 tagatttatc gacttatgaa caaaatggga aagtcacttc tatttctgat tggatgcaag
     1321 caaacggatt agacagaaaa agtcactggt cggagatcct tgaagtactt cactcagaac
     1381 tgatgaataa taggaagcaa tcaggagggg aaattacctt tacttatgtt tatataccag
     1441 acaatcgttc attagaaggt catgatctta ttgttcatcc aaacgaaaaa ataaacaaag
     1501 aagagttgat ccaatcagca acaaattcct taggtaaacc cgtaccgtta aaggatgtat
     1561 cggttacaat caatgaagta ccattggagg atggttattt gaccaaacaa acaggtgatt
     1621 ttacgattat gtatagttat catgacccgt attcactcca agaactccat gctcagtcac
     1681 tattacatgt tttaccatta aacaaacaga tagatcaaaa agaacaaaaa agacaagaag
     1741 aaagcttgtc agaaaaaaaa caacaaatgg ctcatgcagt ttctccaaca gggaaagtaa
     1801 aacaaacaag aagcctagag ttagcaagaa tatctagaaa aatctcagaa tctaataaaa
     1861 cgataaggca agaagctcat ttggccccac aagtttctgg attggaaaat gaaattttag
     1921 agcctaaaat aaaacaacaa tcagaaaaag aatttgttgc taaacagtcg gaagatcaga
     1981 aggaatcaga tgaccagaag gaaacgaaga aaaaacgctt gtcaactatt gattccaccg
     2041 atgagcatct gcagccgcaa gtaccacttc ctagtccggg aacacccgca cctggtggag
     2101 gtattccttc ttctgcttta ggagatttca tgcgaggtat ggcaggaaca tgggtatacg
     2161 ctaatcgaaa tgaatttgac gcagatgact ggttctgatt tatatctcta tctgttatag
     2221 tcaaataagt agctgagtca tatgttattt ggcataatgg agacgaggag ggatagaaaa
     2281 atgttagata aaacgttacc ttacgcagaa atctggatga caagaccact tcaacaaaat
     2341 gttccaatca cgcctttagc ggaaggtttt gaatttcgat tttatcaaaa agaagatgaa
     2401 tctgcttggg cggagattga gacttccgtt ggggaatttc aaacgacaga tgaagcactt
     2461 gagtattttc aacaaaactt tgctccttat cctgaagaac ttgaaagaag gatgtttttt
     2521 gtagagacaa aaaaaggaga aaaagtagca acctgtaccg cttggcgaaa aaaatcaaga
     2581 gagcaagtgt atccggtttt tcattggtta gcagtgaaat cagattacca aggaaaaggg
     2641 ctcgcaaaag cattgactgc cagagtcttg caagaatttc ctaccctcca tacggacgga
     2701 ccaatctatc ttcacacaca gacatggagc catcaggcga ttgctcttta taaaaaaatg
     2761 ggttttactt ttattgctga aaatctagac ggcacaccta atccagatta tgaaaaagtt
     2821 atgcaggttt taagtaaatt agataaataa cgaaatggtg aaataagtcc tcagtattgg
     2881 gataaaaaac gaaatagtca ttcctcatat cttacttttt tgagttaata ctatcggata
     2941 actaatggca tgccatacat tcaaaaaaga aggggcagtg acaaaagtat tgtcactgcc
     3001 ccttctcttg ttttttagca tgttttatcg tttgattttt ttaggaataa aattcttgat
     3061 gaacgtaaat ttttggtaat cgtttcgact atagaggtaa ccaaatacac tgaaaacaac
     3121 tgctccaata aaattaacaa ataaatcctt catagtatcc atgattccca cgtctaagta
     3181 accattttgg atgattgttt tatctgtttt accatctgca ttttgacttt caatgattgt
     3241 ccgagtgata tctggaacat gatagacagt gtttccgtct ttacttaact ccacactatt
     3301 gatttgctgg atgatcgtat ctttttgcat atcgaattgc agtaatttat ctgctgaaaa
     3361 ttccacaaac tcccacataa caccaactgt catcgaaaaa cagaaggaaa caactgctag
     3421 taataaagga gtcaagttca tggtttttgt atttttattg agcaaataaa caagggaaaa
     3481 gccgacaccc ccagctaaaa atccgctgaa tgcatgtaga aaagtatccc acattgaaaa
     3541 atagccataa aaatcactta actctcctaa aactgttgaa ctaaaaataa aagataacaa
     3601 aatgatttct agcatatttg gaatctgtat ctttaatatc ttttccagaa aataagggat
     3661 ttcaaataaa attaatgtca gtaataaaag cattgtattt ccccagtgtt ggttccagac
     3721 ctgatccact agcataataa cgacgatgat acgtaataaa atatagattc cgtttgtgat
     3781 tctacctgca gtttttgtac tgttcgtaaa aaaggttttc aaatgattca taaaataact
     3841 ccttcatgta tatccttaat tatactaaga agcgtgtgtt taccaaagct atatgactta
     3901 aagaaaaaca gagttgatat tgtgaaaaaa atcacttaat atagtataag gagaaaaggg
     3961 ggatacaaat gaaaaaatta gttgctggtt tattaacagc cgttgcactt cttgctatga
     4021 gcgcatgcgg cgcagatcag aaaaatacag cgcagacaag ttctagtacg aaggaatctg
     4081 ccgaagtatc atcaggcgct tctgaacaag tatatacaga tccaaaagaa atgaaagaat
     4141 cttatgatgt cgtgattatt ggagctggtg gtgcagggat ggcagcagct atcgaagcaa
     4201 aagatgctgg gttgaatcca gtaattttgg aaaagatgcc tgttgccgga ggaaacacat
     4261 ctaaatcatc aagcggtatg aatgcttcag aaacaaaatt tcaaaaagaa gaaggaatca
     4321 aagactcgaa tgatgccttc tatgaagaaa cgctaaaagg tggtggagga acgaatgata
     4381 aagaaatgct tcgatacttt gtcgatcact ctgctgatgc ggtcgattgg ctagatcaaa
     4441 acggtatcaa actggacaac ttaacgatca ctggagggat gagtgaaaag aggacacatc
     4501 gtccgtctga tggctcggct attggtggat acttagtgga ggggttattg aataacgtcc
     4561 atgagcggga aatccctatt tttgtcaacg cagatgtgac agacattaag aaaaatgggg
     4621 aaacggtcaa tgaagtgact gtacatgttc aaggagaaga accaaaagag gtcaccggaa
     4681 aagcaatcgt agttaccaca ggcggttttg gtgccagcaa agaatttatt gaaaaatatc
     4741 gtcccgattt agctgattat attacgacaa atcaagaagg atcaactgga gatggtatca
     4801 ccatgattga aaaattaggt ggacaaaccg ttgatatgga taaaatacaa attcatccaa
     4861 ctgtgcagca ggatgagggg gtcttgattg gtgaggttgt tcgcggagaa ggagcaatct
     4921 tggtcgatca agaggggaaa agatttgtca atgaaatgga tacaagggat aaagtatctg
     4981 cagcaattac agcattgcct gaaaaatcag cttatttgat ttttgaccaa ggcgtgcgtg
     5041 atcgtgccac agctattgaa ttttatgacc aaaaaggata tgtcacaact ggaaagacaa
     5101 tggaagaatt agcagaaaaa atcgatttac caaaagaaac actagcaaaa acagttgatg
     5161 gatggaatac ggatgttgcg gagaaaaaag atgctcaatt caaccgtgcc acagccatgg
     5221 aacatgactt atcgtctccg aattattatg cgatcaaaat cgcaccagga atccattaca
     5281 cgatgggcgg tgtgaaaatc aatacgaaca ctgaagtatt agataaagaa aaccagccaa
     5341 ttagggggtt atatgctgct ggtgaagtca caggtggctt acatggaaac aaccggatcg
     5401 gtggaaattc agttgcggag atcattattt ttgggcgaca agcgggcata caagcagctc
     5461 gatttgcttc ggaaaatgaa tgaaatagaa cgtaaataaa aagaggttgt gaaatcagcg
     5521 ttttgagcta ataccgaggg tcagctgatt gaacactgtt tagtgaagag gttgtgaaaa
     5581 agctgccctg catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttaac
     5641 ttggttggac ttattaccgc agatgcaagc ttttgaacac cgtttattcg gaaaaagagc
     5701 gtgggacaaa agtaaagaac acttttgtct cacgctctaa acacgtataa acggcggaag
     5761 cagaagaaat tccttcggaa ataagctgaa attcacaaaa atttgaaaag caattttcgt
     5821 gaatttcttc ttatttcttg gagttaaacg cttctgtccc agcctctttt ttgatcagca
     5881 tgattttatt cagttatctt caaaatgatt tttccgatgt ttttgtttgc ttccatatat
     5941 tcatgcgctt gtttgactgc gctgaattgg aatgtacggt caatgattgg ccgaatcttg
     6001 ccattttcta gaaaaggccc agctttttgc ataaaagttt gtgcgagctc tgctttatac
     6061 tgatcacttc taggtgtcaa taatgtacca agcagttgga cacgtttccc aatcaataca
     6121 ccaaggtcta tctcaggcac gatggtccca cctagcatac caatcaagac ccaacgtcca
     6181 tcaacggcta tagaagctaa attcttttcc cagtaagaag cgccgatgaa atccaaaata
     6241 acatcgactc cccgaccttc agtgattttt cgtacctctt cttgaaagtc ttgtttttta
     6301 tagttgatca attcatctgc accaagttct ttacaaaagg cgagtttttc ttctgatcct
     6361 gcagtaacga tgattttcgc gtgagaaagc tgtctagcta attggatcgc tgctgttccc
     6421 acaccacttg ctcctgcatg gatcaagaca gtttcgcctt cttgtaattt tccaagccag
     6481 taaagtgttt gataagcagt caaaaaaact tctgagattc cagcagcaga aacatagtct
     6541 agcgtatcag ggagaaggat tgcacgatcg gcaggcatca cagcatattc ggcataacca
     6601 cctagattga ctaatccgta tacttttgtc ccaggagtaa aagtggagat atcactttta
     6661 ttctcaacta cctctccagc tacttcgact cccaaaatag ggtagggagg tttcaaagag
     6721 actgattctc ttttcataat atctgttcga ttgacagctg ctgtatggac tttgatcagt
     6781 aattcgcctt gttttggttt aggaacaggc acttcaattt gttctaatac atctacagaa
     6841 ccaggatgct tgattgaaat ggcacgcatg gatctattcc tcctttgccc attcttggaa
     6901 tgctgtattc aactctttgc taccttcaga aagtactaga gtcgtacgag aaatatccgt
     6961 ttcttccact agagcggcaa gtacagcagc aactgtagag cgagtgatcg tttttgatgc
     7021 cttctcatta ggcttagtta attgaatgga agtaacttct tcatcgttag tcaatgtgac
     7081 tggttgaaga atgacaaaat ctaagttagt tcgtttcagc cattcatctg cataatgttt
     7141 agtaatataa taatctgtca tggactcagg ccattttgct ggttcatctg cataaacagc
     7201 actgaccatc agatagcgag agacatgcgc attttcagct gcgatcactg ttttgattgc
     7261 gccatccaag tctacttgca gaagattctt tccttgagag ccggcagcaa aaatcaatac
     7321 atcgatgcct ttgaatgctt cggtcatttt ttccacggac caagttaaat caaaagagac
     7381 atacgaaaca ttctcttttt ttactaatgt ttgggaagca acatctctca cccctgcaaa
     7441 aatttcatgg gaacttggag ctaaatcttt tatcaggtgt cggccaattt gtccgtttgc
     7501 acctacaaca aaaattttca tttggatcat cctttcgacg tcaaatcttt ccattcaata
     7561 gtaacaccaa aagagaaaaa aatcagagat cggctacgat gactatcagt tagtaagaga
     7621 agggtgcttg aagtatctta acaagacatt gcatactgct gcagtcgcaa gacctgcgac
     7681 gattccttca ggtataccac ttgtaaaaat aaccgctaga atagctgaat aaacagcatt
     7741 taaatttgtt ccgatgactt tggcataatc ttgctggaat aaaaagtaga tcatattcat
     7801 cactaaaatc gtattggtca atgaaccgga aagtccagct aagaataaag aaacggaatc
     7861 tgctttttgt ttcattagtt tgcgcagacc tttataaacg aaataaggaa ccaccccaat
     7921 caagatgcga ggaataaacg cgatcagcaa ggctttccag cttccatgtt ctgttccgat
     7981 gactgggata aacggagaaa agacaaaaga caaaggtgtt tggataactg tgctacggat
     8041 catgctgatc agtccaaatg taccgccaag aaaagcacct agtcttggtc ctaaaacgat
     8101 cgaagcaatg attacaggaa tatgcatggt tgttgcattg attggaccga tagggataaa
     8161 acctaaaggc gtaacagcta ataaaatcaa aatagctaaa aacatcgcag ttaatgtaaa
     8221 gttttttgta tttttcataa gtactccttt tttctaagca tttctttcat taagagtcag
     8281 catgacctgt tcgatgatcg tctgaatatc agctaaggca ccttttccaa aatctccaca
     8341 agctaaaaga gattctcttg gttcaatttc ctgatagccg acagatctca atgtttccag
     8401 attacgctga gtgatcgggt tttgatacat attcgtgttc atggcagggg caatcaattt
     8461 tggtgttccc actggaagcg ccattgcgac tgttgaaaga agatcgtctg caatgccgtt
     8521 tgctagcttg ccgataatgt ttgctgtagc aggcgcgatg agaaacaagt cagcttgttt
     8581 tgctagttcg atatgattga ttacctgcgg atttgattct tgcatgacgt ctgtatggac
     8641 tgcgcgcttc gacagagatt gcaaggttaa tggcgtgata aaatgtgtgc tgcttttaga
     8701 cataatcaca tctacctggg cacctaattt gacgaattga cttgtaagat cagcgctttt
     8761 gtaagcagaa atacttccag taacgcctag taagatcttt ttcattttga ttcctccagt
     8821 ctaattttct cagtaatcaa tgcagcaatc tcagatttac tttgagcttc ttccactgtt
     8881 ccatctttag ataagagata gccgtggtgt gtctcgccat ggatttccgt caaatcattt
     8941 gcgaaaataa aatcagtttt gttatttatc agactatttt ttgcgactgc cagaagagat
     9001 tcctttggta catctactaa tagtttgaaa ccaatgattt ttgcttttgg ctgccattca
     9061 cgtagataag aaatgatttt tggtgttttc ttcaaaacga gcacaagatg ctcggtgtta
     9121 gaagagatct ttgaaacagt ggtatctgtc tgttcatttt ccgcaaacca attgtccagt
     9181 tcttcttgcg ttgaagaagt gggtaggttt tttgccagct gttcttctga aaaactaaaa
     9241 gcaggagtaa aatcactgac tgccatactg tggataatcg catcgtagtg ttcttttttc
     9301 gttagttctt ctaattgtaa aaataagtcc agtgcagatt cgatcgtata aatcgttata
     9361 ttggagtgtc ttttcggttt cagtgcttgt ttcgtagtca cgtaatcgat tgtggtatcc
     9421 ggattggcag ctaaataatc agctaatgct tgccctaatc gtcctgtcga atgatttgta
     9481 atagcacgta cttgatcgat tttttcagtc gttcctccag ctgtgattag aatcttcatt
     9541 tatggtcacc tacatttact agtgttcttc cttggtgtgt tccagcaagt agtttagatg
     9601 ctgtttcagg caattgatcc agagtaatct cttggacgac cagttcatct gcaatctgca
     9661 aatccgccat ctgttgccat aaagaaagac gttgatctat tggtacattg acagaatcaa
     9721 ttccaatcaa ctggatgttt cgcagaataa aaggcaagac agtcgcgttt agtttgattc
     9781 ccccagcatt gccacataaa gctactgcac cgttataaga gatcaatgga agaagactgc
     9841 ttagctgctc gccacctact gtgtcgatga catagtcgat ttgctgtttt cctaaagctt
     9901 ttgttgtctc tggcagaaat tcatcaggtc gtacgacttg caaagcacct agacttttta
     9961 gccatgtgac agactcttct tttctggaaa aggcaatgat tgactggaat cctagtttat
    10021 gtaacagggc tatcgctgta ctgcctacac cgccagaagc accagtaacg acaacttttt
    10081 tatcggaggt cataccttga cggattaaag cgttcacaca caacatagca gtaaaccctg
    10141 ctgtaccaag gatcatcgct tgacgcagcg tcatattttt tggtagagga actaaccagt
    10201 ctcctggtac tttttgatat tggctataac cgcctggatg ggtgacgcca agcccaaaac
    10261 cagtagcaag tacaagatct tcttttgaaa aacgtggatt gttactttgg acgacagttc
    10321 cggataaatc aatccctgga gtcatcggat atgttcgtat cacctgacca gactcgctca
    10381 ttgccaatgc atctttataa ttgacatcag aataggcaat ttttaccaag acttcatttt
    10441 cagccaactc agtaaatggc agatcactga ttgctgtatg gaaaacaggt tcctttatta
    10501 cctgaaaaga tcgaaaagcg ttcattcgtg agacactcct tttaaaattt tcttttatca
    10561 taccataaag cctactcttt tattcttgtt cttccgtaaa tttagacaaa aattaggtga
    10621 aaaataaaga atcaaacaac tagaatttat tccaaaagat aaagaaatat tcagcaaaaa
    10681 aaattttaca aagggttgcc tttttcaata aatttcgtat actaatacga gtggtagtaa
    10741 acaggaagtt tactattaga aaacttcgat tcggaggaaa ttatggaaat tggtgagaag
    10801 ttaagaaatt tgcgcatcca aaagaatttg acacaagaag aactaggcga acgcacagat
    10861 ttgtcaaaag ggtatatttc ccagttggaa cgagatttaa gttcaccatc aatggaaaca
    10921 ttcttttcta ttcttgaagt cttaggtgtg actccagaag aattttttca tcaagaagca
    10981 gcgaatctgc aagtggttta ttcaaaagaa gatcatacgg tttatttcga tgaagaaaac
    11041 gggtatgaat tggaatggct cgtggctgat tcgaatgaaa aagaaatgga gcctgtcttg
    11101 ctgacttttg aaggtgcagg agaatataag acgtttgaac cttcattatc tgaaacgttt
    11161 atttttgtat tagaagggga attagagtta agcttaggag agacggtcta tgtggcaaaa
    11221 gcaggacagt cgatctatta tcaagcgaca aaacaacatc aattaaggaa tcatctcaaa
    11281 aaacgaacaa aagtattgat tgttgcaacg caatcatatt tgtaatatag ggggtaaaaa
    11341 cgtggggaaa ccaatcattt catttgatca agtagtgaaa cgctatgatg atgaaacagt
    11401 attaaaaaaa gtaagttttg agatcgaaca aggaaaattt tatacactgc ttggtccttc
    11461 cggctgtggt aaaacaacga tcctacgtat tatagctgga ttcaccgaag ctacagaagg
    11521 ggacatctat tttgaaggga aacggttgaa tgatttgcca gctaataagc gacaagtaaa
    11581 tacagtcttc caagattatg cactttttcc tcatatgaat gtttttgata acgttgcttt
    11641 tggattgaag atcaagaaaa tgtccaaatc agatatcgaa aagaaggtaa aagatgcttt
    11701 gcgtatggtc cagcttcctg gatacgaaaa acgggagatt agtgaaatgt ctggtggtca
    11761 aagacagcgt gtagcgattg cacgagcaat tgtaaatgaa ccgaaagtat tgctattaga
    11821 tgaaccgtta tcggcgcttg atttgaaact acgtacagat atgcagtatg aactgcggga
    11881 tctgcaacaa cgattaggaa tcacgtttat ttttgttact catgaccaag aagaagcgtt
    11941 ggcaatgagt gatgagattt ttgtcatgaa taaagggaaa atcgtccaaa gtggtacacc
    12001 cgtagatatt tatgatgagc caatcaatca tttcgttgct gattttgttg gggagagcaa
    12061 tatcgtggac ggtgtaatga tcgaagataa tctagttgag tttgttggta agcaatttga
    12121 atgtgtcgat ggcgggatgc gtctaaatga accagttgaa gttgttttac gcccagagga
    12181 tttgacgatc acgacaccag ataaaggaaa actagtcgta acggtcgata ctcagctgtt
    12241 tcgtggtgtc cattatgaaa tcatctgtta tgatgaacag caaaatgaat ggatggtcca
    12301 ttcaacgaaa aaagctaaag aaggaagcaa agtaggattg gcctttgagc cagaagatat
    12361 ccatgtcatg cgtttcaacg agtctgaaga agaattcgat gcacgtcttg acagctacga
    12421 agaatagggg ggacaagaat gaaaacaatg cgcaggatct attccgtccc ttatattttg
    12481 tggctcggtt tattcgtgat cgcgcctgta ttaatgatca tttatcaatc tttttttgat
    12541 atgaatgggc aattcacgct gaataattat ctatcttatt ttacgtcggg gacatcgctt
    12601 tctatgacga tcaattctgt atggtatgca tttttgatca cgtttttcac gctgatcatc
    12661 agttacccga ctgcttattt tttaacaaaa ctgaagcaca agcaattatg gctgatgctg
    12721 attattttgc ctacatgggt gaatctgctg cttaaagctt acgcatttat tgggattttc
    12781 agtgtgcacg gcagcgtgaa tcatttcttt gattttatcg ggatcgggcc gaaacagata
    12841 ttattcacag acttcagttt tctgttcgtg gcaacgtata tcgagattcc atttatgatt
    12901 atgccaattt tcaatgcatt ggaagagatg aatccttctt tgatcagtgc tagtagagat
    12961 ttaggcgcga atagctttga gaccttccga cgagtgattt ttccgttatc attaaatggt
    13021 gtgaaaagtg gtgtccaagc agtatttatt ccttctcttt ctttattcat gctgactcgt
    13081 ctgattggcg gaaatcgggt gatcacttta ggaacggcta tcgaacagca tttcttggtt
    13141 acacaaaact gggggatggg ttctacaatc ggtgtgattt taatcattgc tatgttcatc
    13201 gtgatgctcc tgacaggcga gaagaaaaaa ggaggtcgct cataaatgaa aaaatttaaa
    13261 tggtcgtatc tttatttagg gatcgtcttt ttattcctat atgcaccgat cttctatctg
    13321 attttttatt ccttcaatga aggaggaacg atgaacagct ttacaggatt tacttgggaa
    13381 aattatgaag ctgtttttga agatacacgt ttgatcatta tcgtattgaa tacgttcatg
    13441 ctggctttct tatctgcatt gatcgccacg atcatcggga catttggggc tatgggaatc
    13501 tattacacga aaaaacgacg tgcacggaca gcgttgttga gcatgaataa catcttatta
    13561 gtctctcctg atgttattat cggtgctagt ttcttgattt tctttacact actaggattc
    13621 ggattaggtt ttcagagtgt attgctttcc catattgctt tcagcattcc aatcgtcgtc
    13681 ttgatggtct tgccaaaatt gcaggaaatg aacgattcaa tggtcgatgc ggctagagac
    13741 cttggtgcta ataatttcca agtagtcaaa aatatcattt tgccttatct ttctccagga
    13801 atcatagctg gatattttat ggcatttacc tattctcttg atgattttgc ggttacattt
    13861 ttcgtcacag gaaatggctt tacgacgctc tcagtagaga tctattctcg tgcaagacaa
    13921 ggaatcagtt tagaaatcaa tgcgctaagt gcgttagttt tcttgttctc catgatattg
    13981 gtcattggat actactttat tagtaaagaa aaccgtccaa aacggctgaa gaaaaacaga
    14041 agagtacgcg agggggtggc acggctgcga tgaaaaaatt acaatctctg tttttaggta
    14101 ttctcatcat tattgcggtg ctgctgcttg gtgttcgtca acttgaaaaa acaagtggca
    14161 tgagtggagc aaaggtactt accatctata actggggaga ttatatcgat cctagtttga
    14221 tcacgaaatt tgaaaaagaa tatggataca aagtgaatta tgaaacattt gattctaatg
    14281 aagcgatgtt cacaaaaatc cagcaaggtg ggacaaacta cgacatcgct ataccaagtg
    14341 aatatatgat ccaaaaaatg atcaaagaaa aactagtact tccattagat cattcgaaga
    14401 tcaaaggatt aaataatatt gatccacgat ttttagactt ggattttgat ccagataatc
    14461 agtattcgat tccatatttt tggggaactt tagggatcgt atataacgat aaattctttg
    14521 atgcaaatca aattaagcat tgggatgatt tgtggaagcc ggaattaaaa gacagtttga
    14581 tgctgattga cggtgcacga gaagttatgg ggctttcttt gaatagttta ggctattctt
    14641 tgaatagtaa gaatatggca cagctgacag aagcagcaaa taaattgaat catttaacac
    14701 caaatgtcaa agcaatcgtg gcagatgaga tcaaaatgta tatgatcaat gaagaagcct
    14761 ccgtggcagt gacattttct ggcgaagctg ccgatatgat gtgggaaaat gaacatttac
    14821 attatgtgat cccaccagaa ggatccaatc tttggtttga taatatcgtt atgccaaaaa
    14881 ccgtgaaaaa taaagaaggt gcctatgatt tcatcaactt tatgctagaa ccggaaaatg
    14941 cggcacaaaa tgcagagtat attggttatt ctacaccaaa tgaagaagca aaagcgttat
    15001 tgccaaaaga catttcgtcg gacgaacaat tctatccatc tgatgacacg atctcccatc
    15061 ttgaagtcta caaagatcta ggatcgaaat acctaggcat ctataatgac ctattcttag
    15121 aattcaagat gtataggaga taatggcaaa actcagtaag aatggggact tatcaacgtt
    15181 ctaaagagct aaaaatcgtc ctttttctat ctgagttttc caatcttcta ccaaaagcgg
    15241 atgaaacgcc gctttttttg tgttatttta ttttttctac cacgtttttc taccagagaa
    15301 aagtggacaa aaccattgta aaatagggcc cgagacgggc tagtaaatct aagattgaaa
    15361 aagttacaga aggataaagt aattggaaac tatgcaaat
//
LOCUS       DADVXE010000065        15261 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.066, whole genome shotgun sequence.
ACCESSION   DADVXE010000065 DADVXE010000000
VERSION     DADVXE010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.066"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(42..500)
                     /locus_tag="KB913_002213"
     CDS             complement(42..500)
                     /locus_tag="KB913_002213"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBB6820550.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(671..1816)
                     /locus_tag="KB913_002214"
     CDS             complement(671..1816)
                     /locus_tag="KB913_002214"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBB6820551.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(1829..2746)
                     /locus_tag="KB913_002215"
     CDS             complement(1829..2746)
                     /locus_tag="KB913_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBB6820552.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3174..3737
                     /gene="efp"
                     /locus_tag="KB913_002216"
     CDS             3174..3737
                     /gene="efp"
                     /locus_tag="KB913_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBB6820553.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            3838..4008
                     /locus_tag="KB913_002217"
     CDS             3838..4008
                     /locus_tag="KB913_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820554.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            4223..5482
                     /gene="lysA"
                     /locus_tag="KB913_002218"
     CDS             4223..5482
                     /gene="lysA"
                     /locus_tag="KB913_002218"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBB6820555.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            5469..6269
                     /gene="dapF"
                     /locus_tag="KB913_002219"
     CDS             5469..6269
                     /gene="dapF"
                     /locus_tag="KB913_002219"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBB6820556.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6272..7153
                     /locus_tag="KB913_002220"
     CDS             6272..7153
                     /locus_tag="KB913_002220"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBB6820557.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7150..7866
                     /locus_tag="KB913_002221"
     CDS             7150..7866
                     /locus_tag="KB913_002221"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBB6820558.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            7872..8567
                     /gene="dapD"
                     /locus_tag="KB913_002222"
     CDS             7872..8567
                     /gene="dapD"
                     /locus_tag="KB913_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBB6820559.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            8583..9584
                     /locus_tag="KB913_002223"
     CDS             8583..9584
                     /locus_tag="KB913_002223"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBB6820560.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            9581..10942
                     /locus_tag="KB913_002224"
     CDS             9581..10942
                     /locus_tag="KB913_002224"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBB6820561.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            10902..12053
                     /locus_tag="KB913_002225"
     CDS             10902..12053
                     /locus_tag="KB913_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBB6820562.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12028..13197
                     /locus_tag="KB913_002226"
     CDS             12028..13197
                     /locus_tag="KB913_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6820563.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            13372..14751
                     /locus_tag="KB913_002227"
     CDS             13372..14751
                     /locus_tag="KB913_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6820564.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15032..15261
                     /locus_tag="KB913_002228"
                     /pseudo
     CDS             15032..15261
                     /locus_tag="KB913_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4996 a         2709 c         3274 g         4282 t
ORIGIN      
        1 agatagctat attgcttctc atctttacgt tcttttagaa actatgcttc tacttcagac
       61 cattcatcgc gttttgctaa aaattcacga gccaaagctt gtgcaccttc tagtgtatgg
      121 ctggcagccc agccacattg tgtttcattg cttgcaggta cttcagtagc ttcaagaaca
      181 tctttcattg ttgcttcaag aacatctaaa atgtcttcgt agctttcatg attcaataca
      241 gtcaagtaaa agcctgtttg gcatcccatt ggagaccagt ctacgatgta atctgcgtga
      301 ttgcggatta gttcggcagt caagtgctca agtgaatgta gacttggcat gtccatgtgt
      361 tctttatttg gttgtttaaa gcggacgtcg tatttaatga tgacatcgcc atgcgcaccc
      421 gtttttcgat cagctacacg tacataaggt gctttgactt ttgtatggtc aagattaaaa
      481 ctttcgacat tcattctcat ttgtaagact cctatctgtt tgttcattcg ttttgatgct
      541 tttcactaaa gaattattta gtgaaattta caaaaacgtc tttctacttg attctaacac
      601 ttatcgtttc caaggtgtag caatctgaaa tattttttag atttttctgc taagtcgttt
      661 attgggactt ctagttcttg attctgtcaa atgcctgagc taaatcgttt atgagatcct
      721 gaccatactc aattcctaca gaaagacgga tcaagccgtc ctttatgcca gcctcttctc
      781 gtttttcttt tggaatagac gcatgagtca tgacagaagg aatttccact aaactttcta
      841 cgccacctaa actttctgct aaagtaaata gttggagtga ttcaacaaat ggaatagcag
      901 attcttcatt ttttaaagta aaagaaatca ttccgctaaa gccgctcatc tgctgcttag
      961 caactccatg gagttcatga tcgggtaatc ctggatagta gaccttttct actgctggat
     1021 gagaaaatag aaaatcagct accacaaaag catttttttg atgttcctcc atacgaacac
     1081 ttagtgtctt gattccgcgc tgaagtaacc agctatcttg gggaccaagt acggctccga
     1141 tagcattttg gtaaaatccg atctgatcgg ctagatcttt atggttagaa gtcactaaac
     1201 cagctactac atcgctgtgt ccgcctagat atttggtacc gctatggaca acgatatcag
     1261 aaccgagatc taaaggtctt tgaaaataag gagtagcaaa tgtattgtca gcaataacta
     1321 tcaatccatg ttgatgagcc agagtggcac ttttttctaa atcagtaatc tttagaagcg
     1381 gattgctagg tgtttcaaga taaagtgctt ttgtattggg tttgatggat tgttctattt
     1441 tatcaagatt actcgtatct atgatcgtgt actcgagacc atttttagta agaactttgt
     1501 caaatagacg gaatgttcct ccatagacat catctcctaa taagatatga tcgccagctt
     1561 gaaaaagaga aaaaacggca tgaatcccag aaagaccaga agaaaaagcg aatcctcgaa
     1621 caccgccttc caaatcagca atcagttctt ccaatgcaaa acgagtagga ttaccagatc
     1681 ttgaatattc atattgttta ggctggccga cgccatcttg ccgataagtg gatgtttgat
     1741 aaataggtac actgacagct cctgttgtgg gatcttcact gatgcctccg tggatcaatt
     1801 ttgtttgaat gtgcatgttt ctttcctcct ataagtaaat gttttttgat aaatagcggt
     1861 ctgctgcgtc tggaaaaatc gtaacgacac gatgaccagg tggtaaacga cgaatttctc
     1921 ttaatgctgc tgcaaaagcc gcaccactcg aacttccaac taatagtcct tgttctcgtg
     1981 ctaactgcct agtatagtta aacccttcta catcagagat tgtctcgatc tgattgattg
     2041 aaaggggaga aagaaacggc ggaatgaatt ctacaccgat accctcaatt tcgtgagggg
     2101 ctggatcacc accatttaac acagagccct ctggttctac accgattatt cgaatgtcgg
     2161 gatatttttc tttcaaaaag gtagaagttc cagcaaaggt tccaccactc ccaattcctg
     2221 ctacaaaact atggatattt tctttgattt catgaaagat ttctggccct aacgtatgat
     2281 agtaagcagc aggattatct ttattttcaa attgaagagg cagatagctg tttgatatct
     2341 cctctgcaag ttttttactt ttgctgatgg caccgatgat tccttgctca ctaggagaat
     2401 ggatgatctt tgctcccaat gctttcatca attgttgttt ttctaagcta aacttctctg
     2461 gaacaacaaa aaccgttctt aatttgtatg tgagtgcggc cagagcgatc ccaattcctg
     2521 tatttccggc agttggttcg atgatcgtcg ttttttcatt gatttttcct tgggcaaatc
     2581 cttctttgat caaataactg cccaatctat ctttgatact tcctccagga tttaaatatt
     2641 ctagttttgc ataaatagca gaacctttag gcatagaata gtgctgattg tcaaagcgat
     2701 aaagcggtgt ggaaccaata gcttctgtaa ttgtcgagat aatcatgtgg gcctcctaaa
     2761 aaaagataat aaaaaaagga gctgactatt aaatcagctc cttgaaagac atagagaaaa
     2821 attgagtaga taaaaagata agttacctgg tactcattct atgaagggca attaatagac
     2881 atgacaaata gtatgctgct tttatgcacc atacaacagc aacgattcaa ttgtttttgg
     2941 ttgctgactg tcatgtgtat ccctccaagt aaaattttta ttaacgatag catgaaaaaa
     3001 aataaaagtc aaaggcttga aagaaaaaaa tatttcgata gcatcgttta cccgtgttta
     3061 tttttctgac aaataggcat gagaccttaa aagatagaga atactctagt tttctggccg
     3121 gttgtctgat acaataaagt tgattatgat aaagaaaaga aggagcaaaa ataatgatct
     3181 cagcaagtga tttaagagcc ggtatgactt tcgtacaaga cggcaaactg attaaagttc
     3241 tggatgcaag ccaccataaa cctggtaaag gaaatacagt tatgcgtatg aaactgaaag
     3301 atgtccgttc aggtgcaaca tacgacacaa cgttcagacc agaagaaaaa tttgaaaaag
     3361 cacatatcga cacaaaacct gtacaatatt tgtacacgat ggatgataca gctttcttca
     3421 tggatttgga aacatatgag caatatgaaa ttcctgtaga aacagtagaa gaagaaatga
     3481 aatatatcct agaaaacatg gaagtaaaaa tccaattttt cggtagcgaa gtcatcggcg
     3541 ttcaattacc aacaactgtc gtattacgtg ttgtggaaac acaaccttcc atcaaaggtg
     3601 caacagtcac tggttcaggt aagccagcga caatggaaac tggcttagta gtcaatgttc
     3661 ctgacttcat cgaaacagat gaattgttgg aaatcaatac agcagaaggt tcttatgtaa
     3721 aacgtgcgtc aaaataattc gctaacggat tgataagaat ttgaaaacag agcttgacct
     3781 cttgaaaggc agatcatcgg atctgccttt caagaggttt tttgtggaat cagcaaattg
     3841 aaaaataaaa aagtatttga ttttatttat attttgaaag atgaatggca aaagctagag
     3901 aaagaaaaaa ctgcacttat ttatgaagaa attgaaatga ttcataaaat tgaaaatatc
     3961 cgaactattc cgaactatat tgaagcgaaa atattttttc atcactaaat agtgttgaat
     4021 ttatgttttt atgtataaat agcttctaat agttcgggta ttttgttttt ataaccattt
     4081 ttattcttat ttttaaaaaa atatttcgaa atatactaga caattcagaa aattttgttt
     4141 aatattattc caataaaatt caaatcttta tcaaatgaaa ttccaataaa aacggaaaaa
     4201 aagtgaaaag aggaatgaaa aaatgacaga attgataatt ggcggagtca cagcaagcac
     4261 attggcagaa aagtataaga cacctctgta tgtgtatgat gaagaaaaga tgagacaaac
     4321 gatgctgtca ttcaagcgag gctttgtatc gaaacgtttt gatacaaaag tgctttacgc
     4381 ctctaaagca ttccaaacga ttgagatgct gcatttagtt cgtgaatatg gattcgggct
     4441 agatgttgtc agtggtgggg aaatctatac cgctttgcaa gctgattttc ctagagatac
     4501 tatctacttc catggtaaca acaagacgcc agaggaactg atctatgcac ttgaaaatga
     4561 tttgttgcat attgttgccg ataatttgat ggaagttgaa ttattagcag aattaagcca
     4621 acgctattta aaaaaaatct gtatcatgct tcggttgaat gtcggagtag aagcacatac
     4681 tcatgaatat atcgtcactg cgcatattga ttcaaaattc ggcatgagct atgaaagtaa
     4741 agagtgccaa caagcccttc agttgataaa agaaagcagc tatctagagt tagaaggatt
     4801 tcatgctcat atcgggtcac aaatttttga tgttactgct tggttagctg aaatcgacaa
     4861 attgacgaat tacttaaccg attttgacca acctctttcc ttgaatcttg gcggagggtt
     4921 tgggattcgt tatacacaaa atgatcagcc gatcccagtc gaagaggcac taaaaaaact
     4981 gattgaatat acggaagaag ctttggaaaa acgaaaactg accattcgtc aattactgat
     5041 cgaaccgggt agaagtattg ttggagaagc tggtacaaca ctatacacga ttggtttcat
     5101 caaaaagaca ccacataaaa aatattactt tgtagatggc gggatgacag ataatatccg
     5161 tccagctctg tatcaggcag aatacgattg tgatttagca gcaaaactgt cggaagaaaa
     5221 aacagagaaa gtgacgattg caggaaaaat gtgtgaatca ggcgatgtgg taattaaaga
     5281 agcttatttg ccgaaagcag aatcgggtga tcttttagct gtttattcca cgggagctta
     5341 tggatactcg atgagcagca actacaatcg agcgacacga ccagcagttg tttttgtcaa
     5401 taatggccaa tcaagactga ttgttcgcag acaagcattt tctgatctac taagggggga
     5461 agtttcctat gatccttcat aaatataatg gctgcggaaa tgattttatc ttattagatt
     5521 acgcagaaga cacagattat agtcaattag ccgcttcttt atgcacaaaa gaaaaatatg
     5581 atatagacgg attgatcgcc gtaaaaatcg atccgttgga aatgatctat tacaacaaag
     5641 atggcagccg cgcgccgatg tgcggaaatg gcattcgctg ttttgctcga tacgtaaatg
     5701 atcagaacat gatgaatgaa caggaattca acgtagagac attagcaggc acaagaaaaa
     5761 ttacggtgtt ggatccctca cctttttatt gcagcgtaga tatgggagtg ccagatgatt
     5821 ctccggaaaa aatcaaagct aatcaaactt atccaataaa aaaccaggaa atagagatca
     5881 atggtgaaaa agtaacgatc actagtttat ttttaggaac gattcatacc gttgtttttg
     5941 ttgaaaatgc gcgtgaggaa gtctggagaa aaagaggtga actgatctgt catcatcctt
     6001 tgttcaaaga aaaaaccaat gtcaactttg tagaagtagt caatgaacaa gaattgatcg
     6061 tccgtaccta tgaaagagga gtaggttgga cacttgcttg cggtacaggt tgctgtgcct
     6121 cttatgtggt tgctaaggaa actgggaaaa tttcagcaga tcaggtagtt gttcacttgg
     6181 aacaaggaga cttgatgatc tctggtgagg atgcgataca aatggctggc ccagcagttc
     6241 atgaatggac aagaatattg gaggaatgaa gatgataaaa ggttcgatcg tggcgctgat
     6301 cacgccgatg aatgaagagg gatcagtaga ttatgctggt ttggaaaaat tgatccaatt
     6361 ccatttagat gaacaaacag atggattatt agttttaggt acaacaggag aatcttctac
     6421 gctcacacaa tctgaggagg agcagatcct tcaactgaca gtaaagaaag tggctggccg
     6481 tgtgccggtg attgcaggag ctggaacgaa taatacgaaa gaaacgattg aaaaagcgaa
     6541 gcattttgct tctttggggg cagacgcact tttggtcatc accccttact acaacaaaac
     6601 aagtgatgca ggactagctg ctcattttac agcaattgca gaagcctcac cgattccgct
     6661 tattttgtat aatgttcctt ctagaacagg catgtcgatt ccaatccatg tattagtaaa
     6721 tttagcagaa catcctaata tcattggttt gaaagaagcc tcaggagata tggcttatgt
     6781 gatggatgcc gctcggttga ttggagaaga attcttcctt tacagtggaa atgatgattt
     6841 gatcctacca gtaatgagtg taggaggaag cggtgtaata agtgtatggg cgaatatcca
     6901 acctaaaata gtccatgaat tagtaaaaga tacgcaggac ggaagatggc agcaagcaaa
     6961 agaaaagcaa ttaaatgcac ttgaactgat ccatgccttg ttcagtgaga ccaatcctat
     7021 tcctgtcaaa gcagccatgt cattattaga cttaccttcc ggacctctac gcctgccttt
     7081 agtttctctt tcaaaagaga aaaagaaaca attagctcag cttttgttaa aagaaaggac
     7141 ggttgaaaaa tgaaaatcgg actgattggc agtggacaga tgggaaatag agtcgaagaa
     7201 gttgcacaag aaagaggaga tacggtcctt cttttacgga cggcacctaa agaagcaact
     7261 acgcttgctt ttacggaact gccagaactg cttattgatt tttctcatcc agataattta
     7321 gagaaaatcc tttcgtatag cttatcatat caacttccgt tagtcattgg cacgacaggt
     7381 tatacacaat cacagttcca agaaataaaa gaacatgcca aacatgtacc tgtgatgtat
     7441 agtgctaatt tttcgttcgg catcatggtg atgaatcaac taatcaagca agcagctgca
     7501 atgttgcaag gctggcagat cgaactgatt gaaaaacatc atagtcgtaa aaaagatgca
     7561 ccatctggta ctgcaaatat gctgcttcaa acaatccaag aagtgcaaaa gctgcagccc
     7621 gtatacaact ggcaagggaa aaaaagagaa gaaaaccaaa ttggtgtaca cagtattcgt
     7681 gcaggttctt tacctggtga acatgatgta ttgtttgctg ctactgatga aatatttacg
     7741 atcaaacatg aatctttttc taatcgaatc tttgctgcag gcgcagtaga agcagcggac
     7801 tggttgaaag atcagtcacc aggttattac aaattagaag atttattaat ggacaaaggg
     7861 gtgtaaaaaa cgtggaagct caagaaatca tccgctacat tcaaacggca tctaaaaaga
     7921 cgcctgtgaa agtctatctg aatgtaaccg agccaatcga atttaaagaa agtaaagttt
     7981 ttggtgaagg aagcagcttc gttgtttttg gtgactatga gacgattgct ccggttttag
     8041 aagctgaatc agaaaaaatc attgaaatcg aaatcgaaac tgctgcaaga tacagcgcag
     8101 ttcctttgct agatattaaa aaaattaatg ctcgtatcga accaggtgct attatcagag
     8161 atcaagtgtc aatcggcaac aatgccgtga tcatgatggg agcgattatc aatattggtg
     8221 cagtaatcgg tgaaaacacg atgattgata tgggtgctgt cttaggtgga cgagcgacag
     8281 tgggcaaaaa ctgccatatt ggtgcaggag ctgtcttagc aggtgtgatc gaaccagcat
     8341 cggccaaacc ggttatcgta gaagacggcg tactggtagg tgcgaatgca gtgattgttg
     8401 aaggtgtcca tatcggaaaa gatgcagtcg tggcagcagg agcagtggtt ttagaagatg
     8461 tggcagcaga aactgttgtc ggtggaatac ctgcacgtgt attaaaaata agtgatgatc
     8521 agacaaaaga aaatacagca ttgattgctg cgttacgcga attatagagg agatggagaa
     8581 aaatgcgcga aatagatacc tgtattgtgg gggcaaccgg attagtcggc caaacgatgc
     8641 tcaaagtgtt agaagaatat gattttccag taggacgatt gaaattatta gcttcaaaac
     8701 gttcagccgg taaagtttgt gtattcaaga aaaagaaaca cactgtacag gaattgacag
     8761 aaacttcatt tgaaggatat gatttagcgc tattttctgc aggtgcttct gtatccaaag
     8821 agtttgcgcc aatcgcacga agtcagggac tatttgtcat agataattcc tcagcatggc
     8881 gggaagattc ggatattcca ttaatcgttc cagaggtcaa tctggaagac tatacattga
     8941 atcggctgat tgcaaatcca aattgttcaa ccattcaagc ggtacttccg cttaaagctt
     9001 tacaagaagc ctttggtatc cagcgagtca attattcgac ctatcaagca gtttctggtt
     9061 ccgggcaaaa aggcattgaa gatcttcatc gtacgcaaaa tgacgaggaa ccagttttgt
     9121 atccttataa tattagccaa acggtgattc cggaaatcga tcagcctttg gaaaatgggt
     9181 atacaaaaga agaacagaaa atgataaatg agacccgtaa gattctgcat cagcctgctt
     9241 tgccagtatc agcaacctgc gtacgtgtgc caatcgaaaa tggacatgga gtctctgtgg
     9301 cagttcaact gcaaaaagag tttacgacgg aagaaattag agagtgtctc agccagtttc
     9361 cagggattca attagaagat gatctagcag cacataaata tccgacgagc attcttgcta
     9421 gaggaacaga tatggtttat gttgggagga tcagaaaaga cacttcttta gagaacggat
     9481 tgttgttcta tacgactgcc gataacatac gcaaaggagc cgctgcgaat gccgtacaga
     9541 ttgctgcagc tttaatgcag aaaatagcgg aggtggcaag atgagtaata cgctgaaagt
     9601 agcgaaattc ggcggaacat cgatgtctca tgaagagcaa ttcaaaaaag tccgtacaat
     9661 tgttctttca gatcccaatc gccaagtgat cgttgtttct gctttaggca aacgtacgtc
     9721 agatgatgac aaagtaacag acttacttta tttgatttat gcttaccttc agcatcatgt
     9781 tgattggaca cccctttgga aaaggatttg tgatcgtttc attcaagtaa gagatgttct
     9841 tgccctgcag ttacctattg aagatgaact agcacgcata cagaaacaac tggaagacga
     9901 aaagataact gaagattatt tagtaagtag aggtgaatat ctgactgctc aactgatggc
     9961 tgagtatctt ggttaccagt ttattgacgc aaaagacctg attttctttg actatgatgg
    10021 gaaaatcgat caggaaaaaa cagcacagga aatcacaaaa gcatttaaaa gatatccgaa
    10081 aatggttgtt ccagggtttt acggggcgaa ccctgcagga aaagaaaaat tattgggccg
    10141 tgggggaagc gacattaccg gcgcgatact ggcgaagatg ttgcaagcgg aaagttatga
    10201 gaattggacg gatgtttcag gaatcatgat ggctgatccg cgaatcatcg atcatcctaa
    10261 aatcatcgag gaaatctctt ttagagaact gagagagatg gcttatatgg gggctaacgt
    10321 tcttcatgaa gcagctgttt tcccagttca agaggctgat atccccatcc aaataaaaaa
    10381 taccaatgat cctttcgctc aagggacaaa aatatcgaat cacgaaatag aaaaggaaaa
    10441 tggactgaca ggaatagctg gacgcaagga ttttctttcc atcactttat tcaaacgtca
    10501 tatgtccgat gaaatcgggt ttatctggaa agcaatgagc atttttgcta aacatgagat
    10561 atcaatcgaa catattcctt cagggatcga caatatcgga gtgatcgtct cagcagaagc
    10621 gattgccgat aagttatttc tcatcacgaa agaattaaaa gaaacacttg gcgtggaaga
    10681 aatcgtcgtg atcgaagact tagctttgat ctctgtcgtt gggggtccgc ataaagaatt
    10741 gattggatta tctgggaaag tgttatcgat attgaacaaa ttagaaattc gcacatcgat
    10801 cttatcacaa ggagcacagg agttgaatct gatcatcggt gtaccgaata atcaatatga
    10861 aacagtagtg aagggtatct atgaagggat ggtgaatacg gatgctgaaa gaatatcgaa
    10921 tggcactcca tcaaattcct gaaatcgggt ttcatgaatt caagacaaaa aaatatttat
    10981 atgaacaagt aaaaaacagc gaggccgtta tccatgaaat cggcgaaaca ggactactcc
    11041 tttattttga taatcagcaa gaagaaacga ttgcttttcg aacagatatc gatgcactgc
    11101 cagtcaaaga agaaacgaat ctctcttttg cttctaagca tgaaggttat atgcatgcat
    11161 gtggtcatga cggacatatg gcgatgcttt tagggttgac tgactttata actaaacaca
    11221 ttgaggatct tatttataat gtagtactga tctatcagcc atcagaagaa atttccggtg
    11281 gcgcacaaag cgttattcag tcaggattgt tggataaata tgaagtacaa gcaatatttg
    11341 gctttcatct atggcctgga ctagctaagg gagaagtttt ctctcgacca ggacctttga
    11401 tggcacaaag cagtgaaaca gacattatca ttaaaggcca gtctgcacat attgcttcta
    11461 gtgaaaaagg aatcgatagt ctggaggcag ctgtacgatt tttgaagaat gtttatgatt
    11521 ttgaccggca attaccggca gagtggaatc atctaatgaa atttggccaa atccaaggtg
    11581 gaacgatccg aaatgtttta gctggagaag ttattgtatc cggaagtatc cgttcttaca
    11641 gttcagatat gcaaaattat ttgaagaggg gattagacca tttagcagaa cagtttcact
    11701 ctacagctac tatttctttt cgctataatg acggctatcc agctgtaatc aaccatagag
    11761 gcttatatgc agcactgtta gattcaaaca aactacatga attagatgct ccagttcttc
    11821 aagccgaaga ttttggcata tatacgcaac aatatccatg tgtatttttc tttttaggtg
    11881 tcggtgatac ccctgcttta catgatccga cgttcgattt tgatatggat gttttagaaa
    11941 atggtgtaga atggtacaaa acgattcttt ttacagaaaa tcttcttgta aaaatcgata
    12001 gcagttcaaa agaggagcga gtaaataatg atgaatttat ccaatcgatt tagtcctagg
    12061 ctttctagaa tagaagtatc aaaaatacga caattcgatc agcaaatatc gtcgatacca
    12121 gatgtgatca aactcaccct gggagaaccg gattttccaa ctcctgaaca tgtcaagcaa
    12181 gcaggaatag cagcgattga agaagacttt tctcactata ccggaatgag aggattagag
    12241 gaactgcggg aagcggcttg tatatttcag caacagcgtt atggattaac ttatgatccg
    12301 caaacggaag ttttgacgac agttggtgca acggaagcga ttgcctctgc gttgttatct
    12361 gttttggaag aaggagacaa ggttcttatt ccagcgcctg cttattcagg atatcagcca
    12421 ttagtggaac tagctggtgc tgaattgatc ccgatagata cttctgacac agggtttgtc
    12481 tgtcagccgg aacaatttga acgagcattt gaacaatatg gatcagctgt caaagcagtc
    12541 attttaaact atcctaacaa tcctactggg acgacattgt ctgcaaaaca attgaaagca
    12601 atcgctgagg ttttaaaaaa atatccggta tttgttataa gtgatgaagt atatgctgaa
    12661 ttgacttata gtggaacgca tatgtccata gctacttatc ttccagaaca aacaatcgtg
    12721 ataagcgggt tatccaagtc acatgcgatg actggttggc gagtgggctt tatttttgct
    12781 caaaaagccc ttattgacga actaattaaa gtccatcaat atctggtgac tgccgctaca
    12841 acgatgtcgc aaaaagctgc ggctgaagcg ctaataaatg gggtgaaaga tagcgagaat
    12901 atgaaagagc aatatcaaac acgaagagac tatctggtcc agcaattggc gcctttagga
    12961 tttgaagtga cccagccaaa cggtgcattt tacttgtttt gcaaactccc agctgccatt
    13021 caaactgact cttggcagtt ttgtgtagaa ttagcggaac aggcaaaagt tgcgtgtatc
    13081 ccaggaattg catttggccc agaaggagaa ggttatatcc ggatttctta tgctagcagc
    13141 atggaaaaat tacatgaggc ctgcaaacgg atcaaagact ttttaacaga acagtgattc
    13201 atagatttta tcaaaaaaac aatcgttaat tttgcggtat attctgcaag gagacgattg
    13261 ttttttaaat ttagttcaaa tgaacgcgtt tcttttgatt cataactaat gtaatgttaa
    13321 gtttaaattg tttagaatga ttttaaaaga atattcaagg aggtttcatc aatggaaaaa
    13381 atcaaagttg tcattgtagg tgcatctcat ggagggcatc aatcgatctt ggaactattg
    13441 acacgatacg gtgaaaatgt agatatcacg ctatttgaag caggagacta tatttccttc
    13501 atgtcatgtg gtatggagct gtatttagaa gacaaggtaa cagatgtaaa tgatgtacgt
    13561 aatttcagac cagaaaactt tccgcaatcc aatgttcata ttttaaataa tcacgaagta
    13621 aaaacgatcg atgccgataa aaaaacagta acggttacta gcgcatcaga taacgaaaca
    13681 aaagaatatc cttatgacaa attgattttg agttctggtg tcaaaccaaa caatctgcca
    13741 gtaccaggag cagatctaga aaatgtctac ttgatgcgtg gatacaattg ggcaaccaaa
    13801 atcaaagaaa aattaaatga tccggctatt aaaaaaatcg ctgtcgtagg tgcgggttac
    13861 attgggatcg aagcagcaga agcaagccga aaagctggga aagaagtcgt attgcttgat
    13921 gtgatcgata gacctttagg cacttattta gatgctgaga tgacagatat tttagaacaa
    13981 cacctaaatg aaaacggtat tgaagttttg acaaatgcaa aaatcgaagc ttttactggt
    14041 aacggaaaag ttgaggcaat caaaacaagt gaaaaagaaa tcccagcaga tctagtcatt
    14101 caagctgccg gtgtgaaggc aaatacagaa tggttaaaag ggatcgtcga cttagatgaa
    14161 cgtggctgga tccaaacaaa tgaatacttg caaacgaatc ttccagatgt gtatgcagta
    14221 ggagatgcta cacttgctta ttctatccca gcacgcaaaa aaatgccgat cgctttagcg
    14281 actgttgcac gtagagaagc acgttatgta gtaaaacatc tttttgaaga agtaccaaac
    14341 aaaccgttcg gcggagtcgt aggttcctct gcattaagtg tctttgacta tcattttgca
    14401 gcaagcggat tgaatagctt tacagcagca aaagcaggag tagatgtacg agtgtcttat
    14461 tatgaagata cgttacgacc aaaatatgta ccagaagaac aaggaaatcc aaaagtgtcc
    14521 atccaattat tctcggatcc aatgacccat caattgctag gaggagcagt attatctacc
    14581 tatgatgtta caggtcaagg aaatgtattg gcactagcga tccaaaacaa actgacttta
    14641 gaagaactag cagaagctga cttcttcttc cagccaggct ttgaccgaca atggagcatg
    14701 ttgaatctag ccgctcaaca agcgttagga gaagaaccat ttgtagaata agaaaacgaa
    14761 atatttgaaa agaggttgtg aaaaagctgc cttgcatcaa gtaataagaa cagccaagta
    14821 aaaacagctt cttatgtttt taacttggct ggacttatta ccgcagatgc aagcttttga
    14881 acaccgttta ttttcaaaaa agggactgtg acacgatttg tgtaccgacc cccaaaagtt
    14941 agaccaaaaa atctaacttt tggaggtcgg tattttttat ggttaaatat acttttgaac
    15001 ttaaattaaa gatcgttcat gattatttgg atggcaaagg cgattggacc gtaaaaatcc
    15061 agatcaagag attgaagcgg aaatgcttaa aattcgggag aagcacaagg attatggctg
    15121 tttacggatg accaatgaac taagaaaccg cggtttctct atcaataaaa agaaagttca
    15181 gcgcttgatc aagaagctag gaataaaagt aacggcatac acgcgtaaat cacgtcgcta
    15241 caattcttat cgaggaaaag t
//
LOCUS       DADVXE010000066        15226 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.067, whole genome shotgun sequence.
ACCESSION   DADVXE010000066 DADVXE010000000
VERSION     DADVXE010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.067"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            278..787
                     /locus_tag="KB913_002229"
     CDS             278..787
                     /locus_tag="KB913_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6820565.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="KB913_002230"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="KB913_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBB6820566.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="KB913_002231"
     CDS             2322..3302
                     /locus_tag="KB913_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6820567.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="KB913_002232"
     CDS             3424..4842
                     /locus_tag="KB913_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HBB6820568.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="KB913_002233"
     CDS             4913..6382
                     /locus_tag="KB913_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6820569.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="KB913_002234"
     CDS             6392..6859
                     /locus_tag="KB913_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6820570.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="KB913_002235"
     CDS             6895..7767
                     /locus_tag="KB913_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6820571.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="KB913_002236"
     CDS             7848..10382
                     /locus_tag="KB913_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6820572.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10538..11311
                     /locus_tag="KB913_002237"
     CDS             10538..11311
                     /locus_tag="KB913_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6820573.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="KB913_002238"
     CDS             11304..12095
                     /locus_tag="KB913_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6820574.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="KB913_002239"
     CDS             12105..12596
                     /locus_tag="KB913_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6820575.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="KB913_002240"
     CDS             12614..13024
                     /locus_tag="KB913_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6820576.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="KB913_002241"
     CDS             13028..14428
                     /locus_tag="KB913_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HBB6820577.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="KB913_002242"
     CDS             14451..14825
                     /locus_tag="KB913_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6820578.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5286 a         2133 c         3045 g         4762 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttaaatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcgatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 aatccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt
    15181 tttttatttt gaaaaatttt tagtattttt cgaaaaatgc tcactc
//
LOCUS       DADVXE010000067        15126 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.068, whole genome shotgun sequence.
ACCESSION   DADVXE010000067 DADVXE010000000
VERSION     DADVXE010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.068"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            10..2382
                     /locus_tag="KB913_002243"
     CDS             10..2382
                     /locus_tag="KB913_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820579.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2443..3903
                     /locus_tag="KB913_002244"
     CDS             2443..3903
                     /locus_tag="KB913_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBB6820580.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3914..6118
                     /gene="topB"
                     /locus_tag="KB913_002245"
     CDS             3914..6118
                     /gene="topB"
                     /locus_tag="KB913_002245"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6820581.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6134..6283
                     /locus_tag="KB913_002246"
     CDS             6134..6283
                     /locus_tag="KB913_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820582.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6358..6951
                     /locus_tag="KB913_002247"
     CDS             6358..6951
                     /locus_tag="KB913_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBB6820583.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6964..7863
                     /locus_tag="KB913_002248"
     CDS             6964..7863
                     /locus_tag="KB913_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBB6820584.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7866..8363
                     /gene="ssb"
                     /locus_tag="KB913_002249"
     CDS             7866..8363
                     /gene="ssb"
                     /locus_tag="KB913_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBB6820585.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8729..8989
                     /locus_tag="KB913_002250"
     CDS             8729..8989
                     /locus_tag="KB913_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820586.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9434..9640
                     /locus_tag="KB913_002251"
     CDS             9434..9640
                     /locus_tag="KB913_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBB6820587.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9688..9891
                     /locus_tag="KB913_002252"
     CDS             9688..9891
                     /locus_tag="KB913_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820588.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
     gene            9907..10344
                     /locus_tag="KB913_002253"
     CDS             9907..10344
                     /locus_tag="KB913_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820589.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10337..11044
                     /locus_tag="KB913_002254"
     CDS             10337..11044
                     /locus_tag="KB913_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820590.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11424..11603
                     /locus_tag="KB913_002255"
     CDS             11424..11603
                     /locus_tag="KB913_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820591.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11928..12191
                     /locus_tag="KB913_002256"
     CDS             11928..12191
                     /locus_tag="KB913_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBB6820592.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12185..12535
                     /locus_tag="KB913_002257"
     CDS             12185..12535
                     /locus_tag="KB913_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6820593.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12559..13173)
                     /locus_tag="KB913_002258"
     CDS             complement(12559..13173)
                     /locus_tag="KB913_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6820594.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13487..13909
                     /locus_tag="KB913_002259"
     CDS             13487..13909
                     /locus_tag="KB913_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820595.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            13919..14122
                     /locus_tag="KB913_002260"
     CDS             13919..14122
                     /locus_tag="KB913_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820596.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14333..14917
                     /locus_tag="KB913_002261"
     CDS             14333..14917
                     /locus_tag="KB913_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6820597.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         5565 a         2450 c         3062 g         4049 t
ORIGIN      
        1 ggaaagaaca tggcagaaga aaaagaacca ctagacaata gtcgtttggg aaaatccaaa
       61 agaaaactag tacgattgca aaatgaatta aacgaacaaa ttgaaaagat gtttgaacac
      121 caaaaaatga cgaacggtca accaatgaac gacaagagga atggccgttc atggtttaac
      181 cagcaagaac gaatcgaaaa taaagtccaa agtctgagag aagagatcaa gcaacaagaa
      241 gaatacgtgg aaaagcttga aagacaagaa gagctaaagg aaatgggcta taacaagtac
      301 ggcggactgg atatgacgat cgataatatt ccaagaatca aagaagaaat cgaacgcttt
      361 gaaaaaggtg aatcggcttt ttcagccgcc acgatccgaa aataccaacg gaagttggaa
      421 acattagaac agctgaaaga aaaatcagaa aaaggaaaag aaaatatcct ccctgaagta
      481 caagcgatca ttgacagcgg acgagtgacg caatggaaaa aaaatccaac catttatttt
      541 ttgaaaggct atcgaaaagt tgctttagaa ctgaatgaaa acgggggatt tgaggaatca
      601 aaaaaatacc aagccacgtc ggaagaggaa aaagcagctg ttcgtgaatt acttgaagag
      661 gctagaccaa ctgattctat gaaggagaaa gaaaacgatc atttctatcg agtagaattc
      721 aacgaaaatg atccagaaaa aggattgaaa agttatggtg gggagatcgt aacattcgaa
      781 ttgatcgatc aactcaaaac attggataac caatacgccg cagaagcagg ttattataaa
      841 ttctattttg aggaagtgaa gaacggagaa gtagtcgatc agatccgaat ggatctaggg
      901 gatggcgtca acagtaatca accaatctat ttagagttag caaaattgtg cgaacaagta
      961 cctgagaagg aacaaaaaca atcggtcaaa aatgaacctg tttcgaaaga acaaatgcag
     1021 tcgaaagaaa caaaaacaaa acaaaagggc tatcaaaaac gaacggcaga agagattaaa
     1081 caagaagtta aatccctttc gcaacaggca ctggatgcgg tgaaaaagca tacccattct
     1141 cctgaagacg tcaaagaact tttgaacttt atgtctcgtt ttccagaacg atcctttaga
     1201 aatcaattat tgattgagga acaatttcca ggtgcaacgg cttgtttagg tcgtgccgcg
     1261 ttgaaaaaag aaggaatcta tatcaaaaaa ggggaacaag ggaacaagat ctttgtcaga
     1321 aaaacggtca aagggtttta tgagaaagga cgtggctttg ttcgagaaac agaagctaca
     1381 ccagaagata aaaaacgaat cgaaagtggt caaatcgaag tgatcaaaaa accttactat
     1441 acgattgaaa aagtgtttga tatcacacaa acacagttaa aacctgaaga ctatccgaaa
     1501 atctttccga accgtgtctt tgattttcaa ttggataaaa aaggacagtc agaacttcaa
     1561 gctgggattc aagcggtagc caacaatatt ggaatacaaa ttcgagatat gacagaaagt
     1621 gaagtctatc aaagagaatt aggacaagca cgtggggcgt atgttcgtaa cgaatttact
     1681 ggcgaagaag aaatcgtcat gaatactcga aatactccta cgcagcattt agctacaagt
     1741 attcatgaat tagcccatgc aagaatgcac aaattttcag aattagatac cgcaactaaa
     1801 gaattgcagg cagaaatgac ttcttatatt gtgtgcaaac attttggaat ggacacgtcg
     1861 gagaaagcta ttccttatat tgcagcatgg acgaagaatg gtcagacgtt ggatgataag
     1921 gaagctgcgg aacgtgggaa aatcatgaat gatgtcagcc gtgtcgcaaa tgaattcatt
     1981 caaaccattt ctaatgaaat caatcaatac agagaaagag aaccagagat ccaaccagca
     2041 gaagtgaagc aggagcataa aaatacttta gaaacgccag agaataagaa tattgtgccc
     2101 gttggttcac tttggatcga caagaaagac gggaaagtaa tggaagaaga tacgggtcga
     2161 acgttacatt tgaaggatgc ggcgtttatt gaagatccgc agcataatca agtaatttta
     2221 aaaggaaaaa gttatggaaa agagatccaa acggcgttac cttcagaaga atttgcgcta
     2281 ggaaatccat tccgattttc acttgagaca gtgtcagaag tggcaaaacg aaaaaatgaa
     2341 atctattatg aacaacaatt gtcacaaaaa gaacgtgtat aaaacaagta aaaaagacta
     2401 tctgaaaaac ggatagtctt ttttcttttg ggaggtttta aaatgaccga gaaaaaaatg
     2461 agtcttattg atcgatgtaa acagatcgat atagtggatt ttgctcgaaa caatggaatg
     2521 gctgtagtca ataaaggacg agattatcgc ttagaagacc atgattcatt tgtttttgat
     2581 cgaagaaaac aacgttttta ttggaacagt caaaatatta gtggcgacat tattgaatta
     2641 gctaaacttt ttttcataga caaagagatc caagacccta agcaacaatt taaagcagcc
     2701 actgatttta ttctaaagaa tgaagacaaa acagaacgag tggaaaatct tcattttgaa
     2761 acagaaaagt acaaagatca ccccgttgat tatcaaccac tcacagaaaa aggaaggaat
     2821 tatctgaagg aagaacgaaa actaccagag tggctgattg attatgcaga aaaagaaggg
     2881 ttgattgccg aactaaagcc aaaatatgaa cggcaaaatt tcttagttcg agacgatcgt
     2941 ttagatcatg cggtcgcctt tttatggaaa gatccacaga caaaagagac agtaggggcg
     3001 agttatcaag gaacgttcat tgattatgaa cgttttggtg agagaggcac atataagcat
     3061 atagataaaa attcgacagc gaatcatggc tttaacctaa agatcggtga ccctaagcag
     3121 ataaaatttt ttgagagtag tattgattta cttagctatg ctgcactgaa tcgtgatcag
     3181 ttaaacgata cgtggttagt ctctatggaa gggttaaaac accatgtgat cagtcattat
     3241 tttggtgagg cagtatctga attgagaaag aaacaagcct ttcctcaatc catcgagatt
     3301 tgtgtggata atgaccgtgc aggacatatt ttctacgaaa aagaacaatt aatgggcgca
     3361 gtcgatccat ttacgaatca gaaagtacgt tgtgaacgag gaatcgctaa tgattggcaa
     3421 gtgccaaaag aatacaaaat catttatgaa gaagtcgcaa aagaagaaaa ggtcacacca
     3481 gaagctatta tggccataca caagacagaa aacaatctgc aattaacgaa ccaactggtt
     3541 tccgctcaca aagtaaatgc gttttttggc cagcagcttt ctgttaacga ttcaatagaa
     3601 gccattaatt tgaaagatat ttgtagagaa gtcgcaaaag aattaaaagt ttgtgaacgc
     3661 gtggatggta cgtacgattt tgatcgtttt tatcaagaaa aaggggatat taatgcgcag
     3721 attcttttct cttataaagc agaacaatac tacaaaggct ataaaaatca tgaacatgaa
     3781 tttgtacctg aagtaaaaaa ggactggaac gatcaattga agcatgagat ccagcaacaa
     3841 gaaatcagaa agcaaaaacg tgccatgttg tttcaacaag gcagacaaca agaaagggag
     3901 tgaaatcgtc atgatgaaaa ccgttatttt agcagaaaag ccgtcacaag cgaaagctta
     3961 tgccgatagc ttctctaaag ccactcgaaa agacgggtat tttgaaatcc aagatcgatt
     4021 gtttcctggt gaaactgtga tcacgtatgg ttttggtcat ttagtcgaat tagattcgcc
     4081 cgatatgtac gatgaaaatt ggaaacaatg gtcattagaa catttgccta ttttccctac
     4141 acattatcac tatcatgttc ctaaagataa gaaaaagcaa ttcaaggtgg tgaaacagca
     4201 acttcaatcg gccgacacca ttattattgc gacagatagc gatcgtgaag gggaactgat
     4261 cgcttggacg atcattcaac aagtaggcgc cgatcaagga aaaaccttta aaagactttg
     4321 gatcaactcc ttagaaaaag aagccattta tcagggattc cagcagttac gagacgcaaa
     4381 agagacctat ccaaaatttg aagaagcaca agcacgtcag atcgccgatt ggttaattgg
     4441 gatgaacggt agcccactgt atagtttact cttgcagcaa aaaggcatac caggaagctt
     4501 ttccttaggc agagtccaaa ccccaacgct ttacatgatt tatcaattgc aggaaaagat
     4561 tagaaatttc aagaaagaac cttattttga aggaaaatcc gaagtaatcg ctcaaaatgg
     4621 cgcatttgat gcgaagcttg atccgaatga aacccaagcg acgcaagaag catttgaaga
     4681 ttatttaaaa gaaaaggggg ttcaattggg aaaacagcca ggcatgattc gccaagttga
     4741 aaccgagaaa aaaagcgcgg caagtccacg tcttttttct ctatccagcc ttcagtctaa
     4801 aatgaatcag ctcatgaaag ctagtgccaa agacactttg gaagccatgc aaggcttgta
     4861 tgaagggaaa tatctaagct atccgcgaac ggatacccct tacattacgg aaggggaata
     4921 tgcgtatctg ttggatcact tagacgaata caagcatttt ttgagggctg aagaaatttc
     4981 gactcctatt catacaccga atagtaggta cgtgaacaac aagaaagtcc aggaacatta
     5041 cgcaatcatt cctacaaaaa cagttatgac agaagcgacg tatgaaagtc tgacaccttt
     5101 acaacaagcg atttacgagc aagttttaaa aacgacagtg gcgatgtttg cggaaaaata
     5161 tacctatgaa gaaacaacga tcttgacgca agtccagcag cttcagttaa aggcaatcgg
     5221 aaaagtaccg atagatctag gttggaagaa gttatttggc aaagagagcg acggaaaaga
     5281 gaaggaagaa gagccgctac ttcctaaagt gacaaaagga gaaatggtga cggtagatct
     5341 acaagtcctt gaaaaagaaa ccaagccacc acaaccttat accgaaggta cgttgatcac
     5401 tgcgatgaaa acagctggga aaaccgtgga tagtgaagaa gcgcaatcca tattgaaaga
     5461 agtggaagga atcggtacag aagcgacacg ggcgaatatt attgaaacct tgaaacaaaa
     5521 ggaatatatc aaggtagaga aaaataagct tgtggtgacg aataaagggg ttttgctttg
     5581 ccaagctgtg gaaaaagagc cgctgcttac gagtgccgaa atgaccgcca aatgggaaag
     5641 ctacttgtta aagattggag aacgaaaagg aacacaaacc acttttctag ccaatatcca
     5701 aaagtttgtc tctcacttat tggaagtcgt cccaggacaa atccaatcca ttgattttgg
     5761 atcgacgtta caagaagtga aagcagccag tgaaaagcaa gaagccgcgc gtcatttagg
     5821 aatttgtcca aaatgccagg aacaagaagt cttactctat caaaaggtgg cagcttgtac
     5881 gtctgaagcc tgtgatttta aattatggac aacgattgcc aaaaagaaac tcacagcgac
     5941 acagctgaag gagattattc aaaatagccg aacaagccaa ccagtgaaag ggttaaaagg
     6001 tcagaagggt tcgtttgaag caacgattgt tttaaaagaa gacttcacta caggctttga
     6061 attttctgaa aagaaaaaaa cgaacttcaa gaaaagaaca cgacgcacga caaaataatg
     6121 gagggttaat cttatgcgta atacaacaca caaacaacaa gaaatcgaaa atcaaaaagc
     6181 caaaattcgt tcagaacaag agaaattacg tgccagtaaa agaagacttc agcaattaaa
     6241 gaaccagcaa cggattcaaa aagaaatcga attagatcga tagacattaa ccttgttaca
     6301 aatacactat catgatatat ttaatgtagt gtatttgtaa caaaaggggg gaagtaaatg
     6361 caagagaaac tgaaagaatt gttggctatt cgcgatggaa atttatctat gaaggaagcc
     6421 agaaaattag gaatcgcagc aaccactgta caaagattgg tgaatcaagg aaaattgatc
     6481 aaagttgatc gtggttatta tgtagaggat ggtcatggaa tagatgattt attttggctt
     6541 cagcaacgtt tttccagggg aatcttctct catgaaacga ctttagatat ttaccagctt
     6601 tctacgaata tgccgaaatt cattcactta acttttcccc atggatataa cgttgatcgt
     6661 tcaattacaa aagagcagca gttacaattt catttcgtga agaaagaagt ttatgaacta
     6721 ggaaaagtag agggaacttc ctttcaagga aatcctatta ctatgtatga taaagagcgt
     6781 acactttgtg atatttggaa tccgagatat gaaattgaat atgaaatgaa attagaagca
     6841 ttaaaagagt acatggaaga cccattgaga gatccaagta aattaagaga ttacatgaca
     6901 aaactacatg tagaaaaaga aatgaaatac cacatgcaaa gcttatattg atggaggaaa
     6961 aagatgacac cgacacaatt tgcagcaaaa acaagaaatt tagcaaagag gacaggatta
     7021 aatgcacagt tagtacaacg gcattttatg atggatcgtt taattgaaca aatttctgaa
     7081 tctaagtata aaaatgattt cattttgaaa ggtggctttt tattaggatc aaaatatgga
     7141 atcgatagaa ggacgacaat tgatatcgac acgacattta gaaatagcaa attaactgaa
     7201 gaaaaattga agagtatttt taatgattta actaggaaac ccacgaaaga aggtattgtt
     7261 ttctctattc aaggaatgaa ggaaacaaga gaagccgatt tttatcctgg atttcaaatt
     7321 aaattggtgg ctaatttaga gaaagtacgt gtgccattta aaatggacgt gacaacagga
     7381 gattctattt atcctgaagt agatacacac tatcaccaat taatgtttga agataaaaag
     7441 gtggagattc cagcttatcc aacagcacaa attattgcag aaaagctaag tgctacgttc
     7501 agctttggca cagataattc gagagcaaaa gattactacg acttatttac cattccgaaa
     7561 ctagaaaata tcgatacgaa agagttatac aaaagtgttc gaaatacatt tacaaaacgt
     7621 ggggatacaa aaccgttgtc cttttattat gaaagagaaa tggataagat cataggaaat
     7681 gactatttgg aaaagcagtg ggaaaaatat cgctcagtta acacgtttgc gaattccatt
     7741 tcatttacag atacagtcaa cgaaattgat cacctaatga aaagtgtgat caaaattgaa
     7801 aatcaagaaa gaaaacggca gtttaaaaga tcacaacaaa tgaatcaaga aatggagaga
     7861 taaagatgat caataatgta actttagtag gacgcttaac caaagatcca gatttacgtt
     7921 ataccgcgag tggtactgca gtagcgactt ttaccctagc tgtcaaccga aatttcacga
     7981 atcaaaacgg caatcgagaa gctgatttta ttaactgtgt gatttggcgc aaaccagcag
     8041 aaacaatggt gacattagct aaaaaaggta gcttgattgg tgtagttggg cggattcaaa
     8101 cgcggactta tgacaaccag caaggacaac gtgtgtatgt gacagaagtt gtggccgata
     8161 atttccaact attagaaagc aaagcagcga cagaaagccg tgcgcacgct gatcaatcgt
     8221 ccaccagtcc aagcaccacc acttttgaac aacgggatac agcgacgcct aataacaatg
     8281 gattgaacgc tttacagaat ccatttggga atccatttgg tggacaatca atcgatatta
     8341 gcgatgatga tctaccgttc taagtagcat tttctattgg ttgcatttgc tacggtttat
     8401 gttataattt agtcaacaaa aagaattttc aatctataac caaaaaccac tagctggcgg
     8461 gctagtggtt ttcttttacg tttctattat aagaattaac gggtaggctt actgtctttc
     8521 ttggcaaatt tacaatcaag ccatttgcag atatagtgcg cggctacttc tgccatgatt
     8581 gcaaaaacaa aatcaaaaag aattttcaaa cctataacct cctccccttg ccagattagg
     8641 ccggggtagc agacagcaag actattatag cataattgaa atatccaaat gattggattt
     8701 ttgctataat tttagcgagg tgattgtgat gaacaaatat gttggtttgc ttgataaaat
     8761 ccgagtaata aaaacgcaac cgttattggt tcgctttact ttacaaacga ttcatgaatc
     8821 gattaattgt gtagttgcag atattgaaat tatcgataaa ttgctaatta tggatgatgg
     8881 aaaatacaat attgccgtca caggtcactt caataaacga aatcagctag ttattgctag
     8941 catgtatgtt agaaatcccg atcattttac gcgatcgatg ggcatataaa aaaagaagag
     9001 ttgcaatcct aatgtaggac tgcagctctt tttgttttac atagaaacaa gaaaaatgaa
     9061 aaggcctttt taggaaggcg cgagcgcctt ctcaattgaa aaacctctct cactccaacc
     9121 gccaccgccg ttcgagaaga aaggaagtga acgttgcacg ttcactaaga taaagggtct
     9181 tgcaaagcaa gacaaaatag aaaaaacttc ctctcaccaa aaggttcgtt cctgttcgtt
     9241 atctctttat tgatttgcca gaccggcaac aagttgcctt ttatcaccaa aaagcgacaa
     9301 ggacaagggt aaatggcacg ctgcgcgccc ttgtccttgt cgcttttcgt tgattcattc
     9361 tggccaacaa atcaataaag aaagaactaa cgaaaggaag taaaaccttt cctaagagga
     9421 ggcagaatca atcatgcgaa agaaatttga ttattggggt gttcccttca gcgaattatt
     9481 cccaaactat catgcaccac atactgtcga atgcgattgt ggacaaagag cgaaatgtat
     9541 caaaagctat cgtttgtatc aatgtccaac atgcggaaaa aaatacacct tgtcttatgg
     9601 cgattatatt ttgattgatg agaaaggaaa gaaacgctga tgaaaacata acataaatta
     9661 ttgactgtaa aagaagtcgt tcaaattttg gtggacaaag aagtcatttc tgaaaaagta
     9721 gcagaagctt tacttattcc gcggtactgg acgatagaaa cccctttagt agaggatgca
     9781 ccgactatgc tatttgaaga cctagtgaag attgcaggat atgaactgca ttatcaagaa
     9841 aacatggaaa cttatgaaaa cgaatattgg ttaaccaaat tagagaacta aaaaggagaa
     9901 aaaaatatgg ctcaaaatta ctatgacgaa tttgtcaaat tacctttgga taaaatggca
     9961 caaaaaatgg aggatatgac attcctatac catgagacac gtgttccaaa aaaacattat
    10021 aaggaaagat tgtcggtagc tgtggaagaa atgattgaat caggtgtcga aatgaatctc
    10081 attgcgacgt actatcgaac actggaagaa ctgaaaaaac aaaatgcaaa atggtttttc
    10141 caagccttac tatgcttgga agtaggtgtc aaaccaagca ctattaaacc ttctgaatat
    10201 caagctttag aactaacgta tgggaaattt gtcgaaacga aaaaagccaa gactgtttca
    10261 agtgaatggt tagattattt tgaaaatatc aataagtatg gcgcctatta caccatgaaa
    10321 aaggaggaca acgaaaatga ataaggtgat ttatcaacta acaacggaag atgtgtcaca
    10381 ctttttaaca aacaaagaac atttgaatga agtaatcaga cggattcaaa aagactttag
    10441 ttgtatggaa gaaatgaagt actttattca aagagtcgaa gaacaattgt atttggaaag
    10501 tgaaacgagt caaacgaagg tcacagtcag caataattat ttagacgtgt ataaacatcg
    10561 tcctgaaacg gtaaaaaaag gaacggagct tctacgacta gaaacagaaa aatacatcat
    10621 gaatgtttac ctagaaagga gtgaactggt cgaaaacttt gtcagctgca cgatttgcag
    10681 gaaacactat tactcagaat cagaatatta ttcaattttt gagagcatgg aattaatgga
    10741 agaagaaatg gaagagctaa acagcaaaaa tgcgacgata gacgattatt atcttgtatt
    10801 tactagattt ttgacgtgtg gaacggaatc tatcgtgtta atgggaatgg attatgaact
    10861 cgctgtaccc gaagcatttt tgagggaata tgtagaagaa gtagataacc caggcgacga
    10921 ctggtacacg actttaactg attttttaga tacctacact tacgacgata cagaagaaat
    10981 ccaaaatgaa cttgaccgta aacgaatgcc atatcaacga tttgaaagga aaaaaaggca
    11041 ataatcattt ataccgaaaa gtgagaatgt gtgaaataag aacaaaaacc ttgaaattaa
    11101 gggaatggtt cttatttcgc accaatcgct ccaaccgccc ccgccgctta ggtggtgcga
    11161 aataagcggg caaagcccga taacctaaga gaaagaagga gatccatatg aataaaatca
    11221 ttcctctgtt gttcgtactg tgtattggcg agatacttat gcgtcatggt gcagctgtac
    11281 atttaaactt cgtagtattc ttaggaatac tagtattttg tttgattttt tggcgctttg
    11341 tgttagccct tgtgagtcta ctattcaagt tgattgcagc catatttttc atagggttat
    11401 ttcgatgaaa ggagagagta ctaatgccaa ttgcaatagg aaataaacgg ttacccgtga
    11461 cattagatga aaagagacaa aaagaattgc agcaactaaa gcagaagtac ggaaaaagtg
    11521 aatctaagat tatgtgtatt gcgttagatc tattgatcgc gcaagaaaaa gcaggatttg
    11581 atataccagc actaaaaaag tgacgtcact tttcatttga agaaacaaaa gtgatagcac
    11641 ttaattgttc ctactattta gaatattttc tatgtccttt ttattccatt ttgtatcaat
    11701 aactatgaaa tctttaaagt atccagatca atttttttct tacctgattc taaagatttt
    11761 gttttcttaa acatattatg atttcctttc gactattttc atataaatgt taacatagtt
    11821 tatggattca tggaatgtta atctaattta atagaaaagg ataattaagt atatacgttt
    11881 tttcttatgt atgttatact atgtatatac agaaagaggt gtctactatg gaaatgttac
    11941 ctataaaaaa atggggaaat agtaatggcc ttagattgcc aaagtatatt atggaatatc
    12001 ttggaattca tacagaagac aaagtgaaga taatacaaga agaagtaaac ggtcagaagc
    12061 ggctaattat cgaagcggct aatatagaaa atgaattaac aattgaacag ttatttgaaa
    12121 attacactga tgaaagaaat catgtgacga ttcaaaattt aggtgaagca gtaggtaatg
    12181 aaaaatggtg agaaaaccta gacaaggcga tattctatta ttgaatacag cacctcgatc
    12241 tggacacgaa cagacaggta aaagacctta tattgtttta agtcatgata ttattgcgga
    12301 ttatagtaac gttgttacag ttgctccaat ttctagtaca actagaaact atccgctata
    12361 tgtaaatata aactcagaat atgaaatgaa gacaacagga aaagtattat tagatcaact
    12421 aacgacaatt gattatgaag ccagagagtg tatttttttg gaaaaagcgc atgatagttt
    12481 agttgaggag ttattgatga aagttagaac agtttttcaa aaagtaagca aataaaatag
    12541 aaacagcagc atgatcaact attcgtgatt gaccatgctg tcttttttta ttctatatac
    12601 ggtttgtctc gtaacattgt agtcttttgc aatcttagcg atcgcaacac ctttttttag
    12661 atcctcaacg atgtttttat aaacaagacg acgttgggga tcttttgcat tggcactgta
    12721 tagcttagga cgtcctttat aaacaccgtt cgcttttgca atcttaatgc cttgtgcctg
    12781 acgtcgttta gattcggtac gttcttgttc agcgatcatg gccaaaattt gaatgatcaa
    12841 atctttaatg aatttatcca ggagaggatt gccaattgct tcggccatga tcggtagact
    12901 tgtgatgatc agctgcacat ttttcttctt caagtaattg actgaagcga tgatctcgtc
    12961 gtaatttctt ccaagtcgat caatagcttc cacaataaaa atatcttgat ctcggacgaa
    13021 atccagtgct tcttgaaaaa caggtcgatg agtaatcgtt gcgccagatt gtttctcaat
    13081 gaaaattctc tctgcaccga attttttcat ttcttcaatc tgccgttgtt cattttgatc
    13141 gatggatgag acacgtatgt atgcaactct caaaattttt acctactttc tgcaactatt
    13201 taaaaaacac cctaatcata cacgagaaaa ccagattttt caatgtcgcg gtcgtgtcta
    13261 gttagggtat accttatata gacaaaaact aatgatggag gaaatagtat gtgtcacttt
    13321 tctttttaaa tggcaatatt ttttgtaaat aaatgtcaat caagaaaatt taaacgatta
    13381 tgacattaaa aatatatttt atgaattttc tagtatataa cttgatttat ctgttaagat
    13441 ttattaagaa aacgttttct tatttttgat ttcgaggtga tagacaatga aaaataagtt
    13501 tattttatct ttaggtattt taactattgg aattagtgta actggaacta caattcctac
    13561 atttgctgat agtacaaatg aaccaactac tgtagtagat aataaccaag aattaactcc
    13621 tttagatagg aacggaatag ccattggtaa cccaactaac gacttaactg ttactgaaaa
    13681 ttatttaata gtttctccat tacttgctcg agcagcttct aaaacgatac gagtgacagg
    13741 aacgatgatt tttgataaag ttggttggcc ttctagacct cctcaatcac ggaattggaa
    13801 agaaaaaaga aatggttatt ggtactatgg aaaattgtat ttacaaagtt ataaatcagc
    13861 tggaaacaat tggattgcga cttattcagg aaccttaact agaaagtagg gattttttat
    13921 gccagaattt gtgaacacac caaattttta tcaagatagc gatattctaa gtaaaattaa
    13981 tttaccgaaa gaagaatcag ctttacaagt tcagcgaact ttacaggaga cacaaaaaat
    14041 tcaaaaatca atttctaatc tagaagattc tgaagaaaaa agaaaaaaaa gagaccaaaa
    14101 aacatatcaa aaagaaaaat aatgatttta aaaaaagagt gtctagtcga cattcttttt
    14161 ttctaattga aagtgttcat aaaatcaccc atttctggac actttctttt tttgctttat
    14221 ttttcaaaaa aacaattcat ttcatgttca taaacccata acaatatcta tgttcagtta
    14281 aactatatgg ataaagttat gttacaataa aattaatgaa ggagtgattt ttttgaaaat
    14341 aggatacgcc cgggtatcta ctggtttaca aaatttggat ttacaagaag acagcctaaa
    14401 taaatttggt tgtgaaaaaa tttttactga tcatatgagt ggggcaaaaa gtaatcgacc
    14461 aggattagaa atggccattg attttgttcg ctctggcgat acacttgtcg tttggcgctt
    14521 agatcgttta ggtagaaata tggaagattt gatttcaatc gtcaatcgac tgaatgagcg
    14581 tggtgtgagt tttcatagta ttcaagaaaa tattacgatg gacaaatcaa gttctacagg
    14641 acagctcatg tttcatttgt ttgcggcatt tgcagaattt gagcgtaatt tgatcctgga
    14701 acgatccgca gcaggacgag cagctgctcg tgcaagagga cggtttggtg gtcgtcctga
    14761 aaaattgtct gaacaagatt tggaattact gaagacttta gtggatagcg gtacacctat
    14821 taagactatt gcggaacggt ggaacgtctc aagaaccacc atttatcgtt atttggcaaa
    14881 aatggaggag aaaaatggaa agacaaattc tcattagttt ttgtcattta atgctgaaaa
    14941 tttttgccat ttatctagaa aagtgacaat agtatgagaa ttttttgtaa gtgtctactg
    15001 ataacttatt ctcaaatgtt gtaaggattt tattcatttg ttaatattaa agaacggaac
    15061 tccaaaaaag tccgtactct aatttgcagt ctctcactct tttagagtga gagtttttat
    15121 tagatt
//
LOCUS       DADVXE010000068        14010 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.069, whole genome shotgun sequence.
ACCESSION   DADVXE010000068 DADVXE010000000
VERSION     DADVXE010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14010
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.069"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            170..2335
                     /gene="acm"
                     /locus_tag="KB913_002262"
     CDS             170..2335
                     /gene="acm"
                     /locus_tag="KB913_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBB6820598.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2607..3092)
                     /locus_tag="KB913_002263"
     CDS             complement(2607..3092)
                     /locus_tag="KB913_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBB6820599.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3182..3527
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3572..4213
                     /locus_tag="KB913_002264"
     CDS             3572..4213
                     /locus_tag="KB913_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6820600.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4232..4867
                     /locus_tag="KB913_002265"
     CDS             4232..4867
                     /locus_tag="KB913_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6820601.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4885..5700
                     /locus_tag="KB913_002266"
     CDS             4885..5700
                     /locus_tag="KB913_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6820602.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            6019..7455
                     /locus_tag="KB913_002267"
     CDS             6019..7455
                     /locus_tag="KB913_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6820603.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKSSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7644..10076
                     /locus_tag="KB913_002268"
     CDS             7644..10076
                     /locus_tag="KB913_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBB6820604.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPI
                     DSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPT
                     VDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVG
                     VKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNH
                     PDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEV
                     KLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNI
                     SGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGI
                     HMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLP
                     MGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELF
                     EEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQE
                     ETSETLPDDNDM"
     gene            10306..11373
                     /gene="rlmN"
                     /locus_tag="KB913_002269"
     CDS             10306..11373
                     /gene="rlmN"
                     /locus_tag="KB913_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBB6820605.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11566..12669)
                     /locus_tag="KB913_002270"
     CDS             complement(11566..12669)
                     /locus_tag="KB913_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6820606.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13221..13769
                     /gene="aac(6')"
                     /locus_tag="KB913_002271"
     CDS             13221..13769
                     /gene="aac(6')"
                     /locus_tag="KB913_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBB6820607.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         4795 a         2317 c         2963 g         3935 t
ORIGIN      
        1 cttgtaaaaa cagttttttg gcatatttat tttttataaa tatttgtaaa ataactatca
       61 attttttagt taaaagattg gaaatgagtg ggggaggaat tgaagaaagg atttttgaga
      121 gatgatatag taggttttat ttttagttaa aataggggag atagaaaaaa tgaaaaagtg
      181 tagaaatatt attttatcaa tgttatttat tattactaat ataacatcac tgattcctgt
      241 tcatgtctat gcggatgcag gcagagatat cagcagtaat gtcacttcgt tgaccgtgga
      301 cccaacgaat attacagatg gaggaaacat aaaagtaaaa ttctcgtttg acgaaaaaaa
      361 acaaaatatc caaccaggtg attatctttg gatcaattgg ccaagtgaag gaaatattcg
      421 cggtgaagga ttccaaaaag aaatcccatt aatgattgaa aataaaaatg ttggaacttt
      481 aacggtcaga aaagattctg cgcaggttgt gtttaatgaa aatattaaaa acctagactc
      541 agtagaaggt tgggggcaat ttgagataca ggccagaaac gtaaccgata ccggtgaaga
      601 aaatacggga ccattcaccg tgacgagcgg tgataaaaca gctactgtaa atgtgacaaa
      661 gccagcttct ggttcttctt ctagcgtttt ttattataaa acaggagaca tgctacctga
      721 agatactaag cacattcgat ggtttttgaa tattaacaat aacggcactt atgttgaaca
      781 accagttaaa atcagtgatg aaatccaaag tggacaaaga ttagatccaa gtacgtttga
      841 aattaatcaa atacacttag gtgaacagaa ggtttataga ggagaagagg gaatccaaca
      901 atttttacaa gatttcccca gcgctacatt taatttttca gtaactgata attacattga
      961 aataactata ccaaaaaact ttgtcaatct taggaaaata atggtgagtt ataagacgat
     1021 catagaaaac ccagaacaaa taaattttga gaatcattcg gaagcttggt ttaaagaatt
     1081 taataaacct gctgttgatg gagaaagttt caatcataca gttaaaaata tttcagcttc
     1141 tggtggagtc aacggtacag ttagaggcga attgaagatt ttcaaatata tcaatgacac
     1201 agagattggt atcccaaatg tgactttcga attaagacga gcagatgaac agcctattca
     1261 aggacagtct agtatcctgt tgacttcgaa tgaacaggga gaagctagta tcaaaggcct
     1321 gcaagtagga gactatgttg taaaagaaaa agaagcaccc aattggattg attttgatcc
     1381 actaagttca aatgaactca aattctccat aaacgaaaat gatacagagg gagtcagttt
     1441 acctatttat aacaagaaaa aggttacgaa catcacagca actaaaattt ggaacggtgg
     1501 aaccactcca agaccgagta tttattttaa attattcaga gcaagtacaa acaattggga
     1561 accagttcct gatgcagaaa caaaacgatt agacaatgga ataacttcag tgacttggga
     1621 agatatccaa cagtatgatg atagtggaaa cgaatatacg tttaaagtgc aagaagtaga
     1681 tcaaaacgga aatgattatg tcccttcagg ttatcaaaaa attgaaaacg ggctagtcgt
     1741 tacaaatgag aataaagaag tcatttcagt ctcaggacaa aaaacatggg aagacaatga
     1801 gaaccaagac ggcaaacgac cgacgacgat cacagtaaat ctattagccg acggtcaacc
     1861 gatccaacac aaagaagtaa gtgaaaaaga tgattggcgc tatcgtttca caaatctgcc
     1921 aaaatacaga gacgggcaag aaatcatcta tactgtaacg gaagacaacg tgcccgaata
     1981 cagtacgacg attgacgggt ataacatcaa aaacagttat acaccggaaa aaacaaatat
     2041 atctatacca ggtagccata taacaccgtg gaaaaatttt ccagagaaga cagagagaga
     2101 gaaaattaga aatctattct ctcaaaaatt gcaaatattt gctcatacag gagaatccag
     2161 cgaacaaaga agcaattata ttagtaagag agctgtacct aaacagataa caaataaatc
     2221 aaaaagcatt cttcctaaaa caagtagtaa aaaatctagt tttgctgtaa tcattggttt
     2281 attgatagta actatctgtg ctgggatatt cttacaaaaa tataaaaaag tttagttaga
     2341 atataatatt ttttgttaaa tatgactgaa atcaaaagaa taaaattccg atttataatc
     2401 gaaaaaagaa gcatttttat atatgcttct tttttcgtag aatcaataaa tatggatttg
     2461 gctaactatg gaagaatact cgtattagtt ttcagcgttc atactagttg ttacattgtt
     2521 tgattggcca aaagaatttc tgatatattt tgtgctaaat aaagaaaaag acgcttgaat
     2581 tgggaaataa gaaaactact ctatcattac aaattttcat aaactggcag atgttctaag
     2641 taaacaagta tcttttcaaa gtcggaaaaa tccataatca acgtagtggt attgatattt
     2701 ggatgaaagc ctacggtatc ttgacgatca atagcagcat cgatcacgac ttggattttt
     2761 ttctctttgt cgtgcatcaa tgctaatgga gtcactgtac ctgctggaac gcctaggagg
     2821 tcaggaagct gttcttcaga aacaaaagat aagcgctttt cttttaattg ttcagctagt
     2881 tgttttaaat cggcgtgctt ttcatcaggc aagatgacaa gatagatttg ttttcctttt
     2941 cttgatttca ataatagatt ttttacttgc ggaccaggta gggaaaaagg gacatttttg
     3001 actgacgtaa tcgcaggatg atcgactttt tgaaaagaga tacccagttt ttttagtagt
     3061 tcataagctt cttgttcggt tgcacgactc atcgcgcatc accctccttt ttttattagt
     3121 gtatcataaa aaagagttga caaatgaaaa ataatcatgt aaattacacg taaagttaaa
     3181 acaaatgaca tcgaaaagaa gagtagccgt taggtgtttt tagagagtct ctggttggtg
     3241 gaaagaggca gcagttaacc gtgaaacaca tcttggagtc gattttctga agcgtatagt
     3301 aggaaaatcc ggggagcccg ttacagctgc ggtcgttgct agatgaccag ataaggctgg
     3361 cttttccgtg aggagtcggt aaaaaaaggt ggaaccacgt gattaacgtc ctttgatctt
     3421 cggatcaaag gactttttgt tttcatctga acggcaacga ctgtgtgagg ttttttctgc
     3481 aaggaaaaaa taaacagagg tggaaccacg tataatacgt cctcttggca tttgccaaga
     3541 ggattttttt attttaaagg aggaaaagaa gatggagtat ttgattgaag ttatgccgca
     3601 attattagta ggagcactca caacattgaa attattttta tttaccttga ttggctcatt
     3661 accattaggg attgttttag cattaggatt gtctttgcat tttaagccgc tacgctactt
     3721 gcttcaaaca tatgtatggg ttatgcgggg aacaccgctg ttgttgcaac tgatttttat
     3781 tttttatggg ttgccgacga ttgggatcgt ttttgatcgt ttcgaagcag cactcattgc
     3841 ctttatctta aactatgcag cttattttgc agagatcttt cgtggaggga tacaatcgat
     3901 tcctcaaggt caatatgaag cagcgcaagt tttgcaatta agtccctttc aaacggtgac
     3961 gaaaatcgtc atcccacaag tgacaaagat tgttttacct tctgtaggga atgaagttat
     4021 caacttggtc aaagattctt ccttgatcta tatattaggt ttaggtgacg taatgcgtgc
     4081 tgggaaaatc gcgatggaac gcgacgcgac tttactgcct ttgctaggcg tggcaatcat
     4141 ctatcttaca ttgactggta ttctaacaat cgtaatgaaa caagttgaag gaaaattaaa
     4201 ttattaccgc taactgatag gaggaagaaa tatgattgaa ttgaagaaag tgaacaaagc
     4261 atttggtgaa aaaaaaataa tcaaagattt gaatctaatc attccagatg ggaaaacatt
     4321 agctatcgta ggtccttccg gtggcggtaa aaccacgctt ttacgtatct tggctggctt
     4381 agaaagttct gacagcggag aattttattt agacggtgta ccgttcaacc cattcgagct
     4441 taaaatgaaa gaacaagttg taggagtcgt attccaagac ttccagctat ttccacatct
     4501 gaatattttt gaaaacatta ccttagcacc aaaaatggta ttgaaacaga caaaagaaga
     4561 atacaccaaa aaagcagaag aattagcggc ttcattaggg attagtgatt tattgaatat
     4621 ctatccttat cagctttctg gcggacaaaa acagcgggta gcgattgcca gagcattggc
     4681 tatgaatcca cgggtattgg cttatgatga accaacaagt gctttagatc ctgaattacg
     4741 ccagcaagtc gagcgtttga tcctatcatt gaaagaagat ggggtaaccc aaattattgt
     4801 cacccatgat ttagtatttg cagaaaatgt cggtgatcaa ttactaaaag tttccccaat
     4861 tcattaagaa aggagaagat agagatgaaa aaaaccagtt ttctattcgc tttgatcgca
     4921 ggtcttcttc tttttgcagg ctgttcgaac aaaaaaactt cagcagataa ttgggcgact
     4981 atcaacgaag agaaaaaaat cgttataggt ttagacgata catttgttcc tatgggattt
     5041 agagataaag acgggaagct cacaggattt gatattgatt tagccaaagc agtctttgaa
     5101 caatatggga ttacggtaga ctttcagccc attgactggt caatgaagga atttgaactg
     5161 aacaatggaa cgatcgattt gatatggaac ggctattcca aaacgccggc aagagaaaag
     5221 aaagtgcaat ttacaaaacc ttatatggaa aacgatcaag tgctgatcac acctaaagaa
     5281 tcaggaatca caaactttgg acaaatgaat aataagagat taggtgcgca aaatgggtca
     5341 tctggttatg atgtatttac gaaacaacca gaagtattaa aagagatagt caaaaaccaa
     5401 gatgctgttt tgtatgatag ttttaatgaa gcattgatcg atctgaaaag cagacgggtc
     5461 gatggtctgc tgatggataa agtatacgca gactattatt tgaaacaaag aaacgaacta
     5521 gaagacttca acataacaaa aggttcttat gagagtgagg attttgcagt tggtgcacgc
     5581 aagtcagata gtacattagt gaaaaaaatc aatgaagccc tagatcaact agagaaaaca
     5641 ggtgaattcc aaaaaatatc cgataaatgg tttggcgaag atgttacgcc gagaaattaa
     5701 caaatagggg actgtgacaa aagacgtgtc acagtccctt tttccgaata aacagtgttc
     5761 tcctgccaac tccttgtgac tcggagctga atggcaggct cacaacctct tggtaaacgg
     5821 tgttcaaaag ccagtttttc ggtattaagc caaatttatg caaaaatgta gaaagccatt
     5881 ttcacaaaat ttttcttact actcgaaact aagcgacttt ttcacaacct cctttacata
     5941 attttatttt gttgtggaag gggtttcgtg ttattctaaa agaggaacga ttgaaggtta
     6001 taggaaagga agagatgaat ggaacacaaa gaacttacct catttccaaa agattttctg
     6061 tggggctctg cttctgcagc gtatcaagta gaaggagctt ggcaagaaga tgggaaagga
     6121 gaatcagtct gggatcgatt tgtacggata cctggaaaga catttaaagg aacgaacggt
     6181 gatttggcag tagaccacta tcatcgttat aaagaagata ttgctttaat gaaagaacaa
     6241 ggtctgaaag cttaccgctt ctctgtagct tggacacgga tttttcctaa tggacgagga
     6301 gaagtcaatc aagctgggct cgctttttat gagagattga tcgacgaatt gattgaaaac
     6361 gatattgaac ctatgttgac tttatatcat tgggatcttc cacaagcatt gcaagatgaa
     6421 tataatggtt gggaatcacg tcagatcatt gaagatttca ctcattatgc agaaacatta
     6481 tttgaggcat tccgcgggaa agtccattac tggattagtt tgaatgaaca aaatatcttc
     6541 acttcattag gttatttgtt agcagcacat ccgccaggtg tgacagaccc gaaacgaatg
     6601 tatgaagtta accatattgc taatttagca aatgcatctg tcatcaataa atttcacgag
     6661 ttagaaatgc ctggaaaaat cggaccaagc tttgcgtata cgccaaatta tccaattgac
     6721 agtaatcctg aaaatgttct ggctgctgaa aatgcagaag acctgatggc caattattgg
     6781 atggatgtct atatgtgggg aaaatatccg attgctgcca tgaggttctt agaagaaaaa
     6841 ggatgggcac caacgattga agctggcgat gcagaattgc tagaatctgc taaaccagat
     6901 tttcttggga tcaattacta tcaaacggcg acgaatgcat tcaatccatt aaacggagtt
     6961 ggtgctggaa aaatgaatac gacaggaaaa aaaagttcat cagaagaaac tggagttcct
     7021 ggaatgtata aaaaagttga gaatccattt gtcgaacgaa caaattggga ctgggagatt
     7081 gacccagaag gattaaggat cggactgcgt cgtatcacaa gccgttaccg catgccggta
     7141 ctgattacgg aaaatggctt aggagagtat gacaagttga cagaagataa acaaatccat
     7201 gacgactatc gaatcaatta cttacaaagc cacgtcaaag ccatcaaaga agcaatttcg
     7261 gatggagcag aagtcctagg ctattgcacc tggtcttata cagatttgct tagctggctg
     7321 aacggttatc aaaagcgata tggatttgta tatgttgatc aagacgaaac acaagaagga
     7381 tctttggaac gatataagaa agacagttat tactggtacc aaaaactgat tgaagaaaat
     7441 ggagagaacc tttagttcac atacttaaaa caagaaggta cggctggata tggccgtgcc
     7501 ttttcttgat aaaatcattt agaaattaag aaaaactgta aaataagctg aaaaatgaaa
     7561 gaaagcgtca gttctttcaa acaaaacttt agttccctta cttttttttg tataatgaaa
     7621 cttgatgaaa tgagggataa taaatggcac aaaagaaacg gcctactaaa aaaaggaaaa
     7681 agacgaaaaa aacgaaaaag caaaaacagc agcaggaaca aatgctgacg attggtgttg
     7741 ggtttgcctt gattttattt gctgtcttcg gctttttaaa attaggtttt ttaggaatat
     7801 tgattgcaaa cggctttcgg atcattgcag gaaatactta ccaaatcctc tgtcttttat
     7861 tagccgtatt aggattttgg attgtcatta agaatacaga gttttcaatt ggtaaaaacc
     7921 gacgctggtt tggcggcata ctcttttatt tcggtatctt attattgtta catgcccatt
     7981 tatttggcaa actccatact ggggaaccaa atatcatggg gacgacatgg gatttgttag
     8041 ccagtgatat aaaacaaagt caagtagaca ataacgttgg tggtgggatg attggagcaa
     8101 tcctttatca ttttacttac ttcttgattg cacagcctgg aagttattta gcagcagtgc
     8161 tattactggc aggaggagca ttcctgttca gtaatctgga aggctatcag ctgttaaatg
     8221 gtatccaatc aattggagaa cgagtacagg aattattgga aggtgatcct gccaagcaag
     8281 ctcgaaagca agcggcaaag gaagagagaa tgaaacagcg cgcagaagcg aaagaagcaa
     8341 ggcgcttagc tgcaaaagaa gctgcagaat atgagaagaa aaaagcggtg agccagcaaa
     8401 gggaaaatac tgctgatgaa tggcaggaac cagaaaatac agagccggag cagctaagtt
     8461 ttgttccaat cgacagtttt caagaaaata tccatcctgc gaatctagag aaaccagtac
     8521 cagatacacc aaaacagacc aatacagcag aaggtttttc agatgagttg ccagaggatg
     8581 acggtacctc attagaattt gagattgaag cagaacagga aaatcaagac tatgaattac
     8641 cgacagttga tttgcttgat tctataccaa ctgtggatca aagtgatgag tataaaaaaa
     8701 ttgaaaaaaa tatcggcgta ttagaacaaa ctttccaaag tttcggtgtc gatgccaagg
     8761 tcgtcaaagc cagcttagga ccatccgtca caaaattcga agtccagccg gctgtagggg
     8821 taaaagtaag taaaattgtg aacttaacag atgatatcgc gcttgcttta gcggcgaaag
     8881 atgtccggat ggaagcaccg attccaggta aatcactgat tggtattgaa gtaccaaatg
     8941 gaaagatcag tatggtttcc tttagagaaa tcatcgaagc acaaccaaac cacccagata
     9001 aattactaga agtaccttta ggacgtgatg tttctggacg ggtacaaacg gctgatcttt
     9061 cgaagatgcc tcacttactc gtggctggtt cgactggtag tgggaagtca gtagcaatta
     9121 atgggattat cacaagtata ttaatgcgtg ctaagcccca tgaagtaaaa ctgatgatga
     9181 tcgatccgaa aatggttgaa ttgaatatgt acaacggcat acctcatctg ttgacgccgg
     9241 tcgtgacgaa ccctagaaaa gcagcgcaag ccttacaaaa agtagtacaa gaaatggaag
     9301 aacgatatga aaaattcgcg gcaaccggag taagaaatat ttctggttac aatgaatttg
     9361 ttcaacagaa aaacttggaa aacggaacga aacatccaac cttaccattc atcgtagtga
     9421 tcgtagatga attagctgat ttgatgatgg tagccagcaa tgaagttgaa gatgcgatta
     9481 ttcgtttagc gcaaatggct cgggcagcgg ggattcatat gatcctagct actcaacgtc
     9541 caagtgtgga tgttatcaca ggaatcatca aagcaaatgt accttccaga atggcatttg
     9601 cggtatcaag cggtacagat tctcggacga tcattgattc taatggggca gaaaagctct
     9661 tagggcgagg agatatgcta ttcttgccaa tgggtgagaa taaaccgatc cgtgtgcaag
     9721 gagcattcat ttctgaccac gaagtagaac gggtcgttca atttgttaca gatcagcaag
     9781 aagctcatta tgaagagaaa atgatgccga cagatgaagt tgaaacgaca ggtgctccag
     9841 aacagccaca agatgagctg tttgaagaag caaaagcact tgtcgttgaa atgcaaacgg
     9901 caagtatttc ccttctccaa agaagatttc ggatcggtta caaccgagca gcacgtttag
     9961 tagatgaact ggaagctcat ggagttgttg gcccgtcaga aggaagcaag cctcggaaag
    10021 tattcattga gcaggaagaa acatcagaaa cgttgccgga cgataatgac atgtaaaact
    10081 tgtgtgatga agggttgaaa aacgaataac caataaaaag acaaggcatg atgataccaa
    10141 aagaaaaaat ggtttttttc catcttttct aatacggtat gatgtcttgt ctttttagtt
    10201 tttgtgagat taaagttcta ttcgatttat ttgtgaagta ttgcattaag gaaatgaatc
    10261 atgtatagta tgtagcgaaa ctttgagaaa aagagggaaa atactttgga aaaacagtcc
    10321 atttatggct tgacgaatga agaattaatc aattggttta tagaaaacgg cgagaaaaaa
    10381 ttccgagctg cccaagtttg ggaatggttg tatcaaaaac gtgtaagtaa tttcacagaa
    10441 atgacgaatc tatcgaaaca attgatcgaa aaattatcgg agcattttat catcaatcct
    10501 ctaaaacaga tggtcgtcca agaagcttcg gatggtacag taaaatattt gtttgaactc
    10561 cctgataaaa acatgattga gactgtactg atgagacaag aatatggctt gtcagtttgt
    10621 gtgacgacac aagtaggatg taatatcggc tgtacgtttt gtgcaagcgg gctgctcaaa
    10681 aagaaccgtg atctgactgc tggagaaatt gttgcacaga tcatgatggt ccaacattat
    10741 tttgatgagc gcaatcttgg cgaacgcgtt tcacatgtcg ttgtaatggg gatcggtgag
    10801 ccatttgata attacgacaa tgtaatggac tttttgcata tcatcaatga tgccaaagga
    10861 ttggcaattg gtgctcggca cattacagtt tccactagtg gattagcaca caaaatcaag
    10921 gaattcgcta ataacggctt gcaagtcaat ctggctattt ccttgcacgc gccgaataat
    10981 gaggtgcgaa catcgatcat gcggatcaac cgaagtttcc caattgagaa attgatggaa
    11041 gctgtggatg agtatttaga gaaaacaaac cgtcgaatca cgtttgaata tatcatgttg
    11101 aatcaagtaa atgatagacc agagcatgcg caacaattag cagatctatt aaaagataag
    11161 aaaaaattag catatgtcaa cttgattcca tataatccag tcagtgaaca tgatcaatat
    11221 tctcgcagtc caaaagctga tgtattgaga ttttatgatg tattgaagaa aaacggcgta
    11281 aactgtgtga tacgtaaaga acatggtaca gatattgatg cagcttgcgg acaattgcga
    11341 agcaagcaaa tgaaaaaaac agttgccaaa taatcgtatc ctactcgttt tttcaattac
    11401 cataaaagga gcagttttct taattaagga actgttcaac ttaaataaga gaaaagattc
    11461 tatagcgaaa gctataaagc tttttttgac aagaaaaacc ctcatcaagc aaagaaatgt
    11521 cctcaatttg atgacagcct gcttgatggg ggttttagca attatttaac tgattttctt
    11581 atatccttgc tggctttctt gtgtagcatg ataagtttct acgtcaagaa tggcctgttt
    11641 aaatttttct cgggtgattt cataaggcac atgtttaata tcatttgttg ccatggcttt
    11701 atctaagatt gcttctaaat cggtcgtgac attgagattc atgtcggtta acgatactgg
    11761 aagttggttc tttttcataa acacatagat tttatcaaac aaatcgaact gctgatccat
    11821 catcaataag gtcagtacac cataactgac agatgctccg tgaaggtatc cctccatttt
    11881 ttctagaaca gtcgtaccgt aatagaatga gtgtgccata gcagaattat agttattgtt
    11941 aactaaaaca gaaaccaatc cggtagtaac aatgatatcc gaaacgactt gttcaattgc
    12001 atatgaggga cgatcgtcgg cactatcttt caatgcttgc gtaccataag tcaagagacg
    12061 atcaatgcac atttttccga tttggattcc taatctatcc gtgtagccta gatcatcgcc
    12121 acgagcagaa aaagtagatt cgacttcttt ggataaagca tcgccaatac ctgcccataa
    12181 gtatttatca ggtgcttcgg caataattgc tgtatcaatg aaggtgtgta caggtggttt
    12241 tgaaggaaag aagagtccgt ccattacgcc ttcttcgtta tagatgacac ataccgcagt
    12301 gacgggcgaa cagttcgaac caatagtggg aaaggtgaag actggtttag ctagtttttc
    12361 accaatgact tttacagtat cgcaagcacg gccaccaccg actgcaaaca ggacgtctgc
    12421 tttttggaca ctttcatgct ggatcaactg ttcaatattt ccataagttg aattaccccc
    12481 gtaccagaga ctggcgacaa cctctatttc ctgtgtcaaa gctactttta ttttgttttc
    12541 tgcctttgaa agtgcagtct tccctccaat cagcactact tttgtcccat attctttgac
    12601 gattccattt gctttttcat acgcatctgt tccaatggta taatttggta agaaaacact
    12661 ttgactcata ttcatttcct tctttcttcg ttgaaacggg ttaaaatttt aaagagtgat
    12721 cgatctgact gcggctgtag atggagtaga ggtgaaccta agacaggata agtgatgaat
    12781 aaggtggcat gaacaccttg aaatcatcaa taagtatcct aaaaacgaac aagtacaaaa
    12841 acattgaaaa cgacaataat gaatttttgt tcctcttagt atttctaccg attccctttg
    12901 cttttttgta attatctaaa aattctaaaa attaagatta ttatatgaaa acaggtttta
    12961 tttgtcaatt cataattggt tttttttaaa gcaaaagata atctatatca tgatgaacaa
    13021 acagagtttt ttcctccaat tgatggcttt cctgatcttt cctattttga ataaagtgtt
    13081 tctgtataat tttttatttt ataagtaaga taaataatga aagaatagag atactgattg
    13141 gtagctaaag atttttgagc gagaacattt cgttttttca aaaggactgt tagaataagc
    13201 aagaacaagg gggaagacgt atgataatca gtgaatttga ccgtaataat ccagtattga
    13261 aagatcagct ttctgattta ctgagactga cttggccgga agaatatgga gacagctcgg
    13321 cagaagaagt agaagaaatg atgaatccag aacgaatcgc ggtagcagcg gtagaccaag
    13381 atgagttagt aggatttatt ggtgcaatcc ctcaatacgg tatcacaggt tgggaattgc
    13441 atccattagt tgtagaaagc tcccgacgaa agaaccaaat aggtactcga ttagtcaatt
    13501 acttagaaaa agaagtagct tccagaggag gaatcacgat ttatttaggt acggatgatt
    13561 tagaccatgg aacaacgtta agtcaaacgg acctgtatga gcatacattt gataaagtgg
    13621 cttccatcca gaaccttcgt gaacatccgt atgaattcta tgaaaaatta ggttataaaa
    13681 tcgtaggtgt cttaccaaat gcaaatggct gggacaaacc ggatatttgg atggcaaaaa
    13741 cgattattcc tcgaccaaat tctcaataat aaaaagaggt tgtgacagaa gtaatcagct
    13801 tcaagaaata agaaggaatt tacgaaaatt acttcttgaa tttttgtgaa attccaactt
    13861 atttccgaag aagctacttt tggaacaccg tgtaccagag gttgtgaaaa agtcgcttag
    13921 tttcgagtag taagaaaaat tttgtgaaaa tggctttcta catttttgca taaatttggc
    13981 ttaataccga gaaactggct tttgaacacc
//
LOCUS       DADVXE010000069        13891 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.070, whole genome shotgun sequence.
ACCESSION   DADVXE010000069 DADVXE010000000
VERSION     DADVXE010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13891
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.070"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..202
                     /locus_tag="KB913_002272"
     CDS             <1..202
                     /locus_tag="KB913_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6820608.1"
                     /translation="NVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIGKVLG
                     ITRQGATNLKHRLYKKIQKMLV"
     gene            296..487
                     /locus_tag="KB913_002273"
     CDS             296..487
                     /locus_tag="KB913_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820609.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            1001..1333
                     /locus_tag="KB913_002274"
     CDS             1001..1333
                     /locus_tag="KB913_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6820610.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            1629..1784
                     /locus_tag="KB913_002275"
     CDS             1629..1784
                     /locus_tag="KB913_002275"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBB6820611.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            2060..3400
                     /locus_tag="KB913_002276"
                     /pseudo
     CDS             2060..3400
                     /locus_tag="KB913_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(3641..5257)
                     /locus_tag="KB913_002277"
     CDS             complement(3641..5257)
                     /locus_tag="KB913_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBB6820612.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKKIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            5375..5593
                     /locus_tag="KB913_002278"
     CDS             5375..5593
                     /locus_tag="KB913_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820613.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            5788..6249
                     /locus_tag="KB913_002279"
     CDS             5788..6249
                     /locus_tag="KB913_002279"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6820614.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(6442..6681)
                     /locus_tag="KB913_002280"
     CDS             complement(6442..6681)
                     /locus_tag="KB913_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820615.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(6705..8228)
                     /locus_tag="KB913_002281"
     CDS             complement(6705..8228)
                     /locus_tag="KB913_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBB6820616.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(8246..8368)
                     /locus_tag="KB913_002282"
     CDS             complement(8246..8368)
                     /locus_tag="KB913_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBB6820617.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(8398..9381)
                     /locus_tag="KB913_002283"
     CDS             complement(8398..9381)
                     /locus_tag="KB913_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBB6820618.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(9405..9554)
                     /gene="rpmG"
                     /locus_tag="KB913_002284"
     CDS             complement(9405..9554)
                     /gene="rpmG"
                     /locus_tag="KB913_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6820619.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(9575..9952)
                     /locus_tag="KB913_002285"
     CDS             complement(9575..9952)
                     /locus_tag="KB913_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820620.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(9984..10163)
                     /gene="rpmF"
                     /locus_tag="KB913_002286"
     CDS             complement(9984..10163)
                     /gene="rpmF"
                     /locus_tag="KB913_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBB6820621.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(10178..10447)
                     /gene="rpsN"
                     /locus_tag="KB913_002287"
     CDS             complement(10178..10447)
                     /gene="rpsN"
                     /locus_tag="KB913_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBB6820622.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(10970..12736)
                     /locus_tag="KB913_002288"
     CDS             complement(10970..12736)
                     /locus_tag="KB913_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820623.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(12696..>13891)
                     /locus_tag="KB913_002289"
     CDS             complement(12696..>13891)
                     /locus_tag="KB913_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820624.1"
                     /translation="ESLDVLSSETVEYIRGIQVIKIFGAKVTSFKALNKAINDYAKFA
                     YKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVDLLMLFFLSGIIFV
                     SFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNCDIAFENVSFSYKE
                     ECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQIKIGGKPLNHYSKD
                     TIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGCESILEKFPEREHT
                     LIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEYELQKAFQHLMKEK
                     TVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQLVTNYENANDWRLD
                     NEKFL"
BASE COUNT         4412 a         2671 c         2145 g         4663 t
ORIGIN      
        1 aaatgtgact ctccttgttg aagatataaa attagcaaaa atccttcctt tgttgaaaga
       61 acctgaacaa atttttctta tcgaaaaatt tatctttgat aaaactgata aagaaattgg
      121 aaaggttctg gggattacaa gacagggtgc gacaaattta aaacatcgac tttacaaaaa
      181 aattcaaaaa atgctggttt aatatctgca taataactaa ttttgtatgc ttctttgctc
      241 gttctcctcc ttcccaaaga aatagattat aagtccatgg gaagaaggta gatttatgaa
      301 ttctttaaaa gaagatttca ttttagcaaa ggctggaaat gaagaagctg ttgaggcaat
      361 tctcaaaaga tttagctctt tgattcataa gcaatcctgg agaactggaa aatatgatca
      421 agattgttat caagaatgta tgcttgcaat atatctagct atctcgaaat tcgaaattaa
      481 agaataactc aactaaggga gtctgtgaca taagtaaaaa gatagtttca aatttcgaac
      541 aataaatttg aaactatctt ctttataatt ataaagtatc gattttacag cgttctataa
      601 tgattcatag aatctaaaac gaatgatttt aattatcaac gttttttaat tcgtttttag
      661 cttaaaaata acttttgtca cagtctcact cctaaaatta ctttatttac gtatgaagtg
      721 ggcaggaggt cgaatccaga actgggctat ggtacttcaa cgaggacttc tcctctagaa
      781 ttgaaaagca tgcgatttac cttccgtaac gacggtagat ttattcaact atgtgtccaa
      841 tcaaaatttg tctgatttca aaaatagtca agagaatttt ggttgttaaa aactcttatc
      901 tatcaacttc cacagtttag ttgacaaacc ctgatactaa gttgggctat gatacacttt
      961 tcttgactat cagttacgtt accggaagga atgaactcta ttgagaaaaa catatgatcg
     1021 taaatttaaa ctaaagattt cacaggatat ccttgagaaa aaagtaacta ccaagaaaat
     1081 tgctgaagaa tacaatatct ctcgtccaac aatttcccga tgggtttcag aatatcgtcg
     1141 atacgggaaa aatgcttttg ctggacaagg aaaaagatta cctgataaag cagatttcta
     1201 cattcttgaa caggaaaata aacgactaaa agaggaagac gagtgttcta cgaacacaaa
     1261 gatcgatacg gatctccagg gatcactcaa aaactttacg atgaaggaat cgaaatcaat
     1321 aaacgtgttg tagctgttct tatgcgtgaa atgaatttat gcacaagagg atttcatcga
     1381 cgcaaatctt ctcatggtag agaaaaaaca atcaaagaaa tggtaaaaaa atgttgaatc
     1441 gataatttga acagaaccaa attgatgctg tttgggtgat ggatattact tacattccat
     1501 gtaatgacgg tcgcctctat ttgtccacct atattgactt agcaactcgt attctacgtt
     1561 actatatggt agattcacac atgaaaaaag agattgtcgt ccgtccatta caaatttatt
     1621 aaggagaatt gcctacggta attcattccg atagaggtag ccagcatcgg tcttttattt
     1681 atcaagagct gttgaacgac caccacatca cacattcagt gagccaaact gggactcctg
     1741 ttgacaatgc agtaattgaa gcgtttcatc gatcaatcaa atgagaatta atcgactcca
     1801 acaaatataa aagtaaaata gagatgaagg tgttaatcca agattattta gaagactact
     1861 acccaaacaa aagaatccat acaaaattta tgatgactcc ttgacaattt gaagcgaaga
     1921 aaataaggga tctataatat ctagtgttgg tgacgccttc tgttgccaat actttttctt
     1981 ttttctaata aacgcaaaca gacaccttaa aatcctttag aataaagtcg acgaaaacca
     2041 ttcaaaggag tgtttcaaga tgtcctattc agagtttacc aaagagttac tagatattct
     2101 agacctaaat cttatctttc atgaagatgc ctttcgcaaa gagcgaatca atgacgaaac
     2161 atgttttgtt tttgatggca cattgaccta tcaaccggag gaatgctttc atcgccacta
     2221 tcaaaatgaa caaacgatca ttaaataggg ctggaaaaaa gtatccatct tattgaatga
     2281 tgtcagtaac tacaagacca ttctgcggat taacaaacag cgcttcaaat gtaaacactg
     2341 tggaaagact tttttagcag aagattcagt tagtgatcgt cgctgctcca ttgctcgcag
     2401 agtcaaacaa gccattcttg agctattaag cgaacctctt tctatgtctt tgatcgcacg
     2461 tatgaagcac atttctccga ccactgtcat tcgaatactt cgcagccttc ggcctaaaac
     2521 catttctttg agccagctgt taccagaagt ggtgtgtttc gatgaattca aatcagtgaa
     2581 aaatgtctcg ggagccatga gctttgtcat gatggacggc aagacccatc aactgattga
     2641 tattgtggaa aatcggcaac tcaatccttt acgcgactat ttcttgcgct accctataaa
     2701 agtccgtgaa caagtgcgtc tagtggtttc agatttctat acaccctatc gcacattggt
     2761 gaaagagtgt tttccgaatg cccgaatcgt cgccgatcgc tttcatatta gccaacacat
     2821 tggtcgggct tttaccaacc accgaattca agtaatgaag acctttaaaa aaggggatcg
     2881 tcggtcgaag cacttaaaga aatactggaa actacttcaa aagaatgcgt gggaattgaa
     2941 aggtcagcat cgctactggc gtccgtcatt tcgagatcat ctgacagaag cagagatagt
     3001 cgatcggcta ttatcttatg atgattcctt aaagcgaggc tacgaagtct accaggattt
     3061 tctttccgtt atcagaagac aagatgttcc tgaattcgtc gcgctcctaa aagaagacta
     3121 caaggagttg ccagagcact accaaccagt gttcacgacc ttcaagaaat accaaacaga
     3181 aatcaaacga gcgttgcgcg ttccctattc caacggccct atagaatgtt tgaataacca
     3241 tatcaaagta ctaaaacgaa ttgcctatgg ctatagaaac tttcaaaact accgagaacg
     3301 aatcttttta tatcgaggaa aatattttaa gaaaactaag aatactaccc aactgactaa
     3361 agccagaaca acaacacggc tagacaagat agctgtctag ccgtgtgagt atctcgatta
     3421 ttctattgaa tttcttcacc aacactcatt gacgaagagc caaaataagt aatctaaccg
     3481 actgttaact aaaccattgc aggtcccgtt aaagatactt gtgcctgttg tcaccgcttc
     3541 tttttcttgt ccacaagcgc ttaacacact taataaagcc cctgctatta ttaataataa
     3601 tatctttttc ttattaaaaa cctcctcatc tatttccaga ttagtaaatg tagtaatctg
     3661 tgctttcttt tttctcaata ctaataacta acttatgggg taaacaaata ctcgtttgac
     3721 cgggttttga gatccatcca gttctaaccg cgatttgatc aggactatta tcttctttaa
     3781 ctcgaattct tccatcttta atctcaacaa tattatattg tcccttcgca ggatgataat
     3841 tcacgagttt atgattgatc ttatccaaat cgaagcgatc catttccttg ccatcaattc
     3901 gaacgatggc atatttgata gcatcttcag ttgtttcatt ctccttttct atagagaata
     3961 caaataaggg aataaaagag gtaataatca aaatgccaat aattatgaca tcgcctatct
     4021 tgacaccagc ttttcttaaa aatttcatta acgatatctg gctaaacata ttagactttt
     4081 tccatggaaa tggtgaaatt tttcggaaat tatctgcatt aagagaatca gttaaacaac
     4141 cctcaagttg ttccttaata cattgttgat ccatcttcat accaataaaa actagtttat
     4201 taatgcgttc accaaacaac ggatgccagg cttccttcaa ttcgggattt ttttgtataa
     4261 tcatttgaca ctcaatttta ggtaaactag ctacccaata atttaatgat tcaatacttt
     4321 tatagctacc cgatgtttca aagatcgtcg aaaaatcact atgttgggca aaccaaagaa
     4381 acccttttgc tcttgtaata ttgccaggaa aatttttatc cgtaagatgg gcaaattttt
     4441 gtgcgtcaag gagtaaccga tttcgataga taaaacttga gataccatat tcttctgttt
     4501 caggaatatg attttgatag ccaagctcta actctttgaa ccagcccact gaataggaag
     4561 tctcatctat attaaaaaga tttgtattta gaattttcga taagtctact tcacctttaa
     4621 ttgtcctaat tattttggca ttggactgta acttagcaat tagaccgtta attttgtaaa
     4681 tcgtcttggt tgacactaag tcactattat ttaaaagtaa tatgttacaa cactcgaatt
     4741 gatcaattaa caagccacga atatcctgtt cttcttcaac tacattacct tcagcttttc
     4801 tttcctgaat cttttcaccc gtttcgaaat tatcccaaaa acgttttaca tccactacta
     4861 taataatggc accaatctct aatcgttggg tcaaatcaat gtctaaaggg tttttagcta
     4921 atataattgc ttgaataatt ggaattggtt tgctgattcc tgaagcttca ataacaattt
     4981 gattcaagtc agaaaattgc actaattgat ctagttcaac aatcaaatct tcgcgtaatg
     5041 tacaacaaat gcatccattc ggcatcgaaa caagtttttc tccagttctt ttaaaacctt
     5101 tcttgtcgac taatacccca tcaacattta cttcccctat gtcatttaca atgacagcaa
     5161 ttttctttcc gtgatcaccg tacagaatat gatttagaag tatcgttttt cctgaaccaa
     5221 gatagccagt taagattgta ataggtattt ttttcatagg gaacctcttt ctataccttg
     5281 aatttacact ttaagtgcaa cacataaaaa tgagtcataa tcgatatcca actagtataa
     5341 gtttgtcgag aacactccta gaaggaaaat aattatgagc cagtatcgtc atcttactat
     5401 actcgaacga gaaagaatct ttctgcttca cgaagaagga ttttctatta gtataattgg
     5461 caacgacatt cagcatagcc cgtttactat tttacatgaa ctgagaagaa acaagaaaaa
     5521 aactattcac cttccaaagc ggaaaaaaat tatgcttatc gaagaaaaaa atgcggacgt
     5581 tatcacattc taaatgatcc gtgagtttgg tcaattgttc gtcatttatt tgtcgatttt
     5641 cagtggtcgc cagaggaaat ctcgaatcgt ttgaagcatg aacatatgga cttttcaatt
     5701 agttttatca cgatctaacg tgcaatttgc aatgatcttt tcgatacaga acccctctca
     5761 cacggcaata aaggcctgat ccgttcattg caccatcgag gaaaaacaag acatacaaaa
     5821 aatcatgtcg agtctcgtgg aaagatttgc cttactcatt cgatccatgg ccgtccaaaa
     5881 tccgcagatg atagaagtga ttttggtcat tggaaagccg atattgtagc tggcaaaact
     5941 ggtggtactt gtttagtgac tttgacagac agaaaatcat gcttcctttt agcaggaaag
     6001 aaggtcccca gaaagaaagc cgcttatgtg agcgagaaaa tgattgaact tttaagcagt
     6061 attccaaatg aggcggtcaa aacgatcact ccagatagag gaaaagaatt ctccaatcat
     6121 ttcgcagtta cagaagcatt gaataatatg cccttttatt ttccagatcc tcatgccctt
     6181 ggcaacaatg aacaaattaa aatacgaata gactcattcg agaatacttg ccaaaatcga
     6241 aagagatagc tacggtagat aactcaacga taaatcagat gattgaaaaa ctgaataaca
     6301 gacctagaaa gtgtttagat tggagaacac cttatgaagt cttctttgat aaagtgttgc
     6361 gcttgatttg acaattcaag acataataaa aagcagatca aatccaaata agggaaaaat
     6421 gatctactct ggtattatca attaattggc caagctatta tgccgttttg ctaaacgtct
     6481 acttcttcca gtattgacct tgataaaaca acaatcagga tcccgtttta atactctatg
     6541 aactgtgtca atactaacat gtaaagttgc agcaatatca gctaatgtac tcccatttaa
     6601 tctcatttgc tttgcaaatc gataacgccg ataagcatca atattcttgg aatccataga
     6661 caataatact tttcttacca tgtatttcct ccaaaaattg aattttaatg agccatcatt
     6721 tcttgagcaa tttcatgttt agacaatgaa gctggataga aagtaggcca attatgcaat
     6781 tcattataga gtttttcttg actttctcca ccaaagaaaa tatggaaatg ctctgcctta
     6841 cttggtgcaa ttccatgatc actaaattga atatatttaa aacgaccagc acctgcatca
     6901 tcagtttcaa aattaaaacg aacaccacgg tttccttttt cataattcaa aattttgtat
     6961 ccaacatatt tgtatgtgta ttgatgatgt tcaccgttga ctacaaaatc aatggtgttg
     7021 tctttaatgt tgatagtatc aatatctgtc ttatagccag tagtataata atctttgtac
     7081 tcggcagctg tcatgtcttt attgattttt gctttgtaat cgaaaacttc atccaaaatt
     7141 ccatctttta acaacggata aacagattgc cattcgcctg tataatcact caattcgcga
     7201 tccttcacat cggcatcttt aaagtaccca ttagcaactg tcttttcatc cttcgcttct
     7261 ttttctggaa ctacctcttc accagcaacc atagttgttt tttctaacgc ttttagattg
     7321 tcttccatta ctgaaacata atcttcacca ttatccattt gttcttttgt aagactttca
     7381 agaggattca gtacttccaa ttttatccca gcttcgttgg ccaaagtttt tgcaatttta
     7441 tcattagcat tcttttcaaa gtaaatataa ttgatcttat tttttttaac atactctttt
     7501 aattcagcta atcgaccaga agatggctct tcttcaggac ttagtccagc aataggaact
     7561 tgtttcaatc cataatccaa agctaaatat ccaaaggctg cgtgttgcgt cacaaaactt
     7621 ttttgtttcg cttctttaag actagtggta tagtcagcat ccaaccgttt cagtttagtc
     7681 aaatactttt cagcatttgt ctcaaatact tttgcttttt tcggatacaa tttaactaac
     7741 tgatccttga tatttgaaac ttccttaatt gccattttgg gtgaaaccca cgtatgagga
     7801 tctagttcat gatggtgatc ttcttctccg tgatcatgat cttcttcttc actacctggc
     7861 aataaaatca tgtcttttgt tccttctact acattaggcc cagctttctt ccaactttct
     7921 ttagcttttg gtacccatga ttccatgttt tcgttatgat atacaaaaac atcagcatca
     7981 tgagcttttg ccatatcctt agctgagggc tcatagtcat gaggttctga tcccgctgga
     8041 accattaaat ccacgttcgc ttcatcgccg acgatgtttt tggtgaaatc atacattgga
     8101 tagaatgttg ttacaatttc taattttcca tctttatcat tcgatacttt tgcatcatta
     8161 gtgctggagc aagctcccaa taatcctaga gctgctatcc caataagtcc tacactgatt
     8221 ttcttcattc tttttccttc cttaattatg ctaatttctt cattttattt cgtttatgtt
     8281 ctttgataat ttttaatgcc ctttttctag ttttaatatt cgggctttta agtcgtcgat
     8341 atgcactaga tatatccgtt ttctccatta gaaattaccc ccaatcacta cttatcatta
     8401 tttgctttcc gccagtaatt tatcaaaact ctgtttgatc ctttcttcat ccaacatttt
     8461 tccgattaga ataatagtgg tttggtcttt ttgtcgagtg gtgtattgaa aattaacctg
     8521 ttcgtttacc tcttgcatgg caactataaa atcctgctct tgtaaagcaa tcaatccttt
     8581 aaaacgatac aggctccctt ggttggttaa aatcagccag tcaatccatt ggagtaaaaa
     8641 atcttttttt atgtcttgat ctgaagttaa gagaattgat ttaaactcat gtacttgatg
     8701 gtgttgatga tagtatttgc cattatagtg attttctgat gaatcacttt caaaaactaa
     8761 gggatgatta aattttttca aattataaaa atcctttttt tgaatcgttt cactatgtgt
     8821 gaacattcga atatcggata aagggttaat acttttgatt tctctctgta atttttttag
     8881 tgcagataaa ttcaagtttt gttttctaga cacaaaaatg cgatctgcca tgacaagttg
     8941 cttaagggct tgtggttctc tttcaataag ttcaaaactg tcactatcaa taacagtcaa
     9001 taaactatcg atatatactc ttcctcttag ttgaggcgct gttaaaagtg tttgaatgat
     9061 tggttgggga tctgctatac ctgtagtttc aatgatgatt tgtgaaattg gttgttgatg
     9121 ttcttctatt gtttccagta aagaaatcaa tattgctaat aaatcactgc gaagactgca
     9181 acacatacat ccattattta gttgtaacac ccgttcctcg ctatgaacta ataatttgtg
     9241 atcaatccca acttcaccaa actcattttc aattataata atttcttccc tggggtaggg
     9301 tgagacttgc aaggcttgat tgattagcgt tgtttttcca gcccctaaaa acccagaaac
     9361 gattgtaact ggtatgccca ttttgtcacc tttttaccac ttagctattt cacttcttta
     9421 aaaattgccc gtctgcgcaa ttttggcgaa tactttttta attctaaccg ttcagggtta
     9481 ttccgtttat ttttgctggt gagatacaga cgttctccag tttcgacaca ttccaaaata
     9541 atattttgac gcataaatct tcctccttca atacttatcg atcttcaaga tatgcttgaa
     9601 tttgttgtgc atcttcaaaa gttaactcgc cagattccaa ttgtgaaact aaattttctt
     9661 tcatatcaac aggtatctcc caataaccat cgatacattg aaataactcc tcgtcatact
     9721 cttcaaaaat tggatagatt cttaaaaaat catcaaatga taagccttgg tcctcatagt
     9781 aatctttgac taatccattt tcaattgcct gttgggtcgg taaacccgtt tcagtaataa
     9841 ttcctctctc taccatcgaa cgataaaaag tgcatttatc tagcgattgc tgggtcgttt
     9901 caagataata ctttaatcct tcttcaacta aaggtgggta aataatttcc attttgattc
     9961 cctcctaaaa gttatatatt aaactatttt gaagctcctt taattacttt ctttccatta
    10021 tagtaccctt ttaaagatac atgatggcta cgtctataat caccattcgc ttcgtcaaat
    10081 gaaatttctg gttttactac agtttgatga gttcttctta accgtttctt cgccttagat
    10141 gtttttcttg ctggtactgc catgatattt cctcctttta ccaacttgct ttttttactc
    10201 caggaatcaa cccttgatgg gcaagttctc taaacttaat acgggacata ccgaactttc
    10261 gcatataccc tcttggacga ccatccgtct gatcacgaag cctcagacga ttcggatttg
    10321 aatctcttgg caatttagcg agagcggtgc gatctcctgc ggcttttaat tcctgacgtt
    10381 tatctgcata cttttcaatc atcgccattt gtttctttgc tttagcaatt ttcgactttt
    10441 ttgccatata cctttatact ccttttattt tgatttagac acctcaaatc gtaatcgtta
    10501 cgttttgaca ctgatacttt accaacaaga gttgctcttg tcaacaataa ataacatgaa
    10561 ataaaactca tatgaataga taactatttg aaaacgaatt tatcggtaca tagagataat
    10621 caaatcattt aaaagaatat gcagtttagg ctctgaaaaa taagaattca cttttattag
    10681 tccaatcaaa cacaaatacc gttttaagta gcttttcctc tacttaaaac ggcaatatga
    10741 aagaaactat aactttttat tcaatctttt atgtttaact ggtttatcgc caatttttta
    10801 aaactttgat tattccttat attataagaa tagacattaa gtgaactaat tcaatcatac
    10861 tgattctttc gtgtattcaa aattagatgc tgtttaataa aattattctt tttgaaaaag
    10921 aattataact atatcccaaa aattgtaggt taatttaaag cctatttcat catcgtgatt
    10981 gagcttcttt ttcatagacg aatttctcag atagtttagt tttctttatg agatttttgt
    11041 atatttctga ccttcgatac aactcattat gagtaccttg atcaactagt tttccttgat
    11101 ccatcactac aattttattt accttttcaa tagacttcaa gcgatgcgat ataattagta
    11161 ctgtcttatc ttgtattaaa cgatttaaac tttcctgaat acgtttttca ttttccgcat
    11221 ctaaactggc agtaatttca tctaaaatta aaattggcgc atttttcaaa aaagcccgtg
    11281 ctatggatag gcgttgtcgc tctcctccag aaagtgaact tccgttttct ccgaccaatg
    11341 tatgataacc gtcaggtagt ttttcaataa agtcttcgca gttagctaaa cgagctgctt
    11401 ttttcacttc ctcatctgac gcttgactat ttccaatacg tatattttcc aaaatacttg
    11461 tattaaacaa agttacctct tgaaaaacaa tagcgatttt gctaaacaaa gaagctggag
    11521 atacacgttt aatatcatac ccatcaatta aaatacagcc ttcatcataa tcatacagtc
    11581 tagacactaa tttcaagata ctagttttcc cggaaccact agcacctact aacgcagtca
    11641 cttctccttg tttagccgta aaagagatat gatctaaaat tggggtattg ttatcatatg
    11701 agaaagagac atctcgcaac tcaatgtcaa aagatttcag aggactatct gatccctctt
    11761 ggatactggt ttccttcata gctctaattc gctgtatttt aggagctaaa taaaatattt
    11821 caagcactgc ttctttcata gaatcgaagg aatcctttat ttttattgcg gctagtaagt
    11881 aaccaacgac gtagagtata gtcacttcac ccgttaacag taagtgaaca cctactagaa
    11941 tgactactgc taaactaaca tatgagaaaa tagaggataa ggccatgact gaaaaagtac
    12001 ttaattctac ctttaaatga atcctttcac tctcttccat ttttttgaaa agtctgtctt
    12061 gaactttttt agatagatta aagctattaa tctcttgctg caattctata gtttcttgaa
    12121 attcttccga gttctctctc aaagtatcgt aatatttagt attggctttc gtttgggatt
    12181 tctttgataa caagattaag acaaaactaa ataacgttgg caaaataaca gctaatccca
    12241 ttttgacatt accaaccaaa agcatcactg aaataaaagg gaaaaacaga gccataccgc
    12301 cggctttagg tattgcatga ctcatcgcat gctcaatacc ttcaacgtca gacatgatag
    12361 tttgagataa atctgataaa ttatgttttg aaaaatagga taatggtaaa tttgacaaat
    12421 cgtctgcaat ttgcactctt aaatgcgcac tttctttata agtactatta tataagtttt
    12481 catactccct atctaacaac caatacatga aaagcaaagt aacaaacgat acggcaaaat
    12541 aaagccaacg gggctttgta ttttctaaaa ctaattcgtc tatcagcatc attataatga
    12601 atgctggtac catattaatg cagtatacaa aaaaactaga aatagaagct ttagttaaag
    12661 cttctgcgcc ctgatcactt aaagcaaatt tgtttttata aaaacttttc attgtcaagc
    12721 ctccaatcat ttgcattctc ataattagtg accaattgtt tatacacttg atgtttagcc
    12781 attaattcat tatgatttcc acgttctact attttccctt ctgacaagac aagaatttca
    12841 tctacagatt taatgctgga taatcgatga gctatcataa taactgtttt ttctttcatc
    12901 agatgttgaa aagccttttg tagttcatac tcattatctg gatcaataga tgcactggct
    12961 tcatccataa taacaatctt tgcatctttt aaaattgctc tggcaatagc tatacgttgt
    13021 ttttctcctc ctgacagata aactccttta ctaccaatta aggtatgctc tctttcggga
    13081 aatttttcta aaatcgattc gcaaccggct aatcttagcg cgtcaaatac tttacttgct
    13141 ggcgcttgag gatttgctat agaaacgtta tcgtaaatac tctgattgaa tagtttcgta
    13201 tcttgaaaga caaaagcaat tgtgttaata attgtgtctt ttgaatagtg atttaaaggc
    13261 ttaccaccaa ttttaatctg tcccttatcc acattgtaga aacctgaaat tagtttagct
    13321 atcgtactct ttccgcttcc tgattttcct actaatgcat aaattctttt ttgttctaaa
    13381 actaagttga aattttctaa aacacactct tctttgtatg aaaagctgac attttcaaat
    13441 gcaatgtcac aatttttaat ctgtgtctcg ttcccatatt ttagttggtc ttgcttcatt
    13501 tctaaataaa gggagtctag tgtttcgact gcatatcttg cttcaaacaa gtgcatactt
    13561 acatacatta ttctcatgaa agaaacaaaa ataattccac ttaaaaaaaa caacatcaac
    13621 aagtcaacag ctaatatctt gggagtggta agagaagtta taaaaaaggt tataggaact
    13681 atcaaaatgc aaactatgcc aaaaaatagc cattgaaaaa gaacaaaagg tgttttccca
    13741 ctcaaagaat acttatatgc aaacttagca taatcgttaa ttgctttatt caaggcttta
    13801 aatgatgtta ctttagcacc aaatatcttt ataacttgaa ttccgcggat atattctacc
    13861 gtttcagagc ttaacacatc taacgattct t
//
LOCUS       DADVXE010000070        13771 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.071, whole genome shotgun sequence.
ACCESSION   DADVXE010000070 DADVXE010000000
VERSION     DADVXE010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.071"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(266..958)
                     /locus_tag="KB913_002290"
     CDS             complement(266..958)
                     /locus_tag="KB913_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6820625.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1395..1964)
                     /locus_tag="KB913_002291"
     CDS             complement(1395..1964)
                     /locus_tag="KB913_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6820626.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(2038..2361)
                     /locus_tag="KB913_002292"
     CDS             complement(2038..2361)
                     /locus_tag="KB913_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820627.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2515..3327)
                     /locus_tag="KB913_002293"
     CDS             complement(2515..3327)
                     /locus_tag="KB913_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820628.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3680..4528
                     /locus_tag="KB913_002294"
     CDS             3680..4528
                     /locus_tag="KB913_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBB6820629.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4673..5614
                     /locus_tag="KB913_002295"
     CDS             4673..5614
                     /locus_tag="KB913_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBB6820630.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5604..7775
                     /locus_tag="KB913_002296"
                     /pseudo
     CDS             5604..7775
                     /locus_tag="KB913_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7887..10058)
                     /gene="copB"
                     /locus_tag="KB913_002297"
     CDS             complement(7887..10058)
                     /gene="copB"
                     /locus_tag="KB913_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBB6820631.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(10078..12264)
                     /locus_tag="KB913_002298"
     CDS             complement(10078..12264)
                     /locus_tag="KB913_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBB6820632.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12264..12473)
                     /gene="copZ"
                     /locus_tag="KB913_002299"
     CDS             complement(12264..12473)
                     /gene="copZ"
                     /locus_tag="KB913_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBB6820633.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12486..12926)
                     /locus_tag="KB913_002300"
     CDS             complement(12486..12926)
                     /locus_tag="KB913_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBB6820634.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(13000..13539)
                     /locus_tag="KB913_002301"
     CDS             complement(13000..13539)
                     /locus_tag="KB913_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6820635.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3886 a         2865 c         2437 g         4583 t
ORIGIN      
        1 ttttatcaaa gttttattat acttgtcaat ttgtgtacat cctaaaatat aagctatttg
       61 tttacttctg tagaatatat actttgttgt tagataagtt gcacatgttt atagaatcta
      121 aataataaat ttttatgtac cgcccctcaa agtgaactga accccaaaag ttgaactatt
      181 taatggactg tttccgatat tctactggag atagtccatt aaatagttca acttttgggg
      241 ttcagttcaa agaggggggg attttttatc gttgtggaat atttaaatac caacgcttgt
      301 catgaaaatc ttgtgctcca cccttagtat ttccttctgg atcgtttgtc gcacgcatca
      361 tgacgtatac tttcttatta gggaaatcac gcatattgaa agatacatga tagccaacat
      421 ttcctaaagt attataagct tgatttacgt ctggtctata aatcccatca gctcttactc
      481 tagctagttc ttttccagta ttgtagtcca taatgaaaat atactcgtat ttataattag
      541 caatgtgcca tccagctaca tgcaagtttg cgttttcgat ttctccgaac tgatcaatgt
      601 gggcgtaatt tgttccatct gtcagcgtag aatttgcagc acctgctcga gttggatcaa
      661 ttactggttt atcctccgaa gtagttggat tatcatccgt aaaaccatga gccaaatcat
      721 aggctagttt ttctttactt acacccattt cagaaagata accgtaagga tctgtatgat
      781 cgccccaaat attttgtgtt acccataaat gcgatttgat tcctggttgg ttataaggag
      841 tgtctaatgt taatggaata ccatatttca ttgctgaatc tcttgccaat tcaacgtata
      901 ctttatagtt cttttcaaaa gtttctttat catgtgtatg ttgtaactcg atttgcacag
      961 gacttttggc tcacgaggtt gtcctactct acatcttgct gatagatatg ctgaaaggaa
     1021 aacaccaaca ttatgttttg ctttttcagc tagaacgaga caagcaggaa tacctttaga
     1081 agatatcaaa ggttttttag gtcataaaga tgtttccact acacaagtct atgcccatat
     1141 ttctcccgaa gtgaaaaaaa gatcaatgaa tcaactagaa aactatatag aagagcaaat
     1201 aaaaaagcac tcaaattgag tgctttttta agctcactat cactaaaact atcactaatt
     1261 ttatttataa gcgaacatgt ttctatcact gattttttaa atctagcgaa aaacccttat
     1321 cttaaaggcg ttcgttcaat tctttggcaa ggtcttcaaa gcctggcttg cctagaagtg
     1381 cgaacatggt tttcttatag ctcatgtaga aaaattttct tgatgatgat tttatccatc
     1441 aattgagatt gactgttttg ctctcctatg atttcagcta tgattgtccg attttgcggt
     1501 tttcttctta actggtagtt gattttccca gtttccatca actcgctaag catatccacg
     1561 actccgccaa atccggtctt tttcgtaata aaacctagtg ctaccattcg ttcatctaga
     1621 ttttttgctg taatcgtcac accagtaatg agcgagtgct gtaatgtttg ggccagctct
     1681 tccatccctt cagcattgga tacgacggaa gctgttttgt taataggttc ttcgtttatt
     1741 tcttttggtt ctttcctctc cactttcact gtttgacgaa ggacatctag ttcttgcaag
     1801 agcgtttcgt attgttcttg ggtcagcatc acgccagcta ctttttcacg attaaatata
     1861 tatacgccag ttcccgcgtc tcgcgcttga gcaaatacat ccatcggcga tcgtttcact
     1921 tctgtgatcg aagatgtggg aacttctaat ttctttaatt ccaatggatt tcctccttta
     1981 ctaatcgctt tttattatag cacagactga cttgttttga tcttttttcc aaaggtttta
     2041 tcggtttttg cctaaccagt aattgatatc ggtaagaagt ctttcgatac caaatgaagg
     2101 atggtacaga tacgtttttt gatcttcgtt atggtctagt ggaaaaaaat gatcgatgat
     2161 cactagatct gcataccgag gcggcttatt tcgagtacat acatgtatag agatccgttt
     2221 tcgatgtctt agcgttttgt tcagtacccc agcaagtctt cttgcttctt ggtgttcata
     2281 gcgaaaaaaa aagacgattt tcacttcagg agggtggaca tctaaatacc ctcgttcctg
     2341 gagtgttttc agtaaaagca tcccccactc tactgcgggg tgtgcaagtg cttgttggat
     2401 cgctagccga aattgatata gtttatcttt ggaattggga aatttttcta atgtttcctg
     2461 ataataacga acttcttcta tcagccggtc atggatacca attacgtaac gaagtcattc
     2521 ttggtaaagt acttttgtca gctttgattt gctttcgctc tcaaattcgc tattcagcca
     2581 aaacagcgaa tcaagctttt cagtcacaat cgtcaatttc cgatagtctt gtgtctcttc
     2641 tatccgtttc caccgctttt cagtaatctg gttacagctc aagcgcaaaa ttgctagata
     2701 atttttttct tttattggca aaatctgctc ctctctaaat agcaattcag gaaacaattc
     2761 aaagaatagt gttcgactgt ctcctaaaat ctcgatttct gccggatcct ttctttgctt
     2821 caataattgg atgaacatct cagaaaagga ctgctctcca tcatctgcaa aaaaatgcgg
     2881 aaaatctttc aaaaagcaaa acagcagata tcttactttt ctttctgaac caaagatctg
     2941 tgctttttta taagaaaaag aaaggtggta ctcgccaaac cactttctca atcgctcttg
     3001 cgtagaacga tcgtacttct gctcgtaagg ttcattcaat agcagatttt tcagtaaaca
     3061 aaacgggggt gattggatca gaaaaacaaa caagagataa ggttcgctat atccttgatc
     3121 ataaactaac tgaacggttt tcttatgaag aatcagctga atgggacagt cgctttccgc
     3181 caaacgtttc agatgccgat ccactgtttt aacatcgatt ttcagttctt cagctaaatc
     3241 agcttttcgc cagatcaaat ctttcattag attgattagt gaaaataaat tctgtgcatt
     3301 ttttgataat agtttttgcc atctcatcga tcatttctca cctgatttct aaacatattg
     3361 tttgatcaaa atgggttcac tcctaaaaag ataaaaaact ccctttctat ttatttaaat
     3421 acgcaaatct tcctcattat tttttatttt actcaattta atcgtattct catttcaaaa
     3481 cgaatgtact ttaaaaaaca taataagatc actttgcttg taggatgtat tcccttccat
     3541 tacaatgaaa taaatagcga ttttatgaga aggtgatgtg aaaatggaag aaaaaataga
     3601 agaatccaaa caaaaaatcg atcagttgat ataagaatta gaaaaagcgg tcatcggcaa
     3661 acgttcaact atccaattga tgatcgtggc cctattagca ggtggtcatg tcttattcga
     3721 agatattccc ggtgtaggta aaacgttact ggtcaaagca ctagcaaaag ctgtacaggg
     3781 aaccttcagc agagtccaat gtactcctga tctgctgcct agtgatattc ttggtttttc
     3841 cgtatacaat tcacaatcaa aagagtttga atttcgtccg ggaccgatct ttaccacgat
     3901 cttgttagca gatgagatca atcgtacgac tcctcgtact cagtcagcac ttttagaagc
     3961 aatggccgag aatcatgcaa cgatcgacaa caatacatac cctctagaca atcatttttt
     4021 tgtcttagct acgcaaaatc caatcgagta cgaaggaaca tatcctttgc cggaagcaca
     4081 gctcgatcgt tttttattcc gactacaaat cggttatcct tcttttgatg acgaactttt
     4141 gctacttttg gataaattcg aaaaagtgtt ggataactta aatgaagtat tgaacagtta
     4201 tgaaatagaa gaaataaaaa caaatgtggc gaatgtcttt gtcagtcccg aagtggcatc
     4261 ttatgccttg cagttagtgt cagcaacaag aagtcatgct gccatccagc ttggcatcag
     4321 tccacgagga agcctttcct ttattcaggc agcaaaagct tatgctttaa tccatgggag
     4381 aaattacgtc acgcccaaag atttgcagga tttagttcct tacgtgtttt cccatcgcct
     4441 gattttttac gatcgttcat tgaaggaaga cgaaaagaaa caaatcattc atactcttgt
     4501 tgcacaaatt cctattcctg tgaggtagat tgaggtagac aatggaaaaa atcaaagatt
     4561 atttcattaa ttttgtgtta tttctggtat atttcatcat tgtgcttttt gctcttgtat
     4621 tcaacaattc tttaggctgg ttcttgttgg ccttttttac tctttatgta tcatggagct
     4681 tgatttcatt aagcagcttt ctaaagaaac tttcggttac ttgtacattg cagccactcg
     4741 tttatcgcaa aaaaagtatg caggttattt tttccatagc aaaaaagaga actttttctt
     4801 tacctctccc tcgtttacaa atcggcttcc cagcaatctt tgcagaaaaa aacaagagat
     4861 tttgattctt acaaataaac cgcaagaagt ccaattgctt tggcagccaa aagaaagagg
     4921 atgccatgaa acattaactg tcatttttac agcctatgat agtctaggac ttttcagaaa
     4981 aagtgcaaaa agagagatct cttttcctgt gactgttctg cctgcttttt gtaagattca
     5041 agcagaaaaa ttacagagag ttctggaaaa aaaacagcag ctgaacgcgt accaaagagg
     5101 tcttgatttt cgggaacatc gcgcttatcg tccaggtgat tctttcaacc gaatcgattg
     5161 gaaattgtct gctcatactc aagagtggtt ataccgtgaa tacgattatc aagaagaaga
     5221 atgttctcct cttttttgct tttggggttc gcccagtcca aaatttgaac ctctgctaga
     5281 cttgtatttt tctttatggc atttgagaaa agaaaagcag ccggaacttc tgatattagg
     5341 caaccgcgcc tttcatggca aagaccccgg tcatacctat tttgcttctt tggaagctgg
     5401 cgatgagaaa gcttttttcg cacacttgaa aaaatatgca aaaaaacaaa tcgtcctctt
     5461 tgttcctgag aattctcctg aagtctcaga agctattgaa acattgtcaa aagatcgaac
     5521 ggtttatctt gtttatttcg tagaaaaaca actcatggtc caagaaaaag acaagatatg
     5581 ttcattgcca ggaggtgaat ggattgacga ttaaacggga aaaatggctg cgtggcgttt
     5641 actcctttgt gatactaagt gtaggtgctc cgatatttgt agtagctaat caattgcaaa
     5701 acagctacct tcttatccta actattggtg tcctatgcct tattgtctgc tgtattccta
     5761 aaaaatgggt acgtttgctg ctttctttgc cagtaatgat aggttgtttg tttttatatt
     5821 ttccttcgaa gacattttcc atattatgga tcttacagtt tttttcgtca gtcacagagg
     5881 aattcttcca tctatcccaa ggtaaacttt attatttgcc agaaaagaca gctttttttc
     5941 tcataatgtt gctgatctat ttatttatta cattgaccgt ggattacgac tattggtacg
     6001 caccctttct ttctttgatg gcttacttca tgatgcttac cgtttttcgg aaaaaagatt
     6061 tactgtacga aatgattgcg gtagtaactg ttttgttcgt gtatctggca gcaaggcaat
     6121 ttttctccat ccggttgttg tcgggaaaca ctcgattcca gtcattgact acagttctgc
     6181 ttatttgttt cttaactttt agcgctatct tgcctttata tcttccgaaa gtacaccaat
     6241 ctctcgagga aacgagtgaa ccgatccgag aatatcttaa tgatgaaggg ctttatgaca
     6301 cactccatga gtatcaatta accggaagtg caagaacagg cttcagtgag aatgatgaac
     6361 agcttggtgg acctttatat gataatggcg aagttgtttt tacagcgaac caaaaaggaa
     6421 atggctattg gaagatcgaa aataaaaatc attacaccgg ttctggatgg atagaagatc
     6481 aggacgcacc catccaacca atccaagaat tccctgttga catcacgagc taccaaaccg
     6541 ttatagaaga caaagaaaac attacattga ccctaaaaaa acaagttttc ttaccttatc
     6601 cttatggaaa tactaccttg actgattttt cattagctag tggacaaacg ctttactatt
     6661 tgcctgaaag ccagcgattc attcctgtcc cgaatgaatc gacacgttct gcaactttac
     6721 aaacagaaag gttagttttt acgagagaag aattaaaaag cagtcagtta aaagctgatg
     6781 atttagaaaa tcagcagaca aatcttcaat tgccaaaaag tttgcctaaa cgtattgagg
     6841 acttggcggt cgaattgacc aaaaatgaag caactttaat tcgtaaagtc gaagctgtct
     6901 aacagtattt aaaaacaagc ggaaatttcc gctattccaa aacggatacc gggcatactc
     6961 caaaagaaca cgattatgtg gattatttcc tctttgattc aaaagtcggc tattgtgaca
     7021 acttttcaac ttctatggtc gtccttcttc gaacacttgg tatcccagct cgctggacaa
     7081 aaggttttac aaatgggctc agaacaggca cagataatca agggaatgag gaatacagca
     7141 ttctcaatag tcatgctcat tcttggccag aggtatactt tcctggattt ggctggcttc
     7201 catttgaacc aaccccttca tttgccaatc caatgggttc acaaccagtt gctgaaacaa
     7261 ccgaaaccgt ccagcctgct atcgaacaac caaatgaaag cgaaaatatg gcagaaacta
     7321 tttccagtga gagatctgag gtcattccat cagaagaaac aacactcaca ccagcttata
     7381 aaatcgtctt attcagcctt ggagtgtgtt tatccgtctt gttgttcttt ctattgttat
     7441 tcagaaaatc tctgcgctgg acaagttatc ttatctatct tcattttttt gcttctacta
     7501 atacgattgc atatcaaaaa cttcttaacc ctttggaaac attggtaccg cgcaaacccg
     7561 cagaatcttt gcaggaatat agcctgcgaa tagaacaaga attcaagcta gatctgcgtt
     7621 tcattcgatt aactactcaa tatgaagcag aaatatatgg acgacaagca gatccggtaa
     7681 aattcgataa aaaaacctat ttagaaataa cgcatataat aagaaaaatg gtatacaaaa
     7741 aaattctgac aaaagggagc cgcttcaaaa aataagataa aatttctgga gaatctactt
     7801 ctggaatgcc gagaaccagc tgattgagta tcgattactc gaaaaaaagg ttgtgacacg
     7861 ttttttgtca caaccttttt tcattattat ctgattttca atgtcaaagc atttagagct
     7921 acaactaccg tacttaacga catcaagaca gcaccaactg ctggacttaa tatgatacca
     7981 attggcgcaa gaattccggc tgctagcgga attgcaagaa tattgtaacc tgccccccac
     8041 cagaggttct ggatcatttt ctttcgcgtt tgcttggcta gatcaagaaa atgcaaaata
     8101 tcttttggat cgctgtttgt caatacgaca tccgcagaat cgattgcgat atctgtccct
     8161 gcaccgattg ccatcccgat tgaagcacgg gctaaacttg gcgcatcatt gatcccatca
     8221 cccaccatga ttactttttt cccttggtca aggtatttct ggacaacagc ttctttatca
     8281 tctggtaata aaccgccata atattcttcg atccctaaat aatctgctac tgcttgggca
     8341 gcgtttttat tgtcaccagt aagcatgaca ggagtgattt ttctttcttt caatgttcgg
     8401 ataaattctt ttgcttctgt ttttactacg tcacctaaag caacgattgc agctagatga
     8461 ttttctaaaa tcaggaagct gatggtattt ccttgttctt ggtaaggttt caataatgct
     8521 tgttctacgt ttaatccgag acgctcaact tctttttcat taactatttt cacttgttgt
     8581 tttttgactg ttgcctctag cccgactcct gaaagatttt ttagattttc agcttgataa
     8641 ggcttgattt catgttcttt caaataattc ataatgccaa cagccaatgg atgattggca
     8701 ttcgcttcca aggctcctag atattgaagg atttcatttt tattgaacgc atcatcaagt
     8761 acttcgacac ccgttacagt aaattttcct tctgttagtg ttcctgtttt gtccagcatg
     8821 atcacatcta gatcattggc ttgctccagt gcattgcggt ttttcaaaag taatccgttt
     8881 ttagctgcta ttgatgtgga acgagcaaca actaatggga tagctaaacc tagagcatga
     8941 ggacaggcga tgataaagac tgttaccata cgttctaatg cattaggaag atctgtcaag
     9001 aacaaccagg cgatgaatgc caggataccc acaattaatg cgacataaaa cagccatttt
     9061 gccactttgt cagataatga ctctagcttg gatttttctc cttgtgcttt tcgcaccatt
     9121 tccataacct tcgctagata accattttca ccagttccag ttacttcgat ttcgatcgtt
     9181 ccatccccat tgatagaacc gccaatcact ttgtcattgg cttgtttttt gattcctctt
     9241 gattcgccag tcacagctga ttcgtcaaca attgtttcac ctttcaagat tacaccatct
     9301 gttggcattt tatcaccaga ccggacgatc aaacgatcac cttcgtttac ttctttcaat
     9361 gaaactgtct cttcttttcc atctttcgtc aagcgtttca ctgattctgg cagtaattct
     9421 gctagttttt gtaaagcatt gctggcattc gacacagcat tcatttcaat ccagtgacct
     9481 agtagcataa taacgatcaa agtagccaat tcccagaaga aatccatgac gtgtgtatgt
     9541 ggattgagca gatttgcgat aaacgaatag acactataaa tatatgcaac tgtaatcccc
     9601 atcgcgatca gtgtcatcat agcaggactt ttttgtttca attccatctt agctccactt
     9661 aaaaatggct gaccgccata gataaatagt atagttgcta agatcaatac gagccaatca
     9721 gaaccaggaa acgttacttg aaatggaaat tccattccca tcattggtga aaaaagaatg
     9781 attgggatag ctaggataag cgatagccaa aatttttgtt tgaaattccc catgtgcatg
     9841 gaatgatcca tgccgccgtg ttcgtgatcc atgtgcatcg aatggtccat ttgtttgctg
     9901 tttgctatat ctccatggtt atgtcccatg tgcatggaat gatccatctg actatggtca
     9961 tgtttcatct ccatctgttt ttcatgagat tctgtacttt ctttgtttac tacttctttt
    10021 ttatgctcat gttttttctc catatcgttc ccattcattt ttactccatc ccttctctta
    10081 ctttttcatg tgtcgattta agcacaggga gttcaacaat acactgacgg aactaaacgc
    10141 catcgctcct cctgcaatga ttggattcaa aaagcctagt gcggcaaaag gaataccaat
    10201 cgtattatag acaaaagccc agaaaagatt ttgtttgatt tttctcaatg tcaacctaga
    10261 caactcgatt gtttgtgcaa tggatgccaa actgctattc atcagcgtca catcggctgt
    10321 ttccatcgca atgtccgttc cacttcccat tgccataccg acatcagcta atgctaaggc
    10381 cggtgcatca ttgattccat cgcctgccat accgactttt ttgccatctt tctgaagttt
    10441 ttctacgtag gctgctttat cctctggaag tacttcagca aagatatgct ttggatcaat
    10501 accaacttgt ttaccaatcg tttcggctgc cagtttgttg tctcctgtca gcataaaaac
    10561 atctaatcct ttattctgga gctgcttgat tgcttgtttg acttctagtt tgatttgatc
    10621 agccacggca atcaacccga tcacttgctt ttcatcagct aaaaacatga ctgtttttcc
    10681 ctgctgttct aattctaacg cgtgttcttg gtattcatca aatgataggt tcaattcaat
    10741 taatcgttta cgtgtacccg caaaatagcg tactccgtta atcgtaccgc tgattccagc
    10801 acctgggtgg gctgtaaaat caatcatatc gtatgttgct gcttcttgca gttttccgta
    10861 ttccacgatt gctttaccta gtggatgttc agaagcttgt tctaaagtat aaaaaataga
    10921 taggacttct ttagaaccga ctagatctgt aactttgggc tttccttctg taatcgttcc
    10981 agttttatcc aaaacaatgc tgtctaagtg agcagctgct tctaatgctt ctccgccttt
    11041 aattaaaatt ccatttcgtg caccaacacc cgttcctacc ataatagctg ttggagtcgc
    11101 taaacctaat gcacatggac acgcaatgac taatacagag acactatgga tcaatgcgag
    11161 ttgccaatca ccagtgatca aacctgtagc tatgagcgtg ataaacgcga tgactaatac
    11221 gatcggaaca aaaatccctg agatccgatc tgcgattttt tggattgggg ctttgctccc
    11281 ttgagcatct tccaccattt gaatgatttg cgctaatact gtctgcttgc cgacttgtgt
    11341 aacttccatg tgaagtagac cattcgtatt gattgtcccg ccaaagagcg tgtcatccgg
    11401 attcttttct acaggaagat tttcaccagt aagcatactt tcatctatcg cactgcttcc
    11461 tgaaataatt cgaccatctg ctggaatctg ctcaccagga cggatgacta gttgatcacc
    11521 aacgactact tcttcaatcg ctaacgtttc ttctttcccg tttcttatca cttgggcggt
    11581 ttttgtttga agagacatca attgtttgat tgcattacct gttttcgttt ttgctgtatg
    11641 ttccaaatat ttgccgagca aaatcagcgt gatgatcata ctgctgcttt caaaataaag
    11701 atcttggggg tgtccacgga aaaatccgtt gtaaatgctc aatgcaaagg cagccgatgt
    11761 tccaattgct accaatacat ccatatttgg tgctttcgtc ttgattgcat ggtacgcacc
    11821 tttataaaaa cgagcaccga cataaaattg gacaggagca gacagcacta actggacgat
    11881 tggaaaatga aaaaagtgaa caatcgccgc atggcttcct aacatcatag caatcattga
    11941 caacatcaac ggcaaagtca aaaccgtact caatataaga tcgaatagca tttttttcaa
    12001 atacgcttgc ttttcttctg caattttttg tttgtgggct tcatcgtaca aaattgcacc
    12061 atagccgatg ttttctacgc tttggattaa tttttcagtg gtcgtccctt catatttgac
    12121 acttgctttt tcagtggcca agttgactgt ggcattgacc acaccaggtt gtccgttcag
    12181 ctctttttcg atcctagcag aacaatttgc acaagtcata cctgtaatga cgaacgtatc
    12241 cattttggtt tctgctgttg ccatcaaatc acctctgctt tataacccaa tccattgatt
    12301 gcttgacaaa tcttttcgga ttgaactttt gtttcatcaa acttgaccgt accgtttgct
    12361 tttttcaaat ttactttcac tttttgcacg ccgtcaagtg cgcttactgt ttcttctact
    12421 cttgctgcac aatgattgca gctcatacct tcgattgaaa attgttgttt cattttttct
    12481 tcctcctatt gatgttgttt acattcacat tgacctggga tacagttaca ttcgatcgta
    12541 tctactggtt gcttttgttc cagttgtttc aaaatctcat tgatatcttc ttgagtcaaa
    12601 gtggcttctt ctactagatc cgcaatcgtc tctccaatcc tttttgcaca gatatgggaa
    12661 aaaagatttt ccgtcgcact gcgaactgtt tccatctccg agacagctgg ataataaatg
    12721 aatttttttc cttcttgttc tgtccagatc acttcttttt ttaccaaacg acccagcaaa
    12781 gttttgatcg ttgctggttt ccaatccatc gaatcagcta agatctgcgt gatttcttgg
    12841 gctgtcgtct gtccaagtgt ccaaataaca cgcatgatct cccactctga atcactgatc
    12901 tttactggcg ttttgacttt ttccatttat ttcacacctt tcgtttacaa atgtaatcat
    12961 tatcttatga atacagatta cacttgtaaa caaaaactgt caattatttt tgctctctat
    13021 tttcaattta gttaaaaatt cttgtttctc tcgtcttgtt ttaaggatga tcagtttatt
    13081 tcttgcatta gctacttgga tcagctgctg tattttcggt tcattgtttt cttcaaaatg
    13141 ccagataaaa gataaaaatt ctaagtattc cctgtttagt ttctccgaaa atgattcagg
    13201 catatctggc cgagattttt tgtttatctt tctttttaga gaacgccaaa ctactcggta
    13261 gatggcgaga taacgcggca ctttaagcca aatgatctta tctgcttctt taatcctttc
    13321 ctctaatgta gaagtataat ttccttcaac gatccatgac ggattagata ccataaacaa
    13381 ttgctgttct tgcaaaaacc acttttttgc ctgaatactg tagtctgttg tatgccataa
    13441 aaggtctagc ggcagtagcg gaaagtcggt gatttctttg atcttccttg cgagggtcga
    13501 ttttcccgac ccactttgtc caatcacgat gatcttcatt cttctccctc acttctcttt
    13561 ggaatttggt tcgatcatac cacttataac gccgcaaaaa aacaagggac tgtgacaaaa
    13621 gtcgtgtcaa agtcccttgt ttcgaataaa ggctctataa tttatgggac tgatgaatca
    13681 gaattgattc ttcagcccca tttttatttt aggtattaaa aaacatatcg ttctctagta
    13741 tgattaaatc acgacaaaat aaacaactga g
//
LOCUS       DADVXE010000071        13526 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.072, whole genome shotgun sequence.
ACCESSION   DADVXE010000071 DADVXE010000000
VERSION     DADVXE010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.072"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(334..894)
                     /locus_tag="KB913_002302"
     CDS             complement(334..894)
                     /locus_tag="KB913_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6820636.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            1036..1650
                     /locus_tag="KB913_002303"
     CDS             1036..1650
                     /locus_tag="KB913_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6820637.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            1839..3719
                     /locus_tag="KB913_002304"
     CDS             1839..3719
                     /locus_tag="KB913_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBB6820638.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            3798..4025
                     /locus_tag="KB913_002305"
     CDS             3798..4025
                     /locus_tag="KB913_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6820639.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            4030..4572
                     /locus_tag="KB913_002306"
     CDS             4030..4572
                     /locus_tag="KB913_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6820640.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            4799..5515
                     /locus_tag="KB913_002307"
     CDS             4799..5515
                     /locus_tag="KB913_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBB6820641.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(5575..7593)
                     /locus_tag="KB913_002308"
     CDS             complement(5575..7593)
                     /locus_tag="KB913_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBB6820642.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(7606..8604)
                     /locus_tag="KB913_002309"
     CDS             complement(7606..8604)
                     /locus_tag="KB913_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820643.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            8802..10043
                     /gene="sstT"
                     /locus_tag="KB913_002310"
     CDS             8802..10043
                     /gene="sstT"
                     /locus_tag="KB913_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBB6820644.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            10190..10825
                     /locus_tag="KB913_002311"
     CDS             10190..10825
                     /locus_tag="KB913_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBB6820645.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            11016..11756
                     /gene="truA"
                     /locus_tag="KB913_002312"
     CDS             11016..11756
                     /gene="truA"
                     /locus_tag="KB913_002312"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBB6820646.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(11901..13499)
                     /locus_tag="KB913_002313"
     CDS             complement(11901..13499)
                     /locus_tag="KB913_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820647.1"
                     /translation="MLFLSFAYVIPLFMSKGIYHSVNQDTYFHLSRIIGLDNVWSSPV
                     NFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFITFLTMVVSYFSMK
                     QIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLILMGCYEIYIRDYQK
                     WYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLLSLLKATVLTFFLS
                     AGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYTIGLFLFLGLIGAF
                     IFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVWRLNGFSSLFIAYT
                     MSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLTLIAPEDAVAIAEN
                     YNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIELDNSNNKNTVLTTP
                     IYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTKLAIASRYLSIVTL
                     ILFLLYRFTFSKQKQPRREVQHSH"
BASE COUNT         4530 a         2135 c         2633 g         4228 t
ORIGIN      
        1 tgattcccct tgaaaatgaa ttgaggtaaa cgagaagaat tcaataaact ggatgataaa
       61 aatataatat gactataaat tggttacagc ttcaacctat aagttgtaat aaattagcct
      121 aaaagtaatt tattaatgat gaggtgaatt tgattggtac aacaagatat atcacttaga
      181 gagggagaag cagcactaca aactactttt caataagtag gaattataga aattttactc
      241 aaaaaatctt cagtaaacaa tttggctaaa taagattcag ttgttatacg agaaggttac
      301 ggttcttctt aactaagctt agtatgtttt tattcaaggc atgattttct ctatgtgatc
      361 attcagtttc tgtaagagtt ctaataattc ttttttggag tacttgtaat tgctttctac
      421 ccaccgattg agaacggata gacaaccttg gacgtggtac gtagtaaaga atctcatttc
      481 ttctgtgata atcgttttct tgtcttcata tagccatatg ttcagatagt tttcttcaat
      541 aacttgttta actttcttct gaaacgaaat atcaccatgg ttgaggataa ataagcgata
      601 taaaaaagta tttgcgtaaa catagtcaat caagcgagtg tatagttcct catagctatg
      661 ggctggatca taagagagaa tttcatttag atcccgaaaa aagttgcttt ctaattgatc
      721 atatagatca tagatatcct tataatgtgt ataaaaagtc gaacgatgta catctgccgt
      781 ttctgttagt tcgcgtatag tgattgcttg aatcttttta tttactaata atgtggatag
      841 tgtttcagcc aaagcttttt ctgttttttt gacgcgtcta tctgtctttt tcatttacct
      901 atctccttat ccgacatatc aaagcaaagc tgtcgcttaa tcgacaaact tatagatgat
      961 tgattataga tagtagacac tgtgtctatt ataatgtaag tataacacaa tcattgaagt
     1021 tgaggaggcg aaatgatgaa actaactttt aaacccttag aaaagaaaga ttacaaaaaa
     1081 gctatctatt ttgctgttga aggaatgaac tttgagagat atatggaaaa tgaacttctg
     1141 ctgaatcttt acggaagata ttttttgtat atggagttga atcgagcaac tcaaattctt
     1201 gctttgtatg cagaggacga gttggcaggt gttttgctgg cggagataaa aggagaaaaa
     1261 aagaaacatc gttcttttgg acagcaaata tatgttaaga tattcgattt tttacaaaat
     1321 atatttgcta aagaaagtaa aggagcttac gagacagcaa atgaacaaat gcttgcagca
     1381 tatttaaaga agcattcgcc agatggagag atcatttttt tagctgcaaa tcctgatttg
     1441 aaaacaaaag gcatcggtac caagttgcta acagaatttg aaaaaagaga gaaaggaaaa
     1501 gaaatattcc tttttacaga tagtggctgt acgtatcaat tctatgaacg acgtggattt
     1561 gaaagactaa aggaaaaaat tagcaagata aaaatcttag ataaagaaat agatctccga
     1621 tgtatgctgt acaggaaaat cattcaatga aaatttcgat agaaacgaca atagttggca
     1681 agatcacttt tagtgagtct tcttgctaac tattttttgt agtgtattct accaaaagaa
     1741 aaccgccttt ttgactaaac ttgatagtgg tcaatttttt atgatggata agtatctata
     1801 cttagtctcg taagaatgaa aggaaaagag ggagaaagat gaaattacaa aagtggatcc
     1861 aagagcatcg aaatcatatc accgccttat cagctgtgtt gattattttt ggttttatcg
     1921 gaaaatttac tggttttgtc ttgttctata acattgctct agccatagct tctattattg
     1981 cggtcatacc tattatgatc catgcgtatc aggcagtgaa agtcaaagtt atctcaattg
     2041 atttactcgt tactattgct gtgcttggtg cctttatgat cggagaatac aaggagtcag
     2101 ctatcgttac attcttgttt ttgtttggta gctatctgga acaaaaaaca ttgaccaaaa
     2161 cgcgggagtc aatcaaggct ttgaccgaga tggccccatc tactgctagt gttgtccaag
     2221 aagatggaac gactgaagaa gtggaaatcg atgacgtgga agaaggcgat atcgtcttag
     2281 taaaaactgg tggagctatt cctgtggacg gacgagtcat tgacgggaaa gggtatgcgg
     2341 atgaagccgc agtgactggt gaatcacgac aagtcgtcaa aatcagtgga gatgaagtct
     2401 tctctggaac gattttagca gatggctacg tgacgattga agcaactaag gtcggagatg
     2461 atacgacctt tgccaaaatt atcgaattag tagaagaagc acaagatacc aaatcccatg
     2521 cggaaaaatt cattgatcga ttttctcagt attatactcc aaccgtttta cttattgcgt
     2581 tggttgttgg tctgattagt cgtgattttc gtttagcaat cactgttttg gttcttggtt
     2641 gtcctggcgc tttagtcatt ggtgcgcctg tttcgaatgt agcaggaatc ggtaatggag
     2701 cgaaacgggg catcttagtc aaaggcggtg aagcaatgga tactttttcc aaaatcgata
     2761 cttttgtctt tgataaaact ggtacattga ccaaaggaac tactgctgta tccactatca
     2821 agaactatac agaggatgaa ggggacagct tagctttagt ggctcgatta gaaacgttat
     2881 ccgatcatcc tctggggcgc gccgtgatcc attatgctca ggagaaagac attgattttc
     2941 aacaattagc agtcaaagat aatcagacaa tcaagggaca aggaatcaca gctgagattg
     3001 atggtcatac agtttgtgcg ggcaacacca aattgattgc cgctcacaaa ctttctctca
     3061 caccaaagca agtacaagat ttacatcaat tacaacaaac aggcagctcg gtcattattg
     3121 tagcaatcga caaaaaaatc actcaaatca taggtgtgtc agatgtgatt cgaccagaag
     3181 tcgctgaaca attagctaag ttgaaacaag caggagcaaa acagttagtg atgctgacag
     3241 gtgataatca gatgactgct gattatgtag ctgatatgtt aggcattgat gaagtccatg
     3301 ctgaattatt accagacgaa aaggttcaat ttgtgaaaaa ataccaagaa caaggattgc
     3361 gcgttgcttt tattggagat ggaatcaatg attctccctc tttggctgcg gctgatatcg
     3421 ggattgctat gggatcagga acggatgttg ctatcgaaac gagtgacgtt gtcttgatgc
     3481 aatctaattt tgaatcgttg gttcatgcct accgcttggc taagaaaact gttttaaata
     3541 cccgtgaaaa tgtagtgatt gccattggtg tcgtcttatt tttactcaac ggcttatttg
     3601 ccgggtttat ttacatggct agtgggatgt tcgttcacga agctagtatc ttgatcgtta
     3661 tctttaacgc gatgcgttta ttgtattttg gacacgaaag caaagaagaa aaatcgtaaa
     3721 acttgataag aatcaatttt tttatggaag ctgtaatcta gaataagact atcaagaaaa
     3781 aggaaggaag aactacgatg aaaaaaatta ttatgcaatt agatacacta gcttgtccaa
     3841 gctgtatgca aaaaatcgaa catgcggttt ctcaacagcc tggggtaagc aatacgaaag
     3901 ttttgtttaa tgcgagcaaa atcaaagcaa actttgatcc agatgaagtc caccctgaac
     3961 aattagctgc agttgtggaa aaattaggtt atgaagtcca atcagcaaaa gtaaaagagg
     4021 cgtaaatcaa tgaatatagt ggaagaaaaa tttgttcaag aaacaaaaca agcagatatc
     4081 gaccatcata aaccaactgc tggcgccatg gtggggcatg tattagcaaa ttttaaatta
     4141 gaagaaatga aattgatcca agcacaattg tatgttttgg gtacatcttc gcaagaatta
     4201 agtacccttt tttcagaata tgctgatcaa gaagcgagat ggttcaataa aatctctcat
     4261 gagttagtga ttgaaaatga aatcgttccg tctactttag aagaagtcat gcgttatgga
     4321 aaaatttacg aacatggtca aaacaaatat ttaccagcct caacaatgtt ggaaaacttt
     4381 gcaaaagatt ttgatttcca aaatgtcttt atcacacggg caatcaaatt agctgaaaaa
     4441 gaagaaaaat atggcttgca acaattgctt gttgaacttt taagtttcaa taaagaaatc
     4501 atctaccaag tacaaagact ccaaggaaaa actgtccgac aagatttgga tgaggaagac
     4561 gatgatgact aaaagtctat gtttcttcaa atacaaatat aaagcgtgag gtaaattgga
     4621 aaatcacgaa gattaaaata aaagaagcac ccgctgatgt attacagaca acatcagcgg
     4681 gtgcttctca gtttttagaa gatttgaaag attgatgaga aaatacgaaa aatcaataaa
     4741 atcacattgc ttatttgata gaataaagaa gtgggagtaa tcgaaaggag ttttttaatt
     4801 gaaaaaaagg attttagtaa caattggtct agcttttttg ttagctggtt gtaccaacgg
     4861 gaatgaatcg aaaaaagaat caacaaaaga aacagcgaaa gcaacagttg caactactac
     4921 aacaactagc acagagagca agtcaactgc agcaagtaca gaaacagcag atacctctac
     4981 ttcgtcagag tcttccaaaa cgactgaaac aactcaaaca tctacttcaa gttcttctgt
     5041 agaggcttca tcttcctctt cagaaagcag cgaacaagtt gaacaaacac tgtggaatgc
     5101 agacaaatcc gcacaattag aggcatttat gaccaaatgg ggccaaacaa tgggacaaca
     5161 atacaaaagt tatacgaatc aaatgagtgt ggacttatat ggtcttaaag tccctcaagc
     5221 tattttgaac ggggagtgga agatggctat tggtggagtg cctgtttctg cagaatggtc
     5281 agaaagtggg acaggtcaag cagactatca aatcacagcc gtctattccg atgcagagac
     5341 agaaccatat ctgaaaaagc acgtctatct attcgggttt cagcaaaatc agccaaaagt
     5401 attggtgaca caacaaaatc aggggaatcc cgataattat ctttacttca acgagacagc
     5461 gaataatgaa ttgaaaaatg gctttaatca aatcgtttat ggacaagcaa attaatgaga
     5521 taaacaaggg gttgtgacat gtcttttatc acaacccctt gctcagttta tttgttagtc
     5581 ttttattttt tgtgtcgccc atgttgcact gtactggtta cctgcaacaa gatcatattg
     5641 tatcagacga taatcttcta gaatttcttt ttgtttctca gttaaatttt tttcttggat
     5701 aatttgacta tcctctgtaa caaagacctg ttttccatta aaacgattag acaagctttc
     5761 tgtaggatca attgttaatg caggtagatg attagatact tctgtcaaca acgcatagta
     5821 aggagttact ttgatattcg catgctcaag agccatagca ccaaagttat taggagcaac
     5881 aacttcttta tttaacgtag ctgcttgttc acgactatac ttgttgttat aaatgaaata
     5941 atctgtctgg tgctgttcta atccatattt tttcgaatca ttcccactat agattgcggg
     6001 taaatggtca ccataaaaaa caaaggtaat cggtttatcg attttgtcga tttcttggat
     6061 gaattttttt actgctgtat cggtatagtg aaggccttgc atataagttt gtaattcttt
     6121 tcttctatta ggaatgacag cagttccttc agcagtgtag ttcaattcac tatagtaatc
     6181 atcataaggc atatggtttt gcatagtgga taattggatg aattgtgacg tttccgtatt
     6241 gctttgtaaa gctttcaagg tttctttgta tgctgaatca tccgatatgc gtgggctttg
     6301 ttctatttta tccgtataag ttaatttatc cggactgtct aaataataga acctgtcaaa
     6361 accaaattta tcaaacactt gttttctgcg ataaagagca gctgtaaaag gatggatggc
     6421 tattttttca tcgaatagat cggtaatatt tggacttatt ttctgacgct ccactagctg
     6481 ggtataaggt gtaactaacg aagcagacag gttactgata ctcaagcctg tcagtccttc
     6541 ccattccatg ttagctgttc cgccaccata accgacggat aacatcaatc ctcctgttcc
     6601 ttctgttata atgcttttga tgtaaggaat agggtctgta ggtactgtca gattagggac
     6661 acgtgcagga tcactgaagc tttcacttaa attgagaacg atcgtctgat tgtttaacca
     6721 gtcacttctt gtttggttga tttcatctgc ctttgtgttg tactttttca ttattccatt
     6781 aattttttct ttcgaatagc cagcaggttc ttccatgatt ttaatgtcga tattgtttag
     6841 gaattgaatg actggtccgt tatcttttac ggcgccttgc tggttaaaga aagtcttgtt
     6901 tactttaaat aaattaaaca gcaagaaaga aggcgaattt ttgtgattaa tgaaaaagac
     6961 acccgaaaaa catcctaata atacagcgat actgataaat cgacgtttcc aatgaatctt
     7021 caaggaatac tgtttttgta gtctacgttg tacaataata ctagtaatca ataataggag
     7081 aaggatcaat ccgcccacga ttaataagac tgggctaacc atcgataata gttctgacaa
     7141 tccggtcagc atttttaaat ctgaaggaaa gacaggctct tcccgcattt ccattttgat
     7201 tactgtcgaa atagtgagca gtaagttaat gatcaaggta gcagtcaagg cgtaccaaaa
     7261 acgattggaa atcaacaata gtaagaagaa aaatcccata ataatgatga ttgtcaggat
     7321 catgggtgct tgtcgctgag taaatatttt taaggcaacc tggatagttt ctttccaacc
     7381 ttcttttggt tctaaaacga aaatctgcac gaaggtaaag cagtaaaaaa atgctgcaac
     7441 taaaaaataa cttttatgaa caaaaagcca atgaattctt tttttccaac gctgagttaa
     7501 ttgttcaatc gaatcaaaag cgaagtattc gatgaaacga tgaatgaaac ggattttttg
     7561 tatataaaat aaaaagataa ctaggaggga cactgctaat aaatatcaaa taaaaaactg
     7621 cccgatattt atcagccatg ccttccctga gtttggaaat tcacgtttca taaatgtaga
     7681 tacgcgataa gaaactaaag ggaaattaca tataacttga gtgacaatca aaaatacagc
     7741 aagaaaattt cctcttcctt ttatacctaa tttatcagat agcatttcta aaaataaaaa
     7801 cgaagagaaa gtataataca ttgcgaagag agaatatggt ttagaaaacc tcagcgctgt
     7861 atctgtattt cctctgatga tgagtgaaat ttgtgtcatc aaaataatca aaccgaataa
     7921 aacaatcaag ctgataaata cttgaggaag cttatagcgg accttttctt tccagttcca
     7981 ttctttcaaa ccataaccca ttaaaaataa ataaaaaatc cataaaatac tctgtccatt
     8041 ctgtaatgca aacgggtctt tattaaatag agtagagcag ccaactaatc caattgttaa
     8101 aaataatagt agatatttaa ttgttgtttt cgataattta tttaaaaatc caactgtata
     8161 aggaatacta caaaaaagca aagtacaaga aacagcataa gtaaagtaat tctgactgat
     8221 aggtgttagg ataagccaat aatcacgaat attcaagctg ccagcttgta cgtaaaaaaa
     8281 gatattgcaa actagtgtgg ctattaggaa tataaaggca aaacgactta aataatgtaa
     8341 aacttttaaa cgggcgattt tttgatattg gtaacccatg taaagtggga tcaaatttgc
     8401 accaataaca acggaagttt gtaaaaatgt atagatgtag aatcgaccag ggtttgttgc
     8461 atatgtagga atagtgactg ctgaaatcaa tatacgctgt aaaaccatca ttatacaagc
     8521 gacaaagatt gtcaggaagc cataactctc cttctttatt tttttcaaga ataaacacct
     8581 cacaaaaaaa ttggacaaaa acataagaaa acgtttcctg ataagttgcc cattaataac
     8641 atcctaactt agaatatctc aaaaaacaac gtgtagacag aaaaagtaca aaattagcaa
     8701 gaaatggttg tttgtattgt tagaattttt agaaaattat acctttagtt tctttgcata
     8761 aaatgataca atgattgtta aaattgtgaa agggtggtca tttgttagag aagtttttgg
     8821 atatgtcgtt agttcaacgt attgttgttg gtattttagt cggaatattg tttggtatct
     8881 ttttccccac atggacattt atttcaatat tgggaacgtt gtttgtcagt tgcttgaagg
     8941 caatcgcacc tattctggtt tttttcttga cgatggcgtc aattgccaag cataaaattg
     9001 ggaataagac attcgtgaag cctattttga tcttatattt agtgggaaca ttgctttctg
     9061 cacttgtagc agttattgta agttcaattt ttactgttcc tattacttta caagaaacag
     9121 tatctgaaaa agcaccgcaa agtttggaaa gtgttttatc tactatgttg acgaatgtca
     9181 cacaaaatcc tgttcaatct cttattgatg cgaattacct tggcgtctta ttctgggctg
     9241 tattgttggg actagctttt cgagcacgtt cagaatcgac aaaagagttg gtggatcaga
     9301 tatctatagc gttgtcacaa gtcgtacaag tgattattgc atttgctccg atagggattt
     9361 taggattggt ttatcaatca attgctacga ctggaatcgc tggattggca gagtatctgc
     9421 agcttttact tgttttgatc ggtacgatgc tgtttgtcgc attagttgtg tacccattcc
     9481 tcacgttttt gtttattaaa gaaaatccct atccattgat tttcttttgt ttgaaagaaa
     9541 gcgcacttcc cgctttcttt acccgaagtt ctgccgcaaa tatcccgata aacatgatgt
     9601 tggctgaaag attgaaattg acaaaagagt cttattccat atcgatcccg ttaggtgcta
     9661 cgatcaatat gggcggtgcc gcgattacca tttccttgat gacgttgact gctgtacatt
     9721 ctttagggat tgaagcacct tttgttttga aagtcctttt atgtattttg tctgctttag
     9781 ctgcttgtgg agcttcaggt gttgcgggcg gttcactgtt attgattcca ttagcatgta
     9841 gtttgtttgg tatctctaat gatgtcgcga tgcaaatcgt cggtattgga tttattatcg
     9901 gtgttatcca ggattcaatg gaaactgcct taaattcgtc aagtgatctg ttgtttactg
     9961 caataggaga gctaggcgcg cgtaaaagaa gtggggaaaa aatcaaattg aaagattgtt
    10021 tagatggatt aagtgaacgt tgaacgttag atatttagta tttttaaaat gattcgagtt
    10081 tttaatgagt tatatagatg ttcgtgtaaa tagaggtttc tgttaaatca agataaagtc
    10141 gtttataata acaattaaaa gcataggtaa ttgttattgg aggcgtatca tggatttttt
    10201 acgtaaattt ggttttttct ttttattatt aggcgtgctg agtgattttt tgactccgta
    10261 cgtattagga ttgtattatc ctgaattaga tcaaatgaag agcgtgatca gtgtatttgg
    10321 agaggtttcc agtcctgtaa gaaaagcgtt tcttatttgg tctgtggttt cagggatctt
    10381 tttcatcctg tcattgcctg cattgtatgc tgcatttgtt agtacatctc gtgtgttagc
    10441 taccctagtt acagcagcca tcgcgttcta tggtataggt gattgtatct ttacaggttt
    10501 gttcagtatc aatacccatg aatcttcgtg gaatgtctcg acatgggtcc ataatatcgg
    10561 atcaggttta ggttacagtg gttttttatt gtttccagtt cttcttttct tgatctatcg
    10621 aaaaaatggg caaatggacg taagccactt ataccttgga ctgtctgtga tcagtttgct
    10681 ttttgcggcg atttatggac tggcaagaat tccttctata aattcttggc cattactgaa
    10741 taaaataggt ttttgccaaa gaatcagttt tttctttaat tatgtgccca ttgcctggtt
    10801 gagtatcttg catctcaaac agtaaaactt gagccgtcaa attgaacagt cagcggatac
    10861 ttcatccggt ggctgttttt tgtttttctg aaatatatat ttccacagtt ttcttgtata
    10921 gcttctgtct tagagaagca aggagctata ttttgtgcta caatcttaaa aaggtagaga
    10981 gaagaccaaa tggaagacag aggagccact aaaatatgag aaacatcaag ttgacaatcg
    11041 aatatgacgg aaaaagatat tcaggatggc aaagacttgg agatgacgat aaaaccattc
    11101 aaggaaaaat cgaaaaagta ttgcatcaga tgacaaatga agagatagaa attattggat
    11161 caggaagaac agatgctggc acccatgcgc gaggacaagt agcaaatttt aaaacaaaca
    11221 cagaaattgg actggcagaa atgatcgact ttatgaatcg ttaccttccg cgggatattg
    11281 tcatcaaaag aatcgaagaa atgcctgagc gcttccattc aagatataat gcggtgggca
    11341 aaaaatacag ctattatgtt tggaacaacg tgattccttc agcatttgag cgaaaccaca
    11401 gcttttattt ccctcaagag ttggatatgg acaagctgaa tgcagcttgc gaaaaattag
    11461 tgggtacaca tgatttcatt ggtttttctg cattgaaaaa atcaaaaaaa tccacagtgc
    11521 gtacgattga tgaattatct atcgaacgaa agggagaaat gcttcatttt acttttgtcg
    11581 gagacggatt cttatataaa atggtgcgga ttatcatggg gacattacta gaaatcggca
    11641 caggtgccat gccgatagaa acaatcgatg aaatatttga aagcaaagtg cggcaacatg
    11701 caggagaaac cgtccctgca caaggtctgt ttttggatga agtttattat cgataaaaat
    11761 actttgataa tggatgaaac gcatgtttca cagtataaat atcgatgtta aataatgtat
    11821 gaagcaaatt aaagaaatat aaaaaaagac tttttagcct gtttatgtgt acagctaaaa
    11881 agtctttctt aaataaaaat ctagtgagaa tgttgtactt ctcttctcgg ttgtttttgt
    11941 ttagaaaaag taaatcgata aagtaaaaat aaaatcaaag taacgataga taaatatctt
    12001 gaagcaattg ctagttttgt gtactgataa gtaataacga ctttatttat acctggagga
    12061 atagttaatt cagttgtgcc aaacttagat aattttgttt gtactagttt gccattaata
    12121 gaagccactt gccctttata acgataaata ggtgtcgtca agacagtatt tttattattc
    12181 gaattatcta attcaattgt aagtttgtta ctcataaaat gagttgttgg atttatttcc
    12241 tggttaccta gtaaatattg atcattatta atcatatcag gatgatagat tgactctttg
    12301 tttgcataat cagtatgatt gtaattttca gctatagcaa cagcgtcttc aggtgctata
    12361 agtgttaatg aatctttgtt agcatggata gaattgctta ctcctgagag atgcaatatt
    12421 agtgcaagaa acgtaaagac cattattttc catgaattat ttttagtaga aaaaatataa
    12481 tagatcacta tactcatcgt ataggctata aataaagaag aaaaaccatt taaccgccag
    12541 acaaattgta gactcttaac tggtgtatgg ttaaaaagtt gccaaggaaa taaattggtt
    12601 gaacaaaaaa gaacaaatac accaagaaag aaaataaata aatcatcagc agttaatttt
    12661 tttataaaaa taaaagcacc aatcaatccg agaaataaga ataatccaat agtatagttg
    12721 ttatagttat tatttaaaat atgtgtcagc atatcactag gagccatacc acttaattct
    12781 tttcccagtg ggactttcaa ttcttgtgct ctagattgtt gaataaaagg aattaagaat
    12841 cccgcactta aaaaaaaggt gaggacggta gcttttaaaa gacttaagag tctagcgatt
    12901 ttttggtccc aaaaataaaa agaaagaaac aacgttcctc caataaatac agaaaccata
    12961 gcgacagaaa gtaaatgagt atacactact agcgtcatgc caatagacaa ccagtaccat
    13021 ttttggtaat ctctaatata aatttcgtaa caccccatta gtatcaaagg caaaaatgtt
    13081 aaagcgacag cttctcccaa tgaagcacga tggaatatgt caatggcacg ataggcggaa
    13141 aatgtataaa taatcgaaaa taacagcgaa atataacgat tgttttttat ttgtttcata
    13201 gaaaaataag aaacgaccat tgttaaaaaa gtgataaaaa aatagtagat attataactt
    13261 aaaacaagat ttcccatcat tttataaaat aaaaaagctg gataaagagt aagccatgga
    13321 taaaaaatat tcatcattgt tccatgatga tcgaagttat tgaagtttac tggagaactc
    13381 catacattat ctagtcctat gattcgagat aaatgaaagt aagtatcctg attgacacta
    13441 tgatagattc ccttagacat gaatagaggg atgacgtaag caaaacttag aaataacata
    13501 aaaatgatat ctattatttg gttttt
//
LOCUS       DADVXE010000072        13443 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.073, whole genome shotgun sequence.
ACCESSION   DADVXE010000072 DADVXE010000000
VERSION     DADVXE010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13443
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.073"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(103..645)
                     /locus_tag="KB913_002314"
     CDS             complement(103..645)
                     /locus_tag="KB913_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBB6820648.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            780..1169
                     /locus_tag="KB913_002315"
     CDS             780..1169
                     /locus_tag="KB913_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820649.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1173..1937
                     /locus_tag="KB913_002316"
     CDS             1173..1937
                     /locus_tag="KB913_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6820650.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIQLMEEASTFLAKNLIKKYK"
     gene            2066..3013
                     /locus_tag="KB913_002317"
     CDS             2066..3013
                     /locus_tag="KB913_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6820651.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3143..3883
                     /locus_tag="KB913_002318"
     CDS             3143..3883
                     /locus_tag="KB913_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820652.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(4174..4842)
                     /locus_tag="KB913_002319"
     CDS             complement(4174..4842)
                     /locus_tag="KB913_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6820653.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            4976..5263
                     /locus_tag="KB913_002320"
     CDS             4976..5263
                     /locus_tag="KB913_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820654.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            5679..7217
                     /locus_tag="KB913_002321"
     CDS             5679..7217
                     /locus_tag="KB913_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBB6820655.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            7214..8179
                     /locus_tag="KB913_002322"
     CDS             7214..8179
                     /locus_tag="KB913_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820656.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            8166..9488
                     /locus_tag="KB913_002323"
     CDS             8166..9488
                     /locus_tag="KB913_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6820657.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      9551..9655
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9729..10472
                     /locus_tag="KB913_002324"
     CDS             9729..10472
                     /locus_tag="KB913_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6820658.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            10487..11479
                     /locus_tag="KB913_002325"
     CDS             10487..11479
                     /locus_tag="KB913_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6820659.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            11491..12228
                     /locus_tag="KB913_002326"
     CDS             11491..12228
                     /locus_tag="KB913_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820660.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            12218..12940
                     /locus_tag="KB913_002327"
     CDS             12218..12940
                     /locus_tag="KB913_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBB6820661.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(13024..>13443)
                     /locus_tag="KB913_002328"
     CDS             complement(13024..>13443)
                     /locus_tag="KB913_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBB6820662.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         4431 a         2295 c         2792 g         3925 t
ORIGIN      
        1 attgatgagt atatgtcgat gttttttaat caaaataata aataaaaact gtctaacatt
       61 taaaatttaa tttagatatt agacagtttt taagtttgtg agttattttc cttgtcgttt
      121 tctcactttt ttagtccaga aaccacctga aatatatttt ggctcataag aaatgataaa
      181 agcacgctct tcgatttctt tgatcaggcg atacagttca cgttcgcttt ttctaggaga
      241 aagtatttcg agaactagcc gctcaccttc cagccccatt gcagaagtct gtgtcacacc
      301 ataaccgtgt tctctcagta tacccggcaa acttttatct tctgcgctat ttgctggcaa
      361 aatcgttgtg accatgatgt atcctaatgc caatttgtct tcaatcaaaa ttccgacact
      421 gatacctact gcgtaaccta acgcatagac aaataaattc agtggattat ctaaacgatc
      481 taaaacaagg gataagccga cgatataaat cgtgatctcg accatactga caagtggagc
      541 aatcagtcga tagcctttca ttgtcaacat gaaacgtaac gtgttcagag tgatataagc
      601 aaaattaatg aggaagatca tccccaacat ttttggatca atcatttgta aaactccttt
      661 catttatata acaacaatat caaaaaaaat cgtaagtgaa gaaaaattga aactttatac
      721 atacaaaaaa atgataaaat gattataata gaattataaa gataggttag gtgattaaaa
      781 tgaaaacggt caatcgtgtg ttttgtgcca gccacgtgct aagtctcctt ctcagtatat
      841 acttaggtgt ctattcgatt caacagccaa ttgaggtaga gaacattgtt tttcagatgt
      901 cgctgacaga tggtttaatt ttaagcgttt ttttcttttt gatactgttt attggtaata
      961 ttttcggtag cgttgccagt tttttgaatt tttctattta tccactcctt tcgctagcat
     1021 taggagtggt gggactttgt tctctgtgct tatttcccga gccattcagt cctgcattta
     1081 tattatttgg tacactgaac ctgttccaga caactgttgg agcatggttg ctatggcgat
     1141 caggaaattt aatgaaaata ggtgagtaac aattgaatcc aattatattg aaacgttctg
     1201 tccatcatat tccagtgtta gaagttgttc tgaaagaatt aagagaggaa cgtattcccg
     1261 ttgtcatcta ttatcacgga tggcagacaa gtaaggagtt agttttgacg caaggaagaa
     1321 aaattgcgca gcagggcatt cgtgtgatcc tgccagatgc gatgaatcat ggggagcgca
     1381 aacagccggt ttcttctatt ccatcctata cattttggga tagtatctac ggaaatctgt
     1441 ttgaatttga cacacttatc aagcatttag aaaaaagagg tcttctacat gatcagcttg
     1501 cagttggcgg ggtttcgatg gggggaatga caacatgcgc cttgttggct aaacatcctc
     1561 atatagtagc gggcgtgtgt ttgatgggtt cccctgcacc tttggaatat ggaaaagaaa
     1621 tcgtaaggcg cgcatcggaa tataattatg tcgtaccaaa agactatttt gatttgattt
     1681 catgggttaa gagctatgat ttgtcattgc agccggaaaa gttagctgga cgtcctctgt
     1741 tcttttggca tggacaagct gacgaaaaaa tcccttatat acaaacggaa cgatttgtag
     1801 aaaaaaatcg gcataagtct tacggaaaag aaattgtttt tcgttcctca aaaacacagc
     1861 gacatatggt acaaatacaa ctaatggaag aagcttccac ttttttagca aaaaatttga
     1921 taaaaaagta taaataattg aaacggaaaa tcactcatga cgatagagga ttttccgttt
     1981 tttattttgg gctataataa actctgttag gaaaatttgg tataattgat agtaagaatg
     2041 acaacatgtt agaaaggaag agagcatgcc cactttagca gatgttgcaa aacgtgccaa
     2101 tgtttcaaaa atgacggtct ctcgagtcat caatcatccg gaacaggtga ctgacgaatt
     2161 gaaagagtta gttttctcag caatggctga actggattac cgtccaaata ttgctgcaaa
     2221 agcacttgtc acgaatcggt cgcagatcat caaattattt atactggaag aaatcgacac
     2281 aactgagccc tattacatga atttgctgat gggaatcgct aaacggatcg gtaaagcgca
     2341 ttattctctc caattagtta caaatgatgc cttcgacgtc ggttcttgtg atggatacat
     2401 catcacaggt gtcagaaaaa aagacttcga ttggatcgac cgtttggaaa aaccagttgt
     2461 cttgtttggg gaaaattctg aaggatatga ttatgtagac agcgataatg aatatggtac
     2521 agcaaaagca acgcaatatg ccttagaaag agattatcaa acgattattt atatcggtat
     2581 cgaagtggac gagccttttg aaatttcaag ggaaactggt tatttatctg tgatgaagga
     2641 agttgatctt cctagtaaaa tcttgcggtt tccaaatcat tcgacagaag tagaaagata
     2701 tatgacagaa aactgggcag attttacaga taaaacttgt tttgtatgta gttcagatcg
     2761 gctagcacta ggagcagtaa gagggattat aaatgctgga ggacacttgc ccgaagaatt
     2821 tggtgtgatt ggatttgatg gggtattttt agaccaaatc agttcaccta aattgacaac
     2881 gatcaagcaa gatattatac gtatgggtga agtatgtgga gaaatgttgt taaaaaaaat
     2941 agaagaaaaa ggggcgagtc aaggttatcg tcgttttttt cctgaactag ttatcagaga
     3001 gacaacgaat taagtcttat tactatatat atatttatga aattcatcgc tattttctta
     3061 aaataatcag cgcattgcta ctgaaaacaa tgaatctgtg ctattattga gaaaagttcc
     3121 atttttgaga aggatggttt gaatgaaaga aatcagacga aaacatttcc gttttcctgc
     3181 gtacgatgat gagttaggcg taaaattaac caacgacaag aagcgagtat tatttgacgg
     3241 acaagaagat cttttgactg aacagaatca gtccccgttt gaacagatga aagaatttca
     3301 tttcacgaac acgaacaccg agaaaatccg tcgcaagcgt cgtgcaacaa atggattgaa
     3361 gtcagctccg cgtaaggaaa atttggaaaa gcataaagga aaattaccgg attataccgg
     3421 ccattaccaa tcagaaatca catcgacagg acgaaaaaaa ctttttggtg attcctctcg
     3481 ttctgtcaga caaagtgaaa caaggacaga gtccaagcat actacacgaa acgcatctgt
     3541 tgacacgaag gtgcgggagc gttcttattt tgttcctaaa tatgtacccg catcgattat
     3601 cccagaccct agagaaagca aaatttctga ggatcattta atcgaatcga tgaaaaaaac
     3661 ggatgactct tatctgttgt tcgatacaga accgacgccg tatcaagaaa aaagaaatgg
     3721 tgagccgtct gtacgaacat tcaatcgaac aaaaacgtta gaggaaacaa agcagtcaga
     3781 agaaaaaaaa tcgaaaaaaa gccatggtat cttagaacgc tcattacaag gattgatcga
     3841 tgatcaagga aactctttgg gagaaaatag ctattttaaa taagtgatat acaaatttat
     3901 attcggctac agttggaaag gaaacgctgc ggcgtttcct tattttatac tctatccgaa
     3961 agtttatatc gtatcctcaa atttttttga gtttaagcga attttttctc ccaataagta
     4021 agaaaataat ggcaaaataa aaaaacaaac tattttcgca gatcgtttgc aaaaatagtt
     4081 tattttttta taaagaagat tttactgaat aatatcattt tagtttacat aatgatattt
     4141 ctgtaaatta aataaagtag tgaaaaataa gaatcagtgc tctaactgtt caagaggatc
     4201 aagtggttca aatgtttctg tagtctgttt tgcttccaat tggggcaaaa cagatccaat
     4261 ttccagatac ttcactttat tcaatgtata agatagaata gaacagctaa gtaatgtata
     4321 cagaaaatgt gtgagatcca aataaagcaa ggagacaact aaaataccaa aagtaatcaa
     4381 gaaaagactt ttgccaatct taatatgaaa atatttttca atggcttgat aaatgatatc
     4441 tgttccgcct gtgcttccgc cgaatcgaaa gacgagaccg caaccaatgc cagaaagaat
     4501 acctgtcatc aaactattga tcagtagact atctacagca aaatgtatat gaaggctctc
     4561 ccataaatgt aaaaagaaaa ctagcgcaaa tgttccgacg atcgtccgga gaaaagcgtg
     4621 ttttccaaaa agaaacaatg agataagcaa taaaggtaaa ttaaaaagca gtgaagtgac
     4681 agaaggagcg aatccaaaaa gattatgcaa aagcaaagca ataccagtaa ccccaccatc
     4741 tgccagctta gatggaatat tgattcctgt cacagctaat ccgtagattc ctgcgcctaa
     4801 aatgattccg cacaattctg taaataaatt taattttttc atttctagcc tcttttcttt
     4861 tgaaaatttt cagcaacttc tttattatac tgacttatac tcttacttca agaggaaaat
     4921 gaaaaaaaat tatttttggc tgtttctttt tatttatcaa ataaggagtg gaaaaatgcg
     4981 agcagcagac ttattgacaa ttcttacaaa atcacccaaa aaaacagagt atcaaggagt
     5041 ttttttggct caagaacaaa aactggtgcc tgtgacaatg gtccagataa ataaagcaaa
     5101 tcaatttatc tttttatttg aacacggcaa agcaccactt gctatgaaag acatctttct
     5161 ttttttgatg aagaaccgtg agaaagctgt ttattatcag tcaaaagaag aactcattcc
     5221 tctttatgga gtgaaagaga tagaaaataa agtggtgata taagtaaaaa taagaaaaca
     5281 agacgtttat gatgtcaaaa caaccatttt ttacattttt ggcaaaaaag tgtcatgata
     5341 cagtataata ttcgttgaac aggccaataa aggtgttctc ccccacgaga tttctacttt
     5401 attggctgtt tctttttatt aaaataaaag ttgtgtgtgt aaaaaagata tagctgattc
     5461 caagtgacaa tttcgtatag atttttatgg tattcgtagt gaaaaaacga gaaccaaaaa
     5521 gttgatccga ctttgttgct tggattcttt ttttgtcagc atatttagag gtattttttt
     5581 cttttttttg ttcgtgctgt aaggttaagg caagacaagt tagttgggaa aaaggaaaga
     5641 aatgtttata cttaaagaat aacagaaagg aaggtcgcat gaataatttt atacaaacat
     5701 taagtgaaag aaaaggcgag ttgctggaag ctgcatttca acatctgtcc atttctctca
     5761 tttctttgct gattgcagca ctgattgcta ttcctttagc gatttgggca gccaatcata
     5821 aaaaaatggc agaagtctta ttgcagatca cgggtgtgct ccaaacgatt ccttcacttg
     5881 ccttattagg tttacttatc ccatttgtag ggatcggaac tgttccagca ttgattgcac
     5941 ttgttattta cgctttgctt ccgattttcc aaaacacgta tattggtcta gctgaaattg
     6001 acccgtctat tgaagaagca gcggtagcat ttggtatgtc cagaatgaga cgcttgctga
     6061 aagtagagct tcccatcgca ttacctgtca ttatctcagg tatccgaact gccttagttt
     6121 taatcatcgg tacggctact ttggcagcat tgatcggagc aggtggatta gggacattta
     6181 ttttgttagg tattgaccga aatacacctg ttttgacatt gattggtgcg atcagttctg
     6241 ccttgcttgc aattatattc agcggactga ttcgctggtt gcagcataag aaacctcgat
     6301 attccatcat tactttagca gcagtggtgt gtttatttgg cggcgtttct ttatatcagt
     6361 ctgccttgtt taaaaatgaa accatcacga ttgctggaaa attaggagcg gaacctgaaa
     6421 tcctgatcca aatgtataaa gaattgattg aagacaacac aaaaacagaa gttgaattaa
     6481 aaccgaattt tggcaagacg agttttttgt tcaatgcact ggatcaaggt caaatcgata
     6541 tctatcctga gttcacaggt actgtcctag aaagcttggt gaaggtacct gaagcaatga
     6601 aaagtgctga tttgacaaaa gaaaaaacat atgacgaagc agaagaatta ttgaataagc
     6661 aattcgatat gacattatta aaaccaatgg cttaccaaaa tacgtatgcc ttggcagtca
     6721 agagatcttt tgcgaacgaa catcaactta aaaagatttc cgatttggca gctatctctg
     6781 atcagatcaa agcgggattc acactggaat ttattgatcg ttcagatgga tataaaggaa
     6841 tccaagaagc atatggcttg aatttttcaa gtgtacaaag catggagcca agtttgcgtt
     6901 accaagcaat caataatgga gatgtcaata ttgtggatgc ctattccaca gatagccagc
     6961 tcaaggagta cgatctagtg actctagaag atgatcgagg gttattccca gcttatcaag
     7021 gcgcaccgct gatgaaaaaa gattttgcta aagaacatcc tgaaatcgtt aaagcactga
     7081 ataaattaag cggaaaaata acagaggatc aaatgattga tatgaattac caagtcaatg
     7141 tcgaaaagaa aaagccgaca gaagtagcac gaatcttcct gaaaaatgaa ggattagtaa
     7201 aggaggaaga tcagtgacta aattaatcga gttcaaacat gtgcaaaaaa agtatgatgg
     7261 aaagtatgtc atcgatgacc taaatctggc aatcaaaaaa ggagaaatct ttgttttggt
     7321 tggtccttcc ggtagtggaa aaacaactac tttgaaaatg atcaatggat tatctaaacc
     7381 atcagcagga gacatctact tcaaaggaaa atcgttaaat gaatataatc tgcagaaaat
     7441 gcggtggaat atgggatatg tgctgcagca aatcgctttg ttcccgacca tgacagtcaa
     7501 gcaaaatatt gaagtcatcc ctgaaatgtt aggttgggaa aagcagaaaa gagcagaccg
     7561 tgtagatgaa cttcttcaaa aagttggctt atctcctgat atttatcgag atcgtatgcc
     7621 tagagagttg tctggaggag aacagcaacg gatcgggatc atccgagcta ttgctgcaag
     7681 cccagatgtg attttgatgg acgagccatt tagcgcatta gatccgattt caagaaactc
     7741 attacaagaa ttggttttgt ccttacacga agaattgggc acgaccatcg ttttcgttac
     7801 gcacaatatg gaagaagcaa tcaagctagg tgatcgtatt gcatttatga aggatggaga
     7861 aattatccaa tgtgacacac cagagcagtt attgatgaat cctaaaaacg actacgttcg
     7921 gcatttcttt gatgaaccga aacagacgaa agagtggcga gtagaagatt tagtcgtcaa
     7981 tggatatttc ttaaatgaaa taccagaaaa tgctcgtcaa caagtttgct ttgatacgcc
     8041 tatgaaagaa gtatattcgc ttctttcggt gtatccaagc attgtgatag tagaaaagca
     8101 aagaagtatt gggtcgctga caagtaaaga aatctttgct tttttaagtc gagaggagga
     8161 aggaaatgaa aacatatgat gcaatcatca tcggttcagg tgtgagcggc ttaagtgctg
     8221 cttatggatt gaaagaagca ggtaaaacag tactagtggt cgaagaagat ctatggggcg
     8281 ggacttgtcc taaccgtgga tgtgatccta aaaaagtctt gttaagtgca gtagaggcac
     8341 gtaatcgggt aaaacaattg agtggaaaag gttttaacga gatcccaact gccaactggg
     8401 aagaacttca aaaattcaaa cgaacattta cggatccagt cccagaaagc cgaaaaaaac
     8461 aattagcaga agctgaaatc gatcatcttt caggaaccgc tcgttttttg gatgattcat
     8521 ctattgaagt caacgaagaa gtcttccatg cggattactt agttttggca accgggcaaa
     8581 gacctacgat cttaccagtg gagggaaagg aatacttgaa aactagtgca gactttttat
     8641 cattgcctgt actgcctaaa gaaatcattt ttatcggtgg tggttatatt gcttttgagc
     8701 tagctacgat tgccaatgct gcagggagca aagtaaccat tgtccatcat aatcaacggc
     8761 cattaaaaga atttgaggcg tctttggtag aggaagccgt ccatcaaatg gaagcatctg
     8821 gcattcagtt tgcttttggt gttgaaaccc aaaagatcat ttcagaaggt actcgctatc
     8881 gtttagtcgg aaaagagacg gaattagtag cagatatgat tttttgtgcg actgggagac
     8941 agccgaatac agaatcttta gcacttgagc aagcgaatat cgtctttgat aaacacggaa
     9001 ttgcagtcaa tgattatctg caaacgagca atccaaaaat ttttgcgtgt ggagatattg
     9061 tttcaaggaa aaccccaaaa ttgacaccag tcgccacttt tgaaggaaat tatgtagcta
     9121 agcggataac ggatgcaaca agcgaaccta tcaaatatcc gattatacct acgatcgtct
     9181 acgccagtcc taaacttgct gaagtaggag ttacaaaaag tcacgcctct tcgtcagatc
     9241 aagtggtaga gatggatctt accagttggt tcacctatca tcgtgtcaat gaaccagttg
     9301 ctaaggctga attgaccttt gaccagcaaa attatttgat tggtgctgca gtgattagcg
     9361 agcaagcaga cgaattgatc gatgatttga cactcgtcat caatcaaaaa ttgactaaaa
     9421 aagagttgga tagctatatc atggggtatc cgacattggc aagtgatctc tcctatttat
     9481 tgaaataatc agcatgataa ctaaagcgct tgttgctttt tccttcttgt gctacacttt
     9541 aaaaaatgaa tacctgtttc tggggatgtc gtagacgaca tgagagtaag ttgtgaactt
     9601 agacccattg aacctgtcag ttaatactgg tgaagggaga aacatagcag acgcttgaag
     9661 cgggttacta tgtcgtgccc atttcaagcg ttttttgtta ttcatattag aagaaaggag
     9721 gtaacaaaat gaagaaaaat ctttatccag cagtcagtat ggcattcatt ttaattattt
     9781 ggcagattgt tgtcatagtt tggaaaatac ctgcctttat tttacccgga cctgctgctg
     9841 tattttctgc attagcggca gatgcacaag tattactttc ccattctgtc acgacattaa
     9901 atgaagcagt gcttggtttg gtaatagcta gcgttctttc ttttattact gccttggcaa
     9961 tggattattg gaagttttta gaaatgtctt tttatccgtt actagtgatt tcacaaatgt
    10021 tgccaatcat ggtgttaggg ccattactta ccctatggtt tggtttcggt atgcttccaa
    10081 aagtgatcct tgttgtcttg ataagctatt ttccgatcgt agtttctttt tcggatacat
    10141 tgaggaaagt atcaaaagag caaatcatct ttttgaaaac gatgggggca gatacaggga
    10201 agatttatcg aatatataaa ataccagcgg gtttatccgg cttcttttcc ggtttaaaag
    10261 tggctgctac ttattgtgtc agcggagcag tcgttggaga atggctaagc gctcaagcag
    10321 gcttagggta ttacatgata cgcgtaaaaa acagctacca gatcgataaa gtttttgctg
    10381 cgatcatttg tgtcattcta ttgagtttat tgctgaatgg cgcttgttca ttattgaaaa
    10441 aagggtatta tcgtatgctt tatatttttt aagagaaggg gatcaaatga aaaaattatg
    10501 gcttttatta ccgctactgt tgcttttatc cgcttgtggc actgcaaaag aaacaagtag
    10561 caaacaagaa ataaaggatt tgaaaaaagt gacacttgtt ttggattatg taccgaatac
    10621 taatcatact ggcatctacc tagcaaaaga aaaaggctat tataaagagg ctggtttaaa
    10681 tgtccaaatc atcgaaccag gagataattc gacaagtatt ggtctagtag gtgcggacaa
    10741 agcacaattt ggtgtaagtt atcaagaaga tgtcacttat gctcacgcag atggacagaa
    10801 tataccagtc aaagcaattg ctacagtgat caaacataat acttctggat tcgccaccct
    10861 atcagacagt aacatccatt caccaaaaga ttttgaagga aaaacatatg caggttggca
    10921 aagtccaagt gaagaagctg tcttaaaagc tgtgatggaa aaagacggcg gggacttttc
    10981 aaaactgaca atggtaggaa gcaatggaga agggccagaa agcttaggaa aatcctcaga
    11041 tatccaatgg tactttgaag gttgggatat gatcaaagca aaagaagcgg gtattgaact
    11101 aaactatatc ccattgaaag aattagatga acggttagat tactatactc cggtaattat
    11161 tacgaatgat caactgatca aaagtgatcc agaattggta cagtctttta tggatgccac
    11221 gaaaaaaggc tatcaggaag ctattaagga tccaaatgac agtgctaaac tgttgcaaaa
    11281 atatgcaaaa gaaaatgatc ggacgttttt agaagaatca caagcattct tgtcaaaaaa
    11341 ttatacggat gatcctgaga attggggatt gatggaagaa aaagtttggc gcaattatac
    11401 agcttttatg caggaaaacg gattgatcaa gcaagatgta ccttcgcaag aactattcac
    11461 taatcagttt ataaaatagg agtgatagat atgtcaatcc aaatcagcca cttgaatgta
    11521 gtcattgaaa acctgaaaat attagaagac atccatttca ctatccctaa agataccttt
    11581 acatcgattg tcgcgccaag cggagccggt aagtcaacat tgctgaaaac tttaacagga
    11641 gtccagccta tgacttctgg aacgatcaaa gtagacgatc aaaaagtaac tggtctccat
    11701 acagcattta gttatatgcc gcaagaagat atgttacttc cttggctgag cgtctatcaa
    11761 aacgttacgt tatatcaaaa aatcaatcat ctaacaatca atgaagaaca agtaagggat
    11821 tatctggata tctttgggtt aaacggctat gaacattttt tgccggaaca attatctggc
    11881 gggatgaagc agcgaacggc cttgttacga acaatcatga atccttcttc ttacttgctt
    11941 cttgatgaac catttggagc gttagatgct atgaccagag ggcagatgca agactggatg
    12001 ttgaagctgc ctaaaaaagc aaagcggact actttacttg tgacgcatga tatcgaagaa
    12061 gcaatttatt tatcagacag gattcttgtg ctttccgccc gtccggcaca tgtgattgct
    12121 gagattcaag tgcctgaaaa acgacggtca cgtgaatggc tactgcagca atcagagttg
    12181 aagcaaacga tttatcagtt attggcaggt gaattagatg ttaagtgatg ctcattgtca
    12241 tttagatggg agtcagagtt tagcactcct tcagcaggaa cacacgattt tgacgatcat
    12301 caattgtgat tcgccagaag aatggaagga aaacagacag cttgcagcaa gtaagactca
    12361 agccttaagt tacggtatcc atccttggaa agcagatagc tatacgtttg aacaagttga
    12421 gccttttttg aaaaaagcaa ggatcatcgg tgaaataggg ttagataata tttggacgaa
    12481 tgtaccgatg actacacaaa aaaaagtatt tgagcgacag cttgcttttg cagccataaa
    12541 tgagaaacct gttgtactgc acacaaaagg atgcgaaaaa gagatcttaa attatatcca
    12601 agcttaccct aatcactatt tgatccattg gtattcttct ttggactatc aacaagacta
    12661 tattgattta ggctgttatt tcagcattgg tcttgatttg aaaaagaatc cagcagtctg
    12721 gcaactagct aaagcagtcc caatcgacca cttacttatt gaaacggatg gactacatgc
    12781 agcagagtgg gctttagggg ggattttttc agaaaaagat tatgtctcac tgcttgaaga
    12841 acagttaaag acaatcgctg agatcaaaga gctatcagtt gaagaagtta aaaaaaatac
    12901 ttatcaaaac ttggaacgtt tcattagatt aggtaaataa aaaagagatg tgacacaact
    12961 agtgtcgcac ctctttttgg ctttctttgt ataaaagtaa actgtttgat taataaatga
    13021 atcttagtac caaccgtttg cttcccagaa tgctttcgcc gcttcccaag aaccataacg
    13081 tgaagtaaca tattgttctg ctactctttc ttggtttgca gcagagtagt caccatttaa
    13141 gtaagaagaa tctaattggt aacgtccgat gtaacgtccg ttcgttgctg tgtaagaacc
    13201 gcttgattct ttttgtgcga tccattcttt tgcagagctt gtgcttgctg gagtagcagc
    13261 agtttctgtt acagcaggag caggttgtgt ttcagcaaca ggcgctgctt gtttttccgt
    13321 ttgaaccgtt tcttgtacaa caggttgttc agcttggact ggtgcttctt gaacggctgc
    13381 ttgaggttca gcagctgctt gtgcagagcc ttctgttggg attgttaatt gttgtcctga
    13441 gta
//
LOCUS       DADVXE010000073        12736 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.074, whole genome shotgun sequence.
ACCESSION   DADVXE010000073 DADVXE010000000
VERSION     DADVXE010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12736
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.074"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="KB913_002329"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="KB913_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBB6820663.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="KB913_002330"
     CDS             complement(322..891)
                     /locus_tag="KB913_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBB6820664.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="KB913_002331"
     CDS             1077..1979
                     /locus_tag="KB913_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6820665.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="KB913_002332"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="KB913_002332"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBB6820666.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="KB913_002333"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="KB913_002333"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBB6820667.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="KB913_002334"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="KB913_002334"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBB6820668.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="KB913_002335"
     CDS             8547..8732
                     /locus_tag="KB913_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBB6820669.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="KB913_002336"
     CDS             complement(8794..9990)
                     /locus_tag="KB913_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6820670.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="KB913_002337"
     CDS             complement(10160..11596)
                     /locus_tag="KB913_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBB6820671.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="KB913_002338"
     CDS             11889..12698
                     /locus_tag="KB913_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6820672.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3803 a         2673 c         2250 g         4010 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt gacaat
//
LOCUS       DADVXE010000074        12607 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.076, whole genome shotgun sequence.
ACCESSION   DADVXE010000074 DADVXE010000000
VERSION     DADVXE010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.076"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="KB913_002339"
     CDS             complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="KB913_002339"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBB6820673.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="KB913_002340"
     CDS             complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="KB913_002340"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBB6820674.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(2298..2960)
                     /locus_tag="KB913_002341"
     CDS             complement(2298..2960)
                     /locus_tag="KB913_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6820675.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            3144..4790
                     /locus_tag="KB913_002342"
     CDS             3144..4790
                     /locus_tag="KB913_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBB6820676.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            4781..5863
                     /gene="uxuA"
                     /locus_tag="KB913_002343"
     CDS             4781..5863
                     /gene="uxuA"
                     /locus_tag="KB913_002343"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6820677.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(5971..7524)
                     /locus_tag="KB913_002344"
                     /pseudo
     CDS             complement(5971..7524)
                     /locus_tag="KB913_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            7672..8813
                     /locus_tag="KB913_002345"
                     /pseudo
     CDS             7672..8813
                     /locus_tag="KB913_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(8939..10018)
                     /locus_tag="KB913_002346"
     CDS             complement(8939..10018)
                     /locus_tag="KB913_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6820678.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(10121..10561)
                     /locus_tag="KB913_002347"
     CDS             complement(10121..10561)
                     /locus_tag="KB913_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6820679.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(10618..11028)
                     /locus_tag="KB913_002348"
     CDS             complement(10618..11028)
                     /locus_tag="KB913_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBB6820680.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(11208..11642)
                     /locus_tag="KB913_002349"
     CDS             complement(11208..11642)
                     /locus_tag="KB913_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6820681.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(11742..12590)
                     /locus_tag="KB913_002350"
     CDS             complement(11742..12590)
                     /locus_tag="KB913_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6820682.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
BASE COUNT         4212 a         2347 c         2243 g         3805 t
ORIGIN      
        1 tcttgtcacc atcctttttt ccgctctctg actttttaca atcttcatag ctcaagtgcg
       61 catcagataa tcgaatgctc ctaaagctgc agtagctcct gaacccattg aaacaatgat
      121 ttgtttgtat ggactatctg tacaatcacc agctgcgaaa acgccgggga tattcgttgc
      181 gccatttttc tcggtcacta tttcatttct tggattcatt tcgatcgttc catctagcca
      241 atccgtatta gggagtaagc cgactagaat gaatactcct gaaacagcta gtgtatgcat
      301 ctccatcgta cggcgatcga tataggagag agattctacc tgattcgtac cgctgatttc
      361 tttcgtcgct gcatgtttga taacagtgac attcgcaaga gagactagtt tatcctgtaa
      421 gatttgatct gcttttaatt ctggtaagaa ttctagaaca tatacatgtt ttgctaaccc
      481 agccaaatcg attgctgctt caacaccaga attaccacca ccgataacag caatctcttt
      541 tcctttaaat aaagggccgt cacagtgtgg gcaataagca attcctttat ttttaaactc
      601 tttttcgcct ggtacattga tagaacgcca gtgcgcacct gtcgcgatga tggcggtttt
      661 tgctttaagt gatataccgt tagctaagcc aatattaata aaatgttgct ctttatttaa
      721 ggaaacggcc tgttgattca tcataatgtc gatagggtaa ctacgcacat gactttctac
      781 ttgctgcatc aattttggac cttctgtgta agaggtacca atcatatttt caatccctag
      841 tgtttcaacg acttgtccgc cgaaagaatc agcgacaagt cctgtacgga ttcctttacg
      901 tgctgcatag atagctgcac tactagctgc tggtccaccg ccaatcacta atacatcata
      961 aggttctttt tcaaacaact cttcttcaat caaagggcca gtgatttttt caacaatttg
     1021 ttcgatcgtc atgcgtccgc tactaaattc ttctccattt aaaaacacag ttggcactgc
     1081 catgattttt ttatcatcga tttctttttg gaacatccca ccttcaatca tcgtatgagt
     1141 aatatttgga tttaatacag ctaatatatt caatgcctgt acaacgtcgg ggcaattatg
     1201 acaagtcaag ctaacataac tgtcaaaatg caatgtttgt gttatttttt tgattttaag
     1261 actcaaagat tcactgattt tcggtgcccg tccactaatt tgtaacatag ccagtaaaaa
     1321 agaggaaaat tcatgaccga gggggatacc agcaaaaacg attccacttt ctttgccaac
     1381 tggattgata gaaaaactag gtgtgcgcat cgaatctctt ttttcccaag agattttagg
     1441 agacatttct gctatttcct tcgtaaattc agctagtttt tgactatttt cactattatc
     1501 caaactaaca gaaaaaacaa taggagattc aatcagtgct aaatattgtt cgagattttg
     1561 tttagtttct ttgtctaaca tatccaccac ctaaatcttt ccaacaagat caaaacttgg
     1621 tttcaatgtt tcgccacttt ctttccattt tgccggacaa acttcacctg ggtgggtacg
     1681 tacatattga gcagcgcgaa tcttatcaat cagtgcacta gcgtcacgac cgattccatc
     1741 tgcattgatt tccatagctt gaacgattcc gtctggatca ataataaatg ttcctcgctg
     1801 agctaatcct tgctcttcat ccaaaacatc aaaaatacga gaaatctgat gagacggatc
     1861 accgatcatc acgtattcga ttttaccgat agcatctgat gtatcatgcc atgctttgtg
     1921 agtaaagtgg gtatcggtag agcaagaaaa gacttcaaca cctaaagatt tcaatgtact
     1981 gtattgttct tgtaagtctt ctaattcagt aggacaaaca aaagtaaaat cagctggata
     2041 gaagcaaaga atactccagt tccccataag atctttttca ctgacttcta aaaattctcc
     2101 ttgatgataa gcatgtgcat taaattcttc gatttttttc ccaatcaatg acatagtaaa
     2161 acctccaata ataattattt atttataatt attgtaattt agttggagtt gcaaagtcaa
     2221 tggatatttt gttatttaat aaagattact caaaaacgaa ggttaattat aaaaatagaa
     2281 gaggtcgcaa gaaaatgcta ctgctggaaa tactcgggat aacgttgagt aacagtttcc
     2341 tgttctttca gcatcatgtg taagtgcaat cccgtttgaa atcgagcttc ttctggtttt
     2401 ttatcaacta aagccttgag taaatcataa tgttgttcca tgatcgtttc ccatggaagc
     2461 ccctgaatgg tcactcgtaa ccagcggaaa cgttctaaat gggtattatg gtcatctaac
     2521 cagttccaaa cttcttttct tcctgcaatt tcgaaacaag cttcatgaaa taaattatct
     2581 gcacggaaaa aagcgcgttc gtcatttatt ttgactgctt tttcttgttc ttctaaaatc
     2641 gtttctagca ctattcgtgt ttgtgtgtcc aatttggaac aacattcaat catgatttgc
     2701 tcttccaact gttctcggac aaagcgagca ttttctgcag aaacaagatt aattttggaa
     2761 acatacgtac cactttgagg tatcgtatac acgagttctt gctgacgtag ttgaatcaat
     2821 gcttcgcgaa tgggagtccg gccgatagca agatgttcct ccagtgcctt ttcagatatt
     2881 ttccttccag gttctaagtc agcatagata atttgtttac gaatcgcttg ataagcttgt
     2941 gattgcaagc tgcttttcat ctttattcct ccaaaatcat ttctatgaac gtagtataac
     3001 agaagaggtc tgaaaaacaa tctggtatgt cacattaact agtaaatttg tataaatagt
     3061 aaaattttgg ttgacatagc gatttttatt gcataaaatt cacttgaata caaaaactaa
     3121 tatgttagtt taggagggga aaaatgattg atttaaacaa ctggaggaac tttatccctg
     3181 aattatctca aaaagaagta gaaatacctc attttgaccg tgcatcatta agagaaaatg
     3241 gacaaaaaaa tcctgtctgg atccatttcg gtggcggaaa tctttatcga ggatttcatg
     3301 cagaaatcgc tcaacgttta gcggatctag gcgaattgtc cactggtgtc attgtttgtg
     3361 aaacattcga tgaagaaata attgaaaggg cttaccaaga ttttgatgat ttgattcttg
     3421 aagtggtcat gccaagcagt ggagagttcg tcaaacgtat attagctgcg acagctgaca
     3481 gtctgtattg tcatccagat tgttctgaac actttgataa gatgattcga cactttgaaa
     3541 atcctagttt acaattagtt acttttgcta ttactgaaaa aggttatcga ttgaaagata
     3601 caaataataa atatatagga ccgattgcag tcgatataaa aaatggtcca aagaagccat
     3661 cacatacaat gagtattctt gctgtgctac tttataaacg ttttttatct ggagcttggc
     3721 cgattgcact tgtctctaca gataattttt cacaaaacgg tagtcaatta cgtacttctt
     3781 tgctaacgat cgcaaaagaa tggcaaaagg aaggttatgt acaaaataca tttatccaat
     3841 acttatcgaa tgaagaaatt gttgcgtttc catggacgat gattgatcgt atcaccccga
     3901 atccttcctt gtcagttagc aaaatgttgg caaaagaggg cttttcaaat atgtcgattt
     3961 tccaaaccgc aaaaggaaat aatattgctc catttgtcaa tacagaggac atccattatt
     4021 taatcatgga agatcatttt cccaatggac gtccgaaatt cgaaaaagct ggggtattct
     4081 tgactgatcg tgcaacggta gataaagcag atacgatgaa ggtgacgact tgccttaatc
     4141 ctttgcatac gtctttagct attatgggtt gtttactggg gtataggagc atagctgagg
     4201 agatgaaaga tccagattta tcgctgctag tttctgaaat cgggtacaat gaaggcctcc
     4261 cagttgtgga gtctccaggt atcattgatc caaagatctt tctggaagaa gtaattactg
     4321 tgcgcttttc taatccaaat attcctaata tgcctcagcg aatcgccacg gatacctctc
     4381 aaaaggtggc gattcgttat ggtgagacga ttaaaaaata tatggaaata gaagttaaag
     4441 acccgcagac acttgtattc ataccattga ctctcgctgc ttggcttcga taccttattg
     4501 gcattgatga tcaaggaaaa ccattcatcc cgagtccaga cccactattg acagaccttc
     4561 agcataagct ttccgatatt caactgggta cgcaagatac atcacatatt catgagaaaa
     4621 tggctcctat tttgtcaaat aaagaaattt ttggtgtaga tctttaccaa gcagagcttg
     4681 gcagaaaaat agaagaaatg ttcatcaaga tggtagcagg accaaatgcc gtacgaaaaa
     4741 cattacagga ttacttacaa gaacatggag gaaatttatc atggaaatga cttttagatg
     4801 gtacggatca caggaagaaa agattacctt agatgaaatc agacagattc ctgcggtcaa
     4861 agggattgta ggcacattga tggatatacc agtaggagag gtatggccta gggagaggat
     4921 caaagaacta aaagaagaaa ttgagtctcg tgggttaaca ctaaaagtaa ttgaaagcgt
     4981 caatgtgcat gatgccatta aaattggatt accttcccgt gagcagtata tcgaaaacta
     5041 taagcagaca atccgaaact tggcagaata tggaatagaa gtcatctgct ataattttat
     5101 gcctgtattt gactgggtga aatctgacct tgactaccgc ttagaagacg gctcatccac
     5161 gttagctttt atatctgatg atattccaga tgatccaaga gaaatcgtcg cgcgcatcga
     5221 acattccagc aatgaatttg gattgccggg atgggaacct gagcgcttag ctcctatcaa
     5281 atccttgctt gaagcctatg catcagtaga cgaagaaaaa cttcgagaaa attttgccta
     5341 ttttctccaa tcaatcatcc caacatgtga agaggtaggg gtcaaaatgg ctgtacatcc
     5401 agatgatccg ccatactcga tttttggatt agctcgaatc gtaaagaatc gagaagattt
     5461 agattggttg tgtcgcatag tagacagccc ttataacgga atcactcttt gtacagggag
     5521 tattgcagaa gatccagaaa atgatgtata tgggatttta gcagaatttt gccaaagaga
     5581 tcgaatccca tttgcacatg ttcgaaatat taaattttta gctaatcgag atttctatga
     5641 ggcaccacat aaatccgaat acggttcatt agacatgtac cgcatactaa aaacaatgta
     5701 tgacaacgga tttaacggat acatccgtcc tgatcatgga agaatgatct ggaatgagac
     5761 aggaagacca ggatacggct tatatgatcg agcattaggt gctgtttatc taaatggatt
     5821 atgggaagca atcgaaaaag gaaacaaaag taaagataat tagtgaaaaa aactgtaatt
     5881 ttattatgta aataagaagg atgttcaaat tcttgataca taaatccgga ggttgttaat
     5941 aagcattcgg atttatgtat cttatttggt ctaggaagta acttgatttt cttttttcga
     6001 ttgatccatg agtgcttctt cttttaattc aaagatatat tctgagatcc tcataatcac
     6061 ttttttccag tcttctggtg tgatgattcc ttttaaaata tagatttttt tgatatgaga
     6121 aggcaattgt ttcaaagggc agtcgctgat aacgatgttg cagttctcca taaaatcatt
     6181 ttgtattttg atcgattcat ttgaaaaaat ttgttctatc ttaacgatca gatctttact
     6241 gatataaaaa tcacgcgtat agttcacacc aatcacaatt cgcggctgtt ttttgtagcg
     6301 atcatacaaa tgtactaggt cttcaaccat ccattgcaca ttttcctttt ctaaaataac
     6361 tggtaacaag tgttgatttt gttctctgaa atccatataa aattgttcaa tggcggtttg
     6421 gacttctttc aatacgctat gttcttgata aagcatgaaa gtaggaaggg gcgtatttgg
     6481 ttgattgaag ttaagaaatc cattataaag tttatttcgt gcgaatgcca atgagtaaag
     6541 aatcttttct ttttcaggta taaacaaatc aaatacagta caaagggact ccaccatttc
     6601 tcttgaataa agaacatgag gaacgtttgc tttttttaaa agtttgtatt gctccaagct
     6661 tgtttcttcc gattcgattt tcgtgataga aagtcgagct aaaatattca ctaagatgcg
     6721 ttgttcgcga caaattggca gattaggtcg caaaatatct acagagagat caataaaaaa
     6781 gtcaatatat tcatactctg tgaattcttt ttgtacgtct ttcacagaag ttgcaggaaa
     6841 attctcttta catattttta atagaaaata taatttatct atcataccgc tatttagtcg
     6901 gtcaagtact tcttttttaa aaaaagtatt catcataaaa gccactactt gcggatcttc
     6961 atcataaaat tctgtagcag tacttgaaaa gatgttccaa taaatatcta atgctgcata
     7021 ttgaatttgt acctcttttc cagaaaaaga ctttctgcca ttattagaaa aggagataga
     7081 caaaccgtac tatgctaaaa atgcattaat ctttttcatt ttcgtataca aataagaggc
     7141 actatagttt gtttgctgac tgaaactgat aatcgaattt gtctgacagc tgaacaaaga
     7201 agtcaagatc tgataactga ctgattcgtt gcagtatctt ccaaatagac gataatagca
     7261 gtaagccgga tcaattcctt caaaattcaa ctttaaaaaa ggtttttgct tatcaatatg
     7321 cagttctgtt agattgagac gctcaaagtc ttgttctaat tctttgatgt atagtaaaaa
     7381 atttgattca gacatatgga aatgatctgc taaatattgt gtagtaataa agaaacgatg
     7441 ttcagatagg aaaagaaaaa tatctaattt tgtattgctt tttttcttca agataaacgt
     7501 tttaatcgct tcttgagttt gcatgaaaga ggctcctttt tacttaaatt gttaaaactt
     7561 gaaaatatta ctgttttttt cataaattta gacaaaaaaa cagtaaacat ataggtagaa
     7621 tctctactat cttatttctt gcatacaaaa aaatcaagga gtgagagagt tatgagatat
     7681 tcaaccatct taatatcaac atttgcagcc ttaagcttat cgcttactat aaatcagaca
     7741 gtccacacag aggagacaga aacagccaaa tggacagaaa ccaagtgggc caacgtcaat
     7801 cgaattacct ttcaggatga attttcatcc ttcaattcag gagtcgcaaa attaagaaaa
     7861 ggacaaacag cgaccatcaa agcaaaaatt gactattcgg gagacttagc acctatacta
     7921 caatcagctg ttacatttga gaatgttgat cccactttgt cgattggcta tgacgagaac
     7981 actttgacta tccaacacaa gcaagcgata tttaccttca ccgttacatt aaatcaggac
     8041 ttgttaaaac cagcgctttt tactgtcaag gtatcagatg gactaccgaa cgatcatcat
     8101 ttaacgccgt atagtcagcg gcagacaatt gagcaagatt cagccatcga ctcaggagga
     8161 gatcttgttg aagaaccaac agataaacca gaaaatgaaa ataagccaga agtaccgcct
     8221 acagaaaatc cagacggaga acagaaaccg gaaatagaac ctggagaaga acccgataca
     8281 gaaactcaac cagagccaga caataaatca aaacctgaaa taacccctgg agaaaaacca
     8341 gatgtaactc cagaaccaga tacggattct ggaaaccaaa cagtaccgga aacaaatcca
     8401 gacacagata atgaaactga aaatccagaa aaaccagagg tagatccaga agaaaaacca
     8461 gatgtgactc cagaaccaga tacggacgca agagaccaag gaataccaga aaaaataaac
     8521 aaaaaaacaa ttcaagagga tggaaaaaaa gagagtaaaa aatcaaatct agcaattcta
     8581 aaaataaatg aagagcagct gaataaaaaa tcacgaatat ttgatagcgc ccaatcagct
     8641 gaaaccttaa aaagtagcaa ggatacaacc tttgctgtcc tgaaacgaaa aataaacagc
     8701 taccaaaatc cggagagtca caaaacaaag ttatactgtg gagcggaatc attctattaa
     8761 gtatagcaac aatgctttct gcaaaaagat ttaaacaaaa cagatctctc taacatttga
     8821 ataatgtctg tgaacgcatt tttcaaataa aaagaaatat ccagaaaatg accccaaaat
     8881 accagattga aatctgatat ttggggtcgt tcatacttta tctttcttca tatttatttt
     8941 aagggatatc tgtttctttt ggaagatggt tcgggatctt tttcactttc aatacatcta
     9001 aaaagaaggt aaagatcgga atgccgacaa tcaagcccca aacgccaaag aaccgttcgc
     9061 taacaagtaa gaccacaaat gtataaaaaa tcggcagttc tgttttgctg gacatcaact
     9121 tcggattcag cacataagac tcaattagat ggacaatcaa aatcgtaatc aggatataaa
     9181 caacatctcg gatgcctcct tgggaataag ctatgaaaga tagaggaata caagaaatga
     9241 taacacctgc tactgggatc agacttaaaa tgaaaatcat gatcgctaaa ctcagcagct
     9301 gatgaaagcc aaatacagcc aaggcgattg tagtgagcaa cgtatttaaa agagcgacaa
     9361 caaattgagc ttctaatacc aaaccaaatg tattgacaaa cttatcggca aaatagtaaa
     9421 tatcttgaaa gaaccaagaa aattcacttt ttaaaaacaa tcttgagaat acaattgttt
     9481 ttttcttttc aatcataaaa aagaaactta agatgaatga catagcaaac gccactgcca
     9541 tttttcctat atcctgtaaa tagccaagcg caatcgaagc gccattttga agctgttcaa
     9601 aaaaatcgtt tcgctcaata taagtatgga tatattgtaa aacaggatct gcatcttttg
     9661 gctgatgctc gtaaaaatta ataacggact ggatcatgtc aaatgtttga tgaataagca
     9721 tcgggatata ctttgtgaat gccagataga taaggtaaac gatcagtgta taaatcatga
     9781 tagctaaaac acctgtaggg attcggacaa atcgctgaat gatttgaaca agatgaatca
     9841 tcaaataagt aaagataaat gtgagcaaaa tggttgtaat catacttcta actaagaaaa
     9901 gaacaaaaac gacaaataat aaaacagtga gacggcgtat tttttcattc gccaaaaaac
     9961 gctgataaac ggtcaaatcg acaacctcca aataacaaaa aataaacacg ttattcatta
    10021 tatgatggaa tatgaaaata agaaagagca aaaagaaaaa ccgctaaatg acgttatctt
    10081 atgagttggt tttcctcata aaatcgttca tctagcagtt tcagcccttt ttctggtctt
    10141 gatgaaaatt atctagcatt tttcgggtca gatgttgcag tgtatccaat tcttcctgtt
    10201 caagtggaag ataagacttg atcttttgtg gaataccttc tgcttgtttt tgcaacgcag
    10261 caccttgagc agtcagcgta acatttacga ttctttcatc acccgtttca cgctgacgat
    10321 taatataatt tttttctgct aactttttta gtaagggagt cagcgtacca gaatccagac
    10381 acaaatcatt tcctagctct ttcactgaag tctttttctt ttcccataaa actaacatca
    10441 caagatactg ggtataggta agattcagcg gcttgaggag gggagtgtag tgtctaatga
    10501 tttctttaga ggcggcatat aaaggaaaac atacttgatt aactaaatat agatcttcca
    10561 tttttccacc tccgctgttt tactatagtg tatcatagcg gatttacaca aaaaagtcta
    10621 ttcactaact gctttcagag taacttctat atttccagct gtagcttttg aatacggaca
    10681 cactttatgc gctgcctcta ataattcttg cgtttcttcc agagaaagac cttcgataga
    10741 tccttcaatc tctacaccta agacaaagct cgtttcactt tctgaataaa gggaaacttg
    10801 tgcactgaca gtagaagccc cagagatatt tttttgctgt ttgatcaatt ctaatgcact
    10861 gttaaaacat gcactgaaac cagctgcaaa caattgttca gggttggttg cattttcgac
    10921 gcgtttacca ggagctgcaa tattcaattc gaatgtacga tcgggattat gcacttctcc
    10981 agagcgtccg cctgtgttga tcattttcgt agaatacatt tttttcataa agttaccacc
    11041 tttaattata ttttatacaa ttgaatttta cacaatataa ttgtggaaag caaagaaatg
    11101 gattggcata agataaataa gagaaagcac atgaaacaga cgcgctttct cgaatagcaa
    11161 acatatacaa aaaatatcag agacaaaaaa taatctcatc ataaacatta catatatttc
    11221 tcaaaaagtt gttttctttc ttcaaaaatt acttcacgat ggacctgatg aagcatccat
    11281 aaataaccaa aaggatctct gaacattgag ttagtcacac caaagtccat catttctgtc
    11341 atttcttgaa tctctacaca gccatttcgt aatgctttat tatgtgtgtc ctcgatatca
    11401 gagacgatga tattgaacca gatcgtattt ggatgttcag cagtaggagc agtcaaacca
    11461 agagacgtgt tttcatccag catatggaat ctcgtaccat acaaggtaaa aatgacttca
    11521 ttattgcctc tagggtaatc tgttgcctca atcagttgta tttcatcaaa gattgtttga
    11581 tacagttcta gtgctttcaa actatcattt aatacaaaat cgatttccgt tcctttatgc
    11641 ataaagatct cctctccttt tcagtcgaac agttactaga ttcttttatt ataccagcta
    11701 aagaaaacgc attcaaaaaa atagcggatt tacttaccaa ctcattcgat tggatgataa
    11761 gtaaatccgc gtcccattac ttctgctacg ctgctgacaa tgacaaaggc acttggatcg
    11821 atttcttcta tcaatggttt cattcgggaa aattcatgat cagtcacaac gatcaataaa
    11881 acctcttttg actttcgatt atacccgcct tttgcctcta gcagggtaag gccacgtcca
    11941 atctcagcac ttaagcgaag gcggatgtct tccaaataat gttcactcat gaccataaca
    12001 gatttctttc gattgatacc tgtttcgata taagtcatga caattgaagt gattgcaata
    12061 gataaaatag cataaagaaa ctcttctatt ccaaaaataa acagattaag agaaacaacg
    12121 aatgcgtctg taaaaaataa gccaatcgaa gtattcaagt ggaaatattt tttaaaaatg
    12181 aggggaggga tcgtcgtacc gccgctagaa gagttgtttt tatataaaat cgcaactcct
    12241 aaagcaaaaa tcgcacttcc aaaaatgaca gacaacaacc gatctgaagt aatcattgtt
    12301 tctggaacta ttgcaatgat taaaggaaaa accaagcttc cgaaaagtac tttaaaaaag
    12361 ggttttttac ctaaaaatag aagagctagt accaacataa cgatattcaa cactaaaata
    12421 actatagctc ggtcaaagcc taaagcagct tccagtaata ttcctagacc gctgacacct
    12481 ccagcagcaa tatgatgagg ccctaaaaac atattgatag cgactcctaa tatgaagagg
    12541 gcaaaaataa tcttaatgta tgtccatata aattgtctcg tttctttcat ttattcactt
    12601 ccttaat
//
LOCUS       DADVXE010000075        12352 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.077, whole genome shotgun sequence.
ACCESSION   DADVXE010000075 DADVXE010000000
VERSION     DADVXE010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.077"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(130..777)
                     /locus_tag="KB913_002351"
     CDS             complement(130..777)
                     /locus_tag="KB913_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBB6820683.1"
                     /translation="MEQTIKPYQYFFIKREVDQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(1056..1559)
                     /locus_tag="KB913_002352"
     CDS             complement(1056..1559)
                     /locus_tag="KB913_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6820684.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1682..2446)
                     /locus_tag="KB913_002353"
     CDS             complement(1682..2446)
                     /locus_tag="KB913_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBB6820685.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     NAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2553..2828
                     /locus_tag="KB913_002354"
     CDS             2553..2828
                     /locus_tag="KB913_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBB6820686.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            3505..4455
                     /gene="yidC"
                     /locus_tag="KB913_002355"
     CDS             3505..4455
                     /gene="yidC"
                     /locus_tag="KB913_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBB6820687.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="KB913_002356"
     CDS             complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="KB913_002356"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBB6820688.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(5605..6063)
                     /locus_tag="KB913_002357"
     CDS             complement(5605..6063)
                     /locus_tag="KB913_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6820689.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIALDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIATLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            complement(6060..7523)
                     /locus_tag="KB913_002358"
     CDS             complement(6060..7523)
                     /locus_tag="KB913_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6820690.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGIKIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEKGRAGDLS"
     gene            complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="KB913_002359"
     CDS             complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="KB913_002359"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBB6820691.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPKIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFETWENIN"
     gene            8598..9347
                     /locus_tag="KB913_002360"
     CDS             8598..9347
                     /locus_tag="KB913_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6820692.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
     gene            9614..11092
                     /locus_tag="KB913_002361"
     CDS             9614..11092
                     /locus_tag="KB913_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HBB6820693.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(11160..12251)
                     /locus_tag="KB913_002362"
     CDS             complement(11160..12251)
                     /locus_tag="KB913_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HBB6820694.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
BASE COUNT         3841 a         2511 c         2092 g         3908 t
ORIGIN      
        1 aaagaaaggg gctatcccca gactttagta ggcgtcatta gctatctttc gttagcattt
       61 aaaggcgaac accatcacct attcacttcc attaaaagat agcatatttt tctgtaaaaa
      121 acaataaaat tatcgttctt tctttacacg ttcagcaaat tcatagaaag gagccaattt
      181 cgttaactgt tgattacatt ggtcactatc atgacaaata taattcccct ttttcgtata
      241 cgtgccatca gaacctgctt tcgttgtaga aagaaaaagc gacacattcg atgttttctg
      301 acagattgca cagattccct tatttatcgt tggtgataaa gtaccgctaa tcccttttaa
      361 tttttcatct tcgtaataga ccatgaattt tttctgcgta cctggatcat tccagccgat
      421 gtacgtatgt tcttgcaagt cgatttcatt ccaagctggt tgtttgagtt ttttcacttt
      481 tcggaataat ttctcgattt gtggtttgct aggctgcata aacggctgga cgatttgctt
      541 cagctcctcc aatgctcttt ctgcttgcgc ttttgtcagt tttacgtcta aaactgtcgt
      601 taaaaatgta tcgatttctg gcagttcgtg ttctaatatg tctcgaatct tttcagctgc
      661 tagtgcctga actgtttgta ccgtttttgg atcattgaca gatgagtacg catttaataa
      721 ctgatctact tctcttttta taaaaaaata ttggtatggt tttattgttt gttccatgat
      781 tttaaagtcc tttcttctaa ccaaagtgca tactttgtag aaaaaagtga tcttctgcaa
      841 agtatgtgtt acctgaagat cccggactct tttaaataag atacgttttg catcttatca
      901 tcaccccctt taatgttcat tcttctatgt acatgattca ttcgataaat aaaagtaaac
      961 cgtatcttga acagatagtc aactgcaaac agaaaaaacc gagaaaatca gccagatttt
     1021 ctcggaatat agtctattat tattggtttt acctattaaa tcgaggattc tttcccaaag
     1081 taacgttgcc atctcttacg catacttgca gacatgggct gagccgcttc tttgactgcg
     1141 cagtatttgt ccacgaatgt cacaatatat ccttctttat acttaggcgg tgcgatcgtt
     1201 gcaccccaca tgtgcttcaa aatgatatct cgctcaagat ccgacaaatc ggtgattttt
     1261 tctgcattct ttacagcaat tcttggatgg atatacgcat gtgtcccctc gtcaaatttc
     1321 gtcgtacgcc aatcatagta gaacagatca tgcaaaagtc cagcacgcgc tgttgcttta
     1381 gcattgccac cccatttttt tgcgagcaga taactatagt aagaaacact gatggaatgc
     1441 tccaaacgag tggaatgaac atgctgtgtg taattcgcta attttttcac tgcttctgtt
     1501 tctaaaagat cttgtacata agacatatat tcttcgtctt cacgccattt ttctgtcata
     1561 attatcgatc tgccaccttt ttgaatttca ttttcttctg aaattgatct aagtatacca
     1621 ccagtgttcg gattattcta gtcgctctag ataaaatagc taaagcttaa tagttcctta
     1681 atcataaaga aaaatgataa agaacgatcc ctgctgcgac tccgacattc aatgattccg
     1741 catttccttt cattgggata tatacgttct gatcagtcaa agacaagatt tcctgactta
     1801 ctccctgacc ttcgtttccc atgattatag cgaaatcctc tgttttttct actttgtcta
     1861 atgcatgtgc ttcttcattt aattctgtac cgtacaccgt aaaccctttg cctttcatta
     1921 cagggattac atctgccaaa tctttttgta acacaggcaa atgataattg cttccctgca
     1981 tgcttcgcag cacctttgta ctataaatat ctgccgttcc tttacctaat aaaacaccag
     2041 ccataccaaa cgcatctgcc gtacggatca tcgttcccac atttccagga tcctgtacat
     2101 tatctagtaa aagccagcct cctgaaaaat ctggcgtatc ttcagatgtt aacgtcatca
     2161 ctgctaagat cccttgcggt gtaggtagat ctgacatagc ggtcatgacc tcatctgaaa
     2221 ctagaaaagt agaaatctct ttgtttacag ccagccagtc tccccattct ttcatacctc
     2281 tctgtgtcac aaaaagttct tttatttctg cattagacga cgcagcttct tcgatcagat
     2341 ggaacccttc caaaagatat tctgcctttt cttctctgta tttcttttta tgtagttttt
     2401 ttaattcttt gattcttgga ttttttgctg attggatctc tttcacattc ctcacctcaa
     2461 ctgattatat catggaatag gtgcttgagc ttgtttcatc ctaaaaaaat cggtatcatt
     2521 gatttataaa acaggaaaga aaggtgacga acatgcgcaa agttaaaatg aatgtccaag
     2581 gacgtgtcca gggcgtggga tttcgctata tgaccaagat ggttgctgat cagttaggcg
     2641 tgaccggaac ggtaaaaaac gaagacgacg gctcagtcac aatcgaagca atcggaaatg
     2701 acgacatcat ccaaaaattt atcgaagaag tcaagaagtc tccgagccca agtggacgag
     2761 tgcagtatgt ggatgtccaa gaagatccga tgattgagga acgaaagaaa tttgatgtag
     2821 tgggataagg ttgtgaaaag gtcgcttagt tttgagtatt aaggaaaatt ttgtgaaaat
     2881 ggctttccac atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg
     2941 tcgataaggt tgtttttgaa gcgctttgcc tcgagtatta aggagaaaca ttttcaaaat
     3001 agcttctcat attttgaaat gtaatgactt aataccgaga ggcagctgat aaaacaccgt
     3061 caataaggtt gtgaaaaagc tggtctgcat caagcattaa ggactggttg tgataaatag
     3121 ctctccatat ttttcaacag gctggactta atgccgtaga tgcaagcttt tgaacaccgt
     3181 cgataaggtt gtttttgagg cgctttgcct caagtattaa agacaggtag taaaaaagct
     3241 gatctataac ttgcaatgaa tttgcttaac ccatattttc cagacagaac aaaaaagttt
     3301 ttagtttttt aaataagaaa gaaacacttg gaatcactct tttctttcta agtatttctt
     3361 tcttgatttt ttgtcttttt tcaaaatttt tcgctacgaa aaagaacgaa tatttatatg
     3421 aaatttctat gaagttgatt gaattccatg cgctttttta gtatagttaa gtttgtgtaa
     3481 aaattataga agaggaagta ttctatgaat aaatggaaaa actggttatt gggatccgga
     3541 cttgtcagta tcctgctctt tttatctggc tgtgtgcgga tggattcaaa cggaaaccct
     3601 gacacttcag gaatcgttta tcgagtactc gtccatccta tgggccaagc gattacatat
     3661 ctagttgaga atttcaattg gtcttacggc tgggcagtta ttgcaatgac tgtgatcgtt
     3721 cgtatcatca tcttgccact aggtatcagt caatcgaaaa aaacaatgat ccaatctgaa
     3781 aaaatgcaag cgttaaaacc acaagttgaa gcagcacagc aaaagctaaa agctgcaaca
     3841 acacgtgaag aacaaatggc agcacaagca gaaatgcagc aagtatatcg cgaaaatgga
     3901 ttgagtatga ccggcggaat cggctgtctg cctctattga tccaaatgcc gatcttctct
     3961 gccttgtatt ttacggcacg ctacacagaa ggtatccggg aatcatcttt ttacggcatc
     4021 gatctaggct caccaagtat ggtgcttgtg gccatcgcag gggtcgctta tctgcttcaa
     4081 ggatatattt caacaatcgg tattcctgaa gaacagaaaa agacgatgcg tacgatgctg
     4141 atcgtctctc ctgctatgat cgtcttcatg tcaatcagtg cgccagccgg tgttacactt
     4201 tactgggtag tcggtggtgt gttcagctgt ctgcaaacat tcatcacaaa cgttatgatg
     4261 aaaccacgtt tgaaagcaca agtggcagaa gagttgaaac aaaacccgcc aaaacaagtc
     4321 gtcactccaa gaaaagacgt gacagaatca gcaaagccag ctaacaacaa acaagcaaca
     4381 aaacaaatca aacaaccaaa aaacagtaca aacaacaaag gccgcaacgc aggaaagcag
     4441 cagaagcgga agtagatagt aaataagagt gtaataaaaa ttcattaaca gttttagcaa
     4501 ttaaaaatat cgaccaagat ttttgaaaaa gaaatctggt cgatattttt atttaagtga
     4561 atgtttaatt tgaatcatcg attgatcgct atctaattgc agcagcatct ttttatgaag
     4621 aaacaacttt ttcttatcta tcaacgtaga caggtgttgc tgtttcttct aatagtgtac
     4681 ttaattcttt aatattttgt tttccttctt ctaacatcca actactcgct ttttcttcgc
     4741 cttcggtaac aaaaggtgcc actcccttcg cccatgttgc tcgcccacat aagacaccat
     4801 tgaatgtcga acctgattgt tttgcaaaac gtaatgtatc ttgaaatagc gtagcattga
     4861 ctcccgcact taaaaaaata aacggttgtt cagtcacttt cgattgttca tagaaatacg
     4921 cggatgcctc tgcttgacta taacaagtct cttgcccata tccttccaca aatctcatat
     4981 tcactggcac ttctactttc aatacatcca cttgataacg ttcttttgaa aattctcgca
     5041 tggcttcaat aactttatgt ggttttactt ttgcataggc aagagaagac ggatcgccaa
     5101 tagttgcatc ataagaaaga atctctaaaa agaaaggtat gccttctgct tcgcattctg
     5161 aaccaatccg ttctataact atttgttttt gcacattaat ctctgctggt tcatcaacgt
     5221 catagtacaa taaaaattta caagcatccg caccagcttc ttttaacctt ttcaccgacc
     5281 aaatattcaa taaatcaggt aatcttcccg gtattttcgt atcatagccg gttttttcat
     5341 aagctagcag taagccacat tctttctctc gaagcgctgc tgcaggcagg ccgtattctg
     5401 gatcaagtaa aatagctgag gcatagggag tcaggtattg agaaaccatc tgtttaaatt
     5461 ggatgatgtc ttctgatgta gcttctttat attggttgat cattttcttc aaagcaccac
     5521 gctggtcgat tgctaatgcg ctaataattc cagcttcatc cgtcaatcgc ttcaaacgtt
     5581 cctgtttttc tatactcatc ttcttcatag atcttcacct atttctttag ttaatattgt
     5641 ggctatttct gtttttgatt ttgcttttct caactgttct gtaacctctt ttcgcatcaa
     5701 tgatcgtgca acgagagaca ataatttcaa atgagtcgtt cctgcttctg aatctggaat
     5761 aaataacgca aaaataaaat caactgactg tctatctaaa ctgttccatt caattccttt
     5821 gttcagtgtg gcgataatca tactaggttc gttgattgtt tgagacttcg catgagggat
     5881 agcaaaacct gacattattc ctgtagtccc ttctttttct ctttctagaa gtttttgata
     5941 tacttctttt tcgtcaagag cgatccctaa acagaatgtt tgctttgcta aaaacttaaa
     6001 tgcttcttct tgactatcca atggctgttg taaaaaaatg ttctcttcat gaatgattgt
     6061 catgataagt ctcctgctct tcctttttcg ataactgtac gatttgctgc tttattatcc
     6121 atcttcttgt ctttatcagt tactcttttc ttttggatta atcctagtat cactccacca
     6181 acgatcgaac caataagaat cgctgtaacc cattggattt ttcccgtcac tacaggtaac
     6241 actaaaaaac caccatgtgg tgctggaact tggacgccaa acaaataagt taagacagca
     6301 gcaattgatg agcctaacat catcgtgggt aacactcgga tcgggtcttt cgcagcaaac
     6361 ggaatagctc cttccgtaat atgagttgat cctaaaataa aattaaccaa acctgcatta
     6421 cgatcattgg tatcaaaata tttaccaaac aataaagtag caaaaccagt aatcaacggt
     6481 ggtgcaatac aagctgctga cacaccagcc ataaaagtcg tgtttccttg tgccaaaaga
     6541 gctgttcctg ttacatatgc cgccttatta accggtcctc ccatatcaaa cgcacacata
     6601 cagccaacaa tcacgccaag aacaagtgga ttcgaatgtt caaatccagc taaaaagctc
     6661 atcattcctt catttatagc cttcattgga cctgccagca aagacatcac gatgccaata
     6721 aatgctacac caataactgg atataagaag attgccttca agccatctag ttgtttaggt
     6781 aaaattgtca gtagcttttg caaaaataag ataaaataac ctgctaagaa cccagctaaa
     6841 atacctccta aaaatccagt accgccattc atggctacga ttccaccaac aaatccaacg
     6901 actaaccctg gacgtttcgc gatcccttct gcaatataag ctgctaaaac tggaaccatc
     6961 attcccattg ctgcatcgcc aactgctttt accattgccg ctgtagcatt gtattgtgca
     7021 tgatctggat caaaagaata gattccccaa acggcaaatg aaatagcaat caatactccg
     7081 ccagctacca cgaaaggcaa catatgagag acaccgttca ttaaattttt atagatgcta
     7141 cgaccaaaat tagcaccact catcgcttct ggttctaaag tatcagcagc ttcattatct
     7201 gctaagacag taccttttcc tgccaatgct tcgtcaatca gccgttgtgc atccttgatt
     7261 cctgtactga cagaaacatc aatgactcgt tttcccgcaa atctttctga atggacatct
     7321 ttatctgcgg caataatgac agcatctgcc tgtttgattt cttcagccgt taattcattt
     7381 tcgatcccaa tttgtccatg ggtctccact ttgatcttga tgcctttttt cctagctgct
     7441 tgttctaatg cctcttgcgc catgtaagta tgcgcaattc ctgtcggaca accggttgct
     7501 gcaattagtt gatattttcc catgtttcaa acctctcttc cttgattttg atttgtttac
     7561 ttaattcctc cacatccaaa aaatcagtca gtcctttacg aaaagcggtt gagctgcctg
     7621 ctgctatgct tttacgtaac gtttcatcaa gcggtcgtcg attcatatat cctgctaaaa
     7681 aagcgcctaa catggtatca cctgcacatg ctgtattgac aacttttcct tttggcgagt
     7741 ttcctcgaaa caccctgtct ttcgtaaaaa gaatcgctcc tttctcaccg agggataaca
     7801 aaacattttc tgcacctaac tctactagtc gttgtccata aacaaagtaa tcttcatctg
     7861 taaccatttt tcgtccgaac caagaagaaa gttcttcctc gttcggtttc agcaaaaacg
     7921 gtcgataggg taaacaatcc atggcttctt gatcactact atcaataatc aaatgaatcc
     7981 ccttttcctg acaaatccga ctgatttcta ttaaaacctt tggagacagc cctcttggta
     8041 aactcccaga aacacaaaga taatcttctg cttgtaatgc tcttatttga tttaaaaaat
     8101 tatggacagc tgtctgcggt attttaggtc cttgattcac taatttgtat tcttctcccg
     8161 tttgattgac ttgtgtaaat acattgatac gcgtcatacc aggcacttca ataaactctg
     8221 tttggatttg tttctgctgt aaatagtctt ctatatactt tcctgtaaac ccagcagaaa
     8281 aacctaatgc cgtacttggg aaatctagca tttttaatac tagtgacaca ttcacccctt
     8341 ttccgtttgc ctgaatgtca tcctcttttg tgcggtttac cataaaagga tgcatctcct
     8401 ctgtttcaat aaatagatca attgccaaat tcatcgtgca tgtgtagata gacataacca
     8461 acgacctcct tgactctatt atgaaatacg cgaaagagaa aatgttttct taatcgtccc
     8521 aacacaaaga aaacctttac atttataaac tcgtcgtgct attttttaac taacttttgg
     8581 tgaaagaagg aaagaatatg gatcacaaat taagtgaaac agaacagtac ctctggaact
     8641 ttatcgaaca ccacatccta gagatcccta actactccat cgtgaaacta agtgaacaag
     8701 caaatgtctc aacagccacc attgtgcgga caatgaaaaa gaaaggctat gaaggattta
     8761 cttcgtttaa gcaccatcta aaagaaggag aaaacaagaa catcaatttt tctttcttag
     8821 ataaagtaga caaaggtatc cgtcgagcca ttctaaaaaa tgaacaagaa gtggtacgta
     8881 cgatcaatat gttggaaatc ggaaatattg aggatgcaat acaaagaatc aaatttgctg
     8941 accgggtttt tgtctttgca cgaggatttt cagaaatgat tggtcaagag atgctcgtaa
     9001 aacttcaatt aacagggaaa aattgtcaaa tgcatactga tccagaaatc atcaaaagca
     9061 tcagtcggaa actaactaag aaagacagcg ttatttttgt ttctttgaac ggcgagacaa
     9121 aagaactcgt caccgccgca aagaattgct atgatgcaga gattggttcg attctagtta
     9181 cagccaatca ttcctctaca ctgaaagact attgcgagat caatctcgta ggtttcaaat
     9241 cagaaggttc ttatttccct gattatgaag tacggtcacg tttgcctctc cagattatag
     9301 cgagaatcct gcttgacgcc tatgtattgc gtatggggga gaattgaaaa gcagtttatt
     9361 atggttggtt acagtttaaa acatcacatt ttttattctt tatattgtat ggactcacgg
     9421 aaacttttta tgtataaagt tattcacaat ctataaagtt actttaaata acaaaaaaat
     9481 aattgaaaat acttaaaatc aaaaaatatc tttttaatca ataaaaaaat tgacagtttt
     9541 attaataata agctattctg ttatagaaga aaaaattgtt tgttattatt agcaacaaaa
     9601 aaaggagtgc atcatgaaaa agttatctca aaaacgttta gctcaaatca ttattgattc
     9661 tagaaaatct ctgaaaatga cacaacaaca acttgcagta gctactggta tcaaccgtgc
     9721 cttaattagt cgattagaat ctctcgattt tatcccgtca atacaacaat tagaatcatt
     9781 agcagaagtt ctaaattttg aaccaacaga tctatttata aatgaatcaa ataaatcaaa
     9841 cagaacaaaa catcagtcga agaatattgc tgtagccggt actggttacg taggtctttc
     9901 cattgctact cttcttgccc agcacaatca ggtaacagca gtagacattc ttcctgaaaa
     9961 agtaaaacaa attaacaata agaaatctcc aatacaagac gattacattg aaaaatatct
    10021 agctgaaaaa aatcttaatt taattgcaac gactgatggt gcagccgcct atagagaagc
    10081 cgattttgtt gtcattgctg ctccaacaaa ttatgatagt aaacaaaatt attttgatac
    10141 ttctgctgta gagtcagtaa tcaaattggt gttagaagtc aatccaaagg caataatggt
    10201 catcaagtcg acggtacccg taggctatac cgaaagtatt cgtaaaaaat acaatactaa
    10261 aaatattcta ttcagcccag aatttctcag agaatctaag gcattatatg acaatctata
    10321 tccttcgcga attattgtcg gcacggacca aactgacaaa actttacgag aagcctctca
    10381 cacttttgca gatttactcc aagaaggagc aatcaaaaaa gatatcgaaa ctcttttcat
    10441 gggattcaca gaagctgaag cagttaaatt attcgctaat acttaccttg cacttcgagt
    10501 atcttacttc aatgagctgg atacttatgc agaaatgaaa ggactaaata cacaagaaat
    10561 cattcacggg gtttgcttag atccaagaat tggcacacat tataataatc catcttttgg
    10621 atatggaggc tattgtttac cgaaagatac aaaacaactt ctcactaact ataacgatgt
    10681 tcctcagaat atgataagtg caattgtcga tagtaatcgt acaagaaaag actttatagc
    10741 agatcgagtg ttagaacttg ctggcacgta tgaggctaac agttcgtgga atgcagaaaa
    10801 agaaaaagag gtagtcatag gtgtataccg tcttacaatg aagagtaatt cagacaactt
    10861 ccgtcagtca tctattcaag gagttatgaa gcgaattaaa gcaaaggggg caactattgt
    10921 aatttatgaa ccaacacttg aaaataacac tacatttttt ggttcaaaag taataaataa
    10981 tttagatgat tttaaaaata tcagtcacag tattattgct aatcgttacg atagtaatct
    11041 tgatgatgta aaagaaaaag tatataccag agatttattt caacgagatt aaaaaataac
    11101 acctcagatt tgtagtgtct gaggtgtttc tataaacttt tataagtaaa aaaatacaat
    11161 tatacttcat aaaaagactt ataccactgc gcaaatttac gaagcccgtc acgcaaactt
    11221 gtacttggtt taaattcaaa atctcgttct aacgcactag tatctgcata agtaactggc
    11281 acatctcctg gttgcattgg aactagttcg gtatgagatt caaagtcgta atcttctggt
    11341 agcacccctg ctgcaattag ctcttgttgt agaatatcta caaaatctag taggttttcc
    11401 ggcgtattgt taccaatatt ataaatatga tatggtggga ttggtagccc atcttcccca
    11461 tcaattttct ctggagcgca ctgcataacc ctctttactc cttcaacaat atcatctata
    11521 taggtaaagt cacgcttgca attcccataa ttgaatattt ggatattatc accagcacga
    11581 agtttatcag taaaaccaaa ataagccata tctggacgcc cagcaggacc atatactgta
    11641 aagaaacgta accctgtaga cggaatattg taaagtttag aatatgcatg tgccattgat
    11701 tcattacttt tcttagttgc tgcatacaac gatacttgat tgtctacttt atcctctgta
    11761 gaataaggaa ttttcttatt agtaccataa acggaagacg atgaggcata cactaaatgt
    11821 tccacaccag attctccatt atcatatgaa tgacgacaag cttcaagaat attatagaat
    11881 cctattatgt tagattcgat atacatatct ggattagtaa ttgaataacg gactcctgcc
    11941 tgagctgcta aattcaccac gatacttggt ttataattat caaagatgaa atcaattgtt
    12001 gctttatcag caatagaacc tttgataaaa ttccaagtag atcctggatg gttctttgcc
    12061 tccgtttcta tctctgataa tctatagttc ttaatagaga catcatagta atcattcata
    12121 ttgtcaatgc caatgatttt tattgatgac tgagtacgta ataactcaag aaccaaattt
    12181 gatccaataa aaccggctgc gccagttatt aatattgttc tatttgataa ggacgtgttt
    12241 aattccagca ttttttagca ctcactttct ttttttctta tgaatacata tttgttatat
    12301 attaaaaaat cttatttaga cttatctatt gtcactttta tcattctaat ct
//
LOCUS       DADVXE010000076        12198 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.078, whole genome shotgun sequence.
ACCESSION   DADVXE010000076 DADVXE010000000
VERSION     DADVXE010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12198
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.078"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(31..1383)
                     /gene="celB"
                     /locus_tag="KB913_002363"
     CDS             complement(31..1383)
                     /gene="celB"
                     /locus_tag="KB913_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBB6820695.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(1383..1901)
                     /locus_tag="KB913_002364"
     CDS             complement(1383..1901)
                     /locus_tag="KB913_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820696.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(1917..2243)
                     /locus_tag="KB913_002365"
     CDS             complement(1917..2243)
                     /locus_tag="KB913_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBB6820697.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(2256..4235)
                     /locus_tag="KB913_002366"
     CDS             complement(2256..4235)
                     /locus_tag="KB913_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6820698.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(4256..4570)
                     /locus_tag="KB913_002367"
     CDS             complement(4256..4570)
                     /locus_tag="KB913_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBB6820699.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4738..5031
                     /locus_tag="KB913_002368"
     CDS             4738..5031
                     /locus_tag="KB913_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBB6820700.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(5109..6221)
                     /locus_tag="KB913_002369"
     CDS             complement(5109..6221)
                     /locus_tag="KB913_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6820701.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            6608..6787
                     /locus_tag="KB913_002370"
     CDS             6608..6787
                     /locus_tag="KB913_002370"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820702.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            6981..7151
                     /locus_tag="KB913_002371"
     CDS             6981..7151
                     /locus_tag="KB913_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6820703.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(7575..10975)
                     /locus_tag="KB913_002372"
                     /pseudo
     CDS             complement(7575..10975)
                     /locus_tag="KB913_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(11647..11915)
                     /locus_tag="KB913_002373"
                     /pseudo
     CDS             complement(11647..11915)
                     /locus_tag="KB913_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT         3635 a         2575 c         1983 g         4005 t
ORIGIN      
        1 tttttgtcac agttcctttt ttcttagaaa tcattttaac ttttcactag ctaattctgc
       61 tgccttttct ctttcttcat ttaataattt attatcatag aatttgataa atgggaacca
      121 gataatgaat gcgatgattg cacaaatgac tgctaacaca gcagctttcc aatcaccacc
      181 actaccaaca aatgctccga tcccgactgg tgaaggccac ggcatctgtg caagcatcgg
      241 tttgacgatt tccagccgaa tggcaaaata agcgagtgta gcagaagcca tcggagctaa
      301 gaaaaacgga accgctaaat agggattgta gacgattggc atcccgaaaa tgattggttc
      361 attgatattg aataatcctg gtacaagtga ggcttttcct aacactttca gctgatcaga
      421 tttcgcgagg aatgcaataa agatgatcaa tcctaaagtc gcacctgatc caccaacggt
      481 tacataagaa ttgttgaatt ctcctgccaa cggataattt gcgccttgtg cgttagctgc
      541 catattagct aatacgatcg gggtcaagaa agaagtgatg atattcgctc catggatccc
      601 tacgatccac aatgcatgga tcaagaaata aatcaccatg acaccaagcc atgtattcgt
      661 caactgcgta acaaacccaa atgggatagc aatcattttg aagatatccg ttcctagtgc
      721 aactaataat ccattgatga tcatcaccac aaacgcaatg acaaatgttg ggatcagagc
      781 agtgaaagaa cgagaaactc ctggcggaac aacatctggc atttttatga cccaatttct
      841 cttgacacac atacaataca attcgaccgc aataatcgac ataataatag ctgtaaagat
      901 tcctgaagtt cctaaacgtt cgacaaaaga gcccatccta ataccattta ctacagtttc
      961 tgtctcattg atagaagcaa tcaagctgat tttaccatca gtcatgatca attcagggat
     1021 acacataaag aatgcaaaaa cagatagtaa tgcccccgtg agcggattaa catttaattt
     1081 ttgttcatct cgttcaattg acgttaattc ataagcaaac acaatggcaa agtaaataga
     1141 taaaatcccc atcgtcattg tattgacgat catgtacaag tcactaactt tgaaaaaagt
     1201 tgcattaaaa aatccttcta aaaatgggaa cggtaatggc aaaatattta aaaccaaaaa
     1261 catcgagcct acaatcgtga aaggaataga agccatcccc gctgccatga cagcccgaac
     1321 gattttaagt tgcgcaattt tccccatagg tcccatcagg tatttctgca aaaaatcaaa
     1381 cattagttat tctcctttcc taaatataac gctttttcat attgtttaat acggatatac
     1441 tgttggtctt ggttgagtga aattttcttt aaacgatact gtataaatgc actggcaaaa
     1501 ataccgctta caacaagaat gaaaacaaat aactgtcctc cattgttatt tgccataaaa
     1561 ggatacaaga atgtaaatcc tgaggtaaac aacactggaa tcactaataa attaaagaca
     1621 ctctggaaca aaaaatacca ctttgtccat ggaacgttcg tttggtgttt tcgataaagc
     1681 tttacttgtt ctcctactgc aggcaaaata gctaaaatca gaatcatcgg taaactactt
     1741 cctaaacttt tagctgatag aagcagaatc atccattgca tgttcatgaa aaagaaaaag
     1801 gcagtcaggt aacgtacgat tagataacga ttgaaataca tgtttttcaa actaagttgc
     1861 tttttttcta attcgatttt cctttttact gtatcctgca caatgatcct tcctttctat
     1921 ttattttttt gatacaaata attcatttcc tgtgcaactt ccaataatgt catcgtcgtc
     1981 atcagatgat cttgtgcatg gaccatgata atttccattt ctatttttgt cccgctggca
     2041 tattctttca gaagttgagt ttgtgactga tgcgcatgaa gaatctcttc atttgcttgt
     2101 cgcaacttct cttctacttc ttcaaacatc tctttacgca tcgagcgaaa tgcttcatgt
     2161 atcagtgtcc gtgcatttcc gctatggaaa atgatatcaa aagaagtcac ttgtagtgtt
     2221 tcactgttta ttttttcagc catctgtttt cctccttatt cgatcagttt gataaattta
     2281 ctgctgaaat tctcaaaaat aggttcagct aagatttcct gctgtacttt tagctggtca
     2341 actaacctaa cgattgcttt agtcacgacc gtaattcctt cattttcgac ataagaaggc
     2401 gaaactaaaa aaacaaaatg aatttcttga tattgatccc actgcatccc agaaggaatc
     2461 aatgcaacgg ctacctttgt ttcgattcca actggaacag cgggatgtgg gactgccact
     2521 gtatcactga atatgatttg tcccatattt tcacgttgct ggatctgctt tcgcatttct
     2581 cttatatatc cttcttcttc atttatgctc agcttttgca gcaaatcatg aagaatttct
     2641 tcctttttcg gttcgtacgt ataagtcttg aaaaattttt cagacaactg ttcggtgtaa
     2701 atctgctttt tttgctgtag agaaaatgct ggtatcggtc tatctgagga atgatagggt
     2761 atagattctc caactacctt tcgtatttta cgaacatcat cttcattcaa aaaaatactg
     2821 acatgtaaaa ctggaatttt gaaaaacatt gtcgaaagat caatagaaga aataatcagg
     2881 tcgattcctt ttaaagttgt ttcattgatc tcataatagc cttttacact taccactgta
     2941 atatttttac cgaattcact gactacgcga ttctttaata gttgggcact gccgtaaccc
     3001 gttgcacaga taatcaatgc atgtagttta tgcgcagctc tttctttttc caatgccgcc
     3061 atgagatgca aagccaaata ggcccattca tcttcattga tggtatagtt tttcaaagcc
     3121 ggcatgttgc tgaaatgcct ttttactgcg tcaaagactt tgggattttc tttctttatc
     3181 tcctcagtca atgggttctc aatgcgaata cctcggctca atcgaatcat catcggtgac
     3241 aaatgatcga gtagtccatt gaaaagctgg agatcctcta ctaatgaaaa atgaaattcc
     3301 tgagacaatc ttttcagaac tttcgctaat tcctttgata gttcctgatc attttgattt
     3361 tctttgtgat tcgacttagc catgagatgt aatgtcaaat aagcaatttc ttcttcggga
     3421 aacgatacac ctgcgattac ctcaatacgt tgaacgatcc gctgcgccac ttgatactct
     3481 actcgcttag aaacttcttg ttcgatgcct aattccttga tttcaaaccc ttctcggagc
     3541 cgtttgatcc ccaaagccaa gtgtaaagtc agattctgta tgataaaatc cgaaactttt
     3601 aacttagctt ctcttgtttc atcgagaatg ataatgacta gctcttcaaa actgatgtct
     3661 gggaaaaaac ggctttgccc taaatattct ttcaatgaat ttccataatg gtttccaaaa
     3721 aaagtatcca tgataaaatg ccgtcgattt ctttcttccc cttcgatcca tgtcccttga
     3781 ccatgcttag aaacgatttt tagtgaatat ggaatcaatc gctccttgat ttcttgcatg
     3841 tcctttgtca aactggaacg actgatataa agctcttctg ccaaatcatc cataaaaaga
     3901 atggcatctt ccaaaagcaa ttggttcaat atatactttt gtcgatcttc ggactcataa
     3961 aatccttgcg gttctctagc atatccaggt actatttctt gccgactcaa aaacaagtca
     4021 aatgtcagtc tttgtaaaat atgcagttgg tagccataac ctggtttagc aatgatctta
     4081 cctccgtttt tttctactaa ctctttgatc cgctgcaagt aattacggat tgtccgatca
     4141 gataataaca attcagaagc taaacgttga ctggtgacat actccttctt gtgatcaatc
     4201 aaatatctca acagcaattt ttccttctgt ttcattatca tccactccta ttccatcata
     4261 tgttctcttc gatcacctct gctaacttct ggatgcctgt agggattggg acatacgctt
     4321 ggaaagggat actaacaaca ggctttccaa cagattctcc taattttttg aatttatcca
     4381 aaaacatcgt cgtttgcggg ctgatcagaa ataaatcaaa atcactattc ttaatcatat
     4441 tatcgccttc tgtagctgaa actgcatcta cgagtacctc ttctcttttt tgcttaaaga
     4501 aatccgttgt ctttgaggcc atcatcgagg atgacattcc tgccgcacaa ataatcaatg
     4561 cttttttcat aaatcaatca ctccttttat ttttataaac caagcatatc ttgtaagcgt
     4621 tttctattca aaatatatat ttccgtagca ttgcggaaaa aatgtgtatc atatcttgaa
     4681 taataatttc tggcaccgtg atatactagt gatagaattt tttcaggagg ggatttagtg
     4741 agtatcacag tgaatatttt gtatacaagt acaaatggac aagccagaaa atttgcagaa
     4801 gaaatggtcg aaagaaacat tgtcaaagcg attcgtgcag aagaaggaaa cgagaaatat
     4861 gactattact ttccactaga agatccagaa tctcttttac tgatcgaccg ttggaaagat
     4921 gaagaagcaa tcgaaaagca tcacaaatcc gaaatgatgg ctcaaataaa cgaactccgt
     4981 aaaaagtata aattaaaaat gaaagtcgaa cgtttcactg atttaccgta aaaagataca
     5041 catggaatga tagcaattta tcatccatgt gtatcttcac tttttcctta ttttttattc
     5101 gatctcatct aatgattcaa accgtgtttt tctcttattt ttcggataag tatttcagtc
     5161 accccaatat acatgattcc taaacatacc ccaaggatat tctcaaaaat gcggatcgtt
     5221 actgctcctg gaaccccgaa taaactggca gtgattgcca aagcaccaaa agaattaaaa
     5281 actgttttat atctataggt agaacaaaca cctaaagcta gaccacctaa tataccgacc
     5341 cagttaaaag gaataaattg gctgatacca ataaataaaa cacatccaat caatgagcca
     5401 atgattcggt ctactgctcg ttctttgaaa ccaatcgaca tcaatccata gctagataca
     5461 atagaagaaa atgcaaaccc tgcccacatc aatcgctgaa aagggacata ctctcctgca
     5521 acgatcaaaa gactaatgcc aaatgcatag atgagcatcc aaattttttc ctgcgaatac
     5581 atgcctttca aaaaaatctc tttaaacaag cttttgtctt tgttcttttc tcgatgtttt
     5641 ctgtaaagga gaactgaaaa ccaacaaaaa aacaaaaata ataagctact tgtttgtgta
     5701 aagaaattct tgttcaacga atctttaggt aacgaataaa caataaagag atatgaaaag
     5761 ccgtacaaag aagcattccc cattttggga tcactagcgg ttgccattaa tatgctgctt
     5821 agtaaaataa aatgaatcaa catgcccata actgaccatt tgatcagctg gacatacggt
     5881 gctactaata gtgagaacat gacgattgct aaacctatga tcgaatggga aatcttataa
     5941 ccaaagtcaa caaaacgaat actcatcaac atacagaata aaaccacagc gtatggttta
     6001 tgcttcgatt caaataatgt tgtaattata atgataaaac aaatggcaaa caatacgatg
     6061 aataatgatc gtaaaaacaa tgaacaaata tacatgcact tttctttttt agaagctgct
     6121 tctcgtattt tttgttttaa aataaacgga tctagttgta gagactgata aaaatccacc
     6181 tgttgtcgtc ctttcttttt acttttattt tttacagtca tctatgacag gttgtaaata
     6241 ctatggaaca tcatatggcg ttgtcatttt cttgtcaact atttttccta ttcatgtttt
     6301 tataaaaaaa catatcgttt tcttgtatga ttaaatcacc acaaaataaa caactgagag
     6361 aacgatatgc tttatgaatg gttctatcaa aaaaattctg agatcaatag acaaaaattt
     6421 gatgattaca gaggtctctt acgaaacctt acagaagaaa aaaacattga tcgttgctgc
     6481 agttctcttc cctgctccat gtgtctgtag aaattgtggt tctgctgtgg tagatggaaa
     6541 taggaaatta atggtggtga aaaacaagaa gaaggaaacc attgtccact ttgaataata
     6601 taatcatatg ccaatggtta tacgcctaaa aaagcagcgc tatacctgta aaaactgtcg
     6661 aagccattgg aacgctcaaa gttattttat ccgtccaagg cactcgattt caaatcatgt
     6721 cagacataaa atcacttctt tactgactga aaaagtgtcg ttatttttta tttcgaaaag
     6781 ttgttaggta tctttgacaa ccgttattcg cacattgaaa gagttgagaa gctatttacc
     6841 aaagtcttcc aaaagaattc tgtcttgagt gttgagggtt gtgaatttcg ttctcacgtt
     6901 tccgttgagg ataaactgag ttttatttcc gcggatggcg agacagaaaa attaatcgag
     6961 aaaatttacc tacacaaaaa attcctcgat taacaaacta tttccttagc tgcactaatc
     7021 ctaaagaaat agaattctta gttacagaca tgaacgccac ctactttcag ctcaccaaac
     7081 atgttctacc aaatgcgaaa ttggtgattg atcgattact tggtttttcc acgcctttca
     7141 aggaggcgta acctttattc acgagttggt tgaagctttc cgagacaaaa gacccgactt
     7201 gtttttctcc ttattgacaa agagccatta aaactagaga aaaaattaca actgatcgct
     7261 gattatttgt agaaagaaaa tcaaagtatt acccaataaa cttgagtcat taggcaaaaa
     7321 acactgcgaa actcaagaat gattttcgca gtgtttttgt atatttttta ttaactagta
     7381 ttactacaaa ggtttatttt tcacttctca acgcagcaca aaattgtctt tacttattta
     7441 ctggttgggt tcaaccttct ctactccgat actaatattt gtttgtatac cccttctaaa
     7501 atcggtagtt tccattcaat tgatgggtac tagttgattt taaaaactat gcttattcaa
     7561 ttttttattt tagctcatat atttcgtttc tttctaaatt ttatactgat gaaaacaagt
     7621 agcacaccca atattgacaa tataaactgg ctaatgatgg tttctccagt ttttggaaga
     7681 tgcttatttc cactgcttgt tggattgttt cctcttatat ctgagctatc agcaactttt
     7741 ctattctctt ttgttaaaaa gatcgccact tcttgttctt tttcgatctt gaaagttact
     7801 ggtgtcgcat ccaattcata ccctattggc gcttgagttt ctaccagctg atatgctcct
     7861 ggtgctaaac cgtcaattgc cagttttcca tcttctcctg tagttagacc ggtttgtagc
     7921 gtttctcctt ctcggttctg taactcaaaa acagctcctg caggatttcc ccgctttggt
     7981 catcgatctt tgtcaacacg acaccgcctg gtgtaagtcg gttttctttc gttaattcta
     8041 ccaccgctgt ctgacttctt tcgatctcaa actcgattgg tgtcgcatct aattcatacc
     8101 ctattggcgc ttgagtttct accagctgat atgctcctgg tgctaaaccg tcaattgcca
     8161 gttttccatc ttctcctgta gttagaccgg tttgtagcgt ttctccttct cggttctgta
     8221 actcaaaaac agctccttgc aggatttccc cgctttggtc atcgatcttt gtcaacacga
     8281 caccgcctgg tgtaagtcgg ttttctttcg tcaattctac caccgctgtc tgacttcttt
     8341 cgatctcaaa ctcgattggt gtcgcatcta attcataccc tattggcgct tgggtttcta
     8401 ccagctgata tgttcctggt gctaaaccgt caattgccag ttttccatct tctcctgtag
     8461 ttagaccggt ttgtagcgtt tctccttctc ggttctgtaa ctcaaaaaca gctccttgca
     8521 ggatttcccc gctttggtca tcgatctttg tcaacacgac accgcctggt gtaagtcggt
     8581 tttctttcgt caattctacc accgctgtct gacttctttc gatctcaaac tcgattggtg
     8641 tcgcatctaa ttcataccct attggcgctt gagtttctac cagctgatat gctcctggtg
     8701 ctaaaccgtc aattgccagt tttccatctt ctcctgtagt taaaccggtt tgtagcgttt
     8761 ctccttctcg gttctgtaac tcaaaaacag ctccttgaag gacttcacca ctgccttcag
     8821 catgtttaat tagttcaaca ccacccgtat caaggatgtt ttcaatggtt aacgtcactt
     8881 cttctatgga gtattcattt ataaaaacat catgtaccgt cgcatctaaa agataccctt
     8941 ccggtgcttc tgtttctcgg acttgatagc tacctacagg aagcggttca cttaaaaatt
     9001 ctccgttttc tgccgttata ccttcttgta tcacttgtga atcgcttgat aaaatttcaa
     9061 attttgctcc tgccagcctt tggccattct catcagtttt aattacttta atacgcccat
     9121 cgattttcct tgttcttaca gtactcgtat tcaatcgatt gtcactattc acaagcgttg
     9181 caaagtttaa aatttgatcg ccgaccgcat acgcctctac attgacctta aaagagaggg
     9241 taaaacttgt cggaccacca atcgtattat tcgcactgaa acgaactatt ccattattga
     9301 cttcggcatc aatgaaagag ggaatatctg atagaaatga cacaaattcc atgccttctt
     9361 ccaaaacatc ttcaataaca agcgtatttc ttgttccaga aaacatcgag acatgcagag
     9421 tatacgttag ttcattttca ttgagattga taacattttt gtccacactt tttcttaaag
     9481 agattgccgg aagattactt tcagggattc tcaagcggta gtctcggctc attacctgat
     9541 tattgtaggt catactcgct cgattccgag aaaacccatc ctcttgtctt ccttcattga
     9601 acaagtcgac atcggtcact tcaagagcat attcaataaa atacgattga ccctctgcta
     9661 gattaccaaa gtccacaaca agtgtattcg tttccttatt aaaagatact ttgtccacaa
     9721 attcctcgga aacataatga gttctaacgt ttgcttcacc tggattcgtt acttctgcga
     9781 tccgaacccc acctgaaata ggttctctat ttccagtgga actccatgta gtcggattcg
     9841 gtgccaaagt tgttccttgc ggtagtacat cggtaaccac tacaccgtct tttcgtgatc
     9901 cttcataatt tacctgcaaa ataaatttat tactgttggt cacgtcttgc ccgtcaatca
     9961 gcagattccc aagatttcct tggctgtcga tttctctaga gccatagtat aatttcgaaa
    10021 aaatgggtct tgatgaagga ataggcgtaa ttgaaaattc cgtgtttgct gctcgctcag
    10081 cataagtaag actcacttga aagtcattat ttggctcagt accgcctgat tgaaagaaag
    10141 caacttcaaa cgtgatactg aatgtatacg actgagcggc ttcatttaat ccttcataat
    10201 caaaggtaaa tggaaaaaca acgtctgtgc cttcttggta aaatgccagt ggctttaaag
    10261 gtgaatcatc agcgacctcc actctaatga actcaattaa gccaatcgat gctctaggaa
    10321 ctcgtacgac catctcccca tattcttcaa gaatatcgcc agcgcctcct tgaatgtatc
    10381 cctttaacgt ttgtgtatgc ctgctcggca aagtggggcg ctcagcagag atgccgatgt
    10441 cataattcaa gagctcctct tgtctttcaa tctgagattc ctgcgttata gatggctcag
    10501 atgatctggc ttcattaaaa gattcactta agctttcttc tggtatatta aaagattcac
    10561 ttgtgctttc ttctggtaca ttaaaagact cacttgtgct ttcttctggt acactgattt
    10621 ctattgagac cgtatttgat tgaatatcac cgcttcttgc ggtcaattcg tatttacctg
    10681 aatgctggga agaataagta atcagacgtt cgtaatcatt gagttgcttc acttcccctt
    10741 caatcaaatc ctcactctta tcaatgacca atgcatttag caggtctggt gttcctctga
    10801 ctcgcaactg gaactgctca cccaaagcag cctcctcttg atcaacttcg atcgtcagcg
    10861 aacgctctgg ctgttctgct aaagactcag ctagaaccgt tatgttccca aattgattga
    10921 tcacaataag cataactaga aacatactta acagtttatg aaatttgttc ctcactatta
    10981 ctccccctta taattttgac taaacaacaa ggtacccgat aattttctaa aaagattccc
    11041 caactcaaaa tggctgcgtt acctccctcg tattttcggt tcaactcaag cgttgcaatg
    11101 taagctgtaa acaaagctaa tgattgccga ttgtcttctg ttgattgatt cgatagcttt
    11161 gtatgacttt tagttgtccg tgtggcttaa ccataattat gatttcacga ttcctcctgc
    11221 cagtgccttg cacaagctgg agcgtaaccc taatagttat tttgttaatg tacttatata
    11281 cttttatact tttccattag aaacaatcac taaatcgttg ataccaaggt cagactctag
    11341 aatttcatca gtgagtccct gtattggtta accttcatca atcccaaaaa aatatatcaa
    11401 tgcttagcat caaaatgaat atatagttta gaatacttgg gattcatcga taactgatcg
    11461 cttatttggc catattattt ggcacttggt tcaactaaac gcatttagga tgttccttca
    11521 ttctcgtcat ggatgttctc aaaccgtcat tactaataaa ctgtccaccg aatcgatggt
    11581 tcatttcttg cattttccac gtccaattac tctttttgct ctttatttgg gcgtagtttc
    11641 actttcttaa cttgtatcgt cttccatcaa ctccttaatc atcttcttag ctttattggc
    11701 tcggtttcct tgtaaaaggt atctacaaat agtgacaatc tgtattaaat cttcatcatt
    11761 ttctgtaatg tcaataattt ctatattctg taccatatat tgcaaagggt ttcactaagt
    11821 tcataaccga agcgaattaa acaacttttg tatagaataa ctaccttttc tatttttcca
    11881 ttggtaattc tatctattaa ttggtttaat ccttttgttg tagttgattc cactaccaag
    11941 atgattctct cgaattttaa agcttgaaga tgtattgcta tttttgctaa ctggcgtatt
    12001 tgcaactatt tttcccttct attcttcctt cattgattcc cctctaaaat tactatccat
    12061 aaaaaattgc ataaatgaca atagtattta tattagtcat actgcttttt aacacagcaa
    12121 attccagaaa aacattcgtt acatatttgt gaatttttcc aaaaaataac atttttataa
    12181 aacgacgaaa aataaatc
//
LOCUS       DADVXE010000077        12131 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.079, whole genome shotgun sequence.
ACCESSION   DADVXE010000077 DADVXE010000000
VERSION     DADVXE010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12131
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.079"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(89..985)
                     /locus_tag="KB913_002374"
     CDS             complement(89..985)
                     /locus_tag="KB913_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6820704.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(978..1658)
                     /locus_tag="KB913_002375"
     CDS             complement(978..1658)
                     /locus_tag="KB913_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6820705.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(1659..2441)
                     /locus_tag="KB913_002376"
     CDS             complement(1659..2441)
                     /locus_tag="KB913_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6820706.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(2434..3351)
                     /locus_tag="KB913_002377"
     CDS             complement(2434..3351)
                     /locus_tag="KB913_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6820707.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(3515..3838)
                     /locus_tag="KB913_002378"
     CDS             complement(3515..3838)
                     /locus_tag="KB913_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820708.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            4626..7853
                     /gene="fss3"
                     /locus_tag="KB913_002379"
     CDS             4626..7853
                     /gene="fss3"
                     /locus_tag="KB913_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBB6820709.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            7966..8280
                     /locus_tag="KB913_002380"
     CDS             7966..8280
                     /locus_tag="KB913_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6820710.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            8293..8667
                     /locus_tag="KB913_002381"
     CDS             8293..8667
                     /locus_tag="KB913_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6820711.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            8677..9012
                     /locus_tag="KB913_002382"
     CDS             8677..9012
                     /locus_tag="KB913_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBB6820712.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            9095..10435
                     /locus_tag="KB913_002383"
     CDS             9095..10435
                     /locus_tag="KB913_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBB6820713.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            10513..11187
                     /locus_tag="KB913_002384"
     CDS             10513..11187
                     /locus_tag="KB913_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6820714.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            11180..11344
                     /locus_tag="KB913_002385"
     CDS             11180..11344
                     /locus_tag="KB913_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820715.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            11420..11854
                     /gene="dcm"
                     /locus_tag="KB913_002386"
     CDS             11420..11854
                     /gene="dcm"
                     /locus_tag="KB913_002386"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HBB6820716.1"
                     /translation="MRFLDLFAGIGGFRLGMEQASHHCIGFCEIDKFARRSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQRFSDTRGTLFFEIARF
                     TTLLRPKLLFLENVRGLLNHEGGATFETILRTLDGLGYDVEW"
     gene            11855..>12131
                     /locus_tag="KB913_002387"
     CDS             11855..>12131
                     /locus_tag="KB913_002387"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HBB6820717.1"
                     /translation="MLNSKAYIPQSRERIFLIGHSRDACTEQVFPIIGPSSTSDQNIR
                     NLVNINPSNRGMGGQVYGSDGVAPTLTGDEGIKIALPARDGISVAGLL"
BASE COUNT         3864 a         2254 c         2471 g         3542 t
ORIGIN      
        1 ctgcaatatt tatatcacag gcttttttct ctattaaata tatataagat aatacatttt
       61 tctactagtt ctcactaatc ttgtataatt aaaccctccg caacttgacg gagatggaga
      121 agatgccccc gtctaatcta gcggtcatct ctcctcccat tccttccacc aatttttttg
      181 acaggtaaag cccgattccg ctagattccg tatttgtgcg gctggtattt tcggtataaa
      241 aacgctggaa gactttttca acagaggttt gcgttcctgg tttgatagga ttggccactg
      301 ttaatcgaat gaatggatcc tcttttgaaa atgtcacctt tgcttgtcca tctgcataac
      361 gcaataaatt ctgtatgata ttttgcagca ctcgcagcaa catgagcgga tctgctaata
      421 cagttgtatt tatcgagtgt tcagcgaacg ctacctcgat atttttctca gaaaattgtt
      481 cataaaaaga gaaaaatact tcttccacct ctttagaaaa agaaagcgta tggagatcca
      541 tttctttttg cttcgtctct attcgagcaa gatcataaaa ctgatccgtc atactgagta
      601 atcttgcaac agattgtttg atgatcgtta aatacttctc ccgtttctcc gtatcctcta
      661 cctgttccag taattgtaca taaccgttaa tagcagtcaa aggagttctg agatcatgag
      721 aaaggccgac gatcgatagt ctgatgtttt cttccatttc ttgaaatgct tgtccttttt
      781 gttcattttc atccaaccat gtattcagtg catctactag gtccattaga ttcttttctc
      841 gaaattcgac tgaaagacga ccaccatatt cttgtcgttc agaaagagtg gcgattttct
      901 tagttaatct cttgatttcc ctttgcagga agaaaataaa acttcccata aagataacaa
      961 cgagaagcaa cagccattta atcaaatcta aaccccactc cccacaccgt atgaatatac
     1021 acagcatgtg cctttgctag cttccctcga agattggaaa tatgcatatt cactgttttc
     1081 tcactatcaa aatatggttc ttgccaaact gtttcataaa gatttgctcg cgaaaatact
     1141 tttttcggat gttctaaaaa aagcttcagc agatcgaatt ctcttcctgt caaatggaca
     1201 gccacaccat tcacatttac atccctcgac tctttgtcca gtaagatttc cttgtaatag
     1261 atgcgttgcg acagatcttt tacttggaca gaagtctgat gacgaagttg gatgccgatt
     1321 cgtaacaaaa gttcttcgat atcaaatggt ttcgtcacat agtcatccgc tcctgctgcc
     1381 aacaaggaaa ctttatctct ttgatcgctt tttgctgaaa gaacgatgat cggaacattc
     1441 gatgtctgtc ggatttctgc taacaatgct tcacctgaaa gccctggaag catgagatct
     1501 agaaggatca aatcgacagg atatgtgctt aacaataatt ttccttccgt acctgaataa
     1561 gcatcaagaa gtttgtatct ctgttcaaga acctcctcca gtaaggaatg aacagcttca
     1621 tcgtcttcga taatcaaaat agtttccagc aggaccacct acttaatgtc agatttttgg
     1681 aaaataaaca ttcctagagc tgatgatacc acgattgtta ctagactgac cagaatcatt
     1741 ttcggtgctt gcgaataagt tgcttgttgc gcaaagtccg tatacatgag ccacgtttcc
     1801 gtaaaccact ccgttagaaa ttccaagcct ttgatttttg cgaaaacacc gggaatgaag
     1861 gccgttccca tgatataaag aaaagaaaga agcaaactga cactggtact tctagtgatg
     1921 aatgtcaaag ccactggaac agataatgtc cctaatgtca gcagaagcaa tacaggaaat
     1981 acttttagaa cataatttcc atagtttttg attccctcaa cttcaccaaa tccgaaagca
     2041 agtgtgtaag caagcatggc tagtcccgtg atcaaaacca cgccaagtgt tgtgatcaaa
     2101 agcgtaacga gaagtttcga cacataataa gtcattcgat tccgtcctaa agataacgta
     2161 ttgcgaatcg taccgttttg aaattcttcc ccaatataaa agcacgcaaa tgctgcgaaa
     2221 gccagaagaa tccatgcagc cattttttct accattaaaa tccctgttgc accgttgatg
     2281 actgtatccg ttgcttggtt taattcattg ccgtattttg tatgcatata ccattcgttc
     2341 caagaataaa aaagcggaag tacgaccatc agtcctagtg agacccacat tttacggctc
     2401 ttccatactt ttattttttc agcagttaat agattaaaca tgtggattgc ctccagttaa
     2461 ttgtaagaaa taatcttcca gtttttgccc aactaggtga ataccatcca caggaacttt
     2521 tgcttctacc aatgcttgat tgatggctgc tacttggtca attccttcaa aaagctggat
     2581 aacacggcta gattgtacaa aataatccct ataaccaaga gagtcgagaa ccgttactgc
     2641 ttgttccgtc gccgaagtgt caatttttat aaattgacga gattcttgtg ccaattcttc
     2701 tttcgataat tctttgatca agtgtccttc atgcaaaata ccatagtgag tggcgatctg
     2761 tgacaattca tctagcaagt ggctagaaag caagacggtg atgccccgtt cttttaccaa
     2821 acgttggatg atttctcgca tttctgccat ccctgctgga tccatcccat tcgtcggttc
     2881 atccaaaatc aaaaattctg gattcgtgat cagtgcattt gcaatagcta aacgctggcg
     2941 catacctaaa gagaaattct ttgctttctt tttccctgta ttttccaatc gcatcatttt
     3001 cagcaggtct tcgatttctc tatccgacac accgccgttc gctgcttgga tacgtaggtt
     3061 atctcttgca gttaattctg gataaagagc aggggtttca atcgattgac ccatacgtcg
     3121 tcttgctgcc tgcaaatccg tcgttccaaa taattcgatc gaaccttcat caatcgagat
     3181 caaacccata atagttctca taaaggtaga cttacccgct ccattttccc caatcaatcc
     3241 atagatcatt ccacgtttga tttcgattga tactttatct aatgctttgg cagcaccgta
     3301 ttttttggtt ataccagttg ctttcaagac cgtttcattt ccaaaatcca tacttatcct
     3361 tctttcttat tgatgagtga agtatagttg acgggtataa agaaagcagc cagaaatgta
     3421 taaagaaagt gtaaattttc caattgaatg tcaaaaaaaa caatcggaca atacgtgtct
     3481 ttcctattat caggcagttt gttatacgct tgtatcagtt tcctgattct ttcttttcga
     3541 ccaaagtcgt ttctctgtat tcctcttcac tgaaaatttt tgcttctttc agatcaagct
     3601 tgagtaattt taccagaccg gttataagga taactatagc aagactccct cccagaaaaa
     3661 ttagactgtc tcgcagacgt ggttgcgttg tcttccaatc aaagagcgca ccaaacagtg
     3721 ctaatccaag tggactggcc accatggtaa tcgttgttat cgttgacata agtcgtcctt
     3781 gtatatgcgt tggaacttct cgctgaagcc agaccatata aaaagcaaaa gaaaacatta
     3841 atccttaaaa acggacttat gaaaaataat acatgccgtt tgggatttac aattagctac
     3901 caaataagag gttatgacaa aagacttttc acaatccctt cttccgaata aacggtgttc
     3961 tcctgccaac tcctcggtca caagtcacaa tatttatcaa acatgagaag caatttttgt
     4021 aaattccttc ttatttcttg aagctgacca cttctgtcac aacctcagaa gcggataaat
     4081 aatattgttt gatgatactt tatctttttc ccgtttgttt atagatcgaa tgatattata
     4141 gaccaagaat cctacctatt aacatagcta aaaacacaaa aaaggcactt tccaaattgt
     4201 ggaaagtgcc agaaaagtta ggattaaggt aactgcgctc agcattgctt cgcccagtac
     4261 gattctcgta actcgtgaac tcgaacgata atcgcaatta acgttttgag aactgtgaag
     4321 ctttacgggc tttcttaaga cctggttttt tcttcgtatc attgaataag tttgaaaaac
     4381 cttgatttat aaaggttttc ccgtaaatat attttattat atttgattaa atttgaaatg
     4441 tttgtgttct aaaatgtgtt ctaatttaaa ggcagtatat ttcgtatttt agattaaatt
     4501 tttaggctca ttcattctca aatccattct attcagtcaa taaaaatttt aaaaagactt
     4561 tataaacaaa gatgttcaag cgagcatctt atttttttgt gcttaatttg aaaggagaac
     4621 atttcatgta taaaaaacaa aaaaagaaat tatgtgtatt aactattttg agtttggctg
     4681 ttcaagcaat tgttggagca attgctccta cgattacttt tgctgatgaa attacccatc
     4741 cacaaacggt aaccgtagaa ctagatttag cacatcaata tgctgttgaa ggaactttta
     4801 gtgatggtcg tccaatgtca gaagtcactg ttccgcatta tgcagtgtac aacggcttta
     4861 aacaagatat tttctgtatt gaaccaggag tcccgattta caatgagttc actcctggct
     4921 atgagaaaaa cccgttacca gatatgtccg ataaagccaa attagtttcc gttttatgga
     4981 aaaaagtagg tacagatgca gatactcata ttgtggcaca gaagatgatc tggcaagaag
     5041 ttaatgggta tacccttcac tcaataaaac gatcagatgg tagtgccgta aatatcgcag
     5101 ccattgaggc aaaaataaat caagccattg acgattatca gaagaaacca accttccata
     5161 atagtacggc taaaacagta ttagggcaat cgactactgt gacggatacg aataatctga
     5221 atttgtcaga gttcgatgag gttgtggaaa atgccgcaaa cattgattat cgtgtgaatg
     5281 gtaatcagtt gataatcacc ccaaatgcca attcaaaaga aagtggtgtg ctgacgctta
     5341 agaaatctgc tggtaccgga acacctgtcg cctataaaaa ggctggccaa cagactttaa
     5401 tggccggggc gattgataaa cctaatacct acacaatcaa aattgatgtg gaaacggagg
     5461 gttctttaaa gatcaaaaaa gtcgataaag aatcgggtga tgttgtacca ggaacggttt
     5521 tccatttaga ctttggaaaa actttacctg caaaagacgt gactactgac aaagaaggca
     5581 ttgctacatt ggatgagatt cctcatggta caaaagtaac cattaccgaa aaatcagtac
     5641 cggcgcctta tacgattgat accaccccca tgactaccac cattaaagca ggcgaaacca
     5701 tttacgtgac ttcaaaaaac gcacgggaaa aagggcaaat cattctggat aaaagcggag
     5761 ttgaaacagg gagtgatctt tggaatgaca attattcctt agctggtaat acgtttgcca
     5821 ttcgcaaaga cagtccaacc ggtgaaatcg ttcaagaaat gaccacggat gaaaacggtc
     5881 atgcggaaac accaaaagag attgctaatg cgttggaatt gggaacctat tatgtgaccg
     5941 aaactaaagc tagtcatggg ttcgtgaata cgttcaaacc tgtaaaagtc gaattgaagt
     6001 atgccaatca aaccgtagcc cctgttacca gtaacgtaaa agggcaaaat caagaagtca
     6061 ctggcgaaac cactttgacg aaagaagaca aagatactgg ggataaagca caaggtaagg
     6121 cagtctttga gggtgctgaa tacaccttgt ttactgctaa ggatggaaaa gctgttaaat
     6181 ggagtgaggc ttttaaacca gagttagcga agggaacgaa aggttctgat gaaacggtca
     6241 ctttgacttt agacgaaaag aaccaagttg ccgttaaaca tttagctatc aacgagtatt
     6301 attggcaaga aacaaaagcg cccgaaggat atagccttga tgaaacaaag tatcctgtat
     6361 ccatcaaaaa ggtggatgat agcgaaaaaa atgccgtgat tacccgaaat gttacggcaa
     6421 aagaacaagt gattcgcttt ggctttgatt tctttaaatt tgctggatca gctgcgggca
     6481 ctaccgaaac tggcttcaat gatctgacct ttaaagtgtc gccattggaa gggaccaatg
     6541 aaatcacagg tgccgaagat gaagcgacca cagcttataa cgagcaatta gggtttgatg
     6601 gttatggcaa gtttgaaaat cttccttatg gggattattt acttgaagaa gtagaagccc
     6661 cagaaggttt tcaaaagatt acgccattag aaatccgttc tacttttaag gaaaacaaag
     6721 aagactttgt gaagagtgag tatgtcttta ccattaccga acaagaccaa aaacaaccaa
     6781 ttaaaacggt gaccgttcct tacgagaagc tgacgaacaa agcattttct gttagtttga
     6841 accgtttaat gctctatgat ttgcctgagg aagaagatag tttaacttct cttgcgactt
     6901 ggaaagacgg aaacaaagaa ttaacttctc tggattctac cgagctagtt gataaattga
     6961 gttacaatct acatgaaatc aaagaagact ggtatgtggt agcgcaagcc attgatgtgg
     7021 atgcgacaaa agctgcccaa gaaaaagatg aaaaagccaa accagtggtg attgcagaaa
     7081 caagcgcaac gttggcgaac aaagagaaaa caggaacttg gaaaattcag cataaattaa
     7141 ccgccgaaca agttttaaat aaaactattg tcttattcaa ctatgtgtat gaaaataagg
     7201 aagcttttga agcaggcgat aagccagtag cgaaggatgt tagcttgaat aaccaagccc
     7261 aaactgtcag ttgtacagtg gaacaccatg tttctatcca aacaaaggcc cacctagaaa
     7321 acggttctca gacctttact catggtgatg tggtggatat gtttgatgat gtgtcgatta
     7381 ctcatgatgt actggatggc tcaaaagaag ctttcgaaac aattctgtat gctttattac
     7441 cggatggtac aaacaaagaa atttggaaat ctggcaagat tgattatgaa gtaaatgata
     7501 aagaattcac caaaactgtg cttgcgaaaa aagtagatac cggaaaatat ccagaaggaa
     7561 ccaagtttac ttttgcggaa atcaattacg ataaagatgg gaatatcaat ggaaaacaca
     7621 atgaagattt gaaagaaaaa tctcaaacct taacaccaaa agaagttcca accatactaa
     7681 gtacgccgaa acaaccggaa acaccaactg ttccaagtgg ctctcaagaa tctagtccca
     7741 cagtgaagac cttccctcaa accggggaga aaaattccaa tgttttactg ttcattggtt
     7801 ttactttgat ttttgcgacg gcgggctatt atttctggaa tcgccggaac taaggtgatg
     7861 agatgataca agtaaatcct aagaaccaac gtgcgcgacc gcctcctaaa aaagtagtcg
     7921 cgctattttt gtatccaaaa ctaacaatga aaagaggaaa agaagatgga attgaaattt
     7981 gtcgtgccag atatggctga aacctttgga aagttaagtt atgccggtga aggagaaatt
     8041 ataacagaag gatatggacg gaatactacg gtgattggtc gcagttatca tttgtattcc
     8101 agtaagcaac gggccgatga tattgaggtg gtagtagctg cggaagccgg tgaaaaggat
     8161 tttgatcaag accaaccgct aaaagccgtg aatccccatt tggttgccaa aggctatgag
     8221 attgagaatc gtgggtttac tgattacgtg ttgtatgttg atgatttagt gaaagcatag
     8281 gaggaaaaga agatgagatt aacagaaggt attgtcgtag attcaggttt aacatttggg
     8341 aagttgcgtt tttccgcatt acgccgagaa gtacggaagc aaaatgagga tggaacaatt
     8401 ggtaatgagg taaaagaacg aacctataat ttaaaatcct ctgcacaagg gcgaatgatt
     8461 caagttagta tcccagctaa tgtaccctta cgcgagtttg cttatgatgc agaggtagag
     8521 ttggtcaatc caatcgtgga taccgttgcc aattatgttt ttcgagaagg aactaccgtt
     8581 aattggttca ttaaggcgga tgatttagtc ttgaagcggc agccgaatca aggaaatcct
     8641 acgaaccaaa atgaaagaaa gaaataggtg aagattatgg aaattaatgt tgaacatatt
     8701 ttagattgtc tcgatcaata tggaaaaggc gagctgactg aggaacaact cgttaaagca
     8761 ttaacctctg atgaaaaaat gtttctgatt atacatcaag gtttacttgg agaaaatagc
     8821 gacagtgaag aagactctga tgtactagac tggttaggag aagaagagtc tttctttata
     8881 gttgtcgaag taaatgaaaa cttatgtcgg caggcagaat ccattttgga agaaattggt
     8941 gtggagatgc cggatgctat tgaaggcttt ttaaatcaat tggttgaaac gaaacaactc
     9001 ccctcctcgt agcagtaaat gactagcata actttttgaa attgcctaat gaaatcctat
     9061 tgggcttttt cgattggagg tggaaaccat caaaatgtac aaaggacatc gcatacgcgc
     9121 aggagatcag cacttggttt atcactttgt tcttggctgg ctactcgctc tgttcatcgg
     9181 ttggatgagc gtcttttatt ttcaagagtt tagacaattt gatatttcta agctatcact
     9241 ttctactatt gaaatcgttt ggtctataaa agatttagta tgtctgcttg gaagtctcgc
     9301 tttttcagga gctatgatat tgctttatat tcactttttt cttgatcatt ggcgaagctt
     9361 gtggcatcga caaaagctag ctcggatgat tctagagaac cattggtatg aagtgaaaca
     9421 aactcaaagt gaaggctttt tcaaagattt gaatagtagc cgaaccagag agactatcag
     9481 ttacttcccc aaaatctgtt atcgaatgaa agatggatta ctgtctattc gcgttcaaat
     9541 ttcacttggg aaataccaag atcagctttt aaaattggaa aagaagttag aaagcggact
     9601 gtattgtgag ttagtagaaa aggaactcaa agactcctat gtggagtata ctttactgta
     9661 tgatatgatc gccaatcgaa ttgggataga cgaagtagtg gcagaaaatg ggactctgcg
     9721 attgatgaaa aatcaagtat gggcttatga ttctttaccc catatgttaa tcgctggtgg
     9781 cacgggtgga gggaagacct atttcctcct caccattatc gaagcactat tgaagtcaga
     9841 tgcagaattg tttatcctcg atcccaaaaa tgcagattta gctgatttag gtacggtgat
     9901 gcctcatgtt tattcacaaa aggaagaaat ttctgcttgt gtggaagatt tctatgaacg
     9961 tatgatggct cgtagcaagg caatgaaaga aatgtctaac tacaaaacag gagagaatta
    10021 tgcctatctt ggacttccac ccaacttttt aatctttgat gaatacgtgg cttatatgga
    10081 gatgttaacg acgaaagaaa gtgcggtgat tttgaataag ctcaaacaaa tcgtgatgtt
    10141 gggtcgtcaa tctggtttct ttctgatttt ggcttgccaa aggccggatg cgaaatattt
    10201 aggagacgga atccgcgatc aattcaactt tcgcgtggct ttgggtcgta tgagtgaact
    10261 cggatattcc atgatgtttg gggaggtcga aaaaaacttc tttatgaagc acatcaaagg
    10321 tcgaggttat gtggatacag gtggcagtgt gattagtgag ttttatacgc cacttgtacc
    10381 aaaagggtat gatttcttag attcaattag taaattagaa aagatgaatg attgagtgat
    10441 cttcaatact gactttatac ttcaagtaac gtataatact tttatatagt aggaagaaag
    10501 gggataatta atatggaaag taatgattct tatttagagt atgcaaaagc aaataaggat
    10561 aagtttattt cttatattat caaagggaaa tcccccgaag ttggacgaga cgcagttttt
    10621 atggcaggga gtcctggggc tggaaaatca gaggttgcca ttggattagc tgagaattat
    10681 gataaccatg tgattattga tgcggattac tttcgcaccc agtttcctga ttataatgga
    10741 aaaaactcta gtctctttca aaaagcatct tcttggttgg tagagcaggc atttagatat
    10801 gtcttagatc atggctattc ttttattctg gatgcaactt ttgcaatatt aagtgctgaa
    10861 aaaaatatct cgcgggcgtt gaaaaaacat tttcgagtga cgattttcta tgtttatcaa
    10921 gaccctaaaa tcgcttggaa atttacacaa gaacgtgaaa ttgcagaggg acgtcatgtg
    10981 ccgaaaaagg catttattaa cgcttttttc aaatcaagag agaacattgc aaaagtaaag
    11041 agtaaacatc cagatgtatt gcttcatatc ataataaaag attatacgaa taatatttcc
    11101 gaagttcatt atgctacgga taatctagaa ttatttttac cactagggta tagtaggaaa
    11161 gatttggagg ttcaattaca tgactgagaa agaacaagta acgaaaattg taaagaaata
    11221 caataagagc attgcggatt tatcggaaaa tgctactgca aaagagttca aaacggtgat
    11281 taaatatgta gccgatcagg ccaatgaaaa acaacggaaa ttagttggat taaataaaaa
    11341 atagtaggac aaattaataa tgtatgagcc aagagcaaaa tgttcttggc ttttttcttt
    11401 gcaatgaatg aggtaatgta tgagattttt agatttattc gccggtattg gtggctttcg
    11461 tttaggtatg gaacaggcga gccatcattg tatcggtttt tgtgaaattg ataaatttgc
    11521 tagacgtagt tataaagcaa ttcatgatac aagtaaggag gtggaaatgc atgacatcac
    11581 aagtgtatca gatgagttta ttcaatccct cggaccagtg gacatccttt gcggcggatt
    11641 tccgtgccaa gctttttcaa ttgcgggaaa gcggcaaaga ttttccgata ctcgaggtac
    11701 tttattcttt gaaatcgctc ggttcaccac tcttctccga cctaagcttt tattccttga
    11761 gaacgtccga ggattgctca atcacgaagg aggggctacg ttcgagacga tcctccgaac
    11821 gctggatgga ttggggtatg acgtggagtg gtaggtgctt aactcaaagg cctacattcc
    11881 ccaaagccgg gagcggatat tccttatcgg acattctcga gacgcatgta ccgaacaagt
    11941 atttcctatc attggaccgt cttcaacatc tgatcaaaac atcagaaatt tggtaaatat
    12001 caatccttcc aatcgaggaa tgggtggaca agtctatggt tcagatggcg tagcgccaac
    12061 cttaacaggt gatgaaggaa tcaaaatcgc actgccagca agggatggaa tctctgtagc
    12121 aggactatta c
//
LOCUS       DADVXE010000078        12014 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.080, whole genome shotgun sequence.
ACCESSION   DADVXE010000078 DADVXE010000000
VERSION     DADVXE010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.080"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(223..948)
                     /locus_tag="KB913_002388"
     CDS             complement(223..948)
                     /locus_tag="KB913_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820718.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(1102..1428)
                     /locus_tag="KB913_002389"
     CDS             complement(1102..1428)
                     /locus_tag="KB913_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820719.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(1465..1830)
                     /locus_tag="KB913_002390"
     CDS             complement(1465..1830)
                     /locus_tag="KB913_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBB6820720.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(1867..2082)
                     /locus_tag="KB913_002391"
     CDS             complement(1867..2082)
                     /locus_tag="KB913_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6820721.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            2211..2546
                     /locus_tag="KB913_002392"
     CDS             2211..2546
                     /locus_tag="KB913_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6820722.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(2622..4619)
                     /locus_tag="KB913_002393"
     CDS             complement(2622..4619)
                     /locus_tag="KB913_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820723.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(4717..4992)
                     /locus_tag="KB913_002394"
     CDS             complement(4717..4992)
                     /locus_tag="KB913_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820724.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            5224..5958
                     /locus_tag="KB913_002395"
     CDS             5224..5958
                     /locus_tag="KB913_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6820725.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            5997..7139
                     /locus_tag="KB913_002396"
     CDS             5997..7139
                     /locus_tag="KB913_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6820726.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(7767..8252)
                     /locus_tag="KB913_002397"
     CDS             complement(7767..8252)
                     /locus_tag="KB913_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HBB6820727.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(8254..9018)
                     /locus_tag="KB913_002398"
                     /pseudo
     CDS             complement(8254..9018)
                     /locus_tag="KB913_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9188..10381)
                     /locus_tag="KB913_002399"
     CDS             complement(9188..10381)
                     /locus_tag="KB913_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6820728.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(10465..10665)
                     /locus_tag="KB913_002400"
     CDS             complement(10465..10665)
                     /locus_tag="KB913_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBB6820729.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            complement(11089..11322)
                     /locus_tag="KB913_002401"
     CDS             complement(11089..11322)
                     /locus_tag="KB913_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820730.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(11329..11760)
                     /locus_tag="KB913_002402"
     CDS             complement(11329..11760)
                     /locus_tag="KB913_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6820731.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         3677 a         2465 c         1942 g         3930 t
ORIGIN      
        1 aaaatttttt cactaaaatc actacctgaa acagtctaaa acacttatat atcaacgttt
       61 aatgaaacta tctccgtttc atttcagata caaataaata tagtcgggct ccaaatccga
      121 aaaaaaatac ccccagtagc ttatcctaag ctactggaga tgtataagta cggtcatata
      181 acaacggggt agggtaaata aatgaaaaag atggaagaat cattattcaa taactttttt
      241 aaatacttcg ttgtaatcag ttacctgtcc gttcttaaat accacagaat aatctttttt
      301 cccattttca agtaaccgaa gtggaatatc tttaccaact ttctctgtca ctgcattact
      361 gatacctgtt agattagcta ataaatctga taaagattga gcatctgtag aaatctctgt
      421 atcagtattt atcgtgattc ctttatcttc atttacaagt ttccaagtag gtggtatagc
      481 tgtgtatgtt tctacaaatg aattaagttt ttcattaagt gacttctctt ttatatttcc
      541 atctaaaaac tctgtatata tggcttgagc tatactaaaa caaagctggc cttgttctaa
      601 taattttaca tcattagtta gtaaagctgt gttcacgtta tcaatcgctt caagaagagt
      661 atctttggtg tccctaacag ctttaggtgt gccttctgga atttccctac ttgatacctc
      721 gtccatttta tcttccataa accccttaaa atcatatctt tctcccaaat ccatagaagt
      781 ttttgagaaa gctttcattt ctgagtctat ttcttcaata atatttaaca tgtctgatac
      841 atattgttta ggctgattcg tttttaatct atatgtggta aatatctcaa ttcctccaat
      901 tatcaataaa attgccaaac aaatccataa taattttttc tttttcattt ttcctcctat
      961 acactgctgt tataacagtg actaatgtaa agattttccc agcaatcatc agactattat
     1021 ttacagggaa tcaaaaaaac tccttagtaa gcttacacct ttaggagttc ctgtttgaac
     1081 ggtatgcata atacatttaa atcaatttaa cattaacacc tcagtatatg gtatctctac
     1141 atatacacgg tctttttttg gatagtactc gacatttata ttgatagcac ttccattgtc
     1201 taacgtagct ttagcccggt acgtgttatc accattatca tgagtgatcg tcacatcatc
     1261 acatgtccga tttaagttat actgttcttg taaaatctga gttaccaatg gtacagatga
     1321 cttctctagt ccagatgaac ccgtcattct tgaaaaaatt atacctataa tagccaatac
     1381 aacgatacct ataatgacaa acttcttatt catatttact ttattcaact ttttatctcc
     1441 tatctccaaa atgattttct ctcatcagta actcattgac atccccaata gtacaccaaa
     1501 gatggctcca gctacccctg ctatcatcaa aatcgtaccc atttgttcat ctttctctcg
     1561 atataagtaa cccataataa cagcaacagc accaaatacc acaggaataa atgctaatga
     1621 tactaccata gaaatccaac caataatcaa atacagcttc cctgtctctt gtccatgtac
     1681 gatttgttcc ttcatttcat taattgtctg ctcagtactt ttctttactg tgtctgttcc
     1741 ggttgtctca tctgtttctt gtaatgctcc gcaaaactgg caatacttac tttcatttgt
     1801 tatttcttta ccacattttc tacaatacat gtcttctcct cctaaaatca ttcaattgct
     1861 tattagctaa ctgtttactt tattaaatac atcagaaaac agctcattta ttggtacact
     1921 taatatctca gaaagcattt tcatttgata gggtttagga atcgttctcc ctgtttgcca
     1981 cgaacttaca cattgctgtg taacattcat ttttttggct aactcagttt gggaaagtcc
     2041 tttttctttt ctgtatcggc tgagattact tacttttttc atgattctcc cctcctgttt
     2101 tattatatac aacaatatga tgtatttcaa ctcataaaat atataaatac ttcaaatgtc
     2161 attacaaata caacaacttg ttgtactcta ctgagaaggg gggtgtatta atgaaacaga
     2221 agcaatatgc aaaggtcatt agagaaaagc gaaaagcact cgggtggaca caaaaagaat
     2281 tagctaaaaa aatcttctct acacaacagg cagtagcaag atgggaaaat tctgtaacag
     2341 aacctaacct cgatagctta acagctcttt ctagagccct aggaacccct gtaagccatt
     2401 ttctagacaa tgttgacata gattatgagg aagagttttt ggctctctat cgctctctta
     2461 gtactgaaga tgcaattcga acaattgact atatgaagct attaaaaagg caagaaaatg
     2521 aacgcaatca gctattgaaa gattgaaaaa taaataaccc accgaacttt aacggtgggt
     2581 gtattgagat gaaataagat taagagctat ggataacctg tctagtttaa tataattggg
     2641 tctcttctat tccttactct ccgtccatca tctcttgtta cacttgtaaa ttgataaata
     2701 ggaactaatt caactcctga taatatcaat tcttttatta cttcatctat ccctgcccct
     2761 ttcgctagat atactaaaaa actactgctt gctttcacat tgtatagttt cttaatatcc
     2821 ttagaagctc gttcaagagt gaatccttgt ttaacaaagt agcctctgtt ttctattaaa
     2881 gcatttttca cgctgttatc cctgacattt cgtaggcgtt cacaaacagt gttaataagt
     2941 tctttttctg tcattagata tgtcccttgc cacgataagc cctgtaaaac ttcatgtgct
     3001 tcatctaaaa tcaattgttt ttccttgcta agttctgatc gggaattttg aggaaatact
     3061 cttttagcct ctttttcgtt aaaacatatc ttaacccatt cataagaaaa atattgatat
     3121 gtaaaatgaa atttttccag aagtggaagg atatcttcat tcaatttttg aatcacagaa
     3181 gttgcattaa aaacgtctaa tcgatagaca ttgcttctct tatgtttaaa gtttcctaac
     3241 gctttctctt cctttaacct atttaggtat tcgagcatct tcaaaggaac atcttcatca
     3301 tctaattttt ttatcaatcc tataaaagtc ataagtgata gtaacttatt acatttatct
     3361 atgtcataag ttttaccata gtaagaactc atttttttag ctaattgttc ccccgacaaa
     3421 atacaagtca cactttcctt actatcatca aaaaaattaa catcagaaag caagacatca
     3481 tagacacgtc gcatttcctc tagataattc cttattgtcc tgaaaagttt gtctttcatt
     3541 gattcaagag tgtcaaaaag tacttttgat tcctctttca attttcgaaa atgtgtagga
     3601 tacaagtcta ggttctctaa tagccaatta aatgtttcta cccgactgtc tttctttaaa
     3661 attagcatca caactccaat aaaattttca ctgatatcac aattactgga atgacaataa
     3721 aaaatggaat gcccagtttt actggtaaaa atactagcag agggattatg atcgttgtga
     3781 aacagacatc ttaagttttt acttgactta agtaatttat tcatatcaat ggttaacaat
     3841 ctttcataaa tctcattaaa agacatgtcg gaggaatcaa acaggcagtc tttaaaccac
     3901 tgtttcattt cttctttgtc gtcatttttt atcaacttaa caaaatcggt ttcattgact
     3961 agttcatact ctctccctga atcactttga caatttttag aacatgtcat ggtaaaatca
     4021 atcggaagct cagtaatatc taacatgttg tcttcattaa ttattatcac tgcatctgac
     4081 ttatatcctc caaaaaacat tctattcgaa gcatttacat tgtcatcaca cccggggatg
     4141 ttctttttca agtattcgta aacagcaacc attttaccat agtcagtaat tgcttctttt
     4201 aatagaaaga caatcttgta tttttctaga ttttcagagt accgaatact tttttgtatc
     4261 gcaaacgcag aattatgaac taaattgata gataaaacct tttctatgct taagtatcta
     4321 ctatcatctt tactcaaatc tactaccttc cccttctcat ctttaacagt gttatcgaca
     4381 tccagaataa ttactctggt ttccacaaaa ctctccttgt cattgccttt attctttgtc
     4441 ttgcttggaa taaatgattg tgatgaattt agtatctcta caaactcatc tcttgtaact
     4501 tctctatagt tatctaaaca cctatctctt acatcagttt tttctttttt tgtaactggc
     4561 ttctctaata atttttcttt atctacataa attggaatat taatcattga tgtttccatt
     4621 tgtgtttcct ccttataaaa ttctgttaaa gactaaaaca tacagataat aaaaacaaac
     4681 tctttattac tatatgtttt agtcttattt gtttactcaa cctttatacc gttccatgaa
     4741 actatcaata tcagattttt taaatctaat gaccgtatca atttttataa caggtaaccc
     4801 gtattgagaa acatattttc taatcgttcc tactgataca cctagatatt cacttgcctg
     4861 ctgatagtcc atatactcta gagtgactcc agaaataatg tcttctagca taggctttag
     4921 cactgtaatt atctctttca cttgttgttc aacttgtata gaaacaatgc tatcaatgat
     4981 ttgtagagac atatttcccc ctcctttcgt gattgcttga acaaattttc taagaattat
     5041 cttcgtattt tttgctcaaa ataaaagtat tttgttatta accgattaat caaacaaaaa
     5101 atgattacca gttcatcgac atacacataa tacctcgata aaaaaggggt gtcaatagtt
     5161 ttgtaaaatt tatttacaac accccttttt tgaggtatac taattttagg aggtgtggtc
     5221 aatatgataa aacgtccacc aataaattat ttagaacgaa aaaagatact cggaacaaaa
     5281 ataaaagcta taagaaagag taaaaaatta acacaaccag catttggtct tatgattaac
     5341 aacggtcaat taattgacaa aaagactatc tacgaatggg agaagggaac ctatttacca
     5401 ataccagagc gattatcccg aattgctgat ttgggaaata tgagtataga ggagttagtt
     5461 tgtggcaatg tagaagaata tattttggga attattcttt atagagatag cattgtacta
     5521 gatggtataa catttccaga taaaaacctg ttccagcatc ttcgtcaaca gttcccacca
     5581 gtacactcta atttagatac atggctggat agatattcca aattagaacc agagatgcaa
     5641 gaatttattg ctaacaagac ttgtaataaa gttaaaaatg aaaaaattag tcttttcaat
     5701 atcttaaaaa tagaagaatt attcatcaat gctattgtag aagaatttga caataacatt
     5761 cttttcctca ctagcagtat agaagaacta ctagaaagaa tggtagatga atggctacct
     5821 attcaattga aagacatgtc ttatcccgaa gaagctgtga gagaaattac tgataatata
     5881 aacaagctag aacaaacgat ttcatcaatt gggaaaaaat acactaagaa aaaaatgaag
     5941 ggaggtgata ccatctagtg gtaagtactc cttgtaaact aagaggagat gatttcatgg
     6001 caaaaatatc aaagtacaaa aagaaaaacg gtcaagtggc gtggatgtat aaaggacaca
     6061 ttgccaccga tccacgaact ggtgaaaaaa taaatactac gagaagaggt tttagtagca
     6121 aacaagaagc tcaaaaagat tatgacgagt acagacatca aatattatac ggtgttaaaa
     6181 agaaagcacc tgatatgaca tttgaagacc tgtataatga atggataact catcagcgta
     6241 ccagtgttaa agcttcaaca atcgcaatct cagtaagata cgcaaataat caaatacttc
     6301 cagcatttgg taagcttaaa ctatcgaata tctctgtccc atattgtcaa aaagtggtag
     6361 atgaatggca cagtaaatat gaaagttacg attatatgag aaaacagact gcacaaattt
     6421 tacgctacgg ggttgcaatg caatatattg acaataatcc tatggaaaaa acacttcttc
     6481 cacgaaaaaa agagtatgag aaaaatcgta aattttactc aaaagaggag cttaataatt
     6541 tactggatgc ttttaaagat tttggtaaca tgaaacaata cgccttcttc agattattgg
     6601 catacacagg tatgagaaag agtgaagtac tcgctttaca gtggaaagac atagacacgt
     6661 ttaataaaga actacatgtc aataaaactc ttgctgtaga tgaatttggt aaagttataa
     6721 ttcaatctcc gaaaacaaga gcttctagac gagttatctc tttagatact gagactcttt
     6781 ctatcctcaa caactggaaa ttacagcaaa aagaagagta tttaaaactt ggatacaata
     6841 ctagctctaa agagcaacat gtttttacaa cagttaaaaa cactctatac attccaaaca
     6901 ctgttaatga ttggttaaga tatattttga aaaaatataa cttgcctcgt attacacctc
     6961 atgggtttag acatacacat gctagtttat tattagaagc aggagaatct gtcaaggtag
     7021 ttcaacaacg attagggcat gaaaatagta aagtgacatt agacatctat gcacatatta
     7081 caaataatgc acctaagaaa acaggtcaag actttgctga tatgatggct catcagtaaa
     7141 agagctggtc aaaatctggt catttctagt atacaggcaa aacaaaaaag ctagaaccct
     7201 tatatatcaa gggttctagc tcctataaca ggtttaccca acactgcctt ccaatgactc
     7261 ttttgggaat cagaggaaag aatcaggctt tatagagata tttcatctaa caaattactt
     7321 tagactgaca gtatatatca gcaggtactg tcatcgggaa cgtagccaat atcgtatcca
     7381 aaacagcagg tagagaagct atttgaggat tcaagttatt ctatttcaac catgaagtta
     7441 agttcattaa aaataaagat agttggtatt tcaataattt ttgtatagag ttaatcactt
     7501 tattgatgct aattcatctt gattggtatt ataatcgtat tcaagttgcg tggcgtgctt
     7561 ttgctagaaa atatataact gttctttata aagaaatata aggattaaac attttttatc
     7621 atagagtttt acttatctat agaattatgt ctgttcctaa ttcagtttga tgaattaact
     7681 gataaaaaaa tatctactat ttaaagatac agggataagt aagtaaaaaa ataacatgtc
     7741 attagatagt agacagttcc aactctttat ttaccttttt tgtatgctgc actgtcaatc
     7801 caagttccta aattgttgta tccatcatca cttatataat catattggcc atcaataatt
     7861 tcgtcaaacc acaaatattc tccatctggt ttttgcccaa ttattttaat tactgattga
     7921 ctagtagttg tcatctggtt aaaatctttt attttaccta tattaacggc caaaatagca
     7981 tttcctcgct tataactctc ctggatttca tatttaacat attctcgatc aagagtttct
     8041 ttacctatca gcaccacagt cactgatgtt ccaattaatt gattatctat ccagtttttt
     8101 atagcaatat ctccattacg tttaactttc tcaaattcag ccttatctac aaaaccagct
     8161 tcctttgttc ctcgcaaagt ccagctgttt ctaactacca ttgctcttgt tacatctgca
     8221 taatggaaac taaaaaaaac ccttctcacc atattaatcc tcctgaatac tatttattaa
     8281 actgacaatt tgttcaactt ttttatctac ttctccttca gtatctaatt tttctagcgc
     8341 ttgaaattta ctttttaagg aatcatcaaa ataatcactg aaattctctt gaatcttatc
     8401 aaacaaaacc ttacttgcac ctttggtaaa tccaatcgga actactatat tttcattttg
     8461 aacagataat tcaaattctt caatcattcc atctgctgta actatttcac ctgattcaag
     8521 tttgtttcca aaaacaaaaa tactaatccc agactctgca ataatgtttt ctcgatatct
     8581 tctccactca tgaggcatat caaggggaag tggtcttaaa gaaagtacgt cttgtatgtt
     8641 attttttctt aaatttcttc tctgctttag aactcctgaa acaatactat taccaattcc
     8701 aagtccgtaa cctgatacta ttctataacc ggattcagaa agcctatatg ctaatttctc
     8761 gacaaatttt aatcctttcg attcagatgt aaatggagta taatcaacag cacttcccga
     8821 aataaaaata gtttttctca aatacttttt tctaatactt ttcaaaatat cagtaatctc
     8881 agaataatca tctacttcaa caacgtttat cgaaaatctg gacaaatcat tgatttgtag
     8941 tcttcttttt gtcagttcat aattatatct ctcttgatca aaaaaatcct cagaatcgac
     9001 aaaattttcc tttaaaatta tatgggattt tagattatct ttttagaagt tcttgaatgt
     9061 cggtatagcc cgtgtttccg ggcttttccg gcatttttga tattgttaga tacttacaaa
     9121 tgttcttatt acctctcacc atttccccct caaaagtagt aaatggagta gtaaaaccgg
     9181 ccttgtgtca ggctgccagc cgttccattt ctgcccttgc ggaatcgaat gtggcgtgtg
     9241 cataatagtt cagcgtcatg gtgatattgg aatgtcccat aatgtactgc aaggctttgg
     9301 ggttcattcc cgcattggct aaccgggtgc agaatgtatg acgcatagca tggggcgtcg
     9361 tcgttttcgg caacgcttct tcatggctct tgttgtactt cttcacaagc ctgccaaaca
     9421 tcccgccata atctaccgcc gtcatgggat agccgttctg tttgagaaac aggaaattgg
     9481 catacccgtc aataatgaac ggctttgcac ctttgcggtt ttttatcact cgctggaacg
     9541 cctgatacac ttcctcattc atggggattt ttctgacgcc gctttgggtc ttgggttcgt
     9601 caatatagta accgacgccg gtatttctca aaagctggtg gctcacgatg attacccggt
     9661 tttcaaaatc caaatctttg tccgtcagtc cgcacagttc cgaaatgcga agccctgtcc
     9721 ccagcagaat aacgattgcg tcataatgct tttggtaaac cttatcacct tgaataaagg
     9781 acagaaaact ttcttcctgt gctggtgtaa gaggcacctt tggttccgta tcgtcgtcca
     9841 gaacgtcact aagctggaag tcaaacgggt tttttcggat gcaatcgtcc tgtatggcgg
     9901 tgtaaaaagc cgctttcagg gaacgcttgt cgttattgat ggtcttataa gaaaggccct
     9961 tttctttcat ccgaagcgcc cattcctttg cgtcggacag cttcacactg tcaatcgggc
    10021 agctccccag ccgatcttgt tccagaatac gcatcagccg ttcccggccc agtttggtgt
    10081 tgtgcttcac attgccccgg tgcctgatct gcttggcgta gagctggcag acggtcattt
    10141 tcttgccgat ggtgtctatc ccgtcgtcaa ggtctttctg gatttctttc tccttttccc
    10201 ggagtgaaat atcctcccgt ttacctgccg gggtcttatc cgtaggcact aacttccatg
    10261 agtaaacaaa ctgcggtttt ccaaaggtat caacatattt gtaagcatat cgtccgtctt
    10321 ttctctggct ctctccagac cgcaaaacgc gatttttgct gtctcgtctt ttttctgaca
    10381 tctcgtcatg ctcctttcca tgacggaaag agccgcatat atgcttataa attattataa
    10441 catatctgcg gccctttttc actattagat tgtgtccaaa gtgtcaatta ttttctcaaa
    10501 ctgcttgcgt ttgatctgga tgcggttgcc attcataatg acccagccag aggccggatt
    10561 ttcctcggcc agcttacgca atttgttttc tccgatacgg aaatatttag acgcttcctc
    10621 aatcgtcagc gtgtattttt cccaaatagg cacatcatgg ttcataatgc agcccccttt
    10681 cacaaattca aaggtttgtg tgatttaggg gcatagacgg acggctgctg gcacagctcc
    10741 acgggacttt cacccccgcg tggttctcac gcggccctac ccattgcctg cgacgctttt
    10801 aacgctcgga ctgtggctat aagggagtat catagtcctg cctgtacgtc gtcgcccgca
    10861 agccgccacg ctcacattgc ggcgtggtgt tcctcgctcc gcttttcccg tagggaaaag
    10921 tatcatggcg caccagccgt ccggctcggc acagacagaa tgtgtccgta tgccctatga
    10981 tgcgccgccg ttatcttgcg ggcatattta tcaaggtgcg atcaggccac cgggaaaaca
    11041 ccgaaacggg gaaagggtaa gccgtttcat gctgccgggg ccggttcgtc agttcgtgac
    11101 gatagcgtgg atgagcttga tttccagacg gcgcttcatg gcctcgtcca gacacacatg
    11161 cggatagccg ttttcgtcat agagcgtccg ggtacacagc ttgttcatgt aaccgctgta
    11221 atactgcaaa acgcgctcta cggctccggc atccccagcg cgggcggcct cgatcaccga
    11281 aaggggcaaa agctcaatgc ccttgtagtt cgggttcttc atccgcgtct aacctccctt
    11341 cggcatcaac gcctttagct gtttccgcag ctccgataag gtatttgtcc tgtgccgctg
    11401 aacggcactc cgggacattc ccacaaggcc gccgatctca ccatctgcca tatccagaac
    11461 acagtgcagg attaaaatac tctgctccat gctgggcagc gcggcaaagg cttcggcaac
    11521 aagctcattg ttgatatgta ggtcatagcc atgcgacgaa aacgtaaagc tgtcgctggg
    11581 gtagtgatct actgtacaga gcttgtccaa atctgcctgt gacaaagagc ttagtgacac
    11641 ttcacggtca cggcggcgct tcatttcagc caagtagctt ttggcctcgt tacgcagtac
    11701 cgtcttgcaa aaagcatcga acatgcaccg cgcttcatag tcgcggggga tagcatccat
    11761 cttctcaccc cctttctgtg ggggacttag gtggttctct ccctttccgc taacaagact
    11821 ttgacaaggc cgccagctac ccgctaaata cctccttttt gaaaatttct caaaaaattt
    11881 ttttggggac agccgggccg caaaagacga caaaaatcgc ccggcaggtc gcaaacctac
    11941 cgggcgagaa aatgctttgc tatgctgctg atttacatgg tatagtacat actcataacc
    12001 ggaatagccc tgtg
//
LOCUS       DADVXE010000079        11837 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.081, whole genome shotgun sequence.
ACCESSION   DADVXE010000079 DADVXE010000000
VERSION     DADVXE010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11837
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.081"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..177
                     /locus_tag="KB913_002403"
     CDS             <1..177
                     /locus_tag="KB913_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6820732.1"
                     /translation="YLLGMALAYSVGSLIKVNVSLDLFTILLAVGVSSVIGLVFSVMP
                     ASEAAKKDLIDILR"
     gene            578..1183
                     /locus_tag="KB913_002404"
     CDS             578..1183
                     /locus_tag="KB913_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HBB6820733.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1199..1771
                     /locus_tag="KB913_002405"
     CDS             1199..1771
                     /locus_tag="KB913_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6820734.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2023..2280)
                     /locus_tag="KB913_002406"
     CDS             complement(2023..2280)
                     /locus_tag="KB913_002406"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820735.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2406..3221)
                     /locus_tag="KB913_002407"
     CDS             complement(2406..3221)
                     /locus_tag="KB913_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820736.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            3738..5063
                     /locus_tag="KB913_002408"
     CDS             3738..5063
                     /locus_tag="KB913_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBB6820737.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5056..5406
                     /locus_tag="KB913_002409"
     CDS             5056..5406
                     /locus_tag="KB913_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820738.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            5388..5573
                     /locus_tag="KB913_002410"
     CDS             5388..5573
                     /locus_tag="KB913_002410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820739.1"
                     /translation="MGSIRMNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSF
                     YVEAAAGYHKYEYYIGY"
     gene            complement(6477..6752)
                     /locus_tag="KB913_002411"
     CDS             complement(6477..6752)
                     /locus_tag="KB913_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HBB6820740.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(6724..7677)
                     /locus_tag="KB913_002412"
     CDS             complement(6724..7677)
                     /locus_tag="KB913_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6820741.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            8289..9782
                     /locus_tag="KB913_002413"
     CDS             8289..9782
                     /locus_tag="KB913_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBB6820742.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            9917..10213
                     /locus_tag="KB913_002414"
     CDS             9917..10213
                     /locus_tag="KB913_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBB6820743.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            10314..11165
                     /locus_tag="KB913_002415"
     CDS             10314..11165
                     /locus_tag="KB913_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820744.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11186..11469
                     /locus_tag="KB913_002416"
                     /pseudo
     CDS             11186..11469
                     /locus_tag="KB913_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         4075 a         1820 c         2197 g         3745 t
ORIGIN      
        1 tatttattag gaatggctct tgcttatagt gttggttctt tgataaaggt aaacgtgtca
       61 cttgatctat ttactatttt actagcggtt ggggtatctt cggttattgg actggtcttt
      121 tctgtaatgc ccgcttcaga ggctgcaaaa aaagatttaa ttgatattct tagataaaat
      181 cagaatgaca agaatattta cgttctagat tctaaaataa aacacaaaga gaccaaccag
      241 gcaccctatt gtttctttgt agtatagaga tattctttgg cttgtaagag atcaatagag
      301 ttaggtgacc ggagttcgaa ataaaggaaa tttttgattg tataggagaa ttctttatcc
      361 ctaatattta gaattttgag tatgccatgt tgatgtttta gattctctat aaatatagag
      421 gtgtatcaaa ggtcaactag actgtgcaaa atagagacac ttgaaaaatc tatcgggggt
      481 cagaaactta atagtttttg acacataaac aaaatcgcga tataatgggg ttgagagtgt
      541 ttcataaact tatgtcataa agttaaggag atttcgcatg attttagaga ataaattggg
      601 attaaccaat caagttgagt tggctaaggt tgaagaaaaa ctcagtaaac aaaaagcgaa
      661 agaattgtac gattgtggaa aaataaatga aatcgaagtt ggtacattta aaggtttatc
      721 tgaaattcat gaatttctat tttcggatat ttacgatttt gccggaaaaa tccgatcggt
      781 caatattgca aaaggaaatt ttcgatttgc accagttatg tatttagaac attcgttaca
      841 gcatattgat cagatgccac aaacttcttt tgaagagatt atcaagaaat atgtggagat
      901 gaatatcgct cacccatttc gagaaggaaa tggccgaagt actagaattt ggctggatct
      961 cattttaaag gaagaattgc aaaaagttgt agattggaac ttaatcgata aagcagacta
     1021 tctttctgca atggagcgaa gtcccataaa cgatttggaa atacgctatc taatttccaa
     1081 tgctctgact gataaaattg acgatcgcga gttatatatg aaaggaatcg atgtcagcta
     1141 tttctatgaa gggtattctg agtatacgat agatgatttg taaaagtagg tggaccaaat
     1201 gacgaaatat ggatatgcac gtgtctcaac cgcttctcaa agtacaaaag aacaaattca
     1261 acagttgctt gagaacggcg tagagaagaa gaatattttt tcagaaaaat ttacgggtac
     1321 aaaacgggat cggccaaaat tcaatcagct gttggctggt ctgaagcctg gagatgaaat
     1381 agttgttacg aagcttgatc gatttgctcg taacacgaga gaagcattag agatcattga
     1441 acctttactc gatgataacg taacgatcaa ggttttgaat ctaggaacga ttgaaaatac
     1501 gtccatgggg cgaatggtga cacggacgtt gttgagtgta gcagaaatgg aacgtgatat
     1561 gattgtggaa cgtacccaag aaggaaaaat gtttgcaaga aagaataatc ctaatttcag
     1621 agaaggacgt ccgaaagcaa caatcacacc gaagaagagg cacgcatatg aactgcttac
     1681 ttcaggtaaa tcgtataagg aagttgaagc tataaccggt ttcagtcgca gtacgctttt
     1741 tagaataaag aagaaaattg aagaaagtta aaaaagaagt ctcagcgaac cagacaggta
     1801 aatacttaat gcgttctaga tatgagtcta ttagcatgtt gtgaaatata atattttttt
     1861 atttacttga tttctgctca aaaaatgtgt atggtaactg taaaaggtaa agtaattaaa
     1921 ggtatgctag ccacgcttac tatattagga taccatcata tatttataat gaacgatttg
     1981 ttcgtctacc aaacaacaca tatcgttcag cgtaagtcac gtttaggaac gtggcttttt
     2041 tagtgttatt atcgataaat aatctattga ctctattgat tttatctcca tatccctacg
     2101 gtgttgattg tctttagatc tttcatttaa gaaccaaata actatcataa aaatcagcac
     2161 tgctgctaat ataataaaca gcattcctat tgtgatatta cctattgatt ttaccataac
     2221 tacgattaaa gtaataatgg cattcaagtc tcctttgttc tctatatata aattagccat
     2281 aaatcatctt cctttcaaat taagatactt gtttgatacc aataaatagt aagcgtggct
     2341 agcatacctt tttctgtaat agcaagtgtt ctaatagtcc aaacttaatg atggaccgat
     2401 gctagttata gtacagtaat gttttctttc ttatctagat ttttagtaag ctctatcagc
     2461 aaatctaaca aatctgagtc cttttcagaa actaaattaa atctagtgtt tacaacaaag
     2521 ttttcatgtt ctatattgtt tagattattt gcggaaagga gggcttctag atcttgacat
     2581 tcaaatctat atgcatcgtc ataaatctta ctagaaggag tgcttaattc gaaattactt
     2641 attttctcat cttggaccaa gataaattta tagatagtat ctttttgtgt ttttctttta
     2701 aaaacacaac agagtgtgtt ataaggaacg ttataatttt catcagcctc attttttctc
     2761 cattcaaaca aatgataaac tgcaaccaag ttgccatcaa tttcatggac agtgctctcg
     2821 gtaacatcct ttaaagaact atcaagggct aatttatagt aactagagag aggaagtaaa
     2881 attgtcgatt tactgagatg gttatcgtct atacgtgcaa tcatacctaa atcaactaag
     2941 gttttattcc aggtgtttat agttttagtt gtcactccta gagactctgc tatggtattg
     3001 accgaatgcc aggaatcccc gccttcattc tttgccttaa aacagtaata cagatataaa
     3061 ttaatagctt tgttattcgg taaatatttt tcaagttctg ttggtagaat aaagtaagaa
     3121 tccttaatgt tttttctgaa ctgtctccag tctctgtagt tttgtttata aagttgtgaa
     3181 acggtttttc cacctttaga aagtcctgct atcttaacca atcttattgc tcctttcttg
     3241 aatctgtcat gatcatacag tattttttac ttgtagtcca gcaccttaat atattatcct
     3301 atgtaattaa tttcgtacta gatagtaatt attttttatt taattctcta gtcacttaca
     3361 aataagttat ataaactacg attaataaat tattacaaaa actattaaga aaacttctac
     3421 atacaactat tacaaaacta ttaagaaact gaatactcct attttttgtt tttaaggaaa
     3481 gttttttctt ttttgaattt cttatttttt tctaatataa ctaagcaaaa ctggataata
     3541 cgacacttat tttcaaattt tcacaagact aatagtaaat atccatttaa taaagtgata
     3601 caatgtgttg attttacaaa tcaacagaag aagtagggaa ataacttacc tatgcttctt
     3661 tttttgtaca tttaatcgat tcttctttac aaaaacgaac gtatgtttgt ataatgtgga
     3721 agaatggagt gttatttatg atggattatt caaaagagcc agtaaatgat tactttttga
     3781 tcgatatgaa aagcttttac gcaagtgtcg aatgtataga aaggaattta gatccattaa
     3841 cgactgaatt agtcgtcatg agtcgagcgg ataatacagg atcagggttg attttagctt
     3901 cttcaccagc tgcaaagaag aagtacggta tttctaatgt cagtcgacca cgagatctac
     3961 cgcaaccttt tcctaaaacg ttacatgtcg ttccaccacg catgaatctc tatattaagc
     4021 gaaatatgca ggtaaacaat attttcagaa ggtatgtagc agacgaagat ttattgattt
     4081 actcgatcga tgaatcgatc ttaaaagtga ccagatcaat gaatcttttt acgactgaag
     4141 gaacaagaag tcaacggaga aagaagctgg ctcaaatgat ccaggagaat attaaagaag
     4201 agctaggatt gcttgctaca gtaggtgtcg gagataatcc cttattagct aaacttgctt
     4261 tagacaatga agcaaaacat aatgatggat tccttgctga atggacgtat caaaatgttc
     4321 ctgataaagt atggaatatt cctgaaatga cagacctttg gggtattgga tctcgaatga
     4381 aaaaaagact caaccaaatt ggtatcatga gtattaaaga cttagctaat tggaatccat
     4441 acactattaa gagccattta ggtgtgattg gcttacagct gtattttcat gcgaacggga
     4501 tcgatcgaac agatatagcg atcccaccag aaccgacaaa ggaaaaatca tatggtaatt
     4561 cacaagtgtt accacgagat tataccagga gaaatgaaat cgaactggtg gtaaaagaaa
     4621 tggcggaaca agtagctatt cgtatcaggc aacataactg taaaacaggt tgtgtccatt
     4681 tatacattgg cacgtcgatc ttagaaacga gaccaggttt ttcacaccag atgaagatcc
     4741 ctataacaga taatacaaag gaattgcaga attactgtct tttcttgttt gataagtatt
     4801 atgaaggaca agaagtaagg cacgttggaa taacctatag caagcttgtg tacactgatt
     4861 cgcttcagct ggatttattt agtgatccac aaaagcaaat tgacgaagaa aatttagata
     4921 aaattattga caagattcgg caaaaatatg gttttacgtc gattgtacat gcttcttcta
     4981 tgttagaagg cgctcgtagt attactagaa gtacattggt tggtggccat gcaggcggcg
     5041 caggagggct taaaaatgat tgattataat gatcgtggac gtttaaagtg ggcaggtttt
     5101 tatttatctg atcatactga aaaaattgat gccgacaatg aacaacgagc caatcaaaat
     5161 ttggcaaaag aacaaatgac gactgaagag gttgcggaag tattgaacgc tgcagtcata
     5221 aaaaatagat cagtatgtat tcaaaaagaa gaacgaaacg ctgaaggata ctatccagaa
     5281 gatattgtta gcaagatctt aggtagtgat gagctgggga tctacgttgg aaaaaacaaa
     5341 gttcactacg acgaaatacg tcatatcgaa ttttaccagg ataataaatg gggtcgatta
     5401 gaatgaacat tatccagcaa tatgagctaa agtatataac ctttgatcag ctatcagaag
     5461 agatttgggg ttatggccag cgtttgataa atgaggttgg tgttgaacgc ttctctttct
     5521 atgtagaagc tgcagcagga taccataaat acgaatacta tattggctat taaagtgcaa
     5581 taaaattata tttcttttat gttttacatt ttgtatcaat tctgataaaa ttacctatag
     5641 gtaattaaaa aatataaaaa aactagttac aaccttagga cgttgtaact agcttgaagc
     5701 atactagagc taactaaaat agcactagaa agcaatgtta aacccgtcca acaaacttga
     5761 tttaacattg agaccagctt attcagctaa atatagttga ataagcttct tttgttttaa
     5821 aaaaacaaaa ggtgtactac gaataacgca agtaaaagaa atactattac aaccagtagg
     5881 ctacaagtaa gtattactaa acattgcgta gttagaacct ttgctctatt gtctaaagcc
     5941 acaaaattag agatcagctt tatgatgcta agagcgagct gcatccatgc ggacataggt
     6001 tcttttgaca ctattaattc tcctttttag gataagggaa attgctagta gttttttcat
     6061 tagcaccatc ccccttcatt tgattgagtc tagtgctgct gtgatagttt gctgtttaat
     6121 atgcttacat tcttattata acataaatga aacaaacaca tggttagagg tcgtatcaat
     6181 caaaatagtg tctcacaaac gatttattac ttactcctgc tgactaacgg actgttcttc
     6241 agtaactgta actatatgtt tgttaaaacc accattacct gtagataaaa accaatatat
     6301 ttactatact cactatatta aatatattta gtatagtaaa aactagaaac aataaaattt
     6361 gtgaatgttg tataccccca aacaatacac atattttgaa ggattaggat taataaagct
     6421 aaaaatatag taagtatact aaatatattt actatatcta gtatacttac tatattttaa
     6481 tcttttgatc gtctattata tataatccgt tcctcgtcgt ttaaagtatc aacataggcg
     6541 tccattgcaa gtttgactat ttcatacata ggaatatctt ttgcataact aagatcccga
     6601 atggttttta gtacgggagg atctacttga actggttttc tttctttcgc agtgtacttt
     6661 cgttccccta actcgacatt aatatcatct ttaattgaaa tatcttcagc accaattttc
     6721 ttcttatctt tgttcgttgg taataatgcc atttagttta atctcctttc caagaggtag
     6781 gatatgattg gccattgagt cagcatattt aggtgtataa tcaaatcctt caatatcacc
     6841 atgttgttca tagtattcaa ttctttcttc taattctgta aagatgtctg caaaaatagc
     6901 ccaccatctt cgatctacat aatcatttaa ttggatacca ttctcaccat acatttctaa
     6961 ccgatccgag cctttaacaa tgcttttaaa aatgtttgat tcaccatact tatcaattgt
     7021 tttttgatag tttgcgtgtt gagaggaacg tcgcactgag aaaagaacag gcaaaattcc
     7081 aatgatttga agatgagact cttcaaaatt cgtgacaatc ggaactaaaa ctttattaat
     7141 aaaatcttct gttccttcca ttgcgtaccg ttttaattct tgcattgcaa taatataatc
     7201 tgcagcagtt aagaatgcac gaaccacatt atctgttgat ggtgggcagt cgataaagat
     7261 ataatcgaaa ttttttctca attcttctaa aggtttaatg aaggccaatg atctcttacg
     7321 acgatcagga tatttttcgg acaagtattc attaagttct tcagatccag gagagccagc
     7381 cataatatat aaatgtggac ttacttgagt aatacctgaa acccagtccc cttttttgat
     7441 tgctgcagac atggatcgat caaagctagt aatttgatac gttgatccaa tgttggaagt
     7501 agtatttctt tgttggtcat aatcaattag caacacgtct ttttcaaaaa gttgactaga
     7561 aacaatcgct aataaatcat tgtctgtagt cttaccaatg ccgccttttc tacctgtaag
     7621 cattacaact tttcctagtt tatctgatgt tttaaatgca gtccgtaagt tttccatagt
     7681 tccctccaat ttcctatact aaatatattt agtatacttc atatacttaa tatattcgat
     7741 atatctaata tactccaaat tgataagaat tcagacttta taaggaatat agtggatata
     7801 ctaaatatat ttgctatatt cagtatatca gatatattca aaatgtcaaa atatatttgt
     7861 gcgttttgcg ttgacaattt agagtgaaaa gaggtaaact taattctata gaaaccacag
     7921 ataattcact atttacaaag tagcaaaagc agtggtactc tttaaacaga aaaattacat
     7981 aaaaaaaaga gacggaaata attgatttta gcagaatcaa ttatttctga atcacatggt
     8041 taggacatgt gttcacgctc gtctcaagaa tatgtaagta gctaccaact acttatatta
     8101 aaagttgatc ggataccttt tccgattgcc tttattctac caaaaaaagg cgagcaactc
     8161 aacagaagaa cgtttattta gtgtacttaa attaaatatt cttaaacact gaagagagaa
     8221 cacatactat ggctgagatt aaagctaaac tgtgttctct ttttgtttga gaaaggacgt
     8281 tacaatcgat gttgagcgaa atttattcag ctattcttaa aaacggctta cgtacataca
     8341 aatatcgaaa cagcaccatg aaacctgcag gtcatattga ttccagtagg agtggtgcta
     8401 tctttgcgta ccgtagcaag caattaatga atgttgggcg tggtatggtc attacttcgg
     8461 aagaagctat tttagagaac gaaaagaaac taacgcattg gacacctaat acctatcgct
     8521 ttggtactta tgcggatgat tatcgaacag tggttaaagg tcattctgag aaaaacttaa
     8581 gtcaaatcaa cacatttgta gttgatatcg attcaaaaga gaaccatcaa ggcgaaatta
     8641 ttttagcctg tttagatcaa gtgggctaca tgccaacgct aattttagaa tcagatcatg
     8701 gttatcaagt ttattttgta ctaaagacac caggctatgt cacaaagaaa agcaatttca
     8761 aggtgatcga tgtagcaaaa aaaatttcaa aaacaattcg tctacagttg gctgaaaaat
     8821 tgtccggagt ggatctagga tgtaaccact tcggaattgc tcgattccca caagaaaata
     8881 atattgtttt taaagaaatg aactatcagt attcttttgc tgactggatt caatggtcga
     8941 tgaagcttga atcagatcaa aaaacaaaag aagatcgaga acgaaaacta attgtctttc
     9001 ctgagaaaaa agaaattcgt caagtagatg aaccgtggtt cgatatgtta cttcataaag
     9061 caaacatcgt cggcggagaa ggacgtcttg gtcgaaataa tgtgattttc acgctttctt
     9121 tagcttatta ctcttcaggt tatgcattgg atacttgcga atacaatatg ttcacattca
     9181 acgaacggtt acaggaaccg ctatctgaag cagaattagt aaagattgta cgtagtgctt
     9241 attctggtaa ttatcaagca gcaagcagag aattcattat tgaattgtgc cagcaatggg
     9301 tttcaccaac cttaaaaaat aatgatctgt tcattcaacg acgtggctgg tggaaattta
     9361 aaaagccacg agatcaaaga aaatatagtc ataaaaatga atggaaagaa gatctattgg
     9421 cttatctaag cgaaaaaagt cttgctagtg agccttattt gaacctgtca aaaaaagaat
     9481 tggcttcaca actaacgatg cccaagcgaa cacttgataa gatcttaaat gagttacgag
     9541 aggagaataa agtcttctac aaggtaacac gaggaagaaa tggcggaatg atcattgctt
     9601 cagtcaaaac gttgttcgcg agggttattc aactaagtaa agaaaagaga ctagattatt
     9661 caacaaggat cacagaggta tttggactca acgagagctt agtagaagag acatttagac
     9721 aattatcaac ccccttgaac cctcttaaag aagtgaatct ttttgaagta gatacaggtt
     9781 gaaaaataaa aggtgcaaat tgccttatac aatatatcta tgatacttct gtaggtgttg
     9841 ctccctttgc ctagctacgt gtaggtggta tacttataac tgcgtatgca gtcttatgta
     9901 tcatggagga agttgtatgt cgttaaaaaa ttatgtctat tcacatcctg ttaatgtgtt
     9961 tatcattggt cgtttgggat tatctgtgga agtgttctgt gagctttatg gttttaagca
    10021 ggggactttg tcttcttggg ttaccaggga aaaaacagtt gcttctttgc cgattgagtt
    10081 tcttcatggg ttgtccttag cttctgggga gactatggat caggtatatg attgtttgtg
    10141 tgtgttagag caggagtata ttgagtataa aatagctaac gagttaagaa aaaggaagaa
    10201 gtatatccag tagtagtttt tatttactta aaaaattggt tcattgagca acctatcgct
    10261 gctaaagtag caaaggaaaa cgttaaagga aagaatttag ggaagaaatc gaaatgaaat
    10321 cggacgactg gattgaacac acctggcttc ctctgaaaag aaatagcaaa cgaaagaaat
    10381 tttgggtatt gcaattatgg ccattaggaa aactttgtag ttacggggca cgacttattc
    10441 ttgatttaac cgtttactcg attggagtat ttggaacggc ttattacttg ataaatgatc
    10501 ccaataggat tgcagcatca gacattttta cagtgctaat gacgttgatt tttgtcatgc
    10561 tattgtctat ttttactcaa ttagtcatgc aatttaccag gcaaaaatta acagcaggaa
    10621 aacttttcaa aagcctattc gatttaattg ttgtaaatgc aattctagcg actttaataa
    10681 aacaaattga acaatctgga agaacaacaa aaggagtgaa ggatttttta ttgacgttta
    10741 ttcactttgt aaatggacac atgtatttgt ttgaagtggg tattattctc ttttttgtcg
    10801 ggtatgtatc cacgaaactt attaaacgtt caattgaaaa agaaattgaa attgacctga
    10861 ttccgacact tcttggttat gagtacaatg ttgattttgg aagatatgac gaattgatca
    10921 atacggatat cgttcacacg agtatccatg aatctactgt taagggcatc agatctattt
    10981 taaaaaatgg ccaggaaatg aaagcaatag atcgaagaaa agagatctac aatttttatg
    11041 aagtcgaagc aagcctacga tatggcatcg gaaaattgtg gttagatgga agtaatattc
    11101 gtcaaaacaa accatacatt ttttggaaca gtagtgattt agaacttcca atgaaagata
    11161 aataattatg gagaatcgtt tgaaaatgat tcctctatac aggattgtgc ttatagttgg
    11221 catggagtta aaaaccttaa agaaggagca gttattcaaa gtgaaagaac gtcataatca
    11281 gttactatgt agtaaaacgg gtacgatgaa cattgaatac cgaacagaat atttagaatt
    11341 aacgaatcaa actgattttt tgttgattcg aaagcaacaa gagcaagaaa aaaattaatg
    11401 gctacttata gccaattgat tgatgaatgg gaacaattca aggaatctaa aattccagaa
    11461 cgtctctaaa agcctttatt tgtaaagagc ataaggaaac gtgggaacac tttttaaaaa
    11521 aagtgttcca ataggctgtg cctattacgt ttctcaaaaa taaatgtggg aacaaaatat
    11581 ttaaaaatag gatagtgaaa ggatagtgaa ggatagtaaa aggagggtag taggatagca
    11641 aaaaggatag gctccttttc gctatccttt ttaaattgga ggaattaata tggaagtaag
    11701 aataagaaat gtggatgaga aaatcgtaag agaaattgat cgaagatgtg acgaacggtt
    11761 ctgttgcaaa gttttaaatc tactatcaaa taaggtagaa taatagaaaa agatagcagg
    11821 aggaatgacg atgaatc
//
LOCUS       DADVXE010000080        11782 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.082, whole genome shotgun sequence.
ACCESSION   DADVXE010000080 DADVXE010000000
VERSION     DADVXE010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.082"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            74..1195
                     /locus_tag="KB913_002417"
     CDS             74..1195
                     /locus_tag="KB913_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6820745.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(1277..3049)
                     /locus_tag="KB913_002418"
     CDS             complement(1277..3049)
                     /locus_tag="KB913_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820746.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(3052..4764)
                     /locus_tag="KB913_002419"
     CDS             complement(3052..4764)
                     /locus_tag="KB913_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820747.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            4879..5547
                     /locus_tag="KB913_002420"
     CDS             4879..5547
                     /locus_tag="KB913_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBB6820748.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            complement(5614..6402)
                     /locus_tag="KB913_002421"
     CDS             complement(5614..6402)
                     /locus_tag="KB913_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBB6820749.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6485..7957)
                     /locus_tag="KB913_002422"
     CDS             complement(6485..7957)
                     /locus_tag="KB913_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6820750.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            complement(8087..9280)
                     /locus_tag="KB913_002423"
     CDS             complement(8087..9280)
                     /locus_tag="KB913_002423"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBB6820751.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     regulatory      complement(9278..9357)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            complement(9546..9617)
                     /locus_tag="KB913_002424"
     tRNA            complement(9546..9617)
                     /locus_tag="KB913_002424"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9582..9584),aa:Glu,seq:ttc)
     gene            complement(9629..9702)
                     /locus_tag="KB913_002425"
     tRNA            complement(9629..9702)
                     /locus_tag="KB913_002425"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9666..9668),aa:Ile,seq:gat)
     gene            complement(9715..9785)
                     /locus_tag="KB913_002426"
     tRNA            complement(9715..9785)
                     /locus_tag="KB913_002426"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9751..9753),aa:Gly,seq:tcc)
     gene            complement(9790..9862)
                     /locus_tag="KB913_002427"
     tRNA            complement(9790..9862)
                     /locus_tag="KB913_002427"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9827..9829),aa:Phe,seq:gaa)
     gene            complement(9866..9938)
                     /locus_tag="KB913_002428"
     tRNA            complement(9866..9938)
                     /locus_tag="KB913_002428"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9903..9905),aa:Asp,seq:gtc)
     gene            complement(9957..10030)
                     /locus_tag="KB913_002429"
     tRNA            complement(9957..10030)
                     /locus_tag="KB913_002429"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9994..9996),aa:Met,seq:cat)
     gene            complement(10043..10132)
                     /locus_tag="KB913_002430"
     tRNA            complement(10043..10132)
                     /locus_tag="KB913_002430"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10094..10096),aa:Ser,seq:tga)
     gene            complement(10155..10226)
                     /locus_tag="KB913_002431"
     tRNA            complement(10155..10226)
                     /locus_tag="KB913_002431"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10191..10193),aa:Glu,seq:ttc)
     gene            complement(10248..10335)
                     /locus_tag="KB913_002432"
     tRNA            complement(10248..10335)
                     /locus_tag="KB913_002432"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10299..10301),aa:Ser,seq:gct)
     gene            complement(10360..10433)
                     /locus_tag="KB913_002433"
     tRNA            complement(10360..10433)
                     /locus_tag="KB913_002433"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10397..10399),aa:Ile,seq:gat)
     gene            complement(10447..10517)
                     /locus_tag="KB913_002434"
     tRNA            complement(10447..10517)
                     /locus_tag="KB913_002434"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10483..10485),aa:Gly,seq:tcc)
     gene            complement(10519..10594)
                     /locus_tag="KB913_002435"
     tRNA            complement(10519..10594)
                     /locus_tag="KB913_002435"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10559..10561),aa:Asp,seq:gtc)
     gene            complement(10613..10686)
                     /locus_tag="KB913_002436"
     tRNA            complement(10613..10686)
                     /locus_tag="KB913_002436"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10650..10652),aa:Met,seq:cat)
     gene            complement(10699..10788)
                     /locus_tag="KB913_002437"
     tRNA            complement(10699..10788)
                     /locus_tag="KB913_002437"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10750..10752),aa:Ser,seq:tga)
     gene            complement(10812..10885)
                     /locus_tag="KB913_002438"
     tRNA            complement(10812..10885)
                     /locus_tag="KB913_002438"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10849..10851),aa:Ile,seq:cat)
     gene            complement(10899..10972)
                     /locus_tag="KB913_002439"
     tRNA            complement(10899..10972)
                     /locus_tag="KB913_002439"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10936..10938),aa:Met,seq:cat)
     gene            complement(11000..11072)
                     /locus_tag="KB913_002440"
     tRNA            complement(11000..11072)
                     /locus_tag="KB913_002440"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11037..11039),aa:Ala,seq:tgc)
     gene            complement(11092..11165)
                     /locus_tag="KB913_002441"
     tRNA            complement(11092..11165)
                     /locus_tag="KB913_002441"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11129..11131),aa:Pro,seq:tgg)
     gene            complement(11175..11248)
                     /locus_tag="KB913_002442"
     tRNA            complement(11175..11248)
                     /locus_tag="KB913_002442"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11212..11214),aa:Arg,seq:acg)
     gene            complement(11259..11344)
                     /locus_tag="KB913_002443"
     tRNA            complement(11259..11344)
                     /locus_tag="KB913_002443"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11308..11310),aa:Leu,seq:taa)
     gene            complement(11361..11432)
                     /locus_tag="KB913_002444"
     tRNA            complement(11361..11432)
                     /locus_tag="KB913_002444"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11398..11400),aa:Gly,seq:gcc)
     gene            complement(11444..11516)
                     /locus_tag="KB913_002445"
     tRNA            complement(11444..11516)
                     /locus_tag="KB913_002445"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11481..11483),aa:Thr,seq:tgt)
     gene            complement(11534..11615)
                     /locus_tag="KB913_002446"
     tRNA            complement(11534..11615)
                     /locus_tag="KB913_002446"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11579..11581),aa:Leu,seq:tag)
     gene            complement(11623..11695)
                     /locus_tag="KB913_002447"
     tRNA            complement(11623..11695)
                     /locus_tag="KB913_002447"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11660..11662),aa:Lys,seq:ttt)
     gene            complement(11699..11771)
                     /locus_tag="KB913_002448"
     tRNA            complement(11699..11771)
                     /locus_tag="KB913_002448"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11736..11738),aa:Val,seq:tac)
BASE COUNT         3683 a         2618 c         2089 g         3392 t
ORIGIN      
        1 aaatatataa aaagccttcg ggctttttct tttaacaatt aataggaacg tatattcgaa
       61 aggaatagaa ataatgtggt tagaaaaaat aaatgacaaa aaatttaagt acaccgaacg
      121 ttatacggat cccttaactg aaaaaaagag aaaagtgtcc gttactttat ctagcaattc
      181 acgccaagct tggaatcaag ctaacttact tttgaatgaa aaaatcgcag aaaaaataaa
      241 acgaaatgaa gaattaccac taacttttgg agaattaaaa actaaatggg atgaaaaata
      301 caagccaact gtaaaagaaa gttcctatcg aacaactcag gtttatctat cattaatttc
      361 aaaatatata aaagatgatg tacttgtaaa aaacgttaat agtaatctta tacaagatat
      421 gctagattac tactattttg aaaaaaattt atcatataat tatgtaatac atttaaaaac
      481 ttttacagga atgattttta aattcgccaa ccgtcgatat ggattaaaat ataatcccgt
      541 aaatggggtt tctttagcaa gaaaacctaa gacaaacgaa gaaataaaaa aagaaaaaga
      601 tggttattta tcaaaagaag aagttcaaat gattgctagt aaacaaaaaa gttcacatca
      661 acagtcacgt tattctttaa ttactaaatt tttgttttta actggactac gttatggtga
      721 attgatatct ttgactgaat ctgattatga tggtaataaa attacggttt ctggtactta
      781 tgattacgag ttaaaaatta aaacaacaac taaaaataca ggttcttata gaaccattga
      841 attatcaagt aatgctaaag aaatcataga tcaattaatt gaagaaaaca aattaattaa
      901 gaataataaa gataaataca ttttcatctc taaaaatggt aacccgatat ctattcaagc
      961 atataatcaa tctttaagag cagtatccaa agaattaaac ctagataaaa aagtttcttc
     1021 tcacatgtta aggcattccc acatttctct acttacagaa ttaggaatcc cattaaaagc
     1081 cattatggat cgtgtaggac atgaagattc aaaaacaaca ttaaagattt atactcatac
     1141 aactaaaaat atgcaaaatc aactagtaga aaaactagga aaaatagaaa tttaaattgc
     1201 cccttttctg ccccttataa aaacaaacaa cataaaatat ataaaaagaa ccccgttata
     1261 acgaggttct tttaatttaa ctttcaaata caaattgatt atgataaagt tccgcataaa
     1321 atccattttc tgctaataac tcgtgatgac tgccttcttc aatgacttcc ccatcacgca
     1381 agacaacgat tctatctgca ttcaagattg ttttcagccg gtgagcaatc acaaagctgg
     1441 ttcttccttt gattgcttca tccattgctt tttggatcct tgcttctgtt accgtgtcta
     1501 cattacttgt tgcttcatcc aaaatcaata aagatggatt tgtgatgatc gttcgagcaa
     1561 tactgatcaa ctgcttttga cctgtactga ataagttatt ttcttcggat atctctgtat
     1621 cataaccttt ttctaacgtc atgatgaagt catgaatatt cgcttgtttt gctgcattga
     1681 tgacttcttc atctgaagcg tccggtttgc cgaatgtgat attgtctttg atcgttccgg
     1741 agaacaatac agattcttgc aaaacgattc ctacatgtct acgtaatgca tcaagatcat
     1801 aatctcggat atctattcca tcgatgacta ctgaaccatc attgacatcg taaaaacggt
     1861 ttagcagatt catgatcgtc gttttccccg atcctgttgg accaacaaga gcaaccattt
     1921 ctcctttgtc cacattgatc gagacatctt tcaagactag tttttctgga gaataaccaa
     1981 aatctacgtg ctgcaacgca agaccttttt caacaccatc aaatgcttta cagttttctg
     2041 gtttgacttc atctttttca tcaaatattt cattcaatcg tcttgcccct gtaatcgcta
     2101 attggatcat gctgtatcca gatgaaatct gcatcagtgg ttggtaatat tgttgtgaat
     2161 actggacgaa tgtcacaact aagcctaatg ccaccgaacg ttccaaatca ccatttaatg
     2221 ctaaccagcc gccgaaaaag ataactatcg ctgtattgac cagtgacatt ccttgcatca
     2281 tcggaaatag tagaccagaa taagcttgtc ctttgaaggt tgcttcgcga acactttgat
     2341 tatgctctaa gaatccttca atcgtttctt cttgtaagcc atttgtgatg atgacacgtt
     2401 gtccgctgat tttttcatcc atataaccat ttagtttccc cacttcatct tgctgaagat
     2461 ccacatattt ccgtgctttg cggataatca agacagctat caaaacggct actggagtgg
     2521 aagcaattgt agcccaagct aactctacat tttggcggaa catcatgatc aagatcccga
     2581 caagtaaaac agcattcgtg atgacttgaa gcaaagcttg gttcaaacta ttttgaatat
     2641 tatctaagtc actggtaaaa cgacttaaaa tttcaccgtc ttgatgagaa tcaaagaaac
     2701 ggatcgtcaa tttttccaat ttgttgaata gaccgatacg cattcggttc gttgacttcc
     2761 ctactacttg tgtgaacaaa atactataga taaagttggc tgcactagct agtacataaa
     2821 acagcaagag tttccatatt acagaaacaa atttgctttt atcgtctacg ccttgcatca
     2881 agcctcctac gtaattagct aattcttgaa aagcttcccc gatgtattga ggtgccttta
     2941 cttgtagata ggtagcaatg atcactgtga taaagataaa gaaaaaggag agtttgtacc
     3001 gcttcaaata gtgatagaaa aatttacttg cttttattag atcagtcata cttactcctc
     3061 cgttcctttt tgagtttcaa agatttcctg atagacacgg tttccagcta ccaattcctc
     3121 atgggttcct tcgccgacta atctgccttc atccaatact aagatgcggt ctgctttgac
     3181 aacagaagca attttttgtg cgatgacaat cgtcgttgtt cccttcaaat ctcgatcgag
     3241 tgcttctcgg accagctttt cagagcgagc atccagtgca ctcgtactgt catctaggat
     3301 caagatcttt ggattaccga taacgccacg agtaatggat aaacgttgct tttgaccacc
     3361 agaaaagtta ctgctacgtt cttctattgg tgcttcgtaa cgatcagata acttttcgat
     3421 gaattctttt gcttgagcaa tagaagaagc atgttccatc tctttttctg ttgcattctt
     3481 tttcccttgg cgcaagtttt gagcaatcgt tcctgagaat aaaattgctt tttgcaaaac
     3541 aaaggaaacc gtttgtctta aactcttttc atttacttga cgaagatcta caccacctac
     3601 ttcaactttg ccttctgtcg gatcaaatag acgagggatc aattgtgcta gtgttgactt
     3661 cccggcacca gtcgccccga cgataccaac catttctcca ggtttgatag aaaagctgat
     3721 atctttaagc gtatctgtat cctcaccagg ataacgaaaa gaaacatggt caaaagtgac
     3781 agaacccgtc aactcttgtt ctggaacgtc taaataagta agatctggtt cagcatctaa
     3841 aatttccgca atccgcttca gcgatacggc tgctcttgaa gtcatcatca tcatcattcc
     3901 gccaataatg attgccatca taatctgcat caagtagttc atgaatgaag caattccacc
     3961 aattaacgta ggatcatctt taacaagatc gctcacaaaa aagatcgccc caaccacagc
     4021 caaattggca gccagcatga aggacgggat catcacagaa aataatgtac cgactatgat
     4081 gttgtgtttt gttaagtcct cacttacttt gctgaatgac ttcaattggt tttcttcttg
     4141 tacaaaagat ttcactacac gaatccctag taagttttct tttgcaatgc tattcacacg
     4201 atcaatcagt ttttgaatga tcatgaagtg cttgcccatc cttgtaaatg aaagtgccgt
     4261 aatcagaaat accgtaacga taagcgctac gatgatccac cataattgcg gcatcgtgat
     4321 catagctaaa atgaaggcac caataaataa gaatggaatt cgaaaaagtg attgcaaaga
     4381 aatcatcact aaattttgga tttgcgtgat atcatttgtt agacgaacaa caagatttcc
     4441 agcagagaac tgttcgatat ttccaaatga aaatgtctgg atctttcgaa atgcttcttc
     4501 tcggatatct gcacttacgc cttgagctac ttttgcagag aaaatcgtgt tcgttacacc
     4561 tgcggctaat cctagcaaag ccagactgat caggtaaata ccaattgttt tcatttcatc
     4621 attatcttct gtaataatag cttccaatac ttgctgtagt aacttaggtt gccataatgc
     4681 tgctgcaacc atgactgcta cggacagcaa ggaaataaaa acagctactt tatatttttt
     4741 cgcatgtcgt aagattaatt tcattcgttg attacacccc tttgtttaaa ttgacaggac
     4801 taatttaaca ctgtaaaatt agaccgacta acaatttacc atgtttaaaa agataatgca
     4861 atacacgagg ttgataaaat ggaaataaag ctttctcaag caatcatcat tcaggccgcc
     4921 tttgatatcc tggctgaaac acaagctctt tcgcagcttt ccatgcgaaa catcgcaaac
     4981 agaattcatg ttcaagcacc tgctttatat tggtatttca aaaacaaaca acagctcttg
     5041 caaataatgg ctgaaacaat ggaagaagaa ttagcgcttc cagatccaac tttgccttgg
     5101 aatgaacagt tgctgcagta tatggaaaat tactatgacc tttatacacg tttcccttgt
     5161 ggggcagaat tagaaatcaa tactgtgccc gcttttccga gtcgattaga acatttggag
     5221 caaatgatcc aattacttgt tcgtgaagga ttttcagtca cccaaagtca tcaggccatt
     5281 gcctctctcc acaatttatt gattggacag ttaatggatc agcagcatga acagcagctt
     5341 cgacaaaaaa ttatggacgg aaatgaattt ttgaaagaaa cagttctatt tatgcgtaat
     5401 tatgtagttg aaaatcaatt agagggattt aaagaaagta tgcagtccca tgcagaattg
     5461 aatgaaaaag cactctttct aacgagtgca caaacctata ttgaaggctt atgccaacaa
     5521 aataaaagaa gagaaaacga gcagtaaaaa agctcctata gagatcacta tgtttgtgat
     5581 ctctatagga gctatctttt taagactctt tttttatttt tcttccatta gccacgccaa
     5641 tgcacgttga atccattggt cccagaagat ccagttatga tcgccaggtc cttgttcaaa
     5701 ggtgaccgcc aagccttgtt cctgcatagc agataccatt tcctgatttg cctgataaag
     5761 aaaatcagat tccccacaag ccatataaaa tcttggaact ggttttccgc tttttactag
     5821 ttctttcaat aagtattgcg gatcattttt tgaaccttcg atttgatcca atggtccaaa
     5881 gatcccttcc caaaaagatg ctttacgaac catcaaaaga tcatccattc gatttcctac
     5941 agaaacagcg cctgaaagag agattactgc tgcgaaattt tctgattttg caaggcctag
     6001 ttttaacgcg ccatatccgc ccatcgataa tccagcggca tatgtttttt ctctttttct
     6061 tgttaattgc gggaataatt catgacaaat ctcaggtagc tcttctgcaa tgaatgtcca
     6121 atacttcatg tcataaactg tatctgtgta ccagccaaga tcagtagatg gcatgatgac
     6181 agctaatccg tagtttgcta cataacgttc aatcgacgta cgtctttccc atacactatg
     6241 attgccaccc attccatgaa gtaaatataa aacaggtata tccgttgtct cttgctctga
     6301 actggtgcca atcacctttt ttgttgtttg cggtagtatc acatttagat tgacttccat
     6361 ttctaacaca ttcgaataaa tatttgcttg aataaatgcc atattttcgc cttccttagt
     6421 aagaagttat ttttgaataa ctttaaattt gaatgattcg gctacgtaca tatcttaacc
     6481 gaaactactg ttttatttta ccactttttt catgaacgaa aagcgttaag accaaagcaa
     6541 tgatcacgag taacaagcca actagataaa cggaatgtaa cccatcataa agaatttttc
     6601 ttaatggtaa caaaatatcc gcatcaatat atttagccgt ttgtggattc accagtttat
     6661 tcatgatatc tgcatcattt gttaaatttg ctgctgcaag ttctcgttta gttaccccat
     6721 ttatcaataa accaaaaata gaaaccatga ctgtttgacc aattgttcga actaacgtat
     6781 taaaagaagt tgctacacca agctggtcac gagatacact attttgtgca ctgacagtcg
     6841 aggtagtcat ggtcacacct aagcctatac cgatgaccgt tgatatagca aaaaaccata
     6901 aatagttact tctgaaaggc ataagataca accaagcgcc cccaatagct gcgattagta
     6961 gtccaattct caagacccaa tgagttttca tttgagtcat ccacttgctt gcaaggaaag
     7021 aaccgaccat ccagactagt gataatggtg ctaataccag cccaccaatt gctgcattca
     7081 gccctaatac accttgcatc cacataggga tataaacatc gattcccatc aaaaaaccac
     7141 tagccaatgc tgcagccaag ttgaccacaa caaatagtgg atttttgaat aaatgcatca
     7201 tgatgacagg atctttagct cttttttcgg caaaaacaaa aatacctaac attacgatac
     7261 tacctagcag caaagcagaa acaagcggac tcattccttc gtctcctaat aattggaacc
     7321 ctaacagcaa tgagacaagc atggccatca aactaaaact accaaaaata tccattggtt
     7381 tagactcatg tatgattttt ggttcattta aatatagcca aatcaaaata attaatagaa
     7441 ttccgatcgg cacattgata aaaaagatcc agtgccagct gatcgtttca acgatgaatc
     7501 ctcccgcaag cggtccaaaa acactggcaa tcccccaggc tgaactattc aaacctaaaa
     7561 cttttgctcg cttttcaata gaataaagat cgccgatgat cgtcaaagct actggcatca
     7621 ttgccccagc acccatccct tgaatcgcac gagcagcaat caacccaatc atgctttgag
     7681 ataaaccgca aaataacgaa ccgataataa acaataatgt cccaaaaata aagattggtt
     7741 tccgtcccac tttatccgca agttttccgt aaatcggagt aagcatagcg tttgtcagca
     7801 aataaatcga aaatacccag ttcatgattt ccattccatg taatgaaccg acaatcgttg
     7861 gcatagcggt tgttacgatt gtaccttcaa tagccgtcat gaacgttgca atgaaaatac
     7921 tcactgtgac caaagtaaca tttgtttctt ttttcatctt attcctccct ttcattatga
     7981 caggatctaa aaatagataa ataattacta tctttttcaa gaggttaact gccataaaaa
     8041 aagctggaac aaccaccact tggcgatcgt tccagctgaa tataacttat tttgctaaac
     8101 ttgctttcaa cgcatctact ttgtccgtat gttcccaagg caaatctaca tctgtacgac
     8161 caaaatgacc gtaagcagct gtttgtttgt aaatcggacg acgcaaatca agcatctcga
     8221 tgattcctgc tggccgaaga tcgaagtttt ctctcactgc agcaatcagt tcttcttccg
     8281 gaaccgttcc agtaccgaaa gtattgattg agatcgaaac aggttgagca acaccaatcg
     8341 cataagctag ctgtacttct gctttgcgag caagccctgc tgcaacaatg tttttagcaa
     8401 tataacgtgc agcatagctg gcagaacggt caacttttgt cgcatcttta ccagaaaaag
     8461 caccgccacc atgacgagca taaccgccat acgtatcaac aatgattttt cttcctgtta
     8521 atccggcatc cccttgagga ccaccaatga caaatcggcc agtcggattg atataatatt
     8581 tcgtttgatc atctaataat tcagctggaa taacttcctt cactactttt tcgatgacat
     8641 catgacgaat tgtttcatta tctactgcat catcatgctg tgttgaaata acgattgtat
     8701 ctacgcgttc cggttgtcct tgatcatcat attcaaccgt tacttgagat tttgcatctg
     8761 gacgtaaata cgttaattca tttgatttac gcaaatctgc caagcgtcgt accagacgat
     8821 gactcaaagc gattggtaaa ggcatcaatt ctggtgtttc atctacagca aacccaaaca
     8881 ttaaaccttg gtcaccagca ccaatctcat ctaatacgtc ttttttatct tcatcccgga
     8941 tctcaagtgc ttcatcaact ccttgagcaa tatcaggaga ttgttcatca atcgcaacca
     9001 atacagctgc tgtatctcca tcaaatccga attttgcacg tgtataacca atttctttta
     9061 ttgtttcccg tacgactttt tgaatatcta catatgccgt cgtagatatt tctccaaata
     9121 ctaaaacaag accagttgtt acagacgttt cacacgctac tcgtgctgtt ggatcttgtt
     9181 ttaaaattgc atccaagatt gcatcactga tttggtcagc aattttatct ggatgtcctt
     9241 cagaaacaga ttctgatgta aataagtgtc tttctaccat tataatgatt ccccctagtt
     9301 aaattcggtt acaaggcatc tccgtcctgc ggatcctttc gggaacttgc aacgaaccaa
     9361 gtatagcaga taaaacagtt ttctgctcgt attttttcat ttttttgctt aaaaaatata
     9421 aaaatatttt acattagaac tgtccaaaaa agcttagcac aatcatccat aaagataact
     9481 ctgctaagct ttttaaaatc attctttcag ataaaaagaa aaagatactc aaaaagtatc
     9541 ttccatgacc cgtacgggat tcgaacccgt gttaccgccg tgaaagggcg gtgtcttaac
     9601 cgcttgacca acgggccaat aaaataaatg ggcctaaatg gactcgaacc atcgacctca
     9661 cgcttatcag gcgtgcgctc taaccagctg agctataggc ccataaaaac taaaagcggg
     9721 tgacgagaat cgaactcgcg acaacagctt ggaaggctgt ggttttacca ctaaactaca
     9781 cccgcataat ggcgcgggac agaatcgaac tgccgacaca tggagcttca atccattgct
     9841 ctaccaactg agctaccgag ccaaacggtt ccgacgggaa tcgaacccgc gatctcctgc
     9901 gtgacaggca ggcatgttaa cccctacacc acggaaccaa tgtttttagt ttttaattgc
     9961 gggagcagga tttgaaccta cgaccttcgg gttatgagcc cgacgagcta ccagactgct
    10021 ccatcccgcg ataatatgaa aaaggaggat aagggattcg aacccttgca cggttttacc
    10081 cgcctgacgg ttttcaagac cgttcccttc agccggactt gggtaatcct ccatgtaaaa
    10141 ctatattaaa ttaatgaccc gtacgggatt cgaacccgtg ttaccgccgt gaaagggcgg
    10201 tgtcttaacc gcttgaccaa cgggccaggt aaaacaaaat attgaaacgg agaaggaggg
    10261 atttgaaccc tcgcgccggt ttcccgacct acacccttag caggggcgcc tcttcagcca
    10321 cttgagtact tccccaaaac caataagatt ttgtactaat gggcctaaat ggactcgaac
    10381 catcgacctc acgcttatca ggcgtgcgct ctaaccagct gagctatagg cccataaaaa
    10441 actaaaagcg ggtgacgaga atcgaactcg cgacaacagc ttggaaggct gtggttttac
    10501 cactaaacta cacccgcatg gcggttccga cgggaatcga acccgcgatc tcctgcgtga
    10561 caggcaggca tgttaacccc tacaccacgg aaccagtgtt tttagttttt aattgcggga
    10621 gcaggatttg aacctacgac cttcgggtta tgagcccgac gagctaccag actgctccat
    10681 cccgcgataa tatgaaaaag gaggataagg gattcgaacc cttgcacggt tttacccgcc
    10741 tgacggtttt caagaccgtt cccttcagcc ggacttgggt aatcctccat atgaaactta
    10801 caacgccaca atggaccttg taggactcga acctacgacc ggacggttat gagccgtctg
    10861 ctctaaccaa ctgagctaaa ggtccaggct cttaaaaatc gcggcggagg ggatcgaacc
    10921 cccgacctcc cgggtatgaa ccggacgctc tagccagctg agctacaccg cgaaaaagat
    10981 attcattatt taaatgaaat ggagcctagc gggatcgaac cgctgacctc ctgcgtgcaa
    11041 agcaggcgct ctcccagctg agctaaggcc ccgtgtttaa atttataatt atcgggaaga
    11101 caggattcga acctgcgacc ccttggtccc aaaccaagtg ctctaccaag ctgagctact
    11161 tcccgtttaa ttaacgcgcc caagaggagt cgaaccccta accttttgat ccgtagtcaa
    11221 acactctatc cagttgagct atgggcgcat atttgaaatg ccgaggaccg gaatcgaacc
    11281 ggtacggtga tcactcaccg caggatttta agtcctgtgc gtctgccagt tccgccaccc
    11341 cggcgcgatt gctttggcaa agcggaaaac ggggttcgaa cccgcgaccc ccaccttggc
    11401 aaggtggtgc tctaccactg agctatttcc gcgtgtttaa agatgccggc taaaggactt
    11461 gaaccctcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggcatgt
    11521 aaaacttaaa ttatgcgggt gaagggactt gaacccccac gccgtaaggc gctagatcct
    11581 aaatctagtg cgtctgccaa ttccgccaca cccgcaaaaa tatgagccgt acagggctcg
    11641 aacctgtgac cctctgatta aaagtcagat gctctaccaa ctgagctaac ggctcatatg
    11701 gaggttaacg ggatcgaacc gctgaccctc tgcttgtaag gcagatgctc tcccagctga
    11761 gctaaacctc catggataac tt
//
LOCUS       DADVXE010000081        11251 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.083, whole genome shotgun sequence.
ACCESSION   DADVXE010000081 DADVXE010000000
VERSION     DADVXE010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.083"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(602..967)
                     /locus_tag="KB913_002449"
     CDS             complement(602..967)
                     /locus_tag="KB913_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820752.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1043..1288)
                     /locus_tag="KB913_002450"
     CDS             complement(1043..1288)
                     /locus_tag="KB913_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6820753.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1358..1612)
                     /locus_tag="KB913_002451"
     CDS             complement(1358..1612)
                     /locus_tag="KB913_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820754.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1776..2099)
                     /locus_tag="KB913_002452"
     CDS             complement(1776..2099)
                     /locus_tag="KB913_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820755.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2286..2359
                     /locus_tag="KB913_002453"
     tRNA            2286..2359
                     /locus_tag="KB913_002453"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2320..2322,aa:Ile,seq:cat)
     gene            complement(2744..3241)
                     /locus_tag="KB913_002454"
     CDS             complement(2744..3241)
                     /locus_tag="KB913_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6820756.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3281..4090)
                     /locus_tag="KB913_002455"
     CDS             complement(3281..4090)
                     /locus_tag="KB913_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6820757.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4424..5281
                     /locus_tag="KB913_002456"
     CDS             4424..5281
                     /locus_tag="KB913_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBB6820758.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5274..6176
                     /locus_tag="KB913_002457"
     CDS             5274..6176
                     /locus_tag="KB913_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBB6820759.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6209..6559
                     /locus_tag="KB913_002458"
     CDS             6209..6559
                     /locus_tag="KB913_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6820760.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            6608..7531
                     /locus_tag="KB913_002459"
     CDS             6608..7531
                     /locus_tag="KB913_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6820761.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            7609..8502
                     /locus_tag="KB913_002460"
     CDS             7609..8502
                     /locus_tag="KB913_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6820762.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            8540..9103
                     /gene="amaP"
                     /locus_tag="KB913_002461"
     CDS             8540..9103
                     /gene="amaP"
                     /locus_tag="KB913_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBB6820763.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9117..9305
                     /locus_tag="KB913_002462"
     CDS             9117..9305
                     /locus_tag="KB913_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBB6820764.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9318..10220
                     /locus_tag="KB913_002463"
     CDS             9318..10220
                     /locus_tag="KB913_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6820765.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10252..10494
                     /locus_tag="KB913_002464"
     CDS             10252..10494
                     /locus_tag="KB913_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6820766.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(10750..11121)
                     /locus_tag="KB913_002465"
     CDS             complement(10750..11121)
                     /locus_tag="KB913_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820767.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         3984 a         1925 c         2132 g         3210 t
ORIGIN      
        1 aatagttata agctttttta aagaatattt agaaattatt aattttcgtc tgaaaacaaa
       61 aaaagaaagc gttattattt tagtctattt tcaggggggg aaccttatga taaaaaaact
      121 atttttacta tcaatattaa cgctagcaat ggcaggttgt tctgactctg gcttagcaac
      181 tgaactgatc acaaaatcaa ctgaagccac gacagaggag ttaaaatgtg gaaacgatca
      241 cagtgactac agaggcttaa atcgacgatg catgggaata ttaggcagaa gcaattgtaa
      301 gcatcgatgt agtaatcgaa gaaggtgtag aagaagcaac agaaaaatca aaagaaagat
      361 caaaagaagc aatctgtgct gtgcatcgta tacagacgtc gaagatgcgg tacttttaaa
      421 ccacgtcagg agatgttcat ttatgtctag ggaagttggc gatgaaccaa aactagagta
      481 cgcttttagt tttgcacgtg aggatgaaga taaccctaaa acttacgaca ttttagcttg
      541 atctaagatg gttaaagctt tttaatgaag taagaggaga tagaaggctt ttctagttat
      601 attaggtaag ataaattcct ttttgctcca aatttgctaa acattctgct agataaactt
      661 catcgtgttc cggataaatc ggcacgttgc gctctacagt aggtaaatca aaaaatgctt
      721 cgcatgattt gccacgatac ataggatttt tccactctgg tgctgggctg taaccacgtt
      781 tttccatttc atccatgaca agctgatgat attggaataa tctataagga gaatagtgaa
      841 aaacataatc cacagtagca tgtttctttc cccagccatt tcctcttaat gcacagcatt
      901 cccgatgttg tcctaaaagc tgttgacgag gaagctttga aatcaatttt tcatgccata
      961 atcgcataga aatgtctcct ttatatatag attgttaacc ttagacgtta aatgaaaaaa
     1021 ccagcaccaa ggctggaaaa aatcacttca gtttgcttgc tgtttctgag cgaccaatta
     1081 ggtaatcaac ggaaatatcg taaaagtcag cgatatagat taattcaatg atgcttggaa
     1141 tttcttctcc ttcttcgtac ttacgatatt tgaataaagg aatacttaac gcgctagaaa
     1201 cagctacttg agataaagat cggccagttc ttaagaaatt cagacgacaa cgtaaagtat
     1261 ccagtaaaat agcttcttcg atactcattt aatcaccttt cattatagta gaatagttat
     1321 aatgactata gaaagctaca catgcaatca atagtactca atgtttttta tttaaacgta
     1381 tcaaataaag aatgacgatc aataaagaca aaaccagtcc tgataattct tctataaaaa
     1441 cactatcggg ttcaaagtag ttgtaattaa aaactttcca cataaagtag atagccggaa
     1501 gagtcaaaat agctaaataa aaccgttctt tgttccaatt cataagataa acaatacttg
     1561 cgaccagtgc gaccgcaggc acccaaaaca aaactctcac caacgtaatc atgtaacgga
     1621 ctcctcaacg attcatataa taaaagataa catgttattg catacatcac aaatgaaatg
     1681 ctaggaaaat aaaagaagaa tagatcaatg aaaaatgaaa aagcagaaca gttttctgct
     1741 gataagcagg aactgttccg ctgaatgtgt cttatctatc gagaaaaaat caatggattg
     1801 atatctaagt aattcaatac atataaaaag aggacgatcg cattcactaa aaaggaaaga
     1861 atgatgatcc catagcgaat ggaaacatat ttaacaaata cttttgtttg aatacgggca
     1921 tatctttttc ctttatagct gagcatcatg acaagaagca aaagggtaat cacaccttga
     1981 aaaatcattc caataaacag aattcctgag gtttgataat ttaattggag aaaataagct
     2041 gctgccgcaa ctaaatcgaa taaaatcgca ataaatggca aaataatcac tcctaacatt
     2101 gagaataaat aaaagaataa cattttttct aaaataagca aataaaaatt aaagtaacaa
     2161 aatagttatg acacaagtaa aagaaataag aataacaata ttattttact tatattttga
     2221 aacttgtgag agtttgtcat tcgtgctata gttgaaaagt aacaaaaata aattttattt
     2281 atgatgtacc tttagctcag ttggttagag cagacggctc ataaccgtcc ggtcgtaggt
     2341 tcgagtccta caaggtacat aagaggttgt gaaaaagctg ccctgcatca agtaataaga
     2401 acagccaagt aaaaacagct tcttatgttt ttacttggct gttcttatta ctgcagatgc
     2461 aagcttttga ataccgttta aggaagaggt tgtgaaatca gcgttttgac ctgagtatta
     2521 gcttaacaaa cggaaaaata gttcctcata ttttgccgtt tgttaagcta ataccgaggg
     2581 tcagctgatt gaacaccatt taagaaagag gtcgtgagcc tgccgtttca ctctgtgtca
     2641 taaaaaagcc aatctacttt gatagaaaaa gcacgtagga ctaaaacagt tctgcgtgct
     2701 ttttttattg tgtgttaaat atcgtaaatg aagatagata tttttatgat tcgacgatag
     2761 agacgttgaa atctttcaac agctctaaag cggattctcc gtgttttcta ctggagacta
     2821 acattggatc aacaaaaaag tctgcttcag gaaaagcact ctgcaggcct atcagattag
     2881 agagtacaca caagtttgtt tcaatcccga ctacttcgat ctctttttgt tcttctttgc
     2941 tttcaaataa agtttcctgg atttcagcta aagtttcagg tggaatcgta aagtaatact
     3001 ttttaatcac tcgttcattt tcttgtggag aaagaagagg gatcaattgc aaatcttctc
     3061 gttcttcttc tttgtccttc agttcaactg gtatatcccg tgtgaagaga atatattcat
     3121 tattttggcg tgctttagct aatctttgag caatacgttc tgccaattga tctgactctg
     3181 gaatataaaa ttcgctgttt ggatcaagaa tatgattttg catatcaata ataactaaca
     3241 ttttctttcc tcctacattc atatcgtcat tttattcttt ttaatagaag ttttttaaaa
     3301 tataagcaac accagcttct tcattcgtca gtgttacttg gtttgcaatt tcttttactt
     3361 gtcgctgtgc attccccatc gcaatactca acccgctgta attcaacata gcaatgtcgt
     3421 tttcttgatc gccaaaagcc atgatgtcac tcgattcgat tccaaggtaa tccgccagaa
     3481 aaacaagtga atgagcttta gtgatacctg taggcgtgat ttctaagaaa tgcggatcag
     3541 agaatactga ttggatacca tctgcttgca gatctctttg tagcttctgt agtttttctt
     3601 cactcttatc tgttaatgct aatttaagat agctaagaga aggatcttcc aacatattta
     3661 aaatttgatc aaaagaatgg ttctgtaaat tgaaatgttc ataataaggg tcatctttga
     3721 ctagatttga ttcatcgaat gtcagctgat catcttgggt ttctcggcta gcaatgatgg
     3781 atattttcgc ttcttgagca tagaagaagg cttttctcag tgtatcgcta tctatttttg
     3841 aacgtctgag aactttcgcc atttttccat ccttcatttc agcaatcagt gaaccattgg
     3901 aagaaatcaa atagccaccg attcctaatt cggaaaaaat atctttagca gaaatgctgt
     3961 tccttccggt agcgacggtt acgattccgc cattttcatc aaatttccga agtgcttgga
     4021 tattttcttc tggtatcttt ccatttcgat caagcaaggt accgtctaaa tcaatcgctg
     4081 ctagtttcat tttatcttcc tactttcttt ttacatatct attttcctgt taccttaaga
     4141 ttaaatgaga atttaaaaaa atgaaactaa cttgctttgt cattatgaat tttttcaaaa
     4201 aacattctta agaaaaaggt ggctatatat agtagttttt ggtcaatacc tttgaataaa
     4261 aagccatgaa aaacgaatag ttagcgctta ccgatgcgtt ttgtgataaa aaaattttaa
     4321 aatattcaat gaaaacaaag catatatttt gctttaaaac caaatgagga atattctaga
     4381 tgtagaacag gttagaaaaa gattagaaaa aggagtgatt ttgatggaga agagatacgg
     4441 cgtagttcct gtggtaactg cttcagacga aaattatgct ccttacttga gcgtgatgat
     4501 cgcaactgca ttagaaaatt gcaataaaac aagacgcata aaattttatg tgattgacga
     4561 tggtctatca gaatatagta aagaaggatt ggaagaaacg gtaaataaat attcaagtaa
     4621 tgcaagtatc caattcctga cagtggaaaa agatatctac gaagacttcc tagtcagtga
     4681 ccatatcaca actaccgctt acttaagaat ttctttacca aacttattag ctaaagagga
     4741 ttataagaaa gtcctttact tagattcaga tgtgttagta ctagacgata tcgtaaaact
     4801 atatgatgag ccgttaaatg gaaaaacaat cggcgctatt atcgatccag gccaagtgaa
     4861 agctttggaa agattaggaa tcgattccga tgacttgtac ttcaattcag gagtgatggt
     4921 gattgacatt gatcaatgga ataaaaaaga aattacagaa aaaactatcc attacctcag
     4981 tgaaaatggc gatcgaatca tctatcacga ccaagatgct ttgaatgctg tactttatga
     5041 agattgggaa caacttcatc caaaatggaa catgcagact tcgctgattt ttgaacgtca
     5101 tccagcacca aatgaaaaat atgaacgtca gtataaagaa ggaaatgaaa aaccttcgat
     5161 cgttcacttt acaggacatg ataaaccttg gaatacgttg aaagatcatc cgtataccaa
     5221 tttatactta aaaaaattag cacacagtac tctaacgaaa gtaggcgaga tcaatgaata
     5281 aaaaagaaat agcagtagtc gcaagttgta acacaaaatt cgtaccacat ttagctgcat
     5341 tatttgtctc agtattagat aattgcaacc cgtctaaatt tgttcggttc tatgtgattg
     5401 acgatgatat cgattttgaa agtaaacagc ttttacgctt ctcagtgaaa aacgcacgaa
     5461 tgaactcaga tgtggaattc ttgaaaatca ataaagaatt ctttacaaat gtggtaatca
     5521 gcgatcgtat tccagaaaca gcttattatc gtattgcgat tccggaattg ttccgcggca
     5581 cagaagttga acgtatctta tatatggatt gcgacatgat cgctttacaa gatatctcta
     5641 aattatggcg tcttgacttc ggtgattcaa tcgtagcagc tgttgaagac gctgggttcc
     5701 atcaacgact ggaaaaaatg aaaatttcag ctaaatcaat gcgttatttc aactcaggtt
     5761 tgatgctgat caatgtgaaa aaatggttag atgaaaatat tacgcaaaaa gtattagatt
     5821 tcatcgaaca taatccagaa aaattacgat tccatgacca agatgcatta aatgctatct
     5881 tacatgaccg ttggttacca cttcatccgc gttggaatgc acaaggctat atcatggcaa
     5941 aagcaaaaaa acatccaaca gcagcaggtg aacgtgaata cgaagaaact cgcaacaatc
     6001 cttacattat ccatttttca ggacatgtga aaccgtggag caaggatttt gaagggccaa
     6061 cgaagaaata ttacgaaaaa tatgcaggga tgacggcttt ccgttgtgta gctaaattcc
     6121 ctaaatatcc aaaatatgca aaagttcaac caaaaacaga tgtagttgtt aaataataga
     6181 agaccacaac tgaagagggg gagtaggaat ggaaattaca atgtctaaaa atgcagtaga
     6241 gacgttaatt gaaaaggttg gggaaaatac aaaaatcgca ctcgcgctta tcaatgattc
     6301 cgatccattt ctaagggaca aaggtgcttt tgcaaaaggc agcttttttc aaatcattcc
     6361 ttttgtttcg gaatttggag aatatgcgac taaaatcgag catccattat tggacatcta
     6421 tacatctaaa ttagagcaaa attatttcgg taaacgattg aacatggact tcaacaaaca
     6481 gcttgacagc ttttcattag aaaatgaaat cgcagtactc gattataata tcaaattaaa
     6541 gaactgcttc ttcagctaat agtttcgaga aagtccaaaa aggaggtata cattgagata
     6601 ctactttgtg gatgaagaaa agaatgtaat agaaacagat gaaaaaaaat ataattggct
     6661 cgtacttgat agtgcaaagc ccgaagagat tgagcaagca atcgaagaat tcgagcttcc
     6721 tgatgatatt ttcgtaggaa ccgaatatcc ggaagaagtt tctcggatgg agcgccttta
     6781 tgagacgaaa ctagagcatc cattttcttt ggtagtgatt aatctagatc agtcagataa
     6841 tcgtatcgaa aaaaaattaa cgccaatatc ttttgtactt tccgataatc tcttgattac
     6901 ttgtatcgat agaaaaaccg aatttgtgga tcggctgctg acaaagcatg gaaatcattt
     6961 aaactcgttt gaaaagatca tcacgtatac attattagat atttacaccc attacgtgaa
     7021 agaactaaga gagatgaaaa agcgaattga cgctttggat aaagcagctc gtaaaacaac
     7081 ggaaaatgaa gaactgtata aacaggcaga tcttgaaaga gacatcgtat atatcgatca
     7141 taccttaaga gatcaacggg aaacaatgga tcaattatgg aattctgaaa ctttcatcaa
     7201 acgtttagac gatgaacagc tactctatga tgtccatttg agacagcgac aaacagaaaa
     7261 aatgatcgag atctatcgag atttattaga gagtattggt gatctattca acgggatgat
     7321 ggacaataat ctaaatcata tcatgaaata tctagattca gctgcattaa tcatttccgt
     7381 tccggcgttg ttcgcaggga tttggggaat gaatacagga ggattaccgg gtaaaagttc
     7441 tgctctaggc tttatactcg tagtctttgg ctctttgata gcagcagtag ttttaggtta
     7501 ccatttatac cggaaagatt atacaaatta aagaatctat ttaaaacagg tatcaaacaa
     7561 agaaatttgt tttggcaata caatttaaaa actaggagga atacagcaat gacagaacca
     7621 aaattaatcg acccgcgaaa cttgtaccat acggagaaat ttcctaaaca agatcaggat
     7681 acaccagctt tacagcagaa tatgattcct gttcctgatt gtggagaaga atcctatgaa
     7741 ggcaataatc aactagaaaa ccgccgtgta ctaatcactg gtggagattc agggatcggt
     7801 cgtgcagcag cgattgcatt tgctagagaa ggggcagata tcgctcttca attcttccca
     7861 ggagaagaaa aagatgcaga ggaagtagca aaatacgtga aagatgcagg acgtaagatt
     7921 gtcttactac cttttgatct tcgtgacgaa caagcaccta aagaaatcat agataaagcc
     7981 gtgagtgaac ttggcgggct agatacgatg gtactaaacg caggacagca aatttcttgt
     8041 cagtctattg ctgagttacc acttgagcaa gtcaaagaca catttatgat aaacatcatc
     8101 gctatgtttg ctttagtgaa agaagctgtt ccgcatatcc cagcaggagg agcaatcgta
     8161 acaacaactt ctgttcaagc attcaatcca agcgaacatt tattagatta cgcagcaaca
     8221 aaagcttcaa tcgctaactt tacgatcggt ttagcaaaac agcttgcacc taaaggaatc
     8281 cgtgtaaatg gtgtagcacc tggtccaatt tggacaccat tacaactaga cgaaggacaa
     8341 ccttctgatt cgatccctga atttggtcag caaagtttac tagaacgtgc aggtcagcca
     8401 ggagaattag caccagttta tgttttctta gcatcgaata aagcaagtta tgttacagcc
     8461 caaatttacg gagtaactgg tggagaagcg atcaacttat aagaagttga tcgtttcacc
     8521 cctatgagga ggtgcgaaaa tgaataaagg tgtaaaaacg atcggagtga tcggaacatt
     8581 acttttgcta tctgtgcttt tgtttgcgat actattaagt gcaacctatc cattgccttt
     8641 tcagctagag aagtttcgat tcttttccat cactaattca tacgtgcaac aatatgtatt
     8701 ttggcttgcc gttgcatttg ctattttgac aattatcacg ttacttgttt tcctgtttta
     8761 tccaaaaaca atcggaaact ttctactgaa acatggtgat ggggagttga cgttggataa
     8821 aaaagcaatt gaaggaatgg ttcgttctca cttgcatgaa gatgaattca tccattcacc
     8881 aaaagtaaat gtcaaagcaa cgaaaaacaa gatcgccgtc aatgtaaaag gggagttgaa
     8941 acgaacttca gcactcattg gtaaaacagg aacattgatg aaagaaatcg aaaatgaagt
     9001 acaacacata ttgggaacaa aagagccagt gaaagtatcg gtgaaataca caggctttga
     9061 agaaccagct aaacgaagca atgaccgcaa acgagtagaa taggggggga ccaaaaatga
     9121 aagaactatt ttcgacatac aagctcccta tcatctttgg ggtacttgga ttgatattag
     9181 ccgttttatg gatcaccgtg ggctttttca agaccttatt gatcttgatc atggcagcga
     9241 tcggcgtcgc tatcggtttt tatctgaaac aaacgaaaat cttagatcac tattttaaat
     9301 cttaggagga aacatccatg aataacaata acaaaaataa taacaataaa atgaacaacc
     9361 aaaaaccagt gtctgcacat ccagacccaa cgacaccaaa ccaatcaaat ggtgtgaacg
     9421 atgaaaagaa caaaacagca ccagtatctg cacatccaga tccagtagtc cctaacgttc
     9481 aacaaggagt agaagagaag aaacatgatg cagaaaagca tgcacctcat catccaggaa
     9541 ctccagaatc taaagttcca gaacaacatg atgcaatcga tccttctaaa cctgtggaag
     9601 agcaaaaaca tccttctgac catgcgaaag cacaagaaaa acttagttct gaccacacaa
     9661 acggacaagg aaaacttggt tctgatcata caaataacca aggaaagcat gattctgaac
     9721 aggaagattc aatgcgcggt gagctgaatt atgaagataa agttgtgcaa aaaatcatcg
     9781 gaatcgcaat tgaacaagta gacggtttat tatctgcaaa cggtggtttc ttctctaatg
     9841 tggcaggaaa acttgtgaat acagataatg taacggctgg gatcgaaaca gaagtcggta
     9901 aaaaacaagt agcagttgat atggatgtca ttgtggaata tggcaaagat atcgaaaaaa
     9961 tctttgaaga aatgcaagaa gtaatcggca aagaagtaaa aaatatgaca catttagaag
    10021 tgatcgaagt caacgctaac gtagtggaca tcaaaacaaa agaagaattt gaaaaagatc
    10081 aagaaacggt gcaagacaaa gtaactgacg cagcgaaaaa aaccggtgaa tttgcttcga
    10141 atcaaacaga taaagtaaaa tcagcagctg gaagcggcgc acaaaaagta aaagaaaata
    10201 cagaaccacg ggttcagtaa taaggaagta aaacattagg aggaacgaaa catgggattt
    10261 atttggtcac ttatcgtcgg aggaattatc ggagcaattg caggagcaat cacgaataaa
    10321 ggttcttcga tggggattat tgcaaatgtc gtagcaggtt tagttggatc agcacttggt
    10381 caagcattat taggttcttg gggaccaagt attgcaggaa tggcaatcgt gccatcattg
    10441 attggtgcca tcattttagt actaatcgta tcattctttg ctcgaaaact gtaaaaagac
    10501 ttttaaaaag aggtcgtgaa aaagctgttc ttcatcaagt aataagaaca gccaaacaaa
    10561 aatagcttct catatttttc atttggttgg gcatattatc gaagatgcaa gcttttgaac
    10621 actgtttata cggaataaga ggctgtgaca agacttttgt cacagcctct tatttatgcg
    10681 ggcaaattcc caattagatt tttaaaagtt tttccttaaa tgtgtcttta ttgatacaga
    10741 gaagcttctt taataaaaca atgcctccct aaattttctt gagataggaa aggtgaacat
    10801 acaaaataat acgaccactt tgaaaaccca gatgatccac aaatggatcg tatgatactg
    10861 atgaagtaaa aagcaatgga tcagaaactc aaagagattg aaaaagacaa ggaagaaata
    10921 atatctcttt tttactcttg tctgttttag ccaataatag ctcgtaaagt aatctagaca
    10981 aacaaataga agtaaacaaa gtttcgtaag agcagcaatc gtatcatgtt gctctgctag
    11041 acgattgacg agcaggaaaa atgttggtaa tggaatatag atcacgagta atgaaagaaa
    11101 aaagtaaaca ataaatggca tactattcct cctaattgtg tgagttcgcc ctcattttaa
    11161 aataacgata tttgtttgtg aagctttttc gtgtcgtaac aaatgttatc taatgtattt
    11221 ttaaataaat aatcattatt atcaaaataa t
//
LOCUS       DADVXE010000082        10688 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.084, whole genome shotgun sequence.
ACCESSION   DADVXE010000082 DADVXE010000000
VERSION     DADVXE010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.084"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..450)
                     /locus_tag="KB913_002466"
     CDS             complement(<1..450)
                     /locus_tag="KB913_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6820768.1"
                     /translation="MKYKEMFVPSLIQLAVEVKNKEEAFLIAAQQLEKMGYVNENYLN
                     GLIAREREFPTGLITKYLNIALPHSECEYVEKPFVFVMQLKNPIYFYQMGDNQEMTVE
                     NLFFLGIKEPKEQVGLLQAFMNLFMDETFVENYKKQETPQNIYELITN"
     gene            674..1465
                     /locus_tag="KB913_002467"
     CDS             674..1465
                     /locus_tag="KB913_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6820769.1"
                     /translation="MLKKERQEQIITLLEKDFYLTNSEIANKLGVSEMTIRRDVTELA
                     KKNKVKKLYGGVERKEPYNRELSTQEKIDTNVAEKKYIGQVMNSMIPDNSTIYVGAGT
                     TILYALPFIQKKNLFVITNSLIAFNYLKNHTSYRILLTGGEFSPITEEFIGEVAERSF
                     ESLNVDISFAATNGIFDNNVTTAQFIEGNIQNAALNAAKIKCIVADYSKLNKSDVYTF
                     RKLTDFDYLITDNHLSEQDFNHYSKYLTILKEPKNDTDNHDEPIH"
     gene            1431..2384
                     /locus_tag="KB913_002468"
     CDS             1431..2384
                     /locus_tag="KB913_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBB6820770.1"
                     /translation="MILTITMNPSIDSIYFTKHFELGTMTRFDSPVRYVGGKGINCGR
                     ASALLGSSVILTGFLGGYFGSMIQDMLKNENLFDLHFLPIAEESRGAVTIMHDDETQT
                     ELVEAGPEIADTTIKKLMNDIKLISKNNYLSVITINGSVNNPDPFLYAKLLQYIKEQI
                     DPSTYILMDISGQHLREVLASKYKPMFIKPNIHEFSDIIHQKITQKSDIKHHLKTNPL
                     FKDIDVIMISCGSYGAVVKVKEEFWNVEIPKIPIINTTGSGDATVGGFAHSLEQNYPL
                     KECVRYAMACGMSNAQQSEVGKVIPADVKNLAKSIKITEMK"
     gene            complement(2782..3756)
                     /locus_tag="KB913_002469"
     CDS             complement(2782..3756)
                     /locus_tag="KB913_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6820771.1"
                     /translation="MNKELNITQEWDKVFPKSNQVNHRKVSFPNRFGITLVADLYEPK
                     EVSEKKLPAIAVSGPFGAVKEQSSGLYAQTMAERGFLTIAFDPSFTGESGGVPRYVAS
                     PDINTEDFQAAVDFLSVQKNVNPERIGIIGICGWGGMALNAAAIDTRVKATVVSTMYD
                     MTRVTANGYFDVMDENARYEMREELNAQRIIDFKQGDYARAGGVVDPLPEDAPQFVKD
                     YHAYYKTDRGYHVRSLNSNDGWNRTSGLSLMNAKLLHYIPEIRHAVLVIHGEKAHSRY
                     FGEDAFKELKGDNKELMIIPGASHTDLYDQTDIIPFEKMATFFEENLV"
     gene            3871..4305
                     /locus_tag="KB913_002470"
     CDS             3871..4305
                     /locus_tag="KB913_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6820772.1"
                     /translation="MYSIGQVSEMFGLPVSTLRYYDKEGLFPDIQRVSGIRKFSENEL
                     EALRVIDCLKKSGLEIKDIKQFMEWSKEGSKTFEVRKELFEKQKEVVEKEIAKLERVL
                     AMLNYKSWYYEEAIKAGNEEAVLTMIPDDLPQHVKEAYVHSH"
     gene            complement(4430..5452)
                     /locus_tag="KB913_002471"
     CDS             complement(4430..5452)
                     /locus_tag="KB913_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HBB6820773.1"
                     /translation="MKKIGFLSFGHWMEQGSLVKSAQDAYLQSIDLAVEAEKIGVDGA
                     FFRVHHFAPQIGSPFPLLAAIGAKTSKIEIGTGLIDMRYENPYYMAENAGLTDIITQG
                     RVQLGVGRGSPEQVLDGWKYFGYDYSEEEIKEVTRERTLEFLELLEGKPFEEPNPQPM
                     FPQGSGKLRIEPYSEGLRQRIWWGAGSQQTAIWAAQHGMNLQSSTLVNYESHEPFHIQ
                     QANQLRAYKEAWKQAGHDFEPRTLVTRSIQPITTDLDRRLFGQDGSPQQDAVGYLAYH
                     RNPTIFGKTFAGEPDQLIKELAEDEAIKEADTVLVTIPNTLGVEYNMHLLETIVKDIA
                     PELGWR"
     gene            5844..6266
                     /gene="arsC"
                     /locus_tag="KB913_002472"
     CDS             5844..6266
                     /gene="arsC"
                     /locus_tag="KB913_002472"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HBB6820774.1"
                     /translation="MKKIYFLCTGNSCRSQIAEGYARKYLSPSMFEIRSAGIETHGLN
                     PRAIKIMAEDGIDISKQTSDLIDRDYFTQADLIITLCGDAKDKCPAVPNNHEHLHWDL
                     KDPAQAVGSEEEILTEFRKVREGIKRKVLDLNQRTSIV"
     gene            complement(6546..8468)
                     /locus_tag="KB913_002473"
     CDS             complement(6546..8468)
                     /locus_tag="KB913_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBB6820775.1"
                     /translation="MNQRQQSLIYQLSENNNYITTKKLAEHFHVSERTIHSDLNTIET
                     WLRDKHLPLMFERKKGTGILLNGLPHEREQLKRALNEETQTEMDKKQLRQLLIFHLLV
                     AKDGFSLEELSEKLYVGKRTIRKELTELQSFFEYHHLQLVSKTKLGTFLKGDEQEKRQ
                     LLVKTLRNMQKEDPQSPSLKEFFAKDTLKVIQHTLQDVFYENHLEQPNGLASVEIHIY
                     FMLERMKQYQKVKLSKDENEVVEHTQAQKLSSQILAKLATIYPIEFSPDEINYLALRI
                     ANLFTNSQAATRFQKESSALADHLIEQVEQFLGYSLKEDQLLKQNLRSHLSSTYFRLH
                     YGLQISNPLTKNVFSTYTQLFLVLQLILEDYFEKENFYVPQEETAYLTIHFQAAIERH
                     KHQKSRRYQTVLVSEYSKAMATFLEARLNRELPELTIMDLVEYKPELKRQDFPSVDFI
                     LATLPFKHISIPVIEISPMITETDLAYLTKYMLEHVPIKKKKTFDLASFTHPFLIFPQ
                     LERTDPADILNFMGNVLVEHHYVEPEFIDSVLERDSHSSTRVAPFVTIPHGNPLYVKH
                     SMISIATMKEPVLWHGEQIRIVLLLAIKKNDLKHAEFKKIFSVIHYLEKQPEQMAQLM
                     QSNHPLEILTLLSSYE"
     gene            complement(8555..10495)
                     /locus_tag="KB913_002474"
     CDS             complement(8555..10495)
                     /locus_tag="KB913_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBB6820776.1"
                     /translation="MKKIIAITSCPVGIAHTYMAAENLEKAGKAVGAEVKVETHGSIG
                     IENELTARDIEEAAGVIIAADTKIDKSRFGGKPLITVGVQEGIHHADELVRDILAGKA
                     PVYKSTEAIISSENKSESENLGKKIYKSLMNGVSYMVPFVVTGGLLIAISLTLGGTAT
                     PEGIKIPEGTIWATMNSIGSIAMGLMVPILSAFIAQSIADRPGLVPGFVGGMLAANGA
                     LYGSDANAGFLGGIITGFLAGFIALGIKKVRVPKALQSIMPIIVIPILGSLAVGFVFI
                     YVIGEPVALLFSSLTHFLAGMQGGSEIVLAMILGAMIAFDMGGPFNKVAFLFGSGLIA
                     EGNYSIMGPIAVAICIPPLALGLASLILKTKFTKTEREAGKASLAMGLFGITEGAIPF
                     ASTDPLRVIPSIVIGAMTGSVIAMLSGVTDHVAHGGPIVAVLGAVDHVAMFFVAVIAG
                     IAVTVLMLRILKPTLQQTAVAAANGVTVADLSETETSDVYTKTETFDSITDIMSDEAI
                     VLGETATTKDGVIEDLVQRLEKTAAITDKTRFKEVIYDREHESTTGIGMGIAIPHGKS
                     AYVLKPTVAFARSQSGVDWHSLDGKPAHMIFMIAVPENSQGDMHLKILQRLSRKLMDD
                     DFRQALMEAPDKTTVHQLLSEM"
BASE COUNT         3273 a         2088 c         1826 g         3501 t
ORIGIN      
        1 atttgtaata agttcgtata tgttttgcgg tgtttcttgt ttcttgtaat tttccacgaa
       61 tgtttcatcc atgaataaat tcataaacgc ttgaagtaat cctacttgtt cttttggttc
      121 tttgattcct aaaaaaaata gattttctac agtcatttcc tgattatccc ccatttgata
      181 aaaataaatt gggttcttca gctgcataac aaaaacaaat ggcttttcga catattcaca
      241 ttccgaatgt ggcagcgcga tatttaaata cttagtaatc aatccagtag gaaattctct
      301 ttctcttgca atcagtccat tcaaataatt ctcattgacg taccccattt tttctaattg
      361 ttgtgcagcg attaaaaaag cttcttcttt attttttact tctaccgcta attgaatcaa
      421 actaggaacg aacatctctt tatatttcat tccaacctcc tcctttttga ttaagtttgt
      481 taatttattg ttctactaaa ttcatctttg ttttacaaga acattatatt tctgttagtt
      541 tgttttgtca acgctttcaa aagaaattta ttttgttaaa tttgatctac ttgaaaataa
      601 aatcgtttat ctatataatt aagaagaaca aagtcgaaca aaaattgact tttatgttaa
      661 aggagtaatt catatgctga aaaaagaaag acaagaacaa atcattacat tattagagaa
      721 agatttttat ttaactaatt cagaaatcgc taacaaatta ggcgtatcag aaatgaccat
      781 acgccgagat gtcactgaat tagcaaaaaa aaataaagta aaaaagctat atggtggcgt
      841 tgaacgaaag gaaccttata atcgagaact atcgactcaa gaaaagattg atacgaatgt
      901 agccgaaaaa aaatatattg gtcaagtcat gaacagtatg attcccgata attctactat
      961 ttatgtcggt gctggaacaa cgatcctata tgcacttcct ttcattcaaa agaaaaatct
     1021 atttgtaatt acaaacagtt tgattgcttt caactattta aagaatcata caagttatcg
     1081 gattttactt actggtggcg aattttctcc tattacagaa gagttcattg gggaagttgc
     1141 agaaagatct tttgaaagtt tgaatgtcga tatctctttc gctgcaacaa acggcatatt
     1201 tgataacaat gtgacaaccg ctcaatttat tgagggaaat attcagaacg cagcgctcaa
     1261 tgcagcaaaa atcaaatgca ttgttgcaga ttattcaaaa ttaaataaat cagacgtcta
     1321 tacttttaga aaattaaccg attttgatta tctaataacc gataatcatt tatcagaaca
     1381 ggatttcaat cattattcaa aatacttaac aatattaaag gagcccaaaa atgatactga
     1441 caatcacgat gaacccatcc attgattcca tttattttac aaaacacttt gaattaggta
     1501 cgatgacacg ctttgattct ccggtacgct atgtaggcgg caagggaatc aattgcggac
     1561 gagcttctgc tctactaggt tcatcagtta ttttaacagg gtttttgggc ggttattttg
     1621 gcagtatgat tcaagatatg ctgaaaaatg aaaatttgtt tgatttgcat tttttaccta
     1681 ttgcagaaga atcaagaggt gccgtcacga tcatgcatga tgatgaaacg cagacagagc
     1741 tagtggaagc tggtcctgaa atagcagata ctactatcaa aaaattaatg aatgatatca
     1801 aactaatcag taaaaataat tacctttcag tcattacaat aaatggttct gttaacaatc
     1861 cagatccctt tttgtatgct aaattattac aatatatcaa agaacaaata gatccttcca
     1921 cctatatatt aatggatata tctggacaac atctccgtga agtcttagca agtaagtata
     1981 aaccgatgtt catcaaacct aatatccatg agttttcaga tatcatccat caaaaaatta
     2041 ctcaaaaaag cgacataaaa caccatctaa aaacaaatcc actatttaaa gatatcgatg
     2101 ttatcatgat ttcttgcggc tcgtatggtg cagtagtcaa agtaaaagaa gaattttgga
     2161 atgttgagat ccctaagatt cctatcatta atacaacagg ctctggggat gccactgttg
     2221 gaggttttgc tcattcatta gaacagaatt atcctttaaa agaatgtgta aggtacgcaa
     2281 tggcttgcgg catgtcgaat gcacagcaat cagaagtcgg gaaagttatt ccagctgatg
     2341 taaaaaattt agcaaaaagc attaaaatca cagaaatgaa ataaatagta caaagtaaat
     2401 aattgtttat atgaaatgag acacaaagag actgtgacaa aaaacgtgtg taccgacccc
     2461 caaaagttag attttttggt ctaacttttg ggagtcgata cattgtcaca gtcctttttt
     2521 cgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
     2581 gagaagctat tttttgaaat tgctccttgt gactcagagt taaacggcag gctcacgacc
     2641 tcttggtata aacggtgttc aaaagcttgc atctacgcta atgagtccaa ccaagtcaaa
     2701 aatgaggagc ttttttggct gtccttatta cttgatgcag ggcagttttt tcataatctc
     2761 ttttagatta aatccttttg gttacacaag gttctcttca aagaatgttg ccattttttc
     2821 aaatggaatg atgtctgtct ggtcgtatag atctgtatgg gatgctcctg gaatgatcat
     2881 gagttccttg ttgtcacctt ttagttcttt gaaagcgtcc tccccaaagt aacgtgaatg
     2941 agctttttcc ccgtgaatga ctaagactgc atgacggatt tctggaatat aatgcaatag
     3001 ttttgcattc ataagtgaca accctgatgt cctattccaa ccatcattgg agtttaaaga
     3061 acggacatga tatccgcggt ctgttttata atacgcatga tagtctttga caaattgagg
     3121 agcatcttca ggcaacggat caaccacacc tccagcacgt gcgtagtccc cttgtttgaa
     3181 atcaatgatg cgttgtgcat ttaattcttc acgcatttca tatcgggcat tttcatccat
     3241 aacatcgaag tagccatttg ctgttactcg agtcatgtca tacattgtgg aaacaactgt
     3301 tgctttgacc cgcgtatcga tagctgctgc attcaatgcc atacctcccc atccacaaat
     3361 accaatgatt ccgattctct cagggtttac atttttttgt acagataaaa agtctactgc
     3421 cgcttggaaa tcttccgtat tgatatcagg cgaagcaaca tatcgaggta ctcctccgct
     3481 ttctcctgta aacgatggat caaacgcaat cgttaaaaag cctctttcag ccatcgtctg
     3541 cgcatataga ccagacgatt gttccttcac tgcaccaaat ggcccgctca cagcgattgc
     3601 cggcaatttc ttttcactta cttcttttgg ttcatataaa tcagcgacta atgtgatacc
     3661 aaaacgattc gggaagctca cctttcgatg attgacttga ttgctttttg gaaatacttt
     3721 gtcccattct tgtgtgatgt ttaattcttt attcatattc tagactctcc tttgatcaaa
     3781 attgacattt gtttttgaat gtattattat gataaaactt aaacttgact ttaggtcaag
     3841 gtaaaaattt tattttagga ggattttttt atgtattcca ttggacaagt gtctgaaatg
     3901 tttggattgc ctgtttctac tttacgttat tacgacaaag agggattatt tcctgatatc
     3961 cagcgtgttt ctggtattag aaaattttca gagaatgagt tagaggcttt aagagtcatt
     4021 gactgtttga aaaaatctgg tttagaaata aaagacatta agcaattcat ggaatggagc
     4081 aaagaaggca gtaagacatt tgaggttcgt aaagaactat ttgaaaaaca aaaagaagta
     4141 gtagaaaaag aaatagcaaa attagaaaga gtactcgcta tgctaaacta caaaagctgg
     4201 tactatgaag aagcaataaa agccggcaat gaagaagccg tattgacaat gattcctgat
     4261 gatttacccc aacatgtaaa agaagcttat gtacattctc attgaacaaa cggataactc
     4321 actctccttc tctatgaact tcatgaaaac atgaataaac acctctaact gattgttaga
     4381 agtgtttatt ttttcactca agtatcctgc acttacaaaa atatcctttt taccgccatc
     4441 ctaattctgg agcgatatct tttacgattg tttcaagcaa gtgcatgtta tattctaccc
     4501 ccaaagtatt aggaatcgtg acaagtactg tgtctgcttc tttgattgct tcatcttcag
     4561 ctagctcctt gattaattga tcaggttcac cagcaaaagt ttttccaaaa atcgttgggt
     4621 ttcggtgata agcaagatag ccgacagcat cttgttgcgg actaccgtct tgtccaaata
     4681 agcgtcgatc caaatcagtg gtgattggct gaatcgagcg agtaactaat gttcttggtt
     4741 caaaatcatg acctgcttgc ttccacgctt ctttatacgc acgtaattgg tttgcttgtt
     4801 ggatatggaa tggctcgtgg gattcgtaat tgactaatgt agatgattgc agattcattc
     4861 catgttgtgc tgcccagatt gccgtttgct gcgaaccagc tccccaccag attctttgtc
     4921 gtaatccttc tgaataaggt tctatccgta attttcctga tccttgtggg aacattggtt
     4981 gaggatttgg ttcttcaaat ggttttcctt caagtaattc caagaattca agggtgcgtt
     5041 cccgtgttac ctctttgatt tcttcttcac tgtaatcata accaaagtat ttccagccat
     5101 ctagaacttg ttcaggtgaa ccacgcccca ctcctagttg cactcttcct tgcgtgatga
     5161 tatctgtcaa tccggcattt tctgccatat aataagggtt ttcatatcgc atatcaataa
     5221 gtcctgtacc gatttcaatc ttacttgtct ttgcgccgat tgccgctagc aaaggaaacg
     5281 gcgacccaat ctgaggggca aaatgatgta cgcggaaaaa cgctccgtcc actccgattt
     5341 tttctgcttc caccgctaaa tcaatcgatt gcaaataagc atcttgagct gatttcacaa
     5401 gcgatccttg ctccatccaa tgtccaaagc ttaaaaagcc gatttttttc aaggtaatga
     5461 cctcctttaa acctacaaaa atggaaggtt ttttattttt aatatgaact gattctacta
     5521 ctttttttct taaaagacga ataattgttc tcgcctcaca atcaagaaat gtatcggctt
     5581 actacacccc tactttcttc atcatctgcc gtgtcttaat ctcttttaac agtctgttac
     5641 atcgttgatt tttgactcaa aatgattgtt tctaacatgt atttatggta aaaaagacaa
     5701 gattagttct ttgtacacat cgatttatac gctgaacaaa aagaaatata taaactaaga
     5761 aacccattgt tttttcgctc catcacatag agtttacttt agataaacag tgacatttac
     5821 taatccataa cggaggaaat caaatgaaaa aaatctattt cttatgtacg ggcaattcat
     5881 gccgcagtca aatagcagaa ggctacgcgc gtaaatactt gtctccttca atgtttgaga
     5941 taagaagtgc ggggatcgag acacatggct tgaatccaag agctataaaa atcatggcag
     6001 aagacggcat cgatatttcc aaacagacgt ctgatttgat tgatagagat tactttactc
     6061 aggcagactt gatcattaca ctttgtggtg atgccaaaga caagtgccct gccgttccaa
     6121 acaatcacga acaccttcac tgggacctaa aagatcctgc acaagctgtc gggagcgaag
     6181 aagaaatatt aacggaattc agaaaagtca gagaaggaat caaaagaaaa gttttagact
     6241 taaatcaacg tacatcgatc gtataaagaa gtattcaaaa tgatttttca agcactaaga
     6301 aacaatgtta aaaaaatagc tttccatatt ttacaaaatt gtgccttatt gccgacaaat
     6361 tgtctcttga acaccgttta ccagtagtca agacatcgta agcaactata aaaaattata
     6421 agaaactcaa aataaaagga tgtgccacaa ctttggccac atcctctttt tttgtattta
     6481 gttttctact tccaaataaa tagatagaat tattataaat ataaaggcag ttttttaatc
     6541 gctacttatt cataactaga taacaacgtt aagatttcta gcggatgatt ggattgcatc
     6601 aactgagcca tttgttctgg ctgcttttct agatagtgaa taacagaaaa tatttttttg
     6661 aactctgcat gtttcaaatc atttttcttt attgctaata gcagtacgat acgtatctgt
     6721 tccccgtgcc ataggactgg ttctttcatt gtagcaatag aaatcatcga atgcttcaca
     6781 tacagcggat taccgtgagg gattgttaca aatggtgcta ctctagtact ggagtgactg
     6841 tctctttcca agacagaatc gatgaattcc ggctccacat aatgatgttc cactaagacg
     6901 tttcccataa agtttaaaat atcggctggg tctgtccgtt caagttgagg aaagatcaga
     6961 aatggatgag taaagcttgc tagatcaaat gtttttttct tcttgatagg cacatgctcc
     7021 agcatatatt ttgtcaaata ggctagatca gtttctgtga tcattggtga gatctcgatt
     7081 actggaatgc ttatatgttt aaatggtaac gtagccaaga taaaatcaac agagggaaaa
     7141 tcttgtctct ttaattctgg cttatattca actagatcca taatcgttaa ttctggaagt
     7201 tctctgttca gccgtgcttc gagaaaagta gccatagctt ttgaatattc actaactaaa
     7261 accgtttgat atcttctact tttctgatgt ttgtgtcgct cgatcgctgc ttggaaatgg
     7321 atcgttaaat aagctgtctc ctcttgtgga acataaaaat tttccttttc aaaataatct
     7381 tctaaaatta actgtaaaac taagaaaagt tgtgtgtacg tactaaacac atttttcgtc
     7441 aatggattag aaatctgcaa accataatgg agtcgaaaat aagttgaaga taaatgagac
     7501 cttaaatttt gttttagtag ctgatcttct tttaatgaat agcctagaaa ctgttccact
     7561 tgttcgatca aatgatcagc aagtgcgcta gattcctttt gaaaacgtgt ggctgcttgt
     7621 gaatttgtaa aaagattggc gatacgcaaa gccagataat tgatttcatc aggagaaaat
     7681 tcaattggat agatggtggc tagttttgct aatatttgac tacttaactt ttgtgcttgg
     7741 gtgtgttcca cgacttcgtt ttcgtcttta cttaatttca ctttctggta ctgtttcatt
     7801 cgctcgagca taaagtagat gtgaatctcc acactagcca gtccattcgg ctgttctaaa
     7861 tggttttcat aaaaaacatc ttgtaatgta tgttggataa cttttaatgt atctttagcg
     7921 aagaattctt tcaacgacgg actttgtgga tcttctttct gcatatttcg taatgtctta
     7981 acaagcaact gtcttttttc ttgttcatcg cctttaagaa aagttcctag ttttgttttg
     8041 gatactagct gtaaatggtg atactcaaaa aagctttgca actctgtcaa ttctttacga
     8101 atcgtacgtt ttccaacata tagtttttct gaaagttctt caagactaaa tccgtctttt
     8161 gctactagca gatggaaaat caataactga cgaagctgtt ttttatccat ttctgtttga
     8221 gtctcttcat taagcgctcg tttcagttgt tccctttcgt gaggcagacc attcaacaag
     8281 atacctgtac ctttttttct ttcaaacatt aaaggcagat gtttgtctct caaccaagtt
     8341 tcaatggtat tcaaatcgct atgaatcgtt ctttctgaca catggaaatg ctctgctagc
     8401 ttttttgttg ttatataatt attgttctca cttaattgat agatcaaaga ttgctgacgc
     8461 tgattcataa tgtgcagaaa ctcccttcta aataaaaaat cgatcatgat aacacatcta
     8521 ttatgtctca tcacggtcga tttttcatct tatgttacat ttcgcttaat aattggtgaa
     8581 ctgttgtttt atctggcgct tccatcagtg cttgacggaa gtcatcatcc atcaatttac
     8641 gtgatagacg ttgcagtatt ttcaagtgca tatcaccttg gctgttttca ggtacagcaa
     8701 tcataaagat catatgtgca ggttttccat ctaaagaatg ccaatctacc ccagattgac
     8761 ttctggcaaa tgccactgtt ggtttaagaa cataagctga ttttccatgt ggaatagcaa
     8821 tccccatacc gattcccgtt gtactttcat gttctctatc atagatgact tctttaaatc
     8881 tggttttatc tgtgatcgcc gctgtttttt ctaaacgttg gactaaatct tcgattactc
     8941 cgtcttttgt tgttgctgtt tcacctaaaa cgattgcttc atctgacata atatccgtga
     9001 tagaatcaaa agtttcagtt ttcgtataaa catcacttgt ttcagtctct gatagatctg
     9061 ctactgtcac accatttgct gcagcaaccg cagtttgttg taatgtcggt ttaaggattc
     9121 ttaacattag cacggttaca gcaataccag caatcactgc tacaaaaaac atggctacgt
     9181 gatccactgc tcctaaaacc gctacgatcg gaccgccatg agctacatga tctgtcactc
     9241 ctgaaagcat cgcgatcaca cttcctgtca ttgccccgat tacaatgctt ggaatcaccc
     9301 gtagtggatc tgttgaagca aacggaatag cgccttctgt aatcccaaac agtcccattg
     9361 ctaaggacgc cttaccagct tctcgttctg ttttcgtaaa tttggttttt aaaatcaatg
     9421 atgccagccc caatgctaat ggagggatac agatagctac agcaattggc cccataatgg
     9481 aataattgcc ttctgcaatc aagccagatc cgaacaaaaa ggctacttta ttgaacggcc
     9541 cccccatatc aaaagcaatc atcgctccta agatcatagc tagaacaatt tcacttcctc
     9601 cttgcatccc tgctaaaaag tgagtcaatg aactaaatag aagagctact ggttctccaa
     9661 taacatagat aaacacaaaa ccaactgcca atgatcctaa aattgggata acaataattg
     9721 gcatgatcga ttgtaaagct ttcggtactc gcactttctt gattcctaaa gcaatgaatc
     9781 ctgctaaaaa tccagtgatg atcccgccta agaatcccgc attcgcatca ctaccatata
     9841 atgctccgtt tgccgctaac atcccaccaa caaatccagg aacaagtcct ggacgatctg
     9901 caatactttg cgcaataaat gcagatagaa ttggaaccat caaccccata gcgatacttc
     9961 cgatactatt catcgttgcc caaatcgttc cttctggtat cttgatccct tcaggtgtag
    10021 ctgttcctcc taatgttaaa gaaatcgcga tcaataaccc tcctgtaact acgaaaggta
    10081 ccatgtacga aacgccattc atcaaactct tatagatttt tttacctaaa ttttctgatt
    10141 cacttttatt ttcggaagaa ataattgcct ccgtactttt atagactggc gcttttcctg
    10201 ctaaaatatc tctcaccaac tcatctgcat ggtggattcc ttcttgcaca cctacggtta
    10261 tcaaaggttt accgccgaat cgtgatttat ctattttagt atctgctgcg atgattacac
    10321 cagctgcttc ttcgatatct cttgcagtca attcattttc aataccgatg gaaccatgtg
    10381 tttcgacttt tacctcggcg ccaactgctt tccccgcttt ctctaagttt tctgctgcca
    10441 tgtatgtatg ggcaatacca actggacagg atgtgattgc aataattttt ttcattttcc
    10501 taccgccttt ctacatttat agtatataaa aacggtttct ttttattaag cacaaaatga
    10561 ttccgtaata actgaaattc ttggaataaa tagaaatttc gctaaaaaaa ttgatatacg
    10621 atttattatg ttgaataaaa taatattgga aaatcttaca tttctgtact tctgcttacg
    10681 tacatcta
//
LOCUS       DADVXE010000083        10651 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.085, whole genome shotgun sequence.
ACCESSION   DADVXE010000083 DADVXE010000000
VERSION     DADVXE010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10651
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.085"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            33..656
                     /locus_tag="KB913_002475"
     CDS             33..656
                     /locus_tag="KB913_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820777.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /locus_tag="KB913_002476"
     CDS             1106..2155
                     /locus_tag="KB913_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6820778.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="KB913_002477"
     CDS             2152..3033
                     /locus_tag="KB913_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6820779.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="KB913_002478"
     CDS             3036..3806
                     /locus_tag="KB913_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6820780.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="KB913_002479"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="KB913_002479"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBB6820781.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="KB913_002480"
     CDS             5117..6280
                     /locus_tag="KB913_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6820782.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="KB913_002481"
     CDS             6397..6807
                     /locus_tag="KB913_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6820783.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="KB913_002482"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="KB913_002482"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6820784.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9380..9664
                     /locus_tag="KB913_002483"
     CDS             9380..9664
                     /locus_tag="KB913_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820785.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9824..10060
                     /locus_tag="KB913_002484"
     CDS             9824..10060
                     /locus_tag="KB913_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6820786.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10057..10455
                     /locus_tag="KB913_002485"
     CDS             10057..10455
                     /locus_tag="KB913_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBB6820787.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3722 a         1773 c         2253 g         2903 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     9661 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     9721 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     9781 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     9841 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     9901 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     9961 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
    10021 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
    10081 attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta
    10141 aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa
    10201 gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa
    10261 catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa
    10321 ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt
    10381 accactagtt cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa
    10441 accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa
    10501 ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga
    10561 aaatatggat taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg
    10621 aaatagtggt ttagaactag tgggctgatt t
//
LOCUS       DADVXE010000084        10400 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.086, whole genome shotgun sequence.
ACCESSION   DADVXE010000084 DADVXE010000000
VERSION     DADVXE010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.086"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            226..375
                     /locus_tag="KB913_002486"
     CDS             226..375
                     /locus_tag="KB913_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBB6820788.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            386..1900
                     /gene="dltA"
                     /locus_tag="KB913_002487"
     CDS             386..1900
                     /gene="dltA"
                     /locus_tag="KB913_002487"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBB6820789.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            1897..3102
                     /gene="dltB"
                     /locus_tag="KB913_002488"
     CDS             1897..3102
                     /gene="dltB"
                     /locus_tag="KB913_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBB6820790.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            3147..3380
                     /gene="dltC"
                     /locus_tag="KB913_002489"
     CDS             3147..3380
                     /gene="dltC"
                     /locus_tag="KB913_002489"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBB6820791.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            3383..4651
                     /gene="dltD"
                     /locus_tag="KB913_002490"
     CDS             3383..4651
                     /gene="dltD"
                     /locus_tag="KB913_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBB6820792.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            4792..5874
                     /locus_tag="KB913_002491"
     CDS             4792..5874
                     /locus_tag="KB913_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBB6820793.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            5874..6677
                     /locus_tag="KB913_002492"
     CDS             5874..6677
                     /locus_tag="KB913_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBB6820794.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            6747..7487
                     /locus_tag="KB913_002493"
     CDS             6747..7487
                     /locus_tag="KB913_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6820795.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            7498..8502
                     /locus_tag="KB913_002494"
     CDS             7498..8502
                     /locus_tag="KB913_002494"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBB6820796.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(8547..10391)
                     /locus_tag="KB913_002495"
     CDS             complement(8547..10391)
                     /locus_tag="KB913_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820797.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT         3347 a         1711 c         2099 g         3243 t
ORIGIN      
        1 ggaataagag gttgtgacac gatttttgtc acaacctctt tattttttat attttttaaa
       61 agtacgagaa attataaaga aaaaagcagt gatttgatgt gctattttta taaaagctat
      121 gtgacaaaac tgttagtaaa aaaacggttt ctgtaagcta gacacatgtt tctttttgtc
      181 aaaattagtt acactttgtg tgaggttata tgaggaggga atccaatgaa caaatggcgt
      241 tctaatccaa aattgaatta ttggggaaaa ttcatcattc gaacaatttt ttatagtgca
      301 gtactgctgt tcctgattta tctgtatcac tataaaaata ttcaaggagg aacttttatc
      361 tataacgaat tttaggagga agagtatgga aatcaaaacg attattgaag caatcgatga
      421 ttggggaata aatgaacctg atcgagttgc ttatcaggcg gatgagacgc atacttttgg
      481 tgaattgaaa caagcatcag acgcacttgc ttattattta gaaaaaaagg tagaaggcga
      541 tggaccaatt gtcgtttttg gcaatttgga gtttgaaatg attgtctcat ttctaggggt
      601 tgtcaaatct ggccatgcct atttgccgat tgaagagcat acacccaagg agcgtatcct
      661 atcgatcttt cgggtggcta aaccatctat ggtcatcagt atcggggact ggatagaaga
      721 tattccttcg gttcctgtca taacaaaaaa agaatttcaa gaaatcaaga agataccagt
      781 aggattttat cccagaaata gcgtaaaagg tacagaaaat ttttatatta tttttacttc
      841 tggtactact ggagaaccaa aaggcgtaca aatcagtcat gataatctag tcagctttgt
      901 tcaatggacg atggaagact ttgggatcaa gcctggtatg catttcttag cccaagcgcc
      961 attttctttt gatttatcgg tattttctat ttatcctgca ttagtttctg gcggaatgct
     1021 gaagccgtta aataaagcag ttgttcaaga ctttcgtcaa ttattcgcga cattgccagc
     1081 cttgaagttg aatgtgtggg tttctactcc atcatttatg gatatttgct tgatggaacc
     1141 tacattcaat ggagaaaatg tgccggaatt ggacatgttt ttattttgcg gagaagaatt
     1201 gacgaaaaaa actgcagaaa gtctacttga tcgattccca aatgcacgga tatataatac
     1261 ttacggtcca acagaagcaa ctgtagctat ttcaagtatt cagattgacc agcatgtact
     1321 agatagttat gaccgactac cgattggcta cgtaaaaaaa gacacgaaag tttctattgt
     1381 ccaagaaggt aaacctgttt caaaaggaga aacgggtgaa atcattattg caggaccaag
     1441 cgtatcaaaa ggttacctga acaatcccga aaagacagct gctgcgttct tttgtcaaaa
     1501 tgacttagca agttaccata caggggatgc aggtagacta gatgaatatg ggcttttatt
     1561 ttatgaagga cgtatggatc agcaggtcaa attacatgga taccggattg aactcgggga
     1621 tatcgaacat tatctgctcc aagacaaccg aatcaaacaa gctgtcgtcg taccaaaata
     1681 ccaaggaaca aaagtacagc agctggttgc ttttgtcgta ttagaaaaca aaacgaaaca
     1741 gccggatttt cagttgacta aatctatcaa agaacaatta ctagaagttg taatggatta
     1801 tatgattcct cagaagttcc attatgtcga tctgctgcct cagacagtta atggaaaaat
     1861 cgatcgaaaa aaattaacag ctgaggtgaa tcctgaatga tgttacctca tatgatccct
     1921 tatgcagagc cgttttattt ttttctttta gccattgcgc ttgtaccgat cgttctatct
     1981 ttattgatat gggaaaaaag attaccagtt tatcaatcag cagtgacact tttcttttta
     2041 tttgtcagct ttggaggtaa ttattggcaa cagggagcgg cgctgattgg gtatgttttg
     2101 tggcagacga tacttgtatg gggctatttt gtttatcggc aaaggaaaaa tcagacagga
     2161 tggttttttg ccgccgttat tttagcgata attccactgt ttttaacgaa agtgactcct
     2221 ttttttgaac atggaaaagc atcgttactt ggttttttag gaatctctta tttaaccttt
     2281 aaatctgtac aaatgatcat ggaaataaga gatggcatga tcaaaacata taagccattt
     2341 cgttatatcc agtttctgct gttctttcca acaatctctt ctggaccaat cgatcgctat
     2401 aggagatttg aaaaagatca gctccatccg cctgttcgtg ataaatatgt tgatcttttg
     2461 ggaaaaggcg tccaaaatat ttttgtcggt tttttatata aattcattat cggttattat
     2521 tttggtcaag tactgcttcc tgtagtggga cgcattgcct tacagcatgg tggtatttca
     2581 tgggcattag taggttatat gtacgtgtac agtatgtatt tgttttttga ttttgctggc
     2641 tatagcttat ttgcagtcgg tacaagctac atgatgggat atcagacacc aatcaatttc
     2701 aataaacctt ttttatcatg gaatatcaaa gaattctgga atcgttggca tatgacgctg
     2761 tccttttggt tccgtgatta tgtatatatg cgattgatgt tcttcatgat gaagaaaaaa
     2821 ttttttaaaa gcaagatcgt aatgtcaaat atcggttatt ttgctttgtt tcttctaatg
     2881 ggtatatggc atggattgac gtggtactac atcgtatatg gactgtatca tgcttgtctg
     2941 atctgtctga cagatgcatg gatccgattt aagaagaagc ataaagagca gttgccttct
     3001 aacaaattta cgcatggctt agccgtattt ttgacatttc aagcagtatg ttttagcttc
     3061 ctgatttttt caggattttt agataaactt ttttttagct aacgaatagt gacatattaa
     3121 tttatataac aaaggagaaa aggaaaatgg aagaacaaat tttatcaatc ttagaagaaa
     3181 taacaggaac agatgaagta agaaaaaatc gtgatattga tctatttgat gaagggttgc
     3241 ttgattcttt agcatctgtt caattattag tcgagctaga cggagagctg gatatccaag
     3301 tccctgtatc tgaattcgag cgagaggatt ggtgcacacc gaataaaatc attcaacaag
     3361 caactgcatt gaagggttga gtatgaaaaa gaaacttttt gctattttcg gcccggttgt
     3421 tttagctgtt ggcttactgt ttgtgttttt tacctcctcc tatcaagtag atatctctaa
     3481 tccagaaacg attagacgtg cctcttcttc catgtcagtg aacgtgttga aaggagatgc
     3541 gataaaaaat tatgcattat ctgaaaaaca atatattcct ttttttggct caagtgaatt
     3601 aagcagaatc agtccatttc atccgtctgt tctggcagaa aaataccagc gaaactatcg
     3661 tccatttttg ctgggagcac ccgggacaca atcgttaagc caatatatga tgatgcgttc
     3721 tgcaggagat gctatgaaaa acaagaaagt cgtctttatt atttctcctc agtggttcgt
     3781 taaaaatggt gtaaaaactg attactttaa tacgtattat tctgaacttc aaacatacga
     3841 ctggttgttt tcaatgaaga aagtaacgcc tgctgatcgc tatttagcta gaagattatt
     3901 aactttctca aaagtaaaag agaatgatac gttgacggcg attctgcaaa cgatcaaaaa
     3961 agggaagcta cctttacctg aatctttgaa tcagctgcgc agccaatgga acatgctgaa
     4021 gagagaggat gaagtattca gcaatattgg gttgaaagat cgacagcaaa aaatcgatca
     4081 tgagtcaaaa cgattaccaa aacaatacca agaaacagaa ttatccattt tagcaaatca
     4141 aattggagaa cgagaaacga cgaataatcc attcgggttg aaaaacgatt tttatacgca
     4201 tcgtatccga gcccacgagc cagagctcaa acagtcacaa aaaaattggg attatcgttt
     4261 ttcgccagaa ttttctgatt ttcagctggt cttggatcaa ttagcaaaaa accataacga
     4321 agtattgttc atcatcccac cggttaacga gaaatggagc gattataccg gactatctca
     4381 agaaatgtta caaggatttg ccaaaaagat caaatttcaa ttaaatagcc aaggattcaa
     4441 tcgaatagct gattttgtca atcaagcggg taccaactat tttatggaag acacgatcca
     4501 tctaggctgg aaaggctggt tggctgcaga tcaacagatc agaccgtttt tagaagaaaa
     4561 tcatattact gctagtaagt atcatcttga cgatgctttt tttagcaaat cttggcaaca
     4621 tcaaatacca gataaactac aattaaaata aagaaaacag gcgagtgttg ctcgcttgtt
     4681 ttctttattt ttgaatattc tgaataaaag ataaaaatac caagtttgcc tgaacaaaaa
     4741 tcataagcaa tggtataatc acaatatgaa tatagaaatg ggggaaaaca tttggataca
     4801 aaagaagaac agctacttat tgatttaact tctgcaaaag gagtacctgg aaatgaagaa
     4861 gaggtaagag aagtattcag agaatatgcc aaaccattcg ctgatgatat tttttatgac
     4921 ggtttaggca gtgtgattgc caaacatggt gctggcggag gccccaaggt ctttatttct
     4981 ggacatatgg acgaagttgg ttttatggta acaaaaataa ccgaaaaagg attcttggaa
     5041 ttccaaactc ttggaggttg gtgggggcaa gtcatgcttg ctcagcaagt tgaaatcaaa
     5101 acacgtgaag ggaaaatcgt ccacggtgtg attggttcca aaccaccaca tgttttaaca
     5161 cctcaagtaa gaaataaacc ttatgaaata aaggatatgt tcattgatat tggcgcatca
     5221 agccaagaag aagccaaaga gtggggcata cgtcctggag atatggtcac tccatatatt
     5281 gaatacaaac gaatgaatgg cagtaaatat ttactggcaa aagcatggga taatcgtatc
     5341 gggacagctg tttctctgcg agtattagag aatctatcta aagaagcaca cccaaatgtt
     5401 ttattcgcag gaagcgatgt gcaagaagaa gtaggcttgc gaggtgctcg aacaagtaca
     5461 caccttgtaa atcccgatat tgcttttgct ttagatactg gtacagcagg agacactcca
     5521 ggaatgacac caaaagaagc agattcgatt ttaggaaaag gcccacagat tttgattttt
     5581 gatgcatcta tgatcccgca taaaaaatta ttgaattttg ttattgatgt agcagaggaa
     5641 atggatattc cattccaata tacagtgatt tctggcggag gaactgatgc aggacaaatg
     5701 catttgacaa gagatggtgt tccgtctgta gccattaccg ttcctgttcg ttatctgcat
     5761 tcccatacat cagtgattca tgaagatgat tatttgaata cagtgaaact agtcacagaa
     5821 ttagtgaaac ggcttgatag tgaaacagtt gaaaaaattc ggagttatga ataatgaata
     5881 atagaatacc tatttctgaa tatcggaaaa aagcacgagt ttctttggaa aatcaatggg
     5941 gaatcaatac ttggcttgtt ttcttatcta taatatttac gagcgtcatc cagaactttt
     6001 ttgacggttt cagtcctttt ccggaagaaa gcatgcagca gcacttattg agttttctag
     6061 tcgataattt acttttattc gcattcaact atgcattgtt ttacattgcg ctagtagttg
     6121 tacggggtgg cagaccaaaa agtaaccttt tattttcagt tttccaaaga aagtattttg
     6181 gttcgatact tggcatcaat ttgatcaatt cagtcatcaa ctggctactc aacagtttaa
     6241 tctttctgcc catgttttta atcagcggag tgagtactta tatgcagctg cttttcagtt
     6301 caaatgcggt acctacgggt gtcatgccag aagattttct tgatatcagc tttgttttat
     6361 cgatgatagg gatgattttt gtttcagcac tcatcatgag tattgttggc ggtttattcc
     6421 aatttgctgc atggacaaag ttcgactatc ctgatttgtc ggttattcaa tgtttgaaat
     6481 atggctggtt tttattgaaa gatagaattg gtacgtatat tttgttgcag ctgtctttta
     6541 tcggctggta tttgctagga gcaatcgctt tgttcatcgg tcttttgtgg gtcattgttt
     6601 atgtgaatgt gtcagttgca gaattttatg aacaagcacg gattgaaaaa ggaggtccag
     6661 acgcctattt tacttagcat gtaagcagtt tattcatcaa aaaaataact tttgtggtag
     6721 gataaatctt tgagggggaa tgtacgatga aattaactgt tttaggatgc ttaggagcgt
     6781 atccttataa aaatcaaggg acaacaggtt atttgcttca atctgacggg ttcaatttgt
     6841 tgatcgatgc aggtagtgct acgctgatca aattacaaga acaccttgat ccacttgatc
     6901 tagatgctgt gatccttagc cattatcatc atgatcatat tgctgacctt ggtgtattac
     6961 agtattactg gcaacttcat cctaagagaa atccggagac attgctttca atttatggac
     7021 acacaaaaga ttccattcac tttgaagaat tgacgttgga aaatgtctca aaaggacatc
     7081 cttattttga agctgaagaa ttaaaaattg gtccttttct gattactttt atggaaacaa
     7141 tccatccagt agtatgttac gccatgcgta tcgtagaaga aacaacgggg aaagtattcg
     7201 tatttacagg tgattcaggt tatttggaaa gtttcgctga ttttgcgaaa gatgctgatt
     7261 tgtttctagc agatacctat ctttttgaag gaaatgaaca tcatcatgcc catttcactt
     7321 caaaagaagc tggagaactt gcgaaatcag ctaacgtaaa gaaacttgta cttacacacc
     7381 tacctcagtt tggtgattta gaacaattga aaaatgaagc gcaaaaggca gcaggcaaag
     7441 ggattgatat agaacttgct gcagttgaca aagtgtttaa catttaggag gaagaacatg
     7501 atttttgtac caaatgaaaa ccacgaccca agaatcaatt tagcaattga acaatatttg
     7561 ctgcaagaaa tgcctttaga tgaacctatt ttgctctttt atatcaatga accttcaatc
     7621 atcatcggca gaaaccaaaa tacgcttgaa gaaatcaatc gagattatgt ggaagaaaat
     7681 ggcattcatg ttgtccgtcg cttaagtgga ggcggagctg tctaccatga ttttggaaac
     7741 ctgaacttta gttttatcat gcctgatgat ggggattcat tccgtgactt tgcgaaagta
     7801 acacagccaa tcatccaagc acttcatgaa ttgggtgttg ctggggcgga attgaaaggc
     7861 cgaaatgatc tagtcattga tggcatgaaa ttttctggca acgcgatgta tgctaccaac
     7921 ggtcggatgt ttgctcatgg aacaattatg ttcgactctg atatcaatga agtagtcaat
     7981 gcattaaaag taaaaaaaga caaaatcgaa tcaaaaggaa tcaaatcgat ccgttctcgt
     8041 gtaacgaata tcaaaccatt tcttccagaa gaaaagcaaa aaatgacaac agaagaattt
     8101 cgtcaagaaa tcttgttgaa aattttcggc gtagagtcag tagaagaagt aaaaacgtac
     8161 gaattgactg atgaagattg gaaaaaaatc aatcgaatct ctgaggaata ttatcgaaat
     8221 tgggattgga attacgggaa gtctccagat ttcaatttct ctcgccaaaa acgtttttct
     8281 atcggttcga ttgaagtcca tttgaatgtc tcagaaggaa tgatcaaaga agcaaaaatc
     8341 tttggcgatt tcttcggact aggagatatc tctgacgtgg aaaaaaaatt ggttggacag
     8401 aaatatgata aagcatctct atcaaaaata gtcagccaaa ttgatgtgaa gaaatatttt
     8461 ggtgcgatag aaccagaaga attgcttacc ttactttatt gaaaataaaa aatagcggaa
     8521 tccacatata tggattccgc tattttttat acaggattcg ggtaatttcg agagagttga
     8581 acagtgatcc gatcaatgaa agtatctttt tcctgcgtta gtgttcctgt gtaacgatcc
     8641 gctacgtctt tcatcatcat taagtcaaaa cgttcctgat catctaattc ttctgtgatg
     8701 cctcgactaa ataggtttgt atcgtaatgt gcactatgtt cgcaacaaat gacgaaatgt
     8761 tcctcttgtt cgtgtatcga caaataaatt tttcgataca gtggattttc gatggcatga
     8821 gtttctctaa aggaatgctc taaagcgtgg atcaaaagtt gagccagatc gtcatcgttg
     8881 ataggaagtt cttcgggaag atctgcttgg aaggttatct gaatattccg tttggcagct
     8941 aacttctggt aacgcgctaa gataagattt gtcacctggt ggttgcaaaa agaacacagc
     9001 atttcgaaat tttttgcttc ttctaatatc ttttccacat agtttttagc ttttgtttgg
     9061 tccgtatgca ttaaatcttg cagattctcc atctcttgga caaattccag gcgaagtgta
     9121 tttacttctt ggatatgctg tcgaagctgc tcataatgtt gctccaacaa atcatttttg
     9181 atttttaaga aatctacttg tctccgatct ttgtcggtat ttaagatgtg atcgattaga
     9241 ttgtagctga taataacgat tagaatgata atatataaaa tcgtagacca attgatcgtt
     9301 gtttgataga tacctaatgc cgtttggatg taaatcaagc aatggataat ggctaccaag
     9361 acgatccaag gtgtacaagc tacataaaaa cggttattct tatatgcttc gccaatgcat
     9421 gcaagtgaag tgactaaagt gcttataaca ctagcaatat tagcaatcgg cattaattca
     9481 ggaagttctg caggagtaaa agttgcataa agcagaacgc cgataaaaat caaaagttgg
     9541 aacgtacaaa aaattccgta ccatttttta tagtaaaaca ttcggctcca atagtagcag
     9601 atgatgaaag ctgacgttaa gataataaat aaatgagata aaaaagaatg aacgaatggt
     9661 tcaaaaagaa taccacttaa aatatcttct gatacagctt caaatcctaa tgccaaagca
     9721 aagcaactta agagaataag tgagtattca agacgttttt gtttatacat caagtagatc
     9781 gtatagaaaa aggtccctat agcgataaaa acagcgatta tcatcgtcaa tacttgcggc
     9841 actgattgtg aataaataaa actaatcaat ggtccagttg ttcctagata aactttcggt
     9901 ggcagtccag catagttctg ataaggagat gagactgtaa gggtcaattt ttttccgata
     9961 taatttgctg gtaaatctat cacagccaat gagagtccgg gattgctttc ttcctgataa
    10021 tctttccgtt ggtataaaat cttttcgcct agatatacag taatccattg atggtttcct
    10081 ttgattagta aatttgcttc gtccaacggt ttttcaagtg tcgtttccat aatgaatgtt
    10141 tcgtctttat ccacggtagg aatcgtacga gtgtacttgc tgtcaaactt aaaatcagga
    10201 tcatcttttg tatagaaaac ccacgaatct tttatttctt tcatttgatt gctgtccgca
    10261 ggagaaaaaa taaaataaaa gaaataagca attcctgtta aaaataacaa tgataatata
    10321 atgattatgc tccactttat acgtaaataa aaagattctt ttttattata tatgttatta
    10381 aaaaaagaca taaaggtatt
//
LOCUS       DADVXE010000085        10084 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.087, whole genome shotgun sequence.
ACCESSION   DADVXE010000085 DADVXE010000000
VERSION     DADVXE010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10084
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.087"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(109..2229)
                     /locus_tag="KB913_002496"
     CDS             complement(109..2229)
                     /locus_tag="KB913_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6820798.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="KB913_002497"
     CDS             2459..3637
                     /locus_tag="KB913_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBB6820799.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="KB913_002498"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="KB913_002498"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBB6820800.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="KB913_002499"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="KB913_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBB6820801.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="KB913_002500"
     CDS             complement(4990..6243)
                     /locus_tag="KB913_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6820802.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="KB913_002501"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="KB913_002501"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBB6820803.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFISGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="KB913_002502"
     CDS             7821..9167
                     /locus_tag="KB913_002502"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBB6820804.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="KB913_002503"
     CDS             complement(9475..9861)
                     /locus_tag="KB913_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6820805.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(9910..>10084)
                     /locus_tag="KB913_002504"
     CDS             complement(9910..>10084)
                     /locus_tag="KB913_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBB6820806.1"
                     /translation="TVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQ
                     RRFEGTLRYSLGY"
BASE COUNT         3215 a         1839 c         2053 g         2977 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt atttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttattata cccgtggtgc
     9901 tagttaattt taatatccta aagaatatct caaagttcct tcaaaacgtc gttgtgctcg
     9961 acttaataga acactgtaag ccagtaatat gctttcaaat ctactctcta gccctttaac
    10021 agaacgtgag ttgaaatttt gacaacctaa tttttctaag gaagaaaaaa cagtctcaac
    10081 tgtt
//
LOCUS       DADVXE010000086        10071 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.088, whole genome shotgun sequence.
ACCESSION   DADVXE010000086 DADVXE010000000
VERSION     DADVXE010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10071
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.088"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(16..168)
                     /locus_tag="KB913_002505"
     CDS             complement(16..168)
                     /locus_tag="KB913_002505"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBB6820807.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(359..1237)
                     /locus_tag="KB913_002506"
     CDS             complement(359..1237)
                     /locus_tag="KB913_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6820808.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(1276..2394)
                     /locus_tag="KB913_002507"
     CDS             complement(1276..2394)
                     /locus_tag="KB913_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBB6820809.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(2391..4490)
                     /locus_tag="KB913_002508"
     CDS             complement(2391..4490)
                     /locus_tag="KB913_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBB6820810.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(4541..5362)
                     /locus_tag="KB913_002509"
     CDS             complement(4541..5362)
                     /locus_tag="KB913_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6820811.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(5359..6168)
                     /locus_tag="KB913_002510"
     CDS             complement(5359..6168)
                     /locus_tag="KB913_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6820812.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(6189..6683)
                     /locus_tag="KB913_002511"
     CDS             complement(6189..6683)
                     /locus_tag="KB913_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6820813.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(6695..7183)
                     /locus_tag="KB913_002512"
     CDS             complement(6695..7183)
                     /locus_tag="KB913_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6820814.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(7260..9956)
                     /locus_tag="KB913_002513"
     CDS             complement(7260..9956)
                     /locus_tag="KB913_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6820815.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
BASE COUNT         3061 a         2267 c         1658 g         3085 t
ORIGIN      
        1 ggctgaaaaa atctatcacc aaaaaaattc aaacattaag ccaaggatta tgaagtcaac
       61 atttcgaaaa atgaacatac attggtaagc aactataact attaccacag acataaagta
      121 acacaatata ttactattta agtgtacgcc accagtgaat atcctcaagg tatacagcgc
      181 acaacaaaaa gaaaaaagga aacgcagaag catttccttt cagtgattta atgaaaacaa
      241 cacgatttga cttagagcct ttttatttga attcattttc gctttatcca acttcatttg
      301 atcatttgat tactcggtta aatacttttg acatgagtat caatgaaaca ttcattaatt
      361 atggttgctt atttcttacc gcttttctgg ccaatgctaa tccgccgatt attccggcat
      421 tatcacctaa ttcgggcgta ataatgtagc tatcaattgg tggtatttca acatatccat
      481 ttataagctc aacaaattta tcctgaactt ttttcttcat gtgttcttgt ttcattacac
      541 caccgccaaa aataattcta tctggcgaaa acatcagtgt tgtattgtat gcacattggg
      601 caaggtaaaa ggcttcaatc tgccaaaacg aatcgtcagc caataaattc tggcctttta
      661 cacccaaccg tttttcaatc gctggtcctg ctgccatccc ctctaaacaa tcttggtgga
      721 agggacagtt tcctgaaaaa ttgtcctttg gatgtcgctt gatcaacata tgccccattt
      781 ccggatgact gaacccttcc acgaaagtcc cattgaacaa ggcaccacct ccgatacctg
      841 ttcccacagt gaagtatgca acacctgcta accctttgcc agaaccagca acatattcac
      901 catagcaagc cgcattgaca tctgttgtcc attcaatcgg aatattgaaa tattgcttta
      961 gcgttcctac aaaattgaaa ttttgccaag caagttttgg tgttgatgtg atatgaccga
     1021 aactcgttga tttgcattga atatcaattg gaccaaagca gccgaccccg atgcctgcca
     1081 attgttcctt aaaaggttta aaaaaatcaa tgacctgctt cattgtttca actggagttg
     1141 ttgtgggaaa actgactctt tccaaaatcg ttaattcctc agtaccgact gcacagacaa
     1201 atttagtccc tccagcttca attgccccat atatcatcat aggttcctcc cttcgaatat
     1261 gtgaaaaaca cttcattaac gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt
     1321 tcctgaagct tctgttgaat accagtaagc gacactagca acatcgtctt gccgctcaaa
     1381 taagcgaaca tcatcgttgc cgatttgttg taaagtgacc gataaatctt cggtaaaaca
     1441 gatggggtct tgaagatgcc aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa
     1501 ggcatgaacg gcattcaatt ttcccgtttc aaaacgatct cttgtggcat ctctatttga
     1561 ttggtaagga taccctaaaa aggctgttga atagtttttc gcatgtggac gtccgaactc
     1621 atcgtactca tgaaaggccc acgccccgcc aaaataatct tctgaacctg ttgaggttac
     1681 ggtcggatac tcactatccc catcaatgta gaatttaaac tcgccttcgc cccaccaata
     1741 acgttctagg caggtaagcg caaggtaagt acccacgtaa tagccttgac cctttaatcg
     1801 atcaattaac ttataatcct cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg
     1861 aaaatatagg ctattttctt ccaattcgtc caccaaagcg taatttatcg tataaaaaaa
     1921 tgaggacata tccttcggat gtaaattctc gatcgtaatt ttagcggatg tttggaaagg
     1981 catttcgaaa taggaattaa agccccctgt aggattaacc actatcggca acgagttcac
     2041 ctcgcaacgc tctccaaacc cattacaaaa gaaatcccct aaaggacttt caacagcagg
     2101 gctatccgac ccatcccaat aaattcttaa gattaaatca cgtaaaacaa aactgccaaa
     2161 ttctgttcga tcacgaatcg tcatccacat atgacgaatt attcccgttc cagtaatatc
     2221 cgcaatcaca gtttcttcac cagaagtcag cggaattgcg ccacgacctt tgcggcttgg
     2281 tcctagctcg cttggcaaca tcgcagcttt acctttctcg cctgttggat tttcgggagt
     2341 gattgctcga ctctggattt ttttaaattg ggtaatattt tttagtatac tcatcttttt
     2401 ctcctttgaa tgtgaatcgt ttttcccttt tctacgtgaa gaattttttt cgtatcactt
     2461 attttcaatg gcttttctga caaatttgaa atactcaact cggattgcgt acattcaatc
     2521 gaaatgaagg cttgaccgaa cttcaaattc ttccaagaaa acgttaaatt atcaacagga
     2581 tcaatttgca atactccttt tttgaatttc aatccgaaat attgactgat cattaggctg
     2641 acaaaaagac ccgatgccca gccgcatttg ccgcagccaa agtctcgcac gacttctcct
     2701 tgttgagcct ctaagcgata cggccaccac caccacgaac cgtctaaatc tgccaaacaa
     2761 attagttctt ctaatcgggt tacgaaagct tgagggttgt gcagctcgct cattaaaaca
     2821 gtgataaagc caggaaaagt ggcgccggat tctaatcccc aagtgatgcc tttgatttcc
     2881 tcgctatagg ttggattgaa agaactagca gaaaaggcca tggtgttctg atataaatga
     2941 tctttattat ctaaaaattg ataaaaaggc atcaacgtag tgtctgattc ttctccatca
     3001 tgcatcaata aattaatttt tccatccaca atcacatcac ttaaaaagat taacccttgc
     3061 tcaagaatcg gtttttgata gtgcttcact gaataggttg ttttctcctc atcaccgatt
     3121 ccctccaaaa attgctcacc aaaaggacca tcgatagtca tttgtttaca aattgattcc
     3181 tttagtttac aggcaatgtt tttgtatcgc ttgctaagac tcagttgttc tagggcttca
     3241 aaaatttctg caagtccaat acaggccttc caaagacaaa gattgctgcc ggtatgatac
     3301 tttccaagtg caaaggcgtc tgataaccaa acagatggaa aaagcattgg ttcccctgac
     3361 cgacgttgag ctaatatgtc ctcaataatt cttgaagcat tcagtagaac ctgcggacac
     3421 cgctcaaaga attttgtatc cccagtatgt tcaaaataaa gactagccag taacgcactg
     3481 gataacgaat tactcagaga atgattgata cctcctgtaa attttgaacc aggaaactta
     3541 acgccatatt gatcaaacca tagaaccgtt ttttgacata actccggttc aaacatggtg
     3601 aatggcaatg atgcgtaata catatcctta ttccaaattc gattagtagc aggatagctg
     3661 ccccaattgc tgccgacgac ctgtccctgt cgattcatac cgaaactaga aaagctttga
     3721 taaagtgcac gacgatagag atggacaact ctatcgtttg gcattgacag ctgcccaaat
     3781 agctgagcaa aatagttcaa tgtttccttc agccattttt cgatatcaga ttcctgaaaa
     3841 gtcattactt cttcaaaagc atttgggtcc acaaaagcaa tggcgaagct tgccacttcc
     3901 tgttgtgcga tcgtgtcctt atttcctttt tgagaaatca acacattttg ctgatccgaa
     3961 tacttctctt gatacgaagg cacatctttc actgaaactt gaaggctttc gtgtgtttca
     4021 ttcacaatgt aaacctgttg aacaagcata cttaaacgct tattagccag tatgggagca
     4081 aaggatacta caatgacctt aaacgtcgaa taatgatgaa tatatctagg caaacagtct
     4141 tgaatcacat cgacttcaat acgatgatcc gattctgaca aatggtagac aatcccgttt
     4201 acttcaacct ttaaggataa cgaattggtt tgagagagct gtttattgac ccaaacacct
     4261 ggtttttcct cagttagtaa attttctcga taaaaggtca acgtttgaat cgtcccgcaa
     4321 acatcaaggt ttgctaatgt cttttgatta cttacatcga aggtcaatcc ctttacatca
     4381 ggaatattcc gatagtagct gtattcgttt gaagtagtca catttccgtc gtttaactca
     4441 gcattaaaaa atgggtgttt gggtgaataa attacttcat taatagtcat cttttccctc
     4501 cttgctaaaa aaactgcagc ctagtagctg cagcttccta ctatgcgatt ccaagtaatg
     4561 acaataaaat tcccaagacg accattccaa aaataatttt gatgacgccg acttttttat
     4621 ctagtaattt gaaacagctc aatgttacca ataacggtac aattccttta aaaatactat
     4681 cgaggatttc ttggacattc attagttctt cgcccttcat tgaaaagctc aaaacggtat
     4741 tgaatttgac catactgatc gtcattgcac ctaccatgat cagacccaag atactagcag
     4801 cttttgtcag aatttcaatt aacccgttcg catacagctt ttcaatatat ttagagccta
     4861 atgaatagcc taaaacgccg ccatagtatc gcatcaagta attaggtata ttgaacataa
     4921 ctaaaaagat aattggtgcc aaaatatttc cggcattggc taagttgatc gctagtcccg
     4981 cggtaacgac acgccaaact ccccagaaca atgaatcgcc aattccagcc aatggtccca
     5041 tcaaactcgt tttgatcgcg ttgatacttt ccacgtcaaa accagctttt tcagaatttt
     5101 ccttctccat cgatgccgca atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa
     5161 aatactgtgt atgacgttcc agcgccgcag ctcgatcttc ttcacttttg tagaaatgat
     5221 taatgaaggg catcatagaa taggcgaaac caccgccgcc catcgtcacc ggattcaccg
     5281 aagcatacat agtcatcgag cgccaaaaca tcttccgaac caattttttc tcatctttag
     5341 aaattccatc agctaatttc attgaaagaa atcctcctct tcttggtcaa gcgttgcatt
     5401 tacagcagca tcgctttgaa ctgcatgaac agatatattt tttagttgta gatctctttg
     5461 ggctataaca attgcaataa tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag
     5521 atacgccata acaacggccc caaagaaaaa ccacacagca atatttttac tccaaagcat
     5581 ccgtaacagc atcgccatcc caactgccgg cagcagattt ccagcgactg ttaatccgtt
     5641 catgatgacc tctggaatat tatccaagac gcttttgaca acatctgctc caaataaaac
     5701 ggcaaagaat ggaataagag cataaagcgc atagtggaca aaccacataa agaagtgcag
     5761 attgatgatt cctttttgat caccagattt tgcaaatttg aaaaatttag cagccatcgg
     5821 tccacataca aaagaaaaaa tcatattcat taactgtaat cctaatactg ctagtggaaa
     5881 gacaatggga ataatcgcat ccacgtttcc tcccattttg attgcgaacg ctgtagccag
     5941 cccagcagcc aaagaaggct ccgccgtact agagattccg atattgacga cacccataaa
     6001 gatggcttct agtgacgccc cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc
     6061 tgctaacgga gcaacaacaa tcggacgact cagcatggac atcccgaaca tttcatgtcc
     6121 agcaactcca ataaaaacgg ccaaagcgac tacaaatgca tcatacataa tttttctcct
     6181 tcctttttct aaaaatcact caaaatagag atagctgaac gtttttccat cgccggtgta
     6241 ggctgaaaaa cggtatctgg ataaagttca actaattctt ttaagtcttg aatttctgac
     6301 gtcgttaaca tcacttcctt tgataaggtt ttcttatctt ccgatggcgg tgtcattttc
     6361 ccagcattcc ccacgttcat taattcgatt tccgttggga aagctttcgc aacttttacc
     6421 gcatctttga cattagggac taaaaccatc aagcgcatgt ccttcgcccg cggatctttt
     6481 aacaaatgaa tcgcgtcatc aactgtttta ataatgactt tgacattcga tggtgcagcc
     6541 atcttcaatg tcatcttttg aatatcgttg gtagccgcct catcgcttgc tactactaac
     6601 ccggttaaat ttagactctt tgtccaagtc atcgctactt gtccatgaat taatcgttca
     6661 tcaattcgca ctgctttaat catttttctt cctcctaaaa aaaatcttcc tcttcattta
     6721 ctacatgtac ctcatcaaga atggtcatct ttaattcctg ttggcattta tttaccagtt
     6781 cctgaatatc ctcctttgtt aattccttgg ttgccaatac tatttcgagc agaattggca
     6841 gattaaagcc agacaaaata gttacagcaa tctctttctc caaaaaggtt ttggtaatct
     6901 tctgattgac acttccgcca aataaatcgg taaaaacaaa aatctgatcc tgctcgttca
     6961 cctggtttac aaatacattc aactcctgtt caaaatcaca ctcatccaca taagcattaa
     7021 tcaccgtaat ctcttgaacc ttccccgtca gtaattgaat actgctaaga aagcctgaag
     7081 ctaagtgacc gtgagtcgct attagaattt tcttcatatg gttaattcct ttctttctgt
     7141 tcacttttat ataagcaatt cctgtgccaa cttttaaaaa cattggttta atcacgttaa
     7201 ttcacattaa aaaaagtgtc taacctaaaa aaaacagatt agacactttt ttagacactt
     7261 tatttttgaa tatacggtcc taataattca tagagcagcg aaagctcata agcattgact
     7321 ttaaaattat atttcatctc cattgattga aaaatacttc tagaaacata ataaaattca
     7381 tcttcatctg gtttcaaatc ataattcggt tcttcagatt tttctgtccg agccaagaat
     7441 aaacgttcca tcatcaatgc cgtatgcata tagagattta gttttacacg gccatttaaa
     7501 gtgaaatgat agtaattttc atatttagaa atgactgttt ccacttcact catcacgatc
     7561 gttgggttca gaaagttcaa acggtccgca attccttcca acgaaaagaa ttttactagc
     7621 tcctgaatca agcggttaaa ttctgccggc ttcatttcag gactcaaaat atgctccaaa
     7681 ttggctgctc catcaccgtc taagatgtca taaacattaa tattaggaat tgaaaaggaa
     7741 cgtggaagat ccgaagtcgt gatgaccaat tttgtcttgt caaaataagt ttcatcattt
     7801 tggtcgatta attcacgtag ttctctgtag tccttcgtga aaacttcgat ggattcatcc
     7861 gataaatgat gacgaaaaac atctttcaat ttgtccgaaa tccccaaacc cgacatacag
     7921 gaaatgataa tgttgctact ttgagaaaag ccttcaaagt attgaacatt gattgaatac
     7981 ttgtctgctg catcctccgc aatctgttta aatggcgcat tcatcgtcat cttcaagcca
     8041 atatcaagtg caatggaagt cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg
     8101 ttcttgatct gtgtgtaaat ttgatttaaa gagcccatat ctacgatcag cactagacta
     8161 tctgtattca cttgccgttt cacgaaattc cttgtcgatt cgacaatctc tgacacatta
     8221 ctctctactg gcatatccaa cgcttcaaaa acataattgc cgcataattg attcactact
     8281 gcttgaatgc tgctagccgt actatctccg tgagcaagca acaggccctt cagctcgatg
     8341 gattcatcta cataatcaga taaagtcacg acaataagca gtcttagaaa gttctcgtcc
     8401 ttttctgaga gcggtggtaa atgctccaag aactgattac ataagtaagt cgtccgaggt
     8461 agatttgcag ctaatgtacg atttatcccg gttaagtctg tcttatagct tggggaaatg
     8521 acataggatc tgctaataat ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt
     8581 cctaaaacgg atacccagac ctttctaaac atctgaatca tcaattttct actcattgat
     8641 aaaaaagaat ccttatcaat gtgatgcacc aaatgctgta cttcattctt tatcgaagaa
     8701 aaattttcat tgaaattacc ttcatttatc agctgagtaa ttttttccaa aatcgaatca
     8761 taatcaaacg gtttgattcg atccgttttt atcttttgat ttttctttat caataaacta
     8821 gcaatcggca agctttctac ttcggattcc agcatattta actgaatcaa gatctcattt
     8881 ttcccaatcg ttaatggttc ttcttgtgtt cgactataca catccgcaca actgatttta
     8941 atgatattct tcagcttacc aatattccca ctaaagggat gagataacat taaagacaag
     9001 gcttctcttg aaacaataat atctttttgt aaaacatccg cttcattttg aaaaaataat
     9061 tgaatcagct ctaatcgttc tcgaatgggg cgatcttcaa aagttggcaa cataacacta
     9121 atttgaatac gccgatcaaa ggtgtctaat aaataatttt cacctttttc cgtcgtggcg
     9181 aaaataaaac gaaccttagc agaatgccaa tttacatttt caccgactgg acgatagttt
     9241 ccagtatcaa taaatagaaa gagcttttct tgattttctt tcgataggcg atggacctca
     9301 tcgagaaaaa gatagccgtt gttggccgtt gccaataaac catcggtatc cttttcagcc
     9361 cccgtaaagg cccccttctt gtatccaaac agtgttgccg aaagcagttc gggattgtcc
     9421 gcataatcgg cacagtttaa gatagcaaat ggtgcatctt tttcaataat ttgctcatgg
     9481 atagcgtatt caaaaatttt tgtggctaaa aaactttttc caacacccgt ggctccattt
     9541 attaatacac tgagtccgtt aggcggatat ttgacagcgg ctatacattt ttgaatgacc
     9601 tctctcagac ttccgtcatg accaactaca gaatgaaagg cttcgtttat ttgctccgta
     9661 ttatctacaa ccgcatattc atctaaaggc ttccacaaaa caggctttcc cggtaatttc
     9721 tcgacctttt tatcttccac taatctcgtc aaataatggc tggcattctg acgagagata
     9781 cctagattct tcgaaatttt ctcggcagtg acagaagaca tattccctgt tagtcgtatc
     9841 agctcatcaa aaactcgatc tttagcgctc tttttcattt tttcctccag tttaatgtgt
     9901 ctaaaagcat aataaactat cggctgcaat atgtctattc tatatttgta ttccaatttt
     9961 tactttgaaa cacaaatagt cgaatatttg cctcagatat ctgacaaaat aatttatcta
    10021 ccaatttagt ttttatctaa tatgattttt atgttttttc atagctacaa a
//
LOCUS       DADVXE010000087         9718 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.090, whole genome shotgun sequence.
ACCESSION   DADVXE010000087 DADVXE010000000
VERSION     DADVXE010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.090"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            89..1078
                     /locus_tag="KB913_002514"
     CDS             89..1078
                     /locus_tag="KB913_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6820816.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1060..1521
                     /locus_tag="KB913_002515"
     CDS             1060..1521
                     /locus_tag="KB913_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBB6820817.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1571..2035
                     /locus_tag="KB913_002516"
     CDS             1571..2035
                     /locus_tag="KB913_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6820818.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2049..2798
                     /locus_tag="KB913_002517"
     CDS             2049..2798
                     /locus_tag="KB913_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6820819.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2798..3628
                     /locus_tag="KB913_002518"
     CDS             2798..3628
                     /locus_tag="KB913_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6820820.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3628..4275
                     /locus_tag="KB913_002519"
     CDS             3628..4275
                     /locus_tag="KB913_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6820821.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4373..5149)
                     /locus_tag="KB913_002520"
     CDS             complement(4373..5149)
                     /locus_tag="KB913_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6820822.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5293..6252
                     /locus_tag="KB913_002521"
     CDS             5293..6252
                     /locus_tag="KB913_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6820823.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLEVDTIVGVKHKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHLFK
                     SMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            6369..6677
                     /locus_tag="KB913_002522"
     CDS             6369..6677
                     /locus_tag="KB913_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBB6820824.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQFHLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEARKEYLISPKLRLKSVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            6704..7003
                     /locus_tag="KB913_002523"
     CDS             6704..7003
                     /locus_tag="KB913_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HBB6820825.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGMLPEDVT
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTNE"
     gene            7177..7728
                     /locus_tag="KB913_002524"
     CDS             7177..7728
                     /locus_tag="KB913_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HBB6820826.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFPRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            7874..8167
                     /locus_tag="KB913_002525"
     CDS             7874..8167
                     /locus_tag="KB913_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820827.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            8160..8456
                     /locus_tag="KB913_002526"
     CDS             8160..8456
                     /locus_tag="KB913_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820828.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHAGYRHSWERIN"
     gene            8527..9531
                     /locus_tag="KB913_002527"
     CDS             8527..9531
                     /locus_tag="KB913_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBB6820829.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKETVETDTTIEAKKSKTQS
                     TEQTTTEMKQSVEASTSESSIIESSSEEVKNTLWDSEKSTQLAIFVPQWGKTLGQEYK
                     SYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVET
                     GEYLGQHVYFFGFQNGQPKVYLTQQNQGNDKNYMYFNETQNQQLKQGFIDIVNGQTPQ
                     TPVVEESTQQATTTTTQSTSSSAISSWEAAKETVLNNKALWLYDSPDKNASNTNLIST
                     NEYMKDLMQDENGSYYSINIVTDDNGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK
                     "
BASE COUNT         3449 a         1382 c         1815 g         3072 t
ORIGIN      
        1 atttttttga aaaatagtat tgcaaaataa agcaatttca tagataatag gtattgtaaa
       61 gttatatgac tttataatac ttattagagt gagggataaa gaaatgagac aactacacaa
      121 agaacagatt gaaacagcaa tggcagcgtt aaaggaaaag acaattgatc atgtatattt
      181 tacagcatgt gggggttcac aagccgtttt aatggctggt caatatctat ttgataaaga
      241 attaactgta ccttgtcatg tttatactgc taacgaattt aactatgcta taccaaaagg
      301 attatctgaa aattctttag ttatcacttg ttcccattct ggcacaacac cagaaactgt
      361 agaagcaaca aaaaaagcaa gagaatttgg agcaatgact atttgtttat ctaatgaaga
      421 aggatctcct ctatgggaag cagctgaata tcctgttcac tatgattggg gtaaagatgt
      481 tgatgctagt gatttaaata aaggaattct ttatggttta ttatttaata ttttacttgt
      541 tttagatggc tctaaaaaat gggaaacttg cttgaatgaa tttgataagt taaatgatct
      601 tgttattgct gaaaagagca aatttgaaat aactgctaaa gaatggggta aaaaccaaaa
      661 acgagataaa attatttaca caattggtag cggtatcaat tacggagaaa tttactccac
      721 agcagcttgc tggttcatgg aaatgcaatg gattaattct aatgctattc attctgggga
      781 atttttccat ggtccttttg aaatcactga ttatgatgta ccattcatct tagtgaaaag
      841 tattggagat acaagatttt tagatcaacg ggtagaagac ttcactaaaa aattcagtaa
      901 taaattaatg gttttagacc aagctgattt tgacttagaa tctatagata gtgtagcgaa
      961 agaatatatt gcagctgtac ttagtggcgt tgttattcgc caaatggtag aagcgattgc
     1021 ttttgaaaga ggccattcct tagatgttag acgctatatg tggcaaatga aatattaatt
     1081 aataggaggt tgcaaaagat ggcaaatcaa ttatttcaca ttgtgattac aacacattct
     1141 accctttgtg agggttattt aaaggcaaca aaattaattt taatgaatga cgccacaggt
     1201 attagtgctg ttccatttaa agaaaatact agtccagatg attttgagga gagtatgaaa
     1261 gaaataatta gtcagcatca tttgcaacct ctaattattt taacggattt aattggagga
     1321 acacctaata atgtttctat taaacagttg aacaacaata gaattcaaat tattgctggg
     1381 attaatttac ctcttttact ggagttatta atggcccagt cagctggtaa atctatagaa
     1441 gaaatagatt ttaaggaatt actgaataac tctcaaaaaa gtatggttca tattaattcg
     1501 cttttaaaag atgtcagtta aggtggcaat ttctattcta taaattttaa aaattgaagg
     1561 aggaaataga atgattaaat tagtgcgtgt agaccacaga ttacttcatg gacaagtaat
     1621 attttcttgg actaaacagt atgatattaa ccatattatt gtggctgata acaaagttcc
     1681 aggagatcca atgtctgtga tggctttgac aattgctaaa cctgctgatt gcaaattaga
     1741 cattgttaaa attagtgatg ttaaagggat tatggaaaca tccccaaatg ataattacat
     1801 gattttaatt aaaggaccta aggaagcttt tgaattagtt caaaatttac cagaaattaa
     1861 agaaattaat tttggcggtg tgtctaagaa aagcgagtcc aaacaatatg gaaaggcagt
     1921 ctttttaact cctgaagaat tagaagccac aaaaaaaatt cttgatcaag aagtgaaaat
     1981 atttgtgcaa caagtcccat cttcaagtat tgaaaatgta gattttagta agtaaggggg
     2041 gaaaataaat gttattaaaa gccattttat taggtttagt tggtgtggta gctgttattg
     2101 actccaggtt aattggtcga caaaatattg gtagaccact aattttgagt acacttgccg
     2161 gacttgtgct aggtgacttg catacaggga ttgttcttgg ggcatcttta gaattaattt
     2221 ctatgggatt cgtctcaatt ggggcggctg gacctcctaa tatgcaactt ggtagtatta
     2281 ttgccactgc ttttgcaatt ttaactaata gtagtacaga aacagcctta acaatagcta
     2341 tcccagtggc tgtagctggt gaatttatga gtattatcat gcgcatgata attgctcaat
     2401 ttggacatgc tgcagataaa gccattgaaa ataataaatt tagaaaagct caaattattc
     2461 atatttattg gtcatttatt tttaatgctt ttgtttactt tattccaatc tttttaacag
     2521 tatattttgg tgctgacgtt gtggcagatt tagtagataa aattccagaa atgattacag
     2581 acgccttgac tgtctctgga aatatgcttt ccgcattagg gtttgcaatg ctattaagca
     2641 caatgttgag taaaaaatta tatccttact ttatttttgg attctttatt gttgcctatt
     2701 caggtctttc actaattggc gtgacaattt ttgcagctct gattgccttt gtaatggatc
     2761 aagttaaata tggaaaaaga gaagaggcgc atggttaatg gaaaatagta cagaaaaaaa
     2821 acgtttaatc acaaaaaaag atcttaataa gatgtgtctt cgttcatgga caatcatgtg
     2881 ttcgtggaat tatgaaagac aaatgcatat gggatttatg tatgggatgg cgccaatttt
     2941 aaataaagtt tataaaaatg atgaagagaa aaaaagagaa gcttatactc gtcatatggc
     3001 attttttaac tgtacgcctc aaatgacttc atttattatg ggactttgtg cttctatgga
     3061 agaacaaaat gctcaagcag aagaaggaaa ctttaatact gaatctatct ccatgattaa
     3121 aaccagttta atgggtcctt ttgctggaat tggtgattca tttttccaag gtactttaag
     3181 aattattaca tttgggattg gattgtcttt tgctaagcaa ggtagtattt taggaccgat
     3241 tttagctgtt ggcctttttg ctataccttc tattttagct gttttttacg gcggtaaatt
     3301 aggatatgag tctggcaata aataccttac taaattgtat caagaaggtc ttatggatcg
     3361 agtaatgcaa tttgcttcta tcattggttt ggctgtagta ggtggaatgg tggctagcat
     3421 ggtgccaatt gtcacccctt taaaattcac tacaggggga acagaacttg ttttacaaga
     3481 cttacttgat tccattattc ctggattatt accacttgta tgtactttgg gaatatataa
     3541 attgattaag aaaaatgtta gtacaaatat gctcttatta ggttgtattt tggcagggtt
     3601 tgttttaagt ataataggta tcttataatg attaaggctc taatttttga tatggacgga
     3661 gttttaattg atagcgagat tatgtatcaa aagtgggtat ttaatttttt aaaacaagaa
     3721 aatttaagct atcctttgta ttcttatcaa aaaaagattg gaactacagc aagtattttt
     3781 gatgatatag aaaagtacaa tgagggatgt aacagtttag aattgaaggg aaaatttact
     3841 aaatattgga aatcgcaaaa gattgattac ttggatattt ttcctaatat actaattgaa
     3901 cagcttgaat ggttaaaaaa gaaaaaaata aaaatggcaa ttgcttcttc cagtccaatg
     3961 gatactataa atgaagttgt taccacttgt aaaatagagt catattttga ttgtttaatt
     4021 agcggaagag atttgccaga aagtaaacct aatcctacta tattccttaa agcttcagaa
     4081 cagctcagaa ttccagttga agaatgtctg gtgatagaag attcttataa tggtataaaa
     4141 gctggtaaaa gagcaaatat gaaggttctt gcaattaaag ataaacgttt ttctcaagat
     4201 gtaagtctag cagatgatgt tatttacgat attaaatatc tgcgacaaga agtacaggtg
     4261 aaatttggaa tataaataag ttttttgatg tatttagaga atattagtaa aaataaaaat
     4321 catgcccaaa tctaatcaaa attgattgct ttgggtatga tttcttttaa tatcaatcta
     4381 ttactttagg atctgaatca tttttatgca ccgtatctaa agtgatattt tctgtgactt
     4441 caataacata actaattcta tcacaacgaa ctgtggattg agaataatga aatggttgat
     4501 tatttttatc tttgccaacc ttttctaaaa taaatagcgg atctcctact atacattgca
     4561 ataagtcgga aagctcaggt gttgcagata aaccgtttat ttccataata gagctcgtag
     4621 ctttgacatc atagtcatct tctagaagtt tatataatga agtatattgg ctaccttttt
     4681 caaataaagt tggaaatttt tcttctgatg cgaaaaaatt atcaattccc atcggggcac
     4741 cgtcttccca cattaaacgt ttaatattgt aaactctatc agttacattg atttgtaatt
     4801 tattagctaa aaactcatca gcctttataa ttttagaatg taaaacagta tatctaattt
     4861 tatgtcctcg ggtagaaaga gaatcgctaa atccatgaac tccagctaat tttaaacttt
     4921 cttttttttg agttacaaag gtccctttcc cccttaatcg ttcaactgtt ccactttctg
     4981 ctaaaagttt aaaagctttt cgaatggtaa tcttacttac tccataaatt ttacataatt
     5041 cttcttctgt aggtaattgc tctcctggaa gatatttttt ttcacgaata tcgttacgta
     5101 tagaagcttc tacttgtaaa tataatggtc tattatcttg aaaattcata gtacactccc
     5161 taaaaagtta tacttcatta tatcacaatt tattaaaacg tcgattgtaa aattaagcta
     5221 gacaactaaa aagatcattt gtgctacact caaaatagtt ccgaccaaag aattaataag
     5281 gagtgagtac aaatgactta cacccatctt acaacagacg aactagtaat catagagtct
     5341 tatttcaata tcgagaaacc tgtcgctctt gtcgcacaaa gtttaaatcg ctctagacaa
     5401 accatttata atgtttattc gtttctcaaa caaggaaaaa aagtgctaga ttattaccgt
     5461 caatacaaac aaaataaatc tcgttgtgga cgacgttcaa ccgttttatc tgatgaacaa
     5521 tcaacatatg ttcaagaaaa ggtagctcaa ggatggtcac ccgatgtgat tatcggccgt
     5581 ggcgagtttc caattgattg ttctgttcgt acactctatc ggatgtttaa aaaaggcctt
     5641 tttgacacac agtcgttacc tatgaagggg aaacgtaaac cgaataatca tcaagaaaag
     5701 cgtggaaaac aggcctttcg cagaacgatt catgaacgga acagtctcta tccacacctg
     5761 actaaagaat ttggtcatct cgaagtcgac accattgtgg gagttaaaca caagagcgct
     5821 gttattacat tggttgagtg tttatccaag gttattatta ctttgaaacc gacaggcaga
     5881 cgagccgaag atatcgaaaa caggttaaat gattggttca aatccatgcc taaacacttg
     5941 tttaaatcca tgacatttga ttgtggaaaa gaattttcca actggcgatc tataagtaac
     6001 tcgaacgata ttgccatctt tttcgcagat ccaggaacac cttcgcaaag agggctaaat
     6061 gagcactcaa acggcttgct tagacgagat ggcttaccta aaacaatgga ctttagggac
     6121 acggatgaaa cctttattca atccgttgcc tcgaaaagaa accatattcc aagaaaatca
     6181 ttaaattatc gaacaccatt ggaagtattt ttgagctgca tagataaaga catattgtct
     6241 agcttaattt gacaaatcag atagtataaa atgaatcaaa ttgaatatca aatatatatt
     6301 atatccatga agcccaatct tctttaatag aagattgggc tatttttatg gcaaaggagg
     6361 gaaaagaaat gtttcaaaat aaaggacaac gttatgtcac aaagggagta atggacagtt
     6421 tgccggtgga attacaagct ttatgttgga atctaatcga tcaaaacgtt caaaagcaat
     6481 ttcatttaga ctatcttcaa atctttgaat tttctacgga aaaaggaaat caaaagttgg
     6541 ttcatcgtca agaagaacca gaagcaagaa aagagtatct gatttcacct aagcttcgtt
     6601 tgaaatcagt gtctcaaaaa atatgggtca ttgattcggg tgagtatcaa acgatgttat
     6661 taccagaaga atactgatat ctaaaagaaa ggaacgaaag gacttgttag aaacggctat
     6721 cgaagtactg gaaaagtgtg cacagctagt cactactcct gaagagtggg gctatgaatc
     6781 cgttacgatg gaaaaagagg aaattgaaat gggtatgctt cctgaagatg ttactctacc
     6841 acgtttagtg atgacacatc tttatattta ttgcgcacca gaagatggaa aagactatgt
     6901 agtttatttc attacagata ttaccagcca gcgagaattt gttcgtgggt tactggtaga
     6961 aggacgattg gtttggagtc agattggagg aacgaatgaa taagatcgat tatttgagaa
     7021 tgattgcgaa atgtttagaa gatatcctta cagcgattca tcaaattctg aagaaaaaag
     7081 gagaaagaat atgaaatatt ttcaactagt attgacactt ataacggcaa tggtgattga
     7141 attgcttgaa caaaaattag cataggagaa aaagagatga ttgaaaaaga attagtgacc
     7201 acacaaacag aagtttggcg agatcctcat catacccatc gctatgtttt caaacgacaa
     7261 tgggcgatca aaggaaaaga agcggaagat aaattagcgg tagtcattac tattcgtcca
     7321 acagatacag aaccatttac gaatgatttg agtatgttat taatcgaaaa gaatatccga
     7381 caattaggat ttactggttt tattgctgtg aatctttttt cgtatacaaa agcgaaaagt
     7441 cctcgggtat ttcctcgtgg aaatgatgaa caatctttgg aaatattaac aactgttttc
     7501 acagaaaaga aaatcaacac cattattttt gcttgtggtt cgattacagc gacgagtcaa
     7561 gtggcttatg aacaagcgaa gaccatttac gatcaattga gtgcgaaaca aaaaaagatg
     7621 accaaagtat tgataaatgc agaaggtaag ttatcccacc cactaagtat tcatgttcgt
     7681 aatgaatggc aattggcaga tagtcaatta ttatttcaag aaaaataaca ttttattttc
     7741 ttatgttact tataagtagt tttacatgct ttttgacttt aaaaatacat gtgatgatac
     7801 atgttatatg aattatcaat gtacccagta atatgctatt ttcattatgt aaaaaataac
     7861 agggggtgtg tagatggaga ttgatgaaac ttgtttgagt aactcttata aaagtatgaa
     7921 tgactttttt gaggaaatgg aactggattc agaattgctc tatcaatttt atcttgcttt
     7981 tcgagggcaa cagatttctt ttccaatgaa aatgtacgat cgtgagttag ttagaaaaag
     8041 aatcgaaaac atgatagaac aggaaaaaac tgtagatatc cgtcaattga cagaagttta
     8101 tggtttctct gcaagatgga ttcaaaaagt aattaaacaa aaagaaagga gacgagtaca
     8161 tggctaagct gattgtatta ggtggtttaa tttacggtgg atattggtta tataaatata
     8221 tgcttgcgca tccgaatata gataaaggaa aagtaattaa gacagttggg gtaatcatag
     8281 ttggactcat agctctaact aagaaaaata atactaatag cccaaaaata atgagaactt
     8341 atcgctgtag aggatgtgga agggaaattt ctactagttt taatccatct gaaagccctc
     8401 aaggaagaga tcgttgtcat gctggctatc gacattcttg ggaaaggatt aactaaatga
     8461 acaccattga gattaattga ctgataaaat aagtacgcga gggagaaatt gaaaggggga
     8521 aataaaatga aaaaatggtt gttattacta attggaatgg ggattttatt cactggttgt
     8581 acatctgaga atacgaggac taaagagact gtagaaactg atacaacaat tgaggctaaa
     8641 aaaagtaaaa cgcaatcaac tgaacaaact acaacagaaa tgaaacaatc tgtggaagca
     8701 agtacaagtg aaagttcaat cattgaatct tcttctgaag aggttaaaaa tactttgtgg
     8761 gatagtgaga aatctactca actagcaatt tttgtcccac aatggggaaa gacattaggt
     8821 caagaatata aaagctacaa tcctcagaac aatgtaagtc tgtatggtac gcctttacca
     8881 agtgcagtta ttgatggaaa ttggaaaatg gcaatcaatg aagcaccagt taccgtacaa
     8941 tggtcagaag atggaactgg tcatgcagat ttcaatttag tagcagttta ttctgatgta
     9001 gaaactggag aatatttagg gcagcatgta tatttctttg gctttcaaaa tggacaacct
     9061 aaagtttatt taacgcaaca aaatcaaggc aatgataaaa actacatgta cttcaatgaa
     9121 actcagaacc aacagttaaa acaaggtttc attgatattg tgaatggaca aactcctcaa
     9181 actccagtag tagaagaatc tactcaacaa gcaacaacta caacgacaca atctacaagt
     9241 agctcagcaa tttcaagttg ggaagctgct aaagaaactg tactaaataa taaagcttta
     9301 tggttgtatg attctcctga taaaaatgca tcaaatacta atttaattag cacaaatgaa
     9361 tatatgaaag atctaatgca agatgaaaat ggaagctact attcaattaa tattgtaacg
     9421 gatgataatg gaaatacaac aatggctggt ggaaaacaat tccgtgttta tacagatgga
     9481 agaatttctc aacgtattgg aatgactaac aattttcaaa tgattaaata attgaaaata
     9541 ttatttatca aagaaaaact gattttgaga aaaattattt aattttctta gaatcagttt
     9601 ttttataaag taaaaatgcg aaattaagta gatgagagtg atgatgttcg aaatatctat
     9661 tatttttaat aagaatacat aagctatcta gtttgtaaac aatgagagaa aaaacatc
//
LOCUS       DADVXE010000088         9420 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.091, whole genome shotgun sequence.
ACCESSION   DADVXE010000088 DADVXE010000000
VERSION     DADVXE010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.091"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            94..873
                     /locus_tag="KB913_002528"
     CDS             94..873
                     /locus_tag="KB913_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820830.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            919..1863
                     /locus_tag="KB913_002529"
     CDS             919..1863
                     /locus_tag="KB913_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6820831.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            1879..2658
                     /locus_tag="KB913_002530"
     CDS             1879..2658
                     /locus_tag="KB913_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBB6820832.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            2670..3368
                     /locus_tag="KB913_002531"
     CDS             2670..3368
                     /locus_tag="KB913_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBB6820833.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3396..4160
                     /locus_tag="KB913_002532"
     CDS             3396..4160
                     /locus_tag="KB913_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBB6820834.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMTASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPDYEEVKKKKFGLF"
     gene            4174..5991
                     /locus_tag="KB913_002533"
     CDS             4174..5991
                     /locus_tag="KB913_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6820835.1"
                     /translation="MFILTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVSIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            6045..6968
                     /locus_tag="KB913_002534"
     CDS             6045..6968
                     /locus_tag="KB913_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBB6820836.1"
                     /translation="MNAFKTALNNNEMEGKIIGADCSELAPALYMCDEKIVLPKVSES
                     NYIEELIKVIKFFEIKLIVPTIDTELSTLSRNKKYIENETDSVVLVSSEKVIDICENK
                     ILTSAFFEQNGFKTPEILNSSEITKFPVFIKPLNGSSSVNTFIVNNEKELLFFSEYID
                     NPLIQEYILGEEYTIDVCLNFDSTPVSIVPRKRIATRGGEILKGQIIKDRELIETTKK
                     MLEKLNAIGHITIQCIKNEKGIFYLEINARYGGGAPISIKSGANSPEYIIKMIDSKKN
                     LRYRENYLDKMIALRYDQAIYLDEKGNVYND"
     gene            6940..7656
                     /locus_tag="KB913_002535"
     CDS             6940..7656
                     /locus_tag="KB913_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBB6820837.1"
                     /translation="MKKEMYIMIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIF
                     PATFDEIYRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLEN
                     ADTLLTELRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPI
                     SYLLLLEKFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFY
                     QADKKIRSLWEIKNFLGVIS"
     gene            7653..8771
                     /locus_tag="KB913_002536"
     CDS             7653..8771
                     /locus_tag="KB913_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBB6820838.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            8761..9381
                     /locus_tag="KB913_002537"
     CDS             8761..9381
                     /locus_tag="KB913_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBB6820839.1"
                     /translation="MMRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLG
                     SPIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELP
                     ELWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKF
                     DLDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
BASE COUNT         3397 a         1521 c         1895 g         2607 t
ORIGIN      
        1 atttaattat gttttttaaa ataaaaagct gtcattttta tgtatgtgaa ttatatctta
       61 atttatctat catcaatact taggagtgaa tctatggaaa agccattcgt caagtcattg
      121 actgctgtgg cggtaggtgc aggtgctatt gcgatctgtt tgtttggtta ccatatcaat
      181 aatcagcggc aacatcagca acggatcaat tatgcagaat ctgccatcac caatcaaaaa
      241 gacaccttga cttctttatc aaaagaagta gacaagctgt atagtacaaa agaaaaaaat
      301 tttctaaacc ctgaaataac agaagaaaca atcacaagtt tgtcaaataa gctatcctct
      361 gtcaaacttt cagcagatga ttacgacatc aaagaatcag aattgcctaa agaagctgtt
      421 gcaatccaag atgagaagaa agcaatcgtg acacagttag atagtgcaga atcaaaactg
      481 aagatccaga cagctgtcaa cgatttattt actaaaaatg tatcaaactg gcagcaagct
      541 gtagacgatg tcgtcatcaa agaaaaggtg acaagtgcag atgtcgctcg tgtacgtgaa
      601 aatatgagct tttttaaaga tagtccttgg aaaacggttg ttatgcaata tctaggattc
      661 gctgatactc agatcgcgca agtcacgcaa ctagatcagt tattcgatac gatgttgaag
      721 gatggtcaag tgactgccac cgctacttac gatcaatatt tgacggcgct cagtcaaata
      781 gagcagatcc ggaatgaaaa aataagcgca gcatacgcaa caaaagcaca aactgttgct
      841 cagcaaatgg gctatagcaa tataagttat tgacagttaa aacgttgatt caagcaaggt
      901 tagcaaacgg aggaaactat ggcaagacga agaagaaaat caagagggaa aaaaatattt
      961 ctgattattt tagcagttct tatcgtatta gtattagcaa ttgtaggagt aggagcaaaa
     1021 ttatatctgg atctctcaca ttctattgag aaaacttacg aatcagtgga acgaacccaa
     1081 ggagaacgaa cgaaaccagt tgatctggac aaacaagaat ctttctctgt tctattgatg
     1141 ggcattgata ctggagattt aggtcgggtc gatcaaggaa gatcagatac gatgatggtt
     1201 gccacagtca gtcctgaaga caaacagaca acgatcgtca gcattcctcg agatacgtat
     1261 gtcgacatcg taggtcgtga cacaaaagac aagatcaacc acgcttacgc attcggcgga
     1321 gctgccatgg cgatggatac cctacaaaaa tatgtagaca tcccaatcga tcactatgtc
     1381 tctatcaata tgaaagggct aaaggaactc gttgatgcag ttggtggtat cgaagtcaat
     1441 aatgacctca ctttctcaca agatggctat gactttccaa tcggtaaaat tacattgaac
     1501 ggggatcagg cattatctta ttctcgtatg cgttatgaag atccaaatgg tgactatggt
     1561 agacaagagc gtcaaagaaa gatcgtagaa ggtgtagcaa aaaaagtatt gagtttaaac
     1621 ggtgtcagca actatcaatc cgttttgaat gctctagagt cgaatatgaa aacagacatg
     1681 agctttgatg aaatgaaaaa aatcgcttta gattatcggg aggcatttgg tacgatcaag
     1741 caagatcagc tgcaaggaga aggcttcatg caagataata tctcctatca aaaagtcagc
     1801 gatcaagaac ttgatcgtgt gaaaaaagaa ttaaaagatc aaatgaatct agagaataaa
     1861 taggaaagtg gagaaaaaat ggaagagaca atcagcttga aagaaatttt tgaaacatta
     1921 cgcaaacact tggtaacaat catcatctca atgtttgctg gcttggccat ctcaggaatc
     1981 gtaacatttt tcatcttgac accaaaatac agttcacaag cacaattgat cgtgacactg
     2041 ccacaatcag acacagcaaa tgtcaatgat gtcaatacga acctgcaaat gatcaatacg
     2101 tataaagata tgatcgtcag tgatttagta ctaaatgaag tcaaagatcg tttagaaaca
     2161 gaagacaatg tgaaaatgac tgctggacaa atcaaagatg cgatctccgt caatcagtca
     2221 caaaattcac aaatgttctc gatccaggca ataagcacga atgcagtgac tgctcaacag
     2281 atcgctaaca caacttcaca agttttccaa gagaacgcaa aagacgtgat gaatgtcgat
     2341 aaaatctcga ttatttcagg tgcagttgcc aatacgacac ctgtttcgcc aaataataaa
     2401 ttgaatctag tgattggctt agtattagga atgatggtag gcgtaggtct ggcattctta
     2461 ttcgaattac ttgatcggac agtgaaagat gaaaaatatg tgacggatgc attaggattc
     2521 ccaatcttag gaacagttcc agaaatgtca gcgaaagaat tgaacgctgg tatccgtaaa
     2581 aaaggaacag ctcctgcacg accaaaagct acaaacgata aaacagcccc atcacgcaga
     2641 agccgctcaa gagtctagga ggaagaaaaa tggcacgaac acagaaacaa aaagcagcac
     2701 aaactcatgc agtcagtttg atcacattaa caaacccatc ttcaccaatc gccgaacaat
     2761 atcgtacgat ccggacgaat atccagtttg cctccgcagc tggtcagcaa atcaaaacga
     2821 ttgtcgtgac ttcatcaggt cctggagaag gaaaatccac cactgcagca aacattgcag
     2881 tcgtttttgc taaatccggt caacgagttc tactagtcga tgcagattta cgtaaacccg
     2941 tcgtctataa gacattccag ctgaacaatg ccaggggatt aagtacagca cttagttcat
     3001 caggaagtgt agcagatgta atccaacgaa cgccagtcga gaacttgtcg attttgccta
     3061 gtggacctaa gccacccaac ccatcagaat tgttaagttc gccaagaatg gatcagatcc
     3121 tagacgaagc aagacagtta tttgacgtgg tgatattcga tatgccacca gtagtagccg
     3181 taacagatgc acagatcatg tcttcaaaaa cggatggcac tttattggtc gtacgtgaaa
     3241 atacatcacg taaagaatca ttgaataaag caaaagaact gctagagatg gtacaagcac
     3301 gagttttagg tgttgtatac aacggagcag aacatagcaa agatgctggt tattactacg
     3361 gaaattaagg aataagaaga gaggagacaa gagaaatgat cgatctacat tgccatatcc
     3421 taccaggaat cgatgacggg gcagaaaact tagaagcaag tattgcaatg gctgaaaaag
     3481 cgattcagca aggcatcacg catattttat gcacaccaca ccacaataat ggaaaataca
     3541 gcaatgaaaa atcacaagtc atttctctag tcgcttcgtt acaagccgaa ttagagaaaa
     3601 gacagttgcc tttgacgtta ttggaaggac aagaagtacg tattaccgga acgctcatcg
     3661 aagacatcca ccgagatgaa attttattta cagatttaga tgatacatat cttctgatcg
     3721 aatttccgac actggaagtg ccgttatatg cagaacggct tttttttgag ttgttagaac
     3781 taggaaagac accagtgatc gtccatccag aacgcaacgc gcattttcgc gaagacccga
     3841 atcatttgct tccgttccta gatatggggt gtttggccca acttactgcg ccaagttatg
     3901 ttggggtatt tggcaaagat attcagaaaa cagctaaaac aatggtcaaa cataatctcg
     3961 tgcagatgac tgcttctgat gcacacggag tctctaagcg caccttttac ttaaaagagt
     4021 gctatgagca gattgccaag gactttggta aggaaaaagt agtacagatg aagcaagttg
     4081 caaaggatct gatcaacggg gatgaaatca gttatccaga ctatgaagag gtaaaaaaga
     4141 agaagtttgg tttattttag ggggaattaa aaagtgttta tattaacaag aagaagaaaa
     4201 attgccacat tggtttttgt ggacagcttg ttattaattg ctgcaaatat tgcagcagct
     4261 aaattcatga agccgtttgt atctatacca atggatctta ttttaatctc tatcggtttg
     4321 tcgattggtt tttatttatt ttatggtagt ttattcaaag ttttcactcg gatcaatcgc
     4381 tatacaaatt taagagagat cattgcaatt tttagttcac tatctgcaag tgctgcctca
     4441 agtatcctca tactgctgtt cattaatcgg cgatacagtt tacggttagt tatctttgct
     4501 tatctgcttt cgctcttatt gatcatcggt agccgattga tctggcgtat ctacatcgaa
     4561 acaaaaaata tgagatacgt atcagcagat tctgctaaaa atacattgat tgttggtgct
     4621 ggcgaaggcg ggcgtatttt atacaacagc tttcttggat ccaaaacggc tcaagatatc
     4681 cacgttgtcg ggtttgtaga tgatgatcca aataaaagaa atacgtatct ttcaggaaaa
     4741 aaagtattag gtgcattaaa agatattccg gaattgattg aaaaatatga cattcaaatg
     4801 gtaacgatcg ctatcccttc cttatcaaga aaaaaattac gacgaatctt cgagttagtc
     4861 gaatccgctc gtgtgaaagt caacacgatg ccttctatag aagaacttgc ttcagggaaa
     4921 attagcgtat caaaattaaa aacaattgac gtagtggatt tactgggaag agatgaggta
     4981 aagctggata ttgaatccat caaagatcag atcacagaca aagtcattct tgtcaccggc
     5041 gcaggaggat cgatcggttc agaaatctgt cggcaaatca ttcaattcaa tcctgcaaag
     5101 ctattgcttt taggacatgg ggagaactcg atctacttga ttgaccgtga gttacgcacg
     5161 catcatcaaa attgtcctac agaaatcgta ccgatcatcg cagatatcca agatcgcgag
     5221 aaaatcaatg agatcatgga acaatatcat ccagatatcg tctaccatgc agctgctcat
     5281 aaacatgtac cactgatgga atataatcca aaagaagcag tcaaaaacaa tattttcggt
     5341 acaaaaaatg tagcagaagc agctaaagca gcaaaagtga aaaacttcgt catggtatcg
     5401 acagataaag ctaacaatcc tccaaatgtc atgggttcaa caaaacgaat cgctgaaatg
     5461 attgtgactg gattgaatga agaaggctgt acgaaattct cagctgtcag atttgggaat
     5521 gtccttggtt ctcgcggtag tgtgattcca gtattcagag aacaaattgc tcaaggtggt
     5581 ccaatcactg taacagactt tcgtatgact cgatacttta tgacgattcc tgaagctagt
     5641 cgtttagtta ttcaatctgg cgcattagca aaaggtggcg aaatttttat tctagatatg
     5701 agtgaaccag tgaagattgt agacctagcg aaaaacatga tccgattgag cgggtatagc
     5761 gaagacgaaa tcgaaatcat tgaaacaggt atccgtccag gggaaaaact atatgaagaa
     5821 ctattgttgg ataaggaaag aaatgatgaa gcagtttatg agaaaatctt tgtaggaaac
     5881 atcaaaggtt actcaataca aaaagtgatg gattttgtca agagcctgcc gcaagacgat
     5941 gaacaattgg ctaaagacat tgtcactttt gcaaatgctt cgaatagata ggagattaaa
     6001 aattgaatat tttaatatta agttgtggac gtcgttgtga actagtgaat gcatttaaaa
     6061 cagcattaaa caataatgaa atggaaggaa aaatcattgg agcagattgc tctgaactag
     6121 cacccgcact atatatgtgt gacgaaaaaa tagtattacc taaagtttca gaaagtaatt
     6181 atattgagga attaataaaa gtaataaagt tttttgaaat taaattaatt gttcctacta
     6241 ttgatactga attatcaaca ttatcaagaa ataaaaaata tattgaaaat gaaacagact
     6301 cagttgtatt agtttcttca gaaaaagtca tcgacatttg tgagaacaaa attttaactt
     6361 ctgctttttt tgaacaaaat ggttttaaaa ctcctgaaat tttaaactct tctgaaatta
     6421 caaaatttcc tgtatttata aaacctctga atggtagttc atctgttaac acatttattg
     6481 taaataatga aaaagaattg ttgtttttta gtgaatatat agataatcct cttattcaag
     6541 agtatatttt aggtgaagaa tatactatag atgtttgctt aaactttgat tcgacaccag
     6601 taagtattgt tcctagaaaa agaatagcaa ctagaggtgg ggaaatactg aagggtcaga
     6661 ttattaaaga tagagaacta attgagacta cgaaaaagat gttggaaaaa ttaaatgcaa
     6721 tcggacatat tactattcaa tgtataaaaa acgaaaaggg aatattttat ttagaaataa
     6781 atgcaagata cggtggagga gcccccatta gcattaaatc aggagctaat tcccctgaat
     6841 atattataaa gatgatagat tcaaaaaaaa atttgagata cagagaaaat tatttagata
     6901 aaatgatagc actgagatat gatcaagcga tttatttaga tgaaaaagga aatgtatata
     6961 atgattaaag cggtgatctt tgatttagat gacactcttg tgtctgaata tgattatgta
     7021 aaaagtggat acaaatgtgt agctagaaga ttagcagtgc aaaaaatttt cccggctact
     7081 tttgacgaaa tatatagagt ccttttagat ctttttgctg aagatagtaa aaatgtattt
     7141 aatcgtctat atgactattt tgaaattcct tatagtaaaa aagaaattaa agaactggta
     7201 aatgtatatc gagaacacaa accagacata aattttttag aaaatgcaga tactttatta
     7261 acggaattaa gaagtagagg atacaagctg gggattatta cagatgggta tgctataacc
     7321 caacgaaaca aattggatgc tttgaaagta gactatttgg tagattatat ttgtattact
     7381 gacgaattag gccgtgaatt gtggaaacca caccctatct catatctttt attgttagaa
     7441 aagtttaatt taaaggcaca agagtgtata tatattggcg ataatgagtt gaaagatttt
     7501 ataactgcca aatcaatagg aatgcaaaca attaaaatag aaagagtaaa tggtatttac
     7561 agagaaagca gtttgaagtt caaaagattt taccaagctg ataaaaaaat acgttcgtta
     7621 tgggagataa aaaatttttt gggagtgatt tcatgaaaag taaaagaatt ctattagctt
     7681 ctccacatat gagtgaagaa ggatatgaaa aagagtatgt aaaagaagca tttgatacaa
     7741 attgggttgc tcctttaggt gcgaatgtga atggatttga gaaagaatta gcagaatacg
     7801 tgggagctag tcatgctgcc gcattatctt ctggaacagc agctatacat ttagctttga
     7861 aagcggctgg ggtcggtaaa gatgacatag tgatttgtca gtccttgacg ttctcagcta
     7921 ctgctaatcc aattctctat caaggagcta tacctgtatt tgttgatagt gattacgaaa
     7981 cttggaatat gaaacctgaa catttgcgaa cagcactaga aaaatatcct aacacaaagg
     8041 ctgtattagt agtacatttg tacggtttat cagctaattt agacgaaatt actaaaatat
     8101 gcaaagaata cgatgttact ctaattgaag atgctgcaga atcattagga acaacatata
     8161 aaggaaaata tactggtaca tttggcgact atggaattta ttcttttaat ggaaataaga
     8221 taatcacaac ttcaggtggc ggaatgcttg tatccaatga caaagaaaag gtggaaaaag
     8281 tgagattttg ggctacgcaa tctcgtgaga aggcacgcca ttatcaacac aatgaaattg
     8341 gctataatta tcgaatgagc aatatcgttg ctggtatcgg tcgaggacaa ttgaaagtat
     8401 taaatgaaag aattgagaaa aaacgatata ttcatagttt ttataaaaaa gaattgtcta
     8461 aattgtcaaa tatacaattc atgccagaaa ataattggaa tgaaccgaat tattggttaa
     8521 gtgtcataac aataaaggga ataaatgcga atcatcttat tgatgagtta gacaaaaata
     8581 atatagaagc ccgcccagta tggaaaccta tgcatttaca acctgttttt aaaaattatg
     8641 attatattgg cgatgatgta gcagaaactt tatttgactt aggagtatgt ttaccatcag
     8701 atacaaagat gacagatgaa gatttaaaat atgtagtatc tacgattaaa agagtgatca
     8761 atgatgcgta aaaaaacttt ctatcagctt tttgggaaaa gaattttaga tatcctattg
     8821 tcaggaattg ctctcatcgt tttatcgccg ataatcttaa ttgtaggttt tttagtaaga
     8881 attaaacttg gttctccaat tatcttcaaa caagaacgac caggaaaaag tgaaaaaatt
     8941 ttttccatgt ataaatttcg tacaatgact gacgaaagag accacaatgg agaatattta
     9001 cctgatgaaa ttcgactaac taaatttggg aaaatgctta gagcaacaag tctggatgag
     9061 ctacccgaac tttggaatat tttgaaaggt gatatgtcga tcgtaggacc tcgtccatta
     9121 ttagtggagt atttgccact atatagtgag aagcaacgga aaagacacaa cgtaagacca
     9181 ggattaactg gactggctca ggtcaatgga agaaatgcta ttagttggga agaaaagttt
     9241 gatttagatg tttattatgt tgataaaatt agtttcttta atgatcttat tattataatt
     9301 cagacatgta aaaaagtaat caagaaagag aatattaata caatcaataa caatatccca
     9361 gaaaaattta aagggagtta aatacagcag cttaatgcaa gttttgtgac ttgcattata
//
LOCUS       DADVXE010000089         9313 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.092, whole genome shotgun sequence.
ACCESSION   DADVXE010000089 DADVXE010000000
VERSION     DADVXE010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.092"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            690..785
                     /locus_tag="KB913_002538"
     CDS             690..785
                     /locus_tag="KB913_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBB6820840.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(1087..1332)
                     /locus_tag="KB913_002539"
     CDS             complement(1087..1332)
                     /locus_tag="KB913_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820841.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1677..1961
                     /locus_tag="KB913_002540"
     CDS             1677..1961
                     /locus_tag="KB913_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820842.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            1964..2380
                     /locus_tag="KB913_002541"
     CDS             1964..2380
                     /locus_tag="KB913_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820843.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            2751..3431
                     /locus_tag="KB913_002542"
     CDS             2751..3431
                     /locus_tag="KB913_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HBB6820844.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSIASAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEI
                     KVLLGIPD"
     gene            complement(4046..5086)
                     /locus_tag="KB913_002543"
     CDS             complement(4046..5086)
                     /locus_tag="KB913_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBB6820845.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(5435..5761)
                     /locus_tag="KB913_002544"
     CDS             complement(5435..5761)
                     /locus_tag="KB913_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820846.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(5748..6551)
                     /locus_tag="KB913_002545"
     CDS             complement(5748..6551)
                     /locus_tag="KB913_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6820847.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(6904..7194)
                     /locus_tag="KB913_002546"
     CDS             complement(6904..7194)
                     /locus_tag="KB913_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBB6820848.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(7330..7509)
                     /locus_tag="KB913_002547"
     CDS             complement(7330..7509)
                     /locus_tag="KB913_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820849.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(7506..7856)
                     /locus_tag="KB913_002548"
     CDS             complement(7506..7856)
                     /locus_tag="KB913_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820850.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(7849..9174)
                     /locus_tag="KB913_002549"
     CDS             complement(7849..9174)
                     /locus_tag="KB913_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBB6820851.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
BASE COUNT         2905 a         1690 c         1437 g         3281 t
ORIGIN      
        1 cgttttttca tccattcctt tcttcccccc ttacaaataa ataataacct ttaacaacca
       61 actcgtaaat aggttggttg ttattataca aaaggatatt agtactcaga taaaaagttg
      121 ttagtactca gataaaaagt tgttagtact cagataaaaa gttgttagta ctcagataaa
      181 aagttgttag tactcagata aaaagttgtt agtacccttc tgtatccgtt gggagagtaa
      241 ggctcaactg ccccctaaaa agggttctaa aaaatcttta aaaaataaat aaaataaacg
      301 cgcgcgcgcg agcaaaattt cccgccaaaa aatcacccac tttttaaaat aaacaggttc
      361 gcgcatgata ttaaactgcc aatctagctc cctatggtcg ctgtaagaag gagtgatcgc
      421 tacgctctca cattttactt gcagcagtcg cctttaggct ccttcgccaa aaataattca
      481 ttagggactc ctttgtggcg tcctgagagc tcgtctaagc cgttctaaga caagattcga
      541 taaaaactat gtccttcgtt ctaaagcgcc ttacaggcgg tcagggcaag ccctaacaac
      601 cccaaggcaa taaaaaactt aggcttattt ttgctttttt attgtataat tgattgtcgc
      661 ctatccgaca gtcttgcgac tggaaggagg tgtgtttcgt gttcactaac tttatttgct
      721 cccttcttgt tgggctttta agcgctttgt tcagttactg gttgaataac cgaaacaaga
      781 agtaaaactt aattaaggcg actcagccca caaaaaaagc cccagagaat ccgacctctc
      841 tggggctttc gtgtgtttcg tgttcactta tttgcaatca aattataaca gaaataaata
      901 tttatttcaa aaatatccta caaaagtcta aaatccgtaa ttatttctta tatgcaacat
      961 ttacaaataa agtcgctctg agagctcgta tttttcgatt taagacgttt tatttagttt
     1021 ttggtgtatt tcattggtcc aagctaaaaa actcttagaa gcgattttag agccatttaa
     1081 acccacttaa ttatattctc catgaaattc gctccatgcg tcaaaagctg cgtctgaaat
     1141 tccgccgtct tcgttcacta gttgcattaa tttttccaac gatcgttttc tttcgggtgt
     1201 catattttta tattccaaca atttttcgtc tgttaaatcg aacttgattg cttgaattgc
     1261 ttgctctaat ttttctaagt tttgaaaata ttcgtaagga aatttttcca ttttttcttt
     1321 ctccagtctc acaatttttc tagaaataaa atcacttctt tgccgtctat actctcaaaa
     1381 aaaatgtcgt ttgaaaaact aaataaattt ttgatcgtgc atttttaaat ttggttatcg
     1441 attacacgtg cagcactccc ccccgaattt taaagagcat aaggaaacgt gtacccactt
     1501 tctaaaaaaa gtgggtagat aggctgtgcc tatcacgttt ctcagaaaaa aatttgatat
     1561 cactttttcg ccatcgtggg tagcttatgt atagcatttt ggcaaaaaac agctatacaa
     1621 atatagtatt tgtatggtat acataaatta tacataattg caaaaggaga ttttttatgg
     1681 acattttagt tcggaatatt gatccaaagt ttgttgcaac aatagacaaa cgttgccaag
     1741 aactcacgaa taaaacagga gaaaaatgga gtcgaaataa atatctaaaa gttttaatcg
     1801 aaagtgattt tgaccgtcaa cttacgactt acaaaaaaga ccaattcgat ttattgctcg
     1861 ataaatttat tgctatccaa acagaaaata ctcaaatatt aagcgagtat gtctacacaa
     1921 ataatcaaat cattgaaatg cttatcggag gaatgatata accatgagaa aaacttctgt
     1981 ccaaaaacat gttactttgt accctagtca tgttgacgtt ttagattcca tcatcgaaaa
     2041 aaatccagat atcaataact actcggaagc cattcgcttt ttatgtatga gttatgaacc
     2101 cgataccaac acgaccacta ccagcaatca ggcaaaacta aatgctatgg gaaaagaaat
     2161 ttccatcatg actgaaatca tcgcagaatt tgctgattta tatctaaaag atacaggcgt
     2221 tcttattggc acaaattcta aagtatatca agaagtgaaa gaaaaaatcg aagctaaact
     2281 aaatccatca aatcgaaatc gaccaaagaa tcatcaaaaa gaaaccagtc aaacagtcac
     2341 ttctagaaat ttcgacccaa caaattttct aaaacgataa aaaacagata ggagttattc
     2401 ctatctgttt tttatttaga agccccatac aatatgctag aatgtactag caatcttagt
     2461 cggttgtaag ggacttgtct acttgcttaa tgtaaggggg gcgagttctt ttttatttat
     2521 tcttctaacc agttacgcag agaaatcttt ggcaaatctg acgttaggct tgaaaaagta
     2581 aattctaatt tggcgatttt attgcccttt tttgctttta tttttgtgac tttaagatca
     2641 ttgaagtatt tttttagttc tcgtaatgca ggatttggtt ctgttgcaaa gttttaaatc
     2701 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
     2761 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
     2821 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
     2881 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
     2941 agaaaaataa aaaatccttt tattcctgga aaatggatga aacgtacatc aaaattaaag
     3001 gaaaatggca ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt
     3061 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
     3121 ttgatgaacc gaaggttgta gtcacagata aagcaccatc aattgctagt gcctttaaga
     3181 aactaaaaga atacggattt tatcaaggga cagaacatcg taccattaaa tacctgaata
     3241 atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac
     3301 gcactgcctc acccacgatt aaaggcatgg aagccatccg aggattatat aagaaaaccc
     3361 gaaaagaagg cactctcttc gggttttcgg tctgtactga aatcaaggta ttattgggaa
     3421 tcccagatta aatcatagat accgtaaggg attttattct ttatttaaaa ctttgcaaca
     3481 gaaccgtccg ttgcgggtaa taccgtaaca ctgaagggca cgcattaagg cgtcatctta
     3541 atgctttcct gtaggacact gacggagatt accagtctcc cgagccttac aggggccttt
     3601 ctttttttgt attttcaatt atcacaattt atcgtccaaa agtgcagaac gaaaatcaat
     3661 tcatcacaag catatcagac aattaaattt aaaacaacta aaaatataca aaaaagtgta
     3721 attgaatatt agcagcactg cctgaaaaga agtaatatca ggcttttcag cttggggaaa
     3781 taagtgaatt acctctcttc atgaattatt ataactcaaa aaagcacata tgcaaacact
     3841 agttccctat ttttttgaat gaaaaataac taaaatatct aacgattatg actttaaaac
     3901 ctacgtttgc gattgttttc ataaactttt aatctaaaaa ctccggaata atagctattt
     3961 atttgtaaca tttgtaataa aattaaaatc ataaaaaagt tctaatttaa aattgatcat
     4021 ttttatagtg atcgcttttt atcaactact ctagccaatt ttccgtacta actgttggta
     4081 attcgttaaa tgtttctctt tgttcgtttg caagctttgc cgcaatagct ttttcgacaa
     4141 accaattttt tacataaacg aaaattagat tctgcaaatt gtttactttt tcagtttttt
     4201 gtttttgata agctttcagc aaagtcatat ataatccttt gtcagcatca attccataag
     4261 attccagttc ttcataaaca acaactgttt gctctaattc ttcagctttt ttctttgcat
     4321 tatgaatagt ttggacggtt ttttgagcgt cttcgtaagt actagaaaat gtttttatca
     4381 agtttaatac attttctggt acaaatgtat ttatactgtc ctctttcatg atgtcgacga
     4441 agttatctag taaaacttga ttttgtaact gatcagtttc agtgtctatt atgtgtctat
     4501 tagtgtctat agaattagaa tagaatagat tgtctgcgat tttcgcaatt acggttgagt
     4561 ccttgatatg actggatttt gccgtatttg cgattttcgc aattacggtg gtatcattga
     4621 tttctcgcgg ttttgccgta tttgcgattt tcgcaattac ggtggtatca gtattgtctt
     4681 cctcttccat gattttaaag acgtcttgat tcgttacttc tggcttgcct aagtacaata
     4741 aattaggcat ggattcaatc ttaccgtcac gtttatttac tcttcctctc ttctgtttca
     4801 gaagacctgc tttttctaat tcctttttga ttttagatac tttaccttcg cggcattgta
     4861 acaatttcat taattcttca actgtgaata tgaaaaatat attatcatca gaatctaccc
     4921 agttattttt gactgaataa tcaaatcgat ctttaagtag catataagca atttttgcat
     4981 catttgatag atccatgtat ttttcgttag taaaaaatac cttaggcatt tgataatatt
     5041 tttcacgata aatttctttt gatttgtaat aattaaaatc attcatagcc aatcctcttt
     5101 ctgtaggata gcgttttgtt caaaactatg ttacaatgaa ttaaacaaat atatctatcc
     5161 actatatatt tttctactgc tgataagtcg ccaaactttg ttaaagcagt agtctttttt
     5221 tatctttttt tagtttacct taaaaaataa attaaagcaa accgctctat ttcaaggttt
     5281 aagctcatag taactatatc acgatattac aataatatta tatcacgata tcgtaatatt
     5341 acaatatgaa gataagcgac ttatcagctt tgatactact gatttttata aaaaaaatat
     5401 cacgatatta tgatatcgtg atattgaatg taaattaaat tttattttgt ttctttgcta
     5461 gtttatatcc ttcaatcaag tattcttcag gtatggactt taatagcgca tcttctataa
     5521 cgtctggttt acttttgtct gattcagcaa tagtcgtcca atatttgagt gctgacatta
     5581 gaattggatt tatacgaatg ctatctgctg ttcttacact acttccttga tcttttatga
     5641 ctttacttat atttttcttg gttaattcga tttcttctac ttcttttgat ttaaaattct
     5701 ttttattttt atttcctagt aatctactta ctgcagcttg actgcgatta tcttctgcca
     5761 tcaaaatcac caacttcttt taaatattct tctgtaaatg ctttatagtc atcttcagct
     5821 gttgagggtt tattaaaatt gattagatct gatccagcag cttgcgcttc gtcaacggtt
     5881 attgtcctac gaatataagt tttgaaaatt tttgcaccaa tgactctaga aatttcggtt
     5941 gctgcagacg tcatttcttt agaaatgtta taacgcttat tatacttagt aaatagaact
     6001 cctcgtactt caagcttgtc gttcgtatat tcttttaccg tttcaatagt ttcacttaac
     6061 tttattagtc cttttaatga gaaatacgca gcttcaactg gaatgataat ttcatcagaa
     6121 acagtaaatg cgttgactgt aagcattcct aaacttggtg gacaatcaat tataatataa
     6181 tcatagttgt ccttgattgg ttgaagtact cttttaagcc tgtgttcact tcctacttga
     6241 gtaaattccc tctctgcaga agaaagggct atgtcggctg gcaaaacatc aattccttta
     6301 tagtccagaa tagcatctgt aatgtcagcc tcccctttta atacttcata aattgtaggt
     6361 tggtttgttc catctatatc gaaacctaca ttatctgtag catttccctg aggatcaatg
     6421 tccactaaaa gtacattttt accgtaaaca aatttcaaac atgctgctaa attaacgcta
     6481 gtcgtagttt tagaaactcc acctttttga ttggctactg acaatattct tgccattaaa
     6541 atatccccca ttcatcttat attataatat aattatatca taatattgtg atattgcaat
     6601 atcgtatatg cattatattg taatattgtg tgattatttt gttttaaaga tatatatcgg
     6661 ttcggatata aagattattc atatgttatt cgaaattaaa ataatcactt tttattactt
     6721 taaaattttt tattaatgat aagaaatatg ttttgcgagc agcaactaga ataatttaaa
     6781 cattactaaa ctgtctatat tgttactaat aattcccttc ttatagtgca ttttcttaga
     6841 aaaaaacaat attacgatat catgatatta agatatcgta atattataca attgtgattg
     6901 atattatata tgttttttta tttttttatc atgtttaatc ttgaaggaat catattcttt
     6961 ttctaaagac aggagctttt cataaacatc agacatgttt aaactagagg ccaggcttaa
     7021 atcataaacg aatgaagcag gtaatgattt tattctacgt tgtcgggtta tccagcttgc
     7081 aaccgttcct tgtgggtagg catataactc acaaaattgt tctacagtga ttcctaaatt
     7141 cttgataatg taaacattga tcgggtgcga gtaaacaaat gtattgatag acatggtgcg
     7201 taagcctact ttcttttatt attgcgtttg caataatagt ttaacacacg cattattcta
     7261 gtatctactc ctatttgtaa aaacaaaaaa ggattcatag agataactct atagaatccg
     7321 taaaatacct tatatatata acgggaagat ataaaaccta aaattatgat aacctgctgc
     7381 agcttctaca tagaaagaga agcgctcaac accaacctca tttatcaaac gttggccata
     7441 accccaaatc tcttctgata gctgatcaaa ggttatatac tttagctcat attgctggat
     7501 aatgttcatt ctaatcgact ccatttatta tcctggtaaa attcgatatg acgtatttcg
     7561 tcgtagtgaa ttttgtcttt tccaacgtag atccccagct catcactacc taagatcttg
     7621 ccaatgatat cttctggata gtatccttca gcgtttcgtt cttctttttg aatagatact
     7681 gatctatttt ttatgactgc agcgttcaat acttccgcaa tctcttcagt cgtcatttgt
     7741 tcttttgcta aattttgact ggttcgttgt tcattgtcgg catcaatttc ttcagtatga
     7801 tcagataaat aaaaccctgc ccactttaaa cgtccacgat cattgtaatc aatcattttt
     7861 aattccccca tttccgcccg catgaccacc aacaagtgtg cttctagtaa tgcttctagc
     7921 gccttctaac attgaagaag catgtacaat cgacgtaaaa ccatattttt gccgaatctt
     7981 gtcaataatt ttatctaaat tttcttcgtc aatttgcttt tgtggatcac taaataaatc
     8041 cagctgaagc gaatcggtgt acacaagctt gctataggtt attccaacat gccttacttc
     8101 ttgtccttca taatacttat caaacaagaa aagacaataa ttctgcaatt cctttgtatt
     8161 atctgtgata gggatcttca tctggtgtga aaaccctggt ctcgtttcta agatcgacgt
     8221 gccaatgtgt aaatggacac aacctgtttt acagttatgc tgcctaatgc gtatcgctac
     8281 ttgttccgcc atttctttta ccaccagctc gatttcattt cttctagtat aatctcgtgg
     8341 taacacttgt gaatttccat atgatttttc ctttgtcggt tctggtggga ttgctatatc
     8401 tgttcgatcg atcccattag catggaagta cagctgtaag ccaatcacac ctagtctatt
     8461 cttaatcgta taaggattcc agttagcaag atctctaatg ctcataatcc ccatctgatt
     8521 gagtcttttt ttcattcgag agccaattcc ccaaaagtcc gtcatttcag gaatattcca
     8581 tactttttca ggaacgtttt cgtacgtcca ttccgcaaca aatccttcat tatgctttgc
     8641 ttcgttgtct aaggctagtt tagccaaaag gggattatct ccgacaccta ctgtagcaat
     8701 caatcctagc tcttctttaa tattctcctg gatcatttga gccagcttct ttctccgttg
     8761 acttcgtgtt ccttcagtcg taaaaagatt cagtgatcgg gtcactttta agattgattc
     8821 atcgatcgag taaatcagta gatcttcatc agccacatat cttctgaaaa tattatttac
     8881 ctgcatattt cgcttgatat ataggttcat acgtggtgga acaacgtgta gtgttttagg
     8941 aaatggttgt ggtaagtcac gtggtctact cacatttgta ataccatacc gcttttttgc
     9001 ttcaggagaa gaagctaata tcaatcctga accagtatta tcagctcgac tcataacaac
     9061 aagttctgtt gttaatggat ctaaatttct ttctatacat tcgacacttg cgtaaaagct
     9121 tttcatatcg attaaaaagt aatcatttac tggctctttt gaataatcca tcataaataa
     9181 cactccattc tttcacatta tacaaacata tgttcgatat tgtaaagaag aaatagctaa
     9241 atacataaaa aaagaagcat aggtatgcta tcaccctgct tcttcttttg atttgtatga
     9301 tcaatttatt cta
//
LOCUS       DADVXE010000090         9099 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.093, whole genome shotgun sequence.
ACCESSION   DADVXE010000090 DADVXE010000000
VERSION     DADVXE010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.093"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            203..427
                     /gene="nrdH"
                     /locus_tag="KB913_002550"
     CDS             203..427
                     /gene="nrdH"
                     /locus_tag="KB913_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBB6820852.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            586..2745
                     /gene="nrdE"
                     /locus_tag="KB913_002551"
     CDS             586..2745
                     /gene="nrdE"
                     /locus_tag="KB913_002551"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBB6820853.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            2795..3760
                     /gene="nrdF"
                     /locus_tag="KB913_002552"
     CDS             2795..3760
                     /gene="nrdF"
                     /locus_tag="KB913_002552"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBB6820854.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(3849..4988)
                     /locus_tag="KB913_002553"
     CDS             complement(3849..4988)
                     /locus_tag="KB913_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6820855.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(5297..6010)
                     /locus_tag="KB913_002554"
     CDS             complement(5297..6010)
                     /locus_tag="KB913_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBB6820856.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(6264..6965)
                     /gene="nagB"
                     /locus_tag="KB913_002555"
     CDS             complement(6264..6965)
                     /gene="nagB"
                     /locus_tag="KB913_002555"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBB6820857.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            7199..8731
                     /locus_tag="KB913_002556"
     CDS             7199..8731
                     /locus_tag="KB913_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6820858.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(8922..>9099)
                     /locus_tag="KB913_002557"
     CDS             complement(8922..>9099)
                     /locus_tag="KB913_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6820859.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         3030 a         1773 c         1591 g         2705 t
ORIGIN      
        1 atagttttcc acaatttttt ctctattaaa tttgctattt tcccacacga tacttgtttt
       61 cagctctttt ttcaaaaaca caaaacttag tattccacag tttccacaac acaatatgta
      121 gtgtttgttg tttgactttt ttactaagag ttttatacta tctattatag ataataagaa
      181 tgtgttagag gaggcactca ccatgaacgt aaaaatcttt tctaaaaata attgtatgca
      241 atgtaagatg gtcaaacggt ttttaacaga aaatcaaatt gcttttgaag aagtcaatat
      301 cgatgaacag cctgaagcag tagactggtt gaaagcacaa ggattccaaa gtgttcctgt
      361 cattacttct gatgcagaaa cagttatcgg attccgtcct gatcagttgc gtaaacttgc
      421 cagctaacat gactaaaaga atcaaaacgt gatacatgga tttgaagggc ttgagacagc
      481 accagttttt gtcgcaaact tccaaatcct tttttaaagc ttaaaaacaa tgcaatgatt
      541 tgcaatcaag catcatcaaa tacgaaatga aggttgggcg tacgtatgag tcttaaaaat
      601 ttacaagatg tcagttattt caagctgaat aatgaaatca atcggccagt caatggtcaa
      661 atccctttga ataaggataa agaagcttta gttgcctttt ttgaggaaaa tgtcaaacca
      721 aatacgatga cttttccatc tattatggaa aaaatcaatt acttgatcga tcaagaatat
      781 atagaagcag aattcattca attgtattca ccatcattta ttgaaaagct atatcaattt
      841 ttggacgagc aacatttttc tttcaaatct tttatggctg cttacaaatt ttattctcaa
      901 tatgcgttga aaaccaacga cggttccgct tatctggaaa cttatgaaga tcgagtagcc
      961 ttcaatgcgc tttactttgc gaacggggat gaagaattag cacttgctct tgcagacgaa
     1021 atgatccatc aacgatatca gccagctaca ccttctttct tgaatgctgg acgtaaacgt
     1081 cggggcgaat tggtgtcttg tttcttgact caagtcactg acgatatgaa ctctatcggg
     1141 cgctcaatca actctgcttt gcaattgtcc cgtattggtg gcggcgtagg gattacttta
     1201 tcaaatcttc gtgaagccgg cgctcctatc aaaggatatg agggtgctgc aagtggtgtc
     1261 gttccagtca tgaaattatt cgaagatagt ttcagctatt ctaatcaatt aggtcagcgt
     1321 caaggagctg gcgtggttta tttgaacgtt ttccatccag acattattgc tttcctttca
     1381 gcaaaaaaag aaaatgcaga tgaaaagatt cgcgtaaaaa ctctttctct tggcgtgatc
     1441 gtacctgata aattttatga attgacacgt aaaaacgaag atatgtattt atttagtcca
     1501 tatagtgtcg aaaaagaata tggtgtccca ttctcttatg taaatattac agctgagtat
     1561 gatcatctag ttgcaaatcc aaacattcgc aaacaaaaaa tcaaagcgcg tgatcttgaa
     1621 aatgaaatct caaaattaca acaagaatct ggctatcctt acgtaatcaa tattgataca
     1681 gcgaaccgcg agaatccaat cgatggcaag atcatcatga gtaatttatg ttcagagatt
     1741 ttacaagttc aaacgccttc tgtgattaac ggcaaacagg aatatgaagt attaggaaca
     1801 gatatctcat gtaacttagg ctcgacaaat atcgtgaatt tgatgcaaag ccctaacttt
     1861 ggtcaatctg tgcgtacgat gactcgtgca ttgacattta ttacagatgc atctgatatc
     1921 gatgtcgtac caccgatcca aaacggaaat aagctgaatc atacgattgg attaggtgcc
     1981 atgggcttac acacttatct tgcaaaagaa caaatggaat atggctcaga ggattcatta
     2041 gactttacaa atatttactt catgctgttg aattattgga cacttgttga aagcaacaat
     2101 atcgctcgtg aaagaaaaca agttttccat aattttgaaa aatcagctta tgctgacggc
     2161 acttatttcg aaaaatacgt aactggagaa ttccagccaa aatcagaaaa agtcaaagca
     2221 ttgtttgaag gcatttttat cccaactgct gaagattgga atgctttgaa acaagcagta
     2281 atgaaagatg gactgtatca tcaaaatcgc ttggcagtag caccaaatgg ctcaatttca
     2341 tatatcaacg atacgagtgc aagtattcat cctatcactc gcatgatcga agaacgccaa
     2401 gagaagaaaa tcggtaaaat ttattaccca gcgccttatc tatccaatga gacgattccg
     2461 tattacactt ctgcttatga tatggacatg cgtaaagtaa tcgatgttta tgcaacggca
     2521 caacaacacg tcgatcaagg catgagtttg actttattca tgcgttctga aatcccagaa
     2581 ggcatttatg aatggaagac aacaacgaag caaacgacac gtgatttgaa tattttaaga
     2641 cattacgctt tccacaaagg aatcaaatcc atttattacg tacgtacctt tactgatgat
     2701 gcagaagaaa tcggaagcaa tcaatgtgaa agctgcgtga tctaatatca tagatagatt
     2761 cgcttattca tattttaatt aaaggagcat tctcatgtca gaaacatatt atgaagcaat
     2821 aaactggaat gaaattgaag atatcattga taaatccact tgggagaagc tgacagagca
     2881 attttggcta gatacacgta tcccactttc aaatgaccta gatgattggc gtacattgtc
     2941 tcaattggaa aaagatacag taggacatgt atttggcggt ttgacactgc tagatactgt
     3001 ccaatctgaa agtggcatgg atcagttgcg taaagatgtc cgcactcccc atgaagaagc
     3061 cgttttgaac aatattcaat tcatggaatc cgttcatgcc aaaagttatt cttctatttt
     3121 tagtacactg aatacgaaaa aagaaatcga agaaattttt gactggacaa atacgaatcc
     3181 ttatctgcaa aaaaaagctg agcgtatcaa tgaaatctac aaacacggta caccgctaga
     3241 aaagaaaatt gccagcgtct ttttagaaac attcttgttc tattcaggtt tttatactcc
     3301 tctttattat ttaggaaaca acaaattggc taacgtagca gagatcatca aactaatcat
     3361 ccgagatgaa tctgtacatg gaacctacat cggttacaaa ttccaattag gattcaacga
     3421 gttacctgaa gcagaacaag aaacgttaaa agactggatg tacaatcttc tttatgagct
     3481 ttacgaaaac gaagaacgtt atacagaaga attatacgat ccaatcggct ggacagaaga
     3541 agtcaagaca ttcctacgct ataatgccaa caaagcattg atgaacctag ggatggatcc
     3601 actctttcca gatactgcca atgatgtcaa cccaatcgta atgaacggga tttcaacagg
     3661 cacaagcaac catgacttct tctcacaagt cggaaacggc tatttgttag gtcatgtaga
     3721 agcgatgaaa gacgacgatt atttgattgg attggaataa ggatttattt taattcaaaa
     3781 atttttcgaa aaataaaaag agtttagcgt acagatattt taaatgtaca ctgaactctt
     3841 ttttatgctt attcacttgt ttcttccagc acttttggac tgtctaactt ttccgaaaca
     3901 tgttccattc ttctcaataa atagattttc cggatattta atattatcgt cttaatcact
     3961 gcatagacag gtatgcaaat cagcatgcct aatattcctg cgacacttcc tgctccaatc
     4021 aataccaaga tgatcgtcaa aggatggata ttcattgatt tcccaaataa caacggcttg
     4081 atcaaatttc catctaattg ttggatcact aaaatcgaca acgccatata caaagcttga
     4141 aatggagaga taaacaaacc gacaatgatt gctggtaccg ctccaataaa agggccgaca
     4201 tacgggataa tattcgtgat tccgcaaatg accgcaagca acaagctata aggctgatcg
     4261 aatattctca ttgccaaaaa gctcattaca ccaataatca aagcatctaa gatcgtactg
     4321 ctgatatagg cagataatgt ttcgtttaat tcttttaccg tttggcgtaa ctctttacga
     4381 atcgctttcg gaaagaagtg agacaacgca tcaataaatt tgtgcccatc cttgaacata
     4441 aatagcaaaa taaatggaac ggtaaataac aaaataaaaa attgcatcat aaatgaaatg
     4501 atttttgaga cacttgcaga taaactgact aatatgatat tgaacaaatt actaagagat
     4561 aaatttgctg atgctaattg ttcttccaaa ttgaaatttt taaactcttc ccgctgcgcc
     4621 aattcattta accatttgct tgtttcatct gcatacattg gcaagctctg ggtcaattga
     4681 attgtctgtt ccattaactg aggcactaca ttcatgacag ttaaaacaac taaaatgatt
     4741 acgaccaaaa acgtcaataa aaaaccgaac actctcggga tccgatgctt ttcgagaaaa
     4801 acaacgattg gatcgaacat ataatagata aaaccagcaa caagcaatgg taaaaaaatt
     4861 gccgaaagca ttttcaatat tggactaaaa atattcggca tttgtaaaat aaagtacacg
     4921 ccgatgatcg tgagtactag ctccactgtc cagaaaaata attttgattg tttaaaacgt
     4981 gattgcatac atctcctcca aggtcctttg atacttctat tctatcattt aacaaagagt
     5041 tacgcgctga gattttcatt tgcttaaaaa aaacaaaaaa aataaacata ttttaatgag
     5101 tagacgagta cttaaacaaa aacacggttt ggagtagtga caaaaattat actgcagtcc
     5161 ctttttccaa ataaacggtg ttcaaaagct tgcatcttcg taataagccc agccaaacga
     5221 aaaatataag gaactatttt tatttggctg ggcttattac ttgatgtagg acatctattt
     5281 tacaacctca gatcatttat tgcgcaatac tgactaaatg caactttgtg atatttttgt
     5341 gtacggacaa ctcctcgatc acatcggcat aagtgagccc ttttggaaga tcaatcgtat
     5401 agatattttt gtacactcgg tagtcatcaa cgaattttac gtcaaaattc acatcttcga
     5461 ttacgatatt tttctcttca aaataatcgg taagaaaatc tttggtttct tttctatgga
     5521 taaattggat ttctaacttt ttagtcgtag gtacatggat cacgcgtttc actactgtga
     5581 gtgcaatagc aatcccgata aaactgatga tcgcaatgga atagtaaccc atgccgatgg
     5641 cgatccctaa tccagcaatt gcccataaag aagcggcagt cgtaagtccc gtcaccgatt
     5701 gtttcgtgac gatgatcgtt cccgcgccta agaaaccgac accactcacc acttgagcaa
     5761 tcagccttgc ttcatctgaa cgaatcgttc cagcaagctg tggatactct aaagcatctc
     5821 ttaatgcacc actagcgatc tcaacttgga tcaatgcaat gatacatgct cccatacaaa
     5881 ctaaaatatg cgtacgcata cctgctggac gatttttata ttgtcgttca aaaccgattg
     5941 ctccgccaaa tagcatagcg atccctaaac gtaaaataat ctctggaatt gtcaatacca
     6001 tatcattcat ctaaacaccc tccagtccaa tatatcatgt ctgaaaggag cagacaaaaa
     6061 aagtgcaatt tttacctctt acgaaaaaag gactgtgaca aaatttttgt catagtcctt
     6121 tttatgaata aacggtgttc aatcagctga ccctcggtat tactcaacaa acggcaaaat
     6181 atggggagct atttttcctt tgtcttctct aatactcagg tcaaaacgct gatttcacaa
     6241 cctctttagc ctactattga aaattacaac ttacttgctg cttcttcatc gatgatcaca
     6301 acaacattgt cgtgattttg caatacactt gctggcaaat gattcgttac aggtccttca
     6361 atcatccctt tgattgcatc agctttgctt tcgccaaatg ccatcaagac gatttcttta
     6421 cttttcataa ttgaaccgat tcccattgaa acagcttttg ttggtacatc ttctgcttta
     6481 tcgaagaatc gtttgtttgc attgattgtt gattctgtta agtcaactac tgaagtcgtt
     6541 ccgtcaaatg aagcaccagg ttcattgaaa ccgatatgtc cattttgccc gattcctaag
     6601 atttggatat cgattggatg tgcatcgatg atttgatcat actttttgca tgctgcttcc
     6661 agatcttctg cttttccatc tggtacaaac gtttctttga atggtttttt atcaaataat
     6721 tggacatcca tgaaatgacg gtagctttgt tcatctgaac cgcctagtcc aacgtactca
     6781 tctaagttta cagaagtcat ttcactgaaa tccaaatcgc ttgaagtcat ttctttatat
     6841 aaagtaactg gtgtgcttcc tgttgccaat cctaatactt ttgcaccttt gttcatacct
     6901 tctttgatga tttcaaatgc tttttttccg ccttcttcag cgttttttac acgaatgatt
     6961 tccatagtga ttgctccttt atattttggt atagcccaat tatagcattc tttttttctt
     7021 tttacaataa ttagtataga ccaaattgca tttttttcat tttcttgaca ataaatagga
     7081 atccgtgtta ggtttcataa gatggttcaa tcaaacaatc catgttgcat gaaaaccaag
     7141 caagtgattc actgtggacg ctttatgtct gcagtttttt tatgaaaaag gagttattat
     7201 gagtatactg acattaaaca acattaccca gcaatttggc gacaaaatcc tctatgaagg
     7261 tgtcgatctg caattaaatg ctggcgaaca tcttgggctg attggacaaa acggagccgg
     7321 taaaagtaca ttgattaaaa tcatcactgg tgagatctta ccagatgacg gacagatcca
     7381 ttggcaaaaa aatattcaca aaggttacct cgatcaatat gtggaagtcg atgaaacatt
     7441 aacaatcgaa gaatttctaa aaactgcgta cgcaaaagaa tacgaaaagg aagaaaaaat
     7501 tgcttttctt taccaaacat atagcgagac cttcgatgat tccttgctgg aaaaagctgg
     7561 gaaactccaa acggaattag accaaggagt gttttatcaa atcgacacct tagttgctga
     7621 gatgagcagc gggttgggga tcgatgtctt aggtttagat tcactgttga aaaatctaag
     7681 tggtggacaa cgttcaaagg tgattttagc aaaactactt ttagaaaacc cagatgttct
     7741 gatcttagat gaaccaacca atcacttaga tgatcagcat atccaatggc tgacgcagtt
     7801 tcttcaggat tttgacggtg cgtatatcgt gatttcccat gaccaagaat ttcttgatca
     7861 gatcaccacc catatcgcag acatcgagtt tggaaagatt actaagtata ctggccatct
     7921 aaaacaagca ttgaaacaaa aggaacaaaa tcgcgaaagc tatttgcgcc aatatcatgc
     7981 tcaacaaaaa caaatcgaaa agaccgaagc ttatattcga aaatacaaag ccggttcccg
     8041 atcaacgatg gcaaaaagcc gacaaaaaca attagataaa atcgaacggc tgacgcctcc
     8101 agcttcagca agtaaagctg tctttgattt tccattctcg cctattgtca cgacattagc
     8161 agtggaaaca actgatttag tcatcggata tgatcgaccg ctacttgcac ccatcaattt
     8221 gaccatccgc tttggtgaaa atattgccat tcgaggcttc aacgggattg gaaaatctac
     8281 tttattaaaa acactgatcg gtgagattga aaaaataagt ggcgatttcc acttcccaga
     8341 taacacaaaa atcaattact tttcacaaga tctgtactgg gaaaatccat tagaaacacc
     8401 actacaatat ttaagcagtc aatttccaaa agcgactatc aaagaattac gtcgccaact
     8461 agctaaagca gggttagtta atcaattagc aagtgaacct ctcactacat taagtggtgg
     8521 ggaacaaact aaggtgaaac ttgcacagtt gacaatgaac caaggtaatt tactgattct
     8581 cgatgaaccg acgaaccata tcgatcaaga aacgaaagaa agcttacaag acgggataca
     8641 gaaatttcca ggaacagtaa tcatcgtctc tcatgaacaa gaattttatc aagatcttgt
     8701 gcaacgagtc attgagattg aaccaaaata aacgtttgat tgaatagttg aaaaaaagga
     8761 gctgtgacaa aagttttgtc acaactcctt cttctgaata aatggtggcc aattagctga
     8821 ccttcggtat tagctcaaaa aacggcaaaa tatgaggagc tatttttatt tggctattct
     8881 tattacttga tgcagaacag cttttcacaa cctcttttcg tctatttttt attttcgaga
     8941 tttctctttc ctttaaaaac aactgtttga aagaagaacg cacatccttg aaaaacaagc
     9001 ccgctaaccg ttacacctaa ccagccatac tgctgccaca ttgtcgtccc tagcaatgaa
     9061 ccagccgcac ctccaataaa gtacataaac ataaataca
//
LOCUS       DADVXE010000091         9052 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.094, whole genome shotgun sequence.
ACCESSION   DADVXE010000091 DADVXE010000000
VERSION     DADVXE010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.094"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..135)
                     /locus_tag="KB913_002558"
     CDS             complement(<1..135)
                     /locus_tag="KB913_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain containing protein"
                     /protein_id="HBB6820860.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     L"
     gene            192..1319
                     /locus_tag="KB913_002559"
     CDS             192..1319
                     /locus_tag="KB913_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6820861.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1537..2679)
                     /locus_tag="KB913_002560"
     CDS             complement(1537..2679)
                     /locus_tag="KB913_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6820862.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2684..2869)
                     /locus_tag="KB913_002561"
     CDS             complement(2684..2869)
                     /locus_tag="KB913_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBB6820863.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(3223..3468)
                     /locus_tag="KB913_002562"
     CDS             complement(3223..3468)
                     /locus_tag="KB913_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820864.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3462..3863)
                     /locus_tag="KB913_002563"
     CDS             complement(3462..3863)
                     /locus_tag="KB913_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6820865.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(4050..5858)
                     /gene="uidA"
                     /locus_tag="KB913_002564"
     CDS             complement(4050..5858)
                     /gene="uidA"
                     /locus_tag="KB913_002564"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBB6820866.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5881..7647)
                     /locus_tag="KB913_002565"
     CDS             complement(5881..7647)
                     /locus_tag="KB913_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HBB6820867.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7660..8454)
                     /locus_tag="KB913_002566"
     CDS             complement(7660..8454)
                     /locus_tag="KB913_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6820868.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8464..>9052)
                     /locus_tag="KB913_002567"
     CDS             complement(8464..>9052)
                     /locus_tag="KB913_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6820869.1"
                     /translation="VFPDYYNDAQGIVLMNFINPILVLIVVSPLTLFLSKKYGKKELA
                     SVGMFFSAIVYLILFLIKASNMYVFLILSSVGYMGLGVFNTVIWANITDVIDDQEVKS
                     DQREDGTVYAVYSFARKIGQALAGGVGGWTLSIIGYDSLANVQTGDVLEKLYNASTLI
                     PSICFLIVGLILFFLYPLSKDKVLENCELLKQKHK"
BASE COUNT         2926 a         1728 c         1223 g         3175 t
ORIGIN      
        1 gagaaagtta tagacattgt aaattgtttg gcgtccacgt ttaagctgct tcgcaacgat
       61 agcaaccgga gtttcttgat gaaaatatgc ttctatcatt acaagctcgt ttggtgtaag
      121 atgggtataa gtcatttatg ttcactctcc ttgtatgctt tagcgggtat tacaattgga
      181 gtgtaacata aatggctttt ttatttgtct cgcttaatta tacaaacggc gaagatatca
      241 atgatgatgg ctcaagaaaa aaagtggaga aagttggcgg agacacccga ccagaggccg
      301 aagctgcttt acgaaaagtt ttatcagata ttgacgaaac aggacaatac tttttaggta
      361 cggatactcg agtaaaacaa taccttgatt tttggatgga ggaatacgtt aaactaaatc
      421 taaaatacaa tacctatgaa aactaccgat ttaccatcaa aaatcatata aacggttatt
      481 taggaaagaa aaaacttacg gatctctccc ctgctctttt acaaaatttc atcaatgctg
      541 aatttaaaaa gggttactcg aagaaaacaa tgactattac tcactctgtc cttaagaatg
      601 cgctgaatat ggcggtttat ccttggggat taatcaagca aaatcctatg ctgtatgtaa
      661 aaataccaaa atatgaagca cgaccaacga ctaaaaaaga tctaaaaatc atttctcttg
      721 aggactttga tcatatgcta gaaattactc ctgaaggaca tcctttctat attcctttga
      781 atattggatt ttatacggga atgcgcgttg gcgaagtttg tggtctgacg tgggatgatg
      841 tcgatttttc aaatggaaca attactgtag agaaacaaat ggtaaagaat gacggcgcat
      901 gggtatatgg tacgccaaag acaagcagtt ccaatcgaac gatttttatt ggacaaacct
      961 tgctagcaat tctgaaaaaa cataagaaac aacaattaga aaatcgaatg aagtatggaa
     1021 agctctacat tgattcaaat gcagtatgta cgaaggaaga cggtgagcta gttacgccaa
     1081 gtgtagtgaa atggaatact aggaggatat cgaatgcact ctccctctct tttaacttcc
     1141 attctctcag acatactcat gctacacttc ttctcgaaaa tggcgcaaaa atgaaagaaa
     1201 tctctgaacg attgggccac agcagaattt caattacgat ggatacttac tcgcatgtaa
     1261 cagataagat gagaaatgaa acggtcgata tcatggaaaa tcttagaaag aattcttgat
     1321 ttttgccacc gaaaaaaacc accggtggca aaccggtggc aaatccatgt aaacatggtt
     1381 tattttttac actgttttca aacaaaccct tgctatttct tcggttcgtc ctcgtccatt
     1441 ttcgataccg acagctagct tataacccaa ggtatatcaa cataaaaaaa taaaaatagg
     1501 ctatgacagc agcgtgacag caaaaaagat ggaaagttaa atatcaaacc tcgtaatttc
     1561 atttgcgagt gcttgatttg tttctggata taagtgtcca tatttgtcca aagtagtttt
     1621 aatagaggca tgacctagac gcttagatat tgcatagata tttttattat gttcaattaa
     1681 aaaggcaaca tgcgagtgtc ttaatccatg catatgaatt ggttttactc ctgcaatttc
     1741 agctagtttt tttattctgc ttaaaatagt tcttggagat ggcggtaatc catcaaaaga
     1801 aaaaaccaat tctatatttt tcccaattga ttgttgagtt tttttccatg tttttaaatc
     1861 ttcaacggtt tgtctgtcta acgaaattat ccgaatactt gatgtatttt ttgtttcagc
     1921 aaattcataa tcttgtcttg tacggatgta aattgactta tttacgctac atctgccatt
     1981 tattaagtca aagtctttcc attgtaacgc taagagctcc tcactcctta cacctgtaac
     2041 aaaaataaaa cgcatcaaac gtttataaaa ttcttcataa aaatccccgt gataaacact
     2101 attatatact ttcttaaatt catcaactgt ccaaaattct acttgaggac gctgagtttt
     2161 tattttacct atagtatcta caggattttc ttcaataatt tcaagtacaa ttgccctttt
     2221 aaaaactact ctcaacttat tgaatatctg tttaatataa tttggtgata atggttgctc
     2281 aatgcccttt tttacaacat ggattttcga taaaaactgt tgaaattcct gtatatgaat
     2341 tggtcgaatc tttacaacct gcatttctcc aaaaaaatcc aatgcacgtt gtaaaatatg
     2401 atctgttttc atatatgttt tttctacagt tcccaactta taccaaggaa aaaaatactc
     2461 tcgataaaaa tcatgaaacg ttattccttg cagataaatt ccttgtgaat cagaaaaact
     2521 ttgttttaac tcttcgagtc cccttctagc ttctccttga gttttgaagc ctcttctggt
     2581 cacttgaatt ctttttccaa agcgatcttg tcctaaagtt gcagaaaaaa accaagtgcc
     2641 tctttttctg tctttataaa cattcgcaat tttcctcatt ttactattcc tcccaagaaa
     2701 tatggagaac ttcttctaaa attgaaatag gaattctttt tatttttgaa ttacgataaa
     2761 aaaagtatcc tttctcaact aaaagttctt tacattcctt gaagatttta ttagcatagt
     2821 actgagaaaa acctagatta atcaaatctt ttcgagtagc tgttttcatt atagcacctt
     2881 ccttactttt tttcatttat ttctatcagc tgcttttgtc aaaagcacat aggaatttca
     2941 cctctcccca agtttacggc gagccttacg gaagtatcat tatcccaact ttaaatcatc
     3001 gctttttatt gactataaaa attattttag aatatttatc gctccttctt tacagcaaga
     3061 aatcatggcg caactaaaat atgctcctta aagtgttaac gtactgatag aatctattta
     3121 attttcaatg aacaataggt tttctaccta aaagaatcta ctaattcctt aactattaga
     3181 agattctttt aaacagaaaa agtggaaagg ggattttttt aattagttaa ttttaaattt
     3241 taagatcgct tctattaatt taatttctag ctgacttatc atatattcat ctacataggt
     3301 aacgaattga cctacctcgt taaatccatt tgtcaaacat aacttagcca tataagaatg
     3361 ataatgtttg agtatcatct tgatcgaaat tggatctcct tctagagcag ataagataat
     3421 ggatagtgga actaataggt actgccgctt tttagattta tctaccatag gtcatacccc
     3481 attttcaatt gttcaactgc cttctttcgt tgataccaga taccacttgt gctcatattg
     3541 agaattttac cgatttcagc atcattaaaa cctgcaaaat aataaagtag gataatcttt
     3601 cttcttatct ccgataactg atcaattgct gctgataact tttgatctga aattaatatt
     3661 tccattccaa ataagaaata gacatcttgt tcatcaaaat gagtttggga atacctgcct
     3721 tcatttgaat ctgccaatgg ttcctcatta tcctttatgt tagcgtttcg ttttcgaata
     3781 gacttagctt cgtttcgtaa tactttttta cagtaggcat caaattggtg ttgtatagat
     3841 atgtcattgt aatgttgttg catgataata tgctcctttt tccccctttc cactaataca
     3901 acaatcagaa agcccctttt tttcgaaaaa actagaaaaa aaacataaaa atatttatca
     3961 ttctttaaac agaaaatctt tctataaaaa acaaaaaaaa acgattaggc taggctaatc
     4021 gttttttgaa cattcttaaa aaatccaaat tattttttat aactgaaatt gggtattgat
     4081 gaccatcgtt tctgtagata gtaagcaatc attttaggtt ttctatctct agtaaagatt
     4141 cctttcttat ttccttgcac tcttaaaatc ccttgacttg ttgcaaaatc tgcaaaattc
     4201 cacacttgtt caccaacaaa attttcacat gtatctatta cttcgtgatt tgcttcgtaa
     4261 taagccactt gatactcttc tgtaaacatt gttggtactg tatcatgaaa tccagctact
     4321 gtatctgctc catattctgt aaacattatt ggcgtatcag gacatctttc catccatcca
     4381 tctagctctt ttttcaacag atattttgca tgtgccagat cccctcccga aacataccaa
     4441 ccataataac gatttaaaca taaaacatcg acaatatctc ctaccttaca aacatctggc
     4501 gttgatttta gataagtaac gattgttaca ggtcttttct gcggatcaag ttctttagtt
     4561 aattcaacta aaggttcaaa atattcttta gcaccttcgg aatccgaatc tggttcattt
     4621 gcaatagacc acattacaac acttgggtgg ttcttgtcgc gttctatcaa ttccttgatc
     4681 accgttttat gagaattttc tgttcgtatc tctttccacg tattatgttt ttccacatta
     4741 tcatctaata aagtggccat gaaatttaaa tgtaacccta ctgcaggtac ttcatcaata
     4801 actacaatac cttctcgatc tgctaatcgc ataatttctt ctgagtaagg ataatgtgat
     4861 gttctaaaag aattagcacc tatccatttc attaaattaa aatctttaat atttacagcc
     4921 tcattcaaac cacgtccatt aacatacgaa tcctcatgct taccaaatcc tttaaaataa
     4981 aaaggtttat tattaatcaa aaatttgcca ttggtaacct gaacactgcg aataccaaat
     5041 tcttctgtat aggtatcgat cactttatta tcatcaatta aactaatttt catactatat
     5101 aaataagcgt ctagaggttc ccaaaaaatt ggattcttaa gctgaatcat tcctttcttt
     5161 ccttcagctt cagctacaag ttgagcctct tcgtcatata tcgctattaa gatttttccg
     5221 gtccattctg tatcgatatt gaattctaca cttgcatcca aatcagttat tcttgtatta
     5281 atagtaatat cacttatata gtctttcgga gttgtatata acttaacagg tctatgaata
     5341 cctgcataat tgaagaaatc aaaattaact aagttttcct tttttatatc cccattttcc
     5401 tgtactgttt ccttcataat ccccacaggt aaagtactat cgtcaataat attgtttaca
     5461 gcaactgtaa ttcgattatt cccgtctttt acaaaccgat taatttcaga ctcaaatggt
     5521 gtaaacccac ctttgtgttg agtaataaac tttccattca aaaaaacttt tgcttcatgt
     5581 gttgcagatc caaaacgaag aactaatctt tcttctaata atcttttagg aagagtcact
     5641 tctttttcat accacaccca tccaacatga tttctaatgt tctctgtttc aaataaatca
     5701 ttataagaag agggaactga aatcggataa ctctcttttt catttattgg ttctaaagca
     5761 agttcttcct gtaagtcatc atttgtatct aatttaaatc tccagagacc gcttaagtca
     5821 attacttgcc tcgtctctgt cataatggga tacaacatat aaaccactcc tatctaaata
     5881 ttaaataaat gtatccttta aaccacaata agcatctatt ggacttactc ccttaaattc
     5941 agaaagaccc attagtttgt ccaccaatat ttctaaagtt tcttgttttc catcataagt
     6001 attaatataa gtctttactt gaggtacatc agccaaatga aacggacact gtacagatac
     6061 aaaaattgtt ggaatttcat gaatgtaaaa cggtatatcc ggagttcctt tacttgctgg
     6121 ccagacaatt cgttgaactg tgcctggatt aacattagct atattaatga tcaagtcata
     6181 ttttttagtt aaatttttaa ttggtctctt agcagcatat attccagcta tatttttaat
     6241 tttttcttct tgcgataatc ctttcaattc ttcttcaggt gaaatgtatt tttcaacttc
     6301 aaatcctttt gctgacaaaa tctgtttcaa taaatcaatg gcttgaggtc tatttccagc
     6361 aactacttca ccaaacccac cttttacccc atgtacatct actagtaaaa tccttttata
     6421 tttttctggt acaataggcc aaatatcttg tttatcttta actaatgtaa ttgcttggtc
     6481 agccacctct ttaaaaattg atttattttc aattaaacca attttttcca gagcttcttg
     6541 cttaggtaat aaaatttgtt cttttgcttt tttgtgtaat cccaatttag cttttaaccc
     6601 taaaattctt tttaaggcat ctaataaccg atcatcagtg ataattcctt tacgatagcc
     6661 ttccatcata taattaaagt cttcatctgg atcattaaaa aatagaaata gatcacatcc
     6721 agctgcaata gaagtgggca ataattctga tcgtttcatt gccccagtca ttcctaacat
     6781 atgactagca tcagtaacta ctaatccatt aaatccgagt tttcctctaa gtaagtcagt
     6841 gattaattct tttgataaag ttgcaggaag taaatcttca tctttcagat caggattaaa
     6901 atgttttgaa taagctggca tatggatatg acctgccata attgaaggta atccagcttc
     6961 tattaagcct gagtatactt ttccaaaaga attatcccat tcttccgtac ctaaactatt
     7021 aatactaaaa gatagatgct gatctcgttc gtcaataccg tcaccaggga aatgtttagc
     7081 tgcaggcaaa attccactct cctgaatacc tttcatataa gctaaactaa gttctaaaac
     7141 tttatcaggg ttttgtccaa aagatcgact agaaatgata ggatttctcc aatttctatt
     7201 aatatctaca ataggagcaa aactccagtt acatccaata gccgatgctt caatcccaga
     7261 aactctccct aattcataag catatttcgc atcatttgtt gcaccaattt ttacttctac
     7321 accaacttca gtaccatctg tacaagctcc gttaccacct gcttccgtat tagcagcaat
     7381 taatagagga attttacttt ctgtttgtaa gatatagttt tgatcatata cctcatcagc
     7441 agttcctgga ttatatcgta cagctccaat atggtactga ttgaccatat tactcaagta
     7501 atttttatca cgactagatc ccatattaac aaacaattga cctatttttt cttccaaagt
     7561 catagaatca atcgtctctt caatccaaga aatagcatct tcatctaaat tatatggttt
     7621 ttttcgtaaa tctactttta tagtcatttt ctttctcctc tacttattag taagattttt
     7681 ccaaaaagta tctatatatt tttgttcaat atctacataa tctcccgata aacatttaaa
     7741 taaaacatca gttcttaagt tttcccatga ttctttttct ttattgacca aaataggata
     7801 aaagaaaact ttatttttat ttgcagcttc tagatcacca ggagaatcac caatcattaa
     7861 tatcttatcc aaatcacaac cattttcaat tacacttcga ataatatctt ctttttttcc
     7921 tttatcttga caacacagtt catcaactaa tgataataat tcatgtcttt cccattcttc
     7981 ttgaacagct tccttattag ctgagcttac aataattatc ttcccatatt ttttcagagc
     8041 ttttatagta tctctagcac ttaaaaaggg tttatctaat ccttttgctt gactaatctg
     8101 ttgattgact tcttccgacc attttaaagc ttttaataaa tcctctgact gagaatattc
     8161 tatttccctc ttcaaagatg gattagacaa ttcttttgtt agagataccc agtgctttaa
     8221 tcgattaatc gatgttacat catttttttc taatgtttta actaaaccta aaaatctgtt
     8281 tattccacga gtctctgaat ataaattaat attattccaa tcctgtagga atttttctct
     8341 atgatgaaca tcaaaaatct ctgcagcaat tggtccgaaa aagagattgt gtttataagt
     8401 catcgtatcc ataacacagc catctgaatc aatacaaaat atccaattat tcatatttct
     8461 ctcctattta tgtttttgtt ttaaaagctc gcaattttct aagactttat ctttagataa
     8521 tggataaagg aaaaataaaa ttaatcctac aatcagaaaa caaattgatg gaattaatgt
     8581 tgaagcgtta tataactttt ctaaaacatc tcccgtttgt acatttgcta aagagtcata
     8641 gcctataata gaaagagtcc aacctccgac gcctccagct agagcttgac ctatttttct
     8701 agcaaaagaa tataccgcat atacggtccc atcttctctt tgatcagact ttacttcttg
     8761 atcatcaata acatcagtaa tatttgccca aataacagta ttaaacacac ccaaacccat
     8821 atagccaacc gaactaagaa ttaagaatac atacatatta ctagctttta tcaaaaataa
     8881 gatcaaatat actattgctg aaaagaacat tcctactgat gccagttctt tttttccata
     8941 ttttttactt aaaaacaaag ttaaaggcga aacaactatt aaaaccaaaa taggattgat
     9001 aaaattcatt aaaactattc cctgtgcatc attatagtaa tcaggaaata ca
//
LOCUS       DADVXE010000092         8937 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.095, whole genome shotgun sequence.
ACCESSION   DADVXE010000092 DADVXE010000000
VERSION     DADVXE010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.095"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(1062..1475)
                     /locus_tag="KB913_002568"
     CDS             complement(1062..1475)
                     /locus_tag="KB913_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBB6820870.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1931..2416)
                     /locus_tag="KB913_002569"
     CDS             complement(1931..2416)
                     /locus_tag="KB913_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820871.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2555..2770)
                     /locus_tag="KB913_002570"
     CDS             complement(2555..2770)
                     /locus_tag="KB913_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBB6820872.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2994..3794
                     /locus_tag="KB913_002571"
     CDS             2994..3794
                     /locus_tag="KB913_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6820873.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3813..5681
                     /locus_tag="KB913_002572"
     CDS             3813..5681
                     /locus_tag="KB913_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBB6820874.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5674..6165
                     /locus_tag="KB913_002573"
     CDS             5674..6165
                     /locus_tag="KB913_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBB6820875.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6153..6707
                     /gene="srlA"
                     /locus_tag="KB913_002574"
     CDS             6153..6707
                     /gene="srlA"
                     /locus_tag="KB913_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBB6820876.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6725..7720
                     /locus_tag="KB913_002575"
     CDS             6725..7720
                     /locus_tag="KB913_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBB6820877.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
     gene            complement(7862..>8937)
                     /locus_tag="KB913_002576"
     CDS             complement(7862..>8937)
                     /locus_tag="KB913_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBB6820878.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT         3076 a         1444 c         1700 g         2717 t
ORIGIN      
        1 aaatcattca tagggaagtc ctcttttctg tgaattggtt gtcgttaact ttattctaca
       61 gaagggactt ccttttttgt atggattttt tcatttacac aaaatatttt atactctctt
      121 ttgttactat gaataacata ataagaaagt aaagtggatt gatttgagat ctttttatac
      181 ttcaaaaaag ataacaccca actttcaaaa atatgttttg gaagttggga caaacgagtt
      241 aatacatttt aatacattat tttttattca aaaaaaatag cacaatggca aagatcgtaa
      301 gagagatcat aagccccaat gaatgactaa aaagaaaagc agaatcacat gccatatcat
      361 cccatatttc ttcaagaaaa taaataagcg ggaaaaaggg aaggaatagt agaacatcga
      421 tccagcacca tttttttctt cttttgaaat aacataaaac aataaacatg aacgtgcagg
      481 gaagtaaaaa caaagcttta ctcataacta acaaaatacc agctcctttt atttttttct
      541 cccccacatt caaagagtaa caatggtatg tacttaataa tagaaaaatg gatcaacttg
      601 tatgaataac agctgaaaag atctgcacca aataaaaaac ttccagccaa aactgactgg
      661 aagtttattt ttttctgaaa tattctaaca caaatatgaa aaagatggcc gaagctaata
      721 agccgatttc gtagcaaaac aatgagatac cagagtcgta ataataaaat cctctaatct
      781 tatggataaa atagatcatc ggacaagcag ataagagtaa gtatttgtta ggccttttga
      841 ataagtaaaa gaaagcactg gtcattatga taaatggtat ccaaaacaaa agtttactta
      901 agacaatcaa atgatcaact cccatatttt ttaccaagag agatcataac atctttatcg
      961 taaaaacaaa atattttttt gctcattttg aaaatttaaa catactcgtt cttatccaaa
     1021 tatataaaaa tcgcccctca ttcatcgaga ggcgataagt tctaatttaa ctcaattttt
     1081 tttgtttctt ttggctgata agctgtttta ggtaatacca atttcagcac accgttttta
     1141 aaggttccag tgattttttc ttcatcaaca ttaggaagat agaatgaacg tttgtaagag
     1201 accgaatgtc tttctttccg tacatagttg ccatcttctt tatcttctgt atgggactca
     1261 tgattggcgg agatcgtcaa agtattatct gaatattcaa ctgtcgtgtc ttctttgtca
     1321 cagccaggca tatcagcagt tagtttgtat tctttttcat tttcgactaa atctactttt
     1381 ggataacttg aaacacctaa aaaatcattg aatgctggac taaacacgtc attgaaatca
     1441 gggaacatgt cgcgaatgct aggtacattt gccatttttg atcatccttt caataagtat
     1501 tttttattta tccctattta cgtaataact ctattttgaa aaaaatgcaa gtataatggt
     1561 tagctttgtg aatatttcat ctaatacgat acaaaggcta tctttctaat ttgaaaaagg
     1621 gatcattaaa ataataagaa gaaaatatgt caaaaggtaa aaaagtaaat tcttctatcc
     1681 aaatatagaa aaattgaatc tagaaaaccg cccgacaata aatttcatta actcagttga
     1741 ccgaaaatga agtagatacc aaaaatttat caagagagca agtagagaag tgagtatatt
     1801 cataagagaa atagctgtaa cgaattatta ggttaatgca aatgcttatt tatactccgt
     1861 ataactttct cagaaaaaat gataccaata atgacttgct agtactgtaa atccgtataa
     1921 tatcatctaa tcaaaatggt gttccatttg catctgtcat cgtaatcgat ccttcgggtg
     1981 acactcgata aaaaccaacg cttccagatc ctccttggga acggatttgt ttgctggaag
     2041 ctgtgaacaa ataatctcga tcaatttttt gataaaagct aataacaata tcgtcacttt
     2101 gtaattcgga acggtgggca ataagaaata gaagtgcttt gtcagagttt tctaatggaa
     2161 gagaaggtac agtgctttct tgcatttcag atgttgaaga aatgctaaac gactgaatac
     2221 ttgattggct atgttgcgaa tctacattac cagtagaagt attagtaatg gaagtagtag
     2281 aagtactttt agttgaacca acctcagttg ttgaaatggc tgctgaagat tctttaacag
     2341 aattctttgt tttatatcca caggcagaaa aaagtattac agttcccaac aagcctgcgt
     2401 aaatcccttt atgcatgata gctcctccta aaatagatta tctttattca gtatatcact
     2461 taaacaaaga aaagcagatg gtttaaaatg aaaaaacctt cccaataaag ggaaggttca
     2521 tgaagataat aactttttta ataattatag ctttctaata tctttcatca acttttctag
     2581 taatcattgg gaaaaatttc aagcagtaga tcgcacaaat acctacgacg atataaatga
     2641 tcttcgcaaa aatagttgtt gaaccaccag caatcatagc tactaaatca agttcgaaca
     2701 agcctaccaa cagccagttc aaccctccca caatcaataa agttaatgca atagcatcta
     2761 aagttttcat tagaattctc ctttcttaaa tgataaaaca attatatatc aaaaagagaa
     2821 acattgctta tataacgctc aggaatttta gcaatctatg caaaaagatg aaaatttttt
     2881 ttgctcttcc attagtacac attttttagc tgaagctgta aatttcatgt cttaattttt
     2941 tttagtgagc ttttatactg gatttgtaag aaaaaagaag gagaggatca catatgtcgg
     3001 attggttgga tattgcagga aaagtagtaa ttgtaactgg aggttcctca ggaattggaa
     3061 gaagtatcgt cgaaaatttg ttgaagcaga atgcacaagt agcgaatttt gatgtaactg
     3121 aatgccgtat acagcatgaa aacctactat ctttaaaagt cgatgtgtct tctaaaacgg
     3181 acatagaaga agggatatat aaagtaatga aacatttcaa gacgatcgat ggtctagtca
     3241 ataatgcagg aataaatatt ccttctcttc taatagatag aaatcatcca aaaagcaagt
     3301 atgaattatc agaacaagtt tttgataaga tgatcgctgt caatcaaaaa agtgtatatt
     3361 tgatgagcca agcagttgga agaatcttgg tgcaaaaggg atcaggagtg atcgtgaatc
     3421 tttcttctga atcaggattg gaaggatcag aaggacagag ctgttatgct gctacaaaag
     3481 cagcgatgaa cagttttact cgttcttggg caaaagagtt aggaaagagg aatgttcgtg
     3541 tggtaggtgt tgcaccaggg atactggaag aaaccggttt gagaacacaa gaatatgaag
     3601 aagctctttc ttatacgaga ggtataagcg tcgaacagct gagaaacggt tacagtcgaa
     3661 caagtacgat ccctctagga aggagtggta agctgcaaga agtggcggat ctagtctgct
     3721 attatctttc agaaagatca agttatatca ctggagtcac gactaatatt tcaggaggta
     3781 aaacaagagg ataaaggata ggggggacgc acgtgacgct agtaaacaga tggtaccaat
     3841 tattgaaatt actagtcact cacaagaaag tttcaatcca ggaagtgcaa aaagaaatca
     3901 aaaccagtaa tcaaaccata aaaaaagata ttggggagtt gaatgaagaa attgccggta
     3961 ttgcaaaaat catccaaaaa aacaaacatt ttgaacttga aatttatgat tttgattttt
     4021 ttgatgagat catgcaagga aaattgaaaa cagccagtga tttcaattcg gcatccaaaa
     4081 gaatcgctta tttactaaat aggctgatcg aaacagagga tttcttacgt atggatgatt
     4141 tgtctgaaga agtcggtgtc agcagaggaa cagtggtcaa ggatctaaag acattaaaag
     4201 agatgatcaa tgattttgat gtaaagatta caggcacacc aaataaagga ctaagaataa
     4261 taggagatga gctagaatta cgactacttt tattttattt tgtttctccc tacttttcag
     4321 agacgaaaac agaacagttt ctagaagaaa aacaagcaat caaacatttt cagaagaaga
     4381 cgaatgctag taaacaagaa atcacccttt taacgaaagt tatcggtatt tctttgaata
     4441 gaatctctag taactatctg ttgaagaagc ccatcaatcg ttacagtggg tgttttgaat
     4501 atatccaaga attcaatgaa ctgatcaatc agttggaaga aatctatgaa ctaactttga
     4561 gccaatatga aaaagatttt atcagttttc ctttgaacat catcaacaca agtataacga
     4621 tgataaggaa agctaactct gatttgcgct tatatttcga ccccatgatg atgcgtattc
     4681 gacgattaga tctcattgat ctggatgagt ccttcttata tcaagagatg aaacagcacc
     4741 tctctttatt gataaatcgg gtaatttttc gttatcgatt gactgattta ttttatggtg
     4801 agatagaaaa aaagtatcct ttttcttacc aaatcgctag cgaatgcata caagcattag
     4861 aagctatctt gcaacataag atctctaaag tagagatcag ctacctaacg ttgtatttgg
     4921 agttagcatt tcgatatcaa aaagagcatt tttcctctaa aaaagtagcc attgttcata
     4981 cgacaggaaa aggaacagca ttaatgatcc aaagacaaat caaaaggata ttggggaggg
     5041 atatacaaat aacacatgtt tcagaagaac aatatgaaaa agtagatcta aacaaatatt
     5101 tcgctgtttt tacaacgatt ccgttaaaaa atgtaaatga agagacaccg gtgatccatt
     5161 tgactaatct ttttgatgac tcttggttaa gggcacaatg gcaaaaagca aaaaaaaagc
     5221 gattagccgg gtttcattct actgtttttt tctatcaaat atggaaagaa aaaaagacgt
     5281 atcaagaata tttaaacaaa ttagtcgctc ctttgatcag aggctattat gtggatgaag
     5341 aatttgaaaa aaggatcttg aaaagagaat atcagcaaag cacatttgtt aacaaagaat
     5401 ttgcttttcc tcacacaacc aaccagctat ctcaacacat tgttttatca gtagggctaa
     5461 taactgatca aggtttagca gaaacaggag gaaatggagt tattttttta tttgccatac
     5521 ctgaagaaat gacggctgaa gttgagaatg aattatttga gctatacgat atcctatttg
     5581 aactcataaa aatgggaata gatgagttta ttgaattagc accgacacaa gaatcatttt
     5641 taaaactaat caaaagtaaa ggagagagac ttcatgaatg atatgtatct attcatagtt
     5701 ttcgcagctt cagcttatgt gctgcaagca gttatcagtt ggaagcaact aaagcatttc
     5761 aatcaaacat atagcgaact gcgaagaaaa ggaaaagtag cgattggtaa acgacctggg
     5821 aaaatccgtt caggcacgat tgttatgcta gctatagacg atcatgatca agttttagaa
     5881 gtcagaaaaa tgcaaggggt tacatctttg gcaaaatttc attcattacc tgtctatgcg
     5941 ggtgaagata tccattacat cgatcgttac catccctcag ttcgagcgga agatcgtttg
     6001 acacaagcag ctttagaaaa tgccagagaa gtatacttac gaatagaggc aggaaatgaa
     6061 aaaagtgaac aaccttcatt gccttttatt gctatgctca ataattttcg gatatggaaa
     6121 agtacgatca aagaaaaaag gagtgacaaa cgatggatat cataacaaaa tttgctgagg
     6181 gatttatgag gctgttccaa acaggtgcag aaacattcat aagctggatg acaggaatcg
     6241 taccagttgt cttgatgctg atggttgcaa tgaatacgct gattgctttt ttaggtgaag
     6301 accgagtaac gaaagtagcc aaattatcag cgaaaaatcc gcttactcgt taccttgtgt
     6361 taccgttctt atctgctttt atgttgggaa atcctatgtc atttacaatg gctcgtttcc
     6421 ttccagaata ctacaaacca agctattatg ctgctcaagc tcaattttgt catacgagca
     6481 atggtgtatt cccccatatt aatcctggag aattgtttgt atggatgggg attgctcaag
     6541 ggatcgaaac cttagggcta aattcgatgg agctggctat ccgatacttg cttgtgggac
     6601 tgctgatgaa ctttattggt ggttggataa ctgattttac tactggattt gtatgcagac
     6661 agcaaggaat cgttcttagc aaaaaagtag agctttcagt tgattagaga aaggagagtt
     6721 ttaaatgtat ggtgatatta agatcgtaag aggaaacggc gggtatggag gtcctttgat
     6781 tattaggccg acaaaagata aacacaagtt catctatgtc acaggtggag gtgagaggcc
     6841 aatgatcgta gataaaatag aagaactgac aggtatggag tctatcaatg ggttcaaaac
     6901 atcaatacct gatagtgaaa tcgcgcttgc aatcgttgac tgtggaggga ctcttagatg
     6961 tggaatttat cctaaaaaag ggataccaac catcaatatc gtttccacag gaaaaagtgg
     7021 cccattagca caatatatca ctgaagatat ttatgtttca gcagtagggt tagaacaaat
     7081 acagccacta atggaaactg atgataacaa agaaacagta aatactgcat ctccagataa
     7141 aaagtacaaa tatgatactt ctaaaaagat aaccgagcaa aaagcagagc agcaaaactg
     7201 gatagcaaaa attggaatgg gcgcgggaaa agtagttgct acattcaatc aatcagcaag
     7261 agaagcagta gatacgatga tccggacagt gatccctttt atggctttcg tttccctttt
     7321 gattggtgtg atacaaggtt ctgggatcgg taatgtattt gctaacatta tggcaccttt
     7381 agcaggaaat gcagttggat taacaatcat tggctttatt tgttcactgc catttttatc
     7441 tcctttgctt ggtccagggg cagttattag ccaagtgatt ggaacattga tcggtgtaga
     7501 gattgggaaa ggaaatattc ctccccaatt agcattaccg gcactatttg ctatcaatac
     7561 tcaaaatgca tgtgatttta ttccagtcgg tctaggtttg gaagaagcaa aagctgagac
     7621 agtagaagta ggtgtaccat cagttcttta ttcaagattt cttaacggca tcccacgagt
     7681 tatcattgct tgggtagcaa gttttggatt atatagctga gtttagtcta atggtgataa
     7741 gtcaagatga aatttaagat tttctttatt gagtaatatg ttttgaagcg cacgaaacta
     7801 gacccgatca aaatcaaatt tttttcgggt tgattcaagg atttgcgtca ataacggatt
     7861 gttatttctc tatcacactc cttggtggcg tatagagttg gtgtttacgt agtagcgtat
     7921 ccaccagacg cgtaaatttt cttgcggtta ggacgagtgc acgtttgtgt tgatgctttg
     7981 gaacctcctt atatttactt tgataaaaag ctttgtattc aggaagataa ttttttacag
     8041 agttggcagc ttcaactaag tagtatctaa aatatcgatt tccttgtttt gtcagaggtg
     8101 tattttgcga ctgatagttt ccagattggt tcactttcca acttaatcca gcgtattttg
     8161 ccaattttgt ctgatcttca aatctttcga tttgaccaat ttcagcgatt aaaccggcag
     8221 catagacttt accaacgcct ggaatactgg ttaagcattg atattctgga atgacaacaa
     8281 ttacttgttc gatggcttta tctaattctt tgatattttt ttcaagtgct cgtatttctc
     8341 gtacgagaac acttaaaaca acattaattg attcttgtgc aagagcacct aggcggtaac
     8401 tcatggtaat tgcacgttga attgctttag cgattttttc tggttgcttg aaacggcctt
     8461 ttcctttttc ttgaagtaaa tcacagaaag cttctaaagg aagctcagca agttcatcca
     8521 atgtgaaatc ttccgtcatg agtgaaatga gggttgcact aaaaagactc gtcgattcgt
     8581 ctcgcatttc tcgagcaagc gtattacatt tgtacgttag attttcaaga aaatgttgct
     8641 ttgtacgaat caattgctta ataagttgat agcgagtacg tgttaaacgc tgtaaggcca
     8701 tgtatttctc ttctttgata ggggaagttg tgaatcgttg aatacgcaag aaatcagcga
     8761 ttcttaatgc atcgtttcga tcagttttat tctcatcaaa catgcgacta aattgtttca
     8821 cccgaaaagg attttcaatc gttacaagtg tgttgagctt ctttagtttc tcatcttcat
     8881 gaaaaaacat ggaaggatgg aagctgtaca tggacgttga ctccatgcca atcacaa
//
LOCUS       DADVXE010000093         8850 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.096, whole genome shotgun sequence.
ACCESSION   DADVXE010000093 DADVXE010000000
VERSION     DADVXE010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.096"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            63..1277
                     /locus_tag="KB913_002577"
                     /pseudo
     CDS             63..1277
                     /locus_tag="KB913_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1456..1785)
                     /locus_tag="KB913_002578"
     CDS             complement(1456..1785)
                     /locus_tag="KB913_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6820879.1"
                     /translation="MNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSKYH
                     TKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQRL
                     EERMEEL"
     gene            complement(1775..2047)
                     /locus_tag="KB913_002579"
     CDS             complement(1775..2047)
                     /locus_tag="KB913_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBB6820880.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2498..3301)
                     /locus_tag="KB913_002580"
     CDS             complement(2498..3301)
                     /locus_tag="KB913_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6820881.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3279..4403)
                     /locus_tag="KB913_002581"
     CDS             complement(3279..4403)
                     /locus_tag="KB913_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820882.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4419..5234)
                     /locus_tag="KB913_002582"
     CDS             complement(4419..5234)
                     /locus_tag="KB913_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6820883.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5224..6096)
                     /locus_tag="KB913_002583"
     CDS             complement(5224..6096)
                     /locus_tag="KB913_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6820884.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(6181..7470)
                     /locus_tag="KB913_002584"
     CDS             complement(6181..7470)
                     /locus_tag="KB913_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6820885.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7698..8342)
                     /locus_tag="KB913_002585"
                     /pseudo
     CDS             complement(7698..8342)
                     /locus_tag="KB913_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2742 a         1883 c         1409 g         2816 t
ORIGIN      
        1 caaaatcaat tctaccttag atgttcttat atcactctat cagtcctatt tgacaaagag
       61 ccaagaaaaa gacgttggtc gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa
      121 gttgtggttc tactgtggta gatggaaacg ggaaagcaat tatagtgaaa aatgggaaga
      181 aggaaacgat tgtccgtttt gaacaataca atcatatgcc tttggttacg cgcctaaaaa
      241 agcaacgcta tacctgtaaa aactgtcgta cccattggac ggctcaaagt tattttgtcc
      301 gactcagcca ttcaatcgca gatcatgttc gatataaaat tgcttcttta ctgactgaaa
      361 aagtatcttt gtcttttatt gcgaaaagtt gtcaggtatc tttgactacc gttactcgta
      421 cattgaaaga gtttaaaagc tatttaccaa agccttctaa gaagattctc cccagagtat
      481 tgatggttga tgaatttcgt tcgcacgctt ccatagaaga taaaatgagc tttatttgcg
      541 cagatggtga aacaggaaac ttaattgctg tcttgcctac gcgtaaatta cctcgattaa
      601 caagctattt cttaggctgc accaatccag aagaagtaga attcttagtc acagacatga
      661 acgccgctta cttccagctt accaaacgtg ttctgccaaa tgcgaaagta gtgattgatc
      721 ggtttcatat tgtcaaacac atgaatcagg cactcaatga gttgcgtatc cgtgaaatga
      781 atgagcttcg taaagcagga cagaaaagtc aggcagaaaa actgaaaaag aactggcgct
      841 ttctgctaaa aaatcgtgca agcatcaacc attatgagta caaaacatgg aaaagtttcc
      901 gagcaccaaa atacccattt ctcactgaag caatgatgat tgatcgattg cttgagtttt
      961 ctgcgcctct aaaggaggcg tatccctttt ttcatgaatt agtcgaagcc tttcgagaca
     1021 aagaccctga cttatttttc tccttattgg cagaacttcc cgaaacgtta gatgacggct
     1081 ttcgggagaa gcttcaaaac cttctgacct atgaagaagg tatcaccagc gcaatgatct
     1141 atccttattc caatggaaaa attgaagcga agaataccca cataaagaca atgaaacgag
     1201 tatcctacgg atttaaatca ttcgagaaca tgagaattag aatctttttg atcaatcaat
     1261 taatcaatgt aagataacaa aaaatctgaa ccagaatgtg gttcattctg acccggattt
     1321 gattttgcac aactcatcag tccttattga caaagagcca aaaatctgag ccagaatgag
     1381 gttcattctg acccagattt gattttgtac aacccatcag tccttattga caaagagccc
     1441 ttctttttag tattattata attcttccat gcgttcttcc agtcgctgta aatcgcttgg
     1501 acttaattcc ccaatttttt tccatttgac ctttttgttg tttttgggta attcgtttag
     1561 agttcctacg tcaatccaag attctttttt tagtcctgcc tgtttccaat cccttatttc
     1621 aacgtatttc agctttattt tatcggattt agtatgatat tttgaagtaa ttgacagaaa
     1681 cgaaattgtg tccagtccat tttttagaat atagacaggc cggcgtttac cgccctctgc
     1741 agctgtgaaa gcaacgtaga cggttgctat atcattagta ttcatcttca ttgaaccatt
     1801 cttcaatttt ttcgtcagtg tctagttttt ggacaggcaa tttttccgct aatctttgaa
     1861 tattatggat tcgtttactt ttttccgaca attcaataga aaatgggatt tttccttgct
     1921 caacaatttg cttataaaaa acggtgacgg ctgttttggg gctcatgcct agttcatcaa
     1981 taatgctttc tgcttcattt ttcaattttt cgtccataga aatttgtaac ttagccattt
     2041 tctccacctc tttctgacaa acacattata tcacggaaag agttcaaatg gaattaatac
     2101 aactactttt gaactccttg aaatgcagtg tatttatcta aatataagga aaggatatag
     2161 tgctaaatgg ccttgataga tagaaaagtt tcaaaatccg ccacagcgat aattgaagcg
     2221 aacactcaac gacacacaga acaggaaaag actcctaaaa gaaccaaatt aactaggacg
     2281 tgtctgaaaa ctccacaaag atgtggtatg ctctggtaaa aaacgaatgg cacaaccacg
     2341 aagaccgata tggttcttgg aaaactttct ccaccctttt tgtaattgga gggatagtgg
     2401 tttattgata gcgattttcc aagttcttca agtggaacca gacattgagc accacggcta
     2461 aaaagtgaat gaagtcttta tttttaatca ataattttta atgattacca gtaattggtt
     2521 ttttcatgcg ccctatttct atttgatgtg gagttaaata atgctgataa gtaaaaattt
     2581 ttccgtcaat taaactgcca ctagtgaatc ctgttctatt ggtaaaaaga gaatagtctg
     2641 ggtattcatc tacaccaaat gataaagatt cagccataaa ctgtttttta ccagcaaatt
     2701 cagcactgct accttgatgg atatgtccta caaaaatacc taaaatatca ctttcggcaa
     2761 tcaattcagc aaaaccttcc ggaacttcag ttacaataga tggatcttcc cacgacaatg
     2821 gatgatgaac caataaaatc gttccctttt cagcaggtgt acccaaccac tcttgtaatt
     2881 gaatcatctg tcctatcgat atttttcctt cgtgctgggt atcttgagca gaatccaagg
     2941 aaataattcg taacccattt tgattcgtac aatggatata ctctcccgtt tcattgcttt
     3001 caacactcat tccttcaaag aaaacactgc gacgatcatg attcccacga caaaaatagt
     3061 aaggtgtggt tgggaaatat tgatccaaca ttttccgtaa gacttgataa tcagaaatcc
     3121 ccccttcatg tactaaatca cctgttaata gaataaaatc gtacactgtt aacgagagtt
     3181 cttgtaacaa tttttccaat gccaactgtg gatttttaat tgttggaaat agttcagcag
     3241 taaacaagtt agtttgatag ttttctctaa aatggatatc agagagatgc aaaaagcgca
     3301 tggctattcc ctctttcttc aataaaataa tcaggatatc ctaaattttc ttgcgtctga
     3361 taatcaaaaa aatgcattct ttcaggttct atgcggagat tgactgcatc accaatctgc
     3421 caagtaggtt tttcattaag gacaatcatt tctataccat cgactttaac ggtgtacgca
     3481 taactttgac ctaatagctc acgatacttc acttgaccgt gtaaatcgct tgtttctttt
     3541 gaaaaggtta cgtgttctgg tcttatgcct aaatacaatg agccactaac ctgaagaagt
     3601 tgtttttgcc aagctggatt caatgttaaa aattgactgg ctacctttaa tgttccttga
     3661 tcataagtaa ctggcataat attcatgcct ggcgaaccaa taaaatttgc agtaaaagta
     3721 tttttaggtt tcgtataaac atttttcggc gtatcaatca tctgaattct accttcattc
     3781 aataaaacaa tccggtcagc taacgtcatc gcttcaattt gatcatgagt gacgtagaca
     3841 aaagtttgtt tataacgttg atgaattttt accaattctt ttcgtgcatc caatcgtaaa
     3901 cgcacatcca aatttgataa cggttcatct aataaaaaat aattactccg tttaaccacc
     3961 gcacgagcca atgctacacg ctgccgttgc cctcctgaca aatctttagg aagtcgatct
     4021 tggtatggcg ttaaacctaa catcttcaaa gcttcttcca aacggtgctg aatgtcagct
     4081 gtcttaattt tattcgccct taatgcaaaa ataatattct cctttacagt catgtgagga
     4141 tataaagcat aattttgaaa aaccattgcg atctctcgtt ctccacaagg tagcttattt
     4201 gctagttgtg tacctaaaaa aagctctcca ctcgtaattt tttccaaacc agcaatcatt
     4261 ctcagcaaag tagattttcc tgaaccagat ggtcccagta acacaattcg ttctccagcg
     4321 gccacagcta aatcaatttc ttttaaaatg gtatgttctc catatttttt tccgatattt
     4381 cttaattcaa gcgtttctcc catgatttgt cctccaattt atttaatacc tgcagaaaca
     4441 aaagtcccga taatatattt ttgaaaaatt gcatacaaga ctaacggtac aaacattgta
     4501 attaaactaa tcgccattgc tacggtaaaa tttgtcccac cttcagaact aatataggtc
     4561 tgcatcgcca acggcaaagt ataattatct actgtccgta aaattaatac cggccaaaca
     4621 tactcattcc aagaggtaat aaaaaaccaa ataccggtag aagtaatcgc atgtctagta
     4681 agaggaaaaa caattttact catgacggtt gtttgtttga tgttatccaa tgccgccaca
     4741 tctagaaggc tcactggaat ttcccgcatt gtttgcgtca ataaaaaaat gcccatcgca
     4801 tcagcaaatt gtggtattat cacaccccaa gtagtatcaa ttaaattaag ttttgcaatc
     4861 aacaaataat taggaatcat cgcaacagta aaaggaatga acatcgtacc aatgatgata
     4921 aagtaccaga ttttcttccc tttgattcgg caataagtaa aactatatgc cgcaaaaaaa
     4981 gctacgccta acttaacaac cgttataatt gtagcaataa aaaaagtatt tctcgtaatt
     5041 ttgataattg gaagattttc gaacaaatag caaaaatttt ccaaggtaaa cggctgtggt
     5101 atcaaactag taatcgtctg ataggcatct ttcaatggct taaaagaatt ggccataata
     5161 aacaataatg gatagataat aatgattatg atgaacataa ataagagatg tggcaaccag
     5221 cgtttaattt tcatagtaaa cccccttttc cacaaattta aatattaccc ctaagaaaac
     5281 agcaaatatt aataaagtta aaactgaaat tgctgaagat tctccgactt tatacatttc
     5341 aaaagccttt tgataagcat aatagatcac gtttgcacta ccattattcg gtccaccacg
     5401 agtgatgatc ttaatcggag taaacacata ctgcagacct tgaacaatgg tcatcaccaa
     5461 taaatatagt cctgtcgaac tactcatagg caacacaatt gtaaaaaaaa tgcgccagat
     5521 gggtacacga tccaacttag ctgcttcgat catctcttga tcaattccca caattgctgc
     5581 aaaaatgaca atgaaattat aaccaaaaac tttccaagca gtaatacctg caatcacagc
     5641 aattacccaa ccttgtaaat tcatccacat aggcagtctt aaaccaaaat ttcccaacaa
     5701 gacagcaatt ggtcccgata ccggatttaa tatccatgta aaaaccatcc ccgccactac
     5761 caaagaaatc acagctggaa taaaaaataa tggtttatac aaattctgcc ctttttctat
     5821 aactattcct aataaaaagg atgtaatata tgggaacaca cagctcagca agacaaatag
     5881 aacggtatag gacaaagtat tcttcaacac tttatgaaag actggatcag tcagcacctt
     5941 tacatagttg gcaaagccaa caaattcttt agtgggggcc accatattcc agtcaaaaaa
     6001 actcaaatag atcgtataaa tcaatggata aaaaacaaac acgcccaaca aaataattgc
     6061 tggcgccaga tacaaataac ctacatagcg cttcatttcc gacagcctcc tcatccttat
     6121 gtcaaaagca gacgaccttg tttttccttt cttacaggcg ctgtcgtctg cttgctttgc
     6181 ttatttgagt aactcattaa tttccttttg agtagctttc atcgtttcat tgacggaatt
     6241 acctgataaa attttatccc gcatatccaa caatttttgt tcagcttcta atccagcatc
     6301 tccaggaaat gaactccaac tgaccatctt atccatctga tcaattgctg gtatcatcat
     6361 ctgattttca gctaagaaag cttttaatcc attttgggcg tctgcaacat ctttacgtgg
     6421 tggtaaataa ccagtacctt ctgtccattt agctaaagat tcaacactat aaagatattt
     6481 taagaaatcc caagttgctt cctttttctt atccgtttgt gatgtaacag ctaacattgc
     6541 gccaccagca ggtagtttaa cttttttccc ttcccaactt ggtgactcaa ctgctttagc
     6601 agtaaaagta ctattttttt gaatgttgtc cctttgagca atagtggtat agaccatcgc
     6661 gacgttacca tcaataaagc tttgcacacc ttgttcccac gtagtgtgta atgccgtctg
     6721 gtcttttacc atcctttgat ataattcata agcagcgata ccatctttag aagcaaaggt
     6781 agctttgcca tcttttatta cacttgcccc attactttct aaaattgctt gttgtgccca
     6841 attatcagca ggttcttgaa tatacacgcc atactttcca gttttttctt ttattatctt
     6901 agaaaaagtt tgaacttctt cccaagtttt tggaccattt tcatccaagc ccgctgcttt
     6961 taatatatct tgatttaaat ataaaaccgg attactaatg gagtaaggaa tacccacttg
     7021 tttaccatct ttttcagaca gtgccatgat attgtctaaa aaatgatctt taaaataatc
     7081 agcattatcc ggatccactt cttctactaa agattgagga ttagtatatt tgaaattttc
     7141 tgcaaaataa tctttaaaag cccatcccac ttgtactacg tccggtattt ctttggaggc
     7201 aacagaagct tgtaaatttt gcatcaagcc tttatacata tcaggattat attttgctac
     7261 aaccttcact ttgtcttgag attgattgta tttatctact aattcattca ctgtttttcc
     7321 acctagggta tccgcattaa catgccaata ctctatcgtt acacgaccct ccgatttttt
     7381 tgttgtcttg gtattcccac taccacaagc tgccaaagag atgacactta aaacagacac
     7441 aacccctata acaagatttt tctttaacat aacattaact tcctcctaat ttctttatgg
     7501 ccatttttct aatcaagaaa tattatgaac taccaatgta aatttctagt taattttctg
     7561 taaataattc gaaatttgtg catttcgggg tacagggtca ctggacatat ccatcaagct
     7621 aagaataaag cccccatatg gtcatgtatc ccatctccaa atctcttaac tcctctgttt
     7681 tgattataaa atagtttatt ctgtgctcct ttcttccata aataggccca tgcacaacgt
     7741 gaggttatat tataaacacc acagcgcgca aggtactcaa tcgtttctag ttcattgact
     7801 gtccatacag aaaatgtcaa tcctagctgc tgccccactt cacgggccaa cttagttaac
     7861 catccttcat gaatattgac gatttgaacg ctttgatagg ctaatttctg taaggtatcg
     7921 atcaaatctg cttcggtaat atccccaagt tttttccctt cgaactgatt ttcaatatta
     7981 taaaatatat gctttcccca aatcgcagcc caagataatt gtacatagcc actaagaaca
     8041 atttgtggcc agatttgata ggtttgtgcc agcgaaaaaa cggccatttc caatccctct
     8101 tcttttaaat cacagttaat ggtcatggtt gccttctcat tggccactgc ttgaaacacc
     8161 tgctcaaggg ttaccgaatc tgggacaact tcttacctgt catgggctag tattagcgta
     8221 ccatctgttt gctgacgcac atctacttca aaacaaagct ggcgatccaa acaaaagcga
     8281 agaaatgccc agctattctc ctccgtattg tcactaccag agtgtgcagt gatcatggtc
     8341 attttgaccc ctcctttaat tccgtgattt tctcccacac gtccactata ccgatgaagc
     8401 gttaatttct tgttaatttc ttgtaaattc cctgcgtttt ttcagtaaac tagttgtaaa
     8461 tcttgcatgc tccttcctac gaactcatga atcgtcgatt ttgcccttct agctagtttc
     8521 accaattaag tagttctaca ttccccgctt ttaacctact acaccttttt ttgttttcag
     8581 ctattccttc ttcttgctga aagtccttga ggttctttct tacaggatac catcaaggtg
     8641 ttcaatggct tattcccatt gaatgaccga gacttactat cagatttctg ctcgttgaac
     8701 caagtctttg atacaggatt tcttccgtca tcttctcaca aataccacct tgcgtttctc
     8761 tagcgattgg tcgatgtgca ccctcccagt ggactgtcac tacccctttt tgctatgcct
     8821 agcccacaaa aaaagctgtc ctcacagaca
//
LOCUS       DADVXE010000094         8700 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.097, whole genome shotgun sequence.
ACCESSION   DADVXE010000094 DADVXE010000000
VERSION     DADVXE010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.097"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            624..1487
                     /locus_tag="KB913_002586"
     CDS             624..1487
                     /locus_tag="KB913_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6820886.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1616..3238)
                     /locus_tag="KB913_002587"
     CDS             complement(1616..3238)
                     /locus_tag="KB913_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6820887.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3487..4008
                     /locus_tag="KB913_002588"
     CDS             3487..4008
                     /locus_tag="KB913_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBB6820888.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4194..5924)
                     /gene="spxB"
                     /locus_tag="KB913_002589"
     CDS             complement(4194..5924)
                     /gene="spxB"
                     /locus_tag="KB913_002589"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBB6820889.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            6089..6907
                     /locus_tag="KB913_002590"
     CDS             6089..6907
                     /locus_tag="KB913_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBB6820890.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(7010..7207)
                     /locus_tag="KB913_002591"
     CDS             complement(7010..7207)
                     /locus_tag="KB913_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820891.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7376..7954
                     /locus_tag="KB913_002592"
     CDS             7376..7954
                     /locus_tag="KB913_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBB6820892.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            8049..8186
                     /locus_tag="KB913_002593"
     CDS             8049..8186
                     /locus_tag="KB913_002593"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820893.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT         2644 a         1560 c         1698 g         2798 t
ORIGIN      
        1 aaaccgtgtc acagtccctt tttccgaaca aacggtgttc aaaagcttgc atctacggca
       61 ctaagcccaa tcagatgaaa aatatggagt gctattttta tctgattgtt cttactgctt
      121 gatgcagagc agctttttca caacctctcc actaaacggt gttctcctgc caactcctcg
      181 gtcacaagtc acaatattca acaaacatga gaagctgttt tttgaaattg ttccttgtga
      241 ctcggagcta aacggcaggc tcacaacctc ttggtaaacg gtgttcaatc agctgaccct
      301 cggtattagc tcaaaaaacg gcaaaatatg aggaactatt ttttccgttt ttttctctaa
      361 tactcaggtc aaaacgctga tttcacaacc tctgattcac ggtgttccag aagtagcttc
      421 tacggaaata agccgaaatt tcacaaaaat ttgagaagca attttcgtaa attccttctt
      481 atttcttgaa gctgaccact tctgtcacaa cctcttattt tgattagaac ttgcgaaaat
      541 aaaccggtta aagtgtgtct agcgcaagag atttgctata atagacgata agggtaaaat
      601 gtaacgagaa ggggttgaaa aatgtgtatc aaattgtaac agattcttgt tgtgatctgc
      661 cataccatgt attagcaaaa gaaaaagttg attttttatc aatgaatctc caattgaatg
      721 atcaagagtt agtagatgac ctcggaaaga cattcaatta tgaccgctac atgaatcagc
      781 tgaaaaatgg tgcgatgcct acgacatcac aaatcaatgt tggccgatat ttagaatttt
      841 tccgttctta tgcggaaaaa cagattcctg ttttatatgt ggctttttcc agtggattaa
      901 gcggctctta cagtagtgcg cttcaagcgg ttgaattgct gaaggaagaa tatgaagacc
      961 ctgagatcta tgtttttgat acaaaagctg caagtattgg ggaagggctt ttagtattgg
     1021 aagctgtaag attgaaaaaa gaaggtaaaa gcatcgaaga aaccctagag tggctggaaa
     1081 gtaattattt gaaagtccat tcatgggtaa cagtagacga tctgaaatat ctagaacgag
     1141 gcggtaggat ttccaaagca agtgctactc ttggcagtct attgagtgta aagcctatta
     1201 ttacggtgga taaagaagga aggctgacga atgttgacaa agttcgagga agaaacaagt
     1261 cgatccagac aatcgtcaat gagacggtaa aaacaatcgt tgcaccactt gatcaaatcg
     1321 tttatgtggc ttacgctggg gatctagaga gcgcggagaa ggcaaaacgg cttttggaag
     1381 agcagataaa gatgaaagat gtgaagcttt atcccttagg accaacgatc gccagtcaca
     1441 caggctatgg ctgtatcgcg attttttcga tgggaatcag tcgataaaag cagtaactca
     1501 ttctgtaaaa aagcccagaa attgattgta acaaaaacag cgactcttaa aagatagatg
     1561 agcatcctat ctcttagagg tcgctgtttt tttatttttt aagctaaata ggccattatg
     1621 cccataactc gttcaattgt ttttgaatat ctgcattttc caaaaattca tcatatgtcg
     1681 tatcagctcg atcgatcaca cctttatccg aaacggcaat gatgcggttt gccaatgttt
     1741 ggataaattg atggtcatgt gacgcaaata agattgagcc agtaaatgcc atcaagccgt
     1801 cattcaatgc tgtgattgat tctaagtcta aatggttcgt tggatcatct aatacaagta
     1861 cgttagcttt cgaaagcatc atttttgaaa gcatgcaacg gactttctct ccaccagata
     1921 aaacattcac tggtttcaat acttcttcac cagaaaacaa cattcttcct aagaagcttc
     1981 ttaagaaggt gttatcatct tcttctttac ttgcatattg acgcaaccag tctaaaatcg
     2041 ttagatcagt atcgaattct ttcgttgtat cctttggtaa ataagaatta cttgttgtca
     2101 caccccaacg tactgttcca gtatctggcg taatttcacc catgataact ttgaatagcg
     2161 ttgttgttgt tatatcattt tctgcgacga aagcgacctt gtcttctttg ctcaaattaa
     2221 aagatatatc atctaaaatt ttctttccat caatcgttac acttacattt tctacctgca
     2281 ataagtcgtt tccaatctca cgttcaggtt tgaatccaac gaatggataa cgtctagaag
     2341 aaggttggat atcgtctaaa gtaatttttt caagcatttt tttacgtgaa gttgcttgtt
     2401 ttgattttga tgcattcgca ctaaagcggg caataaattc ttggagttct ttgatttgtt
     2461 cttctttttt ggcatttgcg tttgcttgaa gtttagccgc tagttgacta gattccaacc
     2521 aaaaatcata atttcctaca taaagtttga ttttaccaaa atctagatcc gccatatgtg
     2581 tacatacttt gttcaaaaag tgacggtcat gggatacaac gatcacagta ttttcaaaat
     2641 tgatcaaaaa ttcttccagc caattgatcg attggatatc cagaccgttt gttggttcgt
     2701 ctagcaaaag aacatcaggt ttaccaaata gtgtttgtgc taataacact tttacctttt
     2761 gtccaccagt taattcactc atttgctgat ggtgcaattc ttcagggatg ttcagacctt
     2821 gcagtaaaac agctgcttct ggttcagctt cccatccatt aagctcagca aattctcctt
     2881 ctaattcagc tgctcgaata ccatcttcgt cagtgaaatc ctctttcatg taaatcgcat
     2941 ctttttcttt cagcacttca tacagacgct tgtgtcccat gatgactgtt tcaagtacag
     3001 tatagtcttc atagtcgtaa tggttctgtt tcaatacggc catccgttca tctggtccca
     3061 tagtaacgga acctgtggaa ggctgcagat cccctgataa cactttaagg aacgttgatt
     3121 tacctgcacc atttgcacca atcaagccat agcagtttcc gggggtaaat ttaatattca
     3181 catcatcaaa tagtttgcgg tctgaaaagt gcaaactcac atcatttaca gtaatcaatt
     3241 tttttcctca cttttatcat tattagtttt gacaagtctt atagaattat ataggggaaa
     3301 ggtaaaagat tcaaggcaat cgaacattct ttgtgtttca cgtgaaacag aatgaaaaaa
     3361 ataaaaataa aagcggagcg aaaatagcta ctataggatt tattagtttg caacagcata
     3421 atttttgacg ttatttataa gagggagtac tataaaactg taaaagaaat gaaagaagga
     3481 ttgaaaatgg atgaaaaaag aaccatcgac tggggctcat tgattttggg aattttattt
     3541 gtacttgtct cattgttatc atttcaagac cctgtcggaa atttagttgc aattgtagta
     3601 gtctttgcga tttttgcctt tattaaaggg atatttgaac tgtttgtacg gaacagatta
     3661 aaagagctaa caggatataa aggaaagatg cccttaataa tcgggatcat cgatattcta
     3721 gttggcgtct ttttcttatt caatattggt gcaggagtcg cagcattgcc ttttgttttt
     3781 gcagtatggt ttattgctga ttcagtttta gcgttattta ctgctgactt ggcaagagga
     3841 gtaagtgaag gatattattg gtttacgatc atcgtcaata ttttaggaat tttattagga
     3901 attttcttat tgtttaatcc aatttcttct gcgttgacat taagcttttt agttggattc
     3961 tattttatgt tatttggtat cacacatatc gtctatgcat ttagataagt aaaatcaaac
     4021 aaataaaaaa gccggcttcc gattacagtt ttactgttgt aattggaagc cggctttttt
     4081 atcatggaca aatatgcacg aggtgatttt taggtgtcga gacaaattta tgcaaaaatg
     4141 tgagaagcta tatacacaaa ttttatctta atactcgaag catagcgcag ttgtcacaac
     4201 ctcttttcat ataattcatt caatactggc aaatcatgga cttcatattt ttctttgaat
     4261 gcttggattt cttcttcaga atattttctt ggatctaaat gcagatcttc tactggcaat
     4321 gggcgcttgt tattgatctt cacatcgatt actacaggac gatctgattt tgcagctgca
     4381 tcaaaggcaa atcgaagttg cgagtattct gtgactgtaa agctatttgc cccgagcgct
     4441 tctccaactt taccgaaatc tgcatcttct aaaaatacac caaatttctt ttgttccgta
     4501 tcttcttgtt ctgcttcgat gaaaccaaaa gaatcattcg aaaagacaac attaataatt
     4561 ggaagctgat atttgacttg tgtaatgata tcttgcatga ccatagcaaa cccgccatca
     4621 ccacttaagg taaatacttg tttttctggg tagcttagtt gtgcggcaat tcctcctggc
     4681 acaccattac ccatagttgc gaaccatcca gatgtcgtat gtttttgttt accgttcata
     4741 ttcaataaac gaatagaatg gatagtcgtg ttaccgacat ctgtgacgaa aatcgcatcg
     4801 tcttcagcaa tacgattgat ttctttatag acagcctctg gacgaatcgg ttcttcctct
     4861 cgatcttcaa aagatttcaa ccaatttacc catttttctt tattttcttg atttgctagg
     4921 taccagctat cagcagggcg agcatcccct aactcgacaa gtctttgcaa agctgtgttt
     4981 gcatcaccga ggatcgacaa agatgtttca tggcgtcgtc caaattttga cgcatcgata
     5041 tcgatttgga taaattcagc agttggatta aaaaatgcac gtccaaatgg gaagtcgcta
     5101 ccgacaaata agatcagatc ggcttctgcc aatgcttcat ttccgggttt agtagcgaca
     5161 cgtccagcaa aaccaagaaa gttttcataa tcatcaggaa taattccttt tgctagaacg
     5221 gaagcgacaa caggaactga aaaatgttct gagaattctt tgatttgcgg aaatccgttt
     5281 cgcgttcctt gaccaacata aagaactggt ttttttgctt tttcaagata aggcaaagca
     5341 gctagcaaat ctttttcttc tggtaatatc acacttgttt tgtgagtgtg agcggtggag
     5401 aaaggttgtt cgtcaatttc ttcaaaacca agatcaacag ggatagtcac gatagccacg
     5461 cctttatgct cataggcggc tttaatggct tcatctacta catgcggaag actttgtggt
     5521 gtcatgactg tacgattgta tacgctaaca tctgcgaaaa taggattttc atttagttcc
     5581 tggaaagagt tatagttcat ggatgtagaa gcaacttgtc ctaagaacgc tactagaggc
     5641 acatggtcca tctgtgcatc atacaaacca ttgatcaaat gtgtcgcacc aggtcctgca
     5701 gagccgaaga cagcgccgac tttccccgtt aattttgcat ctgcagcggc tgcgagtgcg
     5761 ccgacttctt catgacgaac ttgaatgtag ttgatttcgg ttttttcttg atatagcgca
     5821 tccataattg aattgaaaga tcctccggga atgccgtaaa tatggtcgat accccagctt
     5881 tcaagaactt ttaccattgc gattcctgca ttgatttttg acatggtgtt tcactccttt
     5941 agcaatgatg atacataaat tttttgtatc tagagtatag aactttttat cgaaaatccc
     6001 aactaattcg tcttttcaca aaaatgtagt catgtttttg ggaatatgct agagtagtac
     6061 atagatagat tcaagagagg ggaatggcat ggttgaatgg ctattgagac ttgaaccttg
     6121 gcagcaagca cttgctggga cagcttttac ttattttatg acagctcttg gtgccgggtt
     6181 ggtttttttc tttaaagaaa tcaaaaaaga agtgctaaac ttgatgttag gatttgcttc
     6241 tggtgtcatg attgctgcaa gtttttggtc tttgttagat ccggctatta caaaagcaga
     6301 agaaaatgga gatattgctt ggctagttgt aagtattggg tttggtttag gcggtgtgtt
     6361 tttatatatg gcagataaaa cactgcccca tatgcatttt ggaccacaac atgaagcaga
     6421 aggattgcct acccatttaa aacggacgat cttgcttgtt ttttctatta cattgcataa
     6481 cattcctgaa ggtttagccg tgggggtagc attcggtgca gcagcaactg cggataatcc
     6541 gacagccgct atattagccg ctgtttcggt ggcgctaggt attggtatcc aaaacttccc
     6601 agaaggagca gctgtatcaa tcccgttgcg acaagaaggt ctgagtcgta aaaaggcctt
     6661 tgtttacgga caagcttctg gaatcgttga accaattgct ggagtgattg gagcgctact
     6721 agtaacgaaa gtggagctgc tgcttcctta tgcacttgct tttgccgcag gagcaatgat
     6781 ttatgtcgtg gtggaagaat tgatccctga agcacagcag acattgtcca gcaaacgtca
     6841 ttttgcagtt tttggcgtca tgagtggatt tatcattatg atgattttgg atgtggcatt
     6901 aggataaata aaaaaaatat atatgatata tcaaataggg ccgcgaactt atatcgcgac
     6961 cctatttttt tagtaagtta tatcataatg aagtgaatgg tatcatacat taataatagt
     7021 tttttctatg tgtatttcct ttgatccagc gaacaagcca gatgataagt gcgattggga
     7081 ttagaacttt gaccgcaaac cataaaagcc cgcttaggac actgacaaaa agactgatga
     7141 cgaagctagc tgcaattagc actaaaagaa ccatgaagat atttaagaac atattttttt
     7201 gacgcataca aaaccctcct cttgttcatt ctttactata gaaaaagtat aacagggatt
     7261 gtttaaaaac acctccaact gaagactgat ttttacttca tctacttaaa tgatcaaaca
     7321 attgcttttt ctctggttta tcatctaaaa tagagcggaa aaggaggaga atatcatgcc
     7381 taaaaatcgt cttgaagcat ttacagatgc tgtaatcgcg attatcatga ctattttagt
     7441 tttagaactt catgaaccta acggagacac gtgggaggcg ctcgctgcat taggttaccg
     7501 attttttatc tatattgtca gttttatcat tttagcgatt tattggaaca atcatcatca
     7561 tttatttcaa gttgtacata agataaatgg acgggtctta tgggcgaaca gtttctttgt
     7621 ttttgcgctt tcgctttttc cgtttgcaac ttcatggatc agtgagtaca tcaatagcct
     7681 ggctccagaa atgacttatg gttttgttac cttgaccgct aatattgcgt attatatctt
     7741 ggcaaaagaa cttgtcaaag caaataaagg ccacgagaaa gcattgaagg cgatgttgaa
     7801 taattacaag aaatcgtatc tatcgattgg tttgaatgtg ttaggaattg tcttagggta
     7861 tttagtagcg ccagtagccg tgctgatcgc aaacatcgtg attctagctg cttggatcat
     7921 cccaagtcgt accatcgaat cacaatatcg gtaaaatgat ccgtgtttaa aatttaagag
     7981 aaaaatatag aaaaaataaa taaacgatca aatatccgag tgatactagt attcaaagag
     8041 ggatgcagat ggatcaaaaa agaattcatg taggactgat tactagtttt gtcacgatgc
     8101 ttatttattt ggatcaaggt catttgactt ggacagtagt tggtgtcgta ggatttttga
     8161 cattattcac agcaataaaa aaataaacat ctttatgtaa tctgatgttc tatctattta
     8221 agaaaagcat gtttacagca gtatgattct gttgtaaacg tgtttttatt tgtggaaaat
     8281 ttaattttta gaaaagtgta tcgaaaaata gatagttagt ttttccacag tggataactt
     8341 cgtaagagat aaaaataaaa aattagtcaa agaagggcgt atagatttct tttgatagga
     8401 gatatacaac agaaatgaat aaatattaac gtgttttcaa acagtataaa acggtgtggt
     8461 ttttggaata aaaaaataac atatctcatt ttacactttt gttattttat acttaaaaaa
     8521 taacgacaca gaaaataccg tgtctcagat ttctctacta cttctaaaaa ctactgtttt
     8581 tttcctttga aatgccttca aaaagtagga tcaggcagaa tatactggca gaatcaagga
     8641 gaagggagcc taaataagga gaaaaaccat agaaaatata aagtaattac ttataaaaca
//
LOCUS       DADVXE010000095         8565 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.098, whole genome shotgun sequence.
ACCESSION   DADVXE010000095 DADVXE010000000
VERSION     DADVXE010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8565
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.098"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(163..2544)
                     /locus_tag="KB913_002594"
     CDS             complement(163..2544)
                     /locus_tag="KB913_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBB6820894.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2534..3181)
                     /gene="recU"
                     /locus_tag="KB913_002595"
     CDS             complement(2534..3181)
                     /gene="recU"
                     /locus_tag="KB913_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBB6820895.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3245..3784
                     /locus_tag="KB913_002596"
     CDS             3245..3784
                     /locus_tag="KB913_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBB6820896.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            3874..4293
                     /gene="gpsB"
                     /locus_tag="KB913_002597"
     CDS             3874..4293
                     /gene="gpsB"
                     /locus_tag="KB913_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBB6820897.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4315..4682
                     /gene="rnpB"
                     /locus_tag="KB913_002598"
     ncRNA           4315..4682
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KB913_002598"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            4891..6057
                     /locus_tag="KB913_002599"
     CDS             4891..6057
                     /locus_tag="KB913_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBB6820898.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6103..7599
                     /locus_tag="KB913_002600"
     CDS             6103..7599
                     /locus_tag="KB913_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBB6820899.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            7680..8363
                     /locus_tag="KB913_002601"
     CDS             7680..8363
                     /locus_tag="KB913_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6820900.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         2678 a         1565 c         1823 g         2499 t
ORIGIN      
        1 ggattttcta atttttaagc taaatgttag atcacacatg tatatgctgg atagtcttat
       61 aaaaaatcat gtaatacagc ttggtacatg atttttattt gtagctgttt tttacataga
      121 cacaaaaaag aaaccacgct tgtagacgtg gtttcttttt tactatctgt ttccagaagc
      181 tgaggtgctg ctggatggtg tatggtcatt tgcagcatcc gctccgctag ttgctggctc
      241 actggaagaa gcaggaggag cagatgaaga cggtgtcgag ctttcttcgg atgaagaaga
      301 aggaaccgtt gttgaagacg ctggctcgct tgtttctgct gtcgtgcttt cttttgagga
      361 ctcagcagtt gattcgcttt gactagtaga gctagagctt tgagtcgttg tctctgttgt
      421 tgagcttcca ggagtctgga catagctgga agatggaata gttgttgatg gtgtaattgc
      481 attcgatcta gctgtatatt gatctttgta gtacagttca ccgcccacac gaattaatcc
      541 gcttggcatc tcccagtctg tatttgtcac gttagctgaa acatactgca taagctcgcg
      601 ataaacatca gaggctacgt gtgacgattc tgaagtgaca ggcgtcattt ttttattgta
      661 acctgtccac acggaaatcg aataatttgg cgtatagccc gcaaatagga tatctggata
      721 caccccagaa gaaataccaa gttttgcata ctcgtcatct gtgtaattgg atgttccggt
      781 cttaccggct tgatataacc cagcgatttg cgcattcgta ccagttcctt cagtgatcgt
      841 atcttttaaa atgtctgtga tcatataagc tgtttctgga gacatggctg tttttccatc
      901 tggctcataa gtttcttctg ttccgtcttg gaagacgatt ttattaacat attgaggttt
      961 gtaataagtc cctccattgg cgaaagccgc ataggctgct gccattttta aggaagaagc
     1021 tccgtatttt gtcccatctt gttcttccgt attactagag atcgcattcg attgatggat
     1081 cgtactgtat tcgatcccaa gattttttaa gaaagaagcc actttatctg aaccgacttc
     1141 attgaataat ttgactgctg gaacattacg ggataagtaa agtgcttggc gtaaagtaat
     1201 ggtgcccata tattgattat cccagtttcc tacaggagtc gaagtccctt catagttata
     1261 cggtgcgtca gtaatagttt ttccagtaga atatttcaaa tattcaaaag ctggtccgta
     1321 atctgtgaca ggtttcatcg tagaaccaaa atcacgggaa gtattcactg ctaagttgtt
     1381 gcctaaagtt acgtcttctg cgatgtgacg tccgccaatc tgggctttta ctttcccggt
     1441 attggtgtcg ataagggtgg aggcaacttg catctcgtcg tctgggtaag agacatactg
     1501 atccgtgttg acgatatcat atagtttctt ttgggcgtcc agatccaaat tcgtataaat
     1561 ctctaaaccg tctgtgtaga cattcttatc tgttttttct tgtacttcat tgatgacttc
     1621 tttgacataa ttatcgacga tcttagtatt gtcatcggat tgagttagtt cttgcagacc
     1681 atccgttacc ggtacattaa cagcttgatc atattctgtt tgagagattt tttcgttttg
     1741 aagcatcgta tacaaaacag tatctcgtct tttcttcgcc tgatctggat aaacataagg
     1801 atcataggcg gaaggggctt gaggcatccc agcaagcaat gctgtttgcg gtaaagaaag
     1861 ttctgataat ttcttaccaa agtacatctc agaagctgtc tccatcccgt acaagccgtt
     1921 tgacatatac actttattta cgtagtaggt caagatctct tgtttcgatt ttttttgttc
     1981 caatcttaca gccatccacg cttcttgggc cttgcgtttc agagtctgat cctcggcact
     2041 ggtggagaag aaggaaagtt tgatcaattg ctgtgtcaaa gtacttccgc cttgcagtcc
     2101 gccagaggta aagttagaga gggcagaacc gatgatccga atagggtcaa ccccgatgtg
     2161 tttataaaaa cggcgatctt ctaccgacac gatcgcatct tctaatgttt tcggtaattc
     2221 attcgcagaa attttttcac gcttttctgc gcctaaatct tcgaatagtt cgccatcttg
     2281 tgtatatagt ttggaagata cggtagcgtc taatttttta tccgtcaatt cgggcgcatc
     2341 ttttgcgtaa taccagaaaa gtcctacacc tgctaaaaag aggatacaga aaaatgagag
     2401 tattcctaaa aggatcttga taaataatcc ttttttatgt gttccagagg actttccaga
     2461 acctttgcca gaattcttct tcacactctt tttaggagta ggctgtttct gtcgtctaga
     2521 gcttctagtt tgttcatttg ccattcttgc tttctccttc aatagataat gttgataaat
     2581 agaagtcaac cgcgtccaaa taaggaatcc gcggagaaat accagttttg atctctattc
     2641 ctagttcttc gatcaaagat aaaggtagtg atttgcgtcc tttttccttt tgggcgtccc
     2701 agtaagcaat caaatgaaca ctattcaaat aaaaacagcg cttcaaagac gaaaaccata
     2761 acaagacaaa gcagacccca ttttgttcga ggcatgcttt catatgttcg atttgatggg
     2821 catggaagtt tttaaaggga aaagatgttt tgttcttggt ttcttttgct tcaaagtcca
     2881 agtaaaagcc tcgatagacg ccattatagt ctgtagttga ggcttgggta aagtaggctt
     2941 ccttgatcac agcagcactt ctcttaggat agtctacttt cacgatttgg ataggggtag
     3001 gctttttatg gataaccgcc aacccgcggg aaagataata tttattactt tcattgattg
     3061 cttcttcaaa gcgcatcccc cgattgccga attcagtgat ctgatttctt ttttcttgaa
     3121 ttttttcgac gggagaggca ttcttataat aaggttggcc atttggatag cgcaatacca
     3181 tctttaatca cactcctagg ccacattata gcaaaaaagc ggatagaaag aaaaggaatc
     3241 tgagatggat aagtcaaaag taatctatgt gtctgggtat cgaagtttcg aactcggtgt
     3301 ttttaaagaa aatgatccta aaatccaagt tgttaaaaat gttttaaaaa aagaactcca
     3361 tcagttagca gaagaagggc tggaatgggt acttgtcagt gggaatttgg gcgtcgaact
     3421 atgggctgtg caaatagtag cggaattgaa agaagaatat ccggaactat ctcttggtat
     3481 tttgtatcct ttttctgatt ttggtaataa ctggaatgaa gggaaccaag aaaaaaaaca
     3541 attagcagaa caattagcag attatgtcga agctgttagc catcaaccct accaatcacc
     3601 tagtcagcta aagaatcaca ctcgttttat acttgagcat acagtgggct gtctgctgat
     3661 ctatgatgaa gaattccctg gaaaaacgaa gtattttttt gaagatgcac agaattacca
     3721 agcagatcat ccctacgaaa ttcggctgat cagtatggac gatcttcaaa attttagtga
     3781 ataatcgata ttgtgtttga tttatcaact tttttcctat acaatgaaaa aggtagaaat
     3841 gttattacgt aaatgaaaac tagaggtgta aatatggcga atttggttta tagtcctaaa
     3901 gacattttac aacaagaatt caaaacaaaa atgcgcggct atgatcccgt tgaagttgat
     3961 gaattcttag acaatatcat caaagattat gaaacttaca gcaaagaact ccttgcttta
     4021 caagaagaaa acgatcgatt gagtgcaaaa gtagctcaat tatctaaaac tcaaggagca
     4081 gctcaaacac gcgtgcaaca aacagaggca ccaaagagcg cagcagtgac caattttgat
     4141 atcttaaaac gcttgtcaaa tcttgaacgt gaagtatttg gtaaaaagct tgatcaacaa
     4201 gcaagtgcag tcaaaccagc acaacctaat ccaaataact acacaaatgc agacacaagc
     4261 ttagatgata atgaaaaaac acgtcaattt taatttttga ttaatgaatt tgcggttttc
     4321 gggtaatcgc ggtctgactt gatcaggctg aggaaagtcc atgctcgcac aggctgtgat
     4381 gcctgtagtg ttcgtgctta gcgaaaccat aagctaaggt actctttgga gtaacggcag
     4441 gaaaacaagc taaggcttcg gctatgctta agtatccttg aaagtgccac agtgacgaag
     4501 cggctgggga aacccatccg gtggaacgcg gtaaacccct cgagcgagca acccaaacaa
     4561 tggtaggggc gctttttgtc tggaagaaga acaggacaaa aaggcagtat aactgcagat
     4621 agatggttac cgctttgttt tttctccctg gaaaagcaaa gtacagaaca tggcttatag
     4681 aaaaccgcaa acatcaggga attaggtcgt gacaaaagta atgcgttata agaaacaaga
     4741 aaaacatttg aaagctattt ttcaatactt cagatgaatc gttcttatta caaaacaaac
     4801 ttttgtatca ccggttattc ggaatttgag taaaagtgtg gggtaggact gatgtcccac
     4861 ctcctttttt tataaataag gagattgtgt atggaaaaaa acaggaagtt caacctcgtc
     4921 gcaactgcgg caagcgggct agaagcactg gttggtaaag aattaagaga tcttggaatc
     4981 gaatgccaag ttgagaacgg acgtgcacgt tttgaaggaa caatggaaac gatcgctaca
     5041 gctaatttat ggttacgtac agcagatcga gtaaaaatcg tggttgggga attcgatgcg
     5101 tatacgtttg atgaattgtt tgaaaacgta aaagcattgc cttgggaaga ttttcttcca
     5161 ctagatgcag cttttcctgt agctggaaaa tcgatcaagt cgaaactata tagcacacct
     5221 gattgccaag cgatcacaaa aaaagcaatc gttgaacgtc tccgtaccta ttatcaccgt
     5281 ccagcttctg taccactgac ggaaactggc gcacattttc agttggaagt agctttgctg
     5341 aaagaccatg tgatggtaac tctggatacg acaggaccaa gtttattcaa acgtggttat
     5401 cgcttagaaa aaggtggagc accattgaaa gaaaacatgg cagcagcact tattatgttg
     5461 acaaattggc gaaaagaccg tccattttat gatcctgtat gtggttcagg tacgctttgt
     5521 attgaagcag ccttaatagg ccataatatc gcaccaggat tcaatcgtga gtttgcttgc
     5581 gaatcttggg attggttcag tcaagaaatc atggaaaatg ttcgatcagc agccgaagaa
     5641 aaagcagatt atgatattga attagatatt actggttcag atatcaatgg acggatgatt
     5701 gaaattgcca aagccaatgc agaagaaatc ggattaggct cttcgattac ctttaagcaa
     5761 caagcagtca aagacttcaa aacggataaa gaatacgggg tcatcgtggc taatccgcct
     5821 tacggagaac gtctaggaga agaagaaact gttcggaaat tatataaaga aatgggcgat
     5881 gtattccgtc cattaaaaac atggagtaaa tatatcttga ctagcgactt agcgtttgag
     5941 gaattttacg gacaaaaagc aaccaaaaaa agaaaattgt acaatggtgc attgcgtacg
     6001 gatctattcc agtattgggg aactcgtccg cctagaaaaa aagagaaaga cgaataatct
     6061 tactaattga ttcattcaat tggatgtttg gaggaatagg gaatgaaaga aaaagagttt
     6121 ttacaagaag taaaagaaat caatcttcta caacaagctt taggaatcct cgattgggat
     6181 acacaaacag gtatgcctga aaaagctagt gcataccgaa gtgaagtaga cagctatctt
     6241 tacagcattt atttttcaaa aaaaatcggt ccaaaaatca aagaagccat tcgctatttt
     6301 tctgaacatc cggaagaatt gtcggaagtt ggaactgccg tttttgccaa agtaaaagaa
     6361 gagtatgatt tggaacatcg cgtaccggaa gatcttatga gaaaatatac agctgccgtt
     6421 tcttcagcac acggacaatg gcaaaaagct agagaaacac aacaattttc tgattttcaa
     6481 cacgcattga atcaaaatat tgaattaaca aaacagttga taccttactg gagaaaagat
     6541 gaaaagacga attatgatgt tttgctgaat caatacgaac ccgggatgac tgtcgaaatc
     6601 cttgataagg tatttgatca gcttaaagaa ggaattcttt cgatccgccg tacgctccaa
     6661 gaaaaaggga ctgaacctga aacagacttt ttaaatcgga gaatgacgaa aaaacaacag
     6721 aagagatttg tagtgaaagt aatcgaacaa cttggttatg attttagtcg tggtcgttta
     6781 gatgacactg tccacccatt tatgactgga attaatccga atgatgcacg aatcacgaca
     6841 cgatggaacg aaacagattt caaaatggct gtttttggag tgatccacga ggctggtcat
     6901 ggtatgtatg aacaagacat cgatgataaa tatgcgtata caccggttta tgaaggtaca
     6961 tcaatgggta tccatgaatc acaatcgttg tttaacgaga tcattattgg aagtagtcgc
     7021 agcttctgga aaaagcaata tcctttcttt caagaatgtg cagaaggaac attcgatgat
     7081 attccttttg acaaatttta tcgttcattg aaccatacaa aatcaagttt ggttcgtatc
     7141 gaggcagaca gtttgactta ccctctccat atcatcattc gttatgaaat cgaaaaaatg
     7201 attttcaatg aaggggtaga tgttgctgaa ctacctgaaa tatggaatca aaaatatgaa
     7261 gagtatctgg gaatacgacc aacaaatgat gtggaaggca tcctacaaga cgttcattgg
     7321 tcaggtgcaa gctttggtta ttttccctct tatgcattag ggtacatgta tgcggcacaa
     7381 ttacttcatt ctttgcagca agaaatagat gtggaaaatg ttctagcgtc agacgattat
     7441 tctccaatca aaaactggat gtcagagcat atccatcaat atggtgcatc tagaaaacca
     7501 aatcaattaa tcatggatgc aacacatgaa ccgcttaatc cgcaatacct gatcgactat
     7561 atgaaagacc tgtattttaa tgtatatcag gtaaaataaa atacaattta caaagatagc
     7621 tgaaattcat ctaatctata gatgttttca gctatttact taagaaagaa gtggaacgaa
     7681 tggataaatt acaagtgatc gctgattata gtatggacca attagcgcat gatcaaacag
     7741 gacatgggag cgatcatacc aaaagagttg tcaagttagc tgaaaaaatt ttggagacgg
     7801 aaccgcaggc agaccgcttt gtgacgcttg cagcagctta cctacatgat acgattgatg
     7861 ataaagtcgt taaaaatgag aacgaggcaa agcaacagct tcgtgtattc cttcgctctt
     7921 tgccaatagt agaggaacag atctcgatga ttttttccat tatcgaaaat atgtcctttt
     7981 ctaaaaatct ctctgaagcg gccgaactat ctctggaagg taagatcgtt caagacgctg
     8041 atcgtatcga agcattagga gcaatcggca ttttgcgtac tgcttatttc ggcggtggac
     8101 atgggcaccc gatttttgat cctgaactgt atccgcaaac attcaaggac aaagaaaatt
     8161 accgaaaagg cacgacagtg atcaatcatt tttatgaaaa actgttcttg ctgtctgata
     8221 aaatgaatac tgattacgga tatgaagaag ccaaacgaag agaaaccttc atgcgtgaat
     8281 tcttagaaga attttttctg gaatggtcta ttgacgatga aaattttact ccagacaatt
     8341 ggatcaaaaa taacaaaaaa tgatggaggt tgtgacagaa gtggtcagct ccaagatatt
     8401 tcggatcatt ttccgtaaaa gttacttctg gaacactgtt taccaagagg tcgtgagcct
     8461 gccgttcagc tccgagtcac aaggaacaat ttcaaaaaat agcttctcgt gtttgatgaa
     8521 tattgtaact tgtgattcgg aattggcagg agaacaccgt ttatt
//
LOCUS       DADVXE010000096         8127 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.099, whole genome shotgun sequence.
ACCESSION   DADVXE010000096 DADVXE010000000
VERSION     DADVXE010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.099"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(129..311)
                     /locus_tag="KB913_002602"
                     /pseudo
     CDS             complement(129..311)
                     /locus_tag="KB913_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            298..495
                     /locus_tag="KB913_002603"
     CDS             298..495
                     /locus_tag="KB913_002603"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820901.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            complement(538..1113)
                     /locus_tag="KB913_002604"
     CDS             complement(538..1113)
                     /locus_tag="KB913_002604"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBB6820902.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(1268..1794)
                     /locus_tag="KB913_002605"
                     /pseudo
     CDS             complement(1268..1794)
                     /locus_tag="KB913_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2251..3762
                     /gene="gadC"
                     /locus_tag="KB913_002606"
     CDS             2251..3762
                     /gene="gadC"
                     /locus_tag="KB913_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HBB6820903.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            3775..5175
                     /locus_tag="KB913_002607"
     CDS             3775..5175
                     /locus_tag="KB913_002607"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBB6820904.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(5340..6775)
                     /locus_tag="KB913_002608"
                     /pseudo
     CDS             complement(5340..6775)
                     /locus_tag="KB913_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            7168..7761
                     /locus_tag="KB913_002609"
     CDS             7168..7761
                     /locus_tag="KB913_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBB6820905.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVSGGMATVFLTNF
                     IRCRTSFRMLFRLSLTMSLLGCDDLRQELTVKVRLPR"
     gene            complement(7745..>8127)
                     /locus_tag="KB913_002610"
     CDS             complement(7745..>8127)
                     /locus_tag="KB913_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBB6820906.1"
                     /translation="FSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKG
                     CPFDNAVAESTYKSLKVEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVG
                     YRNQRLAQRILDNELGCANASEAV"
BASE COUNT         2541 a         1394 c         1480 g         2712 t
ORIGIN      
        1 ttcaataaaa atatattaca ataataatcg taatagctaa tgaaacaatt tctcaatctt
       61 tttaccactc caaacaggga gcgtcaataa ttttgtgtaa ataactcgtc cttctgcaaa
      121 ataatgggtt actcagtaaa cattgaagct aatgtatccg tcacttgttg gaagccttta
      181 tggcttctat ttaagaattt ttgattgtat gtatcaaaga tggatactag gaaacgctct
      241 agtgattctt cattttgaaa ctgctctttt ctgcggctgt atttcttgat ttgtttattg
      301 aaagattcga ttgtagaacc agaaggaatg gagaacactt ttgaacttta caacaaaact
      361 actgttgata aattaattcc aattttagtt ccaactgatt taaatggtca tgatgtttta
      421 cttcgtttta acggattttt aggtgaggat tatagatacc taaaaatttc tgatcctcaa
      481 cctttaacag aataataaaa aacgtgtaat caattatttg attacacgtt ttttatttca
      541 atcttcgttg tagtagtggt tgcgacatac cgaaaggtaa tcttcattac ctcctactac
      601 aatctgttca cctgaataaa ctggaatacc atcaacaata cgagcattca ttacagcctt
      661 tttattgcaa aaatggcaaa tagttttaat ttcctcaatt ttatcagcaa atgtcaataa
      721 tgcttcggat cccttgaaga gattattttg aaaatcattc ttcaatccat agcaaattac
      781 tggtacttcc tcattcatta cgataagtga tagatcaata atattctctc tacttaaaaa
      841 ttgagactca tcgaccaaaa tacaatcaac ttttccgtac tgatcaataa tctccactaa
      901 ttctccgtac acatccattt cagaagtaat tgcaatagct ggtttcgaaa cacctatacg
      961 actctcaact tttccaaatc ctgatcgagt atctattgcg cttgtcatta tgataactct
     1021 cttcccttgt tcttcataat tatgagccac tttcagtagc tcaatactct ttccactatt
     1081 cattgttcca tatctgtaaa ataattgtgc cattaaattt attcccttct tttacaattc
     1141 aattattcct taattccatc tgcttttatg cagctgctcg tttattcctt gatatgtcta
     1201 taacatctac tatccctaaa accaatttat aagccattag agatggtatt cctgaacatc
     1261 tctcatattg ttttttgagt ggtatatcat ctgaaaaact gaaggaatca tgaaaatagc
     1321 gacatactta tcatttagag ttctaacttt aaatgcattt acttcttcag tcagcacttt
     1381 agtcatgttg gacatggttt ggggcgtgta gtgatgccca tacattttct caatcaagtc
     1441 tgcgatttcc gacatggtaa taccttttcg gaagaggtga atgacggtct cctctaatgt
     1501 gtcattcgtc cgtctataag caggaacagt ctgttgcttg aactcgccat tgcggtcgcg
     1561 cggaatctgg agatgaagtt ccccatactc ggtcttgacc gtacggtcat aggagccgtt
     1621 acgagaatta cccgtgttaa aaccaatgcg atcgtacttt tcgtaatcga ggaaagccgt
     1681 taactccgtt ttgagaagcg tattgacagc tttttccaaa tggacacgga ataatccatt
     1741 caaatcgcct ttgttcgcta gagtctttag gatttctgta gtaaaatcgt tcatatggaa
     1801 gtcctctttt ctgtgaatgt gttgtggtaa ctctattcta cagaagggac ttcctttttt
     1861 ctatttacac aaaatatttt acactctcaa caaaagtatc ttcgattaat acttgctcaa
     1921 gttatgtgca gctacgaaaa agtaggtacc gaggtacttt ctttttcgca gctttttttg
     1981 gacttatgag aagtacattc gctggaagaa tacgatataa aacgagcttt ttcactaaag
     2041 atattaatag agtgaaagaa acaagctttt gttgtcagtt ttttcacttt tctaaaaatg
     2101 aaaataaaaa attctggaag tggagaagaa ttttgcttgc tatactttgt cttgtagaaa
     2161 agaggtagac aaaataatgc aagctcaaat aagcgatttt ccataacctt ggtaggaatg
     2221 acaaattaaa taggaaaggg aagtaataat atgaataaaa aaaagttatc tctattcggt
     2281 ttttttgccc tgacagcttc catggttttg actgtttatg agtatccgac ctttgcaaca
     2341 tcacaattac atttggtttt ctttcttctt ttgggaggta ttttatggtt tctaccagtt
     2401 gctttatgtg ctgcagaaat ggcaacagtt gaaggatgga aagatggtgg gattttcagt
     2461 tgggttagtc aaactttagg agaacgtttt ggttttgcag ctattttttt ccaatggttt
     2521 caaattacag taggttttat tacaatgatc tacttcatac taggagcgct gtcgtatgta
     2581 attaattttc cagagcttaa tacagatcca tttatcaagt ttattggtgt attagtcatt
     2641 ttctgggtac tgactttttc acagttgggc gggaccaatc gtaccgctaa aattgctaaa
     2701 gcaggatttg tcattggaat tgttattcct tcgatcattc tctttggttt agcagcagcc
     2761 tactttatcg gcggtaatcc gattcaaatg gctattaatg cgaaagcttt tattcctgac
     2821 ttttctcagc tttcaacttt agtagtattt gtatctttta tattggctta tatgggcgta
     2881 gaagcttcag catcacatat taatgagctg gaaaatcccc aaagaaacta cccattggca
     2941 atgtttttac tagtgatttt ggccatcgcc ttagatgcaa tcggcggttt ctcagtagca
     3001 gcggttattc cacaacatga cttgtctctc agtgctggtg taatccaaac atttgaaacg
     3061 cttattttac attttaacag tcatttacat tggttggtaa aagtgattgc tctcatgatt
     3121 gcctgtggcg ttatgggtga agttagttct tgggtagttg gtccatcacg agggatgttt
     3181 gcagctgctc agcgaggtct gttaccagtt ttcttccgga aaactaataa acaagacgtt
     3241 ccagttccgt tgattatgat acaaggaatt atcgttacta tttgggcagc agtcttaact
     3301 tttggtggag gaggcaacaa tttatcattc ttagtagcaa tctccttaac tgttgtcatt
     3361 tatctcgtag gatatttact atttttccta ggttactttg tattagtttt taagaaaaaa
     3421 gacttaaaac gaacttacaa tgtaccagga aaaactgttg gcaaaacgat tatcggtgga
     3481 attggtttta ttttatcagt gttcgcattg cttatctctt ttgtaccacc agcttcaatt
     3541 gcagctagtg agcaccgaac ataccaaatc atactactta ttagctttgt agtgactgtt
     3601 cttttacctt ttatcattta tgaagtacat gataaaagtg ctcacacaac tattgaggaa
     3661 cctactcacg tgaaagctga agacgttaat cccgctgttt atccagctgc tagaggagag
     3721 caccacgtta caaaaaatga tgaacatatt ttaaaacatt aggaggaatt cattatgtta
     3781 tacggaaaag ataatcaaga agaaaaaaac tatttggaac caatttttgg ctctgcaagt
     3841 gaggatgttg acttgcctaa atataagtta aacaaagaat ccattgaacc acgaattgct
     3901 tatcaattag tacaagacga gatgttggat gaaggaaatg cgcgattaaa cttagctact
     3961 ttttgtcaaa cgtatatgga acctgaagca gtgaaattga tgacccaaac gttagaaaaa
     4021 aatgcaattg ataaatcaga atacccacga acaacggaaa ttgaaaaccg ctgtgtaaat
     4081 atgattgctg atttatggca tgctccaaat aatgaaaaat tcatgggaac ttcaacgatc
     4141 ggctcttcag aagcctgcat gctgggtggt atggccatga aatttgcttg gcgtaaacgt
     4201 gctgaaaaat taggtcttga tattcaagca aaaaaaccta acctggtgat ctcttctggt
     4261 taccaagttt gttgggaaaa attctgtgta tattgggatg tggaactgag agaagtccca
     4321 atggatgaaa aacatatgtc aattaatcta gatactgtca tggattatgt ggatgagtac
     4381 acaattggta ttgtaggtat tatgggtatt acttacactg gtcgttatga tgatatcaag
     4441 ggtctgaatg atttagttga agctcacaat aaacaaactg actataaagt atacattcat
     4501 gttgacgctg catcgggtgg cttttatgca ccatttactg aacctgatct agtttgggat
     4561 tttcaattga aaaatgttat ctcaattaat tcttcaggtc acaaatatgg tttggtatat
     4621 ccaggtgtgg gttgggtctt atggcgtgac caacaatact taccagaaga attagtattt
     4681 aaagttagtt acttaggtgg agaaatgcca actatggcta tcaacttctc tcatagtgca
     4741 gcacaactaa ttgggcaata ctacaacttt gtacgctatg gctttgatgg ttatcgtgat
     4801 attcaccaaa gaactcatga tgttgctgtt tatttagcca aagagatcga aaaaactggt
     4861 atttttgaaa tcattaatga tggatcagaa ttgccagttg tgtgctataa gctgaaagaa
     4921 gatcccaatc gcgaatggac actatatgat ttatctgatc gtctgttaat gaagggatgg
     4981 caagtcccag cctacccatt acctaaagac ttggatcaat taattattca acgcttagtt
     5041 gttcgagcag actttggaat gaacatggct ggtgattatg tacaagatat gaaccaagca
     5101 attgaagagt tgaataaagc tcatattgtt tatcataaaa aacaggatgt gaaaacgtac
     5161 ggctttactc actaaaattc ttcagagaaa tataaaagaa gttaattaac taataaaagg
     5221 agttgtgatt accacacagc tccttaaatc tatttgaata aatatatgat attcatttgt
     5281 tacactctca atcttagctg ttgttctatt catcattact cttattgtaa gtagttcagt
     5341 caaatttgct tgttcaattg atcgataaca gtatgaattg tttgaaaagt aatcggatat
     5401 ataattgttt tctcactacc taagccttct tggtataaag aactatcgca aagtataatc
     5461 cgctgagtac aaaagaaagt gtcgtctact atttctctaa gttgtttaca aatgatatta
     5521 ctaatagaaa agtgttctcc caaaatgtct tctaactgtt gtcgatagta taaataccta
     5581 aagtctgacg gagctactat gaacacttca attggagatt tccgtttatg ctcatttaaa
     5641 agacttaaac taatggttag tttacgaata gaattctcat tccaacgcag aaataaattg
     5701 ttttgttttc gccattgttc aagaatttca tgaacttcta agtacaaagc gcgttgctct
     5761 tcatttaaca agtaagtctt atcaggttga aatatctgaa tatcagccca aagtgagcgg
     5821 ataaacggga gaagtgcttt atcaaaaagt atctgatttt cttcagatat attcagagat
     5881 aagataagtt tttgactgag ctcaatcacc aaagggttat ctgctacatg gttttgataa
     5941 acaacgttca agtctttttg taacaattca aagttatcgc atagataatt tctagagttg
     6001 aatagaaagt agatataaag gcattcatct tcgtcatgac ataaagagaa agaaagttgc
     6061 tctaatcctt tctgtattag ctgaaacaag ggagtatgtc gggcaactct tttttcttcc
     6121 tgactaaaat atattgggtt agtcttagat ctctgcaaac cgatagcgat acctaataaa
     6181 ataaattgtt tttcaactgt agggtaactt cttgaaaaaa atgtttttct acataatcaa
     6241 tcaattgttg accgctttga ataattgatt tatttagctg gatcaactct gtccgatttg
     6301 tctcatagat tatcgttagt aacaaacttc gataatcctt ttcaggaatt tcaaaatggc
     6361 catcagcatt taagtactgc atttgtttaa aaaaattaat caactcattt cgtaagttgt
     6421 aaactttgct taacgaaatg aaggtagtat cagctatatt actccaattg tgttcccctg
     6481 ataaataatg tcctagtaca ttgaaaaagt cagagcgctg atagatgagt tgagtgagtg
     6541 ccaacctcga aaacgaagag tcgaatgcga ctgtaaagct acttctagat ttctccactg
     6601 aaataatttg ctgatggagt atgtcggtaa tgcattccaa gtcgttagtg acagtgagtg
     6661 ggcaaacgtt caattgatct gctatttcgc gaatctgaat ggtccctttt tcgtgtaatt
     6721 gctcacaaat gtaaacttga cgaaaaatac ttttctccag ataggtttcc aacatagtac
     6781 tcctcctagt cattttatac ataactatta taactctacc aatcggaata gtcctgtaat
     6841 atattgaatc aaaaatataa attataaaat aattagatgg ggtatttggt ttaagtatcc
     6901 cttatatagt aataaattta taggtgtgat tctcgaatta atacccgaaa atgtgagaga
     6961 atttttatgg attttttagg atacaaatta attatttttg cttttatcct gattaccagt
     7021 ccagtactgt cggtatccca ttttgcagca aaatcatgtt gataaagtga caagaagact
     7081 gatgagatat attatccaaa ttgagaagat aattaatcgg attcttgagt ataccctact
     7141 ttttaagaaa gtagggtata caagcgtatg aataaagaca taactttccc tgtgatggac
     7201 gttcggcttg ttccaattac caaaatacag gcgaacgatt ataatcccaa tcgagtagcg
     7261 tctccggaaa tgaacttatt ggagctttct atcattgaag atggctttac tcaaccatta
     7321 gtttgttatt acaaggaaaa agaagagaag tatatcttgg ttgatgtgct tcataggtat
     7381 cgtgttgcta aggaaagact caacttaaaa gttgtaccgg taacagttat tgataaaccc
     7441 atagaagaac gtatggcttc aacaattcga cacaatcgtg caagagggac ccatgaaata
     7501 agaggaatgg aaattgtcat ccaaagatta gtaaaaaatg gatggtcaga caagagaata
     7561 tccaaagaat taggcatgga cattgaagaa atttttcgct ttaagcaagt gtctggtgga
     7621 atggcaacag tttttttgac aaattttata aggtgcagaa cttctttccg tatgctattc
     7681 cgattgtcct tgacaatgag cctcctcgga tgtgacgatc ttcggcagga gctaacagtt
     7741 aaagttagac tgcctcgcta gcgttagcac atccgagctc attatcaagg attcgctgcg
     7801 ccaatctctg gttacggtaa ccaaccggtg tctcgtagcc aagtgtaccg tgcaaccgaa
     7861 ggtggttcca ccaatttaca tagtcaaata actccaaatc caattgttgt aaggtttcaa
     7921 atgtgtattg atagacaaat tctactttca acgacttata agttgattca gctacggcat
     7981 tatcaaaagg acagccttta tgactcaatg atcgattgat gtcaaaagtt gttaataatt
     8041 catcaatagc ttggttatca aactcttttc cacgatcagt atgaaaaatc tcaacctctg
     8101 tcagaggttg tttgatacgg ctaaatg
//
LOCUS       DADVXE010000097         8092 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.100, whole genome shotgun sequence.
ACCESSION   DADVXE010000097 DADVXE010000000
VERSION     DADVXE010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.100"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..739)
                     /locus_tag="KB913_002611"
     CDS             complement(<1..739)
                     /locus_tag="KB913_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6820907.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGA"
     gene            complement(859..1506)
                     /locus_tag="KB913_002612"
     CDS             complement(859..1506)
                     /locus_tag="KB913_002612"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HBB6820908.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(1590..3017)
                     /gene="uxaC"
                     /locus_tag="KB913_002613"
     CDS             complement(1590..3017)
                     /gene="uxaC"
                     /locus_tag="KB913_002613"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBB6820909.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(3091..4170)
                     /gene="uxuA"
                     /locus_tag="KB913_002614"
     CDS             complement(3091..4170)
                     /gene="uxuA"
                     /locus_tag="KB913_002614"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6820910.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(4173..5804)
                     /locus_tag="KB913_002615"
     CDS             complement(4173..5804)
                     /locus_tag="KB913_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBB6820911.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            6108..6779
                     /locus_tag="KB913_002616"
     CDS             6108..6779
                     /locus_tag="KB913_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6820912.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(7504..7839)
                     /locus_tag="KB913_002617"
                     /pseudo
     CDS             complement(7504..7839)
                     /locus_tag="KB913_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2656 a         1577 c         1070 g         2789 t
ORIGIN      
        1 ccgcaccaat tatagaaagt aatgccctat ttttaactaa cccttttaaa gattttaaca
       61 atgaaacttt gtattgagat tggtcaattc ttactcgttc agtagttagt ttataacata
      121 ttaaataaca aataagtgca catatcgaaa atattcccgc aacaattgta aaagttgatc
      181 caccacgaac tatttgagcg cctgaatcat ctcttgtata aataaataat ggtgttaata
      241 caccaatgac caaacttgct aaagtagctc caacatttcg gaatgtcgat agcattgttc
      301 tttcttctgt aatagaagta atagctgatg ccattgatcc ataaggaata tttatagatg
      361 tgtaaaaaat actcccccat aatatatacg taacatacat gtatactacc ttaacgctca
      421 tagaagctga aatcatagaa gtttgataca ttaaaaaact tgctaaagcg actggaccac
      481 tcattcttaa aatccacggt ttaaacttac cctgcttagt tgctttcgat ctatcaacaa
      541 tacgccccat agttacatca gtaactgcat cgataaatct tgctactaaa aataatgttc
      601 caacggcagc tccgcttatc cccaatactt ttgtataaaa gatcattaaa aaagaactag
      661 caaaaatgaa agtaaaatcg tttccaaaat ctccaaacat atatcctatt ttgtctctta
      721 taccaaattt tctttccata caattctctc ccttctgttg ttaagcgttt tcattctgat
      781 gaaagtacgt actatactct gaagcgtaaa gagtcagtat ttatttttta catttcagag
      841 tattatttgt tttttctcct aataattctt tatctcataa aacttatcta tatatttact
      901 agctactcga cttacttctt caaaatcacc tttttcaaca gaagccaata aattcccacc
      961 tacaccaact gcaacaactc ctacttcaaa ccaatcttct aagttctcta tacttactcc
     1021 gccagtaggc attatattta cgtgtggtaa tggagcttga taggctttta caatggatgg
     1081 accaaaagca gaacctggga atagtttaat gatatctacg ccagcagtaa gtgcctcctt
     1141 tatctcagta attgtcatac aacctggtaa ataaggaatt tgatataaat tacaaatctc
     1201 agctgtttgt cgatcaaaag atggactaac gatatattct gccccagcca taattgcgat
     1261 acgagcagta aacgcatcta aaaccgtacc ggctccgatt attacatctt tttgatcagc
     1321 atatttttta gcaatttctt tgattatttc ttcagcatta ggaactgtaa aagttagttc
     1381 aatcccttta attccacccg caataattga atttattgct ttaatggcct catccttatt
     1441 tttcccacgt acaaccgcaa tgactccagc cgcttctaac ttacttaaaa tttctacttt
     1501 tttcatatct atctccttcc tttatggata catactttgt ctagctgtac taacttacaa
     1561 agaataaatt taagctttta tttcaagtat tattttctac ttccgatttc aaaaaaatta
     1621 aaataattat acgcattacg ataacaaata ttctccacta tctgactaag atacatttca
     1681 tcatctggaa ttcggcctgc tttaacccac tcgcttagta attgacataa tactcgacga
     1741 aaatactcat ggcgaggata gcttagaaaa cttcgagaat cagtcaacat acctgtaaaa
     1801 ttcgacaaca aactttgttg tgccatcgta gtcaactgtt gacgcattcc ttcagctgta
     1861 tcattgaacc accaagcaca tcccaattgg attttttgaa tcataccccc ttggaagctt
     1921 tgcattgctg ttgctagtgg aagccaatca gttggattta atgaatataa aattgttttt
     1981 ggtaagcacc cactcttttc agcggtatcg aacaatgcta caacattttg tgtcaaacta
     2041 gcttgatccc ccatcgaatc accaccgaca tctactccaa tttgttcctt taatatactt
     2101 gaattatttc ttaaagcatt taaatgcatt tgcatcgtcc aaccatatct tgtatactca
     2161 gacatcaaat gtaattgaat acctgtaaca aattgtgcaa tttctgataa atggaaatcc
     2221 gtttttcctg ctaaagcttt tattaacaga ttgtcgagta ttttttcatc tgctatttca
     2281 taaaaataag tattcaaacc gtgatctgct aatcgacagc caatttgatg aaaatgatcc
     2341 actcgttggc tcaatgcttg cttcaaccca ttaaagtctt tgattggtat agccgctgtt
     2401 tgactaagtt ttaaaatata gttcgaaaag cctgatgatt tgatactcca gaccttatct
     2461 ggacggaaag taggtaatac cttgaaagaa ttatcctgtt tagaaagctc agtatgatac
     2521 cacaagtcat ctgtaggatc atccgttgta cagatggctt tcacatccat catctccaac
     2581 aattctttcg ggcgatagga atccgtttga attttttcgt tagcacgtcg ccaaatttct
     2641 ggtgcattct tctcagaaat tgtcaaatca atatcaaagt aacgttgtaa ttccaaatga
     2701 gaccattcaa aaataggatt acctggcgcc ttctccactg tttttacaaa agctaaaaat
     2761 ttttcataat catcacctgg accactgatc aactcttctt ctataccatt agctcgcatc
     2821 aatcgccatt tataatgatc tccagctcct ttatcattta accatacctg agtcaaattc
     2881 ttgtattgct tattttctag caaatatgct gggtctaaat gacaatgata gtcgataatt
     2941 ggttggtgtt ttgcaaattt atgaaaaagt cttttagcta tttcattctc taataaaaag
     3001 ttcttatcta aaaacatatt taaacactcc tttccttccg ttagttttta gaagagaaaa
     3061 tttttcctct aaataaactc ccttatataa ttatttactc gccccctttt caagcgcttc
     3121 ccaaatacca tttaaataaa ctgcacctag agctcggtca tataatccat aaccaggtct
     3181 accggtttct ccccaaatca tccgaccatg atctggacga atatagccat taaatccatt
     3241 atcgtacatt gtttttaata tcttatacat atctagagaa ccatattctg atttatgcgg
     3301 cgcttcgtaa aaatcgagtc cattgtcact taaatatttg atattacgaa catgtgcaaa
     3361 aggaatccga tcccgttgac aaaattcaga tagaatttca tagacatcat tatctggtcg
     3421 ttctgcaata cttccagtac ataatgtaat accattagaa ggagaatcca ctacattaca
     3481 caaccaatct aaatcgtcac gatttttaac aatacgaggt aatccgaaaa tggaatatgg
     3541 tggatcatct gggtgaactg ccattttaat cccaacttct tcacatgtcg ggataattgc
     3601 tttgagaaaa tatgcaaagt tctctcgtaa tttctcttca tcaacttctt tataggcttc
     3661 taataattgc ttaatttgtg ataaccgatg aggttcccaa cccggcaatt caaaattatt
     3721 agtagaattt tctacttctc taataatttc ctccggatca gtagggatat tttttgaaat
     3781 ataggctaac gtagaagacc catcatctaa acgataatcc aaatccgatt ttacccaatc
     3841 aaatactggc ataaaattat aacagataac ctcaatccca aattctgcca aattgcgaat
     3901 cgtctgttta taattctcaa tgtattgatc tcgtgttggt aaaccaattt tgatatcatc
     3961 atgaacatta acactctcaa taactttcaa ggtaagtcca ttggcttcga cttcatcttt
     4021 taaagattta attcgttctc tcggccaaac ctctccggct ggtatatcca ttaatgttcc
     4081 aacaattcct ttcattgctg ggatctgacg aatttcttgt agtgagattt tttcttcatt
     4141 tgccccatac catctaaaag tcatttccat agttactttc ctccaacttc tgttatatat
     4201 ttattgattg ttttacgaac tgcttgagga cctactagca tttcgcaaaa gattttttca
     4261 gttttctttc ctaccccaac ttgatataaa tctaaaccaa agatttcttt attttctaaa
     4321 atttcctgta ccgcacaatg aatctttgaa ggatcttgtt cacctaattt caatactgat
     4381 aatttatcct gcaactctac caataacgga tcaggacttg gcacaaaatt ttccccttga
     4441 tcatcgactg ccagtaaata acgtaaccaa gcagcaatag cgataggaat aaatgttaga
     4501 ttttctgcat ttccgtcttt ttcgacatac tttttaattg tttcaccata gcgaatcgct
     4561 actttttgag aagtatctgt tgcaattcgt tgtggtgtat ctggaatata gggattaggc
     4621 aaacgtttat taattacttc atcaataaat tgttttggat caataatgcc tggattttca
     4681 actactggta aaccttctaa ataacctatt cctttgatta aaccaaccaa atcatcatcc
     4741 tgcatctctg ctgaaattga ttgatatcct agcagacaac ctgttactgc caaagcagta
     4801 tgaagtggat tcaagcttgt cgtaaccttc atgatgtctg ctttatcaac cgtctctcta
     4861 tctgtcataa tcacaccagc cttttccaat ttaggccggc catttggaaa actatcttca
     4921 ataactaaat aatgaactac ctcagtatta gtgaaagcag caatattggt atgttttttt
     4981 gtgtgaatga tatctaaatc ctcgagcccc atcatcaata gatcttcctt tacattctct
     5041 gaaggatttg gcgtaattcg atcaatcata ctccaaggaa aagtcacttt ttctttatcc
     5101 tttaaataag caataaattt ttcagaaaca tatccttctt tttgccaagc ttctgcaatc
     5161 gtaaaaatac tatcttgaaa acgttgacca ttctgtgaga aattatcagt agaaaccatc
     5221 gcaatcggca actctccagc attaaatctg ctatataaca aggatgttac aatactcatc
     5281 gtatgttgag gattgctagg tccagatttg atatcagctt tgactaccga aaagaattgc
     5341 cctttagaat cttttaaact gtaacctttt tcagtaatag taaacgttgt aaactgtaat
     5401 ttaggatctt caaaatattt aaccactctt tgatagtccg ctatattctt cggattgcaa
     5461 tataaactat cagccgttac tgccaaaagt ctttttttga gttcaccatc tccactcata
     5521 acaatttcca aaatgtcatt gttatagtca tgataagctt tttccactac ttcttcatca
     5581 aatgtttcac acacaactac tcctgtttct aattcatttt gatctgctaa gcattgagca
     5641 atttctgcat gaaatcctcg ataaagattt cctccaccaa aatgaagcca tactggatgt
     5701 tgctggcctt cttgcttaac ttctttgaca tcaaaacacg gcagtagaat ctgcatttca
     5761 ttgaattctt cgatagaatt ttgccaattt ttaatcgaaa ccataattaa cctcctcaaa
     5821 ctgatatgtt agttttgata cattttatat tttaaaaccc attgtaaccg ttgtcaatat
     5881 aaaaagggaa taaacttgct tttttctacc atatcagaat gattgtattt tttattcaga
     5941 aaaataaaat actccttctt tttggactga ttttatcgaa acttattttt tctttttttc
     6001 atgtattctt ttatttttat aactagtgta ttacttcaaa atttgatatt atatggcatg
     6061 aacagaatta aaatatcagt taaaataaaa gttaaggagc attgtgtatg acaattaaaa
     6121 ctagtctcca aaatcaagct taccaatcta ttcgccgaca aattatctat gctgacttag
     6181 aacctggaaa aaaagtatca gaaaaaaaat tagaagaaac actttctatt ggtcgtacac
     6241 caatacgtga agcactgatt caactccgac aacaaggtct tgttgataca attcctcaaa
     6301 gcggaaatta tatctcatta attgatttag attcggccaa aaatgctcga tttgtcagag
     6361 aacatttgga acgacaaatt atgttagagt gttgtgccaa aatgaataac caaaaaaaac
     6421 ggattttaga aactataatt tcagaacaag aaaaagctgt tagtcaaaaa aatgctcgta
     6481 gtttttttca taatgataat ttattccata aagcttgttt tgaaattgca gagcgagaag
     6541 aagtatggca atggttagaa aataacaata cacacttaga acgatttcga tggctacgag
     6601 taaaaacgga aggattaaag tgggaaaaaa ttatggaaca acattatcaa ctatttgagg
     6661 cattaacaaa acaagatcca gaagaagcta actttctaac atcgttgcat cttcatttaa
     6721 tgcttaatga gcaaaatatt gttttagcta ctcatccaaa atatttcaaa aatatataac
     6781 ttttaactct ttttaaatta aatggttgtt ctgatcagaa aaatatcgct tgttttctta
     6841 ttatgtaata tatttcataa actattctgc ataacaacta ttgtttgtac tttttacatt
     6901 ggataactaa ttatgactgc tgataacttt tgatattaaa ctagtatctc caatacaaat
     6961 aaaaaataga tatcttgttc atcaaaatta gttcgtggat acttaccttc atttacatca
     7021 ttcagcggtt tcccattttc ttttattcta ttatttcatt ttctaataga cttggcttca
     7081 tttcgcaata ctttttttca ataggcatca aattggtgtt gtttagatat ttagttgtag
     7141 ttttgtgaca tgataagtat gctccttttt ctcttttcca ctaatacaac gatcaaaggg
     7201 tgcttttttc aaaaaactag aaaaatcaaa ataagattcg tattttgatt ctatatatcc
     7261 tgtttcaact acatcttata tttcacaata gaataaatag ccttttgcat agctgcttaa
     7321 cttataagaa attgcaattt acttcttcaa agtgaaaacg aatatgagta aaataaaatt
     7381 attcttctta cagataatta aaaatagcgc gtaacaaaaa tcggcattca atcacataat
     7441 taggattgat gccgattact tatattctac gtatagtttt agtattctta ttttttatca
     7501 ccagtaacca attgagaaca gccctaaagc agaatagtct tttatctcaa aacgcttaat
     7561 ttcaggctta ggaatatgaa taatcttttg agtatattct ttctctttta atcttactga
     7621 agaaatacca ctgcctatct tttttacaaa tatttcattt ggtgtacaga ctaataaaac
     7681 aatatttgta atcaatcctt gcactaaaga attaaaagga agactattta aaacagggtg
     7741 tgcataacta taacatgtga agtagttatt ttgaacttta acttttaaaa actttaaaaa
     7801 taatcttatt tgttcttcta aacaatcatc tatactcata taatcactcc actaattaat
     7861 ctccccaaaa agacacagca ttaagagata taccaacaca acagtgcaaa taactctaca
     7921 tcttccttcg caaccttatt tcaataaacc ataaaaatta ttttttaata gaaactgaaa
     7981 attaaaacta gaaaaagtag ttttaccgaa tgtaagagca tcatcaccat caatatagaa
     8041 atacattctt ttccagttac atttaatttt taaacaaaat tctccccaaa aa
//
LOCUS       DADVXE010000098         7727 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.101, whole genome shotgun sequence.
ACCESSION   DADVXE010000098 DADVXE010000000
VERSION     DADVXE010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.101"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..107
                     /locus_tag="KB913_002618"
     CDS             <1..107
                     /locus_tag="KB913_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HBB6820913.1"
                     /translation="NESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(176..904)
                     /locus_tag="KB913_002619"
     CDS             complement(176..904)
                     /locus_tag="KB913_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6820914.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(917..2197)
                     /locus_tag="KB913_002620"
     CDS             complement(917..2197)
                     /locus_tag="KB913_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6820915.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(2338..2940)
                     /locus_tag="KB913_002621"
     CDS             complement(2338..2940)
                     /locus_tag="KB913_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBB6820916.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            3185..3391
                     /locus_tag="KB913_002622"
     CDS             3185..3391
                     /locus_tag="KB913_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820917.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            3703..4422
                     /locus_tag="KB913_002623"
     CDS             3703..4422
                     /locus_tag="KB913_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6820918.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4503..5186)
                     /locus_tag="KB913_002624"
     CDS             complement(4503..5186)
                     /locus_tag="KB913_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBB6820919.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            5405..7591
                     /locus_tag="KB913_002625"
     CDS             5405..7591
                     /locus_tag="KB913_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBB6820920.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         2774 a         1301 c         1457 g         2195 t
ORIGIN      
        1 gaaatgaaag tcaagaagta ttgctgaaag aaatggagaa ttggccaaca ttttatccag
       61 atacaatgga tggacgtgaa attgcacagg aaatgctttt gcactgatag gcaaaaaaga
      121 accgaagggt ttggatcggc tggtcattta gtcggtccaa actattcggt tctttttatg
      181 aaatcaattt ctttaatcca cggatagagg ctgggatggt ctcgccgttt gccaacgtga
      241 cttctctggt ttttttatta atcgaccgca cattttgtgt attgataaca taggatttat
      301 gacaacggat aaaattccga tgcattttct cgatttcttt gatcttctca tagaattgta
      361 attgggcatg agtcaaatgg acttccagtt tatgtggcgc tcctagcgaa gtagaaaaat
      421 attggatgtc tttgatcggt aaaaatttga tctcatcatt aaactctatt ttgaagatat
      481 ctttttggat ttgggacatt tgaaaatctt cgaaaatttt gctcaggata tgctcgacat
      541 tttcttttaa atcataaaga tcttctttga cgatataatc agtcggttcg atgttgcttt
      601 ttaagatttt catcgacatt tccgtatggg aagtcacata gattattttt cctaaaggat
      661 ctaattcacg gatcaattta ccgatcgcta caccatccat ttcactgtct tctagttcga
      721 tatctaaaaa gtaaatacca aaagaagaag ttctgatctt ggctgcattg agaagttctt
      781 ccggatcaga ggtagaaata tggacataac tgtctaagtt ttcaatcatg attctatttt
      841 tgatcaccgt tgataaaact tctaattgtt ttggatcgtc ttcacaaata taaatgggaa
      901 tcatatcatt actcctttat tttatttgta tataaatcgt ttgagaaaaa cgctggtttt
      961 caattgatgt ttcaaggaaa agataaggat tggtctttgt caattcatcc aagataaaca
     1021 agccaaggcc ttcgtttttt ggatttgttt ttgttgagaa ccctttttgt ttcaactggt
     1081 ttaacggtaa tgtatttgtt gttgtattga tcacacgaat catcacggaa tgattcttct
     1141 tgagtatggt caattcgatt tttttcttct ttgcagcact agctccttca atcgcattgt
     1201 ccaagataat accaagcata cgtacaaggt ttaccgtatg tttcgtatcc agttcgattg
     1261 gctcaggaaa atgaagctgg acgatcaacc ctttttcctg tgccatcatg agttttaatg
     1321 acagtaaact acggatctca ggaactttca tattatccaa catacttaga ttggccggaa
     1381 aaaggttcat catctggcgt gtaggtaata tcgtttgatc ataataagac cgtaatcctt
     1441 ctaagtcgcc ttctgaaata tagctgtgaa gagaaaaaag cagattttgg taatcatgtt
     1501 tgaattctct caagtcttga tagttttttt ctagatcttt gatataatcc tgttgcatcc
     1561 tgacttgttg ctctaataac tgatcagcta atttcttatt agagattttc caataataaa
     1621 ccaagatgat caggccaaca cacagatata gaatgaaaaa actcgtattc aaagctaaga
     1681 catcaggtgt ttcaccagaa aaacgggtat aaaaaataat gatatagtat gtaaataata
     1741 tcaatgtccc gatcgtaccg atcatacggc ggtccacagt gtgaaaccaa gtctctaacg
     1801 atttttttaa acaaaaagct aataaagcag ataaaaaagc ggataagaca atgtgaaaat
     1861 actgcaatga atctcctggt tcaataaccg aagatttcaa aacaaaaaaa tcgccgatgc
     1921 ttgttaagtg atctcctaaa agcgacgtca ataacccaaa aggaagcgcg taaaccaatt
     1981 gttgacgcga agtcgaaaag aagaaaaaag taagcatcag cattcctata gcaattagag
     2041 cagtaaaaat ccctaaaatc gaatagaccc atccaatcaa aatacaagaa atcagaatga
     2101 ctcccgcaaa cagatatttg tatcggatgt gatggtcaat caataagata caaattgtgt
     2161 aaatcaaata ttgcaacgct atggaccata aaaacataaa gtacagctcc cattgatttt
     2221 taccaaatta tagcacaatt ggcgtattat ttttttaatt tttcagggat tttgaattca
     2281 gaactcatac caaagcagca gccagataca aaaaagtcag ataagttagt taattgttta
     2341 atgattgttt ttttcatgaa agattcctcc aaaattcatc aagtagtttg taataggaag
     2401 caacgtagct atttctaaaa caatcccaag tagcaaatag gtagaaaagt aagaagctga
     2461 gaaaaataac gtaatgagag aaaaaattag aaacatgctg atcgccttct ttaataatgg
     2521 gggacgtttc tcgggttcaa tgggattgat tgctgtacct cttgatccat agcgaagcag
     2581 taacaaaaag cagctgatta acaaaaagac catcattggg aaggagatag tcaattgcag
     2641 atgtttcatc accaagggaa cgccccataa ataaagtagt gtccacagca gacaaacgaa
     2701 ttcagagtcg gaatgcaatc cataagcata tctgcggatg cagatataag aaagaaaggt
     2761 gattcctgtt tccgcccatg agcctgtcac cagagaaaag actagaacga ccgctagttt
     2821 tccaagatta ttcaataaaa cttctaagac aaattttact tggacataca ccatatcttc
     2881 ttccgatttg tctccgctga ataaggcttc taataatttg ttcacaactt tatctttcat
     2941 ctcatacgta cctccaccac aaattttatg ctaaaaaaaa taaaaaacgt cttttgtttc
     3001 ataaaaagtg gttttgacat caaaaccgtc atgatctcct aaaaaaatct tcgttttcca
     3061 agaaccttac caaaaaaagt gacagttttg atacgaaaag tactttttat gacaagtttg
     3121 tgctttttcg agtgatttat gttaaaaaat tactgacctt ataaaaggtg atggagggat
     3181 tcttatggaa aatgaacaat tgtttgaagt cggcgaaaca tatgcattta aatctgattt
     3241 atttgaatca ccaataaaag gaaaaataga aaaaatctat gaaaatagtg tgatgatacg
     3301 tgtcatgaaa tgcgcagtag aagacaatga taccgctcat aatctgcact ggcagttagt
     3361 tgtacgcaaa tcaagtacaa tagaagaata aaaacagata aaatgttgag agcataaaga
     3421 ggttgtgagt ctcccgttta gctctgagtt acaaggaata atgttaaaaa acagcttttc
     3481 atgttttatg aatattgcct tgtgaccgag gtgttggcag gagaatactg tttatttgaa
     3541 aaaagggctg cgacaagact tttgtcacag cctttatttt catgaatagg agttactttt
     3601 ggctactttt agagaagtag cttttaagga gcagataaag tcaaggcttt tatttctata
     3661 aatgaagtag taaaatgaag aacagatttt attacaggaa ggatgccgat aattgtgatc
     3721 attgttgcag gaacgatcgg tgcagggaaa agcacactaa ctgaaatgct tgcccaagat
     3781 ttagaaacaa aaccttttta tgagaacgtg gaagataatg aagtattgcc gctattttat
     3841 tctaatccag aaaagtatac ttttttatta cagattttct ttttgaacaa acgctttttg
     3901 gcaatcaaag atgctttcag ccatgatgac aacgtactag accgctccat ctacgaagat
     3961 agtatgctgt ttcatttgaa tgcagattta gggcgtgttt ctgaagtaga agtaaagcag
     4021 tatgaaggtc ttttagaaac gatgctgaag gagttagaag aaatttcgcc acaaaagaaa
     4081 ccagatctac tggtttatat tcgtgtatcc tttgaaacta tgttagcgag aatcaaaaaa
     4141 agaggccggg aatatgaaca gctagaacaa gatcctgaac tctattccta ctataaagaa
     4201 ctcaatcgac gatacgaaga gtggtatgaa cagtttgata tatgtcccaa aatagtgatc
     4261 gatggggaca aatatgattt cgtagccgat ccggcatgtg gagaacaaat cgtacaagaa
     4321 atcaagatgc gggcaaagaa aatgacagaa gaggcagatg cccagtcgat ccgctacact
     4381 acaaataacc cgaaagcaaa gggaatcttt acaactaaat aatataaaaa ctaagcaaat
     4441 tgctcactcg cagatatttc tctgtgagca gcatcttgct tagttttttt gattcattga
     4501 gatcaaatag tgaaccgatt cgtatgataa aattgccata aatgaaatgt ctgagtgagg
     4561 gccatgatca aaaataaaat ggaaacgatc aaaatcgaat gggcgccaaa cagatgatga
     4621 cagaaaacaa ggacaatagc tcctgcgata aaggcaagaa cgacacttag atagtggaaa
     4681 aatcgatcaa aatctgcttt ttctttagaa atacaataat catataagtt cgttgctacc
     4741 ccttttaaat ttccagttgt aaataaatta gtgtaggcac gcccgttgat tttatcaaaa
     4801 gctacccact ggatcgatgc agtaaaagca atcaaaatcg ttactaatgc gggatgctca
     4861 tggacgggtg tcaaactaac aaagaaaaaa atcactgctt cataatatag aacaaacaag
     4921 cgccagaaat gtttttcttt ttttctaaaa taatcaatta gatactttgt tagaagaatc
     4981 cctaagaaaa agaaaagggt agacaatact tttttaccaa cacttagcca ttctccgtca
     5041 aatgcttgga tgatcgatag aatgatattg ccagtttgag cagaggcaaa agcaccatat
     5101 tggatataag tataactgtc catggctcct ccgataaatg tcagcaaaag tcctattgta
     5161 cgcccctcgt gaaaggaagt ctgcattttt ttcatcacct tttatgaata tttttgtctt
     5221 ccttatctta gcataaacga ttgaaaaaaa aggaaaaatt ttcagaaaac taaaatcata
     5281 tcgcttccca ttttcatttt tagaaaggtc tgttagtata aagaaaaaat agacaacgaa
     5341 actttaaata accaacttga aataaacaaa ttcaaagaag aaagatggga aggaaatcaa
     5401 tcagttgaat gaaaaagaaa ttctccgatt acaaaaagaa ttgaaacgct gggagaacaa
     5461 gtataaaaag cttcaacaag tctttcggct acaagaagaa atcattgcta cctatgaagc
     5521 ggcttatggc gaagcacccg gacttattga ggaagaagta caagtaaaag aaagtgaagg
     5581 aaacagctct ttctttaaaa tgatggagaa acgttcctat aatcgcttca atcaagaaca
     5641 aaaagcagct atcacatatg atatgaagaa acatcttcga atcatagcag gagctgggag
     5701 cggcaaaacg caaacaatct gtgcaaaagc tgtttatctg atgacgcaaa aacaagtaga
     5761 cgaagaacgc atactaatga tcacttttac aaggaacgct gcaaatgaac taaaaaaacg
     5821 agtagataat ttcagccaga gaaaaaccgc tgtccatatc ggaacattcc atagtatctt
     5881 ttttaggata tacaatgaaa tttgtcgaaa atttcctgaa gtagcaatgc aaggaataca
     5941 aggagacttt tcaaaggata ctgcacaaaa agtgaatgct gttttgcaac agctgatacg
     6001 taaatataat ctttatatat ttgatcaata tggagaaaaa acgattgctt ctcggttaga
     6061 ctattggcag aatatgaacc tttcagtaga agaaatggtt cagttagtta aagaaaaata
     6121 tgattccatt gataagaatg cacgacagcc gatatcagaa cgactgtatg gattgctcac
     6181 ggaactccaa gaacaaaaaa gaagccagca attgctagag ttcaatgatg tactccaaaa
     6241 tctgaaaagc gctttggaga atgaggagat ccagcattat atcggccaaa aatatgatta
     6301 tctattcatt gatgaatttc aagatactaa tccacttcaa tgggaaatcg tgaaacggat
     6361 gacaaaggaa aacaggatca agttgattgt tgttggagat gatgatcaga gtatctatgg
     6421 attcagagga tcagagccag catacatcaa gaactttgaa aaagaatatc ctaccaaaac
     6481 tcttttctta ttaactaatt atcgttctcg ggcagctatt gtccaaggag caaatagatt
     6541 gatcagctat aataaaaatg atcggatacc aaaggcgatg attccagcac aaaaagaagc
     6601 aggtgttatg gaagcctatt tgttttctga tactaaagca gaaagtcagt ggctaatcaa
     6661 acaaattcag acatttattc aaaaaaatgg gaaatataag gaatcaatca tattataccg
     6721 atcagcttca caaacgcagc agcttgtcca atctctgctg aaaacgaata ttccttttgt
     6781 actggaagca gatagtccat atgaaggtat ctttggtatc aagtctttcc aacatttcta
     6841 tcaaaaaatt gttcattggc aaacagcact gaatctgcaa aagaaaaatc aggcctacca
     6901 gcaattgctc cggcagctga tggcagactg ctacctgaaa aaaagtgaat gcgatcaata
     6961 cttttctcct aaatatcaaa atatagccgt tgcagattat attttgtcga taagccccaa
     7021 tttaaaatcg aaatctgcag aaatccgaga gtttgaggaa gcgttgcgta aaacagacca
     7081 gcatcaagaa atctattcgc ttgttcaaag ctatcttcat ctgccacgta tagctaagga
     7141 aatcgaccag agtgatcaag aatggatacg agaagaagta aagcagcatg ctactttcag
     7201 aagactccaa gccttatcgc aagaaaccca agcgacagct aaagaattaa aaacccgctt
     7261 gattgcttac agacaaggaa aacttgatgc actatgtatc cagagcattc acaaaagtaa
     7321 aggtcttagt taccgaaatg tctttttgat tggttgtaac gaaggaagtt tgccttataa
     7381 cggagcgaca gaaaagaaag taatcgactt taatgaaata aaagcagaac cagtaacgac
     7441 gatagaagaa gaacgaagac tattttatgt tgcgatgact agagcaagaa atcgtctgta
     7501 tctatgtgta cctcaaatga aaaattcaag aaaattgaaa gtatcgagat ttatcaaaga
     7561 aaccgggagt cgtgtgaaaa aaggaaagtg atagaagaga gggtgtgaca gaagtggtca
     7621 gtttcaagaa agaagaagga atgtacgaaa attgcttctc aaatttttgt gaaatttcag
     7681 cttattttcg aagaagctat ttctggaaca cagtttattc ggaaaag
//
LOCUS       DADVXE010000099         7698 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.102, whole genome shotgun sequence.
ACCESSION   DADVXE010000099 DADVXE010000000
VERSION     DADVXE010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7698
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.102"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            17..2344
                     /locus_tag="KB913_002626"
     CDS             17..2344
                     /locus_tag="KB913_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6820921.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            2470..2799
                     /locus_tag="KB913_002627"
     CDS             2470..2799
                     /locus_tag="KB913_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBB6820922.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            2839..3843
                     /locus_tag="KB913_002628"
     CDS             2839..3843
                     /locus_tag="KB913_002628"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBB6820923.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            3840..4286
                     /locus_tag="KB913_002629"
     CDS             3840..4286
                     /locus_tag="KB913_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBB6820924.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            4436..5251
                     /locus_tag="KB913_002630"
     CDS             4436..5251
                     /locus_tag="KB913_002630"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6820925.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            5457..6629
                     /locus_tag="KB913_002631"
     CDS             5457..6629
                     /locus_tag="KB913_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6820926.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(6839..7324)
                     /locus_tag="KB913_002632"
     CDS             complement(6839..7324)
                     /locus_tag="KB913_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820927.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQEAI
                     AQQQAEQARQQSAAEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATL
                     S"
     gene            complement(7321..7515)
                     /locus_tag="KB913_002633"
     CDS             complement(7321..7515)
                     /locus_tag="KB913_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820928.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
BASE COUNT         2578 a         1456 c         1536 g         2128 t
ORIGIN      
        1 tttattgaga ggagggatga aaatgattaa gaaaactcaa aataaaatcc aacgtatatg
       61 tcaaaaacat tttgtttcta gactcaaagc tgtatctaaa agaaaatact tacatcccat
      121 tatgatttcg atcatcttga tttttacttt cttagggagc ttatcaagta tttatgtaaa
      181 cgtttataca gaaacgtcaa attttgctaa ccaaacgaca gaggagacaa atagtccacc
      241 ctattctgaa atacagtcca tagaaagcac caatcagtct agcaacaacg agacaacctc
      301 aaccacatcc tcgactcaac tgattgatcc gacagaaaaa gaaatcacag cagcaaaagc
      361 agcaggggag aaagcttatt cagaaacagg tagaagccag acatttagta ctgttgcggc
      421 cactgcgaat ttcaacggac ataccatacc agatggatat acagtgatat atgccaaaga
      481 tggagtcatt gttgcggtta acggatcgat gagtgcggat aaaactgcgt tacaaggcgt
      541 aaccaaagca atcgctttta ttgataaccg tccagatatc cataatctgt ttattggctc
      601 cacagtaaat ggtactacta tcacattccc aaaaagtatc tatatggggg tggctaccgc
      661 tggaaatacg atcgattcag ttacacccaa tgcggataaa agttattctt ttacaccctc
      721 aacatgggga gggcttcctg ccggaggagg tatgagtact ttttcaatcg gtatacagtt
      781 agcaaatgat attccattca cggggtactc gatcaaaaat gggcagatcg ttgatggtaa
      841 gggaaatgtt tcaaattttc caacctatca agcagcaacg gttcaggtca atgcgaatcg
      901 gacaggaact ttttcttata cagtcaatgg tggagcagca aaaatcggaa cgtacgggac
      961 tacattatct ggaatccatg tgggtgacaa agtggttatc actccaacag cagtaacggg
     1021 ctattctttt gcacaaacaa acggttcttt cacagcccta gaaagtaacg tcgatacggt
     1081 gacctataca ggcaaacaaa caccaatcac tattaagtat caagactatt ttggacagat
     1141 gattgctcct tctaaaataa tgaatcttac ttacggaagt gctgcacaag acctgacgac
     1201 taatacgcct actatcaacg gatatacctt tacagctgtt tcagcgatag aaacaaagaa
     1261 ccaatcagca atgagtgttt tagctagttt agatacaaat ggaaatgtaa tcgtaaagga
     1321 cgcaaatgga aaacagattt ctgaagtcat cctatattat aagacaaatg caacagtatc
     1381 aatcaatgca aatggcagta agtactatga tggtctttct gttgtaccga tcgttaaata
     1441 tgcctttaat gataaaacag aatcaacatc ccttttaaac aatgatctca gtattgatca
     1501 aatcacatgg aatccaactg atttcaaagc gatgaatgaa aagggagttg aagtaactgc
     1561 gcctactgaa attggaacct atacgtcttg gcaattgaca aaaagcggac tagctaaact
     1621 agctgccaga acaaactatt tatttactat cgtgcagaca tctgatgtct atacgattaa
     1681 gcaaatcagc ggtgcggtag agctcagtgg cagtaagaca tatgatggaa aagcaggtgt
     1741 cccgtcaatc catgtcaagc tagcagaggg tgtcactagt tcgcttactc cagtacaagt
     1801 ggcacttagc agtatggatt acacagcaga tgcacaatca gcaaaaaata tggttaatgc
     1861 tggcagctat acaattaaac taacgaatag cggaatagac aaagtcaaag cagcaaatcc
     1921 caagttgtca tttactgata tagccaacac atcaggaact tataccatct ataaagctaa
     1981 cgcagtgatt actgtcgatg acgctgcctt taattatgat gcccaaagtc actcgatttc
     2041 ggttggaaat ctccacgtta ccggtgttgt cttaggcgaa tcattggatt ataccctaac
     2101 agttaacagc cggacagata ttggatcaca aatagtaacg attagtttag gcgaaggaag
     2161 tgtaaacaat aattatacga ttatcgcaac agataccgct aagttgacga tcaatccgac
     2221 tctcttgctt ccttcgacag gtgggatagg tctactgccc tttgtctttt taggactgat
     2281 ctttattttt tctggcttct tttattttat ccatcgtaag aaaaaagcag gtgaacagcg
     2341 atgaaaaaaa caaaaaatgt acgtgtggat atatttgctg ttctcttttt tatcctactg
     2401 gtctttttta taggttctcc gactgtgtca gctagagaat cacctattac atttactttg
     2461 cataatcgaa tgttcgaaag cgataagatg ccaagtatca gtcaaaacga cggaataaat
     2521 atcccggata actttcaagg agtaaaaggg ttgaacggcg ttactttcgc tatatatgat
     2581 gtctcggatg aattttacaa gctgcggtca gaaggaagta gtgtggaaga cgcacaaaga
     2641 aaactagcac aaaaaagtga tagtgaaaaa atactggcag aaaatgtgac aaaaacagta
     2701 gacgaggaag agggcattgc ttcttttagt gcatcggaca aagatgagca aggtcgtgac
     2761 gctgtttacc gatttacgga aataaagact tcagattaag taaaagaaaa atcagcacca
     2821 tttgtcgttg tgcttcctgt gacagattca tctaatcata aattgacgac catccacttg
     2881 tatccaaaga gcgaacaaaa aatacctgct gcactcacat taacaaaaac agtagagaat
     2941 aagcagacag attttgcaga tggggataaa gtcccttatc tcatcaccgt aacaattcct
     3001 gagaacatca acgagatagg aacctatacg atcaaagata cagctgatcc tcagttatgg
     3061 ctagaaccag aaacgatcga ttttttgatt ggtggagaca agattcatac atttcacaca
     3121 caaaaaataa aacatggttt tgtcttatca gattctggaa aagatcttag ttcgtttgct
     3181 ggaaaaaaat taacgatccg ttaccaaatg acattgaaag aaaacagtga aaaaacgaca
     3241 tttgataacg atgtacgttt gacgactgac aatcaaacag tagaaacaca tcttgccatc
     3301 caaacaggag gcaaacaatt tgtcaaagtg gatcggcaaa cgaaacaaaa actagcagat
     3361 gctcaatttc tagtcaaaaa aaatgaccaa tacttagcgc aagaaaacgg gataaatcat
     3421 tgggtagcca aagatgattc aagagcaacg atttttactt ccagtaaaga tggaacattt
     3481 tctgtccatg gattgtcttt tggaagttac gaactagtgg agattaaacc gcctaaagga
     3541 tatatattga gtcaatcaac cattctcttt gaagttgaaa aaggcagtta tgatccgctt
     3601 catcctatac cattggaaat catcaacgaa ccaaaagcaa atccgacgaa taatggaaaa
     3661 acgccagttc agatgcagac aaatggtcca tcaaatgaaa aaaatggagg aagctttcca
     3721 aaaacaagcg aagagatgct tggaggtttc tcaattttag ggttattgct agtcctttca
     3781 acagggacag cttggtttta taaaaaacaa caaaaaggaa acaataggag ggaaataaaa
     3841 tgaaaaacat caaaacaaaa atatggacgt ttttaggaac tgctatcatg ctgcttcctt
     3901 tcgttctcgg cctaggaact gcagaggttt ctgcagccgt atcacctaca ccagaaaatg
     3961 ttacggttaa tttgcataaa ttgaaattca cttcagcacc agaaaatcaa ataaacaacg
     4021 gaacggaatt gacatttccg aatagcgaac cgttgaacgg cgttgaattc aacgtatatg
     4081 acatcactgc tacgtactat ccaagtaaag acacagcagt tccagcagac gctacaccct
     4141 tcgcaagtgt aacgacttct ggtgaaggat tagctaacct gactcttcca ggtaaatctg
     4201 atgggaaaga tgctgtatac gtctttgtag aaacaccaaa gcccggtgtc gaaacgtcgc
     4261 caaatatcgt gttaagctta ccctagaccc tgacaaacct ttagacacga ttcacctata
     4321 tgctaaaaat gtcatcaaag aaagcaatat caaaatccag aaagctggga acttttcagg
     4381 ggtagataag ttagcagggg cgcaattcca gatcaaaaat tcagagaatc aattcgtgac
     4441 cggttttgat gaaaacactg gtgtcgctct ctatgatcct gctgagtcag cgttgacatt
     4501 cacaactgat actgaaggat ccatcagtgt caatggatta atagacggca attatacttt
     4561 agttgaaaca aaagcaccag atggttatca attaaccaat ccacaaaaag aaactacttt
     4621 tatagtaaaa aacggaaaat tgcaacaaac aaccggtatc atccatggcg cagatgaagc
     4681 caatcttggg aatccaaacg gtgtagtcaa tcgggaaaat acaactacgg ataacacgat
     4741 tactgtagaa aatgtccaaa actacggtga tttccacttc atcaaacaag atgtgaacac
     4801 gcaagaaaaa ttagccgatg cagaattttc tattctaaga gcaaaagatc caactgttaa
     4861 attaatgaaa aaaatagcaa accttgcctc aggagaatac ccatatgctt ggtcagatga
     4921 agtcacaggt tctgactggg aagaagtgaa attgatttct gattcagaag ggaaattttc
     4981 aatcgaaggg ctgaaacaag gggcatactg ccttcaagaa acaaaagcac cagaaggcta
     5041 cgcattacct aagaatgaag ctgcgtacac tgaatttaca gtagatgatg atccaacaac
     5101 ttctgatgaa acaacgatcg ataaccaacc taaaggaatc ttgccttcaa ctggtggtat
     5161 ggggatcatc gtattcatct tggtaggtac tgctttagtt ggaggagcag tgatctattt
     5221 caaaaaacgc catcaagaaa cagaagctta aactattgga aacaaaaatc atacgataaa
     5281 taaacgatag tgattcaaat ggggagaaag gttgtgacaa gtggtcggtc tcttggtatt
     5341 cgctcaacaa acggcaaaat aggaggaact attttgccgt ttgcttcgct aatactcagg
     5401 tcaaggcgct gatttcacaa cctcttcata tacatattag aaaataggtg gacatgatga
     5461 ataaaagcag aataagaata ctggacatct tcatggcaat cattttagtc gttgggatcg
     5521 ggatcttttc ttatcctttt gtagaagatt cactgaatga ttttcttgcc cagcaaatga
     5581 tcatccatta tcaaaagcaa gcatcgaata agaattcaga ggaaataaaa aaacagcagg
     5641 aaaaaatgac aaagaaaaac caacagttgg cagagcaaaa cgtatcacca gggataggca
     5701 gtttcaacca agcagttgat gcaaaagcat taaaagattt acctagtaat gcctttttta
     5761 tggaacatat gcttggagtc atcgaaatcc caaaaatcaa tgtcagctta cctatattcg
     5821 atcagacaac ggaaatattt ttgcaaaaag gaacgtcatt attggaagaa agttcttatc
     5881 cgactggcgg gaaaaacacc catgccgttc tttctgggca tcgtggactc ccagaagcaa
     5941 aattatttac agatttgcct aagttgaaaa aaggagacca gtttttcatc cagatcaatg
     6001 gaaagacatt ggcgtatcaa gtagaaaaaa tccaagtggt cttacctgat gaagtagatt
     6061 ctttgggtat ccaaaaaggc agagatctcg tgactttgct tacctgtact ccttatatgg
     6121 tcaatacaca tcgactgctt gtgacggggc atcgtattcc ttatcaagca aaagaggcaa
     6181 aaaaagcgat ccaaggaatt gatcaatgga aaaaatggaa attttttatt tggtttatcg
     6241 gtatactact tggatcaatc ggcttagttt ggctactcat cgcttattta gattctttgg
     6301 ccatcgctaa gcgaaactat cctttatctt tttatgtaaa gaacacaaac ggacgaccaa
     6361 tcgaaggaat ggtcttttct gtaaaaacgc tcaacggcaa acactatatt actagagaaa
     6421 aagttccatt tgtgaaagct tctgatgaat acggactagt gagattttct gatttaaaag
     6481 gcaggaacta tcgcttgcaa catgaggagc tcctgcttaa aatccatgta aaacataaac
     6541 attcgaaaca gttttcaatg aaattgaaaa aaggaagata taaactgcga aaagaaaaag
     6601 aggtgtacta tttgattgag aaagaatgaa tgaagatgtc caaaaaagca gagggaacag
     6661 actaaatgaa aaaagagaga agctgacgaa atggacgtgt aaactgttat ttttggttta
     6721 ctatctggaa cgccatcttc tattttttta tgtttcagaa gaattttatt attatagtat
     6781 aacttttgaa ttagtttcca taacatttgg agcaaggggt taaaccacga gcttgagctt
     6841 agcttaaagt ggcaggggta tacgtaccat ttccacattt atgtgtatgg tattttgaac
     6901 cggtcggtgt gacatagaca gtttgttcat tattttgctc aggagctgcg gcttgtgcct
     6961 gctgagaggc ctgttcagct gctgattgct gtcgcgcctg ttctgcttgt tgctgtgcga
     7021 ttgcttcttg cctcgcctgt tctgcttgtt gctgtgcgat tgcttcttgc ctcgcctgtt
     7081 ctgcttgttg ctgtgcgatt gcttcttgtt gcgcttgttc tgcttgttgt cgtgcaattt
     7141 cttcttgctt tttccgttct tcttctgctt cttttgcttt gattgtggaa tcaattgcag
     7201 caagacggct tgtcaactct tgtttgtttt caggtagcgc ttggatagct gctgaagcag
     7261 ttgcatagtt ttcttttgta ggatttgctt cagcttgtga caaagcagat tccgcttctg
     7321 tcactttttt tctagtgcag ctttttccgc tttttgtttc tcttcttttt tcttttcaat
     7381 ttgttcttgt tctttcgatg aatctgccgt actttcggag atcgtggtac tgctgctgga
     7441 agcctgatct gaacttgtgc tttgagtagt agacgtagta gcaccacacc cactcaacaa
     7501 acttcctgcg accaaaaaca atgcaactaa ttttttcgct aaatttcctc cttaagtaaa
     7561 aaacaaccgt tttcaataaa tgtccttttc aattgtttac ttacttgtta taataattgt
     7621 gttatgaata gtgattgagg aaacttaatc taatcccgtg ttgatacacg ggattttttg
     7681 ctatagttct gttattaa
//
LOCUS       DADVXE010000100         7391 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.103, whole genome shotgun sequence.
ACCESSION   DADVXE010000100 DADVXE010000000
VERSION     DADVXE010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.103"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(204..1652)
                     /gene="cls"
                     /locus_tag="KB913_002634"
     CDS             complement(204..1652)
                     /gene="cls"
                     /locus_tag="KB913_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBB6820929.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1804..2697)
                     /locus_tag="KB913_002635"
     CDS             complement(1804..2697)
                     /locus_tag="KB913_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6820930.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="KB913_002636"
     CDS             complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="KB913_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBB6820931.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3472..4573)
                     /gene="prfB"
                     /locus_tag="KB913_002637"
     CDS             complement(join(3472..4500,4502..4573))
                     /gene="prfB"
                     /locus_tag="KB913_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBB6820932.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4699..7233)
                     /gene="secA"
                     /locus_tag="KB913_002638"
     CDS             complement(4699..7233)
                     /gene="secA"
                     /locus_tag="KB913_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBB6820933.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
BASE COUNT         1976 a         1639 c         1289 g         2487 t
ORIGIN      
        1 gctatactgg ctttgaaatg tgtctctttt aatagcatat attagcttat ttcttgcttt
       61 ccccaaaaaa caagagatac cccaaagtta atttcgctca tgcgagacgc tttctccatt
      121 tctgacgtac tctcagaaat ggccccgtta aaaaaggaca cgagatctcc atctgttgat
      181 ggttctcatg tcctttttat gttttaaagg agcggcgaaa tcaatcttgc taatccttct
      241 ttcatcttga tgattattcc tcggttttca tacatttctt ttgtgagatg cgtagaaatt
      301 ttcgagtctt caaaaaaagc ttttcttaca cgtgaagcca ttcgttcatc ataaaccagt
      361 gtattgacct caaagtccaa gcgaaatgaa cgaacatcga tatttgctga gccaactgaa
      421 acaatgccac catcgataat catcgtcttt gcatgaataa atccattctc atatgtttcg
      481 atccttgctc catactcgat cagctctgca gcgaaagaat acgttgccca gtaaacgaga
      541 agatgatctg gtttgttagg tatttggata tgaactttta cgcctgaaag aagagccaac
      601 ttcagtgctt catgaatcga tccatccggt atgtaataag gcgtttggat caatatctcc
      661 cgtttggcta acgaaatcat tttcaaataa gtcattttga tttgttcatg ttcggtatct
      721 ggtccgcttg tcacgatttg aacagctata tcaccagtag tgtgaatgga cggaaaaaat
      781 ttgggagaat agcctacttc ttttgtatgc tgagaattcc agtccatcaa aaaacggttt
      841 tgcaaggtat acaccgcttc tccgtaaata cgcaaatgat tgtctcgcca ataaccaaat
      901 ttctttacca atcctagata ttcatttcca acattgaacc cacctgtata tccgatttcc
      961 ccatcaataa ctacgatttt acgatgattg cgataattga tccgaggatt aatatacgga
     1021 acaaatagag gaaagaaaaa tgcgacttct ccgcctgctt ttttcaaatt ctgaaaaaag
     1081 ctggaagaaa cttgtgtgga accccatgca tcaagaagga ctctgacttt tacccctcgt
     1141 cttgccgcct ctgtcaatgc atctcgaact tcttcaccta atgcatcact gcgataaata
     1201 taatactgga agtggatatg gtcttctgcc tgcttgatat cttcaatcag cgcatcgaat
     1261 ttttcacgac catctgtaaa taaagtgatt tcatttttag tcgtatagag cgtactttca
     1321 aataccgtga gcatatagat caattgtttc acatctactt gtccagtagg cggatgagga
     1381 taaagccctc gcatcaatgc ctgtttgtct tcttcaattt ccaggttctt accgattttc
     1441 ccttggatct tcaaatcaaa gattttctct ttggaaatcc ctcttcctaa aaaaatatat
     1501 aaaataaatc ctacaactgg aatgaacatc aaaacgagca gccatgccca tgtttgagca
     1561 gtttcctttc tttctcgaaa aacgatgata aaggaaagca aaatattcat aatcaaaagg
     1621 atcgtaaaaa aattgtcaac gataattttc acggcttcac ctcttcttct accaacttaa
     1681 gaatacccaa gttgtttttt aaagtaaagg gaaaaaagcc gcttccttct attctcctag
     1741 ccaataaaaa aagaaagctg gaacgaaact gtccaacttt ctcattttat ttatattgtg
     1801 gtattagaat ttcaagaaac gtctcataga aatgatcgag ccaagtgaac caatgatcac
     1861 accaatgccg accattaaaa gattgatttt ccaaacgata ttttgtggat gaatcaatga
     1921 ataatgggaa cgtaataatg atggattgat caattggaaa aaccatgcat aaccaaatgt
     1981 gatgatcaaa attggaagaa ttgcaccgat cagaccgatc cagccacctt caaggaaaaa
     2041 cggccagcga atatatccat tttttgcacc gactaaacgc atgatttgaa tttcacgctg
     2101 tctagacaaa atcgtgatcc gaatcgtgtt cgaaatgaga aacatcgcta cgaacagcag
     2161 caatgccgct gcaactaatc cccatgtccg aactgcacca gcgatttgga aaatccgatc
     2221 tgaggaagct ccaccgtaat cagaacgaga aacattcttc aaatctgctg cttcttctgc
     2281 tacttgtttt gtataagaag gatcagtagc acttactaca tacacatcat ataacgggtt
     2341 attgtcacct tcaaacaatt tccaggaatc acccatttcg ttttggattt ttttcaattc
     2401 ctgttctttg cttgaaaatt caactttttt aacatgatct aagtcattca attctttttc
     2461 tagctttttc atctcttcgt cttttgtacc gatatctacg aatacagata catcaacgtt
     2521 tccttctata tcctgagcta atttagttgc attcatgata actgccatga atacaccgac
     2581 taaagtcaac gtgatcgtta ccgcactgac tgaagcaact gtcatccagc cgttacgttt
     2641 caaactcttg atactttcta ataaatggcg gaaaaaggtt ctaatcatcg tatccatatt
     2701 ccccttccgc ttgatctcga ataatgcggc cgttttcgat agcaattact cggtgccgaa
     2761 tcgtatttac gatcgtactg ttatgtgtag ccatcacgac agtagttcct tgggcattga
     2821 tccgatctaa taatttcatg atttcccatg agttttctgg atccagattt cctgtcggtt
     2881 catccgcgat aagtacttta ggcgtattca cgattgcccg agcaatagag acacgttgct
     2941 gttccccacc ggataattcg ctaggaaaga ctcgaacttt gtgtttcaaa ccaacaaggt
     3001 ccagcacttc cattactcgt tttttgatat ctcgaggttt tctgccgata acttgcatag
     3061 cgtacgcaac attttcatat actgtttttc ttggtaataa tttatagtct tggaacacca
     3121 cgccgatttc tctgcgtaga taaggaactt cgcggttttt gattgctatt agatcatgac
     3181 ctgcgacgtt caaagttcct tttgaagctt tttcttctcg atacatcaat ttgatgaatg
     3241 tagatttacc ggctccagac ggaccaacca catagacaaa ctctccttgt tcgatgacaa
     3301 tcgagagatt gcggatagcg gtcgtaccat ttgagtactt cttcattaca tccttcattt
     3361 caatcatggc gttctctcca tatctttttc agtctttagc tattatagca tggcaatgtt
     3421 tcaacatgct tgcaaaatct tacaatttta tttcaattta acaatgggtt cttattgtag
     3481 atgcattttt aaatagccgt caataaataa atcaaggtca ccgtccataa ctgcttggac
     3541 atttcctgtc tctacgtttg tccgatggtc ttttaccata gaatagggat ggaaaacata
     3601 agaacggatc tgtgaacccc agccgatttc tttttgttct cctcgaagtg cagctgcttc
     3661 ttgttctttc ttttccactt ctaattgata aagcttagct tttaacatcc ccatcgcttg
     3721 ctcacggttt ttcaattgtg agcgttgtgc ctgactagct actactgttc ctgtaggcaa
     3781 gtgagtgatc cgtacagcag attctgtttt attgatgtgc tgaccacctg caccacttgc
     3841 tcggtacgta tcgattttca aatcatctgg attgatttct atatcgatcg tttcatcaag
     3901 ctctggcatc acatctaccg aacaaaaaga agtatgacgt cgtttcgctg agtcaaaagg
     3961 cgaaatccgt acaaggcgat gaacaccttt ttctgatttt agataaccaa aagcgttatg
     4021 tcctttaatc agcagggtca cactcttgat ccctgcttca tcacctgctt gataatctag
     4081 tgtttctact tgatagccat gctgctctgc ccaacgtgta tacatacgta aaagcatgct
     4141 gccccagtct tgggactccg ttccgccagc ccctggatgc aattcgacga tcgcattgtt
     4201 tcgatcataa ggtccgtcta acagcataga taattcatac gtcttcattt tttcatctaa
     4261 tgcattgata cgtgtttctg cttcttcttg cattgctgca tcaggttctt cttgcagcat
     4321 ctccaccatc aattcgattt cttctagttc ttcggcaaga gaatggaatt ggtcataggt
     4381 ttctttatta gcgttatttt cgctgatcac tttttgtgcg gcttcgctgt catcccaaaa
     4441 accaggttca gccatttttg cttctgcttc cgcgatgtct tcttccagct gatctaagtc
     4501 aaagagacct cctgaaactt gtgacctttt cctgcatttc tgtcaggaga tttcgaattt
     4561 cggatatttc catgtttttt ccttctttca ctatactttt ttcattatat ctagtctaac
     4621 agaatcagca aataacagaa agaaggtgag acgaattctt aaaaaaagaa tttgtctcac
     4681 caatcctgct gtcagaaatt agtttgcatt ttttccatga cagttcttat attttttccc
     4741 gcttccacaa ggacaaggat catttcttcc gaccttattc acatggattg gctgtttttt
     4801 cgcgctagta ttactatttt ctttggcatc tccgtcttct gagtgagaag ctgttccttg
     4861 agaaacctgt tcacgctgta cgttttgacg gatctcagct ttcataaaga ttcgagtgac
     4921 ttcatactcg atggcgccta ccatatcttc aaacatctta tagccttctg tttgatattc
     4981 gactaatgga ttgttctgtc cataagcacg taagccgatt gactgacgta attgatccat
     5041 tgcatcaata tggtctgtcc atttagagtc cacaacacgc aagatcacga ctttttcaaa
     5101 ttccaacagt tgctctggac catttagttg agccgctttg gtattaaata cttcttgtgc
     5161 tcgttcgttt agatactctt tgatctcctg agctgttttt ccttcgatat ctgcaagagt
     5221 aatgctatct tcatggacaa gagtactgcc ggcaaaatcg atgatacttt ccaaattcca
     5281 attttctttc tctaattgtg tatgcgcatc tactacacga ctgattgtcc gtttgaccat
     5341 gttcattagt ggcttggata agcttttttc ttccatgatt acttcttgtc gctgtttata
     5401 gattacttca cgttgttcac gcatcacatc atcgtattgt aagacgtttt tacgtgtgtc
     5461 atagttattt ccttctacac gtttttgtgc agattctact tgtttcgtca gcatcttgct
     5521 ttggataaca gcatcttcct caccgatctt catccgatct aagaaagctt tgattcgttc
     5581 tgaaccgaat cgtttcatca aatcatcttc caatgacaag tagaactgtg acataccagg
     5641 gtctccttga cgtcctgcac gtcctcgaag ctggttatcg atacgacgag attcatgtcg
     5701 ttctgtcccg ataactgcta gaccaccaag ttctcttacc ccaagtccta acttgatatc
     5761 tgttccccga ccagccatgt tggtagcaat cgtcacagca cctttttgac cagcattcat
     5821 gatgatctct gcttctttaa agtgattttt cgcattcagc acttcatgag gaatacgttc
     5881 ttgattcagc atatctgata ataactcaga tgtttcaacc gcaacagttc cgactaacac
     5941 aggttgacct ttgcggtagc gatctttgat atcttgcacg acagcgtgga acttgctttg
     6001 taatgttggg taaagcaaat ctggacgatc atcacggata accggacgat ttgtcggaat
     6061 ctggtatact tggatgttat aaatttctct gaattcttct tcttctgttt tagctgtacc
     6121 agtcattccc gcaagtttct tgtacatacg gaaatagttc tggaaagtga tcgtcgccat
     6181 ggttttcgtt tcgtcttcga tctctacgcc ttctttagct tcgattgctt ggtgaagtcc
     6241 atctgaataa cggcgtccat ccatgatccg accagtgaac tggtcaacaa tcagtacttt
     6301 tccgtcttgg acaacataat cgatatctaa aagcatgata tagttggctc tcaatgcttg
     6361 atccaagtga tgggtcaatg cagtattttc aatgtcgtat aagttatcca aaccgaatgt
     6421 ttcttctgct ttttcgatcc ctgcttcggt taaactgatt gtttttgatt gtacatcgat
     6481 tttataatct tcttcttctt tcaaacgttt cacgaagttg tctgctcttg tatataaagc
     6541 tgtggatttt tctgcttgcc ctgaaatgat cagcggcgtt ctcgcttcat caatcaagat
     6601 tgagtcaact tcatcgacaa tggcataatt cagcggacgt tgtaccattt gatggcggta
     6661 aacgaccata ttgtctctca agtagtcaaa tcctaattca ttattcgtac tataagtgat
     6721 atcacaatta taagcctcgc gtttttcatc cgaagatttt gagttgatat tcaaccccac
     6781 tgttaatcct aagaaattat aaagttcgcc catttccgtc gagtcacggg ttgctaaata
     6841 ttcattgacg gtaactacgt gtaccccttc gccagtcaga gcatttagat atactggcat
     6901 cgttgcggtc aaggttttac cttcaccagt acgcatttca gggatatttc catcgtgaag
     6961 cacgattcca cccatcaatt gtacgtggta tggatataaa cctaatacac gttttgctgc
     7021 ttctcggacg actgcaaaag cttccggaag taattgatct aatgtttctc ctttttggta
     7081 tctgcccttg aattcagcag tttttgcctg taattgttca tcagttaatg ctgccatttg
     7141 gtcagcgtat gcttcaactt tttttgcaat gctatctaaa cgttttagtt ctttcttatc
     7201 gttttcgata agtgaacgaa tcaaattggc catgcgttgt gtaatctcct tttccttctg
     7261 tgtattatcc agactatgta gactttactt ttcattttat cattagttat agataattga
     7321 aatatcttaa gcgtattaaa gtaagaactt cataatttat tcatatttca tctaaaagag
     7381 gaggaaactc a
//
LOCUS       DADVXE010000101         7055 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.104, whole genome shotgun sequence.
ACCESSION   DADVXE010000101 DADVXE010000000
VERSION     DADVXE010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.104"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            413..769
                     /locus_tag="KB913_002639"
     CDS             413..769
                     /locus_tag="KB913_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6820934.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            779..1678
                     /locus_tag="KB913_002640"
     CDS             779..1678
                     /locus_tag="KB913_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBB6820935.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            2195..2926
                     /locus_tag="KB913_002641"
     CDS             2195..2926
                     /locus_tag="KB913_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6820936.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            3071..5098
                     /locus_tag="KB913_002642"
     CDS             3071..5098
                     /locus_tag="KB913_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBB6820937.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            5206..6303
                     /locus_tag="KB913_002643"
     CDS             5206..6303
                     /locus_tag="KB913_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBB6820938.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            6610..>7055
                     /locus_tag="KB913_002644"
     CDS             6610..>7055
                     /locus_tag="KB913_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820939.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT         2471 a         1128 c         1417 g         2039 t
ORIGIN      
        1 aaccctcgat attttgtgtt tcttcgataa aatagatgtt ttttatatat tccttcatag
       61 tgattcctcc aaagaagtct tttatttgat aagtttactc taccgaagag ttgttaataa
      121 tccgtgaaca aaaagtaatt ctttttccaa tagttgttaa aggtttttta ttttttatag
      181 tattttttgt tatttaagaa aggaataagg ttaaacaaat aacaggttgc tttttgggtc
      241 tttttccgtt caagaaactg aacgaagaaa agggaaagtt gtctcttttg tgataagaga
      301 aatcataata aacgaatgac ttactttcca ataaattgag aacagtcaga accagacaaa
      361 ttagttgcat ctgatgaata aagtgattat tctatgacat gaggtgatac agatgaaatt
      421 agaagtgaca aaagaagcac aagaagtatt gaagaataaa ttagaagcag acgatcaact
      481 tttattagat atcgaaaacg gtgacggtcc atttgcagaa agccaagtca gttgccaatt
      541 ggatacggca tttcgattga tcattgtcaa aaaagataca caaacagatc taagtcttta
      601 ttctgtagtg gctgatacac cagttggacc aatcaaaatc aaagacagtg caatacttta
      661 catggatgat ccatccacac ttgctttaga accaacttat aatagtttac aattaaaagg
      721 accaagcggc ttgagaaaag gcaacttgca agttgttcga aaagactaga gggataaaat
      781 gggaaaattg gcgatcatca gcgacctaca tgtggacatc aataaattcg gcgaatcaga
      841 gctgatgcag ctttggcaag ttttgcaaaa gcacaagatc actcggcttc atctagccgg
      901 agatacggct aataaagtag accgttgcct agctgttgtc gaatttttcg tcaataaagg
      961 attatctacg acatttcatt tcggcaatca cgagttggca gatgtgccca atgaacagat
     1021 gatggaccat tttccagacc cacatttttt aaatgaacgg tatattgctt taaatgagca
     1081 gaccgttctt ttagggatga atggctggta cgactatcag ttttccgaat tgaaagatta
     1141 cgaggcaatc gtacgaatga agcgtttgta ttggtatgat cggttcatcc agcgtgggaa
     1201 aacagatctc gaggtcaatg cagaaatgct tgcagctgca aaaaatttgc tagaccagct
     1261 ggaagcaaaa aaacttgagg tgattttatc cactcatttc gttcctaaac gggcatttat
     1321 catgtatcaa tctgctcctt atgagcgttg gaacaaatta aatgcatttt taggatcaga
     1381 atcattcgga gaattacttg accgttattc aaatatcaaa caagtagttt ttggccatac
     1441 gcatcgtcgc tttgaagata aatccatcgg tcacacgatt tacagctgca gaccttttgg
     1501 ttattattat gaatggcagc tgacccgaga ttttgtcttg aaagaacagt tgctagacag
     1561 ctatgatcct atgaaattac gtgtcctctt gcgtgcccat cacccagctt ttcaggccta
     1621 tcaaacacaa catttgcaag aggaatttga acaagcgatg acaatcgttc cgtattgaga
     1681 cagcattagt aatgtgtaaa agaaaatacc ttgtaaaaca taaggataag taagagcagt
     1741 agatccattt atcgtggata tgctgctttt tttgcggaaa ataatcagcg aatgtttatt
     1801 tgatcggatg atttgtaact cgcagagtac tagatgcaag cgtgtattct ttttttgaac
     1861 gataatcaca aaaaaaaata taatatacat tttttattta attataatta atattgattg
     1921 aagtctaggc agtcaagtca cattttgata gataggaggg ggacttacga attattttaa
     1981 aggctatgac agctgtattt ctagattgtg tttgcatcaa gttgcaataa aaactagaaa
     2041 tcaaatcggg ctgataatca tttataacta atcgatacat aggaccaaat ataggtctat
     2101 gttcttttat ttcataagta tcgtaaaaca gaattttgct atggattaat ccaatcgact
     2161 gatatgttta gtaaataaag aaagaggaat gtcaatgatg aaaaaagaaa tcgtattaac
     2221 agcagcaatg atgttattca gcatggtagc aagtacgact tttgtttctg caactgaagt
     2281 atacccaaag gaatataaca cagaaggaac gattacattt gaagcaggag atgagggtgt
     2341 aactcctcct gttgatccag agaatcctga tcccaataaa cctgtcgatc catcagatcc
     2401 tccaagccct ggaacaggag gggcattatc gattgattat ggatcaaaat tcaaatttgg
     2461 gactcaaaaa atttctactg cggataaaac gtattatgca gctgctgatg tgatgaacga
     2521 tgggtctaga aaaccgacat atgtccaagt gacagatagg agaagtacct tatctgggtg
     2581 gaaattaagt gtctctcaac cagaacagtt taaaactgcc agtggggatg aactagttgg
     2641 agcacagctg aaatttacga aagggcaggc tgtttctttg gttgatccaa catatacgcc
     2701 gcaaacggtg aattctgaat taacgttgac accgggagga aacaatacgt tagcaattaa
     2761 tgctaaatca ggaacaggtg tggggacttg ggtctatcga tttggtgcaa atgaaaatga
     2821 aaatcaagat gcggtacagc tttcggtacc cggtaaatct gtcaagttag cgcaacaata
     2881 ttccactaaa ttagtttgga cattagaaga tacacctaac aactagttta ctgaaaagaa
     2941 ctgttaaaaa taaatacgta gtcatattgt cttgcgaggt aatcgagcaa aaattgtcaa
     3001 aggctaggct aaatttgttt ggatacgaat agttcatcta ggaatttaac gatcaggagg
     3061 aaaagatata ttgaaaaaga ggaggatcgt gctcatttta agcagtctct tagtgactaa
     3121 tatctttccg atcatagggt actctttgga attgaatcag ttggagcatg gaaatagaag
     3181 agacgaagaa agcaaactca cttcgacatt cgacagttta atagaatcca accagacaca
     3241 agaaagcagt gaggatttaa gtatttcgag tagtggagag accactgaca acgtagaagc
     3301 tgagggttcg gacaaacaag gactagaaga tgcaccaatt tctgcggttg agctgcctga
     3361 cgatcccaat attatttcta tcgataaaat ttttcaaaca cctatcggta ctagcacgtc
     3421 catattggaa aatgggaagt tactgcagtt gaacccagca gaaaggtctc aaagaggagc
     3481 tatttggtca aataagaaga ttagtttact ctcggatttt acatttaaat cttatttata
     3541 cttaggaaat caacgagata gagcgggaga tggcatgacc tttacattga ctggcgatcc
     3601 tagaatggct agtaatccca gtcaagttat tggatcgcca ggtatgggaa ttggctcata
     3661 ttctactcgt tctggccaac cttacattgc gaatgcgctc tcgattgagt ttgatacgta
     3721 taaaaatagt ggttcttctg atcgaatgga tcgagagata actgctgata atagagggca
     3781 tggacatgtc gcttttgtca cgcctaaacc aaataataat aattattctg gagagcatac
     3841 tggcgtgacg gtagctccta catttctttc taatggcaca tggcgcttgt taataattaa
     3901 atgggacgcg gagcaaagaa gtcttactta tgatttggaa ggtgtcggtc gctcttctcg
     3961 gattatacct gatctcatta ggcagtttgg ttctacagaa gtaaattggg ggtttacttc
     4021 ttcaacaggt actttttttc aagaaaatgc tgtcgctgtc acgcgacttc catcgaatgt
     4081 cacatcaaca gctgatgtaa aagtcaacga tagtgattat ggggccatcg ctgaagctgg
     4141 aggaaacgat aagataacta tcagaaatac attgaaggtc gagggggatt ttcttgaata
     4201 taagaaaatg cagactagta tcgacctccc acaagaatta actattcccg agcatatctt
     4261 gatcaatgga aatcaaattg atgccaaaga tatcttgata accggaaatc gagtcacgct
     4321 aaatctgaca gattatttta ttgctggaga tacgttaata atcgaattgg agacaacttt
     4381 gcaggaagta attcctgaaa aagtactcac tatgcatttt gaataccttg aaaacgggaa
     4441 tttgattgag caatcgaatg aaataaacct aaagatcgca aagctgaagg agatagatat
     4501 ccatgtttat tataaagata aagacagtca gattgatatt gctgaaatga aaacaatcac
     4561 tgggaaaata ggagagaagt ataaagaaac tcctattgat attgaagggt atgtttttga
     4621 ctcggattca gcgaatacag aaggcatctt ctccgaaaat acagaggata tctattttta
     4681 ttacagaaaa ggcaaacttt atctctcaac tgctcctcaa tatgtcaatt ttggaaaaca
     4741 taaaatatcc agtagaccat taagtgaatt cggacagttt tcaggtgggt tgaaaattat
     4801 agatgaacgg gcttttggaa gttggaaatt acaattgaaa caagagaaag ttcttacaaa
     4861 tggagatttt gagcttccag aagctctttc ctttgttacc tctgaaaata caacggttat
     4921 agggacatcc gctgttacga ttttcgaaag tgatcaaaag ggtgaaagcg atttgtcctc
     4981 tcttttagat tctacagctc atcgtggaat cagaataaat attcctgtag aaaaccaaag
     5041 aatcggaacc tttgagggga aactatcttg gatacttgca gatgtcccag gaaattaaca
     5101 ggaagagaag aatataacaa aattattgag tttcaagaag ggcacaggta ccataggctc
     5161 ttgtgtccca cagagacaag attttgttat agtcttctct tacatatgat taaaggagcg
     5221 attttcttga gaccaaaaca acaattattt ataacactcc tagttatttt aggggcactt
     5281 tttaacaata tatcagtgtc agctagtgca tttaattttt cagtgacgcc gataacttca
     5341 gagaatcaaa tcgacaagag aaaaacttac ttcgatcttc aacttgatcc ggatcaggaa
     5401 gtagaagtaa aagcggaatt gagaaatgat acagaaaaag aagtgaaaat cgatatttct
     5461 gtgaatagcg caaccaccaa ttcaaatgtg atggttgaat acggaaaaaa cgagattgaa
     5521 aaagacatga gcctgatctt tgatctggta gattatgtga gctatccaca gatagtgacg
     5581 ctaaaaccta aaagtgtcca aaccgttgct tttcatgtca ggatgccgaa tgagcgattt
     5641 gatggtgtat tggctggtgg gatcacattc caagaaatcc agacggaaaa ggaccaaaca
     5701 gaaactaagg atcaaagctt atcgattgag aatgaataca cctatattat tgctttgttg
     5761 atgcaacaga cactgaacga agttgctccg aaccttactc ttcatgaagt taaaccagat
     5821 caaatcaatg caagaaatgt catcttagca aacgttcaaa atgatcaaaa aacctatatc
     5881 aatcaagtag ttattgaaac aaaaattaca aaaaaaggac attctgaagt tttatatcaa
     5941 gaggaaaaag aaggattgca gattgcgccg aatacaaatt tttcttttcc aactgcttta
     6001 aatggtcaac cgctaacccc aggtgaatat caccttacaa tgactgtttt aggaaatgaa
     6061 aatgaaaatg gaaaattttc gagaaaaaaa ggaaatacta cgatcaacta taccaatcaa
     6121 tgggtatttg aaaaagattt tacaatagac ggaaaagtag ccaaggaatt gaacacgacg
     6181 gatgttacga ttaaaaaaga caataattgg atttatatct tagtagcttc acttttctta
     6241 ttgtttattt tattatgcat acttttgttt gttttgagaa aaaaagaaga gaaagaaaag
     6301 taaggttaag ataacaaata gtaaattttt attattgtag gatggttggg ctctttttat
     6361 aacaatataa aatataccat tttattaata aaaatgcata ctagtaaatg atataattct
     6421 aataacaggt ttgatcgcga gaaaggccaa ataaaacgct ctccaaaatg ttaaaaaaaa
     6481 gacaggacga tgtatattat acaaacaaga atcgctgaca acagtgactc ggatccagga
     6541 aatcagtttt atccccagct agttggtgaa tgcatggaaa gtaatatacg tagaaagagc
     6601 tgatgactaa tgaattatga gtttttttta agcaaagaag atcacagaag ttattcatta
     6661 cttaaatatt tagaagcaag ctcaaattta tcagagtcaa tatcgaatgt tcaagaagag
     6721 ttgtcgctat cgacatttct cttgaaaaaa acgatcgata agctgaaaca tgatttacaa
     6781 aagttcgatc tagagaaaaa tttgcgagta accgtcagtg aattggatat atgtctggaa
     6841 attaatggaa aatgttctag caaagctctg ttatctcgtt atataacgga ttctttatct
     6901 atgaaaatgg tattggcttt ctttcaggaa aaatatatct cagtagaaaa ttttgctaaa
     6961 cagcatcacg tgagttattc tgtggcttat aaagtattac aaagactaaa aagaaatcta
     7021 aaaaaatatc aaattttttt tgaaaagaga aagtt
//
LOCUS       DADVXE010000102         6999 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.105, whole genome shotgun sequence.
ACCESSION   DADVXE010000102 DADVXE010000000
VERSION     DADVXE010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.105"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(120..1607)
                     /locus_tag="KB913_002645"
     CDS             complement(120..1607)
                     /locus_tag="KB913_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820940.1"
                     /translation="MQVKKKIILSILLAIIAGLYSINYFRNVHTISTSGDIAFHFARV
                     KGLSSIFSGPINFTTFNHYGSGVNYFYPYLTFFPAVIFYWISNNLIVSYILYVWLLNV
                     CTIMLMFHYGLKFLKRIDAAFIFSCLYTFYGYRTIDIYHRSAIAEAIALTVIPIVMYY
                     AYALIYEKKPCAIPLAVSMSLLIYTHVLSTFMSVIAVGLLVLGGFVVSETRKKESIRL
                     IVELSKAVGMTILLTAYFWYPMFRQIMVQSINEPDKTTLQHQALNVSDSLIGAMNNDL
                     TTFTVGIIGIISLICPLFFFKGFNRKEKVIYLSAVVSWLLSTKFFPWSLLQNTPIQMI
                     QFPWRILGFQVLFGSLILSFVFMKSTSAKQRKVVNITAIVLLLLAVSAATKANYEHKV
                     VTQRDHLVMNQENLIRYTTLLPGGLYDYAPTEALQYKEHLQNHEVRIGKEWHTMPYQV
                     MDSKIVYTVHESKGQKITLPVFDYWGTVAKVNGQKREIDNRTSVD"
     gene            complement(2046..2915)
                     /locus_tag="KB913_002646"
     CDS             complement(2046..2915)
                     /locus_tag="KB913_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6820941.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(2935..4056)
                     /locus_tag="KB913_002647"
     CDS             complement(2935..4056)
                     /locus_tag="KB913_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBB6820942.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(4058..4453)
                     /locus_tag="KB913_002648"
     CDS             complement(4058..4453)
                     /locus_tag="KB913_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBB6820943.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(4472..5278)
                     /locus_tag="KB913_002649"
     CDS             complement(4472..5278)
                     /locus_tag="KB913_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6820944.1"
                     /translation="MNKMSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALS
                     PILRKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKV
                     GTMGPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEF
                     GYKQGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQP
                     MLDKILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(5271..6059)
                     /locus_tag="KB913_002650"
     CDS             complement(5271..6059)
                     /locus_tag="KB913_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6820945.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(6073..6549)
                     /locus_tag="KB913_002651"
     CDS             complement(6073..6549)
                     /locus_tag="KB913_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6820946.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(6621..>6999)
                     /locus_tag="KB913_002652"
     CDS             complement(6621..>6999)
                     /locus_tag="KB913_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6820947.1"
                     /translation="NELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDAIYILQN
                     DLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFKQSFSVV
                     EHYYSVDIPIHEVKYVYDYVKRA"
BASE COUNT         2256 a         1447 c         1048 g         2248 t
ORIGIN      
        1 tcctgataag aaaactaatt aaaagaaaga ggtaactaca taaactaatt aaaaaagcta
       61 acttcatagt tggaggataa atggaagaaa cttcaatgat tgtttctcct tgtgttcctt
      121 caatcgacac tagtcctatt atcaatctct cttttttgtc catttacttt tgcgactgtt
      181 ccccaataat caaatacagg aagcgttatt ttttgtcctt tagattcatg tactgtatag
      241 actattttcg aatccatcac ttgataaggc atagtatgcc attccttgcc aattcttact
      301 tcatgattct gcaaatgttc tttgtattgt aatgcttccg tgggtgcata gtcataaagt
      361 cctccgggaa ggagtgtcgt gtaacgaata agattttctt gattcattac caagtgatct
      421 ctctgagtga caactttatg ttcatagttt gcttttgttg cagcagatac agccaacagt
      481 aataaaacaa ttgccgttat attaactact tttctttgct tagctgatgt gctcttcatg
      541 aaaacgaacg ataaaatcaa cgagccaaac agtacttgaa agcctaagat tcgccaagga
      601 aattgaatca tttgaatggg tgtattttgt aataaagacc atggaaaaaa tttggtggat
      661 aagagccaag agactaccgc actaaggtaa atcacttttt ctttgcgatt aaatccttta
      721 aaaaagaaga gtggacagat caaagaaata ataccaatga ttcctaccgt aaaggttgtc
      781 aggtcattat tcatcgcacc aatcaaacta tccgagacat ttaatgcttg gtgttgtaag
      841 gtcgttttat ctggctcatt aatcgattga accatgattt gtcggaacat cggataccaa
      901 aagtatgctg ttaaaagaat cgtcattcct actgcctttg acaactccac aatcaaccgg
      961 atgctttctt tttttcttgt ttcacttact acaaagccgc ctaagactag taagccaacg
     1021 gctattacac tcataaaagt ggaaagaaca tgtgtataaa tgagtaagct catactgact
     1081 gctaatggaa ttgcacatgg ctttttctca taaatcagtg cgtaagcata atacataact
     1141 atcggtataa ccgtaagtgc aatcgcttca gcaatagcag aacgatgata aatatcaatc
     1201 gtacggtacc cataaaatgt atataaacag ctaaatataa aagccgcatc gattcttttt
     1261 aaaaatttta gtccataatg aaacatcagc atgatagtac aaacattcaa tagccaaaca
     1321 tataagatat aactaacgat taaattatta cttatccaat aaaaaatgac tgccggaaaa
     1381 aaggtcaagt agggataaaa ataattcact ccgctcccat aatgattaaa cgtcgtaaaa
     1441 ttgattggac cagaaaaaat tgaagataac cctttgactc tagcaaaatg gaaggcaata
     1501 tcccccgatg tagaaatagt atgaacattt ctaaaataat tgattgaata aagtccagca
     1561 ataattgcta ggagaatgga caatattatt tttttcttta cttgcattac ttaattatat
     1621 actcctttca tggattgctt tatctagtat aacttaaatt ttaaataaat cgttatttat
     1681 ttttactctc acttaaaaaa gcactaaaat tataagagag ggaggtaatg gtctgaacac
     1741 caagaattgt tccaacatcg aattgcttaa ctaatgagtt caaagcttaa ttatgtggct
     1801 cttatattta ccgagcgtgg attgcgatct ctttagcgaa acaaacatct ttcataaaaa
     1861 aaacagccat atccgctttc ttggatatga ctatttacta ctactttact atctttcatt
     1921 cttcttgtct cacttatgat aaggcgctgg gtatcatgag tgaatgatat tgctgaatac
     1981 aaatagtccg accacattaa gttgatcgga cttcataagc attttattga ctaatacttt
     2041 tttgcttaag aattgattct aacatctttt gctaaagtta agcatcctat agttcctgca
     2101 ttatctgcta acttaggtgt gacaatgtat tcttcgatat ttggcgtatc gacatagccg
     2161 ttaattagtt ctaaaaaacg tctttgtact ttctttttca gatgttcttg ttgcatgaca
     2221 ccaccaccaa aaattataat atctggtgaa agcatcaggg tcgtattaca ggcacattgt
     2281 gcaatataat ccgcctcgat ttcccagaac ggatcttcta tagaaagatc ttgtcccttg
     2341 gttcccgtac gcatctcgat agcgggtcca gatgccaacc cttcgagaca atcatgatga
     2401 aaaggacaag taccagagaa agtatctcct gaatgtctct taactaacgt atgccccatt
     2461 tctggatggc taaacccttc aacaaaaatc ccatcttgta tagctcctcc accaattcca
     2521 gttccaacag tgtaataaac aacactggat aaaccttttc catgacctga aacatactcc
     2581 ccgtaacaag cagcattcac atcggttgtc caggcaattg gaatttcgaa atgcttattc
     2641 aacgttccaa caaaatcaaa atttttccag gcagtttttg gagtagaggt gatatgtcca
     2701 taggtctttg attcacgatg gatatcaatc ggtccaaatg accctactcc aatgctttct
     2761 aattgttctt tatagtgatt aaagaaatca attaccaaac tcattgtttc attcggtgta
     2821 gttgtaggaa aactcactct ttctaaaacc tttaaatcat cattgccaat ggcacaaaca
     2881 aatttagtcc cacctgcttc tattgagcca tacatttctt actccaccgt ccttttatct
     2941 aggaattcgt tcttccctgt ctaatagttt ttcgaaaaac tcatgtggtt ccttttggta
     3001 ccaataggca acagaagaaa tatcgtcttg acgctcataa agcttgatgt catcatttcc
     3061 tagggtttgg aaagtaacac gtaaattttc tttgaaacta atggggtcgg gtaaatgcca
     3121 gcggtacaac ccatgcatcg gtaaagcatc atcgccaaaa ccatgaactg gatttggatt
     3181 aggttttcca gcactaaaat aatcccgggt gtgatctctt ttagattgaa aaggatagcc
     3241 cataaatagc gtattaaaat tttgagcata tgccctttct ccaaagttct ttttatggaa
     3301 agcccaagcg ccgccaaaat aatcttctgc tcctgtagat gttattgtag ggaaatcttc
     3361 atctccatct atataaaact taaattctcc ttccccccac cagtatcttt ccaatgcgca
     3421 caaagcaaag taggttccta cataataccc agtgcctttg attccatcaa taagggtgta
     3481 atcttttcct tttgtcgtga tgggttcacg gttccattta gcatgaaaat acatcgcatc
     3541 atccggtact tcagtcaatg cataattaaa tgtataaaaa atgtgcttaa taaactcagg
     3601 atgttcattc gttaaagtaa tcttagcttt ttttcgaaat ggcatctcaa aatagcaatt
     3661 catccctgat gttggattca ctacgattgg taaggaattc acttcgcatc ttgtcccaaa
     3721 cccattacaa aaaaaatctc ctaatggact ttctacagaa ggagtggatt catcatccca
     3781 ataaatacgc aaaattaaat cacgtaagac gaaactccca gcgattgttt tgtctgtcac
     3841 tgtcatccaa aaatgacgta aaattccagg gccttccatt tctgctaaag taattgtctc
     3901 tccagcattt atcggaacag aaggtgaccc ttttctccca attcctagat gactcgctgt
     3961 cattgccgct ttcccttttt caccattttt attttctggt gaaatagttc tactttcctc
     4021 tcccttgtgg agccatatat tatttaaaca attcatttta ttcgtcctct atcctttctt
     4081 cacttttttg attattcata tagatgattt gttgttgtgc ctccgcaata attgctccaa
     4141 tatctaaatt atcatttcct aactgcaaag cgattgacat tgccaaggga agattcattc
     4201 ctgcaattac gtgcactctg tcagaaatat aggtaaaaaa cttttgattt acacttcctc
     4261 cagccatgtc agttaaaaca attatttcgt ctgtagtatc cactaactct ttaatttgtt
     4321 catctatatc atcaatttct tcgacatatg cacataagct actaatttga ttatgcatac
     4381 ctgttaaaaa ctctagtgtc tctttaaaac cctcagctag tattgaatgg ctagcaatga
     4441 tcaatcttct cataattcaa atccttttcc tttacgctaa tattccaaat gcagccataa
     4501 ccatcgcaaa aacaataacg agtagaatca aaatggtcat actgattttt ttcttactga
     4561 gtagataata tgctgcagca gtaataatta ctggaattaa tgttggtaaa attttgtcca
     4621 acattggttg gattttcata ctaacttcac caaaagtgaa tttaagtggc gttgaaacac
     4681 tgataactga agcaattaat gatccaacta ctgttagccc caatactgaa gcagcttcag
     4741 ttaaataatt aatcttttca ccgtattcag taacaatctt cattccctgc ttataaccaa
     4801 attcaaagcc tctcattcgg aaaaagaaga ttaccatgat taaaatgaac cataaaaaga
     4861 ttcctacagg attattttct aaagccatat aagccgcaat tgatcccatg atggttggga
     4921 tcatcgtcat caaaagagag tccccaatac cagcaattgg acccatcgta ccaactttaa
     4981 agtcattaat cgcatctttt gcttctaatc cttgcttttc ctccattgca acacaagcac
     5041 ctaaaataat ggctgccagc caaggctgtg tattgtaata ctgaaagtga ttatttaaag
     5101 cttcgatgta ttcatcatca tctttgtata attttcttaa aataggtgac aatgcgtaag
     5161 tcacagatgc accttgctgt gtttgataat taaaggtaca aactgacatc aaccaacgat
     5221 agttcgcttt cctaagatcc tttttcgtta cttgatattt ttcgctcatt ttattcatcc
     5281 tccccaataa acccaacatc agaagctccc gcagaagcag tgatttgtgc atctttttca
     5341 gctctatgat acacattaaa tgctaaagcg aatcctatga tcgccgctcc aataataggt
     5401 accttcaaaa aagcggctaa gaaaaatcca acaagtaaat aactaatgta tcgacctgta
     5461 ggcataaagc gtaacaacat cgcaatacca acagcaggca acatttttcc ggctaatgtt
     5521 agcccatcca taaaccaatt aggtaaaaca tccaaaacgt aattaacagc agactgtcct
     5581 aaagtaacgg caataaatac tggaattgct gcagataaac caaagaaaat tggccccaac
     5641 cacaaaacac tattcatttt cttaaattct cgtttattcg catattcctg tgatttgcga
     5701 acaacaaaac catttaagat tttgacaatt acatctagtt gcacccctaa catacctaca
     5761 ggtagtccta ttgctaatcc ggcttctact ccaagctggc taccaaatgc cgttgcaata
     5821 attgcgcacg ttccatagtc cggtacagat gagccaccaa aaccggcaac tcctaatgac
     5881 atcaattgaa ctgtaccgcc aactatcaaa cctgttttta tatcacccat caaaattcct
     5941 gtgaataatc cccaaaaaac tgcgtaattt acaaagatca tcggaatccc ataataatca
     6001 acatgtttaa taaatgctaa tatagtcagc ataataattt gaaaaatagt aaaatgcatt
     6061 atccttactc ctttatccta attttgattg aatttcctgt gccttatccg ccggaacaaa
     6121 ttgtgtaaca atttctacac cagaatccaa caatttttta tacgtgctga tattttcatc
     6181 tgatgcatag gctctagaag atagctgtaa tgcattatct ttaacaacag taccgccaac
     6241 aattagtcgg tcaattctaa taccgttatc tactaaatga aggattgttt ccggctcttt
     6301 cacgatgaca aatacttttt cctgatcgta tttccccttt ttaaaattcg caatcgctgt
     6361 ttcttcagtg ataattgata cagccattcc agcaggtcta gctaaacgca tacttgattt
     6421 ttggatgtcg ttatttgcga cagaatcatc gatcaccatc actctgtttg ctttagacat
     6481 tggtgcccat tgcgtgacaa taatcccatg caataaacgg ttatcaactc tcgacataac
     6541 aatactcata aatacttcct cctttatctt tcattttctt acaagcaatt accatgccaa
     6601 aacaaaaaga acttgataaa tcaagctctt tttacataat cataaacgta tttaacctca
     6661 tgaatcggga tgtcgacact ataataatgt tcaacgacac tgaaagattg cttaaaatgt
     6721 gtctgaaatt tttgaaattc ctcactcgtt tcattgaaat aaatttcatc ttccaaagta
     6781 ttttgtttta ctaatcgttc aattaagcaa ctaatgtgaa catataatcc gaaacacgta
     6841 ttattatcaa atgaaattcc tagatcattt tgtaagatgt atatagcatc tgaaacccgt
     6901 tctaataatt tagtcggatt taatatggtc aattgctcca ttaaattcgt tagactaaaa
     6961 ttcttcagaa tattattgtt caaaactttc agttcatta
//
LOCUS       DADVXE010000103         6955 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.106, whole genome shotgun sequence.
ACCESSION   DADVXE010000103 DADVXE010000000
VERSION     DADVXE010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.106"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            142..615
                     /locus_tag="KB913_002653"
     CDS             142..615
                     /locus_tag="KB913_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBB6820948.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            612..2744
                     /gene="feoB"
                     /locus_tag="KB913_002654"
     CDS             612..2744
                     /gene="feoB"
                     /locus_tag="KB913_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBB6820949.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            2746..2880
                     /locus_tag="KB913_002655"
     CDS             2746..2880
                     /locus_tag="KB913_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBB6820950.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            2974..3618
                     /locus_tag="KB913_002656"
     CDS             2974..3618
                     /locus_tag="KB913_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6820951.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            3805..4998
                     /locus_tag="KB913_002657"
     CDS             3805..4998
                     /locus_tag="KB913_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6820952.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            4991..6718
                     /locus_tag="KB913_002658"
     CDS             4991..6718
                     /locus_tag="KB913_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBB6820953.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
BASE COUNT         2238 a         1227 c         1559 g         1931 t
ORIGIN      
        1 cacaagtata attgacattc tcaattaccg agagtattct atgtgagaat gattctcatt
       61 tatttgcgta acacgtaaga aaattagaac atataatgaa tgattttaat acatgattta
      121 tttcacaaga gaggaatcaa tatgcagacc ttagcgcagg caaagcagaa tttcgtttat
      181 caagtcgaac gaatcgaaac agaagaaaaa acaaaacgcc atttgcaaaa tatcgggatc
      241 gttgccggaa gtaaaatcgt cgtcgtcaat ttatcaggca acaatgccat tttactggta
      301 aaaagtcatc gagtggcagt aagtcgggaa atactaggtc aaatctttgt caataaaaag
      361 actgcttcct ctgaaagctg gacttctctt gatcaattaa aagcaggaga gactgggatc
      421 gtcgtagcaa tccacggaca aggcgcagtg aagcgacggt taatggatat gggattgacg
      481 cgaaatgtaa aaatagttat ccgaaaacta gcccctctgg gagatccaat cgaactgaca
      541 gtgcgagggt atgaactgac gttacgaaag tcagaggccg aactaatctt gatacaaagg
      601 gaggaaaaag aatgaatatc gcgttagtcg gaaatccaaa cagcgggaaa actagcttgt
      661 tcaatctctt gactggttcg aatcaatatg tagggaattg gccgggcgta acagtagaaa
      721 aaaaagaagg atcgttgaaa aaaaatccga acattcatat tcaggaccta cccggcatct
      781 attctttgtc tccttataca ccagaagaag tgattgcaag agattatttg gttcaggaac
      841 agcctgaact gatcatcaac attattgatg ctaccaattt agaacgaaat ctttatttaa
      901 ctacgcagtt attggattta gacattccta tgatcattgg tctgaatatg atggatgtca
      961 tcaaaaaaga aggaaaaaaa atcaatctag aaaagctttc ctatggtctt ggtgtaccag
     1021 ttttaccaat cagcgtattg aaaaagcaag gaatcgaaaa actaatcgaa aagattcagg
     1081 agtctgcaaa aaagcggcct tctattcctg ttccctgtac atatgatcca cgtttagaag
     1141 cagctttaca tgaaattgaa gatgtactag gagaacaaag cggcaagaaa cgctggtatg
     1201 caatgaaata ttttgaacga gatcagaagg taagagagga ttacgagata gcagtttctc
     1261 agcaaaaaga gatcgagcaa ctgatccagt taacagagaa actattggac gacgatagtg
     1321 agacgattct ggtcaatgaa cgttatgaat ttattaccca actatgtaca ctctgtgttg
     1381 tgtcaaatga ttctttccaa ttatcgatga gtgacaaaat cgatcagatt gcaacgaatc
     1441 gttggttagc cttgccgatc ttcgcatttg tgatgtggct gatctattat ctggctattc
     1501 aaacagtagg aacaatgggg acagattgga tcaatgacac attgtttggt acatggttac
     1561 cagaacatgt tggcagattg ttagctgaat ggcaagtagc gggatggatg caggagctga
     1621 tcttgaacgg catcatcgca ggcgtgggag cagtgttagg atttctaccg caattgatta
     1681 tattgttttt atgcttgagc tttctggaag actgcggata tatggcgagg atcgcttttg
     1741 tcatggatcg acttttcagg aaattcggtc tttcaggaaa atccttcatt cctatgctga
     1801 ttgctacagg atgtggagtg ccaggcgtca tggccagtcg cacgattgaa aacgagcaag
     1861 atcgtcgttt gacgatcatg gtcacaacct tcatgccttg ttctgcaaag ttgccgatta
     1921 ttgccttagt agcaggggcc ttttttcctc atcaatcttg ggtagctcct tctgcctatt
     1981 ttcttggtat gactgcaatt attttctctg gaatcagctt gaaaaaaaca cgtttgtttg
     2041 ctggagatac agctcctttt atcatggaat tgcccgcata tcattttcct caatggtcag
     2101 cggtcctaag acaaacctat gaccgcagca agtcttttgt taaaaaagca ggaacgatta
     2161 tctttgtttc tagtatcgtg atctggttca gctcttctta taatttttat gctcaacctg
     2221 tttctgaaga ccaaagtatc ttagcctttt tcgggcgaat cctggcagtt gtttttcagc
     2281 cgcttggttg gggaaactgg caaggaacag tcgcagcgat tacaggattg gtcgctaaag
     2341 aaaatattat tggcacattt ggtattttgt ttggtcatgc ggaagtatcc gaaaatggca
     2401 gagaaatctg gcaagtgcta caacacacat atactcccgc agcagcttat tcattgttag
     2461 ccttcaattt actttgtgcg ccttgttttg cggcaattgg ggctatccat cgggaaatga
     2521 atgccaagaa atggacttgg atcgccatag gctatcaatg cggtttagct tatttagtta
     2581 gttttgtgat ttatcagttg ggacacttat tggagggtgg acaggtagcg ttagggacgt
     2641 atcttgctat tttactgatg ataggactcg tttatgtttt gttccgtcag ccaaaatcca
     2701 agaaccagtt ttatactata ttgtcattag aaggagagga ataggatggc gacattctta
     2761 ttaagtgtgt taatctttgg aagtgcaggc gcaattgtct atactcgttt aaaatccggt
     2821 aagaattgtg atgactgtca aacagcttgc ccagtaaaaa aggaacagat caagcgatga
     2881 tcagtcgttg caagaggcta ttctcccctt ttttgcttat tttgctagag catagtaaga
     2941 tgagggaaag taaaaaaaga aagaggaaag aaaatgtctg gaaagaaaaa aatcgtccgc
     3001 ccgcgctacc agcagattgc tgttgattta gccgaacgta tcgttgaaaa ccgatataaa
     3061 gtgggtgaga agatccatgc ccgctcaaca cttgccagta cgtacaatgc ttctcctgag
     3121 actacccgca aggctatcaa tgtgctggta gatcttggaa tcatggaagt acggcatgga
     3181 agtggggcat ttgttgcttc gaaggaaaaa gcaaaagatt tcctattgca atatcaagat
     3241 gtacaatcca tccaagatac aaaagcagaa atcatggcaa gtgtggagaa gcaacaagat
     3301 gagctgaatc atttttctca attattggat cagctggtca atcaaacgaa gcgaatacat
     3361 aagatgaatc ctttacttcc gtttgaatta tctttatcag aaaaagcaat gcatctggac
     3421 cgttcaatta gcgagttgaa tatctggcag gcgactggcg ccacagttat cgcaatttct
     3481 cataatgaag aactgcttgt ttcacctggc ccctatgcta aatttacggc aggggacatc
     3541 gttcatttta ttggaaatga atatacacta cagcgtatga caaacttttt ttacccggag
     3601 catcagcttg cagaatgatt gtgtgaaata ttaaaaaaat attaacttgg ctaaaccttt
     3661 tatttacaaa gatttagcca agtttttttc agtttggaca agcaaatttc tttcattttt
     3721 gacaaagtga ctacatgatg ttaacatagt gtggtcactt ttttcagaaa gaaaaatgaa
     3781 tttacataaa aaaggagaat ttgtttggta aaagtagaag taaaacattt aacaaagata
     3841 tttggtaaaa agacacaagc cgctttagat atgatgaatg atcaccagcc gaaaacggag
     3901 attttaaaga aaaccggtgc aacggttggt gtgtatgacg tgaattttga cgtaaaagaa
     3961 ggagaaatct tcgtgatcat ggggctttcc gggagtggga aatccacatt gatccgtcta
     4021 ttgaatcgtc tgattgagcc aacttcgggc agtatctata ttgatggaga agatgtatcg
     4081 aagttaagca aagaagaatt gcgagaagtc cgtcgtcata aaatcaatat ggttttccaa
     4141 aacttcggtc tgtttccaca tcgaacgatc ttggaaaata cagaatacgg gttagaagtc
     4201 cgtggtgtac ctaaagaaga acgacaagaa aaagcagaaa aagcattaga aaattctagt
     4261 ttgctttcat ttaaagacca atatcctagt cagttatctg gtgggatgca acaacgggtt
     4321 ggcctagcca gagctttagc aaatgatcct gagatcttgc tgatggacga agcgttctcg
     4381 gctcttgatc cgctgatccg gcgagaaatg caagacgaat tactggacct gcaagccaat
     4441 gttcaaaaaa cgattatttt cattacccat gatttgaatg aagctttacg gattggggac
     4501 agaatcgcct tgatgaaaga cggcgaaatc atgcagatcg gaacaggtga agaaatattg
     4561 accaatccag caaatgatta tgtacgtgaa tttgtggaag aagtcgatcg ttccaaagtg
     4621 cttacggctc aaaacatcat ggtacctgca ttgacgacga atatcgaatc tgatggacca
     4681 aacgttgcat tgacaaggat gcgtaatgaa gaagtcagca tgctgatggc tgttgacaga
     4741 aagagacacc tgaaagggat catcactgca gatcaagcgt tagaagctag gaagcaaaaa
     4801 cgtccattga tcgacttcct agatgaaaat gtgacggtga ttgggaaaga catggtggta
     4861 agtgatattt tcaatattat ttatgactca ccgactccac ttgcagttgt agaggatgga
     4921 aaattaaaag gtgtcgtcat ccgaggtagt gtgattgaag cattagcaga aacaagcgag
     4981 gtgagtgaac atgaataatc tattgaacta tcaattacca gtggcaaact gggtagaaaa
     5041 tatcacagaa tggtttacga caactttttc tggcctattt tcatttttac aaacgattgg
     5101 acaggcagtg atgtcgggga ttacaaattt actgttagtg attccagctc ctttgtttat
     5161 cttgttattg acggtagcag ctttctttat ttctaagaaa cgtccaggac ttacgttgtt
     5221 cacattaatc ggtctatggt ttatttataa ccaaggtcta tggaatgatt tgatgaatac
     5281 tgtcacactt gttcttttat ctagtgtgat ctcgatcatc attggggtac cattagggat
     5341 cttgatggca aaaagcagta aagcccaaag tattatcaaa ccgatccttg actttatgca
     5401 gacaatgcca ggattcgttt atttgattcc agcagttgca tttttcggta tcgggatggt
     5461 tccaggggta tttgcctcag tcatctttgc tctgccacca accgttcgtt ttacgaattt
     5521 agggattcga caagttccta aagaattagt agaagcttct gattcattcg ggagcacaag
     5581 tcgtcaaaaa ctattcaaac tagaattgcc tttagctaaa agtacgatca tggcagggat
     5641 caatcaaaca acaatgctgt cactttcaat ggtcgttatt gcctctatga tcggtgcacc
     5701 cggcttagga cgcggcgtat tatcagcatt gcaaagagca caagtcggga atggatttgt
     5761 caacggggtt gcattagtta tcttagcaat catcattgac cgttttacac agcatttgaa
     5821 ccagccaaac aataaaaaag ctgcaggagc aacaacacag aaaagtaaaa aacgtcaagg
     5881 actgatcatt ggtgctgtag tagtagtgat cttaggtgcg attggtatag ggagtttttc
     5941 atctgccaaa gaaacaaaac gtatcaactt atcttatgtt gaatgggata cagaagttgc
     6001 ttcaacaaat gtagtcggtg aagtattgaa acaaatgggc tatgatgtaa cgatgacgcc
     6061 attagataat tcaatcatgt ggaaatctgt ttcaaatggc gagtcagatg ccatggtttc
     6121 agcttggcta cctaaaactc atggttcaca atatgcacaa tataaagatc aagtcgaaga
     6181 cctaggtgcc aatttgacag gagcaaaagt tggtttagca gtgccagcct acatggatgt
     6241 aaattcgatc gatgagttaa ccgatcaggc aggtaagaaa atcataggaa tcgagccagg
     6301 agctggtgta gttacggctg ctgaaaacac gatccaaaaa tatgacaact tgaaagactg
     6361 gaaagtagag acatcttctt caggagcaat gaccgttgca ctaggtcaag cgatcaaaaa
     6421 acacgaacca attgtagtta caggatggac acctcattgg atgtttgcca aatatgatct
     6481 gaaatactta gaagatcctg aaaacggaat gggaagcgaa gagcagatcc atacgatggt
     6541 tcgaaaagga ttgaaagaag accagccaga agcttacaaa gtattagaca atttccattg
     6601 gtcagaaaaa gatatggaaa aagttatgtt ggaaatcaac aatggaaaag atccacagca
     6661 agcagcaaaa gactggatca aagagaacca agaattagtc gaaagctgga aaaaataaaa
     6721 agacagacac gaaataaatg gagcttccaa aattggatca aatatccaaa tttggaagct
     6781 ccatgttcgt ctctatcttt tttgtctata aaaaaagaga atgcgtagct catcttcgaa
     6841 acgttcaaag acgccgacaa actattatga atttatgggt gcgagtcaaa gagatcgatc
     6901 gtaggtatga aagactaatg tgattaaagt ttattatgta cgaagtgcat tctca
//
LOCUS       DADVXE010000104         6810 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.107, whole genome shotgun sequence.
ACCESSION   DADVXE010000104 DADVXE010000000
VERSION     DADVXE010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6810
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.107"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            43..933
                     /locus_tag="KB913_002659"
     CDS             43..933
                     /locus_tag="KB913_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBB6820954.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(1006..1830)
                     /gene="nadE"
                     /locus_tag="KB913_002660"
     CDS             complement(1006..1830)
                     /gene="nadE"
                     /locus_tag="KB913_002660"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBB6820955.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(1842..3314)
                     /locus_tag="KB913_002661"
     CDS             complement(1842..3314)
                     /locus_tag="KB913_002661"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBB6820956.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(3951..4313)
                     /locus_tag="KB913_002662"
     CDS             complement(3951..4313)
                     /locus_tag="KB913_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBB6820957.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            4536..5288
                     /locus_tag="KB913_002663"
     CDS             4536..5288
                     /locus_tag="KB913_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6820958.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(5428..6351)
                     /locus_tag="KB913_002664"
     CDS             complement(5428..6351)
                     /locus_tag="KB913_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6820959.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(6366..6638)
                     /locus_tag="KB913_002665"
     CDS             complement(6366..6638)
                     /locus_tag="KB913_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820960.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         2084 a         1352 c         1163 g         2211 t
ORIGIN      
        1 atatgttaat atataagaaa aaccttttaa gaggtgatat atatgcaact acaaataaac
       61 gaagaatcct taccggtata tgaagcatta gctagtaaaa caaggatcaa gatcatccag
      121 ctactttcca aaaaaaagat gaatgtcaaa gatttggcaa aagaacttgg agtgagcagt
      181 gctatcacga cgatgcacgt gaaaaagcta gaggaagcaa acatcatcaa aacagaaaaa
      241 gtaggacaac aaaaaatttc gagccttcgt gtcgataaaa tcgatatcag ttttccagaa
      301 aaaatattca atgcttttga tacgaaagaa acatcgatac ctattggtca ctatacaaat
      361 tatgcaattg aaccaacatg cggtttagct acgatccatg attttatcgg gaaagtggat
      421 gaaccacgct attttatgga tcctcgaagg atggatgccc gcattctctg gtttaccagc
      481 ggatttgtcg agtatcaggc acctaatttt ttaaatacag aggatacatt ggagatgttg
      541 gaagtttctg tggaaatttc ttctgaattt cctttttcaa atgacaattg gccttcagat
      601 atcactttca gcctaaatgg tgtggagcta ggaacatgga cgagccctgg agattttgct
      661 gatatccgcg gtaaatatac gcctgattgg tatccagata atcttaatca atacggcttg
      721 ctgaagacga tccgaattac caaacacttg acgaatatga atggagaacc cttgtcaaac
      781 atcacgatca acgacatccc taaagagcaa gacacttggc atttgcgaat cgaagtgaaa
      841 gacgatgcca aacatgtggg gggctgtact ttatttggta aaggattcgg taattacgat
      901 caggatatca aattaaaagt ttactacagc tgatattttt cttttctatt ttataaaaca
      961 aaaacagcca atccctatga agggacggct gtttttgctt tattgttatt tccagaaatc
     1021 atccaaaacg gaaattggca aatgtcgttt atgttgtgtc ttgttccacc atgcttcgat
     1081 tttttcttgt gcttgagcgg gaacttcttt tccttctaga taatcatcaa tttcattata
     1141 tgtgacacct agtgcgactt catctgcaat cattggtttc ccatcttcaa gatctgcagt
     1201 cggaattttt gtgtataatt tttccggtgc attcaatgct tgaagcaatt gtttcccttg
     1261 tcgtttgtcc aaacggaata atggcaaaat gtcggctcca ccatcaccaa atttcgtgaa
     1321 gaatccagta atgttttctg cagcatgatc tgtccctaat acggctcctg ctctttctcc
     1381 agctacggca tattgcgtaa tcatacgttg acgtgctttg atatttcctt tgttaaaatc
     1441 gctgattccc acacctgctt cgcttaatac ttgtacttgt gcatcaacag ctggtttgat
     1501 atttactcgc agactaacat cgggctggat aaagtcaaga gcagcttttg catcttcttc
     1561 atctgcttgt tcaccataag gaagacgaac agcgataaat tgatagtttt catcttttgt
     1621 ttcttcacgc atttcttcca tcgttagttg cgccaaacgg cctgctaaag tagaatcttg
     1681 gccgccgctg atacctagta caaaagtttt aagaaacgga tattttttca aatatgcttt
     1741 cataaagtca atacttttac gtatttcttc ttttggatca attgttggtt tgacacctaa
     1801 ttcattgata atttctgtct gcaggctcat ttattctcct cctatgcttc tgtatgaagt
     1861 tctgctacgc tttttttcat tcgttccatg atagccattt tatggttcca gcattcagta
     1921 gacagatcga ctgggtattt ttgcggattc aagtctcgtt tatactcttc ccatagtgaa
     1981 tctagatttt cttttgtata ttctttgatt tcgtttagtg caggtaattc gtaaactctt
     2041 tttccttcga taaagatatc ttgtaaaact gggcgagctg taaagtctcg aacagtttta
     2101 ttgataaacg tatgcactgg atggaacatg aagatagctt cttcttctcg agggtcttca
     2161 tcccataatg tcacgtagtc tccttcagat ttcccatcaa aatttcgagt gatgcgccac
     2221 acttgttttt tccctggagt agttactttt tctgcattgc ttgataactt gatcgtatcc
     2281 atcatttttc cttcatcatc ttcgatcgat actagcttga atactgcacc aagggctggc
     2341 tgatcatagg ctgtgatcaa ttttgtccca acaccccata catcaatttt agctttttgc
     2401 atctttaaat tcaaaatcgt tgcttcatcc aagtcattcg aagcatagat ttttgcttcc
     2461 gtaaatccgg ctgcatctaa ttgttcccga acacgcttag atatataggc catatctcca
     2521 ctgtcgatgc gtacgccttg gaagttgatt ttgtcaccta attctttcgc cacgcgaatc
     2581 gcacttggca cacctgattt caacgtatca taagtgtcga ctaagaacac gcagtcttta
     2641 tgggttttag cgtaggccat aaatgcttca taatcatttc cataagattg gactaacgaa
     2701 tgagcatggg tcccgctagc tggtatccca aatatcttcc cagcacgtac attgcttgtt
     2761 gcatctgctc cgccgatata tgccgctcta gttccccaga ctgctgcatc cagttcttgt
     2821 gcccgtctag ttccaaattc caatagtgga tcttctccga tgacagattt gatacgagct
     2881 gcttttgtcg cgatcaacgt ttggaaattg accatattca acagtgctgt ttctactaat
     2941 tggcagtgcg ctaaaggccc ttccacttgg attaatggtt catttgcaaa aactagttct
     3001 ccttcacgag cagaacgaac tgttgcttta aattcaaaat tttgtaaata ctccaaaaaa
     3061 ccttcaggat agacttctaa tccacgcaag taagcaatat cggaatcatt gaacgtcaga
     3121 ttctctaaat aattgactaa ccgttccaat cctgcaaaaa ccgcgtatcc gtggttaaaa
     3181 ggcatttctc gaaagtaaca ttcaaaaaca gcatgtaaat cagctcgacc taattcccag
     3241 tatgtctgca tcatattgat ttgatataga tccgtatgca gcgtcaaact gtcgtctggg
     3301 taagtattat tcatcttgta ttactcctct tggcaagttt tcatttccta cccattataa
     3361 caaaaaaaat taataggaaa agaaatcttc cattttttct gaaaaagcac atgttttacg
     3421 gatatttctt gctaaaaatg aactccatct gctaaaacta tcctttctta ttggtattta
     3481 acctaaacga gaaagaatac ttattttatt caatgtatcc gagacacgaa gaaattagcg
     3541 ttttctattt ttcttacttg ataaaataag tagattttcc tactacaatc gtagccgtta
     3601 agataccgat gattgaacaa atataaccaa atgtctctac aacataatca atggcaaaag
     3661 tttttgaagc aataatacgt ctttcctttt ttgcttctta tccccaaaga aacggatata
     3721 acttattatg tattgaattt ttttggaaag gcgaattatg acaagatata ccttgcgttg
     3781 aaaaaactcg cggaaaaaat atcacacgtt tttaaaaaga tacaaagtaa gaaagcagct
     3841 gtcaatagaa tggaaacaaa aatggcgaga catcaatcag tctcgccttg ttttttattg
     3901 tatacattag atatggagca ggttaccata aagatgatta ttagtcgtta ttaaatagaa
     3961 tccttcgtat ttttttgttc tatcactaca atatctttat ttggacgttt gaattgtatt
     4021 ccggcacgtt ctagctcctg tttcactcct acatggactt tgacatcttc tcgtgtcatt
     4081 tttaaaacgt gatgaatcgc atagtcgatt tcttgccttg tgattttttt cttcgtattg
     4141 atcatcacga cttgcttttt atcatatgtg tctaccaata gcagttgtgt tcgatctaac
     4201 gaaaataatt tgtaataatt aatagccgta ttcccaaaaa agaattccac tactttagga
     4261 taaaatgtct taatatttaa attactattc acaggtgttt cgattagctt catctcattc
     4321 ctcttttcta tatagtcgat ttagatccaa tcttaagtta tgttaccatc tttcctagca
     4381 ttaaggaatc ggttacaatt gaacctttaa agacaaaagg atttaccttt tatcacttaa
     4441 tagtataaca taatttcgtg agaaaaaaat acaatttttt cttgaccatc tcgttacgta
     4501 aaggattatg cttacatttg tcaggaggaa aaataatgga gtacacaata aagaaaatgt
     4561 cagagatatc aggagtcagt ccgagaacct tgcgctttta tgatgagatt ggactgctaa
     4621 aaccagctag gatcaattct tcaggttatc ggatttatgg caaaaaagaa gtcgatcgtc
     4681 tgcaacacat cttattttat cgaacaatgg cattcaagtt ggatgatatc caagaggtct
     4741 tagacaatcc atcttttgac caccagaaag ctttaatcaa gcatcagcaa atgttgctgg
     4801 aaaaacgggc acaaatcgat accctcttga caactgtcca acagacactt gatatgtacg
     4861 aaggaggaag aaaaatgagt gacaaagaaa aatttgaagg gtttaaacaa caaaagttga
     4921 aagaaaatga agaatcctat ggacaagaga ttcgacaaaa atacggaaaa aaaaaggtta
     4981 cagcatccaa tgaaaaatgg atgaatatgg ataaagaaac gtatgaagaa atgcaaactg
     5041 ttgaaaagca gatgttattt gatctcactc tttacttaaa agaaccagaa gatgaaagct
     5101 tagcagaccg tatcttccaa gctcataaga agtggttctc ttacagctgg cctgaatatc
     5161 agccaaaagc gcataaagga ctaggaatga tgtacgaagc cgatgaacgg ttcactgcat
     5221 attatgacga gcgaagtggt catggtgcag caaaagcttt aaatgaaatt atccaaaaaa
     5281 aggcgtaatc ttttacatga tccaacaaaa aagtacacgt aaaatgacct aataacaaaa
     5341 cagcagacac ccaagttaga tttttatgct aacttttggt gtctgctcca ttctttcaca
     5401 agttttttca tcctacttta aatatattca tcgttgaata aacgtataag gtattttcac
     5461 tttatccttt ttttctgtaa gaaacaattg aaatgccatt tctccgcaag cttccagatg
     5521 gtggtcgatg gttgggaaac caagaagctc gctgatcagc aaattatcgc gtccaatcac
     5581 cactggtgtc ttatcttgca gatagctttg caagatgcct gctgcaacca tatccgaatt
     5641 tgtaaagaca ccatcaactc caagctcttt aaaaaagaag cctgcttgtt ttcctttctc
     5701 tgcatctata caatcccaaa aaacaagtga ttcatcaaaa gatggaaaaa gttgatgaca
     5761 tagctgcaaa gtgatttttg agttataact tagcctgcca cttcgcccca acgtgatgcc
     5821 caattgcttt ataccttgct gcttcaaata agtaagacct tctgtaattg attgttctcg
     5881 atcaataaag acacagcttg cctgttttcc cttgatttct tcacaaaaaa ctagaggtcc
     5941 atatttttga tatgccaata aatcatctag tgtattggca cgagacgtaa tgatcaatcc
     6001 atcgaaagct ttagctgcaa attcttcaag ataccttcgc tctttttctt tatgatagcc
     6061 cgtcggtaaa agtgtcactt tgtaatcata atcaaacgct gcttcaatga tcccactgat
     6121 caactgatca aaatacggat gattggtata aggcagaatc actccaatgc ttttcgtttt
     6181 tccataactt aactgtctgg catttgcatt agggatataa tcgacttctt tcatgaccgc
     6241 aagtatttct ttcctttttt cctcatctac atatggatgt ccattgatta cacgtgaaat
     6301 agtagaaact gaataacctg tgagctttgc gatatctcga atgtttgcca ctgctgcttc
     6361 gccacctata caaaaagatt ttcttgtaaa tagtctacca cagctggacc gcattcaaaa
     6421 aactgataca tttttccttc atgcgaaaaa ctgatccgct gcccgcccca atatatatct
     6481 tttgtcaaat tttcgatttc attcattggt atttctttta ctatattcct attcaaccct
     6541 tgaaaactgt acaacgttaa tacggatccc ttgaactcga caaacgcata aaaataattg
     6601 ttcgttgtgc catctgttat ctctacataa gtattcattg caagccctcc ttttgatact
     6661 ttgagtatag tgtatgaaac gcgtctcata gcaaggagtt tgttttgcca aagaaaagtt
     6721 ttattcctct ttcattatta ccaaagtctc ttattttaaa ttgaatacat tataatgata
     6781 ctgtaaatat atctttatta ttagtgaatg
//
LOCUS       DADVXE010000105         6550 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.108, whole genome shotgun sequence.
ACCESSION   DADVXE010000105 DADVXE010000000
VERSION     DADVXE010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.108"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(99..1229)
                     /locus_tag="KB913_002666"
     CDS             complement(99..1229)
                     /locus_tag="KB913_002666"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBB6820961.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="KB913_002667"
     CDS             complement(1878..3080)
                     /locus_tag="KB913_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6820962.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="KB913_002668"
     CDS             complement(3140..3343)
                     /locus_tag="KB913_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBB6820963.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="KB913_002669"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="KB913_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="KB913_002670"
     CDS             4880..5692
                     /locus_tag="KB913_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820964.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1984 a         1328 c         1022 g         2216 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa
//
LOCUS       DADVXE010000106         6501 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.109, whole genome shotgun sequence.
ACCESSION   DADVXE010000106 DADVXE010000000
VERSION     DADVXE010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6501
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.109"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..748)
                     /locus_tag="KB913_002671"
     CDS             complement(<1..748)
                     /locus_tag="KB913_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6820965.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPY"
     gene            complement(759..1427)
                     /locus_tag="KB913_002672"
     CDS             complement(759..1427)
                     /locus_tag="KB913_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBB6820966.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(1557..2141)
                     /locus_tag="KB913_002673"
     CDS             complement(1557..2141)
                     /locus_tag="KB913_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6820967.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(2472..2705)
                     /locus_tag="KB913_002674"
     CDS             complement(2472..2705)
                     /locus_tag="KB913_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBB6820968.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(2720..3670)
                     /locus_tag="KB913_002675"
     CDS             complement(2720..3670)
                     /locus_tag="KB913_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBB6820969.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(3667..4509)
                     /locus_tag="KB913_002676"
     CDS             complement(3667..4509)
                     /locus_tag="KB913_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6820970.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(4511..5230)
                     /locus_tag="KB913_002677"
     CDS             complement(4511..5230)
                     /locus_tag="KB913_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6820971.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            5922..6080
                     /locus_tag="KB913_002678"
     CDS             5922..6080
                     /locus_tag="KB913_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6820972.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            6152..>6501
                     /locus_tag="KB913_002679"
     CDS             6152..>6501
                     /locus_tag="KB913_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6820973.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFG"
BASE COUNT         2268 a         1116 c          853 g         2264 t
ORIGIN      
        1 tatagggaac ttcaatcgaa ctattaaaaa tgtcaaattt ccttaatgcg ttattgtttt
       61 cagtttttaa caactgaata gttgtagttt ttacagttct atttttaaca aatagaactt
      121 gatcaattaa ttctttcaaa tagtaaaaac gatgttcagc tataacaata gtaaatcctt
      181 tattttttaa atcacaaagt aagtcagcaa gtttcttagt cgctttgaag tccaaatttg
      241 aagacggttc atccaatata attaatttag agtttagcga taaactacat ccaatagaaa
      301 ttttctgccg ttcaccactt gatagcgaaa aaatgttttt atctaatata tttgaaagat
      361 ctaataattc agctaattca ttgattcttt tatccatatg ctcttttgta aatccaaagt
      421 tttccatcga aaatactaac tcactcgttg tatttgttgt aaagaattgt cctctaggat
      481 cttgacttac gtagccaata ttttttgata tactttcttg tgttaaggat tgtagcgagt
      541 tattttcaaa taaaatttcc ccaaccaatt ttccgtcata aagtcttgga ataagtccat
      601 tcattaactt taatagtgtg gatttcccac tcccagaaga accagtaatc aatgtaagac
      661 tgcctttttt tattgaaaaa ttaaggtcaa caagcgcttg ttccttaaca tccttatatg
      721 aaaaagaaac attgttaaat tcaaacaatt ctttcacctc aaatcaaaat acttaagaaa
      781 aaaatagtaa cggaaaacag gatgatatag tctaataagc tcatgtttgt tttatagtaa
      841 gaacttcttt tcacaggaga ttctatcccc tttgttattg cattagcggt catttcttca
      901 gcaatcatag ttgcacgtat aagaacggga actaacagaa attccaaata ttgcagaggc
      961 tgaaaaaaag acaagcgaat gtttctcatt tttaaagatt ctttaatcat tcttatttca
     1021 gaacgataag tcggaaagaa tctgatcact actgtaatac ttaacattat ttttttcggt
     1081 aaatgtattt tttctaaaga ggataataat tcattgctag tatagacact aaccaacaac
     1141 catgagatca ttacgaccgg caacattcga aatacaatat ataaggatgt cgcaaaaaat
     1201 atagtaaaaa actctatctt gatagcatca ataattttca ttactaaaaa cagaactgaa
     1261 taaatcaaga tgaaataaat acatgtcttt attttacgaa acatcaatac taaaactgta
     1321 gcaataatga aacaccccac ttgaaatata tttccctttc ctaaaaaaat aatgaccgga
     1381 aaaaaaatat ttaaagtaat caaggttaac ggattgattt ttgacactct ttcacctcca
     1441 aaaaataaga tcgcactgtt atcttaagct gataaaaatg caccgttatt cagataacag
     1501 tgcgatctta tcaaaaagca taactgagaa caattctcaa tgcaagcttt ttttaattaa
     1561 ctcagtaatt caatccaccc aggaacagaa aattgataca atcttctggt taatagcata
     1621 gtcttttctt ttgaatagct atgcttcaat atatcataga atgtagcgta gaatgagtaa
     1681 atgtagaagt ggatttcttc ttcattaaag actaaatttt gattgatcat tccgatagtc
     1741 tttaacttat ctagacaaca gactgtcttt ttcgtcacaa atgatgtaat tttttcaaca
     1801 atatcttgat atttggttcc agctgattgg aataaaatca aatcgaatat acgtttattc
     1861 tcaaaaatat aattaataaa tggatctaat tcattgaagt tctctctcca acttttctct
     1921 atatctatat tttctaagtt taagaggtat ttggtaaact cttcattata catattaata
     1981 agcgcattaa tatgcggctg aataatttct tcaaataacg cttccttaga agtaaaatgt
     2041 ttataaaaag cacccgtagt tacgcctgcg gtcaggcaca gttgccttat cttagtttgc
     2101 tgaaatcctt ctttttcaaa atggcttagt ccactttcta ttaacttttg gtgagttata
     2161 atataatctc tggtttctat gggtacttcc tcctaataag atgaattaac tttattatct
     2221 tacacaggac ttgaagtttc aatcgttaac gtttattact gaactcattc cttagagcta
     2281 aactaatgag aaagagcaga ataactgata caaaaagcaa tcctacaaga attaatagac
     2341 tcatctaaat cattcacctt ttctaaaata atccgagaaa gatttaaaaa aattatatcc
     2401 agctattagg ataagtccta tcataatcac tccaatagcc attttcttat cctccctaaa
     2461 aataaagtct tttacttaaa accttttttg taatcgtcaa taaatttttt ccctttatca
     2521 gttaattgaa atcctatatc taaatagtcc tcatatctaa gtttagccag catctcactt
     2581 acagatgctg gactaacact tagaactttt gctaaatcat tattttttaa tttctttttt
     2641 ctttttgata attcctgaat tgctagtaaa taaattagta tagtagtcgt tttaatttgt
     2701 accataccta ccctccaaat tatttcgaaa ggccttcagc aattttatcc aggttccatt
     2761 tcatcatcgc atagtaacta tcaccatctt gtcctttttc tgcaattgaa tcagtaaaaa
     2821 tcgttgaata gataggaata ttggtatctt ttgatactgt tttcattggt ctatcatcca
     2881 cactgctttc tacgaataag gagggaactt ttgttgtgcg taatttttca actaagtgtt
     2941 ttatttgatc tggtgttcct tcttcttcag tgttgatttc ccaaatgtaa gcagaaggca
     3001 cattatacgc tttcgagaaa tatttaaagc atccttcact tgtaacaatc atttttttat
     3061 cattcggaat tgaagcaaat ttagatttag cttctttgtc tagagaatcc aatttttcaa
     3121 tatacttatc tagattttct ttatagaatt ttttattatc aggatctttt tccgctaact
     3181 gtttttcaat atttttagcg taaataatac cgttttctaa atttaaccaa gcatgaggat
     3241 cttccttccc tttctcactc tgaccctcta agtaaataac atctatgcca tcacttgctg
     3301 caaaatagtc tttgttttcc tctttgttcg catttttaac taattttgta aaccaagcat
     3361 ttcctccagt ttccaagtta acaccgttat aaaaaatcaa atctgctttt gaagtttttt
     3421 gaacatcttc aggcaaaggt tcatattcgt ggggatcttt cccaataggt acgatactgt
     3481 gtaaatcaat tttatctttt gctatatttt cggtaatatc tgctaaaatc gaattagtaa
     3541 ctactacttt taatttttcg ttcgaagcca ctttatcttt gtctttacta tttattgaac
     3601 atgccccgaa tataaaaaga gcaatcaaaa tccccagact tcccagtact gctttccatt
     3661 ttctcatcat aacgatctct ccttctttct taaaaatttt tgttttggtg agattagaaa
     3721 actaattaca aataagaatg ccgctgttaa aacaatactt gatcctgctg ctatgttaaa
     3781 actataacca ataaacaatc caagcaatga tgaacttgct ccgactgttg cagaaataaa
     3841 tatcatagtt ttcaagctat ttgcatataa atatgctgta gctgctggtg taattaacat
     3901 tgcaacaatt aatatagttc ccacactttg catagctgtt actgctacta aagttaatag
     3961 aaccatcaat agataatgat aaaaactgac attcatccct attgcttttg ccattaatgg
     4021 atcaaaagaa gtgattaata attctttaaa aaatagaact actataacca acactaaaac
     4081 cgaaacgcca attgtaatcc acttatcaat atcttgtaca gctaaaatat ttccaaataa
     4141 aatatgaaat aaatccgttg agctatttgc aactcctata aggataactc ctagtgctaa
     4201 aaaagaactg aaagtaatac caattgctgt atctcctttt attacactat tgctttttat
     4261 aaaagtaata atgatagaag ctaatagacc aaatacaatc gcaccaataa aaaaattaat
     4321 acctaaaata taagaaattg ctactcctgg caaaacagca tgagaaatag catcacccat
     4381 aagagacatt cctcttaaaa taataaaaca acctactgtt ccagaaacaa tccctataac
     4441 tacagatgta attagagcat tctgtaaaaa gtgaaagtca tacagaccat taataaaatt
     4501 ttgaagcata ttattccccc tctccaataa atatagtatc tccataggct ttttttaaat
     4561 tttcttcatt aaatacagat tctacacttc cgtgagcaat tagatttcga ttcaaaagaa
     4621 taatattatc aaaatacttc tttaccttgc ttaaatcatg atgcacaatt agcactgttt
     4681 ttccctgatg tttcaatttt tttaacgtat ccataattat tcgttcacta actaagtcta
     4741 tccctacaaa tggttcatct aaaaatatga aatccgcatt ttgagcaaga catcttgcta
     4801 aaagtacacg ttgaaattgt cctccagata attctcctat ttgatgatta gaatattttc
     4861 ccatatcgac cttttccaaa gcctttgaaa ctctttgcca ttctgcattt ttaattcttt
     4921 gaaaaacttt cattccggca tatgttccca tagatacaca ttcttttact tttattggaa
     4981 aagtaaaatc aatatcagct ttttgctcta catatgcaat cttcaccagt tttttattga
     5041 tatcttcatt attaatggag acctctccct gatgagggat aatatttaac attgctttaa
     5101 gcaatgtgga ttttccagca ccatttggac caataatacc tgttaaagca ccttcttgta
     5161 tttttaaaga aatctcgttc aatgctaaaa aatcgttata acaaacatta agctttttca
     5221 cttctaacat aactttctcc ttctaaatga taatgattat cacgatcata tggtatacaa
     5281 aaattatatt ttagtcaacc ctaaatttta tagtttagat ttttttctgt tgctgaagat
     5341 tagaatgaca aaactatttg aaactacgcg tatagtaagt agctttcaaa atatataaaa
     5401 aaggagcgtt ctcaaatgag aacatgctcc taaaactact ttattggcgt atggaaaaat
     5461 tatacttgaa gtggatagcg ggttgaataa gttgataagc atcaaaacat ttataaaaat
     5521 tattcaagac tatgtctgtt ccatatacaa atatgaaaat cagtaaactc catttaactt
     5581 ttttcgtagt gtgtcttttt atacatgttt atcgttatta atagtgaata ggaaaaaaac
     5641 tatttttgat cattgacaat taaatacaat ttttgaataa cgatccctgc tattcgagct
     5701 agaaactcaa gtacgccatg acctgattag cgacaaatac ttagagattt ctttttgttc
     5761 tgggaaaaca aaatgccatg acaatagcag caaataatga tacttccgta aggctcgccg
     5821 taaactgggg agaggtgaaa ttcctatgtg cttacccaaa gcaattcaaa aatttcataa
     5881 ctactatttt aggagatgat tttatagaat ccagagtcta cctgaataaa aaacaaacct
     5941 gtgcatttct aggaatcgat aataatactc tagataagtg gattcgtata tataatttcc
     6001 cagtaataag agttggtggt gtagttcgct ttgacgtaga agatattaaa gactttatga
     6061 atacatttaa aataacttga aattttcttc tcgccgcata tactaaaatt agtgaaatat
     6121 actgccttac tttttttaag gagtgaggat tttgcctaca aagctttcaa atgggaaata
     6181 taaaactaat ctgagatatc caaaaaggtt taaagaaata acaggaattg catcagaaaa
     6241 gtatcaaaaa acatttccaa ataggcaatt ggcgattaaa gccgaaaatg atatgaagaa
     6301 gaaaatagaa aaagttttga gagaggagaa tgcaaactca ttagaattaa aaggaaaaat
     6361 aacgtttaaa aaattttacg aatctaaatg gcttcctaga tatgaattag gtcaaacaat
     6421 tagatcaaac aggcctccta gtgatataac cattagtaat acaaaagata tatttcggtt
     6481 gcatatttta cctatgtttg g
//
LOCUS       DADVXE010000107         6452 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.110, whole genome shotgun sequence.
ACCESSION   DADVXE010000107 DADVXE010000000
VERSION     DADVXE010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6452
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.110"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..2643
                     /locus_tag="KB913_002680"
     CDS             <1..2643
                     /locus_tag="KB913_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HBB6820974.1"
                     /translation="LQLLNTLGISYVNLRTFSTLNKKTVSHIFSTADSQAIINYLEKQ
                     KLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKEGSATDSEKKKA
                     ENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTIQNFLQLLHRRF
                     GVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPDNIDRSNCFKIL
                     EQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIKEGDHKGVTLLI
                     FDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKYPLPKPVNPSVE
                     SLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQKVITLVLAYYVD
                     HCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENAPIFFEHESLGW
                     KKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKYVLGTNLELAWS
                     IGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGNPTTVLRNMNAT
                     NKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLDSNCQLMPQETF
                     SVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKSLSSNTFGWGIK
                     LFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYSGALLIQDILGY
                     PLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLTNSDNKHTPSTI
                     WGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNMCAEKGRRTKRI
                     HMNRQVLPTYEILLPSSLKSYFRL"
     gene            2825..3064
                     /locus_tag="KB913_002681"
     CDS             2825..3064
                     /locus_tag="KB913_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820975.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            3080..4453
                     /locus_tag="KB913_002682"
     CDS             3080..4453
                     /locus_tag="KB913_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6820976.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            4457..6091
                     /locus_tag="KB913_002683"
     CDS             4457..6091
                     /locus_tag="KB913_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6820977.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6254..>6452
                     /locus_tag="KB913_002684"
     CDS             6254..>6452
                     /locus_tag="KB913_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820978.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
BASE COUNT         2257 a         1054 c         1298 g         1843 t
ORIGIN      
        1 ttacaactgt taaatacact ggggatttct tatgttaatt tgagaacttt ttctacatta
       61 aacaagaaaa ccgtttctca tattttttct actgcagatt ctcaagcaat tattaactat
      121 ttagaaaaac agaaattgtc tgaaggtaca gtaaacataa cttataatcc tattaaacaa
      181 gaggtgatta cacaaaaaaa gcattctgtg agagacaatg atattgaaaa aattcggttt
      241 gtatttattg atattgaccc taaaaggaaa gagggaagtg caacagatag cgaaaagaaa
      301 aaggcagaaa atgttatgga acaagtagaa cgttatttga aagaaaagag aatagaatca
      361 tttgtaaaag ttgatagtgg gaatggctac catatttttc ttcccataaa tgaacaacca
      421 aataatcacg agacgattct tactattcag aattttcttc aattacttca ccgaagattt
      481 ggagtagaag atgaagttga tattgatact tctgtttata atccttcaag attatgcaaa
      541 ttagttggta caccagcggt caaaggaaag tccacaaaag agcgtccgca tcgtttatct
      601 agtttccttt ctattcccga taacatagat agaagtaatt gttttaaaat tcttgaacag
      661 atagttgaag aaaattccat gatgtcaacc tctagagtaa aaagccatcc atcttttaga
      721 gaagtgttac cttttattca agcagactat aaacaatggt tagctcacta tcctgaatta
      781 acttatacca taaaagaggg cgatcataaa ggagttacct tacttatatt tgacgaatgt
      841 ccattaagaa aacacacgaa taattctaat ggttcttgtt tgtctgttac ggctgataat
      901 aagattcgat ttcattgtct gcatgcttcg gataaaaata aagatattca agactttgta
      961 aaaaaatatc cgttgccaaa acctgtaaat ccttctgtag aatcattaga atccaatcaa
     1021 gaatattatt ttgaccagtt taaactgaat caagaaggag tatttttggt gaaagaaggt
     1081 caagaagaaa aagttgcttg tccgatgttt attaagcaaa tacgcaaaaa tatcgaacaa
     1141 aaagtcatta cacttgttct tgcctattat gtcgatcatt gttgggatga aatagaaata
     1201 gaaggtggat gtttacaaac taataatttt aaacaattag caaaacatgg cttaatcatt
     1261 aaagctagaa gagaagctga agtcgttgac tttttacaga ttcaacggga gaatgctcca
     1321 atcttttttg aacatgaatc tcttggctgg aaaaaagaaa atgaagcaat gatttttcag
     1381 ttacaagatt cttttggacg tgaaattcct tctgtattaa ctaaaaactc atgctaccaa
     1441 ttaacaacta atggtacaga agcggaattt gacgcattgg ttcataagta tgttttagga
     1501 acgaacttag aacttgcttg gtcgattggt attgcttcta ttgtgttagg ctatttaaac
     1561 gttacgaagg ctaatacttt tttgagttta ctaattaacc tacagggcaa gagcacaacg
     1621 ggtaaaacca ctacgttaca ctttattgcc tctttatttg gaaatccaac tacggttctt
     1681 agaaatatga atgctaccaa taaagccatt ataaagctag catcaaacaa tcagggaggt
     1741 gttccactaa tactagatga gttaggagca gcaactcaaa ataactttag ctcgttgatc
     1801 tatcaattag cttcaggaga agaaaggcta agattagatt ctaattgtca gcttatgcca
     1861 caagagactt tttctgtttt gacccttacc tcttctgaag agcgtttgga aaattatttc
     1921 aatgagaaat taactggttt gaaagttcga tatatcgaat tttctgatat caagtttaca
     1981 aaggatgcga atcacgcaga gaaagttaaa agtctttctt ctaatacttt tggttggggt
     2041 ataaagttat ttcttttgaa actctttgaa caagggatta caaaaattga agcaactttt
     2101 gtcgaagctc aaaaaaaact atgggctgtt ttacctgaac attctttgaa gcaacgcatt
     2161 ggtaataatc tagctttgat ttatagtgga gccctcctaa ttcaagatat actgggctat
     2221 cctttacgat tagagcatat acagacggtg cttattaatt cgtacgaaca gttaattgta
     2281 gatactagtt taggaagtga gcaaacggta tttgaccgag tgaaaacatt gttggtgatg
     2341 aatagccata aatttttaac aaacagtgac aacaaacata cgcccagtac gatttgggga
     2401 aaagtatcaa ttcaaaaaaa tggggatatt aaggtaaata tttttcctat cccgtttgag
     2461 gacttgttaa ggcgagaatt tcaagtaaag gatctaacct atctttttag gcaattgctt
     2521 gattcgggta atatgtgtgc agaaaaaggg agaagaacga aacgtattca catgaatcgt
     2581 caagttcttc caacatacga gattctatta ccttcttcac tcaaatcgta ttttcgattg
     2641 taatttagaa taaaccaaag tatgaaagtg aggcaccatg ttatggaaat atttcttatt
     2701 gatttagcaa aacaactgat tacttatctg tatgatagcg agcaaaccca aacggaagta
     2761 aatgaagctt gatctatgct tcatttactt cattcaatca aacatgaaag aaaggaaaat
     2821 tctaatgact aaaaataaaa tgacactaaa agcagaggtt cttctgtata ttcaagaaca
     2881 tttttcaaat caagcctttt ttacaaaacc aatttacttg gatttcgaaa taagaggggt
     2941 atctgctgga tctatcgggg gtactcttca agcgttgaag aacgaaggat atttagaaaa
     3001 tcactttgtg caacgttcgt tcaatagaag agtcgtgaaa aaatggtatt tagttcattc
     3061 atagagaggg gaatcaagca tgcgtgtggc ttgttatgat cgaacgtctg tttatgaaga
     3121 agcgaaaatt agtaatgacg ctcaatatga tgcagtgaaa gagtatgttt tagagaaata
     3181 tgaacaaatt ccccaacgat tttcagacaa aggagaatca ggggaaaaag cggagcgtcc
     3241 agcttttcga cagcttagag cttgggtttg tgcgtcagaa gaagaggggg tgatctatgt
     3301 ttggcgttat gatcgattgg cacgtcaagc caaaatagcc ttagaattta ttgagttgtg
     3361 ccaacaacat caggttcaag tgtattcgat ttctgaacct cttcctgctt ctttctcaca
     3421 cgcgtcaacg aataaactat ttgtgcaatt attgttcact tttgcagaac aacaacgaaa
     3481 cgtcattatt gagaatgttc gtgccggact ttcctataaa aagcaacaac ggcaatattt
     3541 gtcttctgcg gtaccatatg ggtatcgttt agtgaatggg aaaatccaac aagaagtaca
     3601 cgaagcaagg attgttcgct atatttttca actttatttg accaaaaaat atggctacaa
     3661 aaagctttgt caacgattga cgcaacaaaa gcttttcttc cgcgaacgtc cttttcagcc
     3721 ctatcatatt tatagtatcc taaaaaatcc attgtactat ggcgaaatca aaggaggatc
     3781 tttggggaag tatctaggaa cctttgaacc gattctctcg aaagcaacct ttttacaagc
     3841 ccaagagatt cgccaatcaa ggtgtacagc taaaaaagat acgtatctgt acttattacg
     3901 tcaaaaaatt cggtgtccct tctgtggtcg tcatctgagt tcgaagtatc aatggaatac
     3961 aaagaagacg aagacgcttc attattatca ttgtaccgac cgaagctgcc aaggaatttt
     4021 tcttcgggca gaaagggttg agtcagaagt attggaaaag atacaggctt tttttcaata
     4081 cgaaggcgtc tatcaagcct tgattgccca attaacgcaa caattagccg aaaagcgaaa
     4141 agatgaaaaa cgcaaagtaa tccaacaaaa gaaacaagaa gcacaatgga ttaaggcatt
     4201 tgaagagggc aattgttcac tggaagaact caagcaacaa ctgcaagctc ttcaaaagcc
     4261 gatgtctact tcttcgtttc tttcactcca acagtgtgaa gcaaaagtga aagaatggct
     4321 tcaactaaaa gacctctcta gtcgacaatt attatgtgac tatgtttgtc ggattgaggt
     4381 aacaaaggat aaaacagttt gtgggattta cttccgacaa ctgacacaaa atattttaga
     4441 aaggaacgaa tgatctatgg aaatgataca aaccaaacga gtcgcattgt atattcgcgt
     4501 gagtacacaa gaacaagctt tagaaggaca tagtattcaa gcacaagaac aaaatggacg
     4561 acagtttgcc gaacggatgg gctatgaagt ggtagaagtt tatgccgatg aaggaatcag
     4621 tgggaaatcc acaaaaaatc ggttcgccta tcaacgaatg atgaacgatg ctcggaacca
     4681 tcgttttgat ctactagtga tttggaaatt gacccgtctc ggacgcaata tgttagatgt
     4741 cttacaaaca gtcgaggaat tattgcgata tgacgtagga ttacattcga tctcggaaca
     4801 atttgacgtg accacttcga caggtaaatt gatgttacaa ctccttggga gtttcggtga
     4861 atttgaacgc aaccaaattg cggagaatgt tcaaatgtca atgcaaagct tagtgaaaga
     4921 taaaaagcgt tatgcaggag gccgacgttt aggctatgtc agtggtattg acacgaatgg
     4981 tcaaaaacaa ttggtcattg aaccagaaga ggcgaaaatt gttcgtctga tctatgcaaa
     5041 atatttaggc ggagcagggt atcgagcgat tgccaatttt ttgaatcgtc aaggatatca
     5101 aacagtcaaa aagaatgctt tttctaccac ggcagtcaaa gatatcttac gcaataaaat
     5161 ttatgcaggg tatttagaat atgcgcgcta catcaattgg gaaaccaaac gacggaaggg
     5221 gaagaatccg agaccgattt tagtgaaagg aacccatgaa ccgattattt cggaagaaga
     5281 ttatcaaaaa gtacaagaac gccttgcttt agaaggaaaa caacccaaat ggaaccatac
     5341 aggtgaaaat gtattgacag gcttgttacg ttgtccagaa tgtggcgcac cgatggcagc
     5401 gagtaatgtc acaaataccc taaaggatgg cacaaagaaa cggattcgat attattcttg
     5461 ttcagtcttt cggaataaag gagcaagtgt gtgtcatgcc aattcgattc gtgccgaaca
     5521 agcggaaaca tttgtcgccg accgattaaa ggagatcgtt cagctaccag aagttcttcc
     5581 ccgattggtg gcagcgttaa atgaagaaat agtgcgacaa agccaaccat tggaacaaga
     5641 actcgtggtg ttactggaac gaaaggaaga attgaagact aaaattgaaa aatgggaagc
     5701 tgctttggaa gatagtcctg aattgtttcc gatgttaaaa gaccgcttag acgaattgac
     5761 tgaaaaacga cgacagttgc acattcgaga aaatgaaatc ttagggatct ttcaacaagg
     5821 agagccgatt caagtcaaag atgtccaacg gatattgact agtttggatc gttttcttgc
     5881 ccagagtgag aagaagcaaa tcaaagcctt gtatcgtacc tttatagaga aaataacctt
     5941 tgatcctaac cataaggaga tgttggaaat tacgatgaaa ttcacgcatg ccgtggtaca
     6001 acaattgaat gagcaatatc aaatagccgt atccaaaaca aaggatacgg ctatttttgt
     6061 gttaaaaaca ccctttacgt taacgatcta gtctaggtta tatcaaacaa cgttagaggg
     6121 gcgctaacgc ttctctagcg atttgaaatc gttagagaag tagttaggga ggtccttatc
     6181 ataaataggg atatttatta atgaatattt gaaatataat tgtatataag aattaaaaag
     6241 agtggggata gatatgaaaa agatgggtaa gtgtatttta tgtgaaaaat acactgaact
     6301 tactaaagaa catgtaccac ctaaaaaatc agggaatact ggaggtaaaa agaccagaac
     6361 tggtaattta gatgatttcc ttaagagcga ttttacaaaa ggtgattttc cgaaggggat
     6421 taaaaggaaa cctcaaggaa atgtttatta ta
//
LOCUS       DADVXE010000108         6387 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.111, whole genome shotgun sequence.
ACCESSION   DADVXE010000108 DADVXE010000000
VERSION     DADVXE010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.111"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            330..1175
                     /locus_tag="KB913_002685"
     CDS             330..1175
                     /locus_tag="KB913_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6820979.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="KB913_002686"
     CDS             1456..2676
                     /locus_tag="KB913_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBB6820980.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="KB913_002687"
     CDS             2673..5393
                     /locus_tag="KB913_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6820981.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="KB913_002688"
     CDS             5377..6321
                     /locus_tag="KB913_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6820982.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2379 a          987 c         1231 g         1790 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttc
//
LOCUS       DADVXE010000109         6173 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.112, whole genome shotgun sequence.
ACCESSION   DADVXE010000109 DADVXE010000000
VERSION     DADVXE010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.112"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            725..811
                     /locus_tag="KB913_002689"
     CDS             725..811
                     /locus_tag="KB913_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBB6820983.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="KB913_002690"
     CDS             complement(932..1621)
                     /locus_tag="KB913_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820984.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2780)
                     /locus_tag="KB913_002691"
     CDS             complement(1866..2780)
                     /locus_tag="KB913_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBB6820985.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="KB913_002692"
     CDS             complement(2762..3142)
                     /locus_tag="KB913_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBB6820986.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="KB913_002693"
     CDS             complement(3592..3879)
                     /locus_tag="KB913_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBB6820987.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="KB913_002694"
     CDS             complement(3899..4123)
                     /locus_tag="KB913_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBB6820988.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="KB913_002695"
     CDS             complement(4578..4748)
                     /locus_tag="KB913_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820989.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="KB913_002696"
     CDS             complement(4763..5296)
                     /locus_tag="KB913_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBB6820990.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="KB913_002697"
     CDS             complement(5317..6159)
                     /locus_tag="KB913_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBB6820991.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DADVXE010000110         6086 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.113, whole genome shotgun sequence.
ACCESSION   DADVXE010000110 DADVXE010000000
VERSION     DADVXE010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.113"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            126..1133
                     /locus_tag="KB913_002698"
     CDS             126..1133
                     /locus_tag="KB913_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6820992.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            1145..2149
                     /gene="neuB"
                     /locus_tag="KB913_002699"
     CDS             1145..2149
                     /gene="neuB"
                     /locus_tag="KB913_002699"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HBB6820993.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            2146..3294
                     /gene="neuC"
                     /locus_tag="KB913_002700"
     CDS             2146..3294
                     /gene="neuC"
                     /locus_tag="KB913_002700"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBB6820994.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            3267..3944
                     /locus_tag="KB913_002701"
     CDS             3267..3944
                     /locus_tag="KB913_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBB6820995.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            3934..5076
                     /locus_tag="KB913_002702"
     CDS             3934..5076
                     /locus_tag="KB913_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBB6820996.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            5089..6066
                     /locus_tag="KB913_002703"
     CDS             5089..6066
                     /locus_tag="KB913_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6820997.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
BASE COUNT         2260 a          768 c         1168 g         1890 t
ORIGIN      
        1 ttttaatcaa tcaaatgttg attcgttacg ttttgacatc attattgata attagtttag
       61 ttatatattt tttaaagatt aagaatcgaa ttatagatga ctataattca taggaggaga
      121 tataagtgtt taaaggaaaa acaatattag taactggcgg aactggttcc attggaagtg
      181 aaattgttcg tcagctttta aaatatgaac caaaagctat cagaatttat agtagaggtg
      241 aagaaaaaca attttatatg caacaagagc tctcaaatca cactaatttg agatttttaa
      301 ttggtgatat cagagactct caaaggattg attatgcatg tcgtgatgtg gatattattt
      361 ttcatgctgc cgcaatgaaa cacgttccag caagtgaata taatcctatg gaagctgtaa
      421 aaacaaatgt gatgggaact caaaatgtaa tagatgcagc gatcaaaaat aatgtaaaac
      481 attttgtagg tatcagtaca gataaagtag tgagtcctac taacaccatg ggtgcgacaa
      541 agttattgag tgaaaaatta ataatagctg ccaatcagta taaaggaaaa acagaaacaa
      601 tattttcttg tgtaaggttt ggaaatgtca tggggtcaag tggatctgtt attcctcttt
      661 ttagtaaaca aataaaaaac aataaagata ttactttgac agatgttgat atgacacgat
      721 ttatgatgtc aataccggat gctgcaagat tagttctgtc tgctgctatg aattcaaaat
      781 ttggagaaac atatgtctta aaaatgccgg caatcaatat tttaacttta gctcaatcat
      841 taataaaaat atataatgat acacatgatg aaaaatatag aggtgaaata aaagttgtag
      901 gtatcaggcc aggagaaaaa ttatatgaag agctaatgac tacagacgaa attgaacgct
      961 catatgaaaa tgataaaatg tatatcattc caccacacta tcatgctact gacgaactgt
     1021 acaaagatta tgaaaaaatt aaaatcactg catactcttc agatgcaaca gaattaatga
     1081 gtggacagga atttattaga atcgcaaaag agaataatgt cgtgacttgg taaggagttt
     1141 tatgatgaaa tcagaagtat atgtaattgc agaaattggt gtaaaccata atggaagtct
     1201 agatttagct ttagaaagta ttgataaagc taaagaatgt ggagctaacg cggttaaatt
     1261 tcaaacattt aaaacgaata agctagtttc caaaaaggct ccaatggcaa aatatcagaa
     1321 ggataatctt aaagaggaca gttctcaatt tgaaatgcta aaaaaattag aattatctca
     1381 atctgatttt attagaataa aagattattg tatacaaaat aaaattgatt ttttgtctac
     1441 tccttttgat gaagaaagtg cagactttct aaaacaaatt ggtgtacaag gatttaaaat
     1501 tggctcagga gatttaacaa atttaccttt tcttagaaaa atagatatgt atgggttgcc
     1561 agttttatta tctacaggta tggctgatat tcatgaggtc agtgaggctg tagattgttt
     1621 catagatagt ccagttacta ttttacattg tacttcaaat tatccggcta gttctgaaga
     1681 tattaattta ttggcgatta acacattaaa agaaatgttc gggatacccg ttgggtactc
     1741 cgatcattca ttgggatatg atgttggtat ttgtgctgtt gcgatgggtg ctaaggtaat
     1801 tgagaaacat tttaccttgg ataaggaact acctggtcca gatcataaag cttctttaga
     1861 tcctcaggaa tttgcagatt ttgtaaagca tattagaaac actgaaatat ttttaggtga
     1921 tggtgttaag cgagcaatgc cttctgaact tagtacaaaa gaagtatcaa gaaaaagcct
     1981 agtggtcact gagaatttaa atgtgggaga tattcttaca gagaaatctc ttacaataaa
     2041 acgtcctgga aatggaatag ctcctaagtt tttatatcaa tatattggca aaaaagttaa
     2101 aagaccaata agtgcagata gtgttctgct tgaggaagat gttgaatgaa aaaaatactt
     2161 atagtaagtg gaacacgagc tgattatgga atatataaac ctgttgctga gaatttacta
     2221 caagataatt gggatgtatc atttgttgtt tctggaatgc atttatccca taaatatgga
     2281 tttactaaag aattgatctt agctgacgga tttagaatta gtggagaagt tcaaagtttg
     2341 tttttagaga acaataaggg aaacatggct cggtctgtgg cattagagat aaatggtttc
     2401 acaaatatat ttgaacaaac tagccctgat tttgtattat tactagggga tagaggagaa
     2461 atgttggcag ctgcgatagc ttgtttgtat cttggaatca aaacagcaca tattcacgga
     2521 ggcgaagtgt ctggtactgt agatgaatca ataagacatg ccataacgaa aatagcatct
     2581 gttcattttg ctgctacgga aaaaagcaaa gagcgtttaa taaaaatggg ggaagattct
     2641 tggagagttt ttcccgtcgg agctcctaga atagatacta ttttaaataa tagattacct
     2701 agttttagag atataaaaga aaaatatcat ctaaaatttg aaaagaaaaa atacgttttg
     2761 caagtatttc atccagttgt aaccgaacta gaaaatatag aaaaacaaat tttagctttg
     2821 atcaattcaa tggaacaaca atctcaacca attatttgca ttttacctaa tagtgatgct
     2881 ggtagcgaaa ttatcagaaa aatgtaccag aaatatttaa aaacggatat tatttatatt
     2941 acgaatttag agccggagga atacctgact atattaaaag agtgcaaatt tatgatcgga
     3001 aattcttctt ctgggataat tgaagctgca tcattcaaaa taccagtaat aaatttagga
     3061 accagacaaa atggacgaga acaatctaaa aatattataa atgcaaatct aaatgaaaat
     3121 gaaattgaaa ctgctttgaa taaaatacaa gatcctcagt ttataaaaag cttgaaaaat
     3181 gttaagaaca tctacggtga cggcaacagt tctagaagaa taacaaaaac attgaatcaa
     3241 atattgaatg atggggaaga tattaagtgg attcaaaaac aaatagctta ttaaaatata
     3301 ctagtgatcc atacattatt attggggctg gcggacacgc aaaagtcatt attgaaacct
     3361 taagattaga aaataagtta atatatggat tttttgatga taagcaaaat aaaatgcaag
     3421 atctgaaata tcttgggaaa ataaacgaat tgaatagctg ggcggatagc aaaaaaaaaa
     3481 tctataaatt tattgtagct attggtgact gtgtagtaag aaaaaagatt ataaaaaaat
     3541 tgaatatgcc aagtgagcaa tatggaatag ctgttcatcc aagtgctata gtggcaaaag
     3601 aaatttcaat tggttatgga actgttattt ttgcgaatgc tgtaattaac ccagatgctg
     3661 taattggaga gcatgctata ataaacacag gtagcattgt tgagcatgat tgtagaatta
     3721 ataactatgt tcatttatct ccaggtgtat gcttagcggg tggagtacat gtaggtgtag
     3781 gaactcaaat aggaattggt tctcaatgta tccagatgaa gaaaattgga tcttggtgta
     3841 tgataggcgc agggagcact attgttaagg atattccctc acattcctta gcttatggca
     3901 atccagctaa aattaagaaa gaaggaatta attttgaatt ctagaatttt attatcaagt
     3961 cctcatatgg gaggaacaga agaaaaatat gttgctaagg cttttaaaga taattggata
     4021 gcgccattag gtgaaaatgt ggataaattt gaagaaagta ttacaaaata tactggttct
     4081 aagggcggag cttctgcgtt aagttcaggt acagctgcca tacatcttgc cttaagactg
     4141 cttaatgttg gaaaaaacga tattgtcttt gctccttcat ttacttttat agctacagta
     4201 aatcctattt tatatcaagg ggctgtacca gtgttcattg actcagaacc taatacatgg
     4261 aatatgagcc ctgttgcact agagagcgca ttagaagaag ctgaaagaaa caaccaatta
     4321 cctaaggcaa tcatcgtagt gaatttatat ggtcaaatgg ctgattatga acgaatttta
     4381 gctattgcaa accaatttaa tgttccagtg atagaagatg cagcggaatc gttaggttct
     4441 acttataagg gaatttcgtc aggcttattt gggacaattg ggatctattc atttaacggt
     4501 aataagatca tcacaacctc aggtggagga gctctagtgt ctagtgataa aaaatatgtt
     4561 gagcattcaa gatttttagc aacacaagca agagatcaag caccgtatta tcaacatagc
     4621 gaaataggtt ataattaccg tctaagcaat atttctgccg gtatcggacg tggacaaatg
     4681 gaagtattga atgatagagt agctaaacga agagaaattt tcaatcgata taaggaagct
     4741 ttttctggaa ttgatagaat tgaaatgatg ccagaagtgg atggcatggt gccaaatcgt
     4801 tggttgtcta ctttaacgat caatgattat aattctattg atcaagtagt taacgtaata
     4861 aataaactaa atgaaaaaaa cattgaaaca agagctttgt ggaaaccact acatttgcaa
     4921 ccagtatttc aaggggtaaa aatgtattac catgataata atcttagtgt gtcagaaaag
     4981 ttatttaata gcggcttatg cttaccttct ggaagtaata tgacagatag tgaacaagaa
     5041 tttgttattg atgagtttaa aaaaatattc aagtaggtgt gatattttat gaacatagga
     5101 attattggtt taggttccat ggggaaaaga agacttagac tcattcaaga acactttaat
     5161 gatattttac tatgtggtgt tgatactaat gaggcgagac gaaaggaagt tgaaaaggaa
     5221 tttggaatac caacttataa tagtctaaca gaggcaaaaa atttgtttga aataaattca
     5281 gtttttgttt gtacatcccc tataacccat gaatttatta taaaagaggc tttaaattta
     5341 gattgtaata tctttacgga aatcaattta ttaaatgaat attatgatga aataatcgaa
     5401 gtagctaaaa agaaagatag attactttat ctatcttcta catttttgaa gagaaaagaa
     5461 attcaatata ttaagtctaa agtgacgcat aataaaaaaa tttcttatca ataccatgta
     5521 ggacagtatt tacccgactg gcatccttgg gaagattatc gcaatttttt tgtttcaaac
     5581 aaaaaaacta atgggtgtag agaaatattc gctattgaat taccttggat tatagataca
     5641 tttgggaaag ttaaatcgtt tactgtaatg acccagaaat tatccaatct tgatattgat
     5701 tattcggaca gtttcactct tattattgag catgaaactg gtatagttgg aactttaagt
     5761 gtagatgttg tttcaagagt agctaaaaga aatttaacta taattggtga aaagatttta
     5821 atagaatggg aaggtaaccc ggattctcta ttttcatgga atgaagaaac ttctagtatg
     5881 acagatattc aattgtacga tgaggttatg catgataata attattcaca tactattatt
     5941 gaagatgcat atttagagga gattaaagaa tttttcacgc ttttggaaaa gaaaatggaa
     6001 ccccaatata cttttgaaaa agataagtat attattaact taattaacga cattgaggta
     6061 aattaatgat gaaagtaatt tttttt
//
LOCUS       DADVXE010000111         6029 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.114, whole genome shotgun sequence.
ACCESSION   DADVXE010000111 DADVXE010000000
VERSION     DADVXE010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6029
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.114"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(68..370)
                     /locus_tag="KB913_002704"
     CDS             complement(68..370)
                     /locus_tag="KB913_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6820998.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(590..956)
                     /gene="ssrA"
                     /locus_tag="KB913_002705"
     tmRNA           complement(590..956)
                     /gene="ssrA"
                     /locus_tag="KB913_002705"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1127..1900)
                     /locus_tag="KB913_002706"
     CDS             complement(1127..1900)
                     /locus_tag="KB913_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6820999.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2044..2394
                     /locus_tag="KB913_002707"
     CDS             2044..2394
                     /locus_tag="KB913_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBB6821000.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2375..3091
                     /locus_tag="KB913_002708"
     CDS             2375..3091
                     /locus_tag="KB913_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6821001.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3091..4539
                     /locus_tag="KB913_002709"
     CDS             3091..4539
                     /locus_tag="KB913_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6821002.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4610..5119)
                     /locus_tag="KB913_002710"
     CDS             complement(4610..5119)
                     /locus_tag="KB913_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821003.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5109..5834)
                     /locus_tag="KB913_002711"
     CDS             complement(5109..5834)
                     /locus_tag="KB913_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821004.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         2052 a         1050 c         1170 g         1757 t
ORIGIN      
        1 aaaaatatcc cttttataag tatggtgata aaatccgttc cgggctacct tttttaggta
       61 gcctacttta atctttatac ctttctggat caacgaaagt atacttcaaa tagtcataac
      121 gccgatgatc gctccgtgcg tctggcacat cagtcacgat atcaaacaaa aaatacacat
      181 ctttcttcat tctggttttt gttgccggaa ttttaaagta gttcttatta gagtaataga
      241 gattgattaa taagctatct tcgattgcta aaaagaaaac ttctgaatcc cacaccttat
      301 aaaaatcttt gacaaatcta ttcgaaggat caaatttaaa ccataattgt gtttttcctt
      361 ccatcaacat aatgttcacc tcaaaaagag tatacgaact aatgttcttt ttgtaaagta
      421 ggaatatcat tgataatatg gatggaacat atatattaaa aagtgttctt tttgaatgct
      481 attttgaatg ccattttcat tcatttaacg aaaatctgcg aaaataaaaa atgctcaaac
      541 ccttataaaa taaggattta agcatctagc gaaatctgct gaaatctcac aatggagacg
      601 gcgggagtcg aacccgcgtc caaacacatc gccacttaaa aatctacgtt catagtcaac
      661 tcatttaagg attcacttta cagcttgccg agtgacaggc attctgtatc gctagtctga
      721 tgttctcttt ttcaacttac agacggaaag ttgaaacgta tcccactaaa gttaggaccc
      781 ttactcgagc acatgggcga tgccgagagg atctacgcta actgttttta ggcagctaaa
      841 gcgtaagagt tgttttcgtt tttagcagtt atatttaact gtaacgtttt tacgtagacg
      901 taacctacga aacgcaattc aagctcgact gtgcctgtcg aatccgtaac gtccccgtta
      961 gctaacaagg gttacgtgta tttttcatac aaaattagta tagcatatat tgggataaat
     1021 tcaataaaaa agcgaatcat atcccattat ttatataata actgcccctt tcttaagaaa
     1081 aaataagcga ttttcttaag aaaagaggta gcttcaaaaa aagatcttaa atcagatcaa
     1141 aatacttcaa tgcgtggaca attccgcctt ctgtattttt ctttgtgata aaggtagaaa
     1201 gttcttttaa tccgtcatag gcgttgccca tagcgatttt gttgtcgcaa gcttccaaca
     1261 aggcaaaatc attcggacca tcgccaaatc caaaagtagg aactttttcc agctgaagtt
     1321 ctttttgcag acgtttgaca cctgcccctt ttgagattcc tttcttcact gtatcgatcg
     1381 agtaaggacc attccgataa aaagttagct caggaaaatg ttcgtgatag tattcgtcac
     1441 ctgattgaga taagatcagc aacatattta ctgtgttttc tttaaagcct aaaggatcaa
     1501 tttccggaac atctgaatga atgaagtcgt aagcattgat cattgtttgg ctatgaccgg
     1561 tacaccagat tttctgatcg ttatagtaag aaagttcatg accgttcaac tgtacatgat
     1621 catacatttt ttgacattct tctgaagaaa atgtttgaga atagatttct tcgccgtcta
     1681 ctcgaatgaa agaaccattc atggtgaccg cagaagtaat gcccgcatct tccatgatag
     1741 agtggatttc tgcttctgta cgtcctgtag cgatgacggg gagaacattg ttttctttta
     1801 atgcgttcat agcttttgcc acttcgggtg tgatttttga tttcgcatct agtaatgttc
     1861 catcaagatc aaagaaagtg attgcacgat aatttgacac aaataaaact ccttttttat
     1921 tggaataagt ttatcttaac aaagaatgaa caaaagacaa acctttcgtg aagaattcct
     1981 gaacatattg gttcagtcaa caatttagag tatactataa gaagagaatt taggagggaa
     2041 agaatgattt ttttcagtat tggtatctta ttcttaataa ttggcagtct ttttcggatt
     2101 ctgccctcaa aaggaaatct gcctttttat gggtatcatt cgcctcttgc cgcaaaaaca
     2161 gacgctcatt ggcggctggc tcaaaagaca agcggaaact ggttttttct tatgggctta
     2221 ctgatggcat tgatcggcta ttatttaaag acatctgggc atacgaatta ttttctgatt
     2281 gaaatgcttc tgctagtatt tccaattatg cctattttta ttatgacaga aaagaaatta
     2341 cagaaatatg acctggaaac tggagggaac gataatgaat attttaatga ttgaagataa
     2401 tcaatctgtt tctgaaatga tgcagatgtt tttcttaaat gaaggttggg aagcaacttt
     2461 caagtatgat ggaaaagaag ggctcgatgc ctttttagaa aacccacaac attgggatat
     2521 gattacacta gacctgaatt tgcccacact ggacggtatg ctagtaggaa gagagatccg
     2581 caaagtttca agtactgtgc cgattatcat gctgacagct agagattctg aaagcgatca
     2641 ggtgatcggc ttagagatgg gggcagatga ttatgtcaca aaacctttca gtcctctgac
     2701 gcttattgct cgaatgaaag ctttgcatcg ccgtagtgag ttggcagaag caagagaaga
     2761 agcagtagtt tcagatgatc attttgatat cgagactagt catttcaaga tgaatacgaa
     2821 aacacgagaa gcgtatctgg acaaccggcc aattgaagga ctgacgccta aagagttcga
     2881 tctattgttt actttagcaa aaaaaccacg tcaagtattc tctcgggagc agttgcttga
     2941 attagtctgg gattatcagt actttggtga tgaacggaca gtggacgccc atatcaagaa
     3001 attacgacaa aaaatcgaaa aggtcggacc acaagtcatc caaactgttt ggggagtcgg
     3061 ctacaaattc gatgattctg gtgttgccta atgcgttatt tgtatcagca actcttagct
     3121 ttctgcggaa tggtcgcgtt gatcttattg atcgttggag tttcttttac acaactgaca
     3181 aaacaaacga ttgaagaaaa caattaccag caactgtttg gatatgctga atcagttgaa
     3241 aagacaacgc aaacctatgc cgatacgctc ccgcagttta gtcaagatca ggcgtttcaa
     3301 aatgcattgc tgctgacaga gcaagtactg acagaacaaa atgtgaactt tatatttatc
     3361 gataaaaacg aacgtgtcat ttatccgact aatacagctt tactgaattt taccttaaca
     3421 gctgatcaat ggaaaaatct gaggaatgga cgtcaagaaa aattcacatc gaataaaaat
     3481 attttaggac aagcacaggc gacctcttac gcacttgtgc catttaattt gaatcatgaa
     3541 ttctatggag cacttgtagt tagtcaacct gcgcgaaata tcgataacag cgttcgtcca
     3601 attacactga acctgttcaa aggatttatt ttttccagta tcgttgcagt tattgccagc
     3661 tatgcttttg cagcattcca agttaagcgt atcaatcggt taaggaatgc gacgaaagaa
     3721 gtgacgaatg gtaattttga tgtacagctc cccgtacatg acaaagatga atttgatgag
     3781 ttagcagatg atttcaataa aatgacgaat tcattgaaag aatctcaagc agaaattgaa
     3841 gaacaagaaa atcgtcgaag acaatttatg gcagatgctt ctcacgagat gagaacacct
     3901 cttacgacaa tcaacggact tctggaaggg ttagaataca atgcaatccc tgaaaatcag
     3961 cgagaaaacg cgattaaatt gatgaaaaat gaaacagagc gtctgatccg tttggtgaat
     4021 gaaaacttgg attatgaaaa aatccgtacg aatcaaatca gtatggtcat taaaaaattc
     4081 aatggaacag aaacattgaa aaatattgtt gcacagttag aagctaaagc agaagcagca
     4141 ggagatacat tgacattgaa agccgttgat gatattgatg tttacgctga ttatgaccga
     4201 tttgtccaaa tcatggtcaa tattattcaa aacgcgatac agtttactga aaacggccaa
     4261 atcacgatta ctttagaaaa aggctatctt gaaacgatca tcacgattga agatacggga
     4321 attggaatgt ctgaacaaca aatgaaaagt atctgggatc gttattataa agtagatcct
     4381 tcaagaaaaa atacaaaata tggtgaatca ggattaggtt taccaatcgt gcagcaactt
     4441 gtacgcttgc ataaaggaaa attagaagta gaaagcgaac taggaaaagg aacaaaattc
     4501 gctgttcgtt tgcctgacgt agaaatcaaa aaagagtaaa aaacaagcgg tataaaagat
     4561 catgaatcga tcttctatac cgcttgtttt ttactataaa atgattgatt tagcccgcgg
     4621 gctctaaacg atcaatataa ggactttgag caatagtagc atcatgagta aagagtaaga
     4681 taccttgatt ttcttcatga gctaaataag aaagcaagtg gagtagctct tggatctcca
     4741 atacactaag ttcatcaaat gtatcttcaa taacaatatt gtttcgcttg gaaagcaagg
     4801 catgaagtaa ttgcagcttt actttttcaa aagacgtcaa ctcagctgcc gcacaattaa
     4861 gcaaggaagg agagatatca agtttttctt gataggccaa acgatcttgt ttgatttctt
     4921 tttccggtac atccaacagg acatggtctt taagattcag ataaggaaac atcggccaat
     4981 ttttttggat gatcgcaaaa ttatccagtt ttgcaacaag aacctctttt ttcaagtgct
     5041 ccaatatttt atgctgtttt tcgagaggac acaaaataac ggtcaagtgt tcagcatgaa
     5101 tcaaatattc aggtttcatt acgtccaggc ctcctacttt gcaaatgatg gataaaaaaa
     5161 gtgaaaggga atagactaag aatgagacag catccactga gcccaataag agtttgggca
     5221 aatcccttaa gtatatctgt gaaaaaaaga tcattttgga aatcgatggt aaaaaaagtc
     5281 tgttgatcca tcggaattgt aagtccgctt accgaagtca agatatcacg gatatctggc
     5341 agttcagtag tctttaagac aagaaaattg atcctttgaa gaagcgcttc ataaactgac
     5401 tggaagctta cgatccacaa taaaaccaag atacaacaaa gaaagagagg aaagaacagc
     5461 tgccagaaaa taaaaaggaa taatttggtt ttagaaagac cagtcaggtg ccaattgatc
     5521 aattcctgct tgttttgcct gactgaatag taaaagaaaa agataaaaag gaaggcaaat
     5581 agaaaaaata aactgaatat gccttttata taaaatcggc tagctaattc taaagccgga
     5641 agaagctctg tagatgcaga agcgccaata aatgaaagcc gatcttggac ttgattggct
     5701 aaagccgatt gcaaatggta aagagtcagg catgctatca ataaaaaagc agaaaagctt
     5761 gaaaataaac aatagagtat tgtctgcttt ttgtaataaa ttaatcgagc agtagcatag
     5821 cggattattt tcatactttt cacctctata aaaagtatag aaaatgaata tgaataaagt
     5881 atgaaattcc tttagtgaaa tcacgaatta aaaccagaaa atattttgta aaaagcaaga
     5941 ggttgtgaag aagctgccct attctattac cgtagatgca agcttttgaa cactgtttat
     6001 tcgaaaagag gagcagcgac aataatttt
//
LOCUS       DADVXE010000112         6017 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.115, whole genome shotgun sequence.
ACCESSION   DADVXE010000112 DADVXE010000000
VERSION     DADVXE010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.115"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            33..1372
                     /locus_tag="KB913_002712"
     CDS             join(33..474,474..1372)
                     /locus_tag="KB913_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBB6821005.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
     gene            1492..1665
                     /locus_tag="KB913_002713"
     CDS             1492..1665
                     /locus_tag="KB913_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821006.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
     gene            complement(1731..2339)
                     /locus_tag="KB913_002714"
     CDS             complement(1731..2339)
                     /locus_tag="KB913_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBB6821007.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(2345..3373)
                     /gene="vanB"
                     /locus_tag="KB913_002715"
     CDS             complement(2345..3373)
                     /gene="vanB"
                     /locus_tag="KB913_002715"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBB6821008.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            complement(3366..4337)
                     /locus_tag="KB913_002716"
     CDS             complement(3366..4337)
                     /locus_tag="KB913_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBB6821009.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            complement(4334..5041)
                     /locus_tag="KB913_002717"
     CDS             complement(4334..5041)
                     /locus_tag="KB913_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBB6821010.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            complement(5059..5865)
                     /locus_tag="KB913_002718"
     CDS             complement(5059..5865)
                     /locus_tag="KB913_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HBB6821011.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
BASE COUNT         1698 a         1411 c         1217 g         1691 t
ORIGIN      
        1 gactagaaat ctaattaaaa ggggtgcttt ttttgcggaa atatacattt gtttttaaga
       61 aaaaagtagt ttcagactat ttaaataacg aaggcggcta caaatatctt gcacataaat
      121 atcaaataaa tcgtacactg gttagacatt gggtaaggat ttataactat catggttggg
      181 aaggcttggt tggaggtggc aaaagctaca ctacaaaatt taaacttgat gttatagaat
      241 atatggaaac aaatggtctt tctatccaag aaactgctaa aaaatttaat atcggttcaa
      301 atagaactct aagtaaatgg atagagcaat atgaagaagg cggtgcttct tcacttgaga
      361 gccaaaaaag gggcagaaaa attagtatga attccaagct aaacattcct aaaaaactta
      421 aagatgagtc tcttgaagaa gaagttattc gtttaagagc agagaacgca tatttaaaaa
      481 agttagaaac cttgattcaa gaacaagatt tgagcaagaa gaaatcaagg ttaaaacaat
      541 ccttcagctc aaaaaagaat ttaaattgaa tctattactt tcaattgcac aattagcgaa
      601 gtcaacttat tattactggg taaaaaaatt agataagcca gataaatata gcaagataaa
      661 gcaagaaatt acagcgattg taaaagaatc aagaaactct tatggttatc gtagagtcac
      721 tttagcgtta aagatgaaag gatatacaat caatcataaa acagttagaa aattaatgtc
      781 ccaaatggga cttacctgtc aaatccgaat aaagcgatat aaatcttata aaggaacagt
      841 aggaaaaatt gccaagaatg tgttaaaacg aaatttttca gtagatacac ccaataaaaa
      901 atgggtgaca gacgtcactg aattcaagat aaaaggaaga aaaatctatc tatctcctat
      961 acttgattta tttaacggag aaataattag ttatagtata tcaactagtc caacatataa
     1021 actgattgaa gaaatgcttc aacaagcaat taaaaaaaag ggaactgagg gttcactgat
     1081 tctacattca gatcaaggat ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga
     1141 gaataacatt attcaaagca tgtctagaaa aggaaattgc ttagataatt ctgtaataga
     1201 aaattttttt ggtgtgctta aatcagagtt tttttatcga gaaaaattcc gatcaattga
     1261 gatatttcaa agtaaattaa atgagtatat taggtggtat aataacaaaa ggataaaact
     1321 aaagttaaat ggactatctc cagtagaata tcggaaacag tccattaaat agttcaactt
     1381 ttggggttca gttcatggag gggcaaggct ttttttgagt ggtggaagtg gattagagca
     1441 tggcaatagc aaaacagcat agcggcatcc tcctatgggc cgccacacct tttgctgcca
     1501 gaaaagaacg gcggccttga tttctcaaaa ccgccgccag caaaatacaa aatgggcgtg
     1561 ggaaaggtct gcccaacagc ggtttttttc ttttctgccg ctgggcagat tgaatactat
     1621 aatttgcaat gtattacaaa agatgcttta accactttcc agtaaaagat tgtccatgac
     1681 cagcatagat tttatcaaat ccaaaatctg atacaaaacc aatactttca ttatgaaacg
     1741 gcaaaattaa aataggtatc ggggtatggc tcatcaatca acttatagtg ccaccattca
     1801 aagcgataag actgaaatcc gctgctttcc atgattttac gcaagcatct tcgattttgt
     1861 gcctctgcat cccctatccc ttttgctgta tgatgcgacc gttcgtccat aaaatcgaag
     1921 ttacttccca ttgaaacaag ttcccctgta tccaggtggt agagcgtaag atcaattgcg
     1981 cttccacggc tatggctgga ttgtgaggcc acataaccct ttgtaatcaa ctcggctcgc
     2041 tctatattgg ggtaaaattt ttcttttgtg agattgtcct ccggttgcgc tgcccaacgc
     2101 aggaagcagt ccaccgcagt tcttggccga tatccatccc ataaaagcaa gccatagcca
     2161 agcgcagccg catggatttg tgcctcgcgc agagcaaacg ccacggcctt tgtgccgatg
     2221 atgcgattca cctcataccc atccaccggt tttcctgtga agttatccca tgtggcgtac
     2281 ttggcatccc aacggacgcc atgcaacatt tcatctaaaa acaaaaaacc attttccata
     2341 cttatcacct ctttaacgcc aatgtaatca ggctgtcaat cagtgcagga agcgtgattc
     2401 ctgcggcggc catcatacgt gggtagcggc tgtacgatgt aaaaccgggc agggtattga
     2461 cctcatttag aacgatgccg ccatcctcct gcaaaaaaag atcaacacgg gcaagccctc
     2521 tgcatccaag cacccgatat actttctttg ccgtttcctg cacccgattt cgttcctcga
     2581 ccggaatgtc tgcgggaact gtaatcatcg cattttctga gcctttttcc ggctcgtttt
     2641 cctgatggat gcggaagata ccgtggctca gccggatttg atccacttcg ccgacaatca
     2701 aatcatcctc gttccccatg accgcacacc cgacctcaca gcccgaaatc gcttgctcaa
     2761 ttaagatttt tccatcatat tgtcctgccg cttctatcgc agcgttaagt tcttccgtac
     2821 cgtttacttt ggttacgcca aaggacgaac ctgaccgtgc cggcttcaca aagacagggt
     2881 aggtaagcgc acccgcctcc ggcttgtcac ctttatcaat catttgaaat tcgggaacgg
     2941 cgatgcccgc attttttgta agaatgtagg ccagtgattt gtccatgcaa gctgcggagc
     3001 tttgaatatc acagcccaca taggggatac cagacaatac aaacagcccc tgtatcgcac
     3061 catcctcccc gcatttgcca tgcaaaaccg ggaaagccac atcaatacgc cgtgtttcgt
     3121 attcgctttc tttcatgaca agcagcccat gcgttttcct atccggggag agtatggcgg
     3181 ggagactgtc ggcttcccat tccgtacatg gcttcttgca tagcttccat acaccgtttt
     3241 ttgtaattcc gatgtagtgc ggatcgaatt tttccgtatc aatgttcgca gcaatttcta
     3301 ttgcggcttt taccgacaca tcatgttcct ccgagcaacc gccgaagatg attgcgactt
     3361 ttattctatt catgctgtaa actcctttca aaattgagac aattcctgat tgttttttct
     3421 gtagtatcct gcagcacacg ctcagtgtag tacgccgtat ggggtgtgat gatcacattc
     3481 ggcatcctta aaagctgcga caaaaaggga tggtcaagca ctttctgcga gcaatcggta
     3541 taaacaaact gatcctcgcc ctccaacaca tccagtgccg caccacccag ctttccgctt
     3601 tccaacgcct ccaccagcgc cccggtatcg acaagcgctc cgcgcccggt gttgattaaa
     3661 aatgcgcctt gcttcatctc tccaatttgc ttctgaccga tcagatggcg ggtatccgca
     3721 caaagcggca catggagcgt aacaatatcg ctgtttttta gaagctcatc aagctggaca
     3781 taatctgcat ccatttttcg gctgttatca taggccagca catggcatcc aaatccccgc
     3841 agccttttga cgaccgcttg cccgatatgg ccggttccaa taactcccac agtcatatcc
     3901 cccagttctt tcccccggat acgatccaat ctgaaatctt gttgcgccac ggcgtgcatg
     3961 gtgggttttg caccccgtat ggccatcagc atcagcatca aagcataatc cgcaacgctg
     4021 tccggcgaat acgcaaccgt gccaaccgag attcccattc tctcggcggc agtcgtatca
     4081 atgtgatcgc agccgatgct gcgggtagaa atgtatttta ccccgacctt tctcagcgca
     4141 agaattgtcg cctcggaaac ctcggactta tggcttacgc taacgcattg attgccagcg
     4201 gccaattttg cgttgtctgc cgatatcgca tcgctaatca gcgtagggat aatatgaaaa
     4261 tccggcgata aagcgcggaa agcatttgcc tcatcctgtt cgcatccaaa aacagtaatg
     4321 cccacacttt ttctcattgg ttctcctcct gaatatccac actttccggg aggggataac
     4381 agattttgca tttgtttgta taaagcagct tgcaatctat tatttccccg gtacctaagg
     4441 caacttgcat ccgtttaacc tgggcatatt cataaatccc gccactttca cggacatact
     4501 ggatactgcc atttgtaatt ttgtataatg cttggggctc tttgtcggcg aacacctgac
     4561 cgatgatttt ctcatcatct aaggtcaccc atatttggta ggtgcagtcg gtatcgtttc
     4621 gcacttttaa atcaatccag ccctctgaaa tggttgcatc caccccttta atctcgtcac
     4681 tgtttggctc tggaaactcc tttacttcgt gacctctgcg ctggataatt gtcaatggcg
     4741 tatgcaggaa caaccagaaa gaaaaggttt cccccggtct tatcaataag ccgtttaagg
     4801 tctttgctgc cagctttaag ttgaacacct tgttttcctg gtatatcatg tcaaatccgg
     4861 tattgtggtt gtataatgcg caatccgttt caaagagcaa atgggaaagc gatttttccc
     4921 ctatcgtctg cgcatagcga cagccgtcaa atctcattcc cgcataaaag cacatttttc
     4981 tctgcgcccg tctcattgga agcaggaacg ggaaacgctg tgtcaatctt tttctgtcca
     5041 taacataaca tccttttctc atttttctgg ttttaaatat tcctcaaggc aaaccccttg
     5101 gttgtacatc tctgtggcag cttcgatgcc aacatatcgg taatgccacg gctcgttgct
     5161 cacaccggtt atctctgtct tgtctggtgg gtagcgacga ataaaaccaa aacgatagct
     5221 gttttcatcc agccatctat aaacctcgtt gcctgttgaa tgaattccgt ccgcattgat
     5281 atccacagca agaccaagct gatgctcgct cgttcccggc acggccaccc aagtttctgc
     5341 ttccgcttta gcctgtgcag aggtgtagcc tttcgcctta tattcggcaa ttttttcatc
     5401 cataatttct tgctgttttt ctgttgttcg gtatccggat gcgacaatcg ggtaaactcc
     5461 atcagttctt gcggcatcaa acaaatcttg aagataggga gaaatccgaa tatctatccg
     5521 ctcaccattt gatagttgct caagctccac atcgtactgt gcggggatgg ggttctgcct
     5581 gttcactaaa atcaggctcc attcctgttc atctccctgt tctttggcgg tggcaagagc
     5641 gttttcctcc aaattctcca ctacgtcagt gctgctgcct gtatgagttg cagggatggg
     5701 cggtatctgt gttgcctcca atacggaagc cagtctccac cccaaaaaca gcgtgcagac
     5761 tgtgaacgaa ataatgaacg cacatagaaa agcccgcttt tccacggatt gtttcatatg
     5821 ccgtttgtga tgatccgcat tggaatgata gttgcttttt tccatttgat cgaatgcctc
     5881 ctttgcaata aaactacgat ttgtggctgg tacgattgtt attatggcaa gcgcatctgt
     5941 actttccctg tagccagtct gtagttttcc tgtagcagca aaaaaagacc ggcagggtta
     6001 tacctgtcgg tcaaaat
//
LOCUS       DADVXE010000113         5947 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.116, whole genome shotgun sequence.
ACCESSION   DADVXE010000113 DADVXE010000000
VERSION     DADVXE010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.116"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            59..415
                     /locus_tag="KB913_002719"
     CDS             59..415
                     /locus_tag="KB913_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBB6821012.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
     gene            405..671
                     /locus_tag="KB913_002720"
     CDS             405..671
                     /locus_tag="KB913_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6821013.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            830..1831
                     /locus_tag="KB913_002721"
     CDS             830..1831
                     /locus_tag="KB913_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HBB6821014.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(2201..2815)
                     /locus_tag="KB913_002722"
                     /pseudo
     CDS             complement(2201..2815)
                     /locus_tag="KB913_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            3055..3300
                     /locus_tag="KB913_002723"
     CDS             3055..3300
                     /locus_tag="KB913_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821015.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            3398..3619
                     /locus_tag="KB913_002724"
     CDS             3398..3619
                     /locus_tag="KB913_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821016.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            3941..4621
                     /locus_tag="KB913_002725"
                     /pseudo
     CDS             3941..4621
                     /locus_tag="KB913_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            4683..5300
                     /locus_tag="KB913_002726"
     CDS             4683..5300
                     /locus_tag="KB913_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821017.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
BASE COUNT         2190 a          816 c         1067 g         1874 t
ORIGIN      
        1 aattcgaatt tttatgttat atactataat ataaaatcaa tatatgatat aattgggtat
       61 ggaaaaaata tcttttgaaa catttaaaag acctaatggt catgatgaat ttttagaatg
      121 gttggaaaca ttaccaaaaa aagatagtgc gaagctttta cgtacaatag aagaaacaga
      181 aaagaatggg atgctagtag ctcaacggtt gaaatgggtg aaaaaattag acactaattt
      241 gtacgaatta agaagtaagg taggatcaaa catccaaaga gctatctatt tccatgtggt
      301 caatggaagg tatgtcatta cccatggatt tactaaaaaa acggagaaaa caccaataag
      361 tgaacttaaa catgcaaaag aacttagaga ggagtggttc acaaatgatg attaaaaaat
      421 tgattgaaga aaagcaaaaa gacaaagatt ttgcagaagc atatgaccgt gaaggaagaa
      481 aactcgaaac tgcggttgct ctttatcatg cacgggagga agcaggccta actcaagcgg
      541 agcttgcaca aaaagcacat acaactcaat ctactattgc tcgaattgag agaggggata
      601 acgtatcttt cgataaactt gatgatatcg ctagggcatt aggcaaaaag ctggtagtag
      661 aatttgctta aaagcgagtt gaaaatatac ctgtaatagg ctcctaacta atcaattagt
      721 ttagtgggcc tttttgtact aaatagataa aagttgtcct atagtgtaaa agtcaataaa
      781 ttttatacaa aaattacttt aaagagacat aaagagaaag gtacaataaa tgaaaaccat
      841 aaatctaata aaagtattta tagcatcacc aggtgatata gcagcaaaga ggaatgaagt
      901 agaagaaacc atatatagat ggaatataga aaatacagat aatacaaaag taattttgat
      961 gccaattcga tgggaaacga atgcgattcc tacttatata aataatagct ctgggcaaag
     1021 tgttattaat aaacaaattg tagaaaatag tgatatatta ttagcgattt ttggccataa
     1081 gttgggttct ccagttgata attatagatc gggaactata gcagaaattg attactttta
     1141 taaaaatagc aaaggcgagg taggggtttt tttcttagat gaaccagttc cacaagtttt
     1201 ggctgaagag tatatagaag ttaagaagta cagggactct ttagaagata agggttttta
     1261 tggaacatat agcaaagaca atatcagaag gtttctcaca aaaaaagtga attatttaat
     1321 tgagaaagca caaaataatt tagaatcaaa acgctttgat ttagattcta tttcttacaa
     1381 gacaccttca gtaattaaca aaaaagttac cggaactgat aaagattttg atgacaactt
     1441 agatattttt gatccaatag aatttgacaa tgatgaaaga ttgctgctaa tatatgcgtt
     1501 tatggatgaa aattctatct tttcaactga taattcaact tatagaaaag tagttcaatg
     1561 ggaaagtgat aacaatttaa ggagttactt gagtgataga gtatttgatg tactagaaaa
     1621 attaagtaaa tcgggaattt taaaggaaga atacgattct tcttttgatg agtatccatc
     1681 acgctatatt ttgatttcag aggactataa gaaatttaaa aggtattttt taaaaaatga
     1741 aaaaaagata tctgttatta tggagaaata caaagctcca atacaggctg atccattttc
     1801 caatttggat gaatcagatt taccgtttta aattttaaat agataatttc attttttagt
     1861 agcagaggta taaacttttt taatgtttga attgaaaaga aatgctaata ggtcgacttt
     1921 atgtttctct tgtgcaatcg taaatgcggg ggaccataaa attgatctat tatcgagtgt
     1981 gtataaaata aaattcaaat cttattagtt tacataagat acattatact aagttgtcaa
     2041 tgttaaatgc ctttaaataa ggacgattta tgcatcaatt atatttatgt taactaaatt
     2101 ctttttaaca taaatgtaat caacttagct agatgaatct aaaatgattg tctgtattga
     2161 tgacaaagct aattaataat tacgtgattc aaaaaagaaa tcatacaatt agttggtcga
     2221 tttctttttt tattcggtaa attgtttgcc tagtcacatt gtagtctgtt gcaatctttg
     2281 agatagcaac cccattctca agatcctgaa cgatactcct atagacaagg cgacgttgag
     2341 gatctttggt gtctgcactg tataacttag gacgaccttt atagacgccg tttgctttag
     2401 cgattttaat tccttgtgcc tggcgtcgtt tcgattcagt acgttcttgt tcagcaatca
     2461 tggctgagat ttaaatgatt aagtctttga tgaatttatc taggagagga tttccaattg
     2521 cttcagccat gatcggtaaa ctggtgataa taagtcgcac attcttcttc tttagataat
     2581 tcactgaatc gataatctcg tcataattgc gtccaagtcg atcaatggct tctacaataa
     2641 aaatatcttg ctctctgaca aaatctaaag cttcctggaa aatcggccga tgactaatcg
     2701 tcgctccaga ttgtttttcg ataaaaattt tttcagcgcc aaactttttc atttcttcaa
     2761 tttgacgttg ttcattttga tcgatggatg aaactctaat ataagcaatt ttcaaattta
     2821 ttccctactt ttctataacg tttataatac accctaatca tacgttagaa ctctaaattt
     2881 ttcaatgtta tatttttgtc tatttagggt aaactctaaa tagacaaacg gtttttgaat
     2941 tctaaaagtt aaatagttta taatagaaga aaaagaatgg ggtgacgatt tcttagattg
     3001 aaaaggaaag ataaatatta tagattatta cttttgacag ctgaagcagg atggatggat
     3061 tttccagaag ttgtaaaaga agttcaagag ataggtgcaa ctatttctga tagccgctcc
     3121 tctcctatga actatcagga tgcccatgga attaaaataa ttgatcaaga gagaaatgtc
     3181 agaaaataca caacaataaa tgagtgtgta attaatgaaa atctttgtag ggcaccgata
     3241 acgaaacaca ttaagaatag aagcaaagca aaagacggaa gaacttttac taccttctaa
     3301 gtttttttca tatttgtttg ctatacttag atctaaggaa ttagactttc gctgcccatt
     3361 atttaagttt gaggtagcgt cttgcgaggg atcaataatg gaagaagaaa aaatatttga
     3421 aaaacgctgg gaattggctt cagttgaaca aagagcaagg taccataatc taatgtcctc
     3481 ttaccgtaat attgattgga cttacaaaga aaagaagtac ttgctttggt tatgtcagtt
     3541 agatgtaaat acctttgaaa catttgaagt gattctagat aagattaaaa acagcaatga
     3601 aaaaagagct gatctataat ggttcgctct ttttatttta ttaactcttt ggttactata
     3661 tgtaaaatac agcttcatat tacaataaat ttcaggatac aaatttattt aagcatatat
     3721 aaatataatt gaaataggac ataaatatat gagtatgaga aaggtgattc catgtttaat
     3781 aaatgggcaa accacccaat gaactcgaga ggtagagata atttgaagga gacggacaag
     3841 ttctgggaag aagtatatag taaaaacggt tctgttgcaa agttttccaa aaaatctatt
     3901 ttagtgtaaa attgagaaaa aagacagaga ggacagagta atgaatcatt ttaaaggcaa
     3961 acaattcaaa aaagacgtca ttattgtcgc tgttggttac tacctgcgtt acaatctaag
     4021 ctatcgtgaa gttcaggaat tgttatatga tcgtggaata aatgtttgtc atactacgat
     4081 ttatcgttgg gtataagagt acagcaaagt cctctattat ctttggaaga agaaaaatag
     4141 acaatccttc tattcatgga aaatggacga aacctatatc aaaattaagg gacgttggca
     4201 ttatctttat cgtgcaattg atgcggacgg cttaacctta gatatctggt tacgaaagaa
     4261 acgggatacg caagcagcct atgctttctt aaaacgactc cataaacagt ttggtgagcc
     4321 gaaagcaatt gtgaccgata aagcaccttc tcttggctcc gcctttagaa agttacagag
     4381 tgtgggttta tatactaaga cagagcaccg aactgtgaag tatcttaaca atttaataga
     4441 acaagaccat cgacctatta aacgacgaaa taaattttat caaagtctcc gtacagcctc
     4501 ttccacgatt aagggcatgg agaccattcg aggaatatat aaaaagaacc gaagaaatgg
     4561 aacgctcttc ggcttttcgg tgtctactga aatcaaggta ttaatgggaa taacagccta
     4621 agatatttgg agttcagaga gggcgcgttt gattttcaaa cttcgcaaca gaaccgagaa
     4681 ccttgggttt tcaagtgctt tttggttcat taatcttaac catagtgttt ttaaagtgga
     4741 aaacaagcaa caaaaaaagt atgtggagcc ttgtaggaat agttcttatt atttttactg
     4801 tgactgcagc aacagaagca aattattcgc ataaaattca gtcgtataaa ggtcgtttag
     4861 ttatgaccaa aaaagatgtt acacgttata catcctcaag aactggaggc ctatatgact
     4921 atgcaccatt agatgcattg aaatataaag atcatttaaa gaaacatgaa gtaaaagttg
     4981 gtgatcggtg ggagaatgca tctcataaag catataattc caaaatagtc tatacagtag
     5041 aagatgccga tgagcaaaat atcacattac ctgtattcaa ttattgggga acagttgtga
     5101 aagtaaatgg gaaaaagagc actatagaaa atgacaatgg tttagtgtct attaaaggta
     5161 cggggaaaag aactatagtt gaggtttcat ctacgtatcc aactacgatg attctatctt
     5221 tattaattag ttcaataact tttatattct tatttacacg ttatttaata agatgctgcg
     5281 gtgaaatgaa aatagattag atagatatta taaatatgtt gattctattt tcatagcaat
     5341 ggagaaaata cattagcaat atataaaaga aggtatcaag agtcacagtg aatttattcc
     5401 gaaaagtgaa aagagcaaat ataaaattta atgaaaatat agaactaaat aggaaaacgt
     5461 agacgtaatt ttctacgttt tccttttcat atatattaaa tattacggaa aattatataa
     5521 actaatttag tgttttgttt gtaattccta attttgctcc acttttagat aatttttagg
     5581 tctatttaac tcatcagaca ttctatgctc atttttctcc aaatttgttt caactctttc
     5641 gtacttaatt ttgcgtattt gaaaattctt cttttagagt acttttatta cgatactagt
     5701 atgatatata tctatagcaa acagttaaaa tcttcctaaa ataagcgaat agcattccta
     5761 aaacctataa aatttttaga tgaagcgaca agtggacaat taataaacta cttgaacatg
     5821 aaattatgga tcacctttca aatttagaaa atggaattct tatacttatt gcgcaacatt
     5881 tattgattgc aaaattatgt gacaaaaaaa actagtagaa gaaagaataa tggcttgata
     5941 ataaagt
//
LOCUS       DADVXE010000114         5911 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.117, whole genome shotgun sequence.
ACCESSION   DADVXE010000114 DADVXE010000000
VERSION     DADVXE010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.117"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            129..743
                     /locus_tag="KB913_002727"
     CDS             129..743
                     /locus_tag="KB913_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6821018.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(908..1150)
                     /locus_tag="KB913_002728"
                     /pseudo
     CDS             complement(908..1150)
                     /locus_tag="KB913_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1354..2673)
                     /locus_tag="KB913_002729"
     CDS             complement(1354..2673)
                     /locus_tag="KB913_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HBB6821019.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(2828..3415)
                     /locus_tag="KB913_002730"
                     /pseudo
     CDS             complement(2828..3415)
                     /locus_tag="KB913_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4053..4310)
                     /locus_tag="KB913_002731"
     CDS             complement(4053..4310)
                     /locus_tag="KB913_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBB6821020.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(4303..4572)
                     /locus_tag="KB913_002732"
     CDS             complement(4303..4572)
                     /locus_tag="KB913_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6821021.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(4703..4882)
                     /locus_tag="KB913_002733"
     CDS             complement(4703..4882)
                     /locus_tag="KB913_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821022.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(5263..5829)
                     /locus_tag="KB913_002734"
                     /pseudo
     CDS             complement(5263..5829)
                     /locus_tag="KB913_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1830 a         1085 c          941 g         2055 t
ORIGIN      
        1 cctccatcat tagtttttgt ctatataagg tttaccctaa atagacactg gtataacatt
       61 gaaaaatatg gcttcctcgt gtatgattag ggtgtatttt aaatagttgc agaaagtagg
      121 taaaagtttt gagagttgca tacatacgtg tctcatcgat cgatcaaaat gaacaacgcc
      181 agattgaaga aatgaaaaaa ttcggtgcag agagaatttt catcgagaaa caatctggcg
      241 caacgattac tcatcgacct gttttccaag aagcattaga ttacgtccga gatcaagata
      301 tttttattgt ggaagctatt gatcgacttg gaagaaatta tgacgagatc atcgcttcag
      361 tcaattactt gaagaagaaa aatgtgaagc tgatcattac tagtttaccg atcatggctg
      421 aagcaattgg caatcctctc ctggataaat tcattaagga tctgatcatc caaattttgg
      481 ccatgatcgc tgaacaagaa cggactgaat cgaaacgtcg ccaggcacaa ggaattaaga
      541 tcgcaaaagc aaacggcgtc tacaaagggc ggcccaaatt atacagtgca gacgcaaaag
      601 atccccaacg tcgccttgtt tacaaaagca tcgttgaaga tcttaaaaat ggtgttgcga
      661 ttgctaagat tgctaaagac tacaatgtta cgagacaaac cgtgtataga ataaaaaaag
      721 acagcatggt caatgacaaa tagttgatca tgctgctttt attatcttct catctttaat
      781 ttcctacata taattactat ctataaaatt aagtcttact cagaacagat aaagcataaa
      841 attccaacaa accatttttt acttaactaa ataaagagtc tgttaatata atcttcactt
      901 atttacgtta atcccctact gtatttgttg gttccttatc tatattttct acaaaatcct
      961 tattatcttg tgatttagct tcgtataatt ctttgtatgt cgacacattg gttatactaa
     1021 ttcctatagc tagttcttga gactctactt ttctctctag ctcctttgac aaagtgattt
     1081 gagatttatt tggttccgtt ggagtcaatt ctatagattc ttcataaaaa tctctataca
     1141 taaagctatc cctgaataat tcatagcttt aattctttgg cacattttat tgaaatatgt
     1201 atcactaata tccctatcaa ctgattttga ctaaaaagtt acttcaaaca ttcactgttc
     1261 aaaaatattg aggaataaat tttgggtgta aggcattttg agcatacttc tccctggata
     1321 acttcccagt aaaaaaatcg ttagattgtt ggattagatc cattgactgg ctcgcctcag
     1381 gcgagcaaag accctgtaga attcattctg atacacatga taactagata atttgagata
     1441 gactcgtcta cccgtttgga ctaatttccc agcaactttc agaaacttca atcgaataga
     1501 atgaatggtc attccctttt ggacttcttc aaagccaatc gttcttaaga agttgactaa
     1561 gttgtaagct atcaagctga gcatcattcg gacatgattc tccaaaaagc gaggactgtc
     1621 tgttttgtca aagtaaaagc cagctttcgc ttctttaatg aagttctcca ttgtgccacg
     1681 tttggcatag atagaaaaga tggtatcagg agaaacattt tctgatagat tcgtcacgat
     1741 aaattcatgt cgaaagagta gttcgcccgc ttcacgtgtt gagcgtatac acacgcgacg
     1801 actttgtgac caggattgtg cttgataagt ggtcgagaag tactgaactt ctcgttcttc
     1861 ccacttttga ttatcgccat aaagtactga tttctcagct atttgaccta gtctacgatt
     1921 attcttcagt cgaataacat aatgactctt ttttgattca cacgaatcat acacaccagg
     1981 tgtagcgaac ccgctgtctc cacgaaccaa gatgtcagtg tttggtagag agtgattata
     2041 gtgctctaat aaaggtgtga gaaactcctt tacgcctttt gatgtatatt gatttcctga
     2101 acgtagttca gcttttaaga agtcaccagt caatccgtca aaagctacca atggatggta
     2161 accataggtt tggtagtgtg tattataatt cgtttgttct tggtgaccaa atgtatctga
     2221 atgggtcgaa tctaaatcaa tgattaattc cgtatcatta cggatgaggc gtgctttatc
     2281 gataagttct tggttcaaag cttgaagttc atggatattc tcctcagata gtcgatctaa
     2341 aaatcgggaa agtgaagatt gagaagcgag ttctttccta tctaaaacag ctttaaacac
     2401 aggatcttgt ctcaggagat tagctgcaga atcagctgag taaccagcaa ttaattgcat
     2461 aatgaactgc tcaagtatgg ataagttgtc atgagtaaaa tacgctcgtt cgtcttcaat
     2521 gtgaatgtgt tgcttagcca gttcagaaaa accaaagatg ttcatcagct ctttcactag
     2581 gacgagaccc gaatcactcg ataattgacc acctgtatga gaaatagtga tatttgaatt
     2641 gaattttact tggtttttgt gtaagctagt catgaaaaga actcctttct tttggttggt
     2701 ttagtcactt taaccatagc agaaaggggt tcttttttca tcacttaacg ggtgaagatg
     2761 aaaaagtaat tgtaagctgc cgtgaggcag tttcacatgg ttttaattaa aagtatgaat
     2821 tattcaggct atcattaatt ttataaaaaa aattaaatgt ttttagcact gccatataac
     2881 attcaaaaca ttcttctata gttggtttac ttccttgagg agaatgaacc aatttattac
     2941 gtttttctat gaaattttta atttcctttc ttatttcttt cggaaactca atattaaagt
     3001 accctttaaa catgctccct aataatttgt ctacaggggg agattgtaaa ttctcaaata
     3061 ttagagttaa atcaggtttc tcttgttgat aaaattcctt tacccctatt tcacaggctg
     3121 taattatcga aataaaccta tctctagtat ttgatatatt tttacttctt ttaaggagta
     3181 taagagaaaa ggggatactt tcgtgtccat gcatgtaatt aactaattgt tgagcttcag
     3241 aagttatatc tctaattata tagttaacgg aattaggaag tgtctttaac tctaatgaaa
     3301 tttctatcca attactatct tctaatctgt atatgctcga agtataattt gattcgtcag
     3361 caagcatcgc tacatcccaa acactgatca taaaatcttt taaacgttca atcatttcag
     3421 caatattgct aaaatcagct aatttttctt tagaataaaa aaaaacattt atatcagaat
     3481 caataaattc tattttttta ttactatatc gtcatcatta tcttgaccat ttatgtttat
     3541 tgttccctga gtggggagta cttctttcaa attcaagtta aatttatatt ccattacttc
     3601 tcctccaata tataaaaatt acttaactgt atccaaattt aatatgtaaa taaatcatta
     3661 atttttagct aaattctatg agaagtttat ttttgttgtt tttgctaatt aactaaaact
     3721 agtacaaaaa atttaaaata gattattaaa cctattgctt attctattca gtcatatata
     3781 taagcgtcat cctttagtaa ctaacatccc acactacaat agtattataa catatctatt
     3841 caacttcaaa ttgttgaaat ttaagccatt tatatttact tttcctcaac tttagaaatg
     3901 attttactaa ccttatatcc gtaatacgcg taacaaacac attcattaat aacaatcaac
     3961 actaagctat attagctttt taaatgacta gggtaaataa aataaggatc aaaaactttt
     4021 aagtttctga ccctttcctt acttccgatt ggttaatagt gatcttttgc agaataaata
     4081 aatatcgttt cattttcaac tctatatatc agtctatgtt catctgtaat tcttctggac
     4141 cattttccag ataaatcatg ctttaatggc tcaggttttc ctaatccagc aaagggggaa
     4201 cgatcgatat cttttattaa cttgttaatc ttttttatat tgcttttgtt tccttgctca
     4261 tgccaataaa gataatcatc ccaagcatca tcagaccaag ccttaatcat cagattcaac
     4321 ctcgattaag tcatgtgttt taaatgcacc tttggagaat tgttcatctc ctcgacgaat
     4381 tttttccatg acgtaattat tagaaagtgt tctcaacgtt tcttgcatag aatcataatc
     4441 tctttttgat aatacaacaa ctgtatcttc tacatcttta cttgttacaa taagtgtttc
     4501 agcatcctca ttaacttgtt tcatataact acgtaaattt tggcggaaat ttgaataagc
     4561 tactgcttcc attcctttca ccccttattt atttctataa aacaattgta cattatattg
     4621 tacaattaag caaatgatta atattctaac ttcttataat taaaagtgct atcactttta
     4681 gtttttagga taaaaagtga cgtcactttt tgagtgctgg tacctcaaat cctgcttttt
     4741 cttgggcaat caataaatct aacgcaatac acataatcct ggattcactt ttgccgtact
     4801 tctgctttag ttgctgcaat tctttttgtc tcttttcatc caacgtaacg ggtaaccgtt
     4861 tatttcctat tgcaattggc attagtactc tctcctttca tcgaaataac cctatgaaaa
     4921 atatggctgc aatcatcttg aatagtagac tcacaagggc taatacaaag cgccaaaaga
     4981 tcaaacaaaa taccagtatt gccaaaaata ctacgaagtt taaatgcaca gctgcagcat
     5041 ggcgcataag tatttcgcca acaaatagga ctaacaatag aggaatgatt ttattcatat
     5101 ggatctcctt ctttctctta ggttatcggg tgttgcccgc ttatttcgca ccacctaagc
     5161 ggcgggggcg gttggagcga ttggtgcgaa ataagaacca ttcccttagt tactaggttt
     5221 tttgtcctta tttcacacat tctcactttt cggtataaat gattattgcc tttttttcct
     5281 ttcaaatcgt tgatatggca ttcgtttacg gtcaagttca ttttggattt cttctgtatc
     5341 gtcgtaagta taggtgtcta aaaaatcagt taaagtcgtg taccagtcgt cgcctgggtt
     5401 atctacttct tctacatatt ccctcaaaaa tgcttcgggt acagcgagtt cataatccat
     5461 tcccattaac acgatagatt ccgttccaca cgtcaaaaat ctagtaaata caaggtaata
     5521 atcgtctatc gtcgcatctt tgctgtttag ctcttccatt tcttcttcca ttaattccat
     5581 gctctcaaaa attgaataat attctgattc tgagtaatag tgtttcctgc aaatcgtgta
     5641 gctgacaaag ttttcgacca gctcactcct ttctaggtaa acattcatga tgtatttttc
     5701 tgtttctagt cgtagaagct ccgttccttt ttttaccgtt tcaggacgac gtttatacac
     5761 gtctaaacga ttatggctga ctgtgacctt cgtttgactc gtttcacttt ccaaatacaa
     5821 ttgttcttcg ggttctgttg caaagtttta aatctactat caaataaggt agaataatag
     5881 aaaaagatag caggaggaat gacgatgaat c
//
LOCUS       DADVXE010000115         5779 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.118, whole genome shotgun sequence.
ACCESSION   DADVXE010000115 DADVXE010000000
VERSION     DADVXE010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.118"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..813
                     /locus_tag="KB913_002735"
     CDS             <1..813
                     /locus_tag="KB913_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBB6821023.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSLTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKIARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="KB913_002736"
     CDS             807..1229
                     /locus_tag="KB913_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821024.1"
                     /translation="MVNKLIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2363..3331
                     /locus_tag="KB913_002737"
     CDS             2363..3331
                     /locus_tag="KB913_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBB6821025.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIISRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     NFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIQKRYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKEPTSLQEKIKEQKRKLELL
                     QQLAELERKQNTPSKKINKQIADNNSDITPEFKENLLDNLQNLFKE"
     gene            3341..3829
                     /locus_tag="KB913_002738"
     CDS             3341..3829
                     /locus_tag="KB913_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBB6821026.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNITYLKKE
                     AVTTITKVLSGNESGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQIALETQ
                     QKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQNKEKKWWQF
                     WQ"
     gene            4125..4406
                     /locus_tag="KB913_002739"
     CDS             4125..4406
                     /locus_tag="KB913_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821027.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
     gene            4408..4824
                     /locus_tag="KB913_002740"
     CDS             4408..4824
                     /locus_tag="KB913_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821028.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
     gene            5438..>5779
                     /locus_tag="KB913_002741"
     CDS             5438..>5779
                     /locus_tag="KB913_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBB6821029.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2154 a          980 c          948 g         1697 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcccttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tttctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgcgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaaatagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaact cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctcgaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaagc
     1441 cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca aacgatacgt
     1501 ccataggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat ttggctagca
     1561 atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt cgagtgagcg
     1621 aatccaaatt tgcaactctg aagctttgca aatgagtgtg ccggcttccg taaaagtcta
     1681 ggtaacatta gtcgatatat acatagggct ctaatttgcg ttttaaggcg ttttaaacgt
     1741 tctggtatgt aattatacca aagcgacttt aaaacgcctt aaaacgaatt ttagaggttc
     1801 tgtagaacgt tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg ctttaaaaac
     1861 aagataaggg attttatcta gacttgtctt aaaacgccgt agatgagcgc tcagagcttc
     1921 taaaaggact ccttacgaac tgtttttaag caaaggagcc tttaggcgac tgcgcagttt
     1981 aatgtgagag cgtagcgatc acacctttaa agcgaccgta gggagcagat tcccagttta
     2041 ggaaatttcg cgaacctgtt tggagaaaaa aagtaggaaa attttaggcg ggaaattttg
     2101 cccccctctt ttataatctc ttttataacc tctttttaaa cctctttacc gtcggctgta
     2161 tccttactct cccaaggtgt gcagaatctt ttaggggtct ttttgtctgt ttttaggggt
     2221 ctttttgtct gtttttaggg gtctttttgt ctgtttttag gggtcttttt gtctgttttt
     2281 aggggtcttt aattaggggg ttgaccccca ttagaaagct ctttataatt ttgttaagta
     2341 gttaatcttg aaggaggatt ttatggcaaa tgaaattgtg aaataccacc atgaattaaa
     2401 tacgattcct ttacgcaaat ttacgtcagt agaaatgaat ttattcttct ctataatatc
     2461 tagaatgcgt gatgtaggcg ataaaaaagt acaatttaca ttcgaacaat taaaagattt
     2521 aagcaattat aaagcaactg caaatgttcg attcatagat gatttagaaa caacgtatga
     2581 caaattaatg gatttacgtt ttggtagaag aagtgctgac ggtttgcaac gtgaacgatt
     2641 tgttttattt aatcaattta aaatcgatgg aaaagctgat attccttttg ctgaaataca
     2701 agtccatgag aaagccttac ccttacttaa taatcttgaa gaatgggttc gatattctct
     2761 ccaacaattc aatgaattag aaagcagtta ttccaaaacc atgtttagat tattaaaaca
     2821 atacagaacc aaaggaattg ccaatttttc aaaagaagac tttcatgaat tacttgatat
     2881 ccctaaaagt tatagagaaa gtgatataaa taaaaaaatt ataaagccta ttcgccaaga
     2941 actaaccgca atcttcaaag gtttgacaat ccaaaagaga tacggaaaag gacggggaaa
     3001 gcctgtcatt ggctatcaat ttacatttaa acctgagata aaaaaatcag acgactttaa
     3061 caaacatgct ccaaccaaag aagaacaaaa taaagctttg gaactagcta atcaacaggt
     3121 tcaatctgaa aaagaaccta cttcattaca agaaaaaatc aaagaacaaa aacgaaaatt
     3181 agaactttta caacagttag cagaattaga aagaaaacaa aataccccaa gtaagaaaat
     3241 taacaaacaa atagcagata acaattccga tattacccca gaatttaaag aaaacttact
     3301 agataatctc caaaacttat ttaaagaata aggggttttt atgacagata aaactatcaa
     3361 agaattagca gatattctag gtgtttcaaa agataaagtg aagtatcaac tgaggaaatt
     3421 acctagtaat tttacctaca aaaaaggaaa tattacctac ctgaaaaaag aagcagtaac
     3481 aacaattaca aaggttttat caggtaatga atcgggtaac ttacctagtg aattacccga
     3541 ttcattacct accgattacc tactcaagga gattgaaact aagaataatc atattgaaga
     3601 aaaagatagg caaattgaaa aacttcaaat agctttagaa acgcagcaaa aattactcga
     3661 ccagcaacaa caactcaccc tacaagccaa tcaacaaatc aaaaaacttc acgaacaact
     3721 ccagctaacc tatgcagaag aatcttcaga aaaagaaccc ctttctgtta ctgaagaaac
     3781 tcaaaaagga caaaacaagg agaaaaaatg gtggcaattc tggcaataac ccaacaattt
     3841 ttattcataa aaattgttgg gttactttct ttttttgctt ttacaagcat agcgacatga
     3901 tctcacgtcg ctatttttta aagagcataa ggaaacgcgg tatcactttc ttacgaaagg
     3961 tgctaggtag gctgtgccta ccacgtttct aagaaaaaaa tttgctatca ctttttcgtc
     4021 attgtggata gcttatgtat agtgtttcgg caaaaaacag ctatacaaat actatatttg
     4081 tatgatatac ataaattata cacaaatgcg aaaggaattc ttctatggac attttagttc
     4141 ggaatattga tccaaaagtt atttcagaaa tagatagacg ttgccaagaa ctcacaacaa
     4201 aaactggcaa aaaatggagc cgtaatgcgt acctaaaagt tctaatcgaa aacgattttg
     4261 accaggcact taggcattac aaaaaagatc aattcgattt attactcgaa aaatttatcg
     4321 atatacaagc aaaaaatact gaaacattga acgactatgt tcatacaaac aaccaactca
     4381 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgttacc
     4441 ctttatccca gtcacattga cgttttagat tccatcatcg aaaaaaatcc agatatcaat
     4501 aactactcgg aagccattcg ttttctatgt atgagttatg aacctaatac taatacgaca
     4561 actaccagca accaagcaaa actaaatgcg atgggaaaag aaatttctat tatgtccgaa
     4621 atcattgcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4681 tctaaagtat atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ctcccgacga
     4741 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacat tcacttctag aaattttgac
     4801 ccaacaaact ttctaaaaag atgaaaaaga aaccgaaaat tttttctatt tctcagtttc
     4861 ttttttaggg ggcagtcttc cagcaagatt tgcaagttac cggtaacttg cacaaaaaaa
     4921 gaaaaatccg cttgtgcgaa tccttctttt tgcattttgg ggcgctgccc caatctccaa
     4981 atatcggtta tttaatagcg tggtaactca aaaaaataga acgtactctg aaataaaaaa
     5041 agactgctct aacgagcagc caataaaaaa taatgagcgt ttattcttga aaaagcagcg
     5101 cgcttatgaa gcgctgccaa aaatttacca tattttatga aaaataacaa gtttctaaaa
     5161 aggaatcggt taagattcac aaagaatcgt aaacagacaa tagcggaaaa tcaagcttcc
     5221 gaacgtacct tttagctaga ccaatgaaaa atcacaaagt gagcggctgg atcggttggt
     5281 agaggggcta cttggcatag tgtacattat gttaactaac gctataaata acgattatgt
     5341 tcccaaaaca atattttatg aactataaca aaaatttgtt atcgcatatt gtatatttta
     5401 attataggtg tataccactt aaatttaaca caaaggcgtg attattttga aacccaaaaa
     5461 gaaaatttat ctaggtctcc tcttttcctt gatgattgga atttttagta taggaattac
     5521 aaatacctat gcttcagaaa attctaattt caatatcaac tcccaaccaa ttgaagaaca
     5581 agcaattaat tttgcgaaaa ctgattttga acactccata acttcaattc ttttaatgga
     5641 aaataacacc gaaactgata ttaactatac tcttggttcg ccatttaaaa tgctcgatgg
     5701 agaaaatacg gcaaatagtt ctattttctt tccagtattt tcagacgctg ataatacgat
     5761 taaatatatt tataccgtc
//
LOCUS       DADVXE010000116         5607 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.119, whole genome shotgun sequence.
ACCESSION   DADVXE010000116 DADVXE010000000
VERSION     DADVXE010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.119"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(261..764)
                     /locus_tag="KB913_002742"
     CDS             complement(261..764)
                     /locus_tag="KB913_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBB6821030.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1123..2148
                     /locus_tag="KB913_002743"
     CDS             1123..2148
                     /locus_tag="KB913_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6821031.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2471..3349
                     /locus_tag="KB913_002744"
                     /pseudo
     CDS             2471..3349
                     /locus_tag="KB913_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
     gene            3825..3941
                     /locus_tag="KB913_002745"
     CDS             3825..3941
                     /locus_tag="KB913_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBB6821032.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            4869..5207
                     /locus_tag="KB913_002746"
     CDS             4869..5207
                     /locus_tag="KB913_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821033.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            5301..5531
                     /locus_tag="KB913_002747"
     CDS             5301..5531
                     /locus_tag="KB913_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821034.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
BASE COUNT         1888 a          845 c         1037 g         1837 t
ORIGIN      
        1 aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg ttaagatttt
       61 aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag cctgtcagtt
      121 tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa atagattttt
      181 ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt gtctattacg
      241 gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa taaaaaagct
      301 acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc taacttattt
      361 gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc tcctgttgta
      421 ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg aatcaattct
      481 gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag tctcttgaaa
      541 ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt ggtctcacgt
      601 aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac attgctgtaa
      661 gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa ccataataga
      721 aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat ctcctccatt
      781 taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag tttaaggacc
      841 aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg tttctttaac
      901 aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca aaacgactcg
      961 gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac taagtttatg
     1021 aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg gcatttcatc
     1081 ttggttcagc tttttttcca attactagga aggagggata gattgttcaa gacttatttt
     1141 cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct acttatcttt
     1201 attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt ttcatcatta
     1261 gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct gaaacgtatg
     1321 tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc gacttatgtt
     1381 ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt cgtgttgcga
     1441 ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc catgggaacg
     1501 agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt tatgggtgtc
     1561 gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc tgagcagaca
     1621 attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat cattgattct
     1681 gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt gaatctgcat
     1741 aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa cttggatgcg
     1801 atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg tgtgtcggca
     1861 ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac ttttctatat
     1921 ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt tcttaatccg
     1981 atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt gatcgaatat
     2041 cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg ggtaatgacg
     2101 gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa ggacaaatat
     2161 atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa ggtgttcaaa
     2221 agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa ctttcaaaaa
     2281 aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat aaactttcct
     2341 gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata gaaagtttaa
     2401 gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg gataatcagt
     2461 catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga aaataagcaa
     2521 tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag agcaaatgat
     2581 tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg aactaatgga
     2641 tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag aggaaccttt
     2701 tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa tttatcaacc
     2761 attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta gatttattca
     2821 tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga tttggcatta
     2881 cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat attttccgaa
     2941 agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata ttccttccga
     3001 tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc gtttttttga
     3061 actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt tactatcacc
     3121 caatcttact aaatagttga aaaaagagtc aaaaatctgt ctttttgcag ccgattatcg
     3181 attattatca gttgatgaac aggacgatag tggagtccct tggatctttg gacgagtaga
     3241 tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa aagagcaatt
     3301 gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag tttagtactt
     3361 cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc acgctctaaa
     3421 cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa
     3481 tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc ttctgtccca
     3541 gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac tagctataac
     3601 aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa cgtaataatg
     3661 aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt ttaacaagtt
     3721 gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt tcgatttgtg
     3781 ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa aaaacagata
     3841 tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa cgtgcgctga
     3901 agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga aacttaatta
     3961 aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg tgtaaggttt
     4021 ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta gaatctttct
     4081 tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa ccacaaagca
     4141 cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa cctcttattt
     4201 tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg aaacattttt
     4261 agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt catgaaatat
     4321 ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata agcagttacg
     4381 aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa aaaaatcagt
     4441 gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg ccgaaaaaat
     4501 atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa taataagttt
     4561 tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag taataaagta
     4621 tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa ttaatggtta
     4681 aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg tgatactaga
     4741 ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa tgaaaaagaa
     4801 gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt agccaagtaa
     4861 cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt cgtgctacag
     4921 aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct agtgagccaa
     4981 ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt atggtggtaa
     5041 ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt gaaaaggtga
     5101 gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc attttaacgg
     5161 attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca ctagtgaaat
     5221 actttatgat atagaaattg atgaaaattt actagatgta gcacaagaaa tcgatcatca
     5281 aaagcaggaa gctattcgat atgctggtag aaaagggaaa agaaaatatt tattacgtga
     5341 atgtagcaaa agttagagaa gatgaaaatg agtggaaaga attcaagagt cgctactcaa
     5401 ttaactcgac tccgacattt acagtttaca gagaaggatc gatagaaaaa actgtttttt
     5461 ggactaaaga aagtggaatg tctttagctg aagtagaaga gtttttggat tatgttagta
     5521 tgcaacagta agggagttct tattatgaaa aattttgaca catattatgt tattgttttt
     5581 tcgatatctt tgctgttaat attacta
//
LOCUS       DADVXE010000117         5571 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.120, whole genome shotgun sequence.
ACCESSION   DADVXE010000117 DADVXE010000000
VERSION     DADVXE010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.120"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(1014..1304)
                     /locus_tag="KB913_002748"
     CDS             complement(1014..1304)
                     /locus_tag="KB913_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821035.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1706..1942
                     /locus_tag="KB913_002749"
     CDS             1706..1942
                     /locus_tag="KB913_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821036.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="KB913_002750"
     CDS             1949..3901
                     /locus_tag="KB913_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBB6821037.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="KB913_002751"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="KB913_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBB6821038.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4797..5489)
                     /locus_tag="KB913_002752"
     CDS             complement(4797..5489)
                     /locus_tag="KB913_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6821039.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSWKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1812 a          972 c          902 g         1885 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata
     4561 agcaattttt tctataagtt atattatcat aataccacaa aatcacaaat tttcattcaa
     4621 ttatcatttt caattgcatt ttataaatca ttttgtatgt aatttggtat gtaagttaaa
     4681 atgaaaaaag tagtccattt tgaagtacat tttgtcattt tgtactccaa aactgaacta
     4741 cttagtatag attactgttg cttctttact aatttaggtt tacttgttaa gaaagattat
     4801 ttacgcaaat gttcttcaac aatttgctga gatttatcag ctgtatcttc cacttcatct
     4861 tttgcttttt ctaacttttg aatatattgt ttccagcttg agttttcagc agttgcttcg
     4921 tctaatttct tttgtgtatc tgttaactga gtttctacat ttgttttttc ttgtgtcagt
     4981 gttgcgattt gttgattcaa accatttaca gtattttgta attctgaaag ttttgcttgt
     5041 gcttcttgta gtcttgctgt ccaatctgca ttcagatgat tgatttcatc atttttttgg
     5101 ttgatctcat ctagtttgac attgatttca ttttgtttgc tttgtagttg tgcatccttg
     5161 ctgactaatt gactttctaa gttttgtttt tctgctgccg attgattttt ttggttttct
     5221 aattcattta cttttgtttg gtattcttgg acatctgcct ttgaatcttg caatgtctgt
     5281 tctttttgtg ctagtcgagc ggtaagatct gtaatcgctt gctctttatc tgtcaatgta
     5341 tgatcaagct gtgtcagatt ctcattgatt gtatcaatat ctgtctctcc accccacaaa
     5401 ataatttcat ttgcgtaccg cgtgcctgtg tagccaatta gacatagaaa tgcaacgaca
     5461 atcccaccag taataaattt ctttttcatt tgcatagctc cttaatccaa tacttttaca
     5521 tgctaaaagt aagtgatctc aaacacaatg tcaagcgttt ttaaattaca t
//
LOCUS       DADVXE010000118         5514 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.121, whole genome shotgun sequence.
ACCESSION   DADVXE010000118 DADVXE010000000
VERSION     DADVXE010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.121"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..1350
                     /locus_tag="KB913_002753"
     CDS             <1..1350
                     /locus_tag="KB913_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6821040.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2827
                     /locus_tag="KB913_002754"
     CDS             1484..2827
                     /locus_tag="KB913_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6821041.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2939..4390
                     /locus_tag="KB913_002755"
     CDS             2939..4390
                     /locus_tag="KB913_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBB6821042.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            4739..5371
                     /locus_tag="KB913_002756"
     CDS             4739..5371
                     /locus_tag="KB913_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBB6821043.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
BASE COUNT         2123 a          773 c         1066 g         1552 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttaaaggca gtaacaggat taaacattga
     2821 aacataatcg ttactaaatg aaatcaagaa atatactgta ttactcaatt cattgaaaat
     2881 atttatcata atttttaata gaaaacacta ttaaagagaa aaaagagagg taaatcaaat
     2941 gaaaaaatct ttaaaacttg catcagcagt tatattaatg tcccaactcc ttatagcaac
     3001 acctttccat gtgttggcaa gcgaaaattc aacatacaaa attgcaaaag aaagaaccga
     3061 gacgactgaa atgagtaatt ccgatgtaac agcagagagt agtgaacttt tgacaacttc
     3121 atcaagtgaa agtagtacga cttcaaatgc cgagtcttca acaacttcat caagtgaaag
     3181 tagtacgact tcaaatgccg agtcttcaac aacttcatca agtgaaagta gtacgacttc
     3241 aaatgccgag tcttcaacaa cttcgtcaag tgaaagtagt acgatttcaa gtaccgaatc
     3301 ttcaacaact tcaagtagta caagtgaaat aacttcttcg aaagtgacaa aaccaaacca
     3361 tatagaatct tcaaaaaagg aagcgccaaa aacggaagga caaacaaaaa ctttttcgac
     3421 accacagcaa atagaatcaa cagaatcttt ccaatcacaa ccaatactat ctggtaatga
     3481 agaaattcat tttgacaaaa atgaatctgt agaaaatttt attatgaaaa ttggtgagtc
     3541 tgcgagaaaa attggtcaga aatatgattt atatgcttct gttatgattg cacaagcgat
     3601 cttagaatct gccagtggtc aaagccagtt agctcaggca ccgaattaca atttatttgg
     3661 gataaaagga acttataatg gaaactttgt cattatggta acaaacgaag atttgggtaa
     3721 tggaacgctt tatacgaccc aatcaaaatt tagagtgtat gaaaactatg aggaaagctt
     3781 tgaagattat gccaaattat taactaaggg aattagtgga aataaagatt tttatgcagg
     3841 agcattaaaa gctaatagta aaacatatcg agaagcaact aaattcctta caggacggta
     3901 tgcaacagat acacaatact atttgaagct aaatgaatta attaaaacct acgatttaac
     3961 caactatgat aaagaagtta aaggtccaca aatgagtaag actggatacc aagtgcctat
     4021 tcataattat tcaataacca gtttgtttgg aaatcgtgga aatgaatttc accgaggact
     4081 tgatatggca gctacacagg gtgagccgat tcatgcagtt aaagctggta aggttgttaa
     4141 agcagagttt cactactctt ggggaaatta cgtggtgata caacacgaag atggatcaac
     4201 cgcgttatat gctcaccagc aacaatacct agtaaaaact ggagataatg ttttgcaagg
     4261 acaaataatt ggctatgtag gaagtactgg gaatagtact ggcccacacc ttcatttgga
     4321 aatttgcaaa gatagtagtc tttctcagag catgttagtt gatccgaaaa ccttattatt
     4381 cggagactaa aaaaggtaat caatctgaca aagtaacaag aaaatggttg gattcttaga
     4441 cctttgatca ggatattgag actggaattg atatctcgat tacgatgggt ttgacaaata
     4501 aaacaagtcc attatcgaat atcgagtgta ttattgccgt ctttatgctc atattttgag
     4561 caggtttcac tagatgaaaa caatttatct atcttgagga tttcgtgtac gtatcgttca
     4621 gtcttgtatt gtaaattagt cataaaatca gactaagaaa aattggaaat atttttttct
     4681 gatttattaa aagttaattg aaattatatg gtacttcttt cttgggaggg taggtgcagt
     4741 gaaggaaaga tatggtcacc ttactgttgt tgaggagatt actcataatg gatataaaaa
     4801 atatcgttgc ctatgtgact gtgggaatga aacgattgta tatcgatcaa acttactatc
     4861 aggtagaacc aaaagttgtg gatgtggaaa ttataaaaat aggcataaat ataaaaattt
     4921 gacaaataaa acttttggta agttagttgc aatcaagcca actaaactgc gaagtgaagg
     4981 aactgttgtt tgggaatgtc aatgtctgtg tgggagaaaa aagttagtat cggcaaagcg
     5041 acttctaaaa ggtgatgtaa aaagctgtgg atgtttgaaa tcaaaaaagc atcacattga
     5101 aaataaaaaa ttcggattac ttactgcaaa gtatcctttg gacaataact gttcatggaa
     5161 aacaaaatgg gtttgtcatt gtgagtgtgg cagtatgtgt gagataagtt atagtaactt
     5221 attttttgga catactcaaa gttgtggatg tttaaaaagg caagaaacaa ggacatgtgt
     5281 tgaagggaca gtaatagagt gtctaacgtc aaaattaccg aaaaataata caagtggtgt
     5341 taagggagtt tatcgttcta aagagaaata gattgcgtat ataactttaa aaaaaaagag
     5401 gtactattta ggatcgtatg attctattaa gagtgcagct caagctagaa aagatgctga
     5461 aaataaattg tttcaacctt tgattgacaa atatcgaggt aatcattaat tatt
//
LOCUS       DADVXE010000119         5311 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.123, whole genome shotgun sequence.
ACCESSION   DADVXE010000119 DADVXE010000000
VERSION     DADVXE010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.123"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="KB913_002757"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="KB913_002757"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBB6821044.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="KB913_002758"
     CDS             complement(1297..2133)
                     /locus_tag="KB913_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6821045.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="KB913_002759"
     CDS             complement(2317..3534)
                     /locus_tag="KB913_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6821046.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3862)
                     /locus_tag="KB913_002760"
     CDS             complement(3683..3862)
                     /locus_tag="KB913_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821047.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3917..4000
                     /locus_tag="KB913_002761"
     tRNA            3917..4000
                     /locus_tag="KB913_002761"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..4818)
                     /locus_tag="KB913_002762"
     CDS             complement(4240..4818)
                     /locus_tag="KB913_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821048.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(4824..5207)
                     /locus_tag="KB913_002763"
                     /pseudo
     CDS             complement(4824..5207)
                     /locus_tag="KB913_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347134.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1082 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca t
//
LOCUS       DADVXE010000120         5246 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.124, whole genome shotgun sequence.
ACCESSION   DADVXE010000120 DADVXE010000000
VERSION     DADVXE010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.124"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            32..388
                     /locus_tag="KB913_002764"
     CDS             32..388
                     /locus_tag="KB913_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich SFCGS family protein"
                     /protein_id="HBB6821049.1"
                     /translation="MIKVVIADRMGKGQNVAKGVEAAGGKAVVVPGMGADMRLGDVMQ
                     QEHADMGISFCGSGGAGALTAATKYGYPERHGMRSIEEGITAIKDGKTVLGFGFMDQE
                     ELGKRLTEEFIKKHGK"
     gene            404..754
                     /locus_tag="KB913_002765"
     CDS             404..754
                     /locus_tag="KB913_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HBB6821050.1"
                     /translation="MSVQKTIQQKVIVSGKGETKQHAFASALAEIQNKIMEQSNVLLR
                     IEPVNVDILKAVENKYTERFLFFFFPRQRISYEVELSVTVAVTEIKLADISFSQQMTE
                     DPNGIAIPFVTKKI"
     gene            783..1562
                     /locus_tag="KB913_002766"
     CDS             783..1562
                     /locus_tag="KB913_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HBB6821051.1"
                     /translation="MDFVIILVKSVIIGGLLGFAASVGAARMFHAPNTQGLGAFRTLG
                     EMNACMGDPASHFSFGLGFFFNAWASSVGAGAFTQDVTHRIIPNWAAAALLAKNKDVT
                     QTMHDPKKMGIIGAVIGAVVVAFLNTTAAAIPEALQVTAVSVLVPAATILINTVMPVI
                     FWLAALDAGKRTGFWGTLFGGIAQLIMGNAVPGVVLGILIGKGVDESGWNRVTKSMMI
                     AIVLLFIFSGFFRGFDMEMIKSFQLQVPNWLDNLHNIFSVK"
     gene            1573..2235
                     /locus_tag="KB913_002767"
     CDS             1573..2235
                     /locus_tag="KB913_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HBB6821052.1"
                     /translation="METTEEQAKVLEAKRQKSFWFADWSFPLIVGIMSAAVFAGTHMY
                     VMYGVGAFNEVSIVAMLKAGLDGGSYGAAAAFGASFLFARILEGSLVGILDLGGSILT
                     GIGIGVPAILLSMKIAAPIDNFALSLLTGLVLGLIVGGIIVLIRKFTINQSNSTFGAD
                     VMMGAGNSSGRFLGPLIILSACAASIPIGIGATLGALGFYAWKKPIAGGAILGAIFPA
                     VN"
     gene            2254..3360
                     /locus_tag="KB913_002768"
     CDS             2254..3360
                     /locus_tag="KB913_002768"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBB6821053.1"
                     /translation="MFDTLIKNGRLVDGSKIEVAIEKGMIKAVAAEINQPAQEVVDLE
                     GKYYLSAGWIDDHVHCYEKMNLYYDYPDQIGVEKGVTTVIDAGTTGAENIREFYQLTK
                     SVKTNVYALMNISKWGIVKQDELADLTKIQEDLVSTALAELPEFIVGIKARMSKTVVG
                     ENGIKPLELAKKIQTENNDLPLMVHIGSAPPELEEVLSRMERGDVLTHCFNGKPNGIL
                     DPKTDQIKNFVWDAYNNGVVFDIGHGTDSFNFHVAETALKAGMKATSISTDIYIRNRT
                     NGPVFDLATTLEKLRVVGYSWEEIIEKVTAVPARNFHLKNKGQLAVNYDADLTIFEIV
                     ENEKELKDSNGFTRIAKEQILPIKTIIGGVIYDN"
     gene            3350..4441
                     /locus_tag="KB913_002769"
     CDS             3350..4441
                     /locus_tag="KB913_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBB6821054.1"
                     /translation="MTISYGKFDLKEVINASGKMTILGVSKVSESVLAAQRFGGEHFF
                     EMSDLAIKTGAYLSQLLKVEDAQIVSSASAGIAQSVAALIGQGDMYHVYHPYTEKIAR
                     REIIIPKGHNVDYGTPVEVMVAQGGGKVIEAGYANMCTPEHVSMMITEKTAALLYIKS
                     HHAVQKSMLTVAEMVEVAKAHRLPLIVDAAAEEDLFKYSEMGVDLVIYSGAKAIEGPS
                     AGLVIGKKKYIQWIRLQSKGIGRAMKIGKDNILGFTQALEDYLKNGSESGDSMKQRLA
                     PFVNAINQLPDLSAKIVQDGAGRDIYRASVTINGDKSAKEVIQELKARNPAVYTREYQ
                     ANNGIIEFDIRSVSQNEMEKIIKRLREIM"
     gene            4454..5194
                     /locus_tag="KB913_002770"
     CDS             4454..5194
                     /locus_tag="KB913_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBB6821055.1"
                     /translation="MSVIPNYYKNRVCLNVLAHSVENAKACYEAAEGHVVLGVLSKNY
                     ASDEAAIEDMKRYQDATNNALSVGLGAGDPNQSQMVSRLSGVLQPQHVNQVFTGVGTS
                     RALLGQNDTVINGLVSPTGKIGYVNIATGPLSSQAPAAEVPIETAIQMLQDMGGTSIK
                     YFPMKGLAHREEFKAVAEACAKYEFYLEPTGGIDLSNFEEILKIAIDAGVKKVIPHVY
                     SSIIDKETGDTRIGDVKILLSMVKKIIH"
BASE COUNT         1682 a          864 c         1253 g         1447 t
ORIGIN      
        1 acaaatgata ttttacgagg aggaaacaat catgattaaa gtagttattg cagaccgtat
       61 gggtaaagga caaaatgtgg ccaaaggggt agaagcagct ggtggaaaag cagttgtcgt
      121 accaggaatg ggggcagata tgcgtttggg cgatgtgatg caacaagagc atgcagatat
      181 gggtatctct ttttgtggta gtggtggtgc aggtgcatta acagcagcaa caaaatatgg
      241 ctatccagaa cgacatggta tgcgttcgat tgaagaaggg atcacagcta tcaaggatgg
      301 caaaactgtt ctaggtttcg gctttatgga tcaagaggaa ttagggaaac gtctgacaga
      361 agaatttatc aaaaagcatg gaaaatagaa agagggacat gaaatgagcg ttcaaaagac
      421 aattcagcaa aaagttatcg tctccggtaa aggggaaaca aagcaacatg cttttgcatc
      481 agcgttagca gaaattcaaa acaaaataat ggaacaatca aacgtattat tgcgaatcga
      541 accagtcaat gtggatattt taaaggcggt cgaaaacaaa tacacagaac gctttctatt
      601 tttcttcttc ccacggcaac gtattagcta tgaagtcgaa ctctctgtta ctgtggctgt
      661 aacagaaata aaattggcag acatatcgtt cagccagcaa atgactgaag atccaaatgg
      721 gattgccatt ccatttgtaa ctaaaaaaat ctaattttga atcataaggg ggaaagaata
      781 acgtggattt cgtaatcatt ctagtcaaat cggtcattat cgggggatta cttggttttg
      841 cagcatctgt cggggcagct cgaatgtttc atgcacctaa tacacaaggt ttaggagctt
      901 ttagaacatt aggcgaaatg aatgcctgca tgggtgatcc agcttctcat ttttcatttg
      961 gtttaggctt tttctttaat gcatgggctt cttcagttgg tgctggtgca ttcacacaag
     1021 atgtgacgca tcgaatcatt cccaattggg cagcggcagc acttctagca aaaaacaaag
     1081 atgtcaccca gaccatgcat gatccgaaaa aaatggggat cattggagcg gttatcgggg
     1141 cagtggtggt agccttctta aacacaacag ctgcagcaat tccagaggcg ttacaagtga
     1201 cggcggtttc cgttttggta ccagcagcga cgattctgat caatacagta atgccagtta
     1261 ttttttggtt ggcagcttta gacgcaggga aacgaactgg tttttggggc actctttttg
     1321 gtggtatcgc gcaattgatt atgggaaatg cggtacctgg tgttgttcta ggaatcttga
     1381 ttggtaaagg cgtcgatgag agcggttgga atcgcgtcac gaagagcatg atgatcgcta
     1441 ttgttttatt atttattttc agtggatttt tccgtggatt tgatatggaa atgatcaaga
     1501 gcttccagct tcaagtgcct aattggcttg ataacttgca caacatcttt agtgtgaaat
     1561 aggaggagaa tcatggagac aacagaagaa caagcaaaag tattagaagc aaagcggcaa
     1621 aagagctttt ggtttgcaga ctggtctttt ccgctaatcg taggaattat gtccgctgct
     1681 gtatttgcag gaacacacat gtatgtgatg tatggtgtgg gtgcattcaa tgaagtttcg
     1741 atcgtggcga tgttaaaagc cgggctggat ggcggatcct atggcgcagc ggcagcgttt
     1801 ggtgctagtt tcttatttgc cagaatttta gaaggctctt tagttgggat cttggactta
     1861 ggcggttcga tcctaactgg gatcggaatt ggggtaccag caattctctt aagtatgaaa
     1921 atagcggcac caatcgataa ttttgcactc tctttattga ctggtttggt tctaggtttg
     1981 attgttggtg gcatcattgt cttgattcgt aaatttacga tcaatcaatc aaattccact
     2041 tttggtgctg acgtcatgat gggggcagga aattcatctg gacgtttttt gggtccatta
     2101 attatattaa gcgcgtgtgc agcatctatt ccaatcggca ttggcgctac attaggagca
     2161 ctaggattct atgcttggaa aaaaccaatt gctggaggtg ctattttagg agcaatcttc
     2221 ccggcagtaa attaatagaa agagggtcat taaatgtttg atactttgat taaaaatgga
     2281 aggttagttg atggatctaa aatagaggtc gctatagaaa aaggcatgat taaagcagtt
     2341 gcagcagaaa taaatcagcc ggcgcaagaa gtagttgact tggagggaaa gtattattta
     2401 tccgctgggt ggatcgatga tcatgtccac tgctatgaaa agatgaatct ttattatgac
     2461 tatcctgatc agataggggt cgaaaaaggt gtgacgacgg tcattgatgc tggaactacg
     2521 ggagcagaaa acatccgtga attttatcaa ttgacgaaat cggtcaagac aaatgtgtat
     2581 gcgctaatga atatctctaa atggggcatt gtcaaacaag atgaacttgc tgatctaaca
     2641 aagattcaag aagatctagt aagtactgcg ttagcagaac tgccggaatt tattgtcggg
     2701 attaaagcga gaatgagtaa gacagttgtt ggtgaaaatg gcattaagcc attagaatta
     2761 gctaaaaaaa tccagacaga aaacaatgat ctgccattga tggttcatat cggttctgca
     2821 cctcctgagt tagaagaagt attgtcaaga atggaaagag gcgatgtatt gacccattgt
     2881 tttaatggaa aaccaaacgg tattttagat ccaaagacag atcaaattaa aaactttgtc
     2941 tgggatgctt acaataatgg tgtcgtcttt gatattggac atgggacgga tagctttaat
     3001 ttccatgtgg cagaaaccgc actaaaagca ggaatgaaag ctacctctat tagtacggat
     3061 atctacatcc gcaatcgtac aaatggccca gtttttgatc tagcaactac tttagaaaaa
     3121 ttgagggtag tcggctattc ttgggaagaa atcattgaaa aagttacagc agttcctgca
     3181 cggaattttc atttgaagaa taagggccag ttagctgtca attatgatgc agatttgacg
     3241 atatttgaga ttgttgaaaa tgaaaaggaa ttgaaagatt ccaacggatt tacacgtata
     3301 gctaaagaac aaattttacc gattaaaaca attattggag gcgtcatata tgacaattag
     3361 ctatggaaag tttgatttaa aagaagtcat taatgcatcg ggaaaaatga cgatcctagg
     3421 ggtttctaag gtatctgaaa gtgtcctagc agcacaacga tttggaggcg agcatttttt
     3481 tgagatgagt gatcttgcca tcaaaaccgg cgcttatctt tctcaattac tgaaagtgga
     3541 agatgcgcaa atcgtttctt ctgcttcagc agggattgct caatctgttg ctgctttaat
     3601 cggacagggc gacatgtacc atgtctatca tccctataca gaaaaaatcg ctagacggga
     3661 aatcatcata cctaagggac ataatgtaga ttatgggaca ccggttgaag taatggttgc
     3721 tcaaggtgga ggaaaagtca tagaagctgg ctatgcaaat atgtgtacac cggaacatgt
     3781 ttccatgatg attacggaaa aaactgctgc gcttctatat attaaaagtc atcatgcagt
     3841 tcagaaaagt atgctgacgg tggcagaaat ggtagaagtt gccaaagctc atcgtttgcc
     3901 attgatcgtt gatgcagctg cggaagaaga tttattcaaa tatagcgaaa tgggcgttga
     3961 cttagtgatt tactctgggg caaaagcaat cgaaggtccg agtgccggac tggtcatagg
     4021 aaaaaagaag tatattcaat ggattcggct acagtctaaa ggtattggcc gagcaatgaa
     4081 aatcggtaaa gataatattt taggctttac ccaggcacta gaagattatt taaaaaatgg
     4141 gagcgaatcc ggtgactcca tgaagcaacg attagcgcct tttgttaacg caatcaatca
     4201 acttcctgac ctttcagcga aaatagttca agatggtgcc ggcagagata tttatcgagc
     4261 aagtgtaacg attaatggcg ataaaagtgc gaaagaagtc attcaggaat taaaagcacg
     4321 aaatccagca gtctacaccc gagaatatca agcaaataac ggaatcattg agttcgacat
     4381 tcgttccgtc agccaaaacg aaatggaaaa aattataaaa agattgagag aaatcatgta
     4441 ggaggctttt aaattgtcag ttatcccaaa ttattataaa aatcgtgtat gtttaaatgt
     4501 attagctcat tcagttgaaa atgcaaaagc atgctatgaa gcagcggaag ggcatgtcgt
     4561 actaggtgtg ctatcgaaaa attatgctag cgatgaagca gcaatcgaag atatgaaaag
     4621 gtaccaagac gcaaccaata atgcgttgtc agttggatta ggcgctggag atccaaacca
     4681 aagtcagatg gtttcgcgtt tatctggggt tttacaacca caacatgtca atcaagtatt
     4741 tactggcgtg gggacttctc gtgctttatt gggccaaaat gatacagtca tcaatggatt
     4801 ggtttcacca acaggtaaga tcggctatgt caatattgct acaggtccgt taagttcaca
     4861 agcgccagca gctgaagtgc ctattgaaac tgccattcaa atgctgcaag acatgggagg
     4921 tacttcaatc aagtatttcc cgatgaaagg cttagcacat agggaagaat ttaaagcagt
     4981 tgcggaagct tgcgcaaaat atgaattcta tttagagcca acaggaggaa ttgatctttc
     5041 aaactttgaa gaaattctga aaattgcaat cgatgcaggt gtaaaaaaag tgattcctca
     5101 tgtttatagt tcaattatag ataaagaaac aggagatacg cgtataggag acgtaaagat
     5161 actattaagc atggtaaaaa aaattattca ctaactcatt agaaaataag aagcttattc
     5221 cagaatgaaa ttaaatggaa taagct
//
LOCUS       DADVXE010000121         5025 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.125, whole genome shotgun sequence.
ACCESSION   DADVXE010000121 DADVXE010000000
VERSION     DADVXE010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5025
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.125"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            283..522
                     /locus_tag="KB913_002771"
     CDS             283..522
                     /locus_tag="KB913_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821056.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="KB913_002772"
     CDS             complement(884..1144)
                     /locus_tag="KB913_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821057.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="KB913_002773"
     CDS             complement(1329..1826)
                     /locus_tag="KB913_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBB6821058.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="KB913_002774"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="KB913_002774"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBB6821059.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="KB913_002775"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="KB913_002775"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBB6821060.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..5015)
                     /locus_tag="KB913_002776"
     CDS             complement(4548..5015)
                     /locus_tag="KB913_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821061.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
BASE COUNT         1529 a         1043 c          771 g         1682 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgcaa
//
LOCUS       DADVXE010000122         4933 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.126, whole genome shotgun sequence.
ACCESSION   DADVXE010000122 DADVXE010000000
VERSION     DADVXE010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.126"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            85..972
                     /locus_tag="KB913_002777"
     CDS             85..972
                     /locus_tag="KB913_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBB6821062.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="KB913_002778"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="KB913_002778"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBB6821063.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="KB913_002779"
     CDS             2274..2720
                     /locus_tag="KB913_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6821064.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="KB913_002780"
     CDS             2993..4345
                     /locus_tag="KB913_002780"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBB6821065.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="KB913_002781"
     CDS             4516..4803
                     /locus_tag="KB913_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821066.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1395 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt ttt
//
LOCUS       DADVXE010000123         4859 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.127, whole genome shotgun sequence.
ACCESSION   DADVXE010000123 DADVXE010000000
VERSION     DADVXE010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.127"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(170..1189)
                     /locus_tag="KB913_002782"
     CDS             complement(170..1189)
                     /locus_tag="KB913_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBB6821067.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RADVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1186..1410)
                     /locus_tag="KB913_002783"
     CDS             complement(1186..1410)
                     /locus_tag="KB913_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBB6821068.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            complement(1407..1700)
                     /locus_tag="KB913_002784"
     CDS             complement(1407..1700)
                     /locus_tag="KB913_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821069.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            complement(1737..1874)
                     /locus_tag="KB913_002785"
     CDS             complement(1737..1874)
                     /locus_tag="KB913_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBB6821070.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            complement(1876..2307)
                     /locus_tag="KB913_002786"
     CDS             complement(1876..2307)
                     /locus_tag="KB913_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821071.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            complement(2321..2815)
                     /locus_tag="KB913_002787"
     CDS             complement(2321..2815)
                     /locus_tag="KB913_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821072.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            complement(2815..3264)
                     /locus_tag="KB913_002788"
     CDS             complement(2815..3264)
                     /locus_tag="KB913_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821073.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            complement(3268..3888)
                     /locus_tag="KB913_002789"
     CDS             complement(3268..3888)
                     /locus_tag="KB913_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821074.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            complement(3888..4796)
                     /locus_tag="KB913_002790"
     CDS             complement(3888..4796)
                     /locus_tag="KB913_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBB6821075.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
BASE COUNT         1325 a         1050 c          763 g         1721 t
ORIGIN      
        1 ccataaacaa tcaaccagta gaatgtgtgg caacaaacct gttatcgcat agcttggagt
       61 gtgactatta tgggtgatag tgaagatatg cgataacatc actattttat cgaatgattt
      121 ttatagttgt caatatagtt atgtaatgct cctcaacgag gagctatttt tatcgtttag
      181 gaatatttaa ataccaacgt ttgtcatgga aatcttgcgc accgccttta gtgtttccct
      241 ctggatcatt cgttgcccgc atcatgacat agactttctt attagggaag ttacgcatgt
      301 taaaagatac atgatagcca acatttccag aagtattata agcttgattt acatctgctc
      361 tataaattcc atcagctctt actcgagcta attctttccc agtattgtaa tccataatga
      421 agatatactc gtatttatag ttagcaatgt gccatccagc tacatgcaaa tttgcatttt
      481 cgatttctcc aaactgatca atgtgggcgt aattcgttcc atctgtcagt gtaggattag
      541 ctgcaccagc tcgtgttgga tcaatgacag gcttgttttc agaagttgtt ggattttcat
      601 cggtaaatcc atgagctaaa tcatatgcta atttttcttt acttacgccc atttcagaaa
      661 gataaccgta aggatctgta tgatcgcccc agatgttttg tgttacccat aaatgcgatt
      721 tgattcccgg ttggttataa ggagtgtcca acgttaatgg aataccatat ttcattgctg
      781 aatctctagc caattcaacg tatgccttgt agtttttctc aaacgttgct ttatcatgtg
      841 tgtgttgtaa ctcaatctgc acaggactgt tggcattagc atacgaacca gcaccgtact
      901 gtacataacc aggttgaccg acttgataaa caattccgcc gtctcccaca atataagcag
      961 tataagcgct agtccatgaa cgttgcatat actgcgcttc attgcgtcct gttgctgttt
     1021 cattagccgt ttcatgcagt aaaatatact gattatttgc tacttgtgag ctaccttcat
     1081 ttgcgcccaa attaaattca ttgttgatag tataggcaaa tccgttaatt ggcaataaaa
     1141 aaagagccgt taacaggctc atcgcagtaa tagtaatttt ctttttcatt tgtttcctcc
     1201 ttcttcgctt tcagccgaga acattttgta ggttcgattt gatacaccca acacactccc
     1261 taaaaacgcg ccaaaaccag taatgatgac aacacagata tctgtgtact gccaattgag
     1321 cgctttacca actaacccca cgaaagtagc tagtgcggga ataattacca gtgcgaacca
     1381 ttttagtact tcgaacgttt tattattcat tttcttctct ccctaaacaa agttttgatt
     1441 tgttgcgtgt gttccaccaa tttttctgta tgtgtatcta atctttcatc gtgtttcttt
     1501 agttcttcat gaatcatcaa tcgatctgat ttgctcgatt ctaaatcttt agtcagcaaa
     1561 tctaaattgt ggcttacttt tgaaagagtc tcagtaattt tcgagaaaga tgcagcaatc
     1621 ggtctaatta ctaataaaat caaagaaacg atagcggtta ttgatcctgc tatcattccc
     1681 cattccccta aattaatcat gtgacaactc ctttacctta aataaaaacg catcaattaa
     1741 gatgcgctct tatctttatt aatgatttta tctgcttctt cgtctgtaat gcataatgga
     1801 acgaaaacca ttacttgttc gttagtgaaa cagccccagt catacattag tttgatatct
     1861 tcatatgaat acatgttact tcccaccttg taattgtttt ttgatttctt cgatttcctt
     1921 ggtattttgt acagaagcaa gcatcgtttt tgaattcaac tgcgctaaac tttctgactt
     1981 ttctttcaat aagacatttt cttgcttgat tgctacattg tttagcattg ctttagaatt
     2041 tagctgtttc aattcatcat tttctgcctt cagcgtttcg tataatgcct taatattagc
     2101 caattcatct acgctatcaa cagcattccc ttttttctct tcttcagtag ctaactcaac
     2161 ccactgtttt ttatcaaaat caaatcttgg tctccagtta ggaactggtg gtttaatctc
     2221 tgtacagttt tcagggatat tttcttgatt gttcaaaatg atttgctcga atccgtaagg
     2281 cttgattgat ttgtaaacta ctttcattag atttcctccc ttaaattgaa taagtgataa
     2341 caaatgaata agctgatcca taacttgaat ttcttctcca tttaatggct ccgtctgcgc
     2401 caatagatag ttgagcactg ttcaaagtag aacggtctat tgacccaacc agttgttcaa
     2461 aactaattgg tgtccgatag ccttctggaa cagttaaaat aaccgaatca ttcccgccac
     2521 tactttttcc gtttaaagcc acaaaatata tagaaactgt ttttccttca cgataaagct
     2581 ttgctgtccc tgtattaccg ttagtgacaa ccagatttac cacttcatat ctgttatcat
     2641 cagtcgtcaa aacacgttta ttattgattg ttacagaacc tgaaaaattc ttatgtcctg
     2701 caatggcttg gtctccatct gtctgcacca atgcttcttt accatcaata gcttctacat
     2761 gcgtttttaa gtatttagca actccgtctt cttttaattg aacaatatca gccattaaac
     2821 cgtccccact ttctcaaatg taatattcgc taatccatca agtttcactt tatcggttgc
     2881 tgacattaaa cctgctgtcg tagttgtagc attacctgga tttttctgtg ctccagctgc
     2941 aattccatcc aacttagttt tatctgtgga cgacatcaac ccatttgctg tagttgtagc
     3001 tacagctgta gttgtggcat ttattccagg atcaccttta tctccctttg gtaaaacaaa
     3061 attaaatcta gctgcagatg atgttcctac attcgtaaca gaagcggttg aaccactaga
     3121 aacggttcct atggtaattg ttgctgcttg gccaggatcg cctttatctc ccttcaccgt
     3181 tgttggtttg ccttctatag cattccaatg agtttgtgga taaacctgta cattgctttg
     3241 ttttattttt acgatatctg tcattctcta tacctcccca attttttcaa aagtaaaatt
     3301 tggaattctt tcgtttgtgt aattttctgc ttgatttaca gcttcttgga atttttgatc
     3361 tacatatgac tgattgacac caccagtccc actaccacct gtagaactaa ttgttccatc
     3421 ttcatcaata gtgatgtttt ctccagcagt ataatttttc agtgaatcga gtttttcttt
     3481 taactccagc gaaaaattga catcagattg tctgactgca gagactttcc ctgtctcatc
     3541 aatcgtcaat aattcaccaa cttttatgcc acccaaacgg tcgatagtgg caactggcaa
     3601 cacgtagtca ccttctccac tgtttaaaat tttttgatac atttctgccg tgataatgcc
     3661 gtcatcttct tcacttgcat agggtaattc tgtgagaaca ttctctaatc ccaaatcttc
     3721 tttagtaatg acgacggctc caatttttcc attaacagat aaaactgttg cttctcctgc
     3781 tattatttct tctaacccaa gaactgcgga agcatgtgtg attggaaaga attggcgttg
     3841 tacacccgtt ttttcatccg tttccatcat tcgtttagtt ttagccatta gatcacccca
     3901 actttctcaa gagtgaacac attttgcttt ggatcatcaa cggttgcgat gatcaaggct
     3961 ccttcttcaa tcgggaatgc tacagttcca actttttcga cttcatgatt atctgaaaag
     4021 agatcatcct gcaaaatatc agtcacttca atctccccgt attcaatcgt gaaaagcgtt
     4081 gctcgcaatt tctgatataa atagtccata tctgccagca aacgctctga aatagacgca
     4141 tgacgaactc cttgaatatc tactcgcgca tccgttagtt cggctaacat gactccacct
     4201 ggatcaatcg tctttaaaat atccttgatt gattcaaacc atgccaaata gtctgattct
     4261 tgtccttctc tccaatcttg gaaactgtgt tcctgttctt gtctccaacg ttcaaattct
     4321 tctttccttt cattcatcca gtccgtaaaa tcgcctttat tttcattaat aaagtccgtc
     4381 atatccgcaa ttaaatcttc gattgattgc caataagaac ccatttctcc ttctgttttt
     4441 gaaacagcat taatgacaaa ataagagaag tcttgagttg ttccaatcaa gtcttctcct
     4501 ttaaatataa tgaaattggc tgtttgtcga tgtaaacact gcatggaata tttatcaaaa
     4561 atatagttaa ttttcccttt tttagcatcc acaatttttg tttctaattg gactggatat
     4621 ttcccaccta caactgattc aaaatatacc ttacattctg ataaatcgta gggaagacca
     4681 ttttcaacta tagtcgcttc cataacctct gtattcttat tgccttgtcg aacttgaatc
     4741 atccccacgt aattataggg ttctgttgta cttaatatga cattccactt tgccattaaa
     4801 tcacctccct attttggtgg tatgacaatg gaagaaattg cacttgcact ataatactg
//
LOCUS       DADVXE010000124         4781 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.128, whole genome shotgun sequence.
ACCESSION   DADVXE010000124 DADVXE010000000
VERSION     DADVXE010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4781
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.128"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(207..1169)
                     /locus_tag="KB913_002791"
     CDS             complement(207..1169)
                     /locus_tag="KB913_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6821076.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="KB913_002792"
     CDS             complement(1171..2610)
                     /locus_tag="KB913_002792"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBB6821077.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="KB913_002793"
     CDS             2795..4741
                     /locus_tag="KB913_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBB6821078.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1520 a          820 c          790 g         1651 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaggc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa a
//
LOCUS       DADVXE010000125         4770 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.129, whole genome shotgun sequence.
ACCESSION   DADVXE010000125 DADVXE010000000
VERSION     DADVXE010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.129"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(82..1890)
                     /gene="pepF"
                     /locus_tag="KB913_002794"
     CDS             complement(82..1890)
                     /gene="pepF"
                     /locus_tag="KB913_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBB6821079.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2066..3064)
                     /locus_tag="KB913_002795"
     CDS             complement(2066..3064)
                     /locus_tag="KB913_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBB6821080.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3290..3943)
                     /locus_tag="KB913_002796"
     CDS             complement(3290..3943)
                     /locus_tag="KB913_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBB6821081.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="KB913_002797"
     CDS             complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="KB913_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBB6821082.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1401 a         1003 c          743 g         1623 t
ORIGIN      
        1 taaaaaaata cgtcgactcc cttacaagag agccgacgta tttttttcgt ttctattcga
       61 gaaaatcaaa aatagaaagc cttataaacg atcgatcaat tcttctaatt catttagacg
      121 ttgttcaaac atcgacattg catcttcaat atatgcagcc tgtgtcatat caactcctgc
      181 ttttttcatt acttccacag gataatcgct gttacctgct tttaggtaag ccaagtagtt
      241 ctctagtgcc tctggttcct ggtttagtat tttcttcgcc agtgctgaag cagcagaaaa
      301 gccagtcgag tattggaaaa catagtaatt ataataaaaa tgcggtatcc gtgaccattc
      361 gaatttaatt tctgggtctt cttcgactgc tggaccataa tattttgcat tcaatttacc
      421 ataactatca cttaggtatt cactagtcaa tggcacacct ttttcatctt ccgtatgcat
      481 gaaatgctcg aattcagcga attgtgtctg gcggaaaact gttcctttaa acccatccaa
      541 gtaatggttg agtacataag cccgtacacg agggtctttt tctgtttcca ataaatactc
      601 cgttaggata ttttcattcg ttgtcgaagc aatttctgct aaaaagatgg agtagtcgcc
      661 gtacacataa ggctggttcg aacgagtgaa ataactatga acactatgtc ccatttcgtg
      721 gacaagcgta aatagctgat ccagcgtatc atgccaattc aataaaatat atggatttgt
      781 gtcatagctt cccgaagaat aagcaccgct tcgtttccct ttattttcga caacatcgat
      841 ccaacgttca gagaatgctt tttctacgat ggccatgtat tcttcaccca ttggtttcag
      901 tgcttctaaa gctttttctt ttgcttcttc gtacgtaaag gtaattggag cttcccctaa
      961 gaccggtgta taaagatcat acatgtgcag tttttccact tctaataaac gtttccgtaa
     1021 ttccatgtat cgatgtaaca aaggcaaatg cttgtttacc acgtctacca aagtatcgta
     1081 tacactttca ggaatatgat tattgctcaa agacgcttct ctggcagagc tgtaattacg
     1141 gactttcgct ttaaaattat gtccttttat atgtgtgcct aaagtagaag caaatgtatt
     1201 tctaaattgt tcgtaaacac tgtacaaccc cttaaatgct gcttcgcgca cccttcgatc
     1261 cgtgctttct agcaactgac catacacgcc atgagataat tggactattt caccattttc
     1321 tccttcaatc gttggaaaaa ctagatctgc attattcaaa acagcaaatg tatcacttga
     1381 agcatcaaag atttcacctg ctccagcaag aagagattcc tgctcagcag ataagacatg
     1441 ggctcgatta tctactattt gctggatata atggcgatag acttccaatt ttggttcttc
     1501 tttgaaatat tgccaaatct ggtcatctga caattgcaat atttctggtt caaaccagga
     1561 aacggcttca ctaactttcg aaaacagact gcttgctctt gcataaagcg cttggtaatc
     1621 tgtatttcca gtgtcttgat cgtttttaag gtgcgcatat acataaatga cttcagtttg
     1681 gcgataaacc ctcaatacga attcaatcgc atttaaaaat tgagaagcgc cttgatcaag
     1741 tgttcctttg tgtttttcag attgttttaa ctcttctgat aattccaaat atttctcatc
     1801 aaactcttgg tcgcttgaaa agatcttggt caagtcccaa gttaaatttt caggcaattc
     1861 ttctcgtttt ggcaactgct ttacttccat gaaatccact ccttttcttc ccttagctct
     1921 atctatcaaa atagatcata gtctaacatc cacatgtcac agcatctaac ttttctactc
     1981 attcatgtgt ctgcttccat caattttagc ataactaaat cttgttttac atagaaaacc
     2041 gattcctagc ctatttttat acttactatt ttttcaaaga agacaagtgt atgcattcgt
     2101 taaaaaactg ctgatagacc atctcttcat caatcatagg aaaaagccat tcccttttat
     2161 gttcttttat ttggcaaagc catgagttga aatcaggaac tttctggttt tccaaggctt
     2221 cttcgtacaa cattcgataa agaaaaacct gttcttgtaa ataaaagaaa aaccgacttt
     2281 tttgatagat ccacgatgat agatgcaaaa gatgtttatg acgcaagtag cattgttctt
     2341 gtatggatac tgtattcttt tgcttgtgaa taagttggcg tgtcagccat ttcttcccat
     2401 cttcactcac tttttctatt tttttcattt ggttcatttt aatttcgtta ctagtgaata
     2461 tttctttaag gtccctacta gaaaaagtcc agcagctact gcaaaaggaa atatgccctg
     2521 atacagtctc tgtaatatga tgatacaaat aaagcttttg tttcttgaga tcagctttcc
     2581 agcaatgcac tcctcttttt ctattatagt agcagcaact tttttctatc aatgagaatt
     2641 gcgattgtcc aagaaaagaa ttaccaagta tccaccatac ttggtaactg ttattcaaat
     2701 aattttgggt tctttcaata aatctctggt gagacagtct agaacattgg atttctattg
     2761 ctagattcgc caacaaaata tccggccttt gccgcaacct cggcaaatag gcttccaaaa
     2821 atactggttc tactgactgt cccagccaat ccatgaagca ttcctttaac tgtaagtgct
     2881 cttttgattc tctttcacta aagaccgaac agttatctga tttttgatgg gcaaaatgag
     2941 cacatttttt ctttcccttt ttcaaaatca ctctttttcg acagccacga caataatatt
     3001 tctttccttt ttctgcatgt ttagcaaaac agcacttatt atattcattc attgcaagca
     3061 gcatttttct ccctctgaac ttatttacgt ctaagaattt atttacacga aaaaagaggg
     3121 cgtgaaaaag ctattctgca tcaagtaata agaacagcta aacaaaaata gttcccaata
     3181 tttttcgttt ggttgggctt gttaccgcag atgcaagctt ttgaacacat ttatacgaaa
     3241 aaaagactgc gacacaattt ttgtcacagt ctcttactat aatgctgatt tatacaaaat
     3301 aaaatttcgt tcgctcgata gcattacgcg ccatcagaca ttgtccatat tcattcaatg
     3361 tttctggtgt acgatcgctc ttttcagcaa actccaaaat tcgagcaatc tgattctcta
     3421 catccgcttg gttgagattt tccatccaga agtgaacgac taggtaatag cgctcttcga
     3481 ataaatacaa atcagtccaa gcagactcta gttcgacatc tgttgcaagt tggatcactt
     3541 gttcaaaatc ttcaaaagca aaagttgctt gtctttcctg ttcttctagg gcgcttccag
     3601 ataattcttc ctccggatcg ctgccaataa tctgctgacg aagaaagtca ctcacatctt
     3661 ctgaatcaac agtagaatct tctgattgag aaatttcttc atccggaaga tttttactga
     3721 taaacagttc taatccgtct ccttttggca aaacttggaa agtgacagct tcgcttcctc
     3781 ggaactcctc ttcgatatca acttcttcca aaatactata aaagaaattt tcgatttctt
     3841 tgtgattgcc aagtaaatcc aaaaatgaaa cgccccgttc ctctaaatct tcatgaccaa
     3901 ttagtacacg gatcgtattt tcattaatat gttccatttc cattttgcta cacctcactt
     3961 tgccacaatg tttaatatag attcattgta gcgaaatcag cttaaatgta aagaaaaaaa
     4021 atctcgctgt taagcgaatt taataaaacc agcggatttt tcaacctttc aagctatctt
     4081 atttaactat aacatttttg gcagacgaat actatatagc cgacttttca gctaattttc
     4141 cctctctatt tttcgtgcaa tcatcatctt ctactacctt tttatacatc taatcaagaa
     4201 tactttttgt aaaaacaaaa aaacttggaa aaactatctt tgtaatagtc ttttccaagt
     4261 ttcgtattat ccttctataa tccagccatc aattgtgctt gacgtaattc taattgtcgt
     4321 acatcgcgcg gtaggaaccg acgaatttca tcttcattaa aaccaacttg cagacgttta
     4381 tcatcaatca tgattggacg gcgaagcaat ccaggattgt tttgcacaag ttccaataat
     4441 tcttgtaacg gcagatcatc taaatccatg ttcagttttt ggaatacttt ggaacgtgtc
     4501 gagatgattt cttctgttcc gtcttctgtc atttgtaaaa tcgcttttaa ttcagaactg
     4561 ttcaatggtt ctgaaaaaat attacgttca acaaatggaa tctgatgttc ttgcaaccac
     4621 gcacgagcct ttctgcagga agtacaactt ggggaagtat ataatgttaa caacgtgcac
     4681 cactcctttt cgtgataaga atcacttttt tgtaacagaa gatcataata atctcccatc
     4741 tgtttctatt atacataatc aacttttaaa
//
LOCUS       DADVXE010000126         4759 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.130, whole genome shotgun sequence.
ACCESSION   DADVXE010000126 DADVXE010000000
VERSION     DADVXE010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.130"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            175..519
                     /locus_tag="KB913_002798"
     CDS             175..519
                     /locus_tag="KB913_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBB6821083.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            520..939
                     /locus_tag="KB913_002799"
     CDS             520..939
                     /locus_tag="KB913_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBB6821084.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1031..1381)
                     /locus_tag="KB913_002800"
     CDS             complement(1031..1381)
                     /locus_tag="KB913_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821085.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1347..2678)
                     /locus_tag="KB913_002801"
     CDS             complement(1347..2678)
                     /locus_tag="KB913_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBB6821086.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2934..3500
                     /locus_tag="KB913_002802"
     CDS             2934..3500
                     /locus_tag="KB913_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6821087.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3645..3732
                     /locus_tag="KB913_002803"
     tRNA            3645..3732
                     /locus_tag="KB913_002803"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3677..3679,aa:Ser,seq:cga)
     gene            4066..4632
                     /locus_tag="KB913_002804"
                     /pseudo
     CDS             4066..4632
                     /locus_tag="KB913_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
BASE COUNT         1739 a          797 c          910 g         1313 t
ORIGIN      
        1 aaaataaaaa aagcgttagc aactatgctt aaaaagcata tcgactgaat aaactaagca
       61 ttggacaggc tgaaagacta catttaaaat gaaatgcgaa gaaacaatag aaaataaagt
      121 tgccttagaa ccatagttga atcacctaac agtcgtgaag ggagaataag agaaatggca
      181 gaaaaacaaa ccgcaggacg agatcaatta ggagattttg caccaaaatt tgcagaattg
      241 aatgatgatg ttttatttgg acaagtatgg tccagagaag aattatctgc tcatcagcgt
      301 agtatcatca ccatatctgc attaatttca ggaggaaatt ttgaacaatt gccagctcat
      361 ctgaagattg gcaagcaaaa tggcattact agtgaagaaa tagcagaaat cattacccat
      421 ttagcttttt atgtaggatg gccaaaagct tggtcagctt ttagtttagc aaaagaaatc
      481 tatttagaag aaaatagcga agataagaaa gaggcgtaaa tgacgacaaa acacgaagaa
      541 atacacaatg gcgtgatttt tccagcaggt gaaaaaaacg aagcttacgc tcaagtattt
      601 accgggcaaa gctatctgaa tatgttagtg aatgatcccg aagtttctgt tggtgtaggt
      661 aatgtaattt ttgaaccagg ttgtcgcaat cactggcatg tccataaaga cggctatcaa
      721 atcttacttg tgaccggagg agaaggctgg tatcaggaag aaggaaagcc agcaagacga
      781 ttaatggctg gagatgtcgt cgtaacgcac aaagggatta aacattggca tggtgcgaca
      841 aaagacagtt ggtttgaaca tttggcgatc actgctggta attcagagtt tttagaacct
      901 gtaacagatg aagtgtatga aggattggaa aatcaataat gtcaagcttg aacagctcct
      961 gaaagtagat tttaatcgaa ctttcaggag ctgctttttt gattcagtct tttataaata
     1021 gaaaataggg ttaataatag gaatgagaag cacgtcgaaa gatcttaata ttgataatcg
     1081 gctgggcata catgatttcc acgtcatcaa tcaaactacc taacagatga taatcttccc
     1141 gatcatgtcg gggattacct aatagttctt gatagtagat ttccatacta gggtcccgag
     1201 gattgttcag caaatcagca agtacatcta aatcttctgg ctgagtttct gccgtaccct
     1261 gtatctctat gaaaagccct tcctcagcaa attctactcc aatacgtatt tcagttattt
     1321 catgggaata taaataagta agaagctcat cgatgattct ttttgataat tctttttcca
     1381 agtgtctttt tttcctttct gacagcggta aagttatcta gtatcggtac aaggatacct
     1441 gcaacgaaac cagttgaaaa accactgtta tatagattta gtcctccgtg caaagtgctg
     1501 acgttatgga caagagcaat atgtagtaca ccagctatta caccgtaaaa actgccgtaa
     1561 aaaccgctta tgggcgcgag acctgtccca aacacagctg caacaagcat gccagtactg
     1621 gtgatctcat gaaaagttcc aaacaaagaa gcaataaata ttccgactag tatcggaaaa
     1681 ctgtttttta aatgacaacc aaaagcactg aaacccaccg cagataaaat agcaccgatg
     1741 acaggtccat ttaactgacc gccaaccagc aaaacataag aagacagcat cagaccaact
     1801 aagcctatgt tgatcaaagt agcaccaata ccagaattag caatgaaatc agttgtcaat
     1861 tttccagatg aatcgaaaat ttctcgaatc cccaaaagcc gaaaggaatt ataatagaaa
     1921 ccaattccga ctgtcagcga aaaaaagcca aaaataatcc aaatgagagg aaagtgatat
     1981 tcattgaaaa ccaatgtatt ttcgacgatt gaatagctga ataacctcaa aacagcagta
     2041 aaagtcatcg caatcaaccc agaggtgaat ccaatattat aaagtgtgaa tccacgatgg
     2101 aaaactaaag tttgagcagc taagggcgga agaagtagac caattgctat gccagctaaa
     2161 ttccccaata aaatacctat cagtaaagga aaacgcatac caaaagtgat ataactaacg
     2221 accggtgata atgcgctacc aaacagtccg atcatgatgt actgagaaaa aggtttattg
     2281 acaaatacag cgtatagata cacacctaaa atgattgaga tagaattata aaggtttttg
     2341 ccaaaaaaag agaaaccggt aactgttaga atcgaagcaa ataagggacc gtttaaaatc
     2401 accttgtgcc gataagctaa aagcacagaa agtaaggtca aaatccctac atttatgaat
     2461 gcgcttccga aaccgcctaa agcaaaataa tctgtcaaaa gattgcttgg cgaggtaaga
     2521 atagttagca atccactcca attatcagta ggagtattag aaagcaagcc aataaaaaga
     2581 aaaaaaacac ctgtaaaacc aagataaaaa tactttcttt tctgtgaaac gattcgtttt
     2641 tgaggatgaa tataaataac gtcagtttcg ttttccatta cacaccttct ttttcatttt
     2701 ctttaactat aacttgaaat gaaagatttg gacaactatc atttaggtca aaactaaaaa
     2761 tgtaagggaa cccattgaat ttaaccaaat ttttttaatt ttgcaaaaaa aagttaaaga
     2821 agactgaaaa aaaatttaaa atataacgtt ttgagtaaaa tgtttgcaaa aaatgctaaa
     2881 aatagggtac aataaaacaa catatactgc agtaaagaag tgggggagtt ttaatgagaa
     2941 gaaaagtcta taccaaggat caaattctaa aagctgctta tgatgttgtt gcaaaggaag
     3001 ggtttaaagg atttactgcg agaaatattg ctaaaaagat ggggatttcg acacagccga
     3061 tttatctgga attcaaaaac atggaagatt taaaaaatac gttgctggat tctatctttg
     3121 aacaactaaa agaagatgtt ttccctattg aacgtactgg tgataaaatc attgatctcg
     3181 gtttgaacta tatctacttt gcaaaaaagc atcatagtct ttacatggca ttgtacattg
     3241 atgaacatgg ggacggaaag aaaatgcatg atttttcata caattatttc cgtgaaatag
     3301 ttaaagaaga tgaaagatac aatcaattat cggatgaata tgtcgatgct ctgcatactg
     3361 gtacatgggt agcagtgact ggcttagcgt cattgatgtc atcaaacatc atgcatccaa
     3421 cagaagaaca aatcattgca ctgatcaaac ggacaattga ctcgatttta gcattagata
     3481 atcctgaaat aatcagatag tgttctatca gtatgaattt gatcggtaag tccgttggct
     3541 gcaaactgtc aatggacttt tttgctaaaa aaagcgattt ctgttattta tctattagaa
     3601 ataggcttga catttcgtga aaaaagttta aaaatagtac ttacggaagg ttggcagagt
     3661 ggtaatgcac cggactcgaa atccggcgaa ccggctaata ccggcgcgca ggttcaaatc
     3721 ctgtaccttc cttatatcaa cgattagagg ttgtgaagaa gctgtcctgc atcaagtaat
     3781 aagaacggcc aaacaaaaat agcttttcct attttttcgt ttgattgggc ttattaccgc
     3841 agatgcaagc ttttgaacac cgtttgttcg gaataagggg ctgtgacaag acttttgtca
     3901 cagcccctta ttgttgtact tttaacctac aatatttttt gattccccct gagtactatt
     3961 ttttataaat gctagtaaat caatcttctt tggccttttt ttgataaaaa aaatactaga
     4021 tgtaagataa aagtgtaaaa acgatttgtt ttaggagggg aaacgatgtg taccgcaatc
     4081 acttatgcaa cgaaagacca ttattttgga aggaattttg attatgagat gtcttataat
     4141 gaagtggtca ctattactcc aagaaattat cgtttcgatt ttagaaaggt aaaaaattta
     4201 gataaacatt atgcaatgat aggaatagca gctggggtat ccaactatcc actctattat
     4261 gaggctacaa atgaaaaagg gttgagtatg gcaggactga attttcctgg caatgctgat
     4321 tataaagaat tacaagaagg aaaagataac gttgcaccat ttgagtttat tccatggata
     4381 ctagggcaat gctcaaccat agacgaagct aaagaattat tggctactat caatctagtc
     4441 aatatcgatt ttagtgaaaa actacccttg tcacctttac actggttatt agctgataaa
     4501 gaaaaatcga tagtaattga aagtatgaaa gatggacttc atttatatga taatcctgtc
     4561 ggtgtgttga caaataatcc gccatttgat tatcaattat ttaatctgaa caattatcgc
     4621 tcgctatcaa atggaacgag agtataaaat attttgtgta aatgaaaaaa tccatacaaa
     4681 aaaggaagtc ccttctgtag aataaagtta acgacaacca attcacagaa aagaggactt
     4741 ccctatgaat gattttact
//
LOCUS       DADVXE010000127         4745 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.131, whole genome shotgun sequence.
ACCESSION   DADVXE010000127 DADVXE010000000
VERSION     DADVXE010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4745
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.131"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(95..310)
                     /locus_tag="KB913_002805"
     CDS             complement(95..310)
                     /locus_tag="KB913_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821088.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIESIKYFV"
     gene            complement(320..1135)
                     /locus_tag="KB913_002806"
     CDS             complement(320..1135)
                     /locus_tag="KB913_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6821089.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1397..1840)
                     /locus_tag="KB913_002807"
     CDS             complement(1397..1840)
                     /locus_tag="KB913_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBB6821090.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1974..2312)
                     /locus_tag="KB913_002808"
     CDS             complement(1974..2312)
                     /locus_tag="KB913_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6821091.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2300..2677)
                     /locus_tag="KB913_002809"
     CDS             complement(2300..2677)
                     /locus_tag="KB913_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6821092.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2901..4094
                     /locus_tag="KB913_002810"
     CDS             2901..4094
                     /locus_tag="KB913_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6821093.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4260..4682)
                     /locus_tag="KB913_002811"
     CDS             complement(4260..4682)
                     /locus_tag="KB913_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6821094.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
BASE COUNT         1382 a          902 c          833 g         1628 t
ORIGIN      
        1 aaatcattca tagggaagtc ctcttttctg tgaattggtt gtcgttaact ttattctaca
       61 gaagggactt ccttttttgt atggattttt tcatttacac aaaatatttt atactctcga
      121 tgcaacctgg accaataaaa agtaaagaaa aaataaagga aaagacattc cttccatcta
      181 tcgacaaaag gaacgcagct gctatataca agatattgac acaccaaaaa caaaggctac
      241 ttgccaatga ttgatacaac caataaaaga attccatata aacatttttg tcaaaacgct
      301 gctctttcat aatcacctcc tattccttca ttcctgatga agcgatccct tctacaaaat
      361 atttttgcat cgctaaaaat ataaaagcaa caggaagaac agaaacaact gaggcagcca
      421 tgattaatgc gtactctgca tcaaatagcc caataaacat tttcaaccct aactggattg
      481 ttttattttc cgtagaagac aaataaatga atggccccat ataatcgttc catgtattaa
      541 cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc
      601 gatagattcc ccactctgat aagccatcga tccgcgcact ctcacataaa gaatctggga
      661 tactactgta gtattgcttc aacaagaaca caccaaaagc attgaacgct tgtaatagca
      721 ccaacgacca caacgtatat gttaaaccca cttttctcat cataatgaac tgcgggatca
      781 tataagactg ccaagggaca gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc
      841 ctttaaaatt tagtttagaa aacccgtaag cagcaaaact agaagtaaac aactgaatca
      901 acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag
      961 accaaataac cagataattc tctaaatgcc aagttttagg gatccattga atcggaatcg
     1021 tgaacacttc attatttgct ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg
     1081 tcaataaagc taatacaatc agcagaatca tacccaacca ttgaataaag ggcatgtttt
     1141 ttgaacgaat ttttgctttt tttctttcat ttcgaacacc tccaaagtta taatcttcat
     1201 ttctttgtaa tgattacaat ccagaacaac ggttattata gctgattcat ttccgttctt
     1261 cttatgtttg taagcgctta tttaacaagt tatgtaaatc tctttatttt ttttgattta
     1321 aaaatgaaaa aatacaaaag caagactgtc atacgtctcg cttttgtatt gaaatttctt
     1381 cgattagaga tacttattac tgttcaaaag cttctttgaa acggtgaatc aattcattga
     1441 ctacaggtga taaaatccga ttctttttcc agactagcat gcagttcgtt tcaatcattg
     1501 ggtcaagcgg aacgaatgtc actcgctttg aaagatgact tacagcacct tctatgacta
     1561 aagcagcacc tacctgattc tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc
     1621 ctgtgatcag caactgctcc ttttttatgc ctaaccagtc agcaaacatt cgctgtattt
     1681 ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt
     1741 tttttgctaa aacagaattt tctaaaatga gcaatcccca tttttccttt cttggtaaca
     1801 aaatcgtttc gtatttctct gtatctactg gatctagcaa aatcgctaaa tctaacaggc
     1861 ttttttctag tcactccgtg atatcatcac ttgttccgct gtggatatga aattgaacgc
     1921 tgggataatc acggatcaac ttttctagta atagtgccaa tgtattcgaa ttatcagctt
     1981 ccacacagcc gatcgtaaat cggccgctga ataattgttt ttttctgttc tcgaattctt
     2041 gagtggtttg attcgttaaa tctaaaattt cttctgctcg gcttttttag aaaataacct
     2101 gcttctgtca agatcatttt gcggttttcg cgtacaaaca gttctgttcc tagttcctct
     2161 tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct
     2221 tgagagattg ttccttcttc tgcaattgtc caaaaatatt ttagtaagcg taactccata
     2281 gcgatgctcc ttgatttttt tacttgatac attccatttt atttctagat aacacacgat
     2341 catatttctt gatttttcct tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt
     2401 tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc
     2461 cttcgctaga taggcgaata tattcaatca aagactcgat cgataatccg gcatttcgca
     2521 tacagatcgt aaagtcgacc cattttaggt cttcttctgt ataatcacgg attccgcctt
     2581 ttgtccgatt aactggtgga atcaacccga ttcgttcata atagcgcaat gtatcggccg
     2641 aaatgccctt ttcttcactg acttgtttga tattcatctg atcactcttt ctcttaattt
     2701 cttgccactt tacttatgta ttttatttat tctacaactt taagtgtact ccaagtcaat
     2761 actcatttct attaaaacta agctggatta tctatatcgg ttgtttgtgt attatttcaa
     2821 ataaaaaagt cttgtttttt tattcttttt tggatatact tttaacaatt tagggaaatt
     2881 ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa ggtattatta tcgacatcgg
     2941 cgggaattgc tttagagaat atggatatta tgtttttagc tttttcatta tcttcaatga
     3001 ttacttcttt tcatattagt ggtacgcaag cgggtttcat ttcaacgatc actaatttgg
     3061 ggatgctcat tggaggtatt ttttttggca tcatagctga taaatatgga cgtgtgaaag
     3121 tattttctca aacggtcctt ctgttttcga ttgcttcttt attgatgtat tttgcttcaa
     3181 acatctactt ggtttatctc tttcgcttta tcgcaggtgt aggagcggga ggagaatacg
     3241 gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt
     3301 cggttgctgg tattggtgcg caggtcggtg cggctttggc tgcgatttta gctgctgtga
     3361 tcattccaac gtttggttgg aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg
     3421 tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt caaatctgta caatctgccg
     3481 aaaagaaaac caaacttagc agactgtttg aatcaaaaca tcttgcttgg caaacatgtg
     3541 gccttagtat catggtaact gtccaaattg ccggctattt tgggttaatg aattggctgc
     3601 cttcaattat gcaaaatcga ttagggcttt cggtttctgg gtcttcattg tggatggtca
     3661 gtactatttt aggcatgtct ttggggatga tgacttttgg cataatcatg gataaattgg
     3721 ggcctaaact agccttttct ttgtttttaa tttgttcatc cttatctgtc tatctacttg
     3781 tgttagccca tagccagtgg agtttggtag cagccgctgt gatagtcggc tactttatca
     3841 atggcatgta tggtggatat ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg
     3901 cgacggcgaa taatttcatt atgaaccttg gacgagctgt tggtggtttt tcttctatcg
     3961 tcatcggttt cttgatggat cattatagtt taactgccgt aatcttgttt ttgagcggta
     4021 tttacctagt cagtctgctg gtcttgacaa ctcttactgg tgttacagca ttaagggaaa
     4081 gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc
     4141 atctgcggta ataagaccag ccaaatcaaa aacatgagac actgtttccg tttggctggt
     4201 cgtattactt gatgcagggc agctttttca actgctaatt tccttctatc tggcggcgac
     4261 tattctttga cgtccgtcat ttcaaagtac tttactaata acttagcata acgaaaaact
     4321 gtggatacac tcgtatattg agcgtctgca taatcttcca aatttttctc aggatgttga
     4381 tacatgaatt caatcaaatg ataattatat gattttctgt agaaatgaag ataaataatg
     4441 tagattggga agttctcctg cttttccata gaaaagcgcc gattattctc attcttcaaa
     4501 atgaccttat caggatattt ttggaacaat tcttctaaat ctgttagata attcaagata
     4561 gacttacttg ataccttcaa ttcgttttgt agttcttcta ttgaacacca acgttctgtt
     4621 tcaagcagta aatgaatcat tttaattttc ttttgagaaa cttttgttaa aaaagtctgc
     4681 atattttctc ctcctgtatc tactttacta tactacatac aagaaaaaaa acggatacaa
     4741 atatc
//
LOCUS       DADVXE010000128         4714 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.132, whole genome shotgun sequence.
ACCESSION   DADVXE010000128 DADVXE010000000
VERSION     DADVXE010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.132"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(673..1491)
                     /locus_tag="KB913_002812"
     CDS             complement(673..1491)
                     /locus_tag="KB913_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6821095.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            1652..2341
                     /locus_tag="KB913_002813"
     CDS             1652..2341
                     /locus_tag="KB913_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBB6821096.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            2355..3857
                     /locus_tag="KB913_002814"
     CDS             2355..3857
                     /locus_tag="KB913_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6821097.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            3870..4346
                     /locus_tag="KB913_002815"
     CDS             3870..4346
                     /locus_tag="KB913_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6821098.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(4443..4553)
                     /locus_tag="KB913_002816"
                     /pseudo
     CDS             complement(4443..4553)
                     /locus_tag="KB913_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1590 a          673 c          830 g         1621 t
ORIGIN      
        1 tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat gaactaataa
       61 ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc ataaactttt
      121 aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca taacattgaa
      181 gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt cttataaaca
      241 agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt tatagaaaac
      301 attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc agtaggttcc
      361 tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt atttaagaga
      421 ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta cacgtttttc
      481 tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc aagaaccgta
      541 ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa taagctatca
      601 agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta ggtttagcta
      661 agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt tttctcttaa
      721 ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat cacaaatata
      781 aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa tggctgtttg
      841 taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta tagcaataat
      901 ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg ttttcccaga
      961 taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt gggcttgaaa
     1021 atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat tttctaaatc
     1081 aagactagta tttccactag atcccactcc aaatatatat atgttttttg attgagtgat
     1141 cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg aatagagagc
     1201 ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat gttctttttt
     1261 ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag aaaaaccaat
     1321 tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct taatatcact
     1381 catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga cttttttttc
     1441 agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca tacaaactcc
     1501 tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact cctaaatact
     1561 ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag ttgttatcca
     1621 aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt tagatcttat
     1681 ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt acaaagagga
     1741 agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag ttggtatacg
     1801 tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac caatgattgg
     1861 aattattaaa agagattatc caccagaatc tccattcatt actgccacta tgagagaagt
     1921 agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc ttagaaatcg
     1981 acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat atcctcatca
     2041 gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata aagcaggaat
     2101 agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac aagatgggcc
     2161 agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg ctgagggaag
     2221 gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag gtattgttgt
     2281 gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag cattaagtta
     2341 gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc atgttaccaa
     2401 ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta acaaatgaga
     2461 gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt ttaagtatta
     2521 tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca attggtattg
     2581 ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga gtagcttatc
     2641 tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa gatgcaacac
     2701 tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt ttacacaatc
     2761 gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca agatttattc
     2821 cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta atttggccac
     2881 caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt agtttaggaa
     2941 cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac cacaccattt
     3001 accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga tcaacaattg
     3061 ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact ggtctgttta
     3121 cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga ttaccagcag
     3181 catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat ggtgggcttt
     3241 attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt gaatatatgt
     3301 ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga ttatcttttt
     3361 attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt ttgatcgact
     3421 ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa ttaattcctt
     3481 ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc aaaaaattta
     3541 aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa gtaataaaca
     3601 aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt ggaaaagaaa
     3661 atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg aatggggaga
     3721 ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa gtgaagggtg
     3781 gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc aatcaaatat
     3841 taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag aaaaaacaag
     3901 aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta aatgatcctg
     3961 tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt tcaaaaattt
     4021 atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct attaatataa
     4081 aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt gaattacaag
     4141 gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa acctcgttgg
     4201 ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt atagttgttt
     4261 ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt gctcatggga
     4321 attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa aataagctaa
     4381 ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt ctgttcattt
     4441 ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt aaagttataa
     4501 aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt caaatataaa
     4561 atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg tttactcaac
     4621 ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga accttagcac
     4681 tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DADVXE010000129         4594 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.134, whole genome shotgun sequence.
ACCESSION   DADVXE010000129 DADVXE010000000
VERSION     DADVXE010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.134"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            190..2859
                     /locus_tag="KB913_002817"
     CDS             190..2859
                     /locus_tag="KB913_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBB6821099.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2950..3570)
                     /locus_tag="KB913_002818"
     CDS             complement(2950..3570)
                     /locus_tag="KB913_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6821100.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3684..4223
                     /locus_tag="KB913_002819"
     CDS             3684..4223
                     /locus_tag="KB913_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821101.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4220..4558
                     /locus_tag="KB913_002820"
     CDS             4220..4558
                     /locus_tag="KB913_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HBB6821102.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1424 a          790 c          860 g         1520 t
ORIGIN      
        1 aaaaattttt aagggtggga cttttgattc ctaccctttt tttgcgttta tttttgttat
       61 acgaacaaat tatgaagtta tttattctaa attttatttt tttgtgaaaa ttagactctt
      121 tttaagcaga gaaaaacaag gatatgataa actgaataca acttcataga aatttggtgg
      181 aaaataaata tgaaaaaaaa tttaaagtca ttctttagag aaaacggacg ctacgcagca
      241 gctagtttcc tgattccgtt tttgatttta gcacttgttt atctaagtat cgggatctat
      301 cctggaagca gcagaagtat tttggcaagt gatgcctttt cacagttttc taattttcat
      361 gccagcttcc gaaatgttct tcttggaaag caaagtattt tttatacatg gaatgcttct
      421 ctaggattga attatttatc tttaatttct tactatctag gcgggatctt cacgccactg
      481 gtgttctttt ttccaaacca gatgatgcca gatgcactgt atgttctgac tttgcttaag
      541 gtcggctgtg ccggattggc tttttggttt cttgcacgta cgttcaagat tcctcgctgg
      601 gggcatgttg cacttagcgt cagttacgca ttgatctcat ttatcactgc acattcggag
      661 atcatcatgt ggctggatgc atttgtttat cttccattag tgattttggg gattcatcgt
      721 gttatggatc ttaaacggcc gaaactttta tttatcagtt atttactctt gtttttatcc
      781 agtttttata tgggttttat gattggcgta ttttctttct tatattttat cgcccgtcta
      841 ttgacaaact ggtcagaata taaaaaaacg attgttcctt atggtatcac ttctttactg
      901 gcaggcggcg cttcaatgat cattgtattg ccagcagtgc tggatcttcg gtcaaatggc
      961 gaggcactga gtcagatcac tacgttgaaa acagaagcga cttcttatct ggatctaatc
     1021 atgaaaaata tgattggtgt ttatgacacg acaaaatacg gatcgattcc gttcgtttac
     1081 gcaggtctgc taccattagt cctctgtctg ttttattttg ccagtcggaa agtaccgttg
     1141 aaaaataaat ttttgtacgg cagtcttttc gccatactta tcgcaagttt ctatcttgtt
     1201 ccattgaatt tgttctggca tggtatgcat gcaccgaata tgtttttatt ccgttatgcc
     1261 tatctgttct ctttcttagt gctcctgctt gcaggaaaag gatgggaaaa gatagaacaa
     1321 gacgatcgtg ggctgttgtt aggaatcatt ttggtcgtag ctgctctctt tgcggtggca
     1381 tggggcatca aacctgaagg aagctacacc tatgtgacga tgacttcctt tgtattgaca
     1441 gtggttttct tagggattta tgcttttgct gtgggatttt atcagcataa aaaactttca
     1501 ttcaatcatc tgagtatatt gttattattg atcatgtctg ctgaagcact ggtcaatacg
     1561 aacagtatga tccatggcat tcttgatgat tggaattatg cttcccgcag tttatatact
     1621 gatccttatc ctgacttgaa agctcttgta aatgaaacaa aaaaagattc cgactcgttt
     1681 taccgcttgg aaaatctgga tccagtatct gcaaacgatt cgatcaacta tggttacagt
     1741 ggtatcagtt tgttttcttc tataagaaat cgtaattctt cctcttacct ggataaatta
     1801 ggtttccgtt caagagggac aaatttgaat atccgttata acaataatac tttgctaatg
     1861 gatgggttta caggaatcaa atataacatt tctaaaaacg aaagcacgtt cagtaaatat
     1921 ggcttccgcc aagctggtca aagtggcgac tatacactgt atcagaatgt caatgcattg
     1981 ccactagcat ttactgcacc gttgtccgtt aatgatgttg agcagccagt gacagataat
     2041 ttgaccagtc agacaaactt gatcaataca ttgtctggtt taaatgaaca gtattttaca
     2101 ttctatacac ctactttgaa gaatcagttg aatacgacga tcacaaagac aacgactggc
     2161 gtcacttact cagaaacagc agataaccag ccaaaagagc tcacttggga agtccatgtg
     2221 cctgcaaata cacaagctta cttaagtttg ttcccaacca attttgcaca attagaaagt
     2281 tctagtgcga cgatcactgt caatggtaca tcgcgaaaaa cgcaaatcaa catttctggt
     2341 caatactatg atcttggcta ttatcctcaa gagacaacag tgacatttac tgcaagtttt
     2401 tatggaacga aagaagtaag tttcatggag cctaaagtcg ttggtctaga tgttgtagcc
     2461 tatcaagccg caatgaatca gatcaaagaa aaaggtgtcg aaatggaagc cactggcaga
     2521 aaagcttctg ggactgtaaa taccgctgaa gattccatgt tggtgacaac tattccttat
     2581 gacaaaggat ggaaagctaa aattgatggg aaaccagtca aggtcagcaa tttcaaagac
     2641 gcattcttga tgataaaagt tccagcaggt aaacatactg tcactttcag ttacttgcct
     2701 gaaggattta cgataggtgc aatccttttt gtcctatgta ttgcattgtt tattctttat
     2761 gtctggtacc ttgaccgcaa tcgccccttt tatggcacga ttgatccagc aatagaagaa
     2821 aaaccgcgaa atacacacag aagaagacga agaaaataaa gaaacgatgg aatctgtgtc
     2881 actcttctat ttaaatggca aaaatttcaa tctttaaatg acaaaaacca cctgattttt
     2941 ggtggttttt tatataccta tgactaaact atctcttgct gcttcgacaa cttctacagt
     3001 gatcttatcc atttgattga ttcttaaaat ccgatcaatc tgcgcaaata aacgatgaat
     3061 aagcctaaaa tttccttttg tgatcttaat gatagttgtg atagcctcat aatcagaaaa
     3121 atcttctagc ttgatatcaa ttcctaaatc tgcccatttg tattccaaaa tatgatgtgt
     3181 ttcgtcctta ctaaggttat caaattcatg tgcaaatcct atgcgagagt aaagctgcgg
     3241 ataacgagac aatctttttt caataccagg cataccgata agaaccattg ccagatcatt
     3301 tctatcgtaa atatctctta gctgttctaa atgctgaagc tttaaacgat caatttcatc
     3361 gacaataatt aagtcaattg cttcataggt tttaggcaca ggaggatctt cttgattgta
     3421 ttttagtacc atatgcattg ctttagtcag acctattcta ctagttattg tgttaatatc
     3481 cgaactgaca cgagacatct tttcagctgg tacagtataa aaaactttat ttacacttaa
     3541 tatttcatct gttgcattta tcaagaacaa gaaaaagtct gaatattcaa aaaaaataac
     3601 ggtgtacatt tttaaaagga gatgtataat cgagatttag aaagcgtttt cctcaaaatt
     3661 taatgaatta ggaagtgatt actatgaaaa aattatttag cgcacttttt attctgttat
     3721 ttggctttat tggtattggg acttctggaa atatagttaa agctagcacg atggttgaac
     3781 aaacaagtga aatggcaaaa acttttagtc aattaacacc agaagaacaa agttacttca
     3841 aatccaaagg atttagtgat aaagatactt tttacactca aaagatagag cctcaagatc
     3901 cgaaaacacg tttttctgca aatgtattgc ggttaaccgc atctactaaa aaaattacta
     3961 atacgcaggg gcggacagaa tatattataa caagtcccaa ttcggcgatg tatcgtattt
     4021 ctacacgctt gagtttaggt agtgcaaaat catatactca aacagtaaat ctagctaatt
     4081 cttatggtta tggtggagga atgtatttta catttactgg gaaaagacaa tattacagtg
     4141 taaaattagc tatgcaagtt tataatacat ttggtgtagg gtcagtctct tgcactgcgg
     4201 gaggattgac aataggaaaa tgataatttc ttactatgtc ttaaatagaa gtgatgatga
     4261 aggactcttc gtttttcaat cattacatga ggatacgatg ctaaaagagt tttataatcg
     4321 gattaagaat aaacagatag aaacaaattt atatttttta agtgactcta tcttgccttt
     4381 tattagcaac cctaaaattc ttaacttgtt gcagacaaaa gatttgaaaa gtttaccgat
     4441 tattgtcatt gatgaggaaa ttgtaaaata tggcgcttat ctaagcgtag aagaattaga
     4501 aaaattaact aacattggaa tgagtattca ggaggataat ggggtacatg gaacatagaa
     4561 tgaatatgca cagttgagaa cggaatttga catt
//
LOCUS       DADVXE010000130         4477 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.135, whole genome shotgun sequence.
ACCESSION   DADVXE010000130 DADVXE010000000
VERSION     DADVXE010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4477
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.135"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(832..1125)
                     /locus_tag="KB913_002821"
     CDS             complement(832..1125)
                     /locus_tag="KB913_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBB6821103.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(1528..2706)
                     /locus_tag="KB913_002822"
     CDS             complement(1528..2706)
                     /locus_tag="KB913_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6821104.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(2810..3124)
                     /locus_tag="KB913_002823"
     CDS             complement(2810..3124)
                     /locus_tag="KB913_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6821105.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            3231..3446
                     /locus_tag="KB913_002824"
     CDS             3231..3446
                     /locus_tag="KB913_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821106.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(3746..3988)
                     /locus_tag="KB913_002825"
     CDS             complement(3746..3988)
                     /locus_tag="KB913_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6821107.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(3975..4403)
                     /locus_tag="KB913_002826"
     CDS             complement(3975..4403)
                     /locus_tag="KB913_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6821108.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         1418 a          841 c          663 g         1555 t
ORIGIN      
        1 ataaaaaatc atcaaataat cctttacacg ttattctaaa tttaattttt attattttat
       61 tgatgtatag aaagtttggg gctttttttc tctttttatt ctaaggttat tttagtcttg
      121 tcctttaata caaagatttt atttttaaat aaaaaatact ctttttttac gattattgaa
      181 aaaaaaagat aaaacttgat taattgaagt attgcttaaa tttggaagct atgagggaag
      241 aataaaagag ttaggacggg attatctact atttttcttt gttttaaata tttgttatct
      301 ttgaacataa aagagaaatg tgtcgactgc agtgttgtgt ccctcatcac gaataaacgg
      361 tgttcaatta gctgatcttg tattcactta aaaaatggta aagtacgagt tgctattccc
      421 cattttcaat tttctaacgc tcaggacaaa atactgtttt cacaacctca ttggaataaa
      481 agcatatata ttgtttcaag aacgaaatct tgttatcttt ttaaagggca tctgtccaaa
      541 atctaatttt aggaggtacg ttttggtatt tattcgtaca aataaaagag aattatcttt
      601 attcatgtaa cgcatccaat tgattttttc atgtacgctc ctggaacgat tttactgacg
      661 attgcttatt taactgcgaa tcgctcatta gcttttatca tagctatcca tattttgaat
      721 aacgttcttg gctttgtatt atagatacag atgacaaaaa aagttcaagt atgcggtgta
      781 gaaccaatat cgcatacttg aacttttttc aatgagtata aattaaaact tctaattttc
      841 aattcccatc atctgatatg cccgaccgtc tgaacttctt ttgaaaaagc caaatgtgat
      901 tagataacgt ctttgttcga cataatcgcc actagaaaat acgttcagca gtatcgaatt
      961 aacctctgtt tctgtataag tcactccatg gtcaaagcgt ttcaagactt ctttcaatag
     1021 gatgtatttc ttttttgttg aacttggtac ttgttttact tttccatcat tcatgaatgt
     1081 gtctaaaact ttcatctttt cttgctccgt ataagtataa accatcttct ttctcctttt
     1141 gattctaaga atactccatt tatgttagaa tattctggat tttttattaa agcggttact
     1201 cttaagaaag atattatcat agtgctcttt tttttactac tacttatagg tagatttatt
     1261 ctaatccatt attctcccct accaataatt aaagaaaaaa ctggatcagg gtgttcaaat
     1321 tacatgctaa gaaaaaagaa cccttgaata ccaagggttc tttctcagtc tgataacaat
     1381 gattaacgac ggatttcttt gatacttgtg aaaagtcgtt aaagtattga tataaaagga
     1441 tttttattac ctctgactac atattgacta atttgttaaa aaatcgtttt tcaagaatcc
     1501 tgtaatacca gtgctttcac cgttttttta actctctaaa gaactaaaag caatcagagg
     1561 ttttaccttt tcatttgacg ttaagtggcg ataaattttc gaagttgttt ggtcagtatg
     1621 gcctaagcga tctttcaaga cttcccagct acagtgttcc gctactaagc ttgccattgt
     1681 atgacgagct aaatgagtat gaaatggctt attaattcct gagcgattca cgcaccgttt
     1741 gacgtgatca tttacatact ctcgacgata aggaacacca cgtttactag aatcaagata
     1801 cacaaacaaa tatgtttctt ctataataaa cctgtaatgt tgcctcatct cacccaaagc
     1861 cttaatcaac tgttgtagct tttccataac tagaggagtt actagaactc gtctagcaga
     1921 actaactgtc ttagtagttt caattcgaaa atccttactc ttacctttaa ctgccgtttg
     1981 cttatagaac agaatttcat ttcttttgaa atctatatct ccaggctgta gagcaagcgc
     2041 ctcgctgact cggcagccag tgtaaaatag aacatggaaa agtacagaca tcggtaattc
     2101 ctcatgaaca atgccataat tcaaaaaagt tctcaattca tcgacagtaa gaaacttgtc
     2161 ctcaatatta tttatggctt cttttaaatc agttaccgtt aactgatatt ttggcattct
     2221 cacagacttc attggatttt cacttatcaa attctttctt tgacaatatt taaaaatcat
     2281 atttagaact tgaataagtg attgtaaact atttttggca tagccaacat ttgttccatt
     2341 aacgccacat tcctttaagg taaaaagcaa ttcttgaagg cactctggtg tcaaatcaga
     2401 caacttttta tcaccaatcc atcgaacaat aatttttaat tgttcctctc gcttatcata
     2461 ggttatttcc ttttgttcat ttaacgaacg gtaatattgg aaccattgct cacctacaac
     2521 actaaacttg tcattgcttg caacaatttt tttcttaagc ctttgttgtt tctccatttc
     2581 cagataagcg agttgcgcct cacgttttga attaaagcca cgtcttgttg ttcgatatgc
     2641 ttgaaagtac catgtgatcc taccagtaga actgatttgc ttcttgaatc gatctgtttt
     2701 ttccatttat tgattcctcc tattttgaag gaacccaaca agcagaaacc ctttggaaat
     2761 ctttctatct atgtcatcat tgtaccgcat cttagaaaga aaatgtaact tataaagatc
     2821 gaagtagtcg caatttttct cgatagtcat tcgaatcact ctttctcatc cattctaaaa
     2881 catcatcacg aaaatagtgt cctcgaatcc cgtaccaaca gggaggaaac tcaccaagtt
     2941 ttactaaacg gttcagtgta ctatcactta tctgaaatag tcgctttaaa tcagtatttg
     3001 ttaataccag aggtaaatga ctgactgcaa gcaatttttc cgtgtaatct tccagttttt
     3061 tttgtaaaat tgaatagaac tctatttcca gagaattaac atttgtttta acttccaact
     3121 ccatcaccct tctctctcaa aatcaaaacg accaccacgg taccccttaa aattgtaaaa
     3181 aaacactcca gtactccatc aaaacggact agaaaagagg aatttttaat atgaaacaag
     3241 gaattgcaga cataaaaata attaaagaaa ttcttgaaaa atctacggct aatgcaatag
     3301 cattcggaac aggaatcaac ttgagtacag taaaaaaact taaaagtgga gagagagctg
     3361 aagaaaaatt aaatcttgcc gatgctatta aaatcacaga atttggcatg aaaaatatgc
     3421 caaccaaaat cgaaatatgg aaatagtagt ttttctgatc tatcagctgt tttgccaaag
     3481 cacataggaa tctcacctcc ccccagtaat ggcgggccga tttggttacg gaagtatcat
     3541 tatcgtagtc gcgattctca tattaaaatt tgtcgcttaa aagctaacct tgtcatggcg
     3601 taactagaga atcaaaatct acatgtactg atagatttgc tattcatttg tcaaagagcg
     3661 ctaggctatt ttcagcctat ggaaatcctt tattttgacc cgataaaaaa cttccataga
     3721 atgaaaagga aagggaaaaa atactttaac gagttgtatc aaattcaagt atcttctcaa
     3781 tcaattttgt ttccagttgt ctacgcatat attcatctac atacataacc attccttttt
     3841 cttcttcata aactggtttc atggctaacc gtgaaatata attttgatat tttgacagaa
     3901 cgatggacat ggcaattgaa tcaccagaag ctgcggcttt gattgtcgtt agtggtatga
     3961 atggtatata tcgtttattt tgcttcatat ttgacaccca aatactttcc tagctcttcc
     4021 aaagccattt gtcgttggta ccaaacactg ccgagacttt tcccaataat atcgccaatt
     4081 tcacgatcat taagaccgat gaagaaggac ataaaaatga tttcttgtct ttgactaggt
     4141 aatgctgcaa tcgcatttgc caactcctca ttggaaataa agattttcat accaaggaca
     4201 ataaaagtac cactactatt caaatttggt tccaaataat agaactctgt acctaaccct
     4261 ttttgttcca atatttccat tgatatttgc cgttggcgaa atctagcgta cttcttttga
     4321 atatttaacg cctcattgca gactactttc ttacaaaaac tgtcaaacgt atgttgaatg
     4381 tgggtttcct ctgagtcgcc cataatattc tccccctcaa aaaattcatt caactcgttt
     4441 tacttctatc cctttccatt attactacaa tctagga
//
LOCUS       DADVXE010000131         4348 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.136, whole genome shotgun sequence.
ACCESSION   DADVXE010000131 DADVXE010000000
VERSION     DADVXE010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4348
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.136"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="KB913_002827"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="KB913_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBB6821109.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2944..3378)
                     /locus_tag="KB913_002828"
     CDS             complement(2944..3378)
                     /locus_tag="KB913_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821110.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..>4348)
                     /locus_tag="KB913_002829"
     CDS             complement(3395..>4348)
                     /locus_tag="KB913_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBB6821111.1"
                     /translation="FRANNIDKVFFKLKMNNLNVAMADRERLYNSLQNLTLYSLGDIR
                     DILILVHYFFTGKIEDLFHEPLIEYTENLSKTIEQIKIDNLLSQNYDPEIYLFLYENK
                     ILEYVKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEKNYSIIVFEKLAQTSITLGMDI
                     IEAYQSRDALIQENELAVSLPEVLKVRDSGIVYYTKEIGKTKIEHLSPLISSVVQFIG
                     LNIYKRITVKEIANYFSVSETKLRESFKNEMHITIYNYISKRKISTAKIMLKSNHTIS
                     EVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNFNNIS"
BASE COUNT         1336 a          813 c          599 g         1600 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaa
//
LOCUS       DADVXE010000132         4110 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.138, whole genome shotgun sequence.
ACCESSION   DADVXE010000132 DADVXE010000000
VERSION     DADVXE010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.138"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(219..1724)
                     /locus_tag="KB913_002830"
     CDS             complement(219..1724)
                     /locus_tag="KB913_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6821112.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDPFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1721..2407)
                     /locus_tag="KB913_002831"
     CDS             complement(1721..2407)
                     /locus_tag="KB913_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6821113.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2600..4021)
                     /gene="gndA"
                     /locus_tag="KB913_002832"
     CDS             complement(2600..4021)
                     /gene="gndA"
                     /locus_tag="KB913_002832"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBB6821114.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1133 a          864 c          696 g         1417 t
ORIGIN      
        1 aaaattccct atttttattt attattttta aacacgaata ttacagcatt ttattgtttt
       61 ttcgttcatc taaaagatac ttacatttaa ttaacggatg ttattctatt taattgttcg
      121 ctagtttttt tataatgaca tccctgaatt tctcacttgc ttgtattttg taccttattc
      181 tttgttggat atataaaaaa acaagtaaag cacatgcttt acttgtcttc tgcctttgcg
      241 ataggaataa agattctaaa aattgtccct tgccctacta cactttctgc taagatacgt
      301 cctttatagt tttcaaccag ttgtttagcg atagacaacc ccagaccatt tccacccttc
      361 gttctagctc ttgctttatc cactcgataa aaacgattga agatcttatt aaggtcttct
      421 ttgggtattc cttcgccaaa gtcctgaatc gcgatctcaa attcattcag agtggaagaa
      481 atagagatat ggacttcttt tcgtgtagtt gaatacttta ctgcgttatc caatatgata
      541 atgattaatt gttcaaagtg attacgataa atttgcaggg tcacttcttt tgtcaaatca
      601 tcatctaaag tgatcacata gtctggatat aatatcttga aattattata aacttgatag
      661 gtgacttctt ttcctttagt tgtttcattc gcataatgaa catctacttg ttctgctctt
      721 gataagtcta gcatctcttg aactaagctt ttcatacggc tgatttcttg catgctggcg
      781 cttaatgatt cttctaatat ctcaggatca tctttccccc aacgatttag cagactaaga
      841 tgcccttcaa taattgcaac aggtgtcctt aactcatgag atacgtcttc cacgaattgc
      901 tcttgttgtt caatatacaa acgcatacgg tcaagcatct cattgaatat ttcagctaaa
      961 tctgccaatt catcatttgt gtcgatttca ggcatgtgga tatctgattg cggatcttta
     1021 cgtatagtat ccattgtatc tctgagtacc ttgagtggtt ttaagaaata agaagataaa
     1081 aagaaaccta aaatactact taagatcaaa gaaacaactt ctaaaacaat aagagtcaat
     1141 aatagcttat ttcgaatatc atagaaagaa gataattcat agaagctttg cgcatagccg
     1201 atcttttctc ttgtaccttt agaatatata ggctggatag ataaaaagcc agtttttcct
     1261 tctagtgtaa cgatcgttgg aactttacgt gtagtctgaa tcaggtttcg actgttttca
     1321 tgggttttaa aaatcaagtt ctcgtccaaa tcataaacat aaagatccat tgatggctgc
     1381 cctagctcag ctataaaggg atcgatcttc attaagtttc cttcgaccag tgaagtatga
     1441 tctacgacct catctccgtc atttgtcgct ttcgtcagat tacgatacgt atttactaat
     1501 gtcagttctt catccgagtt agccaaacga gaagctactt ctgaaatcgt acgctctaca
     1561 ttgtttcttt cttttgccac aatcagattg atagatgatt tataggtaat gacagcgaaa
     1621 attgtaaaca caacgaatat gaagaaagaa ctcgcaaagg cccacttgat tgtcaaggag
     1681 ggccctttca gttctctttt ttccgatttt ttcggcttta tcacgagcgc atcacataac
     1741 ctgttccgcg tacagtttgg atatagcttt cctccccggg aacgtcaatt ttgttgcgaa
     1801 gataacgaat atatacgtcc actacgtttg tttcaacttc tgtttcgtat ccccacactt
     1861 tatttagtaa aacgtcacgt gctaatacca cgttcacgtt ttccattaaa gtaagcagca
     1921 actcgtattc tctttttgtt agttcaatta cttcatttcc gcgacgtacg acacggtttt
     1981 ctttttcgat agtcaaatcg cgataagtaa tagtagtttg tttagccaca tttttatcgc
     2041 cttcaatatc gattcgacgc aacaatgcac gaagacgtgc taataattct tcgatagcaa
     2101 atggtttgac gatgtagtca tctgctccgt ggtcaagtcc agatacacga tcgatcacag
     2161 aatctcttgc agtcatcata atgattggtg tatttttgac ttggcgtaca cgtctgcaga
     2221 cttctaaacc gttcaattct gggagcatca gatccaacaa tatggcatcc cactcattat
     2281 ttaatgccgc atctaaacca gttcggccgt tgtagtggac ttctgcgtta tacccttcat
     2341 gcttcaactc tagctcgaca aatcgtgcca agttcttttc atcttcaatg attagaatat
     2401 tgctcattta ttattttatc ctttctattc tactggcttt ttaaaaactc tatcattata
     2461 ccgataatat gcttaaaaat ctatagtcat tttatcatgg atagcaattt taaaaaagag
     2521 ctgaagtcta ctcataacaa tcgacttcag ctctttcgtc ctctttttat tttctcattt
     2581 cctaacagcc gaaagactat tattcttcat ggtaccatga gtaatggaag attccttctt
     2641 tgtcgacacg ctcataggta tgtgcgccaa agtaatcgcg ttgggcttgg attatatttg
     2701 caggcagacg ttctgctctg tatgaatcga agtaagcgat ggctgatgag aaagtcggta
     2761 caggtacgcc agcttggaca gccaaggcaa cgacgtctct gactgattgc tgatattttt
     2821 tcgtgatttc aacgaagtaa tcatctagca ataaattttc gatctcagga tttttgtcat
     2881 aggcatccgt aattttttgc aagaatcgag ctcggatgat acatccagcg cgccagattt
     2941 ttgcgatttc accaaatggc aagtcccaat caaattcttt tgaagcgaca cgtaattgag
     3001 caaatccttg ggcataactc atgattttac tgaaatacaa cgcttctcgg attttttcga
     3061 ccaattcttt tttgtctccc gtgaactcaa aatcgttcgt acgagacaaa atcttgcttg
     3121 cttgtacgcg ttcttcttta taagcagaaa tatagcgggc aaatacagat tcagtgatca
     3181 atggaagtgg cacacctaag tcaagcgcgc tttggcttgt ccatttacct gttcctttat
     3241 tcccagctgc atcaaggatc acatctacta ctggtttacc tgttccttca tcgtctttac
     3301 gtgtcagaat gtcagcagtg atttctatca aatagctgtc taattcgcct tgattccatt
     3361 ctttaaagat atcagccatt tcttctactg aaaggtttaa aatattcttc attaagtcat
     3421 aagattcagc aatcagttgc atatctccat actcaatacc gttgtgtacc attttcacat
     3481 aatgtccggc tccatttggg ccaatatatg tgacacatgg tgctccgtct tctgcttttg
     3541 cagaaatttg ctctaagatt ggtgcaacta gcgcataggc ttctttttgt ccaccaggca
     3601 tgattgaagg tccttttaaa gctccttctt caccaccgga aacgcctgta ccgataaagt
     3661 tgatgccaga gttggctaac tcttcattac gacgcatcgt atctttaaag aatgtatttc
     3721 ctccgtcaat caaaatatcg cctttatcaa ggtgaggaag taactcttgg attgttgcat
     3781 ctgttgccgg tcctgctttg accattagca agatccgacg tggtttctcg atagattcta
     3841 caaattcttc gattgtatat gttgctttga aatttttatc tgggtgttct tctactacag
     3901 cggttgtttt agcccctgta cgattgaata aagccactga atagccgcgg ctttctatgt
     3961 tcaaggctag atttttaccc ataacggcca taccgacaac gccgatttgt tgttttgaca
     4021 tatgaactcc tcctacatac gggatttctc cctaatctct tacattatag cttaacacgg
     4081 ctacattgca aactaaagaa caacatattt
//
LOCUS       DADVXE010000133         4108 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.139, whole genome shotgun sequence.
ACCESSION   DADVXE010000133 DADVXE010000000
VERSION     DADVXE010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4108
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.139"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..332
                     /locus_tag="KB913_002833"
     CDS             <1..332
                     /locus_tag="KB913_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HBB6821115.1"
                     /translation="KRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKY
                     LNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIK
                     VLLGIPA"
     gene            complement(387..743)
                     /locus_tag="KB913_002834"
                     /pseudo
     CDS             complement(387..743)
                     /locus_tag="KB913_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1003..1551)
                     /locus_tag="KB913_002835"
     CDS             complement(1003..1551)
                     /locus_tag="KB913_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821116.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1552..2409)
                     /locus_tag="KB913_002836"
     CDS             complement(1552..2409)
                     /locus_tag="KB913_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6821117.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2695..2981)
                     /locus_tag="KB913_002837"
                     /pseudo
     CDS             complement(2695..2981)
                     /locus_tag="KB913_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2971..3300)
                     /locus_tag="KB913_002838"
     CDS             complement(2971..3300)
                     /locus_tag="KB913_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6821118.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(3377..3649)
                     /locus_tag="KB913_002839"
     CDS             complement(3377..3649)
                     /locus_tag="KB913_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBB6821119.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3649..3912)
                     /locus_tag="KB913_002840"
     CDS             complement(3649..3912)
                     /locus_tag="KB913_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6821120.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT         1227 a          828 c          547 g         1506 t
ORIGIN      
        1 ttaagcggtt agtgaagcag tttgatgaac cgaaggttgt agtcacagat aaagccccct
       61 ctattacaag tgcctttaag aaactaaaag aatacggctt ttatcaaggg acagaacatc
      121 gtaccattaa atacctgaat aatttgattg aacaagacca tcgtccagta aagagacgca
      181 ataaattcta tcgaagttta cgcactgcct ctaccacgat taaaggcatg gaagccattc
      241 gaggattata taagaaaacc cgaaaagaag gcactctctt cgggttttcg gtctgtactg
      301 aaatcaaggt attattggga atcccagctt aaatcataga taccgtaagg gattttattc
      361 tttatttaaa actttgcaac agaaccatta aatgttctta ctgcctcttc cacactaatt
      421 tcttcgttca atttcactaa taatacttga tctcgcttat tataatcgct ttcatttatc
      481 ctaagagtca aatctttttc caccataact tttacaccca ataaattttg cggtttattt
      541 ttctctgttg aaattctttg tgtagccttt aaactgacaa ttagctcatt gggtacatac
      601 tctatttgag agtcatctaa ttggctcata atcctttctt tttggttagt atctgcagtt
      661 acttgtttag tatgagccat gaacccaaac atactcaccc caacaaccaa tcctaaatat
      721 attttctttt taaacttttt catctacatc tcctcctaat agttttattt tagagttagc
      781 tctattactt atttactaac tcaacaacag attatcatac acttgttaat gaaatcacaa
      841 tatctcatta aaacacaccc taaaatcata accgttccta tgctcatttt ttggattttt
      901 taatcacgta accagaaaaa taaatcccct ctatttcacg caaatcaaag aagaactaag
      961 taactaccgt ttaaaggtag ttacttagtt cttctttgat tattatctaa ctttattatt
     1021 cattccccac cctttgcgca gtgagtcttc ggtatcttgt tttatctgac tggtagttct
     1081 tattatttct ccacgatcat ctaattctgg aacaattgga tatttttctc tgaacaagtc
     1141 tagttctttc accacgtcat taaacaaatc ttgcttatct tcttgcgtaa gattctgttt
     1201 aatatactca tctaaagctt ttctaagcaa ttcatctctt gtcatattag tctcatactt
     1261 ttctactaaa actctggaag tcgcatttaa caaagtcgac agttttaaag gatgcttggt
     1321 ggaataaacc ttatcaaact ttctgattgg tgcgccaact ttttttgttc ttcctctact
     1381 ctgtctttca acattggagg aagtttttat ttcttgaact tggtgcactt ctaattgctt
     1441 attttcagat ggtgtaattg cttgctgctt tttctttgct tctgcttctt tttttatttt
     1501 ggcgagtcct ttgttgttcc caaaaatatc aagtcctttg atgtcagcca attactccac
     1561 ctccgcatac caattctcgt gttcttccaa ttctttcaaa atactgataa ataattcgtg
     1621 gcttttgcga tcccattgtt ttaagagacc tttctttgtc ttctccatcg taatacctga
     1681 tccgtcgtat cgttttaagc gcgcattttt gagtacaaca tttttaatca aatgttcccc
     1741 ataaatctct tgggcttgtt tatacatttc ctgatctact gcgtcaccgc tttccaacat
     1801 gaaaggaata acaccagcaa catataaatt tgtatcaaat tctttcacaa aaaagtccat
     1861 atactcaaga tattgcatcg catttctcat cgattttact tgggtctgta agacgacgat
     1921 tgcccaatcc gcaatgtaca tcgcggattt actatataca gaaatagaag gtgggacatc
     1981 taaatagatg acgtcaaact catcaaataa tggttctagc ttttctttca tatatttgaa
     2041 ttgggataat gaatcattat attggtcttt gatccaatca tcatacattt caaaggacat
     2101 gtctgctgga agtatataga ggttattgat tactttatag acagcctctt taggtggaag
     2161 attgtttatc aacacgtcag tcacagtatt ttcgtaaaca atcggttcac cttctccgcc
     2221 tccttcttcg ttagtgaagt tcatatgcgt taagttcatc acatcagaag tatttccttg
     2281 catatccaag tcaattatca aggttctttt tccttcatta actgctgatt caaaccctaa
     2341 catttgcgcg cacgtacttt tacctacgcc acctttaaaa ttaccgatta catatttctt
     2401 cgctaccacg ttcctacctc ttttctttta gcaatattca tttgatacta ttataacata
     2461 tttattttta gttactacca aaaaaaagat atatatgtac taccttataa ttaataagta
     2521 aaaggtagta cataaataag gaaaagctga aatatattga tttatagctt tcctcaaagt
     2581 aatgacgtta tttaatttat cgagaagcag agaatactcg cgactttagt catgtagacg
     2641 aatcagattt tcgataaaaa agaagccgtc cttcttaaga acgacaacaa atcactagat
     2701 taattttttc aactgttcat aaaagttttc atgcgttcca cataacaata ctggaataac
     2761 cttgttttct ataatctcgt aagctactct atatgttgtg cccgcatatt tgaacccact
     2821 agaccaaata cctgataaat ccccagtttt ttgttcaccc ttatatggat caatcgcaat
     2881 ttcatcataa attaaattca aaaatttttc tttcaatggc ttctctttta gctttttaaa
     2941 tacttaatga catgttttga aggaacgatt tcataagcca atttctgttg ccaactcctc
     3001 tttagtcatt actttagaat tagtaagtgt atcttcagca atatctctaa aggaagaatg
     3061 cattttgttt tttctattct taaattctac aagaatctca tctttatcgt agccttctgc
     3121 aattatatca gacaaaatat cttcgctaaa atcataaaat tctttttgtg gttcaacaaa
     3181 ttcataaaga ataccattct ctaccaactt tgcttcaact tcgactccat taggaacatt
     3241 aaaatcttta ggtactgtca acatgattga attgccttgt tttcttgttt ttgtaatcat
     3301 ttaaatccct catttctaac agtatgtaat tacttagtaa atacattata ccacgagata
     3361 atgtatttac aagtaattac tgtgactcgt aatgcgtcct tgctgaataa atttcaacca
     3421 cgtgttcatc ttcatctacc ttataaacaa cccggtgttg tctattcaat cttctagaat
     3481 acctaccttc atgtgtaggt tttaacttct caaatgattg ggtagggaga tagggatctt
     3541 cctttaaagt ctgaataacc ttctcaaatt gaggtttcaa attagactgt ttgattttct
     3601 ttaaatcagc tttagccgag tttttaatca tcacagaata gttattcatt ataagttatc
     3661 ccaatcaatt tcatcaacat tagtaaatcc actatcatct ttttctcgct tacgaacaac
     3721 acccaaagtg cctatttgct caagtaatag cgtttctttg attgctttcc aatcatccaa
     3781 accaataagc accgcattat tttcactgcg ctcactaatg atttcaattt ccgtatgatt
     3841 ctcatttaca tctttcaaca acttataaaa atttttccgt gctgagctag gatttaagac
     3901 tgtttttgcc atatctactc cccctctaat ttatatctcc attctaacgt acttaattaa
     3961 gtacgtaaat tcgattgttt tgtttaaatt ggagtaccaa aacagcattg taaagtgtta
     4021 tccgtttcct ttatacccgt ggtgctagtt aattttttcc tagaggaaaa tgtctaaaca
     4081 tgttggtaaa tcaacaaaaa aacgcata
//
LOCUS       DADVXE010000134         4070 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.140, whole genome shotgun sequence.
ACCESSION   DADVXE010000134 DADVXE010000000
VERSION     DADVXE010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.140"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            86..1435
                     /locus_tag="KB913_002841"
     CDS             86..1435
                     /locus_tag="KB913_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6821121.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="KB913_002842"
     CDS             complement(1563..2153)
                     /locus_tag="KB913_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBB6821122.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2300..3652
                     /gene="brnQ"
                     /locus_tag="KB913_002843"
     CDS             2300..3652
                     /gene="brnQ"
                     /locus_tag="KB913_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBB6821123.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1176 a          744 c          789 g         1361 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta cttttaaaaa
     2281 aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc tttttatagg
     2341 ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg ttcatttggg
     2401 tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta ccggtatcgg
     2461 tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg tatatgaatt
     2521 agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt acttagttat
     2581 cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg gtttagcacc
     2641 atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg tattttttgt
     2701 gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg gaaagttcct
     2761 gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt tgaatccact
     2821 aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt ttttcacagg
     2881 gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg ggatcatcat
     2941 tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta aagacacgat
     3001 caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc tcgcttattt
     3061 aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca cgctggctca
     3121 gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta tcgttatatt
     3181 agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat tcacagattt
     3241 gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc cttgtttagc
     3301 ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga tgttcatcta
     3361 tccattagca atgacactga ttttactagt gttagttggt cctttgttta agcagcgtac
     3421 ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg atgggttgaa
     3481 cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat atgttgcgga
     3541 aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag ttatcggttt
     3601 tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt gataaaagag
     3661 gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa ttttgaaaaa tggcttctca
     3721 catttttgca taaatttgac ttaataccga gaaactgact tttgaacacc gtttattgag
     3781 aggtcgtgaa aaagccgctt agtttcaagt attaagaaat attttgtgaa aatggcttct
     3841 cacatttttg cataaatttg acttaatacc gagaaactgg cttttgaaca ccgtttattg
     3901 agcgtctata aactgacctg agtattagag aaacaaaacg gcaaagtagc tccatatact
     3961 ttgccgtttt gttttgaact aataccgaag agaagctgat caaacaacat ttcttttata
     4021 atatagattt tagacatata tatgatataa aaatagtttt cgcaaaaaaa
//
LOCUS       DADVXE010000135         4067 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.141, whole genome shotgun sequence.
ACCESSION   DADVXE010000135 DADVXE010000000
VERSION     DADVXE010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.141"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..1157)
                     /locus_tag="KB913_002844"
     CDS             complement(<1..1157)
                     /locus_tag="KB913_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6821124.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRV"
     gene            complement(1160..3409)
                     /locus_tag="KB913_002845"
     CDS             complement(1160..3409)
                     /locus_tag="KB913_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBB6821125.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            complement(3506..3961)
                     /locus_tag="KB913_002846"
                     /pseudo
     CDS             complement(3506..3961)
                     /locus_tag="KB913_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
BASE COUNT         1311 a          744 c          580 g         1432 t
ORIGIN      
        1 actctagtat tttttttatt tgtcgcaaaa aatgttacaa ataggatcac aataaatatt
       61 cctgcgaata caaaaaatgg agcagtcaaa tttgtacttc ttgttagaaa ttgtgctaat
      121 tgcatagcaa taggagctat aaaattacca atattacagc caataaaaat caatgaagta
      181 gcaaaattaa ttgtattctt tgtagtgact ttatctaagt tactaaagat aaatgggaag
      241 caccatgatc ctgttatact tgataaaaat aaacccgtta gcaggaacgt catattaccg
      301 tttgacacag caattaacaa atttgaaatt ataaagaata taattcccaa gtatagggtt
      361 ccttttccta tccacttatt tattggtcca aacataaatc ctgctagtat tcctaagata
      421 ggcattagag ctaaatagtt actagcatta aagtttaccc ctttaatttc agttgcaatt
      481 gatgcaaatc gtacagaaat agcaatacta ttcattacga gtaagattgc aaatagaact
      541 agggcaaaaa ccattggatt catcttttct tttacatgat tttcaggtat gtcactattt
      601 tcatctctaa tttcaggaac ttttagcgcg aataagagag ctacaggaaa cgcaattgca
      661 tagactaaaa acgaagccgt ccaattaatg ttcactaaaa ctccagcaag aaaaataagg
      721 attgtctgac ctaaagcttc cattgaattt ctaataccta atagcgttgc tctagtattg
      781 ccagagtata aagagctgat atatgtcaca gccaatgaat tatatactcc taaaccggca
      841 cctaatatta ctcgactaat aagaacggtt tggaaggtag ctgtaaatac tggaataatt
      901 cctcctatac cagctaataa taaacctaaa attattgtct ttttcattcc tattcttttg
      961 gcaaagtaac tagataataa gataaacaaa ataacagtta tacttggtgc agttcctaaa
     1021 agttcacttt gactttgtga tatccccaaa gactgtttca tttgtggaat aacaccatta
     1081 attgcttgag agcttgttaa cattagtgaa atacttaaga ttgctccttt ttgaagtaag
     1141 cttttttggt tattcatctc tacttttcct cctgtgttat aacccaaatc ttggaatcaa
     1201 aatcaaatgt ttctgggcgt cgattctgat catttatttg tccactagat gcatctgaac
     1261 agactagtcc tgctctcatc aattccattc cagatcgcaa actattttgt cctacattat
     1321 aaagtccgtc attatctaac ccttttaatt tcagtcggcg gtaaggagca tttacctcat
     1381 ttaatgtttt ataatgagca acaatagccg ttttcttatc atgactaaca accatccacg
     1441 cggtttgatt atcatcatcg aatggtgata atagtctata aaaagtacca ttatgaatta
     1501 tggttctata ttttttataa aaggcaattt gttcttttac aatcctcaaa tcgccttcac
     1561 ttaattcatt taagtcaagc tcatatccaa atgcaccaaa aaaagctaca tttcctctag
     1621 tttttatagg tgttatacgg tttgtttgat gatttggaac aattgataca tgagcaccaa
     1681 tagacgaaag aggatacagc atactagttc catattgaat ttttaacctt tcaattgcat
     1741 ctgaatcatc actagcccaa gcttgaggtg catagtgaag cattccagga tcaaagcgcc
     1801 caccacctga tgaacaagac tcaaatagta tgttaggata ttttgttata agtttttcat
     1861 ataagcgata tacgcctagt acatatctgt ggaatacttc tccttgttga tctgctgaca
     1921 agtgactgtc aaatacatca gtcaatggac gattcatatc ccacttaatg taatctaagt
     1981 ttgattcatc aatgatttta cacatttgat cgaaaatatt ttcaacaacc tcatctaacc
     2041 caaaatttaa tacatattgg ttcctaccat gattaggttt tcgattaggt gtagaaataa
     2101 tccaattcgg atgtgtgcga tataactcac tatccttatt caccatttca ggttcaaacc
     2161 ataaaccaaa tttcatacca aaactacgaa ttttttctga aaggctgccg attcctctag
     2221 gtagtctttt aggatttaca tgccaatctc ctaatcctgc acaatcgttt tctctttctc
     2281 caaaccagcc atcatctaat acaaataatt caataccaac atcaaatgct tttttagcaa
     2341 tatttaccaa cttttcttcg tcaaaatcaa aatatgttgc ttcccaatta ttaattaaga
     2401 caggacggtc tttttctcgc cacttaccac gagctaagcg ttttctaaat agttgatgaa
     2461 aagtttgact catggcattt aaacccttac ttgaataaac cagaatcgct tctggtgctg
     2521 taaatatttc tcctggattg agtttccaat taaatccaaa tggattgatg ccaacttgta
     2581 gtctagtaac atcccatgta tctacttctg cttgaattaa gaagtttcct gagtaaacta
     2641 gtgctgcacc aatagcttct ccttgatttt catcagtatt ttttcttttt aaagtaacaa
     2701 atgggttatg ctgatggctt gaaatacctc gagtagattc gattgattga attccttgtt
     2761 gtaaagtacg cgacttaata gttctttctc taccccaagc accagataat tgttgccatt
     2821 cataatttgc atcgggtaaa tccaatgata aactgctaat attctcgatt atttgaatat
     2881 cttttccttt attcataact cgcgcgctac gagtaataac aggataatct ctataaattg
     2941 tatataataa ttctacttga acatttgtaa ctgaatctaa aatataaact ttcaatgttt
     3001 tgctttcatc attattatca acataggtag caggtaaacc ttctagttta ggttttcctt
     3061 cttccacttc gtacccttga tagacaaaat ctgataagcg agagccattt ttctgtagta
     3121 atgaaatagc aggatgtcta aaatctgttg taccatattc aggaaattct tgttttaagt
     3181 gctctaacga atatagcaaa tcgttttcat ttctataggt tgtcataggc cgatgatgca
     3241 tctcaattag atgactatag tcattatctg gtaagttctc accataatat aaatgcaata
     3301 atttaccatc ttccgatatc ttaaaaatgt aacttatctc ctgattaaac aaatgaaatt
     3361 gttggttttc tgatcgataa ataatattca tttcattatc cttatacata agctctcctc
     3421 cgtttcttta ttgcattata aaaaacgctc acataaatag taagcgttta aagtaacgaa
     3481 tatttatcaa aatcaaatgt ttagtttatt caccattaat gattcctaga cctaatctac
     3541 gttttcgata tactcccggt gaaacaccat ttgctttctt aaaggcttta gaaaaagatt
     3601 gtactgttga gaatcctatc ttgtcactga tttgctggat tgaatattca gttgatgata
     3661 acagatcgtt tgcaatagaa attttgattt cactaatata ctcttttatt gatattccca
     3721 tatcattctt aaacaatcgt gataaataat tttcgtgtat cgatagactg acagcaatat
     3781 ctttaacaga taatttttga tacgcattct cacgtattat ttcaattgtt tgacgaacaa
     3841 aaggattcat ctttttagta attatccctt cgttcagata actagctgaa tttaagagga
     3901 gttctaaaaa tttataaact tgtttttgtc tggacaattc actgactaga ttgtcctgat
     3961 ctttcagctg agtgttaggt tctgttacta aatatataga attttccata tccaccctcc
     4021 tatgttagat ttggataatt tttgttttat tatgtttata ttattac
//
LOCUS       DADVXE010000136         3992 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.142, whole genome shotgun sequence.
ACCESSION   DADVXE010000136 DADVXE010000000
VERSION     DADVXE010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.142"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            402..734
                     /locus_tag="KB913_002847"
     CDS             402..734
                     /locus_tag="KB913_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821126.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
     gene            859..1116
                     /locus_tag="KB913_002848"
     CDS             859..1116
                     /locus_tag="KB913_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBB6821127.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            1348..1752
                     /locus_tag="KB913_002849"
     CDS             1348..1752
                     /locus_tag="KB913_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HBB6821128.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            1771..>3992
                     /locus_tag="KB913_002850"
     CDS             1771..>3992
                     /locus_tag="KB913_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6821129.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKR
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     "
BASE COUNT         1473 a          529 c          727 g         1263 t
ORIGIN      
        1 cgttatgtag taaatgtaat agtttttttg gtagtgagta tgttgaggaa tatattagat
       61 ttgcagaaga caataaaaat ttcctttata acaatacaag tttaaagaat ggtaagtctg
      121 atttaacaca ttcaataaag aaaatgaatt cacttagagt tgcaaaagca attgtaggaa
      181 tgttttttag tttaaatggg gatgaagatt caatggataa gccattctta gattcggtac
      241 gagaatatct tagcaatcct aaaagtactt tatttcctca tgaagactac aaaattataa
      301 tgaattatta tcttccaata ggtgctccac agaattctaa aatcaaaatt cctaatgaca
      361 ttgtaaatga tggtgacact cacaatgtaa taaaaggttt tctgcccctt gatctatcaa
      421 ctgggagaaa aattcgattt tcagaaattc agtatgaagg aattggtttt actcttatag
      481 atttaaaaaa ttcaactttt gaaataaaag aaggattaga tttaaaaaat ctcctttgtg
      541 cagatgataa aatcaaaaaa atacaattgt acaaagtccc tatattaaca ccaacagtac
      601 ttacaatgtt ggagatggaa aataatatta attatattga ctcaggttca gatttgctga
      661 ttaggtggca ggtaataact aattttctta tggaattaaa aaaatacagt aatactcaaa
      721 cgaagttctc ttgaagttat aaagaataca ataaatataa atttccttta gactatatta
      781 aaatcagcaa tcgaaggaaa ataaaagaag aaaatggtac gcaaaatcta actattagag
      841 caaaaacagg aagctgcttt ggaagatagt cccgaattgt ttccgatgtt aaaagatcgt
      901 ttaaatgaat tgactgaaaa acgaagacag ttacaaattc gagagaatga aatcttaggg
      961 atctttcaac aacaagggga accgattcaa gtcaaagatg tccaacagat attgactagt
     1021 ttggattgct ttcttatcca gagtgagaag aagcaagtta aagctttgta tcacaccttt
     1081 attgagaaaa tcacctttga tcctaatcag aagtagatat tgccgatccc gatgagattc
     1141 acacctactg tgatttgata attgaatgag taatatcaaa tagccgtatc caaaccaaag
     1201 gatatggcta tttttgtgtt agggatatac gtcacgtagc ttgttatcaa gaataagttt
     1261 ctttattttt ttgctttttc taaaactgag tatgctaaaa taagagggta tatagcaact
     1321 ttaaataaga gataggagtg tatctttttg ggtgcagaat taaatcagaa gttatttagt
     1381 gcggcagata atctccgtag taaaatggat gcgtcagaat ataaaaatta tttattgggg
     1441 ctgattttct ataaatattt atccgaccgt ttgttggaac aagtggttct tttagcagat
     1501 gaatccttag aggaatatga cacagtaagc aaacaaacga tgttgtatcg tgaattactt
     1561 tcagatgaag aatcaaaaga agatctgatt gcaacaatcg ttgatatttt ggggtatgcg
     1621 atttcgccag agtatctttt caacgtctta gcggatcaag caaaacaagc aacgttccaa
     1681 ttgaatgatc taaacaaagc ctttttagca agtcatattt atggaaaaat actgtcggca
     1741 aaattcgaat agtgtcgagg aggtgctgtg atggaagaat taaaagaacg cattgtcaat
     1801 tatgtcatag agaactctga gattaaaaat aaatggggga acaatacagc acagaaaata
     1861 tctgaaaaat taaatgttag tcgtaatatt gtctctcaat atttgaatga attcgtaaaa
     1921 gatggagaat ttggaaaaat caatactcgt ccagtaatct tcttttcttt accggagaaa
     1981 gttccaaatc aacaaatttt tagctcttca gaggaagcgg aaaaatggta tgatagctct
     2041 tttagggttg gaatagaaag ggttatcgga agtcaaggaa gtctgcgaaa tgtaattgct
     2101 caaattaaag cagcaatcta ctatccgcca aatggcttac ccattttact tcatggcgag
     2161 actggaactg gaaaaagcta tttagcaaat tatgtgtata aggatttgtt ggccaataat
     2221 tatatagaag agaaggcatc tttcatttca gttaattgta gtgaatatgc caataatcca
     2281 gaacttttct tgtccaattt ttttgggcat gtaaaaggtg catatacagg agccgaagat
     2341 ggaagaaagg gtttagcaga attagctaat aatggagtct tatttttaga tgaaattcat
     2401 gcattgagca atgaatgtca ggagaaactt tttcagttta tggatacgag gaaatttcat
     2461 cggatgggtg ataatgaaaa ctggtacaca tcaagttgct ggattatatt tgcaacatca
     2521 gaaccacctg aggataaact attatcaact ttgttgagaa gaatacctgt aaagctaaca
     2581 cttccaacat tagacagtcg ttctctttat gaaagaaaac agttaatcaa gatatttttt
     2641 aaatcagaag aagaaagact agcaaagaaa atactgatat ctcaacaatt attagatttt
     2701 ttattaaact atcgctttag tgaaaatgtt ggcaatttga aaaatatcat tcaattgacc
     2761 tgtgccaatg ccttttattt cttagatgat ttggaagaac tttatattca gatgtatcat
     2821 ttaccacaat gggtgaattt caacggcatg aaggttatga aaagacagaa tgaattaaaa
     2881 tatattcaaa tggatgattt ggaaaaagta gacgaagttt ttaatatcaa cgaacttata
     2941 gagtatcttt atcaaacgtg gaagaaagac actgataagc agcagctttt tgagaaatat
     3001 gatagatatt ttagacaaaa gaatgttgat atccaaaata attcagcttt aacatatccc
     3061 acctatcaag agattcgatt tagacagtat gttaaggaaa tagagagaga ttttcaaata
     3121 gaatttgact attattatct tcaaataacg tctatctttt tgaattcttg gatttatcaa
     3181 atccaattaa catcggacga taaattatat tccttcatca atgatattaa tagttggtgt
     3241 agtcgagaag ttcaattagt caatcgtttt attcaaatag gggatattta tttaacaaaa
     3301 attcaaaaaa atgttttggt tattttattt aagttaatgt gtagtaaaga atttcagcaa
     3361 aaacgtttag cactgatttt ggctcatgga gatctaacgg caacctgtat agcaagtact
     3421 gctaatagga tcgttgagag atatatatac gacgccattg atatgccact aatgacttca
     3481 agtagtgaga ttgcagacaa aattaataga tacttacaag agtgtaccgg atatgaagaa
     3541 attattttac ttgttgatat gggttcactg gagaaaattt atctaaattt ggaactagac
     3601 gctcaaaaaa aattcggact actaaacaat gtttcaacaa gaatggctat tgatgttgca
     3661 aatcagatat tattagattt accgcttaaa cagattcttg aacaagtaaa agaaaatcaa
     3721 aatgtggatt atatttatga atcatcaaat attaagaagg atatgattgt ctgttcttgt
     3781 gcaagcggat taggaacttc gtttaaatta aaaaggatac ttgaagatag ctttccaagg
     3841 gatactgatc ttgtcataga aacgtgtgac tattactctt tagtgaatga aaactattta
     3901 tcggagcttc gtaaagagaa caatattctt tttattgttg gaacactaaa tccacatcta
     3961 gaagatgtag aattcttttc aattgaagat at
//
LOCUS       DADVXE010000137         3872 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.143, whole genome shotgun sequence.
ACCESSION   DADVXE010000137 DADVXE010000000
VERSION     DADVXE010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.143"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(716..3865)
                     /locus_tag="KB913_002851"
     CDS             complement(716..3865)
                     /locus_tag="KB913_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBB6821130.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1076 a          800 c          635 g         1361 t
ORIGIN      
        1 actaatacag gtagtcctct tttttgttat tttgatattc taaatcattt tttattggat
       61 tattcccttg ttcgatatag acccaaattg atctatcaat aattatcaaa ctgagtcata
      121 tagagacaaa aatttcaaaa atgacctgtt aaatggtcat cgaatatcat ttaaaatcaa
      181 tacgacggag tcagacacgg agtcaaaaca agcccgctga gagtaaaaaa tatatacagt
      241 cccataggta aagtgccaca ggactgtata tttttttatt tgagattacc tgaaatgatt
      301 ccatttactt tttatctcat tttttcctac tagttagtat caaatactct cctattttct
      361 caataaacta ttttgggtta catggtatct gaaacagcta aaaccttgtc attacagcaa
      421 aaaatcactt tatctccgtt tcatttcaga tacatttcac ttaagcggat tccaaaaaaa
      481 caaaagaaaa aggaacccct agttagccta tgctttttat tggttcctct caaaacacgg
      541 tcatataaca acggggtggg gtaaatgaat gaaaaaggtg gaggaaacat tattcaatag
      601 ctgtcttaaa tacttcgtta taaaatgtga acaaataaaa gacatctatc cctattttct
      661 acacttccac tttactacca tctttgaatc gtacaatttt cttaactctt ctcgtttacc
      721 tcaattcatt ttcaagtgga atcagctcat catctaacat tttacgccat gctcgcttca
      781 tttcttgtgg gtatttaaat ggcttcgctt ctggatggtt ggctttatat ccttcgtaat
      841 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
      901 gattagaagc atgtaattct ttctcagaaa caaaccactc attggaaaag acatgaatca
      961 aatcatcact cgcttgtgta aaatagcgac gtttaatgac aaagatatct tcattactat
     1021 ctaaagtccc cacatcaaac gcatttaaaa tttgtcggta aacttctttg actccttctg
     1081 ttttattcaa tttagccaaa gctttttcaa tttcttctcg tgcatctgaa ctattcgccg
     1141 cataagttcc tagtaattga tcaatataag tagaatcaat atcatacaac ttcgtggtat
     1201 tttcactata aaattcgatc gtggaaaaat cttctccctc tttttctggt tcttcctcta
     1261 ttaatgaacc cttcacggtc tcgtacacgc caatttgttc ttccaaaagt tgaatttgat
     1321 tgttcaaggt tgaagatttc accatgtcat cattgtaatc gtcataagtc actaacgatt
     1381 cataagcacg attcaattct tggaatgctt tgacgtactc gatacggatt tcaagtggcg
     1441 tatgttcatc aatggattcc atggatgaaa cctcttttaa cttaccatat gcttgcttga
     1501 atcttttttt ggattcctga taacttggat aaatcaaacc cgattcttct tttgcttctg
     1561 aatacagttt tgtcgcatcc tcgacattct tctccattgt ggctggcttt cggaaagtaa
     1621 caattagtcc ttttgttttt tctggatacg tacggttcgt acgtgaaaaa gcttggatca
     1681 atcctgcata ctctagatta cgatccacaa atagggtttg aatcgtaggt gcgtcaaaac
     1741 ctgtcaatag acgatccact acgatcacta aatcaatttg tttcccaaat tgtttgaatt
     1801 ccgctctttt tcgtgccaaa cgattattga tgtctccgtt ataacgctca atgtctgcta
     1861 atgaccagga agtatcataa tactgattat attcctcaat aattttttgc atttcttctt
     1921 gttggacact tgaatctcgg ctgttttctt ctaatgaata ggtaatagcg attcgtggaa
     1981 aatcaggatc ctccatcgtt cttccttcac gaatgggctg attaggaaac tcttttgtta
     2041 accagtcagg ttctttcgtc atttctttga tcgctcgata atactttttg gccatgtcaa
     2101 tggaactcgt ggttaagatc gcagacttcg ttggacggcc atttcgaaaa tcaaattttg
     2161 tataggcatt gtctggacgg aacattttat gaatgacttt ttggatatgt tcatctgctt
     2221 caaaaacagt agggtccaaa taactttctt ttttgacagg ctccatttga tcaatcatac
     2281 gattgatctg ttccggtgaa tactctgcat atgtttctac ttcttttaat ttccgataga
     2341 ttttattctc taatgaagtc ggctccacgg tgttttcatg ctctacttga aatcctaaaa
     2401 ccgagccatc ttctaatgca ttcttgatgg tataggtatg caagacctct ccatactgat
     2461 catgggtcgt acgtgccaat tgccctttgg cttgtttccg attctcaggg aaaatcggtg
     2521 tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt tttgatttct tccatatttt
     2581 cagcacttaa cgctcgatga cactcatcta ctacaaacac gatatgttgc cccattaatt
     2641 tttggaagcg attggttcct tttttctctt cttgtttttt tgcatatttc aacgccgcat
     2701 ctagcttttg acgggttgta ataatcacaa catttgcatt ggcatctgcc aacagagttt
     2761 cacttaactc tttggcactt cctgttccca cgatcaagct attcgctttg gcgttcccgg
     2821 aagaaatccc agtattaaat tccgaagcaa atttcgtaaa ctctgtggtg gtttgattat
     2881 ctaaatcttt gcggtccact aacatgatcg tccgatcgat ccccgatttt cgtgctaaaa
     2941 gcttagtaga tacaaaacta gtcaacgttt ttcctgaacc agtcgcatgc cacacatatc
     3001 ctgattgatg tttatttgca gcaataaaca aggcttgaat cgcatgtact tgataaggat
     3061 gtaacaccat gaggatttta ttgtcttgat cttcactgac aatcgtataa tccgcaatca
     3121 agcgatgagc atccgggata tttagcactt gtttgcaaaa ctcatataag ttttctacct
     3181 ttttattatc tttcgttcgc caactaaata aaaacttagg atgcaaatcc tttggtaagg
     3241 catttgcaaa ataccgagtg gtttgttcat tggaaaccac aaacaactgt aaggtcgaaa
     3301 agatattgtt ccgaaacata ccttcttctg catatttttt gatttggtta aacgcctgat
     3361 aaaaactatc ttttgcggtt acttgtttca gctcgatttg gacaatcggt aatccattga
     3421 tcagtaaggt gacgtcaaaa cgtcgatccc gtgcttctat gttacttcca cgttttgcaa
     3481 tttgatggac cacttcatag gtagagattc ctccaccaat gtcttgatta gaataaagaa
     3541 tgagcgagac agaacccagt tgcggatctt cccgttcaat cgtgatccga gccattccat
     3601 tttcaccttt taaccatttc gcagcatcaa agggggtttt cgttcgtagt aacaattctg
     3661 ttttgatcgt ttcaaattct ttatcggtca aaggaaaatc attcagttct gcttgattat
     3721 ttgagatgat tttttggcgt aaattgaccc aaagatcttc ttctgatttt agatcgggac
     3781 gatacgtcca ctgattatgc ccttccccca atacacggat caactgttct tcgacttccg
     3841 cttcctcacg gtgactaatt ttcatttatc tt
//
LOCUS       DADVXE010000138         3848 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.144, whole genome shotgun sequence.
ACCESSION   DADVXE010000138 DADVXE010000000
VERSION     DADVXE010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.144"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..341
                     /locus_tag="KB913_002852"
     CDS             <1..341
                     /locus_tag="KB913_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821131.1"
                     /translation="FSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFLMSLKPPK
                     SISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYIGYFPNKN
                     NNFYFYRNKL"
     gene            complement(467..1144)
                     /gene="nth"
                     /locus_tag="KB913_002853"
     CDS             complement(467..1144)
                     /gene="nth"
                     /locus_tag="KB913_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBB6821132.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(1151..1849)
                     /locus_tag="KB913_002854"
     CDS             complement(1151..1849)
                     /locus_tag="KB913_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBB6821133.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2117..3301
                     /locus_tag="KB913_002855"
     CDS             2117..3301
                     /locus_tag="KB913_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBB6821134.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3307..3750)
                     /locus_tag="KB913_002856"
     CDS             complement(3307..3750)
                     /locus_tag="KB913_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6821135.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
BASE COUNT          999 a          760 c          636 g         1453 t
ORIGIN      
        1 ttttttctgt acttttaagc actactctta aaggaaaatt tatggaaaga agctctcatg
       61 caatgattct cactttttta tggttgttgt tcaccagaat ctatattttt ctgatgagcc
      121 tgaaaccgcc caaatccatt agtttatgtt tagttataaa tggtattttt ttattatcac
      181 ttatcatttt tattacacct ttagatagat acgtcactta tttatataat cctttggaat
      241 actggactta ttttataggt atattggaag gcattatttt ctacatcggg tattttccca
      301 ataaaaataa caacttttat ttttatcgca ataaattgta ataagttacc atcctagcta
      361 ctgagtatgt acatttactt tttcatgcaa aaaagataaa cgaaacagct tttctccata
      421 ataacaagat aattcataca tttatttgca attaaagaaa ccacgtctac aggcgtggtt
      481 tcttttttag cgccttttct tttagacgca tccgattttt cccatcttga catattgata
      541 gcaaaggaca tacctcgcac ttgggatttc ttgccgtgca atgatatcta ccaaaaaaaa
      601 tcagtgtatg atgtgtcttt acccataatt cttgtggtac tttccgcatc agtgtttctt
      661 ctacttccat gaccgtagca tctagtttgc agatcctcag gcgttttgag acacgttcca
      721 cgtgggtatc tactgcgatt gctggtatcc cgaatgcatc ccccaatacg acatttgctg
      781 tctttctgcc tacaccagga agagacatca attcttctct tgacgttggc acttgcccat
      841 cgaaacgttc aatcagctgc tgtgcacacg ctttgatgtt ttttgcttta tttcgataca
      901 aaccaatcgt ttttatttta agaatgattt catcgattga agcttctgct aacgcatcgg
      961 gtgtcggaaa agaggcaaac aaatctggcg ttgctttatt cactgataca tctgtcgcct
     1021 gggcacttaa gatcactgca atcaataact caaatggatt attgtgcttg agttctccat
     1081 gtgcttcggg aaacattcca tacatcgttt ctagagcttc cattgttttt tgtttgctta
     1141 acatattccg ctactcctcc aaccaatttt tcagtgagac tttcggcaat tcttcttgtt
     1201 gagctgactg ttctacttct ctttgaagaa gctgctgttt tcttcgtttt tggtcttctt
     1261 ccacttgttg ttttgtacgt agattttttc tttcccacga tagcaaaatg cggtcaacgt
     1321 aattaaaact ataagcctga tttaatacgg cttcccgcag tgctagcttc aaaatttccg
     1381 gctgataatg gtcttcttct agccattgtc cgatccgctg gaactcgatc gaagaaagcg
     1441 ggcgtccaaa ttcttgttca aataattgat acactgactg gatttctttt tcttgtgttt
     1501 tttcttcgta ttttttttct tgtgttttta aatactcacc taatagatca tagatggggt
     1561 aaagattata tcgatctgct tttttaccgt tgacaatcgt cgtttctatc ttgataaatc
     1621 catttgttac gagacgatcc agtatttgaa aaatctgatc ttgtttgatt cccatatcca
     1681 tagcaatcat ctgcaaatca gggaaagtat ctccttcaag ctgtgccata tgcaactgta
     1741 gaacaaataa aaattcttca gattgtagac cgatcctatg ataattttta agtaaaagat
     1801 tagatatgac tgtttgtcca gcgcttaagt aattttctaa attcaacatg atttctcctc
     1861 cgctcaatca cagtatacgt aaaaaaaaca tgggaagcaa gaacaggttt cttttctatt
     1921 tacttcactg atcggtcaga tttacaatgt cgtctacttg atttttgttt gttcatgttt
     1981 ttgatgcgta tcttcacttt tcggaataaa taaattaagt agatttcgct gttccttaga
     2041 atgttgacaa ggaaacaaaa ttactataca ctatttttgt ttccaagtta acattattgc
     2101 ataaaggagt ttttacatgt acagtttcac aaataaacat tctaaagttt ttggatacgt
     2161 ctctgtctta ttcactggat taggatttac tatcgtcagt cctgtacttc cgtttttaac
     2221 gctgccttat tctcactcca tacatcagca agctttctat atcactttgc tcatgtctgt
     2281 ttatgctcta gctgccttct tatctgcccc cattctcggt agcttaagtg atcattttgg
     2341 gcgtcatccg atccttatta tcagtttatt aggatcaagt atcggatatt tgctttttgg
     2401 tttaggaaat tcgatatgga tgttgttcct tggtcgtatc attgaaggat tgacggcagg
     2461 agaaatctcc accttatatg cttactttgc cgacatcacg gaacctaatg aaagaaccaa
     2521 agtttttgga tggatgggtg ctttagtcgg tataggaaca acgctgggtc ctattatagg
     2581 gggtctatta gctgagttgg ggaattctgt tcctatattt attggagcac tctttacttt
     2641 cttaaatgcc gtttatggct acacatttat gctagaaagc cttccaataa aaaaacgttc
     2701 agtagattta agtttctccc atgtaagacc ttttcaccaa ttacaacaat tattcaagat
     2761 ttcatccgtt attcctttat tgacagcagg ttttgctgtt tggttggcag ctggctctct
     2821 tcaatctatc ttttctcaat tttcgattga cgcctttcag tggaaggctg ggttggttgg
     2881 tttaagcttc tctttgattg gaatcttgga tactgtctcg caattgttca ttatgcctcg
     2941 attgctcaaa aaattttcag aacagcagat cacaagaata gggatgttca gtgaaatcct
     3001 cgcctatcta ttcatcacat tatctggaat tcttctactg ccgattttgt ttttatttgg
     3061 gattatctgt tatggtttcg gtgattctat ttttactcct gtattcaatg gccaactatc
     3121 caattctgtc tcagataacc agcaaggtct tgtaatgggc ggtacccaaa gtatacaatc
     3181 tctatcgcgc gtcatcggcc cgctaatcgc aggacagctt tatgctgcag caccatttct
     3241 tccgacggta ttcggatttt tgcttatgat ttttgcctat tatcactaca ataaaaaata
     3301 gtagcttcat ttgctacttc gtataaattc tctgtatcga ccgataaaac gaaatactgt
     3361 gtcaaattct tcttttgaca tattttcaaa tacagtagca tctcgctgta cccatttttg
     3421 atggagttgc tcgtgtctat tccttatttt ttgtccgatt ggcgtcaatt gaaaatagat
     3481 ttctttttta ttctcttcgc tttgataagt gtttatgatc cctctagcta tcagtttttt
     3541 tgttagctta ctgatggctc ctctagtcat gtaactagca ttcgctaatt ttgtcacgtt
     3601 aggatcaggg attttcccga tatgttcaat cacttctagt tcatttagag taaatcctgc
     3661 aaattctttt tccatttctg gtttattacg atgaataatc tcattagcta aatccagata
     3721 ttcttctatt agcagttgtc ttttatccat ttctacacct tctttttctt tcattatatt
     3781 gtttttttgt ttcctattca acaaagataa aaatattttg taggaaaacc caatctgaaa
     3841 ccaagaaa
//
LOCUS       DADVXE010000139         3778 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.145, whole genome shotgun sequence.
ACCESSION   DADVXE010000139 DADVXE010000000
VERSION     DADVXE010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.145"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..115)
                     /locus_tag="KB913_002857"
     CDS             complement(<1..115)
                     /locus_tag="KB913_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBB6821136.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="KB913_002858"
     CDS             246..698
                     /locus_tag="KB913_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821137.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="KB913_002859"
     CDS             712..1401
                     /locus_tag="KB913_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821138.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..>3778
                     /locus_tag="KB913_002860"
     CDS             1526..>3778
                     /locus_tag="KB913_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBB6821139.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTD"
BASE COUNT         1276 a          510 c          776 g         1216 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagat
//
LOCUS       DADVXE010000140         3738 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.146, whole genome shotgun sequence.
ACCESSION   DADVXE010000140 DADVXE010000000
VERSION     DADVXE010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.146"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            72..155
                     /locus_tag="KB913_002861"
     CDS             72..155
                     /locus_tag="KB913_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBB6821140.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            280..1017
                     /gene="erm(B)"
                     /locus_tag="KB913_002862"
     CDS             280..1017
                     /gene="erm(B)"
                     /locus_tag="KB913_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBB6821141.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1280..2143)
                     /locus_tag="KB913_002863"
     CDS             complement(1280..2143)
                     /locus_tag="KB913_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6821142.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2145..2417)
                     /locus_tag="KB913_002864"
     CDS             complement(2145..2417)
                     /locus_tag="KB913_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBB6821143.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2434..2643)
                     /locus_tag="KB913_002865"
     CDS             complement(2434..2643)
                     /locus_tag="KB913_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBB6821144.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(2742..3638)
                     /locus_tag="KB913_002866"
     CDS             complement(2742..3638)
                     /locus_tag="KB913_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6821145.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
BASE COUNT         1148 a          654 c          579 g         1357 t
ORIGIN      
        1 aaattttgta taataggaat tgaagttaaa ttagatgcta aaaatttgta attaagaagg
       61 agggattcgt catgttggta ttccaaatgc gtaatgtaga taaaacatct accgttttga
      121 aacagactaa aaacagtgat tacgcagata aataaatacg ttagattaat tcctaccagt
      181 gactaatctt atgacttttt aaacagataa ctaaaattac aaacaaatcg tttaacttct
      241 gtatttattt atagatgtaa tcacttcagg agtgattaca tgaacaaaaa tataaaatat
      301 tctcaaaact ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta
      361 aaagaaaccg ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg
      421 gctaaaataa gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg
      481 tcagaaaaat taaaactgaa cactcgtgtc actttaattc accaagatat tctacagttt
      541 caattcccta acaaacagag gtataaaatt gttgggaata ttccttacca tttaagcaca
      601 caaattatta aaaaagtggt ttttgaaagc catgcgtctg acatctatct gattgttgaa
      661 gaaggattct acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact
      721 caagtctcga ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaaa
      781 gtaaacagtg tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg
      841 aagctatata cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact
      901 aaaaatcagt ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccgttact
      961 tatgagcaag tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc
     1021 tatgagtcgc ttttgtaaat ttggaaagtt acacgttact aaagggaatg tagataaatt
     1081 attaggtata gggcacctct aataactacc aattaattca cctcaaaatg aaattagaaa
     1141 aaaacagcga aatttttaaa tctatttctt atcgatacaa attcctcgta ggcgctcggg
     1201 accccaacat gaggaaatgt ttttataaaa aaagagtagt taccgttttt tggtaactac
     1261 tcttttcctt ttttaaggtt taaatacctg gaagtttagg tgttttgggt attggtggtg
     1321 taggtagctg caagctttcc attttttgtt gaattgcttt aaattcaggg gtttcttggt
     1381 gttgattttg aaccattttt tgctctattc tctccaaagt cggttgaatt tctttccctg
     1441 atactttacg atttaattct ctttctaagg tctctttcgg actaatggaa ggcgtttcta
     1501 agcttgaata gagtttcact ccttctctat tgtaaagcct tatatcgcta aataagcccg
     1561 ttttatgaag ggtttctaaa ttggtcggta agtttttgac aacaatatca tgcgcttgtt
     1621 ttggtgttgc cctagctgtc attggatcat ctgcatacat ggtttcatat cgttcaatcg
     1681 ttcctaagta tgattcaatt ttcggtactg ccatgacgta tatttttgtt tcataacctt
     1741 tagattgaag cattgtggct gtttgaatgg gaacgtctgt tgttcgtcct gttccttcaa
     1801 tcactaaatt atagccttga tcgcttaaac ggctaataag tgcttctgtc atgcgattcg
     1861 aataaggggt aacgtgtttt actacgtctt tttcatagag tttcactaat tcgtcaaaat
     1921 ttgggtgctg ttgtttaaag gtatcattat caatgacaat aacattccct tgtgtttctt
     1981 caaaaattgc tgatcgcaaa ctggttttcc ctgaccctgg ttgcccacca agtaaaaaag
     2041 cggttggcga ttcaaccgct agtctatttt tagttagtcg ttcaacattc ttttctaaac
     2101 gatcttcaaa ttgcttttcg gtgaagtcag taatattcgc catgttaagc cactttctct
     2161 ttattcaaaa tttgttttga atattgattc attgaccgcc aatactcatg aatagcttgt
     2221 aattcttcaa atggttgttg aaataaatca acttcttgtg ccacttctaa ttgatttaaa
     2281 agattcactt ctagtaaacg agtattttta gtatctagtt catgattcaa aacataattt
     2341 aatacccgat tataaacact tgccgataac tcattaatga tttcaatttc aaatgttttt
     2401 tcatacgtaa ctgccatttc attttcactc cttttaaagt ttgtcaggta aatatttccg
     2461 tatatattct tctaaggctt gatccataac ttcttttacg tttccgccat tctttgctgt
     2521 ttcgattttt atgatatggt gcaagtcggc acgaacacga accgtcttat cccccattat
     2581 atcttttttt gcgctgattg gcgtatcatt tcgttttgct ttctgtgcgc ctaaatttcc
     2641 cacgatcgct cacttctttc tatttcttct tactatttat tttatcatca cctatcacaa
     2701 atcacaagtg atttgtgatt aatcacttgt gatttgtgat tctattcttt ttcattttct
     2761 aattgaatga ttcgctcaat catttcaaaa aatacgttct catacataga caaaactttt
     2821 ttgtcatagc ctttgtgttc tgtaatgcca tttttagacc aagtacttac tttattactt
     2881 cgcttgataa tatttcggaa aaccaaatta tcctctttat gttctttgta cagttcttcc
     2941 aggtttgatt ttatcgttgc gctgtccgta tcaactaaat aaggaacaaa accaatcata
     3001 tctagtccag ggttaaactg ttcttgcaaa tcaatcaaat aggaaatata gttttgaatg
     3061 ttgtttgtac tttcttcttc tgcttgtaaa gggatcataa cgtaatcact cgccacgatt
     3121 gcattatttg tataaacgct tggcgttggt acagtatcaa taataataag atcatagtca
     3181 ctttttaaag gtgctaaaag agtagcaagc aatctacttt cattttcaaa cgtccatgag
     3241 cgagttaatt ttggcagtaa catcaaatca aacgtgccag ggatcaagtc taaattatca
     3301 gtcaaatgaa taatagaaga agccaagttt ccatttttca agccttcata aaaattgaca
     3361 cgtggcaatt ctacctcaaa agtttttgct aagtcttttg tcaatgttgc ctgtaagtcc
     3421 ttatcgatca ttaaaacttt taaattcaat ttgtctgtca agtaagcaaa catagtcgat
     3481 aatttggact ttccaacacc acctttaaag taattattca agataataat tgcttcattt
     3541 ttattgttta aaatacgtct taattcttca agtattttta gtttttcctt ctccataact
     3601 acgccccatt ctttttttgt atagtaatat tgtatcatta agaatcacaa atcacaagtg
     3661 atttgtgatt aatcacttgt gatttgtgat aagtgatttg tgattaatat ataaaagccc
     3721 tctttaaagg gcttttat
//
LOCUS       DADVXE010000141         3549 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.147, whole genome shotgun sequence.
ACCESSION   DADVXE010000141 DADVXE010000000
VERSION     DADVXE010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.147"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            29..1420
                     /locus_tag="KB913_002867"
     CDS             29..1420
                     /locus_tag="KB913_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBB6821146.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            1436..2476
                     /locus_tag="KB913_002868"
     CDS             1436..2476
                     /locus_tag="KB913_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6821147.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            2495..>3549
                     /locus_tag="KB913_002869"
     CDS             2495..>3549
                     /locus_tag="KB913_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBB6821148.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTE"
BASE COUNT         1263 a          520 c          664 g         1102 t
ORIGIN      
        1 atattatttt gtgattagga gtgtatatat gaataaaaat ggagaatgga gtgctgcacg
       61 acggatattc attatattaa tggatgttat tgtatacaat gcagcaatat atagtagttt
      121 cttactgaag tttcgtggag agatcccatt acgaaattta gaaactttcc aacactcagc
      181 aattattatt tcagtgattt ttattgcgtt gaacattttg ttgggtgcat atgtttttta
      241 taatcgaatg atcagtgaca tcgtgtttgt cacagtcatc ggtcaggtat tgatgacact
      301 agggatcatg gtagtgactt ttgcgggccg ctggtttgct tttccacgtc ttgttatctt
      361 actttcattt gttctcggta cgcttttctt aagtatctat cgtattctcg tatataaact
      421 ttatttacgc gtaagtcgag ataaaaaggt cgtcattatt gggttagaaa aggatgtcgc
      481 accagcaatc caaaattttg gttcaaagaa aaacaacaaa cataaagtcg aagcagtcat
      541 tcttgataac tattatgcaa acatcaaaaa tatgattaaa gacatcgata ttgtctatct
      601 tgcttctcat atcgaagaaa ctgaaaaaat caaaatctat caattagtta ctaaaaatga
      661 aaaaaaattg tttttgaata caacatttga aaacttgaca ttgatcaatc caaatattat
      721 gaatttcgaa gatgaaagta ttattgaagc atctggattt agaatccaac ctgaatatga
      781 actattcaaa cgtttgtttg atatcatcgt ttcacttgtt ttattagtta ttgcttcacc
      841 atttatgtta ttcacagcaa ttttagtcaa agtgacatca ccgggaccaa tcatctataa
      901 acaagtgcgg atcacaaaaa atcaaaagga attttcaatc tataaattcc gctcgatgac
      961 cgccacagcc gaagcaaaat ctggaccagt tttagctaag agcaatgatg cacgagtaac
     1021 gcctgtaggt aaatttattc gagctgtccg ctttgatgaa ttaccacaaa tcttcaatgt
     1081 gctgaaaggc gatatgtcga tcgtaggacc acgtcctgaa cgtcctttct tcgtcgatca
     1141 gttcaatgca gaaaaccctt attactactt acggcataat gttcgtgctg gtatcactgg
     1201 gtatgcacaa gtctatggaa aatatgtctc tgattacaac agtaaattac gttttgattt
     1261 actttatatc aaaaaatatt cattgatgct tgatttaaag atcttgctgc aaaccatcaa
     1321 gatcctattt gataaaatgt cctctcaagg acttgaagaa gacgaaaatg tgatctcatt
     1381 ggcagaaatt gcttttccga atgaaaaaat ctttcgctag ttgggaggcg taaaaatgaa
     1441 caatccgaaa ttcagcataa tcgtaccagt atacaatgca gaagcaacta ttggtcgaac
     1501 gattgatatt ctaaaagaat tggattatga agagtacgaa gtcgttttag taaatgatgg
     1561 atcaacagat caaacacagg aaatcattca agaactgatt gaaaatgatg aacgttttga
     1621 attgattact acgaccaatc aagggcccgg attagcaaga aacgaaggaa taagacagtc
     1681 aaaaggagaa tatctcttat tcttcgatgc agatgacacg ccagtaaaaa cgatcttgtc
     1741 agattatgat catttgctag aaaagagtcc aaaagcggat cttgttgtta gttcgtttgt
     1801 ttttcgtaca atggacgagg gaagaatcgt ttccgaaaaa gaaaacttag ttacagaatg
     1861 tcactatcta actcacgaag agtttataaa agacatgtat cagttaatga atgaacagtt
     1921 gatgtatgtt gtatggaaca aatgctatcg tagcgatatt ctgaaaaata accaaattct
     1981 atttaaaact tataatagtt gtgaggatcg aatatttaac ttacattatt atgaatactg
     2041 tcatcaagtg atcatgaacc caaaagtaga atatatttat gaatttgaag gtgggaaggg
     2101 gatcactaat caataccgac ctaacaagtt cgaaacattt aaagaattct attcattagc
     2161 aaatactgta acagacgata ttaataaaga cggtatggcg gcgcttcttt taaaagggac
     2221 aacttcagtt attttttcta tttatagtac ctctgcaaga acttcaaaag agaagaaaga
     2281 cgaagcaaag cagatattga gtgatccagt gatccgagaa gccaagcaaa ttgctaagac
     2341 ggattcttca gcaaaaaaaa taacaaagtt gctttacaat atgccagctc cactattttt
     2401 atctgctgta aaagttggaa gcttcgttga agtgaaaatg ccagggttaa tggctgcttt
     2461 gaagcgagta tattagttaa tggaggaaaa tataatgaaa agaattttgc attttcaggg
     2521 acgaatgggt ttaggtggag cagagtcttt catgatgaat ttatatcgta aaattgatcg
     2581 tacaaactat caatttgatt ttttgattta tgaagattat gcagatgttc aagactatca
     2641 ttcagagatt gaaagattag gaggccgtat ttttgttgta cctaatccta agaaaaatat
     2701 ttttaaatat ttaatagaag tgaataagtt actaaaaaaa gaatcttttt ctatagttca
     2761 caatcaggtt tattttggcg ggggaattaa tttatggtta gccaaaaaga atggaatcag
     2821 acagagaatt gctcatagcc atgcaactga agatggaaaa tctcaaaata ttgtaatgaa
     2881 tgtattgcgt aaatttttaa ccaaattgtt gttacaaaat gcaacagact accttgccgt
     2941 tagtcaagaa gctggtgaaa gtctgtttca aaaccacccc tttgagatag ttcataatgg
     3001 tattgattta gagctttata gtaaaaattc agaagctaag gttaataaga gaaaagaatt
     3061 ggatatctca atgagtactt ttgttgtggg aaacattgga cgattagaga aacaaaaaaa
     3121 tcaatcttat ttgttagaga tttttttaga aatactaaaa atgaattctg attcttactt
     3181 gattttagta ggtgaagggt cacttagaaa taaactgaaa gccaaagcag tagaattgga
     3241 tatagagaaa agagtaaaat ttttaggaga aagaaacgat attcccgagt tattatctgt
     3301 gatggatgtt tttgtaatgc cttctcttta tgaaggtctg ccaatggttg gattagaagc
     3361 acaagcagca aaattaaaat tagtcttagc agatactatt tccaaagata caaagttaac
     3421 aaataatgtg gattttgtat cattagatga aacaccacaa gaatgggcaa aaaaagtaat
     3481 aaaagagccg tatgctaata aaataacaca agaactaaag agttatgatg tttcgtacac
     3541 tactgaaca
//
LOCUS       DADVXE010000142         3495 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.148, whole genome shotgun sequence.
ACCESSION   DADVXE010000142 DADVXE010000000
VERSION     DADVXE010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.148"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..635
                     /locus_tag="KB913_002870"
     CDS             <1..635
                     /locus_tag="KB913_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBB6821149.1"
                     /translation="MINTWNNIKDSFWNIVTGIVNSAENAWTNLKNGVSNAINRVKEI
                     FNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTIKGIAGNIKNWIKGALDIHSPSRW
                     MRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTPSVQPVVNGISHLPITQTKQNISA
                     SETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQMKRDAGAVGGTLYAT"
     gene            625..1365
                     /locus_tag="KB913_002871"
     CDS             625..1365
                     /locus_tag="KB913_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6821150.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            1362..>3495
                     /locus_tag="KB913_002872"
     CDS             1362..>3495
                     /locus_tag="KB913_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6821151.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWM"
BASE COUNT         1293 a          433 c          688 g         1081 t
ORIGIN      
        1 ccatgattaa tacatggaat aacattaagg actctttctg gaatattgtt actggaattg
       61 ttaattctgc tgaaaatgca tggacaaatc taaaaaatgg tgtttcaaat gctattaatc
      121 gggtaaaaga aatctttaat tcgttaaggg aagtcaattt atttgaaatt ggcaagaaca
      181 tcattgatgg acttataaat ggtgtaaaag aaaagtggaa tgctttgaaa gatactatca
      241 aaggtattgc aggtaatatc aaaaattgga ttaaaggagc tttagatatt cattctccat
      301 caagatggat gcgtgatatg gttggtaaaa atattgttca aggtattatc gttggtattg
      361 ataaagagca aagtaagtta gatcaaacca tgacaaattt agtaaaaaca ccgtctgttc
      421 aacctgtagt aaatggaata agtcacctac caattacaca aacaaagcaa aatatatctg
      481 ctagtgaaac aaaagaaatt catttacatt taaatgttta tggagattta cctgattcaa
      541 tggttcgaaa gattactaca aaaattaaaa cagaattgac aagacaaatg aaacgagatg
      601 ctggtgcagt aggaggaaca ttatatgcaa cttaagagag gacaattttt tattaatcaa
      661 cattattctt ctgaatttaa tgtgtatatt caaaacaggc ctgcttctgt ttcagctagt
      721 cgagtaattg aattgagaga gcgagaagga aatgattcta tcattattga taaaggctat
      781 tacaaaaatg tgactagaaa gattgagtgt tactataaag caccttcaat tgatatggtg
      841 caggagtggg aagatcgaat cactgaatgg ttagatatgt cgtcttatag tgattttatt
      901 ctttactatg atgaacaata tatttatcaa gctgtagtaa tagaaggacc tgaatttaaa
      961 ggaacaagaa aaacaggaaa tattgtccct tttgaattta cagtgagtat tcgaccattt
     1021 aaggaaaatt acaatggtag atttactatt cgacaaacag aaacttttga aatttataac
     1081 ccagagaagt attcttcaaa accgcttatt aaattgagtg gttctggaga tgcttctttt
     1141 tatattaata aggataaata tgatttgaaa tcgttggaca gagaattatt tatagattct
     1201 aaattagaag aggcttatcg aaaattagat ggtaatttag aacatcagga tcaggtcacc
     1261 ttatttttag attttccatt tttatatcct ggaaaaaatg aaattaaatg gacgaaaaat
     1321 attcattcat ttgaaataat gcctaggtgg tggagaaaag tatgaaacca agaatatata
     1381 gtcctactga aacagatttc tcaacgaatg gcttaggaat tttaaaggat tgtacaagat
     1441 gtgaaatata tgaagtagct aatggaaaat atgaattaga gttggattat cctttaggaa
     1501 ctagatttga tgaatatttt gaaaatgact atcaaataaa agcaaagcca aacgatcaag
     1561 aagagtatca tatctttttt attgatgata aagatataga tactttttta aatacagtaa
     1621 ctatttatgc tcagagtcgt acaaatcgac ttggaagacg ggtagtcact cttgtggaag
     1681 tggactctaa aactggtcaa gaagcgatat caattattga aactaaaatg gataaaaaat
     1741 ctgacatacg actttattct gatattacgg ctgtttctag cacaatcttt gaagcgagaa
     1801 atgttttaaa ttgtattgct ggtgaacaag gatcattgct tcaatattgg ggcggagaaa
     1861 ttaaacgtga accatttaag ctttctttgt taaagcgaag aggtcgcaat aatgttggaa
     1921 cgattcggta tggaaaagat atgtctggtt tgaaggtcaa attagattgg acaggtataa
     1981 aaacaagaat tattccatat gctgatcctc aaagtgaagt aggtacgact aatcgaattt
     2041 atggttcgcc agtagatagt gcctatatta ataactatcc tgatgtctat acagaacatg
     2101 ttcagtttac agaagaacaa ggagtaaaag acattaagag cttaaataaa atagctaaaa
     2161 attactttaa aacgatcaat cctggctgtg ataagcctaa agtttctatt acggttgaat
     2221 ttgataagtt gactgatagt gaagaagcga aagaatttgc gaagattaga aattatggtc
     2281 tgtttgatac atttaaaata tatcataaaa aatataatat ttatcttgaa tcaaaggtta
     2341 gtggactaca atacgattct ttatctgaaa aaactttgaa attagaagca ggagacattc
     2401 aagttgcttt ttatcagcaa caagctgtaa ctattcagga taaattaaaa gattatgcaa
     2461 cgaataatta tatgagtgat tttaatgatt atgtttcttc aatgattaca ggtcaaggca
     2521 gtgcaggagg atatgtagtt ttatggccaa aagaaaaacc ttccaacatc tttattatgg
     2581 ataatccaga tttagaaaag gcaagagaag tactaagaat gaataaaaat gggattgctt
     2641 tttctaagaa aggatggcgg gggcctttta attcagcttg gacattagat agtatattta
     2701 atgccaattt tatacaaact ggattaatca aagcagatat ctttcaaaat tcttttaaca
     2761 agactggaga tgtattgaaa ttagttaatg gactactcca aatttggaac aacaaaaaga
     2821 aaataatgga gttaactaaa aaaggaatgg aattttggaa ttctaagggt tcaattggaa
     2881 cgattggaac aactgattct gttggtaatc cttttcctgg ggcttctact ccaaccccta
     2941 ttgaagataa ttctttagtt attcgtacaa atggagacgg caaatatatt ttgatttctc
     3001 ctaaagtagg aaaaggatta gttttattag gaaatggtaa agcaatttat tttggagact
     3061 tagatgtaca aggaaaactt acagttaaag gaaaagaaat aattcctgga caaggtggtg
     3121 gtccatcggg aggtggagaa tctactggtg ggtatcctag tgaattaaaa acagatgcag
     3181 aaaagagagc ttggagaatt tacgatattt tgtgtaataa cggatttacg aaacaatctg
     3241 catgtggaat attggggaac attcaacaag aaacaggagg aacttttgat cctgatactg
     3301 ttcaaatagg tggaccagca tacggattag ttcagtggga tggttcttca tatcctcttg
     3361 ttggtccagc aacatgggat ggaaaagttt atgttcaaaa cttatttaat gctgcaggta
     3421 ttaaagaacc aataacgagc ttagatgcac aagttcgatt gcttatttgg acatttacaa
     3481 atggacaatg gatgg
//
LOCUS       DADVXE010000143         3301 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.149, whole genome shotgun sequence.
ACCESSION   DADVXE010000143 DADVXE010000000
VERSION     DADVXE010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.149"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(52..2523)
                     /locus_tag="KB913_002873"
     CDS             complement(52..2523)
                     /locus_tag="KB913_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6821152.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            2796..>3301
                     /locus_tag="KB913_002874"
     CDS             2796..>3301
                     /locus_tag="KB913_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6821153.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSM"
BASE COUNT          976 a          664 c          595 g         1066 t
ORIGIN      
        1 aaagatacac gagtggttgt tcttttttac tcttttttga gatacttttc gtcaattttc
       61 tcgtttaaat atcgatagaa attttttagc tacgcgacta aacggctttt gctctttttc
      121 atttttacgt tcaaacaaat attctaccaa tgtggtcaaa tgcctaaaaa tcgaatctgc
      181 cgagaaaaat agaatgctca acagcaaaag tgatacagct gagataccgg tgattgaaaa
      241 cagcttatgc aaaaagatga ccgaaaaaaa gttaccgcta gcacagaaaa gaatgatctg
      301 acttctgaat ttattcagcg gtgaacagat tttatagaga acgaggaacc ctactgcaat
      361 caaaagcatg gtagatgctg tagaaacatc tgttttattt agattcaaag tcaccccgca
      421 gatcaccaac gcaccgacta cgatcatatc tgttagtcca cctggcacag ctttttccat
      481 cacattcatg atgaatttcc ctctgattcg ctttttgttt tcttctagag caagcaagaa
      541 agatggaagt ccgatagtaa acaaactaat caatgtgatt tgtgatggtt ctaaaggata
      601 ggtcagagca aagatcactg aaaacagtga gagcaaaaag gagaaaatat tcttcactaa
      661 aaacaagctg gctgatcgct caatattgtt cacaacgcgc cgtccttctg caacaacttc
      721 tggcatgcgt gaaaagtcag aatcaagtaa gaccacttgt gaggcctgca tggcggcttc
      781 atttccggaa gccatcgcta tactgcagtc tgcttctttc atggctagaa tatcattcac
      841 gccatcacct gtcatagcta ctgtattgtt acgctttatc aattgaacga agattttctt
      901 ttgttctggc ttgacgcgtc caaaaactgt atatttttcg acagctgctt catattcttc
      961 ttctgataat ttagatgcat caacgtactg atcagcatgt gaaatccctg cttggacagc
     1021 tacattggat acggtgagcg gattatctcc agaaatcact ttgatggcta cttgctgttt
     1081 tttgaagtaa tcaaatgtgg ctcttgcttc ttttctgata ggattagcaa tcagaatata
     1141 gcctaatggt gtgactgctt ctgtcaatac tggttcttca agaatcccat cgtacacacc
     1201 aaagaccaac acgcgatagc ctttttcagc gaaagaaaca aactcttccg catattccgg
     1261 caattgatcg cgcaaaacca tttcgggcgc tcctaaaaca tacaccttgt ctgccaacgc
     1321 tacactgctg aatttttgga cagaagaaaa aggaataaca tggtgatagg attgatcagt
     1381 ggtttttgta aaatatgctt taacagcttc cattgttgca ttgtctcctg ccatcgcttt
     1441 tgcatagtca gcaatgcatg cttccaattg atctgactga ctgattattt cttgtttttt
     1501 agagacgatc attttttgaa cagacatttt attttctgtg atcgttcctg ttttatctac
     1561 acaaaggaca tttacccttg ccaatgtctc aatgcttttc atattgtgta aaagaactct
     1621 ttgctttgct agtttagtcg cacttaatgc taatgcaatc gtcgtcagca agtacagtcc
     1681 ttcaggtatc ataccgatca atgctgcttc cattgcaacg acactttctt tgatcgtgtt
     1741 tccattaaaa aagtaacttt gagaaaaaag caggataccg ataggaataa tgatgatccc
     1801 aatccatttg atcaattgat taagagaagc aatcatctcc gactgttctc cttctcccat
     1861 tgtcttggct ttgactgtca gctgggaaat atacgaatct gctccaactt tgtctaatcg
     1921 ggcgtaagct tttccggaaa caatgaaact gccggacatt aatggatcac ctatttcttt
     1981 ggttatttca tctgcttcgc ctgtcaataa agcctcatta acttgcagtt tcccttccac
     2041 gacctctgca tctgctggaa tttgatatcc agtctctaaa ataacaatgt catctattac
     2101 aaggtcttct atatctattg tttgttctat cccgtctcgt atgacattga cttttgctgt
     2161 atttaaaaca tttagttcgt ccaagatctt tttggatcga atttcctgaa aaatggcgat
     2221 tcctgtattg gctatgataa ctggtaaaaa agtcaagttc ttataggatt ctactaaaca
     2281 aagcaaaatg gctaagataa gaaagatcaa attgaaatac gtaaatatgt tttccaatac
     2341 gatttgctga tttgttttga atgtgggatc gactgaatta tttgctgcac ctttttctat
     2401 tcgttccttg acttgatctg ccgttaatcc ttctttatac gatggaaaaa gacggatgac
     2461 tttatctgat gatctttgtg ttactttctt ttttttactt cgatttatcc atttattctt
     2521 catgtggcta cctcgattga tttcgttttc tggatatttc caaacttctc ctatccagta
     2581 tagaacagat atggaaagtg ttcctcacat taagcttgca aacacctttc attcctgtca
     2641 tatagcaaaa aaaaagggtt ctataatatt ttgtgttggt ggaaaatcga aggcgatttt
     2701 ctactaacac tttttcttcg tttcaactca aaaagagact cacttttggt aaaatttagt
     2761 cgaccaaaac gtcatcctac caaaggagtc tctcaatgga taatcatact agaaaattac
     2821 tcggattaac agataaacat ttattttttg atgaagaatg gctgattgaa aaagaatata
     2881 aaggcgttca agcgcagttt attaaaggaa aattggatga ctcttcttcc tattgtgaac
     2941 actgtcgatc ggttcgtatt atccgcaacg gttcctatac gacacgcact cagatgttga
     3001 aagtcaaaga aaagttaact attttagaat taaaacgtac ccgttttctc tgccatgatt
     3061 gtggaaggac cttttctgcg aaaacggact tagttgatga acatcatcaa ctaacaaagg
     3121 aactgaagca ggtgattctc atggaactgt acgaaaatca atcacgtaaa ctaatcgcta
     3181 agaagtactt cgtctcggat gggacggtga cacggatctt gcgtgaagca acgaagcatt
     3241 accagccacg tatgaacttc cttccgacgg tgttgtgtat ggatgagttc aaatcaatga
     3301 a
//
LOCUS       DADVXE010000144         2898 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.150, whole genome shotgun sequence.
ACCESSION   DADVXE010000144 DADVXE010000000
VERSION     DADVXE010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2898
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.150"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            48..2489
                     /locus_tag="KB913_002875"
     CDS             48..2489
                     /locus_tag="KB913_002875"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBB6821154.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(2646..>2898)
                     /locus_tag="KB913_002876"
     CDS             complement(2646..>2898)
                     /locus_tag="KB913_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6821155.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVPHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT          939 a          519 c          683 g          757 t
ORIGIN      
        1 ttgtttttac agcaaagaat ggtatatttt tgtaggaggt ggcttacttg aaagaagtcg
       61 ttatgataga tgctgcaaga acgccgatag gaaagtatcg cggaagttta agtccattta
      121 ctgcagttga attaggcaca cttgtgacta aaggattatt agataaaaca aaactgaaaa
      181 aagataaaat cgatcaagta atatttggaa atgtcctgca agctggtaat ggtcaaaatg
      241 ttgccagaca gattgctttg aacagcggtc tccctgtaga tgtcccagca atgacgatca
      301 atgaagtttg cggatctggt atgaaagcag tgatcttagc acgccagctg atccaattag
      361 gtgaagcaga acttgtgata gccggcggaa cagagagtat gtctcaagca cctatgctga
      421 aacagtatca gtcagaaaca aatgaatatg gtgaaccaat ttccagtatg gtcaacgacg
      481 gattgactga cgcattttca aatgcacata tgggattaac cgcagagaat gttgcaacac
      541 aattttctgt gagcagagaa gagcaggatc gctatgcctt gtcgtcccag ttgaaagcag
      601 cacatgctgt cgaagccggt gtattttctg aggagatcat cccagtcaag atttctgatg
      661 aagacgtgtt atctgaggat gaagcagttc gtggaaatag tacattggaa aaactgggca
      721 cgttacgtac agtattctca gaagaaggaa ctgtaacagc aggaaatgct tccccgttga
      781 atgacggtgc ctctgtggtg atccttgcat ccaaagaata cgcagaaaat aataatctgc
      841 cttatttagc aaccatcaaa gaagtagcgg aggtcggtat tgacccaagt atcatgggaa
      901 tcgctccaat caaagccatt caaaaattga cagatagatc aggaatgaat ttatcaacaa
      961 tcgatctttt tgagatcaat gaagcatttg cagcttcttc tatcgtagtt agccaagaac
     1021 tgcagttaga tgaagaaaag gtcaatatat atggaggagc aatcgcatta ggccatccaa
     1081 ttggtgcaag cggtgcacgt atcttgacta cattagctta cggattgctt cgtgaacaga
     1141 agagatacgg tattgcttca ttatgtattg gtggaggttt aggcttggca gtcttgttag
     1201 aagcgaatat ggagcaaaca cataaggatg tgcaaaaaaa aaagttttat cagcttacgc
     1261 catctgaacg gcgcagtcaa ttaatagaaa aaaatgtatt gacacaagaa actgcgttga
     1321 tttttcagga acaaacactt tctgaagagc tctccgatca catgatcgaa aaccaagtga
     1381 gtgaagtgga aatcccaatg gggatcgcgc agaattttca aatcaatggc aagaaaaaat
     1441 ggattccgat ggcaacagag gaaccatctg tcattgcagc tgcaagtaat ggtgcaaaaa
     1501 tctgtggaaa tatctgcgca gaaacacctc agcggctgat gcgagggcaa atcgttctat
     1561 caggaaaatc ggagtatcaa gcagtgatca atgcagttaa tcatcgaaaa gaagagctga
     1621 ttctttgtgc aaatgaaagt tatccttcaa tcgtgaaacg cgggggcggt gttcaagata
     1681 tctctactcg ggaattcatg gggagtttcc atgcatactt atctattgat tttttagtgg
     1741 atgtaaaaga tgcaatgggc gctaacatga tcaactcgat tcttgagagt gtggcaaaca
     1801 agttacggga gtggttccct gaagaagaga ttctattcag tattttaagt aattttgcta
     1861 cagaatcatt ggcttctgcc tgttgtgaaa tcccattcga acgcttaggg agaaacaaag
     1921 aaatcggtga acaaattgcc aaaaaaatcc aacaggcagg ggaatatgcg aagcttgacc
     1981 cttaccgtgc agcaacgcac aacaaaggga tcatgaatgg tatagaagct gtagtggcag
     2041 ctacaggaaa tgatacacgt gcggttagcg cttcgatcca cgcctacgcg gcaagaaatg
     2101 gattatacca aggattaaca gactggcaga tcaaagggga taaactagtt ggaaaactaa
     2161 cggtgccttt ggctgttgcc acagtaggcg gagcttccaa tatcctgcca aaagcaaaag
     2221 catctttagc tatgttagat attgattcag ccaaggaact agcacaagta attgctgcag
     2281 tagggttagc tcaaaacctg gctgctttgc gtgcattagt tacagaagga atccaaaaag
     2341 gccacatggg acttcaagct cgttcattag cgatctcaat tggggctatt ggtgaggaaa
     2401 tcgagcaagt tgcgaaaaaa ttacgtgaag cagaaaagat gaaccagcag acagctatac
     2461 aaatattgga aaaaatccgg gaaaaataaa aaagcaatat ctttagaaga ataaagcaag
     2521 atttacagtt attttattta ctgcagatct tgcttttttg gctcttcgtc aaattgtgtt
     2581 ggcgaagaca aatttgaata aaacttagtc cgatatgcgg cgcgttctgt gcgccgcata
     2641 tttttttagt tttcaaagat cagaccttgt tgtaaataga tccgtgcccg aaagttataa
     2701 aagttgcgat aaccaaacgc aattcgttta atcagcttga tcttgttatt cagcccctca
     2761 gtgacgccgt ttgagtgggg caccttaaag gcatttgaaa tacccgattg gtagcgatgg
     2821 aagatcgtga atttcttttt aaacgactga ggtaacgtag atgaaattgt tttaagggtt
     2881 tcttgaaagc cttccgta
//
LOCUS       DADVXE010000145         2770 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.152, whole genome shotgun sequence.
ACCESSION   DADVXE010000145 DADVXE010000000
VERSION     DADVXE010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.152"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(77..1876)
                     /locus_tag="KB913_002877"
     CDS             complement(77..1876)
                     /locus_tag="KB913_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBB6821156.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2000..2596)
                     /locus_tag="KB913_002878"
     CDS             complement(2000..2596)
                     /locus_tag="KB913_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6821157.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT          978 a          522 c          480 g          790 t
ORIGIN      
        1 aaaaaacgca tatacctgcg gtggcaggtt atgcgttttt tgttgtataa agactttttt
       61 cattaacgat ttttgattag ccgactccca aaacaaaatt tagcagttta tctgaataag
      121 tgatttcttc atctgtttgt ttcacacttt catttagtag tcccatctca tcggttatga
      181 taccatccac accataaaac atcatgcgac tcatagcatc tgaatcgttg attgtccata
      241 catatacttc ttttccgtct tggtgggcag aattaatgaa gttacggttg atcgtactat
      301 attccattgt cagaaaatca gcaggcgtca cagggggccc aacaatattg aaaggtaaga
      361 tgtagcccac ataaaagttt ggttctgctt cttttaaatc tgaaacggtt tggtacgtca
      421 aactttgcaa aatatgatgg ttctctaaga taactttgcg gtatttatgg acaaatcgtt
      481 cgacaaggtc atccgaatct tttttagagg tcttgatctc aataagtaat ttttggttta
      541 gcttatgtgc tttttccaaa taagaatcaa aagaacaaac aggggcttgc actccgtttt
      601 cagtaactgt aagatttgtc aattctttca atgtaagatc ctgtggtgtt ccatttaccc
      661 ctgttaagtg acgaagattt gcatcatgca tcactacgaa atgaccatct tttgtttcct
      721 gaacatccat ctctacataa tcaggatgat agtctctgct tgttttttca agtgcttcta
      781 aagtattttg cgccccattt tgggtactca cacctctgtg agagacagtc actggttttg
      841 tctgaacagc tgaagtcaga taatccatat tgtaaagaca gacgccaata ccgaaaaaaa
      901 ctgcaaaaag agtcaaacca gtgtttttca gcgcagagaa acgcaagttg ggggcttgtg
      961 ggataaacca cttagggatc tcaggcaaga agccttcgtc atccatgaaa tcaacaatga
     1021 tataaaaaat ccctacggta gacatcacga tattgaataa taaaatccct tgtaaaagcg
     1081 tcatagcaaa cacagcgctg atcaatgcat agtctgggaa aaattgttca accatacttt
     1141 gtgccaaaat aacaacgata tatcctaaag aagaaaggag taaaatcgta ccgccaatca
     1201 caataaattg gcccgtgatg gccaaaagac gcgatttggt caatgaccag ctttcccgaa
     1261 tggctgctcg aaaaggacga tctcgtagaa tcatttccgg taaagcaaaa atcagtcgaa
     1321 tcccaatata gccaaggaaa atataaacga gtaaaaagga actgacgatg atccaacgat
     1381 tagcaaaaat aaaatccata atgaaagcgg ggatttttat ttttgacagt agatcagaat
     1441 taaaacttaa tccgctgatc ggtagaatca ataaaaaata agcaaggaaa aacaaaaaag
     1501 taatgggtct cactttcttc agctgaagta tcgtcaagtg taagagttgc ttcaaagaga
     1561 ttggttcttt ctttttaata aaaaaaacac tcatcaaaag aaaagtaaat tcgaaataaa
     1621 ctaacagtaa aatcgtcatc aaaactacga ttaacgagag tagaacccca ggatgttgag
     1681 aaaaaattga aggaatattg tcataagaca aatagtcaat tgcccctcgg tgtaaaataa
     1741 aacgggtcgt actgctcaat aagggtaaac aaataaataa aataaagcca tgcatcagca
     1801 agacatcacg gaaataagct tgtgttcctt ttaaaaagtc ccaagcatta cctaagctac
     1861 gtttcaaata attcatccta tcacctgctc ttcacattgt agcgcaaatc taatgaaaaa
     1921 ggaaagggtg cagtgtgttt tgcagaccct ttcccagatt taacattgtc aatcaatgac
     1981 taattttaca aaataaatat tatccaagaa gaccacttag atattgacct ccataaatca
     2041 aggccatact atataagaaa atcgacagtg gtttagcaat caaaatgatt agtgtatatc
     2101 gtttcactga catgtttgtc aatccagcca tcaaacataa cgcatcgtca ggagcaactg
     2161 gaagaaaaat agctagagca aacagcttct caaaacggtt ttgattatcc agccagccaa
     2221 tatatttgtt atatgtctta tcgctaatca tggaaagtat gaatggcttt ccataacgac
     2281 gccctagcag aaaaatgata atcgaaccaa tgcagattcc aatatagtta tagataaatc
     2341 cagcataagg gccaaatatc aggacaccag ctgcagtact gatccctcca ggaatgattg
     2401 gaataactac ttgcaggatt tggatgaaga caaaaataat cggtcctaaa atgatggaat
     2461 cacctactaa tcctcttaac gcattcaaat ctttgaaaac acctaaatta ataaaataaa
     2521 tcgtcagcgc gattgatagg cctaatccga taatggatat gaaatttatc agttttcgag
     2581 aggcagcaat attcattatt catcaactcc ttagaggttc tttgttaact atactttact
     2641 agaaaagcaa ctaactgcgc cattttttga tatgacagaa aacaaacaat tttgtaagtt
     2701 catcataagt ataaaagatt gatctcaaaa aaacatccaa ctaaagactt atttaataac
     2761 ttgttttttt
//
LOCUS       DADVXE010000146         2699 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.153, whole genome shotgun sequence.
ACCESSION   DADVXE010000146 DADVXE010000000
VERSION     DADVXE010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.153"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            217..1617
                     /locus_tag="KB913_002879"
     CDS             217..1617
                     /locus_tag="KB913_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821158.1"
                     /translation="MWLLNICTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIY
                     YRSAIAEAIALTIIPAVLYYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIA
                     CMIIVRLFLSKQIKNDIKFVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTD
                     LQLEALSISDSIIQALNNDITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTW
                     VCVTNLFPWFLFQKTPISLLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGA
                     TVVFLLVTSIAAKENYAKVIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERP
                     HLEKHEVKVGESWEKGKYKAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVND
                     SYKKHGLVNVDVNAGENKIEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKD
                     SRYVTKKEINKKNENK"
     gene            1604..>2699
                     /locus_tag="KB913_002880"
     CDS             1604..>2699
                     /locus_tag="KB913_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821159.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYN"
BASE COUNT          897 a          404 c          451 g          947 t
ORIGIN      
        1 atgagaaatg ctcaagaaat ttatacaaca ggtgatttat cttttcatct ttcacgaatc
       61 aaagggttat cttctatttt tgaagggcca atcaactata caacatttaa caattatgga
      121 gatggactga actattttta tccttttctt acaataattc ctgcagtcgt tttttatgga
      181 atttcaaata acttaatatt aagttatgtt ctatatattt ggttattaaa tatttgtacg
      241 attctgatta gtttttatta tggagaaaag ttttttaaaa agatagatgc tgctttttta
      301 tttagttgtt tatatacttt tgcaacttat cgaacagttg atatctatta tcgatccgca
      361 attgcagaag caatcgctct tacgattatc ccagctgttt tatattatgc ttatggattg
      421 atattcaata gagaaaaaaa agtcatcgct ttatctgtca gtataagtct acttgtgtat
      481 actcatgtct taactacact attgtgtagt gcattgattg cttgtatgat tatagttcgt
      541 ttgtttttaa gcaagcaaat aaaaaacgat ataaaatttg tggtcgtgaa tttagtaaag
      601 gctgtttttt tgacttgtgc attaactagc tatttttggt atcctatgtt gcagcagatg
      661 aattatcaag aaatacacag tcccttcaaa acagatttgc agctagaagc actttctatt
      721 tcagatagta tcattcaagc gttaaataac gatattacaa catacactat ggggttatta
      781 ggattggttg cgttgatttt tcctttattc atactgaaag aaatggagaa aaaagaaaaa
      841 atcatctatg ttggcgtagt ttctacatgg gtatgcgtaa ctaatttatt tccatggttt
      901 ttgtttcaaa aaacaccgat aagcttactc cagtttcctt ggcgtatctt aggtatccaa
      961 atcttttttt cttcaatgat cataacgctt gtttttatga aaaagactat gaataaaaaa
     1021 tattcatggt taatcattgg cgctactgtg gtgtttctac tcgtcacgtc tatagcagca
     1081 aaagaaaatt acgcaaaagt tatccaatca aaacacggtc atattgttat caatgaagaa
     1141 acactcccac gttatacaac atcagatatg ggaggattat acgattacgc cccaacagaa
     1201 gcgataaaag aaaggcctca cttagaaaaa catgaagtaa aagtaggaga atcgtgggaa
     1261 aaagggaagt ataaagctgc agataataac attacttaca cagtggcaag caacaaaaag
     1321 caaaaagtga cagtaccagt atatgcttat ttaggtacac aggtaaaagt aaacggtaaa
     1381 gtcgtaaatg actcttataa aaaacatggc ttagtgaatg tggatgtaaa tgctggagaa
     1441 aataagatag aaattacaac aaaatatact ccaactgctc tcatggcttt atggatcagt
     1501 attctgactt attgtttagt ggtgtattca agttttaaac gatttgcacc taataagttg
     1561 aaagattctc gatatgtgac taaaaaggag ataaacaaga agaatgaaaa taaataaaaa
     1621 agtagtaata ttgagtggat taattatagt tagtagtata tattctttca tctttttcaa
     1681 aaatacacag agtatttata ccactggaga tctttctttt cacttatctc gaatcaaggg
     1741 gttatcgact atttttacca gtccgattaa ttatgagaca ttcaattata ctggatatgg
     1801 tgtaaattat ttttatccct ttctgacttt ttttccagct gtaatgttat attggatgac
     1861 aaaaaatttg attgtaagct atattattta cgtttggtta ttgaacttgt gtacaacact
     1921 cgtagcttat cattatggcg agcggttttt aaaacaaaaa aaagcggcat ttttatttag
     1981 ttgtctctat attttctctg cttatcggac agtagacatc tactatcgtt ccgcaattgc
     2041 cgaagctatc gcaataacac ttgttatccc tgtattattt tatgcttatc aaatcatctc
     2101 tggaaaagaa gaaaagtatc cgtctgtaaa gctagcattg agtatgagtt tgctagtgta
     2161 cagccatgta ctatcaacat taatgagtac agcattaatt atcattttta tttttattcg
     2221 tttggtttct aaaggtttca agaatgcaga ttttattgct atatttaaaa aattatttag
     2281 tgcggcagga atgacattgg ttctgacgag tgctttttgg tatccgatgt ttgaacaaat
     2341 gctctaccaa aaaatcaaca aacctagcgt gacaaattta tatgctcatg catctaatgt
     2401 gttcgatagt ctgactgaag ctatgaacaa cgacttaact acttactcaa tgggactagt
     2461 tggtctgtta tctttatgta ttcccctgat tttatttaaa aaattaacaa acatagaaaa
     2521 aaagatttat tatggtacgt gtttgacttg gctagctaca actagtttgg tgccatggta
     2581 tcttctgcaa aatacgccag ccaaattgtt acaatttcct tggcggatct taagcttgca
     2641 aataatattc tcttctctga tattaacgat gatatttttc aaaaatagaa gatacaata
//
LOCUS       DADVXE010000147         2695 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.154, whole genome shotgun sequence.
ACCESSION   DADVXE010000147 DADVXE010000000
VERSION     DADVXE010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.154"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            390..1421
                     /locus_tag="KB913_002881"
     CDS             390..1421
                     /locus_tag="KB913_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6821160.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            1530..1955
                     /locus_tag="KB913_002882"
                     /pseudo
     CDS             1530..1955
                     /locus_tag="KB913_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
     gene            2068..>2695
                     /locus_tag="KB913_002883"
     CDS             2068..>2695
                     /locus_tag="KB913_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HBB6821161.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIK
                     IIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLK
                     IHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          955 a          471 c          448 g          821 t
ORIGIN      
        1 agtaccaact atttctaata cttctttaag aattatccca acaatatcgt tagacaaacc
       61 attattgaat aaatggagag ccaatcgatt ctgaaaaaat gttttctaat ttttcggaaa
      121 taaaagaaag agcctcctgc cattagaacg aaccaaatcc atttcattgc tcatgaagta
      181 accacatagc taaaaagagg ataaatcaat taaaagatca aaagaatgac tgcactaata
      241 aaataactaa aaatgtatct tcttacttca tatcttttag ctagtactta gttaaaaatt
      301 tgcttcctaa gatcaagaca aactgtctat cttcatttga tgaaatgcgg taaaatatag
      361 aaaatgaaca ctattggagg gaatttgtaa tggacagcaa aactagaaaa caactgcaag
      421 aaaagttaaa gcaacgtaca cacttgctcc cttccgtctt tcaacagttt ttagaagaaa
      481 atcgttcttc cctttcatta ggcagtcgct atgaatacgc aaaagatttt catctgttta
      541 ctgattattt gagaaaagta ttttctgaag aagtggatga tcagctgatt atccatttag
      601 aaaaacaaga ttatcagaat ttcttagcta aaatctatcg acatactcgt tcgttccaaa
      661 ctacagcgaa ccaagaaacg gagcaattgt ttgaaaatag ctattacggg atttcaagga
      721 agcaatattc attaaatcat tttttacgat ttttgtatca aaaaggactg attgaagaag
      781 agatttctct tttgggtaca agtttaccgg aaacaaccaa agcagctccg cgatatatcg
      841 atgcagaact tttcaaagat tttgagcatt tgtttatccc gattgaaggc tttcaaacaa
      901 gcagagaagc tagctttgaa gaaaagaata gaccgaggaa ccttgcaatt actgccattc
      961 ttctgtattg cggattaaag atccatgaag tagtagaact taaacgtaaa gatgtatctt
     1021 tgaccaagca gattcttaat ctgaatagaa aagaaaacag actgaataaa gtaccaatac
     1081 caaaagaagc gatgccattt ctggagaact attttaagtt aacagcacaa aatacggacg
     1141 aaaattcttt tgtttttcgt tcctcacatg atcagcaaat ttctcctcgg actattcgcc
     1201 aaattttgag caaaattaca gtatataaaa acgtatcgcc agaactatgc agaaaaacat
     1261 atcgttatta tgcagaacta tatttagatg atgctgacgc ggtaaattat ttatgtggta
     1321 atcgatacct ctcatcccat tcttttcaag atatctggga aaagatggtt gatttttctt
     1381 atcacgaatt agcggcattc gttcgggttt cttccatata aaacaaatgt atgatctttt
     1441 tttcacaata aactatgtta ttatataaag gattatgtta cgattatctt gaatttgtat
     1501 attacttaac aaaagataat ggagtgtgaa tgatggagac cataacgtat tcccctttga
     1561 acttatttac gaattttcaa gaagctgcag ctaacttttc cgagaccccg attatctttg
     1621 atgagccact ttcagctttc ccagaattag gacttgaaac aacttacaaa aaatgctgcg
     1681 aaagtgtgtt gaaacgggct tatcaattgg ctcatcttgg agtgaaatcc ggagacaaag
     1741 ttattattta taagagttcc gcttttgaca cataccttct agctgtttct gtgtcttacc
     1801 ttggtgcagt gcctgtcatg acttcttatc atctaccaac aacaacaatg gaagtattta
     1861 tcgatcgttt agaagaccct ttcattttat ttgatgatga gacaaaaaag cgagtgagag
     1921 aaatttcaaa tggaacaaaa tcaaaacaga ttcctaaccc gtggtgctag ttaatttttt
     1981 cctagaggaa aatgtctaaa catgttggta aatcaacaaa aaaacgcata tagtagtctc
     2041 aaaactccca agaaatgagg actacatatg cgttcatcaa aatatactga acattataca
     2101 gatactttta taacattcaa ggaaattatg agaactgttt ctaacatata ccacaattgt
     2161 gtaccagata agattaaaaa ccgaagaaat actgatcaac tgaagcaacg cgatacagtg
     2221 attattgctt gtgttatatg gggcataatt aatggctata ctagccaaag agccacgtat
     2281 agagcggttt gttccgtctt atttcctaat ggtgactttc ctagtaggag tcgattcact
     2341 cgcttaagtt caaacttagc ttacactatc aagattattc gatacttttt catcaagaag
     2401 ctcaccaaag gtgaactagt cggaattata gatagttttc ctagtccatt atgtaaacca
     2461 gttagaaata gacaagcaaa actattgaat caaatagcca aagttggcta taactcaaca
     2521 aaaaaatctt atttttatgg tcttaaaatt catatgatcg ttactaagac tggctttccg
     2581 attacttact caatcacgaa tccaggtgtc catgacgtga aagtgttaga gactttatcg
     2641 gaagaagcga atcttcccaa tatcctaggg gacaaaggat atattagcca taaaa
//
LOCUS       DADVXE010000148         2665 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.155, whole genome shotgun sequence.
ACCESSION   DADVXE010000148 DADVXE010000000
VERSION     DADVXE010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.155"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(46..1239)
                     /locus_tag="KB913_002884"
     CDS             complement(46..1239)
                     /locus_tag="KB913_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6821162.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1303..1683
                     /locus_tag="KB913_002885"
     CDS             1303..1683
                     /locus_tag="KB913_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBB6821163.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1757..2119
                     /locus_tag="KB913_002886"
     CDS             1757..2119
                     /locus_tag="KB913_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821164.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT          908 a          427 c          487 g          843 t
ORIGIN      
        1 gacgaaacct agtaaggtct cgtcctttta ttttgaataa atgatttaat cgattgtctc
       61 taaagcatac ttgattcgat taagtccttc cagtaaagtt tcttctggac aagcaatatt
      121 caagcgcata tgcccatgac cggaaggacc aaacgtgatg ccaggattta atacgacttt
      181 tcctttccga acaagagtgt tctccaattc ttggtcgtct gaaatatagg cggtaaaatc
      241 taaccacatt aagtaagttc cttcagggtt cattattctc actttcggaa gatactgttc
      301 aaaaaactga ttaactgttt gaacattttt ttctagataa ggaatcagtt ggcttaacca
      361 ttctccaccc gtctcataag ccgcttgggt tccaatcagt ccaaaagtgt tgatttcgtg
      421 ctgttggttc atcactaaat gtttttcaaa atcagctttc atctctggat ttttgataaa
      481 taccattgaa tttttgattg cagctagatt gaaagtcttg gttgcggaag taaaagcaac
      541 tagtagatca tctaaattag gatcaatcgt tagcatggaa gtaaatgtat gatcgaataa
      601 agttaaatct tgatggatct cgtcactaaa cagaatcact tgatgtttta aacacaattc
      661 gcttaactgt ttcaattctt ctttgctcca aacacgccct ccaggattgt gaggattgca
      721 taaaatcatt gcttttacat tgttttcttc gatttttttc tccatgtcag acaagtccat
      781 gatgaaatga ttattttttt ctagcaaaga gcttcgaacg atgtgacgtt gatttgtttc
      841 tataatagag gaaaatggag gataaactgg gtcatgaatc aaaatagaat cgcctggttt
      901 tgtaaaagtt tgtactgctg cagctaaact ggttaacaca ccacttgtaa aaacgatatt
      961 ttctttcgtc aactccacag catggtgttg gcgttcccaa tgaatgatag cctgatatag
     1021 tttatcagac agagtggcat aaccaaagat tccatgtttg atgtattcac taaacgcttt
     1081 agctacccca ccgggagaca agaagtccat atctgctacc cacaaaggaa gtaagtcatc
     1141 catttgatat gtctcagcaa ttgcgtccca ttttacactt tctgtatctt ttcttgaaat
     1201 ctgtttatca aattcgatca tcttaagacc tccagtcatt ttcgtcgctt ctttttttga
     1261 gctatttaca gtataatgat aaatgcgaag agagggaagt agatgactta taaaattgga
     1321 caaataattg aaggaaaagt gacagggata cagccttatg gcgcattcgt ttctcttgat
     1381 aacgagacgc aaggacttat tcatgtttca gaagtacaat ccggttatac gaaaaatatc
     1441 cattcattgt taaaagtcgg acagccagta acagttcaga tcatcgacat tgatgaatat
     1501 tccaaaaaaa tcagtttatc tttaagaacg ttagaaaaaa caaatccagc tgttccatat
     1561 cgcagaaaaa ggtatttcac gaataaaaat cgtaagatcg gatttaccac tattgcggag
     1621 cagttaccta tttggataga agaagcatta tctgaactag aacggaaaga aaataagaaa
     1681 taaaaagtgt attttttctg aaaatgtgct agaattttta tgtaagccat agaacaagtt
     1741 gatcgaggtg gaaattttgg caagcaaaag agttgctggt acaattatgt tgcatttgga
     1801 ggatggtact aaaaaatttt tggtccattc aattgatgac aagttggaat ttgcgttagc
     1861 ggaactttct gaaggaaaga ctggtttagc gaatatactt aatttcttaa aagaaatagt
     1921 tcatatcgat gttagcaaga ttagtttgat ggaattgaca aatacacata ttaaagagga
     1981 aaatgttccg ttgtttgtct ttgaaactga acaaaagaat caaagagaag aattaggcga
     2041 aggatatatt tgggaagaac caggtcaaat gcgctctgtt cttggaactt acgaagtaga
     2101 gggagtgcct ttcttctaaa atacagatta agcgaacaaa gaagtttgaa tttttttcaa
     2161 acttcttttt ttattgtttg gtccaaaaaa tacaatgaaa tgttctgcta aagatagttt
     2221 tttagtgcat tttattttca aaatatgttg aaaacggttg tataacgaat aataataatt
     2281 gatcgaaaaa tcatttcaca aagtaatgct taatttatag ttgaccaagg aagaaataca
     2341 tgataaattt aacagcgttg attctgaagt ggatgttata tcacatttct aaaaaattta
     2401 aaaaatagtt attgacatgt tactaacgac atgataagat aactgagtcg ttaaaaaaga
     2461 accacttgcg aagcttgatt ctatcgaaaa aaacttcaaa aaagttcttg acaaataaca
     2521 aacgataagt tatgataaat gagttgctga aagatttcga aaaacgaaat cgaaaaaaac
     2581 ttttaaaaaa gagttgacaa tcgcttgtct ctctgatatg atataaaagt tgctacggca
     2641 gccaaaaacg aatcgggaaa cactc
//
LOCUS       DADVXE010000149         2587 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.156, whole genome shotgun sequence.
ACCESSION   DADVXE010000149 DADVXE010000000
VERSION     DADVXE010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.156"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            60..1118
                     /locus_tag="KB913_002887"
     CDS             60..1118
                     /locus_tag="KB913_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBB6821165.1"
                     /translation="MVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPGLLARQGF
                     IEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQIFYITLSS
                     SRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFSFGTNYAK
                     DFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIWKAALKVI
                     RPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLVSSGIIAF
                     ICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFNKRDVISI
                     VFWYYLGSISYLYLKKEN"
     gene            1120..2190
                     /locus_tag="KB913_002888"
     CDS             1120..2190
                     /locus_tag="KB913_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821166.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            2177..>2587
                     /locus_tag="KB913_002889"
     CDS             2177..>2587
                     /locus_tag="KB913_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBB6821167.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISY"
BASE COUNT          885 a          317 c          403 g          982 t
ORIGIN      
        1 ctttgatagt aatttttcct gcagactttt cacaaagtga agaggaaaaa aagaaaaaaa
       61 tggtgtattt taataatgtt ttcattatca taattttttt agctgcgcta atatctatct
      121 atcaatttat ttttttgatt tcttatcatg tcccaacagg aacgccagga ttacttgcaa
      181 gacaaggttt tattgaacat cggttatttg gtgtctatac aagtccaaat gttggagcta
      241 tgtttggata tacttctatt attttaagtt taattagtgt attaatttca aaaataacaa
      301 aaacgattcg tgttttttat atgatgaatt ttatcgtaca aatattttat attacacttt
      361 cttcgtctag aggtgcccag gtagtaattt gttctttttt agtattattt cttttgttgt
      421 ttgccaattc aaaatttaga aagagcatta gagaagtact acctgtaaaa atcaaatgga
      481 tggtaagcat attattagtt ctattggtat atttttcttt tggtactaat tatgctaagg
      541 attttttagc aacaattcct gtatcgattg atagaaaagt agaagttata gagtcaaatg
      601 aatcagataa aactccactt ccagaaaaag aagtaatatt acagcattct agtgataact
      661 ccgaaatttc agctggtcgt tttacgattt ggaaagctgc gcttaaagtt ataagaccaa
      721 ctttgttatt tggttatgga gagaccgatt tctatgggaa tagcgatgca aaatttttga
      781 aaaaagtaga tcttgatact acagatgtga atgaactaaa aagagcacat ggaaacatgc
      841 ataatggatt tcttcaagta cttgtatcaa gtggtataat tgcttttata tgtatctatg
      901 ctttctatgt gttaaatatc tttagtttac tcaaaacatt ttttagaagt aaagtgaatt
      961 atgcgtttct tggtattgtt ttaattttta tactatctat ttttatagat gaaatggtgg
     1021 aggctcatgt acttttcaat aagcgcgatg tcatttcaat tgttttctgg tattatttgg
     1081 gaagcatttc ttacttgtat ttaaaaaagg agaattaata tgaagacagc tttcattgct
     1141 tggactcctt tacatttgat taatatatta aatgtttatc aaaattttta ccgagaatca
     1201 aaaggagatt tatttattta ttctgaattt gaaaacgcta gaagatatag tgagcgtata
     1261 aaagaattag ggctatttaa tgatgttgtt tttgtgaatc accggaaaat cggttcttcc
     1321 tttaaacgta aaattaactt gttaactaac cataatcaat ttttctcgga tgatttatcc
     1381 gtttatgatg aaatttttat acagggggaa aattatttca caaaaatact tttctccaat
     1441 gtttacaaaa aaaatccaga tgtaaaacta aattatatag aagatggttt gggtacttat
     1501 ttgaagaaga gtatattttc aacaagtaaa aacgttcaaa gagtttttaa aatattaaat
     1561 aaaaatagca tcttcaaaaa aaaaattgac gattattttg tctattgtcc ggaattgtta
     1621 ctttatgatg taaaaaatat aaaaaaaatt cccaaaatag atgaaaacag taaattgatg
     1681 aaaaacatac aatcaatctt tgggatagaa gaagtttttg tcggagataa atgtatcttt
     1741 tttgatcaac ctttattatc tgatggttat ggcatagatg aaacagatat tttcgctaaa
     1801 gtaaatagta tattttctgg aaaaaaagaa actttaatta agcttcatcc tagagcaagg
     1861 acaaatcgtt atggtgaaaa aaacatattg aattccagtt taccgtttga agtcttgcta
     1921 cttgaaaatg acttctcttc aacacttttg attagtccta tatctacaat ttctttttca
     1981 ccatctatga tgtttgaaaa gacgatcaac tctattatgt tggctaaatt aattttaaat
     2041 gaatatacag cattatctga agataaaaaa gaaacattga caaatattgt tcttttctgt
     2101 gaacattata accgtctatc agaagaaaaa attttactcc cagaaaactg ggcagaatta
     2161 agaaagttgg tagagtatgg gattatttaa cacactttcc aagtcaaaat tagttaagtc
     2221 cagtttctgg tatactatag ggaatttttt tattaaggga atttcattca taactattcc
     2281 tatttttgta aatattacta ctcaagcaga atatggtttg attaataatt tcacttcatt
     2341 tgtatcaatt ttttcgattc ttgttgggct aagcctaaat tcggcaatta ataatgcaag
     2401 ttttgactat aaagatgaca taaatgaatt tatgtcatcg gtactttctc tagctacact
     2461 ttcgttaatt gtgttcttat taatagggaa catatatttt ttgttttcaa atgctttttt
     2521 tgatatgaac caacttgtat ttaatttgat gttattacaa agttttgcta gttttgtaat
     2581 tagttat
//
LOCUS       DADVXE010000150         2566 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.157, whole genome shotgun sequence.
ACCESSION   DADVXE010000150 DADVXE010000000
VERSION     DADVXE010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.157"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..78
                     /locus_tag="KB913_002890"
     CDS             <1..78
                     /locus_tag="KB913_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBB6821168.1"
                     /translation="LELFFAVFLFLGKNSLKQTKKKELV"
     gene            complement(108..617)
                     /locus_tag="KB913_002891"
     CDS             complement(108..617)
                     /locus_tag="KB913_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBB6821169.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(729..1727)
                     /locus_tag="KB913_002892"
     CDS             complement(729..1727)
                     /locus_tag="KB913_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6821170.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1928..2512
                     /locus_tag="KB913_002893"
     CDS             1928..2512
                     /locus_tag="KB913_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6821171.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          801 a          475 c          483 g          807 t
ORIGIN      
        1 ttagaattat tttttgctgt ttttcttttc ttaggaaaaa atagcttgaa acaaacaaaa
       61 aagaaagaac tcgtctaaat agacgttttc tttctttttt tgttgaatta ttgagtaagg
      121 cgacttcttt tttctggttc tttgtgtgct aatcgactgg cagcagcagc ggcgatcgct
      181 ccgacgatat catctaagaa ggtatggaca tgaacgccat cgtggctgtt tagttctttt
      241 aaaataccag gtttcacctt gtcgatataa ccataattcg taaagccgat cgtaccgtaa
      301 acattcacga ttgacaaggc taggatctca tcgataccgt aaaggccttc gtcatcttcg
      361 ataatatgtt gcaacggact catcaatttt ttcttttctg ctaatatatc taattggatt
      421 ccagtgataa tggcgttatg tacttcacgc tttgttagca cgctgttgac actttcagta
      481 caatccgcca aagtcaaatc agaaatatag tctttttgta aaaacatgac aagttgtgcg
      541 atatcttcta cagttacgcc acgttccttc aatagttctc ttgccttttc ttctaaagtc
      601 tcagttttga cgaccatatt attgctcccc ctttattttt tctttctcta tttcatgtta
      661 acggaacatg aaaaaaatgc aagaaactgc tttcgggttt aacttgaaat gcaaagagat
      721 ataaaaaatc aactaggacg aagattttta tcgtataagc ttgtgctgtg accaggctga
      781 gttcgttcct ttggattaat atagtgtaaa gcgttgttca ctgcagtagg tgcttcaccg
      841 agcccagtag caatcagttt cacttttcct tcataggtac agatgtcacc agctgcataa
      901 acgcctggaa tagaagtaga catatctgat tttacagtaa tggcatttct ggtactatca
      961 agtccccaag aagaaagatg ttctaaatta gaagagaatc cataattgac gatcagagaa
     1021 tcaatcatca aatcaatcgt ctcgtcactt ttcacttttt ttaaccggat atctgtcagt
     1081 tccccattat tgcctgataa tccatcgatg agatagggag taagcaagtt gacagatgaa
     1141 gatttcaagc gtgatacact atgttcgtgc gcacgaaatt ccgggcgacg atgaatcaag
     1201 taaacttcgc ttgcaatagg ctctaacatc aacgtccaat cgatagcaga atcaccacct
     1261 ccagcaatag cgactttttt tccagcatac ttcatcaaat cattcacgaa ataatccaat
     1321 ccgtggtttt caaatgattc agcattatct aaattcaatt ttcttggctg gaatgaacca
     1381 tttcctaaag ctaaaatgac tgctttggaa taatggatgc ctttatttgt agtaatctcg
     1441 ataacttcgt cttcacgagt aagcgagaga acttcttctt ttaaatggaa tgtatggtta
     1501 aaagtagtta attgtttttc taattgatcg attaattcac ttgcttttat tgctggatac
     1561 ccaggaatat cgtaaatata tttttcggga tacaaagttg ctaattgacc accaagttga
     1621 ggtagactgt caatgatttt tgttttagct tggcgcattc ctgcgtaaaa agcggcaaac
     1681 atccctacag gacctgcacc gatgattgta atgtcataga tttccataaa aattcctccc
     1741 ttttcacact atatcagaat ttaattgaga atgcttctca aaaatgtttg aattcgaaat
     1801 cgaaacggta agttatagaa tgtatctagt gatgaaaaat aaaagaaaac aaatctagta
     1861 tttttacgag aggttaggta ttatgttatt attattatga agtatgcaaa tattaggagg
     1921 aaacaatatg gcattcccac aactagattt aaaaagtgaa aaaggaccaa aagctgttat
     1981 caaaacaaac cgtggtgaca ttactgttca attattccct gaactagcac cgaagacggt
     2041 tcaaaatttc attgaacttt ccaaaaaagg ttattatgat ggcgtgattt ttcaccgcgt
     2101 tattcctgat ttcatgatcc aaggcggcga tccaactgga acaggaatgg gtggcgaaag
     2161 tatttatggc gaaagttttg aagatgaatt cagtcgtgaa ctgttcaacc ttcgcggagc
     2221 tttatctatg gcaaattcag gtccaaacac aaacggaagc caattcttta ttgtaaataa
     2281 cacaaatgtg ccagctaata tgcttggaca actagaaggt gctggattcc catcagaaat
     2341 cattgaagcg tataaaggtg gcggaactcc ttggctagat ttccgacata cagtctttgg
     2401 acatgtacta gaagggatgg acacagtaga tgaaatcgca aatgtacaac gtggtccaca
     2461 agaccgacct gtacatgatg tagtgattga aacaattgaa atttcagaat agtttggtat
     2521 ggtacggagt aattatgaaa aaggacgaaa cctagtaagg tctcgt
//
LOCUS       DADVXE010000151         2560 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.158, whole genome shotgun sequence.
ACCESSION   DADVXE010000151 DADVXE010000000
VERSION     DADVXE010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.158"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..1097)
                     /locus_tag="KB913_002894"
     CDS             complement(<1..1097)
                     /locus_tag="KB913_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBB6821172.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENA"
     gene            complement(1227..2552)
                     /locus_tag="KB913_002895"
     CDS             complement(1227..2552)
                     /locus_tag="KB913_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006702416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6821173.1"
                     /translation="MIILVILSMSTLSLISLSIKDATDRASKETFANITNSFSMEINR
                     QVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLVDYDIIETQETLANQSPE
                     RAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDKNKILMHKDLAEKNNLKV
                     GDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSAAQELYENTLITDIHTAA
                     KVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWREYNLIKSSSNYPALQQSI
                     SGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLLSLGISKLEIFGQFLIEM
                     VFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQSASSQLGGGAEAEGFNK
                     TLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNPKELLIDNN"
BASE COUNT          785 a          488 c          376 g          911 t
ORIGIN      
        1 gcattctcat tagagaacac tccctttttt gtgacttttc tgaagctaga gtgaatactt
       61 tcaactgcat tagtagtgta catgattttt ctaatggcgc tgccataatc aaagagttgt
      121 tcaacatgag aaaagtttcg tttgcataca tctactgcac cagaataatg agaccaccga
      181 ttttgaaaac tgtcgaaggc agcgtgtgca gcgtttaaag aagaagcact gtagaatttt
      241 ttcatgtctc gacagacttc cttataatcc ttacttggga ggtatcgtaa cgcatttcga
      301 acaagatgaa caatacagcg ctgcacaatg acagaaggaa aaattgcttt tgcgccttct
      361 ttgagaccgg aaacaccgtc catcgaaatg aaaaaaacat cttctacacc acgtactttc
      421 agttcatcaa atacttgcat ccagcgattt ttagattctg tttgattgag ccataggcct
      481 aaaatctcct tgtttccttt aagatcatag ccaagaatgg tgtacacagc atattcttta
      541 gcttcatagt tttcgcgtaa agtgacgtac atacaatcaa cgaatagaaa tgcataacac
      601 ttggctaatg gccgagcttg ccattcttcc aattcaggaa ggacggcatc cgtgatatca
      661 gaaatcattt cgtgggaaat atcaaagccg taaatatctt caacggttgc ggcgatatcg
      721 cattgactca ttcctcgtgc atacatggaa agaaccttac cttcgatgtc ggagacatct
      781 cgttttctat taggaatcaa ctcaggttca aaagaagcct cccggtctct gggaacatca
      841 atgtttactt taccaaagct cgttttaagc gtcttattgc cataaccgtt tcgtcgattg
      901 tcatgtttct ttggctcttt agaatgggcg tcatacccta aatggttatt caattctcct
      961 tgaagcattt tttcaaataa gggaccaaac acatctttta aaacatcttg catatcctct
     1021 acagattcgg gttgataagt attcaaaatg gattcagcta acttctcagc atcaggattt
     1081 cttttctttc tagccatcgt gtaatcacct cttgatctta ttttagaaaa ataaaaaccg
     1141 tgaagcaacc acccgcctag gattgatggt tacttacacg gtttatatta cactctcatt
     1201 tttggtgcta aaaagcaccg aaaattttaa ttattgtcaa ttaataattc ttttggattc
     1261 cttcttaata tattgaatga agaaataatc aatgatacaa gaagtactaa actcataaat
     1321 ataactacat aaatcatgaa tttaggtaat acattgatat ctaaacttga taatgtcttg
     1381 ttaaatcctt cagcttctgc cccaccacct aattggctag atgcagattg tttagctatt
     1441 tgtttagcta tatcaccagt aaccttattc aatatattat tcccaagctt gtcagctgta
     1501 tattgagcta agaaatagga accaacgaat gcggggattg atataaatac catctcaatt
     1561 aggaattgac caaaaatttc taattttgat atacctaatg atagtaatac tgctatttct
     1621 ttctttctag cattcatcca taagaataat aataatgaaa ctacaactcc tgcaaatatt
     1681 aatgagccaa aaaataattt atttgaaatt gagtaaatac ctgatataga ttgttgtaat
     1741 gcagggtaat ttgatgaact tttaatcaaa ttatattctc tccaatttat atctaatttc
     1801 ccaagatctt ttattacact atcaagattc ttatcacctt ttacaaagaa tgttgcatct
     1861 tggtatacag ctgtatcttc ggtattacca taaactttag cagctgtatg aatatcagtg
     1921 attaatgtat tttcgtatag ttcttgtgct gcacttactc caccgctatt atgcccatcg
     1981 aatagacctt taatttctac ttctactgtt tcatctgcac ctttctcatt atcagcatca
     2041 aataaattag attttatttt tatcttatct ccaactttaa ggttattttt ttcagctaaa
     2101 tctttatgca ttaagatttt atttttatct tcattttcta aatgctttcc ttctactaat
     2161 ttatatgctt ctgatacaaa ttttgtttct tttgttgagt cgttaacccc agttaacata
     2221 actgttcttt taaaattctt tgctctttca ggtgattgat tcgcaagagt ctcttgagtt
     2281 tcaataatat cataatcaac taaatctgca acactgttta ttctttttac ataggagtct
     2341 atactatctg tttgagatat ctttttaata tcttcacctt ttacatttcc cccacctcta
     2401 ggtgttcctg gatttacttg tctatttatc tccatagaaa aactatttgt tatattagca
     2461 aatgtttctt ttgaagctct gtccgtagca tctttaatag ataaactaat gagacttaaa
     2521 gttgacatag ataaaataac taatatgata attaatgatt
//
LOCUS       DADVXE010000152         2400 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.159, whole genome shotgun sequence.
ACCESSION   DADVXE010000152 DADVXE010000000
VERSION     DADVXE010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.159"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            207..2069
                     /locus_tag="KB913_002896"
     CDS             207..2069
                     /locus_tag="KB913_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6821174.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2400
                     /locus_tag="KB913_002897"
     CDS             2069..>2400
                     /locus_tag="KB913_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6821175.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
//
LOCUS       DADVXE010000153         2317 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.160, whole genome shotgun sequence.
ACCESSION   DADVXE010000153 DADVXE010000000
VERSION     DADVXE010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.160"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            14..2167
                     /locus_tag="KB913_002898"
     CDS             14..2167
                     /locus_tag="KB913_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBB6821176.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          795 a          413 c          517 g          592 t
ORIGIN      
        1 ggaaggatag gaaatgatga aagattttat gaaaaaaata ttaaatactt cttggttaga
       61 aaaaataaga aaaggtgcac aagaacctaa gaacaaaacg tttcgccggt cccatgttcc
      121 ttttcgctta aattttcttt ttttcattat atttacgtta tttgttgcgt tgattgctag
      181 attgggttat ttgcagatcg tgaacggcga agagatggag gcgcgagtga agtctacttc
      241 tacgattacg gtccaagaaa gtactcctcg cggaatgatc tacgactcca caggaaaagc
      301 tttagttacg aataaagcga atcaggccat cacatatacg agaggaacac aagttacggc
      361 taaagatttg cttgaaatcg caacgaagct gaactcgctg atcgatgttc cggtagatga
      421 aaatctgaca gatagagata aaaaagattt ttggctggct gatcccaaac atttgaaaga
      481 agccacaaaa agactttcgg caaaagaaaa gcaattaggg aacagcgaac aatatagtgc
      541 gatggtcaat aaagtcacag ctgatgagat taatttaaac gaggagcaat taaaaattgc
      601 taccatcttt aaacggatga atagtgcata tgaattaaac actgtctata tcaaaaactc
      661 tggtgttact gatcaagagt tagctgttgt ggcagaacgc gcttctgaac ttccaggagt
      721 ttcgactggc acagactgga cacgagaata taatgcagca agttcactga aaagtattct
      781 tggcagtgtg acgactgaaa agcaaggact tccagcagat gaagcagaga aatacctagc
      841 aaaaggttat tctcggaatg accgtgtagg acaaagttat ttggaaaaac aatatgaaga
      901 tgtcctgcaa ggaaccaaaa cccaatatga agtttccctt gataatgaag gaaatgtttc
      961 gaatcaaaaa gaaatcttct ctggggaaaa aggttctaat ttaatgttat ctatgaatgc
     1021 agaattccaa tcaaaagtag aagaaatttt gaaaaggaat tatcaaacat tgatcaacaa
     1081 cggcaaagca cagtattcgc ctggtgctta tgcagtggct atgaatcctc agacaggaga
     1141 agtgctagca atgactggtt tcagtcatga acaaggttcc aaagaaatca ccgagaatgc
     1201 tttaggcacg attactagcg cctttgatcc agggtctgta gtcaaggctg gtactttgac
     1261 agcaggctgg gcaagtaacg cgatcagcgg aaatcaagtt ttgattgatg agccgattcg
     1321 tctgcaaggt gcttcagaaa aaagctctgt ctttaatcga agcggacaag ttgctcttga
     1381 tgcagtcaaa gcatcggaat tgtcttctaa tacgtatatg atcaaagtgg cgttaaagat
     1441 gttaggacta gactatacac ctggaatggg actacctagt ttagatgaag aagctaaagc
     1501 ttatcagcaa ttgagagact ctttcaaaga gtttggtctt ggtacaacga ctgggatcga
     1561 tttgccgaat gaatctcctg ggatctcacg ttctgttgat tatatgaaga agttcaatgc
     1621 ggataatggc aaagaatggt atgctccagg taactttacc gatttggcat ttggacagtt
     1681 tgacacatat acaccaatcc aattagctca atatgcttca acagtcgcta atggcgggaa
     1741 acgagtacag ccgcacctag tcaaagcgat ctatggcaat gacgaaaatg gaaacttggg
     1801 tgaagtgaag aaagaaattg gcacaacagt agaaaatacg gtcaatattt ctgcagaaaa
     1861 tatggcgatc ctccgtgaag gattccacca agttgtccat ggtaccgatc cttacacaac
     1921 agccaaacca ttagccagtg cgaaaatgga cctttccgca aaaacaggga ctgcagaaac
     1981 ggttgcggaa ggtcatccag atattgcgac agtcaatagt aatatcgtgg catacggacc
     2041 aacagacaat ccggaaattg ccatcagtgt tgtcttgccg aacttattag acgaacaaga
     2101 ccacataaac ttgacgattg ctaaagaaat aatggacgcg tattatgata tgttcatggc
     2161 aaaataaaaa agaggtcgtg aaaaagccgc ttagtttcga gtatgaagaa aaattttgtg
     2221 aaaatagctt ctcacatttt tgcttaaatt tgacttcata ccgagaaact ggcttttgaa
     2281 caccgtttac tcggcaaaaa aggttgtgac aaaaatt
//
LOCUS       DADVXE010000154         2317 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.161, whole genome shotgun sequence.
ACCESSION   DADVXE010000154 DADVXE010000000
VERSION     DADVXE010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.161"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            26..1093
                     /locus_tag="KB913_002899"
     CDS             26..1093
                     /locus_tag="KB913_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6821177.1"
                     /translation="MANNDDGLYRFRGMLIKNLVDQGNEVIVSLPKGKNIPKLIELGC
                     QIIETPIDRRGINPKTDFKLFFNYCNILKKIKPDMVIAYTIKPNIYGGLACRLRKVSY
                     ALNITGLGTAFQKKGVLKSLIVFLYRLAAKKSKVIFFENFENMKTFQTLQIAKQSKYK
                     LLNGAGVDVEHFSYLEYPKDEQVHFLFIGRIMKEKGVDELFEAMKNLYSEEKNCVLDV
                     LGYFEEDYGIKIEKYEKEGWLKYHGYQSDIRPFVERAHCFVLPSWHEGMANTNLESAA
                     SGRPIITSDIPGCKEAVIESKSGYLCERKNSCSLYNSMNKFLKLSYEQRINMGKMGRN
                     YMIKKFNKKKVVDETIKSLFS"
     gene            1100..1495
                     /locus_tag="KB913_002900"
     CDS             1100..1495
                     /locus_tag="KB913_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6821178.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            1492..>2317
                     /locus_tag="KB913_002901"
     CDS             1492..>2317
                     /locus_tag="KB913_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6821179.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKTGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKDKIINLIYPKLIEDEHGE
                     YFRPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAVSQFNKQ"
BASE COUNT          907 a          262 c          443 g          705 t
ORIGIN      
        1 gtattataat aaaaaaattc ttataatggc aaacaacgat gatggtcttt accgttttcg
       61 aggaatgctc ataaaaaact tagtagatca aggtaatgaa gttattgtat ctcttccaaa
      121 gggcaagaat attcctaaat taattgaact tggatgtcaa attattgaaa ctccaataga
      181 tagaagagga attaatccaa aaactgactt taaactattt tttaactatt gtaatatttt
      241 gaaaaaaata aagccagata tggtcattgc ttatactatc aaaccaaata tatacggtgg
      301 attggcatgt cggttaagaa aggtttctta tgcattaaat ataaccggat taggaacggc
      361 atttcaaaaa aagggggttt tgaaaagtct tattgtattt ttgtatagat tagcagctaa
      421 aaaatctaag gtcatatttt tcgaaaattt tgaaaatatg aaaacatttc agactttaca
      481 aattgctaaa caaagtaaat acaagctatt aaacggtgca ggagtagatg tagaacactt
      541 tagttattta gaatatccta aagatgagca agttcatttt ttatttattg gaagaattat
      601 gaaagagaaa ggtgtagatg aactttttga agcaatgaaa aacttatata gtgaagagaa
      661 aaattgtgta cttgatgtcc ttgggtattt tgaagaagat tacggcataa aaattgaaaa
      721 atacgaaaaa gagggatggt taaaatatca tggatatcaa tctgatattc gtccctttgt
      781 agaaagagca cattgctttg ttttgcctag ttggcacgaa ggaatggcaa atactaacct
      841 tgaatcagca gcatcaggga gaccaattat tacaagtgat atcccagggt gtaaagaagc
      901 agttattgaa tcgaagtctg gttatttatg tgaaagaaaa aatagttgta gtctctataa
      961 ttcgatgaat aaatttctaa aattatcata tgagcagcgc attaacatgg gaaaaatggg
     1021 gagaaattat atgattaaaa aatttaataa gaagaaagtt gtcgatgaaa caattaaatc
     1081 attatttagt taaaaagata tgttttgcaa agtatgtgat agaaaagagg gattctgtgg
     1141 cttcagaata gatatcaaag aattggcaaa agtttctgat atttttttat ttactacatt
     1201 acaagaagga atgccaagat ctatgatgga agctatggca agtggattgc catgtatagc
     1261 aagtaaaatc cgaggtaatg tagacctttt agtggaagga aaaggtggat atcttgttcc
     1321 agctaaagat gcagaattag tagcagagtg tttgagagaa ctaatcaata ataaatctct
     1381 tagaaagtat atgggaaatg agaacctttc cagaattaaa gaattcgagg ttagtatcgt
     1441 aaaaaaaaga atcaaagaaa tatatgaaga agttataggt gagagtgtaa aatgaaaaat
     1501 ccaatgtttt caataatagt acctatctat tgcgttgaaa aatatttgaa agattgctta
     1561 gattcaataa gaaatcagac atttaaaaat tttgaagcaa tactagttga tgacggtagt
     1621 cctgacgaat gcccagaaat atgtgactat tattcccaaa tagatggacg tttaaaagta
     1681 attcataaga aaaacggtgg aataatagat gcacggaaaa caggagtcac tagtgctatg
     1741 ggagagtata tagtttttct agatggtgat gattggcttg caaatactta tttagaaaaa
     1801 tatgcggaag taattactaa gtacaatcca gatataatat gtagtgggta ttttgcatca
     1861 cgttccaaca aaattagaaa aagagaattg tcttgctcgt ttggatatta tgacaaagat
     1921 aaaattataa atttgattta tcctaaatta attgaggatg aacatggaga gtattttaga
     1981 ccacaattat gggcaaaagc ttttagaact actctgtaca aggaacaaca acaagtatct
     2041 gggcaagtta gtgttggtga agatcatgca tgtacaaaac catgtattta ccatgcaaat
     2101 tcgatatata tgatggaaaa atgtttatat tattacagaa taaacgaaaa ttctataaca
     2161 aaaaaaccac aaccatatta ttgggaagga ccaaaggcta ttggagagca ttttgaaaag
     2221 cagattgata tgaataagta tgattttcaa gatcaagtat atagaaatgt tacacacaat
     2281 ttatttaatg ttgctgtttc acaatttaat aaacagg
//
LOCUS       DADVXE010000155         2185 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.162, whole genome shotgun sequence.
ACCESSION   DADVXE010000155 DADVXE010000000
VERSION     DADVXE010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.162"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..538
                     /locus_tag="KB913_002902"
     CDS             <1..538
                     /locus_tag="KB913_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6821180.1"
                     /translation="YRRSLVLEFNLSFGDNKIIFAEDNWFQLQVFMTNTRICFVDKLC
                     YYYRQQNNSIMHKPKSNLVFRHGNMIADYEKLIRQNGNNIIDKKACMLVAFDVLIMEI
                     FNQKNVGGTCEDYKNALVSLKHHKILRENISNIVRMKAYELEPNMRKKLALVTISIMF
                     NFKMYKTAYNMLWRIYNR"
     gene            552..1631
                     /locus_tag="KB913_002903"
     CDS             552..1631
                     /locus_tag="KB913_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6821181.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     TIIIPNPIKENLPYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIY
                     GEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEAL
                     AIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQK
                     GIKLRKELTSKNISNIWYEYLNQFF"
     gene            1872..>2185
                     /locus_tag="KB913_002904"
     CDS             1872..>2185
                     /locus_tag="KB913_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HBB6821182.1"
                     /translation="MWAFGIGTDRGIGTTVVAYGTGIIPSESDMIMVKWYSCISMFVF
                     HIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIVVPIVFVSKLLEVRIAL
                     VHG"
BASE COUNT          825 a          239 c          416 g          705 t
ORIGIN      
        1 atatagacgt agtttagtat tagagtttaa tttatcattt ggtgataaca aaataatttt
       61 tgcagaagat aattggtttc aattacaagt atttatgaca aatacaagaa tctgtttcgt
      121 agataaattg tgttattatt atcgccaaca aaataattct ataatgcata agccaaaaag
      181 taatttggtt tttagacatg gaaatatgat tgctgattat gaaaagttga taaggcaaaa
      241 tggaaacaac ataatagata aaaaagcttg tatgttggtt gcatttgatg tactaattat
      301 ggagattttt aatcaaaaaa acgttggtgg aacatgtgaa gattataaga atgcattagt
      361 ttctttgaaa catcataaaa tattgagaga aaatatttca aatatagtta gaatgaaagc
      421 atatgaactt gaacctaata tgagaaagaa gttagccctt gtgaccatta gtataatgtt
      481 taattttaaa atgtataaaa cagcgtataa tatgctctgg agaatatata atcgataaag
      541 aggtaggaaa tatgaggaaa ttgacctttg tgataggaat tatgggaaaa ggaggggcag
      601 aacgagtaat tgcgaatttg gcaaataatt ttattcaaga taactgggaa attgatatta
      661 taactatata tgggaatcgg caagactatg aactgaatag aaaaatacag gtacatccaa
      721 taatatgtaa aagttcgttt cgtgcattta gacctttgga acgctttaag gaacttagga
      781 aaaaaataag ggaaatacag cctgatctgg ttatttcgtt ccttgctgat gtaaatatcc
      841 atgtcattat ttcattgtta ggagtaaaac aaaaattaat tgtttctgaa cgaaatgatc
      901 cacaacggaa tccagaagaa ccatggatta ggaaaattag agattttctt tataaaaatg
      961 tagatggaat tgtttttcaa acaccagacg caaaaaaata ttttagtaag atcaatgata
     1021 aaaaagtaaa aacaattata attcccaacc caataaagga aaatttacct tattataata
     1081 aaactacaag tagtaaaaaa tttattactg catgtagatt ggataaacaa aaaaatttgc
     1141 ccttaatgat tgatgcaata ggaaaactta ttcatgaagg atatgagtgt gaactggata
     1201 tttatggaga agggggatta aaaaccgagc ttgaaagtta tatcaaccat aatggattaa
     1261 cagaatttgt tcatctaaaa gaatttacaa ataaaataca tgaaaagatg caaaatgcgg
     1321 caggatttgt aatttcttct gattatgaag gtatatctaa ttctatgtta gaagcactgg
     1381 ctattggagt gccagttatc gctacagatt gtccagtagg tggcgcaaga atgtatttag
     1441 gtgatagaaa tgaaataggt catcttgttg aatgtaataa tctagataag ttaacagatg
     1501 caatgcgtag ggtacttttg gatagagaaa gtgtggtaag aaaagcgcaa aaaggaatta
     1561 aactaagaaa agaactgaca tctaaaaata tttcaaatat atggtacgaa tatttaaacc
     1621 agttctttta accaaaagga ggatattgtg tgaaagaaaa aataaatata ttgatgtttt
     1681 cgttaacgtt agtcgcgttt acaatatttt gcgctttttc attaaatcag aactattggc
     1741 taaattggct tggaatattg atttacttat atgcaatctg tacatggcat tggagaaaag
     1801 gagattcaat attttcatta tacacgattt ttttcactct ttttttatta tttagttatg
     1861 ggcaatgcat tatgtgggca ttcggtattg gaacagatcg tggaatcggt acaacagtag
     1921 tagcttatgg tacggggatt attcctagtg aatcagatat gataatggta aaatggtatt
     1981 cttgtatttc tatgtttgta tttcacatag gagcactctt atttacgaga aaaaccacac
     2041 taagaaaagt tagttggtat gaatctggag atgctgatgc cgatagaaag tttttattta
     2101 aaatagggtg tatcatttct ataatagtag taccgatagt ttttgtttct aaattactag
     2161 aggtacgtat agcattagtc catgg
//
LOCUS       DADVXE010000156         2142 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.163, whole genome shotgun sequence.
ACCESSION   DADVXE010000156 DADVXE010000000
VERSION     DADVXE010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2142
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.163"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..200
                     /locus_tag="KB913_002905"
     CDS             <1..200
                     /locus_tag="KB913_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBB6821183.1"
                     /translation="DECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFFENVVT
                     GKENWNDLYHANEVLKIAEEK"
     gene            201..953
                     /locus_tag="KB913_002906"
     CDS             201..953
                     /locus_tag="KB913_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBB6821184.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            958..1905
                     /locus_tag="KB913_002907"
     CDS             958..1905
                     /locus_tag="KB913_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBB6821185.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          750 a          281 c          426 g          685 t
ORIGIN      
        1 tagatgaatg tatcaatgtt gacttattaa ataataaaat aagttttgaa gaaaacattg
       61 ttaaagaaat gcctgaatct gctaatgata tgtatgagaa ggagttgaaa tatttctttg
      121 aaaacgtagt aacaggcaaa gaaaactgga atgatttata tcatgcaaac gaagtattga
      181 aaatagctga ggagaaataa atggaaattt tatttactat ttgtggtaga gctgggtcta
      241 aggggtttaa aaataaaaat ttgaaatatt tggcaggaaa gcccctagtc catttcgctt
      301 tagcaatgat agatatctat caacaaaaac atcctgaaca taattgcacg acttgtttga
      361 atacggacag taatgagtta gtagaattga cgactaagtt aaatccgtct gtgaaaattg
      421 tagaacgtaa acctgaatta gctacagata ctgtagggaa aattgaagtg atacgtgatt
      481 cattcttaca actagaaaga gaagataata tatttgattt aattatagat ttagatttga
      541 cttcaccttt acgtgaagtt tctaatcttg aagaattaat agatgaacat ctaaaaaatt
      601 tagataaaga cgtctacttt tcagttgttt ctgcaagacg taatccctat tttaatatgg
      661 taaaaagaat tgaaaatgaa gttactatag ttaataaatc aagatacaca tctaggcaac
      721 agacacctga agtttttgaa atgaatgcct caatgtattc ttttaaacct gaatttctaa
      781 aaaaaagtaa ttatattttt gatgggcaat gtgggataat aaaaatgaga gattatctaa
      841 ttttagatat tgatagtgaa gaagatttta aatggttaga atttttgttt cctaaatttt
      901 tagaagattc ttcggagctt caagatatct ataattattt atatcggagg taaaaggatg
      961 agctgttatc ttatcaccgg tggggctggc ttcattggtt ctaccttagc caatcattta
     1021 ggagaagaac atgtggtaat cgtcgtcgat gacttatcaa tgggaaaagt agaaaatctt
     1081 gatatgacga aaaatatcac ttttattgag ggagatgtcg ctgagaaatc cttgatggaa
     1141 gagatcatga aagctaataa atttgattat atctttcatt tagcagcagt tgctagtgtg
     1201 gcagattcag ttgcccgacc agtagaaaca catcgtgtga attttgaaag tgtattaatg
     1261 attttagaat tgatccgcaa gtatcaacct gatttaaaac ggatcgtgtt tagttcttca
     1321 gcggctgttt atggggatga accgacttta ccaaaaaaag aagagtccgt gattcgccca
     1381 ttgacgcctt atgcggttga taaattcgct gcagaacaat atgtgctaga ttattgtcat
     1441 ttatatgatg tacccggtag cgcagttcgt tttttcaatg tctatggtcc aaatcaaaat
     1501 ccgaattctc catacagtgg tgtgatttct attctcgtag atcgctataa gaaacaaatc
     1561 gtaggagaag caacttcatt tacattattt ggtgatggaa gccagtctag agactttgtt
     1621 tatatagatg atgtaatcca agcattactt ttagttgcga atgaggaagc tgcactgggg
     1681 aaacaattca atgttggaac gggtaaagca accacacttt tggaattgat tcatgcaatc
     1741 aatgaaattc tcggtgtaga attgacactt gaatacaaag aagagcgttc gggtgatatc
     1801 catgactctc tagcagatat tactaagatc cagtcaattg gctatcaacc gaaatatggt
     1861 attttaagtg gaatgactaa ttatttgaaa actgaaatca attaaaacat actaagataa
     1921 gattagaggg taaattcagg ctctttgtca ataaggactg atgagttttg taaaatcaaa
     1981 tctgggatag aagggctctt tgtcaaatga tgttggtaaa gagaaatctt agaataattt
     2041 ggacagaaca gaaagaagaa aacctctttc tgttctgttt atttggttaa aaatgttttg
     2101 ccatgacgaa tcataattcg tagtttgaaa ttgtaaaagt tg
//
LOCUS       DADVXE010000157         2131 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.164, whole genome shotgun sequence.
ACCESSION   DADVXE010000157 DADVXE010000000
VERSION     DADVXE010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2131
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.164"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..688
                     /gene="wzy"
                     /locus_tag="KB913_002908"
     CDS             <1..688
                     /gene="wzy"
                     /locus_tag="KB913_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HBB6821186.1"
                     /translation="SIILIWAYTQYKGTFNYKKLIKWLILAVIGIYILNVITKARDGG
                     GLSKLTLKDFTSVFDSDDSPLVDSFFEMGGTMSIITFFLISGNGIYPFANTYLTSLLG
                     SISTRMLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNGGYIGGIVYIFIIGI
                     VIGKILSNSIDNQDIENHPMKMFLAITTANIIMGFPRAASYLIVKNFVYGVLIILLIN
                     FFLQQFNKRL"
     gene            734..>2131
                     /locus_tag="KB913_002909"
     CDS             734..>2131
                     /locus_tag="KB913_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HBB6821187.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWVRKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIK"
BASE COUNT          693 a          297 c          369 g          772 t
ORIGIN      
        1 ctctattata ctcatatggg catacactca atataaagga acctttaatt ataaaaaatt
       61 aataaagtgg cttattttag ctgttatagg aatatatatt ctaaacgtaa taacgaaagc
      121 acgtgatggt ggaggactaa gtaaacttac tttaaaagat tttacatctg tatttgattc
      181 agatgattct cctttagttg attctttttt tgaaatgggg gggactatga gtattataac
      241 ttttttccta ataagtggta atggaatata tccctttgct aatacttatt tgacctcact
      301 cttaggctct atatcaacaa gaatgctatc aatgtttgga ataaagtttg ttttattagc
      361 tgattggttt tctcaggatt atttaggaat cacttggggg actggattct caatgattgc
      421 agaagcctat gtcaatggtg gatacattgg gggtatagtc tatattttta ttattggtat
      481 agtcatcggt aaaatccttt ctaatagtat agacaaccaa gatattgaaa atcatcctat
      541 gaagatgttt ttggctataa ctacagcaaa tattataatg ggttttccta gagctgcttc
      601 atatttaatt gtgaaaaatt ttgtgtatgg tgttttaatt atattgttga taaacttttt
      661 cctacagcaa tttaataaac gtctttaata tttaagctta ataaaaagat aaaacaagtc
      721 aggagttgca aaaatggaaa gaactgctcg gctcaaaaaa aacactattt gggctctggt
      781 gtttcaaata acttctattg tctgtggtat gatcttgcta cgtttgatat taacaaagta
      841 cggatccgag gttaatggaa tgattagctc tattaaccaa tttctacaaa ttatttcttt
      901 tttacaatta ggagtaggcg ctgtaatgca atcaactcta tacaaaccac tagcagaaaa
      961 ggataattta atgataagtc aaatcttagc ttctggaggg aagttttatc ggcaaattgc
     1021 atatattcta ctagtatacg tgggtttgtt acttgcagtc tattatgttc tcgttcctaa
     1081 tgaatttggg agatcatata caatggcaat gattgcaaca ttaagtatta attcatttgc
     1141 tcaatattat tttggtattg ttaatacttt gttattaagt gctgaccaga aaatttatat
     1201 tacgtatatt gcacagacaa tagcatttat ttctaataca gttgcatgtg ctttattaat
     1261 tagtctgaac acagagatcc ttatggtaaa acttattact gctataattt atcttgcttg
     1321 tccaatatat tatagatggt atgtggatcg aaactataat ataaagagga atgtgtcata
     1381 tgataaggaa ccgatccctc aaaaatggaa tggggttgca caacacgtag cttctgttgt
     1441 actagatagt actgatgttg tagtgttatc tatattttct aacctgatat atgtatctat
     1501 atataatgtg tacaatttag taatatacgg agtaaaacag ctattcatgg ctatgacaaa
     1561 tggcgttcag gccttactag gggaactttg ggtcagaaaa gaaatagaag ttctttacaa
     1621 aacatttgca tggttcgaat ggattgtaca tactttgaca gtttttattt ttggctgtac
     1681 cggtatacta atcgttccat ttattcaagt atatacaaga ggagtaacag atgctaatta
     1741 taatcaatta tcattcgcag ctttacttgt aactgctaac gcacttcact gtctgcgtac
     1801 accttatcat gtaatgataa aagcagctgg taaatataaa gaaactcaaa atagttttat
     1861 aattgcttct ttgttaaatt taggtttatc attaattttg gttaaaccac tagggctagt
     1921 tggagtagca ttaggatctc taatttcaat cacatatcat acactttgga gtgcaaatta
     1981 taattcaaaa tatttgctta aatggccgat gaaaaaattc tataaacagt tatttgtaaa
     2041 catcttaact gtagttcttt cttttggggc gacatcacaa ttgaaaatga tgtcaatcac
     2101 atatttggat tggattgttc tcgcaattaa a
//
LOCUS       DADVXE010000158         2058 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.165, whole genome shotgun sequence.
ACCESSION   DADVXE010000158 DADVXE010000000
VERSION     DADVXE010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.165"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..244)
                     /locus_tag="KB913_002910"
     CDS             complement(<1..244)
                     /locus_tag="KB913_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBB6821188.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELI"
     gene            complement(237..1829)
                     /locus_tag="KB913_002911"
     CDS             complement(237..1829)
                     /locus_tag="KB913_002911"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBB6821189.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
BASE COUNT          593 a          424 c          323 g          718 t
ORIGIN      
        1 tgattaattc attatatttt ttttcagtaa ttttatatct tgtttcgtaa ttatcataaa
       61 tagcattttg ttgttcatag acaacaaaat tgctattaga tacaaagaat tctttcttta
      121 aggcactccc aaatggtccc ctccttactc catctttttt atcaagtaag cattcaaact
      181 tacgctgttc ccaagcttcc gtaaatcctg ggaaacgaat ttctggttgt atatcattac
      241 tcatgtttga acacctccag cgcaccttgt aaccacgctt cattttcagg tgttgtttgc
      301 agggaagaga tagcttctaa aagttctttt tctagcactt gctgttcttg tcgtatcttc
      361 ttgatgtcat ttccgacatg aaccatatca attggttctt cttcttcaaa cgtatctaca
      421 tagcgtggaa tatttaagtt atagtcattt tctttgattt catcaaagtt tgccaaatga
      481 gcgtatttct cgacatcttt tctttcagca taggtttcga ggattttttg aatgttttct
      541 tccgataatt tattctgatt ttttcctttg acaaattctc gactagcgtc aatgaataat
      601 acgtctcgag tttggcggtt ctttttcaat acaatcaccg tcgttggaat cgatgtcccg
      661 aagaacaagt tcgcaggcat accgatcaca gcataaatac tgccgtcttc tagtaatttt
      721 tgacgaatga ccccttctgc agcgccacgg aataaaactc cgtgtggcaa gacgatggcc
      781 atagtccctg tttccttcaa atgatagaaa ccatgaagaa gaaacgcaaa atctgctttg
      841 gattttggcg ctaattttcc ataacgatta aaccgagaat cgtctaagaa ggtcgtatct
      901 gctgaccaat tagccgaata aggtgggttc attactactg catcaaatgt gtaaggttca
      961 tctgttggcc aatccttatt caacgtatcc ccattgcgga gattcatttc ttcggcatct
     1021 accccatgta aaatcaagtt catttttgct agattgtatg tcgttgtatt taattcttgc
     1081 ccatgatatt taacgttatc tgggtgagtt aagtagttac gcacatttaa catcaatgaa
     1141 cctgaaccca tggttggatc aaaaacacta aagaatcgtc gttctttttg atccaacgtc
     1201 acgatttgtg ccatcatatc agaaaccata tgaggcgtgt aaaattctcc ggctttcttc
     1261 cctgcttctg aagcaaattg actgatcaga aattcataag catccccgat cacgtcccca
     1321 tcgtgaccta aaacttccac gtcattcaat ttcttaatga cttcggtaat cgtcacattt
     1381 cgttgttgct catctgttcc tagttttttt gattggagat ccacatcatc aaataaccca
     1441 ttaaattgat tgtaggtaga tgccaattgc acaaaggctt tgtttagatc attcaattgg
     1501 aacgttgctt gttttgcttg atccgctaag acgttgaaaa gatactctgg cgaaatcgca
     1561 taccccaaaa tatcaacgat tgttgcaatc agatcttctt ttgattcttc atctgaaagt
     1621 aattcgcgat acaacatcgt ttgtttgctt accgtatcat attcctctaa ggattcatct
     1681 gctaaaagaa ccacttgttc caacaaacgg tcggataaat atttatagaa aatcagtccc
     1741 aataaataat ttttatattc tgacgcatcc attttgctac ggagattatc tgccgcacta
     1801 aataattttt gatttaattc tgcacccaaa aagatacact cctatctctt atttaaagtt
     1861 gctatatacc ctcttatttt agcatactcc cttttagaaa aagcaaaaaa aaaaagaaag
     1921 aaacttattc ttgctaataa actacgcgaa aggagtctaa cgttgtttga tataacttag
     1981 actgatcgtt aacttatttt ttatatttct acatagttat ctttagaacc atttcagata
     2041 catatgaaac aattacat
//
LOCUS       DADVXE010000159         2036 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.166, whole genome shotgun sequence.
ACCESSION   DADVXE010000159 DADVXE010000000
VERSION     DADVXE010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2036
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.166"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..607
                     /locus_tag="KB913_002912"
     CDS             <1..607
                     /locus_tag="KB913_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBB6821190.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELGMICGKLDRQYYSASAISSIVIPPK"
     gene            620..1528
                     /locus_tag="KB913_002913"
     CDS             620..1528
                     /locus_tag="KB913_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBB6821191.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            1528..>2036
                     /locus_tag="KB913_002914"
     CDS             1528..>2036
                     /locus_tag="KB913_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821192.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGV"
BASE COUNT          699 a          278 c          460 g          599 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtatgatttg
      541 tggaaagtta gatcgacagt attatagtgc aagtgcaatt tcttccattg tcataccacc
      601 aaaataggga ggtgatttaa tggcaaagtg gaatgtcata ttaagtacaa cagaacccta
      661 taattacgtg gggatgattc aagttcgaca aggcaataaa aacactgaag ttatggaagc
      721 tacaattgtc gaaaatggtc ttccatatga tttatcagaa tgtaaggtat attttgaatc
      781 agttgttggc ggaaaatatc cagtccaatt agaaacaaaa attgtggatg ctaaaaaagg
      841 gaaaatcaaa tatatttttg ataaatattc catgcagtgt ttgcatcgac aaacagccaa
      901 tttcattata tttaaaggag aagacttgat tggaacaact caagacttct cttattttgt
      961 catcaatgct gtttcaaaaa cagaaggaga aatgggttct tattggcaat caattgaaga
     1021 tttaattgct gatatgacag attttattaa tgaaaataaa ggcgatttta cggactggat
     1081 gaatgaaagg aaagaagaat ttgatcgctg gagagaggaa caggagaata gtttccaaga
     1141 ttggagagaa ggacaagaat cagattactt gtcatggttt gaatcaatca aggatatttt
     1201 gaagtctatc gatccaggtg gagtaatgtt agccgaatta atggatgcac gtgtagatct
     1261 tcaaggtgta cgccatgaat cgatttctga acgtttccta tccgatctaa attatttgta
     1321 tcaaaaaatg aaagcagcac ttttcacgat tgaatacggt gaaattgaag tgactgatat
     1381 tcttcaagac gatctctttt cagataatca cgaagtcgaa aaaattgaaa cagtagaatt
     1441 tccaattgaa gaaggagctt tgattattgc aactgttgat gatccaaaac agaatgtttt
     1501 cactcttgag aaagttgggg tgatttgatg gttaaagtaa agagaatgat ggaaactgat
     1561 gaatctggtg ttaaacgtca atttatgcca attacacatg tctctgcagt tttaggctta
     1621 gaaaaaatga tatcaggaca atcaaaagtt ctttcggtta atggtaaata tggtgcagtc
     1681 attttaacga aagctgattt aggattagag aatgcaatta ctgaactacc ttatgcaagc
     1741 gagacaagcg atggtattct tactgctgaa atgtttcaaa agatcgtaaa tggagaaggt
     1801 ggaacatata ttttgccgat tgctactcct gaacaattag gaggtataaa agttggggaa
     1861 ctcttagaag ttactgaaga aggtgtttta tctgcaacta agcaaacaga cttcaatttc
     1921 tctgaagaat taaaaggaaa attagaatct ctaaaaatat taaaagcagg tgcaaatata
     1981 tcaattgcag aagatggaac aattagttct acaggtggta gtgggactgg tggtgt
//
LOCUS       DADVXE010000160         2031 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.167, whole genome shotgun sequence.
ACCESSION   DADVXE010000160 DADVXE010000000
VERSION     DADVXE010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.167"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            81..2003
                     /locus_tag="KB913_002915"
     CDS             81..2003
                     /locus_tag="KB913_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBB6821193.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
BASE COUNT          798 a          273 c          352 g          608 t
ORIGIN      
        1 tacattaatc aagaactttc ttctgtatga aaatagagat aataattgta cacttaagct
       61 gtattcagga ggtgaagata atgggcatcg aatttagcga acggcaaatg aaaatactat
      121 actttttgat tgaaaatgag cacacaactt acaaagaatt atcagaacaa ttatatgtat
      181 ctacgaaaac aattagcaaa gatattttaa ttttgaaaga aataatccaa aaaatgccag
      241 atgtacaaat gttggttcaa cctaaaaaag gcgtttcgct tattggaaaa aaagaaacac
      301 ttcgaaattt attatccagt cataaaatca atatcgcaga ctctccggag gaccgtctaa
      361 cttatgtgtt tgctaaatta ttgaatacta atgattctct aaagattcaa aatcttgctg
      421 acgaattata cgtgagcagg tcgacggtag aaagcacaat gaaagatgtt agaaaaagac
      481 taaacaagca tgggatgtcc ttagtttcag atcgaaatgg cgtgcgcatc aaagctgatg
      541 aaaaaagtaa aagaaggttg atgtcagaag ttgtgaacta ttattggggt ggctttacag
      601 catctaacag taaaacagat ctcttagact tgaatatcaa tttcattggt gaagcgaata
      661 atttcttaaa taaggacata ttgaaaaaag tagccgaatt gcttaatcga tacatgaata
      721 agacacaatt gaaatttaca gattatgaat ttcaaacttt agctatccac cttgctattg
      781 cgatagaaag gattgaaaca agcaatttct tatcacgtag taataattct gaagaagaaa
      841 tctcaaagaa tacacttatt ttaatcaaaa tgattgaaaa agcattttca attattgtgc
      901 caatagatga acaagcttat gttgacattc acattacttc gattgaaaaa aatgctatga
      961 atcacgactt agatcaaacg aagctttcct atttagatat gggtgttgag ctacaagagt
     1021 tagtaagaat taaattaaat gaattttatc ctgatgaaga attgatcaat aatctagtat
     1081 tacatctcaa tgcagcagtt aaaagactca aattgggagt aaatatctat aacccttata
     1141 cggacaaaat caaatattct tttaaaaggt catttatgat aagtgtagat ttattagagg
     1201 aaatcgaaga gagattctgt atacatttta atgaagatga aatcgcttac gtaacactcc
     1261 atattcaatc acttttggat cgttacaaac ctgacaaaac gaaagtgata ttagtttgta
     1321 gtagcggata tggaacatca aaattattag agcaaagaat aaataacggt tttgcagata
     1381 tggttgagat agaagatgta ctaagcatca atgaactaca agatagaaaa gtcactgatg
     1441 aacttgttat aagcacgatt ccgattgaaa atacaaattt tcctgttatt gttgttagtc
     1501 ctttgatgtt aggggcagat gtcagaaaag taaaacagta tctacagtta aatgaacaaa
     1561 cagaagatgc ttttctaaat ttattagata aacgattttg cttttttacc caccaaataa
     1621 aggataatca agtgaacgtt ttaaatataa ttaccaaaaa attggtaaaa gaaaattacg
     1681 cgaaagaagg gatactagag ggagcaatca aaagagaaaa actatcttca acagcgatga
     1741 atgattttgc tatgccgcat atcgaagtag attttataaa aaagccagta atctgtgtct
     1801 acgttaatcc agaaggaatt gattgggatg ggacacttgt tcattctgtt ttcttttttg
     1861 cacttaatga aaaagtaaaa cctgaattga ataaaattta tgaaacattc aatgaaatcg
     1921 cttcgaatca tgagttatta gcaaatttaa aaacgagttc gtcgtttgaa aaattagttt
     1981 atatattgaa agaaggctta taaatgatca gtgaaaaaat caatataaat a
//
LOCUS       DADVXE010000161         1994 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.168, whole genome shotgun sequence.
ACCESSION   DADVXE010000161 DADVXE010000000
VERSION     DADVXE010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.168"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            611..943
                     /locus_tag="KB913_002916"
     CDS             611..943
                     /locus_tag="KB913_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBB6821194.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            1562..1903
                     /locus_tag="KB913_002917"
     CDS             1562..1903
                     /locus_tag="KB913_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBB6821195.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT          689 a          269 c          422 g          614 t
ORIGIN      
        1 tttgcatact cctttttttt gagttataat aatacgcgaa gagagataat ttcattattt
       61 aaacaagcta aaaatcttga tattacttct tttcaggcaa tacgaatatt attcgcttac
      121 attttttgta taaatttaat tgtctgctat gcttgtgatg aattgatttt cgttttgcac
      181 ttttggatga taaatttgga caattgaaaa tacaaaaaaa agaaaggcgg tatgaactcg
      241 gaaggctggt aaccttcgtc agcgttcata cacggcatta agatttggcc cttaatgcgt
      301 taacctttca gtgttacggt attacccgca atggatttag tataacagat attcaaaagt
      361 gataccactt tttttggctg tgttaaggtt aaaaatacgt gatattacga tgaatctatg
      421 cctaagcata atgttataaa aatgtccgtg tggctctttg ccgtatgacg aacgctgaaa
      481 ttagagggaa cgcatgtttg gatgcgttcc ctcttttttg tttgtcatga acgaaaatca
      541 attctctatt tttgaaaaat aacaagaaaa acttgttaaa aatatttaaa gaaattgggt
      601 ggtttatttt atgtcatata caggaatttt gagtctcaaa gatatttgtc actacggtaa
      661 acggtgtacc gctacagaga aaatcacgaa gaaactatca actggccaaa gtaaaaccgt
      721 tgtgcagtgt aagaaatata taatccagaa agacaaagtc tcagaggaaa tgatttatta
      781 cattgggaaa caaaagcaaa taattttaaa agatcctatc cccttaaaag agctatatcc
      841 aacaatcaaa catgtttatg accaaaacgg tgtactgatt ggtcgaagaa aaaatggagt
      901 cttgcgttgt accgcaaaag ggatggggcg tttgatcggc tgaattgatc attctcataa
      961 cttgtatttt atcgtttttc gcttgcttga aaatattgtc gagacttcta aaggaactta
     1021 gagtcactag aaaaataagg agtagacttg atctatcaac aattcccttc ggggagtgac
     1081 ggggtaggtt ttaacgattg gtaacgtaaa aaattggtca atcgagtaaa tgcgcttgtt
     1141 tggatagtgg tgaaatgaat ttgtgtaaat aataagcgca gagtaaacaa gagggaattt
     1201 agaagttaga caagttagaa tagcgtctag attaatcatg agcagctact aagggatcta
     1261 gactttgacg caaactcatg gaataaggag taggtcttct cgtaatgggg aggacgcaca
     1321 agaaattgtg tcgtgtgctg cagtacatgt agatacttgc gaggacgttg attattggat
     1381 caatcgagca tttaccgctg tctactaggg tttctcgttt cggacgccat aaacgagtcg
     1441 aaatttttta tgtattttta agtaaacgaa aaacgataaa atatgaacaa gtcctgaata
     1501 aagtgaaaaa attgatataa aacatagaga aaatgaaatt tacgtaatgg aggaatgaca
     1561 aatgaaaaat tatgatccga atatacgatt gggcacacat actattaagg tttctttcca
     1621 acgttgggat tacaaaggat ttgtgacgtt tagaaggggc ggaaattgta aaggattaga
     1681 tgttttagca ttagacgagg atgatttata cgatcaaaca ttgactgata atccaattgg
     1741 attcggcttg ctacctgaag atgatgaagg taatgaatgg tttaaaatga cgcttatgaa
     1801 tgataatgga gacgaattat ctgttgaaga tacttggtca tatttgagtg attatattgt
     1861 cagctttgaa atcattgaat ttgtagcgga taaagaagaa taaaaactgg aggaataaat
     1921 tttacagata aaggcttaga aggagtcacg acgattaata aaaaggtagt attaccttag
     1981 gcattgagta agga
//
LOCUS       DADVXE010000162         1952 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.169, whole genome shotgun sequence.
ACCESSION   DADVXE010000162 DADVXE010000000
VERSION     DADVXE010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.169"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            70..552
                     /locus_tag="KB913_002918"
     CDS             70..552
                     /locus_tag="KB913_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821196.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            749..1639
                     /locus_tag="KB913_002919"
     CDS             749..1639
                     /locus_tag="KB913_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBB6821197.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT          635 a          335 c          406 g          576 t
ORIGIN      
        1 tccccctaat ttttttagat agaaaattgt atagtatgat gagagaaaaa gtagtttggg
       61 ggaacgttaa tgagaagaaa agcagtaatc gatcggcttt atttattttt ttggtttttt
      121 cctatcgttt tgctaccttt tacatgggta aatgctgttg tacaaggtgc ggagatatta
      181 ggcctgatcc aaggaagcgg atttgtggtt tctaggaatt ttccagcttt gattgttttc
      241 tatttagtga taagtgtagg tctcttatta ccaaaatctc tgatcaatca ctacaattgg
      301 cagctgcttt acttttcttg cttattagta tttacatcta cgttttcttt gctgcctcgc
      361 ttgattatcg gccctaatgg tttgagcgag agtggattga aggatttagc ttattcctcc
      421 atgtatttct tgacgatcaa accatggttc tatttagtaa ttgcctcatt tattcttgca
      481 acattttttt acttctggac agaaatcagg ataaaaagtg aacgatctgt atctataaaa
      541 aataactatt gatggtggat catcagtaaa aaaacatatg agctgcgtaa aatgcatgtt
      601 tctcatatgc tttttttatt attatgtaaa gaatgcgaaa aacgtttaca tgatttttac
      661 ataacttaac tatattttta cagcaaccat acgagggatt tacagtcgac tgataaactt
      721 tagttgtaaa taagaaagga gcaataaaat gaaaaaagta ttgtttactc taggtatgat
      781 gggaattctt ttagccggat gcggctcagg atcaggaaat acagatggct ctgccacaca
      841 aaataattca agtgactcaa atgaacaagt aaaaatcgtt gcggtaggtt cgacagcatt
      901 acagccgtta gtcgatgcag cacaagaaag ctttgtacaa gaaaatccaa attatcaaat
      961 ctctgtacaa ggaggaggaa gcggaactgg tttgagccaa gtcgaagctg gagcagttac
     1021 tatcggaaac tctgatgtat ttgcagaaga aagagacgga gttgatgctt caaaattagt
     1081 ggatcataaa gtagcagtgg tcgggatggc accaatcgtc aataaagata cagatgtcaa
     1141 agatatcacc aaacaggaat tgattgatat ctttacagga aaaatcacta actggaagga
     1201 agttggcggg aaagatcaaa aaatcaacgt cgtgaaccgt gcaaacggca gcggtacccg
     1261 cgcgacattc gaaaaatggg gactggatgg tgctacccct gtgcagtccc aagaacaaga
     1321 ttcatcagga acagttcggc agctggtaag tcaaacacca ggagcaatca gctatttagc
     1381 tttctcatat ctcgatgatt ccacacaagc actaagtatc gacggtgtag aaccaaaaga
     1441 agagaatgta gcagataaca gctggggaat ctggtcatat gaacatatgt acacgaacgg
     1501 aaaaccttcc cctgaagtcc aaaaattctt agactacatg atgacagaag aaatccaaga
     1561 aggacctgtc aaagaattgg gctatttacc aatcacaatg atggaagtag aacgtgatca
     1621 cgaaggaaat atcaaataac tagcagataa acatgccacg gtagtcgtta ctattaagga
     1681 aaaatcaact atgtttcccc acatatacat ttttccttta attgtgaaaa atagttcctc
     1741 atattttgcc gttttttgag ctaataccga gggtcagctg attgaacacc gtttattcga
     1801 aaaaaagagc tacgacatag aactgtcgta actttttttg gctcttcgtc aaatcgtgtt
     1861 ggtgaagaca aatttgaata aaacttagac cgatatgcgg cgcgttctgt gcgccgcata
     1921 tttttttagt tttcaaagat cagaccttgt tg
//
LOCUS       DADVXE010000163         1897 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.170, whole genome shotgun sequence.
ACCESSION   DADVXE010000163 DADVXE010000000
VERSION     DADVXE010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.170"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(16..273)
                     /locus_tag="KB913_002920"
     CDS             complement(16..273)
                     /locus_tag="KB913_002920"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821198.1"
                     /translation="MSTPSRGIKNTPVLTGVWVTDRLDFNWCQKLMSRKGDEILAIYG
                     YSRISTSNQDYKTQIQTLENAGAEIIFLENHWIIEHLWKYF"
     gene            complement(341..796)
                     /gene="tnpA"
                     /locus_tag="KB913_002921"
     CDS             complement(341..796)
                     /gene="tnpA"
                     /locus_tag="KB913_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBB6821199.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1039..1897
                     /locus_tag="KB913_002922"
                     /pseudo
     CDS             1039..1897
                     /locus_tag="KB913_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          603 a          369 c          355 g          570 t
ORIGIN      
        1 caatacttac gtaactcaaa aatacttcca aaggtgttcg ataatccagt gattttctag
       61 gaagattatt tctgcgccag cattttctaa tgtttgaatt tgtgttttgt aatcttggtt
      121 gcttgtgcta attcttgaat agccgtaaat tgccaaaatt tcatcaccct ttctggacat
      181 aagtttctga caccagttaa aatcaagtct atcagtaacc catacacccg tgaggacggg
      241 tgtattttta atccccctag aaggggtcga cactcgctgc cccttaaaag gggattttta
      301 aaagaccgcc aactgctcat cttcactcac ttacttctct ttatttttta aatggttcta
      361 cgtactctct tttacttata atatatcgaa tgcgatcatc agcttcttgt tcacggatgt
      421 atttttcatt tgtcttttga ttcaatccga ctgtactcac atagtatctc ttcgaccaaa
      481 aggatttgtt tccgtattta tatttgagat ttgcgtgctg ctcgtggatt agtaccgcac
      541 tacgaccttt cagatacccc ataaaactgg atatacatat ttttggtggt actcgaacaa
      601 gcatgtgaat atgatctagc attgcatgtg cttctatgat ttccacatct ttcatttcgc
      661 acaacttcct aagtattttt ccaagatctt ttcgtaattg cccatagatt acttttcgtt
      721 gatattttgg tgtaaaaata atatgatact tacaattcca acgagtatat gctaaacttt
      781 tatcgtcatt tgacatgaaa aaactccttt cgatctgatg agcggttggt agccactcac
      841 tagtatatcg aaaggagttt ttatcgctaa agatacttct tccacgcgta gaaacgcgcg
      901 gttttcttgt ttcgcacgct ttacgcacaa aactgactga agtcattaag aaaataaaag
      961 ggtctaaaac ttttaagttt tgtaccgacc cccaaaagtt agaccaaaaa atctaacttt
     1021 tggaggtcgg tattttttat ggctaagtat acttttgaac ttaaattaaa gatcgttcat
     1081 gattacttgg atggtaaagg cggaagtgat tatctggcaa agaaatattc cattaaggct
     1141 ccatcacaag tgaagcgctg gatcaatgcc tatcaagaat ttggtgaaga gggtctagta
     1201 agaaagcgac aaaagaaaaa atattctgtt caatttaagc tggatgcgat agagttatat
     1261 ctaacaagtg agctgtccta tcgtgaagtt gccaacacac ttaacatgaa caaccctaat
     1321 ttgatcgcta gttggatgcg tcaattccgt gagggtggga tcgatggact ctcaaaaacg
     1381 aaaggatgtc cacctatctt gtctaagaaa aatgaaccca aaaataagaa aaaatctaca
     1441 actaaagcaa cgtctaaaga acgtgaacgc atcgaggagt tggagaaacg agtccgttcc
     1501 cttcaaattg aaaatgcctt tttaaaagaa ttgaggaagc tgcgaaaaca ggaagcccaa
     1561 caacgacgaa tgaagcaatc gcacgaatca tcgcaagcct ccgaggaccg tttaaattag
     1621 ttgagcttct agaaacttta aagttcccta aggcaatctt tatgtactgg caaaaacgat
     1681 tggaccgtaa aaatccagat caagagattg aagcggaaat gcttaaagtt cgggagaagc
     1741 acaaggatta tggctgttta cggatgacca atgaactaag aaaccgcggt ttctctatca
     1801 ataaaaagaa agttcagcgc ctgatcaaga agctaggaat aaaagtaacg acatacacac
     1861 gtaaatcacg gcgctacaat tcttatcgag gacaagt
//
LOCUS       DADVXE010000164         1823 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.171, whole genome shotgun sequence.
ACCESSION   DADVXE010000164 DADVXE010000000
VERSION     DADVXE010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.171"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..635
                     /locus_tag="KB913_002923"
     CDS             <1..635
                     /locus_tag="KB913_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6821200.1"
                     /translation="EITYENILKDINFDVKVGDVIGLVGKNGVGKTTLLRILMKIIRP
                     TKGKIIENKKNLSSPFLVMQEMDYQFFTESVRSELALGNEIVSKDQQEKILKKMELYK
                     MKDQLPFDLSGGEKQRLLVSIASLSKTNLFLFDEPTSGLDYINMERIADLIKDLKEKG
                     AVVIATHDPEFLYKTCNRIIYLKNGGIKKDIKLRVEDSTLIEQIFNDITK"
     gene            653..1222
                     /locus_tag="KB913_002924"
     CDS             653..1222
                     /locus_tag="KB913_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBB6821201.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            1332..>1823
                     /locus_tag="KB913_002925"
     CDS             1332..>1823
                     /locus_tag="KB913_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6821202.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIA"
BASE COUNT          611 a          234 c          350 g          628 t
ORIGIN      
        1 aagaaattac ttatgaaaat attctaaaag acataaattt tgatgtcaaa gttggagatg
       61 ttattggttt ggtagggaaa aacggtgtgg ggaaaacaac cttactaaga atactcatga
      121 agattattcg ccctaccaaa ggaaagataa tcgaaaataa aaaaaatttg tcatcgccgt
      181 ttttagtaat gcaagaaatg gattaccaat ttttcacaga atcagtgagg agcgagttag
      241 ccctggggaa tgaaatagtt agtaaagatc agcaagaaaa aattttaaaa aaaatggaac
      301 tttataaaat gaaagatcaa ttaccgtttg atttatccgg tggagaaaaa caaagattat
      361 tggtttctat agcttcattg tcaaaaacta atttatttct atttgatgaa cctacaagtg
      421 ggttggatta tattaatatg gaaaggattg ctgaccttat taaagactta aaagaaaagg
      481 gtgcagtagt tatagctact catgatccgg aatttcttta taaaacatgc aatagaatta
      541 tttatttaaa aaatggtgga ataaaaaaag atataaaact tagagtagaa gattcaactt
      601 tgatagaaca gatttttaat gacataacga aatagaattg aggagaatat atatgaaaac
      661 aaaagattat atttttattg gtttagctac agttatttcc ctagtaattt actttttttc
      721 aataatggtt agtagtattg gtggggcgtt tggtcacagc atatcccccg ggatttttgg
      781 attattatct ggaatcatat ttgtttatat tagctataac taccctagaa aaggaatttt
      841 tactatttac acaattgttt tattgttatt ttttacgtta atgggcgggg cgtacttacc
      901 ttggtttatc agttcgatta gtatggcgat cttagctgat attattctat ctgtatttgg
      961 atatgatcga gcaattcctc aagttgcgtc ttgggctcta atgcaattag gcagtgctgc
     1021 cggacagtgg attcctatat ggttctttac agatcgtttt cgtcaagatt ggatagataa
     1081 aggacaatct gctgcaacaa tggatgcaat gatccactat gcggtaggta tatggggaat
     1141 catttcagtg ttagttgtag caagtttatc tatgattggt gtattgattg gaagaaaagt
     1201 cttaaaaaaa tacaaaaaat agaacgtagt ttacctttta tctgtttgta catctctaat
     1261 ttacgctatt acggaaagca ttaacagttg taaacgaata agagaagaaa ttgaatgcgg
     1321 gggaggaaaa aatgaaagta tacaaaaaat tatttagtta tgtccctaaa atgaaatact
     1381 acggatggtt agccacttta ttttctgatt tttctgtcgt attaacagtc tatggatatt
     1441 acagtattta caaatttctt cagtctctaa ttattgtagg agatgaatat ttagctaaga
     1501 gttatgcggt tcaaactgtt gcttggttaa ctttaggagc tttattttat attttttctg
     1561 gcttattttc tcatatcctt gggtttcgct tagagactaa tttgagaaaa aagggaatta
     1621 gcggtttaac agaagcaagt tttcgttttt ttgatttaaa ttcttcggga tatattcgaa
     1681 agacaattga tgacaacgcg gctaaaacac atatggcaat tgctcacttg attccagata
     1741 gtgctcaagc catagtaaca cctgttttat cagttgcctt aggctttttc attaacttta
     1801 aaattggatt ggttctaatc gcc
//
LOCUS       DADVXE010000165         1712 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.172, whole genome shotgun sequence.
ACCESSION   DADVXE010000165 DADVXE010000000
VERSION     DADVXE010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1712
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.172"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(140..1288)
                     /locus_tag="KB913_002926"
     CDS             complement(140..1288)
                     /locus_tag="KB913_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6821203.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(1305..1709)
                     /gene="tnpA"
                     /locus_tag="KB913_002927"
     CDS             complement(1305..1709)
                     /gene="tnpA"
                     /locus_tag="KB913_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HBB6821204.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          505 a          296 c          272 g          639 t
ORIGIN      
        1 taaacctgac ggttcttaac gcttgaagtg ggagcttctt gggaatagag catacttgat
       61 agcgtatttc tttactaaca gcggtgtctc ttatttacca agctatcccc gtagttccta
      121 cggttcttga tgattggatc taagccaatc ccatagaatg tagtcttaga ccttcggtca
      181 gaatattgat actagcattg atatcacgat catgatgagt atgacaaaca ggacaagtcc
      241 attctcgaat ttcaagagat ttcttgccat ctttatgtcc gcactctgaa caaatctgac
      301 tagacggaaa ccatttatct actttgatga tttttcgtcc ataccagtca gccttgtatt
      361 gtaatttagt cacaaacttt gaccaagaaa catcagaaat acttttagct aatttatgat
      421 ttcgcaacat accttttgtg tttaagtctt caatacagat aatatcgtga tttttgatca
      481 tttctgtact caacttattc agaaaatcag tacgttgatt cattactttt tcatgcaatc
      541 tagctacttt gcgtttttgt ttttgataat ttttagcttc aaatagattg gtacctttat
      601 ttttagccaa taaagcacgc ctagacaatt tgcgttgttc acgctttagt ttcttttcca
      661 ttttggacgt gaatttatta ttatcaattt tttgtccatc agaaagaatc gcaaagtcca
      721 taatacctaa gtcaatacca attgtggaat tagttttagg taattcgata atttcttctt
      781 tacacaacaa agaaatatag tatttaccgc tagaatgacg tgatattgta gcagatttga
      841 taatcccttt tggttgtcta tgaagcttaa ttcttactaa tgacttcaat ttaggaactt
      901 tgatgaattt actatcaatc aaagcaactg taccattttg attattcgtt gtataactct
      961 gaacaggatt tttcttactt ttgaaacgtg gaaatccaac ggatttatcc cgaaaaaaat
     1021 tcttgtatgc tttatctaaa ttaagttggg cattggctaa agcaaggcta tcaatttctt
     1081 tcaaaaacgg aaattctttc ttgtatttag ctggtgtcgg aaaagtcatt tttttagaag
     1141 aatcattttt aacttcttca tacgcctttt ttcggtcatc aagcattaga ttgtagacct
     1201 tacggacaca accaaaagat ttggcaaaga agatttcttg ttcctctgtt ggatagattc
     1261 tgaatttgta tgcttttagt tgttccataa agttcaccta ctttctattt atgattgttt
     1321 ccttgatttt ggatatactt cttaatcaca tcaattggtg cgccaccagt tgtcagaaga
     1381 caaaaacttt tagaccagaa catttctttc caaagaaatt gtttgactct tggaaagtca
     1441 cgttttatca atcttgagct ggcactttta taggcattga tgaattttgt caattctgtt
     1501 ttaggttgag ctttgaacat aatatgaacg tggtctttat catgattcca ctccactaaa
     1561 gtaatgtgat acgattctga aattctttca aaagtagttt tggcataatc agatatttca
     1621 tcatcaatca cttgtctacg atatttcgtt actaaaacaa ggtggtaata aagaagaaat
     1681 actgaatgat tatttgtatc taattccatg tt
//
LOCUS       DADVXE010000166         1705 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.173, whole genome shotgun sequence.
ACCESSION   DADVXE010000166 DADVXE010000000
VERSION     DADVXE010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.173"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            316..570
                     /locus_tag="KB913_002928"
     CDS             316..570
                     /locus_tag="KB913_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6821205.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="KB913_002929"
     CDS             571..888
                     /locus_tag="KB913_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBB6821206.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1447..>1705
                     /locus_tag="KB913_002930"
     CDS             1447..>1705
                     /locus_tag="KB913_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821207.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTN"
BASE COUNT          598 a          258 c          324 g          525 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 ggcaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaaccgt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgacg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacatc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt
     1501 actactttca aaagattatc cgagttaatg cagcagactg ttaaaagtgc tatgcctgaa
     1561 ggatacaagt ttaattttgt tcaatcttca gtatctactg aaagtatcta tttttcaatt
     1621 ctttctgaga gtaggctttt tcattttaga ataagttctc atgtaaagaa aactgatgtt
     1681 gatatatata cgttccgtac aaata
//
LOCUS       DADVXE010000167         1637 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.174, whole genome shotgun sequence.
ACCESSION   DADVXE010000167 DADVXE010000000
VERSION     DADVXE010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.174"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(1..316)
                     /locus_tag="KB913_002931"
                     /pseudo
     CDS             complement(1..316)
                     /locus_tag="KB913_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            591..1133
                     /locus_tag="KB913_002932"
     CDS             591..1133
                     /locus_tag="KB913_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821208.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            1289..>1637
                     /locus_tag="KB913_002933"
     CDS             1289..>1637
                     /locus_tag="KB913_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBB6821209.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          598 a          216 c          312 g          511 t
ORIGIN      
        1 gaatatttat gcttgttggc atcaattact tgtcttttcg tccgaatatc agcgccgctt
       61 gctttaaaat atcattctcc atttcgagtt gcttattttt ctttcttagt gcgatcaatt
      121 ctgcttgttc tggtgttaag ttgtctcttt ctttgaatga gcccgttgat tgtgcttgct
      181 tcatccattt atcgaaagaa gaaggcgtaa gctcatactc tcgaataatt tctgcgcgag
      241 gcttaccagc gagatagaga tcgacgattt gttgtttgaa ttcttttgaa taggttcttc
      301 gttgacgtct tggcatgaaa aatcctccag tgtgtttttt attattctac acaccttatt
      361 ttttctgtct agtctagtgt agccgattca aattgatgaa gcagatccca aagggctgct
      421 tcatcaattt tttcgtaagt gtccgtacac ttactgtgct tgctcatata ttaatcgatc
      481 atatactaat cgtgtaagaa caactttaag cataatactt atattgttat accatagttt
      541 ggaaaaataa aaaattatat ttcatcaacg tttcataaaa ggtgtgtaga atgttattga
      601 aagtagctat aaaatgctat tgtgtaaaaa ataaaggagg aataatttat gaaaaaatag
      661 taccaagagg agcatgccta ttacttgcat tatgtttgag cttaagcgca gttgggtgtc
      721 aaaaaagtaa tgaaaacaat aaaataaaag aaggacaatc cataagttct gaagaggaag
      781 gcatgtcaat taatgcaaat ggcaaaaatg aaacttttaa gccatcagat tatacattgg
      841 aggcaaagaa agaatatgtt tatgaatatt tagggcttaa atttaaactc tcagacaaat
      901 ttagaaatta tatagctgat aaaaagatag cgatgttaga tgatcaaagt cctatagata
      961 aagaactaaa gtatgctatt ttgacatttg agaaaatgac agaagaacaa aagaatgcag
     1021 ttatagaaaa gatgggcgat ggatataaaa attggcaaaa tgagcttgaa agaattggga
     1081 ctattggtat atttgaaaaa aatacatcag aagaaaaaaa tctaaaatta taaaatgtga
     1141 tactcatact aaaataggag tttcaagtga tggaaaatac gattgctatt taagcacaaa
     1201 tagcggagct gaaagtaatc ttctggatga attaaaaaga actgagattc aaattataga
     1261 taaaaaagaa cgtcctaaaa atggttttgt gctatcagaa aaaactgatt tagaaaatac
     1321 agaagcattt aacaaagaat cggttaaaga tttacgtaaa ctaccaacaa aggacataaa
     1381 tggcaaggat tttacaagta aagattttga gaagtatgat cttactatgg taaatgtatt
     1441 tgcaacttgg tgtacagctt gtgtaaagga aattcctgat ttggttgagg ttcagaatga
     1501 aatgaaaagc aagggtgtaa atatcgttgg agttgttaca gatcctgttg atgataacgg
     1561 tgaaaacaag gaagcaattg aaaagtcaaa gttaatacat gaaaagacaa aggcttcata
     1621 tcctttctta atgccag
//
LOCUS       DADVXE010000168         1516 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.175, whole genome shotgun sequence.
ACCESSION   DADVXE010000168 DADVXE010000000
VERSION     DADVXE010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.175"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            49..>1516
                     /locus_tag="KB913_002934"
     CDS             49..>1516
                     /locus_tag="KB913_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBB6821210.1"
                     /translation="MDPTVFEAEEHIQKVIHKMFRPDNAYTKFDFRNGRPTKSAILTT
                     SSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTMEDPDFPRIAITYSLEENSRD
                     SSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNRLARKRAEFKQFGKQIDLVIV
                     VDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTYPEKTKGLIVTFRKPATMEKN
                     VEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKEVSSMESIDEHTPLEIRIEYV
                     KAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEEQIGVYETVKGSLMEEEPEKE
                     GEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSDAREEIEKALAKLNKTEGVKE
                     VYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHAFSNEWFVSEKELHASNLQYM
                     PGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMKR"
BASE COUNT          551 a          255 c          305 g          405 t
ORIGIN      
        1 atcaatcgta tgatcgatca aatggagtct gtcaaaaaag aaagttattt ggaccctact
       61 gtttttgaag cagaggaaca tatccaaaaa gtcattcata aaatgttccg tccagacaat
      121 gcctatacaa aatttgattt tcgaaatggc cgtccaacga agtctgcgat cttaaccacg
      181 agttccattg atatggccaa aaagtattat cgggccatca aagagatgac gaaagaatct
      241 gattggttaa taaaagagtt tcccaatcag cctatccgtg aaggacgaac gatggaggat
      301 cctgatttcc cacgaatcgc tattacctat tcattagaag aaaatagccg agattcaagt
      361 gcccaacaag aagaaatgca aaaaattatt gaggaatata atcagtatta tgatactgcc
      421 tggtcactag cagacattga gcgttataac ggagacatca ataatcgttt ggcacgaaaa
      481 agagcggaat tcaaacaatt tgggaaacaa atcgatttag taatcgtagt ggatcgtcta
      541 ttgacaggtt ttgacgcccc tacgattcaa accctatttg tggatcgtaa tctagagtat
      601 gcaggattga tccaagcctt ttcacgtacg aaccgtacgt atcctgaaaa aacaaaagga
      661 ctaattgtta ctttccgaaa gccagcgaca atggagaaga atgtcgagga tgcgacaaaa
      721 ctgtattcag aagctaaaga agaatcgggt ttgatttatc caagttacca agaatccaaa
      781 aaaagattca agcaagcata tggtaagtta aaagaggttt catccatgga atccattgat
      841 gaacatacgc cacttgaaat ccgtatcgag tacgtcaaag catttcaaga attgaatcgt
      901 gcgtatgaat cgttagtgac ttatgatgat tacaatgatg acatggtgca atcttcaact
      961 ttgaacaatc aaattcaact tttggaagaa caaattggcg tgtacgagac cgtgaagggt
     1021 tcattgatgg aggaagaacc agaaaaagag ggagaagatt tttcaacgat cgaattttat
     1081 agtgaaaata ccactaagtt gtatgatatt gattctactt atattgatca attactagga
     1141 acttatgctg cgaatagttc agatgcacga gaagaaattg aaaaagcttt ggctaaattg
     1201 aataaaacag aaggagtcaa agaagtttac cgacaaattt taaatgcatt tgatgtgggg
     1261 actttagata gtaatgaaga tatctttgtc attaaacgtc gctattttac acaagcaagt
     1321 gataatttga ttcatgcctt ttccaatgag tggtttgttt ctgagaaaga attacatgct
     1381 tctaatctgc aatatatgcc aggtgaagat ccaattccta atatgaaagc aattatcaac
     1441 agtaaggatt acgaaggata taaagccaaa catccagaag cgaaaccatt taaataccca
     1501 caagaaatga agcgag
//
LOCUS       DADVXE010000169         1509 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.176, whole genome shotgun sequence.
ACCESSION   DADVXE010000169 DADVXE010000000
VERSION     DADVXE010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.176"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..626)
                     /locus_tag="KB913_002935"
     CDS             complement(<1..626)
                     /locus_tag="KB913_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6821211.1"
                     /translation="MDNHTRKLLVLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLRFPR"
     gene            914..>1509
                     /locus_tag="KB913_002936"
     CDS             914..>1509
                     /locus_tag="KB913_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6821212.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKK"
BASE COUNT          530 a          216 c          286 g          477 t
ORIGIN      
        1 tttctaggaa agcgcaggaa gtattgagtt agtttgtaaa gtctgcgatc ttcaaggatc
       61 gtaaatagct gatgggttgt cccatcaaca caaataaaac tcatggaacc agaaacagac
      121 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
      181 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      241 ttagcgatta gtttacgtga ttgattttcg tacagttcta tgagaatcgc ctgcttcagt
      301 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtctgccca
      361 caatcatagc atagaaaacg ggtacgtttt aattctaaaa tagtcaactt ttctttgact
      421 ttcaatatct gagtacgtgt cgtataggaa ccgttgcgga taatacgaat cgatccacag
      481 tgttcacaat gggaaggtga gtcatccaat ctccctttaa taaactgcgc ttgaacgcct
      541 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatacg
      601 agtaattttc tagtatgatt atccatagag cgactccttt ggtagggtga tgttttggtc
      661 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
      721 gaaaatcgcc ttcgattttc caacaacaca aaatattata gaacccttta ttctaaagga
      781 tttcaaggtg tctgtttgca tttattagaa aaaagaaaaa gtattggcaa cagaaggtgt
      841 caccaacact agatattata gagccataat atgctgtata atatctagtg tataggctta
      901 agtggaggta tatatgaaaa tattaactgt tgaagatgat aatatgataa gagagggaat
      961 aagtgaatat ctttcagaat ttggatatac tgttattcaa gctaaagatg gaagagaagc
     1021 cttgtcaaaa tttaatagcg atataaattt ggttatctta gacattcaga taccttttat
     1081 aaatggttta gaagtgttga aagaaattag aaagaaaagc aatttaccaa ttctaatctt
     1141 gactgcattt agtgatgaag aatataaaat tgatgcattt actaatttag tagacggata
     1201 tgtagaaaag ccattttcat tgccggtctt aaaagctaga atagattctt taattaagaa
     1261 gaattatgga catttagaga agtttgaata taaggatcta tcggttaatt ttaatagcta
     1321 tacagctaaa ataaatggtg aagaaataga tgtaaatgca aaagaactag aagtattaaa
     1381 atgtttattg gataataatg gacaagtgtt aacaagaatg caaattattg attatgtatg
     1441 gaaagatagc gaagaaactc cttatgatcg agtaatagat gtatatataa aagaacttag
     1501 aaaaaaatt
//
LOCUS       DADVXE010000170         1459 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.177, whole genome shotgun sequence.
ACCESSION   DADVXE010000170 DADVXE010000000
VERSION     DADVXE010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.177"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            314..1354
                     /locus_tag="KB913_002937"
     CDS             314..1354
                     /locus_tag="KB913_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBB6821213.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
BASE COUNT          574 a          194 c          226 g          465 t
ORIGIN      
        1 tatgttttat atgcataagg tagttcttaa tttatttttt gttttgacac tggtagtact
       61 taattatctt taattttaaa actaaatttt attcatacgt ttttctggta gtatttaatt
      121 ataaataata tttatttaaa gtagttctta atgactttaa aggtagtaca taattcattt
      181 tatttctgat tttaggtagt atttaattaa aaaacagttt taatgcgttt gcatttttta
      241 tttatctttg ctattttcga aaagagtagg taattttaca taaataaaac aacgtgaaag
      301 tagaggatct acaatgactg attttaaatt ttttaaggcg gatagagttt acaacgaatt
      361 attttatcaa tttccaaaag tctttattgt ttctgacgaa tacaaaaaaa tgaaagattc
      421 aactaagatt gcctatatgc ttttaaaagc aagattagag atcgcaatca gcaaacggca
      481 aatcgatgaa gaaggtaatg tttattttac ttatacgaca aatgaactat gtagagtatt
      541 aaactgccaa aaacaaaaag cgatagcaat caaaaaagag ttggaatcct ttggtttatt
      601 attacaaaag cagatgggat ttaacaaaca gttagggaaa aataatccta atagactata
      661 tctagcagaa ttaaaagtct cagaaaatga tatctactta ctcgaaaaat ttgatagaga
      721 gaatagggaa aacgttgata aatcagaggg tatgaaaatc atacccaccc tcgacgaaaa
      781 atcagacgct gaatcccttg gggctcaaga gggtatgaaa atcataccgt gccaaaacgt
      841 tgataaatca gagggtatga aaatcatacc agaacttaat aataatatat tagacactaa
      901 tagacacaat atagacactg aaaaagaccg cctacaagat caattgttgt tagacaattt
      961 tgagacaatt atgacaaacg acagcattgc tacgtttgtc cctgaacgag tattaaattt
     1021 gataaaaaca ttttcttcaa gttacagtga agctcaaaaa accgtccaga ctattcataa
     1081 tgcaaagaaa aaagctgaaa tagaaagtga tatttcgata gtttttgaag aactcgatag
     1141 ttattatgtc aatgcagaac aagaattata cacgacactg ttaaaagcct atcaaaaatt
     1201 aaaaaccgaa aaagtcgaaa atatccagaa cctgattttt gtctatgtaa aaaattggtt
     1261 tatcgaaaaa ccaatagctg ctaaagtatc aagtgaaaaa cgtttgaatt atgcaagctc
     1321 cccaagcact attacgaaag actggttaga gtgaaacttt actgacaaag tgattgttgc
     1381 ttcatggagt aacattaaaa ttaaaaattt tttattattc taattatatt acgaatatta
     1441 caaaataata gctatttta
//
LOCUS       DADVXE010000171         1364 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.178, whole genome shotgun sequence.
ACCESSION   DADVXE010000171 DADVXE010000000
VERSION     DADVXE010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.178"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            80..>1364
                     /locus_tag="KB913_002938"
     CDS             80..>1364
                     /locus_tag="KB913_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBB6821214.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLI"
BASE COUNT          465 a          263 c          257 g          379 t
ORIGIN      
        1 tttaggtatt aaaaaacata tcgttctcta gtatgattaa atcaccacaa aataaacaac
       61 tgagaggacg atacgctata tgaatgattc tatcaaaaaa atgctgagaa taacagagaa
      121 agatttgatg attacagagg tctcttacga gacccttcag aagaaaaaga cgttggtcgt
      181 cgatgctgtt ctctcgccta ctcctcgtgc ttgtagaagt tgtggttcta ctgtggtaga
      241 tggaaacggg aaagcaatta tagtgaaaaa tggaaaaaag gaaacgattg tccgttttga
      301 acaatacaat catatgcctt tggttatgcg cctaaaaaag caacgctata cctgtaaaaa
      361 ctgtcgcacc cattggacgg ctcaaagtta ttttgtccaa cccagacatt caatcgcaaa
      421 tcatgttaga tataaaattg cttctttact gactgaaaaa gtatctttat cttttattgc
      481 gaaaagctgt caggtatctt tgaccaccgt tattcgtaca ttgaaagagt ttaaaagcta
      541 tttaccaaag caatctaaga agatcctccc cagagtattg atggttgacg aatttcgttc
      601 gcatgcttcc atagaagata agatgagctt tatttgcgcg gatggcgaaa caggaaaatt
      661 aatagatgtt ttgcctacgc gtaaattacc tcgattaaca agctatttct taggttgtac
      721 caatccagaa gaagtagaat tcttggtgac agacatgaac gccgcctact tccagctcac
      781 caaacgtgtt ctgccaaatg cgaaagtcgt gattgatcgg tttcatattg tcaaacacat
      841 gaatcaagcg ttcaatgagt tgcgtatccg tgaaatgaat gaacttcgta aagccggaca
      901 gaaaagccag gcagaaaaac tgaaaaagaa ctggcgcttt ttgctaaaaa atcgtgcaaa
      961 catcaaccat tatgaataca aaacatggaa aagtttccga gcaccaaaat acccatttct
     1021 tactgaagca atgatgattg atcgattgct tgagttttct ccgcccctaa aggaggcgta
     1081 tccctttttt catgaattag ttgaagcctt tcgagacaaa gaccctgact tatttttctc
     1141 cttattggca gaacttcccg aaacgttaga tgacagcttt cgggaaaagc ttcaaaacct
     1201 tctgacctat gaagaaggca tcaccaacgc aatgatctat ccttattcca atggaaaaat
     1261 agaagcgaag aatacccaca taaagacaat gaaacgagta tcctacggat ttaaatcatt
     1321 tgagaacatg agaattagaa tctttttgat caatcaatta atca
//
LOCUS       DADVXE010000172         1355 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.179, whole genome shotgun sequence.
ACCESSION   DADVXE010000172 DADVXE010000000
VERSION     DADVXE010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.179"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..1355
                     /locus_tag="KB913_002939"
     rRNA            <1..1355
                     /locus_tag="KB913_002939"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DADVXE010000173         1315 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.180, whole genome shotgun sequence.
ACCESSION   DADVXE010000173 DADVXE010000000
VERSION     DADVXE010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.180"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            25..1293
                     /locus_tag="KB913_002940"
     CDS             25..1293
                     /locus_tag="KB913_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBB6821215.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVRKGILFLPIVKRMKEKNKV"
BASE COUNT          324 a          236 c          318 g          437 t
ORIGIN      
        1 ttttttattg aggaggaatt ttttatggaa aaacaattac cgagtccagt acgcatttta
       61 gtgtacatgc tgaagtggct ggtgatcaca gcgattctcg gtatattcat ggggagctta
      121 tctgcttttt tcttaaatag cctgacagtt gtgacagata tccgactatc acatccttgg
      181 ctcctttatc tactaccagt tagtggtgcg ctttttgctt atctctatgc gtatcacggc
      241 ggtctttcta gtcgtggaaa caacttagtg atcgatcaag gaaatggtgg agaagaaaaa
      301 atcccgttgc gacttattcc acttacactg tttggaacca taactaccca tttatttgga
      361 ggatctgttg gccgtgaagg aacagcagtc caaatggggg gagcgttagc agataataca
      421 gcacgtttgt tccgattgga taaatcagaa cgggaaatct tgattatcag tggaatcagt
      481 gcgggtttta gttctgtatt tggcacacct ttagctggaa cattatttgg attagaagtg
      541 ttggcaatcg ggaaagtccg aacagaagcg atcttcccta gcttctttgc tgcactgttt
      601 gcaaatttta tgacagaaag ctatggtgtt tctcatctac attaccaaat gggtgtgatt
      661 cctgaatgga gtatgttgct gttcttcaaa gtttttgttg ctgggattgc ttttggtttg
      721 attggttggg tattcagccg ttcgatcgtc tttttaaaag cgcgatatgc acaatggatt
      781 cctcatcctg tttggcgaaa tacgataggt ggggctgtag ttgtagccgc agcattgatt
      841 ttgcaaacac aacgttatct cggattgagt cttccattac tgcaggaatc atttaatgga
      901 caggcacatg tctatgattt tattgggaag ttattcttca cagttttgtc tttaggcgcg
      961 ggatatcaag ggggagaagt gacaccattg tttgaaattg gtgcaacgct tggtgcagca
     1021 ctagcgcctt tgctccatgt ttctgttcct tttcttgcag gattgggctt tatcggagta
     1081 ttttctggtg cgacaaatac accgattgcc tgctttgtga tggggatcga attgttcggt
     1141 tcacaagcgg cagtatactt ctttatgatc tgcttgatca gctttatgtg ttcaggcaac
     1201 agcggtattt attctgctca gcaagtagcg gtcagaaaag ggatactctt tttgccaata
     1261 gttaagagaa tgaaagaaaa aaacaaggtg tgacatatgt tttgtcacac cttgt
//
LOCUS       DADVXE010000174         1310 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.181, whole genome shotgun sequence.
ACCESSION   DADVXE010000174 DADVXE010000000
VERSION     DADVXE010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.181"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(49..348)
                     /locus_tag="KB913_002941"
     CDS             complement(49..348)
                     /locus_tag="KB913_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821216.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(354..584)
                     /locus_tag="KB913_002942"
     CDS             complement(354..584)
                     /locus_tag="KB913_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821217.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(834..1034)
                     /locus_tag="KB913_002943"
     CDS             complement(834..1034)
                     /locus_tag="KB913_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6821218.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          451 a          216 c          200 g          443 t
ORIGIN      
        1 agtatggtga taaaatccgt tccgggctac ctttttaggt agcctacttt aatctttgta
       61 tctttctgga tcaacgaaag tatactttat atagtcataa cgccgatgat cgcttcgagc
      121 gtctagcaca tcagtcacga tatcaaacaa aaaatatacg tctttcttca ttctagtttt
      181 cgcagcaggg attttaaagt agttcttatt agaatagtag agattaatta ataagctatc
      241 ttcgattgct aaaaagaaaa cttctgaatc ccacacctta taaaaatctt tgacaaatct
      301 attcgaagga tcaaatttaa accataattg cgtctcatta aaaagcataa ccattactcc
      361 gatctatttt taaacttagt ctctacctct aatatatatc gagtttttat tttgccttca
      421 gagaatactg tttctttttt tgcagttaca ggttgtttat tttcggaaaa agctaatata
      481 gctaaaattg aaacatccat ctggaatttg tctttttcgt tgctttgctc ataaaaatct
      541 gcatattcat cactaatatt ttttctaata aattcttcca tcataaagat cacctcgaaa
      601 agagtatacg aacaaacgtt ctttttgtaa aggtggaatt tattatacta aataaatagg
      661 tgaacaagta cttgtgccaa attatgtgcc aaaaaaaatc gaatttaata aaacacaaac
      721 aaaaagaaat cctattatga taacatttct tataataaca aacacaacag aagacgtgta
      781 atagttagtc aggaacgtac aaataacccc tgtatccttt gcggtacagg gggttatttt
      841 gtataagtag acattgtagt ttctaaactg ctatgtccta aacgtttcga tacgctaagt
      901 atatttactc cttgataaag taaaatagat gcatgcgtat gtcttagtcc atcaataaac
      961 agtcgaagag aaaataggga aaaattgatt actaaagaaa aacttactag gtcgacggtg
     1021 tagttgattt tcatacttca atagattcga attaaacgat ttcgattggc ttataccagt
     1081 cctatccaac gaaagatata tcgttcttaa ctctagcggt ataacttgaa gctttacgta
     1141 aagccaatgg gaatgaactg gagatgactt tttattattt ttagtaatag ctgatgggtt
     1201 aatacttaca actttccttt tcaaagtacc atataaaaaa acggtggggt tgtttagcga
     1261 aataaaggat ctaagccaat agcttagatc ctttattcta tgctttatat
//
LOCUS       DADVXE010000175         1284 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.182, whole genome shotgun sequence.
ACCESSION   DADVXE010000175 DADVXE010000000
VERSION     DADVXE010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.182"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(101..1024)
                     /locus_tag="KB913_002944"
     CDS             complement(101..1024)
                     /locus_tag="KB913_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821219.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGTLGWTETYYEKIYKEIIEQYFPK"
BASE COUNT          417 a          230 c          130 g          507 t
ORIGIN      
        1 ctacaaaaat atatcccact caaaatcttg acaaaagaaa aaagttgtga ttttggaaat
       61 cacaactttt ttcttttacg ataaatcaat ccttattaaa ttatttagga aaatattgtt
      121 caattatttc tttatatatt ttctcatagt atgtttctgt ccatcctaat gttcctataa
      181 aatcaagtcc tctacatttt aaaggttcac ttaaactatt aatatagtta ataatgttgt
      241 ctatcctttt ctctttatct tcaccttcaa tctggggagc atatagtcca atttcctccc
      301 aataatatga atctctttca attcccatga tggtagcttt ggctaatttc aaatcaaata
      361 acgattttag aattcttagt gtctcaataa agtcttctct cttcaactct ttaatccatt
      421 gtgaattttc tggattatct aaaatttcaa gttcatcttc attataagta tatttcaaat
      481 ttgacttgct taactcatag ataaatgaag tttcttgact cataattctt ttaagtactt
      541 gactataagt ttcgtttgac tttgcccatt tcgctaattc taccactgta ttcactaata
      601 aatcgaaata atgatgttct cgttcaatag tctcagcatt ttgaaaatga aaatcacctt
      661 tataaactcc attcttttcc actgttttat taatattttt taaaaaccag aatgagtttg
      721 caaatttagt cgtacttttt cgattaacta agttaataac tcttccatgt aataataaga
      781 caaaaataca taaattttta gcttccttat tattagatac taattgatca atcataggga
      841 gccatttttt gattttcact aattgattgc tcataaatct ttcactggac ttttgttcaa
      901 tcttaaattg caaaacttct aactcataat tcccatcttc tgatttattt ttgggaacaa
      961 ctatcaaact tttataaagt ttatccacat caaaatttat cttttttgca taatttgtag
     1021 ccattaatac atctccttat tcataataaa tttcatatga cgctcctctc aaaatttacc
     1081 ggtagactag aaaaaagaat aaaagatacg tcaattcaca ctttattctt aaaaaaaaac
     1141 tggtctctct accggtaata tcgattgagt ccgcctttat cgactttatc ctttttttat
     1201 attaaatttt ttcaccggta gacagggaga gaaagaataa actaaaaagc ccttaattct
     1261 taatgttttc acctccttac cgtt
//
LOCUS       DADVXE010000176         1273 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.183, whole genome shotgun sequence.
ACCESSION   DADVXE010000176 DADVXE010000000
VERSION     DADVXE010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1273
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.183"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(243..392)
                     /locus_tag="KB913_002945"
     CDS             complement(243..392)
                     /locus_tag="KB913_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821220.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            854..1066
                     /locus_tag="KB913_002946"
     CDS             854..1066
                     /locus_tag="KB913_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821221.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
BASE COUNT          477 a          189 c          209 g          398 t
ORIGIN      
        1 tatattaaat attatacaga taataacgga atattatcat cgaaacagct aacaaaattg
       61 tcataaaaaa cgagatggtt gatattagaa cttgtgtttt tgtttaggtc tagagataaa
      121 gagagacaat ttccaaatat atgtaatgaa tacaaaaaga cgtttgtcgc ggattaccgt
      181 tacaaacgtc ttttattgat tttccgagat ctcatcagtc gccatttgga atggttcact
      241 ccttatctag attcgtttaa tgctcggact gcttgttcga ttgtaatacc aaacgcaacg
      301 ttattttcgt tttgtgcatc aatcgccata aaacggttag aagttgtatc aaaagctacg
      361 cggtattgca tatttgtttt tgtaaacgtc ataaaattca tctcctttgt aatgtaattt
      421 agttcttgaa agtttccttt aaactttcga acttatacca agtttagcat cgtacgtttt
      481 ttgatgcaat taaaaagcat ttatcatttt ccttatttat tttttcttaa atggtttagc
      541 tattttcttt taatccgata agtagcccaa tcatcaaggt tacaaatact attgcttgaa
      601 tataaatcat atgctcacct ctttataaat aacttagcaa tataaagaaa aaaacgcacg
      661 aacaacatag gaatataaac aaacgttttt gtcacaacgt ctaagatcgt gttaaaaaat
      721 agttatctaa aaagcagaaa gatactcaaa ataaaaaata aaaaaatgga taaaaacgtt
      781 ttcaaataca aggtaatttg ttattataaa ataaagaaaa aacaaaataa aaataaagaa
      841 aagagggaat gaaatggtaa aagcagaagt aggaagatct tatatatgca aaccgatcgg
      901 agtatctcat gaactaatcg gctgtattga acgtacatat atcaacacgg ctgtcgtgta
      961 tgttgaaagt tatgaccaac gagactatca acttatcaat gaaagcaagt atcgcatgct
     1021 cgtaaaattc tgtgatatta gcgcacctgc tgaattggtt tcttaaacag tatttttgag
     1081 aattcgcaag aactccctta taatataaat aaagacagaa gggagcgaga agatatgcca
     1141 aaaagaaaaa gttcagggaa aatgggaatt attcttgcag tgatctctgc aattcctgct
     1201 attttagcta ttgttcgtgc gatgaaggaa tcaagagaaa gttaagcaca cattatgagc
     1261 gtcaaacaaa aaa
//
LOCUS       DADVXE010000177         1255 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.184, whole genome shotgun sequence.
ACCESSION   DADVXE010000177 DADVXE010000000
VERSION     DADVXE010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.184"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            36..908
                     /locus_tag="KB913_002947"
     CDS             36..908
                     /locus_tag="KB913_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6821222.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT          377 a          230 c          303 g          345 t
ORIGIN      
        1 agtgatttca ttctaaaata aagggagaaa tgtctatgct atacggtgca attgaagcag
       61 gcggcacaaa atttgtgtgt gccattggcg atgaagaaat gacgatcaag gaaagagtga
      121 gctttccgac aacgacacct gaggaaacaa tgcctttagt cattgacttc ttcaaacaat
      181 accaagcaga tttagcaggg attgggattg gctcatttgg gcctatcgat atccatcgcg
      241 attccgccac ttatgggtac attacctcga ccccgaaatt ggcatggcaa aattttgatt
      301 tcatcggtac catgaaaaaa gaatttccga tcccgatttc ttggacaaca gatgtcaatg
      361 cggctgccta tggtgagtat gtcttcggca gtggcaaagg attgagcagt gtcgtttact
      421 atacgatcgg tacgggtgtt ggcggcggtg ccttacaaga agggcgcttt atcgaagggt
      481 ttagtcatcc agaaatgggg catatgctcg tcgtccctca tccaaaagat gactttgctg
      541 gcagctgtcc atttcatggc aactgtttag aagggatggc cgctggaccc gccatcgaaa
      601 accgcttagg gaaaaaagga caagaggttg cagaagatga tccttattgg gaaatcgaag
      661 cctcctatat tgctcaatgt gcctacaata caaccttgat gttttctcca gatgtgatca
      721 tttttggcgg tggtgtgatg aaacaacgcc atatgctgca aaacgtccac gacgcatttg
      781 caaaattggt caatgggtat gtcgaaacac ctgagttaag caaatatatc gtgaccccag
      841 cattagaaga caacgctgga acgctcggtt gtttggcatt ggctcgagaa gcggtcttac
      901 attcataaac gaaaaaaggc tcttcgacat ttagtgttgg tagagaaaga tacaactgaa
      961 aatttagtca taaccagtta ggcagagtgc ttaactggtt tttgttttac ttggaagatc
     1021 aagccttgaa tgagataaat tcttgctcga aagttatgga aatttcgata gccgtaggcc
     1081 acttgtattg tgcaatagtt ttttacaaaa aaaagggggt gcggatattt ttttggacct
     1141 ttttaacaaa taggttctgt tgcaaagttt taaatctact atcagataag gtagaataat
     1201 agaaaaagat agcaggagga atgacgatga gtcattttaa aggaaagcaa tttca
//
LOCUS       DADVXE010000178         1240 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.185, whole genome shotgun sequence.
ACCESSION   DADVXE010000178 DADVXE010000000
VERSION     DADVXE010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1240
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.185"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            16..1185
                     /locus_tag="KB913_002948"
     CDS             16..1185
                     /locus_tag="KB913_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HBB6821223.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
BASE COUNT          449 a          187 c          211 g          393 t
ORIGIN      
        1 aaagaggact tccatatgaa cgattttact acagaaatta tggaaatact aatcaataaa
       61 ggtgatttgg atgatttgtt tcgtcgtcac ctagaattgg ctattaacgc tttattacaa
      121 gctgaattaa cggtatttct tgactatgaa aagtatgata gagctggatt taattcaggt
      181 aattcccgta atgggaatta ttcgcgctct tttaaaacag agtacggtga attgaattta
      241 gtaataccta gagataggaa tggagacttt tctcaacaaa ctttacctgc ttataaaaga
      301 accaatgact ctttagaaac cactattatt cagctagttc aaaaaggaat tactatgtcc
      361 gaaatctctg atctaatcga aaaaatgtat ggtcattatt acaaaccaca aactatttca
      421 aatatgagta aaattgtgtc tgaagatgtt tcggcattta aagaaagaac tttagaagct
      481 aaatactcag tcatttttat ggatgctact catattccct taaaaagaca aaccgtatca
      541 aaagaagctg tctatatagt aattggtatc aggttggatg gaactaaaga ggttctagga
      601 tttactatag ctccaactga atctgcttat gtttggaaag agattcttca agatctaaaa
      661 gaccgtggtt tagaagaggt tttgttagtc gtaacagatg gtttaagtgg tattgacgat
      721 agtattcata gtgtttatcc aaatgctcaa tttcaacaat gttgtgtcca tatatctaga
      781 aatatcgctc ataaggttcg tgttagtgat cgacaagaaa tctgtagcga tttcaaatta
      841 gtttaccaag caagttcaaa agaagaagca aataatcaaa taaggtttat gatagataaa
      901 tggaaaaagc agtatccacg agtggttaaa ttgctcatga atcctgctat attaaccttt
      961 tataatttcc ctccgtcaat cagaagaact atttattcaa ctaatttgat tgaaggtttt
     1021 aacaaacaat taaagaaata taccaaaaga aaagagcaat ttcctaatga agaatctctg
     1081 gagagatttc tagtatctca attcaacaac tataatcaaa agtttctatg ccgagttcat
     1141 aaaggtttta aagaaataca tgatacatta gaatcaatgt tttaacttga tcaacagaat
     1201 gggcttttcc atttacacaa aattattgac gctcccgaca
//
LOCUS       DADVXE010000179         1220 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.186, whole genome shotgun sequence.
ACCESSION   DADVXE010000179 DADVXE010000000
VERSION     DADVXE010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.186"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..461
                     /locus_tag="KB913_002949"
     CDS             <1..461
                     /locus_tag="KB913_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBB6821224.1"
                     /translation="LLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTTLFVSV
                     IYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGLLPKFM
                     KVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            470..697
                     /locus_tag="KB913_002950"
     CDS             470..697
                     /locus_tag="KB913_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6821225.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          377 a          196 c          204 g          443 t
ORIGIN      
        1 cattgctatt aaaatttgtc gttttaggta taagtgccgt atttattttg ttcggcgtac
       61 ttttttatac tcagatcgct acaagcgaaa aaggattcaa ttttgattgg cagaccacat
      121 tatttgtttc tgtcatttac tttgcccttc tcctagggat cgttattgct tatttcttat
      181 tgaaactatt gaaaaaaatc gaagataacc aagctttttc cactcaaagc ttaaacatac
      241 taaaaaaaat cgaacgaacc attttgttta ttggtttcgc cttttttggc ttacttccta
      301 aatttatgaa agtagcggat ttagacgatg ctccaggttt gatgttggta ggaatcgctg
      361 tcgtattcat tccttttgca gtatacacat taacaagcgt gctggaaaaa ctgcttgaac
      421 atgcgatttt acttaagaca gatcatgatt tgacagtgtg aggtgcgaca tggcaattat
      481 cgttaattta gatgtagtat tagctcaaaa aaaaatgagt gtgactgaat tgagtgagaa
      541 agtgggcatt acgatggcaa acatctctat tctaaaaaat ggaaaagcaa aagccatccg
      601 tttttccact ctcgaaaaaa tctgccaagt tttggagtgt caaccaggtg atttgttgac
      661 ctataaaaat gactcgaata ctataccaga agaataaaat aaagtagaac aaacagtaaa
      721 taaaaaataa tctgaatgat agatgtgtga gacttttaga agttatttac gtctattatt
      781 cagatttttt atttcgattg aataccgttt tatctataaa taagatatgt actgactcat
      841 acaaaggggg ccttttcttc tccatgtact atcacttttc ctgatacaac tggtttcctg
      901 ttacgttgta gttggatctg cttttagtat aatactttat tcattccacc agactgatag
      961 cagtttgagc agtctaaata atcatgtagt attacaggcc attctgtttc ataccttgaa
     1021 gtgcttaaaa cttcagctaa tggcccattg tgttaactct tactccattc ttttttagta
     1081 agctcccata tatactgtaa agccttctat atattatgtc atgttgcttt ttaacattta
     1141 ctatgtagtt ttgataaaat gatttgaata acagtgatgg acaattcttt tttattttta
     1201 acattatttt gataataatg
//
LOCUS       DADVXE010000180         1185 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.187, whole genome shotgun sequence.
ACCESSION   DADVXE010000180 DADVXE010000000
VERSION     DADVXE010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.187"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            265..957
                     /locus_tag="KB913_002951"
     CDS             265..957
                     /locus_tag="KB913_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6821226.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKINNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
BASE COUNT          522 a          136 c          171 g          356 t
ORIGIN      
        1 aattattgac acaacctatt ctggaaactt acaaataaaa gcttattctt cagccacctt
       61 cgggtggtta ttttttataa aaaaatgtaa aaaaatattg atacataaat aaattagttg
      121 tagtaaatag ttttagaatt gaatttctct atccttttta aataattttt tagacaaaaa
      181 acagaaagtg tctaaagaaa gcttgacgaa gaaaataatt tttaataact tatttaagga
      241 aattttttga aggagaagat aaaagtgaga aaaaagatta ttattaatgc tggagtaatt
      301 ataggattga tgttagtaat tttctccgga aagcaatatg ctgataatat tttattatgg
      361 ggaggggaag ataatattga aaagatcaac aacaatttaa ctatattaga cacagctcta
      421 gaaaataaag agcaaaaaat tagtatttta aattcacaat tgtcttcaaa caaccaaact
      481 cttgaacaac taagaactaa tattgaagtt tccaaacaaa aagtggcatc tttagaaaac
      541 gacaagaatc aattagtatc agagaaaact aatttagaaa atcaattgtc agcaaaagac
      601 tctgaattgc aaggaaaaca aaatgaaatt aatgcgaaaa tagacgaaat taaccaaaaa
      661 gtagctgaaa taaatcgatt aaatagcgat tggaataatc gtttacaaaa tgaaaagaac
      721 aaatttaatg aagaacaatc tactattaat agtttaaacc agcaaattaa tcaaatgttg
      781 agtgaaaaaa ataacattca aaatcaactg caagctactc agcaaaagct agaagaagaa
      841 aagtcaaaaa atagtagttt gaataattac attgaaaagc ttcaaaaagc taaaaatgat
      901 gtagaggata ccgcaaataa agcacaacaa attgtaaatg aacatacaat ccaatagata
      961 tagttttaat ttaacaaatg gtatgtttgg agataatgag atagaatata aatgtcataa
     1021 tattatacaa tctaaacacc gtttcctttt ctatttttga tgacatcagt atatagctac
     1081 tcgaaagagt agtcttttta ttattctcgc ttattattga tatgaaaatt tcgatttgac
     1141 aaaaggtacc gaataatttt gtaatatgaa ttattatcaa gaagt
//
LOCUS       DADVXE010000181         1111 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.188, whole genome shotgun sequence.
ACCESSION   DADVXE010000181 DADVXE010000000
VERSION     DADVXE010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.188"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            287..694
                     /locus_tag="KB913_002952"
     CDS             287..694
                     /locus_tag="KB913_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821227.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            708..1109
                     /locus_tag="KB913_002953"
     CDS             708..1109
                     /locus_tag="KB913_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821228.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
BASE COUNT          415 a          138 c          194 g          364 t
ORIGIN      
        1 tgaggggaag tacatatagt tgttgatata gttgctaata ttgttagcta atttgttagt
       61 aaaactgtat acgaatttag atagtaaaaa aacagtttgt tccttatata gaggcacttt
      121 tactactgat taaatgtcag atatgcttac aaatatactt ataaatatgc ttacaaaatt
      181 agctaatatt tccgttgaca aagctttgtt actattgtta aactaaattg actagcaaaa
      241 gtgaaacata aatttattaa ataaatgtaa aaattaggag aaatcaatgt cttatagagt
      301 acaattaata atttcagaag atgtagaaag tcagcaattt ggcactaatg ttattaataa
      361 agtaattaat ccagctcttt ctattaatgc gcctttaatt cctactgctt tatcattttc
      421 tgtaacagct gtggtgtctg agatagagga tacagaaaag ataaaaatag tagaaattga
      481 agttttaaac aagaatgaaa aacaaatttt ttctacgggt gaagtatcgg taagcttgcc
      541 tcctcaagtt aacgatataa actttaatat aaacgccaga aatgtcttgg ttgaagaagc
      601 aggagagcat tatgctgttg ttaaatttaa tggaactgag attggaaggc aaatctttga
      661 tatcaaggtc aacaaaccag tggaaaaaaa ttaaggagac gatacggatg cttgatatag
      721 taccatcaaa tacacatcgg agtggtagct taataaattt tgctgcgatt tttgcttgcg
      781 catcggtaat tctagcatct ccagttgttg tggatgcaag ttctactccg aaaactaaaa
      841 atgataatca acttgtaatt actacaaaaa atgagattaa cacaatttca agtaatgatg
      901 gcaaaatttt tgatgtgata aatacggttt taaaaagaaa agctgaaatc aatataaaat
      961 atgatgaaga tttaaacttg tatttctttg ttatcaaaac aacatctgaa ttgttttcct
     1021 cagattacga tgttttggat actctcgata atgtattatc tgactataaa tatatgggga
     1081 aatctgtagt agcaactttg ggggaataaa a
//
LOCUS       DADVXE010000182         1108 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.189, whole genome shotgun sequence.
ACCESSION   DADVXE010000182 DADVXE010000000
VERSION     DADVXE010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1108
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.189"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(23..553)
                     /locus_tag="KB913_002954"
     CDS             complement(23..553)
                     /locus_tag="KB913_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBB6821229.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(652..1002)
                     /locus_tag="KB913_002955"
     CDS             complement(652..1002)
                     /locus_tag="KB913_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBB6821230.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
BASE COUNT          407 a          204 c          174 g          323 t
ORIGIN      
        1 ctattttaat aactaaaaat gattaacgta tagtcatttt tcttattctg atgaaattga
       61 taatctcctg gatgcccatg aaaatcaaaa taaagccgaa tatttggaat agaagcatca
      121 aacttttgaa tggattgaac aataagacga atccgccaat caacaacaga atactactat
      181 aaacactcca acttttagct tttgtattca tgctgaagaa caactggaac aagctgttga
      241 tgataacagc taatccaaga agaatcggca ggatagaaac gattgcaggt gcaaaagcat
      301 agacgatcag agctaagatc aggaaaaaaa gaccactgaa cagaccgata ctccaagaac
      361 ctgttttcct tttaaaacgg taagcctcaa aaagattcaa caacccaagc aaaacaagat
      421 aggcggtgat cagataaccg ataaaatgaa aaacagcaga agggtttagc acaatcgcaa
      481 tcccagaaat aatataaaca gcagctctta ataaggcgta tttttgaata ttttgtttaa
      541 tcgtctcaaa catataagaa aacctccttt gacttatttt aacgtgaact agtcatttta
      601 ccaaattaaa tgttacaaaa tgagcgaagg agaagaatat ctctggaaaa atcaacttct
      661 gaggatcttt tccatttttt tgccttttgc tagctcatcg atcattttat ctaaataacg
      721 aatttctttc atcaagttat cctcgatgtc ttctactcgt acaccacaaa caacacctgt
      781 aatcaaggaa cgtgaaggat tggggacagg ggcttccgca aaaaattgtt cgaaagtcac
      841 ttgtttttgt agttgatatt ctagttctgt ttgggaataa cccgtcagcc aacaaatgat
      901 ttcatctact tcctctttta tacgatcttt tctctccgct tttgctacat acataggata
      961 aacgcttgca aaacttgtcg taaaaatacg attttgcgcc ataatcagtc acctttcttt
     1021 ttttcaaatt atttactact tatagtatat aagaaaaaga gaagaaaaag cgattattca
     1081 aaaaaacaaa aaggattgtg acaaaatt
//
LOCUS       DADVXE010000183         1075 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.190, whole genome shotgun sequence.
ACCESSION   DADVXE010000183 DADVXE010000000
VERSION     DADVXE010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.190"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(60..278)
                     /locus_tag="KB913_002956"
                     /pseudo
     CDS             complement(60..278)
                     /locus_tag="KB913_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(544..738)
                     /locus_tag="KB913_002957"
     CDS             complement(544..738)
                     /locus_tag="KB913_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821231.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(838..924)
                     /locus_tag="KB913_002958"
                     /pseudo
     CDS             complement(838..924)
                     /locus_tag="KB913_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          372 a          185 c          156 g          362 t
ORIGIN      
        1 ggtattttta ttatatatag atttaacata tgtcggtcgg ttgattgata tagctaaagt
       61 tataactcaa ccgaagccga ttcatctaca cgaataaagt tgcgagtgtt ctcggctaat
      121 tcataaaaat tgttatgtgt tccatatagc aatactggaa taactttatt ttcttgaatc
      181 tcataagcaa ctctatacac ggtgaccgca tacttaaatc cattagacca attacctgat
      241 aaacctccag ttttttgctc ttacttaaat ggatcaatgg caatttcatc acaaacctat
      301 agaggatgag tgacttctgc ctaattacgt taaaaaatat tgaaagtaac tctatgtagc
      361 aaaaaatatc tagaatttca tttcctcaaa actgatcgat attgtatcta aaaatatata
      421 ctacctaaaa taggtagtat atattaaaat atgtgctttt gttagaaaaa tcaatacata
      481 aattatcata tctgtatatg tcatttaggt atttcagtta tgttataata gttttgctgt
      541 ctgctacccc ggcctaatct ggcaagggga ggaggagata taatgaaata cctttttgat
      601 tttgtttttg caatcaagcc acttgcagat gtagtgtgca gttacctctg caaatggctt
      661 gattgcaaaa ttgccaaaaa agacagtaag cctacccgtt aattctataa tatagaaacg
      721 taaaaaaaac cccatcagcc tgcacgctga tggggtttgg tgatataatg aaatacctct
      781 ttgttactca taattatacc ataattagtc acgaatgcaa ccaatagaaa aaactactta
      841 gaacggtaga tcatcgctaa taacaatgca ttgtccacca aatggatttt gtgaagcatt
      901 aaatacattg ttattaattg tcgctgcttt taactaggcc tctccccttc tattataaaa
      961 gaagatatat atcatttctt aattacctac taccttaaac caaaatttaa gtactaccta
     1021 atttaagtag tacttaaaca atctaaaaaa tagttatccc aattgttatg ctttt
//
LOCUS       DADVXE010000184         1069 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.191, whole genome shotgun sequence.
ACCESSION   DADVXE010000184 DADVXE010000000
VERSION     DADVXE010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.191"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..969
                     /locus_tag="KB913_002959"
     CDS             <1..969
                     /locus_tag="KB913_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6821232.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          368 a          185 c          214 g          302 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
      901 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
      961 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
     1021 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccat
//
LOCUS       DADVXE010000185         1059 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.192, whole genome shotgun sequence.
ACCESSION   DADVXE010000185 DADVXE010000000
VERSION     DADVXE010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.192"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(37..993)
                     /locus_tag="KB913_002960"
     CDS             complement(37..993)
                     /locus_tag="KB913_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821233.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgt
//
LOCUS       DADVXE010000186         1059 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.193, whole genome shotgun sequence.
ACCESSION   DADVXE010000186 DADVXE010000000
VERSION     DADVXE010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.193"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(170..526)
                     /locus_tag="KB913_002961"
     CDS             complement(170..526)
                     /locus_tag="KB913_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBB6821234.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(540..950)
                     /gene="spx"
                     /locus_tag="KB913_002962"
     CDS             complement(540..950)
                     /gene="spx"
                     /locus_tag="KB913_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBB6821235.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
BASE COUNT          335 a          203 c          156 g          365 t
ORIGIN      
        1 ttttaactct atatccccac ctagatttga attttgacca cataaattga gcatgtctct
       61 atagtagaaa aataaagtca aaaaaagaac acataacacg cttgatgcta agtgttcgac
      121 tgttacaact gtatgaaatg ctcagtgact tgattaaaac agttaaagtc tatttattta
      181 agataagctg ttccatcaac tgctcattgt atccaataaa tagaacttca tcgataataa
      241 tcaaaggacg tctgaggaga ttggtatgtt gtgtgcataa aaaaatcagt tgtttttttc
      301 ctacacagga aaggtcaatc gcaatgttgt gaaaagcctc agaccaagtc gcaaatagct
      361 gttctgcttg cacttcttca aaactgcata attcttctgc ttcttctgta cttaaatcgc
      421 gttcttctaa gtcaacaaat tgataaggca attgatggtg ttctaaccat tgtttcgcct
      481 tcagacttgt tacacagtgc gctgatccat agactttcac ttccacgaag gctccctccc
      541 tatgaattta agatgttatt gttttgtaaa tagatcagat ttctggcaac acatcgaatt
      601 tcacgaggga caaatgaccg gatctcatct tcattaaatc cgattagtat tcttttttca
      661 tcaatcaaaa taggtcgtct caataatgaa ggatattctt tgaataagac gatcatttgc
      721 tttaaagtta attcgttaaa atctatgccc agcttttcgt aaattttcga ccgagtggaa
      781 ataatatctt gaactcctcc ttcagtcgct gccaagatct ttttgatctc actttctgtt
      841 aacggttcgg caaaaatatt cttctcttca aattcaagtt gattcgcttg caaccatgct
      901 cttgcttttc tacaggaagt acagctaggc gaagtatata cttttatcat tttctcactc
      961 ctttttaatt ataatccaat tctacagtaa tttcttttaa aataccaatt attagctaat
     1021 aaaatataaa aaaaatcaaa ataactgatt atttacgtt
//
LOCUS       DADVXE010000187         1045 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.194, whole genome shotgun sequence.
ACCESSION   DADVXE010000187 DADVXE010000000
VERSION     DADVXE010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.194"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="KB913_002963"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="KB913_002963"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBB6821236.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          376 a          132 c          182 g          355 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaac
//
LOCUS       DADVXE010000188         1044 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.195, whole genome shotgun sequence.
ACCESSION   DADVXE010000188 DADVXE010000000
VERSION     DADVXE010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.195"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            215..>1044
                     /locus_tag="KB913_002964"
     CDS             215..>1044
                     /locus_tag="KB913_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBB6821237.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     "
BASE COUNT          371 a          150 c          178 g          345 t
ORIGIN      
        1 tagcaaagaa agtttaataa gagtttggac ctagcaaaca atattaatga ggtcattaaa
       61 tcttattatc tttagtgata taacgaaata tctacacaga caaaatgata gcgtaaaata
      121 ttttgtgtaa atagatattt agggtagaaa aaaagaaagt ccattctgta aaattaaagt
      181 taccacaacc gaaattttat aggaggactt tctcatgccc aattttacta cagaaattat
      241 ggaaacacta atcaataaag gtgatttaga tgaattattt cgatgtcatt tagaattagc
      301 tgttaattca ttattgcagg ctgaattaac agcttttctt gattatgaaa aatatgatcg
      361 tgctgggttc aattcaggta attcccgtaa tgggaattat tcacgttcat tcagaacaga
      421 gtatggagaa ttaaatttgg taattcctag agatagaaat ggtaagtttt ctcaacaaac
      481 tttacctgct tataaaagaa ccaatgactc tttagaaacc actattattc agctatttca
      541 aaaaggaatt actatgtctg aaatctctga attgattgaa aaaatgtacg ggcatcacta
      601 tacgccacaa accatttcaa atatgactaa aatagtttct gaagatatta ttgcctttaa
      661 agaaaggtcc ttagaatcca gatactctgt catttttatg gatgctactc acattccttt
      721 aaaaagacaa actgtttcaa aagaagcagt ttatattgta attggcattc gattagatgg
      781 aaccaaagag gttcttgggt ttagtcttgc tccaactgaa tctgcttatg tttggaaaga
      841 gattcttcaa gacctaaaag accgtggttt aaaagaggtt ttattagtcg taactgatgg
      901 tttaagtggc attaacgata gtattcatag tgtttatcca aatgctcaat ttcaacaatg
      961 ttgtgtccat atatctagaa atatcgctca taaggttcgt gttagtgatc gacaagaaat
     1021 ctgtagcgat ttcaaattag ttta
//
LOCUS       DADVXE010000189         1035 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.196, whole genome shotgun sequence.
ACCESSION   DADVXE010000189 DADVXE010000000
VERSION     DADVXE010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.196"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..>1035)
                     /locus_tag="KB913_002965"
     rRNA            complement(<1..>1035)
                     /locus_tag="KB913_002965"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DADVXE010000190         1003 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.197, whole genome shotgun sequence.
ACCESSION   DADVXE010000190 DADVXE010000000
VERSION     DADVXE010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.197"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            370..1003
                     /locus_tag="KB913_002966"
                     /pseudo
     CDS             370..1003
                     /locus_tag="KB913_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          182 c          184 g          295 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccgctac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta cct
//
LOCUS       DADVXE010000191          986 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.198, whole genome shotgun sequence.
ACCESSION   DADVXE010000191 DADVXE010000000
VERSION     DADVXE010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.198"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>986
                     /locus_tag="KB913_002967"
     CDS             <1..>986
                     /locus_tag="KB913_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBB6821238.1"
                     /translation="LEPGDFIMSGAGTIGRISRVPKQIKPGVFNQALIRLRINKEITD
                     SEYFIQFIRADFMQRKLTGANPGSAITNLVPMSEVKKWIVQFPILEEQKKIGNFFKQL
                     DDTIALQQRKLDLLKETKKGFLQKMFPKNGAKVPEIRFPGFTEDWEQRKFKEFSKKTG
                     KKNTKDLDFPAYSVSNKAGLISQTEQFDGSRLDDLEKTNYKFVEPNEFAYNPARVNVG
                     SIAFNNLGMTVIVSSLYVVVKMSEDLDNEFILQFIKSPTFIKEVKRNTEGSVREYLFY
                     ENFANIKFPFTRNKEEQQKIGAFFKQLDDTIALHQRKLDLLKETKKGFLQKM"
BASE COUNT          375 a          159 c          189 g          263 t
ORIGIN      
        1 ttagaaccag gcgattttat catgagtggc gctggaacaa ttgggagaat ttcaagagta
       61 ccaaagcaaa taaaaccggg tgtattcaat caggctttga ttagacttag aataaataaa
      121 gaaatcacag attcagaata ttttattcaa tttattcgtg cagattttat gcaaagaaaa
      181 ctcacaggag ctaatccagg ttcagcaatt acaaatctcg taccaatgtc agaagtgaaa
      241 aaatggatag tacaatttcc aatattagaa gaacaaaaga aaattgggaa cttcttcaaa
      301 caactggacg acactatcgc tcttcaacaa cgtaagctag atttattaaa ggaaacgaaa
      361 aaaggattct tacaaaaaat gttccctaaa aacggagcaa aagtgccaga aattcggttt
      421 cctggattta cggaagattg ggaacagcgt aagttcaaag agtttagtaa gaagactgga
      481 aaaaagaaca cgaaagattt agacttccct gcctattcgg taagtaataa agcaggttta
      541 atttctcaaa cagaacagtt tgatggtagt aggttggatg atttagaaaa aacaaattat
      601 aaattcgttg aaccaaatga attcgcctat aatccagcaa gagtaaacgt aggatcaatt
      661 gcatttaaca atcttggtat gacggtcatt gttagctctc tttatgtagt tgtgaaaatg
      721 agcgaggact tagataatga gttcatactt cagtttatca agtcaccaac atttatcaaa
      781 gaggtcaagc gcaacactga aggaagcgta cgagaatact tattctatga gaatttcgct
      841 aatatcaagt ttccttttac taggaataaa gaggaacaac aaaaaatcgg cgctttcttc
      901 aaacaactcg acgacacgat cgctcttcat caacgtaagt tagatttgct gaaggaaacg
      961 aaaaaaggct tcttacaaaa gatgtt
//
LOCUS       DADVXE010000192          972 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.199, whole genome shotgun sequence.
ACCESSION   DADVXE010000192 DADVXE010000000
VERSION     DADVXE010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..972
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.199"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            100..>972
                     /locus_tag="KB913_002968"
     CDS             100..>972
                     /locus_tag="KB913_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6821239.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSAASKRNN"
BASE COUNT          340 a          169 c          179 g          284 t
ORIGIN      
        1 ttattacgcc gattgtaaaa ttaagctaga caactaaaaa agtcatttgt gctacactca
       61 aaatagttcc gaccaaagaa ttataaggag tgagtacaaa tgacctatac ccatcttaca
      121 acggatgaac ttgtaataat agagtcttat ttcaaaatga atcaatctgt tgctaaaact
      181 gcccattgct tgaatcgttc aagacaaacg atccataaag tatatctgtt cttcaagcaa
      241 ggaaaatcag ccttagaata ttatcaacag tataagaaaa acaaatcaaa ctgtggtaga
      301 cgtccgcttg ttttacccga ggaacaatca gaatatattc aaagaaaggt tgttcaagga
      361 tggacacccg atgtgattgt tggtcgtgca gcgtttccta ttagttgttc tgctcgtacc
      421 atttatcgta tgttcaaaaa ggggctattt gattcttctg acttaccgat gaaaggcaag
      481 cgtaaaccga atggacatca agaaagacgt ggaaaacaaa ctttccgccg ctctattcat
      541 gaacgtgaaa aggattatag ccaattctca aatgagtttg gtcaccttga aggtgacact
      601 atcgtaggtc tgaaacataa aagtgctgta attaccttag ttgaacgatt atcaaaagtt
      661 atcatcacat tgaaaccgtg tggtagacaa gcgattgata ttgaaaaaaa attaaatcaa
      721 tggtttgaat ctgtaccgaa aaacctattc aaatccatca cttttgattg tggaaaggaa
      781 ttttcaaatt ggaaacagat cagtaatgtc aatgatattg ccatttattt cgctgatcca
      841 ggaacgccgt ctcaaagagg cctaaacgag aattctaacg gattgttacg tagagatggt
      901 ttattgaaat ctatggattt caattcagta gatgaatttt ttattcaatc tgccgcatct
      961 aaacgaaata at
//
LOCUS       DADVXE010000193          962 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.200, whole genome shotgun sequence.
ACCESSION   DADVXE010000193 DADVXE010000000
VERSION     DADVXE010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.200"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(13..86)
                     /locus_tag="KB913_002969"
     tRNA            complement(13..86)
                     /locus_tag="KB913_002969"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(50..52),aa:Ile,seq:cat)
     gene            complement(641..955)
                     /locus_tag="KB913_002970"
     CDS             complement(641..955)
                     /locus_tag="KB913_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821240.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          354 a          149 c          152 g          307 t
ORIGIN      
        1 tggctacatt aatgtaccct gtaggactcg aacctacgac cggacggtta tgagccgtct
       61 gctctgacca actgagctaa gggtagtggt tgttgccaca taaagccata aacaatcaac
      121 cagtagaatg cgtggcaaca aacctgttat cgcatatctt ggagtgtgac tatttatgag
      181 tgatagtgaa gatatgcgtc tccatatatg tatggttgag acagataaac atgtatgaaa
      241 aacgttgtta aatcaacgtt tttttatttt ggtcaaggag agaaaagtag agaaatacaa
      301 aattttttgc attgattttg cattcaaaaa aacattcaaa catttagaaa tccccaatac
      361 gtattcagga aaatctattt taaggtttac aaaaagaact tttgttcgta cactcttttt
      421 gaggtgaact tttatgctga tggaaggaaa aacacaatta tggtttaagc atgttccttc
      481 aaataagttt tttaattata aactctagag aaattaattc atcctaacat aaaataattg
      541 ttcactcaaa agtttttcta gaacaattaa aacagcaggc ttcacattcg ctatacattt
      601 gtaagaagta ataattcctg tactaaaagg cataattgct ttaattattt tttgacttct
      661 cttcaaacac aagaagtagt tgtgtaataa ttgcagaaat aaggattcca ataatagata
      721 taaaatttga catggaaacg tctataacat taaaagaata aagtgttgaa gaaagtaaac
      781 tgattgaaat aacccctccg taaaaaatag tctgtgaata tacccacttt ttttcagaag
      841 acgtacttcg tttggttcta aaacctatcc ctgcatttct actcttatca aaaaaccaaa
      901 tatttagaag taataatatt gctattatta agataaaatt actgtaaaaa tccaaaagct
      961 at
//
LOCUS       DADVXE010000194          959 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.201, whole genome shotgun sequence.
ACCESSION   DADVXE010000194 DADVXE010000000
VERSION     DADVXE010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.201"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(107..511)
                     /locus_tag="KB913_002971"
                     /pseudo
     CDS             complement(107..511)
                     /locus_tag="KB913_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
     gene            complement(570..>959)
                     /locus_tag="KB913_002972"
     CDS             complement(570..>959)
                     /locus_tag="KB913_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6821241.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          287 a          170 c          159 g          343 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttccattggg agcgtcaata attttgtgta
      541 aataaattgt cctcctgcaa aataattagt tactcagtaa acattgaaac taatgtatcg
      601 gttacctgtt gaaaaccttt atggcttctg tttagaaatt tttgattgta tgtatcaaaa
      661 atgctgacta gaaagcgttc tagtgattct tcattttgaa actgctcttt tctacggctg
      721 tatcttttaa tttgcttatt gaaagactcg attagattgg ttgagtaaat ggttctacga
      781 atgctaggtg gaaaatcata aaaagttaat aagtcttggt tttctatgag tgactgcgtc
      841 actttaggat agtttttctt ccatttctca atcatgccgg ataagaaggt attcgcttct
      901 tcttttgagt tagcttgata aacagcctta aagtcatcac agatttcttt tcggtcttt
//
LOCUS       DADVXE010000195          943 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.202, whole genome shotgun sequence.
ACCESSION   DADVXE010000195 DADVXE010000000
VERSION     DADVXE010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.202"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>943
                     /locus_tag="KB913_002973"
     rRNA            <1..>943
                     /locus_tag="KB913_002973"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DADVXE010000196          925 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.203, whole genome shotgun sequence.
ACCESSION   DADVXE010000196 DADVXE010000000
VERSION     DADVXE010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.203"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>925
                     /locus_tag="KB913_002974"
     CDS             <1..>925
                     /locus_tag="KB913_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HBB6821242.1"
                     /translation="DGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSAT
                     KLDDIIENPGDNIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDG
                     YTDAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPAGYHKVTFTAGEGTSIES
                     GTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDKS
                     DADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVVV
                     TYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          370 a          153 c          210 g          192 t
ORIGIN      
        1 aagacggcgt aagcttgcca gaagataaac ttccagtgtt gaaagcaaaa gatggttata
       61 cagatgcgaa atggccagaa gaagcaactc aaccaattac agcagatgat acagaatttg
      121 tatcaagtgc aacaaaattg gatgatatca ttgaaaaccc aggggataac attccggctg
      181 gctatcataa agtaaccttt actgcaggag aaggaacaag tattgaaagt ggaacaacag
      241 tctttgcagt gaaagacggc gtaagcttac cagaagataa acttccagtg ttgaaagcaa
      301 aagatggtta tacagatgcg aaatggccag aagaagcaac tcaaccaatt acagcagatg
      361 atacagaatt tgtatcaagt gcaacaaaac tggatgatat cattgaaaat ccaggagaaa
      421 acattcctgc aggctaccac aaagtaacct tcaccgcagg agaaggaaca agtattgaaa
      481 gtggaacaac agtctttgca gtgaaagacg gcgtaagctt accagaagat aaacttccag
      541 tgttgaaagc aaaagatggt tatacagatg cgaaatggcc agaggaagca actcaaccaa
      601 ttacagcaga tgatacagaa tttgtatcaa gtgcaacaaa actggatgat aaatctgacg
      661 ctgacaaata taatcctgaa ggtcaaaaag tgactacaga attgaataag gaaccagacg
      721 catttgaggg aattaagaac aaagaagatt taccaaaaga tactaagtat acttggaaag
      781 aaaaagtaga tgttagcgca gctggaaata aaaaagggac tgttgtagtg acatatccag
      841 atggatcatc tgatgaagtt gaagtagatg ttacagtgac agacaatcgt tctgacgccg
      901 ataaatatga gccaacagta gaagg
//
LOCUS       DADVXE010000197          910 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.204, whole genome shotgun sequence.
ACCESSION   DADVXE010000197 DADVXE010000000
VERSION     DADVXE010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.204"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            759..>910
                     /locus_tag="KB913_002975"
     CDS             759..>910
                     /locus_tag="KB913_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6821243.1"
                     /translation="MEEVCNMSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHE
                     QLDQLPP"
BASE COUNT          331 a          152 c          115 g          312 t
ORIGIN      
        1 ctgaattcgg aattaaaaac cacgataggt aactttaaac aaacatgaag agactttaat
       61 aagacttctt tatctgaaaa cacttttgtt tctctctttc ctttctacat cattaaatag
      121 tattttatac gttatctaaa atactattcc tctgtcaaaa taagctaact tacttcatta
      181 taaaatatcc acttatcgct ttcatgtata ttccaccgta aaaagtacat tttatcaccg
      241 agaactcatc atttttcatc atgatgaata ctatttacat atatctagtt caaagacaat
      301 aattattatg atccgttatt atctaagcac tatacagata ataggaattt ttcgtttcta
      361 aatattccaa tttgggaatc caataaaaat tttcgttcaa atacgtgtct attcgaactc
      421 ttttctagtt gttaattatg aagggggaag aaataaaaaa tacaatctat acacgaataa
      481 gaatattatc caaaaggagg ttttagaaaa gatttattat acgtaaaaag ctcaagacat
      541 tttcttagcc ataaggacat gtttgatatt taagaagata tatgaatttt cttttctaag
      601 tataaagata actatccatt atcaactaaa aaaacatttt tgaaaataaa catcagcagt
      661 cctatcaatg catgtgagct tatagaagtt attcgcagcg cagcataatt gcattagctt
      721 cttttcgtgt tttttgcctc ttttcccttt aaatcttaat ggaggaggtg tgcaatatgt
      781 cagataacga cgaacgcgta aatgcccagt tgattcgatt ctttgaaaag gtcattttga
      841 acaccgctaa tacttattat aaaaaacaag aagaaattca aaaacatgaa caacttgatc
      901 aactcccacc
//
LOCUS       DADVXE010000198          904 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.205, whole genome shotgun sequence.
ACCESSION   DADVXE010000198 DADVXE010000000
VERSION     DADVXE010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.205"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            89..406
                     /locus_tag="KB913_002976"
     CDS             89..406
                     /locus_tag="KB913_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBB6821244.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(497..862)
                     /locus_tag="KB913_002977"
     CDS             complement(497..862)
                     /locus_tag="KB913_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821245.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
BASE COUNT          336 a          111 c          153 g          304 t
ORIGIN      
        1 ttttaaaaca tcacaaggaa aaacttaact atggtattat ctaaacataa ttttttcggt
       61 atttaatatt taattaggag gtaatatttt gcttttttat agtaatttta tcttaatagt
      121 agcgatatta ttacttctga atatatggat ttttgatagg agtagaaatt caagtatagg
      181 ttttagaact aaacgaagtt tgtcttctaa aaaaaattgg gtatactcac aaactatttt
      241 ttatggagga attgttttaa ttagtttact ttcttcaaca ctttattctt tgaatattat
      301 agatgtttcc acctcaaatt caatatctat tattggaatc attattgctg caattattac
      361 acaactgttt ttagtgtttg gagagaagaa aagaagtaaa aaatagaaaa actagtgata
      421 gttttggtga tataagaaaa acatatatgt ataaaaagaa gaaagtagct tctctttgta
      481 catatatggt ttgtttttat ggatgccgag cttttttata agataaggct accgcccata
      541 acgacccaag gatttgtgga actaagtaaa tacctgcaag aagcaagatc agctgggtcg
      601 gttttaaagg atgatagaag taacgccatt cagtaaaatt ggcgcaaaat aaataggaag
      661 tgacagtaga tataatattg gcaatgaata aagatataat acgcctgttc ctttgaaaat
      721 aatatccagc aaaaagagat aaaaatatca atgtgatgaa cccgcttacg gaatgataac
      781 gaaaatcaag cagtaaggcg aaatgcacat aaggaacaaa agataaaagc aacggaaggt
      841 ttttccagca agtttttatc atctttcatc accacctaac aagtgttatt attttgttag
      901 tttt
//
LOCUS       DADVXE010000199          857 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.207, whole genome shotgun sequence.
ACCESSION   DADVXE010000199 DADVXE010000000
VERSION     DADVXE010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.207"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..116
                     /locus_tag="KB913_002978"
     CDS             <1..116
                     /locus_tag="KB913_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBB6821246.1"
                     /translation="KILIIDDVYTTGQTLFHAADCLQNAQPKIIRTISLAR"
     gene            244..795
                     /gene="raiA"
                     /locus_tag="KB913_002979"
     CDS             244..795
                     /gene="raiA"
                     /locus_tag="KB913_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBB6821247.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT          306 a          151 c          177 g          223 t
ORIGIN      
        1 aaaaaatatt gattattgac gatgtctata caacaggaca gacgcttttt catgcagcag
       61 attgcttgca gaacgcacag ccgaaaatca tccgaaccat ttctttggca agatgaatca
      121 gatgtggaaa tttgatagcg atttaatttg caaataacct agagttcgat ataatagaat
      181 taagaagagg gaaagagtgg tccttctcct tcttgattgt ggtagacgaa aggggtaatt
      241 tttatgttta gatataatgt acgcggcgaa aatatcgaag taactgaagc gattcgcgac
      301 tacgttgaga aaaaagtagg caaactagaa cgctatttca gtgacgcacc cgatgcaacg
      361 gcgcatgtga acttaaaagt ttatacagaa aaaacagcaa aagtggaagt aacgatccca
      421 ttaccttatc ttgtattacg tgccgaagaa acttctccag atttatacgc aagtatcgat
      481 ttggttgttg acaaattgga acgccaaatc cgcaaattca aaacaaaaat taatcgtaaa
      541 tcccgtgaaa cgggcatgaa tactgcagat gctgctgctt tattcaatga agaggacgaa
      601 aacgaaaatg attctgaatt agatatcgta cgtacgaaac gcctttcatt gaaaccaatg
      661 gatagtgaag aagcagtctt acaaatgaac atgctgggac ataacttctt tatttttgaa
      721 gatgcagaaa caaatggtac aagtatcgtt taccgccgta aagatggaaa atacggactg
      781 attgaaacag actgatcagc cttacttaaa taacaacgaa aacttgcagc agctactgac
      841 agctgccgca agttttt
//
LOCUS       DADVXE010000200          847 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.208, whole genome shotgun sequence.
ACCESSION   DADVXE010000200 DADVXE010000000
VERSION     DADVXE010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.208"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>847
                     /locus_tag="KB913_002980"
     CDS             <1..>847
                     /locus_tag="KB913_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBB6821248.1"
                     /translation="PLILNKREKNNLKKKMLIPFDSEVKGLLNKLTISNIDSTREKII
                     KIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITEEKEQQKAIKEQMIEEEK
                     VRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKELYANKIQELEEKLKELEV
                     IRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEPMDRIKELSSASVPFEFD
                     VHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLDEIEKVVLENYNGTVTFT
                     KLAKAE"
BASE COUNT          373 a           91 c          142 g          241 t
ORIGIN      
        1 cctcttattt taaataaacg agagaaaaat aatttaaaga aaaaaatgct cattccattt
       61 gattcagaag tgaaaggatt actcaataaa ctaactattt ctaatataga ctcgactagg
      121 gaaaaaatca taaaaatatt tgataaaatt aataatttat tcaagaatga caatgctgaa
      181 ttaaggaagg gtcttttaga gtttaaactt caagaactag aacttcatta ctcttattta
      241 gtgaaaatta ccgaagaaaa agaacaacaa aaagcaataa aagaacagat gatagaagag
      301 gaaaaagttc gtagagaaat tgatcgtgaa aagaaacgta ttgataaaga acaacgtcaa
      361 ttcaattctg aaatttccaa attaatcgca tatatgcaaa aagctaatgc agatgtggaa
      421 aaagaattat atgcaaataa aattcaagaa ctggaagaaa aattaaaaga attagaagtt
      481 atacgtgaaa atgtattaca aagagaatta aatactagag ccggttatgt gtatgtaatt
      541 agtaatattg ggtcttttgg tgaagacata tataaaattg gtatgactag aagattagaa
      601 cctatggata gaataaaaga attgagtagt gcatcggttc catttgaatt tgacgttcat
      661 gcgatgattt tttcagagga cgctccgtct ttggaaacta aattgcataa tcattttaga
      721 aaacaagaag ttaataaaat taatcaaaga aaagaatttt tcaaagtttc actagacgaa
      781 atagagaaag ttgttttaga aaattataat ggaacagtaa catttacaaa attagctaaa
      841 gctgaac
//
LOCUS       DADVXE010000201          751 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.209, whole genome shotgun sequence.
ACCESSION   DADVXE010000201 DADVXE010000000
VERSION     DADVXE010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..751
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.209"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            142..>751
                     /locus_tag="KB913_002981"
     CDS             142..>751
                     /locus_tag="KB913_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBB6821249.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARK"
BASE COUNT          260 a          110 c          125 g          256 t
ORIGIN      
        1 tctcagggca attctaagaa cgtttcaaga gatagcgaca ctatcgttat cgaaaaaggc
       61 gaaaacctat ctcattttct gctaatgtaa gttggtttag cttttgttaa tatgacttta
      121 tgaaaatgga ggtaattaaa tatgattttt cctaaagtta atgaagcaag cttgaataaa
      181 ggatcctttt ttcatatcta tgaaaacgaa gattttgaac tgtataatat cctttcacaa
      241 aaagaggtca tcgaaaacca aataatctgc catccaatta tttacaaatc tattttcaag
      301 tatgcatttt ttgcttccaa tgattttcaa agaatggaga ttaccgactg tatattcgaa
      361 aactgtgatt tttcaggctg tatattgaca aaaagcatgt tgcatcgcgt gaaatttgtc
      421 aattgtaaat taacaggtac taaattgatg gaaagttata ttgggaacac gttattcgag
      481 aattgtaaaa tggactatgt aaatttatct ggttcaaaca taaaagaaag tacctttgag
      541 cactctgtct tatcaagcgc agattttgta gactgttccc tcactaaaat aatgttttct
      601 actaatgatt tagaaaatgc tagctttttt gatactgatt taaaaaatat cgatttaagt
      661 agcaactcct ttgaaatgat tgaagtacgc tcggaacatc taaaaaattg tacgcttaat
      721 cagttgcaag cacttggttt tgctagaaaa t
//
LOCUS       DADVXE010000202          731 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.212, whole genome shotgun sequence.
ACCESSION   DADVXE010000202 DADVXE010000000
VERSION     DADVXE010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.212"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            212..>731
                     /locus_tag="KB913_002982"
     CDS             212..>731
                     /locus_tag="KB913_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821250.1"
                     /translation="MYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILP
                     LILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEI
                     FLIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSID
                     SELLSFGIGLTLL"
BASE COUNT          227 a          104 c          109 g          291 t
ORIGIN      
        1 cattaatcgt gcgttaagtt tagaatctat ttttagctcc cctattaatt ttgaaacgtt
       61 tagatcatat ggcatgcaag taaataattt ttacccatgg ttaactctat atcctttatt
      121 tttattgatc aagtttacta atttagcaat aggctataac ctttttcttt atattgttac
      181 gctcattact ctatttatat gtcattatgt aatgtatgaa attaccaaaa aacatgttac
      241 tagctccttt ttcgctatta tatatacaac atcttctttt aggagtgtag aaatatttct
      301 tcgaggggca atgggggaat tactcgcaat gtcaatactt cctcttattt tactcgggtt
      361 tataaagctt tacgactcaa aaaaagaatc ttgggttatg ttggcgatta gcatgacttt
      421 attaatttac actcatgttc tttctgtagc tatgactatg gtaatgatta taattgcttt
      481 aattattcaa ttttatcgga aaaagaaaat agaaatcttc ttaattatta aattaataaa
      541 agctgctata gttactttac ttctttcact agcgtttata ggtcctatga ttgagcagac
      601 attgtatcaa gatctgaata gaccttatgt ggatatatta caaaaaagag caatttatct
      661 gggtaaagag tttttgattg gaagtataga ttcagaatta ctatcatttg gtattggctt
      721 aactttgctt a
//
LOCUS       DADVXE010000203          714 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.213, whole genome shotgun sequence.
ACCESSION   DADVXE010000203 DADVXE010000000
VERSION     DADVXE010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.213"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            54..710
                     /locus_tag="KB913_002983"
     CDS             54..710
                     /locus_tag="KB913_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6821251.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
BASE COUNT          309 a           69 c          127 g          209 t
ORIGIN      
        1 tgttaatcaa gaagcctaaa gaaatcttat caaaaataag ttaggagaaa ataatggata
       61 tattagaaat aaagaatgta gcatatagtt atgcaaattc taaagaaaaa gttttgtcag
      121 gagtaaatca aaaatttgaa cttgggaagt tttatgcgat agtaggaaag tcaggaacag
      181 gaaaatctac acttctttcc ttacttgctg gacttgataa acctcaaaca ggaaaaatat
      241 tgtttaagaa tgaagatata caaaataaag gatatagtaa tcatagaaaa aataatatat
      301 ctttagtatt tcaaaactat aatttaatag attatttatc accaattgaa aatattagat
      361 tagtaaataa atcagcagat gaaagtatct tgtttgaact aggtttagat aaaaaacaaa
      421 taaaaagaaa tgttatgaaa ttatctggtg gacagcaaca aagagtagct attgctagag
      481 cattggtatc agatgctcca ataatactag ctgatgagcc tactggtaat ctagacagtg
      541 ttactgctgg agaaataatt aatatattaa agacattagc taaagataga aataaatgtg
      601 taatagttgt aacacatagt aaggaagtag cagattctgc ggatatcatt ttagaactaa
      661 gtggtaaaaa gttgaaaaaa gtaaataaaa tgaatttgga ggttgaataa tgat
//
LOCUS       DADVXE010000204          670 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.214, whole genome shotgun sequence.
ACCESSION   DADVXE010000204 DADVXE010000000
VERSION     DADVXE010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.214"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(248..547)
                     /locus_tag="KB913_002984"
     CDS             complement(248..547)
                     /locus_tag="KB913_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBB6821252.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT          224 a          119 c           75 g          252 t
ORIGIN      
        1 tccaattttt aacttacaaa aatgcaacat taataaataa cgatagtttc ataaaataca
       61 cttttaatta acattattag tttatactag ctgtttttgt gttaattaaa ggataaaata
      121 caatataaag aaacatctgt ttctttattt agaataaaaa aatacagact ctgttcaaat
      181 aaatgaacct agcctgcatt atgagattga ctatactttt taattcattg agatgaataa
      241 ctcgttttta taaatgccca aaagtaatcg gtgccgaagc cattcctcga cctaattctt
      301 tttcaaattt tcctattgtt gatatctcca tataaaacgg tgatactggt ttagacaatt
      361 ctcccctgat tgctaacgga cgtaaactac gttccaaatt atttatgact ttaggataat
      421 actgaccttt ttctaagcct gtctttgcgt ctatcaaaag tatacgttcc ttttctttga
      481 tctctggatt taaaacgaga tcatataatt ttagtaccat gttttctatt tcttcacttt
      541 tagacatcac gatttcctcc caaaaatata tttcttccca ctacattcta taaacaaagt
      601 atacgctaca tctagatttt tttaaatcat tactggattg ttaaaacctt tcaatacact
      661 gttatggcaa
//
LOCUS       DADVXE010000205          649 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.215, whole genome shotgun sequence.
ACCESSION   DADVXE010000205 DADVXE010000000
VERSION     DADVXE010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..649
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.215"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>649
                     /locus_tag="KB913_002985"
     CDS             <1..>649
                     /locus_tag="KB913_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBB6821253.1"
                     /translation="MQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQ
                     WRYALKISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMST
                     NNAWVPWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGL
                     SLVVPITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLG"
BASE COUNT          206 a           80 c          125 g          238 t
ORIGIN      
        1 tgatgcagac attatatttt gatgataaat atgttggcag agtagtcggc ggaacactgt
       61 catttgtgtt gataggttta gtaatttatt taagaataat gataaagggt gctcattttt
      121 ttgataaaaa acagtggaga tacgctttaa aaatctcttt gccgctaatc ccacattcct
      181 tagcaaatat agttttagca caattcgata gaattatgat taattcttat ttaggtcctg
      241 ctgcgggggg aatatattcc tacattagta acataggtat tattctaagc gtaatatgga
      301 tgtctactaa taacgcctgg gttccatggt tctatggtga gatgagtaaa aataatgaaa
      361 aaaaagtgaa gaaagttagt aactattatt tagtagtctt tactttgatt acgatgattg
      421 taatggtagt ttcgattgat ttagcaaaat ttatggctcc gaaagactat tattctgggt
      481 tatctttagt ggttccgata accttaggct atttctttca gtttttatat agtttaccag
      541 ttaatgctga attttatgag aaaaaaacat cgtttattgc gattggtaca gtagcaagtg
      601 ctatagttaa tatactatta aacatgattt tcatacctag gttaggaat
//
LOCUS       DADVXE010000206          647 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.216, whole genome shotgun sequence.
ACCESSION   DADVXE010000206 DADVXE010000000
VERSION     DADVXE010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.216"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(14..400)
                     /locus_tag="KB913_002986"
     CDS             complement(14..400)
                     /locus_tag="KB913_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821254.1"
                     /translation="MKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRFEVLKIQKNE
                     LLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTDVVMITDIYV
                     EDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          202 a          122 c           80 g          243 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg ttcctttatt tttattaaca agttttatca
       61 caggcttcat atatttgatt atatcttcat cttctacata gatatctgtt atcattacga
      121 catctgtact atttcgattg agtactttca cttgatctcc agcattgatt ttccctctaa
      181 atcttttagg aatgaaccaa ctatacatat gattagcatc accaaaatgt gcttttatcg
      241 cattctcagg atataactta ttcaatagtt cattcttttg aattttcaaa acttcaaatc
      301 tatacttatc atcttctgct aatctaaata aatcttctaa acgcatgttt tctaactgta
      361 agttttgaaa atcttccggt ataaattttc tatatttcat taataatgaa cgcccagccc
      421 gatttattag aatctggcca ttttggtcat ctctataaag aattccgtaa cccatcaacg
      481 ccaatagcac acgtgacgtt ttgttacttg taatattcat atttccttga ttacctgagg
      541 caatgaaaga cttatctact tgaattaggg tgaaattctc attcaaatat ggtagtaaaa
      601 ttaatatatg tgaaaatcga atcttgagat agctattccc cttgaga
//
LOCUS       DADVXE010000207          625 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.217, whole genome shotgun sequence.
ACCESSION   DADVXE010000207 DADVXE010000000
VERSION     DADVXE010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.217"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            1..625
                     /locus_tag="KB913_002987"
                     /pseudo
     CDS             1..625
                     /locus_tag="KB913_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          247 a          105 c          118 g          155 t
ORIGIN      
        1 gtaaagcaat ctaaaacgag tggttcattc aaagaaaaag ataatcttac gcctgaacaa
       61 aaagaattgt tagaactacg taaaagaaac cagcaattag aaatggaaaa tgatatttta
      121 aagcaagcag cgctgatatt cggacgaaga gacaagtaat cgatgcgaat aagcatcttt
      181 accctatatc agcgatgtgc agaatattag gtctatcacg tcagtcctat tattatcaat
      241 caaaaccaaa gaaagacgaa tcagaacttg aagaagtagt cgctgaagaa tttatccgca
      301 gccgaaaggc ctacggctca agaaaaataa aaaaagcctt atcaaaacga ggcattcaga
      361 tcagccgacg aaaaattagt agaatcatga aaaatagagg attaaaatcg agctatactg
      421 ttgcttattt taaagtacat cattctactt gcaatgaagc caaaacgaca aacgtattga
      481 atcgtaaatt cttaagagac aacccattag aagcgatcgt aacagacttg acttatgtac
      541 gagtcgggaa aaaatggaat tatgtctgtt tcattttgga tctgttcaat cgagaaattc
      601 tcggctattc ttgtggagaa cataa
//
LOCUS       DADVXE010000208          624 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.218, whole genome shotgun sequence.
ACCESSION   DADVXE010000208 DADVXE010000000
VERSION     DADVXE010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.218"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..611)
                     /locus_tag="KB913_002988"
     CDS             complement(<1..611)
                     /locus_tag="KB913_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821255.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQ"
BASE COUNT          267 a           94 c          119 g          144 t
ORIGIN      
        1 ttttgtttgt tttttctttg ccacataaat acacctagac tgacgatgaa gagcatatcc
       61 aacagatttc ctgcgacttg gatcgtcgaa gggttggtca gtggcattaa agcaaggaca
      121 aaaaaggaaa acaagctgta aataaaacag gtgacaggaa ctaatcgaaa gaagagcgga
      181 catttcaatt ggctaaaaat gagtgaaaaa ataaaataag taaaaatgga taaaatcacg
      241 actaaaccat tcatgataaa gaagaaaagc gtattgtgat taaacgaata aaaaagaatt
      301 gctaaaaaag aaaacgtttt aaatgcaatc aatacgcttg aagcttcgtt taacgtacca
      361 ggatgtcgat gaaaaaaata ggcaccgaaa taaacagaaa acagtaagcc gcaaagagaa
      421 gacaaaatca aaaaaaacgg attttcttcg gcttctgtga tatcagaatg atccaaaagc
      481 aaccagccta atgcactaga aggcgcatgt gaggtcttaa ggtatgaata acatagaaaa
      541 aataagatcg tcaaagttgc aaaaaaagag cctaaatgta aaaaattagt ggttctacgt
      601 tgaatttcca taatatctcc aaat
//
LOCUS       DADVXE010000209          572 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.219, whole genome shotgun sequence.
ACCESSION   DADVXE010000209 DADVXE010000000
VERSION     DADVXE010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.219"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
BASE COUNT          185 a           81 c           81 g          225 t
ORIGIN      
        1 ttttcttgat gtgatatcct tgtctttttt gtaatgtttt taacttattg cttttgcaaa
       61 atttatttac ctgttttctg gatcaacgat agtgtacatt atgctatcct tgtttggatt
      121 ttaggacgtt taaagaggca cttttttaca taacttaatc catagacctt ttaagcatgc
      181 tgtgagataa taataaagaa gagtttaaag cgcaccccaa accacttccc cataagtgta
      241 ttacgcttta aactctttta tatttgaatt cactaagaag cataccatat ttttgaaaaa
      301 aagtgagaaa aaaggcttat aattaggatt tagagtaatt aattagatgt ttattttata
      361 ggactgatac tatagattac aaatagtatc gtatttcgca atcttaaaat tatcttctta
      421 ctgtgaataa gataataaaa tttgtatttg tcctttttag gtaacttatt ttaatctata
      481 tacctttctg gatcaacgaa agtatacttt atatagtcat aacgccgatg gtaactatgc
      541 actgtaacga taatgctgct aaaatatctt tt
//
LOCUS       DADVXE010000210          550 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.220, whole genome shotgun sequence.
ACCESSION   DADVXE010000210 DADVXE010000000
VERSION     DADVXE010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.220"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            69..539
                     /locus_tag="KB913_002989"
     CDS             69..539
                     /locus_tag="KB913_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBB6821256.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT          200 a           99 c           84 g          167 t
ORIGIN      
        1 ggaaaacaaa tagctagttt tcagtttagc gctcttttta ttatataaaa tagaaaggag
       61 aaaactttat gtctatttat aattttgaaa ctactttaga agacggcact gtctattcat
      121 tgaaaaaata tgcaggcaaa ccgataatca ttgttaacac tgcaacaaaa tgcggtctag
      181 cacctcaatt taaacaatta gaagaacttt accaagctta tcagacacaa ggtctggtta
      241 tcttaggctt tccttccaat caatttaaac aagagctaga ttcagcgact gaagcagcag
      301 aagcttgtaa aaccacttat ggcgttacct tccctatgca tcaattgatt gacgtaaatg
      361 gagaaaatac agatcctctt tttacttatc ttaaaaatga agctcctggt actgtcacta
      421 aagcaataaa atggaatttt actaaatttt tgattgatag aaatggcaaa gtaatcgaac
      481 gatttgcacc acaaacttct ccattgaaaa tgaccgctgc aattgaatcc gttctttaac
      541 ttaataaaaa
//
LOCUS       DADVXE010000211          509 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.222, whole genome shotgun sequence.
ACCESSION   DADVXE010000211 DADVXE010000000
VERSION     DADVXE010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.222"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..132)
                     /locus_tag="KB913_002990"
     CDS             complement(<1..132)
                     /locus_tag="KB913_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBB6821257.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          183 a           93 c           91 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactatta
//
LOCUS       DADVXE010000212          487 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.223, whole genome shotgun sequence.
ACCESSION   DADVXE010000212 DADVXE010000000
VERSION     DADVXE010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.223"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(<1..>487)
                     /locus_tag="KB913_002991"
     CDS             complement(<1..>487)
                     /locus_tag="KB913_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HBB6821258.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IK"
BASE COUNT          142 a           92 c           86 g          167 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggat
//
LOCUS       DADVXE010000213          486 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.224, whole genome shotgun sequence.
ACCESSION   DADVXE010000213 DADVXE010000000
VERSION     DADVXE010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.224"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
BASE COUNT          161 a           96 c           56 g          173 t
ORIGIN      
        1 ctaaatcact ctacaataac ggcgaaagca caaaaaataa aaaaattatt acgttattaa
       61 aaaaacagat gaaagatcag gttttattag atctcattct ttcatcactt gaagggattt
      121 aatgaactac tttttcctct ttgtcgtttt tatatattcg tattccttca aacagtagga
      181 tagcctcttt caatgcttga tatttgaact gtccgttact taaaaattta gatgtgccgc
      241 cctcttccta gaacatattc ttttttactt tttcattaat tgacagacca atcgaacgaa
      301 actgtaaatt tcgataggat aatgattggt caaactcatt cattttcaag acatctcgat
      361 tcatattcaa gataggaatc tttttatcaa catcacttta ttcgtatttt cctctaccat
      421 aaaagcttca cgctccacaa aattgtttta tacactacta ttcagcccat tcaacgacca
      481 atgaat
//
LOCUS       DADVXE010000214          464 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.227, whole genome shotgun sequence.
ACCESSION   DADVXE010000214 DADVXE010000000
VERSION     DADVXE010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.227"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..>464
                     /locus_tag="KB913_002992"
     CDS             <1..>464
                     /locus_tag="KB913_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6821259.1"
                     /translation="LVTKGDLNELFRSHLEKAINTLLRTELTAFLDYEKYDRTGFNSG
                     NSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLETTIIHLFEKGVT
                     MSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAIFMDAT"
BASE COUNT          168 a           85 c           77 g          134 t
ORIGIN      
        1 ctagtcacta aaggcgattt aaatgaatta ttccgttcgc acttagaaaa agcgataaac
       61 acactcctac ggactgaatt aacggctttt ttagattacg aaaaatatga tcgcactggt
      121 tttaattcag gtaattcgag aaacggttct tactttcgat caatcaaaac cgaatatggt
      181 gaattaacat tggaaatacc tagagatcgt aatggtgagt ttaaacaaca aactttacca
      241 gcctacaaaa gaacaaacga tacattggaa accactatta tccatttatt cgaaaaaggt
      301 gttacgatgt ctgaaattgc tgatttgatc gaaaaaatgt acggtcatca ctatactcca
      361 caaaccatgt ccaacatgac taaagttctg actgaagaag taaatgcctt taaatccaga
      421 gccttaaatg ataagtatgt cgctattttt atggacgcta ctta
//
LOCUS       DADVXE010000215          450 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.228, whole genome shotgun sequence.
ACCESSION   DADVXE010000215 DADVXE010000000
VERSION     DADVXE010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.228"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(35..271)
                     /locus_tag="KB913_002993"
                     /pseudo
     CDS             complement(35..271)
                     /locus_tag="KB913_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          146 a           76 c           77 g          151 t
ORIGIN      
        1 tagaaggact gaccttctgt ctcagatttt tttgttattt cacttgaatc aattgattga
       61 tcaaaaaaat cctgattttc atgttctcaa atgatttaaa tccataagat aatcgtttca
      121 gtgtcttgat atggggaatc ttggcctcta ttttgccatt agaatacggg taaatcatag
      181 cattgtaaat accttcttca tacgttaaaa ggttttgaag tttcgtgcga agttgtgcat
      241 caagtgtttc aggaagattt tttaataacg ccgtttgtat aattaagcga gacaaataaa
      301 aaagccattt atgttacact ccaattgtaa tacccgctaa agcatacaag gagagtgaac
      361 ataaatgact tatacccatc ttacaccaaa cgagcttgta atgatagaag catattttca
      421 tcaagaaact ccggttgcta tcgttgcgaa
//
LOCUS       DADVXE010000216          441 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.230, whole genome shotgun sequence.
ACCESSION   DADVXE010000216 DADVXE010000000
VERSION     DADVXE010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.230"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            198..441
                     /locus_tag="KB913_002994"
                     /pseudo
     CDS             198..441
                     /locus_tag="KB913_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
BASE COUNT          172 a           60 c           76 g          133 t
ORIGIN      
        1 aaatttaaac tttatattat aataatgaag cttaatcttc tttatagaga attgggctat
       61 ttttaatggc aaagagggga agaagatgtt tcaaaacaaa ggacaacgct atgttgtaaa
      121 aggagtaaag gaatcttact ggaatcaaaa atctttattg agaaaattat ctttgaattt
      181 aagcacaaag aaatgaaggt acactagata gcaatgaaga tatctttgtc attaaacgtc
      241 gctattttac acaagtaagt gatgatttga ttcatgtctt ttccaatgag tggtttgttt
      301 ctgagaaaaa attacatgct tctaatctgc aatatatgcc aggtgaagat ccaattccta
      361 atatgaaagc aattatcaac agtaaggatt acgaaggata taaagccaaa catccagaag
      421 cgaaaccatt taaataccca c
//
LOCUS       DADVXE010000217          414 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.231, whole genome shotgun sequence.
ACCESSION   DADVXE010000217 DADVXE010000000
VERSION     DADVXE010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.231"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(109..>414)
                     /locus_tag="KB913_002995"
     CDS             complement(109..>414)
                     /locus_tag="KB913_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6821260.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          116 a           96 c           82 g          120 t
ORIGIN      
        1 gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gctacgattg cccttgacaa
       61 tgagcatcct cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc
      121 tccagaggta tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg
      181 aatttggatc ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg
      241 cacataatca aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac
      301 gaattctact ttgacagatt tataggttga ttccacaacg gcattatcat acggacaacc
      361 cttcctactc aatgaacgag taattccaaa accattcaga atctcatgaa tggt
//
LOCUS       DADVXE010000218          401 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.denovo.232, whole genome shotgun sequence.
ACCESSION   DADVXE010000218 DADVXE010000000
VERSION     DADVXE010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.denovo.232"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
BASE COUNT          172 a           53 c           67 g          109 t
ORIGIN      
        1 atttctgttg ttttaagtag caaagcaata aaatagtatt ttaaaaaaca tataaaatag
       61 ttgttgacat gttagaaatg acatgataag ataactgagt tgttaaaaaa gaaccacttg
      121 tgaagcttga ttctatcgaa aaaaacttca aaaaagttct tgacaaataa caaatgataa
      181 gttatgataa atgagttgct gtaagatttc gaaaaacgaa atcaaaaaaa cttttaaaaa
      241 agagttgaca attacttgtc tctctgatat gatataaaag ttgctacggc agccaaaaac
      301 gaatcgggga acactcctga tgaagtagac ctttgaaaac tgaacaaagt aagacaaacc
      361 aaatgtgtag ggcgtcttga ttcaattcaa gacaacaaac a
//
LOCUS       DADVXE010000219        26362 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.guided.035, whole genome shotgun sequence.
ACCESSION   DADVXE010000219 DADVXE010000000
VERSION     DADVXE010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.guided.035"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            1..223
                     /locus_tag="KB913_002996"
                     /pseudo
     CDS             1..223
                     /locus_tag="KB913_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
     gene            480..668
                     /locus_tag="KB913_002997"
                     /pseudo
     CDS             480..668
                     /locus_tag="KB913_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            714..1679
                     /locus_tag="KB913_002998"
     CDS             714..1679
                     /locus_tag="KB913_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6821261.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            1701..1913
                     /locus_tag="KB913_002999"
     CDS             1701..1913
                     /locus_tag="KB913_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBB6821262.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            1988..2464
                     /locus_tag="KB913_003000"
     CDS             1988..2464
                     /locus_tag="KB913_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBB6821263.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            2461..4269
                     /locus_tag="KB913_003001"
     CDS             2461..4269
                     /locus_tag="KB913_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBB6821264.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            4346..4561
                     /locus_tag="KB913_003002"
     CDS             4346..4561
                     /locus_tag="KB913_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBB6821265.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            4653..5516
                     /locus_tag="KB913_003003"
     CDS             4653..5516
                     /locus_tag="KB913_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821266.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            5553..6089
                     /locus_tag="KB913_003004"
     CDS             5553..6089
                     /locus_tag="KB913_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HBB6821267.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            6103..6525
                     /locus_tag="KB913_003005"
     CDS             6103..6525
                     /locus_tag="KB913_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBB6821268.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            6455..8854
                     /locus_tag="KB913_003006"
     CDS             6455..8854
                     /locus_tag="KB913_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBB6821269.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            8886..10877
                     /locus_tag="KB913_003007"
     CDS             8886..10877
                     /locus_tag="KB913_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6821270.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            10900..11151
                     /locus_tag="KB913_003008"
     CDS             10900..11151
                     /locus_tag="KB913_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBB6821271.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            11141..12370
                     /locus_tag="KB913_003009"
     CDS             11141..12370
                     /locus_tag="KB913_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBB6821272.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            12367..14448
                     /locus_tag="KB913_003010"
     CDS             12367..14448
                     /locus_tag="KB913_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBB6821273.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            14597..18517
                     /locus_tag="KB913_003011"
     CDS             14597..18517
                     /locus_tag="KB913_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBB6821274.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            18518..19462
                     /locus_tag="KB913_003012"
     CDS             18518..19462
                     /locus_tag="KB913_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821275.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            19466..19669
                     /locus_tag="KB913_003013"
     CDS             19466..19669
                     /locus_tag="KB913_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBB6821276.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(19969..20205)
                     /locus_tag="KB913_003014"
     CDS             complement(19969..20205)
                     /locus_tag="KB913_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6821277.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(20388..20774)
                     /locus_tag="KB913_003015"
     CDS             complement(20388..20774)
                     /locus_tag="KB913_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBB6821278.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            complement(20756..22084)
                     /locus_tag="KB913_003016"
     CDS             complement(20756..22084)
                     /locus_tag="KB913_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBB6821279.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(22045..22374)
                     /gene="mobC"
                     /locus_tag="KB913_003017"
     CDS             complement(22045..22374)
                     /gene="mobC"
                     /locus_tag="KB913_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBB6821280.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(22632..23002)
                     /locus_tag="KB913_003018"
                     /pseudo
     CDS             complement(22632..23002)
                     /locus_tag="KB913_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            23147..23332
                     /locus_tag="KB913_003019"
     CDS             23147..23332
                     /locus_tag="KB913_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6821281.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            23490..23657
                     /locus_tag="KB913_003020"
     CDS             23490..23657
                     /locus_tag="KB913_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821282.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            24275..24934
                     /gene="vanR"
                     /locus_tag="KB913_003021"
     CDS             24275..24934
                     /gene="vanR"
                     /locus_tag="KB913_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBB6821283.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            24937..26298
                     /gene="vanS"
                     /locus_tag="KB913_003022"
     CDS             24937..26298
                     /gene="vanS"
                     /locus_tag="KB913_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBB6821284.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
BASE COUNT         6535 a         6980 c         7206 g         5641 t
ORIGIN      
        1 agatgatgtc agttcgacag taataacaag agatgattat gaaaaatatg atgattcgta
       61 cgcgttattt aaagaaactt taaaaggaga tttgttaaca aaaacttttc tctttttagg
      121 atttagtttt acagacccta atttagaaag aattttatca gatataagat gggttttgag
      181 agaaaaccaa agacctcatt attgtataat gagaaaaata ttatagaaaa aattttaggt
      241 tatcgctgaa agccccggaa atacgggcat ttcgcaggat atgagaactc aatttactac
      301 caatttacta ctttcggatt gagccgcata tatgctgaac catactgcta atacccgcca
      361 ccccaaatac ggcacatcat aaattgaata cgacaccgta aacgcggcgt tcctctttcc
      421 cgtcatggga gaacaggacg ccgctttttt atgcccaaat agagaaagga ggcgacgcca
      481 tgctatttac ttccggccct gaccgggcgt ttgaacggct gatgcaggaa aagcccggtt
      541 tcgatcacta cgacggcggc ggggcggacg cgccggagga ttgcggcacc tgccgatttt
      601 accgcccgga ttggaaatat caattctgcc agtttgcaga gtgtccctat cagccgggca
      661 agctgaccga ctatgcagcg gtcaaattca cagtgaaagg agcgaacaac gctatggcag
      721 ttttccgtgt ggaaaagaac aaaggctata cggtgatgtc aaatcaccac ctgcggaata
      781 agaacctgac cttaaaggcc aagggcctgc tgtcgcagat gttgtccttg ccggaggatt
      841 gggactatac cctaaaagga ctgtcctata tcaaccggga aagcatcgac gcgatcagga
      901 cagcggtatg ggagcttgaa aaagctggat atatccggcg tgagcagggc cgtgacgcaa
      961 aaggcaaaat ggccgatatg gtctatacca tctacgaaca gccggtattg gaaaacccgg
     1021 tattggaaaa tccaacatcg gataacccgg tgttggaaaa tccgacatcg gataatccgg
     1081 cgtcggaaaa tccaacgcaa ttaaataaag aagtacaaag aactgactta tcaaaaaaag
     1141 aaaaaataat tacagatgga caaagtaccc attccattcc tatcccatcc ccgacccctg
     1201 cccctatgga gggcgaggca gcggctacgc cgccggaacg gaaaaggaca ggaaaggatg
     1261 aggctgtacg gatttatcgg gaaatcattt tggagaacat cgagtatgcc tatctcattc
     1321 aggacaggag cattgaccgt gaacagcttg acgaaatcgt agacctgatg ctggaaaccg
     1381 tctgcaccgc ccgaaagaca atccgtgtcg ccggggacga ctaccctgcc gagctggtga
     1441 aatccaagta catgaagctg accggcgaac atatccgctt tgtccttgac tgtctgcggg
     1501 agaacacaac gaaagtccgc aatatcaaac aatacctgcg ggctatgctg ttcaacgccc
     1561 ccagcaccat ttccaactac tacacggccc ttgtcgcgca cgacatggca cagcccgatt
     1621 ggggaaagcc taaatccggc ctgccggact attcctgcgg cgagggcgaa agcctgtaac
     1681 gagaaaagga ggacgaccct atgaagcagg gcgcattgat ttttgacgag cgaacagacc
     1741 gttacgacat ccgctttgat ctggccgact attacggcgg cctgcattgc ggggagtgtt
     1801 tcgacgtgat gatcggcggc aaatggaggc ccacccgcat tgaaatggcc gaaaactggt
     1861 atcttgtcgg catccgggcc gacgaccttt ccggcctgcg ggtgcggatt tgacctatat
     1921 ctacctgcgg cgtctggtgg ttccgcctta gacgccgctt ttgactttct gacaaggagg
     1981 gatgcgattg caggaagaag ttactcaaaa gaccattgcc ctgtccatga aaacgggcaa
     2041 gctcacggct caagtgctgc aagcggcgct gaaaaagtac ctgcaacacc gggccaaggg
     2101 caaaaacacg ctgcaccacg gccagcagag cctaaagcag cttaaaaagc atggggctga
     2161 tctctccaac attgagatca ccgaggccaa cattggagcg ttcaagccat gcgccaagaa
     2221 atacggcgtg gattttacct tacgaaaaga taagaccacc cagccgcccc actacgttgt
     2281 gattttcaag gccaaggatg cagataacct tgatctggcg tttcgggagt ttaccgccaa
     2341 gacgctttcc aaggagcagc ggccctctat ccgcaaggtt ttgtccgctg tgaagcaaaa
     2401 ggcggcggcc cagaccaagc agcgggccaa ggagaaaatc aaggaaaggg ggctggaact
     2461 gtgaagcctg acgtaaagaa attgctgatc ctgaacctcc cgtatctgat ttttgtgtac
     2521 ctgtttgcga aatgcgggga ggcgtaccgg ctggccgctg gtgctgacct gtcggggaag
     2581 ctcctgcatt ttgcggatgg ttttgcggcg gcttttgcca acccgctgcc aagcctgcac
     2641 ctgtttgacc tgtgtatcgg tatcgccggt gccgtgatcg tgcggctggt ggtgtactgc
     2701 aagagcaaga acgtgaagaa ataccgcaaa ggcatggagt atggcagcgc ccgctggggg
     2761 acggccaaag acatagcgcc ttacatcgac cccaagtttg aaaataatat cctgctcacc
     2821 caaacggaac ggcttaccat gaccggcagg cccaaagacc ccaagacagc gcggaataaa
     2881 aacgtgctgg tgatcggtgg cagcggttca gggaaaacga gatttttcgt gaaacccaac
     2941 ctgatgcaat gctttccgac cacggactat ccgacttcgt ttgtggtgac agatccgaaa
     3001 ggcactttgg ttctggaaac cggcaggatg ttccagcagg cgggctaccg cattaaaatc
     3061 ctgaatacca ttaacttttc caagtccatg aagtacaacc cctttgtcta catccattcg
     3121 gaaaaggacg tgctaaagct ggtaaatacc ctgatttcca acaccaaggg cgagggggaa
     3181 aagtcagcgg aggatttttg ggtgaagtcg gaacggttgt tttattcggc cctgatcggc
     3241 tatatctggt acgaggcccc agcggaggaa atgaacttct caacgctgct ggaaatgata
     3301 aacgccagtg aagcccgcga ggacgacccg gagtttcaaa gccccgtcga tctcatgttt
     3361 gagcgtttgg agcagaaaga ccccgaccat tttgcggtgc gccagtacaa gaaattcctg
     3421 ctgtccgcag gcaagacccg ttcttccatc ctgatttcat gcggtgccag acttgcgccc
     3481 tttgacatcc gggaggtacg cgagctgatg gaggacgacg aaatggagct ggacaccatc
     3541 ggggacgaaa agacggtgct gtatctcatt atgagcgata cggacacgac ctttaatttc
     3601 attctggcta tgctccaaag ccagctaatc aacctgcttt gtgaccgggc tgatgatgtg
     3661 tacggcgggc ggctgcctgt ccatgtacgc ctgattttgg atgaatttgc caacattggc
     3721 caaataccca atttcgataa actcattgcc accattcgaa gccgtgaaat atcggcctct
     3781 attattttgc agagccagtc gcagctaaaa gcgatttaca aggacgccgc cgagatcatt
     3841 tcggataact gcgatagtgt gcttttcctt agtgggcgcg gcaaaaatgc caaggagatt
     3901 tccgatgcgc tggggaaaga aacgattgac agtttcaaca ccagcgagaa ccggggaagc
     3961 caaacgtccc acggattgaa ctatcaaaaa ttaggaaagg agttgatgtc ccaagacgaa
     4021 attgccgtga tggacggcgg caagtgtatc ttgcagctac ggggtgtgcg cccgttttta
     4081 tcggagaaat tcgatattac caagcatccc cggtacaaat accttgccga cgccgacaag
     4141 aagaatacct ttgacgtgga cagatttttg actatcacgc gccggaaacg gcagcaagtg
     4201 gtaacgcagg atgaagtatt cgacctgtat gaaatcgacc tgtcggacga ggacgccgcc
     4261 gctgaataaa cagcggcttt tttcattcca acaacaaaat caaaaaatca ttatgagccg
     4321 gaaaccggca gaaagaggta aatttatggc attttttaat tccgcagtta ctactttgca
     4381 gactatcgtg atcggactgg gcggcgctct gtgcgtatgg ggcggcatca atctgttgga
     4441 gggatacggg caggacaatc cgggggcaaa atcgcagggt gtcaagcagc ttgtcgctgg
     4501 cggcggcgtg gccctgatcg gtgtcactct ggttcccctg ctgtccgggc tgctgggctg
     4561 atcctggcct ttgtccctgt ccaaaccctt aactaatcgc ctccgcgtcc tcccggccag
     4621 accgggaggg cgcgggaaag gaggtgctac ccgtgattag tgaaatcatt gaagaatgga
     4681 taaaaggcat cctcatggac ggtatcacgg gcaacctgtc cgggctgttc gatacggtaa
     4741 atgccaaagt cggagaaatc gccgccgacg tgggacgaac cccgcaggca tggaacagcg
     4801 gtattttcaa tatgctgcac agcctgtcgg aaaccgtgat cgtccccata gccggggcca
     4861 tactcgccct tgtcatgtgc tatgagctta tccagatgat aacggaaaag aacaatatgc
     4921 acgactttga cagctccatg ttcttccgct ggatattcaa atccgcgttt gcaatcctga
     4981 tcgtaacgaa cacatggaac atcgtcatgg gcgtattcga cgccacccaa agcgtcgtca
     5041 atcaaagcgc cggtgtgatt atcgggcaga catccattga ttttaacacc ctgataccag
     5101 accttgaaag ccaattggag gctatgagcg tgggcgctct tttggggctg tggttccaaa
     5161 cccttgttgt gggcctcacc atgaatatcc tttccatctg cattttcctt gtgacctatg
     5221 gccgcatggt ggaaatctat gttgtcacgt cgctggggcc tatccccctt gccacaatgg
     5281 gcaacgcgga atggcgcggc atgggccaag ggtatctgaa atccctgctg gcgctgggct
     5341 tccaagcctt tttaatcatg gttgtggtgg gtatctacgc ggtgctgata cagaatatcg
     5401 gttccgcttc cgacatatcc ggcgcaatct ggggctgtat gggctatacg gtgctgctgt
     5461 gcttctgcct gttcaagacc ggcagtatat caaaggccgt attcggggcg cattgatccc
     5521 aaaatccaag catacacagg aggaacttgt ttatttcaac gtacaacatc atttacgctg
     5581 acccgccgtg gcggtatgac tgcaaaaacg tacagggcgc agcggaaaat cactattcca
     5641 ccatgagcat tgacgagctg tgcgccctgc cggtggaacg gctggcgtcc aaagactgcc
     5701 tgctgttttt gtgggccaca ttccccatgc tgccggaagc tctgcggtta atcaaagcgt
     5761 ggggcttttc attcaagacc gtggcttttg tatggctgaa acagaaccgt aaaagcctta
     5821 catggtttta cgggctgggc cgctggacaa ggggaaacgc ggaaatctgc ctgctggcaa
     5881 cacacggcaa gccgaagcgt cgttctgcct ctgtccatca gtttattatc agcccgattg
     5941 aacaacacag caaaaagccg gatgtgaccc gtgaaaaaat cgtagagctg gcgggcgatt
     6001 tgccccgcgt ggagctgttt gccagacaga aaacccccgg ctgggacgtg tgggggaacg
     6061 aggtggaatg tgaccttatc ctgacgtgaa aggaggtgcc aaatggctta tgtaaccgtc
     6121 cccaaggact taacccatgt gaaaagcaag gttgtgtttg ggcttaccaa acggcaactg
     6181 atctgttttt ccggggcgct ggtgatcggc gtccccttat attttctcac ccgtgactat
     6241 cttaccaaca gcgcggcggc cctgctcatg gtatttgcca tgctgccggg ctttttgctt
     6301 gccatgtacg agcgtcacgg ccagcccctt gaagtggtga ttatgcagat catccagtgc
     6361 tgcttcatcc agccaaagga gcgtccctat cagaccgaca acacctacac cgcccttgtg
     6421 cggcaatacc agatggaaca ggaggtaaag gccattgtcc aaaaaggaaa tcccaagaga
     6481 aaccgaaaaa acaaagctga cccgcgccca gcgaaaagaa attgacgcgg taatccgtaa
     6541 atataagggc gacggcaggc cccacacggc gcagcagagc atcccctacg aggtcatgta
     6601 cccggacggc gtgtgccggg tatcgcccgg cgtcttttcc aagtgcattg agtttgcgga
     6661 catcagctat cagcttgccc agccggacac gcagacggct atctttgaaa aactgtgcga
     6721 cctgtataac tatgtggacg cctccattca tatccagttt tctttcctca atcggaaagt
     6781 tgacccggtg cagtacgcca agagctttga gatcgcgccg cagggggacg acttcgacga
     6841 catccgggcc gagtacaccg gcattctgca aaagcagctt gcaaacggca acaacggcat
     6901 ggtaaagacc aaatacctga cattcaccat cgaggccgaa agcgtgaaag cggcgcgagc
     6961 cagattgaag cgcatcggct ttgacctgtt aggctatttc aagagcatgg gggccgtagc
     7021 ccatgtgatg gacggctggg aacggctgaa cctgctgcat ggcgtgtacc acccggacgg
     7081 cgagatattc aattttgact ggaagtggct ggccccgtcc ggcctctcca ccaaggattt
     7141 tattgccccg tcctccctgt gcttcggcaa tgcaaagaca ttcggcatgg gcggcaaata
     7201 cggcgcggta agtttcctgc aaatcctgtc cccggagctg tcggacgata tgctggccga
     7261 cttcctcaat acggaaagcg gtgttttagt caatctccat gtgcaggcca ttgaacagac
     7321 caaggcgatc aagaccatca agcgcaaaat taccgacctt gacgctatga agattgcgga
     7381 gcagaaaaag gccgtccgca gcggttacga tatggacatt cttcccagcg accttgccac
     7441 ctacggcgag gacgccaaga agctgctgac aaagttgcag acccgcaatg aacggctgtt
     7501 ccagttgacg ttccttgtcc tcaacgtggc cgacaccaag caaaagctga ataacgacgt
     7561 gttccaagcc gcaggcgtgg cccaaaagca taactgtccc cttgtccggc tggactacca
     7621 gcaggaacag ggccttgcaa gcagcctgcc gctgggcgtc aatcagatca agatacagcg
     7681 cagccttacg acttccagcg tggccgtgtt cgtccccttt gtgacgcagg agctttttca
     7741 gggcggcgcg gccatgtatt acggcatcaa cgccaagtcc cgcaacatga ttatgctgga
     7801 caggaagcag gcccgttgcc ccaatgcctt gaagctcggc acccccggca gcggcaaatc
     7861 catgagctgt aaatccgaga tcgtcagtgt gttcttaacg acgcctgacg atatttttat
     7921 ttcagacccg gaggccgaat attaccccct tgtcaaacgg ctccacggac aggtaatccg
     7981 gctgtcgcct accagcaagg actttgtgaa cccgctggac atcaacctga attattcgga
     8041 ggacgataac ccgctggccc tgaaatccga ctttgtgctg tcgttctgtg agcttgtcat
     8101 gggcggcaag aacgggctgg aagccattga aaagaccgtg atagaccggg ctgtgcgcgt
     8161 gatctaccgg ccctatctgg cagacccccg cccggagaat atgccgatcc tgtccgacct
     8221 ccacaaagcg ttgttagatc agcatgtccc ggaggctgac cgggtggcgc aggcccttga
     8281 cctgtatgtg tccggctccc tgaacgtatt taaccaccgt accaacgtgg acatcggcaa
     8341 ccggcttgtg tcctttgaca ttaaggagct gggcaagcag ctcaaaaagc tggggatgct
     8401 cattgtccaa gaccagatat gggggcgcgt cacggccaac cgaagccaag gaaaggccac
     8461 atggtatttt gccgacgagt tccatttgct tttgaaagag gaacagacgg cggcctattc
     8521 tgcggagatt tggaagcggt ttaggaaatg gggcggcatt ccaacaggtg ccacccagaa
     8581 cgtcaaagac ctgctttcct ccccggaaat tgaaaatatc cttgaaaaca gcgacttcat
     8641 tacgctgctc aatcaggcgt ccggggatag aaaaatcctt gcggaacgct tgaatttgtc
     8701 caccgaacag cagaagtaca tcgacaattc cgaacccggc gagggccttt tgatctttga
     8761 aaacgtggtg ctgcccttta ccaaccccat cccgcacaac acccagcttt acaagattat
     8821 gacgacccgc ttaaacgagg tggcgggagt atgacccggc gacgccacaa aggaggtgaa
     8881 ccaccatgaa agagctgaaa gccaaggcga aagtgacgca ggccatgacc cgcgacgggc
     8941 tgacgctgga aaatcaggcc accggcgagg tggagaacat ttccagccgg gaggccgaac
     9001 aggatttgtc cgcgccgggg ccgggcggca ccgccgataa gctgctggaa cgggccgacg
     9061 ccatccatga cggccataag gccaagaaag ccgcgaagca ggccggggct gtggccgccg
     9121 agggggacgc tgccctgcac cggccatccg cccggctcca actgtcggag gaagaacggg
     9181 ccgacccgga tttacagccc tatatccgaa aatcggacaa acgggccgat aagctggata
     9241 aggcccgcgc cgccatcccc aagaagcgcg tcccggtcaa ggaaaccgtc tttgacgagg
     9301 caagcggcaa agcaaagacc gtcctgcact ttgacaaaca ggacaagggg cctccctccc
     9361 tgaaacccaa tccggcaggc cgtcctgttt ccgaggtttt tctattcggc cacgggaaaa
     9421 tccatgaagt cgagcatgaa aacgtgggtg tggagggcgg ccataagggg gaggaacttg
     9481 ccgagcggca ggccggaaaa gccatccgca gcaccatccg gcaccacagg ctgaaaccct
     9541 actgggacgc ggaaaaggcc gagcgcaggc tattgtctgc caacgcggag tatttctacc
     9601 agaaatcttt gcgggataac ccggagatcg cacaggcggc cagcaacccc atttcccggt
     9661 tctggcagaa acagcagatc aagcgccagt acgccaaggc cgcccggaca gcgggccaga
     9721 ccgcaggcgc ggcggcacag ggcgcggcca agacagccgg ggcctccacg aaagcggcca
     9781 aggccgcagc caaagaaagt gaacgggcgg cctcctttgt ggcccgccac tggaaagggg
     9841 cgctggccgt ccttgtgttg gggcttttga tgctgcttat catcggcggc ttacagtcct
     9901 gcaccgccat gttcggcagc gccggaagcg gcatcacggc gtcctcttac ttttccgagg
     9961 atagcgatat gttggccgcc gaggacgcct acgcggagct ggaagccgag ctgcaagact
    10021 atctggacaa ctacgaggcc acccatgact atgacgaata ccattttgac cttgacgaga
    10081 tcagccatga cccctatgtg ctgatttcca ttctgtcggc gctccatgac gggatattta
    10141 ccatcgggga ggtacagggt gatttgtcca tgctctttga caagcaatat atcctgacag
    10201 aaaacgtcgt ggtagaaacc cgttaccgca ccgaaaccga tacatggacg gacgcggagg
    10261 gcaacaccca tacagacacc taccaagtgc cgtatgacta ttacatctgc tacgtcacgc
    10321 tggaaaactt cgacctgtcc catgtgccag tctatatcat ggacgaggaa acgctaagtt
    10381 tctattccct gtatatgtcc acgctaggaa accggcctga tctgttttcc ggcagccagt
    10441 accccaacgc ctccaccctg acgccgccga cctactacga cgtacccccg gaggctttgg
    10501 aggatgccac ctttgccgcc atgctcaaag aggcggaaaa atatatcggt tatccctatg
    10561 tgtggggcgg cagctctccc agcaccagct ttgattgcag cggcttcatt tcgtgggtaa
    10621 tcaatcatag tggatggaac gtgggacggc tgggggcgca gggcctatat aacatctgca
    10681 cccctgtttc cagttcgcag gccaagcccg gcgaccttgt atttttcaag ggaacctacg
    10741 acacccccgg cgtgtcccac gtcggcctgt atgtgggcaa caatgtgatg ctgcattgcg
    10801 ggaacccgat ttcctacacg aaccttactt caaactactg gcaatcccat ttttacagtt
    10861 acgggcgttt accttaacgc cagaaaggag ctttcaatta tggcaaccaa acttgaccgc
    10921 atcgaaaagg acatccagaa aaccaagtct aagatcgcgg agtttcagaa acagcttcgg
    10981 gagctggaaa cgcagaaaac cgaacaggag aatttgcaga tcatccagct tgtgcgcggc
    11041 atgaacatga agccggagga atttgccgcg ttcttacgca gcggcgcaat gcaggccgcc
    11101 cctgccgcaa ccccttacca tgaacaggag gacaatgccc atgaagaata agaccagacg
    11161 gatttcccgt attctccccg cacttctggc cgtgatgctc tgcgtcacgg cctttcccgt
    11221 taccgccctt gcaggcggca atgacccggc accggccccg ctgccggagg ctacaaccga
    11281 acccgctacg ggcggtttgg agcctgaaac agacgaaacc ggcaccgcca cggacgggac
    11341 agaaaccgag gccgaaaaag ataccggccc tctgaccggc aaggacatca ccgacctgtt
    11401 ttccgcgctg ttcggttcca aggtgagcat tgccgccacg gacgacggca tccagatcac
    11461 caccggcacc gacaaaaaag aacctgaaca gaccggcacc gtcaccacca acggcggcag
    11521 gctgaatgtc cgcaccggcg cggggcttga caagaccgcg ttcacccagc ttcccaatgg
    11581 gacgacggtt gaggtagtcg gcacagacgg cgactggatt aaaattctct tgccggagcg
    11641 catcggctat gtccattccg actatatgac cgtcagcgaa aaggaagtag cggctaccgg
    11701 cgagggcggt ttttccctct ccattgaccc ggaggaaatt gcttctctgc tggaactgtt
    11761 caatggcggc ggggccagcg ccgccctgtc cccggacggg aacctgtcac tgattgacga
    11821 catcggcagc gccgcgaaaa atggcaagca gtttatcacc gtggaaacca aaaacggcaa
    11881 tgtgttttat ctgattattg accgggacga cgagggaaaa gaaactgtcc atttcttaaa
    11941 tcaggtggat gaagccgatc tgctgacgct gatggaggac ggggaaaccg tcacccccgc
    12001 tgctgtctgc tcctgtacca cgaaatgcaa ggccggggct gtgaacacga attgcccggt
    12061 atgtaaaacc aacctgaccg agtgcagcgg cccggagccg caggaacccc agccggagga
    12121 acccgaagcc ccggaggaag aacccaaggg cggcgcgggc ggcctgatcg tgttcctgct
    12181 ggtggcgctg gcgggcggcg gtgcggccct ttactatttc aagttcaaaa agcccaaggc
    12241 tgaaaccacc ggcagcgacg atttgggcga gtatgatttt ggggaggacg aggatttgga
    12301 ggacgaggaa cccgaaaccg agtttgaccc ggaagctgat tttgtgagtg aacaggagga
    12361 cgaggaatga catataaact tgtaatcgcg gaaaaaccca gcgtggcccg cagcattgcg
    12421 ggcgtgatcg gggccacgga gaaacacgac ggctatttgg aggggaacgg ctatctggtg
    12481 agctggtgca tcggacatct ggtgtccttt gccgacgccg gacgctatga cgagcgtttc
    12541 aaaaaatggc gctatgagga tttgcccatt ctcccggaaa catggcagta catcgtcccc
    12601 gacgacaaga aacagcagtt tgacgttctc tgttcgctga tgcagcgccc cgacgtgacc
    12661 ggccttgtgt gcgccaccga cgccgggcgc gagggggaat tgattttccg tttcgtctac
    12721 cagatggcgg gatgccaaaa gccctttgag cgcctttgga tttcctctat ggaggacagt
    12781 gctattaagg acggctttgc ccacctgaaa ccgggcggcg actatgatcc gctgtatcaa
    12841 tcggccctgt gccgggccaa ggccgactgg ctgatcggca ttaacgccac ccggcttttt
    12901 tccgtcctgt accacaagaa cctgactgtg ggccgcgtcc agacgccgac cttaaaaatg
    12961 ctggtggaca gggacgccaa gattaccgat ttcaagaaag agaaatatca catcgtccat
    13021 atcacggcgg gcggcgcgga cgcggtaagc agccgctttt ccgacgctgc cgaggcaaac
    13081 accgtcaagg cggcttgtgc aaaagcgcag gccgtttgcg tttccgtgac gcgggagaaa
    13141 aagacggaac agccgcccaa gctctatgac cttaccacct tgcagcggga ggctaaccgg
    13201 cttttcggct ataccgccaa gcagaccctt gactatgccc aggcactgta tctaaagaag
    13261 ctgctgacct atccgagaac ggatagtcaa tatcttaccg acgatatgct gcccgccgtg
    13321 gaaagccttg tgtccggcct gtgggagctg gtgccgtttg ccaagggcct gaacctttcc
    13381 ccgcagtttg accgcatcct gaacagcaaa aaggtgtccg accaccacgc cattatcccc
    13441 accgctgaat ttgtgaagca gggctttggc actctggccg agagtgaaaa aaagctgctg
    13501 tccctgatct gctgcaagct cttatgtgcc gtggccgggc cgcatatcta tgaggccgtc
    13561 accgccacat ttacctgtgc cgggcaggag tttaccgcca agggcaagac cgtcctttcc
    13621 cccggctgga aagagattga acgccggttc cgttcttcct taaagaccga cgccgacgag
    13681 gacgccgagg cggtgcggga gctgccggag ctttgcgagg gccagacctt tgcagacgtg
    13741 gccgcctctg tcaccgagca tttcaccacg ccgcccaagc cctacaccga agatacgctt
    13801 ttgtccgcta tggaacgggc cggggccgag gatatgccgg aggatgccga gcgcaaggga
    13861 ttaggcacac cggccacccg cgccgccatt ctggaaaagc tggtgcagat gggctttgtc
    13921 cagagaaaag gcaagcagct cattcccacc aaggacggca tcaatctggc tgtggtgctg
    13981 ccggaggcgc ttacttctcc ccagcttact gccgaatggg aaaaccggct gaccgagatc
    14041 gccaaggggc aggccgatcc tgacgaattt atggacggca tcgagacgca ggcgcgggag
    14101 ctggtgcaga cctattcctg tatcagtgag gaaaagcaga aattgtttca ggccgagcgt
    14161 gttcctatcg ggacgtgtcc ccgctgtggt gaggctgtct atgagggcaa gaaaaactac
    14221 tactgcggaa accgggcctg ccagttcgtc atgtggaaga atgaccgatt ttttgaggaa
    14281 cgcaagaaag cgttcacccc gaagatcgcc gctgcgctgc tcaaaaccgg caaagtcaag
    14341 gtaaagggcc tctattccgt aaagaccggc aaaacctacg acgggacggt gcttttggct
    14401 gataccgggg gcaagtacgt caactaccgc attgaacaca ggagctaaag gacagtaaca
    14461 cagcaagcat agggagtgtg gctacactcc cggtaaaatc ccccggccgc gtccctgccg
    14521 ggccggggat ttttgcttgt tggggaagtc cccaaccccc tattttttga aacagaacag
    14581 agaaaggagt gaccgcgtga acgaagtatt ttctatccaa gtccataacc ggcagttttt
    14641 ggaacagggc aaacaaggcg tctggctgga tttgcccacc acaaccgaaa cgctgcaagc
    14701 cgccctgcgg gatgttggca ttactgccga caatccgcag gattttttta tcaacgggta
    14761 ttcctgcccg gaggacagac accttgccat tccctatgac atggtgctgg ccgccgacgt
    14821 ggacgagctg aatttccttg ccgcccggct gggccagctt gacgccgccg agatcgcaga
    14881 gctgaacgcc gccctgcaaa atccccgtgg cggctttgag aatatcggcc agatcatcga
    14941 ctacaccgaa aatgtggatt actatgtgca tcttcccgac gttagggggg atggacagtt
    15001 gggcgactac tacctgaacc gttccggcat ggtggatatg ccggaggaat ggaaagccgg
    15061 gattgatacg gcgcagtttg gacgccacat tgcccagcag gaacaaggcg tttttaccca
    15121 gtacggctat ctggtgagaa gcggcgacga atggcagcgc gtccatgagg gccagccggt
    15181 gccggaggaa taccgggtga tgcactaccc ccagccggaa gctgaccggg aggaaccgca
    15241 ggcccagcag ccggaggcat ccgaaagccc cgacaaagcg ccgcccccgg ttatcccgat
    15301 catgctggac ggcatgaaca gcaaagaacg catgaaagtg attactgacc gtctggaaac
    15361 cggcgtacag gagctttttg aaagtagccg ctatatggct tacttatccg ctatgtccaa
    15421 gatgcacgat tacagtctga acaatacgct gctgatcgcc atgcagggcg gttcgattgt
    15481 ggcgggctat aacaggtggc aggatgaatt tgaccgccat gtgaagcggg gcgagaaagg
    15541 cattaagata ctggccccgg ccccgttcaa ggttaagcag cagatggaga aaaccgaccc
    15601 ggccacccag cagcccgtga tcggcgcgga cggcaagccc gtgaccgaag aacaggaagt
    15661 gacggttccg gcctttaagg tggtgacagt ctttgacatc agccagaccg agggcaagga
    15721 ttttcccatg ccctatatca gtgaacttac cggcgacgtg cagcagtatc aggatttctt
    15781 tgccgcgctg gaacggacat caccctatcc cataagcatt gagccgattt cagacggggc
    15841 caagggccgc tgcttctacg caaaacagcg cattgccatc aacgagggca tgagcgaatt
    15901 gcagacccta aagaccgcca tccatgagat tgcccatgcc aagctccacg ccattgaccg
    15961 ggaggccccc gccgaggaac aggcggcccg gccagaccgc agcacccgcg aggtacaggc
    16021 cgaaagcgtg gcctataccg tctgccagta ttacgggctg gacacgtcgg actattcttt
    16081 tggctatgtg gccgattgga gcagcggcag ggagttatcc gagctgaaag cctcccttga
    16141 aaccatccgg gccacggcca gcgaattgat aaccgagatc gacggccatt ttgcccagct
    16201 tcagcaggag cgcgaggccc ggcaggaaca ggaggccgtc acggttgacg ttaccccgga
    16261 ggcagcggcc ccggcgcagg ccgaggaaga acaggccccg gcccttgatc cggcagccga
    16321 gccgcttgtg actgtgctat ggagcgaaag cccccagcta aaggacggcc agcaaatgcc
    16381 gttgcatgag gccgacgcgc tgtttgcccg tctggatgca gcatatccgg cagaggcagg
    16441 ctatgacaaa accgcgttcc gcattgactg tatctttcag ggcgagccgg acagctacga
    16501 ggggcggcag gattttggag atagggacgg ttccctgatc gaacatatcc agagctacca
    16561 ccaattttac gcgcaggacg aaaactggaa aaagcatgta atcgctacaa ccggcataga
    16621 gggctgggag caggacaagg cccatcggga tatgctgtta ggcgagtttg tcccctatat
    16681 gaagctgcat tgcagccttg cccaaatgga acagacggcg cagggccgct tacagtccgg
    16741 ggaaaccctg acgccggagg aaacggccta tttgggggcg cttctctctt atgtgcagga
    16801 gtgccgcccc atgctcaatc agggccagta tcagttgccg gagccgccga aactggctga
    16861 cttcgaccag agcttgcagg actacaaagc acaggtacag gccgagatcg cgcaggaggc
    16921 cgccgcagcc ggtatgaccg tggaggaata cgcggcggct ggctatgaag caccccaaca
    16981 ggacaccttt tccatctacc agcttcgagg cggggaggaa acccgcgact atcggtttga
    17041 gccatacgag cgtttacagg ccgcagggct ggccgtggac agtgccaact atgaccttgt
    17101 ttatacggca ccgctggata aaagcacgtc tttggaggat atttaccgca cattcaacat
    17161 cgaccacccg gcagatttta ggggacacag cctttccgtt tccgacgtgg tggtgctgca
    17221 ccagaatgga caggacaccg cccactatgt agacagcttc ggctatatgg aagtgccgga
    17281 gtttttgcgg gaaaatcccc tgcgtaccgc cgaactgtct acggagcaga acgaaaacat
    17341 gattgacggc attatcaaca atacgccgcc cgaaccgcag ccggaggaac ccgaacagct
    17401 atcttttgag gatgtggcag ttgcttccgg ccagacacag gaggaacccc cggaggctgc
    17461 gcccccgcaa acggctgtcc gctattatcc catcaatgag ggagccgccc gccgcgccaa
    17521 ggaagccatg agcttttctg actaccggcc cggcagcgcc acggcggaat accggcacta
    17581 tgtcgatcag gccgtggaaa ttgcggagcg ccagaaaaag cgtgtggagc cagagtatca
    17641 cgaaaagata gacagcctcc ttgacaccta cgcccgcaag ctggccgaga acatgaataa
    17701 gggctatgag attaccgccc gcgtcccctc tgtcctgatt gccgggccgt ccaatttccc
    17761 ggtacgggcg aaagaaaagc agaacgccgc cagtgaccgc aacatggagg aatttcagta
    17821 cattcagggc ttgcttgaca aaatccgcag caccggcatg ggtggtatca gcgccgacga
    17881 tccgcaggcc gtttccaagc tggaaaagaa actggaaaag ctggaagcgt cgcaggagtt
    17941 gatgaaggcc gtcaatgcct actaccgcaa gcatgggacg ctggacggat gcccccatct
    18001 gatcgaaaga ggcattgaaa acctgaaagc ggatatggcg tcgggctggc actatgagaa
    18061 aaaaccgttc cagtcctggc agctctccaa caataacgcc gagatacgcc ggttaaaggg
    18121 ccgcattgag gaattgaccc gccaaaagga ggcggcctat gtgggatggg agtttgacgg
    18181 cggcactgtg gagatcaacc gggtggccaa ccgcctgcaa atcttctttg aggggaagcc
    18241 ggatgctgct gtacgcgacg agctgaaaag caacggtttc cgctggtcgc ccaaggccgg
    18301 ggcatggcag cggcagttaa acgacaccac aatccgcgtc gctgaccgta tcaagtgcat
    18361 ccagcccctt tccggcgaaa agcccagcgc cttacagctt gcggcccgca gggagaaaga
    18421 aaagccctct atccgggcgc agctcaacgc ggccaagacc gaacaggcca agcagccacc
    18481 ggcgcgggaa aaatcaaagg gattggaggt agagtaaatg cagaagtttg aaaatgtgga
    18541 cgttctggcc gcgctggaac agatcatgcg gcagaacacc gcgttttatc aaagtgactt
    18601 tggcattgac aaagacatta tcaggcggga tgccgccagc gatcaggccg cagacaagac
    18661 cctgctctgg atgtcccggc cctccgggac gtactgtttc cgggaacgtg atgttttcct
    18721 gaaagacacc cgacagtaca acacatggaa attttacggg gagcagaccc gtgacaagat
    18781 actggcctac gcggtggagc tgaccggcac acagggcggc actatccggg gcaatctcta
    18841 tgagctggac tatccgcagc atttccggca cgtcattgaa accgcccagc cggtgagtgt
    18901 gaaccggctc ttttatgagc atggcacccg tgacatcccg gagagccagc gttttgacgg
    18961 aagccctgac cgggtattgg gaaacttttt gtactatgag gcccagcccc atgacccggc
    19021 tgtgctgcag gaggcgctac ggacggagca gcacagccgg gggcgggccg tccccggcga
    19081 tttcaaagtc cacgtcaccg ctttgcatga cagccggatt gaaaccgagg cccggcgtat
    19141 tgtggacagc ctgaaagatc tgtccgcgcc taacagcccc aataaaacgc atttcatggt
    19201 ggagatctcc ccgcactttg cggcgattgc ttccaccaag gataatgacc ggctctttgc
    19261 catgctgccc tataaatccc tgtgttttac cgggatgaaa ggcaggcatg gcgtgtatgc
    19321 cgtgattaac cgggacgagc gccgggatgt gagtattcgc aggccccggc cctctatccg
    19381 caagcagcta tccgacagca aacaggccgc cagcccaaaa aaggcggcgg ccagaaccaa
    19441 aaagaatgaa ttggaggtat aaggaatgat gcactttacc gtggaggaag aaaacctgat
    19501 ctgtatgtac cacaatgcag accggcgcag aacgataaac aggctcaccg ccgtcatgcc
    19561 ggttatggat ggggatatgc gggcgcaggc ccagcagacc ctttccaagc tggaacgcat
    19621 gacggatgcc gactatgacg gccagaagtt ccacttcaca gacgaataac gaacagcaga
    19681 cgccgggcgc ggcggccatg tggtcgcttg cgtccggcgt cttttctttt tgcctattcc
    19741 tacgcattta gaacccggta ttgtcgggga taggatgaag tattcgcttg cccctgcaaa
    19801 catgcgggag aagccttgca gcgggcggtt ttcaatccct taaatgcgta ggttgcagct
    19861 ataattagac ccctgaaaca gatatagccg cgcagcgggt gtatctgttt caggggtgtg
    19921 caggtgatag ccgcaaagcg gcgtaagagg gtgcagccct cttgccgtct atctctgttc
    19981 cagcgggaag ctcggcaatg cttccagcag tttcagggaa atgcgctgcc gtatatcttc
    20041 gtcaatgact ttcttctttt tgccgtttgc ctgtctgatc tccaccgtgg aaagctcgtt
    20101 gatgtagtca gcataatggg ccaacacttt ttccgtggcc cacctctcac cggcaacggc
    20161 ggctttgatc gtttcatagt ccagcagctt ttcttgtccg tccatcctga tacccccgtc
    20221 agactgattt tttctatgat accatattcg gaagcatgga accagagaaa acggcgcttt
    20281 tctgctggta aattctacgc atttagaaca gcacttcggc ggggatagga taaaacaccc
    20341 acataccccg ctgaccatgc cggaaaagcc ttgaaatata agggctttta cagctctaag
    20401 tgcgtaggtt tccagtatct tttccgctgg cgctcggcct ctttgcggcg gcgcatccgt
    20461 ttggagcagg ccgcgcagta tttggcccgg ttagacttcg gcgtgaacgt ggccccgcac
    20521 tcacagcagc gtttcacttc gtcccggtct ttggtgatct cggcatacag ggccgcatcc
    20581 agcgggagga cagcggcctt aaaccagcgg cacagaagcg aataggaaat gctctgtacg
    20641 caaatacatt cttcgccgtc gtccagcaac aggcagttgc cgtcacaata gttgcagcac
    20701 tcatgcgtca gcttccgggc cttgcgatat tgagggtaat tcattcgtgg aatactcata
    20761 gctcttgcgt ccattccttt cccggcgtca tacgcaaaat gccgtccaca ttctgcttga
    20821 tgatgccgta ttcctgcatc tgctttttcg cttcgccgta cttctcatac agccgttcct
    20881 tttcctcggc caatcgcttg tactcggctt tcagggcgta cagatcgggg agctttttca
    20941 caccctgtcc ctttagggcc tttgccgcag cttcatacaa aatcaacgtg ctttcatgct
    21001 cacgccggaa ttttgcctta tccgctgcat tgcggtattc catagccacg ggccagagct
    21061 gcttgtaggt agaaatattc tttatcagca ccgccatatc cgcaagccgg tgttccatag
    21121 ctttgagggt agcggcggcc tcgtcgctgg cggcggtgat ctcggccact ttgctttcca
    21181 aatccgggta ggtgtctatc ccatgttcag tcaggaaatt caaagtcttt gcggcctgct
    21241 tcaaattgtg gagcttcgcc cacctctcat agcctgccga ctgctgggcc ttaatgttgt
    21301 tttccagatc aatccgcaaa gaaatcccct tgcgctcttt gggcgctctg gtgataacgc
    21361 ggcctttgat acgctctttg atggcttcct cggtgtaggc ttcccccaat gtcttgcagc
    21421 gggtaaagcg ttcctgtccg ggagcgcgga aagaaataaa ctttcccggc ttgatctcat
    21481 agccctgcgc ctgcatgagc cgcaggaaat catcaaaatc ttttgcctgc gggatagcgg
    21541 cgtcaatggc tgctttgagc ttcgctttcc agctcgtccc tttccgctgg gcgtcccact
    21601 cggcatagct cttgccctta ctctggccgg gcttcaccac ggacaatccg ttttccttgc
    21661 acagcctgtc gctggtgcgc cggatatagg catagctctg tttgttggaa atgtacttgc
    21721 gctgatttac catatccacg gcacagaaaa taatgtgatt gtggacgtgg cccttatcaa
    21781 tatgggtagt cagcacatag ggatatttcc cttgcagcac ttcctcggca agctgcttcc
    21841 cgatctcatg ggcctgttcc ggcgtggctt cgccgggggc aaaggattgt atcaggtggt
    21901 ggcccagatt attgcccttt tggtatgcct gcgccagcag catttcaaat tcaatgtccg
    21961 ctgtttcata agagcaggca aaggaggcca ccagcagctt gccgtcagtt ttgtccgggt
    22021 tctcgatgta gtcaagggct tttttcagcg ttgacttgat aggatgtatc tttgtaactg
    22081 ccatatctgc gccagcgccc cctttatatc ctcgatgtcc tgtgcgtaca ccggccccat
    22141 accgttcagc ctctttgcaa tctgattgac gttgacgccg atcttctgta tctcggcggt
    22201 ctgcgcccgg atgtcgctgg tgtccatgtt gacgatatag ccgtcaatga gcatcttccg
    22261 ggcgtaggct gaaaagttct tcgtatgcag cagcgccatt ttctgttcaa tcatagcccg
    22321 ttcctccggc gtcacaggga cgcgcagcac gatttttcgc tttctgtttg ccatgcttca
    22381 ccgtcctttc cattcagggg tttggggatt tccccaacaa gcaaaacgga cgcggcccgg
    22441 cagggacggg gcaggccgtt tttccgggag tggctacact ccctatgctt gctacgttac
    22501 tgtttctcca ctaacaagac gtttccaaag ccccaaacta cccgcaaaat agccctctgg
    22561 aaagaaaaaa gtgcaaaaaa atagaagcta cgctgtgcag ctcccgctaa aagtaaaaca
    22621 gaggatgcca gttacacatc ctccgtttca ttcttcttcg gcttttcaat tagtatggcg
    22681 ctgtcaatcg cgccctcgat gatcggcagg tattcttcgg ggcagagttt cagcttgtgg
    22741 ctgacccttt gccgcagttc gctttcctcc cgcatgatct ccgggttaaa gtagcgttcc
    22801 acaggaagcc cgcaggcttt aataagctgt atgacaaccg gcagactggg aatggcccgt
    22861 cgttttcgat gttggcaaga tagcgccagt caatatttat tttctctgcc attgctttgc
    22921 gcgaaacgcg ctttgcttgc cgggccgctt tcacatccgc gccgaaagtt tcaaagccgg
    22981 gacaatcttc aatattcgcc atatcgcacc tcccacttac attgtatatt tcatactctg
    23041 cccgtggaat gttggtatat gcacctttct taaagtttat atttcacatt ttgtttcttt
    23101 tattcttcga gcaaaagaat tataatgtac cctgtggagg tgtactatgg actacatgac
    23161 gttgaaagag gcaggcgaga aatggggtgt gcccccacga tggataaact actattgtgc
    23221 tgcgggacgc atccccggcg ctgtaaagat ggcgacgatc tggctcattc ccaaaactgc
    23281 ggaaaagccg attgacaggc gtacaaagaa aggaaaggcg gttactgaat agtataatga
    23341 aaccggcgca ttttggatat ggttttgaag agagagaaag catggtattt tgtcacggaa
    23401 aaactataag atgatagatg gcaggctgct ccagaccgat aaaaagtatt ctcatctgaa
    23461 acagaaagaa aagatttaca catggatgta tgaagaagcg aaactttatc atgacagaaa
    23521 tggaaaatgc ccgaaacaaa gacgaggaag ctgctgctgt atcagccgta tatggtagaa
    23581 ttgaaaaggc cggcatctgg attctttatg gtgaagtctc cagacattgg ataactgctg
    23641 gtctaatgcg cctttgagta tggggtgatt gattttaata ccggggaggt acggcttttt
    23701 gaggaaaata ttctgggatt tacatttggc gattattaca tttcctgtaa ctgcaaggac
    23761 acggatgatg aagatatgag gaatatagac ttgctgattt tctactgtct tgaacggtat
    23821 taggactgaa tctgctgcgc ggagtgcggc aagagcgacc ggagggagta cacacaggcc
    23881 ctgcctgtgt gaaaagccat accgcaaggt gcattcgcaa aaaagaggcc gcgcattttg
    23941 ctgaggcttg gggtgtcccc aacaagcaaa acgagaacgc cgcaggcggg caagtggtgg
    24001 atcagaatat ccgtaaagga tattctgatc cattgcttgc cagtattatc gggatgtttt
    24061 gacaaccgct gtaatcgaaa catcccaaac attaagaagg tgttaattat tattatcttg
    24121 atttaattcg tttaaaccaa taatatagat acatacacca tgaaaagaag cgagtatccc
    24181 aatgacggat gattaaaatc cgaaaagaaa tcgctttgaa actacaggga aactacagac
    24241 tgttatgtta tcttcttaaa atggagggat ttttatgtcg atacgaattc tacttgtcga
    24301 ggatgatgat catatctgta atacagtaag ggcgtttctg gctgaggcag gatatcaggt
    24361 ggatgcctgc acagatggaa atgaggcata caccaagttt tacgaaaaca cttatcaact
    24421 ggttattctt gatattatgc tgcccggtat gaacgggcat gaacttttgc gtgaatttcg
    24481 tgcgaaaaat gatactccca ttctgatgat gacagccctg tcggatgacg aaaaccaaat
    24541 ccgggcgttt gatgcagagg cagacgacta tgtaacaaag ccattcaaga tgcagatttt
    24601 actaaagcgg gtggaagccc tgctgcggcg cagcggtgcg ctggcaaagg aaatccgtgt
    24661 cggcaggctg acacttctgc cggaggattt cacggtactt tgtgacggta cagagctgcc
    24721 cctgacacga aaagaatttg aaatcctttt gctgctggtg cagaacaaag gcagaacctt
    24781 aacgcatgaa atcattttgt cacgtatatg gggatatgac tttgagggtg atggcagcac
    24841 agtccacact catatcaaaa atttgcgggc caagctgccg gaaaatatca tcaaaaccat
    24901 tcgcggtgta ggataccgat tggaggaatc ataataatgg aaagaaaagg gattttcatt
    24961 aaggtttttt cctatacgat cattgtcctg ctactgcttg tcggtgtaac agcaacactg
    25021 tttgcacagc aatttgtgtc ttatttcaga gtgatggaat tacagcaaac agtaaaatcc
    25081 tatcagccat tggtggaact gattcagaat agcgataggc ttgatattca agaggtggca
    25141 gggctgtttc actacaataa ccaatccttt gagttttata ttgaagataa agagggaagc
    25201 gtactctatg ccacaccaaa tgccaataca tcaaatagtt ttagacccaa ctttctttat
    25261 gtggtacata gagatgataa tatttcgatt gttgctcaaa gcaaggcagg tgtgggattg
    25321 ctttatcaag ggctgacaat tcggggaatt gttatgattg cgataatggt tgtattcagc
    25381 cttttatgcg cgtatatctt tgcgcggcaa atgacaacgc cgatcaaagc cttagcggac
    25441 agtgcgaata aaatggcaaa cctgaaagat gtaccgccgc cgctggagcg aaaggatgag
    25501 cttggcgcac tggctcatga tatgcattcc atgtatgtca ggctgaaaga aaccatcgca
    25561 aggctggagg atgaaatcgc aagggaacat gagttggagg aaacacagcg atatttcttt
    25621 gcggcagctt ctcatgagct aaaaacgccc atcgcggcta caagcgttct gttggaggga
    25681 atgcttgaaa atatcggtga ctacaaagat cattctaagt atctgcgcga atgcatcaaa
    25741 atgatggata ggcagggcaa aatcatttcc gaaatactgg agcttgtcag cctgaatgat
    25801 gggagaatcg tacccatagc tgaaccgttg gacatagggc gcacggttgc cgagttgctg
    25861 cccgattttc aaaccttggc agaggcaaac aaccagcggt tcgtcacaga tattccagcc
    25921 gggcaaattg tcctgtccga tccgaggctg ctccaaaagg cactatccaa tgtcatattg
    25981 aatgcagttc agaacacgcc gcagggaggc gaggtacgga tatggagtga gcctggtgct
    26041 gaaaaatgcc gcctttttgt tttgaacatg ggcgttcaca ttgatgatac tgcgcttcca
    26101 aggctgttca ccccattcta tcgcattgat caggcgcgaa gcagaaaaag tgggcgaagc
    26161 agaaaaagtg ggcgaagcgg tttaggactt gccatcgtac aaaaaacgct ggatgccatg
    26221 agcctccagt atgcgctgga aaacacctcg gatggcgttt tgttctggct ggatttaccg
    26281 ctcacatcaa cattgtaaat atttaaaact taaatgattt tgggctcttt gtcaaatagg
    26341 actgatagag tgagataaga ac
//
LOCUS       DADVXE010000220        12678 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.guided.075, whole genome shotgun sequence.
ACCESSION   DADVXE010000220 DADVXE010000000
VERSION     DADVXE010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12678
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.guided.075"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            complement(134..577)
                     /locus_tag="KB913_003023"
     CDS             complement(134..577)
                     /locus_tag="KB913_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBB6821285.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="KB913_003024"
     CDS             complement(795..2135)
                     /locus_tag="KB913_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6821286.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="KB913_003025"
     CDS             2404..3300
                     /locus_tag="KB913_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBB6821287.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="KB913_003026"
     CDS             complement(3450..4391)
                     /locus_tag="KB913_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBB6821288.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="KB913_003027"
     CDS             4517..5638
                     /locus_tag="KB913_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6821289.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="KB913_003028"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="KB913_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBB6821290.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="KB913_003029"
     CDS             7426..7992
                     /locus_tag="KB913_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6821291.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="KB913_003030"
     CDS             8203..9264
                     /locus_tag="KB913_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6821292.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="KB913_003031"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="KB913_003031"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBB6821293.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="KB913_003032"
     CDS             10177..12159
                     /locus_tag="KB913_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6821294.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="KB913_003033"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="KB913_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBB6821295.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
BASE COUNT         4181 a         2321 c         2630 g         3546 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatc
//
LOCUS       DADVXE010000221         9859 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.guided.089, whole genome shotgun sequence.
ACCESSION   DADVXE010000221 DADVXE010000000
VERSION     DADVXE010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.guided.089"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            <1..203
                     /locus_tag="KB913_003034"
     CDS             <1..203
                     /locus_tag="KB913_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821296.1"
                     /translation="KMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNK
                     PSDNFSFRFAFRAKSKKTSPIK"
     gene            363..2249
                     /locus_tag="KB913_003035"
     CDS             363..2249
                     /locus_tag="KB913_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6821297.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            2261..3208
                     /locus_tag="KB913_003036"
     CDS             2261..3208
                     /locus_tag="KB913_003036"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBB6821298.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            3228..3755
                     /locus_tag="KB913_003037"
     CDS             3228..3755
                     /locus_tag="KB913_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6821299.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(3818..4471)
                     /locus_tag="KB913_003038"
     CDS             complement(3818..4471)
                     /locus_tag="KB913_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBB6821300.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            4603..5445
                     /locus_tag="KB913_003039"
     CDS             4603..5445
                     /locus_tag="KB913_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6821301.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            5603..6499
                     /locus_tag="KB913_003040"
     CDS             5603..6499
                     /locus_tag="KB913_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6821302.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            6502..7215
                     /locus_tag="KB913_003041"
     CDS             6502..7215
                     /locus_tag="KB913_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBB6821303.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            7235..7753
                     /gene="msrA"
                     /locus_tag="KB913_003042"
     CDS             7235..7753
                     /gene="msrA"
                     /locus_tag="KB913_003042"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6821304.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            7750..7977
                     /locus_tag="KB913_003043"
     CDS             7750..7977
                     /locus_tag="KB913_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBB6821305.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            8129..8680
                     /gene="lepB"
                     /locus_tag="KB913_003044"
     CDS             8129..8680
                     /gene="lepB"
                     /locus_tag="KB913_003044"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6821306.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(8763..9263)
                     /locus_tag="KB913_003045"
     CDS             complement(8763..9263)
                     /locus_tag="KB913_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBB6821307.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(9542..9796)
                     /locus_tag="KB913_003046"
     CDS             complement(9542..9796)
                     /locus_tag="KB913_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBB6821308.1"
                     /translation="MLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQI
                     AKENGGTFHEVDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT         3552 a         1712 c         1936 g         2659 t
ORIGIN      
        1 aaaaaatgct aagaggttat tatcttgaaa gaaaaatcat tgatgaatac gaagttgctg
       61 aaaaaatcac gacgttttct gcgaacagct atcgcaggaa tatcaatttg ttagaatctt
      121 atacgatgaa caaaccatct gataactttt ctttccgatt tgcgtttcga gcaaagtcaa
      181 aaaaaacgag tccaataaaa taaaaaggta aaaattttca agttttataa aaaacaaaac
      241 atatcagaac aggatcgaat cggtcctgtt ctttttttga gaacacaaaa agaacaaata
      301 ccaaaaaaat tttcctgaag ttcactattt ttatgataca atatccaaga taaggaggga
      361 acatgttgaa agaattaaaa gtaactgacc tcaaaaaaac ttatggtgaa aaagatttgt
      421 ttgaccagat ttcttttttg gtccacgaaa aagaccgtat cgggttgatt gggacgaacg
      481 ggacgggtaa aacaagtctc ttaaatatta ttgccggtat cgatagcagc gacggtgatc
      541 ggcaaacagt gttttatcca actgattacc gtattggtta tctttctcaa gcagctgaat
      601 tttccgatga attaactgtt ctccaagcag tctttcaagg aaacagcccc ttgatccaaa
      661 ctgttcgagc atatgaggaa gcattgatcg aactagggga aaacggagaa gaccctgatg
      721 tgcaaaaacg ttatgctaaa gcagaagaac aaatgaataa agaagatgct tggactacag
      781 ataccaacgc aaagattatt ttgcaaaaat taggaatcag tgaattagat aaaaaaatca
      841 gtactttatc aggtggtcag aaaaaacgag ttagtctggc gcaagtgttg attgatgaac
      901 ccgatttact attactagac gaaccaacaa accatttaga ttatgaagcg atcgagtggt
      961 tggaaaacta tttgaaacaa taccgtggcg cactattgat ggttacccac gatcgttatt
     1021 ttctagatag agtagcaaac cgaatcttcg aactttcatt tggaaaatta tacgagtata
     1081 aaggaaatta tgaagcttac gtcttagaaa aagcagaacg tgatcgtgta gaagtagaac
     1141 aagaagaaaa gcgcaagcgg ctttataaac aggaattagc ttggatgagg gctggcgtac
     1201 aggcacgtgg caccaagcag caagcacgga tcaaccgttt cgaagatcta aaggagaact
     1261 tgtaccaagt aaaccaagaa gatgatttag agctgaacct agcgacacaa cgtttaggga
     1321 aaaaagtact ggaaatcaaa gatggcagtt accgtataaa tgaccaaaca ctgctagaac
     1381 atttagattt attgattcaa tctcgggaaa gactaggtat tactggtaaa aatggtgcgg
     1441 gaaaatcgac attgcttaat attctagctg gcagaattcc cctggatagc ggtacaatgt
     1501 ctatcggtga aacggttcat cttgcgtatt atacacaaga aaatgaagaa atggcaccag
     1561 ataaacggat gattgcttac ttacaagaag ctgctgaaga agcaaaaaca gcagatggca
     1621 gtcaaatcgg agtagcagaa ttacttgaac gatttttatt tccaagattt atgcatggga
     1681 cactgatagg caaactttca ggcggagaaa aacgccggtt atttttgttg aaactgctga
     1741 ttcagcaacc taatgtttta ttattggatg aaccgaccaa tgatttggac atagcaacat
     1801 tgacgatttt ggaagattat tttagaagtt ttccaggtgc tgtgatcact gtttcccatg
     1861 accgttattt cttggacaag gtagcagata agttattagt attccaagga aacggaaaac
     1921 aagaacttta ttacggaaac atgtccagtt atttactgaa gcaaaaagag acccagcagc
     1981 ctgctgaaaa agcgaaacca aaaatacaga gcaaggaacc tgctgaaaag aagaaattat
     2041 cttacatgga acaaaaagaa tgggaaacga ttgaagatga gattgcagaa cttgaagaaa
     2101 aaatctcatt gctccaagaa gagatgaatc atcaaggaga taatttcact cgattacaag
     2161 aattgcaaaa cgacgtatct gaaacagaag cacaacttga agaaaaaatg gcacggtggg
     2221 aatacttgag tgaatgggta gaagattagg aggaaaaagg atggaacaag cgtatcttga
     2281 cttaggaaga aaattgttgg aagaagggca tcgtaaagaa gacagaacag gcacaggcac
     2341 attaagctta ttcggatacc aaatgcggtt tgatctgcaa aaagggtttc ctttgttaac
     2401 aacgaaacga gtaccttttg gattgatcaa aagcgaattg ctttggtttt taaaaggaga
     2461 tacgaatatc cgctatctat tacaaaataa aaaccatatt tgggatgaat gggcatttga
     2521 acgctacatc aaaagtccag actataatgg accagatatg actgattttg gccatagatg
     2581 tttgacagat cctgaattca atgaagaata taaaaagcag agcaagcttt tttgcgagaa
     2641 gatcctaacc gatgattcct ttgctgaaac atacggcgat cttggacaca tctacggcta
     2701 tcaatggcgt cactgggaaa caaaagacgg tggctttatc gatcaaatca aacaagtgat
     2761 cgaagcaatc aaaaagactc ctgattctag aagattgatc gtttctgcat ggaatccgga
     2821 agatgttcct agcatggctt tgcctccttg tcatacgatg tttcaatttt atgttcaaga
     2881 gggacggcta agctgccaat tgtatcaacg cagtggggat gtgtttctag gcgttccgtt
     2941 caacattgca agttatgcgt tgctgactca cctaattgca catgaaacag gtttagcggt
     3001 tggcgaattt gttcacacat taggagatgc tcatctttat atcaatcata tcgaacaaat
     3061 gaaagaacaa ttgagccgag aaatacgcgc atttccgact ttagttttga atcaggaaaa
     3121 gcagtcagta tttgattttg agatggaaga tatccaatta gaaggatatg acccacatcc
     3181 ggcgatcaaa gctcctatcg ctgtttagaa tcagaaagga tgagaaaatg ttagctgcaa
     3241 tttgggcaca ggatgaaaac ggattgattg gaaaagaaga ccgtcttcct tggcgtttgc
     3301 caaatgatct gaaattcttc aaacaaatga cagaagcaaa tacactagtg atgggacgaa
     3361 aaacattcga agggatgggt agccgtccgt tgccgaatcg tcagacgatt gttttgacga
     3421 gagattcttc ctataaagca gaaggcgtgc atgtcatgca tagtgtggaa gacgtgcttg
     3481 ctctggaaaa agaaacagac ggtatctttt tcatcgctgg agggtcagct gtttatcaag
     3541 aatttctgcc attttgtacg atattatacc gtacagtcat ccatcatgta ttcgatggag
     3601 atgcttattt tccacctgtt gactggtctg attggtcact gatcaatact agtcaaggag
     3661 aaatggatga aaaaaatcgt tatccgcatc aatttgaaac gtatcagcgt aatgagaatc
     3721 ctgtaaaaag cgggacaggc gaattgacga tataaaaaag ctatggatag actagctgtt
     3781 atttagagct gtcccatcca tagctttatt ttttttatta agtaaagaat aaaacagaga
     3841 agtacataaa acctgcacct aacataacaa acaaatgcca aacaacatgc atatagcgga
     3901 tagaattcaa gctataaaag aatgcgccta tcgtgtaaga aagcccgcct gctaccatca
     3961 aaataacacc agtcattcca agagagtgat aaagaggaac agcagccacg acacagagcc
     4021 accccataaa aatatagatg atcgtagata cttttgatac tctctcccgt ttatgcaacg
     4081 tcaacgcttt atatataatg ccaagaatcg caaacaacca gattaataca aataaagtcc
     4141 aacctagcca tcctcggata ctcagcaaac aaaaaggagt ataacttcct gcaatcaaaa
     4201 gaaaaatcga actatgatcg aatacttgga acaccttttt tgcttttgta aaaatcaatg
     4261 aatgaaacaa agtagacgtt aaaaataaaa gaatcatcat cgatccatag atagcataag
     4321 agacaatatg gagggaggaa tgcaagtggg caccttttac taaaagaacc actagtcccg
     4381 cgatactcaa tccagtccca attccatggg tgactgcatt aaacacttca tttaatattt
     4441 catacgttcg attaaatttc gttttttcca tgaaaacggc tcctttacta ggtgtaatta
     4501 atgaaaaatc attatttgtc tgttatacta aaaatagaaa ttgtcttaca tgtagtttaa
     4561 catgaataag gcatcttgtt aaagaaagag agagagaaaa taatgacaaa tgtaaaaatc
     4621 gtaacagatt cttcatgtac gatggaaaaa aatgtacgcg atgctttagg cattcgtgtc
     4681 atgccgctat ccatcatgat cgacggaaca gtatatcccg atgatgacca actagacggc
     4741 gaaagattta tggaaatgat ggcgaaagca aaaaatctgc ccaaaacaag ccaaccacca
     4801 attggagaat tcatctcgat gtatgatgag ctaggagaag acggcagtga agtgatttcg
     4861 atccatatga caaaaggctt gagtggaaca gtagaagcag caagacaagc cagtaatcta
     4921 acaaaaacga aagtaacggt tatcgacagt gataccactg accaaggatt atcttttcag
     4981 gtaattcgag cagctgaatt agcaaaagaa ggtaaaacag tagagaaaat ccttgaagaa
     5041 gtcaaaaaag tacaagacaa tacaaaatta tacatcggaa tatccacact agataacttg
     5101 gtaaaaggtg gaagaatcag ccgaacaact ggtttgctgt ctagtgtttt gaacatacgc
     5161 gtggtgatga atttcgccca ttctgaatta atccctgtaa ctaaggggcg aggaaagaaa
     5221 acgttcgata aatggtttaa taatttgaaa aatgaactga aagaattgcc aaatgtgcga
     5281 caaatcggta tttcacatgc ggatgcaaaa gaattggcgc aagaattcaa agagggtttg
     5341 caagaattat tcccggacat gcatatccct gtactgcata cgaatccggt tatcgctacg
     5401 catactggta aagacgcgtt tgcaatcatg tattatgtag attagtcgaa aagaggataa
     5461 gccctcagcc tgaaaggctt gcagcttatt ctctttttct ttataaaatt aggaaaataa
     5521 ttgttttctt ttttcataaa gactaccttt ttgataaaat ttttgataac attagaacca
     5581 atcgaataca agaggtgaaa aaatgaaatt aacgaaacga catttgatcc tcgttttgtt
     5641 cccattatta attgcgatca tcatctatgc aggtttagct gcttctatac cgaaagctgg
     5701 cccactaatg aaaccagtaa ctactgtgag agaagatcca aataaaaaag aaaaacttca
     5761 ctacatagct atcggagatt cgctgactga aggagtagga gatcaaacca agcaaggagg
     5821 attcgttccc cttgtcgcaa atgatctaaa agaccgttat aatttgaccg cggttgaaac
     5881 agaaaactat ggtgtaaatg gtgaacgaag tgaccagatc ttaaagcgag taaaaacaaa
     5941 agaagaaatt cgaaacaata tcaaaacagc tgattttatc acactgactg ttggcggtaa
     6001 tgatttgatg aaagttatcc aaaataattt attcgggtta acggtcaatt cctttaaaaa
     6061 gccactgaaa aactatcagg aaaatgtcac agaactattg gaagaatttc gatccctcaa
     6121 taaaaccgca cctatttaca ttttaggcat ctacaatcca ttttatttga actttcctga
     6181 gatcactgac atgcagacaa ttgttaacaa ttggaacaaa ggaacagaaa cggtgacaaa
     6241 aaaaatgccg aactgctact ttatcccaat caatgatttg ctttatcaag gattgaatca
     6301 ggaagtaggt gtcacagaag aaggaacaga tcaaacaact agcacgacag aaaatctaaa
     6361 tggcatcaaa aataatgtgc tctatgaaga agatcatttc catccaaata atttaggtta
     6421 tcaattgatg gcaaatgcag tgagagatca gctgatcgag acacaaaacc aatggttaga
     6481 gaaggaggat gatcaataaa catgaaaaca agatctgacg tatcttcaaa caaaacaaag
     6541 aaaacaaatt actggaaatt cgccttcctt atccttcttg gggtagtact tggttcgacc
     6601 gtatttttag gcagccgtat ttttgctaat cgggaaccag aactcccaga aataccagct
     6661 cttacggaaa gacaaggaga tcctgtctta acgatcaatt caaataaaga aaaagtcaat
     6721 caaatcatca gctttttcct tagtgagtat caaaaagata gtgatattga atataaattt
     6781 tatttggaaa atgaagcact actcaatggt actttcgaag tactaggttt tcctatcgat
     6841 ttctatttat attttgatcc gtatgtgatg gaaaacggaa atgtccaact aaaagctaga
     6901 agtctttcta tcggaacatt gagtttgcca atcaaagatg tgatgaatat gatcaagaga
     6961 aactataaat taccagattg gatcgaagtc aatacagatg atctgactat catgcttagg
     7021 ttggatcaat tccgaatgca aaacgggatg tatattaaag cagataaaat cgacttagta
     7081 aatgatgaca ttcggtttag tctatatttg ccaaaagata cctctgatgc ttcaaacaac
     7141 tcaaatacca acaaaactag caccagcagt actgaaagca agacaaaaga aaataaaaaa
     7201 tcatcggatg agtagtatta gagggggaat cataatggaa cgagcaatat ttgcaggagg
     7261 ctgcttctgg tgtatgatcc agcctttcga cacgcttcct ggtatccata cagtgatgtc
     7321 aggatatact ggagggcatg taccagatcc gacttatgaa caagtaaaaa gccaaacgac
     7381 tggacataca gaagcagtgg agattatcta tgatccaaca ttgatttcat atgaacaatt
     7441 agtagaactt tactggcagc aaactgatcc aactgacgct ttcggacaat tcgaggatcg
     7501 cggtgacaat tatcgcccgg tgatctttta tttgacagaa gaacagcgga tcattgctga
     7561 aaaaagtaag aaacagttag ctgaaagtgg acgtttcgaa cagccaatcg ttacaaaaat
     7621 cgaaccagcc caaccatttt atctagcaga agaagaccat caagagtatt ataaaaagca
     7681 tcctgaaaat tttaaaagaa accatgcacg ccgggctgcc tttatcgaag aaaattggag
     7741 gaacgaaggg tgaatcgaag cttttttcat tatttaatga cactgcgagg cggtggcaca
     7801 catgatgctt tatctgtttt cgctacagaa gccggtaaag acatccaatt tcctaagcac
     7861 agctctagct acgaagaaat ttctaattat ctggaactga atgtcgacta tttgccgtcc
     7921 atggatatct ttgacgaagc atgggaaaaa tatttagaaa ataatcatga catataagag
     7981 atagttttgt actttatgat caaaaaagtt ttttgtccaa tagcctaatt gaaagaatta
     8041 tttttatttc agctatctag tcgcattttt ttgatatttt tcttataata aagaaagaat
     8101 gaaaaaaaga gggatggatt gatagagatt gacaaaaaaa caacgctata ttaatcgctt
     8161 ctggcttgta ttcaaatact tacttgtttc tgtattcctt gcgttcatgt tgcggggatt
     8221 tttattcatc ccggtaccag tggaaggcaa ttcaatggaa aacgtgttga agcaaggtga
     8281 tatggttgtg atggaaaaat tttcggagat cagacgattt gatattgttg tttttcaatt
     8341 agcagatggc acgatttata tcaaacgagt aatcggtctt ccaggagaaa atgtcagcta
     8401 ccaaaatgat caattgaaga tcaatgggaa agtagttaag gaaccttatc taactaaaaa
     8461 cctgaaatca gatcatgcaa atgcatccta tacgacggac tttacactac aagagctaac
     8521 gggacaatcc aagcttccgg aagataatta ttttgtactt ggagataatc gaagagtttc
     8581 aaaagatagt cgttcgtttg gcacgatcaa taaaactgat attctaggta aagcaagatt
     8641 tgtctattat ccacttgatg aaataaaatg gatccagtga gaaacaataa agcgtgcagt
     8701 ctgttgagac tgcacgcttt attgtttaat ccaaaatcag tttactacct tagtacgtaa
     8761 aatcaaacag ctcgtttaaa cacttttcta gcctctaaag ttttgataaa tgaataaaca
     8821 accattattt gaatagggat ttggatcata ttcctgatga atctacctag aaaaattact
     8881 ttgaaatctg caccaaacaa aacagacatc agccaagaat tgataaaaag gctgactggg
     8941 atcataatca ataattgggc agcgatgacg gaaggcaggt ttatcttttt atgatataaa
     9001 aataagccat taataaatcc accaaggaaa gccgtgataa gaaaagcagc ttgaaacgtt
     9061 cctgaaccaa atatcgtgaa atttaaagtg ttcgacaaca tttcaagcaa accagcccag
     9121 atcggtccat atagataacc cataagcgcc atacttaaaa atccgaatgt gatttgaaaa
     9181 taagcaggac caatcgctat cttgtataag atgacatcaa gggctaataa aagagcagag
     9241 gtcgacaaca atcttgcatt catttcgggc aatctaaaaa cgtcttttgc aatcaaagtg
     9301 ttcaaaatat tctctccttt gtcagttaat aataaaagga taccataaaa tcaccaatgt
     9361 gtcatgacac attggtgatt tacatacact ggcatctaac aattaaaaaa agggtgagaa
     9421 gactgctttt ataaactgta aaaaagagat tgtacgaata aaaaaaatag aggcggagaa
     9481 tacttatcgt atcatccgcc tttgtttttt tgttataaaa aacgtcagat tagttatctg
     9541 cttacatctt catccatacg ggttctaatg tatttccgtc tagatcttgg acttctaatg
     9601 aaaacatttc ttcttcaggc attcccatat ctacttcgtg gaaagtacca ccattttctt
     9661 ttgcaatttg agcaaatttt tttacttcat ccgcattttc aacactaaac gaaatcaaag
     9721 caccacttgt ttttttatta tcagctattt ctttatcttt tataaatttt ttataaaaat
     9781 catgagagag aagcattatc caaaaagtgt catcccatac cattgaacca gcttcttcag
     9841 tagaaaattc ttcattttt
//
LOCUS       DADVXE010000222         5412 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.guided.122, whole genome shotgun sequence.
ACCESSION   DADVXE010000222 DADVXE010000000
VERSION     DADVXE010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5412
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.guided.122"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            322..1014
                     /locus_tag="KB913_003047"
     CDS             322..1014
                     /locus_tag="KB913_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6821309.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSWKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1341..1838
                     /gene="dfrG"
                     /locus_tag="KB913_003048"
     CDS             1341..1838
                     /gene="dfrG"
                     /locus_tag="KB913_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBB6821310.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1910..3862)
                     /locus_tag="KB913_003049"
     CDS             complement(1910..3862)
                     /locus_tag="KB913_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBB6821311.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3869..4105)
                     /locus_tag="KB913_003050"
     CDS             complement(3869..4105)
                     /locus_tag="KB913_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821312.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            4507..4797
                     /locus_tag="KB913_003051"
     CDS             4507..4797
                     /locus_tag="KB913_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821313.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT         1832 a          882 c          936 g         1762 t
ORIGIN      
        1 tttcataggt aaaagaagca tgacaattta tgacaaatcc gcgttttttg taataaatac
       61 agtaatctat gaaatgaaaa gggttacgtt taataaaact tgcttttttg tttttgttca
      121 ccataaatat ttatttaaga aagtattaac ctgcattttt ctctataaaa aagatttttt
      181 aaatagataa aaaaggagga ttaaatgagt atttgatagt atttatatta aaattacata
      241 tgtaatttaa aaacgcttga cattgtgttt gagatcactt acttttagca tgtaaaagta
      301 ttggattaag gagctatgca aatgaaaaag aaatttatta ctggtgggat tgtcgttgca
      361 tttctatgtc taattggcta cacaggcacg cggtacgcaa atgaaattat tttgtggggt
      421 ggagagacag atattgatac aatcaatgag aatctgacac agcttgatca tacattgaca
      481 gataaagagc aagcgattac agatcttacc gctcgactag cacaaaaaga acagacattg
      541 caagattcaa aggcagatgt ccaagaatac caaacaaaag taaatgaatt agaaaaccaa
      601 aaaaatcaat cggcagcaga aaaacaaaac ttagaaagtc aattagtcag caaggatgca
      661 caactacaaa gcaaacaaaa tgaaatcaat gtcaaactag atgagatcaa ccaaaaaaat
      721 gatgaaatca atcatctgaa tgcagattgg acagcaagac tacaagaagc acaagcaaaa
      781 ctttcagaat tacaaaatac tgtaaatggt ttgaatcaac aaatcgcaac actgacacaa
      841 gaaaaaacaa atgtagaaac tcagttaaca gatacacaaa agaaattaga cgaagcaact
      901 gctgaaaact caagctggaa acaatatatt caaaagttag aaaaagcaaa agatgaagtg
      961 gaagatacag ctgataaatc tcagcaaatt gttgaagaac atttgcgtaa ataatctttc
     1021 ttaacaagta aacctaaatt agtaaagaag caacagtaat ctatactaag tagttcagtt
     1081 ttggagtaca aaatgacaaa atgtacttca aaatggacta cttttttcat tttaacttac
     1141 ataccaaatt acatacaaaa tgatttataa aatgcaattg aaaatgataa ttgaatgaaa
     1201 atttgtgatt ttgtggtatt atgataatat aacttataga aaaaattgct tattcaacta
     1261 acgggcagga taatgagaaa aggttttttg atagaaataa gaaattagat ggtaaattag
     1321 ttaaaaaggc tgtgttataa atgaaagttt ctttgattgc tgcgatggat aagaatagag
     1381 tgattggcaa agagaatgac attccttgga ggattcccaa ggactgggaa tatgttaaaa
     1441 atactacaaa gggacatccg ataatattag gtaggaagaa ccttgaatca atcggaagag
     1501 ccttacctga cagaagaaat attattctga cgagagataa ggggtttacc tttaatggtt
     1561 gtgaaattgt tcattcaata gaagatgttt ttgagttatg taaaaacgaa gaagaaattt
     1621 ttattttcgg aggagaacag atttataatt tgtttttccc ttatgttgag aaaatgtaca
     1681 tcacaaaaat acatcatgaa ttcgaaggag atactttttt tccagaagtg aattatgagg
     1741 aatggaatga ggtatttgcc caaaaaggga taaagaatga taaaaatccg tataactact
     1801 attttcatgt atatgaaaga aaaaacttat tgagttaacg ggtgcgttaa ttgaagaaga
     1861 acagtaaaga taaagcacaa gagcttggga ttactccaag ctctttttgt catttgaaat
     1921 aaattatatc tttccaatca aattgtttat ctgtaatccc taatctttga gcaggtgtca
     1981 aaaccttttt atccgctgat ttaaaagggc gacaaaagtt gtagtaagtt cttagaattg
     2041 taatcgcaaa ttgagcatac ttcggattga agttagcgta aatatagctc ttcttatcac
     2101 cacgagctgt tgttaatggt ctttcaagag atgatatata acgtcttatc tgttgaataa
     2161 agctattggt cgaatggtca ttaacattta atagcatctt tgcgatttcg tttggttcca
     2221 gagcagataa atccgttcta caatcaactg aataaaatcc tttatcctta gtggctaatg
     2281 gatgtttgat agggttatcg gcatatttgc gatatctttc tccatcttta ctaatagcct
     2341 cttcgtggaa ttgatgactt gttagtaatt cagttagata atgagatgcc aaagtccgta
     2401 gaaactttgt tttgaatcct ctgatatctc cccaatcgag cagttctgct tttgcttgtc
     2461 cgaattcttt taagcattgt tttctgcttt tcgtcttgtt aacttggcaa ataaaatgat
     2521 gtgcatcgct caaccttaat tctttcgtga atactctata aaaggcgttt ctaatagaga
     2581 agtcatcatc actaatcatt cgccattcgt cggcattaac catttgttta attaaccaat
     2641 agtgagcagt tgtagtataa ggagcatcaa catttaaacc atcgacaaat ctactcctat
     2701 tagtaatttt ccctaattcg tgaagataag cattcctatt ttcgctatcg ttagcggatg
     2761 gttcttgtgg ataataagac caatctaacc tatcattttt acgactaaaa gtattgagat
     2821 ggtcttcttt gaattttctt gtatcttcat ttaattcatc cattgaaata ttccaatcat
     2881 aggcaacatc agaacggaac acatatcttg ataagacctc agcagataca actatatacg
     2941 tttgcatatt aaggtcttca aaccccgtat atttctttga accttgtcct ttcttacgga
     3001 cgttatttag gtagtagtgc atcttgtccg tattaagcca catctcgtta aatttctttg
     3061 tttgaagggg ttgtgtctca tatcgttcta aaaactccaa acaacgccta tacagccact
     3121 ccagcttatg atagtaggtt ccaactccaa ttcctaaaat atcacaagta cgactgactg
     3181 aaacccttcc aacaaccatc ttagcgaaca ttggaagaat ggtgttcttt tgttggtgat
     3241 aagtagtggt ttcttctctt tttggtagaa cattagtgaa cttcttacac gccttacatt
     3301 gatagcgttg agatttgccc ctacttttcc cccttttgta aaattgcttc ggctcattga
     3361 atggggttga ttcttcttcc gagcagcctt ctttatgaaa ttgataatct ggctcaacat
     3421 cttggatgct attgatttct ataaggcgtt taatttcttc aacaacagac caattagata
     3481 aaggggttac tgtacagttt tgcgatacac ctctgccaat aggattgtca ttgcagtaca
     3541 tacctttatg acctttatct ttggaactac cagtcatttt atatcgactt ggtttccctt
     3601 ttacatcttt gaatttgtgc tgttctttcc caaaattaca acaaaacgga ttgatgcagt
     3661 aattatattg aatgggatat tcagaaccgt tccatttaaa agacgttggc aagaacaaca
     3721 ttttgttata ccttgttgca aatcgttttg gagttaataa atcatattgt ttagccctat
     3781 cttttaattc ttcgtttgaa atcggaattt taacatctac aatttcatct tccttcgtgg
     3841 ctaatctttt aagcttggtc attgtctatc aacccactct atctttgata cccatttttt
     3901 caacaatccg cttattactt cgcttgttgg caatccattc aataaacttc ttatcgtcta
     3961 aaatgttcaa taagaattca tccactgctt cgctttcagt acgctctgca tattcagcgt
     4021 attgcttaac tatcaccctt acttgctctg atatttccca atccacagac ttagcgttct
     4081 tattttttgg ctcaagaaat tgcataggaa aatgcacccc tttttgctta gtaaattgta
     4141 accattttaa cacaccaatt tgcattccta caataattat ttcacgttcg catttttata
     4201 tacattttaa cttacatttt gtggtgtaaa ttaacaacaa acgttgattt aacaataaaa
     4261 aacgagtatc aaattcagtt gcaatttgat actcatttag gtttacattt tcactttttg
     4321 tactccaaaa ctgaactact taaatctata ctgctgcctc ttttttttag tacatgtcct
     4381 tcatcttcgc aggaagtgcc aatatgattt taagaaaggt aatagacaaa aagtcaaaaa
     4441 gataaaacag agtttcttct ttacaaaggg aatgtatgtt cgtataatgg tattgaggtg
     4501 aaggttatgg agaaaaaata tggaacagta gataagatcc gtactttgca agttagtgcc
     4561 agaccgttga tccgtttcag tttaaatggg gtcaattgtt tgattgcttc ccatagtttg
     4621 aacttcctag ctgaagtaga cgaagggatg aagttagtcg ttacaggtta ttataataat
     4681 agaaagcaat ttgttgtgag atcctatcat gtgttaggga aacccaaaat tgtggtagaa
     4741 tatgagaaaa gtctataccc aagaaaaaag gtccgacaag atgaaagaat aaactagaaa
     4801 acaagcggct gagacaaaaa tgtcctagcc gcttgttttg gaaagatgga tgcagacgat
     4861 gggatttgaa cccacacgag catacgctca caagaacctc aatctatata taactacatg
     4921 tatttaagta tttgtgatga atcactaaac tttccaaact catttgaggg atattgctta
     4981 aagattgaac agatcaattc gaagccctat tagtattcgc tcaatggggg gatcagaggc
     5041 cataaaaaga gactagtcat tactagtctc aggtagtgga attgtaggat tttaaacgtt
     5101 cctggagagt accggtatgt aactcgaaga ggtgattatc atagtcgtaa aagtaaattg
     5161 aagaagcctc gcctttcaca cgagaacgtc ctggttcgac agttaaacct aacatttgga
     5221 tttttgagac aaacgaatct atatcttgtt cgtcaatttt aaaagcaata tgattgtatg
     5281 tctttggcag tttattcgac gaattctgca ttactgcaat ccataggtcc ttaactaaga
     5341 aaaatttttc tggatataat gaaaattttt ttgttgacta tcgtagattt cttttgcatc
     5401 aaataaggta tt
//
LOCUS       DADVXE010000223         4702 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.guided.133, whole genome shotgun sequence.
ACCESSION   DADVXE010000223 DADVXE010000000
VERSION     DADVXE010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.guided.133"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            194..1000
                     /locus_tag="KB913_003052"
     CDS             194..1000
                     /locus_tag="KB913_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HBB6821314.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            1018..1725
                     /locus_tag="KB913_003053"
     CDS             1018..1725
                     /locus_tag="KB913_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBB6821315.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            1722..2693
                     /locus_tag="KB913_003054"
     CDS             1722..2693
                     /locus_tag="KB913_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBB6821316.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2686..3714
                     /gene="vanB"
                     /locus_tag="KB913_003055"
     CDS             2686..3714
                     /gene="vanB"
                     /locus_tag="KB913_003055"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBB6821317.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3720..4328
                     /locus_tag="KB913_003056"
     CDS             3720..4328
                     /locus_tag="KB913_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBB6821318.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(4394..4567)
                     /locus_tag="KB913_003057"
     CDS             complement(4394..4567)
                     /locus_tag="KB913_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6821319.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         1329 a          986 c         1245 g         1142 t
ORIGIN      
        1 gatagaatga ttttctatca gtcctagaaa ttatagagcc gattttgacc gacaggtata
       61 accctgccgg tctttttttg ctgctacagg aaaactacag actggctaca gggaaagtac
      121 agatgcgctt gccataataa caatcgtacc agccacaaat cgtagtttta ttgcaaagga
      181 ggcattcgat caaatggaaa aaagcaacta tcattccaat gcggatcatc acaaacggca
      241 tatgaaacaa tccgtggaaa agcgggcttt tctatgtgcg ttcattattt cgttcacagt
      301 ctgcacgctg tttttggggt ggagactggc ttccgtattg gaggcaacac agataccgcc
      361 catccctgca actcatacag gcagcagcac tgacgtagtg gagaatttgg aggaaaacgc
      421 tcttgccacc gccaaagaac agggagatga acaggaatgg agcctgattt tagtgaacag
      481 gcagaacccc atccccgcac agtacgatgt ggagcttgag caactatcaa atggtgagcg
      541 gatagatatt cggatttctc cctatcttca agatttgttt gatgccgcaa gaactgatgg
      601 agtttacccg attgtcgcat ccggataccg aacaacagaa aaacagcaag aaattatgga
      661 tgaaaaaatt gccgaatata aggcgaaagg ctacacctct gcacaggcta aagcggaagc
      721 agaaacttgg gtggccgtgc cgggaacgag cgagcatcag cttggtcttg ctgtggatat
      781 caatgcggac ggaattcatt caacaggcaa cgaggtttat agatggctgg atgaaaacag
      841 ctatcgtttt ggttttattc gtcgctaccc accagacaag acagagataa ccggtgtgag
      901 caacgagccg tggcattacc gatatgttgg catcgaagct gccacagaga tgtacaacca
      961 aggggtttgc cttgaggaat atttaaaacc agaaaaatga gaaaaggatg ttatgttatg
     1021 gacagaaaaa gattgacaca gcgtttcccg ttcctgcttc caatgagacg ggcgcagaga
     1081 aaaatgtgct tttatgcggg aatgagattt gacggctgtc gctatgcgca gacgataggg
     1141 gaaaaatcgc tttcccattt gctctttgaa acggattgcg cattatacaa ccacaatacc
     1201 ggatttgaca tgatatacca ggaaaacaag gtgttcaact taaagctggc agcaaagacc
     1261 ttaaacggct tattgataag accgggggaa accttttctt tctggttgtt cctgcatacg
     1321 ccattgacaa ttatccagcg cagaggtcac gaagtaaagg agtttccaga gccaaacagt
     1381 gacgagatta aaggggtgga tgcaaccatt tcagagggct ggattgattt aaaagtgcga
     1441 aacgataccg actgcaccta ccaaatatgg gtgaccttag atgatgagaa aatcatcggt
     1501 caggtgttcg ccgacaaaga gccccaagca ttatacaaaa ttacaaatgg cagtatccag
     1561 tatgtccgtg aaagtggcgg gatttatgaa tatgcccagg ttaaacggat gcaagttgcc
     1621 ttaggtaccg gggaaataat agattgcaag ctgctttata caaacaaatg caaaatctgt
     1681 tatcccctcc cggaaagtgt ggatattcag gaggagaacc aatgagaaaa agtgtgggca
     1741 ttactgtttt tggatgcgaa caggatgagg caaatgcttt ccgcgcttta tcgccggatt
     1801 ttcatattat ccctacgctg attagcgatg cgatatcggc agacaacgca aaattggccg
     1861 ctggcaatca atgcgttagc gtaagccata agtccgaggt ttccgaggcg acaattcttg
     1921 cgctgagaaa ggtcggggta aaatacattt ctacccgcag catcggctgc gatcacattg
     1981 atacgactgc cgccgagaga atgggaatct cggttggcac ggttgcgtat tcgccggaca
     2041 gcgttgcgga ttatgctttg atgctgatgc tgatggccat acggggtgca aaacccacca
     2101 tgcacgccgt ggcgcaacaa gatttcagat tggatcgtat ccgggggaaa gaactggggg
     2161 atatgactgt gggagttatt ggaaccggcc atatcgggca agcggtcgtc aaaaggctgc
     2221 ggggatttgg atgccatgtg ctggcctatg ataacagccg aaaaatggat gcagattatg
     2281 tccagcttga tgagcttcta aaaaacagcg atattgttac gctccatgtg ccgctttgtg
     2341 cggatacccg ccatctgatc ggtcagaagc aaattggaga gatgaagcaa ggcgcatttt
     2401 taatcaacac cgggcgcgga gcgcttgtcg ataccggggc gctggtggag gcgttggaaa
     2461 gcggaaagct gggtggtgcg gcactggatg tgttggaggg cgaggatcag tttgtttata
     2521 ccgattgctc gcagaaagtg cttgaccatc cctttttgtc gcagctttta aggatgccga
     2581 atgtgatcat cacaccccat acggcgtact acactgagcg tgtgctgcag gatactacag
     2641 aaaaaacaat caggaattgt ctcaattttg aaaggagttt acagcatgaa tagaataaaa
     2701 gtcgcaatca tcttcggcgg ttgctcggag gaacatgatg tgtcggtaaa agccgcaata
     2761 gaaattgctg cgaacattga tacggaaaaa ttcgatccgc actacatcgg aattacaaaa
     2821 aacggtgtat ggaagctatg caagaagcca tgtacggaat gggaagccga cagtctcccc
     2881 gccatactct ccccggatag gaaaacgcat gggctgcttg tcatgaaaga aagcgaatac
     2941 gaaacacggc gtattgatgt ggctttcccg gttttgcatg gcaaatgcgg ggaggatggt
     3001 gcgatacagg ggctgtttgt attgtctggt atcccctatg tgggctgtga tattcaaagc
     3061 tccgcagctt gcatggacaa atcactggcc tacattctta caaaaaatgc gggcatcgcc
     3121 gttcccgaat ttcaaatgat tgataaaggt gacaagccgg aggcgggtgc gcttacctac
     3181 cctgtctttg tgaagccggc acggtcaggt tcgtcctttg gcgtaaccaa agtaaacggt
     3241 acggaagaac ttaacgctgc gatagaagcg gcaggacaat atgatggaaa aatcttaatt
     3301 gagcaagcga tttcgggctg tgaggtcggg tgtgcggtca tggggaacga ggatgatttg
     3361 attgtcggcg aagtggatca aatccggctg agccacggta tcttccgcat ccatcaggaa
     3421 aacgagccgg aaaaaggctc agaaaatgcg atgattacag ttcccgcaga cattccggtc
     3481 gaggaacgaa atcgggtgca ggaaacggca aagaaagtat atcgggtgct tggatgcaga
     3541 gggcttgccc gtgttgatct ttttttgcag gaggatggcg gcatcgttct aaatgaggtc
     3601 aataccctgc ccggttttac atcgtacagc cgctacccac gtatgatggc cgccgcagga
     3661 atcacgcttc ctgcactgat tgacagcctg attacattgg cgttaaagag gtgataagta
     3721 tggaaaatgg ttttttgttt ttagatgaaa tgttgcatgg cgtccgttgg gatgccaagt
     3781 acgccacatg ggataacttc acaggaaaac cggtggatgg gtatgaggtg aatcgcatca
     3841 tcggcacaaa ggccgtggcg tttgctctgc gcgaggcaca aatccatgcg gctgcgcttg
     3901 gctatggctt gcttttatgg gatggatatc ggccaagaac tgcggtggac tgcttcctgc
     3961 gttgggcagc gcaaccggag gacaatctca caaaagaaaa attttacccc aatatagagc
     4021 gagccgagtt gattacaaag ggttatgtgg cctcacaatc cagccatagc cgtggaagcg
     4081 caattgatct tacgctctac cacctggata caggggaact tgtttcaatg ggaagtaact
     4141 tcgattttat ggacgaacgg tcgcatcata cagcaaaagg gataggggat gcagaggcac
     4201 aaaatcgaag atgcttgcgt aaaatcatgg aaagcagcgg atttcagtct tatcgctttg
     4261 aatggtggca ctataagttg attgatgagc cataccccga tacctatttt aattttgccg
     4321 tttcataatg aaagtattgg ttttgtatca gattttggat ttgataaaat ctatgctggt
     4381 catggacaat cttttactgg aaagtggtta aagcatcttt tgtaatacat tgcaaattat
     4441 agtattcaat ctgcccagcg gcagaaaaga aaaaaaccgc tgttgggcag acctttccca
     4501 cgcccatttt gtattttgct ggcggcggtt ttgagaaatc aaggccgccg ttcttttctg
     4561 gcagcaaaag gtgtggcggc ccataggagg atgccgctat gctgttttgc tattgccatg
     4621 ctctaatcca cttccaccac tcaaaaaaag ccttgcccct ccatgaactg aaccccaaaa
     4681 gttgaactat ttaatggact gt
//
LOCUS       DADVXE010000224         4259 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.guided.137, whole genome shotgun sequence.
ACCESSION   DADVXE010000224 DADVXE010000000
VERSION     DADVXE010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.guided.137"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            209..1687
                     /gene="msr(C)"
                     /locus_tag="KB913_003058"
     CDS             209..1687
                     /gene="msr(C)"
                     /locus_tag="KB913_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBB6821320.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            1734..2180
                     /locus_tag="KB913_003059"
     CDS             1734..2180
                     /locus_tag="KB913_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBB6821321.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(2379..2894)
                     /locus_tag="KB913_003060"
     CDS             complement(2379..2894)
                     /locus_tag="KB913_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6821322.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            3011..4213
                     /locus_tag="KB913_003061"
     CDS             3011..4213
                     /locus_tag="KB913_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6821323.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         1270 a          717 c          927 g         1345 t
ORIGIN      
        1 gtataaacaa caatttcatg gatggagtat gtccattttt tcgaacgaca gtagaatagg
       61 tgaaagctat gacagatttg gtgatttagt catagttatt tcgttcagag taggaaaaga
      121 tgtgatgcag tttttttgca aacagatttt tctgctcttt tttagtatcg ataattgttg
      181 ttttacatga aataggagtg taaaacatat ggaaaattta gcagtaaata taacaaatct
      241 acaagtcagc tttggcaacc agctagaact atctattgat tctcttcgtg tctatcagca
      301 agatcgtata gggatcatag gagaaaatgg tgtcggtaaa tcgactttgc tcaaactaat
      361 agccggtgaa ctttttcccg atcatgggaa aatccaaaca gagatcacct tcaactacct
      421 gcctcaatta acctatctcg ctgaagcaaa ggacctaaat ttggaattag ccagtcattt
      481 ccagttaaga ctggaagaaa cttcagagcg gaaatggagc ggaggggaag aacgaaagat
      541 cgagttgata cgtcttcttt cttcttatga acaagggatg cttctagacg agccaacaac
      601 ccatctagat agaaaaagta ttgatcgact gattgaagag cttcgttatt attatggtac
      661 gctggttttt gttagtcatg atcgctattt tctagatgag ctagcatcga aaatctggga
      721 agtaaaagac ggagaaatcc gagagttttc ggggaattat agtgcctatc tcactcaaaa
      781 ggaattggag aaaaagactc agctacgaga agcagagtcg atcatgaaag agaaaaaacg
      841 attggaaaaa tcgatccaag aaaagaaaaa acaagcggaa aagttggaaa aagtgtccag
      901 taaaaagaaa aagcaacaaa tcagactgga tcggttgtct tcctctaaac aaaaagacag
      961 tgtacaaaaa gccatccaaa agaatgcgaa aacattagag agaagactcc aaaaaatagg
     1021 agaaacaacc aagccgcagc agatgaaaca aatccgtttt ccagtaccaa aatctcttga
     1081 actccacagc cgctatccca tcatgggaca aaatgtccaa ttggaaagaa gtgggagaac
     1141 attactggta aatggtgatt ttcagttttc tttaggtaaa aaaatcgcga ttgtcggtga
     1201 aaatggttca ggtaagacaa ccttattaga acatatccgc aaacaaggag aaggaatcct
     1261 tctctctccg aaagtaagct ttcaagtata tcagcaaaag ggttatcaaa tgacatctga
     1321 agaatccatc attcgttttg tcatgagaca aacagagttt tcagaatcgc ttgtccgtag
     1381 tttgctgaat cacttagggt ttgctcagga aactttgacg aaaccgttat gtacattaag
     1441 tgggggagaa gcgacccgtc tgacgattgc tttgcttttt actaagccaa gtaatgtgtt
     1501 gctgttagat gaaccgacta attttattga tatggcaacg atcgaagctt tagagaagct
     1561 aatgcaaata tatccgggaa cgattttgtt tacttctcat gattcttact ttgtcgagcg
     1621 tacggctgat gaagtttatg aaataaaagg gcagaaaata aaaaaagtac ttacgagaaa
     1681 tttttaaatg tgctacgatg attttcgtga caaatttaaa ggagtggtac agattgccta
     1741 caaataaaaa agaaggaata atttttacaa caatgatgtg ttttttgatg gtcttgggga
     1801 tgagcgcgta taatttatgg ctgcatcaag atcttcattt atcaagtttg ttgattggtc
     1861 tagtgcctgg attcgtggtg gctttcattt tggatgtctt catcatcggt gtgctggcga
     1921 aaaaaattgc ctttaaacta ccagtaaatc cagaaagcaa ggtccaaatg atcttaacta
     1981 tttcatgctt gatggtttta ggaatggtga catgtatgtc tttattcggt gtgatcatgg
     2041 aacaaggaat acctgatcaa ttattctctg cttatatgaa tgcttggaaa atgaatgtga
     2101 ttgccgcttt accgttgcag ttgatcatcg ttggcccgct ttcaagaagt gtgctaaaag
     2161 caattcaaag taatgaatga tggaacactg ttatttgaaa aaaggccttg gcatgctttt
     2221 tgtcatagtc tcttgaatgc agttctagaa aaatagtgat ccgaacgata ggttttggcc
     2281 tgtcgttcgg atcgcttttt cttttccaac tgtattgctc ttttattgaa gataatttgc
     2341 tcttcaatag atatttctag aaaggttctg tttatccctt actcaaaaaa ctgctgcatt
     2401 tgttctctta cttgctgaca ccattggagt tcctgctgac aaagcataat tctgcgctgg
     2461 atcacaacat aacgtccaaa ttcttgtttc ttgtctagcg agaggtcatt caattttttt
     2521 tgattttttt gcatgatttt gttcagctgt tgttctctag tgaatagcag tccagtagct
     2581 gttgttttat cgagcgtcga aaaagcatag atttttgcta gaaattcatc tttttgcgta
     2641 ggagcgggag tttcctcttt gatccattcc tctacaagag cacgtccttc atcagtcaag
     2701 tggtagatct ttttttgaga gtgctcgtct ttgtccaaaa cggtcacata accctgctgg
     2761 tctaacttgg caagcgttgt atagatctga ctgtgatggg cttcccaaaa aattgtgatc
     2821 agctgcttca attcataccc agaacgtggt ttggataaaa gcacgcataa taatatatag
     2881 gctaaagtat tcataaaaat cctacctctc gtcttatttt ctttattata tcacagtaaa
     2941 gtttccacgt tttacatgtg catattgaca tgtaaaataa atcatgtatg atgctaatag
     3001 agagaaaggg atggaaatat tggagaatca aatagatata caagaacaaa caaatgaaga
     3061 aacaaagggg aaaagttcag cgctagttgt agcagctacc tgtatgatcg cttttatggg
     3121 agtgggtcta gtagacccaa tcttaaaaac gattgctgca cagttaaacg ctacgccagc
     3181 tgaaacgacc ctgttattta ctagttacat gttagtcact ggtgtggtga tgctatttac
     3241 aggtttctta tctagtcgga tcggtttgaa aaaaacattg atgacaggat tgtttatcat
     3301 cgttgtattc gctggtcttg gcggattatc tgggaatatc ggaatgctga ttgggttacg
     3361 tgccggctgg ggtgtcggga atgctttatt tgtctctact gctttagcaa cgatcgtcag
     3421 tattttagtt ggtaacacag aaaaagcaat catgatgtat gaagcagcac ttggctgcgg
     3481 aatggctgtt ggccctctag tcggtggggt cttgggcagt ggttcatggc gttatccatt
     3541 ttttggggta gcatttttga tgttttgcgg ttttatagcc ctagcggtac ttttacctga
     3601 aactgagaaa ccaaagagaa aagtaggcct ttgggaaggt gtcaaagcgt taagcaatca
     3661 taaacttcgt tcagttggac taatcgcatt gttatataat ttcggattct ttactttact
     3721 tgcgtatgcg ccatttttat tgattggcta ttctgaatta gaagtcggtt ttgtattttt
     3781 tggctggggt gtgcttctgg ctattgcttc gattttcgtt gcaccggctc ttgagcggaa
     3841 gtttacgact tatcggacaa ttttagcagc atttgtctta ttcattattt gtttgctgtt
     3901 attaggagct ggaacttcta tgccagtcct tgtaccgatc agcattgtgt tagcaggatt
     3961 tttccaagga attatcaata cactgttgac gacgattgct atggaaatac caggtctgca
     4021 acgaaacgtt gcttcgtcca gctatagttt tgtccgcttt ttcggtggag ctttagcacc
     4081 atttattgca ggtgtgattg gtgaacatat tggtgaaagc tatgcgtttt attttgcagg
     4141 tgccattgtt cttatcagtg tatgttgtat catttatcac cgtaattatt ttgctacaaa
     4201 tgaagaagaa taagaaatca gaggttgtga aaaagctgtc ctgcatcaag tcataagaa
//
LOCUS       DADVXE010000225         2771 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.guided.151, whole genome shotgun sequence.
ACCESSION   DADVXE010000225 DADVXE010000000
VERSION     DADVXE010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.guided.151"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            110..193
                     /locus_tag="KB913_003062"
     CDS             110..193
                     /locus_tag="KB913_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBB6821324.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            318..1055
                     /gene="erm(B)"
                     /locus_tag="KB913_003063"
     CDS             318..1055
                     /gene="erm(B)"
                     /locus_tag="KB913_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBB6821325.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1318..2181)
                     /locus_tag="KB913_003064"
     CDS             complement(1318..2181)
                     /locus_tag="KB913_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6821326.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2183..2455)
                     /locus_tag="KB913_003065"
     CDS             complement(2183..2455)
                     /locus_tag="KB913_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBB6821327.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2472..2681)
                     /locus_tag="KB913_003066"
     CDS             complement(2472..2681)
                     /locus_tag="KB913_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBB6821328.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          851 a          487 c          443 g          990 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa attttgtata ataggaattg
       61 aagttaaatt agatgctaaa aatttgtaat taagaaggag ggattcgtca tgttggtatt
      121 ccaaatgcgt aatgtagata aaacatctac cgttttgaaa cagactaaaa acagtgatta
      181 cgcagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
      241 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttat agatgtaatc
      301 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
      361 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      421 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      481 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      541 ctcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      601 ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      661 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      721 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      781 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      841 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      901 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      961 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
     1021 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt ttgtaaattt
     1081 ggaaagttac acgttactaa agggaatgta gataaattat taggtatagg gcacctctaa
     1141 taactaccaa ttaattcacc tcaaaatgaa attagaaaaa aacagcgaaa tttttaaatc
     1201 tatttcttat cgatacaaat tcctcgtagg cgctcgggac cccaacatga ggaaatgttt
     1261 ttataaaaaa agagtagtta ccgttttttg gtaactactc ttttcctttt ttaaggttta
     1321 aatacctgga agtttaggtg ttttgggtat tggtggtgta ggtagctgca agctttccat
     1381 tttttgttga attgctttaa attcaggggt ttcttggtgt tgattttgaa ccattttttg
     1441 ctctattctc tccaaagtcg gttgaatttc tttccctgat actttacgat ttaattctct
     1501 ttctaaggtc tctttcggac taatggaagg cgtttctaag cttgaataga gtttcactcc
     1561 ttctctattg taaagcctta tatcgctaaa taagcccgtt ttatgaaggg tttctaaatt
     1621 ggtcggtaag tttttgacaa caatatcatg cgcttgtttt ggtgttgccc tagctgtcat
     1681 tggatcatct gcatacatgg tttcatatcg ttcaatcgtt cctaagtatg attcaatttt
     1741 cggtactgcc atgacgtata tttttgtttc ataaccttta gattgaagca ttgtggctgt
     1801 ttgaatggga acgtctgttg ttcgtcctgt tccttcaatc actaaattat agccttgatc
     1861 gcttaaacgg ctaataagtg cttctgtcat gcgattcgaa taaggggtaa cgtgttttac
     1921 tacgtctttt tcatagagtt tcactaattc gtcaaaattt gggtgctgtt gtttaaaggt
     1981 atcattatca atgacaataa cattcccttg tgtttcttca aaaattgctg atcgcaaact
     2041 ggttttccct gaccctggtt gcccaccaag taaaaaagcg gttggcgatt caaccgctag
     2101 tctattttta gttagtcgtt caacattctt ttctaaacga tcttcaaatt gcttttcggt
     2161 gaagtcagta atattcgcca tgttaagcca ctttctcttt attcaaaatt tgttttgaat
     2221 attgattcat tgaccgccaa tactcatgaa tagcttgtaa ttcttcaaat ggttgttgaa
     2281 ataaatcaac ttcttgtgcc acttctaatt gatttaaaag attcacttct agtaaacgag
     2341 tatttttagt atctagttca tgattcaaaa cataatttaa tacccgatta taaacacttg
     2401 ccgataactc attaatgatt tcaatttcaa atgttttttc atacgtaact gccatttcat
     2461 tttcactcct tttaaagttt gtcaggtaaa tatttccgta tatattcttc taaggcttga
     2521 tccataactt cttttacgtt tccgccattc tttgctgttt cgatttttat gatatggtgc
     2581 aagtcggcac gaacacgaac cgtcttatcc cccattatat ctttttttgc gctgattggc
     2641 gtatcatttc gttttgcttt ctgtgcgcct aaatttccca cgatcgctca cttctttcta
     2701 tttcttctta ctatttattt tatcatcacc tatcacaaat cacaagtgat ttgtgattaa
     2761 tcacttgtga t
//
LOCUS       DADVXE010000226          868 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303548-18
            SAMEA8426463-rid11941603.guided.206, whole genome shotgun sequence.
ACCESSION   DADVXE010000226 DADVXE010000000
VERSION     DADVXE010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426463
            Sequence Read Archive: ERR5555428
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005876.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005876.1
            Genome Coverage       :: 188x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 07:39:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,067
            CDSs (total)                      :: 3,001
            Genes (coding)                    :: 2,929
            CDSs (with protein)               :: 2,929
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 28 of 72
            Pseudo Genes (incomplete)         :: 35 of 72
            Pseudo Genes (internal stop)      :: 16 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426463-rid11941603.guided.206"
                     /isolate="303548-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-07"
     gene            255..803
                     /gene="aac(6')"
                     /locus_tag="KB913_003067"
     CDS             255..803
                     /gene="aac(6')"
                     /locus_tag="KB913_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBB6821329.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          311 a          127 c          182 g          248 t
ORIGIN      
        1 aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga acaaacagag
       61 ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag tgtttctgta
      121 taatttttta ttttataagt aagataaata atgaaagaat agagatactg attggtagct
      181 aaagattttt gagcgagaac atttcgtttt ttcaaaagga ctgttagaat aagcaagaac
      241 aagggggaag acgtatgata atcagtgaat ttgaccgtaa taatccagta ttgaaagatc
      301 agctttctga tttactgaga ctgacttggc cggaagaata tggagacagc tcggcagaag
      361 aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc agcggtagac caagatgagt
      421 tagtaggatt tattggtgca atccctcaat acggtatcac aggttgggaa ttgcatccat
      481 tagttgtaga aagctcccga cgaaagaacc aaataggtac tcgattagtc aattacttag
      541 aaaaagaagt agcttccaga ggaggaatca cgatttattt aggtacggat gatttagacc
      601 atggaacaac gttaagtcaa acggacctgt atgagcatac atttgataaa gtggcttcca
      661 tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa attaggttat aaaatcgtag
      721 gtgtcttacc aaatgcaaat ggctgggaca aaccggatat ttggatggca aaaacgatta
      781 ttcctcgacc aaattctcaa taataaaaag aggttgtgac agaagtaatc agcttcaaga
      841 aataagaagg aatttacgaa aattactt
//
